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Search of human proteins with 21040249
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21040249 retinoic acid early transcript 1E [Homo sapiens]
(263 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21040249 retinoic acid early transcript 1E [Homo sapiens] 549 e-157
gi|13376826 UL16 binding protein 1 [Homo sapiens] 159 2e-39
gi|13375656 UL16 binding protein 3 [Homo sapiens] 158 4e-39
gi|130484306 retinoic acid early transcript 1G [Homo sapiens] 130 9e-31
gi|126723295 retinoic acid early transcript 1L [Homo sapiens] 129 3e-30
gi|13376824 UL16 binding protein 2 [Homo sapiens] 128 6e-30
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 57 2e-08
gi|167857788 MHC class I polypeptide-related sequence B [Homo sa... 56 3e-08
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 56 4e-08
gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi... 55 5e-08
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 55 5e-08
gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H... 52 7e-07
gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom... 52 7e-07
gi|4504417 major histocompatibility complex, class I-related [Ho... 50 2e-06
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 44 1e-04
gi|17986001 major histocompatibility complex, class I, B precurs... 42 7e-04
gi|24797067 major histocompatibility complex, class I, A precurs... 42 7e-04
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 41 0.001
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 40 0.003
gi|62912479 major histocompatibility complex, class I, E precurs... 39 0.005
gi|4504415 major histocompatibility complex, class I, G precurso... 36 0.030
gi|30026034 solute carrier family 35, member B2 [Homo sapiens] 35 0.051
gi|149158700 major histocompatibility complex, class I, F isofor... 33 0.25
gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa... 32 0.57
gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sa... 32 0.57
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 32 0.74
gi|30425462 hypothetical protein LOC284185 [Homo sapiens] 30 1.6
gi|149158702 major histocompatibility complex, class I, F isofor... 29 3.7
gi|149158698 major histocompatibility complex, class I, F isofor... 29 3.7
gi|9625002 integrin, beta 6 [Homo sapiens] 29 3.7
>gi|21040249 retinoic acid early transcript 1E [Homo sapiens]
Length = 263
Score = 549 bits (1415), Expect = e-157
Identities = 263/263 (100%), Positives = 263/263 (100%)
Query: 1 MRRISLTSSPVRLLLFLLLLLIALEIMVGGHSLCFNFTIKSLSRPGQPWCEAQVFLNKNL 60
MRRISLTSSPVRLLLFLLLLLIALEIMVGGHSLCFNFTIKSLSRPGQPWCEAQVFLNKNL
Sbjct: 1 MRRISLTSSPVRLLLFLLLLLIALEIMVGGHSLCFNFTIKSLSRPGQPWCEAQVFLNKNL 60
Query: 61 FLQYNSDNNMVKPLGLLGKKVYATSTWGELTQTLGEVGRDLRMLLCDIKPQIKTSDPSTL 120
FLQYNSDNNMVKPLGLLGKKVYATSTWGELTQTLGEVGRDLRMLLCDIKPQIKTSDPSTL
Sbjct: 61 FLQYNSDNNMVKPLGLLGKKVYATSTWGELTQTLGEVGRDLRMLLCDIKPQIKTSDPSTL 120
Query: 121 QVEMFCQREAERCTGASWQFATNGEKSLLFDAMNMTWTVINHEASKIKETWKKDRGLEKY 180
QVEMFCQREAERCTGASWQFATNGEKSLLFDAMNMTWTVINHEASKIKETWKKDRGLEKY
Sbjct: 121 QVEMFCQREAERCTGASWQFATNGEKSLLFDAMNMTWTVINHEASKIKETWKKDRGLEKY 180
Query: 181 FRKLSKGDCDHWLREFLGHWEAMPEPTVSPVNASDIHWSSSSLPDRWIILGAFILLVLMG 240
FRKLSKGDCDHWLREFLGHWEAMPEPTVSPVNASDIHWSSSSLPDRWIILGAFILLVLMG
Sbjct: 181 FRKLSKGDCDHWLREFLGHWEAMPEPTVSPVNASDIHWSSSSLPDRWIILGAFILLVLMG 240
Query: 241 IVLICVWWQNGEWQAGLWPLRTS 263
IVLICVWWQNGEWQAGLWPLRTS
Sbjct: 241 IVLICVWWQNGEWQAGLWPLRTS 263
>gi|13376826 UL16 binding protein 1 [Homo sapiens]
Length = 244
Score = 159 bits (403), Expect = 2e-39
Identities = 93/243 (38%), Positives = 132/243 (54%), Gaps = 6/243 (2%)
Query: 4 ISLTSSPVRLLLFLLLLLIALEIMVGG---HSLCFNFTIKSLSRPGQPWCEAQVFLNKNL 60
++ +SP LL LL L++ G H LC++F I SRP WCE Q +++
Sbjct: 1 MAAAASPAFLLCLPLLHLLSGWSRAGWVDTHCLCYDFIITPKSRPEPQWCEVQGLVDERP 60
Query: 61 FLQYNSDNNMVKPLGLLGKKVYATSTWGELTQTLGEVGRDLRMLLCDIKPQ-IKTSDPST 119
FL Y+ N+ K LGKKV T TW E T+TL +V L+ L DI+ + + +P T
Sbjct: 61 FLHYDCVNHKAKAFASLGKKVNVTKTWEEQTETLRDVVDFLKGQLLDIQVENLIPIEPLT 120
Query: 120 LQVEMFCQREAERCTGASWQFATNGEKSLLFDAMNMTWTVINHEASKIKETWKKDRGLEK 179
LQ M C+ EA SWQF NG+K LLFD+ N WT ++ A K+ E W+K+R +
Sbjct: 121 LQARMSCEHEAHGHGRGSWQFLFNGQKFLLFDSNNRKWTALHPGAKKMTEKWEKNRDVTM 180
Query: 180 YFRKLSKGDCDHWLREFLGHWEAMPEPTVSPVNASDIHW--SSSSLPDRWIILGAFILLV 237
+F+K+S GDC WL EFL +WE M +PT P A + ++ W +L F+ +
Sbjct: 181 FFQKISLGDCKMWLEEFLMYWEQMLDPTKPPSLAPGTTQPKAMATTLSPWSLLIIFLCFI 240
Query: 238 LMG 240
L G
Sbjct: 241 LAG 243
>gi|13375656 UL16 binding protein 3 [Homo sapiens]
Length = 244
Score = 158 bits (400), Expect = 4e-39
Identities = 87/210 (41%), Positives = 126/210 (60%), Gaps = 5/210 (2%)
Query: 31 HSLCFNFTIKSLSRPGQPWCEAQVFLNKNLFLQYNSDNNMVKPLGLLGKKVYATSTWGEL 90
HSL +NFTI L R GQ WCE Q +++ FL Y+ ++ V +G L +++YAT WG+
Sbjct: 32 HSLWYNFTIIHLPRHGQQWCEVQSQVDQKNFLSYDCGSDKVLSMGHLEEQLYATDAWGKQ 91
Query: 91 TQTLGEVGRDLRMLLCDIKPQIKT-SDPSTLQVEMFCQREAERCTGASWQFATNGEKSLL 149
+ L EVG+ LR+ L D + + T S P TLQV M C+ EA+ SWQF+ +G K LL
Sbjct: 92 LEMLREVGQRLRLELADTELEDFTPSGPLTLQVRMSCECEADGYIRGSWQFSFDGRKFLL 151
Query: 150 FDAMNMTWTVINHEASKIKETWKKDRGLEKYFRKLSKGDCDHWLREFLGHWEAMPEPTVS 209
FD+ N WTV++ A ++KE W+KD GL +F+ +S DC WLR+FL H + EPT
Sbjct: 152 FDSNNRKWTVVHAGARRMKEKWEKDSGLTTFFKMVSMRDCKSWLRDFLMHRKKRLEPTAP 211
Query: 210 PVNASDIHW----SSSSLPDRWIILGAFIL 235
P A + +++ P ++I+ FIL
Sbjct: 212 PTMAPGLAQPKAIATTLSPWSFLIILCFIL 241
>gi|130484306 retinoic acid early transcript 1G [Homo sapiens]
Length = 334
Score = 130 bits (328), Expect = 9e-31
Identities = 81/246 (32%), Positives = 124/246 (50%), Gaps = 8/246 (3%)
Query: 4 ISLTSSPVRLLLFLLLLLIALEIMVG---GHSLCFNFTIKSLSRPGQPWCEAQVFLNKNL 60
++ +SP LL LLLL++ G HSLC++ T+ RPG WC Q +++
Sbjct: 1 MAAAASPAFLLRLPLLLLLSSWCRTGLADPHSLCYDITVIPKFRPGPRWCAVQGQVDEKT 60
Query: 61 FLQYNSDNNMVKPLGLLGKKVYATSTWGELTQTLGEVGRDLRMLLCDIKPQ-IKTSDPST 119
FL Y+ + V P+ LGKK+ T+ W L EV L L DI+ + +P T
Sbjct: 61 FLHYDCGSKTVTPVSPLGKKLNVTTAWKAQNPVLREVVDILTEQLLDIQLENYIPKEPLT 120
Query: 120 LQVEMFCQREAERCTGASWQFATNGEKSLLFDAMNMTWTVINHEASKIKETWKKDRGLEK 179
LQ M C+++AE SWQ + +G+ LLFD+ N WT ++ A K+KE W+ D+ +
Sbjct: 121 LQARMSCEQKAEGHGSGSWQLSFDGQIFLLFDSENRMWTTVHPGARKMKEKWENDKDMTM 180
Query: 180 YFRKLSKGDCDHWLREFLGHWEAMPEPTVSPVNASDIHWSSSSLPDRWIILGAFILLVLM 239
F +S GDC WL +FL ++ T+ P + SS + R + +L+
Sbjct: 181 SFHYISMGDCTGWLEDFLMGMDS----TLEPSAGAPPTMSSGTAQPRATATTLILCCLLI 236
Query: 240 GIVLIC 245
+LIC
Sbjct: 237 MCLLIC 242
>gi|126723295 retinoic acid early transcript 1L [Homo sapiens]
Length = 246
Score = 129 bits (323), Expect = 3e-30
Identities = 67/178 (37%), Positives = 98/178 (55%), Gaps = 1/178 (0%)
Query: 31 HSLCFNFTIKSLSRPGQPWCEAQVFLNKNLFLQYNSDNNMVKPLGLLGKKVYATSTWGEL 90
HSLC++ T+ RPG WC Q +++ FL Y+ N V P+ LGKK+ T W
Sbjct: 31 HSLCYDITVIPKFRPGPRWCAVQGQVDEKTFLHYDCGNKTVTPVSPLGKKLNVTMAWKAQ 90
Query: 91 TQTLGEVGRDLRMLLCDIKPQIKT-SDPSTLQVEMFCQREAERCTGASWQFATNGEKSLL 149
L EV L L DI+ + T +P TLQ M C+++AE + SWQF+ +G+ LL
Sbjct: 91 NPVLREVVDILTEQLLDIQLENYTPKEPLTLQARMSCEQKAEGHSSGSWQFSIDGQTFLL 150
Query: 150 FDAMNMTWTVINHEASKIKETWKKDRGLEKYFRKLSKGDCDHWLREFLGHWEAMPEPT 207
FD+ WT ++ A K+KE W+ D+ + F +S GDC WL +FL ++ EP+
Sbjct: 151 FDSEKRMWTTVHPGARKMKEKWENDKDVAMSFHYISMGDCIGWLEDFLMGMDSTLEPS 208
>gi|13376824 UL16 binding protein 2 [Homo sapiens]
Length = 246
Score = 128 bits (321), Expect = 6e-30
Identities = 74/205 (36%), Positives = 110/205 (53%), Gaps = 5/205 (2%)
Query: 8 SSPVRLLLFLLLLLIALEIMVGG----HSLCFNFTIKSLSRPGQPWCEAQVFLNKNLFLQ 63
++ ++LL L LLL+ G HSLC++ T+ RPG WC Q +++ FL
Sbjct: 4 AAATKILLCLPLLLLLSGWSRAGRADPHSLCYDITVIPKFRPGPRWCAVQGQVDEKTFLH 63
Query: 64 YNSDNNMVKPLGLLGKKVYATSTWGELTQTLGEVGRDLRMLLCDIKPQIKT-SDPSTLQV 122
Y+ N V P+ LGKK+ T+ W L EV L L DI+ + T +P TLQ
Sbjct: 64 YDCGNKTVTPVSPLGKKLNVTTAWKAQNPVLREVVDILTEQLRDIQLENYTPKEPLTLQA 123
Query: 123 EMFCQREAERCTGASWQFATNGEKSLLFDAMNMTWTVINHEASKIKETWKKDRGLEKYFR 182
M C+++AE + SWQF+ +G+ LLFD+ WT ++ A K+KE W+ D+ + F
Sbjct: 124 RMSCEQKAEGHSSGSWQFSFDGQIFLLFDSEKRMWTTVHPGARKMKEKWENDKVVAMSFH 183
Query: 183 KLSKGDCDHWLREFLGHWEAMPEPT 207
S GDC WL +FL ++ EP+
Sbjct: 184 YFSMGDCIGWLEDFLMGMDSTLEPS 208
>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
sapiens]
Length = 334
Score = 56.6 bits (135), Expect = 2e-08
Identities = 47/220 (21%), Positives = 92/220 (41%), Gaps = 1/220 (0%)
Query: 10 PVRLLLFLLLLLIALEIMVGGHSLCFNFTIKSLSRPGQPWCEAQVFLNKNLFLQYNSDNN 69
P LLL LL + ++ HSL + F S G EA +++ LF+ Y+ ++
Sbjct: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
Query: 70 MVKPLGLLGKKVYATSTWGELTQTLGEVGRDLRMLLCDIKPQIKTSDPS-TLQVEMFCQR 128
V+P ++ W +L+Q+L + I S S TLQV + C+
Sbjct: 67 RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEM 126
Query: 129 EAERCTGASWQFATNGEKSLLFDAMNMTWTVINHEASKIKETWKKDRGLEKYFRKLSKGD 188
+ + T W++ +G+ L F + W A K W++ + + R + D
Sbjct: 127 QEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERD 186
Query: 189 CDHWLREFLGHWEAMPEPTVSPVNASDIHWSSSSLPDRWI 228
C L++ L + + V+ + +++ ++ +W+
Sbjct: 187 CPAQLQQLLELGRGVLDQQVTTLRCRALNYYPQNITMKWL 226
>gi|167857788 MHC class I polypeptide-related sequence B [Homo
sapiens]
Length = 383
Score = 56.2 bits (134), Expect = 3e-08
Identities = 51/189 (26%), Positives = 73/189 (38%), Gaps = 7/189 (3%)
Query: 31 HSLCFNFTIKSLSRPGQPWCEAQVFLNKNLFLQYNSDNNMVKPLGLLGKKVYATSTWGEL 90
HSL +N + S Q A+ L+ FL+Y+ KP G + V TW
Sbjct: 26 HSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTWDTE 85
Query: 91 TQTLGEVGRDLRMLLCDIKPQIKTSDPSTLQVEMFCQREAERCTGASWQFATNGEKSLLF 150
T+ L E G+DLR L IK Q +LQ C+ + T S F +GE L
Sbjct: 86 TEDLTENGQDLRRTLTHIKDQ--KGGLHSLQEIRVCEIHEDSSTRGSRHFYYDGELFLSQ 143
Query: 151 DAMNMTWTVINHE-----ASKIKETWKKDRGLEKYFRKLSKGDCDHWLREFLGHWEAMPE 205
+ TV A + WK+D K + + DC L+ +L A+
Sbjct: 144 NLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSGVAIRR 203
Query: 206 PTVSPVNAS 214
VN +
Sbjct: 204 TVPPMVNVT 212
>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
Length = 298
Score = 55.8 bits (133), Expect = 4e-08
Identities = 54/192 (28%), Positives = 89/192 (46%), Gaps = 7/192 (3%)
Query: 11 VRLLLFLLLLL---IALEIMVGGHSLCFNFTIKSLSRPGQPWCEAQVFLNKNLFLQYNSD 67
V +LL LLLLL + E G +SL + +T S P +A LN F +YNS
Sbjct: 5 VPVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSK 64
Query: 68 NNMVKPLGLLGKKVYATSTWGELTQTLGEVGRDLRM-LLCDIKPQIKTSDPS-TLQVEMF 125
+ +P+GL ++V W + +Q L + D+ M L DI S+ S LQ
Sbjct: 65 DRKSQPMGLW-RQVEGMEDWKQDSQ-LQKAREDIFMETLKDIVEYYNDSNGSHVLQGRFG 122
Query: 126 CQREAERCTGASWQFATNGEKSLLFDAMNMTWTVINHEASKIKETWKKDRGLEKYFRKLS 185
C+ E R +GA W++ +G+ + F+ W + A K+ W+ + + +
Sbjct: 123 CEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYL 182
Query: 186 KGDCDHWLREFL 197
+ +C LR++L
Sbjct: 183 EEECPATLRKYL 194
>gi|4557751 MHC class I polypeptide-related sequence A [Homo
sapiens]
Length = 383
Score = 55.5 bits (132), Expect = 5e-08
Identities = 48/172 (27%), Positives = 68/172 (39%), Gaps = 7/172 (4%)
Query: 31 HSLCFNFTIKSLSRPGQPWCEAQVFLNKNLFLQYNSDNNMVKPLGLLGKKVYATSTWGEL 90
HSL +N T+ S Q +V L+ FL+ + KP G + V TW
Sbjct: 26 HSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQKCRAKPQGQWAEDVLGNKTWDRE 85
Query: 91 TQTLGEVGRDLRMLLCDIKPQIKTSDPSTLQVEMFCQREAERCTGASWQFATNGEKSLLF 150
T+ L G+DLRM L IK Q +LQ C+ + T +S F +GE L
Sbjct: 86 TRDLTGNGKDLRMTLAHIKDQ--KEGLHSLQEIRVCEIHEDNSTRSSQHFYYDGELFLSQ 143
Query: 151 DAMNMTWTVINHE-----ASKIKETWKKDRGLEKYFRKLSKGDCDHWLREFL 197
+ WT+ A ++ K+D K DC LR +L
Sbjct: 144 NLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADCLQELRRYL 195
>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
sapiens]
Length = 348
Score = 55.5 bits (132), Expect = 5e-08
Identities = 50/213 (23%), Positives = 88/213 (41%), Gaps = 1/213 (0%)
Query: 10 PVRLLLFLLLLLIALEIMVGGHSLCFNFTIKSLSRPGQPWCEAQVFLNKNLFLQYNSDNN 69
P LLL LL + ++ HSL + F S G EA +++ LF+ Y+ ++
Sbjct: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
Query: 70 MVKPLGLLGKKVYATSTWGELTQTLGEVGRDLRMLLCDIKPQIKTSDPS-TLQVEMFCQR 128
V+P ++ W +L+Q+L + I S S TLQV + C+
Sbjct: 67 RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEM 126
Query: 129 EAERCTGASWQFATNGEKSLLFDAMNMTWTVINHEASKIKETWKKDRGLEKYFRKLSKGD 188
+ + T W++ +G+ L F + W A K W++ + + R + D
Sbjct: 127 QEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERD 186
Query: 189 CDHWLREFLGHWEAMPEPTVSPVNASDIHWSSS 221
C L++ L + + V P+ H +SS
Sbjct: 187 CPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSS 219
>gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 51.6 bits (122), Expect = 7e-07
Identities = 52/185 (28%), Positives = 76/185 (41%), Gaps = 7/185 (3%)
Query: 15 LFLLLLLIALEIMVGGH-SLCFNFTIKSLSRPGQPWCEAQVFLNKNLFLQYNSDNNMVKP 73
L LLL L+ + H SL ++ T S PG P +L +L YNS +P
Sbjct: 11 LGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEP 70
Query: 74 LGLLGKKVYATSTWGELTQTLGEVGRDLRMLLCDIKPQIKTSDPSTLQVEMFCQREAERC 133
G + + W + T L R L + + P TLQ + C+ +
Sbjct: 71 CGAWVWENQVSWYWEKETTDL----RIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNT 126
Query: 134 TGASWQFATNGEKSLLFDAMNMTWTVINHEASKIKETW-KKDRGLEKYFRKLSKGDCDHW 192
+ + +FA NGE+ + FD TW EA I + W ++D+ K L C H
Sbjct: 127 SVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFL-LFSCPHR 185
Query: 193 LREFL 197
LRE L
Sbjct: 186 LREHL 190
>gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 51.6 bits (122), Expect = 7e-07
Identities = 52/185 (28%), Positives = 76/185 (41%), Gaps = 7/185 (3%)
Query: 15 LFLLLLLIALEIMVGGH-SLCFNFTIKSLSRPGQPWCEAQVFLNKNLFLQYNSDNNMVKP 73
L LLL L+ + H SL ++ T S PG P +L +L YNS +P
Sbjct: 11 LGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEP 70
Query: 74 LGLLGKKVYATSTWGELTQTLGEVGRDLRMLLCDIKPQIKTSDPSTLQVEMFCQREAERC 133
G + + W + T L R L + + P TLQ + C+ +
Sbjct: 71 CGAWVWENQVSWYWEKETTDL----RIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNT 126
Query: 134 TGASWQFATNGEKSLLFDAMNMTWTVINHEASKIKETW-KKDRGLEKYFRKLSKGDCDHW 192
+ + +FA NGE+ + FD TW EA I + W ++D+ K L C H
Sbjct: 127 SVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFL-LFSCPHR 185
Query: 193 LREFL 197
LRE L
Sbjct: 186 LREHL 190
>gi|4504417 major histocompatibility complex, class I-related [Homo
sapiens]
Length = 341
Score = 50.1 bits (118), Expect = 2e-06
Identities = 45/202 (22%), Positives = 87/202 (43%), Gaps = 3/202 (1%)
Query: 13 LLLFLLLLLIALEIMVGG---HSLCFNFTIKSLSRPGQPWCEAQVFLNKNLFLQYNSDNN 69
L+ FLL L+I L + HSL + S G P + +++ + Y+S
Sbjct: 4 LMAFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTR 63
Query: 70 MVKPLGLLGKKVYATSTWGELTQTLGEVGRDLRMLLCDIKPQIKTSDPSTLQVEMFCQRE 129
+P + A W TQ L + ++ L ++ S T Q + C+
Sbjct: 64 QKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGCELL 123
Query: 130 AERCTGASWQFATNGEKSLLFDAMNMTWTVINHEASKIKETWKKDRGLEKYFRKLSKGDC 189
+ T Q+A +G+ L+F+ ++W +++ A IK+ W+ ++ Y + + +C
Sbjct: 124 EDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEEC 183
Query: 190 DHWLREFLGHWEAMPEPTVSPV 211
WL+ FL + + + T P+
Sbjct: 184 IAWLKRFLEYGKDTLQRTEPPL 205
>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
sapiens]
Length = 325
Score = 44.3 bits (103), Expect = 1e-04
Identities = 36/168 (21%), Positives = 70/168 (41%), Gaps = 1/168 (0%)
Query: 55 FLNKNLFLQYNSDNNMVKPLGLLGKKVYATSTWGELTQTLGEVGRDLRMLLCDIKPQIKT 114
+++ LF+ Y+ ++ V+P ++ W +L+Q+L + I
Sbjct: 29 YVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNH 88
Query: 115 SDPS-TLQVEMFCQREAERCTGASWQFATNGEKSLLFDAMNMTWTVINHEASKIKETWKK 173
S S TLQV + C+ + + T W++ +G+ L F + W A K W++
Sbjct: 89 SKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWER 148
Query: 174 DRGLEKYFRKLSKGDCDHWLREFLGHWEAMPEPTVSPVNASDIHWSSS 221
+ + R + DC L++ L + + V P+ H +SS
Sbjct: 149 HKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSS 196
>gi|17986001 major histocompatibility complex, class I, B precursor
[Homo sapiens]
Length = 362
Score = 41.6 bits (96), Expect = 7e-04
Identities = 48/199 (24%), Positives = 86/199 (43%), Gaps = 11/199 (5%)
Query: 6 LTSSPVRLLLFLLLLLIALEIMVGGHSLCFNFTIKSLSRPG--QPWCEAQVFLNKNLFLQ 63
L +P +LL L L E G HS+ + +T S+SRPG +P + +++ F++
Sbjct: 2 LVMAPRTVLLLLSAALALTETWAGSHSMRYFYT--SVSRPGRGEPRFISVGYVDDTQFVR 59
Query: 64 YNSD--NNMVKPLGLLGKKVYATSTWGELTQTLGEVGRDLRMLLCDIKPQIKTSDPS--T 119
++SD + +P ++ W TQ + R L +++ S+ T
Sbjct: 60 FDSDAASPREEPRAPWIEQE-GPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHT 118
Query: 120 LQVEMFCQREAE-RCTGASWQFATNGEKSLLFDAMNMTWTVINHEASKIKETWKKDRGLE 178
LQ C + R Q+A +G+ + + +WT + A + W+ R E
Sbjct: 119 LQSMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAE 178
Query: 179 KYFRKLSKGDCDHWLREFL 197
+ R +G+C WLR +L
Sbjct: 179 QR-RAYLEGECVEWLRRYL 196
>gi|24797067 major histocompatibility complex, class I, A precursor
[Homo sapiens]
Length = 365
Score = 41.6 bits (96), Expect = 7e-04
Identities = 49/209 (23%), Positives = 91/209 (43%), Gaps = 11/209 (5%)
Query: 9 SPVRLLLFLLLLLIALEIMVGGHSLCFNFTIKSLSRP--GQPWCEAQVFLNKNLFLQYNS 66
+P LLL L L + G HS+ + FT S+SRP G+P A +++ F++++S
Sbjct: 5 APRTLLLLLSGALALTQTWAGSHSMRYFFT--SVSRPGRGEPRFIAVGYVDDTQFVRFDS 62
Query: 67 D--NNMVKPLGLLGKKVYATSTWGELTQTLGEVGRDLRMLLCDIKPQIKTSDPS--TLQV 122
D + ++P ++ W + T+ + + R+ L ++ S+ T+Q+
Sbjct: 63 DAASQRMEPRAPWIEQ-EGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQI 121
Query: 123 EMFCQREAE-RCTGASWQFATNGEKSLLFDAMNMTWTVINHEASKIKETWKKDRGLEKYF 181
C ++ R Q A +G+ + + +WT + A K W+ E+
Sbjct: 122 MYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEAEQ-L 180
Query: 182 RKLSKGDCDHWLREFLGHWEAMPEPTVSP 210
R G C WLR +L + + + T P
Sbjct: 181 RAYLDGTCVEWLRRYLENGKETLQRTDPP 209
>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
sapiens]
Length = 246
Score = 40.8 bits (94), Expect = 0.001
Identities = 26/128 (20%), Positives = 54/128 (42%)
Query: 101 LRMLLCDIKPQIKTSDPSTLQVEMFCQREAERCTGASWQFATNGEKSLLFDAMNMTWTVI 160
L MLL Q + TLQV + C+ + + T W++ +G+ L F + W
Sbjct: 11 LLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAA 70
Query: 161 NHEASKIKETWKKDRGLEKYFRKLSKGDCDHWLREFLGHWEAMPEPTVSPVNASDIHWSS 220
A K W++ + + R + DC L++ L + + V+ + +++
Sbjct: 71 EPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVTTLRCRALNYYP 130
Query: 221 SSLPDRWI 228
++ +W+
Sbjct: 131 QNITMKWL 138
>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
sapiens]
Length = 260
Score = 39.7 bits (91), Expect = 0.003
Identities = 29/121 (23%), Positives = 50/121 (41%)
Query: 101 LRMLLCDIKPQIKTSDPSTLQVEMFCQREAERCTGASWQFATNGEKSLLFDAMNMTWTVI 160
L MLL Q + TLQV + C+ + + T W++ +G+ L F + W
Sbjct: 11 LLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAA 70
Query: 161 NHEASKIKETWKKDRGLEKYFRKLSKGDCDHWLREFLGHWEAMPEPTVSPVNASDIHWSS 220
A K W++ + + R + DC L++ L + + V P+ H +S
Sbjct: 71 EPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTS 130
Query: 221 S 221
S
Sbjct: 131 S 131
>gi|62912479 major histocompatibility complex, class I, E precursor
[Homo sapiens]
Length = 358
Score = 38.9 bits (89), Expect = 0.005
Identities = 46/193 (23%), Positives = 86/193 (44%), Gaps = 13/193 (6%)
Query: 13 LLLFLLLLLIALEIMVGGHSLCFNFTIKSLSRP--GQPWCEAQVFLNKNLFLQYNSD--- 67
LLL L L + G HSL + T S+SRP G+P + +++ F+++++D
Sbjct: 6 LLLLLSEALALTQTWAGSHSLKYFHT--SVSRPGRGEPRFISVGYVDDTQFVRFDNDAAS 63
Query: 68 NNMVKPLGLLGKKVYATSTWGELTQTLGEVGRDLRMLLCDIKPQIKTSDPS--TLQVEMF 125
MV + ++ + W T++ + + R+ L ++ S+ TLQ
Sbjct: 64 PRMVPRAPWMEQE--GSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG 121
Query: 126 CQREAE-RCTGASWQFATNGEKSLLFDAMNMTWTVINHEASKIKETWKKDRGLEKYFRKL 184
C+ + R QFA +G+ L + +WT ++ A++I E D ++ R
Sbjct: 122 CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVD-TAAQISEQKSNDASEAEHQRAY 180
Query: 185 SKGDCDHWLREFL 197
+ C WL ++L
Sbjct: 181 LEDTCVEWLHKYL 193
>gi|4504415 major histocompatibility complex, class I, G precursor
[Homo sapiens]
Length = 338
Score = 36.2 bits (82), Expect = 0.030
Identities = 47/202 (23%), Positives = 89/202 (44%), Gaps = 11/202 (5%)
Query: 9 SPVRLLLFLLLLLIALEIMVGGHSLCFNFTIKSLSRP--GQPWCEAQVFLNKNLFLQYNS 66
+P L L L L E G HS+ + ++SRP G+P A +++ F++++S
Sbjct: 5 APRTLFLLLSGALTLTETWAGSHSM--RYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDS 62
Query: 67 DN--NMVKPLGLLGKKVYATSTWGELTQTLGEVGRDLRMLLCDIKPQIKTSDPS--TLQV 122
D+ ++P ++ W E T+ + RM L ++ S+ S TLQ
Sbjct: 63 DSACPRMEPRAPWVEQ-EGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQW 121
Query: 123 EMFCQREAE-RCTGASWQFATNGEKSLLFDAMNMTWTVINHEASKIKETWKKDRGLEKYF 181
+ C ++ R Q+A +G+ L + +WT + A++I + + + +
Sbjct: 122 MIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAAD-TAAQISKRKCEAANVAEQR 180
Query: 182 RKLSKGDCDHWLREFLGHWEAM 203
R +G C WL +L + + M
Sbjct: 181 RAYLEGTCVEWLHRYLENGKEM 202
>gi|30026034 solute carrier family 35, member B2 [Homo sapiens]
Length = 432
Score = 35.4 bits (80), Expect = 0.051
Identities = 34/118 (28%), Positives = 54/118 (45%), Gaps = 15/118 (12%)
Query: 16 FLLLLLIALEIMVGGHS--LC---------FNFTIKSLSRPGQPWCEAQVFLNKNLFLQY 64
FL+L+ L ++V G S LC + ++ SLS WC+ + + Q
Sbjct: 154 FLVLMNRVLALIVAGLSCVLCKQPRHGAPMYRYSFASLSNVLSSWCQYEALKFVSFPTQV 213
Query: 65 NSDNNMVKPLGLLGKKVYATS--TWGELTQTLGEVGRDLRMLLCDIKPQIKTSDPSTL 120
+ + V P+ L+GK V S W LT TL +G + M L P+ ++S +TL
Sbjct: 214 LAKASKVIPVMLMGKLVSRRSYEHWEYLTATLISIG--VSMFLLSSGPEPRSSPATTL 269
>gi|149158700 major histocompatibility complex, class I, F isoform 3
precursor [Homo sapiens]
Length = 254
Score = 33.1 bits (74), Expect = 0.25
Identities = 57/254 (22%), Positives = 101/254 (39%), Gaps = 30/254 (11%)
Query: 9 SPVRLLLFLLLLLIALEIMVGGHSLCFNFTIKSLSRPGQPWCEAQVFLNKNLFLQYNSDN 68
+P LLL L L + G HSL + T S G+P A +++ FL+++SD
Sbjct: 2 APRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDA 61
Query: 69 NM--VKPLGLLGKKVYATSTWGELTQTLGEVGRDLRMLLCDIKPQIKTSDPS--TLQVEM 124
+ ++P ++ W T + R+ L ++ + S+ TLQ
Sbjct: 62 AIPRMEPREPWVEQ-EGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
Query: 125 FCQREAE-RCTGASWQFATNGEKSLLFDAMNMTWTVINHEASKIKETWKKDRGLEKYFRK 183
C + R Q A +G+ + + +WT + A + ++ + E+ FR
Sbjct: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEE-FRT 179
Query: 184 LSKGDCDHWLREFLGHW-------EAMPEPTVSPVNASDIHWSSSSLPDRWIILGAFIL- 235
+G+C LR +L + E P+PT+ V I+ G +L
Sbjct: 180 YLEGECLELLRRYLENGKETLQRAEQSPQPTIPIVG---------------IVAGLVVLG 224
Query: 236 LVLMGIVLICVWWQ 249
V+ G V+ V W+
Sbjct: 225 AVVTGAVVAAVMWR 238
>gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
sapiens]
Length = 256
Score = 32.0 bits (71), Expect = 0.57
Identities = 23/85 (27%), Positives = 40/85 (47%)
Query: 10 PVRLLLFLLLLLIALEIMVGGHSLCFNFTIKSLSRPGQPWCEAQVFLNKNLFLQYNSDNN 69
P LLL LL + ++ HSL + F S G EA +++ LF+ Y+ ++
Sbjct: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
Query: 70 MVKPLGLLGKKVYATSTWGELTQTL 94
V+P ++ W +L+Q+L
Sbjct: 67 RVEPRTPWVSSRISSQMWLQLSQSL 91
>gi|21040341 hemochromatosis protein isoform 3 precursor [Homo
sapiens]
Length = 242
Score = 32.0 bits (71), Expect = 0.57
Identities = 23/85 (27%), Positives = 40/85 (47%)
Query: 10 PVRLLLFLLLLLIALEIMVGGHSLCFNFTIKSLSRPGQPWCEAQVFLNKNLFLQYNSDNN 69
P LLL LL + ++ HSL + F S G EA +++ LF+ Y+ ++
Sbjct: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
Query: 70 MVKPLGLLGKKVYATSTWGELTQTL 94
V+P ++ W +L+Q+L
Sbjct: 67 RVEPRTPWVSSRISSQMWLQLSQSL 91
>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
sapiens]
Length = 366
Score = 31.6 bits (70), Expect = 0.74
Identities = 37/173 (21%), Positives = 74/173 (42%), Gaps = 5/173 (2%)
Query: 29 GGHSLCFNFTIKSLSRPGQPWCEAQVFLNKNLFLQYNSDN-NMVKPLGLLGKKVYATSTW 87
G HSL + +T S G+P + +++ F++++SD+ N + + W
Sbjct: 38 GSHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQEGPEYW 97
Query: 88 GELTQTLGEVGRDLRMLLCDIKPQIKTSDPS--TLQVEMFCQREAE-RCTGASWQFATNG 144
E T+ + + + R+ L ++ S+ TLQ+ C + R Q A +G
Sbjct: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDG 157
Query: 145 EKSLLFDAMNMTWTVINHEASKIKETWKKDRGLEKYFRKLSKGDCDHWLREFL 197
+ + +WT + A++I + ++ G + R +G C LR +L
Sbjct: 158 RDYIALNEDLRSWTAAD-TAAQITKRKREAAGAAERQRNYLEGRCVEGLRRYL 209
>gi|30425462 hypothetical protein LOC284185 [Homo sapiens]
Length = 264
Score = 30.4 bits (67), Expect = 1.6
Identities = 13/36 (36%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Query: 200 WEAMPEPTVSPVNAS-DIHWSSSSLPDRWIILGAFI 234
W PT SP AS D+H +S ++P W++ G +
Sbjct: 26 WYRAAHPTTSPTAASRDVHPASGAVPGPWLVEGTAV 61
>gi|149158702 major histocompatibility complex, class I, F isoform
1 precursor [Homo sapiens]
Length = 442
Score = 29.3 bits (64), Expect = 3.7
Identities = 19/59 (32%), Positives = 29/59 (49%)
Query: 9 SPVRLLLFLLLLLIALEIMVGGHSLCFNFTIKSLSRPGQPWCEAQVFLNKNLFLQYNSD 67
+P LLL L L + G HSL + T S G+P A +++ FL+++SD
Sbjct: 2 APRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
>gi|149158698 major histocompatibility complex, class I, F isoform
2 precursor [Homo sapiens]
Length = 346
Score = 29.3 bits (64), Expect = 3.7
Identities = 19/59 (32%), Positives = 29/59 (49%)
Query: 9 SPVRLLLFLLLLLIALEIMVGGHSLCFNFTIKSLSRPGQPWCEAQVFLNKNLFLQYNSD 67
+P LLL L L + G HSL + T S G+P A +++ FL+++SD
Sbjct: 2 APRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
>gi|9625002 integrin, beta 6 [Homo sapiens]
Length = 788
Score = 29.3 bits (64), Expect = 3.7
Identities = 9/20 (45%), Positives = 17/20 (85%)
Query: 228 IILGAFILLVLMGIVLICVW 247
I+LG + ++L+G+VL+C+W
Sbjct: 711 IMLGVSLAILLIGVVLLCIW 730
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.136 0.448
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,367,979
Number of Sequences: 37866
Number of extensions: 443570
Number of successful extensions: 1192
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1155
Number of HSP's gapped (non-prelim): 35
length of query: 263
length of database: 18,247,518
effective HSP length: 100
effective length of query: 163
effective length of database: 14,460,918
effective search space: 2357129634
effective search space used: 2357129634
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.