Guide to the Human Genome
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Name: HFE Sequence: fasta or formatted (334aa) NCBI GI: 21040347
Description:

hemochromatosis protein isoform 6 precursor

Referenced in:

HLA and Related Proteins
Iron, Copper, and Arsenic Metabolism

Other entries for this name:
alt prot [242aa] hemochromatosis protein isoform 3 precursor
alt prot [256aa] hemochromatosis protein isoform 4 precursor
alt prot [260aa] hemochromatosis protein isoform 7 precursor
alt prot [246aa] hemochromatosis protein isoform 8 precursor
alt prot [325aa] hemochromatosis protein isoform 9 precursor
alt prot [168aa] hemochromatosis protein isoform 10 precursor
alt prot [76aa] hemochromatosis protein isoform 11 precursor
alt prot [348aa] hemochromatosis protein isoform 1 precursor
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.1         17           2
 C cysteine            1.5          5           1
 D aspartate           5.4         18           2
 E glutamate           6.9         23           2
 F phenylalanine       3.3         11           1
 G glycine             7.2         24           1
 H histidine           3.3         11           1
 I isoleucine          4.8         16           2
 K lysine              3.3         11           1
 L leucine            12.6         42           4
 M methionine          3.0         10           1
 N asparagine          2.1          7           1
 P proline             5.4         18           2
 Q glutamine           6.9         23           2
 R arginine            6.9         23           2
 S serine              5.4         18           2
 T threonine           4.5         15           2
 V valine              5.7         19           2
 W tryptophan          3.3         11           1
 Y tyrosine            3.6         12           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hemochromatosis protein isoform 6 precursor 
HFE                   0.987   hemochromatosis protein isoform 1 precursor 
HFE                   0.896   hemochromatosis protein isoform 9 precursor 
HFE                   0.656   hemochromatosis protein isoform 8 precursor 
HFE                   0.642   hemochromatosis protein isoform 7 precursor 
HFE                   0.364   hemochromatosis protein isoform 3 precursor 
HFE                   0.362   hemochromatosis protein isoform 10 precursor 
HFE                   0.362   hemochromatosis protein isoform 4 precursor 
MR1                   0.271   major histocompatibility complex, class I-related [Ho...
HLA-A                 0.259   major histocompatibility complex, class I, A precurs...
HLA-B                 0.255   major histocompatibility complex, class I, B precurs...
LOC652614             0.250   PREDICTED: similar to MHC class I antigen 
HLA-C                 0.241   major histocompatibility complex, class I, C precurs...
HLA-F                 0.240   major histocompatibility complex, class I, F isofor...
HLA-F                 0.240   major histocompatibility complex, class I, F isofor...
HLA-G                 0.240   major histocompatibility complex, class I, G precurso...
HLA-E                 0.237   major histocompatibility complex, class I, E precurs...
AZGP1                 0.235   alpha-2-glycoprotein 1, zinc 
MICB                  0.152   MHC class I polypeptide-related sequence B 
MICA                  0.142   MHC class I polypeptide-related sequence A 
FCGRT                 0.136   Fc fragment of IgG, receptor, transporter, alpha [H...
FCGRT                 0.136   Fc fragment of IgG, receptor, transporter, alpha [Hom...
HFE                   0.110   hemochromatosis protein isoform 11 precursor 
HLA-F                 0.100   major histocompatibility complex, class I, F isofor...
CD1D                  0.088   CD1D antigen precursor 
LOC100294318          0.079   PREDICTED: similar to major histocompatibility comp...
LOC100294318          0.077   PREDICTED: similar to major histocompatibility comp...
HLA-DQB1              0.075   major histocompatibility complex, class II, DQ beta...
HLA-DRB4              0.075   major histocompatibility complex, class II, DR beta ...
HLA-DRB4              0.075   PREDICTED: major histocompatibility complex, class ...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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