HFE 28828

Name: HFE	Sequence: fasta or formatted (348aa)		NCBI GI: 4504377
Description: hemochromatosis protein isoform 1 precursor		Referenced in: Major Disease Loci HLA and Related Proteins Iron, Copper, and Arsenic Metabolism Polymorphism
Other entries for this name: alt prot [242aa] hemochromatosis protein isoform 3 precursor alt prot [256aa] hemochromatosis protein isoform 4 precursor alt prot [334aa] hemochromatosis protein isoform 6 precursor alt prot [260aa] hemochromatosis protein isoform 7 precursor alt prot [246aa] hemochromatosis protein isoform 8 precursor alt prot [325aa] hemochromatosis protein isoform 9 precursor alt prot [168aa] hemochromatosis protein isoform 10 precursor alt prot [76aa] hemochromatosis protein isoform 11 precursor
Composition: Amino acid Percentage Count Longest homopolymer A alanine 4.9 17 2 C cysteine 1.4 5 1 D aspartate 5.2 18 2 E glutamate 6.6 23 2 F phenylalanine 3.2 11 1 G glycine 6.9 24 1 H histidine 3.7 13 2 I isoleucine 4.6 16 2 K lysine 3.4 12 1 L leucine 12.4 43 4 M methionine 2.9 10 1 N asparagine 2.0 7 1 P proline 5.7 20 2 Q glutamine 6.6 23 2 R arginine 6.6 23 2 S serine 5.7 20 2 T threonine 4.9 17 2 V valine 6.6 23 2 W tryptophan 3.2 11 1 Y tyrosine 3.4 12 2			Comparative genomics: Search single species RefSeq proteins at NCBI H. sapiens M. musculus D. rerio C. intestinalis S. purpuratus D. melanogaster C. elegans A. thaliana S. cerevisiae E. coli W3110 A. pernix K1 Search summary Figure data Additional searches of RefSeq proteins at NCBI All Eukaryotes Bacteria Archaea Viruses Primates Mammals Vertebrates
Related human proteins: Protein Relative score Description Self-match 1.000 hemochromatosis protein isoform 1 precursor HFE 0.947 hemochromatosis protein isoform 6 precursor HFE 0.914 hemochromatosis protein isoform 9 precursor HFE 0.670 hemochromatosis protein isoform 7 precursor HFE 0.617 hemochromatosis protein isoform 8 precursor HFE 0.389 hemochromatosis protein isoform 4 precursor HFE 0.386 hemochromatosis protein isoform 10 precursor HFE 0.352 hemochromatosis protein isoform 3 precursor MR1 0.283 major histocompatibility complex, class I-related [Ho... HLA-A 0.273 major histocompatibility complex, class I, A precurs... HLA-B 0.272 major histocompatibility complex, class I, B precurs... LOC652614 0.265 PREDICTED: similar to MHC class I antigen HLA-C 0.259 major histocompatibility complex, class I, C precurs... HLA-G 0.255 major histocompatibility complex, class I, G precurso... HLA-F 0.253 major histocompatibility complex, class I, F isofor... HLA-F 0.253 major histocompatibility complex, class I, F isofor... HLA-E 0.252 major histocompatibility complex, class I, E precurs... AZGP1 0.247 alpha-2-glycoprotein 1, zinc MICB 0.165 MHC class I polypeptide-related sequence B MICA 0.156 MHC class I polypeptide-related sequence A FCGRT 0.146 Fc fragment of IgG, receptor, transporter, alpha [H... FCGRT 0.146 Fc fragment of IgG, receptor, transporter, alpha [Hom... HFE 0.106 hemochromatosis protein isoform 11 precursor HLA-F 0.097 major histocompatibility complex, class I, F isofor... LOC100294318 0.090 PREDICTED: similar to major histocompatibility comp... CD1D 0.090 CD1D antigen precursor LOC100294318 0.090 PREDICTED: similar to major histocompatibility comp... HLA-DQB1 0.087 major histocompatibility complex, class II, DQ beta... LOC100133583 0.086 PREDICTED: similar to major histocompatibility comp... LOC100133583 0.080 PREDICTED: similar to major histocompatibility comp... Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.