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Search of human proteins with 110618224
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110618224 CD1A antigen precursor [Homo sapiens]
(327 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110618224 CD1A antigen precursor [Homo sapiens] 692 0.0
gi|4502645 CD1B antigen precursor [Homo sapiens] 394 e-110
gi|110618227 CD1C antigen precursor [Homo sapiens] 390 e-109
gi|110618240 CD1E antigen isoform a precursor [Homo sapiens] 357 1e-98
gi|110618230 CD1E antigen isoform b precursor [Homo sapiens] 357 1e-98
gi|4502649 CD1D antigen precursor [Homo sapiens] 341 6e-94
gi|110618232 CD1E antigen isoform c precursor [Homo sapiens] 296 1e-80
gi|110618234 CD1E antigen isoform d precursor [Homo sapiens] 259 2e-69
gi|110618236 CD1E antigen isoform e precursor [Homo sapiens] 184 7e-47
gi|110618238 CD1E antigen isoform f precursor [Homo sapiens] 124 9e-29
gi|4504417 major histocompatibility complex, class I-related [Ho... 103 2e-22
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 95 1e-19
gi|24797067 major histocompatibility complex, class I, A precurs... 92 6e-19
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 88 1e-17
gi|4504415 major histocompatibility complex, class I, G precurso... 87 2e-17
gi|62912479 major histocompatibility complex, class I, E precurs... 86 6e-17
gi|52630342 major histocompatibility complex, class I, C precurs... 83 4e-16
gi|149158702 major histocompatibility complex, class I, F isofor... 82 8e-16
gi|149158698 major histocompatibility complex, class I, F isofor... 82 8e-16
gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H... 81 1e-15
gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom... 81 1e-15
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 80 2e-15
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 80 2e-15
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 74 1e-13
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 73 4e-13
gi|17986001 major histocompatibility complex, class I, B precurs... 71 1e-12
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 67 3e-11
gi|24797076 major histocompatibility complex, class II, DP beta ... 57 2e-08
gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi... 56 5e-08
gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s... 55 9e-08
>gi|110618224 CD1A antigen precursor [Homo sapiens]
Length = 327
Score = 692 bits (1785), Expect = 0.0
Identities = 327/327 (100%), Positives = 327/327 (100%)
Query: 1 MLFLLLPLLAVLPGDGNADGLKEPLSFHVTWIASFYNHSWKQNLVSGWLSDLQTHTWDSN 60
MLFLLLPLLAVLPGDGNADGLKEPLSFHVTWIASFYNHSWKQNLVSGWLSDLQTHTWDSN
Sbjct: 1 MLFLLLPLLAVLPGDGNADGLKEPLSFHVTWIASFYNHSWKQNLVSGWLSDLQTHTWDSN 60
Query: 61 SSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGCE 120
SSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGCE
Sbjct: 61 SSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGCE 120
Query: 121 LHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLLS 180
LHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLLS
Sbjct: 121 LHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLLS 180
Query: 181 DTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMRG 240
DTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMRG
Sbjct: 181 DTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMRG 240
Query: 241 EQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHSSV 300
EQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHSSV
Sbjct: 241 EQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHSSV 300
Query: 301 GFIILAVIVPLLLLIGLALWFRKRCFC 327
GFIILAVIVPLLLLIGLALWFRKRCFC
Sbjct: 301 GFIILAVIVPLLLLIGLALWFRKRCFC 327
>gi|4502645 CD1B antigen precursor [Homo sapiens]
Length = 333
Score = 394 bits (1012), Expect = e-110
Identities = 198/326 (60%), Positives = 240/326 (73%), Gaps = 2/326 (0%)
Query: 1 MLFLLLPLLAVL-PGDGNADGLKEPLSFHVTWIASFYNHSWKQNLVSGWLSDLQTHTWDS 59
ML L LLAVL PG + + P SFHV +SF N +W Q SGWL DLQ H WDS
Sbjct: 1 MLLLPFQLLAVLFPGGNSEHAFQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDS 60
Query: 60 NSSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGC 119
+S T +FL PWS+GNFS++E ELE +FR+ ++ +A + Q +YPFEIQ GC
Sbjct: 61 DSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGC 120
Query: 120 ELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLL 179
ELHSG SFL+ A G DF+S +N S +P P G+ A+ FC ++ Q Q + LL
Sbjct: 121 ELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILL 180
Query: 180 SDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMR 239
+TCPR++LG+L+AGKA LQRQVKPEAWLS GPSPGPG LQLVCHVSGFYPKPVWVMWMR
Sbjct: 181 YETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMR 240
Query: 240 GEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHSS 299
GEQEQQGTQ GDILP+A+ TWYLRATL+VA GEAA LSCRVKHSSLEGQDI+LYW + +S
Sbjct: 241 GEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRNPTS 300
Query: 300 VGFIILAVIVP-LLLLIGLALWFRKR 324
+G I+LA+IVP LLLL+ LALW+ +R
Sbjct: 301 IGSIVLAIIVPSLLLLLCLALWYMRR 326
>gi|110618227 CD1C antigen precursor [Homo sapiens]
Length = 333
Score = 390 bits (1003), Expect = e-109
Identities = 192/327 (58%), Positives = 233/327 (71%), Gaps = 2/327 (0%)
Query: 1 MLFLLLPLLAVL-PGDGNADGLKEPLSFHVTWIASFYNHSWKQNLVSGWLSDLQTHTWDS 59
MLFL LLA+L PG NAD +E +SFHV I SF N SW + SGWL +LQTH WDS
Sbjct: 1 MLFLQFLLLALLLPGGDNADASQEHVSFHVIQIFSFVNQSWARGQGSGWLDELQTHGWDS 60
Query: 60 NSSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGC 119
S TI+FL WS+GNFSNEE +LE LFR I+ +A + +YPFE+QV GC
Sbjct: 61 ESGTIIFLHNWSKGNFSNEELSDLELLFRFYLFGLTREIQDHASQDYSKYPFEVQVKAGC 120
Query: 120 ELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLN-QNQHENDITHNL 178
ELHSGK F Q+A+ G D +SFQN +W+P P G++A+ C +LN Q + + +NL
Sbjct: 121 ELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVCHLLNHQYEGVTETVYNL 180
Query: 179 LSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWM 238
+ TCPRF+LGLLDAGK ++ RQV+PEAWLS PS G G L LVCH SGFYPKPVWV WM
Sbjct: 181 IRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFYPKPVWVTWM 240
Query: 239 RGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHS 298
R EQEQ GT+ GDILP+ADGTWYL+ LEVA+ E A LSCRV+HSSL GQDI+LYW HH
Sbjct: 241 RNEQEQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGGQDIILYWGHHF 300
Query: 299 SVGFIILAVIVPLLLLIGLALWFRKRC 325
S+ +I L VIVPL++LI L LWF+K C
Sbjct: 301 SMNWIALVVIVPLVILIVLVLWFKKHC 327
>gi|110618240 CD1E antigen isoform a precursor [Homo sapiens]
Length = 388
Score = 357 bits (915), Expect = 1e-98
Identities = 181/325 (55%), Positives = 230/325 (70%), Gaps = 14/325 (4%)
Query: 1 MLFLLLPLLAVLPGDGNAD---------GLKEPLSFHVTWIASFYNHSWKQNLVSGWLSD 51
+LFLL L PG+ A +E LSF + +SF NHSW + SGWL D
Sbjct: 3 LLFLLFEGLCC-PGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGD 61
Query: 52 LQTHTWDSNSSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPF 111
LQTH WD+ TI FL PWS GNFS +E K L++LF++ + ++ A + Q EYPF
Sbjct: 62 LQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPF 121
Query: 112 EIQVTGGCELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHE 171
EIQ+ GC +++ ++ FL +AYQGSDF+SFQ SW P P AG A++ CKVLN+
Sbjct: 122 EIQILAGCRMNAPQI---FLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDI 178
Query: 172 NDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPK 231
+I +LL TCPRF+ GL++AG++ L+R+VKPEAWLS GPSPGPG LQLVCHVSGFYPK
Sbjct: 179 KEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPK 238
Query: 232 PVWVMWMRGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIV 291
PVWVMWMRGEQEQ+GTQRGD+LP+AD TWYLRATL+VAAGEAA LSCRVKHSSL G D++
Sbjct: 239 PVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLI 298
Query: 292 LYWEHHSSVGFII-LAVIVPLLLLI 315
++W +S +I L VIV L++L+
Sbjct: 299 IHWGGYSIFLILICLTVIVTLVILV 323
>gi|110618230 CD1E antigen isoform b precursor [Homo sapiens]
Length = 376
Score = 357 bits (915), Expect = 1e-98
Identities = 181/325 (55%), Positives = 230/325 (70%), Gaps = 14/325 (4%)
Query: 1 MLFLLLPLLAVLPGDGNAD---------GLKEPLSFHVTWIASFYNHSWKQNLVSGWLSD 51
+LFLL L PG+ A +E LSF + +SF NHSW + SGWL D
Sbjct: 3 LLFLLFEGLCC-PGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGD 61
Query: 52 LQTHTWDSNSSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPF 111
LQTH WD+ TI FL PWS GNFS +E K L++LF++ + ++ A + Q EYPF
Sbjct: 62 LQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPF 121
Query: 112 EIQVTGGCELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHE 171
EIQ+ GC +++ ++ FL +AYQGSDF+SFQ SW P P AG A++ CKVLN+
Sbjct: 122 EIQILAGCRMNAPQI---FLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDI 178
Query: 172 NDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPK 231
+I +LL TCPRF+ GL++AG++ L+R+VKPEAWLS GPSPGPG LQLVCHVSGFYPK
Sbjct: 179 KEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPK 238
Query: 232 PVWVMWMRGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIV 291
PVWVMWMRGEQEQ+GTQRGD+LP+AD TWYLRATL+VAAGEAA LSCRVKHSSL G D++
Sbjct: 239 PVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLI 298
Query: 292 LYWEHHSSVGFII-LAVIVPLLLLI 315
++W +S +I L VIV L++L+
Sbjct: 299 IHWGGYSIFLILICLTVIVTLVILV 323
>gi|4502649 CD1D antigen precursor [Homo sapiens]
Length = 335
Score = 341 bits (874), Expect = 6e-94
Identities = 170/327 (51%), Positives = 225/327 (68%), Gaps = 5/327 (1%)
Query: 1 MLFLLLPLLAVLPGDGNADGLKEPLSFHVTWIASFYNHSWKQNLVSGWLSDLQTHTWDSN 60
+LFLLL A+L G+A+ + I+SF N SW + WL +LQTH+W ++
Sbjct: 4 LLFLLL--WALLQAWGSAEVPQRLFPLRCLQISSFANSSWTRTDGLAWLGELQTHSWSND 61
Query: 61 SSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGCE 120
S T+ L PWS+G FS+++W+ L+ +FR+ ++ +A L+ YP E+QV+ GCE
Sbjct: 62 SDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLELQVSAGCE 121
Query: 121 LHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLLS 180
+H G S +F +A+QG D +SFQ SW P A +VLNQ++ + LL+
Sbjct: 122 VHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKWTRETVQWLLN 181
Query: 181 DTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMRG 240
TCP+F+ GLL++GK+ L++QVKP+AWLS GPSPGPG L LVCHVSGFYPKPVWV WMRG
Sbjct: 182 GTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWVKWMRG 241
Query: 241 EQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYW-EHHSS 299
EQEQQGTQ GDILP+AD TWYLRATL+V AGEAA LSCRVKHSSLEGQDIVLYW ++S
Sbjct: 242 EQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVLYWGGSYTS 301
Query: 300 VGFIILAVIVPL--LLLIGLALWFRKR 324
+G I LAV+ L LL++G F+++
Sbjct: 302 MGLIALAVLACLLFLLIVGFTSRFKRQ 328
>gi|110618232 CD1E antigen isoform c precursor [Homo sapiens]
Length = 290
Score = 296 bits (759), Expect = 1e-80
Identities = 147/271 (54%), Positives = 188/271 (69%), Gaps = 13/271 (4%)
Query: 1 MLFLLLPLLAVLPGDGNAD---------GLKEPLSFHVTWIASFYNHSWKQNLVSGWLSD 51
+LFLL L PG+ A +E LSF + +SF NHSW + SGWL D
Sbjct: 3 LLFLLFEGLCC-PGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGD 61
Query: 52 LQTHTWDSNSSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPF 111
LQTH WD+ TI FL PWS GNFS +E K L++LF++ + ++ A + Q EYPF
Sbjct: 62 LQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPF 121
Query: 112 EIQVTGGCELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHE 171
EIQ+ GC +++ ++ FL +AYQGSDF+SFQ SW P P AG A++ CKVLN+
Sbjct: 122 EIQILAGCRMNAPQI---FLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDI 178
Query: 172 NDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPK 231
+I +LL TCPRF+ GL++AG++ L+R+VKPEAWLS GPSPGPG LQLVCHVSGFYPK
Sbjct: 179 KEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPK 238
Query: 232 PVWVMWMRGEQEQQGTQRGDILPSADGTWYL 262
PVWVMWMRGEQEQ+GTQRGD+LP+AD TW++
Sbjct: 239 PVWVMWMRGEQEQRGTQRGDVLPNADETWWI 269
>gi|110618234 CD1E antigen isoform d precursor [Homo sapiens]
Length = 321
Score = 259 bits (662), Expect = 2e-69
Identities = 131/249 (52%), Positives = 167/249 (67%), Gaps = 13/249 (5%)
Query: 1 MLFLLLPLLAVLPGDGNAD---------GLKEPLSFHVTWIASFYNHSWKQNLVSGWLSD 51
+LFLL L PG+ A +E LSF + +SF NHSW + SGWL D
Sbjct: 3 LLFLLFEGLCC-PGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGD 61
Query: 52 LQTHTWDSNSSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPF 111
LQTH WD+ TI FL PWS GNFS +E K L++LF++ + ++ A + Q EYPF
Sbjct: 62 LQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPF 121
Query: 112 EIQVTGGCELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHE 171
EIQ+ GC +++ ++ FL +AYQGSDF+SFQ SW P P AG A++ CKVLN+
Sbjct: 122 EIQILAGCRMNAPQI---FLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDI 178
Query: 172 NDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPK 231
+I +LL TCPRF+ GL++AG++ L+R+VKPEAWLS GPSPGPG LQLVCHVSGFYPK
Sbjct: 179 KEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPK 238
Query: 232 PVWVMWMRG 240
PVWVMWMRG
Sbjct: 239 PVWVMWMRG 247
>gi|110618236 CD1E antigen isoform e precursor [Homo sapiens]
Length = 187
Score = 184 bits (468), Expect = 7e-47
Identities = 87/115 (75%), Positives = 100/115 (86%), Gaps = 1/115 (0%)
Query: 202 VKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQRGDILPSADGTWY 261
VKPEAWLS GPSPGPG LQLVCHVSGFYPKPVWVMWMRGEQEQ+GTQRGD+LP+AD TWY
Sbjct: 20 VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY 79
Query: 262 LRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHSSVGFII-LAVIVPLLLLI 315
LRATL+VAAGEAA LSCRVKHSSL G D++++W +S +I L VIV L++L+
Sbjct: 80 LRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILV 134
>gi|110618238 CD1E antigen isoform f precursor [Homo sapiens]
Length = 101
Score = 124 bits (312), Expect = 9e-29
Identities = 53/61 (86%), Positives = 58/61 (95%)
Query: 202 VKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQRGDILPSADGTWY 261
VKPEAWLS GPSPGPG LQLVCHVSGFYPKPVWVMWMRGEQEQ+GTQRGD+LP+AD TW+
Sbjct: 20 VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWW 79
Query: 262 L 262
+
Sbjct: 80 I 80
>gi|4504417 major histocompatibility complex, class I-related [Homo
sapiens]
Length = 341
Score = 103 bits (257), Expect = 2e-22
Identities = 93/334 (27%), Positives = 145/334 (43%), Gaps = 22/334 (6%)
Query: 1 MLFLLLPLLAVLPGDGNADGLKEPLSFHVTWIASFYNHSWKQNLVSGWLSDLQTHTWDSN 60
++ LLPL+ VL ++D L + ++ H + + G++ T+DS
Sbjct: 4 LMAFLLPLIIVLMVK-HSDSRTHSLRYFRLGVSDPI-HGVPEFISVGYVDSHPITTYDSV 61
Query: 61 SSTIVFLCPWSRGNFSNEEWKELETLFR----IRTIRSFEGIRRYAHELQFEYPFEIQVT 116
+ PW N + + W+ L R + + R Y H Y I
Sbjct: 62 TRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMI--- 118
Query: 117 GGCELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITH 176
GCEL + FLQ AY G DF+ F N L + N+A + NQHE
Sbjct: 119 -GCELLEDGSTTGFLQYAYDGQDFLIF-NKDTLSWLAVDNVAHTIKQAWEANQHELLYQK 176
Query: 177 NLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVM 236
N L + C ++ L+ GK LQR P ++ + PG L C GFYP +++
Sbjct: 177 NWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKET-FPGVTALFCKAHGFYPPEIYMT 235
Query: 237 WMR-GEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWE 295
WM+ GE+ Q GDILPS DGT+ A++E+ + SC V+H G +VL
Sbjct: 236 WMKNGEEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHC---GVHMVLQVP 292
Query: 296 HHSSVGFIIL------AVIVPLLLLIGLALWFRK 323
S +++ V+V +L +G+ +W R+
Sbjct: 293 QESETIPLVMKAVSGSIVLVIVLAGVGVLVWRRR 326
>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
sapiens]
Length = 366
Score = 94.7 bits (234), Expect = 1e-19
Identities = 82/293 (27%), Positives = 134/293 (45%), Gaps = 25/293 (8%)
Query: 47 GWLSDLQTHTWDSNSSTIVF--LCPWSRGNFSNEEWKELETLFRIRTIRSFE----GIRR 100
G++ D Q +DS+S+ PW E W E + + T +SF +R
Sbjct: 63 GYVDDTQFVRFDSDSANPREEPRAPWMEQE-GPEYWDEQTRIVK-DTAQSFRVGLNTLRG 120
Query: 101 YAHELQFEYPFEIQVTGGCELH-SGKVSGSFLQLAYQGSDFVSFQNN--SWLPYPVAGNM 157
Y ++ + +Q+ GC++ G+ F+Q AY G D+++ + SW A +
Sbjct: 121 YYNQSEAG-SHTLQLMYGCDVGPDGRFLRGFMQDAYDGRDYIALNEDLRSWTAADTAAQI 179
Query: 158 AKHFCKVLNQNQHENDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPG 217
K + + + N L C + L+ GK L R P+A ++H P
Sbjct: 180 TKRKREAAGAAERQR----NYLEGRCVEGLRRYLETGKDALLRADPPKAHVTHHPI-SER 234
Query: 218 HLQLVCHVSGFYPKPVWVMWMR-GEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADL 276
+ L C GFYP+ + + W R GE + Q + + PS DGT+ A L V +GE
Sbjct: 235 EVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDGTFQKWAALVVPSGEEQRY 294
Query: 277 SCRVKHSSLEGQDIVLYWEHHSSVGFIILAVIVPLLLLI-----GLALWFRKR 324
+CRV+H L+ + + L WE F+I+ +IV L+LL+ G +W +KR
Sbjct: 295 TCRVQHEGLQ-EPLTLRWE-PPQTSFLIMGIIVGLVLLVVALVAGAVIWRKKR 345
>gi|24797067 major histocompatibility complex, class I, A precursor
[Homo sapiens]
Length = 365
Score = 92.0 bits (227), Expect = 6e-19
Identities = 67/223 (30%), Positives = 103/223 (46%), Gaps = 18/223 (8%)
Query: 113 IQVTGGCELHS-GKVSGSFLQLAYQGSDFVSFQNN--SWLPYPVAGNMAKHFCKVLNQNQ 169
IQ+ GC++ S G+ + Q AY G D+++ + SW A +MA K +
Sbjct: 119 IQIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSW----TAADMAAQITKRKWEAA 174
Query: 170 HENDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFY 229
HE + L TC ++ L+ GK LQR P+ ++H P L C GFY
Sbjct: 175 HEAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPI-SDHEATLRCWALGFY 233
Query: 230 PKPVWVMWMR-GEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQ 288
P + + W R GE + Q T+ + P+ DGT+ A + V +GE +C V+H L +
Sbjct: 234 PAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLP-K 292
Query: 289 DIVLYWEHHSSVGFIILAVIVPLLLL--------IGLALWFRK 323
+ L WE S I+ +I L+LL + +W RK
Sbjct: 293 PLTLRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRK 335
>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
Length = 298
Score = 87.8 bits (216), Expect = 1e-17
Identities = 82/306 (26%), Positives = 133/306 (43%), Gaps = 28/306 (9%)
Query: 1 MLFLLLPLLAVLPGDGNADG------LKEPLSFHVTWIASFYNHSWKQNLVSGWLSDLQT 54
+L LLL L +P + N DG + LS HV + +F G L+DLQ
Sbjct: 8 LLSLLLLLGPAVPQE-NQDGRYSLTYIYTGLSKHVEDVPAFQ--------ALGSLNDLQF 58
Query: 55 HTWDSNSSTIVFLCPWSRGNFSNEEWKELETLFRIRT---IRSFEGIRRYAHELQFEYPF 111
++S + W + E+WK+ L + R + + + I Y ++ +
Sbjct: 59 FRYNSKDRKSQPMGLWRQVE-GMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHV- 116
Query: 112 EIQVTGGCELHSGKVSGSFLQLAYQGSDFVSFQNN--SWLPYPVAGNMAKHFCKVLNQNQ 169
+Q GCE+ + + SG+F + Y G D++ F +W+P+ A + K +
Sbjct: 117 -LQGRFGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYV 175
Query: 170 HENDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFY 229
L + CP + L K L RQ P ++ +PG +L C FY
Sbjct: 176 QR---AKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKK-KLKCLAYDFY 231
Query: 230 PKPVWVMWMRGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQD 289
P + V W R + Q+ RGD+L + +GT+ + V + A SC V+HSSL Q
Sbjct: 232 PGKIDVHWTRAGEVQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSL-AQP 290
Query: 290 IVLYWE 295
+V+ WE
Sbjct: 291 LVVPWE 296
>gi|4504415 major histocompatibility complex, class I, G precursor
[Homo sapiens]
Length = 338
Score = 87.0 bits (214), Expect = 2e-17
Identities = 77/297 (25%), Positives = 133/297 (44%), Gaps = 25/297 (8%)
Query: 44 LVSGWLSDLQTHTWDSNSST--IVFLCPWSRGNFSNEEWKE--LETLFRIRTIR-SFEGI 98
+ G++ D Q +DS+S+ + PW E W+E T +T R + + +
Sbjct: 47 IAMGYVDDTQFVRFDSDSACPRMEPRAPWVEQE-GPEYWEEETRNTKAHAQTDRMNLQTL 105
Query: 99 RRYAHELQFEYPFEIQVTGGCELHS-GKVSGSFLQLAYQGSDFVSFQNN--SWLPYPVAG 155
R Y ++ + +Q GC+L S G++ + Q AY G D+++ + SW A
Sbjct: 106 RGYYNQSEAS-SHTLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAA 164
Query: 156 NMAKHFCKVLNQNQHENDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPG 215
++K C+ N + L TC ++ L+ GK LQR P+ ++H P
Sbjct: 165 QISKRKCEAANVAEQRRAY----LEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPV-F 219
Query: 216 PGHLQLVCHVSGFYPKPVWVMWMR-GEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAA 274
L C GFYP + + W R GE + Q + + P+ DGT+ A + V +GE
Sbjct: 220 DYEATLRCWALGFYPAEIILTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQ 279
Query: 275 DLSCRVKHSSLEGQDIVLYWEHHSSVGFIILAVIVPLLLL--------IGLALWFRK 323
+C V+H L + ++L W+ S I+ ++ L++L + LW +K
Sbjct: 280 RYTCHVQHEGLP-EPLMLRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKK 335
>gi|62912479 major histocompatibility complex, class I, E precursor
[Homo sapiens]
Length = 358
Score = 85.5 bits (210), Expect = 6e-17
Identities = 83/321 (25%), Positives = 141/321 (43%), Gaps = 42/321 (13%)
Query: 21 LKEPLSFHVTWIASF---YNHS-------WKQNLVS-GWLSDLQTHTWDSNSST--IVFL 67
L E L+ TW S Y H+ + +S G++ D Q +D+++++ +V
Sbjct: 10 LSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPR 69
Query: 68 CPWSRGNFSNEEW-------KELETLFRI--RTIRSFEGIRRY-AHELQFEYPFEIQVTG 117
PW S E W ++ +FR+ RT+R + +H LQ+ +
Sbjct: 70 APWMEQEGS-EYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMH-------- 120
Query: 118 GCELH-SGKVSGSFLQLAYQGSDFVSFQNN--SWLPYPVAGNMAKHFCKVLNQNQHENDI 174
GCEL G+ + Q AY G D+++ + SW A +++ ++ +H+
Sbjct: 121 GCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAY 180
Query: 175 THNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVW 234
L DTC ++ L+ GK L P+ ++H P L C GFYP +
Sbjct: 181 ----LEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPI-SDHEATLRCWALGFYPAEIT 235
Query: 235 VMWMR-GEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLY 293
+ W + GE Q T+ + P+ DGT+ A + V +GE +C V+H L + + L
Sbjct: 236 LTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLP-EPVTLR 294
Query: 294 WEHHSSVGFIILAVIVPLLLL 314
W+ S I+ +I L+LL
Sbjct: 295 WKPASQPTIPIVGIIAGLVLL 315
>gi|52630342 major histocompatibility complex, class I, C precursor
[Homo sapiens]
Length = 366
Score = 82.8 bits (203), Expect = 4e-16
Identities = 59/230 (25%), Positives = 105/230 (45%), Gaps = 11/230 (4%)
Query: 94 SFEGIRRYAHELQFEYPFEIQVTGGCELH-SGKVSGSFLQLAYQGSDFVSFQNN--SWLP 150
S +R Y ++ + + +Q GC+L G++ + Q AY G D+++ + SW
Sbjct: 101 SLRNLRGYYNQSE-DGSHTLQRMSGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTA 159
Query: 151 YPVAGNMAKHFCKVLNQNQHENDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSH 210
A + + + + L TC ++ L+ GK LQR P+ ++H
Sbjct: 160 ADTAAQITQRKLEAARAAEQ----LRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTH 215
Query: 211 GPSPGPGHLQLVCHVSGFYPKPVWVMWMR-GEQEQQGTQRGDILPSADGTWYLRATLEVA 269
P L C GFYP + + W R GE + Q T+ + P+ DGT+ A + V
Sbjct: 216 HPL-SDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP 274
Query: 270 AGEAADLSCRVKHSSLEGQDIVLYWEHHSSVGFIILAVIVPLLLLIGLAL 319
+G+ +C ++H L+ + + L WE S I+ ++ L +L+ LA+
Sbjct: 275 SGQEQRYTCHMQHEGLQ-EPLTLSWEPSSQPTIPIMGIVAGLAVLVVLAV 323
>gi|149158702 major histocompatibility complex, class I, F isoform 1
precursor [Homo sapiens]
Length = 442
Score = 81.6 bits (200), Expect = 8e-16
Identities = 56/206 (27%), Positives = 93/206 (45%), Gaps = 10/206 (4%)
Query: 113 IQVTGGCELH-SGKVSGSFLQLAYQGSDFVSFQNN--SWLPYPVAGNMAKHFCKVLNQNQ 169
+Q GC++ G++ + Q AY G D++S + SW + + F + +
Sbjct: 116 LQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEA----E 171
Query: 170 HENDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFY 229
+ L C + L+ GK LQR P+A ++H P L C GFY
Sbjct: 172 EYAEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPI-SDHEATLRCWALGFY 230
Query: 230 PKPVWVMWMR-GEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQ 288
P + + W R GE++ Q T+ + P+ DGT+ A + V GE +C V+H L Q
Sbjct: 231 PAEITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLP-Q 289
Query: 289 DIVLYWEHHSSVGFIILAVIVPLLLL 314
++L WE I+ ++ L++L
Sbjct: 290 PLILRWEQSPQPTIPIVGIVAGLVVL 315
>gi|149158698 major histocompatibility complex, class I, F isoform 2
precursor [Homo sapiens]
Length = 346
Score = 81.6 bits (200), Expect = 8e-16
Identities = 56/206 (27%), Positives = 93/206 (45%), Gaps = 10/206 (4%)
Query: 113 IQVTGGCELH-SGKVSGSFLQLAYQGSDFVSFQNN--SWLPYPVAGNMAKHFCKVLNQNQ 169
+Q GC++ G++ + Q AY G D++S + SW + + F + +
Sbjct: 116 LQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEA----E 171
Query: 170 HENDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFY 229
+ L C + L+ GK LQR P+A ++H P L C GFY
Sbjct: 172 EYAEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPI-SDHEATLRCWALGFY 230
Query: 230 PKPVWVMWMR-GEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQ 288
P + + W R GE++ Q T+ + P+ DGT+ A + V GE +C V+H L Q
Sbjct: 231 PAEITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLP-Q 289
Query: 289 DIVLYWEHHSSVGFIILAVIVPLLLL 314
++L WE I+ ++ L++L
Sbjct: 290 PLILRWEQSPQPTIPIVGIVAGLVVL 315
>gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 81.3 bits (199), Expect = 1e-15
Identities = 84/331 (25%), Positives = 146/331 (44%), Gaps = 33/331 (9%)
Query: 8 LLAVLPGDGNADGLKEPLSFHVTWIASFYNHS---WKQNLVSGWLSDLQTHTWDSNSSTI 64
LL +LPG A+ L +H+T ++S + W VSGWL Q +++S
Sbjct: 14 LLFLLPGSLGAESHLS-LLYHLTAVSSPAPGTPAFW----VSGWLGPQQYLSYNSLRGEA 68
Query: 65 VFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGCELHSG 124
W N + W++ T RI+ E + L + P+ +Q GCEL
Sbjct: 69 EPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKA----LGGKGPYTLQGLLGCELGPD 124
Query: 125 KVSGSFLQLAYQGSDFVSF--QNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHN----L 178
S + A G +F++F + +W G+ + ++Q + D N
Sbjct: 125 NTSVPTAKFALNGEEFMNFDLKQGTW-----GGDWPEALA--ISQRWQQQDKAANKELTF 177
Query: 179 LSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWM 238
L +CP + L+ G+ +L+ + P L PS PG L C FYP + + ++
Sbjct: 178 LLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPS-SPGFSVLTCSAFSFYPPELQLRFL 236
Query: 239 RGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHS 298
R GT +GD P++DG+++ ++L V +G+ C V+H+ L Q + + E +
Sbjct: 237 RNGLAA-GTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGL-AQPLRVELESPA 294
Query: 299 SVGFIILAVIVPLLLLI-----GLALWFRKR 324
+++ +++ +LLL G LW R R
Sbjct: 295 KSSVLVVGIVIGVLLLTAAAVGGALLWRRMR 325
>gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 81.3 bits (199), Expect = 1e-15
Identities = 84/331 (25%), Positives = 146/331 (44%), Gaps = 33/331 (9%)
Query: 8 LLAVLPGDGNADGLKEPLSFHVTWIASFYNHS---WKQNLVSGWLSDLQTHTWDSNSSTI 64
LL +LPG A+ L +H+T ++S + W VSGWL Q +++S
Sbjct: 14 LLFLLPGSLGAESHLS-LLYHLTAVSSPAPGTPAFW----VSGWLGPQQYLSYNSLRGEA 68
Query: 65 VFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGCELHSG 124
W N + W++ T RI+ E + L + P+ +Q GCEL
Sbjct: 69 EPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKA----LGGKGPYTLQGLLGCELGPD 124
Query: 125 KVSGSFLQLAYQGSDFVSF--QNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHN----L 178
S + A G +F++F + +W G+ + ++Q + D N
Sbjct: 125 NTSVPTAKFALNGEEFMNFDLKQGTW-----GGDWPEALA--ISQRWQQQDKAANKELTF 177
Query: 179 LSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWM 238
L +CP + L+ G+ +L+ + P L PS PG L C FYP + + ++
Sbjct: 178 LLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPS-SPGFSVLTCSAFSFYPPELQLRFL 236
Query: 239 RGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHS 298
R GT +GD P++DG+++ ++L V +G+ C V+H+ L Q + + E +
Sbjct: 237 RNGLAA-GTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGL-AQPLRVELESPA 294
Query: 299 SVGFIILAVIVPLLLLI-----GLALWFRKR 324
+++ +++ +LLL G LW R R
Sbjct: 295 KSSVLVVGIVIGVLLLTAAAVGGALLWRRMR 325
>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
sapiens]
Length = 325
Score = 80.5 bits (197), Expect = 2e-15
Identities = 71/291 (24%), Positives = 128/291 (43%), Gaps = 22/291 (7%)
Query: 47 GWLSDLQTHTWDSNSSTIVFLCPWSRGNFSNEEWKELETLFR----IRTIRSFEGIRRYA 102
G++ D +D S + PW S++ W +L + + T+ + + +
Sbjct: 28 GYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHN 87
Query: 103 HELQFEYPFEIQVTGGCELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFC 162
H + +QV GCE+ + + + Y G D + F ++ L + A A +
Sbjct: 88 HSKESH---TLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDT-LDWRAAEPRA--WP 141
Query: 163 KVLNQNQHENDITHN--LLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQ 220
L +H+ N L CP + LL+ G+ L +QV P ++H + L+
Sbjct: 142 TKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLR 201
Query: 221 LVCHVSGFYPKPVWVMWMRGEQEQQGTQ--RGDILPSADGTWYLRATLEVAAGEAADLSC 278
C +YP+ + + W++ +Q + D+LP+ DGT+ TL V GE +C
Sbjct: 202 --CRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 259
Query: 279 RVKHSSLEGQDIVLYWEHHSSVGFII-----LAVIVPLLLLIGLALWFRKR 324
+V+H L+ Q +++ WE S +I +AV V +L + L + RKR
Sbjct: 260 QVEHPGLD-QPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 309
>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
sapiens]
Length = 348
Score = 80.5 bits (197), Expect = 2e-15
Identities = 71/291 (24%), Positives = 128/291 (43%), Gaps = 22/291 (7%)
Query: 47 GWLSDLQTHTWDSNSSTIVFLCPWSRGNFSNEEWKELETLFR----IRTIRSFEGIRRYA 102
G++ D +D S + PW S++ W +L + + T+ + + +
Sbjct: 51 GYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHN 110
Query: 103 HELQFEYPFEIQVTGGCELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFC 162
H + +QV GCE+ + + + Y G D + F ++ L + A A +
Sbjct: 111 HSKESH---TLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDT-LDWRAAEPRA--WP 164
Query: 163 KVLNQNQHENDITHN--LLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQ 220
L +H+ N L CP + LL+ G+ L +QV P ++H + L+
Sbjct: 165 TKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLR 224
Query: 221 LVCHVSGFYPKPVWVMWMRGEQEQQGTQ--RGDILPSADGTWYLRATLEVAAGEAADLSC 278
C +YP+ + + W++ +Q + D+LP+ DGT+ TL V GE +C
Sbjct: 225 --CRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 282
Query: 279 RVKHSSLEGQDIVLYWEHHSSVGFII-----LAVIVPLLLLIGLALWFRKR 324
+V+H L+ Q +++ WE S +I +AV V +L + L + RKR
Sbjct: 283 QVEHPGLD-QPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 332
>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
sapiens]
Length = 260
Score = 74.3 bits (181), Expect = 1e-13
Identities = 60/221 (27%), Positives = 103/221 (46%), Gaps = 15/221 (6%)
Query: 113 IQVTGGCELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHEN 172
+QV GCE+ + + + Y G D + F ++ L + A A + L +H+
Sbjct: 30 LQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDT-LDWRAAEPRA--WPTKLEWERHKI 86
Query: 173 DITHN--LLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYP 230
N L CP + LL+ G+ L +QV P ++H + L+ C +YP
Sbjct: 87 RARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLR--CRALNYYP 144
Query: 231 KPVWVMWMRGEQEQQGTQ--RGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQ 288
+ + + W++ +Q + D+LP+ DGT+ TL V GE +C+V+H L+ Q
Sbjct: 145 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLD-Q 203
Query: 289 DIVLYWEHHSSVGFII-----LAVIVPLLLLIGLALWFRKR 324
+++ WE S +I +AV V +L + L + RKR
Sbjct: 204 PLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 244
>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
sapiens]
Length = 334
Score = 72.8 bits (177), Expect = 4e-13
Identities = 69/291 (23%), Positives = 122/291 (41%), Gaps = 36/291 (12%)
Query: 47 GWLSDLQTHTWDSNSSTIVFLCPWSRGNFSNEEWKELETLFR----IRTIRSFEGIRRYA 102
G++ D +D S + PW S++ W +L + + T+ + + +
Sbjct: 51 GYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHN 110
Query: 103 HELQFEYPFEIQVTGGCELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFC 162
H + +QV GCE+ + + + Y G D + F ++ L + A A +
Sbjct: 111 HSKESH---TLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDT-LDWRAAEPRA--WP 164
Query: 163 KVLNQNQHENDITHN--LLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQ 220
L +H+ N L CP + LL+ G+ L +QV
Sbjct: 165 TKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVTT---------------- 208
Query: 221 LVCHVSGFYPKPVWVMWMRGEQEQQGTQ--RGDILPSADGTWYLRATLEVAAGEAADLSC 278
L C +YP+ + + W++ +Q + D+LP+ DGT+ TL V GE +C
Sbjct: 209 LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 268
Query: 279 RVKHSSLEGQDIVLYWEHHSSVGFII-----LAVIVPLLLLIGLALWFRKR 324
+V+H L+ Q +++ WE S +I +AV V +L + L + RKR
Sbjct: 269 QVEHPGLD-QPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 318
>gi|17986001 major histocompatibility complex, class I, B precursor
[Homo sapiens]
Length = 362
Score = 70.9 bits (172), Expect = 1e-12
Identities = 66/284 (23%), Positives = 116/284 (40%), Gaps = 31/284 (10%)
Query: 47 GWLSDLQTHTWDSNSSTIVF--LCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRY--- 101
G++ D Q +DS++++ PW E W +++ + E +R
Sbjct: 50 GYVDDTQFVRFDSDAASPREEPRAPWIEQE-GPEYWDRNTQIYKAQAQTDRESLRNLRGY 108
Query: 102 -------AHELQFEYPFEIQVTGGCELH-SGKVSGSFLQLAYQGSDFVSFQNN--SWLPY 151
+H LQ Y GC++ G++ Q AY G D+++ + SW
Sbjct: 109 YNQSEAGSHTLQSMY--------GCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAA 160
Query: 152 PVAGNMAKHFCKVLNQNQHENDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHG 211
A + + + + + L C ++ L+ GK L+R P+ ++H
Sbjct: 161 DTAAQITQRKWEAAREAEQRRAY----LEGECVEWLRRYLENGKDKLERADPPKTHVTHH 216
Query: 212 PSPGPGHLQLVCHVSGFYPKPVWVMWMR-GEQEQQGTQRGDILPSADGTWYLRATLEVAA 270
P L C GFYP + + W R GE + Q T+ + P+ D T+ A + V +
Sbjct: 217 PI-SDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPS 275
Query: 271 GEAADLSCRVKHSSLEGQDIVLYWEHHSSVGFIILAVIVPLLLL 314
GE +C V+H L + + L WE S I+ ++ L +L
Sbjct: 276 GEEQRYTCHVQHEGLP-KPLTLRWEPSSQSTVPIVGIVAGLAVL 318
>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
sapiens]
Length = 246
Score = 66.6 bits (161), Expect = 3e-11
Identities = 58/221 (26%), Positives = 97/221 (43%), Gaps = 29/221 (13%)
Query: 113 IQVTGGCELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHEN 172
+QV GCE+ + + + Y G D + F ++ L + A A + L +H+
Sbjct: 30 LQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDT-LDWRAAEPRA--WPTKLEWERHKI 86
Query: 173 DITHN--LLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYP 230
N L CP + LL+ G+ L +QV L C +YP
Sbjct: 87 RARQNRAYLERDCPAQLQQLLELGRGVLDQQVTT----------------LRCRALNYYP 130
Query: 231 KPVWVMWMRGEQEQQGTQ--RGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQ 288
+ + + W++ +Q + D+LP+ DGT+ TL V GE +C+V+H L+ Q
Sbjct: 131 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLD-Q 189
Query: 289 DIVLYWEHHSSVGFII-----LAVIVPLLLLIGLALWFRKR 324
+++ WE S +I +AV V +L + L + RKR
Sbjct: 190 PLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 230
>gi|24797076 major histocompatibility complex, class II, DP beta 1
precursor [Homo sapiens]
Length = 258
Score = 57.0 bits (136), Expect = 2e-08
Identities = 33/107 (30%), Positives = 57/107 (53%), Gaps = 3/107 (2%)
Query: 194 GKAHLQRQVKPEAWLSHGPS-PGPGHLQLVCHVSGFYPKPVWVMW-MRGEQEQQGTQRGD 251
G LQR+V+P +S P H LVCHV+ FYP + V W + G++E G +
Sbjct: 114 GPMTLQRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTN 173
Query: 252 ILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHS 298
++ + D T+ + LE+ + +C+V+H+SL+ + + W+ S
Sbjct: 174 LIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLD-SPVTVEWKAQS 219
>gi|4557751 MHC class I polypeptide-related sequence A [Homo
sapiens]
Length = 383
Score = 55.8 bits (133), Expect = 5e-08
Identities = 57/224 (25%), Positives = 99/224 (44%), Gaps = 27/224 (12%)
Query: 103 HELQFEYPFEIQVTGGCELHSGKVSGSFLQLAYQGSDFVS--FQNNSW-LPYPV-AGNMA 158
H LQ EI+V CE+H + S Y G F+S + W +P A +A
Sbjct: 111 HSLQ-----EIRV---CEIHEDNSTRSSQHFYYDGELFLSQNLETKEWTMPQSSRAQTLA 162
Query: 159 KHFCKVLNQNQHENDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGH 218
+ L ++ + ++ + C + + L +G L+R V P ++ + G+
Sbjct: 163 MNVRNFLKEDAMKTKTHYHAMHADCLQELRRYLKSGVV-LRRTVPPMVNVTRSEA-SEGN 220
Query: 219 LQLVCHVSGFYPKPVWVMWMR-GEQEQQGTQR-GDILPSADGTWYLRATLEVAAGEAADL 276
+ + C SGFYP + + W + G TQ+ GD+LP +GT+ + GE
Sbjct: 221 ITVTCRASGFYPWNITLSWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRF 280
Query: 277 SCRVKHSS-------LEGQDIVL--YWE--HHSSVGFIILAVIV 309
+C ++HS G+ +VL +W+ H S+V + VI+
Sbjct: 281 TCYMEHSGNHSTHPVPSGKVLVLQSHWQTFHVSAVAAAAIFVII 324
>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
sapiens]
Length = 168
Score = 55.1 bits (131), Expect = 9e-08
Identities = 34/111 (30%), Positives = 57/111 (51%), Gaps = 8/111 (7%)
Query: 221 LVCHVSGFYPKPVWVMWMRGEQEQQGTQ--RGDILPSADGTWYLRATLEVAAGEAADLSC 278
L C +YP+ + + W++ +Q + D+LP+ DGT+ TL V GE +C
Sbjct: 43 LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 102
Query: 279 RVKHSSLEGQDIVLYWEHHSSVGFII-----LAVIVPLLLLIGLALWFRKR 324
+V+H L+ Q +++ WE S +I +AV V +L + L + RKR
Sbjct: 103 QVEHPGLD-QPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 152
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.459
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,575,149
Number of Sequences: 37866
Number of extensions: 699143
Number of successful extensions: 1791
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 76
Number of HSP's successfully gapped in prelim test: 45
Number of HSP's that attempted gapping in prelim test: 1612
Number of HSP's gapped (non-prelim): 136
length of query: 327
length of database: 18,247,518
effective HSP length: 103
effective length of query: 224
effective length of database: 14,347,320
effective search space: 3213799680
effective search space used: 3213799680
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.