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Search of human proteins with 149158702
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|149158702 major histocompatibility complex, class I, F
isoform 1 precursor [Homo sapiens]
(442 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|149158702 major histocompatibility complex, class I, F isofor... 916 0.0
gi|149158698 major histocompatibility complex, class I, F isofor... 715 0.0
gi|24797067 major histocompatibility complex, class I, A precurs... 578 e-165
gi|17986001 major histocompatibility complex, class I, B precurs... 568 e-162
gi|4504415 major histocompatibility complex, class I, G precurso... 553 e-158
gi|52630342 major histocompatibility complex, class I, C precurs... 551 e-157
gi|62912479 major histocompatibility complex, class I, E precurs... 520 e-148
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 457 e-129
gi|149158700 major histocompatibility complex, class I, F isofor... 421 e-118
gi|4504417 major histocompatibility complex, class I-related [Ho... 222 6e-58
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 202 4e-52
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 191 9e-49
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 189 6e-48
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 186 5e-47
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 166 3e-41
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 149 4e-36
gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H... 140 2e-33
gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom... 140 2e-33
gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi... 140 3e-33
gi|167857788 MHC class I polypeptide-related sequence B [Homo sa... 137 2e-32
gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s... 116 4e-26
gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa... 116 4e-26
gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sa... 108 7e-24
gi|110618224 CD1A antigen precursor [Homo sapiens] 82 1e-15
gi|239740920 PREDICTED: similar to major histocompatibility comp... 75 1e-13
gi|239740918 PREDICTED: similar to major histocompatibility comp... 75 1e-13
gi|4504399 major histocompatibility complex, class II, DM beta p... 73 5e-13
gi|169168591 PREDICTED: similar to major histocompatibility comp... 72 1e-12
gi|24797076 major histocompatibility complex, class II, DP beta ... 70 3e-12
gi|4502649 CD1D antigen precursor [Homo sapiens] 68 1e-11
>gi|149158702 major histocompatibility complex, class I, F isoform 1
precursor [Homo sapiens]
Length = 442
Score = 916 bits (2368), Expect = 0.0
Identities = 442/442 (100%), Positives = 442/442 (100%)
Query: 1 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD
Sbjct: 1 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
Query: 61 AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN
Sbjct: 61 AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
Query: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY
Sbjct: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
Query: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR
Sbjct: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
Query: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300
DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ
Sbjct: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300
Query: 301 PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAAAYSVVSGNLMITWWS 360
PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAAAYSVVSGNLMITWWS
Sbjct: 301 PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAAAYSVVSGNLMITWWS 360
Query: 361 SLFLLGVLFQGYLGCLRSHSVLGRRKVGDMWILFFLWLWTSFNTAFLALQSLRFGFGFRR 420
SLFLLGVLFQGYLGCLRSHSVLGRRKVGDMWILFFLWLWTSFNTAFLALQSLRFGFGFRR
Sbjct: 361 SLFLLGVLFQGYLGCLRSHSVLGRRKVGDMWILFFLWLWTSFNTAFLALQSLRFGFGFRR 420
Query: 421 GRSFLLRSWHHLMKRVQIKIFD 442
GRSFLLRSWHHLMKRVQIKIFD
Sbjct: 421 GRSFLLRSWHHLMKRVQIKIFD 442
>gi|149158698 major histocompatibility complex, class I, F isoform 2
precursor [Homo sapiens]
Length = 346
Score = 715 bits (1846), Expect = 0.0
Identities = 345/345 (100%), Positives = 345/345 (100%)
Query: 1 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD
Sbjct: 1 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
Query: 61 AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN
Sbjct: 61 AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
Query: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY
Sbjct: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
Query: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR
Sbjct: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
Query: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300
DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ
Sbjct: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300
Query: 301 PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAA 345
PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAA
Sbjct: 301 PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAA 345
>gi|24797067 major histocompatibility complex, class I, A precursor
[Homo sapiens]
Length = 365
Score = 578 bits (1491), Expect = e-165
Identities = 278/353 (78%), Positives = 305/353 (86%)
Query: 1 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
MAPR+LLLLLSGALALT TWAGSHS+RYF T+VSRPGRGEPR+IAV YVDDTQF+RFDSD
Sbjct: 4 MAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSD 63
Query: 61 AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
AA RMEPR PW+EQEGP+YW+ T KA +QTDRV L L YNQSEAGSHT+Q M
Sbjct: 64 AASQRMEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMY 123
Query: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
GCD+G DGR LRGY Q AYDGKDYI+LNEDLRSWTAAD AQIT+R +EA AE+ R Y
Sbjct: 124 GCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEAEQLRAY 183
Query: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
L+G C+E LRRYLENGKETLQR DPPK H+ HHPISDHEATLRCWALGFYPAEITLTWQR
Sbjct: 184 LDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQR 243
Query: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300
DGE+QTQDTELVETRPAGDGTFQKWAAVVVP GEEQRYTCHVQHEGLP+PL LRWE S Q
Sbjct: 244 DGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQ 303
Query: 301 PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAAAYSVVSGN 353
PTIPIVGI+AGLV+LGAV+TGAVVAAVMWR+KSSDR GSY+QAA+ G+
Sbjct: 304 PTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQGS 356
>gi|17986001 major histocompatibility complex, class I, B precursor
[Homo sapiens]
Length = 362
Score = 568 bits (1464), Expect = e-162
Identities = 276/353 (78%), Positives = 302/353 (85%)
Query: 1 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
MAPR++LLLLS ALALT+TWAGSHS+RYF T+VSRPGRGEPR+I+V YVDDTQF+RFDSD
Sbjct: 4 MAPRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSD 63
Query: 61 AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
AA PR EPR PW+EQEGP+YW+ T KA AQTDR +LRNL YNQSEAGSHTLQ M
Sbjct: 64 AASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMY 123
Query: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
GCD+GPDGRLLRG+ Q+AYDGKDYI+LNEDLRSWTAADT AQITQR +EA AE+ R Y
Sbjct: 124 GCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQRRAY 183
Query: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
LEGEC+E LRRYLENGK+ L+RADPPK HV HHPISDHEATLRCWALGFYPAEITLTWQR
Sbjct: 184 LEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQR 243
Query: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300
DGE+QTQDTELVETRPAGD TFQKWAAVVVP GEEQRYTCHVQHEGLP+PL LRWE S Q
Sbjct: 244 DGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQ 303
Query: 301 PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAAAYSVVSGN 353
T+PIVGIVAGL VL VV GAVVAAVM R+KSS GSYSQAA G+
Sbjct: 304 STVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSYSQAACSDSAQGS 356
>gi|4504415 major histocompatibility complex, class I, G precursor
[Homo sapiens]
Length = 338
Score = 553 bits (1426), Expect = e-158
Identities = 265/335 (79%), Positives = 292/335 (87%)
Query: 1 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
MAPR+L LLLSGAL LT+TWAGSHS+RYFS AVSRPGRGEPR+IA+ YVDDTQF+RFDSD
Sbjct: 4 MAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSD 63
Query: 61 AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
+A PRMEPR PWVEQEGP+YWE T KA+AQTDR+ L+ L YNQSEA SHTLQ M
Sbjct: 64 SACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQWMI 123
Query: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
GCD+G DGRLLRGY Q+AYDGKDY++LNEDLRSWTAADT AQI++R EA AE+ R Y
Sbjct: 124 GCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANVAEQRRAY 183
Query: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
LEG C+E L RYLENGKE LQRADPPK HV HHP+ D+EATLRCWALGFYPAEI LTWQR
Sbjct: 184 LEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILTWQR 243
Query: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300
DGE+QTQD ELVETRPAGDGTFQKWAAVVVP GEEQRYTCHVQHEGLP+PL+LRW+QS
Sbjct: 244 DGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSSL 303
Query: 301 PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSD 335
PTIPI+GIVAGLVVL AVVTGA VAAV+WRKKSSD
Sbjct: 304 PTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSSD 338
>gi|52630342 major histocompatibility complex, class I, C precursor
[Homo sapiens]
Length = 366
Score = 551 bits (1419), Expect = e-157
Identities = 271/354 (76%), Positives = 297/354 (83%), Gaps = 1/354 (0%)
Query: 1 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
MAPR+LLLLLSG LALT+TWA SHS+RYF TAVSRPGRGEPR+I+V YVDDTQF+RFDSD
Sbjct: 4 MAPRALLLLLSGGLALTETWACSHSMRYFDTAVSRPGRGEPRFISVGYVDDTQFVRFDSD 63
Query: 61 AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
AA PR EPR PWVEQEGP+YW+ T K AQ DRV+LRNL YNQSE GSHTLQ M+
Sbjct: 64 AASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQADRVSLRNLRGYYNQSEDGSHTLQRMS 123
Query: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
GCD+GPDGRLLRGY Q AYDGKDYI+LNEDLRSWTAADT AQITQR EA AE+ R Y
Sbjct: 124 GCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAARAAEQLRAY 183
Query: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
LEG C+E LRRYLENGKETLQRA+PPK HV HHP+SDHEATLRCWALGFYPAEITLTWQR
Sbjct: 184 LEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPAEITLTWQR 243
Query: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300
DGE+QTQDTELVETRPAGDGTFQKWAAVVVP G+EQRYTCH+QHEGL +PL L WE S Q
Sbjct: 244 DGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQEPLTLSWEPSSQ 303
Query: 301 PTIPIVGIVAGLVVLGAV-VTGAVVAAVMWRKKSSDRNRGSYSQAAAYSVVSGN 353
PTIPI+GIVAGL VL + V GAVV A+M R+KSS GS SQAA + G+
Sbjct: 304 PTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSGGKGGSCSQAACSNSAQGS 357
>gi|62912479 major histocompatibility complex, class I, E precursor
[Homo sapiens]
Length = 358
Score = 520 bits (1340), Expect = e-148
Identities = 251/344 (72%), Positives = 284/344 (82%)
Query: 1 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
M +LLLLLS ALALT TWAGSHSL+YF T+VSRPGRGEPR+I+V YVDDTQF+RFD+D
Sbjct: 1 MVDGTLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDND 60
Query: 61 AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
AA PRM PR PW+EQEG +YW+ T A+ AQ RV LR L YNQSEAGSHTLQ M+
Sbjct: 61 AASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMH 120
Query: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
GC++GPDGR LRGY Q AYDGKDY++LNEDLRSWTA DT AQI+++ AE R Y
Sbjct: 121 GCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAY 180
Query: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
LE C+E L +YLE GKETL +PPK HV HHPISDHEATLRCWALGFYPAEITLTWQ+
Sbjct: 181 LEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQ 240
Query: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300
DGE TQDTELVETRPAGDGTFQKWAAVVVP GEEQRYTCHVQHEGLP+P+ LRW+ + Q
Sbjct: 241 DGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQ 300
Query: 301 PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQA 344
PTIPIVGI+AGLV+LG+VV+GAVVAAV+WRKKSS GSYS+A
Sbjct: 301 PTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKA 344
>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
sapiens]
Length = 366
Score = 457 bits (1177), Expect = e-129
Identities = 227/330 (68%), Positives = 258/330 (78%), Gaps = 4/330 (1%)
Query: 22 GSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIPRMEPREPWVEQEGPQYW 81
GSHSLRYF TAVSRPG GEPR+I+V YVDDTQF+RFDSD+A PR EPR PW+EQEGP+YW
Sbjct: 38 GSHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQEGPEYW 97
Query: 82 EWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCDMGPDGRLLRGYHQHAYDG 141
+ T K AQ+ RV L L YNQSEAGSHTLQ M GCD+GPDGR LRG+ Q AYDG
Sbjct: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDG 157
Query: 142 KDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTYLEGECLELLRRYLENGKETLQ 201
+DYI+LNEDLRSWTAADT AQIT+R EA AE R YLEG C+E LRRYLE GK+ L
Sbjct: 158 RDYIALNEDLRSWTAADTAAQITKRKREAAGAAERQRNYLEGRCVEGLRRYLETGKDALL 217
Query: 202 RADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDGEEQTQDTELVETRPAGDGT 261
RADPPKAHV HHPIS+ E TLRCWALGFYP EI+LTWQR+GE+QTQD ELVETRP+GDGT
Sbjct: 218 RADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDGT 277
Query: 262 FQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTG 321
FQKWAA+VVP GEEQRYTC VQHEGL +PL LRWE PQ + I+GI+ GLV+L V
Sbjct: 278 FQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWE-PPQTSFLIMGIIVGLVLL---VVA 333
Query: 322 AVVAAVMWRKKSSDRNRGSYSQAAAYSVVS 351
V AV+WRKK S R S+ + ++ VS
Sbjct: 334 LVAGAVIWRKKRSGREGREGSEFSCHNGVS 363
>gi|149158700 major histocompatibility complex, class I, F isoform 3
precursor [Homo sapiens]
Length = 254
Score = 421 bits (1083), Expect = e-118
Identities = 203/204 (99%), Positives = 204/204 (100%)
Query: 1 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD
Sbjct: 1 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
Query: 61 AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN
Sbjct: 61 AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
Query: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY
Sbjct: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
Query: 181 LEGECLELLRRYLENGKETLQRAD 204
LEGECLELLRRYLENGKETLQRA+
Sbjct: 181 LEGECLELLRRYLENGKETLQRAE 204
Score = 99.8 bits (247), Expect = 5e-21
Identities = 51/52 (98%), Positives = 51/52 (98%)
Query: 294 RWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAA 345
R EQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAA
Sbjct: 202 RAEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAA 253
>gi|4504417 major histocompatibility complex, class I-related [Homo
sapiens]
Length = 341
Score = 222 bits (565), Expect = 6e-58
Identities = 133/342 (38%), Positives = 192/342 (56%), Gaps = 17/342 (4%)
Query: 5 SLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIP 64
+ LL L L + + + +HSLRYF VS P G P +I+V YVD +DS
Sbjct: 6 AFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS--VTR 63
Query: 65 RMEPREPWV-EQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCD 123
+ EPR PW+ E P +WE T + Q +V L+ L R YN S GSHT Q M GC+
Sbjct: 64 QKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHS--GSHTYQRMIGCE 121
Query: 124 MGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEF-RTYLE 182
+ DG G+ Q+AYDG+D++ N+D SW A D VA ++ +EA ++ + + +LE
Sbjct: 122 LLEDGSTT-GFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLE 180
Query: 183 GECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDG 242
EC+ L+R+LE GK+TLQR +PP V L C A GFYP EI +TW ++G
Sbjct: 181 EECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNG 240
Query: 243 EEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ-- 300
EE Q+ + + P+GDGT+Q WA++ + P Y+CHV+H G+ L Q PQ
Sbjct: 241 EEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVL-----QVPQES 295
Query: 301 PTIPIV-GIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSY 341
TIP+V V+G +VL V+ G V ++WR++ ++N Y
Sbjct: 296 ETIPLVMKAVSGSIVLVIVLAG--VGVLVWRRRPREQNGAIY 335
>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
sapiens]
Length = 348
Score = 202 bits (515), Expect = 4e-52
Identities = 121/342 (35%), Positives = 180/342 (52%), Gaps = 9/342 (2%)
Query: 3 PRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAA 62
P LLL+L L SHSL Y S G + A+ YVDD F+ +D ++
Sbjct: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
Query: 63 IPRMEPREPWVEQE-GPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNG 121
R+EPR PWV Q W + K V ++ +N S+ SHTLQ + G
Sbjct: 67 --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILG 123
Query: 122 CDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEY-AEEFRTY 180
C+M D GY ++ YDG+D++ D W AA+ A T+ +E + A + R Y
Sbjct: 124 CEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182
Query: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
LE +C L++ LE G+ L + PP V HH ++ TLRC AL +YP IT+ W +
Sbjct: 183 LERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLK 241
Query: 241 DGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSP 299
D + ++ E + P GDGT+Q W + VPPGEEQRYTC V+H GL QPLI+ WE SP
Sbjct: 242 DKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSP 301
Query: 300 QPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSY 341
T+ ++G+++G+ V ++ ++ ++ +++ S G Y
Sbjct: 302 SGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 342
>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
Length = 298
Score = 191 bits (486), Expect = 9e-49
Identities = 107/293 (36%), Positives = 156/293 (53%), Gaps = 6/293 (2%)
Query: 7 LLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIPRM 66
LLLL G + G +SL Y T +S+ P + A+ ++D QF R++S +
Sbjct: 11 LLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDR--KS 68
Query: 67 EPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCDMGP 126
+P W + EG + W+ + KA L++++ YN S GSH LQG GC++
Sbjct: 69 QPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSN-GSHVLQGRFGCEI-E 126
Query: 127 DGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEE-YAEEFRTYLEGEC 185
+ R + ++ YDGKDYI N+++ +W D AQIT++ +EAE Y + + YLE EC
Sbjct: 127 NNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYLEEEC 186
Query: 186 LELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDGEEQ 245
LR+YL+ K L R DPP V H + L+C A FYP +I + W R GE Q
Sbjct: 187 PATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGEVQ 246
Query: 246 TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQS 298
+ + G+GT+Q W V VPP + Y+CHVQH L QPL++ WE S
Sbjct: 247 EPELR-GDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEAS 298
>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
sapiens]
Length = 325
Score = 189 bits (479), Expect = 6e-48
Identities = 108/303 (35%), Positives = 166/303 (54%), Gaps = 9/303 (2%)
Query: 42 RYIAVEYVDDTQFLRFDSDAAIPRMEPREPWVEQE-GPQYWEWTTGYAKANAQTDRVALR 100
R + + YVDD F+ +D ++ R+EPR PWV Q W + K V
Sbjct: 23 RLLPLGYVDDQLFVFYDHESR--RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFW 80
Query: 101 NLLRRYNQSEAGSHTLQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTV 160
++ +N S+ SHTLQ + GC+M D GY ++ YDG+D++ D W AA+
Sbjct: 81 TIMENHNHSKE-SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPR 138
Query: 161 AQITQRFYEAEEY-AEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHE 219
A T+ +E + A + R YLE +C L++ LE G+ L + PP V HH ++
Sbjct: 139 AWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSV 197
Query: 220 ATLRCWALGFYPAEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRY 278
TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q W + VPPGEEQRY
Sbjct: 198 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 257
Query: 279 TCHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNR 338
TC V+H GL QPLI+ WE SP T+ ++G+++G+ V ++ ++ ++ +++ S
Sbjct: 258 TCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 316
Query: 339 GSY 341
G Y
Sbjct: 317 GHY 319
>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
sapiens]
Length = 334
Score = 186 bits (471), Expect = 5e-47
Identities = 116/342 (33%), Positives = 173/342 (50%), Gaps = 23/342 (6%)
Query: 3 PRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAA 62
P LLL+L L SHSL Y S G + A+ YVDD F+ +D ++
Sbjct: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
Query: 63 IPRMEPREPWVEQE-GPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNG 121
R+EPR PWV Q W + K V ++ +N S+ SHTLQ + G
Sbjct: 67 --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILG 123
Query: 122 CDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEY-AEEFRTY 180
C+M D GY ++ YDG+D++ D W AA+ A T+ +E + A + R Y
Sbjct: 124 CEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182
Query: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
LE +C L++ LE G+ L + TLRC AL +YP IT+ W +
Sbjct: 183 LERDCPAQLQQLLELGRGVLDQ---------------QVTTLRCRALNYYPQNITMKWLK 227
Query: 241 DGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSP 299
D + ++ E + P GDGT+Q W + VPPGEEQRYTC V+H GL QPLI+ WE SP
Sbjct: 228 DKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSP 287
Query: 300 QPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSY 341
T+ ++G+++G+ V ++ ++ ++ +++ S G Y
Sbjct: 288 SGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 328
>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
sapiens]
Length = 260
Score = 166 bits (421), Expect = 3e-41
Identities = 88/231 (38%), Positives = 134/231 (58%), Gaps = 5/231 (2%)
Query: 113 SHTLQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEE 172
SHTLQ + GC+M D GY ++ YDG+D++ D W AA+ A T+ +E +
Sbjct: 27 SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
Query: 173 Y-AEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYP 231
A + R YLE +C L++ LE G+ L + PP V HH ++ TLRC AL +YP
Sbjct: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYP 144
Query: 232 AEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQP 290
IT+ W +D + ++ E + P GDGT+Q W + VPPGEEQRYTC V+H GL QP
Sbjct: 145 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 204
Query: 291 LILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSY 341
LI+ WE SP T+ ++G+++G+ V ++ ++ ++ +++ S G Y
Sbjct: 205 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 254
>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
sapiens]
Length = 246
Score = 149 bits (377), Expect = 4e-36
Identities = 83/231 (35%), Positives = 127/231 (54%), Gaps = 19/231 (8%)
Query: 113 SHTLQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEE 172
SHTLQ + GC+M D GY ++ YDG+D++ D W AA+ A T+ +E +
Sbjct: 27 SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
Query: 173 Y-AEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYP 231
A + R YLE +C L++ LE G+ L + TLRC AL +YP
Sbjct: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQ---------------QVTTLRCRALNYYP 130
Query: 232 AEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQP 290
IT+ W +D + ++ E + P GDGT+Q W + VPPGEEQRYTC V+H GL QP
Sbjct: 131 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 190
Query: 291 LILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSY 341
LI+ WE SP T+ ++G+++G+ V ++ ++ ++ +++ S G Y
Sbjct: 191 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 240
>gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 140 bits (354), Expect = 2e-33
Identities = 105/332 (31%), Positives = 163/332 (49%), Gaps = 22/332 (6%)
Query: 6 LLLLLSGALALTDTWAGSH-SLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIP 64
LL LL G+L A SH SL Y TAVS P G P + ++ Q+L ++S
Sbjct: 14 LLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRG-- 66
Query: 65 RMEPREPWV-EQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCD 123
EP WV E + YWE T + + A + L G +TLQG+ GC+
Sbjct: 67 EAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKAL------GGKGPYTLQGLLGCE 120
Query: 124 MGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVA-QITQRFYEAEEYAEEFRTYLE 182
+GPD + + A +G+++++ + +W A I+QR+ + ++ A + T+L
Sbjct: 121 LGPDNTSVPTA-KFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLL 179
Query: 183 GECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDG 242
C LR +LE G+ L+ +PP + P S + L C A FYP E+ L + R+G
Sbjct: 180 FSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNG 239
Query: 243 EEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQPT 302
T + P DG+F +++ V G+E Y C VQH GL QPL + E + +
Sbjct: 240 --LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSS 297
Query: 303 IPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSS 334
+ +VGIV G+++L A G A++WR+ S
Sbjct: 298 VLVVGIVIGVLLLTAAAVG---GALLWRRMRS 326
>gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 140 bits (354), Expect = 2e-33
Identities = 105/332 (31%), Positives = 163/332 (49%), Gaps = 22/332 (6%)
Query: 6 LLLLLSGALALTDTWAGSH-SLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIP 64
LL LL G+L A SH SL Y TAVS P G P + ++ Q+L ++S
Sbjct: 14 LLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRG-- 66
Query: 65 RMEPREPWV-EQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCD 123
EP WV E + YWE T + + A + L G +TLQG+ GC+
Sbjct: 67 EAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKAL------GGKGPYTLQGLLGCE 120
Query: 124 MGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVA-QITQRFYEAEEYAEEFRTYLE 182
+GPD + + A +G+++++ + +W A I+QR+ + ++ A + T+L
Sbjct: 121 LGPDNTSVPTA-KFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLL 179
Query: 183 GECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDG 242
C LR +LE G+ L+ +PP + P S + L C A FYP E+ L + R+G
Sbjct: 180 FSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNG 239
Query: 243 EEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQPT 302
T + P DG+F +++ V G+E Y C VQH GL QPL + E + +
Sbjct: 240 --LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSS 297
Query: 303 IPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSS 334
+ +VGIV G+++L A G A++WR+ S
Sbjct: 298 VLVVGIVIGVLLLTAAAVG---GALLWRRMRS 326
>gi|4557751 MHC class I polypeptide-related sequence A [Homo
sapiens]
Length = 383
Score = 140 bits (352), Expect = 3e-33
Identities = 94/293 (32%), Positives = 150/293 (51%), Gaps = 22/293 (7%)
Query: 6 LLLLLSGALALTDTWAGS--HSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAI 63
+ LLL+G A + HSLRY T +S G + ++ ++D FLR D
Sbjct: 6 VFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQKC- 64
Query: 64 PRMEPREPWVEQE-GPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGC 122
R +P+ W E G + W+ T N + R+ L ++ + G H+LQ + C
Sbjct: 65 -RAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHI----KDQKEGLHSLQEIRVC 119
Query: 123 DMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTA-----ADTVAQITQRFYEAEEYAEEF 177
++ D H + YDG+ ++S N + + WT A T+A + F + E A +
Sbjct: 120 EIHEDNSTRSSQHFY-YDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLK--EDAMKT 176
Query: 178 RTY---LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEI 234
+T+ + +CL+ LRRYL++G L+R PP +V S+ T+ C A GFYP I
Sbjct: 177 KTHYHAMHADCLQELRRYLKSGV-VLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNI 235
Query: 235 TLTWQRDGEEQTQDT-ELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEG 286
TL+W++DG + DT + + P G+GT+Q W A + GEEQR+TC+++H G
Sbjct: 236 TLSWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSG 288
>gi|167857788 MHC class I polypeptide-related sequence B [Homo
sapiens]
Length = 383
Score = 137 bits (345), Expect = 2e-32
Identities = 89/276 (32%), Positives = 143/276 (51%), Gaps = 20/276 (7%)
Query: 21 AGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIPRMEPREPWVEQE-GPQ 79
A HSLRY +S+ G + ++A ++D FLR+D R +P+ W E G +
Sbjct: 23 AEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKR--RAKPQGQWAENVLGAK 80
Query: 80 YWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCDMGPDGRLLRGYHQHAY 139
W+ T N Q LR L + G H+LQ + C++ D RG Y
Sbjct: 81 TWDTETEDLTENGQD----LRRTLTHIKDQKGGLHSLQEIRVCEIHEDSST-RGSRHFYY 135
Query: 140 DGKDYISLNEDLRSWTA-----ADTVAQITQRFYEAEEYAEEFRTY---LEGECLELLRR 191
DG+ ++S N + + T A T+A F++ E A + +T+ ++ +CL+ L+R
Sbjct: 136 DGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWK--EDAMKTKTHYRAMQADCLQKLQR 193
Query: 192 YLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDGEEQTQDT-E 250
YL++G ++R PP +V +S+ T+ C A FYP ITLTW++DG + +T +
Sbjct: 194 YLKSGV-AIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQ 252
Query: 251 LVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEG 286
+ P G+GT+Q W A + GEEQR+TC+++H G
Sbjct: 253 WGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSG 288
>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
sapiens]
Length = 168
Score = 116 bits (291), Expect = 4e-26
Identities = 55/138 (39%), Positives = 84/138 (60%), Gaps = 3/138 (2%)
Query: 205 PPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQ 263
PP V HH ++ TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q
Sbjct: 27 PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85
Query: 264 KWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAV 323
W + VPPGEEQRYTC V+H GL QPLI+ WE SP T+ ++G+++G+ V ++ +
Sbjct: 86 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGI 144
Query: 324 VAAVMWRKKSSDRNRGSY 341
+ ++ +++ S G Y
Sbjct: 145 LFIILRKRQGSRGAMGHY 162
>gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
sapiens]
Length = 256
Score = 116 bits (291), Expect = 4e-26
Identities = 55/138 (39%), Positives = 84/138 (60%), Gaps = 3/138 (2%)
Query: 205 PPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQ 263
PP V HH ++ TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q
Sbjct: 115 PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 173
Query: 264 KWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAV 323
W + VPPGEEQRYTC V+H GL QPLI+ WE SP T+ ++G+++G+ V ++ +
Sbjct: 174 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGI 232
Query: 324 VAAVMWRKKSSDRNRGSY 341
+ ++ +++ S G Y
Sbjct: 233 LFIILRKRQGSRGAMGHY 250
Score = 45.8 bits (107), Expect = 8e-05
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 3 PRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAA 62
P LLL+L L SHSL Y S G + A+ YVDD F+ +D ++
Sbjct: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
Query: 63 IPRMEPREPWVEQE-GPQYW 81
R+EPR PWV Q W
Sbjct: 67 --RVEPRTPWVSSRISSQMW 84
>gi|21040341 hemochromatosis protein isoform 3 precursor [Homo
sapiens]
Length = 242
Score = 108 bits (271), Expect = 7e-24
Identities = 50/122 (40%), Positives = 77/122 (63%), Gaps = 2/122 (1%)
Query: 221 TLRCWALGFYPAEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYT 279
TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q W + VPPGEEQRYT
Sbjct: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175
Query: 280 CHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRG 339
C V+H GL QPLI+ WE SP T+ ++G+++G+ V ++ ++ ++ +++ S G
Sbjct: 176 CQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 234
Query: 340 SY 341
Y
Sbjct: 235 HY 236
Score = 47.0 bits (110), Expect = 3e-05
Identities = 34/119 (28%), Positives = 50/119 (42%), Gaps = 3/119 (2%)
Query: 3 PRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAA 62
P LLL+L L SHSL Y S G + A+ YVDD F+ +D ++
Sbjct: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
Query: 63 IPRMEPREPWVEQE-GPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
R+EPR PWV Q W + K V ++ +N S+ + + +N
Sbjct: 67 --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVTTLRCRALN 123
>gi|110618224 CD1A antigen precursor [Homo sapiens]
Length = 327
Score = 81.6 bits (200), Expect = 1e-15
Identities = 56/206 (27%), Positives = 93/206 (45%), Gaps = 10/206 (4%)
Query: 116 LQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEA----E 171
+Q GC++ G++ + Q AY G D++S + SW + + F + +
Sbjct: 113 IQVTGGCELH-SGKVSGSFLQLAYQGSDFVSFQNN--SWLPYPVAGNMAKHFCKVLNQNQ 169
Query: 172 EYAEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPI-SDHEATLRCWALGFY 230
+ L C + L+ GK LQR P+A ++H P L C GFY
Sbjct: 170 HENDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFY 229
Query: 231 PAEITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLP-Q 289
P + + W R GE++ Q T+ + P+ DGT+ A + V GE +C V+H L Q
Sbjct: 230 PKPVWVMWMR-GEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQ 288
Query: 290 PLILRWEQSPQPTIPIVGIVAGLVVL 315
++L WE I+ ++ L++L
Sbjct: 289 DIVLYWEHHSSVGFIILAVIVPLLLL 314
>gi|239740920 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 2 [Homo sapiens]
Length = 261
Score = 75.1 bits (183), Expect = 1e-13
Identities = 54/194 (27%), Positives = 86/194 (44%), Gaps = 11/194 (5%)
Query: 131 LRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAE-EYAEEFRTYLEGECLELL 189
+RG ++ Y+ ++Y + D+ + A + ++ ++ E E R L+ C
Sbjct: 56 VRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRH-- 113
Query: 190 RRYLENGKETLQRADPPKAHVAHHPIS--DHEATLRCWALGFYPAEITLTWQRDGEEQTQ 247
Y + TLQR P ++ +H L C FYPA+I + W R+ +E+T
Sbjct: 114 -NYQLELRTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETT 172
Query: 248 DTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRW---EQSPQPTI- 303
GD TFQ + + P YTCHV+H L P+I+ W +S Q +
Sbjct: 173 GVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKML 232
Query: 304 -PIVGIVAGLVVLG 316
I G V GL+ LG
Sbjct: 233 SGIGGFVLGLIFLG 246
>gi|239740918 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 1 [Homo sapiens]
Length = 281
Score = 75.1 bits (183), Expect = 1e-13
Identities = 54/194 (27%), Positives = 86/194 (44%), Gaps = 11/194 (5%)
Query: 131 LRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAE-EYAEEFRTYLEGECLELL 189
+RG ++ Y+ ++Y + D+ + A + ++ ++ E E R L+ C
Sbjct: 56 VRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRH-- 113
Query: 190 RRYLENGKETLQRADPPKAHVAHHPIS--DHEATLRCWALGFYPAEITLTWQRDGEEQTQ 247
Y + TLQR P ++ +H L C FYPA+I + W R+ +E+T
Sbjct: 114 -NYQLELRTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETT 172
Query: 248 DTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRW---EQSPQPTI- 303
GD TFQ + + P YTCHV+H L P+I+ W +S Q +
Sbjct: 173 GVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKML 232
Query: 304 -PIVGIVAGLVVLG 316
I G V GL+ LG
Sbjct: 233 SGIGGFVLGLIFLG 246
>gi|4504399 major histocompatibility complex, class II, DM beta
precursor [Homo sapiens]
Length = 263
Score = 73.2 bits (178), Expect = 5e-13
Identities = 44/135 (32%), Positives = 71/135 (52%), Gaps = 8/135 (5%)
Query: 202 RADPPKAHVAHH-PISDHEAT-LRCWALGFYPAEITLTWQRDGEEQTQDTELVET-RPAG 258
R PP VA P + E L C+ GFYPAE+T+TW+++G+ + +T +P G
Sbjct: 111 RTRPPSVQVAKTTPFNTREPVMLACYVWGFYPAEVTITWRKNGKLVMPHSSAHKTAQPNG 170
Query: 259 DGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQ--SPQPTIPIVGIVAGLVVLG 316
D T+Q + + + P YTC V+H G P+P++ W SP T+ V + A + LG
Sbjct: 171 DWTYQTLSHLALTPSYGDTYTCVVEHIGAPEPILRDWTPGLSPMQTLK-VSVSAVTLGLG 229
Query: 317 AVVTGAVVAAVMWRK 331
++ + + WR+
Sbjct: 230 LIIFS--LGVISWRR 242
>gi|169168591 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 isoform 1 [Homo sapiens]
Length = 261
Score = 72.0 bits (175), Expect = 1e-12
Identities = 52/194 (26%), Positives = 85/194 (43%), Gaps = 11/194 (5%)
Query: 131 LRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAE-EYAEEFRTYLEGECLELL 189
+RG ++ Y+ ++Y + D+ + A + ++ ++ E E R ++ C
Sbjct: 56 VRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRASVDTVCRH-- 113
Query: 190 RRYLENGKETLQRADPPKAHVAHHPIS--DHEATLRCWALGFYPAEITLTWQRDGEEQTQ 247
Y + TLQR P ++ +H L C FYPA+I + W R+ +E+T
Sbjct: 114 -NYQLELRTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETA 172
Query: 248 DTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRW---EQSPQPTI- 303
GD TFQ + + P YTCHV+H L P+ + W +S Q +
Sbjct: 173 GVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKML 232
Query: 304 -PIVGIVAGLVVLG 316
I G V GL+ LG
Sbjct: 233 SGIGGFVLGLIFLG 246
>gi|24797076 major histocompatibility complex, class II, DP beta 1
precursor [Homo sapiens]
Length = 258
Score = 70.5 bits (171), Expect = 3e-12
Identities = 52/213 (24%), Positives = 89/213 (41%), Gaps = 11/213 (5%)
Query: 132 RGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAE-EYAEEFRTYLEGECLELLR 190
R ++ Y+ +++ + D+ + A + + ++ ++ + EE R + C
Sbjct: 52 RFLERYIYNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRH--- 108
Query: 191 RYLENGKETLQRADPPKAHVAHH---PISDHEATLRCWALGFYPAEITLTWQRDGEEQTQ 247
Y G TLQR P+ +V+ P+ H L C FYP I + W +G+E+T
Sbjct: 109 NYELGGPMTLQRRVQPRVNVSPSKKGPLQHHNL-LVCHVTDFYPGSIQVRWFLNGQEETA 167
Query: 248 DTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQPTIPIVG 307
GD TFQ + + P + YTC V+H L P+ + W+
Sbjct: 168 GVVSTNLIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTL 227
Query: 308 IVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGS 340
AG VLG ++ G + ++S RGS
Sbjct: 228 TGAGGFVLGLIICG---VGIFMHRRSKKVQRGS 257
>gi|4502649 CD1D antigen precursor [Homo sapiens]
Length = 335
Score = 68.2 bits (165), Expect = 1e-11
Identities = 54/186 (29%), Positives = 81/186 (43%), Gaps = 10/186 (5%)
Query: 116 LQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADT----VAQITQRFYEAE 171
LQ GC++ P G + A+ GKD +S SW V Q + +
Sbjct: 114 LQVSAGCEVHP-GNASNNFFHVAFQGKDILSFQGT--SWEPTQEAPLWVNLAIQVLNQDK 170
Query: 172 EYAEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPI-SDHEATLRCWALGFY 230
E + L G C + + LE+GK L++ PKA ++ P L C GFY
Sbjct: 171 WTRETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFY 230
Query: 231 PAEITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLP-Q 289
P + + W R GE++ Q T+ + P D T+ A + V GE +C V+H L Q
Sbjct: 231 PKPVWVKWMR-GEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQ 289
Query: 290 PLILRW 295
++L W
Sbjct: 290 DIVLYW 295
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,236,031
Number of Sequences: 37866
Number of extensions: 868042
Number of successful extensions: 2280
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 94
Number of HSP's successfully gapped in prelim test: 47
Number of HSP's that attempted gapping in prelim test: 2064
Number of HSP's gapped (non-prelim): 170
length of query: 442
length of database: 18,247,518
effective HSP length: 105
effective length of query: 337
effective length of database: 14,271,588
effective search space: 4809525156
effective search space used: 4809525156
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.