Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 4504417
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504417 major histocompatibility complex, class I-related
[Homo sapiens]
(341 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504417 major histocompatibility complex, class I-related [Ho... 713 0.0
gi|24797067 major histocompatibility complex, class I, A precurs... 235 5e-62
gi|17986001 major histocompatibility complex, class I, B precurs... 233 2e-61
gi|4504415 major histocompatibility complex, class I, G precurso... 226 2e-59
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 226 2e-59
gi|62912479 major histocompatibility complex, class I, E precurs... 225 4e-59
gi|52630342 major histocompatibility complex, class I, C precurs... 224 1e-58
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 223 3e-58
gi|149158702 major histocompatibility complex, class I, F isofor... 222 4e-58
gi|149158698 major histocompatibility complex, class I, F isofor... 222 4e-58
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 207 1e-53
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 207 1e-53
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 182 5e-46
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 157 1e-38
gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H... 149 3e-36
gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom... 149 3e-36
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 142 6e-34
gi|149158700 major histocompatibility complex, class I, F isofor... 137 1e-32
gi|167857788 MHC class I polypeptide-related sequence B [Homo sa... 134 9e-32
gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi... 131 8e-31
gi|110618224 CD1A antigen precursor [Homo sapiens] 103 2e-22
gi|24797076 major histocompatibility complex, class II, DP beta ... 86 5e-17
gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s... 86 6e-17
gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa... 86 6e-17
gi|17986005 major histocompatibility complex, class II, DR beta ... 84 2e-16
gi|239740743 PREDICTED: similar to HLA class II histocompatibili... 84 2e-16
gi|239740693 PREDICTED: similar to HLA class II histocompatibili... 84 2e-16
gi|4502649 CD1D antigen precursor [Homo sapiens] 84 2e-16
gi|239740920 PREDICTED: similar to major histocompatibility comp... 81 2e-15
gi|239740918 PREDICTED: similar to major histocompatibility comp... 81 2e-15
>gi|4504417 major histocompatibility complex, class I-related [Homo
sapiens]
Length = 341
Score = 713 bits (1841), Expect = 0.0
Identities = 341/341 (100%), Positives = 341/341 (100%)
Query: 1 MGELMAFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS 60
MGELMAFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS
Sbjct: 1 MGELMAFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS 60
Query: 61 VTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGC 120
VTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGC
Sbjct: 61 VTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGC 120
Query: 121 ELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLE 180
ELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLE
Sbjct: 121 ELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLE 180
Query: 181 EECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNG 240
EECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNG
Sbjct: 181 EECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNG 240
Query: 241 EEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQESETIPL 300
EEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQESETIPL
Sbjct: 241 EEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQESETIPL 300
Query: 301 VMKAVSGSIVLVIVLAGVGVLVWRRRPREQNGAIYLPTPDR 341
VMKAVSGSIVLVIVLAGVGVLVWRRRPREQNGAIYLPTPDR
Sbjct: 301 VMKAVSGSIVLVIVLAGVGVLVWRRRPREQNGAIYLPTPDR 341
>gi|24797067 major histocompatibility complex, class I, A precursor
[Homo sapiens]
Length = 365
Score = 235 bits (599), Expect = 5e-62
Identities = 131/347 (37%), Positives = 200/347 (57%), Gaps = 19/347 (5%)
Query: 5 MAFLLPLIIVLMVKHSDSRT------HSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTY 58
MA + P ++L++ + + T HS+RYF VS P G P FI+VGYVD +
Sbjct: 1 MAVMAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRF 60
Query: 59 DS--VTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHS--GSHTY 114
DS +++ EPRAPW+ E P++W++ T+ ++ Q +V+L L+ +YN S GSHT
Sbjct: 61 DSDAASQRMEPRAPWI-EQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTI 119
Query: 115 QRMIGCELLEDGS-TTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELL 173
Q M GC++ DG G+ Q AYDG+D++ N+D SW A D A K+ WEA HE
Sbjct: 120 QIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEA-AHEAE 178
Query: 174 YQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIY 233
+ +L+ C+ WL+R+LE GK+TLQRT+PP + L C A GFYP EI
Sbjct: 179 QLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEIT 238
Query: 234 MTWMKNGEEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQ 293
+TW ++GE+ Q+ + + P+GDGT+Q WA++ + Y+CHV+H G+ L +
Sbjct: 239 LTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRW 298
Query: 294 E---SETIPLVMKAVSGSIVLVIVLAG--VGVLVWRRRPREQNGAIY 335
E TIP+V ++G ++L V+ G V ++WRR+ ++ G Y
Sbjct: 299 ELSSQPTIPIV-GIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSY 344
>gi|17986001 major histocompatibility complex, class I, B precursor
[Homo sapiens]
Length = 362
Score = 233 bits (593), Expect = 2e-61
Identities = 131/338 (38%), Positives = 191/338 (56%), Gaps = 13/338 (3%)
Query: 8 LLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS--VTRQK 65
LL L L + + + +HS+RYF VS P G P FISVGYVD +DS + ++
Sbjct: 10 LLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPRE 69
Query: 66 EPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHS--GSHTYQRMIGCELL 123
EPRAPW+ E P++W+R TQ+ + Q + L+ L+ +YN S GSHT Q M GC++
Sbjct: 70 EPRAPWI-EQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYGCDVG 128
Query: 124 EDGSTT-GFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEE 182
DG G QYAYDG+D++ N+D SW A D A ++ WEA + E ++ +LE E
Sbjct: 129 PDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAR-EAEQRRAYLEGE 187
Query: 183 CIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEE 242
C+ WL+R+LE GKD L+R +PP V L C A GFYP EI +TW ++GE+
Sbjct: 188 CVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGED 247
Query: 243 IVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQV---PQESETIP 299
Q+ + + P+GD T+Q WA++ + Y+CHV+H G+ L + P T+P
Sbjct: 248 QTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQSTVP 307
Query: 300 LVMKAVSGSIVLVIVLAG--VGVLVWRRRPREQNGAIY 335
+V V+G VL +V+ G V ++ RR+ G Y
Sbjct: 308 IV-GIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSY 344
>gi|4504415 major histocompatibility complex, class I, G precursor
[Homo sapiens]
Length = 338
Score = 226 bits (577), Expect = 2e-59
Identities = 122/312 (39%), Positives = 181/312 (58%), Gaps = 11/312 (3%)
Query: 24 THSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTR--QKEPRAPWMAENLAPDHW 81
+HS+RYF VS P G P FI++GYVD +DS + + EPRAPW+ E P++W
Sbjct: 26 SHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSDSACPRMEPRAPWV-EQEGPEYW 84
Query: 82 ERYTQLLRGWQQMFKVELKRLQRHYNHS--GSHTYQRMIGCELLEDGSTT-GFLQYAYDG 138
E T+ + Q ++ L+ L+ +YN S SHT Q MIGC+L DG G+ QYAYDG
Sbjct: 85 EEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQWMIGCDLGSDGRLLRGYEQYAYDG 144
Query: 139 QDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKRFLEYGKDTL 198
+D+L N+D SW A D A K+ EA + ++ +LE C+ WL R+LE GK+ L
Sbjct: 145 KDYLALNEDLRSWTAADTAAQISKRKCEA-ANVAEQRRAYLEGTCVEWLHRYLENGKEML 203
Query: 199 QRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEIVQEIDYGDILPSGDG 258
QR +PP V F L C A GFYP EI +TW ++GE+ Q+++ + P+GDG
Sbjct: 204 QRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILTWQRDGEDQTQDVELVETRPAGDG 263
Query: 259 TYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQESETIPL--VMKAVSGSIVLVIVLA 316
T+Q WA++ + Y+CHV+H G+ L + + ++P +M V+G +VL V+
Sbjct: 264 TFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSSLPTIPIMGIVAGLVVLAAVVT 323
Query: 317 G--VGVLVWRRR 326
G V ++WR++
Sbjct: 324 GAAVAAVLWRKK 335
>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
sapiens]
Length = 366
Score = 226 bits (577), Expect = 2e-59
Identities = 126/315 (40%), Positives = 180/315 (57%), Gaps = 9/315 (2%)
Query: 24 THSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS--VTRQKEPRAPWMAENLAPDHW 81
+HSLRYF VS P G P FISVGYVD +DS ++EPRAPWM E P++W
Sbjct: 39 SHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWM-EQEGPEYW 97
Query: 82 ERYTQLLRGWQQMFKVELKRLQRHYNHS--GSHTYQRMIGCELLEDGS-TTGFLQYAYDG 138
+ T++++ Q F+V L L+ +YN S GSHT Q M GC++ DG GF+Q AYDG
Sbjct: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDG 157
Query: 139 QDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKRFLEYGKDTL 198
+D++ N+D SW A D A K+ EA Q+N+LE C+ L+R+LE GKD L
Sbjct: 158 RDYIALNEDLRSWTAADTAAQITKRKREA-AGAAERQRNYLEGRCVEGLRRYLETGKDAL 216
Query: 199 QRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEIVQEIDYGDILPSGDG 258
R +PP V L C A GFYP EI +TW + GE+ Q+++ + PSGDG
Sbjct: 217 LRADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDG 276
Query: 259 TYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQE-SETIPLVMKAVSGSIVLVIVLAG 317
T+Q WA++ + Y+C V+H G+ L + E +T L+M + G ++LV+ L
Sbjct: 277 TFQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWEPPQTSFLIMGIIVGLVLLVVALV- 335
Query: 318 VGVLVWRRRPREQNG 332
G ++WR++ + G
Sbjct: 336 AGAVIWRKKRSGREG 350
>gi|62912479 major histocompatibility complex, class I, E precursor
[Homo sapiens]
Length = 358
Score = 225 bits (574), Expect = 4e-59
Identities = 130/338 (38%), Positives = 190/338 (56%), Gaps = 13/338 (3%)
Query: 8 LLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS--VTRQK 65
LL L L + + + +HSL+YF VS P G P FISVGYVD +D+ + +
Sbjct: 7 LLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRM 66
Query: 66 EPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHS--GSHTYQRMIGCELL 123
PRAPWM E ++W+R T+ R Q+F+V L+ L+ +YN S GSHT Q M GCEL
Sbjct: 67 VPRAPWM-EQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGCELG 125
Query: 124 EDGS-TTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEE 182
DG G+ Q+AYDG+D+L N+D SW AVD A +Q + E +Q+ +LE+
Sbjct: 126 PDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQK-SNDASEAEHQRAYLEDT 184
Query: 183 CIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEE 242
C+ WL ++LE GK+TL EPP V L C A GFYP EI +TW ++GE
Sbjct: 185 CVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGEG 244
Query: 243 IVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQV---PQESETIP 299
Q+ + + P+GDGT+Q WA++ + Y+CHV+H G+ + + P TIP
Sbjct: 245 HTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQPTIP 304
Query: 300 LVMKAVSGSIVLVIVLAG--VGVLVWRRRPREQNGAIY 335
+V ++G ++L V++G V ++WR++ G Y
Sbjct: 305 IV-GIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSY 341
>gi|52630342 major histocompatibility complex, class I, C precursor
[Homo sapiens]
Length = 366
Score = 224 bits (570), Expect = 1e-58
Identities = 135/326 (41%), Positives = 188/326 (57%), Gaps = 14/326 (4%)
Query: 6 AFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS--VTR 63
A LL L L + + + +HS+RYF VS P G P FISVGYVD +DS +
Sbjct: 8 ALLLLLSGGLALTETWACSHSMRYFDTAVSRPGRGEPRFISVGYVDDTQFVRFDSDAASP 67
Query: 64 QKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHS--GSHTYQRMIGCE 121
+ EPRAPW+ E P++W+R TQ + Q +V L+ L+ +YN S GSHT QRM GC+
Sbjct: 68 RGEPRAPWV-EQEGPEYWDRETQKYKRQAQADRVSLRNLRGYYNQSEDGSHTLQRMSGCD 126
Query: 122 LLEDGSTT-GFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQH-ELLYQKNWL 179
L DG G+ Q AYDG+D++ N+D SW A D A ++ EA + E L + +L
Sbjct: 127 LGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAARAAEQL--RAYL 184
Query: 180 EEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKN 239
E C+ WL+R+LE GK+TLQR EPP V L C A GFYP EI +TW ++
Sbjct: 185 EGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPAEITLTWQRD 244
Query: 240 GEEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQV---PQESE 296
GE+ Q+ + + P+GDGT+Q WA++ + Y+CH++H G+ L + P
Sbjct: 245 GEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQEPLTLSWEPSSQP 304
Query: 297 TIPLVMKAVSGSIVLVIVLAGVGVLV 322
TIP +M V+G VLV VLA +G +V
Sbjct: 305 TIP-IMGIVAGLAVLV-VLAVLGAVV 328
>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
sapiens]
Length = 348
Score = 223 bits (567), Expect = 3e-58
Identities = 122/323 (37%), Positives = 185/323 (57%), Gaps = 5/323 (1%)
Query: 8 LLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTRQKEP 67
LL L+ +++ R+HSL Y +G S+ G+ F ++GYVD YD +R+ EP
Sbjct: 11 LLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEP 70
Query: 68 RAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSG-SHTYQRMIGCELLEDG 126
R PW++ ++ W + +Q L+GW MF V+ + ++NHS SHT Q ++GCE+ ED
Sbjct: 71 RTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDN 130
Query: 127 STTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAW 186
ST G+ +Y YDGQD L F DTL W A + A K WE ++ + +LE +C A
Sbjct: 131 STEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQ 190
Query: 187 LKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEI-VQ 245
L++ LE G+ L + PPLV+V T VT L C+A +YP I M W+K+ + + +
Sbjct: 191 LQQLLELGRGVLDQQVPPLVKVTHHVT-SSVTTLRCRALNYYPQNITMKWLKDKQPMDAK 249
Query: 246 EIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQE-SETIPLVMKA 304
E + D+LP+GDGTYQ W ++ + P Y+C VEH G+ L V E S + LV+
Sbjct: 250 EFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGV 309
Query: 305 VSGSIVLVIVL-AGVGVLVWRRR 326
+SG V V++L G+ ++ R+R
Sbjct: 310 ISGIAVFVVILFIGILFIILRKR 332
>gi|149158702 major histocompatibility complex, class I, F isoform 1
precursor [Homo sapiens]
Length = 442
Score = 222 bits (565), Expect = 4e-58
Identities = 133/342 (38%), Positives = 192/342 (56%), Gaps = 17/342 (4%)
Query: 6 AFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS--VTR 63
+ LL L L + + + +HSLRYF VS P G P +I+V YVD +DS
Sbjct: 5 SLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIP 64
Query: 64 QKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHS--GSHTYQRMIGCE 121
+ EPR PW+ E P +WE T + Q +V L+ L R YN S GSHT Q M GC+
Sbjct: 65 RMEPREPWV-EQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCD 123
Query: 122 LLEDGSTT-GFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLE 180
+ DG G+ Q+AYDG+D++ N+D SW A D VA ++ +EA ++ + + +LE
Sbjct: 124 MGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEF-RTYLE 182
Query: 181 EECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNG 240
EC+ L+R+LE GK+TLQR +PP V L C A GFYP EI +TW ++G
Sbjct: 183 GECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDG 242
Query: 241 EEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVL-----QVPQES 295
EE Q+ + + P+GDGT+Q WA++ + P Y+CHV+H G+ L Q PQ
Sbjct: 243 EEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ-- 300
Query: 296 ETIPLVMKAVSGSIVLVIVLAG--VGVLVWRRRPREQNGAIY 335
TIP+V V+G +VL V+ G V ++WR++ ++N Y
Sbjct: 301 PTIPIV-GIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSY 341
>gi|149158698 major histocompatibility complex, class I, F isoform 2
precursor [Homo sapiens]
Length = 346
Score = 222 bits (565), Expect = 4e-58
Identities = 133/342 (38%), Positives = 192/342 (56%), Gaps = 17/342 (4%)
Query: 6 AFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS--VTR 63
+ LL L L + + + +HSLRYF VS P G P +I+V YVD +DS
Sbjct: 5 SLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIP 64
Query: 64 QKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHS--GSHTYQRMIGCE 121
+ EPR PW+ E P +WE T + Q +V L+ L R YN S GSHT Q M GC+
Sbjct: 65 RMEPREPWV-EQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCD 123
Query: 122 LLEDGSTT-GFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLE 180
+ DG G+ Q+AYDG+D++ N+D SW A D VA ++ +EA ++ + + +LE
Sbjct: 124 MGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEF-RTYLE 182
Query: 181 EECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNG 240
EC+ L+R+LE GK+TLQR +PP V L C A GFYP EI +TW ++G
Sbjct: 183 GECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDG 242
Query: 241 EEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVL-----QVPQES 295
EE Q+ + + P+GDGT+Q WA++ + P Y+CHV+H G+ L Q PQ
Sbjct: 243 EEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ-- 300
Query: 296 ETIPLVMKAVSGSIVLVIVLAG--VGVLVWRRRPREQNGAIY 335
TIP+V V+G +VL V+ G V ++WR++ ++N Y
Sbjct: 301 PTIPIV-GIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSY 341
>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
sapiens]
Length = 325
Score = 207 bits (526), Expect = 1e-53
Identities = 110/286 (38%), Positives = 165/286 (57%), Gaps = 5/286 (1%)
Query: 45 ISVGYVDSHPITTYDSVTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQR 104
+ +GYVD YD +R+ EPR PW++ ++ W + +Q L+GW MF V+ +
Sbjct: 25 LPLGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIME 84
Query: 105 HYNHSG-SHTYQRMIGCELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQ 163
++NHS SHT Q ++GCE+ ED ST G+ +Y YDGQD L F DTL W A + A K
Sbjct: 85 NHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKL 144
Query: 164 AWEANQHELLYQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCK 223
WE ++ + +LE +C A L++ LE G+ L + PPLV+V T VT L C+
Sbjct: 145 EWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVT-SSVTTLRCR 203
Query: 224 AHGFYPPEIYMTWMKNGEEI-VQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEH 282
A +YP I M W+K+ + + +E + D+LP+GDGTYQ W ++ + P Y+C VEH
Sbjct: 204 ALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEH 263
Query: 283 CGVHMVLQVPQE-SETIPLVMKAVSGSIVLVIVL-AGVGVLVWRRR 326
G+ L V E S + LV+ +SG V V++L G+ ++ R+R
Sbjct: 264 PGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 309
>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
sapiens]
Length = 334
Score = 207 bits (526), Expect = 1e-53
Identities = 116/323 (35%), Positives = 178/323 (55%), Gaps = 19/323 (5%)
Query: 8 LLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTRQKEP 67
LL L+ +++ R+HSL Y +G S+ G+ F ++GYVD YD +R+ EP
Sbjct: 11 LLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEP 70
Query: 68 RAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSG-SHTYQRMIGCELLEDG 126
R PW++ ++ W + +Q L+GW MF V+ + ++NHS SHT Q ++GCE+ ED
Sbjct: 71 RTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDN 130
Query: 127 STTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAW 186
ST G+ +Y YDGQD L F DTL W A + A K WE ++ + +LE +C A
Sbjct: 131 STEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQ 190
Query: 187 LKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEI-VQ 245
L++ LE G+ L + VT L C+A +YP I M W+K+ + + +
Sbjct: 191 LQQLLELGRGVLDQQ---------------VTTLRCRALNYYPQNITMKWLKDKQPMDAK 235
Query: 246 EIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQE-SETIPLVMKA 304
E + D+LP+GDGTYQ W ++ + P Y+C VEH G+ L V E S + LV+
Sbjct: 236 EFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGV 295
Query: 305 VSGSIVLVIVL-AGVGVLVWRRR 326
+SG V V++L G+ ++ R+R
Sbjct: 296 ISGIAVFVVILFIGILFIILRKR 318
>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
Length = 298
Score = 182 bits (461), Expect = 5e-46
Identities = 106/294 (36%), Positives = 163/294 (55%), Gaps = 6/294 (2%)
Query: 4 LMAFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTR 63
L++ LL L + ++ D R +SL Y G+S + VP F ++G ++ Y+S R
Sbjct: 8 LLSLLLLLGPAVPQENQDGR-YSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDR 66
Query: 64 QKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHS-GSHTYQRMIGCEL 122
+ +P W D W++ +QL + + +F LK + +YN S GSH Q GCE+
Sbjct: 67 KSQPMGLWRQVEGMED-WKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQGRFGCEI 125
Query: 123 LEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEE 182
+ S+ F +Y YDG+D++ FNK+ +W+ D A KQ WEA + K +LEEE
Sbjct: 126 ENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYLEEE 185
Query: 183 CIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEE 242
C A L+++L+Y K+ L R +PP V V + L C A+ FYP +I + W + GE
Sbjct: 186 CPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGE- 244
Query: 243 IVQEIDY-GDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQES 295
VQE + GD+L +G+GTYQ+W + + PQ + YSCHV+H + L VP E+
Sbjct: 245 -VQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEA 297
>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
sapiens]
Length = 260
Score = 157 bits (398), Expect = 1e-38
Identities = 87/219 (39%), Positives = 127/219 (57%), Gaps = 4/219 (1%)
Query: 111 SHTYQRMIGCELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQH 170
SHT Q ++GCE+ ED ST G+ +Y YDGQD L F DTL W A + A K WE ++
Sbjct: 27 SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKI 86
Query: 171 ELLYQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPP 230
+ +LE +C A L++ LE G+ L + PPLV+V T VT L C+A +YP
Sbjct: 87 RARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVT-SSVTTLRCRALNYYPQ 145
Query: 231 EIYMTWMKNGEEI-VQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVL 289
I M W+K+ + + +E + D+LP+GDGTYQ W ++ + P Y+C VEH G+ L
Sbjct: 146 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 205
Query: 290 QVPQE-SETIPLVMKAVSGSIVLVIVL-AGVGVLVWRRR 326
V E S + LV+ +SG V V++L G+ ++ R+R
Sbjct: 206 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 244
>gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 149 bits (377), Expect = 3e-36
Identities = 101/344 (29%), Positives = 166/344 (48%), Gaps = 20/344 (5%)
Query: 9 LPLIIVLMVKHSDSRTH-SLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTRQKEP 67
L L++ L+ + +H SL Y VS P G P F G++ +Y+S+ + EP
Sbjct: 11 LGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEP 70
Query: 68 RAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGCELLEDGS 127
W+ EN +WE+ T LR +++F K L G +T Q ++GCEL D +
Sbjct: 71 CGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKAL----GGKGPYTLQGLLGCELGPDNT 126
Query: 128 TTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAWL 187
+ ++A +G++F+ F+ +W A I Q W+ + +L C L
Sbjct: 127 SVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRL 186
Query: 188 KRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEIVQEI 247
+ LE G+ L+ EPP +R+ + + PG + L C A FYPPE+ + +++NG +
Sbjct: 187 REHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNG--LAAGT 244
Query: 248 DYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQES--ETIPLVMKAV 305
GD P+ DG++ A +S+ + + Y C V+H G+ L+V ES ++ LV+ V
Sbjct: 245 GQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIV 304
Query: 306 SGSIVLVIVLAGVGVLVWRRRP----------REQNGAIYLPTP 339
G ++L G G L+WRR R + + LPTP
Sbjct: 305 IGVLLLTAAAVG-GALLWRRMRSGLPAPWISLRGDDTGVLLPTP 347
>gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 149 bits (377), Expect = 3e-36
Identities = 101/344 (29%), Positives = 166/344 (48%), Gaps = 20/344 (5%)
Query: 9 LPLIIVLMVKHSDSRTH-SLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTRQKEP 67
L L++ L+ + +H SL Y VS P G P F G++ +Y+S+ + EP
Sbjct: 11 LGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEP 70
Query: 68 RAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGCELLEDGS 127
W+ EN +WE+ T LR +++F K L G +T Q ++GCEL D +
Sbjct: 71 CGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKAL----GGKGPYTLQGLLGCELGPDNT 126
Query: 128 TTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAWL 187
+ ++A +G++F+ F+ +W A I Q W+ + +L C L
Sbjct: 127 SVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRL 186
Query: 188 KRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEIVQEI 247
+ LE G+ L+ EPP +R+ + + PG + L C A FYPPE+ + +++NG +
Sbjct: 187 REHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNG--LAAGT 244
Query: 248 DYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQES--ETIPLVMKAV 305
GD P+ DG++ A +S+ + + Y C V+H G+ L+V ES ++ LV+ V
Sbjct: 245 GQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIV 304
Query: 306 SGSIVLVIVLAGVGVLVWRRRP----------REQNGAIYLPTP 339
G ++L G G L+WRR R + + LPTP
Sbjct: 305 IGVLLLTAAAVG-GALLWRRMRSGLPAPWISLRGDDTGVLLPTP 347
>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
sapiens]
Length = 246
Score = 142 bits (357), Expect = 6e-34
Identities = 81/219 (36%), Positives = 120/219 (54%), Gaps = 18/219 (8%)
Query: 111 SHTYQRMIGCELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQH 170
SHT Q ++GCE+ ED ST G+ +Y YDGQD L F DTL W A + A K WE ++
Sbjct: 27 SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKI 86
Query: 171 ELLYQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPP 230
+ +LE +C A L++ LE G+ L + VT L C+A +YP
Sbjct: 87 RARQNRAYLERDCPAQLQQLLELGRGVLDQQ---------------VTTLRCRALNYYPQ 131
Query: 231 EIYMTWMKNGEEI-VQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVL 289
I M W+K+ + + +E + D+LP+GDGTYQ W ++ + P Y+C VEH G+ L
Sbjct: 132 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 191
Query: 290 QVPQE-SETIPLVMKAVSGSIVLVIVL-AGVGVLVWRRR 326
V E S + LV+ +SG V V++L G+ ++ R+R
Sbjct: 192 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 230
>gi|149158700 major histocompatibility complex, class I, F isoform 3
precursor [Homo sapiens]
Length = 254
Score = 137 bits (345), Expect = 1e-32
Identities = 82/202 (40%), Positives = 116/202 (57%), Gaps = 7/202 (3%)
Query: 6 AFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS--VTR 63
+ LL L L + + + +HSLRYF VS P G P +I+V YVD +DS
Sbjct: 5 SLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIP 64
Query: 64 QKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHS--GSHTYQRMIGCE 121
+ EPR PW+ E P +WE T + Q +V L+ L R YN S GSHT Q M GC+
Sbjct: 65 RMEPREPWV-EQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCD 123
Query: 122 LLEDGSTT-GFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLE 180
+ DG G+ Q+AYDG+D++ N+D SW A D VA ++ +EA ++ + + +LE
Sbjct: 124 MGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEF-RTYLE 182
Query: 181 EECIAWLKRFLEYGKDTLQRTE 202
EC+ L+R+LE GK+TLQR E
Sbjct: 183 GECLELLRRYLENGKETLQRAE 204
>gi|167857788 MHC class I polypeptide-related sequence B [Homo
sapiens]
Length = 383
Score = 134 bits (338), Expect = 9e-32
Identities = 85/306 (27%), Positives = 141/306 (46%), Gaps = 21/306 (6%)
Query: 25 HSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTRQKEPRAPWMAENLAPDHWERY 84
HSLRY + +S F++ G++D P YD R+ +P+ W L W+
Sbjct: 26 HSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTWDTE 85
Query: 85 TQLLRGWQQMFKVELKRLQRHYNHS--GSHTYQRMIGCELLEDGSTTGFLQYAYDGQDFL 142
T+ L Q +L+R H G H+ Q + CE+ ED ST G + YDG+ FL
Sbjct: 86 TEDLTENGQ----DLRRTLTHIKDQKGGLHSLQEIRVCEIHEDSSTRGSRHFYYDGELFL 141
Query: 143 IFNKDTLSWLA-----VDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKRFLEYGKDT 197
N +T +A + W+ + + ++ +C+ L+R+L+ G
Sbjct: 142 SQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSGV-A 200
Query: 198 LQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEIVQEID-YGDILPSG 256
++RT PP+V V E G + C+A FYP I +TW ++G + +GD+LP G
Sbjct: 201 IRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDG 260
Query: 257 DGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVP--------QESETIPLVMKAVSGS 308
+GTYQ W + + ++C++EH G H VP + P V A+
Sbjct: 261 NGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKALVLQSQRTDFPYVSAAMPCF 320
Query: 309 IVLVIV 314
++++I+
Sbjct: 321 VIIIIL 326
>gi|4557751 MHC class I polypeptide-related sequence A [Homo
sapiens]
Length = 383
Score = 131 bits (330), Expect = 8e-31
Identities = 83/303 (27%), Positives = 144/303 (47%), Gaps = 15/303 (4%)
Query: 25 HSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTRQKEPRAPWMAENLAPDHWERY 84
HSLRY +S F++ ++D P D + +P+ W + L W+R
Sbjct: 26 HSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQKCRAKPQGQWAEDVLGNKTWDRE 85
Query: 85 TQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGCELLEDGSTTGFLQYAYDGQDFLIF 144
T+ L G + ++ L ++ G H+ Q + CE+ ED ST + YDG+ FL
Sbjct: 86 TRDLTGNGKDLRMTLAHIKDQ--KEGLHSLQEIRVCEIHEDNSTRSSQHFYYDGELFLSQ 143
Query: 145 NKDTLSWLA-----VDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKRFLEYGKDTLQ 199
N +T W +A ++ + + + + + +C+ L+R+L+ G L+
Sbjct: 144 NLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADCLQELRRYLKSGV-VLR 202
Query: 200 RTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEIVQEID-YGDILPSGDG 258
RT PP+V V R E G + C+A GFYP I ++W ++G + + +GD+LP G+G
Sbjct: 203 RTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWRQDGVSLSHDTQQWGDVLPDGNG 262
Query: 259 TYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQ------ESETIPLVMKAVSGSIVLV 312
TYQ W + + ++C++EH G H VP +S + AV+ + + V
Sbjct: 263 TYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKVLVLQSHWQTFHVSAVAAAAIFV 322
Query: 313 IVL 315
I++
Sbjct: 323 III 325
>gi|110618224 CD1A antigen precursor [Homo sapiens]
Length = 327
Score = 103 bits (257), Expect = 2e-22
Identities = 93/334 (27%), Positives = 145/334 (43%), Gaps = 22/334 (6%)
Query: 4 LMAFLLPLIIVLMVK-HSDSRTHSLRYFRLGVSDPI-HGVPEFISVGYVDSHPITTYDSV 61
++ LLPL+ VL ++D L + ++ H + + G++ T+DS
Sbjct: 1 MLFLLLPLLAVLPGDGNADGLKEPLSFHVTWIASFYNHSWKQNLVSGWLSDLQTHTWDSN 60
Query: 62 TRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMI--- 118
+ PW N + + W+ L R + + R Y H Y I
Sbjct: 61 SSTIVFLCPWSRGNFSNEEWKELETLFR----IRTIRSFEGIRRYAHELQFEYPFEIQVT 116
Query: 119 -GCELLEDGSTTGFLQYAYDGQDFLIF-NKDTLSWLAVDNVAHTIKQAWEANQHELLYQK 176
GCEL + FLQ AY G DF+ F N L + N+A + NQHE
Sbjct: 117 GGCELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITH 176
Query: 177 NWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKET-FPGVTALFCKAHGFYPPEIYMT 235
N L + C ++ L+ GK LQR P ++ + PG L C GFYP +++
Sbjct: 177 NLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVM 236
Query: 236 WMKNGEEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHC---GVHMVLQVP 292
WM+ GE+ Q GDILPS DGT+ A++E+ + SC V+H G +VL
Sbjct: 237 WMR-GEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWE 295
Query: 293 QESETIPLVMKAVSGSIVLVIVLAGVGVLVWRRR 326
S +++ V+V +L +G+ +W R+
Sbjct: 296 HHSSVGFIIL------AVIVPLLLLIGLALWFRK 323
>gi|24797076 major histocompatibility complex, class II, DP beta 1
precursor [Homo sapiens]
Length = 258
Score = 85.9 bits (211), Expect = 5e-17
Identities = 57/211 (27%), Positives = 103/211 (48%), Gaps = 8/211 (3%)
Query: 128 TTGFLQ-YAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAW 186
T FL+ Y Y+ ++F F+ D + AV + + W + Q ++L +K + +
Sbjct: 50 TQRFLERYIYNREEFARFDSDVGEFRAVTELGRPAAEYWNS-QKDILEEKRAVPDRMCR- 107
Query: 187 LKRFLEYGKDTLQRTEPPLVRVN--RKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEIV 244
+ G TLQR P V V+ +K L C FYP I + W NG+E
Sbjct: 108 -HNYELGGPMTLQRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEET 166
Query: 245 QEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQESETIPLVMKA 304
+ +++ +GD T+Q +E+ PQ ++Y+C VEH + + V ++++ K
Sbjct: 167 AGVVSTNLIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKT 226
Query: 305 VSGS--IVLVIVLAGVGVLVWRRRPREQNGA 333
++G+ VL +++ GVG+ + RR + Q G+
Sbjct: 227 LTGAGGFVLGLIICGVGIFMHRRSKKVQRGS 257
>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
sapiens]
Length = 168
Score = 85.5 bits (210), Expect = 6e-17
Identities = 49/127 (38%), Positives = 74/127 (58%), Gaps = 4/127 (3%)
Query: 203 PPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEI-VQEIDYGDILPSGDGTYQ 261
PPLV+V T VT L C+A +YP I M W+K+ + + +E + D+LP+GDGTYQ
Sbjct: 27 PPLVKVTHHVT-SSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85
Query: 262 AWASIELDPQSSNLYSCHVEHCGVHMVLQVPQE-SETIPLVMKAVSGSIVLVIVL-AGVG 319
W ++ + P Y+C VEH G+ L V E S + LV+ +SG V V++L G+
Sbjct: 86 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 145
Query: 320 VLVWRRR 326
++ R+R
Sbjct: 146 FIILRKR 152
>gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
sapiens]
Length = 256
Score = 85.5 bits (210), Expect = 6e-17
Identities = 49/127 (38%), Positives = 74/127 (58%), Gaps = 4/127 (3%)
Query: 203 PPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEI-VQEIDYGDILPSGDGTYQ 261
PPLV+V T VT L C+A +YP I M W+K+ + + +E + D+LP+GDGTYQ
Sbjct: 115 PPLVKVTHHVT-SSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 173
Query: 262 AWASIELDPQSSNLYSCHVEHCGVHMVLQVPQE-SETIPLVMKAVSGSIVLVIVL-AGVG 319
W ++ + P Y+C VEH G+ L V E S + LV+ +SG V V++L G+
Sbjct: 174 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 233
Query: 320 VLVWRRR 326
++ R+R
Sbjct: 234 FIILRKR 240
Score = 75.1 bits (183), Expect = 8e-14
Identities = 35/102 (34%), Positives = 58/102 (56%)
Query: 8 LLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTRQKEP 67
LL L+ +++ R+HSL Y +G S+ G+ F ++GYVD YD +R+ EP
Sbjct: 11 LLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEP 70
Query: 68 RAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHS 109
R PW++ ++ W + +Q L+GW MF V+ + ++NHS
Sbjct: 71 RTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHS 112
>gi|17986005 major histocompatibility complex, class II, DR beta 3
precursor [Homo sapiens]
Length = 266
Score = 83.6 bits (205), Expect = 2e-16
Identities = 58/205 (28%), Positives = 98/205 (47%), Gaps = 9/205 (4%)
Query: 133 QYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKRFLE 192
+Y ++ ++FL F+ D + AV + + ++W + Q +LL QK + + +
Sbjct: 58 RYFHNQEEFLRFDSDVGEYRAVTELGRPVAESWNS-QKDLLEQKRGRVDN---YCRHNYG 113
Query: 193 YGKD-TLQRTEPPLVRVNRKETFP--GVTALFCKAHGFYPPEIYMTWMKNGEEIVQEIDY 249
G+ T+QR P V V +T P L C GFYP I + W +NG+E +
Sbjct: 114 VGESFTVQRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVS 173
Query: 250 GDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVP--QESETIPLVMKAVSG 307
++ +GD T+Q +E P+S +Y+C VEH V L V SE+ M + G
Sbjct: 174 TGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVG 233
Query: 308 SIVLVIVLAGVGVLVWRRRPREQNG 332
VL ++ G G+ ++ R + +G
Sbjct: 234 GFVLGLLFLGAGLFIYFRNQKGHSG 258
>gi|239740743 PREDICTED: similar to HLA class II histocompatibility
antigen, DRB1-7 beta chain isoform 2 [Homo sapiens]
Length = 264
Score = 83.6 bits (205), Expect = 2e-16
Identities = 61/249 (24%), Positives = 111/249 (44%), Gaps = 10/249 (4%)
Query: 90 GWQQMFKVELKRLQRHYNHSGSHTYQRMIGCELLEDGSTTGFLQYA-YDGQDFLIFNKDT 148
G Q+ + L++ +++ +Q C FL+ Y+ ++F+ F+ D
Sbjct: 12 GQQRRLRKSPGMLEKREHNASRFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDV 71
Query: 149 LSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKRFLEYGKD-TLQRTEPPLVR 207
+ AV + + ++W + + L ++ ++ C + G+ T+QR P V
Sbjct: 72 GEYRAVTELGRPVAESWNSQKDILEDRRGQVDTVC----RHNYGVGESFTVQRRVHPEVT 127
Query: 208 VNRKETFP--GVTALFCKAHGFYPPEIYMTWMKNGEEIVQEIDYGDILPSGDGTYQAWAS 265
V +T P L C GFYP I + W +NG+E + ++ +GD T+Q
Sbjct: 128 VYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVM 187
Query: 266 IELDPQSSNLYSCHVEHCGVHMVLQVP--QESETIPLVMKAVSGSIVLVIVLAGVGVLVW 323
+E P+S +Y+C VEH V L V SE+ M + G VL ++ G G+ ++
Sbjct: 188 LETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIY 247
Query: 324 RRRPREQNG 332
R + +G
Sbjct: 248 FRNQKGHSG 256
>gi|239740693 PREDICTED: similar to HLA class II histocompatibility
antigen, DRB1-7 beta chain isoform 2 [Homo sapiens]
Length = 264
Score = 83.6 bits (205), Expect = 2e-16
Identities = 61/249 (24%), Positives = 111/249 (44%), Gaps = 10/249 (4%)
Query: 90 GWQQMFKVELKRLQRHYNHSGSHTYQRMIGCELLEDGSTTGFLQYA-YDGQDFLIFNKDT 148
G Q+ + L++ +++ +Q C FL+ Y+ ++F+ F+ D
Sbjct: 12 GQQRRLRKSPGMLEKREHNASRFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDV 71
Query: 149 LSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKRFLEYGKD-TLQRTEPPLVR 207
+ AV + + ++W + + L ++ ++ C + G+ T+QR P V
Sbjct: 72 GEYRAVTELGRPVAESWNSQKDILEDRRGQVDTVC----RHNYGVGESFTVQRRVHPEVT 127
Query: 208 VNRKETFP--GVTALFCKAHGFYPPEIYMTWMKNGEEIVQEIDYGDILPSGDGTYQAWAS 265
V +T P L C GFYP I + W +NG+E + ++ +GD T+Q
Sbjct: 128 VYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVM 187
Query: 266 IELDPQSSNLYSCHVEHCGVHMVLQVP--QESETIPLVMKAVSGSIVLVIVLAGVGVLVW 323
+E P+S +Y+C VEH V L V SE+ M + G VL ++ G G+ ++
Sbjct: 188 LETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIY 247
Query: 324 RRRPREQNG 332
R + +G
Sbjct: 248 FRNQKGHSG 256
>gi|4502649 CD1D antigen precursor [Homo sapiens]
Length = 335
Score = 83.6 bits (205), Expect = 2e-16
Identities = 64/258 (24%), Positives = 107/258 (41%), Gaps = 20/258 (7%)
Query: 70 PWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGCELLEDGSTT 129
PW + WE + R ++ F ++K + S Q GCE+ ++
Sbjct: 70 PWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLELQVSAGCEVHPGNASN 129
Query: 130 GFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEE-------- 181
F A+ G+D L F SW W ++L Q W E
Sbjct: 130 NFFHVAFQGKDILSF--QGTSWEPTQEA-----PLWVNLAIQVLNQDKWTRETVQWLLNG 182
Query: 182 ECIAWLKRFLEYGKDTLQRTEPPLVRVNR-KETFPGVTALFCKAHGFYPPEIYMTWMKNG 240
C ++ LE GK L++ P ++R PG L C GFYP +++ WM+ G
Sbjct: 183 TCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWVKWMR-G 241
Query: 241 EEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHC---GVHMVLQVPQESET 297
E+ Q GDILP+ D T+ A++++ + SC V+H G +VL +
Sbjct: 242 EQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVLYWGGSYTS 301
Query: 298 IPLVMKAVSGSIVLVIVL 315
+ L+ AV ++ ++++
Sbjct: 302 MGLIALAVLACLLFLLIV 319
>gi|239740920 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 2 [Homo sapiens]
Length = 261
Score = 80.9 bits (198), Expect = 2e-15
Identities = 51/200 (25%), Positives = 96/200 (48%), Gaps = 7/200 (3%)
Query: 130 GFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKR 189
G +Y Y+ +++ F+ D + AV + + W + + L + L+ C +
Sbjct: 58 GVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQL 117
Query: 190 FLEYGKDTLQRTEPPLVRVN--RKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEIVQEI 247
L + TLQR P V ++ R E L C FYP +I + W +N +E +
Sbjct: 118 EL---RTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGV 174
Query: 248 DYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVH--MVLQVPQESETIPLVMKAV 305
++ +GD T+Q +E+ PQ ++Y+CHVEH + ++++ +SE+ M +
Sbjct: 175 VSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKMLSG 234
Query: 306 SGSIVLVIVLAGVGVLVWRR 325
G VL ++ G+G+++ R
Sbjct: 235 IGGFVLGLIFLGLGLIIHHR 254
>gi|239740918 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 1 [Homo sapiens]
Length = 281
Score = 80.9 bits (198), Expect = 2e-15
Identities = 51/200 (25%), Positives = 96/200 (48%), Gaps = 7/200 (3%)
Query: 130 GFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKR 189
G +Y Y+ +++ F+ D + AV + + W + + L + L+ C +
Sbjct: 58 GVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQL 117
Query: 190 FLEYGKDTLQRTEPPLVRVN--RKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEIVQEI 247
L + TLQR P V ++ R E L C FYP +I + W +N +E +
Sbjct: 118 EL---RTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGV 174
Query: 248 DYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVH--MVLQVPQESETIPLVMKAV 305
++ +GD T+Q +E+ PQ ++Y+CHVEH + ++++ +SE+ M +
Sbjct: 175 VSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKMLSG 234
Query: 306 SGSIVLVIVLAGVGVLVWRR 325
G VL ++ G+G+++ R
Sbjct: 235 IGGFVLGLIFLGLGLIIHHR 254
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.437
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,518,447
Number of Sequences: 37866
Number of extensions: 666584
Number of successful extensions: 1768
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 96
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 1530
Number of HSP's gapped (non-prelim): 170
length of query: 341
length of database: 18,247,518
effective HSP length: 103
effective length of query: 238
effective length of database: 14,347,320
effective search space: 3414662160
effective search space used: 3414662160
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.