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Search of human proteins with 4502645
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502645 CD1B antigen precursor [Homo sapiens]
(333 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502645 CD1B antigen precursor [Homo sapiens] 688 0.0
gi|110618227 CD1C antigen precursor [Homo sapiens] 402 e-112
gi|110618224 CD1A antigen precursor [Homo sapiens] 394 e-110
gi|110618240 CD1E antigen isoform a precursor [Homo sapiens] 358 4e-99
gi|110618230 CD1E antigen isoform b precursor [Homo sapiens] 356 2e-98
gi|4502649 CD1D antigen precursor [Homo sapiens] 338 4e-93
gi|110618232 CD1E antigen isoform c precursor [Homo sapiens] 298 6e-81
gi|110618234 CD1E antigen isoform d precursor [Homo sapiens] 263 1e-70
gi|110618236 CD1E antigen isoform e precursor [Homo sapiens] 182 4e-46
gi|110618238 CD1E antigen isoform f precursor [Homo sapiens] 124 1e-28
gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H... 76 5e-14
gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom... 76 5e-14
gi|4504417 major histocompatibility complex, class I-related [Ho... 75 8e-14
gi|52630342 major histocompatibility complex, class I, C precurs... 73 4e-13
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 73 4e-13
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 72 5e-13
gi|62912479 major histocompatibility complex, class I, E precurs... 66 4e-11
gi|149158702 major histocompatibility complex, class I, F isofor... 65 6e-11
gi|149158698 major histocompatibility complex, class I, F isofor... 65 6e-11
gi|4504415 major histocompatibility complex, class I, G precurso... 65 1e-10
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 65 1e-10
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 65 1e-10
gi|24797067 major histocompatibility complex, class I, A precurs... 63 3e-10
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 61 1e-09
gi|24797076 major histocompatibility complex, class II, DP beta ... 61 2e-09
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 60 3e-09
gi|239740920 PREDICTED: similar to major histocompatibility comp... 57 2e-08
gi|239740918 PREDICTED: similar to major histocompatibility comp... 57 2e-08
gi|17986001 major histocompatibility complex, class I, B precurs... 57 2e-08
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 57 3e-08
>gi|4502645 CD1B antigen precursor [Homo sapiens]
Length = 333
Score = 688 bits (1776), Expect = 0.0
Identities = 333/333 (100%), Positives = 333/333 (100%)
Query: 1 MLLLPFQLLAVLFPGGNSEHAFQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDS 60
MLLLPFQLLAVLFPGGNSEHAFQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDS
Sbjct: 1 MLLLPFQLLAVLFPGGNSEHAFQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDS 60
Query: 61 DSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGC 120
DSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGC
Sbjct: 61 DSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGC 120
Query: 121 ELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILL 180
ELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILL
Sbjct: 121 ELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILL 180
Query: 181 YETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMR 240
YETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMR
Sbjct: 181 YETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMR 240
Query: 241 GEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRNPTS 300
GEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRNPTS
Sbjct: 241 GEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRNPTS 300
Query: 301 IGSIVLAIIVPSLLLLLCLALWYMRRRSYQNIP 333
IGSIVLAIIVPSLLLLLCLALWYMRRRSYQNIP
Sbjct: 301 IGSIVLAIIVPSLLLLLCLALWYMRRRSYQNIP 333
>gi|110618227 CD1C antigen precursor [Homo sapiens]
Length = 333
Score = 402 bits (1032), Expect = e-112
Identities = 201/333 (60%), Positives = 245/333 (73%), Gaps = 2/333 (0%)
Query: 1 MLLLPFQLLAVLFPGGNSEHAFQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDS 60
ML L F LLA+L PGG++ A Q SFHVIQ SF N +WA+ QGSGWLD+LQ HGWDS
Sbjct: 1 MLFLQFLLLALLLPGGDNADASQEHVSFHVIQIFSFVNQSWARGQGSGWLDELQTHGWDS 60
Query: 61 DSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGC 120
+SGT IFL WSKGNFS++E+++LE +FR Y+FG RE+QD A KYPFE+Q AGC
Sbjct: 61 ESGTIIFLHNWSKGNFSNEELSDLELLFRFYLFGLTREIQDHASQDYSKYPFEVQVKAGC 120
Query: 121 ELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALII-QYQGIMETVRIL 179
ELHSG + F + A GLD LS +N + VPSP GS AQ C L+ QY+G+ ETV L
Sbjct: 121 ELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVCHLLNHQYEGVTETVYNL 180
Query: 180 LYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWM 239
+ TCPR+LLG+L+AGK + RQV+PEAWLSS PS G G+L LVCH SGFYPKPVWV WM
Sbjct: 181 IRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFYPKPVWVTWM 240
Query: 240 RGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRNPT 299
R EQEQ GT+ GDILPNA+ TWYL+ L+VA E AGLSCRV+HSSL GQDIILYW +
Sbjct: 241 RNEQEQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGGQDIILYWGHHF 300
Query: 300 SIGSIVLAIIVPSLLLLLCLALWYMRRRSYQNI 332
S+ I L +IVP L++L+ L LW+ + SYQ+I
Sbjct: 301 SMNWIALVVIVP-LVILIVLVLWFKKHCSYQDI 332
>gi|110618224 CD1A antigen precursor [Homo sapiens]
Length = 327
Score = 394 bits (1012), Expect = e-110
Identities = 198/326 (60%), Positives = 240/326 (73%), Gaps = 2/326 (0%)
Query: 1 MLLLPFQLLAVLFPGGNSEHAFQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDS 60
ML L LLAVL PG + + P SFHV +SF N +W Q SGWL DLQ H WDS
Sbjct: 1 MLFLLLPLLAVL-PGDGNADGLKEPLSFHVTWIASFYNHSWKQNLVSGWLSDLQTHTWDS 59
Query: 61 DSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGC 120
+S T +FL PWS+GNFS++E ELE +FR+ ++ +A + Q +YPFEIQ GC
Sbjct: 60 NSSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGC 119
Query: 121 ELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILL 180
ELHSG SFL+ A G DF+S +N S +P P G+ A+ FC ++ Q Q + LL
Sbjct: 120 ELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLL 179
Query: 181 YETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMR 240
+TCPR++LG+L+AGKA LQRQVKPEAWLS GPSPGPG LQLVCHVSGFYPKPVWVMWMR
Sbjct: 180 SDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMR 239
Query: 241 GEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRNPTS 300
GEQEQQGTQ GDILP+A+ TWYLRATL+VA GEAA LSCRVKHSSLEGQDI+LYW + +S
Sbjct: 240 GEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHSS 299
Query: 301 IGSIVLAIIVPSLLLLLCLALWYMRR 326
+G I+LA+IVP LLLL+ LALW+ +R
Sbjct: 300 VGFIILAVIVP-LLLLIGLALWFRKR 324
>gi|110618240 CD1E antigen isoform a precursor [Homo sapiens]
Length = 388
Score = 358 bits (919), Expect = 4e-99
Identities = 183/341 (53%), Positives = 236/341 (69%), Gaps = 12/341 (3%)
Query: 1 MLLLPFQLLAVLFPGGN--------SEH-AFQGPTSFHVIQTSSFTNSTWAQTQGSGWLD 51
MLLL + PG N S H A + SF ++QTSSF N +WA ++GSGWL
Sbjct: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
Query: 52 DLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYP 111
DLQ HGWD+ GT FLKPWS GNFS +E+ L+ +F++Y F + VQ AG FQ++YP
Sbjct: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120
Query: 112 FEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQG 171
FEIQ +AGC ++ A FL A G DFLS + S PSP G RAQ C ++ +Y
Sbjct: 121 FEIQILAGCRMN---APQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLD 177
Query: 172 IMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYP 231
I E ++ LL TCPR+L G++ AG+++L+R+VKPEAWLS GPSPGPGRLQLVCHVSGFYP
Sbjct: 178 IKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYP 237
Query: 232 KPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDI 291
KPVWVMWMRGEQEQ+GTQ GD+LPNA+ TWYLRATLDVA GEAAGLSCRVKHSSL G D+
Sbjct: 238 KPVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDL 297
Query: 292 ILYWRNPTSIGSIVLAIIVPSLLLLLCLALWYMRRRSYQNI 332
I++W + ++ ++ +L++L+ + ++ S +NI
Sbjct: 298 IIHWGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNI 338
>gi|110618230 CD1E antigen isoform b precursor [Homo sapiens]
Length = 376
Score = 356 bits (913), Expect = 2e-98
Identities = 180/326 (55%), Positives = 229/326 (70%), Gaps = 12/326 (3%)
Query: 1 MLLLPFQLLAVLFPGGN--------SEH-AFQGPTSFHVIQTSSFTNSTWAQTQGSGWLD 51
MLLL + PG N S H A + SF ++QTSSF N +WA ++GSGWL
Sbjct: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
Query: 52 DLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYP 111
DLQ HGWD+ GT FLKPWS GNFS +E+ L+ +F++Y F + VQ AG FQ++YP
Sbjct: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120
Query: 112 FEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQG 171
FEIQ +AGC ++ A FL A G DFLS + S PSP G RAQ C ++ +Y
Sbjct: 121 FEIQILAGCRMN---APQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLD 177
Query: 172 IMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYP 231
I E ++ LL TCPR+L G++ AG+++L+R+VKPEAWLS GPSPGPGRLQLVCHVSGFYP
Sbjct: 178 IKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYP 237
Query: 232 KPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDI 291
KPVWVMWMRGEQEQ+GTQ GD+LPNA+ TWYLRATLDVA GEAAGLSCRVKHSSL G D+
Sbjct: 238 KPVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDL 297
Query: 292 ILYWRNPTSIGSIVLAIIVPSLLLLL 317
I++W + ++ ++ +L++L+
Sbjct: 298 IIHWGGYSIFLILICLTVIVTLVILV 323
>gi|4502649 CD1D antigen precursor [Homo sapiens]
Length = 335
Score = 338 bits (867), Expect = 4e-93
Identities = 176/331 (53%), Positives = 218/331 (65%), Gaps = 2/331 (0%)
Query: 4 LPFQLLAVLFPGGNSEHAFQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSG 63
L F LL L S Q +Q SSF NS+W +T G WL +LQ H W +DS
Sbjct: 4 LLFLLLWALLQAWGSAEVPQRLFPLRCLQISSFANSSWTRTDGLAWLGELQTHSWSNDSD 63
Query: 64 TAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGCELH 123
T LKPWS+G FSD++ L+ IFRVY F R+V++FA ++ YP E+Q AGCE+H
Sbjct: 64 TVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLELQVSAGCEVH 123
Query: 124 SGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILLYET 183
G A +F A G D LS + S P+ E ++ Q + ETV+ LL T
Sbjct: 124 PGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKWTRETVQWLLNGT 183
Query: 184 CPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQ 243
CP+++ G+L +GK++L++QVKP+AWLS GPSPGPGRL LVCHVSGFYPKPVWV WMRGEQ
Sbjct: 184 CPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWVKWMRGEQ 243
Query: 244 EQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRNP-TSIG 302
EQQGTQ GDILPNA+ TWYLRATLDV GEAAGLSCRVKHSSLEGQDI+LYW TS+G
Sbjct: 244 EQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVLYWGGSYTSMG 303
Query: 303 SIVLAIIVPSLLLLLC-LALWYMRRRSYQNI 332
I LA++ L LL+ + R+ SYQ +
Sbjct: 304 LIALAVLACLLFLLIVGFTSRFKRQTSYQGV 334
>gi|110618232 CD1E antigen isoform c precursor [Homo sapiens]
Length = 290
Score = 298 bits (762), Expect = 6e-81
Identities = 150/272 (55%), Positives = 189/272 (69%), Gaps = 12/272 (4%)
Query: 1 MLLLPFQLLAVLFPGGN--------SEH-AFQGPTSFHVIQTSSFTNSTWAQTQGSGWLD 51
MLLL + PG N S H A + SF ++QTSSF N +WA ++GSGWL
Sbjct: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
Query: 52 DLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYP 111
DLQ HGWD+ GT FLKPWS GNFS +E+ L+ +F++Y F + VQ AG FQ++YP
Sbjct: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120
Query: 112 FEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQG 171
FEIQ +AGC ++ A FL A G DFLS + S PSP G RAQ C ++ +Y
Sbjct: 121 FEIQILAGCRMN---APQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLD 177
Query: 172 IMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYP 231
I E ++ LL TCPR+L G++ AG+++L+R+VKPEAWLS GPSPGPGRLQLVCHVSGFYP
Sbjct: 178 IKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYP 237
Query: 232 KPVWVMWMRGEQEQQGTQLGDILPNANWTWYL 263
KPVWVMWMRGEQEQ+GTQ GD+LPNA+ TW++
Sbjct: 238 KPVWVMWMRGEQEQRGTQRGDVLPNADETWWI 269
>gi|110618234 CD1E antigen isoform d precursor [Homo sapiens]
Length = 321
Score = 263 bits (673), Expect = 1e-70
Identities = 135/250 (54%), Positives = 169/250 (67%), Gaps = 12/250 (4%)
Query: 1 MLLLPFQLLAVLFPGGN--------SEH-AFQGPTSFHVIQTSSFTNSTWAQTQGSGWLD 51
MLLL + PG N S H A + SF ++QTSSF N +WA ++GSGWL
Sbjct: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
Query: 52 DLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYP 111
DLQ HGWD+ GT FLKPWS GNFS +E+ L+ +F++Y F + VQ AG FQ++YP
Sbjct: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120
Query: 112 FEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQG 171
FEIQ +AGC ++ A FL A G DFLS + S PSP G RAQ C ++ +Y
Sbjct: 121 FEIQILAGCRMN---APQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLD 177
Query: 172 IMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYP 231
I E ++ LL TCPR+L G++ AG+++L+R+VKPEAWLS GPSPGPGRLQLVCHVSGFYP
Sbjct: 178 IKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYP 237
Query: 232 KPVWVMWMRG 241
KPVWVMWMRG
Sbjct: 238 KPVWVMWMRG 247
>gi|110618236 CD1E antigen isoform e precursor [Homo sapiens]
Length = 187
Score = 182 bits (462), Expect = 4e-46
Identities = 83/115 (72%), Positives = 98/115 (85%)
Query: 203 VKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWY 262
VKPEAWLS GPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQ+GTQ GD+LPNA+ TWY
Sbjct: 20 VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY 79
Query: 263 LRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRNPTSIGSIVLAIIVPSLLLLL 317
LRATLDVA GEAAGLSCRVKHSSL G D+I++W + ++ ++ +L++L+
Sbjct: 80 LRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILV 134
>gi|110618238 CD1E antigen isoform f precursor [Homo sapiens]
Length = 101
Score = 124 bits (311), Expect = 1e-28
Identities = 53/61 (86%), Positives = 58/61 (95%)
Query: 203 VKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWY 262
VKPEAWLS GPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQ+GTQ GD+LPNA+ TW+
Sbjct: 20 VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWW 79
Query: 263 L 263
+
Sbjct: 80 I 80
>gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 75.9 bits (185), Expect = 5e-14
Identities = 90/336 (26%), Positives = 147/336 (43%), Gaps = 37/336 (11%)
Query: 8 LLAVLFPG--GNSEHAFQGPTSFHVIQTSSFTNST---WAQTQGSGWLDDLQIHGWDSDS 62
LL L PG G H +H+ SS T W SGWL Q ++S
Sbjct: 13 LLLFLLPGSLGAESHL---SLLYHLTAVSSPAPGTPAFWV----SGWLGPQQYLSYNSLR 65
Query: 63 GTAIFLKPWSKGN----FSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIA 118
G A W N + +KE +L ++++ F + G K P+ +QG+
Sbjct: 66 GEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAF----KALGG----KGPYTLQGLL 117
Query: 119 GCELHSGGAIVSFLRGALGGLDFLS--VKNASCVPS-PEGGSRAQKFCALIIQYQGIMET 175
GCEL V + AL G +F++ +K + PE + +Q++ Q + +
Sbjct: 118 GCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQ---QDKAANKE 174
Query: 176 VRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVW 235
+ LL+ +CP L L G+ +L+ + P L + PS PG L C FYP +
Sbjct: 175 LTFLLF-SCPHRLREHLERGRGNLEWKEPPSMRLKARPS-SPGFSVLTCSAFSFYPPELQ 232
Query: 236 VMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYW 295
+ ++R GT GD PN++ +++ ++L V G+ C V+H+ L Q + +
Sbjct: 233 LRFLRNGL-AAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGL-AQPLRVEL 290
Query: 296 RNPTSIGSIVLAIIVPSLLLLLCL---ALWYMRRRS 328
+P +V+ I++ LLL AL + R RS
Sbjct: 291 ESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRS 326
>gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 75.9 bits (185), Expect = 5e-14
Identities = 90/336 (26%), Positives = 147/336 (43%), Gaps = 37/336 (11%)
Query: 8 LLAVLFPG--GNSEHAFQGPTSFHVIQTSSFTNST---WAQTQGSGWLDDLQIHGWDSDS 62
LL L PG G H +H+ SS T W SGWL Q ++S
Sbjct: 13 LLLFLLPGSLGAESHL---SLLYHLTAVSSPAPGTPAFWV----SGWLGPQQYLSYNSLR 65
Query: 63 GTAIFLKPWSKGN----FSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIA 118
G A W N + +KE +L ++++ F + G K P+ +QG+
Sbjct: 66 GEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAF----KALGG----KGPYTLQGLL 117
Query: 119 GCELHSGGAIVSFLRGALGGLDFLS--VKNASCVPS-PEGGSRAQKFCALIIQYQGIMET 175
GCEL V + AL G +F++ +K + PE + +Q++ Q + +
Sbjct: 118 GCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQ---QDKAANKE 174
Query: 176 VRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVW 235
+ LL+ +CP L L G+ +L+ + P L + PS PG L C FYP +
Sbjct: 175 LTFLLF-SCPHRLREHLERGRGNLEWKEPPSMRLKARPS-SPGFSVLTCSAFSFYPPELQ 232
Query: 236 VMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYW 295
+ ++R GT GD PN++ +++ ++L V G+ C V+H+ L Q + +
Sbjct: 233 LRFLRNGL-AAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGL-AQPLRVEL 290
Query: 296 RNPTSIGSIVLAIIVPSLLLLLCL---ALWYMRRRS 328
+P +V+ I++ LLL AL + R RS
Sbjct: 291 ESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRS 326
>gi|4504417 major histocompatibility complex, class I-related [Homo
sapiens]
Length = 341
Score = 75.1 bits (183), Expect = 8e-14
Identities = 74/290 (25%), Positives = 126/290 (43%), Gaps = 12/290 (4%)
Query: 48 GWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQ 107
G++D I +DS + PW N + ++ R + F E++ +
Sbjct: 48 GYVDSHPITTYDSVTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYN 107
Query: 108 MKYPFEIQGIAGCELHSGGAIVSFLRGALGGLDFLSV-KNASCVPSPEGGSRAQKFCALI 166
Q + GCEL G+ FL+ A G DFL K+ + + + K
Sbjct: 108 HSGSHTYQRMIGCELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEA 167
Query: 167 IQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHV 226
Q++ + + + L E C +L L GK LQR P ++ + PG L C
Sbjct: 168 NQHELLYQ--KNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKET-FPGVTALFCKA 224
Query: 227 SGFYPKPVWVMWMR-GEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSS 285
GFYP +++ WM+ GE+ Q GDILP+ + T+ A++++ + SC V+H
Sbjct: 225 HGFYPPEIYMTWMKNGEEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHC- 283
Query: 286 LEGQDIILYWRNPTSIGSIVLAIIVPSLLLLLCLA----LWYMRRRSYQN 331
G ++L + +V+ + S++L++ LA L + RR QN
Sbjct: 284 --GVHMVLQVPQESETIPLVMKAVSGSIVLVIVLAGVGVLVWRRRPREQN 331
>gi|52630342 major histocompatibility complex, class I, C precursor
[Homo sapiens]
Length = 366
Score = 72.8 bits (177), Expect = 4e-13
Identities = 69/287 (24%), Positives = 128/287 (44%), Gaps = 26/287 (9%)
Query: 48 GWLDDLQIHGWDSDSGT------AIFLKP-----WSKGNFSDKEVAELEEIFRVYIFGFA 96
G++DD Q +DSD+ + A +++ W + K A+ + + + G+
Sbjct: 50 GYVDDTQFVRFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQADRVSLRNLRGYY 109
Query: 97 REVQDFAGDFQMKYPFEIQGIAGCELHSGGAIV-SFLRGALGGLDFLSVKNASCVPSPEG 155
+ +D + +Q ++GC+L G ++ + + A G D++++ + S
Sbjct: 110 NQSEDGS--------HTLQRMSGCDLGPDGRLLRGYDQSAYDGKDYIALNED--LRSWTA 159
Query: 156 GSRAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSP 215
A + ++ E +R L TC +L L GK LQR P+ ++ P
Sbjct: 160 ADTAAQITQRKLEAARAAEQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPL- 218
Query: 216 GPGRLQLVCHVSGFYPKPVWVMWMR-GEQEQQGTQLGDILPNANWTWYLRATLDVADGEA 274
L C GFYP + + W R GE + Q T+L + P + T+ A + V G+
Sbjct: 219 SDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQE 278
Query: 275 AGLSCRVKHSSLEGQDIILYWRNPTSIGSIVLAIIVPSLLLLLCLAL 321
+C ++H L+ + + L W P+S +I + IV L +L+ LA+
Sbjct: 279 QRYTCHMQHEGLQ-EPLTLSW-EPSSQPTIPIMGIVAGLAVLVVLAV 323
>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
sapiens]
Length = 366
Score = 72.8 bits (177), Expect = 4e-13
Identities = 76/296 (25%), Positives = 129/296 (43%), Gaps = 30/296 (10%)
Query: 48 GWLDDLQIHGWDSDSGTAIF--LKPWSKGN---FSDKE---VAELEEIFRV---YIFGFA 96
G++DD Q +DSDS PW + + D++ V + + FRV + G+
Sbjct: 63 GYVDDTQFVRFDSDSANPREEPRAPWMEQEGPEYWDEQTRIVKDTAQSFRVGLNTLRGYY 122
Query: 97 REVQDFAGDFQMKYPFEIQGIAGCELHSGGAIV-SFLRGALGGLDFLSVKNASCVPSPEG 155
+ + + Q+ Y GC++ G + F++ A G D++++ + S
Sbjct: 123 NQSEAGSHTLQLMY--------GCDVGPDGRFLRGFMQDAYDGRDYIALNED--LRSWTA 172
Query: 156 GSRAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSP 215
A + + G E R L C L L GK L R P+A ++ P
Sbjct: 173 ADTAAQITKRKREAAGAAERQRNYLEGRCVEGLRRYLETGKDALLRADPPKAHVTHHPI- 231
Query: 216 GPGRLQLVCHVSGFYPKPVWVMWMR-GEQEQQGTQLGDILPNANWTWYLRATLDVADGEA 274
+ L C GFYP+ + + W R GE + Q +L + P+ + T+ A L V GE
Sbjct: 232 SEREVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDGTFQKWAALVVPSGEE 291
Query: 275 AGLSCRVKHSSLEGQDIILYWRNPTSIGSIVLAIIVPSLLLLLCL----ALWYMRR 326
+CRV+H L+ + + L W P +++ IIV +LL++ L +W +R
Sbjct: 292 QRYTCRVQHEGLQ-EPLTLRW-EPPQTSFLIMGIIVGLVLLVVALVAGAVIWRKKR 345
>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
Length = 298
Score = 72.4 bits (176), Expect = 5e-13
Identities = 67/256 (26%), Positives = 112/256 (43%), Gaps = 13/256 (5%)
Query: 45 QGSGWLDDLQIHGWDSDSGTAIFLKPWSK--GNFSDKEVAELEEIFRVYIFGFAREVQDF 102
Q G L+DLQ ++S + + W + G K+ ++L++ +++ ++
Sbjct: 48 QALGSLNDLQFFRYNSKDRKSQPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEY 107
Query: 103 AGDFQMKYPFEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNA--SCVP-SPEGGSRA 159
D + +QG GCE+ + + +F + G D++ + VP P
Sbjct: 108 YNDSNGSHV--LQGRFGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITK 165
Query: 160 QKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGR 219
QK+ A + Q + L E CP L L K L RQ P ++S +PG +
Sbjct: 166 QKWEAEPVYVQ----RAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKK 221
Query: 220 LQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSC 279
+L C FYP + V W R + Q+ GD+L N N T+ + V + A SC
Sbjct: 222 -KLKCLAYDFYPGKIDVHWTRAGEVQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSC 280
Query: 280 RVKHSSLEGQDIILYW 295
V+HSSL Q +++ W
Sbjct: 281 HVQHSSL-AQPLVVPW 295
>gi|62912479 major histocompatibility complex, class I, E precursor
[Homo sapiens]
Length = 358
Score = 66.2 bits (160), Expect = 4e-11
Identities = 74/286 (25%), Positives = 125/286 (43%), Gaps = 34/286 (11%)
Query: 48 GWLDDLQIHGWDSDSGTAIFLK--PWSKGNFSD------KEVAELEEIFRVYIFGFAREV 99
G++DD Q +D+D+ + + PW + S+ + + +IFRV + R +
Sbjct: 47 GYVDDTQFVRFDNDAASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNL----RTL 102
Query: 100 QDFAGDFQMKYPFEIQGIAGCELHSGGAIVSFLRG----ALGGLDFLSV----KNASCVP 151
+ + + +Q + GCEL G FLRG A G D+L++ ++ + V
Sbjct: 103 RGYYNQSEAG-SHTLQWMHGCELGPDGR---FLRGYEQFAYDGKDYLTLNEDLRSWTAVD 158
Query: 152 SPEGGSRAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSS 211
+ S + A ++Q R L +TC +L L GK L P+ ++
Sbjct: 159 TAAQISEQKSNDASEAEHQ------RAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTH 212
Query: 212 GPSPGPGRLQLVCHVSGFYPKPVWVMWMR-GEQEQQGTQLGDILPNANWTWYLRATLDVA 270
P L C GFYP + + W + GE Q T+L + P + T+ A + V
Sbjct: 213 HPI-SDHEATLRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVP 271
Query: 271 DGEAAGLSCRVKHSSLEGQDIILYWRNPTSIGSIVLAIIVPSLLLL 316
GE +C V+H L + + L W+ P S +I + I+ L+LL
Sbjct: 272 SGEEQRYTCHVQHEGLP-EPVTLRWK-PASQPTIPIVGIIAGLVLL 315
>gi|149158702 major histocompatibility complex, class I, F isoform 1
precursor [Homo sapiens]
Length = 442
Score = 65.5 bits (158), Expect = 6e-11
Identities = 57/203 (28%), Positives = 89/203 (43%), Gaps = 10/203 (4%)
Query: 114 IQGIAGCELHSGGAIV-SFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGI 172
+QG+ GC++ G ++ + + A G D++S+ + S + + +
Sbjct: 116 LQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNED--LRSWTAADTVAQITQRFYEAEEY 173
Query: 173 METVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPK 232
E R L C L L GK LQR P+A ++ P L C GFYP
Sbjct: 174 AEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPI-SDHEATLRCWALGFYPA 232
Query: 233 PVWVMWMR-GEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDI 291
+ + W R GE++ Q T+L + P + T+ A + V GE +C V+H L Q +
Sbjct: 233 EITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLP-QPL 291
Query: 292 ILYWR---NPT-SIGSIVLAIIV 310
IL W PT I IV ++V
Sbjct: 292 ILRWEQSPQPTIPIVGIVAGLVV 314
>gi|149158698 major histocompatibility complex, class I, F isoform 2
precursor [Homo sapiens]
Length = 346
Score = 65.5 bits (158), Expect = 6e-11
Identities = 57/203 (28%), Positives = 89/203 (43%), Gaps = 10/203 (4%)
Query: 114 IQGIAGCELHSGGAIV-SFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGI 172
+QG+ GC++ G ++ + + A G D++S+ + S + + +
Sbjct: 116 LQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNED--LRSWTAADTVAQITQRFYEAEEY 173
Query: 173 METVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPK 232
E R L C L L GK LQR P+A ++ P L C GFYP
Sbjct: 174 AEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPI-SDHEATLRCWALGFYPA 232
Query: 233 PVWVMWMR-GEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDI 291
+ + W R GE++ Q T+L + P + T+ A + V GE +C V+H L Q +
Sbjct: 233 EITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLP-QPL 291
Query: 292 ILYWR---NPT-SIGSIVLAIIV 310
IL W PT I IV ++V
Sbjct: 292 ILRWEQSPQPTIPIVGIVAGLVV 314
>gi|4504415 major histocompatibility complex, class I, G precursor
[Homo sapiens]
Length = 338
Score = 64.7 bits (156), Expect = 1e-10
Identities = 69/283 (24%), Positives = 122/283 (43%), Gaps = 28/283 (9%)
Query: 48 GWLDDLQIHGWDSDSGTAIFLKP------------WSKGNFSDKEVAELEEIFRVYIFGF 95
G++DD Q +DSDS ++P W + + K A+ + + + G+
Sbjct: 50 GYVDDTQFVRFDSDSACPR-MEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGY 108
Query: 96 AREVQDFAGDFQMKYPFEIQGIAGCELHSGGAIV-SFLRGALGGLDFLSVKNASCVPSPE 154
+ + + +Q + GC+L S G ++ + + A G D+L++ + S
Sbjct: 109 YNQSEASS--------HTLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNED--LRSWT 158
Query: 155 GGSRAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPS 214
A + + + E R L TC +L L GK LQR P+ ++ P
Sbjct: 159 AADTAAQISKRKCEAANVAEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPV 218
Query: 215 PGPGRLQLVCHVSGFYPKPVWVMWMR-GEQEQQGTQLGDILPNANWTWYLRATLDVADGE 273
L C GFYP + + W R GE + Q +L + P + T+ A + V GE
Sbjct: 219 -FDYEATLRCWALGFYPAEIILTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGE 277
Query: 274 AAGLSCRVKHSSLEGQDIILYWRNPTSIGSIVLAIIVPSLLLL 316
+C V+H L + ++L W+ +S+ +I + IV L++L
Sbjct: 278 EQRYTCHVQHEGLP-EPLMLRWKQ-SSLPTIPIMGIVAGLVVL 318
>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
sapiens]
Length = 325
Score = 64.7 bits (156), Expect = 1e-10
Identities = 61/291 (20%), Positives = 122/291 (41%), Gaps = 16/291 (5%)
Query: 48 GWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQ 107
G++DD +D +S PW S + +L + + + F + +
Sbjct: 28 GYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHN 87
Query: 108 -MKYPFEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALI 166
K +Q I GCE+ + + + G D L C + + + +
Sbjct: 88 HSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF----CPDTLDWRAAEPRAWPTK 143
Query: 167 IQYQGIMETVR---ILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLV 223
++++ R L CP L +L G+ L +QV P ++ + L+
Sbjct: 144 LEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLR-- 201
Query: 224 CHVSGFYPKPVWVMWMRGEQEQQGTQLG--DILPNANWTWYLRATLDVADGEAAGLSCRV 281
C +YP+ + + W++ +Q + D+LPN + T+ TL V GE +C+V
Sbjct: 202 CRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQV 261
Query: 282 KHSSLEGQDIILYWRNPTSIGSIVLAII--VPSLLLLLCLALWYMRRRSYQ 330
+H L+ Q +I+ W P+ G++V+ +I + +++L + + ++ R Q
Sbjct: 262 EHPGLD-QPLIVIW-EPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 310
>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
sapiens]
Length = 348
Score = 64.7 bits (156), Expect = 1e-10
Identities = 61/291 (20%), Positives = 122/291 (41%), Gaps = 16/291 (5%)
Query: 48 GWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQ 107
G++DD +D +S PW S + +L + + + F + +
Sbjct: 51 GYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHN 110
Query: 108 -MKYPFEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALI 166
K +Q I GCE+ + + + G D L C + + + +
Sbjct: 111 HSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF----CPDTLDWRAAEPRAWPTK 166
Query: 167 IQYQGIMETVR---ILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLV 223
++++ R L CP L +L G+ L +QV P ++ + L+
Sbjct: 167 LEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLR-- 224
Query: 224 CHVSGFYPKPVWVMWMRGEQEQQGTQLG--DILPNANWTWYLRATLDVADGEAAGLSCRV 281
C +YP+ + + W++ +Q + D+LPN + T+ TL V GE +C+V
Sbjct: 225 CRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQV 284
Query: 282 KHSSLEGQDIILYWRNPTSIGSIVLAII--VPSLLLLLCLALWYMRRRSYQ 330
+H L+ Q +I+ W P+ G++V+ +I + +++L + + ++ R Q
Sbjct: 285 EHPGLD-QPLIVIW-EPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 333
>gi|24797067 major histocompatibility complex, class I, A precursor
[Homo sapiens]
Length = 365
Score = 63.2 bits (152), Expect = 3e-10
Identities = 71/286 (24%), Positives = 121/286 (42%), Gaps = 34/286 (11%)
Query: 48 GWLDDLQIHGWDSDSGTAIFLKP------------WSKGNFSDKEVAELEEIFRVYIFGF 95
G++DD Q +DSD+ + ++P W + + K ++ + + + G+
Sbjct: 50 GYVDDTQFVRFDSDAASQR-MEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGY 108
Query: 96 AREVQDFAGDFQMKYPFEIQGIAGCELHSGGAIVSFLRG----ALGGLDFLSVKNASCVP 151
+ + + Q+ Y GC++ S G FLRG A G D++++ +
Sbjct: 109 YNQSEAGSHTIQIMY--------GCDVGSDGR---FLRGYRQDAYDGKDYIALNED--LR 155
Query: 152 SPEGGSRAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSS 211
S A + + E +R L TC +L L GK LQR P+ ++
Sbjct: 156 SWTAADMAAQITKRKWEAAHEAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTH 215
Query: 212 GPSPGPGRLQLVCHVSGFYPKPVWVMWMR-GEQEQQGTQLGDILPNANWTWYLRATLDVA 270
P L C GFYP + + W R GE + Q T+L + P + T+ A + V
Sbjct: 216 HPI-SDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP 274
Query: 271 DGEAAGLSCRVKHSSLEGQDIILYWRNPTSIGSIVLAIIVPSLLLL 316
GE +C V+H L + + L W +S +I + I+ L+LL
Sbjct: 275 SGEEQRYTCHVQHEGLP-KPLTLRW-ELSSQPTIPIVGIIAGLVLL 318
>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
sapiens]
Length = 260
Score = 61.2 bits (147), Expect = 1e-09
Identities = 41/158 (25%), Positives = 78/158 (49%), Gaps = 8/158 (5%)
Query: 177 RILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWV 236
R L CP L +L G+ L +QV P ++ + L+ C +YP+ + +
Sbjct: 92 RAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLR--CRALNYYPQNITM 149
Query: 237 MWMRGEQEQQGTQLG--DILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILY 294
W++ +Q + D+LPN + T+ TL V GE +C+V+H L+ Q +I+
Sbjct: 150 KWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLD-QPLIVI 208
Query: 295 WRNPTSIGSIVLAII--VPSLLLLLCLALWYMRRRSYQ 330
W P+ G++V+ +I + +++L + + ++ R Q
Sbjct: 209 W-EPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 245
>gi|24797076 major histocompatibility complex, class II, DP beta 1
precursor [Homo sapiens]
Length = 258
Score = 60.8 bits (146), Expect = 2e-09
Identities = 42/145 (28%), Positives = 70/145 (48%), Gaps = 19/145 (13%)
Query: 195 GKADLQRQVKPEAWLS-SGPSPGPGRLQLVCHVSGFYPKPVWVMW-MRGEQEQQGTQLGD 252
G LQR+V+P +S S P LVCHV+ FYP + V W + G++E G +
Sbjct: 114 GPMTLQRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTN 173
Query: 253 ILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYW---------RNPTSIGS 303
++ N +WT+ + L++ + +C+V+H+SL+ + + W + T G
Sbjct: 174 LIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLD-SPVTVEWKAQSDSARSKTLTGAGG 232
Query: 304 IVLAIIVPSLLLLLCLALWYMRRRS 328
VL +I+ C +M RRS
Sbjct: 233 FVLGLII-------CGVGIFMHRRS 250
>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
sapiens]
Length = 334
Score = 60.1 bits (144), Expect = 3e-09
Identities = 60/291 (20%), Positives = 117/291 (40%), Gaps = 30/291 (10%)
Query: 48 GWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQ 107
G++DD +D +S PW S + +L + + + F + +
Sbjct: 51 GYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHN 110
Query: 108 -MKYPFEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALI 166
K +Q I GCE+ + + + G D L C + + + +
Sbjct: 111 HSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF----CPDTLDWRAAEPRAWPTK 166
Query: 167 IQYQGIMETVR---ILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLV 223
++++ R L CP L +L G+ L +QV L
Sbjct: 167 LEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVTT----------------LR 210
Query: 224 CHVSGFYPKPVWVMWMRGEQEQQGTQLG--DILPNANWTWYLRATLDVADGEAAGLSCRV 281
C +YP+ + + W++ +Q + D+LPN + T+ TL V GE +C+V
Sbjct: 211 CRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQV 270
Query: 282 KHSSLEGQDIILYWRNPTSIGSIVLAII--VPSLLLLLCLALWYMRRRSYQ 330
+H L+ Q +I+ W P+ G++V+ +I + +++L + + ++ R Q
Sbjct: 271 EHPGLD-QPLIVIW-EPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 319
>gi|239740920 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 2 [Homo sapiens]
Length = 261
Score = 57.4 bits (137), Expect = 2e-08
Identities = 39/133 (29%), Positives = 63/133 (47%), Gaps = 12/133 (9%)
Query: 196 KADLQRQVKPEAWLSSGPSPGPGRLQL-VCHVSGFYPKPVWVMWMRGEQEQ-QGTQLGDI 253
+ LQR+V+P +S + L VC V+ FYP + V W R +QE+ G +
Sbjct: 120 RTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPL 179
Query: 254 LPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRNP---------TSIGSI 304
+ N +WT+ + L++ +C V+H SL+ II+ WR + IG
Sbjct: 180 IRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQ-NPIIVEWRAQSESAQSKMLSGIGGF 238
Query: 305 VLAIIVPSLLLLL 317
VL +I L L++
Sbjct: 239 VLGLIFLGLGLII 251
>gi|239740918 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 1 [Homo sapiens]
Length = 281
Score = 57.4 bits (137), Expect = 2e-08
Identities = 39/133 (29%), Positives = 63/133 (47%), Gaps = 12/133 (9%)
Query: 196 KADLQRQVKPEAWLSSGPSPGPGRLQL-VCHVSGFYPKPVWVMWMRGEQEQ-QGTQLGDI 253
+ LQR+V+P +S + L VC V+ FYP + V W R +QE+ G +
Sbjct: 120 RTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPL 179
Query: 254 LPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRNP---------TSIGSI 304
+ N +WT+ + L++ +C V+H SL+ II+ WR + IG
Sbjct: 180 IRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQ-NPIIVEWRAQSESAQSKMLSGIGGF 238
Query: 305 VLAIIVPSLLLLL 317
VL +I L L++
Sbjct: 239 VLGLIFLGLGLII 251
>gi|17986001 major histocompatibility complex, class I, B precursor
[Homo sapiens]
Length = 362
Score = 57.0 bits (136), Expect = 2e-08
Identities = 66/285 (23%), Positives = 119/285 (41%), Gaps = 22/285 (7%)
Query: 48 GWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAEL----EEIFRVYIFGFAREVQDFA 103
G++DD Q +DSD+ + + + + ++E E +I++ +++
Sbjct: 50 GYVDDTQFVRFDSDAASP---REEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLR 106
Query: 104 GDFQMKYP--FEIQGIAGCELHSGGAIVSFLRG----ALGGLDFLSVKNASCVPSPEGGS 157
G + +Q + GC++ G + LRG A G D++++ + S
Sbjct: 107 GYYNQSEAGSHTLQSMYGCDVGPDGRL---LRGHDQYAYDGKDYIALNED--LRSWTAAD 161
Query: 158 RAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGP 217
A + + E R L C +L L GK L+R P+ ++ P
Sbjct: 162 TAAQITQRKWEAAREAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPI-SD 220
Query: 218 GRLQLVCHVSGFYPKPVWVMWMR-GEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAG 276
L C GFYP + + W R GE + Q T+L + P + T+ A + V GE
Sbjct: 221 HEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQR 280
Query: 277 LSCRVKHSSLEGQDIILYWRNPTSIGSIVLAIIVPSLLLLLCLAL 321
+C V+H L + + L W P+S ++ + IV L +L + +
Sbjct: 281 YTCHVQHEGLP-KPLTLRW-EPSSQSTVPIVGIVAGLAVLAVVVI 323
>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
sapiens]
Length = 246
Score = 56.6 bits (135), Expect = 3e-08
Identities = 40/158 (25%), Positives = 73/158 (46%), Gaps = 22/158 (13%)
Query: 177 RILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWV 236
R L CP L +L G+ L +QV L C +YP+ + +
Sbjct: 92 RAYLERDCPAQLQQLLELGRGVLDQQVTT----------------LRCRALNYYPQNITM 135
Query: 237 MWMRGEQEQQGTQLG--DILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILY 294
W++ +Q + D+LPN + T+ TL V GE +C+V+H L+ Q +I+
Sbjct: 136 KWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLD-QPLIVI 194
Query: 295 WRNPTSIGSIVLAII--VPSLLLLLCLALWYMRRRSYQ 330
W P+ G++V+ +I + +++L + + ++ R Q
Sbjct: 195 W-EPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 231
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.139 0.446
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,329,010
Number of Sequences: 37866
Number of extensions: 680471
Number of successful extensions: 1714
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 77
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 1542
Number of HSP's gapped (non-prelim): 140
length of query: 333
length of database: 18,247,518
effective HSP length: 103
effective length of query: 230
effective length of database: 14,347,320
effective search space: 3299883600
effective search space used: 3299883600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.