Guide to the Human Genome
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Name: HFE Sequence: fasta or formatted (76aa) NCBI GI: 21040357
Description:

hemochromatosis protein isoform 11 precursor

Referenced in:

HLA and Related Proteins
Iron, Copper, and Arsenic Metabolism

Other entries for this name:
alt prot [242aa] hemochromatosis protein isoform 3 precursor
alt prot [256aa] hemochromatosis protein isoform 4 precursor
alt prot [334aa] hemochromatosis protein isoform 6 precursor
alt prot [260aa] hemochromatosis protein isoform 7 precursor
alt prot [246aa] hemochromatosis protein isoform 8 precursor
alt prot [325aa] hemochromatosis protein isoform 9 precursor
alt prot [168aa] hemochromatosis protein isoform 10 precursor
alt prot [348aa] hemochromatosis protein isoform 1 precursor
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.9          6           1
 C cysteine            0.0          0           0
 D aspartate           0.0          0           0
 E glutamate           2.6          2           1
 F phenylalanine       3.9          3           1
 G glycine            11.8          9           1
 H histidine           1.3          1           1
 I isoleucine         10.5          8           2
 K lysine              1.3          1           1
 L leucine            18.4         14           4
 M methionine          3.9          3           1
 N asparagine          0.0          0           0
 P proline             5.3          4           1
 Q glutamine           5.3          4           1
 R arginine            9.2          7           1
 S serine              5.3          4           1
 T threonine           2.6          2           1
 V valine              9.2          7           2
 W tryptophan          0.0          0           0
 Y tyrosine            1.3          1           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hemochromatosis protein isoform 11 precursor 
HFE                   0.617   hemochromatosis protein isoform 10 precursor 
HFE                   0.617   hemochromatosis protein isoform 9 precursor 
HFE                   0.617   hemochromatosis protein isoform 8 precursor 
HFE                   0.617   hemochromatosis protein isoform 7 precursor 
HFE                   0.617   hemochromatosis protein isoform 6 precursor 
HFE                   0.617   hemochromatosis protein isoform 4 precursor 
HFE                   0.617   hemochromatosis protein isoform 3 precursor 
HFE                   0.617   hemochromatosis protein isoform 1 precursor 
KIRREL                0.067   kin of IRRE like 
HLA-B                 0.058   major histocompatibility complex, class I, B precurs...
HLA-C                 0.042   major histocompatibility complex, class I, C precurs...
MEGF10                0.042   multiple EGF-like-domains 10 
EPHA2                 0.042   ephrin receptor EphA2 
LILRB5                0.042   leukocyte immunoglobulin-like receptor, subfamily B...
LILRB5                0.042   leukocyte immunoglobulin-like receptor, subfamily B...
LILRB5                0.042   leukocyte immunoglobulin-like receptor, subfamily B, ...
SLC26A3               0.025   solute carrier family 26, member 3 
CR1                   0.025   complement receptor 1 isoform S precursor 
CR1                   0.025   complement receptor 1 isoform F precursor 
GDAP1                 0.025   ganglioside-induced differentiation-associated prot...
GDAP1                 0.025   ganglioside-induced differentiation-associated prot...
PDCD1                 0.025   programmed cell death 1 precursor 
SORCS2                0.025   VPS10 domain receptor protein SORCS 2 
SUSD2                 0.025   sushi domain containing 2 
LOC100292064          0.017   PREDICTED: hypothetical protein XP_002345331 
LOC100290378          0.017   PREDICTED: hypothetical protein XP_002347782 
LOC100287901          0.017   PREDICTED: hypothetical protein XP_002342210 
PTPRM                 0.017   protein tyrosine phosphatase, receptor type, M isof...
PTPRM                 0.017   protein tyrosine phosphatase, receptor type, M isof...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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