Search of human proteins with 4504403

Search of human proteins with 4504403

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504403 major histocompatibility complex, class II, DO beta
precursor [Homo sapiens]
         (273 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504403 major histocompatibility complex, class II, DO beta p...   558   e-159
gi|239758095 PREDICTED: similar to major histocompatibility comp...   303   1e-82
gi|239740749 PREDICTED: similar to major histocompatibility comp...   303   1e-82
gi|169168591 PREDICTED: similar to major histocompatibility comp...   302   2e-82
gi|239748788 PREDICTED: similar to major histocompatibility comp...   301   5e-82
gi|150418002 major histocompatibility complex, class II, DQ beta...   300   7e-82
gi|239740863 PREDICTED: similar to major histocompatibility comp...   300   9e-82
gi|239513955 PREDICTED: similar to major histocompatibility comp...   300   9e-82
gi|155030211 major histocompatibility complex, class II, DR beta...   297   8e-81
gi|239740920 PREDICTED: similar to major histocompatibility comp...   296   1e-80
gi|239740918 PREDICTED: similar to major histocompatibility comp...   296   1e-80
gi|239740745 PREDICTED: similar to HLA class II histocompatibili...   295   3e-80
gi|239740695 PREDICTED: similar to HLA class II histocompatibili...   295   3e-80
gi|239748785 PREDICTED: similar to HLA class II histocompatibili...   293   1e-79
gi|52630344 major histocompatibility complex, class II, DR beta ...   292   2e-79
gi|239748820 PREDICTED: hypothetical protein XP_002346811 [Homo ...   288   3e-78
gi|239740853 PREDICTED: similar to major histocompatibility comp...   287   6e-78
gi|239740743 PREDICTED: similar to HLA class II histocompatibili...   287   6e-78
gi|239740693 PREDICTED: similar to HLA class II histocompatibili...   287   6e-78
gi|18641375 major histocompatibility complex, class II, DR beta ...   287   6e-78
gi|17986005 major histocompatibility complex, class II, DR beta ...   285   4e-77
gi|239740857 PREDICTED: similar to major histocompatibility comp...   283   1e-76
gi|239758090 PREDICTED: major histocompatibility complex, class ...   282   2e-76
gi|239740855 PREDICTED: similar to major histocompatibility comp...   282   3e-76
gi|239740859 PREDICTED: similar to major histocompatibility comp...   276   1e-74
gi|24797076 major histocompatibility complex, class II, DP beta ...   273   9e-74
gi|239758092 PREDICTED: similar to HLA class II histocompatibili...   246   1e-65
gi|169217452 PREDICTED: similar to HLA class II histocompatibili...   240   1e-63
gi|169168671 PREDICTED: similar to MHC class II antigen [Homo sa...   170   1e-42
gi|169168589 PREDICTED: similar to MHC class II antigen [Homo sa...   115   3e-26

>gi|4504403 major histocompatibility complex, class II, DO beta
           precursor [Homo sapiens]
          Length = 273

 Score =  558 bits (1439), Expect = e-159
 Identities = 273/273 (100%), Positives = 273/273 (100%)

Query: 1   MGSGWVPWVVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNL 60
           MGSGWVPWVVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNL
Sbjct: 1   MGSGWVPWVVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNL 60

Query: 61  EEYVRFDSDVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRK 120
           EEYVRFDSDVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRK
Sbjct: 61  EEYVRFDSDVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRK 120

Query: 121 VQPEVTVYPERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWT 180
           VQPEVTVYPERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWT
Sbjct: 121 VQPEVTVYPERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWT 180

Query: 181 FQTVVMLEMTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLL 240
           FQTVVMLEMTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLL
Sbjct: 181 FQTVVMLEMTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLL 240

Query: 241 VGIVIQLRAQKGYVRTQMSGNEVSRAVLLPQSC 273
           VGIVIQLRAQKGYVRTQMSGNEVSRAVLLPQSC
Sbjct: 241 VGIVIQLRAQKGYVRTQMSGNEVSRAVLLPQSC 273


>gi|239758095 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 [Homo sapiens]
          Length = 281

 Score =  303 bits (775), Expect = 1e-82
 Identities = 150/237 (63%), Positives = 180/237 (75%)

Query: 16  LTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDSDVGMFVA 75
           L+ L + + +G DSPEDFV Q K  CYFTNGTE+V+ V R I+N EE VRFDSDVG F A
Sbjct: 22  LSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNREEIVRFDSDVGEFRA 81

Query: 76  LTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVYPERTPLL 135
           +T LG P AE WNS+ D+LER R AVD VCRHNY+L    T+ R+V+P VT+ P RT  L
Sbjct: 82  VTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRRVEPTVTISPSRTEAL 141

Query: 136 HQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLEMTPELGH 195
           + HNLL CSVT FYP  IK++WF NGQEE AGV+ST  IRNGDWTFQ +VMLEMTP+ G 
Sbjct: 142 NHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGD 201

Query: 196 VYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLRAQKG 252
           VYTC V+H SL SP++VEWRAQSE +  KMLSGI  F+LGLIFL +G++I  R+QKG
Sbjct: 202 VYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLGLGLIIHHRSQKG 258


>gi|239740749 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 [Homo sapiens]
          Length = 281

 Score =  303 bits (775), Expect = 1e-82
 Identities = 150/237 (63%), Positives = 180/237 (75%)

Query: 16  LTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDSDVGMFVA 75
           L+ L + + +G DSPEDFV Q K  CYFTNGTE+V+ V R I+N EE VRFDSDVG F A
Sbjct: 22  LSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNREEIVRFDSDVGEFRA 81

Query: 76  LTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVYPERTPLL 135
           +T LG P AE WNS+ D+LER R AVD VCRHNY+L    T+ R+V+P VT+ P RT  L
Sbjct: 82  VTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRRVEPTVTISPSRTEAL 141

Query: 136 HQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLEMTPELGH 195
           + HNLL CSVT FYP  IK++WF NGQEE AGV+ST  IRNGDWTFQ +VMLEMTP+ G 
Sbjct: 142 NHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGD 201

Query: 196 VYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLRAQKG 252
           VYTC V+H SL SP++VEWRAQSE +  KMLSGI  F+LGLIFL +G++I  R+QKG
Sbjct: 202 VYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLGLGLIIHHRSQKG 258


>gi|169168591 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 isoform 1 [Homo sapiens]
          Length = 261

 Score =  302 bits (774), Expect = 2e-82
 Identities = 147/244 (60%), Positives = 184/244 (75%)

Query: 9   VVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDS 68
           V  + + L  L + + +G DSPEDFV Q K  CYFTNGTE+V+ V R+I+N EEY RFDS
Sbjct: 15  VATVTLMLAMLSTPVAEGRDSPEDFVFQFKGMCYFTNGTERVRGVTRYIYNREEYARFDS 74

Query: 69  DVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVY 128
           DVG++ A+T LG P AE WNS+ ++LER+R +VD VCRHNY+L    T+ R+V+P VT+ 
Sbjct: 75  DVGVYRAVTPLGPPAAEYWNSQKEVLERTRASVDTVCRHNYQLELRTTLQRRVEPTVTIS 134

Query: 129 PERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLE 188
           P RT  L+ HNLL CSVT FYP  IK++WF N QEE AGV+ST  IRNGDWTFQ +VMLE
Sbjct: 135 PSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLE 194

Query: 189 MTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLR 248
           MTP+ G VYTC V+H SL SP++VEWRAQSE +  KMLSGI  F+LGLIFL +G++I  R
Sbjct: 195 MTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLGLGLIIHHR 254

Query: 249 AQKG 252
           +QKG
Sbjct: 255 SQKG 258


>gi|239748788 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 isoform 2 [Homo sapiens]
          Length = 281

 Score =  301 bits (770), Expect = 5e-82
 Identities = 150/244 (61%), Positives = 181/244 (74%)

Query: 9   VVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDS 68
           V  + + L  L + + +G DSPEDFV Q K  CYFTNGTE+V+ V R I+N EE VRFDS
Sbjct: 15  VATVTLMLAMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNREEIVRFDS 74

Query: 69  DVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVY 128
           DVG F A+T LG P AE WNS+ D+LER R AVD VCRHNY+L    T+ R+V+P VT+ 
Sbjct: 75  DVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRRVEPTVTIS 134

Query: 129 PERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLE 188
           P RT  L+ HNLL CSVT FYP  IK++WF N QEE AGV+ST  IRNGDWTFQ +VMLE
Sbjct: 135 PSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLE 194

Query: 189 MTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLR 248
           MTP+ G VYTC V+H SL SP++VEWRAQSE +  KMLSGI  F+LGLIFL +G++I  R
Sbjct: 195 MTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLGLGLIIHHR 254

Query: 249 AQKG 252
           +QKG
Sbjct: 255 SQKG 258


>gi|150418002 major histocompatibility complex, class II, DQ beta 1
           precursor [Homo sapiens]
          Length = 261

 Score =  300 bits (769), Expect = 7e-82
 Identities = 144/244 (59%), Positives = 183/244 (75%)

Query: 9   VVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDS 68
           V  + + L  L S + +G DSPEDFV Q K  CYFTNGTE+V+ V R+I+N EEY RFDS
Sbjct: 15  VATVTLMLAMLSSLLAEGRDSPEDFVFQFKGMCYFTNGTERVRLVTRYIYNREEYARFDS 74

Query: 69  DVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVY 128
           DVG++ A+T  G+PDAE WNS+ ++LE +R  +D VCRHNY +     + R+V+P VT+ 
Sbjct: 75  DVGVYRAVTPQGRPDAEYWNSQKEVLEGTRAELDTVCRHNYEVAFRGILQRRVEPTVTIS 134

Query: 129 PERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLE 188
           P RT  L+ HNLL CSVT FYPG IK++WF N QEE AGV+ST  IRNGDWTFQ +VMLE
Sbjct: 135 PSRTEALNHHNLLVCSVTDFYPGQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLE 194

Query: 189 MTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLR 248
           MTP+ G VYTC V+H SL SP++VEWRAQSE +  KMLSG+  F+LGLIFL +G++I+ R
Sbjct: 195 MTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGVGGFVLGLIFLGLGLIIRQR 254

Query: 249 AQKG 252
           +QKG
Sbjct: 255 SQKG 258


>gi|239740863 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 [Homo sapiens]
          Length = 281

 Score =  300 bits (768), Expect = 9e-82
 Identities = 149/237 (62%), Positives = 179/237 (75%)

Query: 16  LTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDSDVGMFVA 75
           L+ L + + +G DSPEDFV Q K  CYFTNGTE+V+ V R I+N EE VRFDSDVG F A
Sbjct: 22  LSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNREEIVRFDSDVGEFRA 81

Query: 76  LTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVYPERTPLL 135
           +T LG P AE WNS+ D+LER R AVD VCRHNY+L    T+ R+V+P VT+ P RT  L
Sbjct: 82  VTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRRVEPTVTISPSRTEAL 141

Query: 136 HQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLEMTPELGH 195
           + HNLL CSVT FYP  IK++WF N QEE AGV+ST  IRNGDWTFQ +VMLEMTP+ G 
Sbjct: 142 NHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGD 201

Query: 196 VYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLRAQKG 252
           VYTC V+H SL SP++VEWRAQSE +  KMLSGI  F+LGLIFL +G++I  R+QKG
Sbjct: 202 VYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLGLGLIIHHRSQKG 258


>gi|239513955 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 [Homo sapiens]
          Length = 281

 Score =  300 bits (768), Expect = 9e-82
 Identities = 149/237 (62%), Positives = 179/237 (75%)

Query: 16  LTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDSDVGMFVA 75
           L+ L + + +G DSPEDFV Q K  CYFTNGTE+V+ V R I+N EE VRFDSDVG F A
Sbjct: 22  LSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNREEIVRFDSDVGEFRA 81

Query: 76  LTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVYPERTPLL 135
           +T LG P AE WNS+ D+LER R AVD VCRHNY+L    T+ R+V+P VT+ P RT  L
Sbjct: 82  VTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRRVEPTVTISPSRTEAL 141

Query: 136 HQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLEMTPELGH 195
           + HNLL CSVT FYP  IK++WF N QEE AGV+ST  IRNGDWTFQ +VMLEMTP+ G 
Sbjct: 142 NHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGD 201

Query: 196 VYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLRAQKG 252
           VYTC V+H SL SP++VEWRAQSE +  KMLSGI  F+LGLIFL +G++I  R+QKG
Sbjct: 202 VYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLGLGLIIHHRSQKG 258


>gi|155030211 major histocompatibility complex, class II, DR beta 1
           precursor [Homo sapiens]
          Length = 266

 Score =  297 bits (760), Expect = 8e-81
 Identities = 144/252 (57%), Positives = 187/252 (74%)

Query: 9   VVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDS 68
           + AL V L  L S +    D+   F+ Q K +C+F NGTE+V+F+ R+ +N EE VRFDS
Sbjct: 12  MTALTVTLMVLSSPLALSGDTRPRFLWQPKRECHFFNGTERVRFLDRYFYNQEESVRFDS 71

Query: 69  DVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVY 128
           DVG F A+T+LG+PDAE WNS+ D+LE++R AVD  CRHNY +   FTV R+VQP+VTVY
Sbjct: 72  DVGEFRAVTELGRPDAEYWNSQKDILEQARAAVDTYCRHNYGVVESFTVQRRVQPKVTVY 131

Query: 129 PERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLE 188
           P +T  L  HNLL CSV+GFYPG I+++WFLNGQEE+AG++STG I+NGDWTFQT+VMLE
Sbjct: 132 PSKTQPLQHHNLLVCSVSGFYPGSIEVRWFLNGQEEKAGMVSTGLIQNGDWTFQTLVMLE 191

Query: 189 MTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLR 248
             P  G VYTC V+H S+ SP++VEWRA+SE +  KMLSG+  F+LGL+FL  G+ I  R
Sbjct: 192 TVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFR 251

Query: 249 AQKGYVRTQMSG 260
            QKG+   Q +G
Sbjct: 252 NQKGHSGLQPTG 263


>gi|239740920 PREDICTED: similar to major histocompatibility
           complex, class II, DQ beta 1 isoform 2 [Homo sapiens]
          Length = 261

 Score =  296 bits (758), Expect = 1e-80
 Identities = 144/244 (59%), Positives = 181/244 (74%)

Query: 9   VVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDS 68
           V  + + L  L + + +G DSPEDFV Q K  CYFTNGTE+V+ V R+I+N EEY RFDS
Sbjct: 15  VATVTLMLAMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRGVTRYIYNREEYARFDS 74

Query: 69  DVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVY 128
           DVG++ A+T LG P AE WNS+ ++LER+R  +D VCRHNY+L    T+ R+V+P VT+ 
Sbjct: 75  DVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRRVEPTVTIS 134

Query: 129 PERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLE 188
           P RT  L+ HNLL CSVT FYP  IK++WF N QEE  GV+ST  IRNGDWTFQ +VMLE
Sbjct: 135 PSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWTFQILVMLE 194

Query: 189 MTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLR 248
           MTP+ G VYTC V+H SL +P+ VEWRAQSE +  KMLSGI  F+LGLIFL +G++I  R
Sbjct: 195 MTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKMLSGIGGFVLGLIFLGLGLIIHHR 254

Query: 249 AQKG 252
           +QKG
Sbjct: 255 SQKG 258


>gi|239740918 PREDICTED: similar to major histocompatibility
           complex, class II, DQ beta 1 isoform 1 [Homo sapiens]
          Length = 281

 Score =  296 bits (758), Expect = 1e-80
 Identities = 144/244 (59%), Positives = 181/244 (74%)

Query: 9   VVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDS 68
           V  + + L  L + + +G DSPEDFV Q K  CYFTNGTE+V+ V R+I+N EEY RFDS
Sbjct: 15  VATVTLMLAMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRGVTRYIYNREEYARFDS 74

Query: 69  DVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVY 128
           DVG++ A+T LG P AE WNS+ ++LER+R  +D VCRHNY+L    T+ R+V+P VT+ 
Sbjct: 75  DVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRRVEPTVTIS 134

Query: 129 PERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLE 188
           P RT  L+ HNLL CSVT FYP  IK++WF N QEE  GV+ST  IRNGDWTFQ +VMLE
Sbjct: 135 PSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWTFQILVMLE 194

Query: 189 MTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLR 248
           MTP+ G VYTC V+H SL +P+ VEWRAQSE +  KMLSGI  F+LGLIFL +G++I  R
Sbjct: 195 MTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKMLSGIGGFVLGLIFLGLGLIIHHR 254

Query: 249 AQKG 252
           +QKG
Sbjct: 255 SQKG 258


>gi|239740745 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain isoform 1 [Homo sapiens]
          Length = 266

 Score =  295 bits (755), Expect = 3e-80
 Identities = 144/252 (57%), Positives = 183/252 (72%)

Query: 9   VVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDS 68
           + AL V L  L S +    D+   F+ Q K  C+F NGTE+VQF+ R  +N EE+VRFDS
Sbjct: 12  MAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDS 71

Query: 69  DVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVY 128
           DVG + A+T+LG+P AE WNS+ D+LE  R  VD VCRHNY +G  FTV R+V PEVTVY
Sbjct: 72  DVGEYRAVTELGRPVAESWNSQKDILEDRRGQVDTVCRHNYGVGESFTVQRRVHPEVTVY 131

Query: 129 PERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLE 188
           P +T  L  HNLL CSV+GFYPG I+++WF NGQEE+AGV+STG I+NGDWTFQT+VMLE
Sbjct: 132 PAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLE 191

Query: 189 MTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLR 248
             P  G VYTC V+H S++SP++VEWRA+SE +  KMLSG+  F+LGL+FL  G+ I  R
Sbjct: 192 TVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFR 251

Query: 249 AQKGYVRTQMSG 260
            QKG+   Q +G
Sbjct: 252 NQKGHSGLQPTG 263


>gi|239740695 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain isoform 1 [Homo sapiens]
          Length = 266

 Score =  295 bits (755), Expect = 3e-80
 Identities = 144/252 (57%), Positives = 183/252 (72%)

Query: 9   VVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDS 68
           + AL V L  L S +    D+   F+ Q K  C+F NGTE+VQF+ R  +N EE+VRFDS
Sbjct: 12  MAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDS 71

Query: 69  DVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVY 128
           DVG + A+T+LG+P AE WNS+ D+LE  R  VD VCRHNY +G  FTV R+V PEVTVY
Sbjct: 72  DVGEYRAVTELGRPVAESWNSQKDILEDRRGQVDTVCRHNYGVGESFTVQRRVHPEVTVY 131

Query: 129 PERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLE 188
           P +T  L  HNLL CSV+GFYPG I+++WF NGQEE+AGV+STG I+NGDWTFQT+VMLE
Sbjct: 132 PAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLE 191

Query: 189 MTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLR 248
             P  G VYTC V+H S++SP++VEWRA+SE +  KMLSG+  F+LGL+FL  G+ I  R
Sbjct: 192 TVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFR 251

Query: 249 AQKGYVRTQMSG 260
            QKG+   Q +G
Sbjct: 252 NQKGHSGLQPTG 263


>gi|239748785 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-9 beta chain [Homo sapiens]
          Length = 266

 Score =  293 bits (750), Expect = 1e-79
 Identities = 144/252 (57%), Positives = 184/252 (73%)

Query: 9   VVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDS 68
           + AL V L  L S +    D+   F+ Q K +C+F NGTE+V+++ R I+N EE VRFDS
Sbjct: 12  MAALTVTLMVLSSPLALAGDTQPRFLKQDKFECHFFNGTERVRYLHRGIYNQEENVRFDS 71

Query: 69  DVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVY 128
           DVG + A+T+LG+P AE WNS+ D LER R  VD VCRHNY +G  FTV R+V PEVTVY
Sbjct: 72  DVGEYRAVTELGRPVAESWNSQKDFLERRRAEVDTVCRHNYGVGESFTVQRRVHPEVTVY 131

Query: 129 PERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLE 188
           P +T  L  HNLL CSV+GFYPG I+++WF NGQEE+AGV+STG I+NGDWTFQT+VMLE
Sbjct: 132 PAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLE 191

Query: 189 MTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLR 248
             P  G VYTC V+H S++SP++VEWRA+SE +  KMLSG+  F+LGL+FL  G+ I  R
Sbjct: 192 TVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFR 251

Query: 249 AQKGYVRTQMSG 260
            QKG+   Q +G
Sbjct: 252 NQKGHSGLQPTG 263


>gi|52630344 major histocompatibility complex, class II, DR beta 4
           precursor [Homo sapiens]
          Length = 266

 Score =  292 bits (748), Expect = 2e-79
 Identities = 140/252 (55%), Positives = 185/252 (73%)

Query: 9   VVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDS 68
           + AL V LT L S +    D+   F+ QAK +C+F NGTE+V  ++R+I+N EEY R++S
Sbjct: 12  MAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYIYNQEEYARYNS 71

Query: 69  DVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVY 128
           D+G + A+T+LG+PDAE WNS+ DLLER R  VD  CR+NY +   FTV R+VQP+VTVY
Sbjct: 72  DLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTVQRRVQPKVTVY 131

Query: 129 PERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLE 188
           P +T  L  HNLL CSV GFYPG I+++WF NGQEE+AGV+STG I+NGDWTFQT+VMLE
Sbjct: 132 PSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLE 191

Query: 189 MTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLR 248
             P  G VYTC V+H S++SP++V+W A+SE +  KMLSG+  F+LGL+FL  G+ I  R
Sbjct: 192 TVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLLFLGTGLFIYFR 251

Query: 249 AQKGYVRTQMSG 260
            QKG+   Q +G
Sbjct: 252 NQKGHSGLQPTG 263


>gi|239748820 PREDICTED: hypothetical protein XP_002346811 [Homo
           sapiens]
          Length = 266

 Score =  288 bits (738), Expect = 3e-78
 Identities = 141/252 (55%), Positives = 179/252 (71%)

Query: 9   VVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDS 68
           +  L V L  L S +    D+   F+ + K +C+F NGTE+V+ + R+  N EE VRFDS
Sbjct: 12  MAVLTVTLMVLSSPLALAGDTRPRFLEEVKFECHFFNGTERVRLLERYFHNQEENVRFDS 71

Query: 69  DVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVY 128
           DVG F A+T+LG+PDAE WNS+ DLLE+ R AVD  CRHNY +G  FTV R+V P+VTVY
Sbjct: 72  DVGEFRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVHPKVTVY 131

Query: 129 PERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLE 188
           P +T  L  HNLL CSV+GFYPG I+++WF NGQEE+ GV+STG I NGDWTFQT+VMLE
Sbjct: 132 PSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNGDWTFQTLVMLE 191

Query: 189 MTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLR 248
             P  G VYTC V+H S+ SP++VEWRA+SE +  KMLSG+  F+LGL+FL  G+ I  R
Sbjct: 192 TVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFR 251

Query: 249 AQKGYVRTQMSG 260
            QKG+   Q  G
Sbjct: 252 NQKGHSGLQPRG 263


>gi|239740853 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 2 [Homo sapiens]
          Length = 266

 Score =  287 bits (735), Expect = 6e-78
 Identities = 140/252 (55%), Positives = 180/252 (71%)

Query: 9   VVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDS 68
           + AL V L  L S +    D+   F+   K++C+F NGTE+V+F+ R   N EEY RFDS
Sbjct: 12  LAALTVTLMVLSSRLAFAGDTRPRFLELLKSECHFFNGTERVRFLERHFHNQEEYARFDS 71

Query: 69  DVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVY 128
           DVG + A+ +LG+PDAE WNS+ DLLE+ R  VD  CRHNY +G  FTV R+V P+VTVY
Sbjct: 72  DVGEYRAVRELGRPDAEYWNSQKDLLEQKRGQVDNYCRHNYGVGESFTVQRRVHPQVTVY 131

Query: 129 PERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLE 188
           P +T  L  HNLL CSV+GFYPG I+++WF NGQEE+AGV+STG I+NGDWTFQT+VMLE
Sbjct: 132 PAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLE 191

Query: 189 MTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLR 248
             P  G VYTC V+H S+ SP++VEW A+SE +  KMLSG+  F+LGL+FL  G+ I  R
Sbjct: 192 TVPRSGEVYTCQVEHPSVTSPLTVEWSARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFR 251

Query: 249 AQKGYVRTQMSG 260
            QKG+   Q +G
Sbjct: 252 NQKGHSGLQPTG 263


>gi|239740743 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain isoform 2 [Homo sapiens]
          Length = 264

 Score =  287 bits (735), Expect = 6e-78
 Identities = 137/228 (60%), Positives = 173/228 (75%)

Query: 33  FVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDSDVGMFVALTKLGQPDAEQWNSRLD 92
           F+ Q K  C+F NGTE+VQF+ R  +N EE+VRFDSDVG + A+T+LG+P AE WNS+ D
Sbjct: 34  FLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKD 93

Query: 93  LLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVYPERTPLLHQHNLLHCSVTGFYPGD 152
           +LE  R  VD VCRHNY +G  FTV R+V PEVTVYP +T  L  HNLL CSV+GFYPG 
Sbjct: 94  ILEDRRGQVDTVCRHNYGVGESFTVQRRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGS 153

Query: 153 IKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLEMTPELGHVYTCLVDHSSLLSPVSV 212
           I+++WF NGQEE+AGV+STG I+NGDWTFQT+VMLE  P  G VYTC V+H S++SP++V
Sbjct: 154 IEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTV 213

Query: 213 EWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLRAQKGYVRTQMSG 260
           EWRA+SE +  KMLSG+  F+LGL+FL  G+ I  R QKG+   Q +G
Sbjct: 214 EWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTG 261


>gi|239740693 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain isoform 2 [Homo sapiens]
          Length = 264

 Score =  287 bits (735), Expect = 6e-78
 Identities = 137/228 (60%), Positives = 173/228 (75%)

Query: 33  FVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDSDVGMFVALTKLGQPDAEQWNSRLD 92
           F+ Q K  C+F NGTE+VQF+ R  +N EE+VRFDSDVG + A+T+LG+P AE WNS+ D
Sbjct: 34  FLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKD 93

Query: 93  LLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVYPERTPLLHQHNLLHCSVTGFYPGD 152
           +LE  R  VD VCRHNY +G  FTV R+V PEVTVYP +T  L  HNLL CSV+GFYPG 
Sbjct: 94  ILEDRRGQVDTVCRHNYGVGESFTVQRRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGS 153

Query: 153 IKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLEMTPELGHVYTCLVDHSSLLSPVSV 212
           I+++WF NGQEE+AGV+STG I+NGDWTFQT+VMLE  P  G VYTC V+H S++SP++V
Sbjct: 154 IEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTV 213

Query: 213 EWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLRAQKGYVRTQMSG 260
           EWRA+SE +  KMLSG+  F+LGL+FL  G+ I  R QKG+   Q +G
Sbjct: 214 EWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTG 261


>gi|18641375 major histocompatibility complex, class II, DR beta 5
           precursor [Homo sapiens]
          Length = 266

 Score =  287 bits (735), Expect = 6e-78
 Identities = 140/246 (56%), Positives = 179/246 (72%)

Query: 8   WVVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFD 67
           ++  L V L  L S +    D+   F+ Q K +C+F NGTE+V+F+ R I+N EE +RFD
Sbjct: 11  YMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLHRDIYNQEEDLRFD 70

Query: 68  SDVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTV 127
           SDVG + A+T+LG+PDAE WNS+ D LE  R AVD  CRHNY +G  FTV R+V+P+VTV
Sbjct: 71  SDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTVQRRVEPKVTV 130

Query: 128 YPERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVML 187
           YP RT  L  HNLL CSV GFYPG I+++WF N QEE+AGV+STG I+NGDWTFQT+VML
Sbjct: 131 YPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNGDWTFQTLVML 190

Query: 188 EMTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQL 247
           E  P  G VYTC V+H S+ SP++VEWRAQSE +  KMLSG+  F+LGL+FL  G+ I  
Sbjct: 191 ETVPRSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLGLLFLGAGLFIYF 250

Query: 248 RAQKGY 253
           + QKG+
Sbjct: 251 KNQKGH 256


>gi|17986005 major histocompatibility complex, class II, DR beta 3
           precursor [Homo sapiens]
          Length = 266

 Score =  285 bits (728), Expect = 4e-77
 Identities = 138/252 (54%), Positives = 182/252 (72%)

Query: 9   VVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDS 68
           + AL V L  L S +    D+   F+   K++C+F NGTE+V+++ R+  N EE++RFDS
Sbjct: 12  LAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYFHNQEEFLRFDS 71

Query: 69  DVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVY 128
           DVG + A+T+LG+P AE WNS+ DLLE+ R  VD  CRHNY +G  FTV R+V P+VTVY
Sbjct: 72  DVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTVQRRVHPQVTVY 131

Query: 129 PERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLE 188
           P +T  L  HNLL CSV+GFYPG I+++WF NGQEE+AGV+STG I+NGDWTFQT+VMLE
Sbjct: 132 PAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLE 191

Query: 189 MTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLR 248
             P  G VYTC V+H S+ S ++VEWRA+SE +  KMLSG+  F+LGL+FL  G+ I  R
Sbjct: 192 TVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFR 251

Query: 249 AQKGYVRTQMSG 260
            QKG+   Q +G
Sbjct: 252 NQKGHSGLQPTG 263


>gi|239740857 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 2 [Homo sapiens]
          Length = 266

 Score =  283 bits (723), Expect = 1e-76
 Identities = 138/252 (54%), Positives = 178/252 (70%)

Query: 9   VVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDS 68
           +  L V L  L S +    D+   F+  + ++C+F NGTE+V+++ R+  N EE VRFDS
Sbjct: 12  MAVLTVTLMVLSSPLALAGDTRPRFLEYSTSECHFFNGTERVRYLDRYFHNQEENVRFDS 71

Query: 69  DVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVY 128
           DVG F A+T+LG+PDAE WNS+ DLLE+ R  VD  CRHNY +   FTV R+V P+VTVY
Sbjct: 72  DVGEFRAVTELGRPDAEYWNSQKDLLEQKRGRVDNYCRHNYGVVESFTVQRRVHPKVTVY 131

Query: 129 PERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLE 188
           P +T  L  HNLL CSV+GFYPG I+++WF NGQEE+ GV+STG I NGDWTFQT+VMLE
Sbjct: 132 PSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNGDWTFQTLVMLE 191

Query: 189 MTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLR 248
             P  G VYTC V+H S+ SP++VEWRA+SE +  KMLSG+  F+LGL+FL  G+ I  R
Sbjct: 192 TVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFR 251

Query: 249 AQKGYVRTQMSG 260
            QKG+   Q  G
Sbjct: 252 NQKGHSGLQPRG 263


>gi|239758090 PREDICTED: major histocompatibility complex, class II,
           DR beta 4 [Homo sapiens]
          Length = 278

 Score =  282 bits (722), Expect = 2e-76
 Identities = 132/228 (57%), Positives = 174/228 (76%)

Query: 33  FVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDSDVGMFVALTKLGQPDAEQWNSRLD 92
           F+ QAK +C+F NGTE+V  ++R+I+N EEY R++SD+G + A+T+LG+PDAE WNS+ D
Sbjct: 48  FLEQAKCECHFLNGTERVWNLIRYIYNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKD 107

Query: 93  LLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVYPERTPLLHQHNLLHCSVTGFYPGD 152
           LLER R  VD  CR+NY +   FTV R+VQP+VTVYP +T  L  HNLL CSV GFYPG 
Sbjct: 108 LLERRRAEVDTYCRYNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGS 167

Query: 153 IKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLEMTPELGHVYTCLVDHSSLLSPVSV 212
           I+++WF NGQEE+AGV+STG I+NGDWTFQT+VMLE  P  G VYTC V+H S++SP++V
Sbjct: 168 IEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTV 227

Query: 213 EWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLRAQKGYVRTQMSG 260
           +W A+SE +  KMLSG+  F+LGL+FL  G+ I  R QKG+   Q +G
Sbjct: 228 QWSARSESAQSKMLSGVGGFVLGLLFLGTGLFIYFRNQKGHSGLQPTG 275


>gi|239740855 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 1 [Homo sapiens]
          Length = 267

 Score =  282 bits (721), Expect = 3e-76
 Identities = 139/253 (54%), Positives = 179/253 (70%), Gaps = 1/253 (0%)

Query: 9   VVALLVNLTRLDSSMTQGTDSPEDFVIQA-KADCYFTNGTEKVQFVVRFIFNLEEYVRFD 67
           + AL V L  L S +    D+     +   K++C+F NGTE+V+F+ R   N EEY RFD
Sbjct: 12  LAALTVTLMVLSSRLAFAGDTRRKSTLWLLKSECHFFNGTERVRFLERHFHNQEEYARFD 71

Query: 68  SDVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTV 127
           SDVG + A+ +LG+PDAE WNS+ DLLE+ R  VD  CRHNY +G  FTV R+V P+VTV
Sbjct: 72  SDVGEYRAVRELGRPDAEYWNSQKDLLEQKRGQVDNYCRHNYGVGESFTVQRRVHPQVTV 131

Query: 128 YPERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVML 187
           YP +T  L  HNLL CSV+GFYPG I+++WF NGQEE+AGV+STG I+NGDWTFQT+VML
Sbjct: 132 YPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVML 191

Query: 188 EMTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQL 247
           E  P  G VYTC V+H S+ SP++VEW A+SE +  KMLSG+  F+LGL+FL  G+ I  
Sbjct: 192 ETVPRSGEVYTCQVEHPSVTSPLTVEWSARSESAQSKMLSGVGGFVLGLLFLGAGLFIYF 251

Query: 248 RAQKGYVRTQMSG 260
           R QKG+   Q +G
Sbjct: 252 RNQKGHSGLQPTG 264


>gi|239740859 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 1 [Homo sapiens]
          Length = 267

 Score =  276 bits (707), Expect = 1e-74
 Identities = 137/253 (54%), Positives = 176/253 (69%), Gaps = 1/253 (0%)

Query: 9   VVALLVNLTRLDSSMTQGTDSPEDFVIQAK-ADCYFTNGTEKVQFVVRFIFNLEEYVRFD 67
           +  L V L  L S +    D+     +    ++C+F NGTE+V+++ R+  N EE VRFD
Sbjct: 12  MAVLTVTLMVLSSPLALAGDTRRKCTLWVPTSECHFFNGTERVRYLDRYFHNQEENVRFD 71

Query: 68  SDVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTV 127
           SDVG F A+T+LG+PDAE WNS+ DLLE+ R  VD  CRHNY +   FTV R+V P+VTV
Sbjct: 72  SDVGEFRAVTELGRPDAEYWNSQKDLLEQKRGRVDNYCRHNYGVVESFTVQRRVHPKVTV 131

Query: 128 YPERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVML 187
           YP +T  L  HNLL CSV+GFYPG I+++WF NGQEE+ GV+STG I NGDWTFQT+VML
Sbjct: 132 YPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNGDWTFQTLVML 191

Query: 188 EMTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQL 247
           E  P  G VYTC V+H S+ SP++VEWRA+SE +  KMLSG+  F+LGL+FL  G+ I  
Sbjct: 192 ETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYF 251

Query: 248 RAQKGYVRTQMSG 260
           R QKG+   Q  G
Sbjct: 252 RNQKGHSGLQPRG 264


>gi|24797076 major histocompatibility complex, class II, DP beta 1
           precursor [Homo sapiens]
          Length = 258

 Score =  273 bits (699), Expect = 9e-74
 Identities = 135/245 (55%), Positives = 175/245 (71%), Gaps = 2/245 (0%)

Query: 7   PWVVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRF 66
           P  VAL   L  L +S+ QG  +PE+++ Q + +CY  NGT++  F+ R+I+N EE+ RF
Sbjct: 10  PRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQR--FLERYIYNREEFARF 67

Query: 67  DSDVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVT 126
           DSDVG F A+T+LG+P AE WNS+ D+LE  R   D +CRHNY LG P T+ R+VQP V 
Sbjct: 68  DSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTLQRRVQPRVN 127

Query: 127 VYPERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVM 186
           V P +   L  HNLL C VT FYPG I+++WFLNGQEE AGV+ST  IRNGDWTFQ +VM
Sbjct: 128 VSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWTFQILVM 187

Query: 187 LEMTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQ 246
           LEMTP+ G VYTC V+H+SL SPV+VEW+AQS+ +  K L+G   F+LGLI   VGI + 
Sbjct: 188 LEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLIICGVGIFMH 247

Query: 247 LRAQK 251
            R++K
Sbjct: 248 RRSKK 252


>gi|239758092 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain [Homo sapiens]
          Length = 253

 Score =  246 bits (629), Expect = 1e-65
 Identities = 130/252 (51%), Positives = 167/252 (66%), Gaps = 13/252 (5%)

Query: 9   VVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDS 68
           + AL V L  L S +    D+   F+ Q K  C+F NGTE+VQF+ R  +N EE+VRFDS
Sbjct: 12  MAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDS 71

Query: 69  DVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVY 128
           DVG + A+T+LG+P AEQ   + DLL          C  +     P      V PEVTVY
Sbjct: 72  DVGEYRAVTELGRPVAEQKTKQGDLL----------CLPD---SFPLPCFLLVHPEVTVY 118

Query: 129 PERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLE 188
           P +T  L  HNLL CSV+GFYPG I+++WF NGQEE+AGV+STG I+NGDWTFQT+VMLE
Sbjct: 119 PAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLE 178

Query: 189 MTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLR 248
             P  G VYTC V+H S++SP++VEWRA+SE +  KMLSG+  F+LGL+FL  G+ I  R
Sbjct: 179 TVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFR 238

Query: 249 AQKGYVRTQMSG 260
            QKG+   Q +G
Sbjct: 239 NQKGHSGLQPTG 250


>gi|169217452 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-4 beta chain, partial [Homo sapiens]
          Length = 223

 Score =  240 bits (612), Expect = 1e-63
 Identities = 112/179 (62%), Positives = 138/179 (77%)

Query: 30  PEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDSDVGMFVALTKLGQPDAEQWNS 89
           P  F+ Q K +C+F NGTE+V+F+ R+ ++ EEYVRFDSDVG + A+T+LG+PDAE WNS
Sbjct: 45  PARFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVTELGRPDAEYWNS 104

Query: 90  RLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVYPERTPLLHQHNLLHCSVTGFY 149
           + DLLE+ R AVD  CRHNY +G  FTV R+V PEVTVYP +T  L  HNLL CSV GFY
Sbjct: 105 QKDLLEQKRAAVDTYCRHNYGVGESFTVQRRVYPEVTVYPAKTQPLQHHNLLVCSVNGFY 164

Query: 150 PGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLEMTPELGHVYTCLVDHSSLLS 208
           PG I+++WF NGQEE+ GV+STG I+NGDWTFQT+VMLE  P  G VYTC V+H SL S
Sbjct: 165 PGSIEVRWFRNGQEEKTGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSLTS 223


>gi|169168671 PREDICTED: similar to MHC class II antigen [Homo
           sapiens]
          Length = 241

 Score =  170 bits (430), Expect = 1e-42
 Identities = 79/142 (55%), Positives = 105/142 (73%)

Query: 120 KVQPEVTVYPERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDW 179
           ++QP+ T+YP +T  LH  N L CSV+GFYPG I+++WF NGQEE+A V+S G I+NGDW
Sbjct: 98  ELQPKGTMYPAKTEPLHHRNPLVCSVSGFYPGSIEVRWFQNGQEEKAAVVSIGLIQNGDW 157

Query: 180 TFQTVVMLEMTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFL 239
           TFQT+VMLE  P  G VYTC V+H S+ SP++VEW A++E +  KMLSG+  F+LGL+FL
Sbjct: 158 TFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWSARTESAQSKMLSGVGGFVLGLLFL 217

Query: 240 LVGIVIQLRAQKGYVRTQMSGN 261
             G+ I  R QKG+   Q +GN
Sbjct: 218 GTGLFIYFRNQKGHSGLQPTGN 239


>gi|169168589 PREDICTED: similar to MHC class II antigen [Homo
           sapiens]
          Length = 140

 Score =  115 bits (289), Expect = 3e-26
 Identities = 56/112 (50%), Positives = 78/112 (69%)

Query: 9   VVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDS 68
           + AL V LT L S +    D+   F+ QAK +C+F NGTE+V  ++R+I+N EEY R++S
Sbjct: 12  MAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYIYNQEEYARYNS 71

Query: 69  DVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRK 120
           D+G + A+T+LG+PDAE WNS+ DLLER R  VD  CR+NY +   FTV R+
Sbjct: 72  DLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTVQRR 123


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,275,966
Number of Sequences: 37866
Number of extensions: 440541
Number of successful extensions: 1006
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 86
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 863
Number of HSP's gapped (non-prelim): 129
length of query: 273
length of database: 18,247,518
effective HSP length: 101
effective length of query: 172
effective length of database: 14,423,052
effective search space: 2480764944
effective search space used: 2480764944
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.