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Search of human proteins with 41281828
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41281828 NADPH oxidase organizer 1 isoform c [Homo sapiens]
(376 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41281828 NADPH oxidase organizer 1 isoform c [Homo sapiens] 764 0.0
gi|41281811 NADPH oxidase organizer 1 isoform b [Homo sapiens] 749 0.0
gi|21389405 NADPH oxidase organizer 1 isoform a [Homo sapiens] 743 0.0
gi|115298672 neutrophil cytosolic factor 1 [Homo sapiens] 106 3e-23
gi|55749544 SH3 multiple domains 1 [Homo sapiens] 94 2e-19
gi|63055059 SH3 and PX domains 2B [Homo sapiens] 84 3e-16
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 49 1e-05
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 49 1e-05
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 48 1e-05
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 48 1e-05
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 48 1e-05
gi|52630425 NCK adaptor protein 2 isoform A [Homo sapiens] 45 8e-05
gi|52630423 NCK adaptor protein 2 isoform A [Homo sapiens] 45 8e-05
gi|28875786 FCH and double SH3 domains 1 [Homo sapiens] 45 8e-05
gi|4505195 mitogen-activated protein kinase kinase kinase 11 [Ho... 45 1e-04
gi|5453754 NCK adaptor protein 1 [Homo sapiens] 43 4e-04
gi|4885153 v-crk sarcoma virus CT10 oncogene homolog (avian)-lik... 42 0.001
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H... 42 0.001
gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens] 42 0.001
gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens] 42 0.001
gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens] 42 0.001
gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sap... 41 0.002
gi|52421790 mitogen-activated protein kinase kinase kinase 9 [Ho... 40 0.003
gi|23308553 spermatogenesis associated 13 [Homo sapiens] 40 0.003
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 40 0.004
gi|39752673 SH3 and cysteine rich domain 2 [Homo sapiens] 40 0.004
gi|182765466 FCH and double SH3 domains 2 [Homo sapiens] 39 0.006
gi|157266298 anti-Mullerian hormone [Homo sapiens] 39 0.008
gi|155723000 mixed lineage kinase 4 [Homo sapiens] 39 0.008
gi|23510413 sorting nexin 26 [Homo sapiens] 39 0.010
>gi|41281828 NADPH oxidase organizer 1 isoform c [Homo sapiens]
Length = 376
Score = 764 bits (1973), Expect = 0.0
Identities = 376/376 (100%), Positives = 376/376 (100%)
Query: 1 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA 60
MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA
Sbjct: 1 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA 60
Query: 61 GLLRRSDRVLPKLLGQASLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI 120
GLLRRSDRVLPKLLGQASLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI
Sbjct: 61 GLLRRSDRVLPKLLGQASLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI 120
Query: 121 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR 180
TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR
Sbjct: 121 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR 180
Query: 181 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP 240
DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP
Sbjct: 181 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP 240
Query: 241 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL 300
QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL
Sbjct: 241 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL 300
Query: 301 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG 360
SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG
Sbjct: 301 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG 360
Query: 361 RPRGCVDSVPHPTTEQ 376
RPRGCVDSVPHPTTEQ
Sbjct: 361 RPRGCVDSVPHPTTEQ 376
>gi|41281811 NADPH oxidase organizer 1 isoform b [Homo sapiens]
Length = 371
Score = 749 bits (1934), Expect = 0.0
Identities = 371/376 (98%), Positives = 371/376 (98%), Gaps = 5/376 (1%)
Query: 1 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA 60
MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA
Sbjct: 1 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA 60
Query: 61 GLLRRSDRVLPKLLGQASLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI 120
GLLRRSDRVLPKLL DAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI
Sbjct: 61 GLLRRSDRVLPKLL-----DAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI 115
Query: 121 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR 180
TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR
Sbjct: 116 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR 175
Query: 181 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP 240
DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP
Sbjct: 176 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP 235
Query: 241 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL 300
QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL
Sbjct: 236 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL 295
Query: 301 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG 360
SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG
Sbjct: 296 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG 355
Query: 361 RPRGCVDSVPHPTTEQ 376
RPRGCVDSVPHPTTEQ
Sbjct: 356 RPRGCVDSVPHPTTEQ 371
>gi|21389405 NADPH oxidase organizer 1 isoform a [Homo sapiens]
Length = 370
Score = 743 bits (1917), Expect = 0.0
Identities = 370/376 (98%), Positives = 370/376 (98%), Gaps = 6/376 (1%)
Query: 1 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA 60
MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLK TLKETFPVEA
Sbjct: 1 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLK-TLKETFPVEA 59
Query: 61 GLLRRSDRVLPKLLGQASLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI 120
GLLRRSDRVLPKLL DAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI
Sbjct: 60 GLLRRSDRVLPKLL-----DAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI 114
Query: 121 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR 180
TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR
Sbjct: 115 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR 174
Query: 181 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP 240
DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP
Sbjct: 175 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP 234
Query: 241 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL 300
QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL
Sbjct: 235 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL 294
Query: 301 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG 360
SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG
Sbjct: 295 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG 354
Query: 361 RPRGCVDSVPHPTTEQ 376
RPRGCVDSVPHPTTEQ
Sbjct: 355 RPRGCVDSVPHPTTEQ 370
>gi|115298672 neutrophil cytosolic factor 1 [Homo sapiens]
Length = 390
Score = 106 bits (265), Expect = 3e-23
Identities = 92/376 (24%), Positives = 152/376 (40%), Gaps = 62/376 (16%)
Query: 24 FAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEAGLLRRSDRVLPKLLGQASLDAPL 83
+ F V+W D S+ V R + E + KTLKE FP+EAG + +R++P L D
Sbjct: 26 YMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPIEAGAINPENRIIPHLPAPKWFDGQ- 84
Query: 84 LGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTITGFFAPQPLDLEPALPPGSRVIL 143
R +G L Y L++ +++R P + FF +P DL+ LP ++
Sbjct: 85 --RAAENRQG-----TLTEYCGTLMSLPTKISRCPHLLDFFKVRPDDLK--LPTDNQTKK 135
Query: 144 PTPEEQPLSRAAGRLSIHS-LEAQSLRCLQPFCTQDTRDRPFQAQAQESLDVLLRHPSGW 202
P P + I + Q+ R + + + T + ++V+ + SGW
Sbjct: 136 PETYLMPKDGKSTATDITGPIILQTYRAIANY--EKTSGSEMALSTGDVVEVVEKSESGW 193
Query: 203 WLVENEDRQTAWFPAPYLEEA-APGQGREGGPSLGSSGPQFCASRAYESSRADELSVPAG 261
W + + ++ W PA +LE +P + + P+ +G + A +AY + DE+S+ G
Sbjct: 194 WFCQMKAKR-GWIPASFLEPLDSPDETEDPEPNY--AGEPYVAIKAYTAVEGDEVSLLEG 250
Query: 262 ARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALLSGTGFRGGDDP---------- 311
V V+ GWW+ R D G P++ L+ G + + G P
Sbjct: 251 EAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHS 310
Query: 312 -------------------------AGEARGFPE----------PSQATAPPPTVPTRPS 336
+AR P+ +Q + P P VP RPS
Sbjct: 311 IHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSKPQPAVPPRPS 370
Query: 337 PGAIQSRCCTVTRRAL 352
I +RC T+R L
Sbjct: 371 ADLILNRCSESTKRKL 386
>gi|55749544 SH3 multiple domains 1 [Homo sapiens]
Length = 1105
Score = 94.4 bits (233), Expect = 2e-19
Identities = 74/297 (24%), Positives = 126/297 (42%), Gaps = 23/297 (7%)
Query: 10 VQGAALVQIKRLQT------FAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEAGLL 63
VQ A +V +++ + + +V WSD + + R + +F L+ L + FP+E G
Sbjct: 6 VQDATVVDVEKRRNPSKHYVYIINVTWSDSTSQTIYRRYSKFFDLQMQLLDKFPIEGGQK 65
Query: 64 RRSDRVLPKLLGQASLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTITGF 123
R++P L G+ L R + RL+ ++ Y R L+ +++ + F
Sbjct: 66 DPKQRIIPFLPGKI-----LFRRSHIRDVAVKRLKPIDEYCRALVRLPPHISQCDEVFRF 120
Query: 124 FAPQPLDLEP-----ALPPGSRVILPTPEEQPLSRAAGR-LSIHSLEAQSLRCLQPFCTQ 177
F +P D+ P V L + E P G + + + + + Q
Sbjct: 121 FEARPEDVNPPKEDYGSSKRKSVWLSSWAESPKKDVTGADATAEPMILEQYVVVSNYKKQ 180
Query: 178 DTRDRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGS 237
+ + QA E +DV+ ++ SGWW V + Q W PA YL EA G + +
Sbjct: 181 ENSE--LSLQAGEVVDVIEKNESGWWFVSTSEEQ-GWVPATYL-EAQNGTRDDSDINTSK 236
Query: 238 SGPQ--FCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLR 292
+G + + + Y S DE+ G V V+ + GWW RY + G PA L+
Sbjct: 237 TGEEEKYVTVQPYTSQSKDEIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPASYLK 293
Score = 45.4 bits (106), Expect = 8e-05
Identities = 28/107 (26%), Positives = 46/107 (42%), Gaps = 15/107 (14%)
Query: 247 AYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLL------RPEGLGALL 300
AY+ + E+S PAG V+VLE + GWW R+G+ G P+ L +P+ G L
Sbjct: 822 AYQKVQDSEISFPAGVEVQVLEKQESGWWYVRFGELEGWAPSHYLVLDENEQPDPSGKEL 881
Query: 301 SGTGFRGGDDPA---------GEARGFPEPSQATAPPPTVPTRPSPG 338
+G + + +Q+ P +P++P G
Sbjct: 882 DTVPAKGRQNEGKSDSLEKIERRVQALNTVNQSKKATPPIPSKPPGG 928
Score = 38.9 bits (89), Expect = 0.008
Identities = 29/113 (25%), Positives = 45/113 (39%), Gaps = 9/113 (7%)
Query: 241 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL 300
Q+ Y+ ELS+ AG V V+E ++ GWW + G +PA L +
Sbjct: 170 QYVVVSNYKKQENSELSLQAGEVVDVIEKNESGWWFVSTSEEQGWVPATYLEAQ------ 223
Query: 301 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALE 353
+GT D ++ E T P T ++ G + V R+ LE
Sbjct: 224 NGT---RDDSDINTSKTGEEEKYVTVQPYTSQSKDEIGFEKGVTVEVIRKNLE 273
Score = 31.6 bits (70), Expect = 1.2
Identities = 13/35 (37%), Positives = 22/35 (62%), Gaps = 3/35 (8%)
Query: 191 SLDVLLRHPSGWW---LVENEDRQTAWFPAPYLEE 222
S++VL R+P+GWW +++ W P+ YLE+
Sbjct: 1069 SMEVLERNPNGWWYCQILDGVKPFKGWVPSNYLEK 1103
>gi|63055059 SH3 and PX domains 2B [Homo sapiens]
Length = 911
Score = 83.6 bits (205), Expect = 3e-16
Identities = 64/276 (23%), Positives = 118/276 (42%), Gaps = 33/276 (11%)
Query: 24 FAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEAGLLRRSDRVLPKLLGQASLDAPL 83
+ V WS GS + R + +F L+ + + FP+E G R++P L G+ L
Sbjct: 27 YIIRVTWSSGSTEAIYRRYSKFFDLQMQMLDKFPMEGGQKDPKQRIIPFLPGKI-----L 81
Query: 84 LGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTITGFFAPQPLDLEPALPPGSRVIL 143
R + RL ++ Y + L+ +++ + FF +P DL P
Sbjct: 82 FRRSHIRDVAVKRLIPIDEYCKALIQLPPYISQCDEVLQFFETRPEDLNP---------- 131
Query: 144 PTPEEQPLSR---AAGRLSIHSLEAQSLRCLQPFCTQDTRDRPFQAQAQESLDVLLRHPS 200
P+E+ + + + S+ + + + + Q++ + + +D++ ++ S
Sbjct: 132 --PKEEHIGKKKSGGDQTSVDPMVLEQYVVVANYQKQESSE--ISLSVGQVVDIIEKNES 187
Query: 201 GWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGPQ----FCASRAYESSRADEL 256
GWW V + Q W PA LE G++G S P+ + Y + DE+
Sbjct: 188 GWWFVSTAEEQ-GWVPATCLE------GQDGVQDEFSLQPEEEEKYTVIYPYTARDQDEM 240
Query: 257 SVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLR 292
++ GA V V++ + GWW RY + G PA L+
Sbjct: 241 NLERGAVVEVIQKNLEGWWKIRYQGKEGWAPASYLK 276
Score = 36.2 bits (82), Expect = 0.049
Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 14/99 (14%)
Query: 248 YESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLL----------RPEGLG 297
++++ D +S AG +V V+E + GWW + D+ G PA + RP L
Sbjct: 379 FQTTIPDGISFQAGLKVEVIEKNLSGWWYIQIEDKEGWAPATFIDKYKKTSNASRPNFLA 438
Query: 298 AL-LSGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRP 335
L T R G+ A E S+AT P +P P
Sbjct: 439 PLPHEVTQLRLGEAAALENN---TGSEATGPSRPLPDAP 474
Score = 32.7 bits (73), Expect = 0.55
Identities = 12/36 (33%), Positives = 25/36 (69%), Gaps = 1/36 (2%)
Query: 187 QAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEE 222
QA ++V+ ++ SGWW ++ ED++ W PA ++++
Sbjct: 390 QAGLKVEVIEKNLSGWWYIQIEDKE-GWAPATFIDK 424
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 48.5 bits (114), Expect = 1e-05
Identities = 30/101 (29%), Positives = 43/101 (42%), Gaps = 9/101 (8%)
Query: 197 RHPSGWWLVE----NEDRQTAWFPAPYLEEAAPGQGR----EGGPSLGSSGP-QFCASRA 247
++P GWW E + RQ WFPA Y++ +PG + E S + Q
Sbjct: 1106 KNPGGWWEGELQARGKKRQIGWFPANYVKLLSPGTSKITPTEPPKSTALAAVCQVIGMYD 1165
Query: 248 YESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPA 288
Y + DEL+ G + VL D WW + GL P+
Sbjct: 1166 YTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPS 1206
Score = 42.7 bits (99), Expect = 5e-04
Identities = 32/117 (27%), Positives = 47/117 (40%), Gaps = 21/117 (17%)
Query: 195 LLRHPSGWWLVENEDRQTAWFPAPYLE-----------------EAAPGQGREGGPSLGS 237
+L WW E + Q WFP Y++ E+ R P+
Sbjct: 942 VLEQQDMWWFGEVQG-QKGWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKP 1000
Query: 238 --SGPQFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLR 292
SG +F A YESS +L+ G + V + D WW GD+AG+ P+ +R
Sbjct: 1001 VVSGEEFIAMYTYESSEQGDLTFQQGDVILVTK-KDGDWWTGTVGDKAGVFPSNYVR 1056
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 48.5 bits (114), Expect = 1e-05
Identities = 30/101 (29%), Positives = 43/101 (42%), Gaps = 9/101 (8%)
Query: 197 RHPSGWWLVE----NEDRQTAWFPAPYLEEAAPGQGR----EGGPSLGSSGP-QFCASRA 247
++P GWW E + RQ WFPA Y++ +PG + E S + Q
Sbjct: 1106 KNPGGWWEGELQARGKKRQIGWFPANYVKLLSPGTSKITPTEPPKSTALAAVCQVIGMYD 1165
Query: 248 YESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPA 288
Y + DEL+ G + VL D WW + GL P+
Sbjct: 1166 YTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPS 1206
Score = 42.7 bits (99), Expect = 5e-04
Identities = 32/117 (27%), Positives = 47/117 (40%), Gaps = 21/117 (17%)
Query: 195 LLRHPSGWWLVENEDRQTAWFPAPYLE-----------------EAAPGQGREGGPSLGS 237
+L WW E + Q WFP Y++ E+ R P+
Sbjct: 942 VLEQQDMWWFGEVQG-QKGWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKP 1000
Query: 238 --SGPQFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLR 292
SG +F A YESS +L+ G + V + D WW GD+AG+ P+ +R
Sbjct: 1001 VVSGEEFIAMYTYESSEQGDLTFQQGDVILVTK-KDGDWWTGTVGDKAGVFPSNYVR 1056
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 48.1 bits (113), Expect = 1e-05
Identities = 30/101 (29%), Positives = 44/101 (43%), Gaps = 10/101 (9%)
Query: 194 VLLRHPSGWWLVE----NEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP--QFCASRA 247
+L ++ SGWW E + RQ WFPA +++ P R + + P Q A
Sbjct: 1055 ILKKNTSGWWQGELQARGKKRQKGWFPASHVKLLGPSSER----ATPAFHPVCQVIAMYD 1110
Query: 248 YESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPA 288
Y ++ DELS G + V+ D WW GL P+
Sbjct: 1111 YAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPS 1151
Score = 42.4 bits (98), Expect = 7e-04
Identities = 37/180 (20%), Positives = 70/180 (38%), Gaps = 28/180 (15%)
Query: 160 IHSLEAQSLRCLQPFCTQDTRDRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPY 219
+ +L+AQ+L C+ + ++ + +L WW E + WFP Y
Sbjct: 871 VENLKAQAL------CSWTAKKDNHLNFSKHDIITVLEQQENWWFGEVHGGR-GWFPKSY 923
Query: 220 LEEAAPGQGREGGP-------------SLGSSGPQFCASRAYESSRADELSVPAGARVRV 266
++ + + P + S G ++ A Y S +L+ G + V
Sbjct: 924 VKIIPGSEVKREEPEALYAAVNKKPTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILV 983
Query: 267 LETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALLSGTGFRGGDDPAGEARGFPEPSQATA 326
+ D WW GDR+G+ P+ ++P+ + G +G + PE +Q T+
Sbjct: 984 TQ-KDGEWWTGSIGDRSGIFPSNYVKPKDQESF-------GSASKSGASNKKPEIAQVTS 1035
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 48.1 bits (113), Expect = 1e-05
Identities = 30/101 (29%), Positives = 44/101 (43%), Gaps = 10/101 (9%)
Query: 194 VLLRHPSGWWLVE----NEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP--QFCASRA 247
+L ++ SGWW E + RQ WFPA +++ P R + + P Q A
Sbjct: 1082 ILKKNTSGWWQGELQARGKKRQKGWFPASHVKLLGPSSER----ATPAFHPVCQVIAMYD 1137
Query: 248 YESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPA 288
Y ++ DELS G + V+ D WW GL P+
Sbjct: 1138 YAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPS 1178
Score = 42.4 bits (98), Expect = 7e-04
Identities = 37/180 (20%), Positives = 70/180 (38%), Gaps = 28/180 (15%)
Query: 160 IHSLEAQSLRCLQPFCTQDTRDRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPY 219
+ +L+AQ+L C+ + ++ + +L WW E + WFP Y
Sbjct: 898 VENLKAQAL------CSWTAKKDNHLNFSKHDIITVLEQQENWWFGEVHGGR-GWFPKSY 950
Query: 220 LEEAAPGQGREGGP-------------SLGSSGPQFCASRAYESSRADELSVPAGARVRV 266
++ + + P + S G ++ A Y S +L+ G + V
Sbjct: 951 VKIIPGSEVKREEPEALYAAVNKKPTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILV 1010
Query: 267 LETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALLSGTGFRGGDDPAGEARGFPEPSQATA 326
+ D WW GDR+G+ P+ ++P+ + G +G + PE +Q T+
Sbjct: 1011 TQ-KDGEWWTGSIGDRSGIFPSNYVKPKDQESF-------GSASKSGASNKKPEIAQVTS 1062
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 48.1 bits (113), Expect = 1e-05
Identities = 30/101 (29%), Positives = 44/101 (43%), Gaps = 10/101 (9%)
Query: 194 VLLRHPSGWWLVE----NEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP--QFCASRA 247
+L ++ SGWW E + RQ WFPA +++ P R + + P Q A
Sbjct: 1082 ILKKNTSGWWQGELQARGKKRQKGWFPASHVKLLGPSSER----ATPAFHPVCQVIAMYD 1137
Query: 248 YESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPA 288
Y ++ DELS G + V+ D WW GL P+
Sbjct: 1138 YAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPS 1178
Score = 42.4 bits (98), Expect = 7e-04
Identities = 37/180 (20%), Positives = 70/180 (38%), Gaps = 28/180 (15%)
Query: 160 IHSLEAQSLRCLQPFCTQDTRDRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPY 219
+ +L+AQ+L C+ + ++ + +L WW E + WFP Y
Sbjct: 898 VENLKAQAL------CSWTAKKDNHLNFSKHDIITVLEQQENWWFGEVHGGR-GWFPKSY 950
Query: 220 LEEAAPGQGREGGP-------------SLGSSGPQFCASRAYESSRADELSVPAGARVRV 266
++ + + P + S G ++ A Y S +L+ G + V
Sbjct: 951 VKIIPGSEVKREEPEALYAAVNKKPTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILV 1010
Query: 267 LETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALLSGTGFRGGDDPAGEARGFPEPSQATA 326
+ D WW GDR+G+ P+ ++P+ + G +G + PE +Q T+
Sbjct: 1011 TQ-KDGEWWTGSIGDRSGIFPSNYVKPKDQESF-------GSASKSGASNKKPEIAQVTS 1062
>gi|52630425 NCK adaptor protein 2 isoform A [Homo sapiens]
Length = 380
Score = 45.4 bits (106), Expect = 8e-05
Identities = 38/151 (25%), Positives = 54/151 (35%), Gaps = 47/151 (31%)
Query: 184 FQAQAQESLDV-------LLRHPSGWWLVENEDRQTAWFPAPYLE--------------- 221
+ AQ + LD+ LL WW V N +T + P+ Y+E
Sbjct: 13 YTAQQDQELDIKKNERLWLLDDSKTWWRVRNAANRTGYVPSNYVERKNSLKKGSLVKNLK 72
Query: 222 ---------------EAAPGQGREGGPSLGSSG---------PQFCASRAYESSRADELS 257
+A+P + SG P F AY + R DELS
Sbjct: 73 DTLGLGKTRRKTSARDASPTPSTDAEYPANGSGADRIYDLNIPAF-VKFAYVAEREDELS 131
Query: 258 VPAGARVRVLETSDRGWWLCRYGDRAGLLPA 288
+ G+RV V+E GWW Y + G P+
Sbjct: 132 LVKGSRVTVMEKCSDGWWRGSYNGQIGWFPS 162
>gi|52630423 NCK adaptor protein 2 isoform A [Homo sapiens]
Length = 380
Score = 45.4 bits (106), Expect = 8e-05
Identities = 38/151 (25%), Positives = 54/151 (35%), Gaps = 47/151 (31%)
Query: 184 FQAQAQESLDV-------LLRHPSGWWLVENEDRQTAWFPAPYLE--------------- 221
+ AQ + LD+ LL WW V N +T + P+ Y+E
Sbjct: 13 YTAQQDQELDIKKNERLWLLDDSKTWWRVRNAANRTGYVPSNYVERKNSLKKGSLVKNLK 72
Query: 222 ---------------EAAPGQGREGGPSLGSSG---------PQFCASRAYESSRADELS 257
+A+P + SG P F AY + R DELS
Sbjct: 73 DTLGLGKTRRKTSARDASPTPSTDAEYPANGSGADRIYDLNIPAF-VKFAYVAEREDELS 131
Query: 258 VPAGARVRVLETSDRGWWLCRYGDRAGLLPA 288
+ G+RV V+E GWW Y + G P+
Sbjct: 132 LVKGSRVTVMEKCSDGWWRGSYNGQIGWFPS 162
>gi|28875786 FCH and double SH3 domains 1 [Homo sapiens]
Length = 690
Score = 45.4 bits (106), Expect = 8e-05
Identities = 37/137 (27%), Positives = 58/137 (42%), Gaps = 17/137 (12%)
Query: 202 WWLVENEDRQTAWFPAPYL---EEAAPGQGREGGPSLGSSGPQFCASR--AYESSRADEL 256
W N+ + + P YL + + P ++ G+ F A +Y A+EL
Sbjct: 506 WVKARNQHGEVGFVPERYLNFPDLSLPESSQDSDNPCGAEPTAFLAQALYSYTGQSAEEL 565
Query: 257 SVPAGARVRVLETS----DRGWWLCRYGDRAGLLPAVLLRPEGLGALLSGTGFRGGDDPA 312
S P GA +R+L + D G+W +G R G+ P++L+ LL G DP
Sbjct: 566 SFPEGALIRLLPRAQDGVDDGFWRGEFGGRVGVFPSLLVE-----ELLGPPGPPELSDP- 619
Query: 313 GEARGFPEPSQATAPPP 329
+ P PS + PP
Sbjct: 620 --EQMLPSPSPPSFSPP 634
>gi|4505195 mitogen-activated protein kinase kinase kinase 11 [Homo
sapiens]
Length = 847
Score = 44.7 bits (104), Expect = 1e-04
Identities = 35/102 (34%), Positives = 44/102 (43%), Gaps = 20/102 (19%)
Query: 226 GQGR-EGGP-SLGSSGPQFCASRAYESSRADELSVPAGARVRVLE-----TSDRGWWLCR 278
G GR EG P + G + P + A YE S DEL++ G RV VL + D GWW +
Sbjct: 28 GGGRPEGSPKAAGYANPVWTALFDYEPSGQDELALRKGDRVEVLSRDAAISGDEGWWAGQ 87
Query: 279 YGDRAGLLPAVLLRPEGLGALLSGTGFRGGDDPAGEARGFPE 320
G + G+ P S RGG P E F E
Sbjct: 88 VGGQVGIFP-------------SNYVSRGGGPPPCEVASFQE 116
Score = 30.8 bits (68), Expect = 2.1
Identities = 32/106 (30%), Positives = 38/106 (35%), Gaps = 15/106 (14%)
Query: 282 RAGLLPAVLLRPEGLGALLS---GTGFRGGDDPAGEARGFPEPSQATAPP---------- 328
RA L LL GLG L G G G+ P P P PP
Sbjct: 643 RALLRGTALLASLGLGRDLQPPGGPGRERGESPTTPPTPTPAPCPTEPPPSPLICFSLKT 702
Query: 329 PTVPTRPSPGAIQSRCCTVTRRALERRPRRQGRPRGCVDSVPHPTT 374
P P P+P + R A + PRR+ PRG S P T+
Sbjct: 703 PDSPPTPAPLLLDLGIPVGQRSA--KSPRREEEPRGGTVSPPPGTS 746
>gi|5453754 NCK adaptor protein 1 [Homo sapiens]
Length = 377
Score = 43.1 bits (100), Expect = 4e-04
Identities = 35/152 (23%), Positives = 52/152 (34%), Gaps = 40/152 (26%)
Query: 184 FQAQAQESLDV-------LLRHPSGWWLVENEDRQTAWFPAPYLEE-------------- 222
+ AQ ++ LD+ LL WW V N +T + P+ Y+E
Sbjct: 13 YVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPSNYVERKNSARKASIVKNLK 72
Query: 223 ------------AAPGQGREGGPSLGSSGPQFCASRA-------YESSRADELSVPAGAR 263
+ P S G + Y + R DELS+ G +
Sbjct: 73 DTLGIGKVKRKPSVPDSASPADDSFVDPGERLYDLNMPAYVKFNYMAEREDELSLIKGTK 132
Query: 264 VRVLETSDRGWWLCRYGDRAGLLPAVLLRPEG 295
V V+E GWW Y + G P+ + EG
Sbjct: 133 VIVMEKCSDGWWRGSYNGQVGWFPSNYVTEEG 164
Score = 31.6 bits (70), Expect = 1.2
Identities = 29/113 (25%), Positives = 44/113 (38%), Gaps = 23/113 (20%)
Query: 194 VLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGPQFC---------- 243
V+ + GWW + + Q WFP+ Y+ E G +GS +
Sbjct: 135 VMEKCSDGWWR-GSYNGQVGWFPSNYVTEEGDS---PLGDHVGSLSEKLAAVVNNLNTGQ 190
Query: 244 ------ASRAYESSRADELSVPAGARVRVLE--TSDRGWWLCR-YGDRAGLLP 287
A + SS +EL+ G + V+E +D WW CR GL+P
Sbjct: 191 VLHVVQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVGLVP 243
>gi|4885153 v-crk sarcoma virus CT10 oncogene homolog (avian)-like
[Homo sapiens]
Length = 303
Score = 42.0 bits (97), Expect = 0.001
Identities = 39/175 (22%), Positives = 64/175 (36%), Gaps = 11/175 (6%)
Query: 104 SRRLLATAERVARSPTITGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSL 163
+RR + P + F+ LD + P R P+P +S A L
Sbjct: 68 NRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRY--PSPPMGSVS--APNLPTAED 123
Query: 164 EAQSLRCLQPFCTQDTRDRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEA 223
+ +R L F D D PF+ E L ++ + WW N+D + P PY+E+
Sbjct: 124 NLEYVRTLYDFPGNDAEDLPFKKG--EILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKL 181
Query: 224 APG-----QGREGGPSLGSSGPQFCASRAYESSRADELSVPAGARVRVLETSDRG 273
G S G P ++ ++ +S GA + L ++ G
Sbjct: 182 VRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNG 236
Score = 36.2 bits (82), Expect = 0.049
Identities = 36/139 (25%), Positives = 55/139 (39%), Gaps = 15/139 (10%)
Query: 209 DRQTAWFPAPYLEEAAPGQGREGGPSLGSSGPQFCASRA---YESSRADELSVPAGARVR 265
D T PAP +P G P+L ++ R + + A++L G +
Sbjct: 94 DTTTLIEPAP--RYPSPPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILV 151
Query: 266 VLETSDRGWWLCRYGD-RAGLLPAVLLRPEGLGALLSGTGFRGGDDPAGEARGFPEPSQA 324
++E + WW R D R G++P + + G R + + G PEP+ A
Sbjct: 152 IIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSPHGKHGNRNSN-----SYGIPEPAHA 206
Query: 325 TAPPPTVPTRP----SPGA 339
A P T P SPGA
Sbjct: 207 YAQPQTTTPLPAVSGSPGA 225
>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
sapiens]
Length = 756
Score = 42.0 bits (97), Expect = 0.001
Identities = 41/156 (26%), Positives = 62/156 (39%), Gaps = 35/156 (22%)
Query: 172 QPFCTQDTRDRPFQA-----QAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPG 226
Q +C + P QA QA E ++++ GWWL + ++ Q FP+ ++E G
Sbjct: 85 QRWCKVNFSYSPEQADELKLQAGEIVEMIKEIEDGWWLGK-KNGQLGAFPSNFVELLDSG 143
Query: 227 QGREGGPSL-----GSSGPQFCASRAYES----------------------SRADELSVP 259
G P + G P +S AY+S DEL++
Sbjct: 144 PPSLGNPDMPSVSPGPQRPPKLSSLAYDSPPDYLQTVSHPEVYRVLFDYQPEAPDELALR 203
Query: 260 AGARVRVLE--TSDRGWWLCRYGDRAGLLPAVLLRP 293
G V+VL T D+GWW R G+ P + P
Sbjct: 204 RGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFVLP 239
Score = 37.0 bits (84), Expect = 0.029
Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Query: 229 REGGPSLGSSGPQFC-ASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLP 287
R G P+ ++C + +Y +ADEL + AG V +++ + GWWL + + G P
Sbjct: 74 RRGHPAKHPRPQRWCKVNFSYSPEQADELKLQAGEIVEMIKEIEDGWWLGKKNGQLGAFP 133
Query: 288 A 288
+
Sbjct: 134 S 134
Score = 30.4 bits (67), Expect = 2.7
Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 3/52 (5%)
Query: 248 YESSRADELSVPAGARVRVLE-TSDRGWWLCRYGDRAGLLPAVLLR--PEGL 296
Y + + DELS+ G VR + RGW +G R GL P L++ PE L
Sbjct: 9 YRAQKEDELSLAPGDVVRQVRWVPARGWLRGEFGGRYGLFPERLVQEIPETL 60
>gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens]
Length = 731
Score = 42.0 bits (97), Expect = 0.001
Identities = 19/50 (38%), Positives = 29/50 (58%)
Query: 244 ASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRP 293
A ++ + +D+LS G R+++LE D W R DR G+ PAV +RP
Sbjct: 609 ALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQDREGIFPAVFVRP 658
>gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens]
Length = 767
Score = 42.0 bits (97), Expect = 0.001
Identities = 19/50 (38%), Positives = 29/50 (58%)
Query: 244 ASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRP 293
A ++ + +D+LS G R+++LE D W R DR G+ PAV +RP
Sbjct: 645 ALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQDREGIFPAVFVRP 694
>gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens]
Length = 790
Score = 42.0 bits (97), Expect = 0.001
Identities = 19/50 (38%), Positives = 29/50 (58%)
Query: 244 ASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRP 293
A ++ + +D+LS G R+++LE D W R DR G+ PAV +RP
Sbjct: 668 ALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQDREGIFPAVFVRP 717
>gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo
sapiens]
Length = 735
Score = 40.8 bits (94), Expect = 0.002
Identities = 43/127 (33%), Positives = 54/127 (42%), Gaps = 25/127 (19%)
Query: 216 PAPYLEEAAPGQGREGGPSLGSSGPQFCASRAYESSRADELSVPAGARVRVLETSDRGWW 275
P P E P Q EG + G+ GP + E+SR S GA ++ LE S R W
Sbjct: 36 PEPSPPEPEP-QAPEGSQA-GAEGPS-----SPEASR----SPARGAYLQSLEPSSRRWV 84
Query: 276 LCRYGDRAGLLPAVLLRPEGLGALLSGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRP 335
L G PA LG + GTG +PAGE P P + PP P P
Sbjct: 85 L------GGAKPA---EDTSLGPGVPGTG-----EPAGEIWYNPIPEEDPRPPAPEPPGP 130
Query: 336 SPGAIQS 342
PG+ +S
Sbjct: 131 QPGSAES 137
>gi|52421790 mitogen-activated protein kinase kinase kinase 9 [Homo
sapiens]
Length = 1118
Score = 40.4 bits (93), Expect = 0.003
Identities = 30/97 (30%), Positives = 44/97 (45%), Gaps = 9/97 (9%)
Query: 221 EEAAPGQGREGGPSLGSSGPQFCASRAYESSRADELSVPAGARVRVLE-----TSDRGWW 275
EEAA G G + P + A YE++ DEL++ G V VL + D GWW
Sbjct: 37 EEAAAAVG-PGELGCDAPLPYWTAVFEYEAAGEDELTLRLGDVVEVLSKDSQVSGDEGWW 95
Query: 276 LCRYGDRAGLLPAVLLRPEGLGALLSGTGFRGGDDPA 312
+ R G+ P+ + P + S GG+DP+
Sbjct: 96 TGQLNQRVGIFPSNYVTPR---SAFSSRCQPGGEDPS 129
>gi|23308553 spermatogenesis associated 13 [Homo sapiens]
Length = 652
Score = 40.0 bits (92), Expect = 0.003
Identities = 32/106 (30%), Positives = 46/106 (43%), Gaps = 11/106 (10%)
Query: 222 EAAPGQGREGGPSLG-----SSGPQFCASRAYESSRAD--ELSVPAGARVRVLETSDRGW 274
+A+P + GG L S G CA ++ D EL AG ++VLE S++ W
Sbjct: 125 QASPRYLQPGGEQLAINELISDGNVVCAEALWDHVTMDDQELGFKAGDVIQVLEASNKDW 184
Query: 275 WLCRYGDRAGLLPAVLLR----PEGLGALLSGTGFRGGDDPAGEAR 316
W R D+ PA +R E L S T D+ A ++R
Sbjct: 185 WWGRSEDKEAWFPASFVRLRVNQEELSENSSSTPSEEQDEEASQSR 230
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo
sapiens]
Length = 2161
Score = 39.7 bits (91), Expect = 0.004
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 13/81 (16%)
Query: 221 EEAAPGQGREGGP--SLGSSGPQ-----------FCASRAYESSRADELSVPAGARVRVL 267
E A G G GGP SLGS G + F A ++Y++ E+S+ G +++VL
Sbjct: 525 EGPAGGTGGSGGPGGSLGSRGRRRKLYSAVPGRSFMAVKSYQAQAEGEISLSKGEKIKVL 584
Query: 268 ETSDRGWWLCRYGDRAGLLPA 288
+ G+W + R G P+
Sbjct: 585 SIGEGGFWEGQVKGRVGWFPS 605
>gi|39752673 SH3 and cysteine rich domain 2 [Homo sapiens]
Length = 411
Score = 39.7 bits (91), Expect = 0.004
Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 2/73 (2%)
Query: 218 PYLEEAAPGQGREGGPSLGSSGPQFCASRAYE--SSRADELSVPAGARVRVLETSDRGWW 275
P EE +PGQ GP + Y+ ++L++ G R+ +++ S+ WW
Sbjct: 271 PGPEEKSPGQQLPKATLRKDVGPMYSYVALYKFLPQENNDLALQPGDRIMLVDDSNEDWW 330
Query: 276 LCRYGDRAGLLPA 288
+ GDR G PA
Sbjct: 331 KGKIGDRVGFFPA 343
>gi|182765466 FCH and double SH3 domains 2 [Homo sapiens]
Length = 740
Score = 39.3 bits (90), Expect = 0.006
Identities = 30/86 (34%), Positives = 39/86 (45%), Gaps = 12/86 (13%)
Query: 248 YESSRADELSVPAGARVRVL---ETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALLSGTG 304
YE DELS P GA +R+L D G+W + R G+ P+VL+ E L A
Sbjct: 578 YEGQTDDELSFPEGAIIRILNKENQDDDGFWEGEFNGRIGVFPSVLV--EELSA------ 629
Query: 305 FRGGDDP-AGEARGFPEPSQATAPPP 329
GD P E + P P + PP
Sbjct: 630 SENGDTPWMREIQISPSPKPHASLPP 655
>gi|157266298 anti-Mullerian hormone [Homo sapiens]
Length = 560
Score = 38.9 bits (89), Expect = 0.008
Identities = 62/230 (26%), Positives = 75/230 (32%), Gaps = 39/230 (16%)
Query: 169 RCLQPFCTQDTRDRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQG 228
R L F +T DR + L LR P G LV + W P P L P G
Sbjct: 95 RDLATFGVCNTGDRQAALPSLRRLGAWLRDPGGQRLVVLHLEEVTWEPTPSLRFQEPPPG 154
Query: 229 REGGPSLG------SSGPQFCASRAYESSRADELSVPAGARVRVLETS-DRGWWLCRYGD 281
G P L GP+ +RA A L R VL G W
Sbjct: 155 GAGPPELALLVLYPGPGPEVTVTRA-GLPGAQSLCPSRDTRYLVLAVDRPAGAW------ 207
Query: 282 RAGLLPAVLLRPEGLGALLSGTGFRG---GDD--------------PAGEARGFPEPSQA 324
G A+ L+P G + LS + GDD P E P Q
Sbjct: 208 -RGSGLALTLQPRGEDSRLSTARLQALLFGDDHRCFTRMTPALLLLPRSEPAPLPAHGQL 266
Query: 325 TA-----PPPTVPTRPSPGAIQSRCCTVTR--RALERRPRRQGRPRGCVD 367
P P+ SP + T+TR RAL P R PR +D
Sbjct: 267 DTVPFPPPRPSAELEESPPSADPFLETLTRLVRALRVPPARASAPRLALD 316
>gi|155723000 mixed lineage kinase 4 [Homo sapiens]
Length = 1036
Score = 38.9 bits (89), Expect = 0.008
Identities = 30/118 (25%), Positives = 43/118 (36%), Gaps = 30/118 (25%)
Query: 223 AAPGQGREGGPSLGSSGPQFCASRAYESSRADELSVPAGARVRVLE-----TSDRGWWLC 277
+A G S + + A YE+ DELS+ G V VL + D GWW
Sbjct: 24 SASSSSTSSGGSASAGAGLWAALYDYEARGEDELSLRRGQLVEVLSQDAAVSGDEGWWAG 83
Query: 278 RYGDRAGLLPAVLLRPEGLGALLSGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRP 335
+ R G+ PA + P P+ + APPP+ P+ P
Sbjct: 84 QVQRRLGIFPANYVAP-------------------------CRPAASPAPPPSRPSSP 116
>gi|23510413 sorting nexin 26 [Homo sapiens]
Length = 1126
Score = 38.5 bits (88), Expect = 0.010
Identities = 36/123 (29%), Positives = 51/123 (41%), Gaps = 15/123 (12%)
Query: 246 RAYESSRADELSVPAGARVRVLE---TSDRGWWLCRYGDRAGLLPAVLLRPEGLGALLSG 302
+ Y + DELS G V V++ T DR WW + G + G P+ + L G
Sbjct: 195 KRYTAQAPDELSFEVGDIVSVIDMPPTEDRSWWRGKRGFQVGFFPSECVE---LFTERPG 251
Query: 303 TGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG-R 361
G + D G G P P ++ VP RP + + + R + RP RQ R
Sbjct: 252 PGLKA--DADGPPCGIPAPQGISSLTSAVP-RP-----RGKLAGLLRTFMRSRPSRQRLR 303
Query: 362 PRG 364
RG
Sbjct: 304 QRG 306
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,448,962
Number of Sequences: 37866
Number of extensions: 1006142
Number of successful extensions: 6717
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 85
Number of HSP's successfully gapped in prelim test: 154
Number of HSP's that attempted gapping in prelim test: 6157
Number of HSP's gapped (non-prelim): 666
length of query: 376
length of database: 18,247,518
effective HSP length: 104
effective length of query: 272
effective length of database: 14,309,454
effective search space: 3892171488
effective search space used: 3892171488
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.