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Search of human proteins with 24497554
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24497554 homeobox A13 [Homo sapiens]
(388 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24497554 homeobox A13 [Homo sapiens] 790 0.0
gi|24497536 homeobox C13 [Homo sapiens] 280 1e-75
gi|116734702 homeobox D13 [Homo sapiens] 272 4e-73
gi|62865866 homeobox B13 [Homo sapiens] 251 6e-67
gi|23510368 homeobox D11 [Homo sapiens] 96 5e-20
gi|194363768 homeobox D9 [Homo sapiens] 89 9e-18
gi|194353946 homeobox D12 [Homo sapiens] 86 7e-17
gi|7657166 homeobox C11 [Homo sapiens] 84 2e-16
gi|15029508 homeobox B9 [Homo sapiens] 84 2e-16
gi|5031759 homeobox A11 [Homo sapiens] 82 6e-16
gi|24497533 homeobox C10 [Homo sapiens] 80 4e-15
gi|27804315 homeobox C12 [Homo sapiens] 79 7e-15
gi|24497547 homeobox C9 [Homo sapiens] 79 9e-15
gi|18959212 GS homeobox 2 [Homo sapiens] 77 2e-14
gi|24497526 homeobox B1 [Homo sapiens] 77 3e-14
gi|182765442 homeobox A10 isoform a [Homo sapiens] 76 5e-14
gi|23510366 homeobox D10 [Homo sapiens] 75 8e-14
gi|23097236 homeobox A9 [Homo sapiens] 75 1e-13
gi|126090909 engrailed homeobox 1 [Homo sapiens] 74 2e-13
gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens] 74 2e-13
gi|24497551 homeobox A10 isoform b [Homo sapiens] 74 3e-13
gi|24497538 homeobox C4 [Homo sapiens] 73 5e-13
gi|24497540 homeobox C4 [Homo sapiens] 73 5e-13
gi|33457326 GS homeobox 1 [Homo sapiens] 72 8e-13
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 72 1e-12
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 72 1e-12
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 72 1e-12
gi|121114296 caudal type homeobox 1 [Homo sapiens] 71 2e-12
gi|169636435 caudal type homeobox 2 [Homo sapiens] 70 4e-12
gi|4885127 caudal type homeobox 4 [Homo sapiens] 70 4e-12
>gi|24497554 homeobox A13 [Homo sapiens]
Length = 388
Score = 790 bits (2039), Expect = 0.0
Identities = 388/388 (100%), Positives = 388/388 (100%)
Query: 1 MTASVLLHPRWIEPTVMFLYDNGGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPH 60
MTASVLLHPRWIEPTVMFLYDNGGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPH
Sbjct: 1 MTASVLLHPRWIEPTVMFLYDNGGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPH 60
Query: 61 PAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAA 120
PAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAA
Sbjct: 61 PAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAA 120
Query: 121 AAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYP 180
AAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYP
Sbjct: 121 AAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYP 180
Query: 181 CARMGPHPNAIKSCAQPASAAAAAAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPY 240
CARMGPHPNAIKSCAQPASAAAAAAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPY
Sbjct: 181 CARMGPHPNAIKSCAQPASAAAAAAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPY 240
Query: 241 HHHQPMPGYLDMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPH 300
HHHQPMPGYLDMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPH
Sbjct: 241 HHHQPMPGYLDMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPH 300
Query: 301 LWKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTN 360
LWKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTN
Sbjct: 301 LWKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTN 360
Query: 361 LSERQVTIWFQNRRVKEKKVINKLKTTS 388
LSERQVTIWFQNRRVKEKKVINKLKTTS
Sbjct: 361 LSERQVTIWFQNRRVKEKKVINKLKTTS 388
>gi|24497536 homeobox C13 [Homo sapiens]
Length = 330
Score = 280 bits (717), Expect = 1e-75
Identities = 183/394 (46%), Positives = 223/394 (56%), Gaps = 80/394 (20%)
Query: 1 MTASVLLHPRWIEPTVMFLYDNGGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPH 60
MT S+LLHPRW E ++M++Y++ +AA + G GGGG
Sbjct: 1 MTTSLLLHPRWPE-SLMYVYED-------------------SAAESGIGGGGGGGGG--- 37
Query: 61 PAAAAAGGNFSVAAAAAA------AAAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPP 114
AGG S A+ A ++ A+ CR+L+ HP P AP AP
Sbjct: 38 -GTGGAGGGCSGASPGKAPSMDGLGSSCPASHCRDLLPHPVLGRP-------PAPLGAPQ 89
Query: 115 SAAAAAAAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGY- 173
A P P EAA+QC+P A SSS A L YGY
Sbjct: 90 GAVYTDI-----------------PAP------EAARQCAPPPAPPTSSS--ATLGYGYP 124
Query: 174 FGSGYYPCARMGPHPNAI-KSCAQPASAAAAAAFADKYMDTAGPA-AEEFSSRAKEFAFY 231
FG YY C R+ + N K CA DKY + +G ++ SSRAKEFAFY
Sbjct: 125 FGGSYYGC-RLSHNVNLQQKPCAYHPG--------DKYPEPSGALPGDDLSSRAKEFAFY 175
Query: 232 HQGYAAGPYHHHQPMPGYLDMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYC 291
+A+ +Q MPGYLD+ VVPG+ G E RH+ L +P+E YQ WAL NGW+ Q+YC
Sbjct: 176 -PSFASS----YQAMPGYLDVSVVPGISGHPEPRHDAL-IPVEGYQHWALSNGWDSQVYC 229
Query: 292 PKEQAQPPHLWKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDK 351
KEQ+Q HLWKS PDVV + SSYRRGRKKRVPYTKVQLKELE+EYA +KFITK+K
Sbjct: 230 SKEQSQSAHLWKSPFPDVVPLQPEVSSYRRGRKKRVPYTKVQLKELEKEYAASKFITKEK 289
Query: 352 RRRISATTNLSERQVTIWFQNRRVKEKKVINKLK 385
RRRISATTNLSERQVTIWFQNRRVKEKKV++K K
Sbjct: 290 RRRISATTNLSERQVTIWFQNRRVKEKKVVSKSK 323
>gi|116734702 homeobox D13 [Homo sapiens]
Length = 343
Score = 272 bits (695), Expect = 4e-73
Identities = 178/357 (49%), Positives = 217/357 (60%), Gaps = 51/357 (14%)
Query: 53 AGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAASAYSSAPGEA 112
A GGG AGG + +++++ AAAAA+ QCR ++ AP+ G S G A
Sbjct: 14 ADGGG--------AGGAPASSSSSSVAAAAASGQCRGFLS--APVFAGTHS------GRA 57
Query: 113 PPSAAAAAAAAAAAAAAA---------AAASSSGGPGPAGPAGAEAAKQC---SPCSAAA 160
+AAAAAAAAAAA+ A +++SSS A A AK+C +P +AAA
Sbjct: 58 AAAAAAAAAAAAAASGFAYPGTSERTGSSSSSSSSAVVAARPEAPPAKECPAPTPAAAAA 117
Query: 161 QSSSGPAALPYGY-FGSGYYPCAR---MGPHPNAIKSCAQPASAAAAAAFADKYMDTAGP 216
S PA L YGY FG+GYY C +G NA+KS A+ +KYMD +G
Sbjct: 118 APPSAPA-LGYGYHFGNGYYSCRMSHGVGLQQNALKSSPH---ASLGGFPVEKYMDVSGL 173
Query: 217 A-----AEEFSSRAKEFAFYHQGYAAGPYHHHQPMPGYLDMPVVPGLGGPGESRHEPLGL 271
A A E +RAKE +FY QGY + PY H +PGY+DM G GE RHE +
Sbjct: 174 ASSSVPANEVPARAKEVSFY-QGYTS-PYQH---VPGYIDMV---STFGSGEPRHEAY-I 224
Query: 272 PMESYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLP-DVVSHPSDASSYRRGRKKRVPYT 330
ME YQ W L NGWN Q+YC K+Q Q H WKS+ P DV + D YRRGRKKRVPYT
Sbjct: 225 SMEGYQSWTLANGWNSQVYCTKDQPQGSHFWKSSFPGDVALNQPDMCVYRRGRKKRVPYT 284
Query: 331 KVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKKVINKLKTT 387
K+QLKELE EYA NKFI KDKRRRISA TNLSERQVTIWFQNRRVK+KK+++KLK T
Sbjct: 285 KLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKKIVSKLKDT 341
>gi|62865866 homeobox B13 [Homo sapiens]
Length = 284
Score = 251 bits (642), Expect = 6e-67
Identities = 138/246 (56%), Positives = 162/246 (65%), Gaps = 18/246 (7%)
Query: 144 PAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGPHPNAIKSCAQPASAAAA 203
P AE KQC PC Q +S PA +PYGYFG GYY C +++K CAQ A+ AA
Sbjct: 54 PGSAEPPKQCHPCPGVPQGTS-PAPVPYGYFGGGYYSCR---VSRSSLKPCAQAATLAA- 108
Query: 204 AAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPYHHHQPMPGYLDMPVVPGLGGPGE 263
Y A EE+ SR EFAFY GY G Y QPM YLD+ VV LG PGE
Sbjct: 109 ------YPAETPTAGEEYPSRPTEFAFY-PGYP-GTY---QPMASYLDVSVVQTLGAPGE 157
Query: 264 SRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLPDVVS-HPSDASSYRRG 322
RH+ L LP++SYQ WAL GWN QM C EQ P WK+ D HP DA ++RRG
Sbjct: 158 PRHDSL-LPVDSYQSWALAGGWNSQMCCQGEQNPPGPFWKAAFADSSGQHPPDACAFRRG 216
Query: 323 RKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKKVIN 382
RKKR+PY+K QL+ELEREYA NKFITKDKRR+ISA T+LSERQ+TIWFQNRRVKEKKV+
Sbjct: 217 RKKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQNRRVKEKKVLA 276
Query: 383 KLKTTS 388
K+K ++
Sbjct: 277 KVKNSA 282
>gi|23510368 homeobox D11 [Homo sapiens]
Length = 338
Score = 95.9 bits (237), Expect = 5e-20
Identities = 97/286 (33%), Positives = 113/286 (39%), Gaps = 58/286 (20%)
Query: 100 GAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAA 159
G A G AP AAAAAAAAAAAAA AA P PAG K P AA
Sbjct: 92 GPGGGGGGAGGYAPYYAAAAAAAAAAAAAEEAAMQRELLP-PAGRRPDVLFKAPEPVCAA 150
Query: 160 AQSSSGPAALPYGYFGSGYYPCARMGPHPNAIKSCAQPASAAAAAAFADKYMDTAGPAAE 219
GPA G + Y R G P F Y GP
Sbjct: 151 PGPPHGPA----GAASNFYSAVGRNGILPQG---------------FDQFYEAAPGPPF- 190
Query: 220 EFSSRAKEFAFYHQGYAAGPYHHHQPMP----GYLDM-PVVPGLGGPGESRHEPLGLPME 274
AGP P P G D G GG G S P
Sbjct: 191 -----------------AGPQPPPPPAPPQPEGAADKGDPRTGAGGGGGS---PCTKATP 230
Query: 275 SYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQL 334
+P G G P +A S A + +R RKKR PYTK Q+
Sbjct: 231 GSEPKGAAEGSGGDGEGPPGEAG------------AEKSSSAVAPQRSRKKRCPYTKYQI 278
Query: 335 KELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKKV 380
+ELERE+ N +I K+KR ++S NL++RQV IWFQNRR+KEKK+
Sbjct: 279 RELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKL 324
Score = 41.2 bits (95), Expect = 0.002
Identities = 51/167 (30%), Positives = 59/167 (35%), Gaps = 30/167 (17%)
Query: 37 GAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAH--- 93
G +A ++ G GGGG AGG AAAAAAAAAAA M
Sbjct: 77 GGGGGGSAGGGSSGGGPGGGG------GGAGGYAPYYAAAAAAAAAAAAAEEAAMQRELL 130
Query: 94 -PAPLAPG----AASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSG-------GPGP 141
PA P A +APG PP A AA+ +A G PGP
Sbjct: 131 PPAGRRPDVLFKAPEPVCAAPG--PPHGPAGAASNFYSAVGRNGILPQGFDQFYEAAPGP 188
Query: 142 --AGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGP 186
AGP P AA + G G G PC + P
Sbjct: 189 PFAGPQPPPPPAPPQPEGAADKGDPRT-----GAGGGGGSPCTKATP 230
Score = 38.9 bits (89), Expect = 0.008
Identities = 54/185 (29%), Positives = 60/185 (32%), Gaps = 42/185 (22%)
Query: 23 GGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAA--- 79
GGG A AAAAAAAAAAA A P PA F AA
Sbjct: 95 GGGGGAGGYAPYYAAAAAAAAAAAAAEEAAMQRELLP-PAGRRPDVLFKAPEPVCAAPGP 153
Query: 80 ---AAAAANQCRNLMAHPAPLAPGAASAYSSAPG-----------EAPPSAAAAA----- 120
A AA+ + + L G Y +APG APP AA
Sbjct: 154 PHGPAGAASNFYSAVGRNGILPQGFDQFYEAAPGPPFAGPQPPPPPAPPQPEGAADKGDP 213
Query: 121 --------------AAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGP 166
A + AA S G GP G AGAE + SA A S
Sbjct: 214 RTGAGGGGGSPCTKATPGSEPKGAAEGSGGDGEGPPGEAGAEKSS-----SAVAPQRSRK 268
Query: 167 AALPY 171
PY
Sbjct: 269 KRCPY 273
>gi|194363768 homeobox D9 [Homo sapiens]
Length = 352
Score = 88.6 bits (218), Expect = 9e-18
Identities = 96/340 (28%), Positives = 136/340 (40%), Gaps = 38/340 (11%)
Query: 48 AAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAASAYSS 107
AA G G G A A G + AA A+ + A + + P P AA+A S
Sbjct: 35 AARFGPPGPGAQGRPAGVADGPAATAAEFASCSFAPRSAVFSASWSAVPSQPPAAAAMSG 94
Query: 108 APGE-APPSAAAAAAAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGP 166
PP AA+A+ + G PG AG G P + SGP
Sbjct: 95 LYHPYVPPPPLAASASEPGRYVRSWMEPLPGFPGGAGGGGGGGGG--GPGRGPSPGPSGP 152
Query: 167 AALPYGYFGSGYYPCARMGPHPNAIKSCAQPASAAAAAAFADKYMDTAGPAAEEFSSRAK 226
A + G P R P P + A S+++ + + A E S
Sbjct: 153 ANGRH----YGIKPETRAAPAP---ATAASTTSSSSTSLSSSSKRTECSVARESQGSSGP 205
Query: 227 EFAF--YHQGYAAGPYHHHQPMPGYLDMPVVPGLGGPGE----SRHEPLGLPMESYQPWA 280
EF+ + Q AA P G + G GG E S H G ++ +
Sbjct: 206 EFSCNSFLQEKAAAATGGTGPGAG---IGAATGTGGSSEPSACSDHPIPGCSLKEEEK-- 260
Query: 281 LPNGWNGQMYCPKEQAQPPHLWKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQLKELERE 340
Q P++Q P+ + ++ R RKKR PYTK Q ELE+E
Sbjct: 261 -------QHSQPQQQQLDPN----------NPAANWIHARSTRKKRCPYTKYQTLELEKE 303
Query: 341 YATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKKV 380
+ N ++T+D+R ++ NL+ERQV IWFQNRR+K KK+
Sbjct: 304 FLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKM 343
Score = 35.8 bits (81), Expect = 0.067
Identities = 35/155 (22%), Positives = 54/155 (34%), Gaps = 5/155 (3%)
Query: 4 SVLLHPRWIEPTVMFLYDNGGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPHPAA 63
S L HP ++ P + + G + + G A G G G P P+
Sbjct: 93 SGLYHP-YVPPPPLAASASEPGRYVRSWMEPLPGFPGGAGGGGGGGGGGPGRGPSPGPSG 151
Query: 64 AAAGGNFSV---AAAAAAAAAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAA 120
A G ++ + AA A A AA+ + + + S + G + P + +
Sbjct: 152 PANGRHYGIKPETRAAPAPATAASTTSSSSTSLSSSSKRTECSVARESQGSSGPEFSCNS 211
Query: 121 AAAAAAAAAAAAASSSGGPGPA-GPAGAEAAKQCS 154
AAAA G G A G G+ CS
Sbjct: 212 FLQEKAAAATGGTGPGAGIGAATGTGGSSEPSACS 246
>gi|194353946 homeobox D12 [Homo sapiens]
Length = 270
Score = 85.5 bits (210), Expect = 7e-17
Identities = 61/204 (29%), Positives = 98/204 (48%), Gaps = 20/204 (9%)
Query: 195 AQPASAAAAAAFADKYMDTAGPAAEEFSSRA----KEFAFYHQGYAAGPYHHHQPMPGYL 250
AQPA A A F+ Y+ +GP + + ++ FY AAGP + P +
Sbjct: 61 AQPAGATAFGGFSQPYLAGSGPLGLQPPTAKDGPEEQAKFYAPEAAAGPEERGRTRPSFA 120
Query: 251 -DMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHL-------- 301
+ + P + ++++ G+ + L G + P +L
Sbjct: 121 PESSLAPAVAALKAAKYDYAGVGRATPGSTTLLQGAPCAPGFKDDTKGPLNLNMTVQAAG 180
Query: 302 ----WKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISA 357
+ +LPD + ++ R RKKR PYTK Q+ ELE E+ N+FI + KR+ +S
Sbjct: 181 VASCLRPSLPDGLPW---GAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSN 237
Query: 358 TTNLSERQVTIWFQNRRVKEKKVI 381
NLS++QV IWFQNRR+K+K+V+
Sbjct: 238 RLNLSDQQVKIWFQNRRMKKKRVV 261
Score = 39.7 bits (91), Expect = 0.005
Identities = 52/170 (30%), Positives = 64/170 (37%), Gaps = 17/170 (10%)
Query: 19 LYDNGGGLVADELNKNMEGA---AAAAAAAAAAAAAGAGG-GGFPHPAAAAAGGNFSVAA 74
L NGG L A GA AA A+ A A AGA GGF P A +G +
Sbjct: 29 LRPNGGQLAALPPISYPRGALPWAATPASCAPAQPAGATAFGGFSQPYLAGSG---PLGL 85
Query: 75 AAAAAAAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAAS 134
A Q + AP AA+ G PS A ++ A A AA AA
Sbjct: 86 QPPTAKDGPEEQAKFY-------APEAAAGPEER-GRTRPSFAPESSLAPAVAALKAAKY 137
Query: 135 SSGGPGPAGPAGAEAAKQCSPCSAA-AQSSSGPAALPYGYFGSGYYPCAR 183
G G A P G+ Q +PC+ + GP L +G C R
Sbjct: 138 DYAGVGRATP-GSTTLLQGAPCAPGFKDDTKGPLNLNMTVQAAGVASCLR 186
>gi|7657166 homeobox C11 [Homo sapiens]
Length = 304
Score = 84.3 bits (207), Expect = 2e-16
Identities = 51/132 (38%), Positives = 70/132 (53%), Gaps = 7/132 (5%)
Query: 251 DMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLPDVV 310
D P P G GE++ EP P A + +E P + V
Sbjct: 164 DPPAEPPCSGKGEAKGEPEAPPASGLASRAEAGA---EAEAEEENTNPSS--SGSAHSVA 218
Query: 311 SHPSD--ASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTI 368
P+ A + R RKKR PY+K Q++ELERE+ N +I K+KR ++S NL++RQV I
Sbjct: 219 KEPAKGAAPNAPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKI 278
Query: 369 WFQNRRVKEKKV 380
WFQNRR+KEKK+
Sbjct: 279 WFQNRRMKEKKL 290
>gi|15029508 homeobox B9 [Homo sapiens]
Length = 250
Score = 84.0 bits (206), Expect = 2e-16
Identities = 70/229 (30%), Positives = 99/229 (43%), Gaps = 27/229 (11%)
Query: 170 PYGYFGSGYYPCARMGPHPNAIK--SCA-QPASAAAAAAFADKYMDTAG-------PAAE 219
P F SG Y +R H ++ SC+ QP + A++A +G P +
Sbjct: 24 PPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFGASWAPLSPHASGSLPSVYHPYIQ 83
Query: 220 EFSSRAKEFAFYHQGYAAGPYHHHQPMPGYLDMPVVPGLGGPGESRHEPLGLPMESYQPW 279
E + P P G + P LG PGE + G P S +
Sbjct: 84 PQGVPPAESRYLRTWLEPAPRGEAAPGQGQAAVKAEPLLGAPGELLKQ--GTPEYSLETS 141
Query: 280 A-----LPN---GWNGQMYCPKEQAQPPHLWKSTLPDVVSHPSDASSYRRGRKKRVPYTK 331
A L N G+ C + + PD + ++ R RKKR PYTK
Sbjct: 142 AGREAVLSNQRPGYGDNKICEGSEDKER-------PDQTNPSANWLHARSSRKKRCPYTK 194
Query: 332 VQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKKV 380
Q ELE+E+ N ++T+D+R ++ NLSERQV IWFQNRR+K KK+
Sbjct: 195 YQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKM 243
>gi|5031759 homeobox A11 [Homo sapiens]
Length = 313
Score = 82.4 bits (202), Expect = 6e-16
Identities = 46/92 (50%), Positives = 63/92 (68%), Gaps = 6/92 (6%)
Query: 293 KEQAQPPHLWKSTLPDVVS-HPSD---ASSYRRGRKKRVPYTKVQLKELEREYATNKFIT 348
KE+ + P S+ P+ S H D SS +R RKKR PYTK Q++ELERE+ + +I
Sbjct: 210 KERRRRPE--SSSSPESSSGHTEDKAGGSSGQRTRKKRCPYTKYQIRELEREFFFSVYIN 267
Query: 349 KDKRRRISATTNLSERQVTIWFQNRRVKEKKV 380
K+KR ++S NL++RQV IWFQNRR+KEKK+
Sbjct: 268 KEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKI 299
Score = 45.1 bits (105), Expect = 1e-04
Identities = 38/128 (29%), Positives = 48/128 (37%), Gaps = 1/128 (0%)
Query: 39 AAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLA 98
A +AA A + + HP A + +S A P LA
Sbjct: 96 APSAAGVPGDVLAKSSANVYHHPTPAVSSNFYSTVGRNGVLPQAFDQFFETAYGTPENLA 155
Query: 99 PGAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSA 158
SA + PP+A A +AAAAAAA A A SSS G G AA +
Sbjct: 156 SSDYPGDKSAE-KGPPAATATSAAAAAAATGAPATSSSDSGGGGGCRETAAAAEEKERRR 214
Query: 159 AAQSSSGP 166
+SSS P
Sbjct: 215 RPESSSSP 222
Score = 29.3 bits (64), Expect = 6.3
Identities = 18/46 (39%), Positives = 23/46 (50%)
Query: 32 NKNMEGAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAA 77
+K+ E AA A +AAAAA A G + + GG AAAA
Sbjct: 162 DKSAEKGPPAATATSAAAAAAATGAPATSSSDSGGGGGCRETAAAA 207
>gi|24497533 homeobox C10 [Homo sapiens]
Length = 342
Score = 79.7 bits (195), Expect = 4e-15
Identities = 73/247 (29%), Positives = 110/247 (44%), Gaps = 32/247 (12%)
Query: 144 PAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGPHPNAIKSCAQPASAAAA 203
P + C SA ++ SGP A Y + P + +G H + S + + + +A
Sbjct: 102 PPSVKEENVCCMYSAEKRAKSGPEAALYSH----PLPESCLGEHEVPVPSYYRASPSYSA 157
Query: 204 AAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPYHHHQPMP---GYLDMPVVPGLGG 260
DK +G A +F A + Q + P H P G + P P
Sbjct: 158 L---DKTPHCSG--ANDFE------APFEQRASLNPRAEHLESPQLGGKVSFPETPKSDS 206
Query: 261 PGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLPDVVSHPSDASSY- 319
S +E +++ Q A P G + KE+A+ T + A +
Sbjct: 207 QTPSPNE-----IKTEQSLAGPKGSPSES--EKERAKAADSSPDTSDNEAKEEIKAENTT 259
Query: 320 ------RRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNR 373
+ GRKKR PYTK Q ELE+E+ N ++T+++R IS T NL++RQV IWFQNR
Sbjct: 260 GNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNR 319
Query: 374 RVKEKKV 380
R+K KK+
Sbjct: 320 RMKLKKM 326
>gi|27804315 homeobox C12 [Homo sapiens]
Length = 282
Score = 79.0 bits (193), Expect = 7e-15
Identities = 35/61 (57%), Positives = 49/61 (80%)
Query: 321 RGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKKV 380
R RKKR PY+K+QL ELE E+ N+FIT+ +RR +S NLS++QV IWFQNRR+K+K++
Sbjct: 213 RSRKKRKPYSKLQLAELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKRL 272
Query: 381 I 381
+
Sbjct: 273 L 273
>gi|24497547 homeobox C9 [Homo sapiens]
Length = 260
Score = 78.6 bits (192), Expect = 9e-15
Identities = 53/132 (40%), Positives = 71/132 (53%), Gaps = 12/132 (9%)
Query: 260 GPGESRHEP---LGLPME--SYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLPDVVSHPS 314
GPGE R P G P E P LP+ + K + + L D + +
Sbjct: 131 GPGEGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKHKEEKADL------DPSNPVA 184
Query: 315 DASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRR 374
+ R RKKR PYTK Q ELE+E+ N ++T+D+R ++ NL+ERQV IWFQNRR
Sbjct: 185 NWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRR 244
Query: 375 VKEKKVINKLKT 386
+K KK +NK KT
Sbjct: 245 MKMKK-MNKEKT 255
>gi|18959212 GS homeobox 2 [Homo sapiens]
Length = 304
Score = 77.4 bits (189), Expect = 2e-14
Identities = 74/248 (29%), Positives = 103/248 (41%), Gaps = 35/248 (14%)
Query: 135 SSGGPG-PAGPAGAEAAKQCSPC-SAAAQSSSGPAALPYGYFGSGYYPCARMGPHPNAIK 192
S GPG P+ +GA C C ++ SS G G G+G G
Sbjct: 44 SVSGPGCPSRKSGAFCV--CPLCVTSHLHSSRGSVGAGSGGAGAGVTGAGGSG------- 94
Query: 193 SCAQPASAAAAAAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPYHHHQPM-PGYLD 251
+ AA A K ++ P +F R A +H +HHHQP PG
Sbjct: 95 -----VAGAAGALPLLKSQFSSAPGDAQFCPRVNH-AHHHHHPPQHHHHHHQPQQPG--- 145
Query: 252 MPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLPDVVS 311
+ LG P + + P +N A P T+
Sbjct: 146 SAAAAAAAAAAAAAAAALGHP-QHHAPVCTATTYN--------VADPRRFHCLTMGG--- 193
Query: 312 HPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQ 371
SDAS G++ R +T QL ELERE+++N ++++ +R I+ NLSE+QV IWFQ
Sbjct: 194 --SDASQVPNGKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQ 251
Query: 372 NRRVKEKK 379
NRRVK KK
Sbjct: 252 NRRVKHKK 259
Score = 43.9 bits (102), Expect = 2e-04
Identities = 35/95 (36%), Positives = 44/95 (46%), Gaps = 6/95 (6%)
Query: 37 GAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAP 96
G+ A + A A GAGG G A A G + + ++A A C +
Sbjct: 74 GSVGAGSGGAGAGVTGAGGSG-----VAGAAGALPLLKSQFSSAPGDAQFCPRVNHAHHH 128
Query: 97 LAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAAAA 131
P + P + P SAAAAAAAAAAAAAAAA
Sbjct: 129 HHPPQHHHHHHQP-QQPGSAAAAAAAAAAAAAAAA 162
Score = 34.3 bits (77), Expect = 0.20
Identities = 20/37 (54%), Positives = 23/37 (62%)
Query: 37 GAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVA 73
G+AAAAAAAAAAAAA A G H A ++VA
Sbjct: 145 GSAAAAAAAAAAAAAAAALGHPQHHAPVCTATTYNVA 181
Score = 30.4 bits (67), Expect = 2.8
Identities = 27/93 (29%), Positives = 39/93 (41%), Gaps = 5/93 (5%)
Query: 117 AAAAAAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGS 176
++ + A + A A + +GG G AG AGA + SA + P +
Sbjct: 71 SSRGSVGAGSGGAGAGVTGAGGSGVAGAAGALPLLKSQFSSAPGDAQFCPRV---NHAHH 127
Query: 177 GYYPCARMGPH--PNAIKSCAQPASAAAAAAFA 207
++P H P S A A+AAAAAA A
Sbjct: 128 HHHPPQHHHHHHQPQQPGSAAAAAAAAAAAAAA 160
>gi|24497526 homeobox B1 [Homo sapiens]
Length = 301
Score = 77.0 bits (188), Expect = 3e-14
Identities = 89/302 (29%), Positives = 117/302 (38%), Gaps = 72/302 (23%)
Query: 96 PLAPGAASAYS--SAPGEAPPSAAAAAAAAAAAAAAAAAASSSGGPGPAG-PAGAEAAKQ 152
PL SAYS SAP PPS+A A + A+ SS +G PA +
Sbjct: 13 PLCNRGPSAYSAHSAPTSFPPSSAQAVDSYASEGRYGGGLSSPAFQQNSGYPAQQPPSTL 72
Query: 153 CSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGP-----HPNAIKSCAQPASAAAAAAFA 207
P ++A S PAA Y S YYP + HP++ A +
Sbjct: 73 GVPFPSSAPSGYAPAACSPSYGPSQYYPLGQSEGDGGYFHPSSY--------GAQLGGLS 124
Query: 208 DKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPYHHHQP----------MPGYLDMPVVPG 257
D Y AG G GPY P P Y D+
Sbjct: 125 DGY--GAG------------------GAGPGPYPPQHPPYGNEQTASFAPAYADLL---- 160
Query: 258 LGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLPDVVSHPSDAS 317
E + P P E P A W K + PP K + P + S PS
Sbjct: 161 ----SEDKETPC--PSEPNTPTARTFDWM------KVKRNPPKTAKVSEPGLGS-PSGL- 206
Query: 318 SYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKE 377
R +T QL ELE+E+ NK++++ +R I+AT L+E QV IWFQNRR+K+
Sbjct: 207 --------RTNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQ 258
Query: 378 KK 379
KK
Sbjct: 259 KK 260
>gi|182765442 homeobox A10 isoform a [Homo sapiens]
Length = 410
Score = 76.3 bits (186), Expect = 5e-14
Identities = 55/169 (32%), Positives = 81/169 (47%), Gaps = 29/169 (17%)
Query: 233 QGYAAGPYHHHQPMPGYLDMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCP 292
Q AGP+ P G+ D+P G +R E ++S P L G G
Sbjct: 234 QQLGAGPFPAQPPGRGF-DLPPALASGSADAARKERA---LDSPPPPTLACGSGGGSQGD 289
Query: 293 KEQAQPPHLWKSTLPDVVSHPSDAS---------------------SYRRGRKKRVPYTK 331
+E H S ++ PS++S + + GRKKR PYTK
Sbjct: 290 EEA----HASSSAAEELSPAPSESSKASPEKDSLGNSKGENAANWLTAKSGRKKRCPYTK 345
Query: 332 VQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKKV 380
Q ELE+E+ N ++T+++R IS + +L++RQV IWFQNRR+K KK+
Sbjct: 346 HQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKM 394
>gi|23510366 homeobox D10 [Homo sapiens]
Length = 340
Score = 75.5 bits (184), Expect = 8e-14
Identities = 34/61 (55%), Positives = 47/61 (77%)
Query: 320 RRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKK 379
+ GRKKR PYTK Q ELE+E+ N ++T+++R IS + NL++RQV IWFQNRR+K KK
Sbjct: 264 KSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKK 323
Query: 380 V 380
+
Sbjct: 324 M 324
>gi|23097236 homeobox A9 [Homo sapiens]
Length = 272
Score = 74.7 bits (182), Expect = 1e-13
Identities = 34/61 (55%), Positives = 45/61 (73%)
Query: 320 RRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKK 379
R RKKR PYTK Q ELE+E+ N ++T+D+R ++ NL+ERQV IWFQNRR+K KK
Sbjct: 204 RSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKK 263
Query: 380 V 380
+
Sbjct: 264 I 264
>gi|126090909 engrailed homeobox 1 [Homo sapiens]
Length = 392
Score = 74.3 bits (181), Expect = 2e-13
Identities = 93/380 (24%), Positives = 139/380 (36%), Gaps = 73/380 (19%)
Query: 37 GAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCR-------N 89
GAAAAA + + G G + + + G+ + A + A C +
Sbjct: 17 GAAAAATPGGLSLSLSPGASG---SSGSGSDGDSVPVSPQPAPPSPPAAPCLPPLAHHPH 73
Query: 90 LMAHPAPLAPG--AASAYSSAPG------------------------EAPPSAAAAAAAA 123
L HP P P AA A+ P + PP AAAA
Sbjct: 74 LPPHPPPPPPQHLAAPAHQPQPAAQLHRTTNFFIDNILRPDFGCKKEQPPPQLLVAAAAR 133
Query: 124 AAAAAAAAAASSSG----GPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYY 179
A G G P P G A S A + P G+G
Sbjct: 134 GGAGGGGRVERDRGQTAAGRDPVHPLGTRAPGAASLLCAPDANCGPPDGSQPAAAGAG-- 191
Query: 180 PCARMGPHPNAIKSCAQPASAAAAAAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGP 239
A +P A + A A AAAAAA A K DT G + G A P
Sbjct: 192 --ASKAGNPAAAAAAAAAAVAAAAAAAAAKPSDTGGGGSG--------------GGAGSP 235
Query: 240 YHHHQPMPGYLDMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPP 299
P + + P + G + P+ + +S QP W +YC + +P
Sbjct: 236 GAQGTKYPEHGN----PAILLMGSANGGPV-VKTDSQQPLV----WPAWVYCTRYSDRP- 285
Query: 300 HLWKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATT 359
S+ P + + ++ R +T QL+ L+ E+ N++IT+ +R+ ++
Sbjct: 286 ----SSGPRTRKLKKKKNE-KEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQEL 340
Query: 360 NLSERQVTIWFQNRRVKEKK 379
+L+E Q+ IWFQN+R K KK
Sbjct: 341 SLNESQIKIWFQNKRAKIKK 360
Score = 42.0 bits (97), Expect = 0.001
Identities = 42/130 (32%), Positives = 48/130 (36%), Gaps = 20/130 (15%)
Query: 23 GGGLVADELNKNMEGA---------AAAAAAAAAAAAAGAGGGGFPHPAAAAAG----GN 69
GGG V + + G A AA+ A A G PAAA AG GN
Sbjct: 138 GGGRVERDRGQTAAGRDPVHPLGTRAPGAASLLCAPDANCGPPDGSQPAAAGAGASKAGN 197
Query: 70 FSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAA 129
+ AAAAAAAA AAA A A P S G P A A
Sbjct: 198 PAAAAAAAAAAVAAA-------AAAAAAKPSDTGGGGSGGGAGSPGAQGTKYPEHGNPAI 250
Query: 130 AAAASSSGGP 139
S++GGP
Sbjct: 251 LLMGSANGGP 260
Score = 31.2 bits (69), Expect = 1.7
Identities = 29/94 (30%), Positives = 38/94 (40%), Gaps = 6/94 (6%)
Query: 114 PSAAAAAAAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAA--LPY 171
P + +A AAAAA S S PG +G +G+ + P S S PAA LP
Sbjct: 8 PKSQRDSALGAAAAATPGGLSLSLSPGASGSSGSGSDGDSVPVSPQPAPPSPPAAPCLP- 66
Query: 172 GYFGSGYYPCARMGPHPNAIKSCAQPASAAAAAA 205
++P P P + A PA AA
Sbjct: 67 ---PLAHHPHLPPHPPPPPPQHLAAPAHQPQPAA 97
>gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]
Length = 283
Score = 73.9 bits (180), Expect = 2e-13
Identities = 47/148 (31%), Positives = 71/148 (47%), Gaps = 18/148 (12%)
Query: 236 AAGPYHHHQPMPGYLDMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQ 295
A HHH +P L +P H P G E +P L Q+ P +
Sbjct: 78 AVAHLHHH--LPAQLALP------------HPPAGPFPEGAEPGVLEEPNRVQLPFPWMK 123
Query: 296 AQPPHLWKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRI 355
+ H WK + + A+ ++ R YT+ QL ELE+E+ NK+I++ +R +
Sbjct: 124 STKAHAWKGQW----AGGAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVEL 179
Query: 356 SATTNLSERQVTIWFQNRRVKEKKVINK 383
+ NL+ER + IWFQNRR+K KK +K
Sbjct: 180 AVMLNLTERHIKIWFQNRRMKWKKEEDK 207
>gi|24497551 homeobox A10 isoform b [Homo sapiens]
Length = 94
Score = 73.6 bits (179), Expect = 3e-13
Identities = 33/61 (54%), Positives = 47/61 (77%)
Query: 320 RRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKK 379
+ GRKKR PYTK Q ELE+E+ N ++T+++R IS + +L++RQV IWFQNRR+K KK
Sbjct: 18 KSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKK 77
Query: 380 V 380
+
Sbjct: 78 M 78
>gi|24497538 homeobox C4 [Homo sapiens]
Length = 264
Score = 72.8 bits (177), Expect = 5e-13
Identities = 66/213 (30%), Positives = 89/213 (41%), Gaps = 54/213 (25%)
Query: 210 YMDTAGPAAEEFSSRA----KEFAFYHQGYAAGPYHHHQ-------PMPGYLDMPV-VPG 257
Y+D P EE+S + +Y + +G HHHQ P P Y +
Sbjct: 12 YIDPKFPPCEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELYPPPPPRPSYPERQYSCTS 71
Query: 258 LGGPGESR---------HEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLPD 308
L GPG SR H P E Q P +G P + P PD
Sbjct: 72 LQGPGNSRGHGPAQAGHHHP-----EKSQSLCEPAPLSGASASP---SPAPPACSQPAPD 123
Query: 309 VVSHPSDASS--------------------YRRGRKKR--VPYTKVQLKELEREYATNKF 346
HPS A+S Y G KR YT+ Q+ ELE+E+ N++
Sbjct: 124 ---HPSSAASKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRY 180
Query: 347 ITKDKRRRISATTNLSERQVTIWFQNRRVKEKK 379
+T+ +R I+ + LSERQ+ IWFQNRR+K KK
Sbjct: 181 LTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKK 213
>gi|24497540 homeobox C4 [Homo sapiens]
Length = 264
Score = 72.8 bits (177), Expect = 5e-13
Identities = 66/213 (30%), Positives = 89/213 (41%), Gaps = 54/213 (25%)
Query: 210 YMDTAGPAAEEFSSRA----KEFAFYHQGYAAGPYHHHQ-------PMPGYLDMPV-VPG 257
Y+D P EE+S + +Y + +G HHHQ P P Y +
Sbjct: 12 YIDPKFPPCEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELYPPPPPRPSYPERQYSCTS 71
Query: 258 LGGPGESR---------HEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLPD 308
L GPG SR H P E Q P +G P + P PD
Sbjct: 72 LQGPGNSRGHGPAQAGHHHP-----EKSQSLCEPAPLSGASASP---SPAPPACSQPAPD 123
Query: 309 VVSHPSDASS--------------------YRRGRKKR--VPYTKVQLKELEREYATNKF 346
HPS A+S Y G KR YT+ Q+ ELE+E+ N++
Sbjct: 124 ---HPSSAASKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRY 180
Query: 347 ITKDKRRRISATTNLSERQVTIWFQNRRVKEKK 379
+T+ +R I+ + LSERQ+ IWFQNRR+K KK
Sbjct: 181 LTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKK 213
>gi|33457326 GS homeobox 1 [Homo sapiens]
Length = 264
Score = 72.0 bits (175), Expect = 8e-13
Identities = 51/146 (34%), Positives = 76/146 (52%), Gaps = 18/146 (12%)
Query: 243 HQPMPGYLDMPVVPGLGGPGESR--HEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPH 300
H P PG +P++ P S+ H PLG + P G + P A
Sbjct: 68 HGP-PGPPALPLLKASFPPFGSQYCHAPLGRQHSAVSP--------GVAHGPAAAAAAAA 118
Query: 301 LWKST--LPD-----VVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRR 353
L++++ LPD +S S ++ ++ R +T QL ELERE+A+N ++++ +R
Sbjct: 119 LYQTSYPLPDPRQFHCISVDSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRI 178
Query: 354 RISATTNLSERQVTIWFQNRRVKEKK 379
I+ NLSE+QV IWFQNRRVK KK
Sbjct: 179 EIATYLNLSEKQVKIWFQNRRVKHKK 204
>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
[Homo sapiens]
Length = 2191
Score = 71.6 bits (174), Expect = 1e-12
Identities = 60/168 (35%), Positives = 75/168 (44%), Gaps = 35/168 (20%)
Query: 37 GAAAAAAAAAAAAAAGAGGGGFPHPAAA------------------AAGGNFSVAAAAAA 78
GA AAAAAAAAAAA G GGGG+ +A GG S++ AAA
Sbjct: 279 GAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAG 338
Query: 79 AAA------AAANQ--------CRNLMAHPAPLAPGAASAYS--SAPGEAPPSAAAAAAA 122
+AA A NQ L+ P+P+ +Y S+P PP + +
Sbjct: 339 SAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQ 398
Query: 123 AAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALP 170
AAAA AAA ++ G G GA+ A SP AAAQ S PA P
Sbjct: 399 AAAAGAAAGGQQAAAGMGLGKDMGAQYA-AASPAWAAAQQRSHPAMSP 445
Score = 48.5 bits (114), Expect = 1e-05
Identities = 58/210 (27%), Positives = 77/210 (36%), Gaps = 35/210 (16%)
Query: 13 EPTVMFLYDNGGGLVADELNKNMEGAAAAAAAAAAAAAAG---------AGGGGFPHPA- 62
+P V GG E N N G+AA A+ A + G G H A
Sbjct: 154 QPPVAVPGGGGGPAAVPEFN-NYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSAS 212
Query: 63 AAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAASAY------SSAPGEAPPSA 116
AAAAG S+ + +QC + + P A G S G +
Sbjct: 213 AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAG 272
Query: 117 AAAAAAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGS 176
A A A A AAAAAAAA+++GG G G G+ A S+ Q G
Sbjct: 273 AGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAG--YGVLSSPRQQGGG----------- 319
Query: 177 GYYPCARMGPHPNAIKSCAQPASAAAAAAF 206
MGP S ++ A+ +AA F
Sbjct: 320 -----MMMGPGGGGAASLSKAAAGSAAGGF 344
Score = 47.4 bits (111), Expect = 2e-05
Identities = 78/301 (25%), Positives = 102/301 (33%), Gaps = 48/301 (15%)
Query: 22 NGGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAA 81
+GGG GA A AAAAAAAAAA GGGG G + ++A +
Sbjct: 262 SGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGG----------GGYGGSSAGYGVLS 311
Query: 82 AAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSG---- 137
+ Q +M + PG A S + AAA +AA A SG
Sbjct: 312 SPRQQGGGMM-----MGPGGGGAASLS------KAAAGSAAGGFQRFAGQNQHPSGATPT 360
Query: 138 ------GPGPA----GPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGPH 187
P P G + E + +P +Q S AA G +G
Sbjct: 361 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD 420
Query: 188 PNAIKSCAQPASAAA-AAAFADKYMDTAGP--AAEEFSSRAKEFAFYHQGYAAGPYHHHQ 244
A + A PA AAA + T GP + S Q Y G H Q
Sbjct: 421 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ 480
Query: 245 PMPGYLDMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHLWKS 304
P P G GP + P+G+ + P G Y P++Q WK
Sbjct: 481 PQQ---SSPYPGGSYGPPGPQRYPIGIQGRT------PGAMAGMQY-PQQQDSGDATWKE 530
Query: 305 T 305
T
Sbjct: 531 T 531
Score = 31.6 bits (70), Expect = 1.3
Identities = 38/129 (29%), Positives = 51/129 (39%), Gaps = 22/129 (17%)
Query: 52 GAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRN------------LMAHPAPLAP 99
G G G P P N AAAA AAAN ++ LMA +P +
Sbjct: 869 GGPGMGPPMPTV-----NRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQ 923
Query: 100 GAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSGG----PGPAGPAGAEAAKQCSP 155
++ S +APP + A A ++AA+ A S G P P G E P
Sbjct: 924 PMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTP-QP 982
Query: 156 CSAAAQSSS 164
S + +SSS
Sbjct: 983 ESKSKKSSS 991
Score = 29.6 bits (65), Expect = 4.8
Identities = 28/84 (33%), Positives = 36/84 (42%), Gaps = 14/84 (16%)
Query: 39 AAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLA 98
AAAA AAA +A + G FP G N S A+++ + N +LM AP
Sbjct: 887 AAAAVMQAAANSAQSRQGSFP-------GMNQSGLMASSSPYSQPMNNSSSLMNTQAP-- 937
Query: 99 PGAASAYSSAPGEAPPSAAAAAAA 122
YS AP SAA+ A
Sbjct: 938 -----PYSMAPAMVNSSAASVGLA 956
>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
[Homo sapiens]
Length = 2231
Score = 71.6 bits (174), Expect = 1e-12
Identities = 60/168 (35%), Positives = 75/168 (44%), Gaps = 35/168 (20%)
Query: 37 GAAAAAAAAAAAAAAGAGGGGFPHPAAA------------------AAGGNFSVAAAAAA 78
GA AAAAAAAAAAA G GGGG+ +A GG S++ AAA
Sbjct: 279 GAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAG 338
Query: 79 AAA------AAANQ--------CRNLMAHPAPLAPGAASAYS--SAPGEAPPSAAAAAAA 122
+AA A NQ L+ P+P+ +Y S+P PP + +
Sbjct: 339 SAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQ 398
Query: 123 AAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALP 170
AAAA AAA ++ G G GA+ A SP AAAQ S PA P
Sbjct: 399 AAAAGAAAGGQQAAAGMGLGKDMGAQYA-AASPAWAAAQQRSHPAMSP 445
Score = 48.5 bits (114), Expect = 1e-05
Identities = 58/210 (27%), Positives = 77/210 (36%), Gaps = 35/210 (16%)
Query: 13 EPTVMFLYDNGGGLVADELNKNMEGAAAAAAAAAAAAAAG---------AGGGGFPHPA- 62
+P V GG E N N G+AA A+ A + G G H A
Sbjct: 154 QPPVAVPGGGGGPAAVPEFN-NYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSAS 212
Query: 63 AAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAASAY------SSAPGEAPPSA 116
AAAAG S+ + +QC + + P A G S G +
Sbjct: 213 AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAG 272
Query: 117 AAAAAAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGS 176
A A A A AAAAAAAA+++GG G G G+ A S+ Q G
Sbjct: 273 AGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAG--YGVLSSPRQQGGG----------- 319
Query: 177 GYYPCARMGPHPNAIKSCAQPASAAAAAAF 206
MGP S ++ A+ +AA F
Sbjct: 320 -----MMMGPGGGGAASLSKAAAGSAAGGF 344
Score = 47.4 bits (111), Expect = 2e-05
Identities = 82/317 (25%), Positives = 107/317 (33%), Gaps = 63/317 (19%)
Query: 22 NGGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAA 81
+GGG GA A AAAAAAAAAA GGGG G + ++A +
Sbjct: 262 SGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGG----------GGYGGSSAGYGVLS 311
Query: 82 AAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSG---- 137
+ Q +M + PG A S + AAA +AA A SG
Sbjct: 312 SPRQQGGGMM-----MGPGGGGAASLS------KAAAGSAAGGFQRFAGQNQHPSGATPT 360
Query: 138 ------GPGPA----GPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGPH 187
P P G + E + +P +Q S AA G +G
Sbjct: 361 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD 420
Query: 188 PNAIKSCAQPASAAA-AAAFADKYMDTAGP--AAEEFSSRAKEFAFYHQGYAAGPYHHHQ 244
A + A PA AAA + T GP + S Q Y G H Q
Sbjct: 421 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ 480
Query: 245 PMPGYLDMPVVPGLGGPGESRHEPLGL-------------PMESYQPWALPNGWNGQMYC 291
P P G GP + P+G+ P + P G +G YC
Sbjct: 481 PQQ---SSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSG--YC 535
Query: 292 PK-------EQAQPPHL 301
+ +Q QPPHL
Sbjct: 536 QQGQQPYYSQQPQPPHL 552
Score = 34.3 bits (77), Expect = 0.20
Identities = 47/170 (27%), Positives = 55/170 (32%), Gaps = 32/170 (18%)
Query: 48 AAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPA--PLAPGAASAY 105
AAAAGA GG A G + AAA+ A AAA Q +HPA P PG
Sbjct: 399 AAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQ----RSHPAMSPGTPGPTMGR 454
Query: 106 SSAPGEAPPSAAAAAAAAAAAAAAAAAASSS----GGPGPAGP---------------AG 146
S P + + SS G GP GP AG
Sbjct: 455 SQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAG 514
Query: 147 AEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGPHPNAIKSCAQ 196
+ +Q P Q S GY G P P P + AQ
Sbjct: 515 MQYPQQQMPPQYGQQGVS-------GYCQQGQQPYYSQQPQPPHLPPQAQ 557
Score = 31.6 bits (70), Expect = 1.3
Identities = 45/188 (23%), Positives = 70/188 (37%), Gaps = 28/188 (14%)
Query: 52 GAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRN------------LMAHPAPLAP 99
G G G P P N AAAA AAAN ++ LMA +P +
Sbjct: 856 GGPGMGPPMPTV-----NRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQ 910
Query: 100 GAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSGGPGPAG-PAGAEAAKQCSPCSA 158
++ S +APP + A A ++AA+ A S G P A+ ++ +P
Sbjct: 911 PMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPE 970
Query: 159 AAQSSSGPAALPYGYFGSGYYPCARMGPHPNAIKSCAQPASAAAAAAFADKYMDTAGPAA 218
+ S Y G P P P+ + P+SA+ ++ D+ + P
Sbjct: 971 SKSKDS------YSSQGISQPPTPGNLPVPSPM----SPSSASISSFHGDESDSISSPGW 1020
Query: 219 EEFSSRAK 226
+ S K
Sbjct: 1021 PKTPSSPK 1028
Score = 29.6 bits (65), Expect = 4.8
Identities = 28/84 (33%), Positives = 36/84 (42%), Gaps = 14/84 (16%)
Query: 39 AAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLA 98
AAAA AAA +A + G FP G N S A+++ + N +LM AP
Sbjct: 874 AAAAVMQAAANSAQSRQGSFP-------GMNQSGLMASSSPYSQPMNNSSSLMNTQAP-- 924
Query: 99 PGAASAYSSAPGEAPPSAAAAAAA 122
YS AP SAA+ A
Sbjct: 925 -----PYSMAPAMVNSSAASVGLA 943
>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
[Homo sapiens]
Length = 2178
Score = 71.6 bits (174), Expect = 1e-12
Identities = 60/168 (35%), Positives = 75/168 (44%), Gaps = 35/168 (20%)
Query: 37 GAAAAAAAAAAAAAAGAGGGGFPHPAAA------------------AAGGNFSVAAAAAA 78
GA AAAAAAAAAAA G GGGG+ +A GG S++ AAA
Sbjct: 279 GAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAG 338
Query: 79 AAA------AAANQ--------CRNLMAHPAPLAPGAASAYS--SAPGEAPPSAAAAAAA 122
+AA A NQ L+ P+P+ +Y S+P PP + +
Sbjct: 339 SAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQ 398
Query: 123 AAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALP 170
AAAA AAA ++ G G GA+ A SP AAAQ S PA P
Sbjct: 399 AAAAGAAAGGQQAAAGMGLGKDMGAQYA-AASPAWAAAQQRSHPAMSP 445
Score = 48.5 bits (114), Expect = 1e-05
Identities = 58/210 (27%), Positives = 77/210 (36%), Gaps = 35/210 (16%)
Query: 13 EPTVMFLYDNGGGLVADELNKNMEGAAAAAAAAAAAAAAG---------AGGGGFPHPA- 62
+P V GG E N N G+AA A+ A + G G H A
Sbjct: 154 QPPVAVPGGGGGPAAVPEFN-NYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSAS 212
Query: 63 AAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAASAY------SSAPGEAPPSA 116
AAAAG S+ + +QC + + P A G S G +
Sbjct: 213 AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAG 272
Query: 117 AAAAAAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGS 176
A A A A AAAAAAAA+++GG G G G+ A S+ Q G
Sbjct: 273 AGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAG--YGVLSSPRQQGGG----------- 319
Query: 177 GYYPCARMGPHPNAIKSCAQPASAAAAAAF 206
MGP S ++ A+ +AA F
Sbjct: 320 -----MMMGPGGGGAASLSKAAAGSAAGGF 344
Score = 47.4 bits (111), Expect = 2e-05
Identities = 82/317 (25%), Positives = 107/317 (33%), Gaps = 63/317 (19%)
Query: 22 NGGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAA 81
+GGG GA A AAAAAAAAAA GGGG G + ++A +
Sbjct: 262 SGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGG----------GGYGGSSAGYGVLS 311
Query: 82 AAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSG---- 137
+ Q +M + PG A S + AAA +AA A SG
Sbjct: 312 SPRQQGGGMM-----MGPGGGGAASLS------KAAAGSAAGGFQRFAGQNQHPSGATPT 360
Query: 138 ------GPGPA----GPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGPH 187
P P G + E + +P +Q S AA G +G
Sbjct: 361 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD 420
Query: 188 PNAIKSCAQPASAAA-AAAFADKYMDTAGP--AAEEFSSRAKEFAFYHQGYAAGPYHHHQ 244
A + A PA AAA + T GP + S Q Y G H Q
Sbjct: 421 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ 480
Query: 245 PMPGYLDMPVVPGLGGPGESRHEPLGL-------------PMESYQPWALPNGWNGQMYC 291
P P G GP + P+G+ P + P G +G YC
Sbjct: 481 PQQ---SSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSG--YC 535
Query: 292 PK-------EQAQPPHL 301
+ +Q QPPHL
Sbjct: 536 QQGQQPYYSQQPQPPHL 552
Score = 34.3 bits (77), Expect = 0.20
Identities = 47/170 (27%), Positives = 55/170 (32%), Gaps = 32/170 (18%)
Query: 48 AAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPA--PLAPGAASAY 105
AAAAGA GG A G + AAA+ A AAA Q +HPA P PG
Sbjct: 399 AAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQ----RSHPAMSPGTPGPTMGR 454
Query: 106 SSAPGEAPPSAAAAAAAAAAAAAAAAAASSS----GGPGPAGP---------------AG 146
S P + + SS G GP GP AG
Sbjct: 455 SQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAG 514
Query: 147 AEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGPHPNAIKSCAQ 196
+ +Q P Q S GY G P P P + AQ
Sbjct: 515 MQYPQQQMPPQYGQQGVS-------GYCQQGQQPYYSQQPQPPHLPPQAQ 557
Score = 31.6 bits (70), Expect = 1.3
Identities = 38/129 (29%), Positives = 51/129 (39%), Gaps = 22/129 (17%)
Query: 52 GAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRN------------LMAHPAPLAP 99
G G G P P N AAAA AAAN ++ LMA +P +
Sbjct: 856 GGPGMGPPMPTV-----NRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQ 910
Query: 100 GAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSGG----PGPAGPAGAEAAKQCSP 155
++ S +APP + A A ++AA+ A S G P P G E P
Sbjct: 911 PMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTP-QP 969
Query: 156 CSAAAQSSS 164
S + +SSS
Sbjct: 970 ESKSKKSSS 978
Score = 29.6 bits (65), Expect = 4.8
Identities = 28/84 (33%), Positives = 36/84 (42%), Gaps = 14/84 (16%)
Query: 39 AAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLA 98
AAAA AAA +A + G FP G N S A+++ + N +LM AP
Sbjct: 874 AAAAVMQAAANSAQSRQGSFP-------GMNQSGLMASSSPYSQPMNNSSSLMNTQAP-- 924
Query: 99 PGAASAYSSAPGEAPPSAAAAAAA 122
YS AP SAA+ A
Sbjct: 925 -----PYSMAPAMVNSSAASVGLA 943
>gi|121114296 caudal type homeobox 1 [Homo sapiens]
Length = 265
Score = 70.9 bits (172), Expect = 2e-12
Identities = 75/247 (30%), Positives = 94/247 (38%), Gaps = 48/247 (19%)
Query: 139 PGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGPHPNAIKSCAQPA 198
PGPA PA Q A P P Y Y P P PA
Sbjct: 15 PGPARPASLGLGPQ-------AYGPPAPPPAPPQYPDFSSYSHVEPAPAPPTAWGAPFPA 67
Query: 199 SAAA-AAAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPYHHHQPMPGYLDMPVVPG 257
AAA+ GPAA S + F P P + +P PG
Sbjct: 68 PKDDWAAAYGP------GPAAPAASPASLAFG---------------PPPDFSPVPAPPG 106
Query: 258 LGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLPDVVSHPSDAS 317
GPG +PLG P G P Q P+ W V + S
Sbjct: 107 -PGPGLLA-QPLGGP--------------GTPSSPGAQRPTPYEWMRR--SVAAGGGGGS 148
Query: 318 SYRRGRKK-RVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVK 376
R + K RV YT Q ELE+E+ +++IT ++ ++A L+ERQV IWFQNRR K
Sbjct: 149 GKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAK 208
Query: 377 EKKVINK 383
E+KV K
Sbjct: 209 ERKVNKK 215
Score = 33.5 bits (75), Expect = 0.33
Identities = 34/97 (35%), Positives = 40/97 (41%), Gaps = 12/97 (12%)
Query: 94 PAPLAPGAASAYSSA-PGEAPPSAAAAAAAAAAAAAAAAAASSSGGPGPAGPAGAEAA-- 150
PAP S+YS P APP+A A A AAA GPGPA PA + A+
Sbjct: 37 PAPPQYPDFSSYSHVEPAPAPPTAWGAPFPAPKDDWAAAY-----GPGPAAPAASPASLA 91
Query: 151 ----KQCSPCSAAAQSSSGPAALPYGYFGSGYYPCAR 183
SP A G A P G G+ P A+
Sbjct: 92 FGPPPDFSPVPAPPGPGPGLLAQPLGGPGTPSSPGAQ 128
Score = 31.2 bits (69), Expect = 1.7
Identities = 29/85 (34%), Positives = 31/85 (36%), Gaps = 9/85 (10%)
Query: 94 PAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSGGPGP-----AGPAGAE 148
PAP P A A P AP AAA AA AA+ AS + GP P P G
Sbjct: 53 PAPAPPTAWGA----PFPAPKDDWAAAYGPGPAAPAASPASLAFGPPPDFSPVPAPPGPG 108
Query: 149 AAKQCSPCSAAAQSSSGPAALPYGY 173
P SS A P Y
Sbjct: 109 PGLLAQPLGGPGTPSSPGAQRPTPY 133
Score = 29.3 bits (64), Expect = 6.3
Identities = 29/95 (30%), Positives = 35/95 (36%), Gaps = 5/95 (5%)
Query: 47 AAAAAGAGGGGFPHPA---AAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAAS 103
A A A G FP P AAA G AA AA+ A+ A + PAP PG
Sbjct: 54 APAPPTAWGAPFPAPKDDWAAAYGPG--PAAPAASPASLAFGPPPDFSPVPAPPGPGPGL 111
Query: 104 AYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSGG 138
G PS+ A + A+ GG
Sbjct: 112 LAQPLGGPGTPSSPGAQRPTPYEWMRRSVAAGGGG 146
>gi|169636435 caudal type homeobox 2 [Homo sapiens]
Length = 313
Score = 69.7 bits (169), Expect = 4e-12
Identities = 81/268 (30%), Positives = 104/268 (38%), Gaps = 71/268 (26%)
Query: 124 AAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCAR 183
AAAAAAAA S+ PGP+ PA A P +GY P
Sbjct: 46 AAAAAAAANLDSAQSPGPSWPAAYGA--------------------PLREDWNGYAP--- 82
Query: 184 MGPHPNAIKSCAQPASAAAAAAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPYHH- 242
+AAAA A A + AA +SS A +H P+HH
Sbjct: 83 -------------GGAAAAANAVAHGLNGGSPAAAMGYSSPADYHPHHH------PHHHP 123
Query: 243 HQPMPGY-----LDMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQ 297
H P L + PG GP + E P M P +Q+
Sbjct: 124 HHPAAAPSCASGLLQTLNPGPPGPAATA------AAEQLSPGGQRRNLCEWMRKPAQQSL 177
Query: 298 PPHLWKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISA 357
+ R K RV YT Q ELE+E+ +++IT ++ ++A
Sbjct: 178 GSQV----------------KTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAA 221
Query: 358 TTNLSERQVTIWFQNRRVKEKKVINKLK 385
T LSERQV IWFQNRR KE+K INK K
Sbjct: 222 TLGLSERQVKIWFQNRRAKERK-INKKK 248
Score = 46.2 bits (108), Expect = 5e-05
Identities = 44/120 (36%), Positives = 57/120 (47%), Gaps = 10/120 (8%)
Query: 39 AAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPL- 97
AAAAAAAA +A + G +P A +++ A AAAAA N +AH
Sbjct: 46 AAAAAAAANLDSAQSPGPSWPAAYGAPLREDWNGYAPGGAAAAA------NAVAHGLNGG 99
Query: 98 APGAASAYSSAPGEAPPSAAAAAAA--AAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSP 155
+P AA YSS P + P AAA + A+ + PGP GPA AA+Q SP
Sbjct: 100 SPAAAMGYSS-PADYHPHHHPHHHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSP 158
>gi|4885127 caudal type homeobox 4 [Homo sapiens]
Length = 284
Score = 69.7 bits (169), Expect = 4e-12
Identities = 67/249 (26%), Positives = 92/249 (36%), Gaps = 34/249 (13%)
Query: 135 SSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGPHPNAIKSC 194
S GG G AG G P S A + PA Y GY M PH ++
Sbjct: 20 SPGGDGTAGTGGTGGGGSPMPASNFA---AAPAFSHY----MGYPHMPSMDPHWPSLGVW 72
Query: 195 AQPASAAAAAAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPYHHHQPMPGYLDMPV 254
P S + + GP++ + + + + Y + P+ G
Sbjct: 73 GSPYSPPR-----EDWSVYPGPSSTMGTVPVNDVTSSPAAFCSTDYSNLGPVGGGTSGSS 127
Query: 255 VPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLPDVVSHPS 314
+PG G G G S P P+ W V
Sbjct: 128 LPGQAG-GSLVPTDAGAAKAS---------------SPSRSRHSPYAWMRKTVQVTGKT- 170
Query: 315 DASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRR 374
R K RV YT Q ELE+E+ N++IT ++ ++ LSERQV IWFQNRR
Sbjct: 171 -----RTKEKYRVVYTDHQRLELEKEFHCNRYITIQRKSELAVNLGLSERQVKIWFQNRR 225
Query: 375 VKEKKVINK 383
KE+K+I K
Sbjct: 226 AKERKMIKK 234
Score = 31.2 bits (69), Expect = 1.7
Identities = 38/141 (26%), Positives = 49/141 (34%), Gaps = 29/141 (20%)
Query: 37 GAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAP 96
G + A G GGGG P PA+ NF AAA A + ++ H
Sbjct: 16 GTLMSPGGDGTAGTGGTGGGGSPMPAS-----NF--AAAPAFSHYMGYPHMPSMDPHWPS 68
Query: 97 LA----------------PGAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSGG-- 138
L PG +S + P S+ AA + + +SG
Sbjct: 69 LGVWGSPYSPPREDWSVYPGPSSTMGTVPVNDVTSSPAAFCSTDYSNLGPVGGGTSGSSL 128
Query: 139 PGPAG----PAGAEAAKQCSP 155
PG AG P A AAK SP
Sbjct: 129 PGQAGGSLVPTDAGAAKASSP 149
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.126 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,045,352
Number of Sequences: 37866
Number of extensions: 1060580
Number of successful extensions: 36553
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1026
Number of HSP's successfully gapped in prelim test: 939
Number of HSP's that attempted gapping in prelim test: 11482
Number of HSP's gapped (non-prelim): 12073
length of query: 388
length of database: 18,247,518
effective HSP length: 104
effective length of query: 284
effective length of database: 14,309,454
effective search space: 4063884936
effective search space used: 4063884936
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.