Search of human proteins with 226443022

Search of human proteins with 226443022

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226443022 GRAM domain containing 3 isoform 4 [Homo sapiens]
         (440 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226443022 GRAM domain containing 3 isoform 4 [Homo sapiens]        879   0.0  
gi|226443028 GRAM domain containing 3 isoform 5 [Homo sapiens]        718   0.0  
gi|226443011 GRAM domain containing 3 isoform 1 [Homo sapiens]        718   0.0  
gi|226443007 GRAM domain containing 3 isoform 2 [Homo sapiens]        718   0.0  
gi|226443017 GRAM domain containing 3 isoform 3 [Homo sapiens]        647   0.0  
gi|60593095 GRAM domain containing 2 [Homo sapiens]                   140   2e-33
gi|209969686 GRAM domain containing 1A isoform 2 [Homo sapiens]       105   6e-23
gi|92110010 GRAM domain containing 1A isoform 1 [Homo sapiens]        104   1e-22
gi|144227752 GRAM domain containing 1B [Homo sapiens]                  99   6e-21
gi|187936935 GRAM domain containing 1C [Homo sapiens]                  97   2e-20
gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Ho...    62   8e-10
gi|156231067 TBC1 domain family, member 8 [Homo sapiens]               54   2e-07
gi|45597177 TBC1 domain family, member 9B (with GRAM domain) iso...    47   3e-05
gi|45597175 TBC1 domain family, member 9B (with GRAM domain) iso...    47   3e-05
gi|38570103 TBC1 domain family, member 8B (with GRAM domain) iso...    44   2e-04
gi|38570101 TBC1 domain family, member 8B (with GRAM domain) iso...    44   2e-04
gi|67763814 death-inducing-protein [Homo sapiens]                      38   0.021
gi|61743940 G-protein coupled receptor 110 isoform 1 [Homo sapiens]    33   0.67 
gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1 [...    32   1.1  
gi|71143141 cyclic nucleotide gated channel alpha 1 isoform 2 [H...    32   1.1  
gi|39995071 exonuclease 1 isoform b [Homo sapiens]                     32   1.5  
gi|39995069 exonuclease 1 isoform a [Homo sapiens]                     32   1.5  
gi|18491016 exonuclease 1 isoform b [Homo sapiens]                     32   1.5  
gi|68989256 ras inhibitor RIN1 [Homo sapiens]                          31   2.0  
gi|242117946 hypothetical protein LOC57579 isoform c [Homo sapiens]    31   2.6  
gi|38788260 bromodomain PHD finger transcription factor isoform ...    31   2.6  
gi|38788274 bromodomain PHD finger transcription factor isoform ...    31   2.6  
gi|55741653 hypothetical protein LOC57691 [Homo sapiens]               31   2.6  
gi|48255931 hepatoma-derived growth factor-related protein 2 iso...    31   2.6  
gi|14249158 hepatoma-derived growth factor-related protein 2 iso...    31   2.6  

>gi|226443022 GRAM domain containing 3 isoform 4 [Homo sapiens]
          Length = 440

 Score =  879 bits (2272), Expect = 0.0
 Identities = 440/440 (100%), Positives = 440/440 (100%)

Query: 1   MWKTQSLRKCSGRGRANLAQPTQRLRMVWRRKRKPAGRQQPNPLPHLWRRTPQTRRKSLA 60
           MWKTQSLRKCSGRGRANLAQPTQRLRMVWRRKRKPAGRQQPNPLPHLWRRTPQTRRKSLA
Sbjct: 1   MWKTQSLRKCSGRGRANLAQPTQRLRMVWRRKRKPAGRQQPNPLPHLWRRTPQTRRKSLA 60

Query: 61  YAHIFSPNLCFIQDQESKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHF 120
           YAHIFSPNLCFIQDQESKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHF
Sbjct: 61  YAHIFSPNLCFIQDQESKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHF 120

Query: 121 HKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTL 180
           HKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTL
Sbjct: 121 HKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTL 180

Query: 181 IKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAE 240
           IKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAE
Sbjct: 181 IKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAE 240

Query: 241 NSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTV 300
           NSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTV
Sbjct: 241 NSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTV 300

Query: 301 LNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAI 360
           LNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAI
Sbjct: 301 LNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAI 360

Query: 361 VVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTA 420
           VVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTA
Sbjct: 361 VVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTA 420

Query: 421 NIVKLEKIQNNLQKLLENGD 440
           NIVKLEKIQNNLQKLLENGD
Sbjct: 421 NIVKLEKIQNNLQKLLENGD 440


>gi|226443028 GRAM domain containing 3 isoform 5 [Homo sapiens]
          Length = 416

 Score =  718 bits (1854), Expect = 0.0
 Identities = 364/364 (100%), Positives = 364/364 (100%)

Query: 77  SKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQS 136
           SKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQS
Sbjct: 53  SKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQS 112

Query: 137 FTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALII 196
           FTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALII
Sbjct: 113 FTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALII 172

Query: 197 ATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFN 256
           ATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFN
Sbjct: 173 ATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFN 232

Query: 257 DEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAH 316
           DEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAH
Sbjct: 233 DEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAH 292

Query: 317 VNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRI 376
           VNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRI
Sbjct: 293 VNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRI 352

Query: 377 NTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLL 436
           NTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLL
Sbjct: 353 NTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLL 412

Query: 437 ENGD 440
           ENGD
Sbjct: 413 ENGD 416


>gi|226443011 GRAM domain containing 3 isoform 1 [Homo sapiens]
          Length = 447

 Score =  718 bits (1854), Expect = 0.0
 Identities = 364/364 (100%), Positives = 364/364 (100%)

Query: 77  SKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQS 136
           SKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQS
Sbjct: 84  SKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQS 143

Query: 137 FTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALII 196
           FTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALII
Sbjct: 144 FTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALII 203

Query: 197 ATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFN 256
           ATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFN
Sbjct: 204 ATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFN 263

Query: 257 DEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAH 316
           DEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAH
Sbjct: 264 DEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAH 323

Query: 317 VNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRI 376
           VNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRI
Sbjct: 324 VNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRI 383

Query: 377 NTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLL 436
           NTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLL
Sbjct: 384 NTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLL 443

Query: 437 ENGD 440
           ENGD
Sbjct: 444 ENGD 447


>gi|226443007 GRAM domain containing 3 isoform 2 [Homo sapiens]
          Length = 432

 Score =  718 bits (1854), Expect = 0.0
 Identities = 364/364 (100%), Positives = 364/364 (100%)

Query: 77  SKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQS 136
           SKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQS
Sbjct: 69  SKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQS 128

Query: 137 FTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALII 196
           FTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALII
Sbjct: 129 FTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALII 188

Query: 197 ATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFN 256
           ATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFN
Sbjct: 189 ATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFN 248

Query: 257 DEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAH 316
           DEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAH
Sbjct: 249 DEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAH 308

Query: 317 VNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRI 376
           VNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRI
Sbjct: 309 VNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRI 368

Query: 377 NTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLL 436
           NTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLL
Sbjct: 369 NTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLL 428

Query: 437 ENGD 440
           ENGD
Sbjct: 429 ENGD 432


>gi|226443017 GRAM domain containing 3 isoform 3 [Homo sapiens]
          Length = 328

 Score =  647 bits (1669), Expect = 0.0
 Identities = 327/327 (100%), Positives = 327/327 (100%)

Query: 114 YKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISI 173
           YKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISI
Sbjct: 2   YKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISI 61

Query: 174 PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNS 233
           PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNS
Sbjct: 62  PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNS 121

Query: 234 PNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFH 293
           PNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFH
Sbjct: 122 PNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFH 181

Query: 294 ATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHH 353
           ATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHH
Sbjct: 182 ATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHH 241

Query: 354 ILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEV 413
           ILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEV
Sbjct: 242 ILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEV 301

Query: 414 LCQELTANIVKLEKIQNNLQKLLENGD 440
           LCQELTANIVKLEKIQNNLQKLLENGD
Sbjct: 302 LCQELTANIVKLEKIQNNLQKLLENGD 328


>gi|60593095 GRAM domain containing 2 [Homo sapiens]
          Length = 354

 Score =  140 bits (354), Expect = 2e-33
 Identities = 99/281 (35%), Positives = 140/281 (49%), Gaps = 20/281 (7%)

Query: 115 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIP 174
           K N  +HKLF  VP EE + +  +CALQ++ L QG+L++S NW+CFH+ +FGKD K+ IP
Sbjct: 69  KYNQQYHKLFKDVPLEEVVLKVCSCALQRDFLLQGRLYISPNWLCFHASLFGKDIKVVIP 128

Query: 175 AFSVTLIKKTKTALLVPNALIIATVT-DRYIFVSLLSRDSTYKLLKSVCGHLENTSVGN- 232
             SV +IKK K A L+PN L I T T  +YIFVSLLSRDS Y LL+ VC HL+ +S  + 
Sbjct: 129 VVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRDSVYDLLRRVCTHLQPSSKKSL 188

Query: 233 -----SPNPSS-----AENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQ 282
                S  P S      E  +R   PSS  L   D        +     D         +
Sbjct: 189 SVREFSGEPESLEVLIPEMKWRKVCPSSRSLSLPDNIP----CIPPSSVDSTDSFFPSRK 244

Query: 283 TPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHK 342
            P SE SR   A+E+            P       N  P  K        L E      +
Sbjct: 245 PPMSEKSRAQVASENGGRWAWPMPGWGPACPKKMPNCSPTAKNAVYEEDELEEEPRSTGE 304

Query: 343 VKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQL 383
           ++       + +L  + +++C L++S+ Y+ +RI+ LE+QL
Sbjct: 305 LRLWD----YRLLKVFFVLICFLVMSSSYLAFRISRLEQQL 341


>gi|209969686 GRAM domain containing 1A isoform 2 [Homo sapiens]
          Length = 713

 Score =  105 bits (263), Expect = 6e-23
 Identities = 64/179 (35%), Positives = 93/179 (51%), Gaps = 5/179 (2%)

Query: 45  PHLWRRTPQTRRKSLAYAHIFSPNLCFIQDQESKSSFDGASLASDKNDC----KTESKND 100
           PH  R TP +         +  P+    + +       G+  +S+K        T+S   
Sbjct: 6   PHSGRSTPSSSPSLRKRLQLLPPSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPSTQSLGS 65

Query: 101 PKTERKKSSSSSQYKA-NMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWIC 159
               R     S  YK  N  F KLF  +P  E L   ++CALQ+EIL QG+L++SENWIC
Sbjct: 66  RNFIRNSKMLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWIC 125

Query: 160 FHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLL 218
           F+S +F  +T ISI    VT +KK KTA L+PNA+ I T ++++ F S  +RD  + L+
Sbjct: 126 FYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLI 184


>gi|92110010 GRAM domain containing 1A isoform 1 [Homo sapiens]
          Length = 724

 Score =  104 bits (260), Expect = 1e-22
 Identities = 66/186 (35%), Positives = 97/186 (52%), Gaps = 12/186 (6%)

Query: 45  PHLWRRTPQTRRKSLAYAHIFSPNLCFIQDQESKSSFDGASLASDKNDC----KTES--- 97
           PH  R TP +         +  P+    + +       G+  +S+K        T+S   
Sbjct: 6   PHSGRSTPSSSPSLRKRLQLLPPSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPSTQSLGS 65

Query: 98  ----KNDPKTERKKSSSSSQYKA-NMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLF 152
               +N  K +   S  S  YK  N  F KLF  +P  E L   ++CALQ+EIL QG+L+
Sbjct: 66  RNFIRNSKKMQSWYSMLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLY 125

Query: 153 VSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRD 212
           +SENWICF+S +F  +T ISI    VT +KK KTA L+PNA+ I T ++++ F S  +RD
Sbjct: 126 LSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARD 185

Query: 213 STYKLL 218
             + L+
Sbjct: 186 RCFLLI 191


>gi|144227752 GRAM domain containing 1B [Homo sapiens]
          Length = 738

 Score = 99.4 bits (246), Expect = 6e-21
 Identities = 50/146 (34%), Positives = 84/146 (57%), Gaps = 1/146 (0%)

Query: 74  DQESKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKA-NMHFHKLFLSVPTEEP 132
           D+   +   G   +      ++  KN  K++   +  S  YK  N  F KLF  +P  E 
Sbjct: 51  DKSPSTPEQGVQRSCSSQSGRSGGKNSKKSQSWYNVLSPTYKQRNEDFRKLFKQLPDTER 110

Query: 133 LKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPN 192
           L   ++CALQ++IL QG+L++SENWICF+S +F  +T +++    +  + K KTA L+PN
Sbjct: 111 LIVDYSCALQRDILLQGRLYLSENWICFYSNIFRWETLLTVRLKDICSMTKEKTARLIPN 170

Query: 193 ALIIATVTDRYIFVSLLSRDSTYKLL 218
           A+ + T ++++ F S  +RD TY ++
Sbjct: 171 AIQVCTDSEKHFFTSFGARDRTYMMM 196


>gi|187936935 GRAM domain containing 1C [Homo sapiens]
          Length = 662

 Score = 97.4 bits (241), Expect = 2e-20
 Identities = 47/107 (43%), Positives = 71/107 (66%), Gaps = 1/107 (0%)

Query: 110 SSSQYK-ANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKD 168
           SSS YK  N  + + F  +P  E L   + CALQ++IL QG+L++SENW+CF+S +F  +
Sbjct: 60  SSSTYKDRNEEYRRQFTHLPDTERLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWE 119

Query: 169 TKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTY 215
           T ISI   ++T + K KTA L+PNA+ I T ++++ F S  +RD +Y
Sbjct: 120 TTISIALKNITFMTKEKTARLIPNAIQIVTESEKFFFTSFGARDRSY 166


>gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Homo
           sapiens]
          Length = 1266

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 38/125 (30%), Positives = 73/125 (58%), Gaps = 10/125 (8%)

Query: 98  KNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQK-EILYQGKLFVSEN 156
           K D  TE+ K       +A + FH+LF  +P EE L   ++C+  K ++  QG +++S N
Sbjct: 133 KEDDDTEKFK-------EAIVKFHRLF-GMPEEEKLVNYYSCSYWKGKVPRQGWMYLSIN 184

Query: 157 WICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYK 216
            +CF+S + G++ K+ I    +T ++K  T LL+P+ + ++T +  + F   L+ + T+K
Sbjct: 185 HLCFYSFLMGREAKLVIRWVDITQLEKNAT-LLLPDVIKVSTRSSEHFFSVFLNINETFK 243

Query: 217 LLKSV 221
           L++ +
Sbjct: 244 LMEQL 248



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 52/229 (22%), Positives = 100/229 (43%), Gaps = 37/229 (16%)

Query: 91  NDCKTESKNDPKTERKKSSSSSQYK------ANMHFHKLFLSVPTEEPLKQSFTCALQ-- 142
           N+   + ++ PK +RK     S  K      A    ++    +P +E L     C L   
Sbjct: 259 NEGFEQDRSLPKLKRKSPKKVSALKRDLDARAKSERYRALFRLPKDEKLDGHTDCTLWTP 318

Query: 143 -KEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTD 201
             ++   G++FVS N+ICF SK     + I IP   VT+++K  ++ ++P+ L I+T   
Sbjct: 319 FNKMHILGQMFVSTNYICFTSKEENLCSLI-IPLREVTIVEKADSSSVLPSPLSISTRNR 377

Query: 202 -RYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFS 260
             ++F +L  RD    L++ +   L+ T+           +   +D+      +F   ++
Sbjct: 378 MTFLFANLKDRDF---LVQRISDFLQQTT-----------SKIYSDK------EFAGSYN 417

Query: 261 DLDGVVQQRRQDMEGYSSSGSQTPESENSRDFH------ATESQTVLNV 303
             D  V  R   +   S   S + +++  R F+       T +QT++ +
Sbjct: 418 SSDDEVYSRPSSLVSSSPQRSTSSDADGERQFNLNGNSVPTATQTLMTM 466


>gi|156231067 TBC1 domain family, member 8 [Homo sapiens]
          Length = 1140

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 48/196 (24%), Positives = 91/196 (46%), Gaps = 23/196 (11%)

Query: 115 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILY---QGKLFVSENWICFHSKVFGKDTKI 171
           +A   F + F  +P +E L     C+L          G++F S+++ICF S+  G   KI
Sbjct: 281 RAQNEFFRAFFRLPRKEKLHAVVDCSLWTPFSRCHTTGRMFASDSYICFASREDGC-CKI 339

Query: 172 SIPAFSVTLIKKTKTALLVPNALIIATVTD-RYIFVSLLSRDSTYKLLKSVCGHLENTSV 230
            +P   V  I+K +   L+P+ +I++  +   + F+ L  RDS   L++++   L+    
Sbjct: 340 ILPLREVVSIEKMEDTSLLPHPIIVSIRSKVAFQFIELRDRDS---LVEALLARLKQVHA 396

Query: 231 GNSPN-PSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDME--------------G 275
            +  +  +SA++   +    S  +  +  F DL+ +  Q  ++ E               
Sbjct: 397 NHPVHYDTSADDDMASLVFHSTSMCSDHRFGDLEMMSSQNSEESEKEKSPLMHPDALVTA 456

Query: 276 YSSSGSQTPESENSRD 291
           +  SGSQ+P+S  SR+
Sbjct: 457 FQQSGSQSPDSRMSRE 472



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 32/139 (23%), Positives = 66/139 (47%), Gaps = 12/139 (8%)

Query: 84  ASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQK 143
           A +A + +    E + +P+  R+   +  +++A  +F       P  E L   ++C   K
Sbjct: 120 ALIAEETSSRLAEQEEEPEKFRE---ALVKFEARFNF-------PEAEKLVTYYSCCCWK 169

Query: 144 -EILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDR 202
             +  QG L++S N +CF+S   GK+ K+ +P   +  +++T    L  + + I T    
Sbjct: 170 GRVPRQGWLYLSINHLCFYSFFLGKELKLVVPWVDIQKLERTSNVFLT-DTIRITTQNKE 228

Query: 203 YIFVSLLSRDSTYKLLKSV 221
             F   L+ D  +K+++ +
Sbjct: 229 RDFSMFLNLDEVFKVMEQL 247


>gi|45597177 TBC1 domain family, member 9B (with GRAM domain)
           isoform b [Homo sapiens]
          Length = 1233

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 29/108 (26%), Positives = 56/108 (51%), Gaps = 3/108 (2%)

Query: 115 KANMHFHKLFLSVPTEEPLKQSFTCALQK-EILYQGKLFVSENWICFHSKVFGKDTKISI 173
           +A +   K F  +P  E L   ++C+  K  +  QG L+++ N +CF+S + GK+  + +
Sbjct: 139 EAELKMRKQF-GMPEGEKLVNYYSCSYWKGRVPRQGWLYLTVNHLCFYSFLLGKEVSLVV 197

Query: 174 PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSV 221
               +T ++K  T LL P ++ + T      F   L+   T+KL++ +
Sbjct: 198 QWVDITRLEKNAT-LLFPESIRVDTRDQELFFSMFLNIGETFKLMEQL 244



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 50/210 (23%), Positives = 94/210 (44%), Gaps = 33/210 (15%)

Query: 115 KANMHFHKLFLSVPTEEPLKQSFTCALQ---KEILYQGKLFVSENWICFHSKVFGKDTKI 171
           +A    ++    +P +E L    +C L     ++   G++F+S N+ICF SK       +
Sbjct: 284 RAKNECYRATFRLPRDERLDGHTSCTLWTPFNKLHIPGQMFISNNYICFASKE-EDACHL 342

Query: 172 SIPAFSVTLIKKTKTALLVPNALIIATVTD-RYIFVSLLSRDSTYKLLKSVCGHLENT-- 228
            IP   VT+++K  ++ ++P+ L I+T +   ++F +L  RD    L++ +   L+ T  
Sbjct: 343 IIPLREVTIVEKADSSSVLPSPLSISTKSKMTFLFANLKDRDF---LVQRISDFLQKTPS 399

Query: 229 ----SVGN----------SPNPSSAENSFRADRPSSLPLDFNDEF------SDLDGVVQ- 267
               S+G+            +P+  E S +   P+S PL     F      +   G+++ 
Sbjct: 400 KQPGSIGSRKASVVDPSTESSPAPQEGSEQPASPAS-PLSSRQSFCAQEAPTASQGLLKL 458

Query: 268 -QRRQDMEGYSSSGSQTPESENSRDFHATE 296
            Q+   ME   + G++    E S   H  E
Sbjct: 459 FQKNSPMEDLGAKGAKEKMKEESWHIHFFE 488


>gi|45597175 TBC1 domain family, member 9B (with GRAM domain)
           isoform a [Homo sapiens]
          Length = 1250

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 29/108 (26%), Positives = 56/108 (51%), Gaps = 3/108 (2%)

Query: 115 KANMHFHKLFLSVPTEEPLKQSFTCALQK-EILYQGKLFVSENWICFHSKVFGKDTKISI 173
           +A +   K F  +P  E L   ++C+  K  +  QG L+++ N +CF+S + GK+  + +
Sbjct: 139 EAELKMRKQF-GMPEGEKLVNYYSCSYWKGRVPRQGWLYLTVNHLCFYSFLLGKEVSLVV 197

Query: 174 PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSV 221
               +T ++K  T LL P ++ + T      F   L+   T+KL++ +
Sbjct: 198 QWVDITRLEKNAT-LLFPESIRVDTRDQELFFSMFLNIGETFKLMEQL 244



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 50/210 (23%), Positives = 94/210 (44%), Gaps = 33/210 (15%)

Query: 115 KANMHFHKLFLSVPTEEPLKQSFTCALQ---KEILYQGKLFVSENWICFHSKVFGKDTKI 171
           +A    ++    +P +E L    +C L     ++   G++F+S N+ICF SK       +
Sbjct: 284 RAKNECYRATFRLPRDERLDGHTSCTLWTPFNKLHIPGQMFISNNYICFASKE-EDACHL 342

Query: 172 SIPAFSVTLIKKTKTALLVPNALIIATVTD-RYIFVSLLSRDSTYKLLKSVCGHLENT-- 228
            IP   VT+++K  ++ ++P+ L I+T +   ++F +L  RD    L++ +   L+ T  
Sbjct: 343 IIPLREVTIVEKADSSSVLPSPLSISTKSKMTFLFANLKDRDF---LVQRISDFLQKTPS 399

Query: 229 ----SVGN----------SPNPSSAENSFRADRPSSLPLDFNDEF------SDLDGVVQ- 267
               S+G+            +P+  E S +   P+S PL     F      +   G+++ 
Sbjct: 400 KQPGSIGSRKASVVDPSTESSPAPQEGSEQPASPAS-PLSSRQSFCAQEAPTASQGLLKL 458

Query: 268 -QRRQDMEGYSSSGSQTPESENSRDFHATE 296
            Q+   ME   + G++    E S   H  E
Sbjct: 459 FQKNSPMEDLGAKGAKEKMKEESWHIHFFE 488


>gi|38570103 TBC1 domain family, member 8B (with GRAM domain)
           isoform b [Homo sapiens]
          Length = 632

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 28/111 (25%), Positives = 59/111 (53%), Gaps = 3/111 (2%)

Query: 115 KANMHFHKLFLSVPTEEPLKQSFTCALQK-EILYQGKLFVSENWICFHSKVFGKDTKISI 173
           +A + F K F  +P +E L   ++C+  K  +  QG L++S N++ F+S + G + K+ I
Sbjct: 142 EALLKFEKCF-GLPEKEKLVTYYSCSYWKGRVPCQGWLYLSTNFLSFYSFLLGSEIKLII 200

Query: 174 PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGH 224
               V+ ++KT   +L   ++ + +  + + F   L  + TY L++ +  +
Sbjct: 201 SWDEVSKLEKTSNVILT-ESIHVCSQGENHYFSMFLHINQTYLLMEQLANY 250



 Score = 35.4 bits (80), Expect = 0.10
 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 4/73 (5%)

Query: 115 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILY---QGKLFVSENWICFHSKVFGKDTKI 171
           +A+      F  +P  E LK+   C L     +    GK+ +SEN+ICF S+  G    +
Sbjct: 281 RAHSEQFNAFFRLPKGESLKEVHECFLWVPFSHFNTHGKMCISENYICFASQ-DGNQCSV 339

Query: 172 SIPAFSVTLIKKT 184
            IP   V  I KT
Sbjct: 340 IIPLREVLAIDKT 352


>gi|38570101 TBC1 domain family, member 8B (with GRAM domain)
           isoform a [Homo sapiens]
          Length = 1120

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 28/111 (25%), Positives = 59/111 (53%), Gaps = 3/111 (2%)

Query: 115 KANMHFHKLFLSVPTEEPLKQSFTCALQK-EILYQGKLFVSENWICFHSKVFGKDTKISI 173
           +A + F K F  +P +E L   ++C+  K  +  QG L++S N++ F+S + G + K+ I
Sbjct: 142 EALLKFEKCF-GLPEKEKLVTYYSCSYWKGRVPCQGWLYLSTNFLSFYSFLLGSEIKLII 200

Query: 174 PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGH 224
               V+ ++KT   +L   ++ + +  + + F   L  + TY L++ +  +
Sbjct: 201 SWDEVSKLEKTSNVILT-ESIHVCSQGENHYFSMFLHINQTYLLMEQLANY 250



 Score = 35.4 bits (80), Expect = 0.10
 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 4/73 (5%)

Query: 115 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILY---QGKLFVSENWICFHSKVFGKDTKI 171
           +A+      F  +P  E LK+   C L     +    GK+ +SEN+ICF S+  G    +
Sbjct: 281 RAHSEQFNAFFRLPKGESLKEVHECFLWVPFSHFNTHGKMCISENYICFASQ-DGNQCSV 339

Query: 172 SIPAFSVTLIKKT 184
            IP   V  I KT
Sbjct: 340 IIPLREVLAIDKT 352


>gi|67763814 death-inducing-protein [Homo sapiens]
          Length = 578

 Score = 37.7 bits (86), Expect = 0.021
 Identities = 30/119 (25%), Positives = 59/119 (49%), Gaps = 18/119 (15%)

Query: 119 HFHKLFLSVPTEEPL---KQSFTCAL-------QKEILYQGKLFVSENWICFHSKVFG-- 166
           +FH++F     E PL   +  + C L         + +  G L+V+EN++CF S   G  
Sbjct: 446 NFHEIFNLTENERPLAVCENGWRCCLINRDRKMPTDYIRNGVLYVTENYLCFESSKSGSS 505

Query: 167 KDTKISIPAFSVTLIKKTKTALLVPNA---LIIATVTDR--YIFVSLLSRDSTYKLLKS 220
           K  K+ I    +T I+K K   ++P +   + ++T + +   +F +++ RD  ++ + S
Sbjct: 506 KRNKV-IKLVDITDIQKYKVLSVLPGSGMGIAVSTPSTQKPLVFGAMVHRDEAFETILS 563


>gi|61743940 G-protein coupled receptor 110 isoform 1 [Homo sapiens]
          Length = 910

 Score = 32.7 bits (73), Expect = 0.67
 Identities = 29/144 (20%), Positives = 64/144 (44%), Gaps = 19/144 (13%)

Query: 162 SKVFGKDTKISIPAF--SVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSR----DSTY 215
           S + G  T+ ++ +F  ++++I +   +  V N   + ++      +SL S     +ST 
Sbjct: 312 SMIVGNATEAAVSSFVQNLSVIIRQNPSTTVGNLASVVSILSNISSLSLASHFRVSNSTM 371

Query: 216 KLLKSVCGHLENTSVGNSPNPSSAENSFRADR-------------PSSLPLDFNDEFSDL 262
           + + S+  ++ N++   +      E  + + R             P++LPL+F+ +F D 
Sbjct: 372 EDVISIADNILNSASVTNWTVLLREEKYASSRLLETLENISTLVPPTALPLNFSRKFIDW 431

Query: 263 DGVVQQRRQDMEGYSSSGSQTPES 286
            G+   + Q   GYS      P++
Sbjct: 432 KGIPVNKSQLKRGYSYQIKMCPQN 455


>gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1
           [Homo sapiens]
          Length = 759

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 16/52 (30%), Positives = 26/52 (50%)

Query: 64  IFSPNLCFIQDQESKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYK 115
           +F+ N    +DQE +           K+D K E+KNDP+ ++KK     + K
Sbjct: 158 LFNVNNSSNKDQEPEEKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKK 209


>gi|71143141 cyclic nucleotide gated channel alpha 1 isoform 2 [Homo
           sapiens]
          Length = 690

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 16/52 (30%), Positives = 26/52 (50%)

Query: 64  IFSPNLCFIQDQESKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYK 115
           +F+ N    +DQE +           K+D K E+KNDP+ ++KK     + K
Sbjct: 89  LFNVNNSSNKDQEPEEKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKK 140


>gi|39995071 exonuclease 1 isoform b [Homo sapiens]
          Length = 846

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 26/95 (27%), Positives = 49/95 (51%), Gaps = 7/95 (7%)

Query: 223 GHLENTSVGNSPNPSSAENSFR--ADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYS-SS 279
           G L + S   SP+PS+A   FR  +D P+SLP    +  SD+  +  +   D E +    
Sbjct: 613 GGLGDFSRTPSPSPSTALQQFRRKSDSPTSLP---ENNMSDVSQLKSEESSDDESHPLRE 669

Query: 280 GSQTPESENSRDFHATESQTVLNVSKGEAKPTRAD 314
           G+ + +S+ S +F + +S     +S+  +K + ++
Sbjct: 670 GACSSQSQESGEF-SLQSSNASKLSQCSSKDSDSE 703


>gi|39995069 exonuclease 1 isoform a [Homo sapiens]
          Length = 803

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 26/95 (27%), Positives = 49/95 (51%), Gaps = 7/95 (7%)

Query: 223 GHLENTSVGNSPNPSSAENSFR--ADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYS-SS 279
           G L + S   SP+PS+A   FR  +D P+SLP    +  SD+  +  +   D E +    
Sbjct: 613 GGLGDFSRTPSPSPSTALQQFRRKSDSPTSLP---ENNMSDVSQLKSEESSDDESHPLRE 669

Query: 280 GSQTPESENSRDFHATESQTVLNVSKGEAKPTRAD 314
           G+ + +S+ S +F + +S     +S+  +K + ++
Sbjct: 670 GACSSQSQESGEF-SLQSSNASKLSQCSSKDSDSE 703


>gi|18491016 exonuclease 1 isoform b [Homo sapiens]
          Length = 846

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 26/95 (27%), Positives = 49/95 (51%), Gaps = 7/95 (7%)

Query: 223 GHLENTSVGNSPNPSSAENSFR--ADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYS-SS 279
           G L + S   SP+PS+A   FR  +D P+SLP    +  SD+  +  +   D E +    
Sbjct: 613 GGLGDFSRTPSPSPSTALQQFRRKSDSPTSLP---ENNMSDVSQLKSEESSDDESHPLRE 669

Query: 280 GSQTPESENSRDFHATESQTVLNVSKGEAKPTRAD 314
           G+ + +S+ S +F + +S     +S+  +K + ++
Sbjct: 670 GACSSQSQESGEF-SLQSSNASKLSQCSSKDSDSE 703


>gi|68989256 ras inhibitor RIN1 [Homo sapiens]
          Length = 783

 Score = 31.2 bits (69), Expect = 2.0
 Identities = 29/125 (23%), Positives = 49/125 (39%), Gaps = 22/125 (17%)

Query: 35  PAGRQQPNPLPHLWRRTPQTRRKSLAYAHIFSPNLCFIQDQESKSSFDGASLASDKN--- 91
           P  R  P   PHL RR P  R  S A+  + +P        E +     A+L  D++   
Sbjct: 328 PGSRGSPATSPHLGRRRPLLRSMSAAFCSLLAP--------ERQVGRAAAALMQDRHTAA 379

Query: 92  -----DCKTESKNDPKTERKK------SSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCA 140
                D  T+ +  P+ +  +      S + +   A +   KL      E  L++S  C+
Sbjct: 380 GQLVQDLLTQVRAGPEPQELQGIRQALSRARAMLSAELGPEKLLSPKRLEHVLEKSLHCS 439

Query: 141 LQKEI 145
           + K +
Sbjct: 440 VLKPL 444


>gi|242117946 hypothetical protein LOC57579 isoform c [Homo sapiens]
          Length = 1515

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 7/105 (6%)

Query: 221 VCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSG 280
           +C  ++NTS  +S  P   E S      +SLP+ F D +  LD V     +D++      
Sbjct: 375 MCTAIKNTSFCSSLPPLPIECSELDGDLNSLPIIFEDRY--LDSVT----EDLDAPWMGI 428

Query: 281 SQTPESENSR-DFHATESQTVLNVSKGEAKPTRADAHVNRVPEGK 324
                SE+S+ D + TE  +V  +S  E K   A A      EG+
Sbjct: 429 QNLQRSESSKMDKYETEESSVAGLSSPELKVRPAGASSIWYTEGE 473


>gi|38788260 bromodomain PHD finger transcription factor isoform 2
            [Homo sapiens]
          Length = 2903

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 4/83 (4%)

Query: 225  LENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTP 284
            +E+  +  S       +   ++  S+L  DF DE    +G+   + +++ G S   +   
Sbjct: 1657 VEDMEIETSEVKKVTSSPITSEEESNLSNDFIDE----NGLPINKNENVNGESKRKTVIT 1712

Query: 285  ESENSRDFHATESQTVLNVSKGE 307
            E        ATES+TV+ V KG+
Sbjct: 1713 EVTTMTSTVATESKTVIKVEKGD 1735


>gi|38788274 bromodomain PHD finger transcription factor isoform 1
            [Homo sapiens]
          Length = 2920

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 4/83 (4%)

Query: 225  LENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTP 284
            +E+  +  S       +   ++  S+L  DF DE    +G+   + +++ G S   +   
Sbjct: 1531 VEDMEIETSEVKKVTSSPITSEEESNLSNDFIDE----NGLPINKNENVNGESKRKTVIT 1586

Query: 285  ESENSRDFHATESQTVLNVSKGE 307
            E        ATES+TV+ V KG+
Sbjct: 1587 EVTTMTSTVATESKTVIKVEKGD 1609


>gi|55741653 hypothetical protein LOC57691 [Homo sapiens]
          Length = 787

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 20/75 (26%), Positives = 36/75 (48%), Gaps = 5/75 (6%)

Query: 193 ALIIATVTDRYIFVSLLSRDST-----YKLLKSVCGHLENTSVGNSPNPSSAENSFRADR 247
           AL+I  + +  +  + L   ST      KL+K     LEN  +G     S  E+  ++D+
Sbjct: 527 ALMIDILEEFSVLSTALQSRSTNIKKAQKLIKRTIRALENLKIGTGKYESQIEDLIKSDK 586

Query: 248 PSSLPLDFNDEFSDL 262
              +P + N++F+ L
Sbjct: 587 FKDIPFNKNNKFNAL 601


>gi|48255931 hepatoma-derived growth factor-related protein 2
           isoform 1 [Homo sapiens]
          Length = 671

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 41/153 (26%), Positives = 71/153 (46%), Gaps = 13/153 (8%)

Query: 257 DEFSDLDGVVQQRRQDMEGYS--SSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRAD 314
           DE  + D  V++R +   G    SS    PE+E  R+   +  +   + ++   KP + +
Sbjct: 372 DELREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKSAKKPQSSSTEPARKPGQKE 431

Query: 315 AHVNRVPEGKAKSLPV-----QGLSETVGILHKVKSQKCPMLHHIL-IFYAIVVCALIIS 368
             V   PE K ++ PV     +  SE   +  KV+ +K P +   L   ++ +  AL + 
Sbjct: 432 KRVR--PEEKQQAKPVKVERTRKRSEGFSMDRKVEKKKEPSVEEKLQKLHSEIKFALKVD 489

Query: 369 TFYMRYRINTLEEQLGLL--TSIVDTHNTEQAA 399
           +  ++  +N LEE LG L  TS +   NT+  A
Sbjct: 490 SPDVKRCLNALEE-LGTLQVTSQILQKNTDVVA 521


>gi|14249158 hepatoma-derived growth factor-related protein 2
           isoform 2 [Homo sapiens]
          Length = 670

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 41/153 (26%), Positives = 71/153 (46%), Gaps = 13/153 (8%)

Query: 257 DEFSDLDGVVQQRRQDMEGYS--SSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRAD 314
           DE  + D  V++R +   G    SS    PE+E  R+   +  +   + ++   KP + +
Sbjct: 372 DELREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKSAKKPQSSSTEPARKPGQKE 431

Query: 315 AHVNRVPEGKAKSLPV-----QGLSETVGILHKVKSQKCPMLHHIL-IFYAIVVCALIIS 368
             V   PE K ++ PV     +  SE   +  KV+ +K P +   L   ++ +  AL + 
Sbjct: 432 KRVR--PEEKQQAKPVKVERTRKRSEGFSMDRKVEKKKEPSVEEKLQKLHSEIKFALKVD 489

Query: 369 TFYMRYRINTLEEQLGLL--TSIVDTHNTEQAA 399
           +  ++  +N LEE LG L  TS +   NT+  A
Sbjct: 490 SPDVKRCLNALEE-LGTLQVTSQILQKNTDVVA 521


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.129    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,630,575
Number of Sequences: 37866
Number of extensions: 752397
Number of successful extensions: 2576
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 2537
Number of HSP's gapped (non-prelim): 82
length of query: 440
length of database: 18,247,518
effective HSP length: 105
effective length of query: 335
effective length of database: 14,271,588
effective search space: 4780981980
effective search space used: 4780981980
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.