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Search of human proteins with 186928825
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|186928825 dermokine isoform 3 precursor [Homo sapiens]
(416 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|186928825 dermokine isoform 3 precursor [Homo sapiens] 866 0.0
gi|186928827 dermokine isoform 5 precursor [Homo sapiens] 819 0.0
gi|186928829 dermokine isoform 4 precursor [Homo sapiens] 790 0.0
gi|33504489 dermokine isoform 2 precursor [Homo sapiens] 777 0.0
gi|186928831 dermokine isoform 6 [Homo sapiens] 145 5e-35
gi|109255251 loricrin [Homo sapiens] 105 8e-23
gi|55956899 keratin 9 [Homo sapiens] 104 2e-22
gi|57864582 hornerin [Homo sapiens] 103 2e-22
gi|62122917 filaggrin family member 2 [Homo sapiens] 94 3e-19
gi|195972866 keratin 10 [Homo sapiens] 93 4e-19
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 93 5e-19
gi|119395750 keratin 1 [Homo sapiens] 88 1e-17
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 87 4e-17
gi|47132620 keratin 2 [Homo sapiens] 86 8e-17
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 81 2e-15
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 81 2e-15
gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap... 80 3e-15
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 80 4e-15
gi|48762934 alpha 2 type I collagen [Homo sapiens] 78 1e-14
gi|4504733 insulin receptor substrate 4 [Homo sapiens] 78 2e-14
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 77 2e-14
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 77 2e-14
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 77 2e-14
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 77 2e-14
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 77 2e-14
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 77 2e-14
gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b... 75 8e-14
gi|89276766 trophinin isoform 5 [Homo sapiens] 75 8e-14
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 75 1e-13
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho... 74 2e-13
>gi|186928825 dermokine isoform 3 precursor [Homo sapiens]
Length = 416
Score = 866 bits (2238), Expect = 0.0
Identities = 416/416 (100%), Positives = 416/416 (100%)
Query: 1 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG 60
MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG
Sbjct: 1 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG 60
Query: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV
Sbjct: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
Query: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS
Sbjct: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
Query: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG
Sbjct: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
Query: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS
Sbjct: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
Query: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREI 360
GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREI
Sbjct: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREI 360
Query: 361 SKEGNRLLGGSGDNYRNSETSPGMFNFDTFWKNFKSKLGFINWDAINKDQRSSRIP 416
SKEGNRLLGGSGDNYRNSETSPGMFNFDTFWKNFKSKLGFINWDAINKDQRSSRIP
Sbjct: 361 SKEGNRLLGGSGDNYRNSETSPGMFNFDTFWKNFKSKLGFINWDAINKDQRSSRIP 416
>gi|186928827 dermokine isoform 5 precursor [Homo sapiens]
Length = 398
Score = 819 bits (2115), Expect = 0.0
Identities = 398/416 (95%), Positives = 398/416 (95%), Gaps = 18/416 (4%)
Query: 1 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG 60
MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG
Sbjct: 1 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG 60
Query: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV
Sbjct: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
Query: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS
Sbjct: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
Query: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG
Sbjct: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
Query: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS
Sbjct: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
Query: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREI 360
GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNM
Sbjct: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNM--- 357
Query: 361 SKEGNRLLGGSGDNYRNSETSPGMFNFDTFWKNFKSKLGFINWDAINKDQRSSRIP 416
RNSETSPGMFNFDTFWKNFKSKLGFINWDAINKDQRSSRIP
Sbjct: 358 ---------------RNSETSPGMFNFDTFWKNFKSKLGFINWDAINKDQRSSRIP 398
>gi|186928829 dermokine isoform 4 precursor [Homo sapiens]
Length = 386
Score = 790 bits (2041), Expect = 0.0
Identities = 386/416 (92%), Positives = 386/416 (92%), Gaps = 30/416 (7%)
Query: 1 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG 60
MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG
Sbjct: 1 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG 60
Query: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV
Sbjct: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
Query: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS
Sbjct: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
Query: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG
Sbjct: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
Query: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS
Sbjct: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
Query: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREI 360
GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ
Sbjct: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ-------------- 346
Query: 361 SKEGNRLLGGSGDNYRNSETSPGMFNFDTFWKNFKSKLGFINWDAINKDQRSSRIP 416
NSETSPGMFNFDTFWKNFKSKLGFINWDAINKDQRSSRIP
Sbjct: 347 ----------------NSETSPGMFNFDTFWKNFKSKLGFINWDAINKDQRSSRIP 386
>gi|33504489 dermokine isoform 2 precursor [Homo sapiens]
Length = 476
Score = 777 bits (2007), Expect = 0.0
Identities = 379/410 (92%), Positives = 380/410 (92%), Gaps = 30/410 (7%)
Query: 1 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG 60
MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG
Sbjct: 1 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG 60
Query: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV
Sbjct: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
Query: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS
Sbjct: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
Query: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG
Sbjct: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
Query: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS
Sbjct: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
Query: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREI 360
GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ
Sbjct: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ-------------- 346
Query: 361 SKEGNRLLGGSGDNYRNSETSPGMFNFDTFWKNFKSKLGFINWDAINKDQ 410
NSETSPGMFNFDTFWKNFKSKLGFINWDAINK+Q
Sbjct: 347 ----------------NSETSPGMFNFDTFWKNFKSKLGFINWDAINKNQ 380
>gi|186928831 dermokine isoform 6 [Homo sapiens]
Length = 189
Score = 145 bits (367), Expect = 5e-35
Identities = 73/104 (70%), Positives = 74/104 (71%), Gaps = 30/104 (28%)
Query: 307 GSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNR 366
GSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ
Sbjct: 20 GSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ-------------------- 59
Query: 367 LLGGSGDNYRNSETSPGMFNFDTFWKNFKSKLGFINWDAINKDQ 410
NSETSPGMFNFDTFWKNFKSKLGFINWDAINK+Q
Sbjct: 60 ----------NSETSPGMFNFDTFWKNFKSKLGFINWDAINKNQ 93
Score = 32.7 bits (73), Expect = 0.62
Identities = 22/57 (38%), Positives = 29/57 (50%), Gaps = 9/57 (15%)
Query: 257 SGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSS--------GNSGGSRGDSGSESS 305
S S+ G GSS+GSSSG + GGS GG+ GN G+SG ++S
Sbjct: 6 SCSDQQAKEGEGLEGSSTGSSSG-NHGGSGGGNGHKPGCEKPGNEARGSGESGIQNS 61
Score = 31.6 bits (70), Expect = 1.4
Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 7/59 (11%)
Query: 219 SVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG-------SSGSGSNGDNNNGSSSG 270
S + + + EG S G SGGG+G + G + GSG +G N+ +S G
Sbjct: 8 SDQQAKEGEGLEGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 66
Score = 29.6 bits (65), Expect = 5.3
Identities = 16/60 (26%), Positives = 23/60 (38%)
Query: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306
G G + S+GS S +G +G G + GS NS S G ++ W
Sbjct: 15 GEGLEGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPGMFNFDTFW 74
>gi|109255251 loricrin [Homo sapiens]
Length = 312
Score = 105 bits (262), Expect = 8e-23
Identities = 99/288 (34%), Positives = 112/288 (38%), Gaps = 55/288 (19%)
Query: 137 GHNGAWETSGGHGIFG---SQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPW 193
G G GG G FG S GG G G G GG GY G G G
Sbjct: 23 GGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGG------GGYSGGGCG-------GGSS 69
Query: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG----GGSSNSGGGSG 249
G GG GG G + G+V G G +S GC + GSG GG +SGGGSG
Sbjct: 70 GGGGGGGIGGCGGGSGGSVKYSGGGG--SSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSG 127
Query: 250 SQSGSSGSGSNGDNNNGSSSGGSSSG------SSSGGSSGGSSGGSSG--NSGGSRGD-- 299
S G S G + SS GG SG S G SSGGSSGG SG +SGG G
Sbjct: 128 CFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVC 187
Query: 300 ----SGSESSWGSSTGSSSG------------------NHGGSGGGNGHKPGCEKPGNEA 337
GS GSS GS SG G SGGG GC G
Sbjct: 188 GYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGG 247
Query: 338 RGSGESGIQGFRGQG-VSSNMREISKEGNRLLGGSGDNYRNSETSPGM 384
SG G G G + S + G+ GG G + S + G+
Sbjct: 248 GSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKGV 295
Score = 93.6 bits (231), Expect = 3e-19
Identities = 88/268 (32%), Positives = 104/268 (38%), Gaps = 29/268 (10%)
Query: 89 FGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGH 148
FG + G G G G+ G G G G G G+ + SGG
Sbjct: 37 FGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGG--GSGGSVKYSGGG 94
Query: 149 GIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTN- 207
G G G G G G + G G+S G G G GG G + G
Sbjct: 95 GSSGGGSGCFSSGGGGSGCFSS----GGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGG 150
Query: 208 -TQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS--SNSGGGSGSQSGSSGSGSNGDNN 264
+ AV YG V + + G + SG GGGS SGGGSG GSSG +G +
Sbjct: 151 FSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVS 210
Query: 265 NG-----------SSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSS 313
+ S GGSS G SGGS SSGG G+SG G SG S S G S
Sbjct: 211 SQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGS 270
Query: 314 SGNHGGSGGGNGHKPGCEKPGNEARGSG 341
G SGGG G G+ GSG
Sbjct: 271 VCGGGSSGGGGG--------GSSVGGSG 290
Score = 92.4 bits (228), Expect = 7e-19
Identities = 79/238 (33%), Positives = 95/238 (39%), Gaps = 26/238 (10%)
Query: 130 GSWQGVPGHNGAWETSGGHGIFGSQGGLGGQ-----GQGNPGGLGTPWVHGYPGN---SA 181
G + G G+ GG GI G GG GG G G+ GG + G G+ S+
Sbjct: 57 GGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSS 116
Query: 182 GSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS 241
G G + G+ G GG G+ + G G ++ SG G G
Sbjct: 117 GGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGC 176
Query: 242 SNSGGGSGSQSGSSGSGSN--GDNNNGSSSGGSSS----------------GSSSGGSSG 283
+SGGG GS G SG GS G ++ GS SG SS GSS GG SG
Sbjct: 177 FSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSG 236
Query: 284 GSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSG 341
GS SSG GGS G G S GS S G GG +G G G G G
Sbjct: 237 GSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKG 294
Score = 89.4 bits (220), Expect = 6e-18
Identities = 67/161 (41%), Positives = 70/161 (43%), Gaps = 18/161 (11%)
Query: 229 CTNPPPSGSGGGSSNSGG-----GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSG 283
C G GGG S GG G GS GSSGSG G + G SGG G SSGG G
Sbjct: 16 CVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGC-GYSGGGGYSGGGCGGGSSGGGGG 74
Query: 284 GSSGGSSGNSGGS------RGDSGSESSWGSSTGSSSGNHGGSGGG-NGHKPGCEKP--- 333
G GG G SGGS G SG S SS G SG GGG +G GC
Sbjct: 75 GGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGG 134
Query: 334 GNEARGSG--ESGIQGFRGQGVSSNMREISKEGNRLLGGSG 372
G+ GSG SG GF GQ V G GGSG
Sbjct: 135 GSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSG 175
Score = 83.6 bits (205), Expect = 3e-16
Identities = 90/281 (32%), Positives = 108/281 (38%), Gaps = 29/281 (10%)
Query: 40 GHGLGDALSEGVGKAI---GKEAGGAAGSKVSEALGQG-TREAVGTGVRQVPGFGAADAL 95
G G G S G G G GG++GS + G G + G G G G
Sbjct: 21 GGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGC 80
Query: 96 GNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQG 155
G G + G G G G + G G G + GG G F S G
Sbjct: 81 GGGSGGSVKYSGGGGSSGGGS-------GCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGG 133
Query: 156 GL---GGQGQGNPGGLG----TPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNF--GT 206
G GG G + GG G Y G S+G G GG G + G
Sbjct: 134 GGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGG 193
Query: 207 NTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG-----SQSGSSGSGSNG 261
+ G + G GS S+Q T+ P S GG S+ GGGSG S G GS G
Sbjct: 194 SGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCG 253
Query: 262 DNNNGSSSGGSSSGSSS---GGSSGGSSGGSS-GNSGGSRG 298
++G SG SG S GGSSGG GGSS G SG +G
Sbjct: 254 GGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKG 294
Score = 81.6 bits (200), Expect = 1e-15
Identities = 84/239 (35%), Positives = 94/239 (39%), Gaps = 58/239 (24%)
Query: 153 SQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAV 212
S GG GG G G G G FG G G GG G G
Sbjct: 20 SGGGGGGGGSG--------------GGGCGFFG--------GGGSGGGSSGSGCGYSGGG 57
Query: 213 AQPGYGSVRASNQNEGCTNPPPSGSGGGS--SNSGGGS-GSQSGSSGSGSNGDNNNGSSS 269
G G S SG GGG GGGS GS S G GS+G + SS
Sbjct: 58 GYSGGGCGGGS-----------SGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSS 106
Query: 270 GGSSSG---SSSGGSSGGSSG-GSSGNSGGSRGDSGSESSWG---SSTGSSSGNHGG--S 320
GG SG S GGSSGG SG SSG G S G SG SS G S ++GG S
Sbjct: 107 GGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSS 166
Query: 321 GGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRNSE 379
GG +G GC + G G + G+ G G S G GGSG Y +S+
Sbjct: 167 GGSSGGGSGC-----FSSGGGGGSVCGYSGGG--------SGCGGGSSGGSGSGYVSSQ 212
Score = 37.4 bits (85), Expect = 0.025
Identities = 62/247 (25%), Positives = 79/247 (31%), Gaps = 70/247 (28%)
Query: 15 CLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEG---VGKAIGKEAGGAAGSKVSEAL 71
C SG G G + G + G G G S G G+A+ ++ G S S
Sbjct: 113 CFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGG 172
Query: 72 GQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS 131
G G + G G V G+ G+ G + +G+ +Q S
Sbjct: 173 GSGCFSSGGGG-GSVCGYSGG---GSGCGGGSSGGSGSGYVSSQQVTQT----------S 218
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGA 191
P + G +SGG GG GG G + GG G
Sbjct: 219 CAPQPSYGGG--SSGG-------GGSGGSGCFSSGGGG---------------------- 247
Query: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQ 251
G G GG G GS GC GG S+ GGG GS
Sbjct: 248 --GSSGCGG------------GSSGIGS--------GCIISGGGSVCGGGSSGGGGGGSS 285
Query: 252 SGSSGSG 258
G SGSG
Sbjct: 286 VGGSGSG 292
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 104 bits (259), Expect = 2e-22
Identities = 76/211 (36%), Positives = 82/211 (38%), Gaps = 48/211 (22%)
Query: 146 GGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFG 205
GG F S G G G G GG G + G G S GS+G GG+GG
Sbjct: 460 GGQEDFESSGA-GKIGLGGRGGSGGSYGRGSRGGSGGSYG---------GGGSGG----- 504
Query: 206 TNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNN 265
G GGGS + GG GS G SGSG
Sbjct: 505 ------------------------------GYGGGSGSRGGSGGSYGGGSGSGGGSGGGY 534
Query: 266 GSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNG 325
G SGG SG S GG SGGS G G SG G G S G S G+HGG G G
Sbjct: 535 GGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGG 594
Query: 326 HKPGCEKPGNEARGSGESGIQGFRGQGVSSN 356
G G EA GSG G G G G SS+
Sbjct: 595 ESGGSYGGGEEASGSG-GGYGG--GSGKSSH 622
Score = 86.3 bits (212), Expect = 5e-17
Identities = 66/180 (36%), Positives = 78/180 (43%), Gaps = 27/180 (15%)
Query: 199 GGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSG 258
GG +F ++ G + G G S GS GGS S GG GS G G
Sbjct: 460 GGQEDFESSGAGKIGLGGRGGSGGSYGR---------GSRGGSGGSYGGGGSGGGYGG-- 508
Query: 259 SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS------GSESSWGSSTGS 312
G + G S G GS SGG SGG GG SG GG G S GS ++G +GS
Sbjct: 509 --GSGSRGGSGGSYGGGSGSGGGSGGGYGGGSG--GGHSGGSGGGHSGGSGGNYGGGSGS 564
Query: 313 SSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSG 372
G+ GG GGG+G + G G+ GSG G G G E S G GGSG
Sbjct: 565 GGGSGGGYGGGSGSRGG--SGGSHGGGSGFGGESG----GSYGGGEEASGSGGGYGGGSG 618
Score = 82.4 bits (202), Expect = 7e-16
Identities = 65/182 (35%), Positives = 79/182 (43%), Gaps = 14/182 (7%)
Query: 119 DVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPG 178
+++ G + S G G G + G +G GS+GG GG G G G G G
Sbjct: 456 NLLEGGQEDFESSGAGKIGLGGRGGSGGSYGR-GSRGGSGGSYGGGGSGGGYGGGSGSRG 514
Query: 179 NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG 238
S GS+G G+ G GG G + G ++ G+ G G S N G GSG
Sbjct: 515 GSGGSYG-GGSGSGGGSGGGYGGGSGGGHSGGS----GGGHSGGSGGNYG------GGSG 563
Query: 239 GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
G SGGG G SGS G GS G + GS GG S GS GG SGG G G
Sbjct: 564 SGG-GSGGGYGGGSGSRG-GSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKSS 621
Query: 299 DS 300
S
Sbjct: 622 HS 623
Score = 76.6 bits (187), Expect = 4e-14
Identities = 61/150 (40%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 237 SGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSS--GGSSGNSG 294
SG G GG GS GS G GS G +G S GG SG GG GGS GGS G+ G
Sbjct: 468 SGAGKIGLGGRGGS-GGSYGRGSRG--GSGGSYGGGGSG---GGYGGGSGSRGGSGGSYG 521
Query: 295 GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVS 354
G G SG S G GS G+ GGSGGG+ G G G G G G+ G S
Sbjct: 522 GGSG-SGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGG--GYGGGSGS 578
Query: 355 SNMREISKEGNRLLGG-SGDNYRNSETSPG 383
S G GG SG +Y E + G
Sbjct: 579 RGGSGGSHGGGSGFGGESGGSYGGGEEASG 608
Score = 71.6 bits (174), Expect = 1e-12
Identities = 56/154 (36%), Positives = 65/154 (42%), Gaps = 25/154 (16%)
Query: 195 QGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG----SSNSGGGSGS 250
+ G GG G+ GS+R+S + G GGG SS GGGS
Sbjct: 13 RSGGGGGGGLGSG----------GSIRSSYSRFSSSG---GGGGGGRFSSSSGYGGGSSR 59
Query: 251 QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGS------SGGSSGNSGGSRG--DSGS 302
G G GS G + G S GG S+ S GG GGS SGG +SGG G GS
Sbjct: 60 VCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGS 119
Query: 303 ESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNE 336
+G GS G GG GGG G G NE
Sbjct: 120 GGGFGGGYGSGFGGFGGFGGGAGGGDGGILTANE 153
Score = 68.9 bits (167), Expect = 8e-12
Identities = 52/124 (41%), Positives = 53/124 (42%), Gaps = 12/124 (9%)
Query: 236 GSGGG---------SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSS 286
GSGG SS GGG G S SSG G G GGS S GGS GG S
Sbjct: 23 GSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFS 82
Query: 287 GGSSGN--SGGSRGDSG-SESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGES 343
S G GGSRG G S + SS G G GGSGGG G G G G G
Sbjct: 83 ASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAG 142
Query: 344 GIQG 347
G G
Sbjct: 143 GGDG 146
Score = 67.0 bits (162), Expect = 3e-11
Identities = 51/130 (39%), Positives = 58/130 (44%), Gaps = 7/130 (5%)
Query: 251 QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSG--GSSGNSGGSRGDSGSESSWGS 308
+ G S+G G G S GS GS GGS G G G+ GG G SGS G
Sbjct: 459 EGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGG 518
Query: 309 STGSSSGNHGGSGGGNGHKPGCEKPGNEARG-SGESG--IQGFRGQGVSSNMREISKEGN 365
S G SG+ GGSGGG G G G G SG SG G G G S G+
Sbjct: 519 SYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGS 578
Query: 366 RLLGGSGDNY 375
R GGSG ++
Sbjct: 579 R--GGSGGSH 586
Score = 60.5 bits (145), Expect = 3e-09
Identities = 53/129 (41%), Positives = 56/129 (43%), Gaps = 20/129 (15%)
Query: 242 SNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSG--SSSGGSSGGSS-------GGSSGN 292
S SGGG G GS GS + + SS GG G SSS G GGSS GGS G
Sbjct: 12 SRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGY 71
Query: 293 S--GGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSG-------ES 343
S GGS G + S G G S G G SGGG G G GSG S
Sbjct: 72 SYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGF--GGGFGGGSGGGFGGGYGS 129
Query: 344 GIQGFRGQG 352
G GF G G
Sbjct: 130 GFGGFGGFG 138
Score = 55.5 bits (132), Expect = 9e-08
Identities = 50/171 (29%), Positives = 60/171 (35%), Gaps = 50/171 (29%)
Query: 127 AVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQ-----GQGNPGGLGTPWVHGYPGNSA 181
++R S+ G GG G F S G GG G+G G G + Y G S
Sbjct: 27 SIRSSYSRFSSSGGG----GGGGRFSSSSGYGGGSSRVCGRGGGGSFG----YSYGGGSG 78
Query: 182 GSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS 241
G F + G +G G G FG SGGG
Sbjct: 79 GGFSASSLGGGFGGGSRG----FG-----------------------------GASGGGY 105
Query: 242 SNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGN 292
S+SGG G G SG G G G SG G GG+ GG G + N
Sbjct: 106 SSSGGFGGGFGGGSGGGFGG----GYGSGFGGFGGFGGGAGGGDGGILTAN 152
Score = 49.7 bits (117), Expect = 5e-06
Identities = 43/124 (34%), Positives = 45/124 (36%), Gaps = 7/124 (5%)
Query: 252 SGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311
S S S S G G SGGS S S SS G GG S S GS G G
Sbjct: 7 SSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGG 66
Query: 312 SSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGS 371
S G G G G G G G G G G G G SS+ G GGS
Sbjct: 67 GSFGYSYGGGSGGGFSASSLGGG---FGGGSRGFGGASGGGYSSS----GGFGGGFGGGS 119
Query: 372 GDNY 375
G +
Sbjct: 120 GGGF 123
Score = 48.1 bits (113), Expect = 1e-05
Identities = 42/116 (36%), Positives = 48/116 (41%), Gaps = 11/116 (9%)
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSS--GGSSGNSGGS-----RGDS 300
S S SG G G +G S S S SS G GG SSG GGS RG
Sbjct: 7 SSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGG 66
Query: 301 GSES-SWGSSTG---SSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQG 352
GS S+G +G S+S GG GGG+ G G + G G G G G
Sbjct: 67 GSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGG 122
Score = 37.0 bits (84), Expect = 0.033
Identities = 36/132 (27%), Positives = 51/132 (38%), Gaps = 3/132 (2%)
Query: 40 GHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRV 99
G G G ++ + GG G + S + G G + G FG + G+
Sbjct: 21 GLGSGGSIRSSYSR-FSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGG 79
Query: 100 GEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGI-FGSQGGLG 158
G +A +LG G G + G + G + G G GG+G FG GG G
Sbjct: 80 GFSASSLGG-GFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFG 138
Query: 159 GQGQGNPGGLGT 170
G G GG+ T
Sbjct: 139 GGAGGGDGGILT 150
Score = 37.0 bits (84), Expect = 0.033
Identities = 37/141 (26%), Positives = 45/141 (31%), Gaps = 17/141 (12%)
Query: 19 GEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREA 78
G G G G G G G + G G G G GS + G G +
Sbjct: 492 GSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHS 551
Query: 79 VGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGH 138
G+G G G+ G G G +G R G+ G G G
Sbjct: 552 GGSGGNYGGGSGSGGGSGGGYG------GGSGS----------RGGSGGSHGGGSGFGGE 595
Query: 139 NGAWETSGGHGIFGSQGGLGG 159
+G GG GS GG GG
Sbjct: 596 SGG-SYGGGEEASGSGGGYGG 615
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 103 bits (258), Expect = 2e-22
Identities = 108/372 (29%), Positives = 147/372 (39%), Gaps = 40/372 (10%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG--KAIGKEAG----GAAGSKVSE 69
GSG G +G+ + G HG G S G G + G+ +G G+ S
Sbjct: 897 GSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSS 956
Query: 70 ALGQGTREAVGTGVRQV-PGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHGA 125
G+R + Q G++ + G + +LG+ H G + RHG+
Sbjct: 957 YEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGS 1016
Query: 126 DAVRGSWQGVPGHNGAWETSGGHGIFGS--QGGLG------GQGQG---NPGGLGTPWVH 174
+ + S G W +S G GS GLG GQ G + G H
Sbjct: 1017 GSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTH 1076
Query: 175 GYPGNSAG-SFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE---GCT 230
G G+++G S GA GQ + G G++ + G GS ++ + G
Sbjct: 1077 GQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR 1136
Query: 231 NPPP---SGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSG-GSS 286
P GSG G S+S G GS G S + ++++G SS S GS SG SSG G
Sbjct: 1137 QSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQH 1196
Query: 287 GGSSGNS------GGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGS 340
G SG S G S G S GS + SSG HG G G+GH P G G
Sbjct: 1197 GSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSG-HGRQGSGSGHSP---SRGRHGSGL 1252
Query: 341 GESGIQGFRGQG 352
G S G G G
Sbjct: 1253 GHSSSHGQHGSG 1264
Score = 103 bits (257), Expect = 3e-22
Identities = 106/379 (27%), Positives = 143/379 (37%), Gaps = 53/379 (13%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG-------KAIGKEAGGAAGSKVS 68
GSG G+ +G+ + G HG G S G G ++ G G+ S
Sbjct: 1836 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSS 1895
Query: 69 EALGQGTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHG 124
G+R + G + G++ + G + +LG+ H G + RHG
Sbjct: 1896 SYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 1955
Query: 125 ADAVRGSWQGVPGHNGAWETSGGHGIFGS--QGGLG------------GQGQGNPGGLGT 170
+ + + S G G W +S G GS GLG GQ + G T
Sbjct: 1956 SGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSST 2015
Query: 171 PWVHGYPGNSAGSFGMNP----QGAPWGQGGNGGPPNFGTNTQGAVA--QPGYGSVRASN 224
HG + S G + Q + GQ G+G + G QG+ + PG+G + +
Sbjct: 2016 HGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2075
Query: 225 QNEGCTNPPPSGSGGGSSNSGGGSG-----------SQSGSSGSGSNGDNNNGSSSGGSS 273
+ SGSG SS+ G G S SG S S S + +G SSG
Sbjct: 2076 RQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 2135
Query: 274 SGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKP 333
GS SG SS G GSS S G GS S S HG G G+GH P
Sbjct: 2136 HGSRSGQSSRGERHGSSSGSSSRYGQHGSGS-------RQSSGHGRQGSGSGHSP---SR 2185
Query: 334 GNEARGSGESGIQGFRGQG 352
G GSG S G G G
Sbjct: 2186 GRHGSGSGHSSSHGQHGSG 2204
Score = 103 bits (256), Expect = 4e-22
Identities = 109/373 (29%), Positives = 148/373 (39%), Gaps = 41/373 (10%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG-------KAIGKEAGGAAGSKVS 68
GSG G+ +G+ + G HG G S G G ++ G G+ S
Sbjct: 1366 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSS 1425
Query: 69 EALGQGTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHG 124
G+R + G R G++ + G + +LG+ H G + RHG
Sbjct: 1426 SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 1485
Query: 125 ADAVRGSWQGVPGHNGAWETSGGHGIFGSQ--GGLG------GQGQG---NPGGLGTPWV 173
+ + + S G W +S G GS GLG GQ G + G
Sbjct: 1486 SGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSST 1545
Query: 174 HGYPGNSAG-SFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE---GC 229
HG G+++G S GA GQ + G G++ + G GS ++ + G
Sbjct: 1546 HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 1605
Query: 230 TNPPP---SGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSG-GS 285
P GSG G S+S G GS G S + ++++G SS S GS SG SSG G
Sbjct: 1606 RQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 1665
Query: 286 SGGSSGNSG-GSRGDSGSESS-----WGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARG 339
G SG S G R S S SS GS + SSG HG G G+G P G G
Sbjct: 1666 HGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSG-HGRQGSGSGQSP---SRGRHGSG 1721
Query: 340 SGESGIQGFRGQG 352
G S G G G
Sbjct: 1722 LGHSSSHGQHGSG 1734
Score = 100 bits (248), Expect = 3e-21
Identities = 114/408 (27%), Positives = 161/408 (39%), Gaps = 52/408 (12%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG---------KAIGKEAGGAAGSK 66
GSG G +G + G HG G S G G+ G+ S
Sbjct: 1706 GSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 1765
Query: 67 VSEALGQGTREAVGTGVRQVPGFGAA--DALGNRVGEAA----HALGNT-GHEIGRQAED 119
G G+ G ++ D G+ G+++ H G++ G+Q
Sbjct: 1766 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSG 1825
Query: 120 VIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG----TPWVH- 174
G RG GH+ ++ G + S G G G G G G + W
Sbjct: 1826 ---SGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 1882
Query: 175 GYPGNSAGS---FGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT- 230
GY + +GS G+ GQ G + + + Q G GS ++ + +
Sbjct: 1883 GYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 1942
Query: 231 ---NPPPS----GSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSG----GSSSGSSSG 279
+P PS GSG G S+S G GS SG S S ++ +G SSG S SG SSG
Sbjct: 1943 SGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2002
Query: 280 -GSSGGSSGGSS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNE 336
G G SSG SS G G + G S S G+S+G SS +HG G G+ G G +
Sbjct: 2003 YGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSS-SHGQHGSGSSQSSGY---GRQ 2058
Query: 337 ARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRNSETSPGM 384
GSG+S G RG G S + G+ GSG + + + PG+
Sbjct: 2059 GSGSGQSPGHGQRGSG-SRQSPSYGRHGS----GSGRSSSSGQHGPGL 2101
Score = 99.4 bits (246), Expect = 5e-21
Identities = 105/379 (27%), Positives = 141/379 (37%), Gaps = 53/379 (13%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG-------KAIGKEAGGAAGSKVS 68
GSG G+ +G+ + G HG G S G G ++ G G+ S
Sbjct: 2306 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSS 2365
Query: 69 EALGQGTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHG 124
G+R + G R G++ + G + +LG+ H G + RHG
Sbjct: 2366 SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 2425
Query: 125 ADAVRGSWQGVPGHNGAWETSGGHGIFGS--QGGLG------------GQGQGNPGGLGT 170
+ + + S G W +S G GS GLG GQ + G T
Sbjct: 2426 SGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSST 2485
Query: 171 PWVHGYPGNSAGSFGMNP----QGAPWGQGGNGGPPNFGTNTQGAVA--QPGYGSVRASN 224
HG + S G + Q + GQ G+G + G QG+ + PG+G + +
Sbjct: 2486 HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2545
Query: 225 QNEGCTNPPPSGSGGGSSNSGGGSG-----------SQSGSSGSGSNGDNNNGSSSGGSS 273
+ SGSG SS+ GSG S SG S S S + +G SSG
Sbjct: 2546 RQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 2605
Query: 274 SGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKP 333
GS SG SS G GSS S G GS S S HG G G+G P
Sbjct: 2606 HGSRSGQSSRGERHGSSSGSSSHYGQHGSGS-------RQSSGHGRQGSGSGQSP---SR 2655
Query: 334 GNEARGSGESGIQGFRGQG 352
G G G S G G G
Sbjct: 2656 GRHGSGLGHSSSHGQHGSG 2674
Score = 98.6 bits (244), Expect = 9e-21
Identities = 108/399 (27%), Positives = 155/399 (38%), Gaps = 74/399 (18%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGK---------AIGKEAGGAAGSK 66
GSG G+ + + + G HG S G+ G+ + G+ S
Sbjct: 365 GSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSP 424
Query: 67 VSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQ-AEDVIRHGA 125
G G+ ++ +G + GFG + + G V + ++ G HE + + +HG+
Sbjct: 425 GHGQRGSGSGQSPSSG-QHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGS 483
Query: 126 DAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN-SAGSF 184
+ GH S GHG GS+ G +G+ G+ +G G+ S S
Sbjct: 484 GS---------GH------SSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSL 528
Query: 185 GMNPQGAPWGQGGNG--GPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS- 241
G + G+ GQ + G G+ + GYGS R+S++ P SGSG S
Sbjct: 529 GHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRG-----PYESGSGHSSG 583
Query: 242 -----SNSGGGSG-SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGG 295
S SG SG Q GSS S+ +GS+SG SSS G +SG SS SG
Sbjct: 584 LGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGS 643
Query: 296 SR------------------------------GDSGSESSWGSSTGSSSGNHGGSGGGNG 325
S+ G GS S W SS G G+ G G G
Sbjct: 644 SQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNG-PHGSVSGQSSGFG 702
Query: 326 HKPGC-EKPGNEARGSGESGIQGFRGQGVSSNMREISKE 363
HK G + G GSG S G+R G S S++
Sbjct: 703 HKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQ 741
Score = 97.8 bits (242), Expect = 2e-20
Identities = 113/411 (27%), Positives = 156/411 (37%), Gaps = 61/411 (14%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGH---GLGDALSEGV---GKAIG-KEAGGAAGSKVSE 69
GS G+ +GT+ + GH G G A G G G + G A+G S+
Sbjct: 782 GSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQ 841
Query: 70 ALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-------------- 115
T + + G + + G + HA G H G
Sbjct: 842 GRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSG 901
Query: 116 QAEDVIRHGADAVRGSWQGVPGHNGAWETSGGH-GIFGSQGGLGGQGQGN---------- 164
Q+ RHG+ + R S G G + GH G G G G+
Sbjct: 902 QSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHG 961
Query: 165 --PGGLGTPWVHGYPGNSAGSFGMNPQGAPW----GQGGNGG----PPNFGTNTQGAVAQ 214
G HG S+ S+G + G+ GQ G+G P+ G + G+
Sbjct: 962 SRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQS 1021
Query: 215 PGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSS 274
YG R+ + P SGSG S G G + SG S+G +GSSSG SS+
Sbjct: 1022 SSYGPYRSGSGWSSSRGPYESGSGHSS-----GLGHRESRSGQ-SSGYGQHGSSSGHSST 1075
Query: 275 GSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPG 334
G +SG SS S G G S G S S GS + SSG +G G G+G + PG
Sbjct: 1076 HGQHGSTSGQSS--SCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSGSG-----QSPG 1127
Query: 335 NEARGSG--ESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRNSETSPG 383
+ RGSG +S G G G S + G+ L G + + E+S G
Sbjct: 1128 HGQRGSGSRQSPSYGRHGSG-SGRSSSSGQHGSGL--GESSGFGHHESSSG 1175
Score = 97.1 bits (240), Expect = 3e-20
Identities = 109/370 (29%), Positives = 154/370 (41%), Gaps = 38/370 (10%)
Query: 26 SGEEST----GTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVG 80
SG+ S+ G + G++ HG G S+ G G++ G+ S G G+R++
Sbjct: 2493 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG--YGRQGSGSGQSPGHGQRGSGSRQSPS 2550
Query: 81 TGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-QAEDVIRHGADAVRGSWQGVPGHN 139
G R G G + + G + G HE Q+ +HG+ + GH
Sbjct: 2551 YG-RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGS---------GH- 2599
Query: 140 GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN-SAGSFGMNPQGAPWGQGGN 198
S G+G GS+ G +G+ + G+ +G G+ S S G QG+ GQ +
Sbjct: 2600 -----SSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPS 2654
Query: 199 GGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSG 258
G G + Q G GS R+S++ + S S G SG G S GSG
Sbjct: 2655 RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHS-SVFGQHESGSGHSSAYSQHGSG 2713
Query: 259 SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSG--- 315
S + G GS+SG SS GSS G S +S G RG S+SS G+ SG
Sbjct: 2714 SGHFCSQGQH--GSTSGQSSTFDQEGSSTGQS-SSYGHRGSGSSQSSGYGRHGAGSGQSL 2770
Query: 316 NHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNY 375
+HG G G+G G GSG+S G G + K G+ GGS +Y
Sbjct: 2771 SHGRHGSGSGQS---SSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGSSGSY 2827
Query: 376 ---RNSETSP 382
S TSP
Sbjct: 2828 FLSFPSSTSP 2837
Score = 95.9 bits (237), Expect = 6e-20
Identities = 117/419 (27%), Positives = 165/419 (39%), Gaps = 61/419 (14%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG---------KAIGKEAGGAAGSK 66
GSG G +G + G HG G S G G+ G+ S
Sbjct: 1236 GSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 1295
Query: 67 VSEALGQGTREAVGTGVRQVPGFGAA--DALGNRVGEAAHALGNTGHEIGRQAEDVIRHG 124
G G+ G ++ D G+ G+++ + G+ G Q+ RHG
Sbjct: 1296 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS-SYGHRGSG-SSQSSGYGRHG 1353
Query: 125 ADA----VRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG----TPWVHG- 175
A + RG GH+ ++ G + S G G G G G G + W
Sbjct: 1354 AGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG 1413
Query: 176 ---YPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT-- 230
+ S S G+ GQ G + + + Q G GS ++ + +
Sbjct: 1414 CTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 1473
Query: 231 --NPPPS----GSGGGSSNS----GGGSG-------SQSGSSGSGSNG--DNNNGSSSGG 271
+P PS GSG G S+S G GSG +SGSS S G ++ +G SSG
Sbjct: 1474 GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGY 1533
Query: 272 SSSGSSSGGSS-----GGSSGGSS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGN 324
GSSSG SS G +SG SS G G S G S S GS + SSG +G G G+
Sbjct: 1534 GQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSGS 1592
Query: 325 GHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRNSETSPG 383
G PG + G+ +R S G G G G SS+ + G+ L G + + E+S G
Sbjct: 1593 GQSPGHGQRGSGSRQSPSYGRHG-SGSGRSSSS---GQHGSGL--GESSGFGHHESSSG 1645
Score = 95.5 bits (236), Expect = 8e-20
Identities = 119/395 (30%), Positives = 156/395 (39%), Gaps = 38/395 (9%)
Query: 17 GSGEA-GPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGG----AAGSKVSEAL 71
GSG + G Q G S ++ GE G G + S G + +++ G +GS S +
Sbjct: 484 GSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSP 543
Query: 72 GQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS 131
+G E+ G RQ +G R +GH G ++ R G + G
Sbjct: 544 SRGRHES---GSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQES-RSGQSSGYGQ 599
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGA 191
GH+ T G HG Q GQ G + HG + + +G QG+
Sbjct: 600 HGSSSGHSS---THGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQ--QGS 654
Query: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG-S 250
GQ + G + Q G GS +S+ + S G S SG SG S
Sbjct: 655 GSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYS 714
Query: 251 QSGSSGSGSNGDNNNGSSSG--------GSSSG-SSSGGSSGGSSGGSSGN--SGGSRGD 299
Q GS S S+G +GS SG GSSSG SSS G G S SSG+ G G
Sbjct: 715 QHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGH 774
Query: 300 SGSESSWGSSTGSSSGNHGGSGGGNGHKPGC---EKPGNEARGSG--ESGI-QGFRGQG- 352
S S GSS+G SS +HG G G C E +A G G ESG QG+ G
Sbjct: 775 SPSRVRHGSSSGHSS-SHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGS 833
Query: 353 ----VSSNMREISKEGNRLLGGSGDNYRNSETSPG 383
SS R S G G D+ +S G
Sbjct: 834 ASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYG 868
Score = 95.5 bits (236), Expect = 8e-20
Identities = 105/371 (28%), Positives = 152/371 (40%), Gaps = 55/371 (14%)
Query: 26 SGEEST----GTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVG 80
SG+ ST G++ G++ HG G S+ + G++ G+ S G G+ +
Sbjct: 1787 SGQSSTFDQEGSSTGQSSSHGQHGSGSSQS--SSYGQQGSGSGQSPSRGRHGSGSGHSSS 1844
Query: 81 TGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-QAEDVIRHGADAVRGSWQGVPGHN 139
G + G G + + G + + G HE Q+ +HG+ + GH+
Sbjct: 1845 YG-QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGS---------GHS 1894
Query: 140 GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNG 199
++E G S+G G G+ G HG S S G G+ GQ +
Sbjct: 1895 SSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQ---HG--SGSRQSLGHGQHGSGSGQSPS- 1948
Query: 200 GPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGS 259
P+ G + G+ YG P GSG G S+S G S SG S
Sbjct: 1949 --PSRGRHGSGSGQSSSYG---------------PYGSGSGWSSSRGPYESGSGHSSGLG 1991
Query: 260 NGDNNNGSSSGGSSSGSSSGGSS-----GGSSGGSS--GNSGGSRGDSGSESSWGSSTGS 312
+ ++ +G SSG GSSSG SS G +SG SS G G S G S S GS +
Sbjct: 1992 HRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQ 2051
Query: 313 SSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSG 372
SSG +G G G+G + PG+ RGSG + G S S + LG S
Sbjct: 2052 SSG-YGRQGSGSG-----QSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGES- 2104
Query: 373 DNYRNSETSPG 383
+ + E+S G
Sbjct: 2105 SGFGHHESSSG 2115
Score = 95.5 bits (236), Expect = 8e-20
Identities = 99/353 (28%), Positives = 136/353 (38%), Gaps = 40/353 (11%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75
GS G+ +G+ ++LGHG G + + G+ G+ S G G+
Sbjct: 1914 GSSSGSSSSYGQHGSGSR--QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGS 1971
Query: 76 REAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGV 135
+ G + G G + LG+R + + G H G + HG
Sbjct: 1972 GWSSSRGPYE-SGSGHSSGLGHRESRSGQSSGYGQH--GSSSGHSSTHGQHGSASGQSSS 2028
Query: 136 PGHNGAWE-TSGGHGIFGS----QGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQG 190
G +GA S HG GS G G QG G+ G HG G+ + Q
Sbjct: 2029 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG----HGQRGSGSR------QS 2078
Query: 191 APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPS----GSGGGSSNSGG 246
+G+ G+G + + G PG G +E + S GSG G S+ G
Sbjct: 2079 PSYGRHGSGSGRSSSSGQHG----PGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYG 2134
Query: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306
GS+SG S G +++GSSS GS S SSG GS SRG GS
Sbjct: 2135 QHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGS---- 2190
Query: 307 GSSTGSSSGNHG-GSGGGNGHKPGCEKPGNEA------RGSGESGIQGFRGQG 352
GS SS G HG GSG + P + G+ + GSG S G G
Sbjct: 2191 GSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSG 2243
Score = 95.1 bits (235), Expect = 1e-19
Identities = 115/420 (27%), Positives = 164/420 (39%), Gaps = 63/420 (15%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG---------KAIGKEAGGAAGSK 66
GSG G +G+ + G HG G S G G+ G+ S
Sbjct: 2176 GSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 2235
Query: 67 VSEALGQGTREAVGTGVRQVPGFGAA--DALGNRVGEAA----HALGNT-GHEIGRQAED 119
G G+ G ++ D G+ G+++ H G++ G+Q
Sbjct: 2236 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSG 2295
Query: 120 VIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG----TPWVH- 174
G RG GH+ ++ G + S G G G G G G + W
Sbjct: 2296 ---SGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 2352
Query: 175 GYPGNSAGS---FGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT- 230
GY + +GS G+ GQ G + + + Q G GS ++ + +
Sbjct: 2353 GYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 2412
Query: 231 ---NPPPS----GSGGGSSNS----GGGSG---------SQSGSSGSGSNGDNNNGSSSG 270
+P PS GSG G S+S G GSG S SG S + ++ +G SSG
Sbjct: 2413 SGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2472
Query: 271 GSSSGSSSGGSS-----GGSSGGSS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGG 323
GSSSG SS G +SG SS G G S G S S GS + SSG +G G G
Sbjct: 2473 YGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSG 2531
Query: 324 NGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRNSETSPG 383
+G PG + G+ +R S G G G G SS+ + G+ L G + + E+S G
Sbjct: 2532 SGQSPGHGQRGSGSRQSPSYGRHG-SGSGRSSSS---GQHGSGL--GESSGFGHHESSSG 2585
Score = 91.7 bits (226), Expect = 1e-18
Identities = 97/351 (27%), Positives = 136/351 (38%), Gaps = 36/351 (10%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75
GS G+ +G+ ++LGHG G + + G+ G+ S G G+
Sbjct: 2384 GSSSGSSSSYGQHGSGSR--QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGS 2441
Query: 76 REAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGV 135
+ G + G G + LG+R + + G H G + HG
Sbjct: 2442 GWSSSRGPYE-SGSGHSSGLGHRESRSGQSSGYGQH--GSSSGHSSTHGQHGSTSGQSSS 2498
Query: 136 PGHNGAWE-TSGGHGIFGS----QGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQG 190
G +GA S HG GS G G QG G+ G HG G+ + Q
Sbjct: 2499 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG----HGQRGSGSR------QS 2548
Query: 191 APWGQGGNGG--PPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGS 248
+G+ G+G + G + G G+G +S+ + GSG G S+ G
Sbjct: 2549 PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ--HGSGSGHSSGYGQH 2606
Query: 249 GSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGS 308
GS+SG S G +++GSSS GS S SSG GS SRG GS G
Sbjct: 2607 GSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGS----GL 2662
Query: 309 STGSSSGNHG-GSGGGNGHKPGCEKPGNEA------RGSGESGIQGFRGQG 352
SS G HG GSG + P + G+ + GSG S G G
Sbjct: 2663 GHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSG 2713
Score = 89.0 bits (219), Expect = 7e-18
Identities = 106/403 (26%), Positives = 151/403 (37%), Gaps = 63/403 (15%)
Query: 26 SGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQ 85
SG G+ G++ GHG + S G + G+ G+ S S G G+ ++
Sbjct: 878 SGRGRHGSGSGQSPGHGQRGSGS-GQSPSYGRHGSGSGRSSSSGRHGSGSGQS------- 929
Query: 86 VPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETS 145
GFG + G G H G+ GH + +HG+ + + S G + +S
Sbjct: 930 -SGFGHKSSSGQSSGYTQHGSGS-GHSSSYE-----QHGSRSGQSSRSEQHGSSSGSSSS 982
Query: 146 GGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG---SFGMNPQGAPWG------QG 196
G GS+ LG G+ G G G+ +G S+G G+ W +
Sbjct: 983 YGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYES 1042
Query: 197 GNGGPPNFGTNTQGAVAQPGYGSVRASN--------------QNEGCTNPPPSG------ 236
G+G G + GYG +S+ Q+ C S
Sbjct: 1043 GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH 1102
Query: 237 ----------SGGGSSNSGGGSGSQSGSSGSGSNGD---NNNGSSSGGSSSGSSSGGSSG 283
SG G SG G G GSGS +GS SG SSS G G
Sbjct: 1103 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLG 1162
Query: 284 GSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGES 343
SSG G+ S G S S S GS +G SSG +G G +G E+ G+ + S
Sbjct: 1163 ESSG--FGHHESSSGQSSSYSQHGSGSGHSSG-YGQHGSRSGQSSRGERHGSSSGSSSHY 1219
Query: 344 GIQGFRGQGVSSNMREISKEG---NRLLGGSGDNYRNSETSPG 383
G G + S + R+ S G +R GSG + +S G
Sbjct: 1220 GQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHG 1262
Score = 88.6 bits (218), Expect = 1e-17
Identities = 93/314 (29%), Positives = 123/314 (39%), Gaps = 14/314 (4%)
Query: 19 GEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREA 78
G SG G+ G++ GHG + S + G+ G+ S S G G E+
Sbjct: 2516 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ-SPSYGRHGSGSGRSSSSGQHGSGLGES 2574
Query: 79 VGTGVRQVPGFGAADALGNRVGEAAHALGNTGH-EIGRQAEDVIRHGADAVRGSWQGVPG 137
G G + G + + + H+ G H Q+ RHG+ + S G
Sbjct: 2575 SGFGHHESSS-GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQ-- 2631
Query: 138 HNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG-SFGMNPQGAPWGQG 196
H S GHG GS G + GLG HG G+ +G S P + G
Sbjct: 2632 HGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHS 2691
Query: 197 GNGGPPNFGTNTQGAVAQPGYGSVRASNQNE-GCTNPPPS-----GSGGGSSNSGGGSGS 250
G G+ A +Q G GS +Q + G T+ S GS G S+S G GS
Sbjct: 2692 SVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGS 2751
Query: 251 QSG-SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGG-SRGDSGSESSWGS 308
S SSG G +G + S S G S SS G G SG S G S+ SGS S
Sbjct: 2752 GSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYS 2811
Query: 309 STGSSSGNHGGSGG 322
S + GGS G
Sbjct: 2812 YCKGGSNHDGGSSG 2825
Score = 88.2 bits (217), Expect = 1e-17
Identities = 96/351 (27%), Positives = 135/351 (38%), Gaps = 36/351 (10%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75
GS G+ +G+ ++LGHG G + + G+ G+ S G+
Sbjct: 974 GSSSGSSSSYGQHGSGSR--QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGS 1031
Query: 76 REAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGV 135
+ G + G G + LG+R + + G H G + HG
Sbjct: 1032 GWSSSRGPYE-SGSGHSSGLGHRESRSGQSSGYGQH--GSSSGHSSTHGQHGSTSGQSSS 1088
Query: 136 PGHNGAWE-TSGGHGIFGS----QGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQG 190
G +GA S HG GS G G QG G+ G HG G+ + Q
Sbjct: 1089 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG----HGQRGSGSR------QS 1138
Query: 191 APWGQGGNGG--PPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGS 248
+G+ G+G + G + G G+G +S+ + GSG G S+ G
Sbjct: 1139 PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ--HGSGSGHSSGYGQH 1196
Query: 249 GSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGS 308
GS+SG S G +++GSSS GS S SSG GS SRG GS G
Sbjct: 1197 GSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGS----GL 1252
Query: 309 STGSSSGNHG-GSGGGNGHKPGCEKPGNEA------RGSGESGIQGFRGQG 352
SS G HG GSG + P + G+ + GSG S G G
Sbjct: 1253 GHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSG 1303
Score = 87.8 bits (216), Expect = 2e-17
Identities = 89/328 (27%), Positives = 132/328 (40%), Gaps = 38/328 (11%)
Query: 64 GSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-QAEDVIR 122
G + S++ R G+G Q P +G G+ G+++ N H G Q+ +
Sbjct: 180 GEQNSDSHQSSGRGQCGSGSGQSPNYGQH---GSGSGQSS---SNDTHGSGSGQSSGFSQ 233
Query: 123 HGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG 182
H + + G G H S G+G GS+ G +G+ + G+
Sbjct: 234 HKSSS--GQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGS------------ 279
Query: 183 SFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSS 242
+ +GQ G+G + G QG+ ++ VR + + ++ GSG S
Sbjct: 280 -------SSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYS 332
Query: 243 NSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGS 302
S G S SG + ++ +G SSG S GS SG SS GS+ S G GS
Sbjct: 333 YSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGS 392
Query: 303 ESSWGSSTG---SSSGNHGGSG---GGNGHKPGCEKPGNEARGSGESGIQGFRGQGVS-S 355
S SS G S+S + G G G+G PG G GSG+S G G G S
Sbjct: 393 SSRQSSSYGQHESASRHSSGRGQHSSGSGQSPG---HGQRGSGSGQSPSSGQHGTGFGRS 449
Query: 356 NMREISKEGNRLLGGSGDNYRNSETSPG 383
+ G+ G G + +SE S G
Sbjct: 450 SSSGPYVSGSGYSSGFGHHESSSEHSSG 477
Score = 87.4 bits (215), Expect = 2e-17
Identities = 102/376 (27%), Positives = 141/376 (37%), Gaps = 29/376 (7%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTR 76
GSG L G+ +G+ + G + S G + G G+ S G+
Sbjct: 987 GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS-GQSSSYGPYRSGSGWSSSRGPYESGSG 1045
Query: 77 EAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGH-EIGRQAEDVIRHGADAVRGSWQGV 135
+ G G R+ G + G + H+ + H Q+ +HGA + + S G
Sbjct: 1046 HSSGLGHRESRS-GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQ 1104
Query: 136 PGHNGAWETSGGHGIFGSQGGLG-GQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWG 194
H S G+G GS G G GQ G +P + S S G+ G
Sbjct: 1105 --HGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLG 1162
Query: 195 QGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGS 254
+ G + + +Q G GS +S + GS G S+ G GS SGS
Sbjct: 1163 ESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ-------HGSRSGQSSRGERHGSSSGS 1215
Query: 255 S------GSG---SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESS 305
S GSG S+G GS SG S S G G SS S G G G S S
Sbjct: 1216 SSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSS--SHGQHGSGSGRSSSRGP 1273
Query: 306 WGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGN 365
+ S +G SS G G+GH + G+ GSG QG G S +EG+
Sbjct: 1274 YESRSGHSS-VFGQHESGSGHSSAYSQHGS---GSGHFCSQGQHG-STSGQSSTFDQEGS 1328
Query: 366 RLLGGSGDNYRNSETS 381
S +R S +S
Sbjct: 1329 STGQSSSYGHRGSGSS 1344
Score = 87.0 bits (214), Expect = 3e-17
Identities = 95/351 (27%), Positives = 134/351 (38%), Gaps = 36/351 (10%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75
GS G+ +G+ ++LGHG G + + G+ G+ S G G+
Sbjct: 1444 GSSSGSSSSYGQHGSGSR--QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGS 1501
Query: 76 REAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGV 135
+ G + G + LG+R + + G H G + HG
Sbjct: 1502 GWSSSRGPYE-SGSSHSSGLGHRESRSGQSSGYGQH--GSSSGHSSTHGQHGSTSGQSSS 1558
Query: 136 PGHNGAWE-TSGGHGIFGS----QGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQG 190
G +GA S HG GS G G QG G+ G HG G+ + Q
Sbjct: 1559 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG----HGQRGSGSR------QS 1608
Query: 191 APWGQGGNGG--PPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGS 248
+G+ G+G + G + G G+G +S+ + GSG G S+ G
Sbjct: 1609 PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ--HGSGSGHSSGYGQH 1666
Query: 249 GSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGS 308
GS+SG S G +++ SSS GS S SSG GS SRG GS G
Sbjct: 1667 GSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGS----GL 1722
Query: 309 STGSSSGNHG-GSGGGNGHKPGCEKPGNEA------RGSGESGIQGFRGQG 352
SS G HG GSG + P + G+ + GSG S G G
Sbjct: 1723 GHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSG 1773
Score = 86.7 bits (213), Expect = 4e-17
Identities = 96/369 (26%), Positives = 138/369 (37%), Gaps = 42/369 (11%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTR 76
GSG + + G++ +G+ + G D G + G+ G+ S + G +
Sbjct: 640 GSGSSQSSRYGQQGSGSGQSPSRGRHGSDF---GHSSSYGQHGSGSGWSSSNGPHGSVSG 696
Query: 77 EAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVP 136
++ GFG G G + H G++ H G + +HG+ + + S
Sbjct: 697 QS--------SGFGHKSGSGQSSGYSQHGSGSS-HSSGYR-----KHGSRSGQSSRSEQH 742
Query: 137 GHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWV-HGYPGNSAGSFGMNPQGAPWG- 194
G + +S G GS G QG+ G V HG + S G + G
Sbjct: 743 GSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSS 802
Query: 195 -----QGGNGGPPNFGTNTQGA---VAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG 246
+ G+G FG + G+ +Q G S S+Q GS G S+S G
Sbjct: 803 SCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGR-------HGSTSGQSSSSG 855
Query: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306
S SG S S ++ + +SG GS SG S G GS S G GS
Sbjct: 856 QHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGS---- 911
Query: 307 GSSTGSSSGNHG---GSGGGNGHKPGC-EKPGNEARGSGESGIQGFRGQGVSSNMREISK 362
GS SSSG HG G G GHK + G GSG + G S S+
Sbjct: 912 GSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSE 971
Query: 363 EGNRLLGGS 371
+ G S
Sbjct: 972 QHGSSSGSS 980
Score = 74.3 bits (181), Expect = 2e-13
Identities = 95/361 (26%), Positives = 143/361 (39%), Gaps = 68/361 (18%)
Query: 56 GKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR 115
G+ G+ S ++ G G+ ++ G + + G G + H G+ GH G
Sbjct: 206 GQHGSGSGQSSSNDTHGSGSGQSSGFSQHK-------SSSGQSSGYSQHGSGS-GHSSGY 257
Query: 116 QAEDVIRHGADAVRGS-WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWV- 173
+HG+ + + S + +G+ + G HG GS+ LG QG+ V
Sbjct: 258 G-----QHGSRSGQSSRGERHRSSSGSSSSYGQHGS-GSRQSLGHGRQGSGSRQSPSHVR 311
Query: 174 HGYPGNSAGSFGMNPQGAPWG------QGGNGGPPNFGTNTQGAVAQPGY-----GSVRA 222
HG + S G + G+ + + G+G FG + G+ GY GS +
Sbjct: 312 HGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHS 371
Query: 223 SNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSS 282
S+Q + GS G ++S G GS S S S ++ + SSG S SG S
Sbjct: 372 SSQGQ-------HGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSP 424
Query: 283 G-GSSGGSSGNS------GGSRGDSGSESSWGSSTGSSSG---------------NHG-G 319
G G G SG S G G S S + S +G SSG HG G
Sbjct: 425 GHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSG 484
Query: 320 SGGGNGHKPGCEKPGNEARG------SGESGIQGFRGQGVSSNMREISKEGNRLLGGSGD 373
SG +GH + G +RG +G S G G G ++ S+ G+ GSG
Sbjct: 485 SGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGH-SRHGS----GSGQ 539
Query: 374 N 374
+
Sbjct: 540 S 540
Score = 56.2 bits (134), Expect = 5e-08
Identities = 56/193 (29%), Positives = 79/193 (40%), Gaps = 20/193 (10%)
Query: 193 WGQGGNGGPPNFGTNTQGAVAQPGYGSV--RASNQNEGCTNPPPSGSGGGSSNSGGGSGS 250
W G N ++ N +G++ +PG S+ R S Q + G NS G S
Sbjct: 132 WSAGEND---SYSRNVRGSL-KPGTESISRRLSFQRDF----------SGQHNSYSGQSS 177
Query: 251 QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGS-RGDSGSESSWGSS 309
G S S+ + G GS + G GS SS ++ GS G S S SS
Sbjct: 178 SYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSS 237
Query: 310 TGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLG 369
+G SSG + G G+GH G + G+ + G G + G SS+ + G+R
Sbjct: 238 SGQSSG-YSQHGSGSGHSSGYGQHGSRS-GQSSRGERHRSSSGSSSSYGQ-HGSGSRQSL 294
Query: 370 GSGDNYRNSETSP 382
G G S SP
Sbjct: 295 GHGRQGSGSRQSP 307
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 93.6 bits (231), Expect = 3e-19
Identities = 109/394 (27%), Positives = 149/394 (37%), Gaps = 64/394 (16%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGKAIGKE---AGGAAGSKVSEALG 72
GSG + G+ +G+ G HG G S G G+ + + G GS S++ G
Sbjct: 798 GSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSG 857
Query: 73 QGTREAVGTGVRQVPGFGA-ADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS 131
G G+ Q GFG + G G H G+ Q+ +HG + G
Sbjct: 858 YGQH---GSSSGQTSGFGQHRSSSGQYSGFGQHGSGSG------QSSGFGQHGTGS--GQ 906
Query: 132 WQGVPGHNGAWETS--GGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQ 189
+ G H S G HG SQ G GQ HG FG +
Sbjct: 907 YSGFGQHESRSHQSSYGQHGSGSSQSS--GYGQ-----------HGSSSGQTFGFGQHRS 953
Query: 190 GAPWGQG------GNGGPPNFGTNTQGAVAQPGYGS--VRASNQNEGCTNPPPSGSGGGS 241
G+ G G+G FG + G+ G+G R+S N G GSG
Sbjct: 954 GSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYG-----QHGSGSSQ 1008
Query: 242 SNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSG-GSSGGSSGNSGG----- 295
S+ G GS SG + +++G SG GS S SSG G G SG S G
Sbjct: 1009 SSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYE 1068
Query: 296 --SRGDSGSESSWGSSTGSSSGNHGGSGGGNG----HKPGCEKPGNEARGSGESGIQGFR 349
SR S + GSS S G HG + G H+PG ++ G G+ G
Sbjct: 1069 SRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPG----SGQSSGFGQYG----S 1120
Query: 350 GQGVSSNMREISKEGNRLLGGSGDNYRNSETSPG 383
G G SS + + G + YR+ ++S G
Sbjct: 1121 GSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYG 1154
Score = 90.1 bits (222), Expect = 3e-18
Identities = 121/443 (27%), Positives = 163/443 (36%), Gaps = 91/443 (20%)
Query: 16 LGSGEAGPLQSGEESTGTNIGEALG---HGLGDALSEGVGK--------AIGKEAGGAA- 63
LGSG++ +G G+ G++ G HG G S G G+ + G+ + G++
Sbjct: 572 LGSGQS----TGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQ 627
Query: 64 -------GSKVSEALGQ-GTREAVGTGVRQV-PGFGAADALGNRVGEAAHALGNTGHEIG 114
GS+ + GQ G+ + TG Q G G + G V + + G HE
Sbjct: 628 SSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESR 687
Query: 115 RQAEDVIRHGADAVRGSWQGVPGHN-GAWETSGGHGIFGSQG---GLGGQGQGNPGGLGT 170
+HG + + S G G + G G H + Q G G G G G G
Sbjct: 688 SGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQ 747
Query: 171 PWVHGYPGNSAGSFGMNP----------------QGAPWGQGGNGGPPNFGTNTQGAVAQ 214
HG + FG + Q + +GQ G+ FG + G+
Sbjct: 748 ---HGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQS 804
Query: 215 PGYGSVRASNQNEGCTNPPPSGSGGGS------SNSGGGSGSQSGSSGSGSNGDNNNGSS 268
G+G + + SGSG S S S S Q GS S S+G +GSS
Sbjct: 805 TGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSS 864
Query: 269 SGGSSS-----------------GSSSGGSSG-GSSGGSSGNSGG-------SRGDSGSE 303
SG +S GS SG SSG G G SG G S S +
Sbjct: 865 SGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQ 924
Query: 304 SSWGSSTGSSSGNHGGSGG---GNG-HKPGC-EKPGNEARGSGESGIQGF----RGQGVS 354
GSS S G HG S G G G H+ G + G GSG GF G G S
Sbjct: 925 HGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKS 984
Query: 355 SNM---REISKEGNRLLGGSGDN 374
S S + N GSG +
Sbjct: 985 SGFGQHESRSSQSNYGQHGSGSS 1007
Score = 89.7 bits (221), Expect = 4e-18
Identities = 106/370 (28%), Positives = 150/370 (40%), Gaps = 55/370 (14%)
Query: 26 SGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQ 85
SG G++ G+ G G + LS G + G+ +GS S GQ G+G Q
Sbjct: 704 SGYGQHGSSSGQTSGFGQHE-LSSGQSSSFGQHG---SGSGQSSGFGQH-----GSGSGQ 754
Query: 86 VPGFGAADALGNRVGEAAHALGNT-----GHEIGRQAEDVIRHGADAVRGSWQGVPGHNG 140
GFG ++ + H+ G++ G RQ +HG+ + + + G G +G
Sbjct: 755 SSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYG-SG 813
Query: 141 AWETSGGHGIFGSQGGLGGQGQG-------------NPGGLGTPWVHGYP--GNSAGS-- 183
+ +++G FG G GQ G G G+ GY G+S+G
Sbjct: 814 SGQSAG----FGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTS 869
Query: 184 -FGMNP----QGAPWGQGGNGGPPN--FGTNTQGAVAQPGYG-----SVRASNQNEGCTN 231
FG + Q + +GQ G+G + FG + G+ G+G S ++S G +
Sbjct: 870 GFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGS 929
Query: 232 PPPSGSGGGSSNSGGGSGSQSGSSGSG-SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSS 290
SG G S+SG G SGSG S+G +GS SG SS SG SSG
Sbjct: 930 SQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQ 989
Query: 291 GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGG-----GNGHKPGCEKPGNEARGSGESGI 345
S S+ + G S GSS S G HG S G G + G GSG
Sbjct: 990 HESRSSQSNYGQHGS-GSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQS 1048
Query: 346 QGFRGQGVSS 355
GF G S
Sbjct: 1049 SGFGQHGTGS 1058
Score = 82.8 bits (203), Expect = 5e-16
Identities = 104/380 (27%), Positives = 162/380 (42%), Gaps = 63/380 (16%)
Query: 17 GSGEAGPLQS--GEESTGTNIGEALG-HGLGDALSEGVGK----AIGKEAGGAAGSKVSE 69
G+ E G Q+ G+ TG++ G +G G + S G+ + G+ + ++ ++ S+
Sbjct: 356 GARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEFSK 415
Query: 70 A--LGQGTREAV-----GTGVRQVPGF-----GAADALGNRVGEAAHALGNTGH-EIGRQ 116
G G+ ++ GTG+ Q GF G+ G ++ +LG H +
Sbjct: 416 CDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGK 475
Query: 117 AEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQG-----NPGGLGTP 171
+HG+ + + S G G +G+ ++SG FG G + GQ G + G +
Sbjct: 476 TSGFGQHGSGSGQSSGFGQCG-SGSGQSSG----FGQHGSVSGQSSGFGQHGSVSGQSSG 530
Query: 172 WVHGYPGNSAGSFGMNPQGAP----WGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE 227
+ + S+G + G+ +GQ G+ FG + G+ G+G
Sbjct: 531 FGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQY------- 583
Query: 228 GCTNPPPSGSGGGSSNSGGGSGSQSG-SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSS 286
GSG G S+ G GS SG SSG G + + SS G SSGSS SSG
Sbjct: 584 --------GSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQ--SSGYGQ 633
Query: 287 GGSSGNSGGSRGDSGSESS-----WGSSTGSSSG---NHGGSGGGNGHKPGCEKPGNEA- 337
GS SG + SGS S +GS +G SSG + GSG +G + G+ +
Sbjct: 634 HGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSY 693
Query: 338 --RGSGESGIQGFRGQGVSS 355
G G S G+ G SS
Sbjct: 694 GQHGFGSSQSSGYGQHGSSS 713
Score = 78.6 bits (192), Expect = 1e-14
Identities = 114/426 (26%), Positives = 171/426 (40%), Gaps = 90/426 (21%)
Query: 27 GEESTGTNIGEALG-HGLGDALSEGVGK---AIGKEAG-GAAGSKVSEALGQGTREAVGT 81
G+ +G++ G HG + G G+ + G+ +G G GS ++ G G GT
Sbjct: 846 GQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQH---GT 902
Query: 82 GVRQVPGFGAADALGNRVGEAAHALGNT--------GHEIGR------------QAEDVI 121
G Q GFG ++ ++ H G++ G G+ Q+
Sbjct: 903 GSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFG 962
Query: 122 RHGADAVRGSWQGVPGHNGAWETSG--GHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN 179
+HG+ + + S G +G+ ++SG H SQ G G G+ G +G G+
Sbjct: 963 QHGSGSGQSSGFG-QHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSG----YGQHGS 1017
Query: 180 SAGS---FGMNP----QGAPWGQGGNGGPPN--FGTNTQGAVAQPGYG-----SVRASNQ 225
S+G FG + Q + +GQ G+G + FG + G+ G+G S ++S
Sbjct: 1018 SSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYG 1077
Query: 226 NEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSG-SNGDNNNGSSSGGSSSGSSSGGSSGG 284
G + SG G SNSG SG GSG S+G GS SG SS G +G
Sbjct: 1078 QHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGK 1137
Query: 285 SSG------------------GSSGNSGGSRGDSGS-------ESSWGSSTGSSSGNH-- 317
SSG GSS +SG + +SGS + GS SSSG H
Sbjct: 1138 SSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHIS 1197
Query: 318 --------GGSGGGNGHKPGCEKPGNEARGSGESGIQG----FRGQGVSSNMREISKEGN 365
G G G+G G + ++ SG S + G GQ +++ S +G
Sbjct: 1198 DSGQSTGFGQYGSGSGQSTGLGQGESQQVESG-STVHGRQETTHGQTINTTRHSQSGQGQ 1256
Query: 366 RLLGGS 371
GS
Sbjct: 1257 STQTGS 1262
Score = 73.2 bits (178), Expect = 4e-13
Identities = 91/338 (26%), Positives = 124/338 (36%), Gaps = 40/338 (11%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGK---AIGKEAG------------ 60
GS G+ +G+ G HG G S G G+ GK +G
Sbjct: 939 GSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSN 998
Query: 61 -GAAGSKVSEALGQGTREAVGTGVRQVPGFGA-ADALGNRVGEAAHALGNTGHEIGRQAE 118
G GS S++ G G G+ Q GFG + G G H G+ Q+
Sbjct: 999 YGQHGSGSSQSSGYGQH---GSSSGQTTGFGQHRSSSGQYSGFGQHGSGSD------QSS 1049
Query: 119 DVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPG 178
+HG + + S G + G HG SQ GQ N G H PG
Sbjct: 1050 GFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHR-PG 1108
Query: 179 NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG 238
+ S G G+ GQ G GT AQ Y S ++S G + SG G
Sbjct: 1109 SGQSS-GFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCG 1167
Query: 239 GGSSNSGGGSGSQSGSSGSGSNGDNNNG---SSSGGSSSGSSSGGSSGGSSGGSSGNS-- 293
SG G + G SGS+ +++G S SG S+ G SG S+G G S
Sbjct: 1168 --QHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQ 1225
Query: 294 --GGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPG 329
GS E++ G + ++ H SG G + G
Sbjct: 1226 VESGSTVHGRQETTHGQTINTT--RHSQSGQGQSTQTG 1261
Score = 71.2 bits (173), Expect = 2e-12
Identities = 75/237 (31%), Positives = 90/237 (37%), Gaps = 29/237 (12%)
Query: 140 GAWETSGGHGIFGSQGGLG----GQGQGNPGGLGTPWVHGYPGNSAGSFGM----NPQGA 191
G+ +T G H SQ LG G G G G HG + FG + Q +
Sbjct: 448 GSGQTCGQHESTSSQS-LGYDQHGSSSGKTSGFGQ---HGSGSGQSSGFGQCGSGSGQSS 503
Query: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGS-GGGSSNSGG---- 246
+GQ G+ + G G+V+ G Q+E + G G GSS S G
Sbjct: 504 GFGQHGSVSGQSSGFGQHGSVS----GQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQY 559
Query: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSES-- 304
GS SG G + G GS SG SSG GS G S G SG S
Sbjct: 560 GSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYG 619
Query: 305 --SWGSSTGSSSGNHGG---SGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSN 356
S GSS S G HG SG G + G GSG GF GQ VS +
Sbjct: 620 QHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGF-GQHVSGS 675
Score = 62.4 bits (150), Expect = 7e-10
Identities = 104/398 (26%), Positives = 141/398 (35%), Gaps = 86/398 (21%)
Query: 25 QSGEE---STGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGT 81
+SGEE +G+N E GHG LS G+ + G E+ + LG + +
Sbjct: 218 ESGEEYESGSGSNSWERKGHG---GLSCGL-ETSGHESNSTQSRIREQKLGSSCSGSGDS 273
Query: 82 GVRQ-VPGFGAADALGNRVGEAA----HALGNTGHEI-----GRQAEDVIRHGADAVRGS 131
G R G+ + G ++ H G G++ G Q+ G V G
Sbjct: 274 GRRSHACGYSNSSGCGRPQNASSSCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHGCVSG- 332
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPW-----------VHGYPGNS 180
G P G E++ + SQ G G + G P G W +G G+
Sbjct: 333 --GQPSGCGQPESNPCSQSY-SQRGYGARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQ 389
Query: 181 AGSFGMNPQGAPWGQGGNGGPPN-----------------FGTNTQGAVAQPGY-----G 218
+ S G + G+ G+ N N F + G G+ G
Sbjct: 390 SCSNGQHEYGS-CGRFSNSSSSNEFSKCDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCG 448
Query: 219 SVRASNQNEGCTNPP--------PSGSGGGSSNSGGGSGSQSG----SSGSGSNGDNNNG 266
S + Q+E ++ SG G G GSG SG SGSG +
Sbjct: 449 SGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQH 508
Query: 267 SSSGGSSSGSSSGGSSGGSSGG-------SSGNSGGSRGDSGSESS----WGSSTGSSSG 315
S G SSG GS G S G S +S G G S+SS +GS S G
Sbjct: 509 GSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFG 568
Query: 316 NHG-GSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQG 352
HG GSG G G GSG+S G G G
Sbjct: 569 QHGLGSGQSTGF-------GQYGSGSGQSSGFGQHGSG 599
Score = 57.4 bits (137), Expect = 2e-08
Identities = 95/376 (25%), Positives = 128/376 (34%), Gaps = 72/376 (19%)
Query: 19 GEAGPLQSGEESTGTNIGEALGHG-LGDALSE-GVGKAIGKEAGGAAGSKVSEALGQGTR 76
G +G QS + + T A GH D+ GV A G AGS+ E+ G
Sbjct: 2008 GHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGES-GSSVH 2066
Query: 77 EAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVP 136
E GT G HA G R + R G+ S V
Sbjct: 2067 ERHGT------------THGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEV- 2113
Query: 137 GHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQG 196
H+G T GH ++ G G G GT +HG G++ GQ
Sbjct: 2114 -HSGVSHTHSGHTYGQARSQHGESGSAIHGRQGT--IHGQTGDTTRH----------GQS 2160
Query: 197 GNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSG 256
G+G G+ T G S S+ +E + P+ SG S +G G QSGSSG
Sbjct: 2161 GHGQSTQTGSRTTGRQRS----SHSESSDSEVHSEASPTHSGHTHSQAGSRHG-QSGSSG 2215
Query: 257 SG------------------------SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGN 292
G G G G S S S S GS +
Sbjct: 2216 HGRQGTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESS----DSEVHSWGSHTH 2271
Query: 293 SGGSRGDSGSESSWGSST--GSSSGNHGGSGGGNGHKPGCEKPGNEARG-SGESGIQGFR 349
SG +G +GS+ ST G HG +G H G+ G S ++G + R
Sbjct: 2272 SGHIQGQAGSQQRQPGSTVHGRLETTHGQTGDTTRH-------GHSGYGQSTQTGSRSSR 2324
Query: 350 GQGVSSNMREISKEGN 365
S+ E + G+
Sbjct: 2325 ASHFQSHSSERQRHGS 2340
Score = 56.2 bits (134), Expect = 5e-08
Identities = 92/396 (23%), Positives = 133/396 (33%), Gaps = 59/396 (14%)
Query: 24 LQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGV 83
+Q+G +TG G GV G AGS E+ G E GT
Sbjct: 1941 IQTGSRTTGRR-GSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPES-GSSVHERHGT-- 1996
Query: 84 RQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWE 143
G H G++GH Q + + GH+G
Sbjct: 1997 ----------THGQTADTTRH--GHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSH 2044
Query: 144 TSGGH--GIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSA----GSFGMNPQ--GAPWGQ 195
T GH G GSQ G G G HG G++ G + Q G+
Sbjct: 2045 THSGHAHGQAGSQHGESGSSVHERHGT----THGQTGDTTRHAHSGHGQSTQRGSRTAGR 2100
Query: 196 GGNGGPPNFGTNTQGAVAQPG----YGSVRASNQNEGCTNPPPSGSGGGSSN-------S 244
G+G + + V+ YG R+ + G G+ G + S
Sbjct: 2101 RGSGHSESSDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQS 2160
Query: 245 GGGSGSQSGSSGSGSNGDNNNGSS------------SGGS-SSGSSSGGSSGGSSGGSSG 291
G G +Q+GS +G +++ SS SG + S S G SG S G G
Sbjct: 2161 GHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQG 2220
Query: 292 NSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQG-FRG 350
+ G GD+ + +G + G+ G+GH E +E G G +G
Sbjct: 2221 TTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGHS---ESSDSEVHSWGSHTHSGHIQG 2277
Query: 351 QGVSSNMREISKEGNRL---LGGSGDNYRNSETSPG 383
Q S + S RL G +GD R+ + G
Sbjct: 2278 QAGSQQRQPGSTVHGRLETTHGQTGDTTRHGHSGYG 2313
Score = 51.2 bits (121), Expect = 2e-06
Identities = 103/461 (22%), Positives = 156/461 (33%), Gaps = 113/461 (24%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG---HGLGDALSEGVGK---AIGKEAGGAAGSKVSEA 70
GSG++ SG G+ G++ G HG G S G + G+ + G G+ S++
Sbjct: 1108 GSGQS----SGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQS 1163
Query: 71 LGQGTREAVGTGV-----RQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGA 125
G G E+ G+G + V G + G + ++ + G + G + G
Sbjct: 1164 SGCGQHES-GSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGE 1222
Query: 126 DAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG---------------- 169
S V G ET+ G I ++ GQGQ G
Sbjct: 1223 SQQVESGSTVHGRQ---ETTHGQTINTTRHSQSGQGQSTQTGSRVTRRRRSSQSENSDSE 1279
Query: 170 ---------TPWVHGYPGN---SAGSFGMNPQGAPWGQGGNG---GPPNFGTNTQGAVAQ 214
+ +H G+ +GS QG GQ G+ G G +TQ
Sbjct: 1280 VHSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQTGSRT 1339
Query: 215 PG-----YGSVRASNQNEGCTNPPPS------------------------------GSGG 239
G + S + G ++ P S G
Sbjct: 1340 SGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEAT 1399
Query: 240 GSSNSGGGSGSQSGSSGSGSNGDNNNGSS-----SGGS----------SSGSSSGGSSGG 284
G +SG G +Q GS +G G ++ SS SGGS S G SG
Sbjct: 1400 GHGHSGHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGS 1459
Query: 285 SSGGSSGNSGGSRGDSGSESSW--GSST--GSSSGNHGGSGGGNGHKPGCEKPGNEARGS 340
+ G G + G GD+ + + G ST GSS+ GSG G+
Sbjct: 1460 TVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSG 1519
Query: 341 ---GESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRNS 378
G+SG Q + + + I+ G +GD R+S
Sbjct: 1520 HTHGQSGSQHGESESIIHDRHRITH------GQTGDTTRHS 1554
Score = 45.4 bits (106), Expect = 9e-05
Identities = 98/410 (23%), Positives = 138/410 (33%), Gaps = 68/410 (16%)
Query: 17 GSGEAGPLQSGEESTGTN---IGEALGH---GLGDALSEGVGKAIGKEAGGAAGSKVSEA 70
GS P + E GT IG+ GH G G + G + G++ + S SE
Sbjct: 1603 GSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRG-SRTTGRQRSSHSESSDSE- 1660
Query: 71 LGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHG------ 124
V +GV G++ G++ + Q D RH
Sbjct: 1661 --------VHSGVSHTHTGHTHGQAGSQHGQSESIVPERHGTTHGQTGDTTRHAHYHHGL 1712
Query: 125 --ADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG 182
R + + GH+ ++ G G+ + G + G VH G G
Sbjct: 1713 TTQTGSRTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESESIVHERHGTIHG 1772
Query: 183 SFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPS------- 235
G + A G+G G+ T G + G+ S + G + P S
Sbjct: 1773 QTGDTTRHA---HSGHGQSTQTGSRTTGRRSS-GHSEYSDSEGHSGFSQRPHSRGHTHGQ 1828
Query: 236 -GSGGGSSNS-------------GGGSG-SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG 280
GS G S S G SG SQSG S +G + G G S S S
Sbjct: 1829 AGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSDSEV 1888
Query: 281 SSGGS---SGGSSGNSGGSRGDSGS-----ESSWGSSTGSSSGNHGGSGGGNGHKPGCEK 332
SGGS SG + + G+S S + TG ++ HG G + G
Sbjct: 1889 HSGGSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTT-EHGHPSHGQTIQTGSRT 1947
Query: 333 PGNEARGSGESGIQGFRG-QGVSSNMREISKEGNRLLGGSGDNYRNSETS 381
G RGSG S G GVS G +G +Y S +S
Sbjct: 1948 TGR--RGSGHSEYSDSEGPSGVSHT------HSGHTHGQAGSHYPESGSS 1989
Score = 45.1 bits (105), Expect = 1e-04
Identities = 79/323 (24%), Positives = 109/323 (33%), Gaps = 31/323 (9%)
Query: 19 GEAGPLQSGEESTGTNIGEALGHG-LGDAL-----SEGVGKAIGKEAGGAAGSKVSEALG 72
G+AG Q GE + + HG GD G G G GS SE+
Sbjct: 2052 GQAGS-QHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSD 2110
Query: 73 QGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSW 132
V + +G A + G A H T H Q D RHG S
Sbjct: 2111 SEVHSGV-SHTHSGHTYGQARSQHGESGSAIHGRQGTIHG---QTGDTTRHGQ-----SG 2161
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN---SAGSFGMNPQ 189
G G+ T + +P G H G+ +GS G Q
Sbjct: 2162 HGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGH--THSQAGSRHGQSGSSGHGRQ 2219
Query: 190 GAPWGQGGNG---GPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPS-GSGGGSSNSG 245
G GQ G+ +G +TQ G R S +E + S GS S +
Sbjct: 2220 GTTHGQTGDTTRHAHYGYGQSTQRGSRTTGR---RGSGHSESSDSEVHSWGSHTHSGHIQ 2276
Query: 246 GGSGSQSGSSGSGSNG--DNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303
G +GSQ GS +G + +G + + G S G S +G S + + S
Sbjct: 2277 GQAGSQQRQPGSTVHGRLETTHGQTGDTTRHGHSGYGQST-QTGSRSSRASHFQSHSSER 2335
Query: 304 SSWGSSTGSSSGNHGGSGGGNGH 326
GSS G++G + GH
Sbjct: 2336 QRHGSSQVWKHGSYGPAEYDYGH 2358
Score = 40.0 bits (92), Expect = 0.004
Identities = 81/336 (24%), Positives = 113/336 (33%), Gaps = 73/336 (21%)
Query: 72 GQGTREAVGTGVRQVPGFGAADALGNRVGEAA----HALGNTGHEIGRQ---AEDVIRHG 124
GQ T+ T RQ F +DA + V H+ T + G Q +E +
Sbjct: 1330 GQSTQTGSRTSGRQ--RFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESESTVHER 1387
Query: 125 ADAVRGSWQGVPGHNGAWETSGGHGIFGSQGG--LGGQGQGNP---------GGLGTPW- 172
+ G GH + GHG +G G +G G+ GG P
Sbjct: 1388 HETTYGQTGEATGHGHS-----GHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQS 1442
Query: 173 ---VHGYPGNSAGSFGMNPQGAPWGQGGNGGPP------NFGTNTQGAVAQPGYGSVRAS 223
HG G+ G G G G G + G +TQ + G R S
Sbjct: 1443 QEQTHGQAGSQHGESGSTVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGR---RGS 1499
Query: 224 NQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGS--------------GSNGDNNNGSSS 269
+E + SG GS G + QSGS G GD S S
Sbjct: 1500 GHSESSDSEVHSG---GSHTHSGHTHGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYS 1556
Query: 270 G---GSSSGSSSGG---SSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSS-------GN 316
G + +GS + G +S S S +SGGS E ++G +
Sbjct: 1557 GHEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHSREHTYGQAGSQHEEPEFTVHER 1616
Query: 317 HGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQG 352
HG + G G + G+ G G+S +G R G
Sbjct: 1617 HGTTHGQIG-----DTTGHSHSGHGQSTQRGSRTTG 1647
Score = 38.9 bits (89), Expect = 0.009
Identities = 77/307 (25%), Positives = 102/307 (33%), Gaps = 43/307 (14%)
Query: 100 GEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGG 159
GE+ + I Q D RH S Q G S GH + G G
Sbjct: 1757 GESESIVHERHGTIHGQTGDTTRHAHSGHGQSTQ--TGSRTTGRRSSGHSEYSDSEGHSG 1814
Query: 160 QGQGNPGGLGTPWVHGYPGNSAG---SFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPG 216
Q P G HG G+ G S G GQ G+ + G Q G
Sbjct: 1815 FSQ-RPHSRGH--THGQAGSQHGESESIVDERHGTTHGQTGDTS--GHSQSGHGQSTQSG 1869
Query: 217 YGSVRASNQNEGCTNPPPSGSGGGSSNSG---GGSGSQSGSSGS----------GSNGDN 263
+ ++ SGG ++SG + SQ G S S G GD
Sbjct: 1870 SSTTGRRRSGHSESSDSEVHSGGSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDT 1929
Query: 264 N-NGSSSGGSS--SGSSSGGSSGGSSG---GSSGNSGGSRGDSGSESSWGSSTGSSSGNH 317
+G S G + +GS + G G S G SG S SG T +G+H
Sbjct: 1930 TEHGHPSHGQTIQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHSG-------HTHGQAGSH 1982
Query: 318 GGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRN 377
G + H E+ G + ++ G G G S R G R G S Y +
Sbjct: 1983 YPESGSSVH----ERHGTTHGQTADTTRHGHSGHG-QSTQRGSRTTGRRASGHS--EYSD 2035
Query: 378 SETSPGM 384
SE G+
Sbjct: 2036 SEGHSGV 2042
Score = 37.4 bits (85), Expect = 0.025
Identities = 57/229 (24%), Positives = 81/229 (35%), Gaps = 23/229 (10%)
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFG-MNPQGA 191
+ PGH + S S+G G G+ G HG G G ++ G
Sbjct: 120 EDTPGHKSGYRHSSW-----SEGEEHGYSSGHSRGT-VKCRHGSNSRRLGRQGNLSSSGN 173
Query: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQ 251
G + G + G + G SV + ++ PS G SG GS S
Sbjct: 174 QEGSQKRYHRSSCGHSWSGGKDRHGSSSVEL-RERINKSHISPSRESGEEYESGSGSNSW 232
Query: 252 SGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSES-SWGSST 310
+ G S G +SG S + G+S GDSG S + G S
Sbjct: 233 ERKG--------HGGLSCGLETSGHESNSTQSRIREQKLGSSCSGSGDSGRRSHACGYSN 284
Query: 311 GSSSGN-HGGSGGGNGHKPGCEKPGNE---ARGSGESGIQGFRGQGVSS 355
S G S H+ G + GN+ + +SGI+G +G G S
Sbjct: 285 SSGCGRPQNASSSCQSHRFGGQ--GNQFSYIQSGCQSGIKGGQGHGCVS 331
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 93.2 bits (230), Expect = 4e-19
Identities = 53/132 (40%), Positives = 62/132 (46%), Gaps = 2/132 (1%)
Query: 227 EGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSS 286
EG + G GGGS G G GS G S G +G + GSS GG GSS GGSSGG
Sbjct: 454 EGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGY 513
Query: 287 GGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ 346
GG G+S G G S S G S+G G +GG G G G G + G +S
Sbjct: 514 GG--GSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSS 571
Query: 347 GFRGQGVSSNMR 358
G G+ S R
Sbjct: 572 GSVGESSSKGPR 583
Score = 91.3 bits (225), Expect = 1e-18
Identities = 56/131 (42%), Positives = 63/131 (48%), Gaps = 12/131 (9%)
Query: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG 253
G+G +GG G + G GYG + + G G GGG S GG G G
Sbjct: 455 GEGSSGGGGRGGGSFGG-----GYGGGSSGGGSSG------GGHGGGHGGSSGG-GYGGG 502
Query: 254 SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSS 313
SSG GS+G G SS G GSSSGG GGSSGG G GG GS S G GSS
Sbjct: 503 SSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSS 562
Query: 314 SGNHGGSGGGN 324
SG H S G+
Sbjct: 563 SGGHKSSSSGS 573
Score = 84.7 bits (208), Expect = 1e-16
Identities = 57/131 (43%), Positives = 65/131 (49%), Gaps = 6/131 (4%)
Query: 240 GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGD 299
G +SGGG G GS G G G ++ G SSGG G G S GG GGSSG G S G
Sbjct: 455 GEGSSGGG-GRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSG-GGSSGGG 512
Query: 300 SGSESSWGSSTGSSSGNHGG--SGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSS-- 355
G SS G GSSSG +GG SGGG G G G + G G G G SS
Sbjct: 513 YGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSG 572
Query: 356 NMREISKEGNR 366
++ E S +G R
Sbjct: 573 SVGESSSKGPR 583
Score = 77.8 bits (190), Expect = 2e-14
Identities = 60/163 (36%), Positives = 68/163 (41%), Gaps = 41/163 (25%)
Query: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGA 211
GS GG GG+G G+ GG GY G S+G G + G G GG+ G
Sbjct: 457 GSSGG-GGRGGGSFGG-------GYGGGSSGG-GSSGGGHGGGHGGSSGG---------- 497
Query: 212 VAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGG 271
GYG SGGGSS G G GS SG G S+G GSS GG
Sbjct: 498 ----GYGG---------------GSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGG 538
Query: 272 SSS---GSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311
GSS GGSS G G +SGG + S SS G
Sbjct: 539 GGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSKG 581
Score = 77.8 bits (190), Expect = 2e-14
Identities = 60/162 (37%), Positives = 72/162 (44%), Gaps = 41/162 (25%)
Query: 144 TSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPN 203
+SGG G G G GG G G+ GG G+S G G GG+GG
Sbjct: 458 SSGGGGRGGGSFG-GGYGGGSSGG----------GSSGGGHG----------GGHGGS-- 494
Query: 204 FGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDN 263
+ GYG + + G G GG S+SGG GS SG G GS+G
Sbjct: 495 ---------SGGGYGGGSSGGGSSG-------GGYGGGSSSGGHGGSSSGGYGGGSSGGG 538
Query: 264 NNGSSSGGSSSGSSSGGSSGG--SSGGSSGNSGGSRGDSGSE 303
G G S GSSSGG GG SSGG +S GS G+S S+
Sbjct: 539 GGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSK 580
Score = 75.5 bits (184), Expect = 8e-14
Identities = 65/158 (41%), Positives = 70/158 (44%), Gaps = 14/158 (8%)
Query: 235 SGSGGGSSNSGGGSG-------SQSGSSGSG-SNGDNNNGSSSGGSSSGSSSGGSSGGSS 286
SG GGG GGG G S GS G G S+G + GS S GSS G GGSSGG
Sbjct: 16 SGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGG-Y 74
Query: 287 GGSSGNSGGS-RGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGI 345
GG G GGS RG GS S GS GS G G G G G G G G G
Sbjct: 75 GGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFGG- 133
Query: 346 QGFRGQG--VSSNMREISKEGNRLLGGSGDNYRNSETS 381
GF G G +S N + + N L D R E S
Sbjct: 134 -GFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEES 170
Score = 71.6 bits (174), Expect = 1e-12
Identities = 52/135 (38%), Positives = 54/135 (40%), Gaps = 14/135 (10%)
Query: 253 GSSGSGSNGDNNNGSSSGGSSSGSSSGGSS-----GGSSGGSSGNSGGSRGDSGSESSWG 307
GSSG G G G S GG G SSGG S GG GGSSG G G S G
Sbjct: 457 GSSGGGGRG----GGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGG 512
Query: 308 SSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRL 367
GSSSG HGGS G G+ G G G G SG G G S G
Sbjct: 513 YGGGSSSGGHGGSSSG-GYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGG----SSSGGHK 567
Query: 368 LGGSGDNYRNSETSP 382
SG +S P
Sbjct: 568 SSSSGSVGESSSKGP 582
Score = 59.3 bits (142), Expect = 6e-09
Identities = 45/132 (34%), Positives = 50/132 (37%), Gaps = 9/132 (6%)
Query: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG 253
G GG GG G GS+ + G + S G GG SG G
Sbjct: 17 GGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGG 76
Query: 254 SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSS 313
G G G S GS SS GGS GGS GG G+ GG GS G G
Sbjct: 77 LGGFG-------GGSFRGSYGSSSFGGSYGGSFGG--GSFGGGSFGGGSFGGGGFGGGGF 127
Query: 314 SGNHGGSGGGNG 325
G GG GG+G
Sbjct: 128 GGGFGGGFGGDG 139
Score = 48.9 bits (115), Expect = 8e-06
Identities = 39/102 (38%), Positives = 43/102 (42%), Gaps = 10/102 (9%)
Query: 284 GSSGGSSGNSGGSRGD--SGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSG 341
GSSGG G GGS G G S GSS G G HGGS GG G+ G G+ G G
Sbjct: 457 GSSGGG-GRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGG-GYGGGSSGGGSSGGGYG 514
Query: 342 ESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRNSETSPG 383
G G G SS+ G GG G Y + G
Sbjct: 515 GGSSSG--GHGGSSS----GGYGGGSSGGGGGGYGGGSSGGG 550
Score = 45.8 bits (107), Expect = 7e-05
Identities = 43/145 (29%), Positives = 55/145 (37%), Gaps = 20/145 (13%)
Query: 153 SQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNP-QGAPWGQGGNGGPPNFGTNT-QG 210
S GG GG G G GG+ + + G+ G F G + +G +GG G++ G
Sbjct: 16 SGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYG 75
Query: 211 AVAQPGYGSVRASNQNEGCTNPPPSGSGGGS---SNSGGGSGSQSGSSGSGSNGDNNNGS 267
+ G GS R S + GGGS + GGGS G
Sbjct: 76 GLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGS---------------FGGG 120
Query: 268 SSGGSSSGSSSGGSSGGSSGGSSGN 292
GG G GG GG G SGN
Sbjct: 121 GFGGGGFGGGFGGGFGGDGGLLSGN 145
Score = 42.4 bits (98), Expect = 8e-04
Identities = 36/124 (29%), Positives = 45/124 (36%), Gaps = 46/124 (37%)
Query: 137 GHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQG 196
G +G + GG+G S GG GG G GY G S+G G G
Sbjct: 502 GSSGGGSSGGGYGGGSSSGGHGGSSSG-----------GYGGGSSGG----------GGG 540
Query: 197 GNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSG 256
G GG + G ++ G G GG S+SGG S SGS G
Sbjct: 541 GYGGGSSGGGSSSG-------------------------GGYGGGSSSGGHKSSSSGSVG 575
Query: 257 SGSN 260
S+
Sbjct: 576 ESSS 579
Score = 39.3 bits (90), Expect = 0.007
Identities = 44/156 (28%), Positives = 60/156 (38%), Gaps = 24/156 (15%)
Query: 46 ALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHA 105
+L EG G + G GG G G G+ +G G G + G G +
Sbjct: 451 SLLEGEGSSGG---GGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSS--GGGYGGGSSG 505
Query: 106 LGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNP 165
G++G G GS G GH G+ +SGG+G GS GG GG G
Sbjct: 506 GGSSGGGYGG--------------GSSSG--GHGGS--SSGGYG-GGSSGGGGGGYGGGS 546
Query: 166 GGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGP 201
G G+ GY G S+ + G+ + GP
Sbjct: 547 SGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSKGP 582
Score = 36.6 bits (83), Expect = 0.043
Identities = 34/107 (31%), Positives = 41/107 (38%), Gaps = 22/107 (20%)
Query: 145 SGGHGIFGSQGG-LGGQGQGNPGGLGTPWVHGYPGNS-AGSFGMNPQGAPWGQGGNGGPP 202
SGG GS GG G G GGLG G+ G S GS+G + G +G GG
Sbjct: 53 SGGSFSRGSSGGGCFGGSSGGYGGLG-----GFGGGSFRGSYGSSSFGGSYGGSFGGGSF 107
Query: 203 NFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
G+ G+ G+G G GGG GG G
Sbjct: 108 GGGSFGGGSFGGGGFGG---------------GGFGGGFGGGFGGDG 139
Score = 32.7 bits (73), Expect = 0.62
Identities = 44/176 (25%), Positives = 56/176 (31%), Gaps = 58/176 (32%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTR 76
G G G G S G + G GHG G S G G G GG++G
Sbjct: 465 GGGSFGGGYGGGSSGGGSSGG--GHGGGHGGSSGGGYGGGSSGGGSSGG----------- 511
Query: 77 EAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVP 136
G+G + G HG + G G
Sbjct: 512 -----------GYGGGSSSGG-------------------------HGGSSSGGYGGGSS 535
Query: 137 GHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAP 192
G G GG+G GS GG G G GG + G+ +S+GS G + P
Sbjct: 536 GGGG-----GGYG-GGSSGGGSSSGGGYGGGSSS---GGHKSSSSGSVGESSSKGP 582
Score = 31.2 bits (69), Expect = 1.8
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 9/84 (10%)
Query: 144 TSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS--AGSFGMNPQGAPWGQGGNGGP 201
+SGG+G G GG +G G + + G S GSFG G +G GG GG
Sbjct: 70 SSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFG----GGSFGGGGFGG- 124
Query: 202 PNFGTNTQGAVAQPGYGSVRASNQ 225
FG G G G + + N+
Sbjct: 125 GGFGGGFGGGFG--GDGGLLSGNE 146
Score = 28.9 bits (63), Expect = 9.0
Identities = 27/77 (35%), Positives = 32/77 (41%), Gaps = 17/77 (22%)
Query: 124 GADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGS 183
G + RGS+ G G++ S G G FG GG G G GG G G
Sbjct: 81 GGGSFRGSY-GSSSFGGSYGGSFGGGSFG--GGSFGGGSFGGGGFG-----------GGG 126
Query: 184 FGMNPQGAPWGQGGNGG 200
FG G G GG+GG
Sbjct: 127 FG---GGFGGGFGGDGG 140
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 92.8 bits (229), Expect = 5e-19
Identities = 76/244 (31%), Positives = 100/244 (40%), Gaps = 38/244 (15%)
Query: 144 TSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPN 203
++GG+G S GQ PG P P +++GS+G + Q + +GQ P
Sbjct: 77 STGGYGSSQSSQSSYGQQSSYPGYGQQP----APSSTSGSYGSSSQSSSYGQ------PQ 126
Query: 204 FGTNTQGAVAQPGYGSVRASNQNEGCTNPPP---------SGSGGGSSNSGGGSGSQ--- 251
G+ +Q QP YG + S + NPP S SGGG GGG+ Q
Sbjct: 127 SGSYSQ----QPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQS 182
Query: 252 SGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311
S SSG GS G N SGG SG GG G SG GG G + SS G
Sbjct: 183 SMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPR 242
Query: 312 SSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRL-LGG 370
G GG GG G G G + G R QG + + + + N + + G
Sbjct: 243 GRGGGRGGRGGMGGSDRG-----------GFNKFGGPRDQGSRHDSEQDNSDNNTIFVQG 291
Query: 371 SGDN 374
G+N
Sbjct: 292 LGEN 295
Score = 66.2 bits (160), Expect = 5e-11
Identities = 52/154 (33%), Positives = 60/154 (38%), Gaps = 17/154 (11%)
Query: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGA 211
G G GG+G+G P G G GY G +G G G P G GG GG G
Sbjct: 378 GGGNGRGGRGRGGPMGRG-----GYGGGGSGGGGRG--GFPSGGGGGGGQQRAG---DWK 427
Query: 212 VAQPGYGSVRASNQNE--GCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSS 269
P ++ S +NE C P P G GGG G G G G G + G
Sbjct: 428 CPNPTCENMNFSWRNECNQCKAPKPDGPGGGPG--GSHMGGNYGDDRRGGRGGYDRGGYR 485
Query: 270 GGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303
G G GG GG GG G G + DS E
Sbjct: 486 G---RGGDRGGFRGGRGGGDRGGFGPGKMDSRGE 516
Score = 54.7 bits (130), Expect = 2e-07
Identities = 60/196 (30%), Positives = 72/196 (36%), Gaps = 20/196 (10%)
Query: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG-----GGSSNSGG 246
P+GQ G T+T G Q Y S S T P G G G S +S
Sbjct: 32 PYGQQSYSGYSQ-STDTSG-YGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQS 89
Query: 247 GSGSQSGSSGSGSNGDNNNGSSSGG--SSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSES 304
G QS G G + S+SG SSS SSS G S + GG + G +
Sbjct: 90 SYGQQSSYPGYGQQPAPS--STSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQ 147
Query: 305 SWGSSTG--------SSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSN 356
S+ G SSSG GG GGG + + G G Q G G S
Sbjct: 148 SYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGG 207
Query: 357 MREISKEGNRLLGGSG 372
+ G R GGSG
Sbjct: 208 YGQ-QDRGGRGRGGSG 222
Score = 54.3 bits (129), Expect = 2e-07
Identities = 60/197 (30%), Positives = 79/197 (40%), Gaps = 24/197 (12%)
Query: 206 TNTQGAV-AQPGYGSVRASNQNEG-------CTNPPPSGSGGGSSNSGG-----GSGSQS 252
T + GA QPG G + S+Q G + SG G S +S G G G+QS
Sbjct: 11 TQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQS 70
Query: 253 GSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWG---SS 309
G GS G + SS S SS G SS + GS G S SS+G S
Sbjct: 71 TPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSS--TSGSYGSSSQSSSYGQPQSG 128
Query: 310 TGSSSGNHGGSGGGNGHKPGCEKP---GNEARGSGESGIQGFRGQGVSSNMREISKEGNR 366
+ S ++GG G + P G + + + SG G G G + + S
Sbjct: 129 SYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSG- 187
Query: 367 LLGGSGDNYRNSETSPG 383
GGSG Y N + S G
Sbjct: 188 --GGSGGGYGNQDQSGG 202
Score = 50.4 bits (119), Expect = 3e-06
Identities = 83/365 (22%), Positives = 114/365 (31%), Gaps = 69/365 (18%)
Query: 40 GHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRV 99
G+G + + G G GG G S ++ G G G + G G + G +
Sbjct: 154 GYGQQNQYNSSSGGGGGGGGGGNYGQDQS-SMSSGGGSGGGYGNQDQSGGGGSGGYGQQ- 211
Query: 100 GEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGG 159
G +G G G G +G +E G G G +GG+GG
Sbjct: 212 DRGGRGRGGSGGGGG---------------GGGGGYNRSSGGYEPRGRGGGRGGRGGMGG 256
Query: 160 QGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFG----------TNTQ 209
+G G P G +S N G G N + TN +
Sbjct: 257 SDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKK 316
Query: 210 GAVAQPGYGSVRASNQNEG----CTNPPPSGSGG-----GSSNSGG-------------G 247
+ R + + +G + PPS G SG
Sbjct: 317 TGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFN 376
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG-SSGGSSGGSSGNSGGSRGDS----GS 302
G +G G G G G GG S G GG SGG GG +G + +
Sbjct: 377 RGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENM 436
Query: 303 ESSWGSS---------TGSSSGNHGGSGGGN------GHKPGCEKPGNEARGSGESGIQG 347
SW + G G G GGN G + G ++ G RG G +G
Sbjct: 437 NFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRG 496
Query: 348 FRGQG 352
RG G
Sbjct: 497 GRGGG 501
Score = 45.8 bits (107), Expect = 7e-05
Identities = 38/140 (27%), Positives = 48/140 (34%), Gaps = 14/140 (10%)
Query: 196 GGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSS 255
GGNG G G + + GYG + G GG S GGG G Q
Sbjct: 379 GGNG---RGGRGRGGPMGRGGYGGGGSGG----------GGRGGFPSGGGGGGGQQRAGD 425
Query: 256 GSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNS-GGSRGDSGSESSWGSSTGSSS 314
N N + S + G GG G+ GG+ GD G G
Sbjct: 426 WKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYR 485
Query: 315 GNHGGSGGGNGHKPGCEKPG 334
G G GG G + G ++ G
Sbjct: 486 GRGGDRGGFRGGRGGGDRGG 505
Score = 43.1 bits (100), Expect = 5e-04
Identities = 95/433 (21%), Positives = 131/433 (30%), Gaps = 89/433 (20%)
Query: 18 SGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQ---- 73
+G G QS + S G G+G A S G + G S + Q
Sbjct: 78 TGGYGSSQSSQSSYGQQSSYP-GYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSY 136
Query: 74 -GTREAVGTGVRQVP--GFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRG 130
G +++ G P G+G + + G G G G+ + G
Sbjct: 137 GGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGG--GGGGGNYGQDQSSMSSGG------ 188
Query: 131 SWQGVPGHNGAWETSGGHGIFG-SQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQ 189
G G G + SGG G G Q GG+G+G GG G GY +S G
Sbjct: 189 ---GSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRG 245
Query: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGG-- 247
G G+GG GG G N G G R ++ + N G G + +
Sbjct: 246 GGRGGRGGMGGSDRGGFNKFGGPRDQG---SRHDSEQDNSDNNTIFVQGLGENVTIESVA 302
Query: 248 ----------SGSQSGSSGSGSNGDNNNGSSSGGSS----------------SGSSSGGS 281
+ ++G D G G ++ G G+
Sbjct: 303 DYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGN 362
Query: 282 ----------SGGSSGGSSGNSGGSRG---DSGSESSWGSSTGSSSGNHGGSGGGNGHK- 327
+ + GG +G G RG G GS G G G GGG G +
Sbjct: 363 PIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQR 422
Query: 328 --------PGCE----------------KPGNEARGSGESGIQGFRGQGVSSNMREISKE 363
P CE KP G G S + G G +
Sbjct: 423 AGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRG 482
Query: 364 GNRLLGGSGDNYR 376
G R GG +R
Sbjct: 483 GYRGRGGDRGGFR 495
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 88.2 bits (217), Expect = 1e-17
Identities = 55/126 (43%), Positives = 62/126 (49%), Gaps = 6/126 (4%)
Query: 239 GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGS-SSGGSSGGSSGGS--SGNSGG 295
GG S GGG G SG S GS G + GG GS SGGSS GS GGS SG GG
Sbjct: 514 GGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGG 573
Query: 296 SRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSS 355
G GS SS G G S G GGS GG G G RGS G+ + G SS
Sbjct: 574 GHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGV---KSSGGSS 630
Query: 356 NMREIS 361
+++ +S
Sbjct: 631 SVKFVS 636
Score = 81.6 bits (200), Expect = 1e-15
Identities = 59/155 (38%), Positives = 69/155 (44%), Gaps = 9/155 (5%)
Query: 239 GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
G S G S S S+ + G S GG G SGGSS GS GGS G+ GG G
Sbjct: 488 GEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGG 547
Query: 299 DSGSESSWGSSTGSSSGNHGGSGGGNGH-------KPGCEKPGNEARGSGESGIQGFRG- 350
GS S GSS GS G++G GGG GH G + G+ G G SG +G G
Sbjct: 548 GRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGG 607
Query: 351 -QGVSSNMREISKEGNRLLGGSGDNYRNSETSPGM 384
G S R S G + GGS S T G+
Sbjct: 608 SSGGSIGGRGSSSGGVKSSGGSSSVKFVSTTYSGV 642
Score = 80.9 bits (198), Expect = 2e-15
Identities = 49/112 (43%), Positives = 54/112 (48%), Gaps = 2/112 (1%)
Query: 216 GYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSG 275
GYGS +S + G + SG GGG GSG S SG GS G G G SG
Sbjct: 524 GYGSGGSSYGSGGGSYG--SGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSG 581
Query: 276 SSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK 327
SSSGG GGS GG G+SGG GS GSSSG SGG + K
Sbjct: 582 SSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSVK 633
Score = 79.7 bits (195), Expect = 4e-15
Identities = 55/136 (40%), Positives = 66/136 (48%), Gaps = 20/136 (14%)
Query: 175 GYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPP 234
G G G +G G+ +G GG ++G+ G + YGS +S
Sbjct: 516 GSRGGGGGGYGSG--GSSYGSGGG----SYGSGGGGGGGRGSYGSGGSSY---------- 559
Query: 235 SGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG 294
GSGGGS SGGG G GS GSGS+ G S GG S GS GGSSGGS G G
Sbjct: 560 -GSGGGSYGSGGGGGGH-GSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRG 617
Query: 295 GSRGDSGSESSWGSST 310
S G G +SS GSS+
Sbjct: 618 SSSG--GVKSSGGSSS 631
Score = 76.6 bits (187), Expect = 4e-14
Identities = 52/130 (40%), Positives = 62/130 (47%), Gaps = 7/130 (5%)
Query: 232 PPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG-----SSGGSS 286
P S S S + G GS+ G G +G ++ GS G SG GG SGGSS
Sbjct: 499 PNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSS 558
Query: 287 GGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ 346
GS G S GS G G S+GS + SS G GGSGGG G G G + G G G +
Sbjct: 559 YGSGGGSYGSGGGGGGHGSYGSGS-SSGGYRGGSGGGGGGSSGGRGSGGGSSG-GSIGGR 616
Query: 347 GFRGQGVSSN 356
G GV S+
Sbjct: 617 GSSSGGVKSS 626
Score = 69.3 bits (168), Expect = 6e-12
Identities = 58/147 (39%), Positives = 67/147 (45%), Gaps = 33/147 (22%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPW 193
G G G SGG +GS GG G G G GG G+ +G G+S GS G +
Sbjct: 516 GSRGGGGGGYGSGGSS-YGSGGGSYGSGGGGGGGRGS---YGSGGSSYGS-----GGGSY 566
Query: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG 253
G GG GG G+GS + + + G GSGGG S GG GS G
Sbjct: 567 GSGGGGG---------------GHGSYGSGSSSGGYRG----GSGGGGGGSSGGRGSGGG 607
Query: 254 SSGSGSNGDNNNGSSSGG--SSSGSSS 278
SSG G GSSSGG SS GSSS
Sbjct: 608 SSGGSIGG---RGSSSGGVKSSGGSSS 631
Score = 62.0 bits (149), Expect = 1e-09
Identities = 48/150 (32%), Positives = 59/150 (39%), Gaps = 9/150 (6%)
Query: 236 GSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGG 295
G GGGS +GGG GS+S + GS + + + GG SG G GG GG G G
Sbjct: 50 GGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGF 109
Query: 296 SRGDSGSESSWGSSTGS---SSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRG-- 350
G G G +G G GG G G G+ P C G + +S +Q
Sbjct: 110 GGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEI 169
Query: 351 ----QGVSSNMREISKEGNRLLGGSGDNYR 376
Q V S RE K N D R
Sbjct: 170 DPEIQKVKSREREQIKSLNNQFASFIDKVR 199
Score = 59.7 bits (143), Expect = 5e-09
Identities = 41/133 (30%), Positives = 48/133 (36%), Gaps = 8/133 (6%)
Query: 205 GTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNN 264
G + G + G + + + G GG S+ GGG GS G GS N
Sbjct: 10 GYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVN 69
Query: 265 NGSSSG-------GSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNH 317
G S G GS GG GG G G GG G G GS G
Sbjct: 70 LGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGF 129
Query: 318 GGSG-GGNGHKPG 329
GG G GG G+ G
Sbjct: 130 GGGGFGGGGYGGG 142
Score = 48.5 bits (114), Expect = 1e-05
Identities = 44/124 (35%), Positives = 49/124 (39%), Gaps = 15/124 (12%)
Query: 241 SSNSG--GGSGSQSGSSGSGSNGDNNNGSS---SGGSSSGSSSGGSSGGSSGGSSG---- 291
SS SG G G SGS+G + SS SGG SS G GGS G G
Sbjct: 6 SSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSR 65
Query: 292 ---NSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGF 348
N GGS+ S S + G G +GG G G G G G G G G GF
Sbjct: 66 SLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGG---GFGGGGFGGGGIGGGGFGGF 122
Query: 349 RGQG 352
G
Sbjct: 123 GSGG 126
Score = 42.7 bits (99), Expect = 6e-04
Identities = 37/113 (32%), Positives = 44/113 (38%), Gaps = 21/113 (18%)
Query: 146 GGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGS-FGMNPQGAPWGQGGNGGPPNF 204
GG G FG+ GG G + N GG + + G GS FG G +G GG GG
Sbjct: 51 GGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGG---- 106
Query: 205 GTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG-GSGSQSGSSG 256
G G + G+G GSGGG GG G G G G
Sbjct: 107 GGFGGGGIGGGGFGGF---------------GSGGGGFGGGGFGGGGYGGGYG 144
Score = 41.6 bits (96), Expect = 0.001
Identities = 30/95 (31%), Positives = 33/95 (34%), Gaps = 1/95 (1%)
Query: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGG-SGSQS 252
G GG G ++ V G S+ S G G GG GGG G
Sbjct: 50 GGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGF 109
Query: 253 GSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSG 287
G G G G GS GG G GG GG G
Sbjct: 110 GGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYG 144
Score = 39.3 bits (90), Expect = 0.007
Identities = 37/137 (27%), Positives = 53/137 (38%), Gaps = 7/137 (5%)
Query: 65 SKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHG 124
S++S +V T + G G+ G G + G+ G G G
Sbjct: 491 SRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRG 550
Query: 125 ADAVRGSWQGVPGHN-GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGS 183
+ GS G G + G+ GGHG +GS GG +G GG G G GS
Sbjct: 551 SYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGY-RGGSGGGG-----GGSSGGRGS 604
Query: 184 FGMNPQGAPWGQGGNGG 200
G + G+ G+G + G
Sbjct: 605 GGGSSGGSIGGRGSSSG 621
Score = 37.0 bits (84), Expect = 0.033
Identities = 39/128 (30%), Positives = 44/128 (34%), Gaps = 19/128 (14%)
Query: 263 NNNGSSSGGSSSGSSSG---------GSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSS 313
+ +G SGG S S+G SS SGG G G GS + G S
Sbjct: 7 SRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRS 66
Query: 314 SGNHGGS---------GGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEG 364
N GGS GGG G G G G G G GF G G+ G
Sbjct: 67 LVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGG-GGFGGGGIGGGGFGGFGSG 125
Query: 365 NRLLGGSG 372
GG G
Sbjct: 126 GGGFGGGG 133
Score = 35.4 bits (80), Expect = 0.096
Identities = 40/150 (26%), Positives = 55/150 (36%), Gaps = 22/150 (14%)
Query: 18 SGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTRE 77
SGE P S ST G G G G G G GS S G G R
Sbjct: 494 SGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSG---GSSYGSGGGSYGSGGGGGGGRG 550
Query: 78 AVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPG 137
+ G+G G+ G + G+ G G + +G+ + G ++G G
Sbjct: 551 SYGSG-------------GSSYGSGGGSYGSGGGGGGHGS-----YGSGSSSGGYRGGSG 592
Query: 138 HNGAWETSG-GHGIFGSQGGLGGQGQGNPG 166
G + G G G S G +GG+G + G
Sbjct: 593 GGGGGSSGGRGSGGGSSGGSIGGRGSSSGG 622
Score = 30.8 bits (68), Expect = 2.4
Identities = 36/134 (26%), Positives = 46/134 (34%), Gaps = 7/134 (5%)
Query: 40 GHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNR- 98
G+ G S G I + + S G G + G G FGA G+R
Sbjct: 10 GYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGS---FGAGGGFGSRS 66
Query: 99 ---VGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQG 155
+G + + GR + +G G G G G GG G FGS G
Sbjct: 67 LVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGG 126
Query: 156 GLGGQGQGNPGGLG 169
G G G GG G
Sbjct: 127 GGFGGGGFGGGGYG 140
Score = 30.8 bits (68), Expect = 2.4
Identities = 40/147 (27%), Positives = 52/147 (35%), Gaps = 22/147 (14%)
Query: 56 GKEAGGAAG--SKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEI 113
G + G+AG + TR + G G R G + G G + +L N G
Sbjct: 15 GGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSK 74
Query: 114 GRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWV 173
G + G G G G GG G GG+GG G G
Sbjct: 75 SISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFG----GGGIGGGGFG---------- 120
Query: 174 HGYPGNSAGSFGMNPQGAPWGQGGNGG 200
G+ G+ G FG G +G GG GG
Sbjct: 121 -GF-GSGGGGFG----GGGFGGGGYGG 141
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 86.7 bits (213), Expect = 4e-17
Identities = 88/308 (28%), Positives = 106/308 (34%), Gaps = 46/308 (14%)
Query: 82 GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGA 141
G++ +PG G + GE G+ G A DA +G PG GA
Sbjct: 639 GLQGLPGTGGPPGENGKPGEPGPK-GDAG------APGAPGGKGDAGAPGERGPPGLAGA 691
Query: 142 WETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAGSFGMNPQG---APWGQGG 197
GG G G +GG G G G PG GTP + G PG G P+G P G G
Sbjct: 692 PGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGA 751
Query: 198 NGGPPNFGTNTQ-------------------GAVAQPGYGSVRASNQNEGCTNPP-PSGS 237
+G P G GA PG R S G T PP P+G
Sbjct: 752 DGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGF 811
Query: 238 GGGSSNSG--GGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSG--------GSSGGSSG 287
G +G GG G + G G GGS G GS GG
Sbjct: 812 PGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGA 871
Query: 288 GSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGH-----KPGCEKPGNEARGSGE 342
+ G G GS + G S S G G G+ PG P +A GE
Sbjct: 872 AGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGE 931
Query: 343 SGIQGFRG 350
G G +G
Sbjct: 932 KGSPGAQG 939
Score = 78.2 bits (191), Expect = 1e-14
Identities = 95/350 (27%), Positives = 117/350 (33%), Gaps = 26/350 (7%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTR 76
G+ A L+ G G N + G+ G+ G + E G
Sbjct: 420 GANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLP 479
Query: 77 EAVGTGVRQVPGFGAADALGNRVGEAAHA--LGNTGHEIGRQAEDVIRHGADAVRGS--W 132
A G R PGF GE A G G R A G D V G
Sbjct: 480 GAAGE--RGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAG--EPGRDGVPGGPGM 535
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGG-LGTPWVHGYPGNSAGSFGMNPQGA 191
+G+PG G + G G GSQG G G P G G P V G+PG G
Sbjct: 536 RGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGE 595
Query: 192 PWGQGGNG--GPP--NFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGG 247
G GG G GPP N T QG G G ++G T PP G +GG
Sbjct: 596 RGGPGGPGPQGPPGKNGETGPQGPPGPTGPGG------DKGDTGPPGPQGLQGLPGTGGP 649
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGS--RGDSGSESS 305
G G GD + GG + G G+ G GG+ G G + +
Sbjct: 650 PGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGA 709
Query: 306 WGSSTGSSSGNHGGSGGGNGHKPGCEKPG-----NEARGSGESGIQGFRG 350
G + G G G + G PG E G G G+ G G
Sbjct: 710 AGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDG 759
Score = 76.6 bits (187), Expect = 4e-14
Identities = 110/394 (27%), Positives = 139/394 (35%), Gaps = 83/394 (21%)
Query: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
G G + G +A G R PG A L G G E G+ A
Sbjct: 660 GPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPP-------GPEGGKGAAGP 712
Query: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQG-------QGNPGGLGTPWV 173
A QG+PG G + G G G GG G G +G G +G P
Sbjct: 713 PGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGP 772
Query: 174 HGYPGNSA--GSFGM----NPQGAPWGQGGNGGPPNFG--TNTQGAVAQPGYGSVRASNQ 225
G PG+ G+ G+ P+G+P G+ G GPP G +PG R +
Sbjct: 773 AGQPGDKGEGGAPGLPGIAGPRGSP-GERGETGPPGPAGFPGAPGQNGEPGGKGERGAPG 831
Query: 226 NEGCTNPP-----PSGSG----------GGSSNSGGGSGSQS--GSSG-SGSNGDNNNGS 267
+G PP P GSG G S GG G+ G+ G G G N N
Sbjct: 832 EKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPG 891
Query: 268 SSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWGS-------------STGS 312
G S S G + G+ G+ G G +GD+G GS
Sbjct: 892 PPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAG 951
Query: 313 SSGNHG-----------GSGGGNGHKPGCEKPGNEARG-SGESGIQGFRG-QGVSSNMRE 359
+G G GS G G K KPG A G SGE G G +G G++ E
Sbjct: 952 ITGARGLAGPPGMPGPRGSPGPQGVKGESGKPG--ANGLSGERGPPGPQGLPGLAGTAGE 1009
Query: 360 ISKEGN----------RLLGGSGDNYRNSETSPG 383
++GN GG GD R SPG
Sbjct: 1010 PGRDGNPGSDGLPGRDGSPGGKGD--RGENGSPG 1041
Score = 75.9 bits (185), Expect = 6e-14
Identities = 85/315 (26%), Positives = 109/315 (34%), Gaps = 39/315 (12%)
Query: 82 GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVI--RHGADAVRGSWQGVPGHN 139
G+ PG R GE G TG G + E+ + +GA G +G PG
Sbjct: 255 GIPGFPGMKGHRGFDGRNGEK----GETGAP-GLKGENGLPGENGAPGPMGP-RGAPGER 308
Query: 140 GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNG 199
G G G G+ G G GQ PG G P G+PG+ + P G+P G NG
Sbjct: 309 GRPGLPGAAGARGNDGARGSDGQ--PGPPGPPGTAGFPGSPGAKGEVGPAGSP---GSNG 363
Query: 200 GPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGS-G 258
P G +PG Q PP G S G G +G G+ G
Sbjct: 364 AP--------GQRGEPG-------PQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPG 408
Query: 259 SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWGSSTGSSSGN 316
G +G + + GG+ G+ G G G RG++G G+
Sbjct: 409 LMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDG 468
Query: 317 HGGSGGGNG--------HKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLL 368
G G NG PG P GE G G RG + R + E R
Sbjct: 469 SPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDG 528
Query: 369 GGSGDNYRNSETSPG 383
G R SPG
Sbjct: 529 VPGGPGMRGMPGSPG 543
Score = 73.6 bits (179), Expect = 3e-13
Identities = 81/275 (29%), Positives = 102/275 (37%), Gaps = 32/275 (11%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAGSFGM-NPQGA 191
G PG G G G G +G G QG G PG LG + G G AG GM P+G+
Sbjct: 912 GAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARG-LAGPPGMPGPRGS 970
Query: 192 PWGQG--GNGGPP--NFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGG 247
P QG G G P N + +G G + + G P S G S GG
Sbjct: 971 PGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGG 1030
Query: 248 SGSQSGSSGSGSNGDNNNGSSSG--GSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESS 305
G + + G+ G + G G + S G SG + + GSRG G +
Sbjct: 1031 KGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGP 1090
Query: 306 WGSSTGSSSGNHGGSG-------GGNGHKPGCEKPGNEARGSGESGIQGFRG-------- 350
G +G G +G GN PG P + G G G RG
Sbjct: 1091 RGDK--GETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPP 1148
Query: 351 --QGVSSNMREISKEGNRLLGGSGDNYRNSETSPG 383
G S + I G R G G+ R SE SPG
Sbjct: 1149 GKDGTSGHPGPIGPPGPR--GNRGE--RGSEGSPG 1179
Score = 72.8 bits (177), Expect = 5e-13
Identities = 82/282 (29%), Positives = 108/282 (38%), Gaps = 30/282 (10%)
Query: 105 ALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQ-G 163
A+G +G G+ E R G RG G PG G G G+ G +G G G+ G
Sbjct: 220 AIGPSG-PAGKDGESG-RPGRPGERGL-PGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKG 276
Query: 164 NPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRAS 223
G G +G PG + M P+GAP G+ G G P GA G R S
Sbjct: 277 ETGAPGLKGENGLPGENGAPGPMGPRGAP-GERGRPGLP-------GAAGARGNDGARGS 328
Query: 224 NQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGS-GSNGDNNNGSSSGGSSSGSSSGGSS 282
+ G PP + GS + G + G +GS GSNG G + G
Sbjct: 329 DGQPGPPGPPGTAGFPGSPGAKG----EVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPG 384
Query: 283 GGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGE 342
GS G G G +G + G G+ G G + G +PG GE
Sbjct: 385 PPGINGSPGGK-GEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNG-AKGE 442
Query: 343 SGIQGFRGQ----GVSSNMREISKEG-------NRLLGGSGD 373
G +G RG+ GV E K+G N L G +G+
Sbjct: 443 PGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGE 484
Score = 72.4 bits (176), Expect = 7e-13
Identities = 82/301 (27%), Positives = 100/301 (33%), Gaps = 47/301 (15%)
Query: 124 GADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGS 183
G D RGS G PG G T+G G G++G +G G +PG G P G PG +
Sbjct: 321 GNDGARGS-DGQPGPPGPPGTAGFPGSPGAKGEVGPAG--SPGSNGAPGQRGEPGPQGHA 377
Query: 184 FGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSN 243
P G P G GG G G PG R G P G G
Sbjct: 378 GAQGPPGPPGINGSPGGKGEMGP--AGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPG 435
Query: 244 SGGGSG-----SQSGSSG----SGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG 294
G G + G +G G+ G++ S G + G + + G G +G
Sbjct: 436 KNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAG 495
Query: 295 --------------------GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGH--KPGCEK 332
G RG +G G G GS GG G KPG
Sbjct: 496 PNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPG 555
Query: 333 PGNEARGSGESGIQGFRGQ-------GVSSNMREISKEGNR----LLGGSGDNYRNSETS 381
E+ G G G RGQ G N K G R G G +N ET
Sbjct: 556 SQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETG 615
Query: 382 P 382
P
Sbjct: 616 P 616
Score = 63.5 bits (153), Expect = 3e-10
Identities = 69/234 (29%), Positives = 86/234 (36%), Gaps = 18/234 (7%)
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAGSFGMNPQG 190
+QG PG G SG G G+ G G G+ G G G P G PG G G P G
Sbjct: 199 YQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPG-PPGIKG--PAG 255
Query: 191 APWGQGGNGGPPNFGTNTQ-GAVAQPGYGSVRASNQNEGCTNPP-PSGSGGGSSNSG--G 246
P G G G N + G PG G P P G+ G G G
Sbjct: 256 IPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPG 315
Query: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSES 304
+G++ GS+G G + S G GS G++G G RG+ G +
Sbjct: 316 AAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQG 375
Query: 305 SWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNE----ARG----SGESGIQGFRG 350
G+ GS GG G PG ARG +G +G G RG
Sbjct: 376 HAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRG 429
Score = 55.8 bits (133), Expect = 7e-08
Identities = 73/248 (29%), Positives = 89/248 (35%), Gaps = 40/248 (16%)
Query: 124 GADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGS 183
GA+ + G +G PG G +G G G G G G PG G+P G G +
Sbjct: 984 GANGLSGE-RGPPGPQGLPGLAGTAGEPGRDGNPGSDGL--PGRDGSPGGKGDRGENGS- 1039
Query: 184 FGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPP-PSGSGGGSS 242
GAP G G+ GPP G V G R + G P P+GS G
Sbjct: 1040 -----PGAP-GAPGHPGPP-------GPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPG 1086
Query: 243 NSG-----GGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSG--GSSG--------GSSG 287
G G +G + + G G N + G G GS G G SG
Sbjct: 1087 PQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSG 1146
Query: 288 --GSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGES 343
G G SG G G G + G S H G G G PG PG G G +
Sbjct: 1147 PPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPG-PPGA--PGPCCGGVGAA 1203
Query: 344 GIQGFRGQ 351
I G G+
Sbjct: 1204 AIAGIGGE 1211
Score = 53.1 bits (126), Expect = 4e-07
Identities = 64/237 (27%), Positives = 79/237 (33%), Gaps = 18/237 (7%)
Query: 161 GQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSV 220
GQG G G P G PG + G+P G G + T Q Q V
Sbjct: 101 GQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDV 160
Query: 221 RASNQNEGCTN-PPPSGSGG--GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSS 277
++ G P P+G G G + G GS G G+ SG +
Sbjct: 161 KSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGA 220
Query: 278 SGGSSGGSSGGSSGNSG-----GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEK 332
G S G SG G G G G + G H G G NG K
Sbjct: 221 IGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGA 280
Query: 333 PGNEARGSGESGIQGFRGQGVSSNMREISKEGNR--LLGGSG----DNYRNSETSPG 383
PG + GE+G+ G G R E R L G +G D R S+ PG
Sbjct: 281 PGLK----GENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPG 333
Score = 49.3 bits (116), Expect = 6e-06
Identities = 48/175 (27%), Positives = 60/175 (34%), Gaps = 22/175 (12%)
Query: 124 GADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAG 182
G RG G G GA +G G G QG G +G+ G G G G+PGN
Sbjct: 1059 GKSGDRGE-SGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNP-- 1115
Query: 183 SFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSS 242
GAP G+ GP QGA+ PG R G + PP G
Sbjct: 1116 -------GAP----GSPGP----AGQQGAIGSPGPAGPRGP---VGPSGPPGKDGTSGHP 1157
Query: 243 NSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSR 297
G G + GS G + G + G GG + GG +
Sbjct: 1158 GPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEK 1212
Score = 36.2 bits (82), Expect = 0.056
Identities = 26/79 (32%), Positives = 32/79 (40%), Gaps = 10/79 (12%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ-------GNPGGLGTPWVHGYPGNSAGSFGM 186
G PG +G TSG G G G G +G+ G+PG G P G PG G G
Sbjct: 1146 GPPGKDG---TSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGA 1202
Query: 187 NPQGAPWGQGGNGGPPNFG 205
G+ G P +G
Sbjct: 1203 AAIAGIGGEKAGGFAPYYG 1221
>gi|47132620 keratin 2 [Homo sapiens]
Length = 639
Score = 85.5 bits (210), Expect = 8e-17
Identities = 52/125 (41%), Positives = 64/125 (51%), Gaps = 13/125 (10%)
Query: 236 GSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGG 295
GSGG S+SGGG S S S GSG + G S GG S S G SGG SGG G+ GG
Sbjct: 520 GSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSI-SGGGYGSGGGSGGRYGSGGG 578
Query: 296 SRGDSGSESSWGSSTG---SSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQG 352
S+G S S +GS G S G+ GGS G G+ G G G S ++G G+
Sbjct: 579 SKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSG---------GGGSSSVKGSSGEA 629
Query: 353 VSSNM 357
S++
Sbjct: 630 FGSSV 634
Score = 79.3 bits (194), Expect = 6e-15
Identities = 54/130 (41%), Positives = 64/130 (49%), Gaps = 17/130 (13%)
Query: 196 GGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSS 255
GG+GG +G+ + GY S +S + G + GSGGG S SGGG GS GS
Sbjct: 519 GGSGG--------RGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSG 570
Query: 256 GSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSG 315
G +G GGS GS SGG G S GG + GGSRG S S +GS G SS
Sbjct: 571 GRYGSG--------GGSKGGSISGGGYG-SGGGKHSSGGGSRGGSSSGGGYGSGGGGSSS 621
Query: 316 NHGGSGGGNG 325
G SG G
Sbjct: 622 VKGSSGEAFG 631
Score = 71.2 bits (173), Expect = 2e-12
Identities = 52/142 (36%), Positives = 64/142 (45%), Gaps = 13/142 (9%)
Query: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
SS S++ GSG G ++ G S GSSS SGG GS GGS G S G
Sbjct: 505 SSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSS-YGSGGRQSGSRGGSGGGGSISGGGY 563
Query: 301 GSESSWGSSTGSSSGNHGG--SGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMR 358
GS G GS G+ GG SGGG G G G +RG SG G G SS+++
Sbjct: 564 GSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSSSVK 623
Query: 359 EISKEGNRLLGGSGDNYRNSET 380
G SG+ + +S T
Sbjct: 624 ----------GSSGEAFGSSVT 635
Score = 65.5 bits (158), Expect = 9e-11
Identities = 55/147 (37%), Positives = 65/147 (44%), Gaps = 38/147 (25%)
Query: 155 GGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQ 214
GG GG+G + GG + G+S+ G G+ G GG G +++
Sbjct: 519 GGSGGRGSSSGGGYSS-------GSSSYGSGGRQSGSRGGSGGGG-----------SISG 560
Query: 215 PGYGSVRASNQNEGCTNPPPSGSGGGS---SNSGGGSGSQSGSSGSGSNGDNNNGSSSGG 271
GYGS S G SGGGS S SGGG GS G SG G S GG
Sbjct: 561 GGYGSGGGSGGRYG--------SGGGSKGGSISGGGYGSGGGKHSSG-------GGSRGG 605
Query: 272 SSSGSSSGGSSGGSSG--GSSGNSGGS 296
SSSG G GGSS GSSG + GS
Sbjct: 606 SSSGGGYGSGGGGSSSVKGSSGEAFGS 632
Score = 60.1 bits (144), Expect = 4e-09
Identities = 55/168 (32%), Positives = 68/168 (40%), Gaps = 24/168 (14%)
Query: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG 253
G+GG GG G ++ AV G R S + C + GGG GGG GS+S
Sbjct: 11 GRGGGGGGFR-GFSSGSAVVS---GGSRRSTSSFSCLS---RHGGGGGGFGGGGFGSRSL 63
Query: 254 SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSS 313
GG+ S S S GG G ++G GG G G SS+G +G S
Sbjct: 64 VG-------------LGGTKSISISVAGGGGGFG-AAGGFGGRGGGFGGGSSFGGGSGFS 109
Query: 314 SGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREIS 361
G GG G G G G PG G G GF G + E+S
Sbjct: 110 GGGFGGGGFGGGRFGGFGGPGGV---GGLGGPGGFGPGGYPGGIHEVS 154
Score = 53.1 bits (126), Expect = 4e-07
Identities = 43/121 (35%), Positives = 54/121 (44%), Gaps = 14/121 (11%)
Query: 137 GHNGAWETSGGHGIFGSQG-GLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQ 195
G G +SGG GS G GG+ G+ GG G G S G G G+
Sbjct: 520 GSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGG-------GGSISGGGYGSGGGSGGR 572
Query: 196 GGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSS 255
G+GG G+ + G GYGS + + G + S SGGG + GGGS S GSS
Sbjct: 573 YGSGGGSKGGSISGG-----GYGSGGGKHSSGGGSRGG-SSSGGGYGSGGGGSSSVKGSS 626
Query: 256 G 256
G
Sbjct: 627 G 627
Score = 50.4 bits (119), Expect = 3e-06
Identities = 48/152 (31%), Positives = 55/152 (36%), Gaps = 7/152 (4%)
Query: 156 GLGGQGQGNPG-GLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQ 214
G GG G G G G+ V G S SF + G G GG G ++ V
Sbjct: 11 GRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGG----GFGSRSLVGL 66
Query: 215 PGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGS--GSQSGSSGSGSNGDNNNGSSSGGS 272
G S+ S G G GG GGGS G SG SG G G G GG
Sbjct: 67 GGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGF 126
Query: 273 SSGSSSGGSSGGSSGGSSGNSGGSRGDSGSES 304
GG G G G GG S ++S
Sbjct: 127 GGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQS 158
Score = 46.6 bits (109), Expect = 4e-05
Identities = 27/66 (40%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Query: 145 SGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQ-----GAPWGQGGNG 199
+GG G FG+ GG GG+G G GG G+ G G G G P G GG G
Sbjct: 77 AGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLG 136
Query: 200 GPPNFG 205
GP FG
Sbjct: 137 GPGGFG 142
Score = 41.2 bits (95), Expect = 0.002
Identities = 40/106 (37%), Positives = 43/106 (40%), Gaps = 9/106 (8%)
Query: 254 SSGSGSNGDNNNGSSSG-----GSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWG- 307
S G G G G SSG G S S+S S GG G GG G GS S G
Sbjct: 9 SRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGG--GGFGSRSLVGL 66
Query: 308 SSTGSSSGNHGGSGGGNGHKPGC-EKPGNEARGSGESGIQGFRGQG 352
T S S + G GGG G G + G GS G GF G G
Sbjct: 67 GGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGG 112
Score = 39.3 bits (90), Expect = 0.007
Identities = 48/180 (26%), Positives = 55/180 (30%), Gaps = 37/180 (20%)
Query: 15 CLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQG 74
C G G G G + G A+ G G S + + GG G G G
Sbjct: 7 CKSRGRGG---GGGGFRGFSSGSAVVSG-GSRRSTSSFSCLSRHGGGGGG------FGGG 56
Query: 75 TREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQG 134
G G R + G G ++ V G G GR
Sbjct: 57 -----GFGSRSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGG----------------- 94
Query: 135 VPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWG 194
G G GG G G G GG G G GG G P G G G G P G P G
Sbjct: 95 --GFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGP---GGVGGLGGPGGFGPGGYPGG 149
Score = 35.8 bits (81), Expect = 0.074
Identities = 27/88 (30%), Positives = 35/88 (39%), Gaps = 7/88 (7%)
Query: 272 SSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCE 331
S GG GG G SSG++ S G S SS+ + G G GGG G +
Sbjct: 6 SCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVG 65
Query: 332 KPGNEA-------RGSGESGIQGFRGQG 352
G ++ G G GF G+G
Sbjct: 66 LGGTKSISISVAGGGGGFGAAGGFGGRG 93
Score = 34.7 bits (78), Expect = 0.16
Identities = 39/146 (26%), Positives = 53/146 (36%), Gaps = 30/146 (20%)
Query: 38 ALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGN 97
A G G S G G + G + G+ G + G G ++ G G+G+ G
Sbjct: 517 AFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGG-----GYGSGGGSGG 571
Query: 98 RVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGL 157
R G + G + + G G G G +SGG GS G
Sbjct: 572 RYGSGGGSKGGS------------------ISG---GGYGSGGGKHSSGGGSRGGSSSG- 609
Query: 158 GGQGQGNPGGLGTPWVHGYPGNSAGS 183
GG G G G G+ V G G + GS
Sbjct: 610 GGYGSG---GGGSSSVKGSSGEAFGS 632
Score = 28.9 bits (63), Expect = 9.0
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 9/87 (10%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSE-ALGQGT 75
GSG G + G G G G G G G G +GG GS + + G G+
Sbjct: 551 GSGGGGSISGG--------GYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGS 602
Query: 76 REAVGTGVRQVPGFGAADALGNRVGEA 102
R +G G G + ++ GEA
Sbjct: 603 RGGSSSGGGYGSGGGGSSSVKGSSGEA 629
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 80.9 bits (198), Expect = 2e-15
Identities = 68/216 (31%), Positives = 80/216 (37%), Gaps = 26/216 (12%)
Query: 118 EDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYP 177
ED G D + G G+ G GG G G +GG GG G G GY
Sbjct: 382 EDSRPSGGDFRGRGYGGERGYRGR----GGRG--GDRGGYGGDRSGGGYGGDRSSGGGYS 435
Query: 178 GN-SAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSG 236
G+ S G +G + G +G GG +G + G GYG R
Sbjct: 436 GDRSGGGYGGDRSGGGYGGDRGGG---YGGDRGG-----GYGGDRGGGYG--------GD 479
Query: 237 SGGGSSNSGGGSGSQSGSSGS---GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNS 293
GG + GGG G G G G GD G G S G GG GG SG
Sbjct: 480 RGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYG 539
Query: 294 GGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPG 329
G G G + S G G G +GG GG G K G
Sbjct: 540 GDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMG 575
Score = 75.1 bits (183), Expect = 1e-13
Identities = 72/248 (29%), Positives = 84/248 (33%), Gaps = 35/248 (14%)
Query: 147 GHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGM-----------------NPQ 189
G G + +GG G+G G WV P S G+ P
Sbjct: 333 GRGGYRGRGGFQGRGGDPKSG---DWV--CPNPSCGNMNFARRNSCNQCNEPRPEDSRPS 387
Query: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
G + G GG + + GYG R+ G SGGG S G G
Sbjct: 388 GGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGG-----DRSSGGGYSGDRSGGG 442
Query: 250 SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGD--SGSESSWG 307
SG G GD G G G GG GG GG G GG RG G +G
Sbjct: 443 YGGDRSGGGYGGDRGGGY---GGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYG 499
Query: 308 SSTGSSSGNHGGSGGGNGHKPGCEKPGNEA--RGSGESGIQGFRGQGVSSNMREISKEGN 365
G G+ GG GG G G G RG G SG G R G + G+
Sbjct: 500 GDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGG-SGYGGDRSGGYGGDRSGGGYGGD 558
Query: 366 RLLGGSGD 373
R G GD
Sbjct: 559 RGGGYGGD 566
Score = 73.9 bits (180), Expect = 2e-13
Identities = 61/198 (30%), Positives = 71/198 (35%), Gaps = 22/198 (11%)
Query: 130 GSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN-SAGSFGMNP 188
G +G G G GG+G S GG GG G G GY G+ S G +G +
Sbjct: 397 GGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDR 456
Query: 189 QGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGS 248
G G G G +G + G GYG R + GGG GG
Sbjct: 457 GGGYGGDRGGG----YGGDRGG-----GYGGDRGGYGGD---------RGGGYGGDRGGY 498
Query: 249 GSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSG---GSSGNSGGSRGDSGSESS 305
G G G G + GG S GG GG SG SG GG R G
Sbjct: 499 GGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGD 558
Query: 306 WGSSTGSSSGNHGGSGGG 323
G G G +GG GG
Sbjct: 559 RGGGYGGDRGGYGGKMGG 576
Score = 72.0 bits (175), Expect = 9e-13
Identities = 58/188 (30%), Positives = 73/188 (38%), Gaps = 15/188 (7%)
Query: 122 RHGADAVRGSWQGVP---GHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPG 178
R G RG + G G+ G + GG+ S GG GG G GG G GY G
Sbjct: 405 RGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG--GGYGGDRGGGYGG 462
Query: 179 NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG 238
+ G +G + G G GG+ G +G + G GYG R + G
Sbjct: 463 DRGGGYGGDRGG---GYGGDRG--GYGGDRGG-----GYGGDRGGYGGDRGGYGGDRGGY 512
Query: 239 GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
GG GG S+ G G G G SGG S GG G GG G+ GG G
Sbjct: 513 GGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGG 572
Query: 299 DSGSESSW 306
G + +
Sbjct: 573 KMGGRNDY 580
Score = 69.7 bits (169), Expect = 5e-12
Identities = 68/212 (32%), Positives = 82/212 (38%), Gaps = 41/212 (19%)
Query: 147 GHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGT 206
G G G +G G G+G G GY G+ +G GG GG + G
Sbjct: 393 GRGYGGERGYRGRGGRGGDRG-------GYGGDRSG-------------GGYGGDRSSGG 432
Query: 207 NTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNN- 265
G + GYG R+ G GG + GGG G G G G GD
Sbjct: 433 GYSGDRSGGGYGGDRSGGGYGG------DRGGGYGGDRGGGYG---GDRGGGYGGDRGGY 483
Query: 266 GSSSGGSSSGSSSG-----GSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGG- 319
G GG G G G GG GG G+ GG GD S +G G SG +GG
Sbjct: 484 GGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDR-SRGGYGGDRGGGSG-YGGD 541
Query: 320 -SGGGNGHKPGCEKPGNEARGSGESGIQGFRG 350
SGG G + G G+ RG G G +G G
Sbjct: 542 RSGGYGGDRSGGGYGGD--RGGGYGGDRGGYG 571
Score = 68.6 bits (166), Expect = 1e-11
Identities = 64/238 (26%), Positives = 82/238 (34%), Gaps = 32/238 (13%)
Query: 178 GNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE--GCTNPPPS 235
G+ G G G G GG P G P G++ + +N C P P
Sbjct: 326 GSGGGRRGRGGYRGRGGFQGRGGDPKSG---DWVCPNPSCGNMNFARRNSCNQCNEPRPE 382
Query: 236 ---------------------GSGGGSSNSGGGSGSQSGSS--GSGSNGDNNNGSSSGGS 272
G GG + GG G +SG G S+G +G SGG
Sbjct: 383 DSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGG 442
Query: 273 SSGSSSGGSSGGSSGGSSG--NSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGC 330
G SGG GG GG G GG GD G +G G G+ GG GG+ G
Sbjct: 443 YGGDRSGGGYGGDRGGGYGGDRGGGYGGDRG--GGYGGDRGGYGGDRGGGYGGDRGGYGG 500
Query: 331 EKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRNSETSPGMFNFD 388
++ G G G +G G S + G GG + S G + D
Sbjct: 501 DRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGD 558
Score = 52.4 bits (124), Expect = 8e-07
Identities = 65/248 (26%), Positives = 92/248 (37%), Gaps = 50/248 (20%)
Query: 152 GSQGGLGGQGQ-----GNPGGLG----TPWVHGYPGNSAGSFGMNPQG-APWGQGGNGGP 201
GS G GG+ Q GNPG G + GY + S+G N G + +GQ +
Sbjct: 5 GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSY 64
Query: 202 PNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG--------------SSNSGGG 247
+ Q + +Q Y +NQ + N SGS GG S + G
Sbjct: 65 GGYENQKQSSYSQQPY-----NNQGQQ-QNMESSGSQGGRAPSYDQPDYGQQDSYDQQSG 118
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSS--------------GGSSGGSSGNS 293
GS SN D + S S S S + G + G G+
Sbjct: 119 YDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQ 178
Query: 294 GGSRGDSGSESSW-GSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESG----IQGF 348
GG RG G + G TGSS G+ GG GH+ + ++ +QG
Sbjct: 179 GGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGL 238
Query: 349 RGQGVSSN 356
G+GVS++
Sbjct: 239 -GEGVSTD 245
Score = 50.4 bits (119), Expect = 3e-06
Identities = 54/178 (30%), Positives = 69/178 (38%), Gaps = 14/178 (7%)
Query: 36 GEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFG---AA 92
G+ G G G S G G + + GG G + G G G G + G+G
Sbjct: 417 GDRSGGGYGGDRSSGGGYSGDRSGGGYGGDR--SGGGYGGDRGGGYGGDRGGGYGGDRGG 474
Query: 93 DALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFG 152
G+R G G G + G D +G D RG + G G G + GG+G G
Sbjct: 475 GYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGD--RGGYGGDRGGYGGDRSRGGYG--G 530
Query: 153 SQGGLGGQGQGNPGGLGTPWV-HGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQ 209
+GG G G GG G GY G+ G +G G G GG G N N Q
Sbjct: 531 DRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYG----GDRGGYGGKMGGRNDYRNDQ 584
Score = 47.4 bits (111), Expect = 2e-05
Identities = 50/160 (31%), Positives = 55/160 (34%), Gaps = 44/160 (27%)
Query: 230 TNPPPSGSGGGSSNSGGGSGSQSGSSG-SGSNGDNNNGS--------------------- 267
T P GGGS G G G G G GD +G
Sbjct: 316 TRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQ 375
Query: 268 ----------SSGGSSSGSSSGGSSG----GSSGGSSGNSGGSR---GDSGSESSWGSST 310
SGG G GG G G GG G GG R G G SS G +
Sbjct: 376 CNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYS 435
Query: 311 GS-SSGNHGG--SGGGNGHKPGCEKPGNEARGSGESGIQG 347
G S G +GG SGGG G G G+ RG G G +G
Sbjct: 436 GDRSGGGYGGDRSGGGYGGDRGGGYGGD--RGGGYGGDRG 473
Score = 37.4 bits (85), Expect = 0.025
Identities = 32/145 (22%), Positives = 55/145 (37%), Gaps = 2/145 (1%)
Query: 269 SGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKP 328
S S G S G S+ G+ G+ G + S S S +G +T SS G + G
Sbjct: 2 SDSGSYGQSGGEQQSYSTYGNPGSQGYGQA-SQSYSGYGQTTDSSYGQNYSGYSSYGQSY 60
Query: 329 GCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRNSETSPGMFNFD 388
G E + Q + QG NM +G R +Y ++ +D
Sbjct: 61 SQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYD 120
Query: 389 TFWKNFKSKLGF-INWDAINKDQRS 412
++ + + D+ +++Q+S
Sbjct: 121 QHQGSYDEQSNYDQQHDSYSQNQQS 145
Score = 36.6 bits (83), Expect = 0.043
Identities = 35/119 (29%), Positives = 46/119 (38%), Gaps = 18/119 (15%)
Query: 283 GGSSGGSSGNSGGSRGDSGSESSWGSSTGS-------SSGN-----HGGSGGGNGHKPGC 330
GG SGG GG RG G + G S GN N +P
Sbjct: 324 GGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPED 383
Query: 331 EKP-GNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRNSETSPGMFNFD 388
+P G + RG G G +G+RG+G R G+R SG Y +S G ++ D
Sbjct: 384 SRPSGGDFRGRGYGGERGYRGRGGRGGDRG-GYGGDR----SGGGYGGDRSSGGGYSGD 437
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 80.9 bits (198), Expect = 2e-15
Identities = 68/216 (31%), Positives = 80/216 (37%), Gaps = 26/216 (12%)
Query: 118 EDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYP 177
ED G D + G G+ G GG G G +GG GG G G GY
Sbjct: 385 EDSRPSGGDFRGRGYGGERGYRGR----GGRG--GDRGGYGGDRSGGGYGGDRSSGGGYS 438
Query: 178 GN-SAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSG 236
G+ S G +G + G +G GG +G + G GYG R
Sbjct: 439 GDRSGGGYGGDRSGGGYGGDRGGG---YGGDRGG-----GYGGDRGGGYG--------GD 482
Query: 237 SGGGSSNSGGGSGSQSGSSGS---GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNS 293
GG + GGG G G G G GD G G S G GG GG SG
Sbjct: 483 RGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYG 542
Query: 294 GGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPG 329
G G G + S G G G +GG GG G K G
Sbjct: 543 GDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMG 578
Score = 75.1 bits (183), Expect = 1e-13
Identities = 72/248 (29%), Positives = 84/248 (33%), Gaps = 35/248 (14%)
Query: 147 GHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGM-----------------NPQ 189
G G + +GG G+G G WV P S G+ P
Sbjct: 336 GRGGYRGRGGFQGRGGDPKSG---DWV--CPNPSCGNMNFARRNSCNQCNEPRPEDSRPS 390
Query: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
G + G GG + + GYG R+ G SGGG S G G
Sbjct: 391 GGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGG-----DRSSGGGYSGDRSGGG 445
Query: 250 SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGD--SGSESSWG 307
SG G GD G G G GG GG GG G GG RG G +G
Sbjct: 446 YGGDRSGGGYGGDRGGGY---GGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYG 502
Query: 308 SSTGSSSGNHGGSGGGNGHKPGCEKPGNEA--RGSGESGIQGFRGQGVSSNMREISKEGN 365
G G+ GG GG G G G RG G SG G R G + G+
Sbjct: 503 GDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGG-SGYGGDRSGGYGGDRSGGGYGGD 561
Query: 366 RLLGGSGD 373
R G GD
Sbjct: 562 RGGGYGGD 569
Score = 73.9 bits (180), Expect = 2e-13
Identities = 61/198 (30%), Positives = 71/198 (35%), Gaps = 22/198 (11%)
Query: 130 GSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN-SAGSFGMNP 188
G +G G G GG+G S GG GG G G GY G+ S G +G +
Sbjct: 400 GGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDR 459
Query: 189 QGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGS 248
G G G G +G + G GYG R + GGG GG
Sbjct: 460 GGGYGGDRGGG----YGGDRGG-----GYGGDRGGYGGD---------RGGGYGGDRGGY 501
Query: 249 GSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSG---GSSGNSGGSRGDSGSESS 305
G G G G + GG S GG GG SG SG GG R G
Sbjct: 502 GGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGD 561
Query: 306 WGSSTGSSSGNHGGSGGG 323
G G G +GG GG
Sbjct: 562 RGGGYGGDRGGYGGKMGG 579
Score = 72.0 bits (175), Expect = 9e-13
Identities = 58/188 (30%), Positives = 73/188 (38%), Gaps = 15/188 (7%)
Query: 122 RHGADAVRGSWQGVP---GHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPG 178
R G RG + G G+ G + GG+ S GG GG G GG G GY G
Sbjct: 408 RGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG--GGYGGDRGGGYGG 465
Query: 179 NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG 238
+ G +G + G G GG+ G +G + G GYG R + G
Sbjct: 466 DRGGGYGGDRGG---GYGGDRG--GYGGDRGG-----GYGGDRGGYGGDRGGYGGDRGGY 515
Query: 239 GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
GG GG S+ G G G G SGG S GG G GG G+ GG G
Sbjct: 516 GGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGG 575
Query: 299 DSGSESSW 306
G + +
Sbjct: 576 KMGGRNDY 583
Score = 69.7 bits (169), Expect = 5e-12
Identities = 68/212 (32%), Positives = 82/212 (38%), Gaps = 41/212 (19%)
Query: 147 GHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGT 206
G G G +G G G+G G GY G+ +G GG GG + G
Sbjct: 396 GRGYGGERGYRGRGGRGGDRG-------GYGGDRSG-------------GGYGGDRSSGG 435
Query: 207 NTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNN- 265
G + GYG R+ G GG + GGG G G G G GD
Sbjct: 436 GYSGDRSGGGYGGDRSGGGYGG------DRGGGYGGDRGGGYG---GDRGGGYGGDRGGY 486
Query: 266 GSSSGGSSSGSSSG-----GSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGG- 319
G GG G G G GG GG G+ GG GD S +G G SG +GG
Sbjct: 487 GGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDR-SRGGYGGDRGGGSG-YGGD 544
Query: 320 -SGGGNGHKPGCEKPGNEARGSGESGIQGFRG 350
SGG G + G G+ RG G G +G G
Sbjct: 545 RSGGYGGDRSGGGYGGD--RGGGYGGDRGGYG 574
Score = 68.6 bits (166), Expect = 1e-11
Identities = 64/238 (26%), Positives = 82/238 (34%), Gaps = 32/238 (13%)
Query: 178 GNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE--GCTNPPPS 235
G+ G G G G GG P G P G++ + +N C P P
Sbjct: 329 GSGGGRRGRGGYRGRGGFQGRGGDPKSG---DWVCPNPSCGNMNFARRNSCNQCNEPRPE 385
Query: 236 ---------------------GSGGGSSNSGGGSGSQSGSS--GSGSNGDNNNGSSSGGS 272
G GG + GG G +SG G S+G +G SGG
Sbjct: 386 DSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGG 445
Query: 273 SSGSSSGGSSGGSSGGSSG--NSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGC 330
G SGG GG GG G GG GD G +G G G+ GG GG+ G
Sbjct: 446 YGGDRSGGGYGGDRGGGYGGDRGGGYGGDRG--GGYGGDRGGYGGDRGGGYGGDRGGYGG 503
Query: 331 EKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRNSETSPGMFNFD 388
++ G G G +G G S + G GG + S G + D
Sbjct: 504 DRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGD 561
Score = 53.9 bits (128), Expect = 3e-07
Identities = 66/248 (26%), Positives = 92/248 (37%), Gaps = 47/248 (18%)
Query: 152 GSQGGLGGQGQ-----GNPGGLG----TPWVHGYPGNSAGSFGMNPQG-APWGQGGNGGP 201
GS G GG+ Q GNPG G + GY + S+G N G + +GQ +G
Sbjct: 5 GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYS 64
Query: 202 PNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG--------------SSNSGGG 247
++G Q Y +NQ + N SGS GG S + G
Sbjct: 65 QSYGGYENQK--QSSYSQQPYNNQGQQ-QNMESSGSQGGRAPSYDQPDYGQQDSYDQQSG 121
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSS--------------GGSSGGSSGNS 293
GS SN D + S S S S + G + G G+
Sbjct: 122 YDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQ 181
Query: 294 GGSRGDSGSESSW-GSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESG----IQGF 348
GG RG G + G TGSS G+ GG GH+ + ++ +QG
Sbjct: 182 GGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGL 241
Query: 349 RGQGVSSN 356
G+GVS++
Sbjct: 242 -GEGVSTD 248
Score = 50.4 bits (119), Expect = 3e-06
Identities = 54/178 (30%), Positives = 69/178 (38%), Gaps = 14/178 (7%)
Query: 36 GEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFG---AA 92
G+ G G G S G G + + GG G + G G G G + G+G
Sbjct: 420 GDRSGGGYGGDRSSGGGYSGDRSGGGYGGDR--SGGGYGGDRGGGYGGDRGGGYGGDRGG 477
Query: 93 DALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFG 152
G+R G G G + G D +G D RG + G G G + GG+G G
Sbjct: 478 GYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGD--RGGYGGDRGGYGGDRSRGGYG--G 533
Query: 153 SQGGLGGQGQGNPGGLGTPWV-HGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQ 209
+GG G G GG G GY G+ G +G G G GG G N N Q
Sbjct: 534 DRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYG----GDRGGYGGKMGGRNDYRNDQ 587
Score = 47.4 bits (111), Expect = 2e-05
Identities = 50/160 (31%), Positives = 55/160 (34%), Gaps = 44/160 (27%)
Query: 230 TNPPPSGSGGGSSNSGGGSGSQSGSSG-SGSNGDNNNGS--------------------- 267
T P GGGS G G G G G GD +G
Sbjct: 319 TRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQ 378
Query: 268 ----------SSGGSSSGSSSGGSSG----GSSGGSSGNSGGSR---GDSGSESSWGSST 310
SGG G GG G G GG G GG R G G SS G +
Sbjct: 379 CNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYS 438
Query: 311 GS-SSGNHGG--SGGGNGHKPGCEKPGNEARGSGESGIQG 347
G S G +GG SGGG G G G+ RG G G +G
Sbjct: 439 GDRSGGGYGGDRSGGGYGGDRGGGYGGD--RGGGYGGDRG 476
Score = 36.6 bits (83), Expect = 0.043
Identities = 35/119 (29%), Positives = 46/119 (38%), Gaps = 18/119 (15%)
Query: 283 GGSSGGSSGNSGGSRGDSGSESSWGSSTGS-------SSGN-----HGGSGGGNGHKPGC 330
GG SGG GG RG G + G S GN N +P
Sbjct: 327 GGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPED 386
Query: 331 EKP-GNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRNSETSPGMFNFD 388
+P G + RG G G +G+RG+G R G+R SG Y +S G ++ D
Sbjct: 387 SRPSGGDFRGRGYGGERGYRGRGGRGGDRG-GYGGDR----SGGGYGGDRSSGGGYSGD 440
Score = 32.3 bits (72), Expect = 0.81
Identities = 37/170 (21%), Positives = 58/170 (34%), Gaps = 24/170 (14%)
Query: 244 SGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303
S GS QSG + N GS G +S S SG S SG
Sbjct: 2 SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSG--------Y 53
Query: 304 SSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKE 363
SS+G S S ++G G E + Q + QG NM +
Sbjct: 54 SSYGQSQSGYSQSYG---------------GYENQKQSSYSQQPYNNQGQQQNMESSGSQ 98
Query: 364 GNRLLGGSGDNYRNSETSPGMFNFDTFWKNFKSKLGF-INWDAINKDQRS 412
G R +Y ++ +D ++ + + D+ +++Q+S
Sbjct: 99 GGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQS 148
>gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo
sapiens]
Length = 378
Score = 80.1 bits (196), Expect = 3e-15
Identities = 68/193 (35%), Positives = 82/193 (42%), Gaps = 31/193 (16%)
Query: 130 GSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQ 189
GS +G G +G + GG+ FG GG G+G GN GG G GY G GS G
Sbjct: 211 GSQRGRGGGSGNFMGRGGN--FGGGGGNFGRG-GNFGGRG-----GYGGGGGGSRGS--- 259
Query: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
+G GG+GG FG + PGY S G G G N GGG G
Sbjct: 260 ---YG-GGDGGYNGFGGDGGNYGGGPGYSSRGGYG-----------GGGPGYGNQGGGYG 304
Query: 250 SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSS 309
G G +G N G+ GG+ G + G SG N G +G S S GS
Sbjct: 305 G-----GGGYDGYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSP 359
Query: 310 TGSSSGNHGGSGG 322
G G+ GGSGG
Sbjct: 360 YGGGYGSGGGSGG 372
Score = 72.0 bits (175), Expect = 9e-13
Identities = 65/196 (33%), Positives = 81/196 (41%), Gaps = 37/196 (18%)
Query: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGA 211
GSQ G GG G GN G G G+FG G +G+GGN G +G
Sbjct: 211 GSQRGRGG-GSGNFMGRG------------GNFGGG--GGNFGRGGNFGG-------RGG 248
Query: 212 VAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG-SQSGSSGSGSNGDNNNGSSSG 270
G GS + +G N G GG N GGG G S G G G G N G G
Sbjct: 249 YGGGGGGSRGSYGGGDGGYN----GFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYG 304
Query: 271 GSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGN--GHKP 328
G GG G + GG+ G GG+ G G+ + +G+ +G N+G GG+ G
Sbjct: 305 G------GGGYDGYNEGGNFG--GGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSS 356
Query: 329 GCEKPGNEARGSGESG 344
G G G G G
Sbjct: 357 GSPYGGGYGSGGGSGG 372
Score = 65.9 bits (159), Expect = 7e-11
Identities = 44/125 (35%), Positives = 53/125 (42%), Gaps = 4/125 (3%)
Query: 237 SGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSS-GGSSGGSSGGSSGNSGG 295
S G GGGSG+ G G+ G N G GG+ G GG GGS G G GG
Sbjct: 209 SAGSQRGRGGGSGNFMGRGGNFGGGGGNFGR--GGNFGGRGGYGGGGGGSRGSYGGGDGG 266
Query: 296 SRGDSGSESSWGSSTG-SSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVS 354
G G ++G G SS G +GG G G G++ G G G E G G G
Sbjct: 267 YNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGG 326
Query: 355 SNMRE 359
N +
Sbjct: 327 GNYND 331
Score = 58.2 bits (139), Expect = 1e-08
Identities = 65/212 (30%), Positives = 84/212 (39%), Gaps = 37/212 (17%)
Query: 51 VGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTG 110
V KA+ K+ +AGS+ G G+ +G G G G GN G + G G
Sbjct: 198 VKKALSKQEMQSAGSQ--RGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGG 255
Query: 111 HEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGT 170
D +G G++ G PG++ GG +G+QGG G G GG
Sbjct: 256 SRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGG----GYGGGGG--- 308
Query: 171 PWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT 230
GY N G+FG G +G GGN +FG S Q +
Sbjct: 309 --YDGY--NEGGNFG----GGNYGGGGNYN--DFG---------------NYSGQQQSNY 343
Query: 231 NPPPSGSGGGSSNS---GGGSGSQSGSSGSGS 259
P GS GG S+ GGG GS GS G GS
Sbjct: 344 GPMKGGSFGGRSSGSPYGGGYGSGGGSGGYGS 375
Score = 57.4 bits (137), Expect = 2e-08
Identities = 43/129 (33%), Positives = 50/129 (38%), Gaps = 7/129 (5%)
Query: 251 QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSST 310
QS S G G + N GG+ G GG+ GG G GG GS S+G
Sbjct: 208 QSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGG---GGSRGSYGGGD 264
Query: 311 GSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ--GFRGQGVSSNMREISKEGNRLL 368
G +G GG GG G PG G G G Q G+ G G E G
Sbjct: 265 GGYNG-FGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGGGNY 323
Query: 369 GGSGDNYRN 377
GG G NY +
Sbjct: 324 GGGG-NYND 331
Score = 43.5 bits (101), Expect = 4e-04
Identities = 37/124 (29%), Positives = 47/124 (37%), Gaps = 20/124 (16%)
Query: 257 SGSNGDNNNGSSSGGSSSGSSSGGSSGGSSG--GSSGNSGGSRGDSGSESSWGSSTGSSS 314
+G N + S S S G GGS G GN GG G+ G ++G
Sbjct: 192 NGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGR----- 246
Query: 315 GNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVS-SNMREISKEGNRLLGGSGD 373
G +GG GGG+ + G G+ G GF G G + S G GG G
Sbjct: 247 GGYGGGGGGS----------RGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGG--YGGGGP 294
Query: 374 NYRN 377
Y N
Sbjct: 295 GYGN 298
>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
Length = 1745
Score = 79.7 bits (195), Expect = 4e-15
Identities = 101/350 (28%), Positives = 128/350 (36%), Gaps = 31/350 (8%)
Query: 19 GEAGPL-QSGEESTGTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGTR 76
G GP+ +G +G A G GL G + SEG G AG K S +G R
Sbjct: 998 GPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEG--------PVGPAGKKGS----RGER 1045
Query: 77 EAVG-TGVRQVPG----FGAADALGNRVGEAAHA-LGNTGHEIGRQAE-DVIRHGADAVR 129
G TG +PG G A G E +G GH+ + + D G +R
Sbjct: 1046 GPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIR 1105
Query: 130 G--SWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQ----GNPGGLGTPWVHGYPGNSAGS 183
G G PG +GA G G+FG +G G +G G PG G P G G
Sbjct: 1106 GPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDV 1165
Query: 184 FGMNPQGAPWGQGGNGGPPNFGT-NTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSS 242
M P GAP +G G + GT G V QPG + + G PP + G
Sbjct: 1166 GSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPK 1225
Query: 243 NSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDS 300
G G S +G G G S +G G G SG GS G+
Sbjct: 1226 GDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEK 1285
Query: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRG 350
G G + G+ G G + G E R GE G +G G
Sbjct: 1286 GDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGR-EGEKGAKGEPG 1334
Score = 63.5 bits (153), Expect = 3e-10
Identities = 90/341 (26%), Positives = 114/341 (33%), Gaps = 46/341 (13%)
Query: 66 KVSEALGQGTREAVG-TGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHG 124
K+ G R G TG + GF L G+ G+ GH +G+ G
Sbjct: 528 KMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQR----GDFGH-VGQPGPP----G 578
Query: 125 ADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSF 184
D RG+ +G PG G G G+ G +G +PG G P V G G
Sbjct: 579 EDGERGA-EGPPGPTGQAGEPGPRGLLGPRG--------SPGPTGRPGVTGIDGAPGAKG 629
Query: 185 GMNPQGAPW--GQGGNGGP-----PNFGTNTQGAVAQPGYGSVRASNQNEGCTNPP---- 233
+ P G P GQ GN G P T G PG + ++G P
Sbjct: 630 NVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEG 689
Query: 234 PSGSGG--GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSG 291
P+G G G S G G G++G+ G G G G
Sbjct: 690 PTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQG 749
Query: 292 NSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFR 349
G G RG+ G E G + + GS G G PG R G G GF
Sbjct: 750 KPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGR-PGPKGSIGFP 808
Query: 350 G-------QGVSSNMREISKEGNRLLGGSGDNYRNSETSPG 383
G +G S + EG R GS R PG
Sbjct: 809 GPLGPIGEKGKSGKTGQPGLEGERGPPGS----RGERGQPG 845
Score = 61.2 bits (147), Expect = 2e-09
Identities = 72/257 (28%), Positives = 88/257 (34%), Gaps = 36/257 (14%)
Query: 123 HGADAVRGSWQ--GVPGHNGAWETSGGHGIFGSQGGLGGQG----------QGNPGGLGT 170
HG+ + G G PG G G G+ GS G LG G QG PG G
Sbjct: 646 HGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGP 705
Query: 171 PWVHGYPGNSA--GSFGMNPQGAPWGQGGNGGPPNF--GTNTQGAVAQPGYGSVRASNQN 226
P GYPG G+ G G+ G G P F +G +PG R +
Sbjct: 706 P---GYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGP 762
Query: 227 EGCTNPPPSGSGGGSSNSG-GGSGSQSGSSG-------SGSNGDNNNGSSSGGSSSGSSS 278
EG P G G + G GS + G G G G + G
Sbjct: 763 EG-----PKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEK 817
Query: 279 GGSSGGSSGGSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK--PGCEKPG 334
G S G G G GSRG+ G + G G+ G G K PG + P
Sbjct: 818 GKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPP 877
Query: 335 NEARGSGESGIQGFRGQ 351
G G QG G+
Sbjct: 878 GFPGPKGPPGHQGKDGR 894
Score = 58.9 bits (141), Expect = 8e-09
Identities = 81/307 (26%), Positives = 103/307 (33%), Gaps = 35/307 (11%)
Query: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
G AG E E GV +PG+ +G LG G E G+ +
Sbjct: 767 GQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPG-PLGPIG-EKGKSGKT- 823
Query: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGN 179
G + G +G PG G G G G +G +G G G PG G P + G PG
Sbjct: 824 ---GQPGLEGE-RGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGF 879
Query: 180 SAGSFGMNPQGAPWGQGGNGGPPNFG----TNTQGAVAQPGYGSVRASNQNEGCTNP--- 232
P+G P QG +G P + G QG PG V G P
Sbjct: 880 PG------PKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGE 933
Query: 233 --PPSGSGGGSSNSGGGSGSQSGSSGS-GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGS 289
PP G G + G+ G G G +G GG G
Sbjct: 934 RGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGL 993
Query: 290 SGNSG-----GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARG----S 340
G+ G G+ G G G + G GS G G P +K RG +
Sbjct: 994 KGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVG--PAGKKGSRGERGPPGPT 1051
Query: 341 GESGIQG 347
G+ GI G
Sbjct: 1052 GKDGIPG 1058
Score = 57.0 bits (136), Expect = 3e-08
Identities = 76/271 (28%), Positives = 96/271 (35%), Gaps = 33/271 (12%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQG-QGNPGGLGTPWVHGYPGNSAGSFGMNPQGAP 192
G+PGH G G G G QG G QG G PG +G G PG + G+ G+ P
Sbjct: 494 GLPGHPG---LKGEEGAEGPQGPRGLQGPHGPPGRVGK---MGRPG-ADGARGLPGDTGP 546
Query: 193 WGQGGNGGPPNF-GTNTQ----GAVAQPGYGSVRASNQNEGCTNPPPSGSGG-------- 239
G G G P G Q G V QPG EG P P+G G
Sbjct: 547 KGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEG--PPGPTGQAGEPGPRGLL 604
Query: 240 GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSR 297
G S G +G + G+ G N G G G G G G +
Sbjct: 605 GPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEK 664
Query: 298 GDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRG----QGV 353
G G+ G H G G G K G + P A G G +G +G +G+
Sbjct: 665 GPPGNPGIPGLPGSDGPLGHPGHEGPTGEK-GAQGPPGSAGPPGYPGPRGVKGTSGNRGL 723
Query: 354 SSNMREISKEGNRLLGGSGD-NYRNSETSPG 383
E ++G G GD + + PG
Sbjct: 724 QGEKGEKGEDG--FPGFKGDVGLKGDQGKPG 752
Score = 55.5 bits (132), Expect = 9e-08
Identities = 80/289 (27%), Positives = 100/289 (34%), Gaps = 32/289 (11%)
Query: 131 SWQGVPGHNGAWETSGGHGIFGSQGGLGGQG-QGNPGGLGTPWVHGYPGNSAGSFGMNPQ 189
S +G PG G G G+ G G G +G +G G G HG PG +
Sbjct: 476 SMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGR------VGKM 529
Query: 190 GAPWGQGGNGGP----PNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSG 245
G P G G P P G PG R + G PP G+
Sbjct: 530 GRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPP 589
Query: 246 GGSGSQSGSSG-------SGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GS 296
G +G Q+G G GS G +G + + G G G G GS
Sbjct: 590 GPTG-QAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGS 648
Query: 297 RGDSGSESSWGS-STGSSSGNHG-----GSGGGNGHKPGCEKPGNEARGSGESGIQGFRG 350
+G G + G+ GN G GS G GH PG E P E G G G G
Sbjct: 649 QGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGH-PGHEGPTGEKGAQGPPGSAGPPG 707
Query: 351 QGVSSNMREISKEGNRLLGGSGDNYRNSETSPGMFNFDTFWKNFKSKLG 399
++ S GNR L G + + PG F D K + K G
Sbjct: 708 YPGPRGVKGTS--GNRGLQGE-KGEKGEDGFPG-FKGDVGLKGDQGKPG 752
Score = 52.4 bits (124), Expect = 8e-07
Identities = 49/163 (30%), Positives = 66/163 (40%), Gaps = 15/163 (9%)
Query: 122 RHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQG-QGNPGGLGTPWVHGYPGNS 180
R G + +G+ +G PG +G +G G G G +G +G +G PG +G P + G PG
Sbjct: 1320 REGREGEKGA-KGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQM 1378
Query: 181 AGSFGMNPQGAPWGQGGNGGPPNFG-TNTQGAVAQPGYGSVRASNQNEGCTNPP-PSGSG 238
+ P G P +G G G G + PG + G PP P G
Sbjct: 1379 GPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDP 1438
Query: 239 G-----GSSNSGGGSG-----SQSGSSGS-GSNGDNNNGSSSG 270
G GS G G Q GS GS GS G + +G
Sbjct: 1439 GPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAG 1481
Score = 47.0 bits (110), Expect = 3e-05
Identities = 67/250 (26%), Positives = 75/250 (30%), Gaps = 38/250 (15%)
Query: 124 GADAVRGSW--QGVPGHNGAWETSGGHGIFGSQGGLGGQGQ----GNPGGLGTPWVHGYP 177
G D +GS G+PG G G GI GS G G G G PG G P G P
Sbjct: 1250 GEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPP 1309
Query: 178 GNSAGSFGMNPQG-----------APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQN 226
G S M +G P G G GP G V G +
Sbjct: 1310 GKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMG-ARGPPGRVGPEGLRGI------ 1362
Query: 227 EGCTNPPPSGSGG--GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGG 284
P P G G G+ G G S G GD G G
Sbjct: 1363 -----PGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEA 1417
Query: 285 SSGGSSGNSG-----GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK--PGCEKPGNEA 337
G G G G +GD G GS G G G K PG P +
Sbjct: 1418 GEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDT 1477
Query: 338 RGSGESGIQG 347
+G G G
Sbjct: 1478 GPAGPPGPPG 1487
Score = 45.4 bits (106), Expect = 9e-05
Identities = 61/225 (27%), Positives = 74/225 (32%), Gaps = 12/225 (5%)
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL-GTPWVHGYPGNSAGSFGMNPQG 190
++G PG G G G G G G G P GL G P + G G M Q
Sbjct: 390 FEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQF 449
Query: 191 APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT-NPPPSGSGG--GSSNSGGG 247
A G G P +F AV Q S++ G T P P G G G G
Sbjct: 450 A--GGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGA 507
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESS 305
G Q G +G G + + G G G G G G+ G
Sbjct: 508 EGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGD 567
Query: 306 WGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRG 350
+G G G G PG P +A G G+ G RG
Sbjct: 568 FGHVGQPGPPGEDGERGAEG-PPG---PTGQAGEPGPRGLLGPRG 608
Score = 40.4 bits (93), Expect = 0.003
Identities = 54/202 (26%), Positives = 67/202 (33%), Gaps = 28/202 (13%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ----GNPGGLGTPWVHGYPGNSAGSFGMNPQ 189
G PG G SG G G +G G +G+ G PG G G PG G G+
Sbjct: 1304 GAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGR-VGPEGLRGI 1362
Query: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGG---------- 239
P G+ G G P G + PG +G T P G G
Sbjct: 1363 PGPVGEPGLLGAP-------GQMGPPGPLGPSGLPGLKGDTG--PKGEKGHIGLIGLIGP 1413
Query: 240 -GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GS 296
G + G G G GD G G + GS G+ G G
Sbjct: 1414 PGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGP 1473
Query: 297 RGDSGSESSWGSSTGSSSGNHG 318
RGD+G G G+ + HG
Sbjct: 1474 RGDTGPAGPPG-PPGAPAELHG 1494
Score = 32.7 bits (73), Expect = 0.62
Identities = 25/78 (32%), Positives = 30/78 (38%), Gaps = 6/78 (7%)
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAP 192
QG+PG G G G G G +G G P G+ P G G+ M P+G
Sbjct: 1423 QGLPGVQGP---PGPKGDPGPPGPIGSLGHPGPPGVAGPL--GQKGSKGSPGSMGPRG-D 1476
Query: 193 WGQGGNGGPPNFGTNTQG 210
G G GPP G
Sbjct: 1477 TGPAGPPGPPGAPAELHG 1494
>gi|48762934 alpha 2 type I collagen [Homo sapiens]
Length = 1366
Score = 78.2 bits (191), Expect = 1e-14
Identities = 88/316 (27%), Positives = 112/316 (35%), Gaps = 35/316 (11%)
Query: 73 QGTREAVGT----GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAV 128
QG R GT G + + G D L + G A G G E G E+ G
Sbjct: 162 QGARGFPGTPGLPGFKGIRGHNGLDGLKGQPG----APGVKG-EPGAPGEN----GTPGQ 212
Query: 129 RGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNP-GGLGTPWVHGYPG-----NSAG 182
G+ +G+PG G G G GS G +G G P G G P G PG + G
Sbjct: 213 TGA-RGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVG 271
Query: 183 SFGMNPQGAPWGQ------GGNGGPP-----NFGTNTQGAVAQPGYGSVRASNQNEGCTN 231
+ G P G+ G GPP N T +GA PG G
Sbjct: 272 NAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPG 331
Query: 232 PPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSG 291
P + G+ G G SG+ G+ + G G GS+G
Sbjct: 332 PVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAG 391
Query: 292 NSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFR 349
G G RG GS G+ + GS G +G G P +A GE G+ G R
Sbjct: 392 PPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASG-PAGVRGPNGDAGRPGEPGLMGPR 450
Query: 350 G-QGVSSNMREISKEG 364
G G N+ KEG
Sbjct: 451 GLPGSPGNIGPAGKEG 466
Score = 72.0 bits (175), Expect = 9e-13
Identities = 100/336 (29%), Positives = 121/336 (36%), Gaps = 53/336 (15%)
Query: 47 LSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGT-GVRQVPG-FGAADALGNR--VGEA 102
LS VG A G G+K + L G A G G R +PG GAA A G R VGE
Sbjct: 290 LSGPVGPPGNPGANGLTGAKGAAGL-PGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEP 348
Query: 103 AHALGNTGHEIGRQAE--------------DVIRHGADAVRGSWQGVPGHNGAWETSGGH 148
A G+ G E G + E + + G + GS G PG G + G
Sbjct: 349 GPA-GSKG-ESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGS-AGPPGPPGLRGSPGSR 405
Query: 149 GIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAGSFG----MNPQGAPWGQGGNGGPPN 203
G+ G+ G G G G+ G G V G P AG G M P+G P G GN GP
Sbjct: 406 GLPGADGRAGVMGPPGSRGASGPAGVRG-PNGDAGRPGEPGLMGPRGLP-GSPGNIGP-- 461
Query: 204 FGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSG--GGSGSQSGSSGSGSNG 261
+G V PG P P G G G G G + + G NG
Sbjct: 462 --AGKEGPVGLPGIDG-----------RPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNG 508
Query: 262 DNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGG 319
D + +G + G + G G G G +G G G S G
Sbjct: 509 DKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVG 568
Query: 320 SGGGNG-----HKPGCEKPGNEARGSGESGIQGFRG 350
G G PG P E GESG G G
Sbjct: 569 KPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTG 604
Score = 68.9 bits (167), Expect = 8e-12
Identities = 84/295 (28%), Positives = 112/295 (37%), Gaps = 27/295 (9%)
Query: 82 GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGA 141
G R PG A +G + G G + + V+ A G+PG GA
Sbjct: 589 GERGPPGESGAAGPTGPIGSRGPS-GPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGA 647
Query: 142 WETSGGHGIFGS---QGGLGGQGQ----GNPGGLGTPWVHGYPGN--SAGSFG----MNP 188
GG G G +G +G G+ G PG +G P G G+ AG+ G P
Sbjct: 648 AGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGP 707
Query: 189 QGAPWGQGGNGGP--PNFGTNTQGAVAQPGYGSVRASNQNEGCTN-PPPSGSGGGSSNSG 245
+G+P G+ G GP PN GA QPG R + +G P+G G + +G
Sbjct: 708 RGSP-GERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAG 766
Query: 246 -GGSGSQSGSSGSGS-NGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSG 301
G +GS G G G ++G + SG S G +G G G RGD G
Sbjct: 767 PNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQG 826
Query: 302 SESSWGS----STGSSSGNHGGSG-GGNGHKPGCEKPGNEARGSGESGIQGFRGQ 351
G +G G SG G PG P G G+ G RG+
Sbjct: 827 PVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGE 881
Score = 68.2 bits (165), Expect = 1e-11
Identities = 117/430 (27%), Positives = 158/430 (36%), Gaps = 82/430 (19%)
Query: 18 SGEAGPL-------QSGEESTGTNIGE-ALGHGLGDALSEGVGKAIGKE-AGGAAGSKVS 68
SG AGP SG N GE + +G A G G+ A G G K
Sbjct: 597 SGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGK-G 655
Query: 69 EALGQGTREAVGT----GVRQVPGF----GAADALGNRVGEAAHA--------LGNTGH- 111
E G R +G G R PG G A A G+R GEA A G+ G
Sbjct: 656 EKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDR-GEAGAAGPAGPAGPRGSPGER 714
Query: 112 -EIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL-- 168
E+G + A A G G GA G +G+ G G +G G P G
Sbjct: 715 GEVGPAGPNGFAGPAGAA--GQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPG 772
Query: 169 --------GTPWVHGYPGNSAGSFGMNPQG--------APWGQGGNGGP-----PNFGTN 207
G P + G+PG + + P G P G+ G GP P T
Sbjct: 773 PAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTG 832
Query: 208 TQGAVAQPGYGSVRASNQNEGCTNPP----PSGSGGGSSNSG-GGSGSQSGSSG-SGSNG 261
GAV PG+ + + G PP P G G G GS + G G +G+ G
Sbjct: 833 EVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVG 892
Query: 262 D-------NNNGSSSGGSSSGSSSGGSSGGSSG--GSSGNSG--------GSRGDSGSES 304
+ G+ + GS + G +G G+ GN G G +G+ G
Sbjct: 893 EPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPG 952
Query: 305 SWGS-STGSSSGNHG--GSGGGNGHKPGCEKPGNEARGSGESGIQGFRG-QGVSSNMREI 360
+ G + G HG G G +G++ G P +G G +G G QG+ + E
Sbjct: 953 NIGPVGAAGAPGPHGPVGPAGKHGNR-GETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEP 1011
Query: 361 SKEGNRLLGG 370
++G R L G
Sbjct: 1012 GEKGPRGLPG 1021
Score = 61.6 bits (148), Expect = 1e-09
Identities = 65/240 (27%), Positives = 86/240 (35%), Gaps = 23/240 (9%)
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQG-------QGNPGGLGTPWVHGYPGNSA--GS 183
+G PG +G G G G QGG G QG QG PG G G PG G
Sbjct: 519 RGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGE 578
Query: 184 FGM----NPQG--APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPP-PSG 236
FG+ P+G P G+ G GP ++G PG + G PSG
Sbjct: 579 FGLPGPAGPRGERGPPGESGAAGPTG-PIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSG 637
Query: 237 SGG--GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG 294
G G + G G + G G+ N G + + G + G G +G
Sbjct: 638 PSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAG 697
Query: 295 --GSRGDSGSESSWG--SSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRG 350
G G +G S G G + N G +PG + GE+G+ G G
Sbjct: 698 AAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTG 757
Score = 60.1 bits (144), Expect = 4e-09
Identities = 78/266 (29%), Positives = 93/266 (34%), Gaps = 29/266 (10%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ----GNPGGLGT---PWVHGYPGNSAGSFGM 186
G PG G G G+ GS+G G G G PG LG P G PG + GS G+
Sbjct: 859 GTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPG-AVGSPGV 917
Query: 187 NPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTN----PPPSGSGGGSS 242
N GAP G +G P N G G QPG+ R N G P P G G +
Sbjct: 918 N--GAPGEAGRDGNPGNDG--PPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAG 973
Query: 243 NSGG-GSGSQSGSSG-SGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG------ 294
G G SG G +G+ G G G G G++G
Sbjct: 974 KHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPG 1033
Query: 295 --GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGH--KPGCEKPGNEARGSGESGIQGFRG 350
G GD G+ S G + G G +G PG P G G G G
Sbjct: 1034 IAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPG 1093
Query: 351 QGVSSNMREISKEGNRLLGGSGDNYR 376
+S G G GD YR
Sbjct: 1094 PPGPPGPPGVS-GGGYDFGYDGDFYR 1118
Score = 55.1 bits (131), Expect = 1e-07
Identities = 56/244 (22%), Positives = 84/244 (34%), Gaps = 29/244 (11%)
Query: 134 GVPGHNGAWETS-GGHGIFGSQGGLGGQG-QGNPGGLGTPWVHGY---------PGNSAG 182
G PG G + G G+ G +G G +G PG G P G+ PG +
Sbjct: 69 GPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGP 128
Query: 183 SFGMNPQGAPWGQGGNGG--------------PPNFGTNTQGAVAQPGYGSVRASNQNEG 228
+ P G P G+ G G P G PG+ +R N +G
Sbjct: 129 AGARGPAGPP-GKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDG 187
Query: 229 CTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGG 288
P + G + G +G+ + G G+ + G + + S G G
Sbjct: 188 LKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAG 247
Query: 289 SSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ 346
G++G G G G + G+ + G G G PG P G +G+
Sbjct: 248 PIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVG-LPGLSGPVGPPGNPGANGLT 306
Query: 347 GFRG 350
G +G
Sbjct: 307 GAKG 310
Score = 52.4 bits (124), Expect = 8e-07
Identities = 67/264 (25%), Positives = 80/264 (30%), Gaps = 41/264 (15%)
Query: 118 EDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYP 177
E+ +R G RG G G G G G G G G P GLG + Y
Sbjct: 27 EETVRKGPAGDRGP----RGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYD 82
Query: 178 GNSAGSFGMNPQG-----APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNP 232
G G G P G P G G GP F QG +PG G P
Sbjct: 83 GKGVG-LGPGPMGLMGPRGPPGAAGAPGPQGF----QGPAGEPGEPGQTGPAGARGPAGP 137
Query: 233 PPSGSGGGSSNSGGGSGSQ-----SGSSG----------SGSNGDNNNGSSSGGSSSGSS 277
P G G G + G+ G G G N G +
Sbjct: 138 PGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGV 197
Query: 278 SGGSSGGSSGGSSGNSG-----------GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGH 326
G G+ G +G G+ G +G+ S GS GS G G
Sbjct: 198 KGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGF 257
Query: 327 KPGCEKPGNEARGSGESGIQGFRG 350
PG P E G +G G G
Sbjct: 258 -PGAPGPKGEIGAVGNAGPAGPAG 280
Score = 47.4 bits (111), Expect = 2e-05
Identities = 78/283 (27%), Positives = 97/283 (34%), Gaps = 18/283 (6%)
Query: 18 SGEAGPLQSGEESTGTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGTR 76
+GE GP SGE T G GL G G+ + G+ V E G
Sbjct: 843 AGEKGP--SGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGI- 899
Query: 77 EAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVP 136
A G R PG + + GEA GN G++ G D + G RG + G
Sbjct: 900 -AGPPGARGPPGAVGSPGVNGAPGEAGRD-GNPGND-GPPGRDG-QPGHKGERG-YPGNI 954
Query: 137 GHNGAWETSGGHGIFGSQGGLGGQGQGNPGG-LGTPWVHGYPGNSAGSFGMNPQGAPWGQ 195
G GA G HG G G G +G+ P G +G G G S +G P +
Sbjct: 955 GPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEK 1014
Query: 196 GGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPP-PSGSGGGSSNSG-----GGSG 249
G G P G N G PG G P P G G S +G G G
Sbjct: 1015 GPRGLPGLKGHN--GLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPG 1072
Query: 250 SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGN 292
+ + G G G G S GG G G+
Sbjct: 1073 TVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSGGGYDFGYDGD 1115
>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
Length = 1257
Score = 77.8 bits (190), Expect = 2e-14
Identities = 51/144 (35%), Positives = 59/144 (40%), Gaps = 4/144 (2%)
Query: 200 GPPNFGT--NTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGS 257
G NFG N QG Q G G N G N SG G GS+ G S S G+ S
Sbjct: 464 GSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCS 523
Query: 258 GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNH 317
G + G S G SG + G + G G+ GG R G S G G G+
Sbjct: 524 GEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSG 583
Query: 318 GG--SGGGNGHKPGCEKPGNEARG 339
GG SGGG G G G+ RG
Sbjct: 584 GGKNSGGGKGSGSGKGSDGDGERG 607
Score = 75.1 bits (183), Expect = 1e-13
Identities = 54/166 (32%), Positives = 69/166 (41%), Gaps = 8/166 (4%)
Query: 202 PNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG---SSNSGGGSGSQSGSSGSG 258
PN G V+ G G+ +G GSGG +N G G+G SG G G
Sbjct: 450 PNNGARLSSEVSGSGSGNFGEEGNPQG--KEDQEGSGGDYMPMNNWGSGNGRGSGG-GQG 506
Query: 259 SNGDNNNGSSSGGSSSGSSSGGSSGG--SSGGSSGNSGGSRGDSGSESSWGSSTGSSSGN 316
SNG ++ SSGG+ GS GG S+G SG + SR G+ GS G G
Sbjct: 507 SNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGG 566
Query: 317 HGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISK 362
GSGGG G G G + G G+ G G + + K
Sbjct: 567 GHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKK 612
Score = 67.0 bits (162), Expect = 3e-11
Identities = 61/185 (32%), Positives = 72/185 (38%), Gaps = 46/185 (24%)
Query: 143 ETSG-GHGIFGSQGG-LGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGG 200
E SG G G FG +G G + Q GG P + GN GS G GQG NG
Sbjct: 459 EVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGG--------GQGSNG- 509
Query: 201 PPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSN 260
QG+ S S GG+ SG G GS+ G GSN
Sbjct: 510 --------QGS----------------------SSHSSGGNQCSGEGQGSR---GGQGSN 536
Query: 261 GDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGS 320
G + G+ G++ G SGG G G GS G G GS G +SG GS
Sbjct: 537 GQGSGGNQCSRDGQGTAGGHGSGG--GQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGS 594
Query: 321 GGGNG 325
G G G
Sbjct: 595 GSGKG 599
Score = 65.9 bits (159), Expect = 7e-11
Identities = 54/172 (31%), Positives = 70/172 (40%), Gaps = 21/172 (12%)
Query: 157 LGGQGQGNPGGLGTPWVHGYPGNSAGSF-GMNPQGAPWGQGGNGGPPNFGTNTQGAVAQP 215
+ G G GN G G P S G + MN G+ G+G GG G+N QG+
Sbjct: 460 VSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQ---GSNGQGS---- 512
Query: 216 GYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSG 275
S +S N+ C+ GG SN G G+Q G G+ G + +G GG G
Sbjct: 513 ---SSHSSGGNQ-CSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSG---GGQRPG 565
Query: 276 SSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK 327
G SGG G G+ G G S G +GS G+ G G K
Sbjct: 566 GGHG--SGGGQGPGDGHGSG----GGKNSGGGKGSGSGKGSDGDGERGKSLK 611
Score = 65.5 bits (158), Expect = 9e-11
Identities = 52/153 (33%), Positives = 61/153 (39%), Gaps = 20/153 (13%)
Query: 237 SGGGSSNSGGGSGSQSGSSGSGSNGD----NNNGSSSGGSSSGSSSGGSSGGSSGGSSGN 292
SG GS N G Q GS GD NN GS +G S G G SS S GN
Sbjct: 461 SGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN 520
Query: 293 --SGGSRGDSGSESSWGSSTGSS------SGNHGGSGGGNGHKPGCEKPGNEARGSGESG 344
SG +G G + S G +G + G GG G G G +PG G G G+
Sbjct: 521 QCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPG----GGHGSGGGQGP 576
Query: 345 IQGF-RGQGVSSNMREISKEGNRLLGGSGDNYR 376
G G G +S + S G G GD R
Sbjct: 577 GDGHGSGGGKNSGGGKGSGSGK---GSDGDGER 606
Score = 60.1 bits (144), Expect = 4e-09
Identities = 55/210 (26%), Positives = 80/210 (38%), Gaps = 41/210 (19%)
Query: 59 AGGAAGSKVSEALGQGTREAVGTGVRQVP--GFGAADALGNRVGEAAHALGNTGHEIGRQ 116
+G +G+ E QG + G+G +P +G+ + G+ G+ ++ G++ H
Sbjct: 461 SGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHS---- 516
Query: 117 AEDVIRHGADAVRGSWQGVPGHNGA--------------WETSGGHGIFGSQGGLGGQGQ 162
G + G QG G G+ T+GGHG G Q GG G
Sbjct: 517 ------SGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGS 570
Query: 163 GNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRA 222
G GG G PG+ GS G G G G G G + + +G +
Sbjct: 571 G--GGQG-------PGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQ 621
Query: 223 SNQNE------GCTNPPPSGSGGGSSNSGG 246
S Q + PPP+G GG SGG
Sbjct: 622 SKQQQMPPPPPPPPPPPPAGGTGGKGKSGG 651
Score = 49.7 bits (117), Expect = 5e-06
Identities = 46/160 (28%), Positives = 61/160 (38%), Gaps = 12/160 (7%)
Query: 233 PPSGSGGGSSNSGGGSGSQSGSSGSGSN--GDNNNGSSSGGSSSGSSSGGSSGGSSGGSS 290
P G+ S SGS SG+ G N G + S G ++ G +G SGG
Sbjct: 446 PAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQ 505
Query: 291 GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPG---CEKPG-NEARGSGESGIQ 346
G++G +G S S +G G+ GG G NG G C + G A G G G Q
Sbjct: 506 GSNG--QGSSSHSSGGNQCSGEGQGSRGGQ-GSNGQGSGGNQCSRDGQGTAGGHGSGGGQ 562
Query: 347 ---GFRGQGVSSNMREISKEGNRLLGGSGDNYRNSETSPG 383
G G G + G G G + + S G
Sbjct: 563 RPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDG 602
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 77.4 bits (189), Expect = 2e-14
Identities = 67/233 (28%), Positives = 85/233 (36%), Gaps = 16/233 (6%)
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL----GTPWVHGYPGNSAGSFGMN 187
+ G+ G G +G G GS G G GQ P GL G P G P + G+ G
Sbjct: 270 FSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPG-PAGARGNDGAT 328
Query: 188 PQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGG 247
P G G GPP F GA + G R S +G P G++ G
Sbjct: 329 GAAGPPGPTGPAGPPGF-PGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGN 387
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG-----GSRGDSGS 302
G+ G+NG + G + SG G G GNSG GS+GD+G+
Sbjct: 388 PGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGA 447
Query: 303 ESSWG----SSTGSSSGNHGGSGG-GNGHKPGCEKPGNEARGSGESGIQGFRG 350
+ G +G G G G G P E G G G G G
Sbjct: 448 KGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADG 500
Score = 73.6 bits (179), Expect = 3e-13
Identities = 93/337 (27%), Positives = 121/337 (35%), Gaps = 47/337 (13%)
Query: 52 GKAIGKEAGGAAGSKVSEALGQGTREAVGT----GVRQVPGFGAADALGNRVGEAAHALG 107
G A + A GA G+ ++ G A G+ G++ +PG A L G+ A G
Sbjct: 692 GPAGPRGANGAPGNDGAKG-DAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDA-G 749
Query: 108 NTGHEIGRQAEDVIRHGADAVRGSWQ-GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPG 166
G + G +D +R + G PG G SG G G++G G +G+ P
Sbjct: 750 PKGAD-GSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPP 808
Query: 167 G----LGTPWVHGYPG--NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSV 220
G G P G PG G G P G G GPP G V PG
Sbjct: 809 GPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPG----PIGNVGAPGAKGA 864
Query: 221 RASNQNEGCTN----------PPPSGSGG-----GSSNSGGGSGSQSGSSGSGSNGDNNN 265
R S G T P PSG+ G G + GG G + + +G G+
Sbjct: 865 RGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGP 924
Query: 266 GSSSGGSSSGSSSGGSSGGSSGGSSGNSG-----------GSRGDSGSESSWGSSTGSSS 314
G + S G + G+ G G G RG+ G G S
Sbjct: 925 PGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPS--GEP 982
Query: 315 GNHGGSG-GGNGHKPGCEKPGNEARGSGESGIQGFRG 350
G G SG G PG P A GESG +G G
Sbjct: 983 GKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPG 1019
Score = 68.6 bits (166), Expect = 1e-11
Identities = 85/307 (27%), Positives = 106/307 (34%), Gaps = 49/307 (15%)
Query: 59 AGGAAGSKVSEALGQGTREAVGT-------GVRQVPGFGAADALGNRVGEAAHALGNTGH 111
A G AG K EA QG G G PGF GEA G G
Sbjct: 606 AVGPAG-KDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEA----GKPGE 660
Query: 112 EIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQ-------GN 164
+ D+ G RG +G PG G G G G+ G G G G
Sbjct: 661 Q--GVPGDLGAPGPSGARGE-RGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGA 717
Query: 165 PGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASN 224
PG G P + G PG G+ G+ P G G+ GP +GA PG VR
Sbjct: 718 PGSQGAPGLQGMPGER-GAAGLP---GPKGDRGDAGP-------KGADGSPGKDGVRGLT 766
Query: 225 QNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGG 284
G PP G G SG + G+ GD G + G
Sbjct: 767 ---GPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQP 823
Query: 285 SSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGS-GES 343
+ G G++G ++GD+G G + + G+ G G ARGS G
Sbjct: 824 GAKGEPGDAG-AKGDAGPPGPAGPAGPPGPIGNVGAPGAKG-----------ARGSAGPP 871
Query: 344 GIQGFRG 350
G GF G
Sbjct: 872 GATGFPG 878
Score = 67.4 bits (163), Expect = 2e-11
Identities = 93/336 (27%), Positives = 119/336 (35%), Gaps = 44/336 (13%)
Query: 61 GAAGSKVSEALGQGTREAVGT-GVRQVPG----FGAADALGNRVGEAAHALGNTGHEIGR 115
GA G+K EA QG R + G GVR PG GAA GN + G G +
Sbjct: 347 GAVGAK-GEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGAD-----GQPGAKGAN 400
Query: 116 QAEDVI-RHGADAVRGSW--QGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL-GTP 171
A + G RG QG G G SG G GS+G G +G+ P G+ G P
Sbjct: 401 GAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPP 460
Query: 172 WVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQP-GYGSVRASNQNEGCT 230
G G P G P G GGP + G VA P G R S G
Sbjct: 461 GPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPK 520
Query: 231 NPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSG-----GSSSGSSSGGSSG-- 283
P G + G G G +G +G G + G +G
Sbjct: 521 GSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVM 580
Query: 284 ------GSSG--GSSGNSG-----------GSRGDSGSESSWGSSTGSSSGNHGGSGGGN 324
G++G G +G G G G++G++ G + + G G
Sbjct: 581 GFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSP 640
Query: 325 GHK--PGCEKPGNEARGSGESGIQGFRGQGVSSNMR 358
G + PG P EA GE G+ G G S R
Sbjct: 641 GFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGAR 676
Score = 66.2 bits (160), Expect = 5e-11
Identities = 87/313 (27%), Positives = 114/313 (36%), Gaps = 49/313 (15%)
Query: 59 AGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAE 118
A G AG++ ++ TG PGF A VG A G G + R +E
Sbjct: 315 APGPAGARGNDGATGAAGPPGPTGPAGPPGFPGA------VG----AKGEAGPQGPRGSE 364
Query: 119 DVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPG 178
G VRG G PG GA +G G G G G G PG G P G+PG
Sbjct: 365 -----GPQGVRGE-PGPPGPAGAAGPAGNPGADGQPGAKGANGA--PGIAGAP---GFPG 413
Query: 179 NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQ-GAVAQPGYGSV------------RASNQ 225
S P G P +G +G P G+ GA +PG V R +
Sbjct: 414 ARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARG 473
Query: 226 NEGCTN--PPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSG 283
G T PP GG S G+ +G G + + GS + G +G
Sbjct: 474 EPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAG 533
Query: 284 --GSSG--GSSGNSG-----GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPG 334
G+ G GS G+ G G G +G + G + G G G K +PG
Sbjct: 534 LPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPG 593
Query: 335 NEARGSGESGIQG 347
+GE G+ G
Sbjct: 594 K----AGERGVPG 602
Score = 64.3 bits (155), Expect = 2e-10
Identities = 65/256 (25%), Positives = 89/256 (34%), Gaps = 22/256 (8%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQG--A 191
G PG GA ++G G G G G G P G P G PG + G P+G
Sbjct: 857 GAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGP--PGPPGPAGKEGGKGPRGETG 914
Query: 192 PWGQGGNGGPP--------NFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSN 243
P G+ G GPP G PG + G P G
Sbjct: 915 PAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPG 974
Query: 244 SGGGSGSQSGSSGSGSNGDNNNGSSSG--------GSSSGSSSGGSSGGSSGGSSGNSGG 295
G SG SG++G+ G G S + G+ G S + G
Sbjct: 975 LPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKG 1034
Query: 296 SRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRG-QGVS 354
RG++G G+ + G G +G + G P A G G +G G QG
Sbjct: 1035 DRGETGPAGPPGAPGAPGAPGPVGPAGKSGDR-GETGPAGPAGPVGPVGARGPAGPQGPR 1093
Query: 355 SNMREISKEGNRLLGG 370
+ E ++G+R + G
Sbjct: 1094 GDKGETGEQGDRGIKG 1109
Score = 63.9 bits (154), Expect = 3e-10
Identities = 66/245 (26%), Positives = 81/245 (33%), Gaps = 40/245 (16%)
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQG----QGNPGGLGTPWVHGYPGNSAGSFGMNP 188
+GVPG GA +G G G+QG G G +G G G+P G PG
Sbjct: 598 RGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPG---------- 647
Query: 189 QGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASN---QNEGCTNPP----PSGSGGGS 241
P G G G P G + PG R G PP P G+ G
Sbjct: 648 ---PAGPPGEAGKPG-EQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAP 703
Query: 242 SNSG--------GGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNS 293
N G G GSQ G G+ G +G S G G
Sbjct: 704 GNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVR 763
Query: 294 G-----GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK--PGCEKPGNEARGSGESGIQ 346
G G G +G+ G S S G+ G G + PG P A G G
Sbjct: 764 GLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQP 823
Query: 347 GFRGQ 351
G +G+
Sbjct: 824 GAKGE 828
Score = 59.3 bits (142), Expect = 6e-09
Identities = 61/226 (26%), Positives = 78/226 (34%), Gaps = 24/226 (10%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAGSFGMNPQGAP 192
G G G G G G QG G G+ G PG +G P + G PG S +G+P
Sbjct: 965 GQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSP 1024
Query: 193 W-----------GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS 241
G+ G GPP GA PG + + G T P G
Sbjct: 1025 GRDGSPGAKGDRGETGPAGPPG----APGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGP 1080
Query: 242 SNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSG 301
+ G +G Q G G+ + G G S G G SG S G +G
Sbjct: 1081 VGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGAS-GPAG 1139
Query: 302 SESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQG 347
GS+ G G NG PG R +G++G G
Sbjct: 1140 PRGPPGSAGAP------GKDGLNGLPGPIGPPGPRGR-TGDAGPVG 1178
Score = 57.0 bits (136), Expect = 3e-08
Identities = 64/235 (27%), Positives = 84/235 (35%), Gaps = 34/235 (14%)
Query: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQG-QGNPGGLGTPWVHGYPGN 179
+ +G D VPG G SG G+ G G G QG QG PG PG
Sbjct: 163 LSYGYDEKSTGGISVPGPMGP---SGPRGLPGPPGAPGPQGFQGPPGE---------PGE 210
Query: 180 SAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGG 239
S M P+G P G NG G +PG R P P G+ G
Sbjct: 211 PGASGPMGPRGPPGPPGKNG--------DDGEAGKPGRPGERGP--------PGPQGARG 254
Query: 240 --GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--G 295
G++ G G + S G+ GD G S +G G G G G
Sbjct: 255 LPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPG 314
Query: 296 SRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRG 350
+ G +G+ + G++ + G G G PG EA G G +G +G
Sbjct: 315 APGPAGARGNDGATGAAGPPGPTGPAGPPGF-PGAVGAKGEAGPQGPRGSEGPQG 368
Score = 53.9 bits (128), Expect = 3e-07
Identities = 61/239 (25%), Positives = 77/239 (32%), Gaps = 25/239 (10%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWV-HGYPGNSAGSFGMNPQGAP 192
G PG +G G G+ G G G G GG P + +GY S G + P
Sbjct: 127 GPPGRDGI---PGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGP 183
Query: 193 WGQGGNGGPPNF--GTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGS 250
G G GPP QG +PG G PP G + G G
Sbjct: 184 SGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGE 243
Query: 251 QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWG- 307
+ G+ G G SG G +G G GS G++G+ G
Sbjct: 244 RGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGP 303
Query: 308 ------------SSTGSSSGNHG--GSGGGNGHKPGCEKPG--NEARGSGESGIQGFRG 350
+ GN G G+ G G PG GE+G QG RG
Sbjct: 304 RGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRG 362
Score = 38.5 bits (88), Expect = 0.011
Identities = 30/76 (39%), Positives = 34/76 (44%), Gaps = 8/76 (10%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ----GNPGGLGTPWVHGYPGNSAGSFGMNPQ 189
G PG G SG G G G G G+ G PG +G P G G+ AG G P
Sbjct: 1124 GSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGD-AGPVG--PP 1180
Query: 190 GAPWGQGGNGGPPNFG 205
G P G G GPP+ G
Sbjct: 1181 GPP-GPPGPPGPPSAG 1195
Score = 35.8 bits (81), Expect = 0.074
Identities = 29/85 (34%), Positives = 32/85 (37%), Gaps = 9/85 (10%)
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGG-LGTPWVHGYPGNSAGSFGMNPQGA 191
+G+ GH G G G GS G G G P G G P G PG G+N
Sbjct: 1105 RGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKD----GLNGLPG 1160
Query: 192 PWGQGGNGGPPNFGTNTQGAVAQPG 216
P G G P T G V PG
Sbjct: 1161 PIGPPG----PRGRTGDAGPVGPPG 1181
>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
Length = 1073
Score = 77.4 bits (189), Expect = 2e-14
Identities = 79/269 (29%), Positives = 100/269 (37%), Gaps = 31/269 (11%)
Query: 124 GADAVRGSW-----QGVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYP 177
GAD + G+ QG PG G G G+ G G G +G+ G PG G P G P
Sbjct: 651 GADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEP 710
Query: 178 GNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNP--PPS 235
G P G G +G P G + GA+ PG + + + G T P P
Sbjct: 711 GLPGPEGARGPPGFKGHTGDSGAPGPRGES--GAMGLPGQEGLPGKDGDTGPTGPQGPQG 768
Query: 236 GSGGGSSNSGGGSGSQSGSSGS----GSNGDNNNGSSSG--GSSSGSSSGGSSG--GSSG 287
G N GS + G SG+ GS G+N + G G G G G G
Sbjct: 769 PRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEG 828
Query: 288 --GSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK--------PGCEKPGN 335
G G G G RGD G + G G G G GH PG P
Sbjct: 829 VPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVG 888
Query: 336 EARGSGESGIQGFRGQGVS-SNMREISKE 363
G+ G G RG+ S +R + +E
Sbjct: 889 PPGPPGQPGFPGLRGESPSMETLRRLIQE 917
Score = 70.5 bits (171), Expect = 3e-12
Identities = 67/245 (27%), Positives = 85/245 (34%), Gaps = 21/245 (8%)
Query: 122 RHGADAVRGSW--QGVPGHNGAWETSGGHGIFGSQGGLGGQGQ----GNPGGLGTPWVHG 175
R G + +G G+PG G G G G+ G +G +G G PG +G P G
Sbjct: 589 REGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPG 648
Query: 176 YPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPS 235
PG + P G G G GPP QG PG +G PP
Sbjct: 649 PPGADGIAGAAGPPGIQ-GSPGKEGPPG----PQGPSGLPGIPGEEGKEGRDGKPGPPGE 703
Query: 236 GSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG- 294
G G G++ G GD+ G S + G G +G +G
Sbjct: 704 PGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGP 763
Query: 295 -------GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK--PGCEKPGNEARGSGESGI 345
G G +GS S G S + GS G NG PG P GE G+
Sbjct: 764 QGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGV 823
Query: 346 QGFRG 350
G G
Sbjct: 824 PGKEG 828
Score = 63.5 bits (153), Expect = 3e-10
Identities = 63/225 (28%), Positives = 81/225 (36%), Gaps = 26/225 (11%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPW 193
G PG G H + G G+ +G+PG G P + G PG P GA
Sbjct: 328 GPPGLPGTTSLFTPHPRMPGEQGPKGE-KGDPGLPGEPGLQGRPGELGPQGPTGPPGAKG 386
Query: 194 GQGGNGGPPNFGTNTQGAVAQPGY-GSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQS 252
+G +G P GA PG G V A G + PP S G + G G +
Sbjct: 387 QEGAHGAP--------GAAGNPGAPGHVGA----PGPSGPPGSVGAPGLRGTPGKDGERG 434
Query: 253 GSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSG-----GSSGNSG--GSRGDSGSESS 305
+G G G + G G G GS G G G++GD G+
Sbjct: 435 EKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGI 494
Query: 306 WGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRG 350
G S G+ G G G PG P + G G+ GF G
Sbjct: 495 PG-----SPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPG 534
Score = 56.2 bits (134), Expect = 5e-08
Identities = 69/260 (26%), Positives = 87/260 (33%), Gaps = 40/260 (15%)
Query: 122 RHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN-- 179
+ G +RGS PG G T G G G G G +G G G P G PG+
Sbjct: 467 KDGEPGLRGS----PGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKG 522
Query: 180 SAGSFGM----NPQGAPWGQGGNG---------------------GPPNFG--TNTQGAV 212
S GS G+ PQG P G+ G GPP +G
Sbjct: 523 SPGSRGLPGFPGPQG-PAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDK 581
Query: 213 AQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGS 272
PG + +G PP G + G G + G GD + G
Sbjct: 582 GVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFM 641
Query: 273 SSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGC 330
+ G G++G G GS G G G S G G +G KPG
Sbjct: 642 GPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDG-KPG- 699
Query: 331 EKPGNEARGSGESGIQGFRG 350
P E +GE G+ G G
Sbjct: 700 --PPGEPGKAGEPGLPGPEG 717
Score = 48.5 bits (114), Expect = 1e-05
Identities = 83/323 (25%), Positives = 104/323 (32%), Gaps = 58/323 (17%)
Query: 82 GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGA 141
G + PG L R GE G TG + E HGA G+ G PGH GA
Sbjct: 353 GEKGDPGLPGEPGLQGRPGELGPQ-GPTGPPGAKGQEGA--HGAPGAAGN-PGAPGHVGA 408
Query: 142 WETSGGHGIFGSQGGLGGQG-------------QGNPGGLG------TPWVHGYPGNSA- 181
SG G G+ G G G +G+PG +G P + G PG
Sbjct: 409 PGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKD 468
Query: 182 ------GSFGM----------NPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQ 225
GS G+ G P G G P G PG S
Sbjct: 469 GEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRG 528
Query: 226 NEGCTNPP-PSGSGGGSSNSGGG----------SGSQSGSSG----SGSNGDNNNGSSSG 270
G P P+G G SS G + G G G GD G
Sbjct: 529 LPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPG 588
Query: 271 GSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKP 328
+ G + G G +G GS+G+ G++ G G G G+ P
Sbjct: 589 REGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGN-P 647
Query: 329 GCEKPGNEARGSGESGIQGFRGQ 351
G A +G GIQG G+
Sbjct: 648 GPPGADGIAGAAGPPGIQGSPGK 670
Score = 45.4 bits (106), Expect = 9e-05
Identities = 81/333 (24%), Positives = 107/333 (32%), Gaps = 72/333 (21%)
Query: 82 GVRQVPGF----GAADALGNRVGEAAHALGNTGHE-IGRQAEDVIRHGADAVRGSWQGVP 136
G R PGF G + A G R GE+ A+G G E + + D G +G +G P
Sbjct: 717 GARGPPGFKGHTGDSGAPGPR-GESG-AMGLPGQEGLPGKDGDTGPTGPQGPQGP-RGPP 773
Query: 137 GHNGAWETSGGHGIFGSQGGLGGQGQ----------------GNPGGLGTPWVHGYPGNS 180
G NG+ + G G G+ G G +G+ G PG G P G PG
Sbjct: 774 GKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPG-K 832
Query: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGY-------GSVRASNQNEGCTNPP 233
G G + G G+ GPP G G PG+ G +N P
Sbjct: 833 PGEPGFKGERGDPGIKGDKGPPG-GKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPG 891
Query: 234 PSGSGGGSSNSGGGSGSQS----------------------------GSSGSGSNGDNNN 265
P G G G ++ S G G
Sbjct: 892 PPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGP 951
Query: 266 GSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWGSSTGSSSGNHG----- 318
G G GG G SG G +G+ G++ G+ G G
Sbjct: 952 PGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIP 1011
Query: 319 GSGGGNGHK----PGCEKPGNEARGSGESGIQG 347
G G G+ PG P E +G G+ G
Sbjct: 1012 GQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPG 1044
Score = 33.9 bits (76), Expect = 0.28
Identities = 29/79 (36%), Positives = 34/79 (43%), Gaps = 10/79 (12%)
Query: 134 GVPGHNGAWETSGG---HGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSA----GSFGM 186
G PG G SG G G++G G G G G +G P + G PG G G+
Sbjct: 968 GRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGI 1027
Query: 187 -NPQG--APWGQGGNGGPP 202
PQG P G G GPP
Sbjct: 1028 PGPQGETGPAGHPGLPGPP 1046
>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
Length = 1626
Score = 77.4 bits (189), Expect = 2e-14
Identities = 79/269 (29%), Positives = 100/269 (37%), Gaps = 31/269 (11%)
Query: 124 GADAVRGSW-----QGVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYP 177
GAD + G+ QG PG G G G+ G G G +G+ G PG G P G P
Sbjct: 1204 GADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEP 1263
Query: 178 GNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNP--PPS 235
G P G G +G P G + GA+ PG + + + G T P P
Sbjct: 1264 GLPGPEGARGPPGFKGHTGDSGAPGPRGES--GAMGLPGQEGLPGKDGDTGPTGPQGPQG 1321
Query: 236 GSGGGSSNSGGGSGSQSGSSGS----GSNGDNNNGSSSG--GSSSGSSSGGSSG--GSSG 287
G N GS + G SG+ GS G+N + G G G G G G
Sbjct: 1322 PRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEG 1381
Query: 288 --GSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK--------PGCEKPGN 335
G G G G RGD G + G G G G GH PG P
Sbjct: 1382 VPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVG 1441
Query: 336 EARGSGESGIQGFRGQGVS-SNMREISKE 363
G+ G G RG+ S +R + +E
Sbjct: 1442 PPGPPGQPGFPGLRGESPSMETLRRLIQE 1470
Score = 60.1 bits (144), Expect = 4e-09
Identities = 85/328 (25%), Positives = 104/328 (31%), Gaps = 68/328 (20%)
Query: 82 GVRQVPGFGAADALGNRVGEAAHALGNTGH----------------EIGRQAEDVIRHGA 125
G R +PGF R G A GN G +I A+DV
Sbjct: 1063 GSRGLPGFPGPQGPAGRDG----APGNPGERGPPGKPGLSSLLSPGDINLLAKDVCN--- 1115
Query: 126 DAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL-GTPWVHGYPGNSAGSF 184
D G G+PG G G G G +G G +G+ P GL G P + G P S G
Sbjct: 1116 DCPPGP-PGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAG-PQGSQGER 1173
Query: 185 G-------------------MNPQGAPWGQGGNG-----GPPNF--------GTNTQGAV 212
G M P G P G +G GPP QG
Sbjct: 1174 GADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPS 1233
Query: 213 AQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGS 272
PG +G PP G G G++ G GD+ G S
Sbjct: 1234 GLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGES 1293
Query: 273 SSGSSSGGSSGGSSGGSSGNSG--------GSRGDSGSESSWGSSTGSSSGNHGGSGGGN 324
+ G G +G +G G G +GS S G S + GS G N
Sbjct: 1294 GAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGEN 1353
Query: 325 GHK--PGCEKPGNEARGSGESGIQGFRG 350
G PG P GE G+ G G
Sbjct: 1354 GSPGLPGFLGPRGPPGEPGEKGVPGKEG 1381
Score = 59.7 bits (143), Expect = 5e-09
Identities = 72/271 (26%), Positives = 92/271 (33%), Gaps = 27/271 (9%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPW 193
G PG G H + G G+ +G+PG G P + G PG P GA
Sbjct: 846 GPPGLPGTTSLFTPHPRMPGEQGPKGE-KGDPGLPGEPGLQGRPGELGPQGPTGPPGAKG 904
Query: 194 GQGGNGGPPNFGT-NTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQS 252
+G +G P G G V PG S G P G + G GS
Sbjct: 905 QEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPG 964
Query: 253 --------------GSSGSGSNGDNNNGSSSG--GSSSGSSSGGSSGGSSGGSSGNSGGS 296
G G G +G+ S G G ++ G GS + G
Sbjct: 965 PVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQ-CV 1023
Query: 297 RGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRG-QGVSS 355
+GD G+ G S G+ G G G PG P + G G+ GF G QG +
Sbjct: 1024 KGDRGAPGIPG-----SPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAG 1078
Query: 356 NMREISKEGNRLLGGSGDNYRNSETSPGMFN 386
G R G G +S SPG N
Sbjct: 1079 RDGAPGNPGER--GPPGKPGLSSLLSPGDIN 1107
Score = 52.4 bits (124), Expect = 8e-07
Identities = 89/361 (24%), Positives = 108/361 (29%), Gaps = 42/361 (11%)
Query: 19 GEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREA 78
G AGP+ G +IG G E IG G G K S L
Sbjct: 487 GVAGPM--GLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRD 544
Query: 79 VGTGVRQVPGFGAADALGNRVGEAAHA-----------LGNTGHEIGRQAEDVIRHGADA 127
G+R PG L VG +G G + G + E R G
Sbjct: 545 GSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQ-GERGEKGTR-GEKG 602
Query: 128 VRG--SWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL--------GTPWVHGYP 177
RG + G PG G G G+ G QG G G P G+ G G P
Sbjct: 603 ERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAP 662
Query: 178 GNSAGSFGMNPQGA--PWGQGGNGGPPNF-----GTNTQGAVAQPGYGSVRASNQNEGCT 230
G P GA P G G GPP G PG ++ G
Sbjct: 663 GPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVP 722
Query: 231 NPPPSGSGGGSSNSGGGSGSQSGSSGSGSNG-DNNNGSSSGGSSSGSSSGGSSGGSSGGS 289
PP G G G G +G G D NG + G G G
Sbjct: 723 GPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPG-- 780
Query: 290 SGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFR 349
G RG+ G + G G+ G PG + GE G+ G +
Sbjct: 781 ---KPGLRGEIGEQGLAGRPGEKGEAGLPGAPG----FPGVRGEKGDQGEKGELGLPGLK 833
Query: 350 G 350
G
Sbjct: 834 G 834
Score = 48.5 bits (114), Expect = 1e-05
Identities = 70/258 (27%), Positives = 82/258 (31%), Gaps = 42/258 (16%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAGSFGM------ 186
G PG G G G G G LG QG G PG G P G PG G G
Sbjct: 687 GPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPG-LPGEIGFPGKPGP 745
Query: 187 -NPQGAPWGQGGNGGPPNFGT----NTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS 241
P G P G NG P GT +G PG +R +G P G
Sbjct: 746 PGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGL 805
Query: 242 SNSGG--GSGSQSGSSGS-------GSNGDNNNGSSSGGSSSGSSSGGSS--------GG 284
+ G G + G G G GD +G + G +S G
Sbjct: 806 PGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPG 865
Query: 285 SSG--GSSGNSG--------GSRGDSGSESSWG-SSTGSSSGNHGGSG-GGNGHKPGCEK 332
G G G+ G G G+ G + G G HG G GN PG
Sbjct: 866 EQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVG 925
Query: 333 PGNEARGSGESGIQGFRG 350
+ G G G RG
Sbjct: 926 APGPSGPPGSVGAPGLRG 943
Score = 45.8 bits (107), Expect = 7e-05
Identities = 53/218 (24%), Positives = 70/218 (32%), Gaps = 30/218 (13%)
Query: 163 GNPGGLGTPWVHGYPGNSAGSFGMNPQGAPW--GQGGNGGPPNFGTNTQGAVAQPGYGSV 220
G G +G G PG + P GAP G+ G+ G FG +G G
Sbjct: 481 GEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGP 540
Query: 221 RASNQNEGCTNPP----------------PSGSGG--GSSNSGGGSGSQSGSSGSGSNGD 262
+ ++G P P G G G G G Q G+ G+
Sbjct: 541 PGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGE 600
Query: 263 NNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWG--SSTGSSSGNHG-- 318
G +G G +G G +GD G G S G G
Sbjct: 601 KGERGLDGFPGKPGDTGQQGRPGPSGVAGPQ-GEKGDVGPAGPPGVPGSVVQQEGLKGEQ 659
Query: 319 GSGGGNGHK-----PGCEKPGNEARGSGESGIQGFRGQ 351
G+ G GH+ PG P G G+QG RG+
Sbjct: 660 GAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGK 697
Score = 45.4 bits (106), Expect = 9e-05
Identities = 81/333 (24%), Positives = 107/333 (32%), Gaps = 72/333 (21%)
Query: 82 GVRQVPGF----GAADALGNRVGEAAHALGNTGHE-IGRQAEDVIRHGADAVRGSWQGVP 136
G R PGF G + A G R GE+ A+G G E + + D G +G +G P
Sbjct: 1270 GARGPPGFKGHTGDSGAPGPR-GESG-AMGLPGQEGLPGKDGDTGPTGPQGPQGP-RGPP 1326
Query: 137 GHNGAWETSGGHGIFGSQGGLGGQGQ----------------GNPGGLGTPWVHGYPGNS 180
G NG+ + G G G+ G G +G+ G PG G P G PG
Sbjct: 1327 GKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPG-K 1385
Query: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGY-------GSVRASNQNEGCTNPP 233
G G + G G+ GPP G G PG+ G +N P
Sbjct: 1386 PGEPGFKGERGDPGIKGDKGPPG-GKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPG 1444
Query: 234 PSGSGGGSSNSGGGSGSQS----------------------------GSSGSGSNGDNNN 265
P G G G ++ S G G
Sbjct: 1445 PPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGP 1504
Query: 266 GSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWGSSTGSSSGNHG----- 318
G G GG G SG G +G+ G++ G+ G G
Sbjct: 1505 PGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIP 1564
Query: 319 GSGGGNGHK----PGCEKPGNEARGSGESGIQG 347
G G G+ PG P E +G G+ G
Sbjct: 1565 GQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPG 1597
Score = 44.7 bits (104), Expect = 2e-04
Identities = 74/269 (27%), Positives = 88/269 (32%), Gaps = 43/269 (15%)
Query: 124 GADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPG--GL-GTPWVHGYPGNS 180
G D RG +G G G+ G G G+ G G G+G G GL G+P + G G
Sbjct: 946 GKDGERGE-KGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTK 1004
Query: 181 A--------------GSFGMNPQGAPW--GQGGNGGPPNFG-TNTQGAVAQPGYGSVRAS 223
A G +GAP G G+ G P G G PG S
Sbjct: 1005 AACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGS 1064
Query: 224 NQNEGCTNPP-PSGSGGGSSNSG-GGSGSQSGSSGSGSNGDNN-------NGSSSGGSSS 274
G P P+G G N G G + G S S GD N N G
Sbjct: 1065 RGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGL 1124
Query: 275 GSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWG----SSTGSSSGNHGGSG-----GG 323
G G G G G +G++G G + S G G G G
Sbjct: 1125 PGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGD 1184
Query: 324 NGHK--PGCEKPGNEARGSGESGIQGFRG 350
GH PG P G GI G G
Sbjct: 1185 QGHPGVPGFMGPPGNPGPPGADGIAGAAG 1213
Score = 33.9 bits (76), Expect = 0.28
Identities = 29/79 (36%), Positives = 34/79 (43%), Gaps = 10/79 (12%)
Query: 134 GVPGHNGAWETSGG---HGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSA----GSFGM 186
G PG G SG G G++G G G G G +G P + G PG G G+
Sbjct: 1521 GRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGI 1580
Query: 187 -NPQG--APWGQGGNGGPP 202
PQG P G G GPP
Sbjct: 1581 PGPQGETGPAGHPGLPGPP 1599
>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
[Homo sapiens]
Length = 2191
Score = 77.4 bits (189), Expect = 2e-14
Identities = 83/342 (24%), Positives = 120/342 (35%), Gaps = 46/342 (13%)
Query: 54 AIGKEAGGAA--GSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGH 111
++G GGA G + + G +++ G PG L ++ G+ A G
Sbjct: 81 SLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG----PPLLSKPGDEDDAPPKMGE 136
Query: 112 EIGRQAEDVIRHGADAVRGSWQ---GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL 168
G + E H G+ Q VPG G F + G G PGG
Sbjct: 137 PAGGRYE----HPGLGALGTQQPPVAVPGGGGG---PAAVPEFNNYYGSAAPASGGPGGR 189
Query: 169 GTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEG 228
P + G + GM + G G + +G Y + + N G
Sbjct: 190 AGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEG------YPNSQC-NHYPG 242
Query: 229 CTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGG 288
+ P G GGG GGGSG G G+G+ G ++ +++ +++GG GG GG
Sbjct: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG 302
Query: 289 SSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGF 348
SS G S G G GGG G A GS G Q F
Sbjct: 303 SSAGYG----------VLSSPRQQGGGMMMGPGGG-----GAASLSKAAAGSAAGGFQRF 347
Query: 349 RGQ-----GVSSNMREISKEGN---RLLGGSGDNYRNSETSP 382
GQ G + + ++ + R GGS Y + P
Sbjct: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPP 389
Score = 48.5 bits (114), Expect = 1e-05
Identities = 79/329 (24%), Positives = 110/329 (33%), Gaps = 31/329 (9%)
Query: 19 GEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTRE 77
G A P G G G HG + G+ + A GA GS + L
Sbjct: 177 GSAAPASGGP---GGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSM--DPLQNSHEG 231
Query: 78 AVGTGVRQVPGF------GAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS 131
+ PG+ G G G + G G G + A A +
Sbjct: 232 YPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAA 291
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVH-GYPGNSAGSFGMNPQG 190
G G G +S G+G+ S GG PGG G + G++AG F +
Sbjct: 292 -AGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGF---QRF 347
Query: 191 APWGQGGNGGPPNFGTN-TQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
A Q +G P T + YG + PPPS ++ +G +G
Sbjct: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407
Query: 250 SQSGSSGSGSNGDNN----NGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS----- 300
Q ++G G D S + ++ S S G+ G + G S GS D
Sbjct: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467
Query: 301 ----GSESSWGSSTGSSSGNHGGSGGGNG 325
G S+ S SS GGS G G
Sbjct: 468 PQLYGMGSNPHSQPQQSSPYPGGSYGPPG 496
>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
[Homo sapiens]
Length = 2231
Score = 77.4 bits (189), Expect = 2e-14
Identities = 83/342 (24%), Positives = 120/342 (35%), Gaps = 46/342 (13%)
Query: 54 AIGKEAGGAA--GSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGH 111
++G GGA G + + G +++ G PG L ++ G+ A G
Sbjct: 81 SLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG----PPLLSKPGDEDDAPPKMGE 136
Query: 112 EIGRQAEDVIRHGADAVRGSWQ---GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL 168
G + E H G+ Q VPG G F + G G PGG
Sbjct: 137 PAGGRYE----HPGLGALGTQQPPVAVPGGGGG---PAAVPEFNNYYGSAAPASGGPGGR 189
Query: 169 GTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEG 228
P + G + GM + G G + +G Y + + N G
Sbjct: 190 AGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEG------YPNSQC-NHYPG 242
Query: 229 CTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGG 288
+ P G GGG GGGSG G G+G+ G ++ +++ +++GG GG GG
Sbjct: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG 302
Query: 289 SSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGF 348
SS G S G G GGG G A GS G Q F
Sbjct: 303 SSAGYG----------VLSSPRQQGGGMMMGPGGG-----GAASLSKAAAGSAAGGFQRF 347
Query: 349 RGQ-----GVSSNMREISKEGN---RLLGGSGDNYRNSETSP 382
GQ G + + ++ + R GGS Y + P
Sbjct: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPP 389
Score = 48.5 bits (114), Expect = 1e-05
Identities = 79/329 (24%), Positives = 110/329 (33%), Gaps = 31/329 (9%)
Query: 19 GEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTRE 77
G A P G G G HG + G+ + A GA GS + L
Sbjct: 177 GSAAPASGGP---GGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSM--DPLQNSHEG 231
Query: 78 AVGTGVRQVPGF------GAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS 131
+ PG+ G G G + G G G + A A +
Sbjct: 232 YPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAA 291
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVH-GYPGNSAGSFGMNPQG 190
G G G +S G+G+ S GG PGG G + G++AG F +
Sbjct: 292 -AGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGF---QRF 347
Query: 191 APWGQGGNGGPPNFGTN-TQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
A Q +G P T + YG + PPPS ++ +G +G
Sbjct: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407
Query: 250 SQSGSSGSGSNGDNN----NGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS----- 300
Q ++G G D S + ++ S S G+ G + G S GS D
Sbjct: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467
Query: 301 ----GSESSWGSSTGSSSGNHGGSGGGNG 325
G S+ S SS GGS G G
Sbjct: 468 PQLYGMGSNPHSQPQQSSPYPGGSYGPPG 496
>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
[Homo sapiens]
Length = 2178
Score = 77.4 bits (189), Expect = 2e-14
Identities = 83/342 (24%), Positives = 120/342 (35%), Gaps = 46/342 (13%)
Query: 54 AIGKEAGGAA--GSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGH 111
++G GGA G + + G +++ G PG L ++ G+ A G
Sbjct: 81 SLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG----PPLLSKPGDEDDAPPKMGE 136
Query: 112 EIGRQAEDVIRHGADAVRGSWQ---GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL 168
G + E H G+ Q VPG G F + G G PGG
Sbjct: 137 PAGGRYE----HPGLGALGTQQPPVAVPGGGGG---PAAVPEFNNYYGSAAPASGGPGGR 189
Query: 169 GTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEG 228
P + G + GM + G G + +G Y + + N G
Sbjct: 190 AGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEG------YPNSQC-NHYPG 242
Query: 229 CTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGG 288
+ P G GGG GGGSG G G+G+ G ++ +++ +++GG GG GG
Sbjct: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG 302
Query: 289 SSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGF 348
SS G S G G GGG G A GS G Q F
Sbjct: 303 SSAGYG----------VLSSPRQQGGGMMMGPGGG-----GAASLSKAAAGSAAGGFQRF 347
Query: 349 RGQ-----GVSSNMREISKEGN---RLLGGSGDNYRNSETSP 382
GQ G + + ++ + R GGS Y + P
Sbjct: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPP 389
Score = 48.5 bits (114), Expect = 1e-05
Identities = 79/329 (24%), Positives = 110/329 (33%), Gaps = 31/329 (9%)
Query: 19 GEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTRE 77
G A P G G G HG + G+ + A GA GS + L
Sbjct: 177 GSAAPASGGP---GGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSM--DPLQNSHEG 231
Query: 78 AVGTGVRQVPGF------GAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS 131
+ PG+ G G G + G G G + A A +
Sbjct: 232 YPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAA 291
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVH-GYPGNSAGSFGMNPQG 190
G G G +S G+G+ S GG PGG G + G++AG F +
Sbjct: 292 -AGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGF---QRF 347
Query: 191 APWGQGGNGGPPNFGTN-TQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
A Q +G P T + YG + PPPS ++ +G +G
Sbjct: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407
Query: 250 SQSGSSGSGSNGDNN----NGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS----- 300
Q ++G G D S + ++ S S G+ G + G S GS D
Sbjct: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467
Query: 301 ----GSESSWGSSTGSSSGNHGGSGGGNG 325
G S+ S SS GGS G G
Sbjct: 468 PQLYGMGSNPHSQPQQSSPYPGGSYGPPG 496
>gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b
[Homo sapiens]
Length = 372
Score = 75.5 bits (184), Expect = 8e-14
Identities = 64/181 (35%), Positives = 83/181 (45%), Gaps = 16/181 (8%)
Query: 137 GHNGAWETSGGHGI-FGSQG--GLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPW 193
G +G+ GG G FG G GG G G G+ GY G+ G G G
Sbjct: 195 GRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDG--- 251
Query: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG 253
G GG G + G+ G+ Q GYG+ + G + +G GGG GGGSGS G
Sbjct: 252 GYGGGGPGYSGGSRGYGSGGQ-GYGNQGSGYGGSGSYDSYNNGGGGGF---GGGSGSNFG 307
Query: 254 SSGSGSN-GDNNNGSSSGGSSSGSSSGGSSGGSSGG-----SSGNSGGSRGDSGSESSWG 307
GS ++ G+ NN SS+ G G + GG S G GG + + G G S S SS+G
Sbjct: 308 GGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYG 367
Query: 308 S 308
S
Sbjct: 368 S 368
Score = 71.6 bits (174), Expect = 1e-12
Identities = 67/201 (33%), Positives = 77/201 (38%), Gaps = 36/201 (17%)
Query: 154 QGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVA 213
+ G G G G GG G G GN +G G G G GG GG G G
Sbjct: 196 RSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGF---GGSRGGGGYGGS---GDGYNGFGN 249
Query: 214 QPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSS 273
GYG GGG SGG G GSG G N GS GGS
Sbjct: 250 DGGYG-------------------GGGPGYSGGSRGY-----GSGGQGYGNQGSGYGGSG 285
Query: 274 SGSSSGGSSGGSSGGSSGNS---GGSRGDSGSESSWGSSTG-SSSGNHGG--SGGGNGHK 327
S S GG GG SG++ GGS D G+ ++ S+ G GN GG SG G
Sbjct: 286 SYDSYNNGGGGGFGGGSGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGG 345
Query: 328 PGCEKPGNEARGSGESGIQGF 348
KP N+ G S +
Sbjct: 346 QYFAKPRNQGGYGGSSSSSSY 366
Score = 65.5 bits (158), Expect = 9e-11
Identities = 46/147 (31%), Positives = 58/147 (39%), Gaps = 11/147 (7%)
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWG 307
S SQ G SGSG+ G G G + G S G GGS G GG G + +G
Sbjct: 190 SSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGG-GGYGGSGDGYNGFG 248
Query: 308 SSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRL 367
+ G G G SGG G+ G + GN+ G G SG G G
Sbjct: 249 NDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNG----------GGGGF 298
Query: 368 LGGSGDNYRNSETSPGMFNFDTFWKNF 394
GGSG N+ + N++ NF
Sbjct: 299 GGGSGSNFGGGGSYNDFGNYNNQSSNF 325
Score = 62.4 bits (150), Expect = 7e-10
Identities = 44/146 (30%), Positives = 57/146 (39%), Gaps = 6/146 (4%)
Query: 240 GSSNSGGGSGSQSGSSGSGSNGDNNNGSSS-GGSSSGSSSGGSSGGSS--GGSSGNSGGS 296
GS N GGG G G + + G N +G GGS G GGS G + G G GG
Sbjct: 198 GSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGGYGGGG 257
Query: 297 RGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSN 356
G SG +GS G GN G GG+G G G G F G G ++
Sbjct: 258 PGYSGGSRGYGSG-GQGYGNQGSGYGGSGSYDSYNNGGGGGFGGGSG--SNFGGGGSYND 314
Query: 357 MREISKEGNRLLGGSGDNYRNSETSP 382
+ + + G N+ + P
Sbjct: 315 FGNYNNQSSNFGPMKGGNFGGRSSGP 340
Score = 59.3 bits (142), Expect = 6e-09
Identities = 45/151 (29%), Positives = 56/151 (37%), Gaps = 10/151 (6%)
Query: 235 SGSGGGSSNSGGGSGSQSGS------SGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGG 288
SGSG GGG G SG G G + G GGS G + G+ GG GG
Sbjct: 197 SGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGGYGGG 256
Query: 289 SSGNSGGSRGDSGSESSWGS--STGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ 346
G SGGSRG +G+ S SG++ G G G N G +
Sbjct: 257 GPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGFGGGSGSNFGGGGSYNDFG 316
Query: 347 GFRGQGVSSNMREISKEGNRLLG--GSGDNY 375
+ Q + + G R G G G Y
Sbjct: 317 NYNNQSSNFGPMKGGNFGGRSSGPYGGGGQY 347
Score = 44.3 bits (103), Expect = 2e-04
Identities = 41/128 (32%), Positives = 50/128 (39%), Gaps = 16/128 (12%)
Query: 260 NGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS--GSESSWGSSTGSSSGNH 317
NG N + +S+ S G SG SGN GG RG G+++ S G
Sbjct: 171 NGHNCEVRKALSKQEMASASSSQRGRSG--SGNFGGGRGGGFGGNDNFGRGGNFSGRGGF 228
Query: 318 GGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRL------LGGS 371
GGS GG G+ G+ G G G G G G S R G GGS
Sbjct: 229 GGSRGGGGYGGS----GDGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGS 284
Query: 372 G--DNYRN 377
G D+Y N
Sbjct: 285 GSYDSYNN 292
>gi|89276766 trophinin isoform 5 [Homo sapiens]
Length = 1431
Score = 75.5 bits (184), Expect = 8e-14
Identities = 111/412 (26%), Positives = 158/412 (38%), Gaps = 69/412 (16%)
Query: 27 GEESTGTNIGEALGHG--LGDAL--SEGVGKAIGKEA------------GGAAGSKVSEA 70
G STG G AL G L S G G A+ A GG+ G+ VS
Sbjct: 961 GSPSTGAGFGGALNTSASFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFGGSPGTSVSFG 1020
Query: 71 LGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAE-------DVIRH 123
T G V FG + G + G + A
Sbjct: 1021 SALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGFGGALNTNASFGCAVSTSASFS 1080
Query: 124 GADAVRGSWQGVP----GHNGAWETSGGHG-IFGSQGGLGGQGQGNPGGLGTPWVHGYPG 178
GA + + G P G GA+ TS G G + GG + G P G
Sbjct: 1081 GAVSTSACFSGAPITNPGFGGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPSTSVSFG 1140
Query: 179 NSAGS---FGMNPQGAP-WGQGGN-----GGPPNFGTNTQGAVAQPGY--GSVRASNQNE 227
+ G+ FG P + +G N GGPP+ GA + P + G ++ +
Sbjct: 1141 GAHGTSLCFGGAPSTSLCFGSASNTNLCFGGPPSTSACFSGATS-PSFCDGPSTSTGFSF 1199
Query: 228 GCTNPPPSGSGGGSSNS---GGGSGSQSGSSG---SGSNGDNNNGSSSG-GSSSGSSSG- 279
G +G GGG + S GGG G+ +G SG + S D G+S+G G G+S+G
Sbjct: 1200 GNGLSTNAGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGGPGTSTGF 1259
Query: 280 ----GSSGGSSGGSSGNSG---------GSRGDSGSESSWGSSTGSSSGNHGG--SGGGN 324
G+S G SGG ++G G G G+ +S+GS+ G+S+G GG + G
Sbjct: 1260 GGGLGTSAGFSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLGTSAGFSGGLSTSDGF 1319
Query: 325 GHKPGCEKPGNEAR----GSGESGIQGFRGQGVSSNMREISKEGNRLLGGSG 372
G +P + GSG + GF G+ S S + ++G SG
Sbjct: 1320 GSRPNASFDRGLSTIIGFGSGSNTSTGFTGE--PSTSTGFSSGPSSIVGFSG 1369
Score = 72.0 bits (175), Expect = 9e-13
Identities = 81/231 (35%), Positives = 92/231 (39%), Gaps = 29/231 (12%)
Query: 137 GHNGAWETSGGHGI-FGSQGGLGG---QGQGNPGGLGTP-WVHGYPGNSAGSFGMNPQGA 191
G G TS G G G+ G G G GGLGT G PG S G FG +
Sbjct: 1208 GFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGGPGTSTG-FGGGLGTS 1266
Query: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQ 251
GG G FG G V G+G +N + G T +G GG S S G GS+
Sbjct: 1267 AGFSGGLGTSAGFGG---GLVTSDGFGGGLGTNASFGSTLGTSAGFSGGLSTS-DGFGSR 1322
Query: 252 SGSS-----------GSGSN---GDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSR 297
+S GSGSN G S+S G SSG S S G SGG S G
Sbjct: 1323 PNASFDRGLSTIIGFGSGSNTSTGFTGEPSTSTGFSSGPS---SIVGFSGGPSTGVGFCS 1379
Query: 298 GDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGF 348
G S S S G STG+ G GG G G G G+ G GF
Sbjct: 1380 GPSTSGFSGGPSTGAGFG--GGPNTGAGFGGGPSTSAGFGSGAASLGACGF 1428
Score = 63.5 bits (153), Expect = 3e-10
Identities = 96/317 (30%), Positives = 115/317 (36%), Gaps = 48/317 (15%)
Query: 13 ALCLGSGEAGPLQ-SGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEAL 71
+LC GS L G ST A D S G + G
Sbjct: 1156 SLCFGSASNTNLCFGGPPSTSACFSGATSPSFCDGPSTSTGFSFGN-------------- 1201
Query: 72 GQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS 131
G T G G+ GFG LG G + ++G + G G A G
Sbjct: 1202 GLSTNAGFGGGLNTSAGFGGG--LGTSAGFSGGLSTSSGFDGGL--------GTSAGFGG 1251
Query: 132 WQGVP-GHNGAWETSGGH-GIFGSQGGLGG---QGQGNPGGLGTPWVHGYP-GNSAGSFG 185
G G G TS G G G+ G GG G GGLGT G G SAG
Sbjct: 1252 GPGTSTGFGGGLGTSAGFSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLGTSAGF-- 1309
Query: 186 MNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSG 245
G G G PN + +G G+GS SN + G T P + +G S
Sbjct: 1310 ---SGGLSTSDGFGSRPNASFD-RGLSTIIGFGS--GSNTSTGFTGEPSTSTGFSS---- 1359
Query: 246 GGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESS 305
G S G SG S G G SG S+SG S GG S G+ G N+G G S S+
Sbjct: 1360 -GPSSIVGFSGGPSTGV---GFCSGPSTSGFS-GGPSTGAGFGGGPNTGAGFGGGPSTSA 1414
Query: 306 WGSSTGSSSGNHGGSGG 322
S +S G G S G
Sbjct: 1415 GFGSGAASLGACGFSYG 1431
Score = 60.5 bits (145), Expect = 3e-09
Identities = 90/335 (26%), Positives = 127/335 (37%), Gaps = 27/335 (8%)
Query: 13 ALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEA--GGAAGSKVSEA 70
A +G G L + + GT ++G G + S G A G GGA + +
Sbjct: 1102 AFSTSAGFGGALSTAADFGGTP-SNSIGFGAAPSTSVSFGGAHGTSLCFGGAPSTSLCFG 1160
Query: 71 LGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRG 130
T G F A + G + + G+ + A A G
Sbjct: 1161 SASNTNLCFGGPPSTSACFSGATSPSFCDGPSTSTGFSFGNGLSTNAGFGGGLNTSAGFG 1220
Query: 131 SWQGVP-GHNGAWETSGGH-GIFGSQGGLGG---QGQGNPGGLGTP-WVHGYPGNSAGSF 184
G G +G TS G G G+ G GG G GGLGT G G SAG
Sbjct: 1221 GGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGGPGTSTGFGGGLGTSAGFSGGLGTSAGFG 1280
Query: 185 GMNPQGAPWGQGGNGGPPNFGTN-------TQGAVAQPGYGSVRASNQNEGCTNPPPSGS 237
G +G GG G +FG+ + G G+GS ++ + G + G
Sbjct: 1281 GGLVTSDGFG-GGLGTNASFGSTLGTSAGFSGGLSTSDGFGSRPNASFDRGLSTI--IGF 1337
Query: 238 GGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSG-------SSSGGSSGGSSGGSS 290
G GS+ S G +G S S+G S+G ++ SGG S+G S+SG S G S+G
Sbjct: 1338 GSGSNTSTGFTGEPSTSTGF-SSGPSSIVGFSGGPSTGVGFCSGPSTSGFSGGPSTGAGF 1396
Query: 291 GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNG 325
G + G S + GS + + G G G
Sbjct: 1397 GGGPNTGAGFGGGPSTSAGFGSGAASLGACGFSYG 1431
Score = 40.0 bits (92), Expect = 0.004
Identities = 37/139 (26%), Positives = 63/139 (45%), Gaps = 7/139 (5%)
Query: 190 GAPWGQGGNGGPPNFGTNTQGA-VAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGS 248
G+P G GG + G+ G+G +++ + G ++ + GG S S
Sbjct: 901 GSPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSICFD 960
Query: 249 GSQSGSSGSGSNGDNNNGSSSGG---SSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESS 305
GS S +G+G G N +S G +S+G S+ GG+ S G G+ S
Sbjct: 961 GSPS--TGAGFGGALNTSASFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFGGSPGTSVS 1018
Query: 306 WGSSTGSSSGNHGGSGGGN 324
+GS+ +++G +GG+ N
Sbjct: 1019 FGSALNTNAG-YGGAVSTN 1036
Score = 39.7 bits (91), Expect = 0.005
Identities = 44/143 (30%), Positives = 58/143 (40%), Gaps = 25/143 (17%)
Query: 199 GGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSG 258
GG P + G V+ G + S G + SG GG S + G SG S S+ G
Sbjct: 814 GGMPCTSASFSGGVSSSFSGPLSTSATFSGGAS---SGFGGTLSTTAGFSGVLSTSTSFG 870
Query: 259 SNGDNNNGSSS------------------GGSSSGSSSGGSSGGSS---GGSSGNSGGSR 297
S + SS GGS S S S G + +S GGS S G
Sbjct: 871 SAPTTSTVFSSALSTSTGFGGILSTSVCFGGSPSSSGSFGGTLSTSICFGGSPCTSTGFG 930
Query: 298 GDSGSESSWGSSTGSSSGNHGGS 320
G + S+G S+ S+S N GG+
Sbjct: 931 GTLSTSVSFGGSS-STSANFGGT 952
Score = 39.7 bits (91), Expect = 0.005
Identities = 40/125 (32%), Positives = 60/125 (48%), Gaps = 8/125 (6%)
Query: 199 GGPPNFGTNTQGAVA-QPGYGSVRASNQNEGCTNPPPSGSGGGS-SNSGGGSGSQSGSSG 256
G P T A++ G+G + +++ G +P SGS GG+ S S GS S+G
Sbjct: 870 GSAPTTSTVFSSALSTSTGFGGILSTSVCFG-GSPSSSGSFGGTLSTSICFGGSPCTSTG 928
Query: 257 SGSNGDNNNGSSSGGSSSGSSSGGSSGGSS---GGSSGNSGGSRGDSGSESSWGSSTGSS 313
G G + S GGSSS S++ G + +S GS G G + +S+GS +S
Sbjct: 929 FG--GTLSTSVSFGGSSSTSANFGGTLSTSICFDGSPSTGAGFGGALNTSASFGSVLNTS 986
Query: 314 SGNHG 318
+G G
Sbjct: 987 TGFGG 991
Score = 35.0 bits (79), Expect = 0.13
Identities = 33/96 (34%), Positives = 43/96 (44%), Gaps = 5/96 (5%)
Query: 231 NPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGS-SSGGSSSGSSSGGSSGGSSGGS 289
N PS SGG GG G G + S S +N S S GG+ S SSS S+ S G
Sbjct: 742 NGAPSSSGG----FSGGPGITFGVAPSTSASFSNTASISFGGTLSTSSSFSSAASISFGC 797
Query: 290 SGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNG 325
+ ++ S S S G S+S + G S +G
Sbjct: 798 AHSTSTSFSSEASISFGGMPCTSASFSGGVSSSFSG 833
Score = 30.8 bits (68), Expect = 2.4
Identities = 40/138 (28%), Positives = 55/138 (39%), Gaps = 16/138 (11%)
Query: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
GAP GG G P T G ++ + G T S +S S G +
Sbjct: 743 GAPSSSGGFSGGPGI---TFGVAPSTSASFSNTASISFGGTLSTSSSFSSAASISFGCAH 799
Query: 250 SQSGSSGS------GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGG----SRGD 299
S S S S G + S G SSS S +S SGG+S GG + G
Sbjct: 800 STSTSFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFGGTLSTTAGF 859
Query: 300 SG---SESSWGSSTGSSS 314
SG + +S+GS+ +S+
Sbjct: 860 SGVLSTSTSFGSAPTTST 877
Score = 28.9 bits (63), Expect = 9.0
Identities = 21/69 (30%), Positives = 37/69 (53%), Gaps = 2/69 (2%)
Query: 254 SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGS--SGGSSGNSGGSRGDSGSESSWGSSTG 311
S G+ + ++G+S + + SSSGG SGG + G + ++ S ++ S S G+ +
Sbjct: 724 SRGASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLST 783
Query: 312 SSSGNHGGS 320
SSS + S
Sbjct: 784 SSSFSSAAS 792
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 75.1 bits (183), Expect = 1e-13
Identities = 80/267 (29%), Positives = 94/267 (35%), Gaps = 41/267 (15%)
Query: 123 HGADAVRGS--------------WQGVPGHNGAWETSGGHGIFGSQGGLGGQG-QGNPGG 167
HG D +GS QG+PG G T G G G G G +G GN G
Sbjct: 737 HGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGA 796
Query: 168 LGTPWVHGYPGNSAGSFGMNPQGAPWG----QGGNGGPPNFGTN----------TQGAVA 213
G P G PG AG G + P G G G P + G N QG
Sbjct: 797 RGLPGPLGPPG-PAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDG 855
Query: 214 QPGY-GSVRASNQNEGCTNPPPSGSGG--GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSG 270
QPG G Q +P P G G G G G + G G G S+G
Sbjct: 856 QPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAG 915
Query: 271 GSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSGG----GN 324
+G G G G G RGD GS G +G GG G G
Sbjct: 916 RVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDR--GPAGPPGGPGDKGDPGE 973
Query: 325 GHKPGCEKPGNEARGSGESGIQGFRGQ 351
+PG + P A +G+ GI G GQ
Sbjct: 974 DGQPGPDGPPGPAGTTGQRGIVGMPGQ 1000
Score = 70.9 bits (172), Expect = 2e-12
Identities = 76/279 (27%), Positives = 103/279 (36%), Gaps = 34/279 (12%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAGSFGMNPQG-- 190
G PG G G G G+ G LG +G+ GNPG G P + G PG + G P G
Sbjct: 684 GPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPK 743
Query: 191 ---APWGQGGNGGPPNF----------GT----NTQGAVAQPGYGSVRASNQNEGCTNPP 233
P G G+ GPP GT +G + + G ++ G P
Sbjct: 744 GSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPL 803
Query: 234 PSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNS 293
G + G G + GS G+ + +G + + +G G G
Sbjct: 804 GPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEP 863
Query: 294 G--GSRGDSGSESSWGSSTGSSSGNHGGSG-----GGNGHK--PGCEKPGNEARGSGESG 344
G G +GD+GS G S G HG +G GG G + PG A G G
Sbjct: 864 GEPGQKGDAGSPGPQG--LAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPG 921
Query: 345 IQGFRGQGVSSNMREISKEG-NRLLGGSGDNYRNSETSP 382
G G + + E KEG L G G + R + P
Sbjct: 922 PAG--APGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGP 958
Score = 69.7 bits (169), Expect = 5e-12
Identities = 69/255 (27%), Positives = 90/255 (35%), Gaps = 26/255 (10%)
Query: 123 HGADAVRG-----SWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGY 176
HG + V G QG PG G ++G G G G G G G PG G P + G
Sbjct: 887 HGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGD 946
Query: 177 PGNSAGSFGMNPQGAPWGQGGNGGP-------PNFGTNTQGAVAQPGYGSVRASNQNEGC 229
PG+ P G P G G G P P+ G Q G + G
Sbjct: 947 PGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGM 1006
Query: 230 TN-PPPSGSGG--GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSS 286
P P+G+ G G + + G G GSNG G + + + G
Sbjct: 1007 PGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGE 1066
Query: 287 GGSSGNSG-----GSRGDSGSESSWGSSTGSSSGNHGGSGG-----GNGHKPGCEKPGNE 336
G G+ G GS+G G+ G+ + GS G G K G P
Sbjct: 1067 RGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGP 1126
Query: 337 ARGSGESGIQGFRGQ 351
G+ G +G RGQ
Sbjct: 1127 RGDKGDHGDRGDRGQ 1141
Score = 67.0 bits (162), Expect = 3e-11
Identities = 91/337 (27%), Positives = 114/337 (33%), Gaps = 56/337 (16%)
Query: 61 GAAGSKVSEALGQGTREAVGT-GVRQVPG----FGAADALGNRVGEAAHAL--------- 106
GA GSK EA G A+G G R +PG G A G R AH +
Sbjct: 315 GAPGSK-GEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQR---GAHGMPGKPGPMGP 370
Query: 107 ----------GNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGG 156
GN G + +A G + +G +G G G + G G G+ G
Sbjct: 371 LGIPGSSGFPGNPGMK--GEAGPTGARGPEGPQGQ-RGETGPPGPVGSPGLPGAIGTDGT 427
Query: 157 LGGQGQ-GNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNT------- 208
G +G G+PG G P G PG+ PQG GQ G+ G P F
Sbjct: 428 PGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIR-GQPGDPGVPGFKGEAGPKGEPG 486
Query: 209 ----QGAVAQPGYGSVRASNQNEGCTNPP-PSGSGGGSSNSG--GGSGSQSGSSGSGSNG 261
QG + PG R + G PP P G G N G G G G G
Sbjct: 487 PHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERG 546
Query: 262 DNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--------GSRGDSGSESSWGSSTGSS 313
+ G G + G +GN G G G G + G
Sbjct: 547 PVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIG 606
Query: 314 SGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRG 350
GS G G K PG +G +G+ G RG
Sbjct: 607 IRGQPGSMGLPGPKGSSGDPGKPGE-AGNAGVPGQRG 642
Score = 65.9 bits (159), Expect = 7e-11
Identities = 78/262 (29%), Positives = 96/262 (36%), Gaps = 41/262 (15%)
Query: 124 GADAVRGSW--QGVPGHNGAWETSGGHGIFGSQGGLGGQGQ-------GNPGGLGTPWV- 173
G +RG GVPG G G G G QG +G G+ G+PG +G P
Sbjct: 459 GPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPV 518
Query: 174 --HGYPGNSA--GSFGM-NPQGAPWGQG--GNGGPPNFGTNTQGAVAQPGYGSVRASNQN 226
G PGN GS G+ P+GA +G G+ GP G +PG R N
Sbjct: 519 GERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKG-SQGDPGRPGEPGLPGARGLTGN 577
Query: 227 EGCTNPP----PSGSGGGSSNSGG----GSGSQSGSSG----SGSNGDNNNGSSSGGSSS 274
G P P G+ G G G Q GS G GS+GD +G +
Sbjct: 578 PGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGV 637
Query: 275 GSSSGGSSGGSSGGSSGNSG-----GSRGDSGSESSWGSSTGSSSGNHGGSG-GGNGHKP 328
G G SG G G RG+ G G G G G G G KP
Sbjct: 638 PGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTG-----FQGLPGPPGPPGEGGKP 692
Query: 329 GCEKPGNEARGSGESGIQGFRG 350
G + + G G +G RG
Sbjct: 693 GDQGVPGDPGAVGPLGPRGERG 714
Score = 60.1 bits (144), Expect = 4e-09
Identities = 81/285 (28%), Positives = 101/285 (35%), Gaps = 30/285 (10%)
Query: 85 QVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWET 144
Q+ G LG++VG ++G G G ++G QG G G
Sbjct: 194 QMAGLDEKSGLGSQVGLMPGSVGPVGPR-----------GPQGLQGQ-QGGAGPTGPPGE 241
Query: 145 SGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNS--AGSFGMNP-QGAPWGQGGNGG 200
G G G G G +G G PG G P +G PG AGS G GAP G G
Sbjct: 242 PGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGH 301
Query: 201 PPNFGTN-TQGAVAQPGYGSVRASNQNEGCTNP-PPSGSGGGSSNSGG-GSGSQSGSSGS 257
+ G +G V PG G P P G G G G+ Q G+ G
Sbjct: 302 RGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGM 361
Query: 258 -GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWGS------ 308
G G G S + G G+ G G G RG++G GS
Sbjct: 362 PGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGA 421
Query: 309 -STGSSSGNHGGSGG-GNGHKPGCEKPGNEARGSGESGIQGFRGQ 351
T + G G +G G PG P G +G QG RGQ
Sbjct: 422 IGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQ 466
Score = 57.8 bits (138), Expect = 2e-08
Identities = 67/247 (27%), Positives = 87/247 (35%), Gaps = 34/247 (13%)
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQG-------QGNPGGLGTPWVHGYPGNSA--GS 183
+G PG +G SG G G G G QG QG PG G P G PG+ G
Sbjct: 641 RGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGD 700
Query: 184 FGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT-NPPPSGSGG--- 239
G P G+ GN G G PG + + +G +P PSG+ G
Sbjct: 701 PGAVGPLGPRGERGNPGE----RGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTG 756
Query: 240 -----------GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGG 288
G + + G G + G G+ G N + G G + G
Sbjct: 757 PPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKG 816
Query: 289 SSGNSG-----GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGES 343
G G GSRG+ GS G + G G G K +PG + +G
Sbjct: 817 EPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKG-DAGSP 875
Query: 344 GIQGFRG 350
G QG G
Sbjct: 876 GPQGLAG 882
Score = 57.0 bits (136), Expect = 3e-08
Identities = 63/234 (26%), Positives = 79/234 (33%), Gaps = 28/234 (11%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNS------------ 180
G PG G G G+ G +G G G+ G G G P G PG
Sbjct: 600 GPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPP 659
Query: 181 --AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG 238
AG G P G G GPP G +PG V G P
Sbjct: 660 GLAGERGEQGPPGPTGFQGLPGPP----GPPGEGGKPGDQGVPGDPGAVGPLGPRGERGN 715
Query: 239 GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GS 296
G G +G +G +G + S G S + +G G G +G G
Sbjct: 716 PGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGP 775
Query: 297 RGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRG 350
+GD G G+ ++GN G G PG P A +GE G G RG
Sbjct: 776 KGDRGGIGEKGAE--GTAGNDGARG-----LPGPLGPPGPAGPTGEKGEPGPRG 822
Score = 56.2 bits (134), Expect = 5e-08
Identities = 77/281 (27%), Positives = 97/281 (34%), Gaps = 24/281 (8%)
Query: 107 GNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQG-QGNP 165
GNT GR+ + +G VP G G G GSQG G +G +G P
Sbjct: 103 GNTNFGRGRKGQ----------KGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRP 152
Query: 166 GGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQ 225
G G + G PG P G P G +G F G + G GS
Sbjct: 153 GPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGL-- 210
Query: 226 NEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGS 285
P S G G G Q G+ +G G+ + G S G
Sbjct: 211 ------MPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPG 264
Query: 286 SGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNE--ARGS-GE 342
G G + G+ G+ G S G+ + G G GHK G E P E A GS GE
Sbjct: 265 EDGEPGRN-GNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHK-GLEGPKGEVGAPGSKGE 322
Query: 343 SGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRNSETSPG 383
+G G G R + E RL R + PG
Sbjct: 323 AGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPG 363
Score = 52.8 bits (125), Expect = 6e-07
Identities = 63/224 (28%), Positives = 75/224 (33%), Gaps = 27/224 (12%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGN--SAGSFGMNPQG 190
G PG G +G G G G G G G PG G G PG + G G
Sbjct: 1014 GTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDP 1073
Query: 191 APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGS 250
P G G+ G P T G V PG R + G PP G + G G
Sbjct: 1074 GPAGLPGSQGAPG----TPGPVGAPGDAGQRGDPGSRGPIGPP------GRAGKRGLPGP 1123
Query: 251 QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWGS 308
Q G +GD + G G G G++G G G G G
Sbjct: 1124 QGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGP 1183
Query: 309 STGSSSGNHGGSGGGNGHKPGCEKPGNEARGS-GESGIQGFRGQ 351
S G G G PG RGS GE+G +G G+
Sbjct: 1184 S---------GKEGNPGPLGPIGPPG--VRGSVGEAGPEGPPGE 1216
Score = 49.3 bits (116), Expect = 6e-06
Identities = 83/321 (25%), Positives = 108/321 (33%), Gaps = 23/321 (7%)
Query: 19 GEAGPL-QSGEESTGTNIGEALGHG-LGDALSEGVGKAIGKEAG----GAAG--SKVSEA 70
G AGPL + G+E G+ HG +GD G G + G G A
Sbjct: 927 GPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPA 986
Query: 71 LGQGTREAVGT----GVRQVPGFGAADALGNRVGEAAHALGNTGHE--IGRQAED--VIR 122
G R VG G R +PG +VG A G+ G +G + V
Sbjct: 987 GTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTG-ATGDKGPPGPVGPPGSNGPVGE 1045
Query: 123 HGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSA 181
G + G+ G PG +GA G G G G G QG G PG +G P G G+
Sbjct: 1046 PGPEGPAGN-DGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPG 1104
Query: 182 GSFGMNPQGAPWGQGGNGGP--PNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGG 239
+ P G G+ G GP P G G R +G PP
Sbjct: 1105 SRGPIGPPGRA-GKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQ 1163
Query: 240 GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGD 299
GS+ G G + G +G N G G G G G G
Sbjct: 1164 GSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEP-GPPGP 1222
Query: 300 SGSESSWGSSTGSSSGNHGGS 320
G ++ G G++ S
Sbjct: 1223 PGPPGHLTAALGDIMGHYDES 1243
Score = 34.3 bits (77), Expect = 0.21
Identities = 51/186 (27%), Positives = 62/186 (33%), Gaps = 31/186 (16%)
Query: 195 QGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE-GCTNPP----PSGSGGGSSNSG---- 245
Q GG NFG +G +PG V + G PP P G G G
Sbjct: 98 QTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGP 157
Query: 246 -------------GGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGN 292
G G S G +G + S+ S GS G GS G
Sbjct: 158 QGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVG- 216
Query: 293 SGGSRGDSGSESSWGSS--TG--SSSGNHGGSG--GGNGHKPGCEKPG--NEARGSGESG 344
G RG G + G + TG G+ G G G G + KPG E +G G
Sbjct: 217 PVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPG 276
Query: 345 IQGFRG 350
GF G
Sbjct: 277 EVGFAG 282
>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
sapiens]
Length = 898
Score = 73.9 bits (180), Expect = 2e-13
Identities = 85/289 (29%), Positives = 115/289 (39%), Gaps = 38/289 (13%)
Query: 87 PGFGAADALGNRVGEAAHALGN------TGHEIGRQAEDVIRHGADAVRGSWQGVPGHNG 140
PGFG + N V + G G GR HG G+ G G+ G
Sbjct: 625 PGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGA-NHGGYMNAGAGYGSYGYGG 683
Query: 141 AWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGG 200
T+G + F S GG G G GG G G S+G +G QG + +
Sbjct: 684 NSATAG-YSQFYSNGGHSGNASGGGGGGG--------GGSSG-YGSYYQGDNYN---SPV 730
Query: 201 PPNFGTNTQ--GAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG-SSGS 257
PP Q G +P YGS S+Q + S + SN G G Q G + G
Sbjct: 731 PPKHAGKKQPHGGQQKPSYGSGYQSHQGQ-----QQSYNQSPYSNYGPPQGKQKGYNHGQ 785
Query: 258 GSNGDNNNGSSSGGSSSGSSSGGS------SGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311
GS +N+ +S GG + S SGG SGG+S SGG+ + GS +G +G
Sbjct: 786 GSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSG 845
Query: 312 SSS---GNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNM 357
S G GG N + PG + + S +S QG G+ +M
Sbjct: 846 GGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSS-QGGYGRNADHSM 893
Score = 57.4 bits (137), Expect = 2e-08
Identities = 68/252 (26%), Positives = 89/252 (35%), Gaps = 37/252 (14%)
Query: 164 NPG-GLGTPWVHGYPG-------NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQP 215
NPG G+G P + P GS +G +G +GG N G
Sbjct: 624 NPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGA--------- 674
Query: 216 GYGSVRASNQNEGCTNPPPSGSGGGSSN-SGGGSGSQSGSSGSGS--NGDNNNGSSSGGS 272
GYGS + +GG S N SGGG G GSSG GS GDN N
Sbjct: 675 GYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKH 734
Query: 273 SSGSSSGGSSGGSSGGSSGNSGGSRGDSGSES---SWGSSTGSSSG-NHG---------- 318
+ G S GS S + S ++S ++G G G NHG
Sbjct: 735 AGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSY 794
Query: 319 -GSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRN 377
GGG G E N + G SG + G S N G G G +Y+
Sbjct: 795 NSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGG--SGGGSSYQG 852
Query: 378 SETSPGMFNFDT 389
+ N+++
Sbjct: 853 KQGGYSQSNYNS 864
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.131 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,389,001
Number of Sequences: 37866
Number of extensions: 1399884
Number of successful extensions: 49354
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 944
Number of HSP's successfully gapped in prelim test: 639
Number of HSP's that attempted gapping in prelim test: 8339
Number of HSP's gapped (non-prelim): 13001
length of query: 416
length of database: 18,247,518
effective HSP length: 105
effective length of query: 311
effective length of database: 14,271,588
effective search space: 4438463868
effective search space used: 4438463868
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.