Guide to the Human Genome
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Search of human proteins with 52632383

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|52632383 heterogeneous nuclear ribonucleoprotein L isoform a
[Homo sapiens]
         (589 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|52632383 heterogeneous nuclear ribonucleoprotein L isoform a ...  1233   0.0  
gi|52632385 heterogeneous nuclear ribonucleoprotein L isoform b ...   962   0.0  
gi|217416379 heterogeneous nuclear ribonucleoprotein L-like isof...   557   e-158
gi|20149709 heterogeneous nuclear ribonucleoprotein L-like isofo...   557   e-158
gi|4506243 polypyrimidine tract-binding protein 1 isoform a [Hom...   162   6e-40
gi|14165464 polypyrimidine tract-binding protein 1 isoform b [Ho...   160   4e-39
gi|14165466 polypyrimidine tract-binding protein 1 isoform c [Ho...   156   4e-38
gi|38569466 ROD1 regulator of differentiation 1 [Homo sapiens]        153   4e-37
gi|10863997 polypyrimidine tract binding protein 2 [Homo sapiens]     105   1e-22
gi|28558998 polypyrimidine tract-binding protein 1 isoform d [Ho...    70   7e-12
gi|109452587 family with sequence similarity 98, member B isofor...    60   4e-09
gi|4502565 calpain, small subunit 1 [Homo sapiens]                     55   1e-07
gi|51599151 calpain, small subunit 1 [Homo sapiens]                    55   1e-07
gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens]               55   2e-07
gi|195972866 keratin 10 [Homo sapiens]                                 54   3e-07
gi|55956899 keratin 9 [Homo sapiens]                                   54   5e-07
gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap...    53   7e-07
gi|197209826 chromosome 2 open reading frame 21 isoform 1 [Homo ...    53   9e-07
gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo sapi...    53   9e-07
gi|109255251 loricrin [Homo sapiens]                                   52   1e-06
gi|49574532 glycogen synthase kinase 3 alpha [Homo sapiens]            52   2e-06
gi|56699482 hypothetical protein LOC25940 [Homo sapiens]               51   3e-06
gi|4507741 twist [Homo sapiens]                                        50   4e-06
gi|154091020 leucine-rich repeats and calponin homology (CH) dom...    50   4e-06
gi|31542255 hypothetical protein LOC140706 [Homo sapiens]              50   4e-06
gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]          50   6e-06
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s...    50   6e-06
gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homol...    50   8e-06
gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolo...    50   8e-06
gi|42544153 leukocyte receptor tyrosine kinase isoform 1 precurs...    50   8e-06

>gi|52632383 heterogeneous nuclear ribonucleoprotein L isoform a
           [Homo sapiens]
          Length = 589

 Score = 1233 bits (3190), Expect = 0.0
 Identities = 589/589 (100%), Positives = 589/589 (100%)

Query: 1   MSRRLLPRAEKRRRRLEQRQQPDEQRRRSGAMVKMAAAGGGGGGGRYYGGGSEGGRAPKR 60
           MSRRLLPRAEKRRRRLEQRQQPDEQRRRSGAMVKMAAAGGGGGGGRYYGGGSEGGRAPKR
Sbjct: 1   MSRRLLPRAEKRRRRLEQRQQPDEQRRRSGAMVKMAAAGGGGGGGRYYGGGSEGGRAPKR 60

Query: 61  LKTDNAGDQHGGGGGGGGGAGAAGGGGGGENYDDPHKTPASPVVHIRGLIDGVVEADLVE 120
           LKTDNAGDQHGGGGGGGGGAGAAGGGGGGENYDDPHKTPASPVVHIRGLIDGVVEADLVE
Sbjct: 61  LKTDNAGDQHGGGGGGGGGAGAAGGGGGGENYDDPHKTPASPVVHIRGLIDGVVEADLVE 120

Query: 121 ALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKIS 180
           ALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKIS
Sbjct: 121 ALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKIS 180

Query: 181 RPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDS 240
           RPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDS
Sbjct: 181 RPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDS 240

Query: 241 VQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQGDPGSNP 300
           VQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQGDPGSNP
Sbjct: 241 VQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQGDPGSNP 300

Query: 301 NKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHYEGRRMGPPVGGHRRGPSRYG 360
           NKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHYEGRRMGPPVGGHRRGPSRYG
Sbjct: 301 NKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHYEGRRMGPPVGGHRRGPSRYG 360

Query: 361 PQYGHPPPPPPPPEYGPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPG 420
           PQYGHPPPPPPPPEYGPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPG
Sbjct: 361 PQYGHPPPPPPPPEYGPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPG 420

Query: 421 AAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSKQPAIMPGQSYGLEDGSCSYKDFSES 480
           AAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSKQPAIMPGQSYGLEDGSCSYKDFSES
Sbjct: 421 AAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSKQPAIMPGQSYGLEDGSCSYKDFSES 480

Query: 481 RNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPSSVKVFSGKSE 540
           RNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPSSVKVFSGKSE
Sbjct: 481 RNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPSSVKVFSGKSE 540

Query: 541 RSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQHAS 589
           RSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQHAS
Sbjct: 541 RSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQHAS 589


>gi|52632385 heterogeneous nuclear ribonucleoprotein L isoform b
           [Homo sapiens]
          Length = 456

 Score =  962 bits (2488), Expect = 0.0
 Identities = 456/456 (100%), Positives = 456/456 (100%)

Query: 134 MPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKISRPGDSDDSRSVNS 193
           MPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKISRPGDSDDSRSVNS
Sbjct: 1   MPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKISRPGDSDDSRSVNS 60

Query: 194 VLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDSVQSAQRAKASLNG 253
           VLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDSVQSAQRAKASLNG
Sbjct: 61  VLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDSVQSAQRAKASLNG 120

Query: 254 ADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQGDPGSNPNKRQRQPPLLGDH 313
           ADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQGDPGSNPNKRQRQPPLLGDH
Sbjct: 121 ADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQGDPGSNPNKRQRQPPLLGDH 180

Query: 314 PAEYGGPHGGYHSHYHDEGYGPPPPHYEGRRMGPPVGGHRRGPSRYGPQYGHPPPPPPPP 373
           PAEYGGPHGGYHSHYHDEGYGPPPPHYEGRRMGPPVGGHRRGPSRYGPQYGHPPPPPPPP
Sbjct: 181 PAEYGGPHGGYHSHYHDEGYGPPPPHYEGRRMGPPVGGHRRGPSRYGPQYGHPPPPPPPP 240

Query: 374 EYGPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVD 433
           EYGPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVD
Sbjct: 241 EYGPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVD 300

Query: 434 RAITHLNNNFMFGQKLNVCVSKQPAIMPGQSYGLEDGSCSYKDFSESRNNRFSTPEQAAK 493
           RAITHLNNNFMFGQKLNVCVSKQPAIMPGQSYGLEDGSCSYKDFSESRNNRFSTPEQAAK
Sbjct: 301 RAITHLNNNFMFGQKLNVCVSKQPAIMPGQSYGLEDGSCSYKDFSESRNNRFSTPEQAAK 360

Query: 494 NRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPSSVKVFSGKSERSSSGLLEWESKS 553
           NRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPSSVKVFSGKSERSSSGLLEWESKS
Sbjct: 361 NRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPSSVKVFSGKSERSSSGLLEWESKS 420

Query: 554 DALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQHAS 589
           DALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQHAS
Sbjct: 421 DALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQHAS 456


>gi|217416379 heterogeneous nuclear ribonucleoprotein L-like isoform
           2 [Homo sapiens]
          Length = 537

 Score =  557 bits (1435), Expect = e-158
 Identities = 297/520 (57%), Positives = 367/520 (70%), Gaps = 30/520 (5%)

Query: 71  GGGGGGGGGAGAAGGGGGGENYDDPHKTPASPVVHIRGLIDGVVEADLVEALQEFGPISY 130
           GGG GGGGG   +    GG +    HK   SPVVH+RGL + VVEADLVEAL++FG I Y
Sbjct: 44  GGGDGGGGGRSFSQPEAGGSH----HKVSVSPVVHVRGLCESVVEADLVEALEKFGTICY 99

Query: 131 VVVMPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKISRPGDSDDSRS 190
           V++MP KRQALVEFE++  A   V +AAD  +YIAG  AF NYSTS++I+RPG++DD   
Sbjct: 100 VMMMPFKRQALVEFENIDSAKECVTFAADEPVYIAGQQAFFNYSTSKRITRPGNTDDPSG 159

Query: 191 VNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDSVQSAQRAKAS 250
            N VLL +I NP+Y IT DVLYT+CNP G VQRIVIF++NG+QAMVEF+SV  AQ+AKA+
Sbjct: 160 GNKVLLLSIQNPLYPITVDVLYTVCNPVGKVQRIVIFKRNGIQAMVEFESVLCAQKAKAA 219

Query: 251 LNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQGDPGSNPNKRQRQPPLL 310
           LNGADIY+GCCTLKIEYA+PTRLNV +ND D+WDYT P L G+ D G     RQRQ  +L
Sbjct: 220 LNGADIYAGCCTLKIEYARPTRLNVIRNDNDSWDYTKPYL-GRRDRGKG---RQRQ-AIL 274

Query: 311 GDHPAEYGGPHGGYHSHYHDEGYGPPPPHYEGRRMGPPVGGHRRGPSRYGPQYGHPPPPP 370
           G+HP+ +   H GY SH      GP  P     RMG          SR  P+    P P 
Sbjct: 275 GEHPSSF--RHDGYGSH------GPLLPLPSRYRMG----------SRDTPELVAYPLPQ 316

Query: 371 PPPEY--GPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMAD 428
               Y  G +    V+MV GL Q KMNC RVFN+FCLYGN+EKVKFMK+ PG A+VEM D
Sbjct: 317 ASSSYMHGGNPSGSVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTALVEMGD 376

Query: 429 GYAVDRAITHLNNNFMFGQKLNVCVSKQPAIMPGQSYGLEDGSCSYKDFSESRNNRFSTP 488
            YAV+RA+THLNN  +FG++LNVCVSKQ +++P Q + LEDG+ SYKDF+ S+NNRF++ 
Sbjct: 377 EYAVERAVTHLNNVKLFGKRLNVCVSKQHSVVPSQIFELEDGTSSYKDFAMSKNNRFTSA 436

Query: 489 EQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPSSVKVFSGK-SERSSSGLL 547
            QA+KN IQ PS VLH++N PL VTEE F ++C++  V      KVF  K S ++ SGLL
Sbjct: 437 GQASKNIIQPPSCVLHYYNVPLCVTEETFTKLCNDHEVLTFIKYKVFDAKPSAKTLSGLL 496

Query: 548 EWESKSDALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQH 587
           EWE K+DA+E L  LNHYQ++ PNG  PYTLKLCFST+ H
Sbjct: 497 EWECKTDAVEALTALNHYQIRVPNGSNPYTLKLCFSTSSH 536


>gi|20149709 heterogeneous nuclear ribonucleoprotein L-like isoform
           1 [Homo sapiens]
          Length = 542

 Score =  557 bits (1435), Expect = e-158
 Identities = 297/520 (57%), Positives = 367/520 (70%), Gaps = 30/520 (5%)

Query: 71  GGGGGGGGGAGAAGGGGGGENYDDPHKTPASPVVHIRGLIDGVVEADLVEALQEFGPISY 130
           GGG GGGGG   +    GG +    HK   SPVVH+RGL + VVEADLVEAL++FG I Y
Sbjct: 49  GGGDGGGGGRSFSQPEAGGSH----HKVSVSPVVHVRGLCESVVEADLVEALEKFGTICY 104

Query: 131 VVVMPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKISRPGDSDDSRS 190
           V++MP KRQALVEFE++  A   V +AAD  +YIAG  AF NYSTS++I+RPG++DD   
Sbjct: 105 VMMMPFKRQALVEFENIDSAKECVTFAADEPVYIAGQQAFFNYSTSKRITRPGNTDDPSG 164

Query: 191 VNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDSVQSAQRAKAS 250
            N VLL +I NP+Y IT DVLYT+CNP G VQRIVIF++NG+QAMVEF+SV  AQ+AKA+
Sbjct: 165 GNKVLLLSIQNPLYPITVDVLYTVCNPVGKVQRIVIFKRNGIQAMVEFESVLCAQKAKAA 224

Query: 251 LNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQGDPGSNPNKRQRQPPLL 310
           LNGADIY+GCCTLKIEYA+PTRLNV +ND D+WDYT P L G+ D G     RQRQ  +L
Sbjct: 225 LNGADIYAGCCTLKIEYARPTRLNVIRNDNDSWDYTKPYL-GRRDRGKG---RQRQ-AIL 279

Query: 311 GDHPAEYGGPHGGYHSHYHDEGYGPPPPHYEGRRMGPPVGGHRRGPSRYGPQYGHPPPPP 370
           G+HP+ +   H GY SH      GP  P     RMG          SR  P+    P P 
Sbjct: 280 GEHPSSF--RHDGYGSH------GPLLPLPSRYRMG----------SRDTPELVAYPLPQ 321

Query: 371 PPPEY--GPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMAD 428
               Y  G +    V+MV GL Q KMNC RVFN+FCLYGN+EKVKFMK+ PG A+VEM D
Sbjct: 322 ASSSYMHGGNPSGSVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTALVEMGD 381

Query: 429 GYAVDRAITHLNNNFMFGQKLNVCVSKQPAIMPGQSYGLEDGSCSYKDFSESRNNRFSTP 488
            YAV+RA+THLNN  +FG++LNVCVSKQ +++P Q + LEDG+ SYKDF+ S+NNRF++ 
Sbjct: 382 EYAVERAVTHLNNVKLFGKRLNVCVSKQHSVVPSQIFELEDGTSSYKDFAMSKNNRFTSA 441

Query: 489 EQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPSSVKVFSGK-SERSSSGLL 547
            QA+KN IQ PS VLH++N PL VTEE F ++C++  V      KVF  K S ++ SGLL
Sbjct: 442 GQASKNIIQPPSCVLHYYNVPLCVTEETFTKLCNDHEVLTFIKYKVFDAKPSAKTLSGLL 501

Query: 548 EWESKSDALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQH 587
           EWE K+DA+E L  LNHYQ++ PNG  PYTLKLCFST+ H
Sbjct: 502 EWECKTDAVEALTALNHYQIRVPNGSNPYTLKLCFSTSSH 541


>gi|4506243 polypyrimidine tract-binding protein 1 isoform a [Homo
           sapiens]
          Length = 557

 Score =  162 bits (411), Expect = 6e-40
 Identities = 146/533 (27%), Positives = 238/533 (44%), Gaps = 70/533 (13%)

Query: 80  AGAAGGGGGGENYDDPHKTPASP--VVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKK 137
           + +A  G   + +    ++   P  V+HIR L   V E +++     FG ++ ++++  K
Sbjct: 35  SASAANGNDSKKFKGDSRSAGVPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGK 94

Query: 138 RQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKISRPGDSDDSR------SV 191
            QA +E      A   VNY       + G P ++ +S  +++      + +R      +V
Sbjct: 95  NQAFIEMNTEEAANTMVNYYTSVTPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAV 154

Query: 192 NS--------------------------VLLFTILNPIYSITTDVLYTICNPCGPVQRIV 225
           NS                          VL   + N  Y +T DVL+ I +  G V +I+
Sbjct: 155 NSVQSGNLALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKII 214

Query: 226 IFRKNG-VQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWD 284
            F KN   QA++++    SAQ AK SL+G +IY+ CCTL+I+++K T LNV  N+  + D
Sbjct: 215 TFTKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRD 274

Query: 285 YTNPNLSGQGDPGSNPNKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHYEGRR 344
           YT P+L   GD          QP L     A +G P  G  S     G G PP     + 
Sbjct: 275 YTRPDLP-SGD---------SQPSLDQTMAAAFGAP--GIISASPYAGAGFPPTFAIPQA 322

Query: 345 MGPPVGGHRRGPSRYG--PQYGHPPPPPPPPEYG-------PHADSPVLMVYGLDQSKMN 395
            G  V      P+ +G       P         G         A + VL+V  L+  ++ 
Sbjct: 323 AGLSV------PNVHGALAPLAIPSAAAAAAAAGRIAIPGLAGAGNSVLLVSNLNPERVT 376

Query: 396 CDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSK 455
              +F +F +YG+V++VK + +K   A+V+MADG     A++HLN + + G+ + + +SK
Sbjct: 377 PQSLFILFGVYGDVQRVKILFNKKENALVQMADGNQAQLAMSHLNGHKLHGKPIRITLSK 436

Query: 456 -QPAIMPGQSYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTE 514
            Q   +P +  G ED   + KD+  S  +RF  P       I  PS  LH  N P  V+E
Sbjct: 437 HQNVQLPRE--GQEDQGLT-KDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSE 493

Query: 515 ENFFEICDELGVKRPSSVKVFSGKSERSSSGLLEWESKSDALETLGFLNHYQM 567
           E+   +    G      VK F    +     L++  S  +A++ L  L+++ +
Sbjct: 494 EDLKVLFSSNG----GVVKGFKFFQKDRKMALIQMGSVEEAVQALIDLHNHDL 542



 Score = 30.8 bits (68), Expect = 3.6
 Identities = 36/158 (22%), Positives = 65/158 (41%), Gaps = 29/158 (18%)

Query: 428 DGYAVDRAI-THLNNNFMFGQKLNVCVSKQPAIMPGQSYGLEDGSCSYKDFSESRNNRFS 486
           DG   D A+ T   ++ +F    + CV+  P IM   S    +G+ S K   +SR+    
Sbjct: 2   DGIVPDIAVGTKRGSDELF----STCVTNGPFIMSSNSASAANGNDSKKFKGDSRSAGV- 56

Query: 487 TPEQAAKNRIQHPSNVLHFFNAPLEVTEEN-------FFEICDELGVKRPSSVKVFSGKS 539
                       PS V+H    P++VTE         F ++ + L +K  +   +     
Sbjct: 57  ------------PSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTE 104

Query: 540 ERSSSGLLEWESKSDALE----TLGFLNHYQMKNPNGP 573
           E +++ +  + S +  L      + F NH ++K  + P
Sbjct: 105 EAANTMVNYYTSVTPVLRGQPIYIQFSNHKELKTDSSP 142


>gi|14165464 polypyrimidine tract-binding protein 1 isoform b [Homo
           sapiens]
          Length = 550

 Score =  160 bits (404), Expect = 4e-39
 Identities = 143/533 (26%), Positives = 236/533 (44%), Gaps = 77/533 (14%)

Query: 80  AGAAGGGGGGENYDDPHKTPASP--VVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKK 137
           + +A  G   + +    ++   P  V+HIR L   V E +++     FG ++ ++++  K
Sbjct: 35  SASAANGNDSKKFKGDSRSAGVPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGK 94

Query: 138 RQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKISRPGDSDDSR------SV 191
            QA +E      A   VNY       + G P ++ +S  +++      + +R      +V
Sbjct: 95  NQAFIEMNTEEAANTMVNYYTSVTPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAV 154

Query: 192 NS--------------------------VLLFTILNPIYSITTDVLYTICNPCGPVQRIV 225
           NS                          VL   + N  Y +T DVL+ I +  G V +I+
Sbjct: 155 NSVQSGNLALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKII 214

Query: 226 IFRKNG-VQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWD 284
            F KN   QA++++    SAQ AK SL+G +IY+ CCTL+I+++K T LNV  N+  + D
Sbjct: 215 TFTKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRD 274

Query: 285 YTNPNLSGQGDPGSNPNKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHYEGRR 344
           YT P+L   GD          QP L     A +  P+          G G PP     + 
Sbjct: 275 YTRPDLP-SGD---------SQPSLDQTMAAAFASPYA---------GAGFPPTFAIPQA 315

Query: 345 MGPPVGGHRRGPSRYG--PQYGHPPPPPPPPEYG-------PHADSPVLMVYGLDQSKMN 395
            G  V      P+ +G       P         G         A + VL+V  L+  ++ 
Sbjct: 316 AGLSV------PNVHGALAPLAIPSAAAAAAAAGRIAIPGLAGAGNSVLLVSNLNPERVT 369

Query: 396 CDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSK 455
              +F +F +YG+V++VK + +K   A+V+MADG     A++HLN + + G+ + + +SK
Sbjct: 370 PQSLFILFGVYGDVQRVKILFNKKENALVQMADGNQAQLAMSHLNGHKLHGKPIRITLSK 429

Query: 456 -QPAIMPGQSYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTE 514
            Q   +P +  G ED   + KD+  S  +RF  P       I  PS  LH  N P  V+E
Sbjct: 430 HQNVQLPRE--GQEDQGLT-KDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSE 486

Query: 515 ENFFEICDELGVKRPSSVKVFSGKSERSSSGLLEWESKSDALETLGFLNHYQM 567
           E+   +    G      VK F    +     L++  S  +A++ L  L+++ +
Sbjct: 487 EDLKVLFSSNG----GVVKGFKFFQKDRKMALIQMGSVEEAVQALIDLHNHDL 535



 Score = 30.8 bits (68), Expect = 3.6
 Identities = 36/158 (22%), Positives = 65/158 (41%), Gaps = 29/158 (18%)

Query: 428 DGYAVDRAI-THLNNNFMFGQKLNVCVSKQPAIMPGQSYGLEDGSCSYKDFSESRNNRFS 486
           DG   D A+ T   ++ +F    + CV+  P IM   S    +G+ S K   +SR+    
Sbjct: 2   DGIVPDIAVGTKRGSDELF----STCVTNGPFIMSSNSASAANGNDSKKFKGDSRSAGV- 56

Query: 487 TPEQAAKNRIQHPSNVLHFFNAPLEVTEEN-------FFEICDELGVKRPSSVKVFSGKS 539
                       PS V+H    P++VTE         F ++ + L +K  +   +     
Sbjct: 57  ------------PSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTE 104

Query: 540 ERSSSGLLEWESKSDALE----TLGFLNHYQMKNPNGP 573
           E +++ +  + S +  L      + F NH ++K  + P
Sbjct: 105 EAANTMVNYYTSVTPVLRGQPIYIQFSNHKELKTDSSP 142


>gi|14165466 polypyrimidine tract-binding protein 1 isoform c [Homo
           sapiens]
          Length = 531

 Score =  156 bits (395), Expect = 4e-38
 Identities = 138/524 (26%), Positives = 227/524 (43%), Gaps = 78/524 (14%)

Query: 80  AGAAGGGGGGENYDDPHKTPASP--VVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKK 137
           + +A  G   + +    ++   P  V+HIR L   V E +++     FG ++ ++++  K
Sbjct: 35  SASAANGNDSKKFKGDSRSAGVPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGK 94

Query: 138 RQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKISRPGDSDDSR------SV 191
            QA +E      A   VNY       + G P ++ +S  +++      + +R      +V
Sbjct: 95  NQAFIEMNTEEAANTMVNYYTSVTPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAV 154

Query: 192 NS--------------------------VLLFTILNPIYSITTDVLYTICNPCGPVQRIV 225
           NS                          VL   + N  Y +T DVL+ I +  G V +I+
Sbjct: 155 NSVQSGNLALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKII 214

Query: 226 IFRKNG-VQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWD 284
            F KN   QA++++    SAQ AK SL+G +IY+ CCTL+I+++K T LNV  N+  + D
Sbjct: 215 TFTKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRD 274

Query: 285 YTNPNLSGQGDPGSNPNKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHYEGRR 344
           YT P+L   GD  S P+  Q      G         HG              P       
Sbjct: 275 YTRPDLP-SGD--SQPSLDQTMAAAFG---LSVPNVHGAL-----------APLAIPSAA 317

Query: 345 MGPPVGGHRRGPSRYGPQYGHPPPPPPPPEYGPHADSPVLMVYGLDQSKMNCDRVFNVFC 404
                 G    P   G                  A + VL+V  L+  ++    +F +F 
Sbjct: 318 AAAAAAGRIAIPGLAG------------------AGNSVLLVSNLNPERVTPQSLFILFG 359

Query: 405 LYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSK-QPAIMPGQ 463
           +YG+V++VK + +K   A+V+MADG     A++HLN + + G+ + + +SK Q   +P +
Sbjct: 360 VYGDVQRVKILFNKKENALVQMADGNQAQLAMSHLNGHKLHGKPIRITLSKHQNVQLPRE 419

Query: 464 SYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDE 523
             G ED   + KD+  S  +RF  P       I  PS  LH  N P  V+EE+   +   
Sbjct: 420 --GQEDQGLT-KDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEEDLKVLFSS 476

Query: 524 LGVKRPSSVKVFSGKSERSSSGLLEWESKSDALETLGFLNHYQM 567
            G      VK F    +     L++  S  +A++ L  L+++ +
Sbjct: 477 NG----GVVKGFKFFQKDRKMALIQMGSVEEAVQALIDLHNHDL 516



 Score = 30.8 bits (68), Expect = 3.6
 Identities = 36/158 (22%), Positives = 65/158 (41%), Gaps = 29/158 (18%)

Query: 428 DGYAVDRAI-THLNNNFMFGQKLNVCVSKQPAIMPGQSYGLEDGSCSYKDFSESRNNRFS 486
           DG   D A+ T   ++ +F    + CV+  P IM   S    +G+ S K   +SR+    
Sbjct: 2   DGIVPDIAVGTKRGSDELF----STCVTNGPFIMSSNSASAANGNDSKKFKGDSRSAGV- 56

Query: 487 TPEQAAKNRIQHPSNVLHFFNAPLEVTEEN-------FFEICDELGVKRPSSVKVFSGKS 539
                       PS V+H    P++VTE         F ++ + L +K  +   +     
Sbjct: 57  ------------PSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTE 104

Query: 540 ERSSSGLLEWESKSDALE----TLGFLNHYQMKNPNGP 573
           E +++ +  + S +  L      + F NH ++K  + P
Sbjct: 105 EAANTMVNYYTSVTPVLRGQPIYIQFSNHKELKTDSSP 142


>gi|38569466 ROD1 regulator of differentiation 1 [Homo sapiens]
          Length = 552

 Score =  153 bits (387), Expect = 4e-37
 Identities = 134/506 (26%), Positives = 226/506 (44%), Gaps = 55/506 (10%)

Query: 97  KTPASP--VVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQALVEFEDVLGACNAV 154
           + P SP  V+H+R +   V EA+++     FG ++ ++++  K QA +E      A   V
Sbjct: 52  RPPCSPSRVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMV 111

Query: 155 NYAADNQIYIAGHPAFVNYSTSQKISRPGDSDDSRSV----------------------- 191
           NY      ++   P ++ YS  +++      + +R+                        
Sbjct: 112 NYYTPITPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNE 171

Query: 192 -------NSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNG-VQAMVEFDSVQS 243
                  + VL   I N  Y +T +VL+ I +  G V +I+ F KN   QA++++    +
Sbjct: 172 GTVLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVN 231

Query: 244 AQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNL-SGQGDPGSNPNK 302
           A  AK +L+G +IY+ CCTL+I+++K T LNV  N+  + D+T  +L +G G P      
Sbjct: 232 AHYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSL---- 287

Query: 303 RQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHYEGRRMGPPVGGHRRGPSRYGPQ 362
              +PP+     A +G P      +    G+ P     +   +  P      GP      
Sbjct: 288 ---EPPMA----AAFGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTITSS 340

Query: 363 YGHPPPPPPPPEYGPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGAA 422
                   P     P   + VL+V  L+   +    +F +F +YG+V +VK M +K   A
Sbjct: 341 AVTGRMAIPGASGIP--GNSVLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENA 398

Query: 423 MVEMADGYAVDRAITHLNNNFMFGQKLNVCVSKQPAI-MPGQSYGLEDGSCSYKDFSESR 481
           +V+MAD      A+ HL+   ++G+ L   +SK  A+ +P +  G ED   + KDFS S 
Sbjct: 399 LVQMADANQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPRE--GQEDQGLT-KDFSNSP 455

Query: 482 NNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPSSVKVFSGKSER 541
            +RF  P       I  PS  LH  N P  VT ++   +  E G     SVK F    + 
Sbjct: 456 LHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTVDDLKNLFIEAG----CSVKAFKFFQKD 511

Query: 542 SSSGLLEWESKSDALETLGFLNHYQM 567
               L++  S  +A++ L  L+++ +
Sbjct: 512 RKMALIQLGSVEEAIQALIELHNHDL 537



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 37/171 (21%), Positives = 69/171 (40%), Gaps = 25/171 (14%)

Query: 125 FGPISYVVVM-PKKRQALVEFEDVLGACNAVNYAADNQIY-------IAGHPAF------ 170
           +G +  V +M  KK  ALV+  D   A  A+N+ +  ++Y       ++ H A       
Sbjct: 382 YGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREG 441

Query: 171 ---------VNYSTSQKISRPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCG-P 220
                     + S   +  +PG  +            + N   S+T D L  +    G  
Sbjct: 442 QEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTVDDLKNLFIEAGCS 501

Query: 221 VQRIVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPT 271
           V+    F+K+   A+++  SV+ A +A   L+  D+      L++ ++K T
Sbjct: 502 VKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGEN-HHLRVSFSKST 551


>gi|10863997 polypyrimidine tract binding protein 2 [Homo sapiens]
          Length = 531

 Score =  105 bits (262), Expect = 1e-22
 Identities = 70/248 (28%), Positives = 120/248 (48%), Gaps = 33/248 (13%)

Query: 86  GGGGENYDDPHKTPASP--VVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQALVE 143
           G   + +    K   +P  V+HIR L   V E +++     FG ++ ++++  K QA +E
Sbjct: 41  GNDSKKFKGEDKMDGAPSRVLHIRKLPGEVTETEVIALGLPFGKVTNILMLKGKNQAFLE 100

Query: 144 FEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKI------------------------ 179
                 A   VNY +    ++   P ++ YS  +++                        
Sbjct: 101 LATEEAAITMVNYYSAVTPHLRNQPIYIQYSNHKELKTDNTLNQRAQAVLQAVTAVQTAN 160

Query: 180 -----SRPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNG-VQ 233
                +   +S  + + + VL   I N  Y +T DVL+ I +  G V +I+ F KN   Q
Sbjct: 161 TPLSGTTVSESAVTPAQSPVLRIIIDNMYYPVTLDVLHQIFSKFGAVLKIITFTKNNQFQ 220

Query: 234 AMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNL-SG 292
           A++++    +AQ+AK +L+G +IY+ CCTL+I+++K   LNV  N+  + DYT P+L SG
Sbjct: 221 ALLQYGDPVNAQQAKLALDGQNIYNACCTLRIDFSKLVNLNVKYNNDKSRDYTRPDLPSG 280

Query: 293 QGDPGSNP 300
            G P  +P
Sbjct: 281 DGQPALDP 288



 Score = 84.0 bits (206), Expect = 4e-16
 Identities = 57/186 (30%), Positives = 97/186 (52%), Gaps = 9/186 (4%)

Query: 383 VLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNN 442
           VL+V  L++  +    +F +F +YG+V++VK + +K  +A+++MADG     A+ HLN  
Sbjct: 339 VLLVSNLNEEMVTPQSLFTLFGVYGDVQRVKILYNKKDSALIQMADGNQSQLAMNHLNGQ 398

Query: 443 FMFGQKLNVCVSKQPAI-MPGQSYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSN 501
            M+G+ + V +SK   + +P +  GL+D   + KDF  S  +RF  P       I  PS 
Sbjct: 399 KMYGKIIRVTLSKHQTVQLPRE--GLDDQGLT-KDFGNSPLHRFKKPGSKNFQNIFPPSA 455

Query: 502 VLHFFNAPLEVTEENFFEICDELGVKRPSSVKVFSGKSERSSSGLLEWESKSDALETLGF 561
            LH  N P  V EE+   +    G     +VK F    +   + LL+  +  +A++ L  
Sbjct: 456 TLHLSNIPPSVAEEDLRTLFANTG----GTVKAFKFFQDHKMA-LLQMATVEEAIQALID 510

Query: 562 LNHYQM 567
           L++Y +
Sbjct: 511 LHNYNL 516



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 7/122 (5%)

Query: 181 RPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDS 240
           R G    S   N+VLL + LN    +T   L+T+    G VQR+ I       A+++   
Sbjct: 326 RVGMPGVSAGGNTVLLVSNLNE-EMVTPQSLFTLFGVYGDVQRVKILYNKKDSALIQMAD 384

Query: 241 VQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQD----TWDYTNPNLSGQGDP 296
              +Q A   LNG  +Y     +++  +K   + + +   D    T D+ N  L     P
Sbjct: 385 GNQSQLAMNHLNGQKMYGK--IIRVTLSKHQTVQLPREGLDDQGLTKDFGNSPLHRFKKP 442

Query: 297 GS 298
           GS
Sbjct: 443 GS 444


>gi|28558998 polypyrimidine tract-binding protein 1 isoform d [Homo
           sapiens]
          Length = 197

 Score = 69.7 bits (169), Expect = 7e-12
 Identities = 51/170 (30%), Positives = 87/170 (51%), Gaps = 8/170 (4%)

Query: 399 VFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSK-QP 457
           +F +F +YG+V++VK + +K   A+V+MADG     A++HLN + + G+ + + +SK Q 
Sbjct: 20  LFILFGVYGDVQRVKILFNKKENALVQMADGNQAQLAMSHLNGHKLHGKPIRITLSKHQN 79

Query: 458 AIMPGQSYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENF 517
             +P +  G ED   + KD+  S  +RF  P       I  PS  LH  N P  V+EE+ 
Sbjct: 80  VQLPRE--GQEDQGLT-KDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEEDL 136

Query: 518 FEICDELGVKRPSSVKVFSGKSERSSSGLLEWESKSDALETLGFLNHYQM 567
             +    G      VK F    +     L++  S  +A++ L  L+++ +
Sbjct: 137 KVLFSSNG----GVVKGFKFFQKDRKMALIQMGSVEEAVQALIDLHNHDL 182



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 26/97 (26%), Positives = 42/97 (43%), Gaps = 6/97 (6%)

Query: 206 ITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKI 265
           +T   L+ +    G VQR+ I       A+V+      AQ A + LNG  ++     ++I
Sbjct: 15  VTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGNQAQLAMSHLNGHKLHGK--PIRI 72

Query: 266 EYAKPTRLNVFKNDQD----TWDYTNPNLSGQGDPGS 298
             +K   + + +  Q+    T DY N  L     PGS
Sbjct: 73  TLSKHQNVQLPREGQEDQGLTKDYGNSPLHRFKKPGS 109


>gi|109452587 family with sequence similarity 98, member B isoform 1
           [Homo sapiens]
          Length = 433

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 34/70 (48%), Positives = 38/70 (54%), Gaps = 5/70 (7%)

Query: 20  QQPDEQRRRSGAMVKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGG 79
           + P  Q+R+ G   +    GGGGGGGR  GGG  GGR          G   GGGGGGGGG
Sbjct: 321 EMPPWQKRQEGGGGRGGWGGGGGGGGRG-GGGGGGGRGG----WGGGGGGWGGGGGGGGG 375

Query: 80  AGAAGGGGGG 89
            G  GGGG G
Sbjct: 376 WGGGGGGGRG 385



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 30/67 (44%), Positives = 33/67 (49%), Gaps = 13/67 (19%)

Query: 39  GGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGG-------------GGGGGGAGAAGG 85
           GGGGGGG  +GGG  GGR   + + D  G    GG             GGGGGG G  GG
Sbjct: 367 GGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGG 426

Query: 86  GGGGENY 92
           GGG   Y
Sbjct: 427 GGGYRRY 433


>gi|4502565 calpain, small subunit 1 [Homo sapiens]
          Length = 268

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 30/57 (52%), Positives = 32/57 (56%), Gaps = 3/57 (5%)

Query: 32 MVKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGG 88
          +V     GGGGGGG   GGG  GG     L    +G   GGGGGGGGG G  GGGGG
Sbjct: 3  LVNSFLKGGGGGGG---GGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGG 56



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 23/53 (43%), Positives = 26/53 (49%)

Query: 31 AMVKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAA 83
          + +K    GGGGGGG   G G+  G           G   GGGGGGGGG G A
Sbjct: 6  SFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTA 58



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 25/57 (43%), Positives = 26/57 (45%), Gaps = 3/57 (5%)

Query: 35 MAAAGGGGGGGRYYGGGSE---GGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGG 88
          +   GGGGGGG   GGG     GG           G   GGGGGGGGG  A    GG
Sbjct: 8  LKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGG 64



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 15/32 (46%), Positives = 17/32 (53%)

Query: 30 GAMVKMAAAGGGGGGGRYYGGGSEGGRAPKRL 61
          G +      GGGGGGG   GGG  GG A + L
Sbjct: 31 GLISGAGGGGGGGGGGGGGGGGGGGGTAMRIL 62


>gi|51599151 calpain, small subunit 1 [Homo sapiens]
          Length = 268

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 30/57 (52%), Positives = 32/57 (56%), Gaps = 3/57 (5%)

Query: 32 MVKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGG 88
          +V     GGGGGGG   GGG  GG     L    +G   GGGGGGGGG G  GGGGG
Sbjct: 3  LVNSFLKGGGGGGG---GGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGG 56



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 23/53 (43%), Positives = 26/53 (49%)

Query: 31 AMVKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAA 83
          + +K    GGGGGGG   G G+  G           G   GGGGGGGGG G A
Sbjct: 6  SFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTA 58



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 25/57 (43%), Positives = 26/57 (45%), Gaps = 3/57 (5%)

Query: 35 MAAAGGGGGGGRYYGGGSE---GGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGG 88
          +   GGGGGGG   GGG     GG           G   GGGGGGGGG  A    GG
Sbjct: 8  LKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGG 64



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 15/32 (46%), Positives = 17/32 (53%)

Query: 30 GAMVKMAAAGGGGGGGRYYGGGSEGGRAPKRL 61
          G +      GGGGGGG   GGG  GG A + L
Sbjct: 31 GLISGAGGGGGGGGGGGGGGGGGGGGTAMRIL 62


>gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens]
          Length = 332

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 41/123 (33%), Positives = 56/123 (45%), Gaps = 23/123 (18%)

Query: 33  VKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGGENY 92
           + +A++GGG G G   GGG+ GG               GG G GGGGAG AGGGGGG + 
Sbjct: 27  ILLASSGGGNGAGG--GGGAGGGSG-------------GGNGAGGGGAGGAGGGGGGGSR 71

Query: 93  DDPHKTPASPVVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQALVEFEDVLGACN 152
             P +     +  +    + V  A + E L+E G I       +  + L       GAC 
Sbjct: 72  APPEELSMFQLPTLNFSPEQV--ASVCETLEETGDIE------RLGRFLWSLPVAPGACE 123

Query: 153 AVN 155
           A+N
Sbjct: 124 AIN 126


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 25/56 (44%), Positives = 31/56 (55%)

Query: 37  AAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGGENY 92
           ++GGGG GG  +GGG  GG +         G  HGG  GGG G G++GGG  G  Y
Sbjct: 458 SSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGY 513



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 30/77 (38%), Positives = 38/77 (49%), Gaps = 4/77 (5%)

Query: 29  SGAMVKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGA----GAAG 84
           SG      ++GGG  GG Y GG S GG           G   GGGGG GGG+     ++G
Sbjct: 495 SGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSG 554

Query: 85  GGGGGENYDDPHKTPAS 101
           GG GG +    HK+ +S
Sbjct: 555 GGYGGGSSSGGHKSSSS 571



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 32/82 (39%), Positives = 42/82 (51%), Gaps = 4/82 (4%)

Query: 19  RQQPDEQRRRSGAMVKMAAAGGGGGGGRY---YGGGSEGGRAPKRLKTDNAGDQHGGG-G 74
           R + + Q  RS    + ++ GGG GGG +   YGGGS GG +         G   GGG G
Sbjct: 441 RLENEIQTYRSLLEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYG 500

Query: 75  GGGGGAGAAGGGGGGENYDDPH 96
           GG  G G++GGG GG +    H
Sbjct: 501 GGSSGGGSSGGGYGGGSSSGGH 522



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 23/50 (46%), Positives = 28/50 (56%)

Query: 40  GGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGG 89
           GG  GG Y GG S GG +       ++   HGG   GG G G++GGGGGG
Sbjct: 492 GGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGG 541



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 23/52 (44%), Positives = 26/52 (50%)

Query: 37  AAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGG 88
           ++GGG GGG   GG S GG         + G   GG GGG  G G  G GGG
Sbjct: 494 SSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGG 545



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 23/54 (42%), Positives = 26/54 (48%)

Query: 38  AGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGGEN 91
           + GGG GG   GGGS GG       +   G    GG GGG   G  GG GGG +
Sbjct: 494 SSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSS 547



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 22/53 (41%), Positives = 25/53 (47%)

Query: 39  GGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGGEN 91
           GGG  GG   GGG  GG           G   GG  GGG G G++ GG GG +
Sbjct: 474 GGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSS 526



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 32/85 (37%), Positives = 39/85 (45%), Gaps = 11/85 (12%)

Query: 41  GGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGGENYDDPHKTPA 100
           GG  G  +GGGS GG +         G   GGGG GGGG G   GGG G    D      
Sbjct: 95  GGSYGGSFGGGSFGGGS-------FGGGSFGGGGFGGGGFGGGFGGGFG---GDGGLLSG 144

Query: 101 SPVVHIRGLIDGVVE-ADLVEALQE 124
           +  V ++ L D +    D V AL+E
Sbjct: 145 NEKVTMQNLNDRLASYLDKVRALEE 169



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 23/61 (37%), Positives = 25/61 (40%), Gaps = 11/61 (18%)

Query: 39  GGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGGENYDDPHKT 98
           G  GGGG  YGGGS GG           G   GGG GGG  +G       G   +   K 
Sbjct: 533 GSSGGGGGGYGGGSSGG-----------GSSSGGGYGGGSSSGGHKSSSSGSVGESSSKG 581

Query: 99  P 99
           P
Sbjct: 582 P 582



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 25/69 (36%), Positives = 29/69 (42%), Gaps = 8/69 (11%)

Query: 29  SGAMVKMAAAGGG---GGGGRY-----YGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGA 80
           SG      ++GGG   G  G Y     +GGGS  G         + G   GGG  GGG  
Sbjct: 53  SGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSF 112

Query: 81  GAAGGGGGG 89
           G    GGGG
Sbjct: 113 GGGSFGGGG 121



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 24/67 (35%), Positives = 31/67 (46%), Gaps = 8/67 (11%)

Query: 26 RRRSGAMVKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGG---GGGGGGAGA 82
          R  S      + +GGGGG     GGG  GG     L+  ++    GGG   GG  GG+ +
Sbjct: 4  RYSSSKHYSSSRSGGGGG-----GGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFS 58

Query: 83 AGGGGGG 89
           G  GGG
Sbjct: 59 RGSSGGG 65



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 24/65 (36%), Positives = 28/65 (43%), Gaps = 1/65 (1%)

Query: 26  RRRSGAMVKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGG-GAGAAG 84
           R  SG      ++GG GG G + GG   G            G   GG  GGG  G G+ G
Sbjct: 59  RGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFG 118

Query: 85  GGGGG 89
           GGG G
Sbjct: 119 GGGFG 123



 Score = 36.6 bits (83), Expect = 0.066
 Identities = 22/53 (41%), Positives = 24/53 (45%), Gaps = 3/53 (5%)

Query: 40  GGGGGGRY---YGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGG 89
           GG GGG +   YG  S GG         + G    GGG  GGG    GG GGG
Sbjct: 78  GGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGG 130



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 26/78 (33%), Positives = 30/78 (38%), Gaps = 16/78 (20%)

Query: 28 RSGAMVKMAAAGGGGG-------------GGRYYGGGSEGGRAPKRLKTDNAGDQHGGGG 74
          RSG        GGGGG             GG +  GG  GG   +     + G   GG  
Sbjct: 15 RSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRG---SSGGGCFGGSS 71

Query: 75 GGGGGAGAAGGGGGGENY 92
          GG GG G  GGG    +Y
Sbjct: 72 GGYGGLGGFGGGSFRGSY 89



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 20/50 (40%), Positives = 21/50 (42%), Gaps = 17/50 (34%)

Query: 39  GGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGG 88
           GGG  GG  +GGG                   GGGG GGG  G  GG GG
Sbjct: 108 GGGSFGGGSFGGGG-----------------FGGGGFGGGFGGGFGGDGG 140


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 27/54 (50%), Positives = 32/54 (59%), Gaps = 8/54 (14%)

Query: 38  AGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGG--GGGAGAAGGGGGG 89
           +G GGG G  YGGGS GG +        +G  H GG GG  GGG+G+ GG GGG
Sbjct: 524 SGSGGGSGGGYGGGSGGGHS------GGSGGGHSGGSGGNYGGGSGSGGGSGGG 571



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 26/62 (41%), Positives = 30/62 (48%)

Query: 28  RSGAMVKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGG 87
           R G+         GG GG Y GGGS GG          +G  +GGG G GGG+G   GGG
Sbjct: 478 RGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGG 537

Query: 88  GG 89
            G
Sbjct: 538 SG 539



 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 27/54 (50%), Positives = 30/54 (55%), Gaps = 1/54 (1%)

Query: 39  GGGGGGGRYYGG-GSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGGEN 91
           GGGG GG Y GG GS GG          +G   GGG GGG G G +GG GGG +
Sbjct: 498 GGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHS 551



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 26/60 (43%), Positives = 31/60 (51%)

Query: 30  GAMVKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGG 89
           G   ++   GGGG  G  YGGGS GG +   L     G   G GG  GGG  ++GG GGG
Sbjct: 55  GGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGG 114



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 28/61 (45%), Positives = 36/61 (59%), Gaps = 7/61 (11%)

Query: 34 KMAAAGGGGGGGRY-----YGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGG 88
          + +++GGGGGGGR+     YGGGS   R   R    + G  +GGG GGG  A + GGG G
Sbjct: 34 RFSSSGGGGGGGRFSSSSGYGGGS--SRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFG 91

Query: 89 G 89
          G
Sbjct: 92 G 92



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 28/69 (40%), Positives = 32/69 (46%), Gaps = 2/69 (2%)

Query: 26  RRRSGAMVKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGG--GGAGAA 83
           R  SG       +GGG GGG    GGS G           +G  +GGG GGG  GG+G  
Sbjct: 490 RGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGG 549

Query: 84  GGGGGGENY 92
             GG G NY
Sbjct: 550 HSGGSGGNY 558



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 25/53 (47%), Positives = 29/53 (54%), Gaps = 13/53 (24%)

Query: 39  GGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGG---GGGAGAAGGGGG 88
           GG GG G  YG GS GG          +G  +GGGG G   GGG+G+ GG GG
Sbjct: 476 GGRGGSGGSYGRGSRGG----------SGGSYGGGGSGGGYGGGSGSRGGSGG 518



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 23/50 (46%), Positives = 27/50 (54%)

Query: 38  AGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGG 87
           +GG  GGG   GGGS GG          +G  HGGG G GG +G + GGG
Sbjct: 554 SGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGG 603



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 29/67 (43%), Positives = 33/67 (49%), Gaps = 6/67 (8%)

Query: 29  SGAMVKMAAAGGG-GGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGG-----GGAGA 82
           SG     ++ GGG GGG R +GG S GG +         G   GGG GGG     GG G 
Sbjct: 77  SGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGG 136

Query: 83  AGGGGGG 89
            GGG GG
Sbjct: 137 FGGGAGG 143



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 24/61 (39%), Positives = 29/61 (47%)

Query: 36  AAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGGENYDDP 95
           + +GGG GGG   G GS GG           G + GG  GGG  A  +GGG GG +    
Sbjct: 562 SGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKSS 621

Query: 96  H 96
           H
Sbjct: 622 H 622



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 25/52 (48%), Positives = 29/52 (55%), Gaps = 4/52 (7%)

Query: 39  GGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGG--GGGAGAAGGGGG 88
           GGG GGG  + GGS GG +         G   GGG GG  GGG+G+ GG GG
Sbjct: 535 GGGSGGG--HSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGG 584



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 24/54 (44%), Positives = 29/54 (53%), Gaps = 10/54 (18%)

Query: 38  AGGG--GGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGG 89
           +GGG  GG G  YGGGS  G          +G  +GGG G  GG+G + GGG G
Sbjct: 546 SGGGHSGGSGGNYGGGSGSG--------GGSGGGYGGGSGSRGGSGGSHGGGSG 591



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 9/57 (15%)

Query: 35 MAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGGEN 91
          ++ +GGGGGGG   GG          +++  +     GGGGGGG   ++ G GGG +
Sbjct: 11 LSRSGGGGGGGLGSGGS---------IRSSYSRFSSSGGGGGGGRFSSSSGYGGGSS 58



 Score = 33.1 bits (74), Expect = 0.73
 Identities = 19/63 (30%), Positives = 24/63 (38%), Gaps = 14/63 (22%)

Query: 30  GAMVKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGG 89
           G       +GG  GGG  +GG S              G  +GGG    G  G  GGG G 
Sbjct: 574 GGSGSRGGSGGSHGGGSGFGGES--------------GGSYGGGEEASGSGGGYGGGSGK 619

Query: 90  ENY 92
            ++
Sbjct: 620 SSH 622


>gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo
           sapiens]
          Length = 378

 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 32/83 (38%), Positives = 38/83 (45%), Gaps = 15/83 (18%)

Query: 11  KRRRRLEQRQQPDEQRRRSGAMVKMAAAGG--GGGGGRYYGGGSEGGRAPKRLKTDNAGD 68
           K+    ++ Q    QR R G        GG  GGGGG +  GG+ GGR            
Sbjct: 199 KKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRG----------- 247

Query: 69  QHGGGGGGGGGAGAAGGGGGGEN 91
             G GGGGGG  G+ GGG GG N
Sbjct: 248 --GYGGGGGGSRGSYGGGDGGYN 268



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 27/76 (35%), Positives = 32/76 (42%), Gaps = 9/76 (11%)

Query: 28  RSGAMVKMAAAGGGGGGGR---------YYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGG 78
           R G        GGGGGG R         Y G G +GG         + G   GGG G G 
Sbjct: 239 RGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGN 298

Query: 79  GAGAAGGGGGGENYDD 94
             G  GGGGG + Y++
Sbjct: 299 QGGGYGGGGGYDGYNE 314



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 30/72 (41%), Positives = 32/72 (44%), Gaps = 25/72 (34%)

Query: 39  GGGGGGGRYYGG------GSEGGRAPKRLKTDNAGDQHGGGGGGGG----------GAGA 82
           G GG GG Y GG      G  GG  P        G+Q GG GGGGG          G G 
Sbjct: 269 GFGGDGGNYGGGPGYSSRGGYGGGGP------GYGNQGGGYGGGGGYDGYNEGGNFGGGN 322

Query: 83  AGGGGGGENYDD 94
            GGGG   NY+D
Sbjct: 323 YGGGG---NYND 331



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 26/64 (40%), Positives = 30/64 (46%), Gaps = 26/64 (40%)

Query: 39  GGG--GGGGRY-------------YG---GGSEGGRAPKRLKTDNAGDQHGGGGGGGGGA 80
           GGG  GGGG Y             YG   GGS GGR+        +G  +GGG G GGG+
Sbjct: 319 GGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRS--------SGSPYGGGYGSGGGS 370

Query: 81  GAAG 84
           G  G
Sbjct: 371 GGYG 374



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 1/45 (2%)

Query: 49  GGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGG-GGGGENY 92
           G   E  +A  + +  +AG Q G GGG G   G  G  GGGG N+
Sbjct: 193 GHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNF 237



 Score = 30.8 bits (68), Expect = 3.6
 Identities = 25/82 (30%), Positives = 28/82 (34%), Gaps = 41/82 (50%)

Query: 39  GGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGG---------------------- 76
           GGG GGG  Y G +EGG         N G  + GGGG                       
Sbjct: 300 GGGYGGGGGYDGYNEGG---------NFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGS 350

Query: 77  ----------GGGAGAAGGGGG 88
                     GGG G+ GG GG
Sbjct: 351 FGGRSSGSPYGGGYGSGGGSGG 372


>gi|197209826 chromosome 2 open reading frame 21 isoform 1 [Homo
           sapiens]
          Length = 3258

 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 15/109 (13%)

Query: 5   LLPRAEKRRRRLEQRQQPDEQRRRSGAMVKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTD 64
           ++P  EK R++ E ++    ++R S    +     G    G  +GG +  G         
Sbjct: 688 VVPCVEKNRKKSENKENETLEKRPSEGAFQFKGVSGSSTCG--FGGPAVSGAG------- 738

Query: 65  NAGDQHGGGGGGGGGAGAAGGGGGG------ENYDDPHKTPASPVVHIR 107
           + G + GGGG GGGG G  GGGGGG      +N  +  K  ++PV + R
Sbjct: 739 DGGGEEGGGGDGGGGGGDGGGGGGGGGGPYEKNDKNQEKDESTPVSNHR 787


>gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo
           sapiens]
          Length = 305

 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 31/63 (49%), Positives = 35/63 (55%), Gaps = 8/63 (12%)

Query: 38  AGGGGGGGRYYGGGSEG-----GRAPKRLKTDNAG--DQHGG-GGGGGGGAGAAGGGGGG 89
           +GGGGGG R   GG  G     GR    L     G  + +GG GGGGGGG  A GGGGGG
Sbjct: 181 SGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGGGG 240

Query: 90  ENY 92
            +Y
Sbjct: 241 SSY 243



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 27/67 (40%), Positives = 29/67 (43%), Gaps = 16/67 (23%)

Query: 38  AGGGGGGGRYYGGGSEG----GRAPKRLKTDNAGDQHGGGGGGGGGA------------G 81
           A GGGGGG  YGG   G    G         + G    GGGGGGGG+            G
Sbjct: 233 AYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWGGRSNSGPYRG 292

Query: 82  AAGGGGG 88
             GGGGG
Sbjct: 293 GYGGGGG 299



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 21/49 (42%), Positives = 26/49 (53%), Gaps = 12/49 (24%)

Query: 35  MAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAA 83
           M + GGGGGGG  +GG S            N+G   GG GGGGG  G++
Sbjct: 268 MKSGGGGGGGGSSWGGRS------------NSGPYRGGYGGGGGYGGSS 304



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 24/75 (32%), Positives = 29/75 (38%), Gaps = 24/75 (32%)

Query: 39  GGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGG----------------GGGAGA 82
           GGGGGG   YGGG  G        +   G  +G G GG                GGG G 
Sbjct: 225 GGGGGGYNAYGGGGGG--------SSYGGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGGG 276

Query: 83  AGGGGGGENYDDPHK 97
            G   GG +   P++
Sbjct: 277 GGSSWGGRSNSGPYR 291


>gi|109255251 loricrin [Homo sapiens]
          Length = 312

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 32/78 (41%), Positives = 37/78 (47%), Gaps = 8/78 (10%)

Query: 18 QRQQPDEQRRRSGAMVKMAAAGGGGGG------GRYYGGGSEGGRAPKRLKTDNAGDQHG 71
          Q++QP  Q       VK +  GGGGGG      G + GGGS GG +         G   G
Sbjct: 4  QKKQPTPQPPVD--CVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSG 61

Query: 72 GGGGGGGGAGAAGGGGGG 89
          GG GGG   G  GGG GG
Sbjct: 62 GGCGGGSSGGGGGGGIGG 79



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 28/67 (41%), Positives = 33/67 (49%), Gaps = 8/67 (11%)

Query: 29  SGAMVKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGG----GGGGAGAAG 84
           SG      ++GGGGGGG    GG  GG     +K    G   GGG G    GGGG+G   
Sbjct: 60  SGGGCGGGSSGGGGGGGIGGCGGGSGG----SVKYSGGGGSSGGGSGCFSSGGGGSGCFS 115

Query: 85  GGGGGEN 91
            GGGG +
Sbjct: 116 SGGGGSS 122



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 26/71 (36%), Positives = 32/71 (45%), Gaps = 18/71 (25%)

Query: 36  AAAGGGG------GGGRYYGGGSEGGRAPKRLKTDNA------------GDQHGGGGGGG 77
           ++ GGGG      GGG   GGGS GG     + +               G   GGGG GG
Sbjct: 178 SSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGG 237

Query: 78  GGAGAAGGGGG 88
            G  ++GGGGG
Sbjct: 238 SGCFSSGGGGG 248



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 25/62 (40%), Positives = 30/62 (48%), Gaps = 3/62 (4%)

Query: 38  AGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAA-GGGGGGENYDDPH 96
           + GGGGG    GGGS G            G   GGG  GGGG G++ GG G G+     H
Sbjct: 242 SSGGGGGSSGCGGGSSG--IGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKGVPICH 299

Query: 97  KT 98
           +T
Sbjct: 300 QT 301



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 28/75 (37%), Positives = 32/75 (42%), Gaps = 22/75 (29%)

Query: 29  SGAMVKMAAAGG-----------GGGGGRYY---GGGSEGGRAPKRLKTDNAGDQHGGGG 74
           SG  VK +  GG           GGGG   +   GGGS GG         +     GGGG
Sbjct: 84  SGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGG--------GSGCFSSGGGG 135

Query: 75  GGGGGAGAAGGGGGG 89
             GGG+G    GGGG
Sbjct: 136 SSGGGSGCFSSGGGG 150



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 25/64 (39%), Positives = 31/64 (48%), Gaps = 16/64 (25%)

Query: 37  AAGGGGGGGRY-----YGGGSEGGRAPKRLKTDNAGDQHGGGGGG------GGGAGAAGG 85
           ++GGGG  G+      YGG S GG +        +G    GGGGG      GGG+G  GG
Sbjct: 145 SSGGGGFSGQAVQCQSYGGVSSGGSSG-----GGSGCFSSGGGGGSVCGYSGGGSGCGGG 199

Query: 86  GGGG 89
             GG
Sbjct: 200 SSGG 203



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 25/61 (40%), Positives = 29/61 (47%), Gaps = 11/61 (18%)

Query: 38  AGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGG-----GGGGGGGAG----AAGGGGG 88
           +GGGG  G   GGGS GG     +     G   GG     GGGG  G G    ++GGGG 
Sbjct: 54  SGGGGYSGGGCGGGSSGGGGGGGI--GGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGS 111

Query: 89  G 89
           G
Sbjct: 112 G 112



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 18/54 (33%), Positives = 25/54 (46%)

Query: 36  AAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGG 89
           +  GG  GGG        GG + + ++  + G    GG  GGG    + GGGGG
Sbjct: 131 SGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGG 184



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 17/75 (22%)

Query: 48  YGGGSEGGRAPKRLKTDNAGDQHGGGGGGGG-----------------GAGAAGGGGGGE 90
           YGGGS GG         ++G   G  G GGG                 G G++GGGGGG 
Sbjct: 225 YGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGS 284

Query: 91  NYDDPHKTPASPVVH 105
           +          P+ H
Sbjct: 285 SVGGSGSGKGVPICH 299



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 30/87 (34%)

Query: 35  MAAAGGGG-------------------GGGRYYGGGSEGGRAPKRLKTDNAGD------- 68
           +++ G  G                   GGG   GGGS GG     + +            
Sbjct: 164 VSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQP 223

Query: 69  QHGGGGGGGGGAGAAG----GGGGGEN 91
            +GGG  GGGG+G +G    GGGGG +
Sbjct: 224 SYGGGSSGGGGSGGSGCFSSGGGGGSS 250


>gi|49574532 glycogen synthase kinase 3 alpha [Homo sapiens]
          Length = 483

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 27/74 (36%), Positives = 35/74 (47%), Gaps = 4/74 (5%)

Query: 26 RRRSGAMVKMAAAGGGGGGGRYYG----GGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAG 81
          R R+ +  +    GGGGGGG        GG+ GG+A         G    GGG GG G G
Sbjct: 16 RARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASVGAMGGGVGASSSGGGPGGSGGG 75

Query: 82 AAGGGGGGENYDDP 95
           +GG G G ++  P
Sbjct: 76 GSGGPGAGTSFPPP 89



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 22/48 (45%), Positives = 24/48 (50%)

Query: 43 GGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGGE 90
          GGG   GG    GRA      +  G   GGGGG GG A   GG GGG+
Sbjct: 3  GGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGK 50



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 20/51 (39%), Positives = 22/51 (43%), Gaps = 3/51 (5%)

Query: 38 AGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGG 88
          +GGG  GG   G G  G            G   GGGG GG  +G  G GGG
Sbjct: 2  SGGGPSGG---GPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGG 49


>gi|56699482 hypothetical protein LOC25940 [Homo sapiens]
          Length = 518

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 28/79 (35%), Positives = 34/79 (43%), Gaps = 4/79 (5%)

Query: 20  QQPDEQRRRSGAMVKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGG- 78
           + P  Q+R+ G   +    GGG GG  +   G  GG      +    G  HGG GGG G 
Sbjct: 318 EMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGN 377

Query: 79  ---GAGAAGGGGGGENYDD 94
              G    GG GGG  Y D
Sbjct: 378 KHQGGWTDGGSGGGGGYQD 396



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 23/54 (42%), Positives = 27/54 (50%), Gaps = 5/54 (9%)

Query: 39  GGGGGG----GRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGG 88
           GGG GG      Y G G +GG   +  +  + G  HG  GGG GG G  GG GG
Sbjct: 420 GGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGG-HHGDRGGGRGGRGGRGGRGG 472



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 23/51 (45%), Positives = 25/51 (49%), Gaps = 13/51 (25%)

Query: 39  GGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGG---GGGGGGAGAAGGG 86
           GG GG G Y  GG  GGR          G++H GG   GG GGG G   GG
Sbjct: 358 GGRGGRGGYDHGGRGGGR----------GNKHQGGWTDGGSGGGGGYQDGG 398



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 4/54 (7%)

Query: 40  GGGGGGRYYGGGSEGGRAPKRLKTD----NAGDQHGGGGGGGGGAGAAGGGGGG 89
           GGG G ++ GG ++GG        D    ++G Q GG  GG    G  GGG GG
Sbjct: 372 GGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGG 425



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 20/54 (37%), Positives = 22/54 (40%), Gaps = 8/54 (14%)

Query: 39  GGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGGENY 92
           G GGGGG   GG  + G  P        G  HGG   GG   G  GG     +Y
Sbjct: 387 GSGGGGGYQDGGYRDSGFQP--------GGYHGGHSSGGYQGGGYGGFQTSSSY 432



 Score = 30.8 bits (68), Expect = 3.6
 Identities = 21/51 (41%), Positives = 23/51 (45%), Gaps = 15/51 (29%)

Query: 40  GGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGGE 90
           GGG GGR  G G  GGRA              G GGG GG G+     GG+
Sbjct: 458 GGGRGGRG-GRGGRGGRA--------------GQGGGWGGRGSQNYHQGGQ 493



 Score = 29.6 bits (65), Expect = 8.1
 Identities = 22/59 (37%), Positives = 24/59 (40%), Gaps = 9/59 (15%)

Query: 38  AGGGGGG----GRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGGENY 92
           +G  GGG     RY  GG  G R   R          GG GG   G G   GG G +NY
Sbjct: 435 SGYQGGGYQQDNRYQDGGHHGDRGGGR----GGRGGRGGRGGR-AGQGGGWGGRGSQNY 488


>gi|4507741 twist [Homo sapiens]
          Length = 202

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 30/84 (35%), Positives = 39/84 (46%), Gaps = 9/84 (10%)

Query: 20  QQPDEQRRRSGAM------VKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGG 73
           ++PD Q+  SG            +AGGG G G   GGG  GG  P        G +  G 
Sbjct: 22  EEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGC 81

Query: 74  GGGGGGAGAAG---GGGGGENYDD 94
           GGGGG  G  G   GGG  ++Y++
Sbjct: 82  GGGGGAGGGGGSSSGGGSPQSYEE 105



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 20/58 (34%), Positives = 23/58 (39%), Gaps = 14/58 (24%)

Query: 51  GSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGGENYDDPHKTPASPVVHIRG 108
           G  GGR  +         +   GGG G G  A GG GGG+        P SP    RG
Sbjct: 32  GKRGGRKRR-------SSRRSAGGGAGPGGAAGGGVGGGDE-------PGSPAQGKRG 75


>gi|154091020 leucine-rich repeats and calponin homology (CH)
          domain containing 2 [Homo sapiens]
          Length = 765

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 30/58 (51%), Positives = 31/58 (53%), Gaps = 17/58 (29%)

Query: 35 MAAAGGGGG---GGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGG 89
          MAA+ GGGG   GG   GGGS GG               G  GGGGGGAG  GGGGGG
Sbjct: 1  MAASQGGGGNSGGGGCGGGGSSGG--------------CGTAGGGGGGAGGGGGGGGG 44


>gi|31542255 hypothetical protein LOC140706 [Homo sapiens]
          Length = 433

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 36/103 (34%), Positives = 46/103 (44%), Gaps = 13/103 (12%)

Query: 10  EKRRRRLEQRQQPD---EQRRRSGAMVKMAAAGGGGGGG--RYYGGGSEGGRAPKRLKTD 64
           EKRR    +R+      + R   G     A AGGGGGG   R   G    G   +R    
Sbjct: 185 EKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFS 244

Query: 65  NAGDQHGGGGGGGGGAGAAG--------GGGGGENYDDPHKTP 99
            + ++  GGGGGGGGAG  G        G GGG +++  H  P
Sbjct: 245 GSWERRHGGGGGGGGAGKPGGSWERRQAGSGGGGSWERRHPGP 287


>gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]
          Length = 331

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 29/64 (45%), Positives = 31/64 (48%), Gaps = 22/64 (34%)

Query: 28 RSGAMVKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGG 87
          RS   V+ A  GGGGGGG   GGG                   GGGGGG GG GA GG G
Sbjct: 51 RSSPAVRAAGGGGGGGGG---GGG-------------------GGGGGGVGGGGAGGGAG 88

Query: 88 GGEN 91
          GG +
Sbjct: 89 GGRS 92



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 21/46 (45%), Positives = 24/46 (52%)

Query: 44 GGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGG 89
          G +   G +E GR  +      A    GGGGGGGGG G  GG GGG
Sbjct: 36 GAKEPTGCTEAGRDDRSSPAVRAAGGGGGGGGGGGGGGGGGGVGGG 81



 Score = 30.8 bits (68), Expect = 3.6
 Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 3/47 (6%)

Query: 17 EQRQQPDEQRRRSGAMVKMAAAGGGGG---GGRYYGGGSEGGRAPKR 60
          + R  P  +    G        GGGGG   GG   GGG+ GGR+P R
Sbjct: 49 DDRSSPAVRAAGGGGGGGGGGGGGGGGGGVGGGGAGGGAGGGRSPVR 95


>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
           sapiens]
          Length = 419

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 32/79 (40%), Positives = 36/79 (45%), Gaps = 19/79 (24%)

Query: 29  SGAMVKMAAAGGGG----GGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAG 84
           S ++  MA AGG G    GGG + G G  GG           G   GGG GGGGG G  G
Sbjct: 122 SPSLALMAGAGGAGAAAGGGGAHDGPGGGGG--------PGGGGGPGGGPGGGGGGGPGG 173

Query: 85  GGG-------GGENYDDPH 96
           GGG       GG  +  PH
Sbjct: 174 GGGGPGGGLLGGSAHPHPH 192



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 32/76 (42%), Positives = 33/76 (43%), Gaps = 18/76 (23%)

Query: 29  SGAMVKMAAAGGGG-----GGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAA 83
           +GA    AAAGGGG     GGG   GGG   G  P             GGGGGGG  G  
Sbjct: 129 AGAGGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGP-------------GGGGGGGPGGGG 175

Query: 84  GGGGGGENYDDPHKTP 99
           GG GGG      H  P
Sbjct: 176 GGPGGGLLGGSAHPHP 191


>gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
           isoform b [Homo sapiens]
          Length = 373

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 36/106 (33%), Positives = 47/106 (44%), Gaps = 25/106 (23%)

Query: 30  GAMVKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGG-- 87
           GA    AA+ GG GG    G  S GG               GGGGGGGGG GAAG GG  
Sbjct: 201 GAAGSAAASAGGAGGAGGGGPASAGGG--------------GGGGGGGGGGGAAGAGGAL 246

Query: 88  ------GGENYDDPHKTPASPVVHIRGL---IDGVVEADLVEALQE 124
                 GG ++DD         + +R L   + GV + +++   Q+
Sbjct: 247 HPHHAAGGLHFDDRFSDEQLVTMSVRELNRQLRGVSKEEVIRLKQK 292



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 22/67 (32%), Positives = 24/67 (35%), Gaps = 13/67 (19%)

Query: 36  AAAGGGGGGGRYYG-------------GGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGA 82
           AAA   G G  Y+               G+ G           AG   GGG    GG G 
Sbjct: 170 AAAAQSGAGPHYHHHHHHAAGHHHHPTAGAPGAAGSAAASAGGAGGAGGGGPASAGGGGG 229

Query: 83  AGGGGGG 89
            GGGGGG
Sbjct: 230 GGGGGGG 236



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 28/94 (29%), Positives = 32/94 (34%), Gaps = 38/94 (40%)

Query: 34  KMAAAGGGGGGGRYYGGGSEGGRAPKRLKT--------------------DNAGDQH--- 70
           ++AAA G G G    G G E G A   +                        AG  H   
Sbjct: 137 QLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSGAGPHYHHHHHHAAGHHHHPT 196

Query: 71  ---------------GGGGGGGGGAGAAGGGGGG 89
                          G GG GGGG  +AGGGGGG
Sbjct: 197 AGAPGAAGSAAASAGGAGGAGGGGPASAGGGGGG 230


>gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
           isoform a [Homo sapiens]
          Length = 403

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 36/106 (33%), Positives = 47/106 (44%), Gaps = 25/106 (23%)

Query: 30  GAMVKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGG-- 87
           GA    AA+ GG GG    G  S GG               GGGGGGGGG GAAG GG  
Sbjct: 201 GAAGSAAASAGGAGGAGGGGPASAGGG--------------GGGGGGGGGGGAAGAGGAL 246

Query: 88  ------GGENYDDPHKTPASPVVHIRGL---IDGVVEADLVEALQE 124
                 GG ++DD         + +R L   + GV + +++   Q+
Sbjct: 247 HPHHAAGGLHFDDRFSDEQLVTMSVRELNRQLRGVSKEEVIRLKQK 292



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 22/67 (32%), Positives = 24/67 (35%), Gaps = 13/67 (19%)

Query: 36  AAAGGGGGGGRYYG-------------GGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGA 82
           AAA   G G  Y+               G+ G           AG   GGG    GG G 
Sbjct: 170 AAAAQSGAGPHYHHHHHHAAGHHHHPTAGAPGAAGSAAASAGGAGGAGGGGPASAGGGGG 229

Query: 83  AGGGGGG 89
            GGGGGG
Sbjct: 230 GGGGGGG 236



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 28/94 (29%), Positives = 32/94 (34%), Gaps = 38/94 (40%)

Query: 34  KMAAAGGGGGGGRYYGGGSEGGRAPKRLKT--------------------DNAGDQH--- 70
           ++AAA G G G    G G E G A   +                        AG  H   
Sbjct: 137 QLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSGAGPHYHHHHHHAAGHHHHPT 196

Query: 71  ---------------GGGGGGGGGAGAAGGGGGG 89
                          G GG GGGG  +AGGGGGG
Sbjct: 197 AGAPGAAGSAAASAGGAGGAGGGGPASAGGGGGG 230


>gi|42544153 leukocyte receptor tyrosine kinase isoform 1 precursor
           [Homo sapiens]
          Length = 864

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 37/100 (37%), Positives = 43/100 (43%), Gaps = 16/100 (16%)

Query: 8   RAEKRRRRLEQRQQPDEQRRRSGAMVKMAAAGGGGG---------GGRYYGGGSEGGRAP 58
           R +    +LE R +      R GA      AGGGGG          GR    G+EGG+  
Sbjct: 247 RTQASPEKLENRSEAPGSGGRGGA------AGGGGGWTSRAPSPQAGRSLQEGAEGGQGC 300

Query: 59  KRLKTDNAGDQHGGGGGGGGGAGAAGGGGGGENYDDPHKT 98
                   G    GG GGGGGA  AGGGGGG    D  +T
Sbjct: 301 SEAWA-TLGWAAAGGFGGGGGACTAGGGGGGYRGGDASET 339



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 27/66 (40%), Positives = 36/66 (54%), Gaps = 11/66 (16%)

Query: 26  RRRSGAMVKMAAAGGGGGGGRYYGGGSEGGR---APKRLKTDNAGDQHGGGGGGGGGAGA 82
           R R+G +  +  A GGGG  R Y    + GR   +P++L  +N  +  G GG G    GA
Sbjct: 219 RVRAGELEPLLVAAGGGG--RAYLRPRDRGRTQASPEKL--ENRSEAPGSGGRG----GA 270

Query: 83  AGGGGG 88
           AGGGGG
Sbjct: 271 AGGGGG 276



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 28/84 (33%), Positives = 33/84 (39%), Gaps = 14/84 (16%)

Query: 13  RRRLEQRQQPDEQRRRSGAMVKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGG 72
           R R   +  P++   RS       A G GG GG   GGG    RAP      +  +   G
Sbjct: 243 RDRGRTQASPEKLENRS------EAPGSGGRGGAAGGGGGWTSRAPSPQAGRSLQEGAEG 296

Query: 73  GGG--------GGGGAGAAGGGGG 88
           G G        G   AG  GGGGG
Sbjct: 297 GQGCSEAWATLGWAAAGGFGGGGG 320



 Score = 30.8 bits (68), Expect = 3.6
 Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 2/54 (3%)

Query: 14  RRLEQRQQPDEQRRRSGAMVKMAAAGG--GGGGGRYYGGGSEGGRAPKRLKTDN 65
           R L++  +  +    + A +  AAAGG  GGGG    GGG  G R     +TDN
Sbjct: 288 RSLQEGAEGGQGCSEAWATLGWAAAGGFGGGGGACTAGGGGGGYRGGDASETDN 341


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.136    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,525,119
Number of Sequences: 37866
Number of extensions: 1921784
Number of successful extensions: 33874
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 515
Number of HSP's successfully gapped in prelim test: 571
Number of HSP's that attempted gapping in prelim test: 14737
Number of HSP's gapped (non-prelim): 8751
length of query: 589
length of database: 18,247,518
effective HSP length: 108
effective length of query: 481
effective length of database: 14,157,990
effective search space: 6809993190
effective search space used: 6809993190
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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