Search of human proteins with 50658079

Search of human proteins with 50658079

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo
sapiens]
         (1281 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo ...  2555   0.0  
gi|217330594 tubulin tyrosine ligase-like family, member 4 [Homo...   300   4e-81
gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo ...   231   4e-60
gi|75677580 tubulin tyrosine ligase-like family, member 13 [Homo...   227   5e-59
gi|94536793 tubulin tyrosine ligase-like family, member 7 [Homo ...   216   1e-55
gi|195963418 tubulin tyrosine ligase-like family, member 6 isofo...   213   1e-54
gi|11068135 tubulin tyrosine ligase-like family, member 1 [Homo ...   190   7e-48
gi|212720861 tubulin tyrosine ligase-like family, member 11 a [H...   161   3e-39
gi|56606131 tubulin tyrosine ligase-like family, member 9 [Homo ...   145   2e-34
gi|89363028 tubulin tyrosine ligase-like family, member 11 b [Ho...   133   1e-30
gi|109134340 tubulin tyrosine ligase-like family, member 3 [Homo...   110   9e-24
gi|122937293 tubulin tyrosine ligase-like family, member 8 [Homo...   107   7e-23
gi|194239681 tubulin tyrosine ligase-like family, member 10 isof...    98   4e-20
gi|24308516 tubulin tyrosine ligase [Homo sapiens]                     87   8e-17
gi|195963416 tubulin tyrosine ligase-like family, member 6 isofo...    80   1e-14
gi|194239678 tubulin tyrosine ligase-like family, member 10 isof...    75   4e-13
gi|11056036 tubulin tyrosine ligase-like family, member 12 [Homo...    56   2e-07
gi|83367077 mucin 16 [Homo sapiens]                                    45   4e-04
gi|189217904 RPGRIP1-like isoform b [Homo sapiens]                     43   0.002
gi|118442834 RPGRIP1-like isoform a [Homo sapiens]                     43   0.002
gi|19913406 DNA topoisomerase II, alpha isozyme [Homo sapiens]         42   0.003
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    42   0.003
gi|151301154 mucin 6, gastric [Homo sapiens]                           42   0.004
gi|188497758 ubiquitin associated protein 2-like isoform a [Homo...    42   0.004
gi|188497756 ubiquitin associated protein 2-like isoform b [Homo...    42   0.004
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi...    41   0.008
gi|33946327 nucleoporin 214kDa [Homo sapiens]                          41   0.008
gi|153085395 histone deacetylase 4 [Homo sapiens]                      41   0.008
gi|167736355 mucin 4 isoform a [Homo sapiens]                          40   0.019
gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]        40   0.019

>gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo
            sapiens]
          Length = 1281

 Score = 2555 bits (6622), Expect = 0.0
 Identities = 1281/1281 (100%), Positives = 1281/1281 (100%)

Query: 1    MPIVMARDLEETASSSEDEEVISQEDHPCIMWTGGCRRIPVLVFHADAILTKDNNIRVIG 60
            MPIVMARDLEETASSSEDEEVISQEDHPCIMWTGGCRRIPVLVFHADAILTKDNNIRVIG
Sbjct: 1    MPIVMARDLEETASSSEDEEVISQEDHPCIMWTGGCRRIPVLVFHADAILTKDNNIRVIG 60

Query: 61   ERYHLSYKIVRTDSRLVRSILTAHGFHEVHPSSTDYNLMWTGSHLKPFLLRTLSEAQKVN 120
            ERYHLSYKIVRTDSRLVRSILTAHGFHEVHPSSTDYNLMWTGSHLKPFLLRTLSEAQKVN
Sbjct: 61   ERYHLSYKIVRTDSRLVRSILTAHGFHEVHPSSTDYNLMWTGSHLKPFLLRTLSEAQKVN 120

Query: 121  HFPRSYELTRKDRLYKNIIRMQHTHGFKAFHILPQTFLLPAEYAEFCNSYSKDRGPWIVK 180
            HFPRSYELTRKDRLYKNIIRMQHTHGFKAFHILPQTFLLPAEYAEFCNSYSKDRGPWIVK
Sbjct: 121  HFPRSYELTRKDRLYKNIIRMQHTHGFKAFHILPQTFLLPAEYAEFCNSYSKDRGPWIVK 180

Query: 181  PVASSRGRGVYLINNPNQISLEENILVSRYINNPLLIDDFKFDVRLYVLVTSYDPLVIYL 240
            PVASSRGRGVYLINNPNQISLEENILVSRYINNPLLIDDFKFDVRLYVLVTSYDPLVIYL
Sbjct: 181  PVASSRGRGVYLINNPNQISLEENILVSRYINNPLLIDDFKFDVRLYVLVTSYDPLVIYL 240

Query: 241  YEEGLARFATVRYDQGAKNIRNQFMHLTNYSVNKKSGDYVSCDDPEVEDYGNKWSMSAML 300
            YEEGLARFATVRYDQGAKNIRNQFMHLTNYSVNKKSGDYVSCDDPEVEDYGNKWSMSAML
Sbjct: 241  YEEGLARFATVRYDQGAKNIRNQFMHLTNYSVNKKSGDYVSCDDPEVEDYGNKWSMSAML 300

Query: 301  RYLKQEGRDTTALMAHVEDLIIKTIISAELAIATACKTFVPHRSSCFELYGFDVLIDSTL 360
            RYLKQEGRDTTALMAHVEDLIIKTIISAELAIATACKTFVPHRSSCFELYGFDVLIDSTL
Sbjct: 301  RYLKQEGRDTTALMAHVEDLIIKTIISAELAIATACKTFVPHRSSCFELYGFDVLIDSTL 360

Query: 361  KPWLLEVNLSPSLACDAPLDLKIKASMISDMFTVVGFVCQDPAQRASTRPIYPTFESSRR 420
            KPWLLEVNLSPSLACDAPLDLKIKASMISDMFTVVGFVCQDPAQRASTRPIYPTFESSRR
Sbjct: 361  KPWLLEVNLSPSLACDAPLDLKIKASMISDMFTVVGFVCQDPAQRASTRPIYPTFESSRR 420

Query: 421  NPFQKPQRCRPLSASDAEMKNLVGSAREKGPGKLGGSVLGLSMEEIKVLRRVKEENDRRG 480
            NPFQKPQRCRPLSASDAEMKNLVGSAREKGPGKLGGSVLGLSMEEIKVLRRVKEENDRRG
Sbjct: 421  NPFQKPQRCRPLSASDAEMKNLVGSAREKGPGKLGGSVLGLSMEEIKVLRRVKEENDRRG 480

Query: 481  GFIRIFPTSETWEIYGSYLEHKTSMNYMLATRLFQDRMTADGAPELKIESLNSKAKLHAA 540
            GFIRIFPTSETWEIYGSYLEHKTSMNYMLATRLFQDRMTADGAPELKIESLNSKAKLHAA
Sbjct: 481  GFIRIFPTSETWEIYGSYLEHKTSMNYMLATRLFQDRMTADGAPELKIESLNSKAKLHAA 540

Query: 541  LYERKLLSLEVRKRRRRSSRLRAMRPKYPVITQPAEMNVKTETESEEEEEVALDNEDEEQ 600
            LYERKLLSLEVRKRRRRSSRLRAMRPKYPVITQPAEMNVKTETESEEEEEVALDNEDEEQ
Sbjct: 541  LYERKLLSLEVRKRRRRSSRLRAMRPKYPVITQPAEMNVKTETESEEEEEVALDNEDEEQ 600

Query: 601  EASQEESAGFLRENQAKYTPSLTALVENTPKENSMKVREWNNKGGHCCKLETQELEPKFN 660
            EASQEESAGFLRENQAKYTPSLTALVENTPKENSMKVREWNNKGGHCCKLETQELEPKFN
Sbjct: 601  EASQEESAGFLRENQAKYTPSLTALVENTPKENSMKVREWNNKGGHCCKLETQELEPKFN 660

Query: 661  LMQILQDNGNLSKMQARIAFSAYLQHVQIRLMKDSGGQTFSASWAAKEDEQMELVVRFLK 720
            LMQILQDNGNLSKMQARIAFSAYLQHVQIRLMKDSGGQTFSASWAAKEDEQMELVVRFLK
Sbjct: 661  LMQILQDNGNLSKMQARIAFSAYLQHVQIRLMKDSGGQTFSASWAAKEDEQMELVVRFLK 720

Query: 721  RASNNLQHSLRMVLPSRRLALLERRRILAHQLGDFIIVYNKETEQMAEKKSKKKVEEEEE 780
            RASNNLQHSLRMVLPSRRLALLERRRILAHQLGDFIIVYNKETEQMAEKKSKKKVEEEEE
Sbjct: 721  RASNNLQHSLRMVLPSRRLALLERRRILAHQLGDFIIVYNKETEQMAEKKSKKKVEEEEE 780

Query: 781  DGVNMENFQEFIRQASEAELEEVLTFYTQKNKSASVFLGTHSKISKNNNNYSDSGAKGDH 840
            DGVNMENFQEFIRQASEAELEEVLTFYTQKNKSASVFLGTHSKISKNNNNYSDSGAKGDH
Sbjct: 781  DGVNMENFQEFIRQASEAELEEVLTFYTQKNKSASVFLGTHSKISKNNNNYSDSGAKGDH 840

Query: 841  PETIMEEVKIKPPKQQQTTEIHSDKLSRFTTSAEKEAKLVYSNSSSGPTATLQKIPNTHL 900
            PETIMEEVKIKPPKQQQTTEIHSDKLSRFTTSAEKEAKLVYSNSSSGPTATLQKIPNTHL
Sbjct: 841  PETIMEEVKIKPPKQQQTTEIHSDKLSRFTTSAEKEAKLVYSNSSSGPTATLQKIPNTHL 900

Query: 901  SSVTTSDLSPGPCHHSSLSQIPSAIPSMPHQPTILLNTVSASASPCLHPGAQNIPSPTGL 960
            SSVTTSDLSPGPCHHSSLSQIPSAIPSMPHQPTILLNTVSASASPCLHPGAQNIPSPTGL
Sbjct: 901  SSVTTSDLSPGPCHHSSLSQIPSAIPSMPHQPTILLNTVSASASPCLHPGAQNIPSPTGL 960

Query: 961  PRCRSGSHTIGPFSSFQSAAHIYSQKLSRPSSAKAGSCYLNKHHSGIAKTQKEGEDASLY 1020
            PRCRSGSHTIGPFSSFQSAAHIYSQKLSRPSSAKAGSCYLNKHHSGIAKTQKEGEDASLY
Sbjct: 961  PRCRSGSHTIGPFSSFQSAAHIYSQKLSRPSSAKAGSCYLNKHHSGIAKTQKEGEDASLY 1020

Query: 1021 SKRYNQSMVTAELQRLAEKQAARQYSPSSHINLLTQQVTNLNLATGIINRSSASAPPTLR 1080
            SKRYNQSMVTAELQRLAEKQAARQYSPSSHINLLTQQVTNLNLATGIINRSSASAPPTLR
Sbjct: 1021 SKRYNQSMVTAELQRLAEKQAARQYSPSSHINLLTQQVTNLNLATGIINRSSASAPPTLR 1080

Query: 1081 PIISPSGPTWSTQSDPQAPENHSSSPGSRSLQTGGFAWEGEVENNVYSQATGVVPQHKYH 1140
            PIISPSGPTWSTQSDPQAPENHSSSPGSRSLQTGGFAWEGEVENNVYSQATGVVPQHKYH
Sbjct: 1081 PIISPSGPTWSTQSDPQAPENHSSSPGSRSLQTGGFAWEGEVENNVYSQATGVVPQHKYH 1140

Query: 1141 PTAGSYQLQFALQQLEQQKLQSRQLLDQSRARHQAIFGSQTLPNSNLWTMNNGAGCRISS 1200
            PTAGSYQLQFALQQLEQQKLQSRQLLDQSRARHQAIFGSQTLPNSNLWTMNNGAGCRISS
Sbjct: 1141 PTAGSYQLQFALQQLEQQKLQSRQLLDQSRARHQAIFGSQTLPNSNLWTMNNGAGCRISS 1200

Query: 1201 ATASGQKPTTLPQKVVPPPSSCASLVPKPPPNHEQVLRRATSQKASKGSSAEGQLNGLQS 1260
            ATASGQKPTTLPQKVVPPPSSCASLVPKPPPNHEQVLRRATSQKASKGSSAEGQLNGLQS
Sbjct: 1201 ATASGQKPTTLPQKVVPPPSSCASLVPKPPPNHEQVLRRATSQKASKGSSAEGQLNGLQS 1260

Query: 1261 SLNPAAFVPITSSTDPAHTKI 1281
            SLNPAAFVPITSSTDPAHTKI
Sbjct: 1261 SLNPAAFVPITSSTDPAHTKI 1281


>gi|217330594 tubulin tyrosine ligase-like family, member 4 [Homo
            sapiens]
          Length = 1199

 Score =  300 bits (769), Expect = 4e-81
 Identities = 169/444 (38%), Positives = 264/444 (59%), Gaps = 11/444 (2%)

Query: 51   TKDNNIRVIG--ERYHLSYKIVRTDSRLVRSILTAHGFHEVHPSSTDYNLMWTGSHLKPF 108
            T+D  +  +   +R  L +K+      +V+  +    F ++   + D+   W G H+K  
Sbjct: 591  TRDERVEKLPWEQRKLLRWKMSTVTPNIVKQTIGRSHF-KISKRNDDWLGCW-GHHMKSP 648

Query: 109  LLRTLSEAQKVNHFPRSYELTRKDRLYKNIIRMQHTHGFKAFHILPQTFLLPAEYAEFCN 168
              R++ E QK+NHFP S+++ RKDRL++N+ RMQ   G K F   PQ+F+LP +      
Sbjct: 649  SFRSIREHQKLNHFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFILPQDAKLLRK 708

Query: 169  SY-SKDRGPWIVKPVASSRGRGVYLINNPNQISLEENILVSRYINNPLLIDDFKFDVRLY 227
            ++ S  R  WIVKP AS+RG G+ +I+  +Q+     +LV RY++ P LI   KFD+R+Y
Sbjct: 709  AWESSSRQKWIVKPPASARGIGIQVIHKWSQLPKRRPLLVQRYLHKPYLISGSKFDLRIY 768

Query: 228  VLVTSYDPLVIYLYEEGLARFATVRYDQGAKNIRNQFMHLTNYSVNKKSGDYVSCDDPEV 287
            V VTSYDPL IYL+ +GL RFA+ +Y    K++ N+FMHLTNYSVNKK+ +Y +  D E+
Sbjct: 769  VYVTSYDPLRIYLFSDGLVRFASCKYSPSMKSLGNKFMHLTNYSVNKKNAEYQANAD-EM 827

Query: 288  EDYGNKWSMSAMLRYLKQEGRDTTALMAHVEDLIIKTIISAELAIATACKTFVPHRSSCF 347
               G+KW++ A+  YL Q+G ++ A+   ++D+++KTIIS+E  + +  K +V    SC 
Sbjct: 828  ACQGHKWALKALWNYLSQKGVNSDAIWEKIKDVVVKTIISSEPYVTSLLKMYVRRPYSCH 887

Query: 348  ELYGFDVLIDSTLKPWLLEVNLSPSLACDAPLDLKIKASMISDMFTVVGFVCQDPAQRAS 407
            EL+GFD+++D  LKPW+LEVN+SPSL   +PLD+ IK  MI D+  + GFV  +     S
Sbjct: 888  ELFGFDIMLDENLKPWVLEVNISPSLHSSSPLDISIKGQMIRDLLNLAGFVLPNAEDIIS 947

Query: 408  TRPIYPTFESSRRNPFQKPQRCR--PLSASDAEMKNLVGSAREKGPGKLGGSVLG-LSME 464
            +        S+   P     +CR  P   +  +MK      ++        SVL  L+ +
Sbjct: 948  SPS--SCSSSTTSLPTSPGDKCRMAPEHVTAQKMKKAYYLTQKIPDQDFYASVLDVLTPD 1005

Query: 465  EIKVLRRVKEENDRRGGFIRIFPT 488
            ++++L  +++E  RRG F RIFP+
Sbjct: 1006 DVRILVEMEDEFSRRGQFERIFPS 1029


>gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo
           sapiens]
          Length = 592

 Score =  231 bits (588), Expect = 4e-60
 Identities = 125/341 (36%), Positives = 195/341 (57%), Gaps = 22/341 (6%)

Query: 65  LSYKIVRTDSRLVRSILTAHG---FHEVHPSSTDYNLMWTGSHLKPFLLRTLSEAQKVNH 121
           L +++  T   +V+S+L   G   F +   ++ D+NL W  S  +     ++   Q++NH
Sbjct: 87  LVFRVDETTPAVVQSVLLERGWNKFDKQEQNAEDWNLYWRTSSFRMTEHNSVKPWQQLNH 146

Query: 122 FPRSYELTRKDRLYKNIIRMQHTHGFKAFHILPQTFLLPAEYAEFCNSYSKDR------- 174
            P + +LTRKD L K++  M+  +G   +  +P TF++P +Y +F   Y ++R       
Sbjct: 147 HPGTTKLTRKDCLAKHLKHMRRMYGTSLYQFIPLTFVMPNDYTKFVAEYFQERQMLGTKH 206

Query: 175 GPWIVKPVASSRGRGVYLINNPNQISLEENILVSRYINNPLLIDDFKFDVRLYVLVTSYD 234
             WI KP   SRGRG+ + ++      ++  +V +YI+NPLLI  +K D+R+YV VT + 
Sbjct: 207 SYWICKPAELSRGRGILIFSDFKDFIFDDMYIVQKYISNPLLIGRYKCDLRIYVCVTGFK 266

Query: 235 PLVIYLYEEGLARFATVRYDQGAKNIRNQFMHLTNYSVNKKSGDYVSCDDPEVEDYGNKW 294
           PL IY+Y+EGL RFAT ++D    N++N + HLTN S+NK    Y      EV  +G KW
Sbjct: 267 PLTIYVYQEGLVRFATEKFD--LSNLQNNYAHLTNSSINKSGASYEKI--KEVIGHGCKW 322

Query: 295 SMSAMLRYLKQEGRDTTALMAHVEDLIIKTIISAELAIATACKTFVPHRSSCFELYGFDV 354
           ++S    YL+    D   L   +  ++I TI    LAIA +    VP  ++CFEL+GFD+
Sbjct: 323 TLSRFFSYLRSWDVDDLLLWKKIHRMVILTI----LAIAPS----VPFAANCFELFGFDI 374

Query: 355 LIDSTLKPWLLEVNLSPSLACDAPLDLKIKASMISDMFTVV 395
           LID  LKPWLLEVN SP+L  D   D+ +K  ++ D+  ++
Sbjct: 375 LIDDNLKPWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDLI 415


>gi|75677580 tubulin tyrosine ligase-like family, member 13 [Homo
           sapiens]
          Length = 459

 Score =  227 bits (579), Expect = 5e-59
 Identities = 134/343 (39%), Positives = 200/343 (58%), Gaps = 16/343 (4%)

Query: 61  ERYHLSYKIVRTDSRLVRSILTAHGFHEVHPSSTDYNLMWTGSHLKPFLLRTLSEAQKVN 120
           +R  L+  +       VR      G  EV     ++ L WT   +    +  +   QK+N
Sbjct: 84  KRRSLAINLTNCKYESVRRAAQMCGLKEVGEDE-EWTLYWTDCAVSLERVMDMKRFQKIN 142

Query: 121 HFPRSYELTRKDRLYKNIIRMQHTHGFKAFHILPQTFLLPAEYAEFCNSYSKDRGP--WI 178
           HFP   E+ RKD L +N+ RM   +  + ++I P+T+ LPA+Y +F  SY + R    +I
Sbjct: 143 HFPGMTEICRKDLLARNLNRMYKLYPSE-YNIFPRTWCLPADYGDF-QSYGRQRKARTYI 200

Query: 179 VKPVASSRGRGVYLINNPNQISLEENILVSRYINNPLLIDDFKFDVRLYVLVTSYDPLVI 238
            KP +  +GRG+++  NP +I   E+++  +YI+ PLLID FKFD+R+YVL+TS DPL I
Sbjct: 201 CKPDSGCQGRGIFITRNPREIKPGEHMICQQYISKPLLIDGFKFDMRVYVLITSCDPLRI 260

Query: 239 YLYEEGLARFATVRY-DQGAKNIRNQFMHLTNYSVNKKSGDYVSCDDPEVEDYGNKWSMS 297
           + YEEGLARFAT  Y +    N+ N  MHLTNY++NK + ++V   D  V   G+K  +S
Sbjct: 261 FTYEEGLARFATTPYMEPSHNNLDNVCMHLTNYAINKHNENFVR--DGAV---GSKRKLS 315

Query: 298 AMLRYLKQEGRDTTALMAHVEDLIIKTIISAELAIATACKTFVPH-----RSSCFELYGF 352
            +  +L++   +   L   +ED+IIKTIISA   +    +T  P        +CFE+ GF
Sbjct: 316 TLNIWLQEHSYNPGELWGDIEDIIIKTIISAHSVLRHNYRTCFPQYLNGGTCACFEILGF 375

Query: 353 DVLIDSTLKPWLLEVNLSPSLACDAPLDLKIKASMISDMFTVV 395
           D+L+D  LKPWLLEVN SPS   D+ LD ++K +++ D  T+V
Sbjct: 376 DILLDHKLKPWLLEVNHSPSFTTDSCLDQEVKDALLCDAMTLV 418


>gi|94536793 tubulin tyrosine ligase-like family, member 7 [Homo
           sapiens]
          Length = 887

 Score =  216 bits (549), Expect = 1e-55
 Identities = 157/581 (27%), Positives = 275/581 (47%), Gaps = 39/581 (6%)

Query: 51  TKDNNIRVIGERYHLSYKIVRTDSRLVRSILTAHGFHEVHPSSTDYNLMWTGSHLKPFLL 110
           T    +R   ++  ++  +  T   +VR ++   GF +        NL+W  S ++   +
Sbjct: 27  TMKRKVRKKKKKGTITANVAGTKFEIVRLVIDEMGFMKTPDEDETSNLIWCDSAVQQEKI 86

Query: 111 RTLSEAQKVNHFPRSYELTRKDRLYKNIIRMQHTHGFKAFHILPQTFLLPAEYAEFCNSY 170
             L   Q++NHFP   E+ RKD L +N+ +M  +     +  +P+T++ PAEY +F N Y
Sbjct: 87  SELQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPLD-YTFVPRTWIFPAEYTQFQN-Y 144

Query: 171 SKD------RGPWIVKPVASSRGRGVYLINNPNQISLEENILVSRYINNPLLIDDFKFDV 224
            K+      +  +IVKP   + G G+ LI N +++  +++++V  YI  P L++ +KFD+
Sbjct: 145 VKELKKKRKQKTFIVKPANGAMGHGISLIRNGDKLPSQDHLIVQEYIEKPFLMEGYKFDL 204

Query: 225 RLYVLVTSYDPLVIYLYEEGLARFATVRY-DQGAKNIRNQFMHLTNYSVNKKSGDYVSCD 283
           R+Y+LVTS DPL I+LY +GL R  T +Y      N+   +MHLTNYSVNK +  +   +
Sbjct: 205 RIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNEHF---E 261

Query: 284 DPEVEDYGNKWSMSAMLRYLKQEGRDTTALMAHVEDLIIKTIISAELAIATACKTFVP-- 341
             E E+ G+K S+     +L+    D     + + +L++KT+I AE  +  A +   P  
Sbjct: 262 RDETENKGSKRSIKWFTEFLQANQHDVAKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQ 321

Query: 342 ---HRSSCFELYGFDVLIDSTLKPWLLEVNLSPSLACDAPLDLKIKASMISDMFTVVGFV 398
                S CFE+ GFD+L+D  LKPWLLE+N +PS   D  +D  +K  ++ +   ++   
Sbjct: 322 PPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKRGVLLNALKLLNIR 381

Query: 399 CQDPAQRASTRPIYPTFESSRRNPFQKP-QRCRPLSASDAEMKNLVGSAREKGPGKLGGS 457
             D  +  + +      E+ RR   Q   +R  P S+   + ++ +   +E+   +L   
Sbjct: 382 TSDKRRNLAKQKA----EAQRRLYGQNSIKRLLPGSSDWEQQRHQLERRKEELKERLA-- 435

Query: 458 VLGLSMEEIKVLRRVKEENDRRGGFIRIFPTSETWEIYGSYLEHKTSMNYMLATRLFQDR 517
                 +  K + R + EN   G + RI+P  +        L  K      +A + F   
Sbjct: 436 ------QVRKQISREEHENRHMGNYRRIYPPED------KALLEKYENLLAVAFQTFLSG 483

Query: 518 MTADGAPELKIESLNSKAKLHAALYERKLLSLEVRKRRRRSSRLRAMRPKYPVITQPAEM 577
             A    EL       K +    L E+    ++  K   ++++ R  +P    + +  E+
Sbjct: 484 RAASFQRELNNPLKRMKEEDILDLLEQ--CEIDDEKLMGKTTKTRGPKPLCS-MPESTEI 540

Query: 578 NVKTETESEEEEEVALDNEDEEQEASQEESAGFLRENQAKY 618
             + +  S +    +  +  E  E  +EE     RE Q  Y
Sbjct: 541 MKRPKYCSSDSSYDSSSSSSESDENEKEEYQNKKREKQVTY 581


>gi|195963418 tubulin tyrosine ligase-like family, member 6 isoform
           1 [Homo sapiens]
          Length = 891

 Score =  213 bits (541), Expect = 1e-54
 Identities = 124/325 (38%), Positives = 184/325 (56%), Gaps = 14/325 (4%)

Query: 77  VRSILTAHGFHEVHPSSTDYNLMWTGSHLKPFLLRTLSEAQKVNHFPRSYELTRKDRLYK 136
           VR     +GF E      D+ L WT   +    +  +   QK+NHFP   E+ RKD L +
Sbjct: 121 VRRAAQQYGFRE-GGEDDDWTLYWTDYSVSLERVMEMKSYQKINHFPGMSEICRKDLLAR 179

Query: 137 NIIRMQHTHGFKAFHILPQTFLLPAEYAEFCNSYSKDRG--PWIVKPVASSRGRGVYLIN 194
           N+ RM      K F   P+T+ LPA++ +   +YS+ R    +I KP +  +G+G+++  
Sbjct: 180 NMSRMLKMFP-KDFRFFPRTWCLPADWGDL-QTYSRSRKNKTYICKPDSGCQGKGIFITR 237

Query: 195 NPNQISLEENILVSRYINNPLLIDDFKFDVRLYVLVTSYDPLVIYLYEEGLARFATVRYD 254
              +I   E+++   YI+ P +ID FKFD+R+YVLVTS DPL I++Y EGLARFAT  Y 
Sbjct: 238 TVKEIKPGEDMICQLYISKPFIIDGFKFDLRIYVLVTSCDPLRIFVYNEGLARFATTSYS 297

Query: 255 QG-AKNIRNQFMHLTNYSVNKKSGDYVSCDDPEVEDYGNKWSMSAMLRYLKQEGRDTTAL 313
           +    N+ +  MHLTNYS+NK S ++           G+K  +S    YL+    +   +
Sbjct: 298 RPCTDNLDDICMHLTNYSINKHSSNF-----SRDAHSGSKRKLSTFSAYLEDHSYNVEQI 352

Query: 314 MAHVEDLIIKTIISAELAIATACKTFVPH---RSSCFELYGFDVLIDSTLKPWLLEVNLS 370
              +ED+IIKT+ISA   I     T  P+    S+CFE+ GFD+L+D  LKPWLLEVN S
Sbjct: 353 WRDIEDVIIKTLISAHPIIRHNYHTCFPNHTLNSACFEILGFDILLDHKLKPWLLEVNHS 412

Query: 371 PSLACDAPLDLKIKASMISDMFTVV 395
           PS + D+ LD ++K  ++ D   ++
Sbjct: 413 PSFSTDSRLDKEVKDGLLYDTLVLI 437


>gi|11068135 tubulin tyrosine ligase-like family, member 1 [Homo
           sapiens]
          Length = 423

 Score =  190 bits (483), Expect = 7e-48
 Identities = 113/314 (35%), Positives = 167/314 (53%), Gaps = 47/314 (14%)

Query: 113 LSEAQKVNHFPRSYELTRKDRLYKNIIRMQ--------------HTHGFKAFHILPQTFL 158
           LS+ Q VNHFP  YELTRKD + KNI R +                  +     +P T++
Sbjct: 56  LSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYM 115

Query: 159 LPAEYAEFCNSYSKD-RGPWIVKPVASSRGRGVYLINNPNQI---------------SLE 202
           LPA+Y  F   + K     WI+KP   ++G+G++LIN  +QI               S +
Sbjct: 116 LPADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNK 175

Query: 203 ENILVSRYINNPLLIDDFKFDVRLYVLVTSYDPLVIYLYEEGLARFATVRYDQGAKNIRN 262
           E  ++S YINNPLLI   KFD+RLYVLV++Y PL  Y+Y+ G  RF TV+Y      + N
Sbjct: 176 EAYVISLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDN 235

Query: 263 QFMHLTNYSVNKKSGDYVSCDDPEVEDYGNKWSMSAMLRYLKQ-EGRDTTA-LMAHVEDL 320
            F+HLTN ++ K   DY          +G KW++S +  YL+   G++ T+ L   +  +
Sbjct: 236 MFVHLTNVAIQKHGEDYNHI-------HGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWI 288

Query: 321 IIKTIISAELAIATACKTFVPHRSSCFELYGFDVLIDSTLKPWLLEVNLSPSLACDAPLD 380
           I++++         A    + +   CFE YG+D++ID  LKPWL+EVN SPSL      D
Sbjct: 289 IVQSL--------KAVAPVMNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTAND 340

Query: 381 LKIKASMISDMFTV 394
             +K ++I+D   +
Sbjct: 341 RILKYNLINDTLNI 354


>gi|212720861 tubulin tyrosine ligase-like family, member 11 a [Homo
           sapiens]
          Length = 800

 Score =  161 bits (408), Expect = 3e-39
 Identities = 100/272 (36%), Positives = 155/272 (56%), Gaps = 20/272 (7%)

Query: 118 KVNHFPRSYELTRKDRLYKNIIRMQHTHGFKAFHILPQTFLLPAEYAEFCNSYS--KDRG 175
           +VN FP   E+ RK  L + +  MQ+    + ++  P++++LP E+  F       KD  
Sbjct: 271 QVNKFPGMTEMVRKITLSRAVRTMQNLFP-EEYNFYPRSWILPDEFQLFVAQVQMVKDDD 329

Query: 176 P-----WIVKPVASSRGRGVYLINNPNQISLEENI-----LVSRYINNPLLIDDFKFDVR 225
           P     +IVKP    +G G+YLI +P+ I L   +     +V  YI  PLLID  KFD+R
Sbjct: 330 PSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRPAVVQEYICKPLLIDKLKFDIR 389

Query: 226 LYVLVTSYDPLVIYLYEEGLARFATVRYDQGA-KNIRNQFMHLTNYSVNKKSGDYVSCDD 284
           LYVL+ S DPL IY+ ++GL+RF T  Y +   KN+   FMHLTNYS+N  SG+++  D 
Sbjct: 390 LYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTNYSLNIHSGNFIHSDS 449

Query: 285 PEVEDYGNKWSMSAMLRYLKQEGRDTTALMAHVEDLIIKTIISAELAIATACKTFVP--- 341
                 G+K + S++L  L  +G D   + + +  ++IKT+I+    +    ++ +P   
Sbjct: 450 AST---GSKRTFSSILCRLSSKGVDIKKVWSDIISVVIKTVIALTPELKVFYQSDIPTGR 506

Query: 342 HRSSCFELYGFDVLIDSTLKPWLLEVNLSPSL 373
              +CF++ GFD+L+   LKP LLEVN +PS+
Sbjct: 507 PGPTCFQILGFDILLMKNLKPILLEVNANPSM 538


>gi|56606131 tubulin tyrosine ligase-like family, member 9 [Homo
           sapiens]
          Length = 439

 Score =  145 bits (366), Expect = 2e-34
 Identities = 104/309 (33%), Positives = 148/309 (47%), Gaps = 58/309 (18%)

Query: 113 LSEAQKVNHFPRSYELTRKDRLYKNIIRMQHTHGFKAFHI-------LPQTFLLPAEYAE 165
           + E  +++HF   YELTRK+ + KN+ R +     +A  +        P+TF +P EY  
Sbjct: 92  MDEHVRISHFRNHYELTRKNYMVKNLKRFRKQLEREAGKLEAAKCDFFPKTFEMPCEYHL 151

Query: 166 FCNSYSKDRG-PWIVKPVASSRGRGVYLINNPNQIS----------------LEENILVS 208
           F   + K+ G  WI+KPVA S+G+G++L      I                   EN +  
Sbjct: 152 FVEEFRKNPGITWIMKPVARSQGKGIFLFRRLKDIVDWRKDTRSSDDQKDDIPVENYVAQ 211

Query: 209 RYINNPLLIDDFKFDVRLYVLVTSYDPLVIYLYEEGLARFATVRYDQGAKNIRNQFMHLT 268
           RYI NP LI   KFD+R+YVLV S               FA      G    R Q +HLT
Sbjct: 212 RYIENPYLIGGRKFDLRVYVLVMSV--------------FAECLLWSGH---RRQDVHLT 254

Query: 269 NYSVNKKSGDYVSCDDPEVEDYGNKWSMSAMLRYL--KQEGRDTTALMAHVEDLIIKTII 326
           N +V K S DY     P+    G KW++    +YL  K        L   ++++ +K++ 
Sbjct: 255 NVAVQKTSPDY----HPKK---GCKWTLQRFRQYLASKHGPEAVETLFRDIDNIFVKSLQ 307

Query: 327 SAELAIATACKTFVPHRSSCFELYGFDVLIDSTLKPWLLEVNLSPSLACDAPLDLKIKAS 386
           S +  I +           CFELYG+D+LID  LKPWLLEVN SPSL   +  D ++K  
Sbjct: 308 SVQKVIISD--------KHCFELYGYDILIDQDLKPWLLEVNASPSLTASSQEDYELKTC 359

Query: 387 MISDMFTVV 395
           ++ D   VV
Sbjct: 360 LLEDTLHVV 368


>gi|89363028 tubulin tyrosine ligase-like family, member 11 b [Homo
           sapiens]
          Length = 538

 Score =  133 bits (335), Expect = 1e-30
 Identities = 83/223 (37%), Positives = 127/223 (56%), Gaps = 17/223 (7%)

Query: 118 KVNHFPRSYELTRKDRLYKNIIRMQHTHGFKAFHILPQTFLLPAEYAEFCNSYS--KDRG 175
           +VN FP   E+ RK  L + +  MQ+    + ++  P++++LP E+  F       KD  
Sbjct: 271 QVNKFPGMTEMVRKITLSRAVRTMQNLFP-EEYNFYPRSWILPDEFQLFVAQVQMVKDDD 329

Query: 176 P-----WIVKPVASSRGRGVYLINNPNQISLEENI-----LVSRYINNPLLIDDFKFDVR 225
           P     +IVKP    +G G+YLI +P+ I L   +     +V  YI  PLLID  KFD+R
Sbjct: 330 PSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRPAVVQEYICKPLLIDKLKFDIR 389

Query: 226 LYVLVTSYDPLVIYLYEEGLARFATVRYDQGA-KNIRNQFMHLTNYSVNKKSGDYVSCDD 284
           LYVL+ S DPL IY+ ++GL+RF T  Y +   KN+   FMHLTNYS+N  SG+++  D 
Sbjct: 390 LYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTNYSLNIHSGNFIHSDS 449

Query: 285 PEVEDYGNKWSMSAMLRYLKQEGRDTTALMAHVEDLIIKTIIS 327
                 G+K + S++L  L  +G D   + + +  ++IKT+I+
Sbjct: 450 AST---GSKRTFSSILCRLSSKGVDIKKVWSDIISVVIKTVIA 489


>gi|109134340 tubulin tyrosine ligase-like family, member 3 [Homo
           sapiens]
          Length = 772

 Score =  110 bits (275), Expect = 9e-24
 Identities = 76/236 (32%), Positives = 119/236 (50%), Gaps = 26/236 (11%)

Query: 173 DRGPWIVKPVASSRGRGVY----------LINNPNQISLEENILVSRYINNPLLIDDFKF 222
           DR  WIVKP A SRGRG+           L+N    +  +   +V +YI  PLLI   KF
Sbjct: 276 DRNIWIVKPGAKSRGRGIMCMDHLEEMLKLVNGNPVVMKDGKWVVQKYIERPLLIFGTKF 335

Query: 223 DVRLYVLVTSYDPLVIYLYEEGLARFATVRYDQGAKNIRNQFMHLTNYSVNKKSGDYVSC 282
           D+R + LVT ++PL ++ Y +   RF+T  +    KN+ N  +HL N S+ K   +  SC
Sbjct: 336 DLRQWFLVTDWNPLTVWFYRDSYIRFSTQPF--SLKNLDNS-VHLCNNSIQKHLEN--SC 390

Query: 283 DDPEVEDYGNKWSMSAMLRYLKQEGRD---TTALMAHVEDLIIKTIISAELAIATACKTF 339
               +    N WS      +L++ G     +T ++  ++D +I        A+ T+  T 
Sbjct: 391 HRHPLLPPDNMWSSQRFQAHLQEMGAPNAWSTIIVPGMKDAVIH-------ALQTSQDT- 442

Query: 340 VPHRSSCFELYGFDVLIDSTLKPWLLEVNLSPSLACDAPLDLKIKASMISDMFTVV 395
           V  R + FELYG D +     +PWL+E+N SP++A    +  ++ A + +D   VV
Sbjct: 443 VQCRKASFELYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADTLRVV 498


>gi|122937293 tubulin tyrosine ligase-like family, member 8 [Homo
           sapiens]
          Length = 834

 Score =  107 bits (267), Expect = 7e-23
 Identities = 74/235 (31%), Positives = 120/235 (51%), Gaps = 24/235 (10%)

Query: 174 RGPWIVKPVASSRGRG--------------VYLINNPNQISLEENILVSRYINNPLLIDD 219
           R  WI+KP A SRGRG              + L    + +S +   +V +YI  PLLI D
Sbjct: 328 RNIWIIKPAAKSRGRGESPDIVCMDRVEEILELAAADHPLSRDNKWVVQKYIETPLLICD 387

Query: 220 FKFDVRLYVLVTSYDPLVIYLYEEGLARFATVRYDQGAKNIRNQFMHLTNYSVNKKSGDY 279
            KFD+R + LVT ++PL I+ Y+E   RF+T R+   + +  +  +HL N +V K   + 
Sbjct: 388 TKFDIRQWFLVTDWNPLTIWFYKESYLRFSTQRF---SLDKLDSAIHLCNNAVQKYLKND 444

Query: 280 VSCDDPEVEDYGNKWSMSAMLRYLKQEGRDTTALMAHVEDLIIKTIISAELAIATACKTF 339
           V    P +  + N W+ +    YL+++GR   A+   V    +K  I+  + +A   +  
Sbjct: 445 VG-RSPLLPAH-NMWTSTRFQEYLQRQGRG--AVWGSVIYPSMKKAIAHAMKVA---QDH 497

Query: 340 VPHRSSCFELYGFDVLIDSTLKPWLLEVNLSPSLACDAPLDLKIKASMISDMFTV 394
           V  R + FELYG D ++    +PWL+E+N SP++    P+  ++ A +  D   V
Sbjct: 498 VEPRKNSFELYGADFVLGRDFRPWLIEINSSPTMHPSTPVTAQLCAQVQEDTIKV 552


>gi|194239681 tubulin tyrosine ligase-like family, member 10 isoform
           1 [Homo sapiens]
          Length = 673

 Score = 98.2 bits (243), Expect = 4e-20
 Identities = 70/222 (31%), Positives = 104/222 (46%), Gaps = 38/222 (17%)

Query: 177 WIVKPVASSRGRGVYLINNPNQI--------SLEENIL-------------VSRYINNPL 215
           WI KP AS++G+G++L+ N  ++        S+E++ +             V RYI NPL
Sbjct: 310 WICKPTASNQGKGIFLLRNQEEVAALQAKTRSMEDDPIHHKTPFRGPQARVVQRYIQNPL 369

Query: 216 LIDDFKFDVRLYVLVTSYDPLVIYLYEEGLARFATVRYDQGAKNIRNQFMHLTNYSVNKK 275
           L+D  KFDVR Y+L+    P +I+ +  G AR     YD  + ++     HLTN  + KK
Sbjct: 370 LVDGRKFDVRSYLLIACTTPYMIF-FGHGYARLTLSLYDPHSSDLGG---HLTNQFMQKK 425

Query: 276 SGDYVSCDDPEVEDYGNKWSMSAMLRYLKQEGRDTTALMAHVEDLIIKTIISAELAIATA 335
           S  Y+   +  V      WSM  + RY+         L    +D +  T+      I   
Sbjct: 426 SPLYMLLKEHTV------WSMEHLNRYISDTFWKARGL---AKDWVFTTLKKRMQQIMAH 476

Query: 336 CKTFVPHRSSC----FELYGFDVLIDSTLKPWLLEVNLSPSL 373
           C      +  C    F+L G D LID   K WLLE+N +P+L
Sbjct: 477 CFLAAKPKLDCKLGYFDLIGCDFLIDDNFKVWLLEMNSNPAL 518


>gi|24308516 tubulin tyrosine ligase [Homo sapiens]
          Length = 377

 Score = 87.4 bits (215), Expect = 8e-17
 Identities = 66/227 (29%), Positives = 122/227 (53%), Gaps = 34/227 (14%)

Query: 177 WIVKPVASSRGRGVYLINNPNQI-----SLEENILVSRYINNPLLIDDF--KFDVRLYVL 229
           WI K  A ++G G+ + +  +++     +  +  ++ +Y+ +PLL++    KFD+R +VL
Sbjct: 147 WIAKSSAGAKGEGILISSEASELLDFIDNQGQVHVIQKYLEHPLLLEPGHRKFDIRSWVL 206

Query: 230 VT-SYDPLVIYLYEEGLARFATVRYDQGAKNIRNQFMHLTNYSVNKK-SGDYVSCDDPEV 287
           V   Y+   IYLY EG+ R A+  Y     N +++  HLTN+ + K+ S +Y   ++   
Sbjct: 207 VDHQYN---IYLYREGVLRTASEPYH--VDNFQDKTCHLTNHCIQKEYSKNYGKYEE--- 258

Query: 288 EDYGNKWSMSAMLRYLKQEGRDT--TALMAHVEDLIIKTIISAELAIATACKTFVPHRSS 345
              GN+       +YL      T  ++++  ++ +I   ++S E AI+T     +P++S 
Sbjct: 259 ---GNEMFFKEFNQYLTSALNITLESSILLQIKHIIRNCLLSVEPAISTK---HLPYQS- 311

Query: 346 CFELYGFDVLIDSTLKPWLLEVNLSPSLA-------CDAPLDLKIKA 385
            F+L+GFD ++D  LK WL+EVN +P+ A       C   +D+ I +
Sbjct: 312 -FQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDIAISS 357


>gi|195963416 tubulin tyrosine ligase-like family, member 6 isoform
           2 [Homo sapiens]
          Length = 584

 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 41/103 (39%), Positives = 61/103 (59%), Gaps = 3/103 (2%)

Query: 296 MSAMLRYLKQEGRDTTALMAHVEDLIIKTIISAELAIATACKTFVPHR---SSCFELYGF 352
           +S    YL+    +   +   +ED+IIKT+ISA   I     T  P+    S+CFE+ GF
Sbjct: 28  LSTFSAYLEDHSYNVEQIWRDIEDVIIKTLISAHPIIRHNYHTCFPNHTLNSACFEILGF 87

Query: 353 DVLIDSTLKPWLLEVNLSPSLACDAPLDLKIKASMISDMFTVV 395
           D+L+D  LKPWLLEVN SPS + D+ LD ++K  ++ D   ++
Sbjct: 88  DILLDHKLKPWLLEVNHSPSFSTDSRLDKEVKDGLLYDTLVLI 130


>gi|194239678 tubulin tyrosine ligase-like family, member 10 isoform
           2 [Homo sapiens]
          Length = 404

 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 49/148 (33%), Positives = 75/148 (50%), Gaps = 31/148 (20%)

Query: 177 WIVKPVASSRGRGVYLINNPNQI--------SLEENIL-------------VSRYINNPL 215
           WI KP AS++G+G++L+ N  ++        S+E++ +             V RYI NPL
Sbjct: 237 WICKPTASNQGKGIFLLRNQEEVAALQAKTRSMEDDPIHHKTPFRGPQARVVQRYIQNPL 296

Query: 216 LIDDFKFDVRLYVLVTSYDPLVIYLYEEGLARFATVRYDQGAKNIRNQFMHLTNYSVNKK 275
           L+D  KFDVR Y+L+    P +I+ +  G AR     YD  + ++     HLTN  + KK
Sbjct: 297 LVDGRKFDVRSYLLIACTTPYMIF-FGHGYARLTLSLYDPHSSDLGG---HLTNQFMQKK 352

Query: 276 SGDYVSCDDPEVEDYGNKWSMSAMLRYL 303
           S  Y+   +  V      WSM  + RY+
Sbjct: 353 SPLYMLLKEHTV------WSMEHLNRYI 374


>gi|11056036 tubulin tyrosine ligase-like family, member 12 [Homo
           sapiens]
          Length = 644

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 58/196 (29%), Positives = 93/196 (47%), Gaps = 22/196 (11%)

Query: 70  VRTDSRLVRSILTAHGFHEVHPSSTDYNLMWTGSHLKPFLLRTLSEAQK---VNHFPRSY 126
           V TD + V S LT H    +  S  D ++++  SH K +  R LS+ +    +N FP   
Sbjct: 307 VYTDVQQVASSLT-HPRFTLTQSEADADILFNFSHFKDY--RKLSQERPGVLLNQFPCEN 363

Query: 127 ELTRKDRLYKNIIRMQHTHGFKAFHILPQTFLLPAEYAEFCNSYSK-----DRGPWIVKP 181
            LT KD L  +I R     G +    LP+TF L  E  +F + + +     +   WI KP
Sbjct: 364 LLTVKDCL-ASIAR--RAGGPEGPPWLPRTFNLRTELPQFVSYFQQRERWGEDNHWICKP 420

Query: 182 VASSRGRGVYLINNPNQISLEENI---LVSRYINNPLL-----IDDFKFDVRLYVLVTSY 233
              +R    ++  + + I         +VS+YI +P+L     +   KFD+R  VL+ S 
Sbjct: 421 WNLARSLDTHVTKSLHSIIRHRESTPKVVSKYIESPVLFLREDVGKVKFDIRYIVLLRSV 480

Query: 234 DPLVIYLYEEGLARFA 249
            PL +++Y+    RF+
Sbjct: 481 RPLRLFVYDVFWLRFS 496


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 64/258 (24%), Positives = 98/258 (37%), Gaps = 33/258 (12%)

Query: 882  SNSSSGPTATLQKIPNTHLSSVTTS-DLSPGPCHHSSLSQIPSAIPSMPHQPTILLNTVS 940
            S S   P  +L  IP++  S+ ++S   SP     + +     AI +   Q T    T  
Sbjct: 2904 SASLPTPGQSLNTIPDSDASTASSSLSKSPEKNPRARMMTSTKAISASSFQSTGFTETPE 2963

Query: 941  ASASPCLHPGAQNIP-SPTGLPRCRSGSHTIGPFSSFQSA------AHIYSQKLSRPSSA 993
             SASP +      +P S TG PR  S S +    S   SA      A   +   S   +A
Sbjct: 2964 GSASPSMAGHEPRVPTSGTGDPRYASESMSYPDPSKASSAMTSTSLASKLTTLFSTGQAA 3023

Query: 994  KAGSCY------LNKHHSGIAKTQKEGEDASLY--SKRYNQSMVTAELQRLAEKQAARQY 1045
            ++GS          K  S ++ T       SL+       Q  +   LQ      +A   
Sbjct: 3024 RSGSSSSPISLSTEKETSFLSPTASTSRKTSLFLGPSMARQPNILVHLQT-----SALTL 3078

Query: 1046 SPSSHINLLTQQVTNLNLATGIINRSSASA------------PPTLRPIISPSGPTWSTQ 1093
            SP+S +N+  ++   L  +  I      +A            P +L P+ SP+ PT   +
Sbjct: 3079 SPTSTLNMSQEEPPELTSSQTIAEEEGTTAETQTLTFTPSETPTSLLPVSSPTEPTARRK 3138

Query: 1094 SDPQAPENHSSSPGSRSL 1111
            S P+   +  S P   SL
Sbjct: 3139 SSPETWASSISVPAKTSL 3156



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 90/463 (19%), Positives = 168/463 (36%), Gaps = 74/463 (15%)

Query: 876  EAKLVYSNSSSGPTATLQKI--PNTHLSSVTTSDLSPGPCHHSSLSQIPSAIP---SMPH 930
            E  L  S +S+G    L+ +  P+  +  +T   ++  P H SS S      P   +   
Sbjct: 2683 ETTLTMSETSNGDALVLKTVSNPDRSIPGITIQGVTESPLHPSSTSPSKIVAPRNTTYEG 2742

Query: 931  QPTILLNTVSASASPCL--HPGAQN------IPSPTGLPRCRSGSHTIGPFSSFQSAAHI 982
              T+ L+T+ A  +  L     ++N      + S  GL R      T G           
Sbjct: 2743 SITVALSTLPAGTTGSLVFSQSSENSETTALVDSSAGLERASVMPLTTG----------- 2791

Query: 983  YSQKLSRPSSAKAGSCYLN--KHHSGIAKTQKEGEDASLYSKRYNQSMVTAELQ------ 1034
             SQ ++     ++GS +    K  S +  T   GE  ++     N+   T          
Sbjct: 2792 -SQGMASSGGIRSGSTHSTGTKTFSSLPLTMNPGEVTAMSEITTNRLTATQSTAPKGIPV 2850

Query: 1035 --RLAEKQAARQYSPSSHINLLTQQVTNLNLATGI--------------INRSSASAPPT 1078
                AE       S SS  +     +T      GI              ++  SAS P  
Sbjct: 2851 KPTSAESGLLTPVSASSSPSKAFASLTTAPPTWGIPQSTLTFEFSEVPSLDTKSASLPTP 2910

Query: 1079 LRPI--ISPSGPTWSTQSDPQAPENHSSS---PGSRSLQTGGFAWEGEVENNVYSQATGV 1133
             + +  I  S  + ++ S  ++PE +  +     ++++    F   G  E    S +  +
Sbjct: 2911 GQSLNTIPDSDASTASSSLSKSPEKNPRARMMTSTKAISASSFQSTGFTETPEGSASPSM 2970

Query: 1134 VPQHKYHPTAGSYQLQFALQQL---EQQKLQSRQLLDQSRARHQAIFGS----QTLPNSN 1186
                   PT+G+   ++A + +   +  K  S        ++   +F +    ++  +S+
Sbjct: 2971 AGHEPRVPTSGTGDPRYASESMSYPDPSKASSAMTSTSLASKLTTLFSTGQAARSGSSSS 3030

Query: 1187 LWTMNNGAGCRISSATASGQKPTTL---------PQKVVPPPSSCASLVPKPPPNHEQV- 1236
              +++        S TAS  + T+L         P  +V   +S  +L P    N  Q  
Sbjct: 3031 PISLSTEKETSFLSPTASTSRKTSLFLGPSMARQPNILVHLQTSALTLSPTSTLNMSQEE 3090

Query: 1237 ---LRRATSQKASKGSSAEGQLNGLQSSLNPAAFVPITSSTDP 1276
               L  + +    +G++AE Q      S  P + +P++S T+P
Sbjct: 3091 PPELTSSQTIAEEEGTTAETQTLTFTPSETPTSLLPVSSPTEP 3133



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 53/210 (25%), Positives = 81/210 (38%), Gaps = 22/210 (10%)

Query: 901  SSVTTSDLSPGPCHHSSLSQIPSAIPSMPHQPTILL--------------NTVSASASPC 946
            SSV++S  SP     S  S +P +I S PH  T LL              +    S+ P 
Sbjct: 8559 SSVSSSLSSPAMTSTSFFSTLPESISSSPHPVTALLTLGPVKTTDMLRTSSEPETSSPPN 8618

Query: 947  LHPGAQNIPSPTGLPRCRSGSHTIGPFSSFQSAAHIYSQKLSRPSSAKAGSCYLNKHHSG 1006
            L   +  I + + + + R   H             IY  K   PSS  A      K  S 
Sbjct: 8619 LSSTSAEILATSEVTKDREKIHPSSNTPVVNVGTVIY--KHLSPSSVLA-DLVTTKPTSP 8675

Query: 1007 IAKTQKEGE-DASLYSKRYNQSMVTAELQRLAEKQAARQYSPSSHINLLTQQVTNLN-LA 1064
            +A T   G    S  +  + ++M+T     L      R+ S S   +  T++  +L+ + 
Sbjct: 8676 MATTSTLGNTSVSTSTPAFPETMMTQPTSSLT--SGLREISTSQETSSATERSASLSGMP 8733

Query: 1065 TGIINRSSASAPPTLRPIISPSGPTWSTQS 1094
            TG   + S +   +L    +P GP  ST S
Sbjct: 8734 TGATTKVSRTEALSLGRTSTP-GPAQSTIS 8762



 Score = 31.6 bits (70), Expect = 5.1
 Identities = 34/126 (26%), Positives = 53/126 (42%), Gaps = 19/126 (15%)

Query: 863   SDKLSRFTTSAEKEAKLVYSNSSSGPTATLQKIPNTHLSSVTTSDLSPGPCHHSSLSQIP 922
             S  +SR T+S        +S+SS   T  +   P T  SS   + +SPG       SQI 
Sbjct: 11698 STPVSRTTSS--------FSHSSPDATPVMATSPRTEASSAVLTTISPG-APEMVTSQIT 11748

Query: 923   SA-------IPSMPHQPTILLNTVSASASPCLHPGAQNIPSPTGLPRC--RSGSHTIGPF 973
             S+       +P++ H P +   T   S  P     ++  P+ T  P+    + S TI P 
Sbjct: 11749 SSGAATSTTVPTLTHSPGMPETTALLSTHPRTET-SKTFPASTVFPQVSETTASLTIRPG 11807

Query: 974   SSFQSA 979
             +   +A
Sbjct: 11808 AETSTA 11813



 Score = 30.8 bits (68), Expect = 8.7
 Identities = 64/314 (20%), Positives = 104/314 (33%), Gaps = 53/314 (16%)

Query: 808  TQKNKSASVFLGTHSKISKN--------NNNYSDSGAKGDHPETIMEEVKIKPPKQQQTT 859
            T    S + + GTHS +++           + S  G     P ++ E      P      
Sbjct: 5877 TLDTSSTASWEGTHSPVTQRFPHSEETTTMSRSTKGVSWQSPPSVEETSSPSSPVPLPAI 5936

Query: 860  EIHSDKLSRFTTSAEKEAKLVYSNSSSGPTATLQKIPNTHLSSVTTSDLSPGPCHHSSLS 919
              HS   S  + S+   A  V S  +SG   T+  + +TH   VT+S             
Sbjct: 5937 TSHSSLYSAVSGSSPTSALPVTSLLTSGRRKTIDML-DTHSELVTSS------------- 5982

Query: 920  QIPSAIPSMPHQPTILLNTVSASASPCLHPGAQNIPSPTGLPRCRSGSHTIGPFSSFQSA 979
                 +PS       +L + +++ +  +H       +  G         T        S+
Sbjct: 5983 -----LPSASSFSGEILTSEASTNTETIHFSENTAETNMG---------TTNSMHKLHSS 6028

Query: 980  AHIYSQKLSRPSSAKAGSCYLNKHHSGIAKTQKEGEDASLYSKRYNQSMVTAELQRLAEK 1039
              I+SQ          GS         I  T   G   +    R + S +T EL+   E 
Sbjct: 6029 VSIHSQPSGHTPPKVTGSMM----EDAIVSTSTPGSPETKNVDRDSTSPLTPELK---ED 6081

Query: 1040 QAARQYSPSSHINLLTQQVTNLNLATGIINRS---------SASAPPTLRPIISPSGPTW 1090
              A   + ++  N +   V+ L+ AT +              ASA  T  P ISP   + 
Sbjct: 6082 STALVMNSTTESNTVFSSVS-LDAATEVSRAEVTYYDPTFMPASAQSTKSPDISPEASSS 6140

Query: 1091 STQSDPQAPENHSS 1104
             + S P     H +
Sbjct: 6141 HSNSPPLTISTHKT 6154


>gi|189217904 RPGRIP1-like isoform b [Homo sapiens]
          Length = 1235

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 56/247 (22%), Positives = 110/247 (44%), Gaps = 31/247 (12%)

Query: 611 LRENQAKYTPSLTALVENTPKENSMKVREWNNKGGHCCKLETQELEPKFNLMQILQDNGN 670
           L+E Q     S  AL+ N  + N M+++E   K   CC LE Q    KF+  +I +    
Sbjct: 292 LQEKQRTLRISHDALMANGDELN-MQLKEQRLK---CCSLEKQLHSMKFSERRIEELQDR 347

Query: 671 LSKMQARIAFSAYLQHVQIRLMKDSGGQTFSASWAAKEDEQMELVVRFLKRASNNLQHSL 730
           ++ ++            +  L+K++  + + ++++A  +EQ +L  + LK     L+ +L
Sbjct: 348 INDLEK-----------ERELLKENYDKLYDSAFSAAHEEQWKLKEQQLKVQIAQLETAL 396

Query: 731 RMVLPSRRLAL------LERRRILAHQLGDFIIVYNKETEQMAEKKSKKKVEEEEEDGVN 784
           +  L  +   L       ++   L  +  +  + Y ++ +Q+ E K + K+  +E D +N
Sbjct: 397 KSDLTDKTEILDRLKTERDQNEKLVQENRELQLQYLEQKQQLDELKKRIKLYNQEND-IN 455

Query: 785 MENFQEFIRQASEAELEEVLTFYTQKNKSASVFLGTHSKISKNNNNYSDSGAKGDHPETI 844
            +   E +    +A+ E       QKN   S  +   S+I+K+    S    +  H ET+
Sbjct: 456 ADELSEAL-LLIKAQKE-------QKNGDLSFLVKVDSEINKDLER-SMRELQATHAETV 506

Query: 845 MEEVKIK 851
            E  K +
Sbjct: 507 QELEKTR 513


>gi|118442834 RPGRIP1-like isoform a [Homo sapiens]
          Length = 1315

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 56/247 (22%), Positives = 110/247 (44%), Gaps = 31/247 (12%)

Query: 611 LRENQAKYTPSLTALVENTPKENSMKVREWNNKGGHCCKLETQELEPKFNLMQILQDNGN 670
           L+E Q     S  AL+ N  + N M+++E   K   CC LE Q    KF+  +I +    
Sbjct: 292 LQEKQRTLRISHDALMANGDELN-MQLKEQRLK---CCSLEKQLHSMKFSERRIEELQDR 347

Query: 671 LSKMQARIAFSAYLQHVQIRLMKDSGGQTFSASWAAKEDEQMELVVRFLKRASNNLQHSL 730
           ++ ++            +  L+K++  + + ++++A  +EQ +L  + LK     L+ +L
Sbjct: 348 INDLEK-----------ERELLKENYDKLYDSAFSAAHEEQWKLKEQQLKVQIAQLETAL 396

Query: 731 RMVLPSRRLAL------LERRRILAHQLGDFIIVYNKETEQMAEKKSKKKVEEEEEDGVN 784
           +  L  +   L       ++   L  +  +  + Y ++ +Q+ E K + K+  +E D +N
Sbjct: 397 KSDLTDKTEILDRLKTERDQNEKLVQENRELQLQYLEQKQQLDELKKRIKLYNQEND-IN 455

Query: 785 MENFQEFIRQASEAELEEVLTFYTQKNKSASVFLGTHSKISKNNNNYSDSGAKGDHPETI 844
            +   E +    +A+ E       QKN   S  +   S+I+K+    S    +  H ET+
Sbjct: 456 ADELSEAL-LLIKAQKE-------QKNGDLSFLVKVDSEINKDLER-SMRELQATHAETV 506

Query: 845 MEEVKIK 851
            E  K +
Sbjct: 507 QELEKTR 513


>gi|19913406 DNA topoisomerase II, alpha isozyme [Homo sapiens]
          Length = 1531

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 56/229 (24%), Positives = 90/229 (39%), Gaps = 39/229 (17%)

Query: 762  ETEQMAEKKSKKKVEEE------EEDGVNMENFQEFIRQASEAELEEVLTFYTQKNKSAS 815
            E +  AEKK+KKK++ E      +EDGV +E  ++ + +  + E          K K  +
Sbjct: 1226 EMKAEAEKKNKKKIKNENTEGSPQEDGVELEGLKQRLEKKQKRE-------PGTKTKKQT 1278

Query: 816  VFLGTHSKISKNNNNYSDSGAKGDHPETIME------EVKIKPPKQQQTTEIHSDK-LSR 868
                   K  K  N +SDS +     E+  +      E +    K + T ++ SD+  S 
Sbjct: 1279 TLAFKPIKKGKKRNPWSDSESDRSSDESNFDVPPRETEPRRAATKTKFTMDLDSDEDFSD 1338

Query: 869  FTTSAEKEAKLVYSNSSSGPTATLQKIPNTHL--SSVTTSDL-------------SPGPC 913
            F    + E   V S++S   T T  K+ N  L       SDL             SP   
Sbjct: 1339 FDEKTDDE-DFVPSDASPPKTKTSPKLSNKELKPQKSVVSDLEADDVKGSVPLSSSPPAT 1397

Query: 914  HHSSLSQIPSAIPSMPHQPTILLNTVSASASPCLHPGAQNIPSPTGLPR 962
            H    ++I + +P    +   +  T + S S     GA+   +P G  R
Sbjct: 1398 HFPDETEITNPVPK---KNVTVKKTAAKSQSSTSTTGAKKRAAPKGTKR 1443


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 61/254 (24%), Positives = 92/254 (36%), Gaps = 41/254 (16%)

Query: 1000 LNKHHSGIAKTQKEGEDASLYSKRYNQSMVTAELQRLAEKQAARQYSPSSHINLLTQQVT 1059
            + K    + K QKE  +     +   Q     + Q+  +  A    SPS    LLT+   
Sbjct: 3574 IQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPG 3633

Query: 1060 NLNLATGIINRSSASAPP-------TLRP-----IISPSGPTWSTQSDPQAPENHSSSPG 1107
             L    G+        PP        L P        P GP  +T    Q  + HS   G
Sbjct: 3634 QLLPGHGL---QPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAG 3690

Query: 1108 SRSLQTGGFAWEGEVENNVYSQATGVVPQHKYHPTAGSYQLQFALQQLEQQKLQSRQLLD 1167
            S +  +GGF + G +        + ++ + +        QL   LQQ +QQ+ Q + LL 
Sbjct: 3691 SLAGPSGGF-FPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLG 3749

Query: 1168 QSRARHQAIFGSQTLPNSNLWTMNNGAGCRISSATASGQKPTTLPQKVVPPPSSCASLV- 1226
            Q   + Q                  G G  + +  A G K    PQ ++PP S    LV 
Sbjct: 3750 QVAIQQQ---------------QQQGPG--VQTNQALGPK----PQGLMPPSSHQGLLVQ 3788

Query: 1227 ---PKPPPNHEQVL 1237
               P+PP   + +L
Sbjct: 3789 QLSPQPPQGPQGML 3802


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 42.0 bits (97), Expect = 0.004
 Identities = 49/218 (22%), Positives = 81/218 (37%), Gaps = 46/218 (21%)

Query: 820  THSKISKNNNNYSDSGAKGDHPET---IMEEVKIKPPKQQQTTEIHSDKLSRFTTSAEKE 876
            T S  S+ ++++S + A      +   + +    +PP    TT++     +    S   +
Sbjct: 2067 TTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQ 2126

Query: 877  AKLVYSNSSSGPTATLQKIPNTHLSSV-------TTSDLSPGPCH--------HSSLSQI 921
                +S S S P+     +P++H S         T+S     P H        HSSLS  
Sbjct: 2127 LSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTH 2186

Query: 922  P-----SAIPSMPHQPT----------------------ILLNTVSASASPCLHPGAQNI 954
            P     SA P  P  P                       + ++TV+ S +P  H  +  I
Sbjct: 2187 PTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTI 2246

Query: 955  PSPTGLPRCRSGSHTIGPFSSFQSAAHIYSQKLSRPSS 992
              P+  PR  + +HT   FSS  + +   S     P+S
Sbjct: 2247 AFPS-TPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTS 2283


>gi|188497758 ubiquitin associated protein 2-like isoform a [Homo
            sapiens]
          Length = 1087

 Score = 42.0 bits (97), Expect = 0.004
 Identities = 94/452 (20%), Positives = 161/452 (35%), Gaps = 71/452 (15%)

Query: 821  HSKISKNNNNYSDSGAKGDHPETIMEEVKIKPPKQQQTTEIHSD--KLSRFTTSAEKEAK 878
            HS+      +  D G+    P  +  ++K         + +HS   K   FT S+     
Sbjct: 379  HSQSGSTTTSSWDMGSTTQSPSLVQYDLK-----NPSDSAVHSPFTKRQAFTPSSTMMEV 433

Query: 879  LVYSNSSSGPTATLQKIP-NTHLSSVTTS--DLSPGPCHHSS------------------ 917
             +   S +  T+T    P ++ L S +TS   +SPG   + S                  
Sbjct: 434  FLQEKSPAVATSTAAPPPPSSPLPSKSTSAPQMSPGSSDNQSSSPQPAQQKLKQQKKKAS 493

Query: 918  -LSQIPSAIPSMPHQPTILLNTVSASASPCLHPGAQNIPSPTGLPRCRSGSHTIGPFSSF 976
              S+IP+    MP    I    +   A   L  G++ + S        S S +  P S +
Sbjct: 494  LTSKIPALAVEMPGSADISGLNLQFGA---LQFGSEPVLSDYESTPTTSASSSQAPSSLY 550

Query: 977  QSAAHIYSQKLSRPSSAKAGSCYLNKHHSGIAKTQKEGEDASLYSKRYNQSM-VTAELQR 1035
             S A   S  +S   S ++G  Y +        T +      LY +R  Q+    + +  
Sbjct: 551  TSTASESSSTISSNQSQESG--YQSGPIQSTTYTSQNNAQGPLYEQRSTQTRRYPSSISS 608

Query: 1036 LAEKQAARQYSPSSHINLLTQQVT-NLNLATGIINRSSASAPPTLRPIISPSGPTWSTQS 1094
              +K   +  +  S +     Q T ++  ATG   +S + +  ++ P+      T S  S
Sbjct: 609  SPQKDLTQAKNGFSSVQATQLQTTQSVEGATGSAVKSDSPSTSSIPPL----NETVSAAS 664

Query: 1095 DPQAPENHSSSPGSRSLQTGGFAWEGEVENNVYSQATGVVPQHKYHPTAGSYQLQFALQQ 1154
                   HSSS        GG +   E+ N   +Q +  +   +   ++ +   + +   
Sbjct: 665  LLTTTNQHSSS-------LGGLSHSEEIPNTTTTQHSSTLSTQQNTLSSSTSSGRTSTST 717

Query: 1155 LEQQKLQSRQLLDQSRARHQAIFGSQTLPN---SNLWTMNNG--------------AGCR 1197
            L    ++S   L  S +       + + P    S   ++N+G              A  R
Sbjct: 718  LLHTSVESEANLHSSSSTFSTTSSTVSAPPPVVSVSSSLNSGSSLGLSLGSNSTVTASTR 777

Query: 1198 ISSATASGQKPTTLPQKVVPPPSSCASLVPKP 1229
             S AT SG+ P  LP  V P       L+P P
Sbjct: 778  SSVATTSGKAPPNLPPGVPP-------LLPNP 802


>gi|188497756 ubiquitin associated protein 2-like isoform b [Homo
            sapiens]
          Length = 983

 Score = 42.0 bits (97), Expect = 0.004
 Identities = 94/452 (20%), Positives = 161/452 (35%), Gaps = 71/452 (15%)

Query: 821  HSKISKNNNNYSDSGAKGDHPETIMEEVKIKPPKQQQTTEIHSD--KLSRFTTSAEKEAK 878
            HS+      +  D G+    P  +  ++K         + +HS   K   FT S+     
Sbjct: 379  HSQSGSTTTSSWDMGSTTQSPSLVQYDLK-----NPSDSAVHSPFTKRQAFTPSSTMMEV 433

Query: 879  LVYSNSSSGPTATLQKIP-NTHLSSVTTS--DLSPGPCHHSS------------------ 917
             +   S +  T+T    P ++ L S +TS   +SPG   + S                  
Sbjct: 434  FLQEKSPAVATSTAAPPPPSSPLPSKSTSAPQMSPGSSDNQSSSPQPAQQKLKQQKKKAS 493

Query: 918  -LSQIPSAIPSMPHQPTILLNTVSASASPCLHPGAQNIPSPTGLPRCRSGSHTIGPFSSF 976
              S+IP+    MP    I    +   A   L  G++ + S        S S +  P S +
Sbjct: 494  LTSKIPALAVEMPGSADISGLNLQFGA---LQFGSEPVLSDYESTPTTSASSSQAPSSLY 550

Query: 977  QSAAHIYSQKLSRPSSAKAGSCYLNKHHSGIAKTQKEGEDASLYSKRYNQSM-VTAELQR 1035
             S A   S  +S   S ++G  Y +        T +      LY +R  Q+    + +  
Sbjct: 551  TSTASESSSTISSNQSQESG--YQSGPIQSTTYTSQNNAQGPLYEQRSTQTRRYPSSISS 608

Query: 1036 LAEKQAARQYSPSSHINLLTQQVT-NLNLATGIINRSSASAPPTLRPIISPSGPTWSTQS 1094
              +K   +  +  S +     Q T ++  ATG   +S + +  ++ P+      T S  S
Sbjct: 609  SPQKDLTQAKNGFSSVQATQLQTTQSVEGATGSAVKSDSPSTSSIPPL----NETVSAAS 664

Query: 1095 DPQAPENHSSSPGSRSLQTGGFAWEGEVENNVYSQATGVVPQHKYHPTAGSYQLQFALQQ 1154
                   HSSS        GG +   E+ N   +Q +  +   +   ++ +   + +   
Sbjct: 665  LLTTTNQHSSS-------LGGLSHSEEIPNTTTTQHSSTLSTQQNTLSSSTSSGRTSTST 717

Query: 1155 LEQQKLQSRQLLDQSRARHQAIFGSQTLPN---SNLWTMNNG--------------AGCR 1197
            L    ++S   L  S +       + + P    S   ++N+G              A  R
Sbjct: 718  LLHTSVESEANLHSSSSTFSTTSSTVSAPPPVVSVSSSLNSGSSLGLSLGSNSTVTASTR 777

Query: 1198 ISSATASGQKPTTLPQKVVPPPSSCASLVPKP 1229
             S AT SG+ P  LP  V P       L+P P
Sbjct: 778  SSVATTSGKAPPNLPPGVPP-------LLPNP 802


>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
           sapiens]
          Length = 1341

 Score = 40.8 bits (94), Expect = 0.008
 Identities = 44/140 (31%), Positives = 65/140 (46%), Gaps = 27/140 (19%)

Query: 552 RKRRRRSSRLRAMRP-KYPVITQPAE-----------------MNVKTETESEEEEEVAL 593
           RK  RRSSR+R  R  K    +QPAE                  N+KTE E EEEEE   
Sbjct: 222 RKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEE 281

Query: 594 DNEDEE--QEASQEESAGFLRE--NQAKYTPSL--TALVENTPKENSMKVREWNNKGGHC 647
           D+E+EE   E  +   A  L+E   + +  P +    +++  PK  S + +E   +GG  
Sbjct: 282 DDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQE-QEVLERGGRF 340

Query: 648 CKLETQELEPKFNLMQILQD 667
            +  +QE   K +L +  Q+
Sbjct: 341 TR--SQEEARKSHLARQQQE 358



 Score = 30.8 bits (68), Expect = 8.7
 Identities = 32/112 (28%), Positives = 50/112 (44%), Gaps = 7/112 (6%)

Query: 550 EVRKRRRRSSRLRAMRPKYPVITQPAEMNVKTETESEEEEEVALDNEDEEQEASQEESAG 609
           EV +R  R +R +    K  +  Q  E  +KT +  EEEE   + +    +E S+  S  
Sbjct: 332 EVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEER-EIKSSQGLKEKSKSPSPP 390

Query: 610 FLRENQAKYTPSLTALVENTPKENS----MKVREWNNKGGHCCKLETQELEP 657
            L E++ K   SL AL E T  E      +  +E ++   H      +E+EP
Sbjct: 391 RLTEDRKK--ASLVALPEQTASEEETPPPLLTKEASSPPPHPQLHSEEEIEP 440


>gi|33946327 nucleoporin 214kDa [Homo sapiens]
          Length = 2090

 Score = 40.8 bits (94), Expect = 0.008
 Identities = 51/205 (24%), Positives = 84/205 (40%), Gaps = 19/205 (9%)

Query: 931  QPTILLNTVSASASPCLHPGAQNIPSPTGLPRCRSGSHTIGPFSSF----QSAAHIYSQK 986
            QP +  +  +AS++  +   A+  P+ TG+P  R  +  + P SSF    Q+A    +  
Sbjct: 1545 QPAVSNSGTAASSTSLVALSAEATPATTGVPDAR--TEAVPPASSFSVPGQTAVTAAAIS 1602

Query: 987  LSRPSSAKAGSCYLNKHHSGIAKTQKEGEDASLYSKRYNQSMVTAELQRLAEKQAARQYS 1046
             + P + +  S  +    + I       E A+          VT+     A+  AA   S
Sbjct: 1603 SAGPVAVETSSTPIASSTTSIVAPGPSAEAAAF-------GTVTSGSSVFAQPPAA---S 1652

Query: 1047 PSSHINLLTQQVTNLNLATGIINRSSASAPPTLRPIISPSGPTWST-QSDPQAPENHSSS 1105
             SS  N LT        AT +  + +AS  P+L      +G T ST  + PQ   +  SS
Sbjct: 1653 SSSAFNQLTNNTATAPSATPVFGQVAASTAPSL--FGQQTGSTASTAAATPQVSSSGFSS 1710

Query: 1106 PGSRSLQTGGFAWEGEVENNVYSQA 1130
            P   +   G F      + +V+ Q+
Sbjct: 1711 PAFGTTAPGVFGQTTFGQASVFGQS 1735


>gi|153085395 histone deacetylase 4 [Homo sapiens]
          Length = 1084

 Score = 40.8 bits (94), Expect = 0.008
 Identities = 62/317 (19%), Positives = 114/317 (35%), Gaps = 15/317 (4%)

Query: 725  NLQHSLRMVLPSRRLALLERRRILAHQLGDFIIVYNKETEQMAEKKSKKKVEEEEEDGVN 784
            +++    M+    +  LLE +R L     +  +      +++ + K+K+K +E       
Sbjct: 111  HIKQQQEMLAMKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTE 170

Query: 785  ME-NFQEFIRQASEAELEEVLTFYTQKNKSASVFLGTHSKISKNNNNYSDSGAKGDHPET 843
            ++   QEF+    +A     L      +         HS + +++   S      +HP  
Sbjct: 171  VKMKLQEFVLNKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVL 230

Query: 844  IMEEVKIKPPKQQQTTEIHSDKLSRFTTSAEKEAKLVYSNSSSGPTAT-LQKIPNTHLSS 902
             M + K   P ++  +E +    SR      +           GP  T L+K P     S
Sbjct: 231  GMYDAKDDFPLRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDS 290

Query: 903  VTTSDLSPGPCHHSSLS-------QIPSAIPSMPHQPTILLNTVSASASPCLHPGAQNIP 955
              +S    GP   ++ S        I  A+PS+P + ++    V+   S    P    + 
Sbjct: 291  ACSSAPGSGPSSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLP----LY 346

Query: 956  SPTGLPRCRSGSHTIGPFSSFQSAAHIYSQKLSRPSSAKAGSCYLNKHHSGIAKTQKEGE 1015
            +   LP    G    GP  S  +A    +++L+ P+  +  S +   H +    T     
Sbjct: 347  TSPSLPNITLGLPATGP--SAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLER 404

Query: 1016 DASLYSKRYNQSMVTAE 1032
            D         Q MV  E
Sbjct: 405  DGGAAHSPLLQHMVLLE 421


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 39.7 bits (91), Expect = 0.019
 Identities = 96/434 (22%), Positives = 152/434 (35%), Gaps = 84/434 (19%)

Query: 870  TTSAEKEAKLVYSNSSSGPTATLQKIPNTHLSSVTTSDLSPGPCHHSSLSQIPSAIPSMP 929
            +TS     +LV  N S+G   T+ ++P    S V+       P  +SS S          
Sbjct: 507  STSTGAATRLVTGNPSTGTAGTIPRVP----SKVSAIGEPGEPTTYSSHS---------- 552

Query: 930  HQPTILLNTVSASASPCLHPGAQNIPSPTGLPRCRSGSHTI--------GPFSSFQSAAH 981
               T L  T  A A              TG     S S+++         P SS     H
Sbjct: 553  ---TTLPKTTGAGA----QTQWTQETGTTGEALLSSPSYSVTQMIKTATSPSSSPMLDRH 605

Query: 982  IYSQKLSRPSSAKAGSCYLNKHHSGIAKTQKEGEDASLYSKRYNQSMVTAELQRLAEKQA 1041
               Q  + PS+          +HS I  T    +++   S+R +    T   Q   E Q 
Sbjct: 606  TSQQITTAPST----------NHSTIHSTSTSPQESPAVSQRGH----TQAPQTTQESQT 651

Query: 1042 ARQYSPSSHINLLTQQVTNLNLATGIINRSSASAPPTLRPIIS--------PSGPTWSTQ 1093
             R  SP +     T+ VT    +      S +   P   P IS        P+G   +TQ
Sbjct: 652  TRSVSPMTD----TKTVTTPGSSFTASGHSPSEIVPQDAPTISAATTFAPAPTGDGHTTQ 707

Query: 1094 SD----PQAPENHSS----SPGSRSLQTGGFAWEGEVENNVYSQATGVVPQHKYHPTAGS 1145
            +       AP +H +    S G+   +TG       + N+V S   G  P+ ++   + S
Sbjct: 708  APTTALQAAPSSHDATLGPSGGTSLSKTGALT----LANSVVSTPGG--PEGQWTSASAS 761

Query: 1146 YQLQFALQQLEQQKLQSRQLLDQSRARHQAIFGSQTLPNSNLWTMNNGAGCRISSATASG 1205
                 A       + +S +   Q++    A  GS+T         ++GA    S  T SG
Sbjct: 762  TSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSSSGA----SGTTPSG 817

Query: 1206 QKPTTLPQKVVPPPSSCASLVPKPPPNHEQVLRRATSQ--KASKGSSAEGQLNGLQSSLN 1263
             +  +   +     S+         P+ +    ++T++   AS    A     G+ SS+ 
Sbjct: 818  SEGISTSGETTRFSSN---------PSRDSHTTQSTTELLSASASHGAIPVSTGMASSIV 868

Query: 1264 PAAFVPITSSTDPA 1277
            P  F P  S    A
Sbjct: 869  PGTFHPTLSEASTA 882



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 53/218 (24%), Positives = 87/218 (39%), Gaps = 9/218 (4%)

Query: 879  LVYSNSSSGPTATLQKIPNTHLSSVTTSDLSPGPCHHSSLSQIPSAIPSMPHQPTILLNT 938
            L  +++SS  T     +P T LSSV+T D +P P   +S +    A P +P      ++T
Sbjct: 3953 LPVTDASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATP-LPVTSLSSVST 4011

Query: 939  VSASASPCLHPGAQNIPSPTGLPRCRSGSHTIG-----PFSSFQSAAHIYSQKLSRPSSA 993
               +  P   P + +    T LP   + S + G     P +S  SA+   +  L    ++
Sbjct: 4012 GDTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSASTGDTTPLPVTDTS 4071

Query: 994  KAGSCYLNKHHSGIAKTQKEGEDASLYSKRYNQSMVTAELQRLAEKQA--ARQYSPSSHI 1051
             A + +          +   G    L     + S+ T     LA   A  A   S  S +
Sbjct: 4072 SASTGHATPLPVTDTSSASTGHATPLPVTSLS-SVSTGHATPLAVSSATSASTVSSDSPL 4130

Query: 1052 NLLTQQVTNLNLATGIINRSSASAPPTLRPIISPSGPT 1089
             + T  +T  +L T    R++ S PPT    I  + P+
Sbjct: 4131 KMETPGMTTPSLKTDGGRRTATSPPPTTSQTIISTIPS 4168



 Score = 39.3 bits (90), Expect = 0.024
 Identities = 37/134 (27%), Positives = 56/134 (41%), Gaps = 8/134 (5%)

Query: 870  TTSAEKEAKLVYSNSSSGPTATLQKIPNTHLSSVTTSDLSPGPCHHSSLSQIPSAIPSMP 929
            + S     +L  +++SS  T     +P T LSSV+T D +P     +S      A P +P
Sbjct: 3480 SASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATP-LP 3538

Query: 930  HQPTILLNTVSASASPCLHPGA----QNIPSPTGLPRCRSGSHTIG-PFSSFQSAA--HI 982
               T   +T   +  P     +    Q  P P  +P   S  HT   P +S  S +  H+
Sbjct: 3539 VTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHV 3598

Query: 983  YSQKLSRPSSAKAG 996
                ++ PSSA  G
Sbjct: 3599 TPLHVTSPSSASTG 3612



 Score = 37.7 bits (86), Expect = 0.071
 Identities = 42/133 (31%), Positives = 57/133 (42%), Gaps = 16/133 (12%)

Query: 867  SRFTTSAEKEAKLVYSNSSSGPTATLQKIPNTHLSSVTTSDLSPGPCHHSSLSQIPSAIP 926
            S  + S      L  +++SS  T     +P T LSSV+T D +P P    S +    A P
Sbjct: 3013 STSSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATP 3072

Query: 927  SMPHQPTILLNTVSASASPCLHPGAQNIPSP-TGLPRCRSGSHTIGPFSSFQSAA--HIY 983
                    LL T ++SAS       Q  P P T L    +G  T  P +S  SA+  H  
Sbjct: 3073 --------LLVTDASSAST-----GQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHAT 3119

Query: 984  SQKLSRPSSAKAG 996
            S  ++  SSA  G
Sbjct: 3120 SLPVTDTSSASTG 3132



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 36/125 (28%), Positives = 54/125 (43%), Gaps = 8/125 (6%)

Query: 879  LVYSNSSSGPTATLQKIPNTHLSSVTTSDLSPGPCHHSSLSQIPSAIPSMPHQPTILLNT 938
            L  +++SS  T     +P T LSSV+T D +P P    S +      P +P   T   +T
Sbjct: 2945 LPVTDTSSASTGHATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHTTP-LPVTDTSSAST 3003

Query: 939  VSASASPCLHPGAQNIPSPTGLPRCRSGSHTIG-----PFSSFQSAAHIYSQKL--SRPS 991
              A+A P     + +    T LP   + S + G     P +S  S +   +  L  + PS
Sbjct: 3004 GQATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPS 3063

Query: 992  SAKAG 996
            SA  G
Sbjct: 3064 SASTG 3068



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 37/134 (27%), Positives = 56/134 (41%), Gaps = 8/134 (5%)

Query: 870  TTSAEKEAKLVYSNSSSGPTATLQKIPNTHLSSVTTSDLSPGPCHHSSLSQIPSAIPSMP 929
            + S     +L  ++ SS  T     +P T+ SSV+T D  P P    S +    A P +P
Sbjct: 3240 SASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDTMPLPVTSPSSASTGHATP-LP 3298

Query: 930  HQPTILLNTVSASASPCLHPGAQNIPSPTGLPRCRSGSHTIG-----PFSSFQSAA--HI 982
               T   +T  A+  P     + +    T LP   + S + G     P +S  SA+  H 
Sbjct: 3299 VTSTSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSSASTGDTTPLPVTSPSSASTGHT 3358

Query: 983  YSQKLSRPSSAKAG 996
                ++ PSSA  G
Sbjct: 3359 TPLHVTIPSSASTG 3372



 Score = 34.7 bits (78), Expect = 0.60
 Identities = 36/126 (28%), Positives = 58/126 (46%), Gaps = 10/126 (7%)

Query: 879  LVYSNSSSGPTATLQKIPNTHLSSVTTSDLSPGPCHHSS------LSQIPSAIP-SMPHQ 931
            L  +++SS  T     +P T LSSV+T D +P P   +S       + +P  IP S+   
Sbjct: 3665 LPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDASSASTGHATPLPVTIPSSVSTG 3724

Query: 932  PTILLNTVSASASPCLHPGAQNIPSPTGLPRCRSGSHTIGPFSSFQSAAHIYSQKLSRPS 991
             T+ L   S S++   H  A  +P  TGL    +G  T  P +   SA+  ++  L    
Sbjct: 3725 DTMPLPVTSPSSASTGH--ATPLP-VTGLSSASTGDTTPLPVTDTSSASTRHATPLPVTD 3781

Query: 992  SAKAGS 997
            ++ A +
Sbjct: 3782 TSSAST 3787



 Score = 34.3 bits (77), Expect = 0.79
 Identities = 36/134 (26%), Positives = 57/134 (42%), Gaps = 8/134 (5%)

Query: 870  TTSAEKEAKLVYSNSSSGPTATLQKIPNTHLSSVTTSDLSPGPCHHSSLSQIPSAIPSMP 929
            + S+     L  +++SS PT     +P T  SSV+T   +P P   +S      A P +P
Sbjct: 1944 SASSGHTTPLPVTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATP-LP 2002

Query: 930  HQPTILLNTVSASASPCLHPGAQNIPSPTGLPRCRSGSHTIG-----PFSSFQSAAHIYS 984
               T  ++T  A+  P     + +    T LP   + S + G     P +S  S +   +
Sbjct: 2003 VTDTSSVSTGQATPLPVTSLSSASTGDTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDT 2062

Query: 985  QKL--SRPSSAKAG 996
              L  + PSSA  G
Sbjct: 2063 TPLPVTSPSSASTG 2076



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 38/138 (27%), Positives = 57/138 (41%), Gaps = 16/138 (11%)

Query: 870  TTSAEKEAKLVYSNSSSGPTATLQKIPNTHLSSVTTSDLSPGP--------CHHSSLSQI 921
            + + +   +L  ++ SS  T     +P T LSSV+T D +P P          H+S   +
Sbjct: 1688 SATTDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLV 1747

Query: 922  PSAIPSMPHQPTILLNTVSASASPCLHPGAQNIPSP-TGLPRCRSGSHTIGPFSSFQSAA 980
              A  +   Q T L  T ++S S      A   P P TGL    +   T  P +   SA+
Sbjct: 1748 TDASSASTGQATPLPVTDTSSVST-----AHATPLPVTGLSSASTDDTTRLPVTDVSSAS 1802

Query: 981  --HIYSQKLSRPSSAKAG 996
                    ++ PSSA  G
Sbjct: 1803 TGQAIPLPVTSPSSASTG 1820



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 8/125 (6%)

Query: 879  LVYSNSSSGPTATLQKIPNTHLSSVTTSDLSPGPCHHSSLSQIPSAIPSMPHQPTILLNT 938
            L+ +++SS  T     +P T LSS +T D +P P   +S S       S+P      ++T
Sbjct: 2225 LLVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDAS-SVSTGHATSLPVTSLSSVST 2283

Query: 939  VSASASPCLHPGAQNIPSPTGLPRCRSGSHTIG-----PFSSFQSAAHIYSQKL--SRPS 991
               +  P   P + +    T L    + S + G     P +S  SA+   +  L  + PS
Sbjct: 2284 GDTTPLPVTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPS 2343

Query: 992  SAKAG 996
            SA  G
Sbjct: 2344 SASTG 2348



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 37/159 (23%), Positives = 60/159 (37%), Gaps = 8/159 (5%)

Query: 813  SASVFLGTHSKISKNNNNYSDSGAKGDHPETIMEEVKIKPPKQQQTTEIHSDKLSRFTTS 872
            ++SVF G  + +     + + SG     P T    V          T+  S        S
Sbjct: 2694 ASSVFTGHATSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTDASS-------VS 2746

Query: 873  AEKEAKLVYSNSSSGPTATLQKIPNTHLSSVTTSDLSPGPCHHSSLSQIPSAIPSMPHQP 932
                  L  +++SS  T     +P T LSSV+T D +P P   +S +    A P +P   
Sbjct: 2747 TGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATP-LPVTS 2805

Query: 933  TILLNTVSASASPCLHPGAQNIPSPTGLPRCRSGSHTIG 971
               ++T   +  P     + +    T LP   + S + G
Sbjct: 2806 LSSVSTGDTTPLPVTDTSSASTGHATSLPVTDTSSASTG 2844



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 1/102 (0%)

Query: 870  TTSAEKEAKLVYSNSSSGPTATLQKIPNTHLSSVTTSDLSPGPCHHSSLSQIPSAIPSMP 929
            + S      L  +++SS  T  +  +P T LSS +T D +P P   +S +    A  S+P
Sbjct: 1048 SASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHA-TSLP 1106

Query: 930  HQPTILLNTVSASASPCLHPGAQNIPSPTGLPRCRSGSHTIG 971
               T  ++T   +  P     + +    T LP   + S + G
Sbjct: 1107 VTDTSSVSTGHTTPLPVTDTSSASTGHATSLPVTDTSSVSTG 1148



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 15/97 (15%)

Query: 882  SNSSSGPTATLQKIPNTHLSSVTTSDLSPGPCHHSSLSQIPSAIPSMPHQPTILLNTVSA 941
            +++SS  T     +P T LSSV+T D +P P         PS+  +    P ++ +T SA
Sbjct: 1156 TDASSASTGQATPLPVTSLSSVSTGDTTPLPV------TSPSSASTGHATPLLVTDTSSA 1209

Query: 942  S---ASPCLHPGAQNIPS------PTGLPRCRSGSHT 969
            S   A+P     A ++ +      P  +P   S  HT
Sbjct: 1210 STGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHT 1246



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 15/97 (15%)

Query: 882  SNSSSGPTATLQKIPNTHLSSVTTSDLSPGPCHHSSLSQIPSAIPSMPHQPTILLNTVSA 941
            +++SS  T     +P T LSSV+T D +P P         PS+  +    P ++ +T SA
Sbjct: 1364 TDASSASTGQATPLPVTSLSSVSTGDTTPLPV------TSPSSASTGHATPLLVTDTSSA 1417

Query: 942  S---ASPCLHPGAQNIPS------PTGLPRCRSGSHT 969
            S   A+P     A ++ +      P  +P   S  HT
Sbjct: 1418 STGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHT 1454



 Score = 31.2 bits (69), Expect = 6.7
 Identities = 33/122 (27%), Positives = 51/122 (41%), Gaps = 8/122 (6%)

Query: 882  SNSSSGPTATLQKIPNTHLSSVTTSDLSPGPCHHSSLSQIPSAIPSMPHQPTILLNTVSA 941
            +++SS  T     +P T LSS +T D +  P    S +    A P +P   T  ++T   
Sbjct: 3220 TDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATP-LPVTNTSSVSTGDT 3278

Query: 942  SASPCLHPGAQNIPSPTGLPRCRSGSHTIG-----PFSSFQSAA--HIYSQKLSRPSSAK 994
               P   P + +    T LP   + S + G     P +S  SA+  H     ++  SSA 
Sbjct: 3279 MPLPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSSAS 3338

Query: 995  AG 996
             G
Sbjct: 3339 TG 3340



 Score = 31.2 bits (69), Expect = 6.7
 Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 7/96 (7%)

Query: 879  LVYSNSSSGPTATLQKIPNTHLSSVTTSDLSPGPCHHSSLSQIPSAIPSMPHQPTILLNT 938
            L  +++SS  T     +P T LSSV+T D +P P   +S +    A P     P   L++
Sbjct: 3393 LPVTDTSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASSASTGQATP----LPVTSLSS 3448

Query: 939  VS-ASASPCLHPGAQNIPS--PTGLPRCRSGSHTIG 971
            VS    +P L   A ++ +   T LP   + S + G
Sbjct: 3449 VSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTG 3484



 Score = 30.8 bits (68), Expect = 8.7
 Identities = 44/162 (27%), Positives = 62/162 (38%), Gaps = 24/162 (14%)

Query: 857  QTTEIHSDKLSRFTTSAEKEAKLVYSNSSSGPTATLQKIPNTHLSSVTTSDLSPGPCHHS 916
            Q T +    LS  +T       L  +++SS  T     +P T LSSV+T D +P P    
Sbjct: 2013 QATPLPVTSLSSASTG--DTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSP 2070

Query: 917  SLSQIPSAIP---------SMPHQPTILL---NTVSASASPCLH-------PGAQNIPSP 957
            S +    A P         S  H  ++L+   ++VS   +  LH             P P
Sbjct: 2071 SSASTGHATPLLVTDASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTPLP 2130

Query: 958  TGLPRCRS-GSHTIGPF--SSFQSAAHIYSQKLSRPSSAKAG 996
               P   S G  T  P   +S  S  H  S  ++  SSA  G
Sbjct: 2131 VTSPSSASTGDTTPLPVTDTSSVSTGHATSLPVTDTSSASTG 2172



 Score = 30.8 bits (68), Expect = 8.7
 Identities = 40/142 (28%), Positives = 58/142 (40%), Gaps = 16/142 (11%)

Query: 857  QTTEIHSDKLSRFTTSAEKEAKLVYSNSSSGPTATLQKIPNTHLSSVTTSDLSPGPCHHS 916
            Q T +    LS  +T       L  +++SS  T     +P T LSSV+T D +P P    
Sbjct: 2237 QATPLPVTSLSSASTG--DTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSP 2294

Query: 917  SLSQIPSAIPSMPHQPTILLNTVSASASPCLHPGAQNIPSPTGLPRCRSGSHTIGPFSSF 976
            S +    A P         L+   AS++   H  A  +P  T L    +G  T  P +S 
Sbjct: 2295 SSASTGHATP---------LHVTDASSASTGH--ATPLP-VTSLSSASTGDTTPLPVTSP 2342

Query: 977  QSAA--HIYSQKLSRPSSAKAG 996
             SA+  H     ++  SS   G
Sbjct: 2343 SSASTGHATPLHVTDASSVSTG 2364


>gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]
          Length = 495

 Score = 39.7 bits (91), Expect = 0.019
 Identities = 78/348 (22%), Positives = 141/348 (40%), Gaps = 35/348 (10%)

Query: 472 VKEEND---RRGGFIRIFPTSETWEIYGSYLEHKTSMNYMLAT-RLFQDRMTADGAPELK 527
           V+ END   +R  F+R+   +E +E+       K   N  L   +L Q+   A    +LK
Sbjct: 43  VQNENDNRVQRKQFLRLLQ-NEQFELDMEEAIQKAEENKRLKELQLKQEEKLAMELAKLK 101

Query: 528 IESLNSKAKLHAALYERKLLSLEVRKRRRRSSRLRAMRPKYPVITQPAEMNVKTETESEE 587
            ESL  + K+   + E    S+E+R+  ++   L+A         Q AE +     + + 
Sbjct: 102 HESLKDE-KMRQQVREN---SIELRELEKK---LKAAYMNKERAAQIAEKDAIKYEQMKR 154

Query: 588 EEEVALDNEDEEQEASQEESAGFLRENQAK--YTPSLTALVENTPKENSMKVREWNNKGG 645
           + E+A    +E +   +EE+A   + N+AK  Y   L   +E   K+      +   +  
Sbjct: 155 DAEIAKTMMEEHKRIIKEENAAEDKRNKAKAQYYLDLEKQLEEQEKKKQEAYEQLLKE-- 212

Query: 646 HCCKLETQELEPKFNLMQILQDNGNLSKMQARIAFSAYLQHVQIRLMKDSGGQ------- 698
              KL   E+  K      L+    L KM A   +    Q  Q    K    +       
Sbjct: 213 ---KLMIDEIVRKIYEEDQLEKQQKLEKMNAMRRYIEEFQKEQALWRKKKREEMEEENRK 269

Query: 699 --TFSASWAAKEDEQMELVVRFLKR---ASNNLQHSLRMVLPSRRLALLERRRILAHQLG 753
              F+     +E+++M  V    ++     N L   L  +L  R      R+ +   +  
Sbjct: 270 IIEFANMQQQREEDRMAKVQENEEKRLQLQNALTQKLEEMLRQREDLEQVRQELYQEEQA 329

Query: 754 DFIIVYNKETEQMAEKKSKKKVEEEEEDGVNMENFQEFIRQASEAELE 801
           +   +Y  + ++ AEKK +K+ +E ++D       +E + QA++ E E
Sbjct: 330 E---IYKSKLKEEAEKKLRKQ-KEMKQDFEEQMALKELVLQAAKEEEE 373


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.128    0.369 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,125,958
Number of Sequences: 37866
Number of extensions: 2407632
Number of successful extensions: 15949
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 73
Number of HSP's successfully gapped in prelim test: 323
Number of HSP's that attempted gapping in prelim test: 13634
Number of HSP's gapped (non-prelim): 2031
length of query: 1281
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1167
effective length of database: 13,930,794
effective search space: 16257236598
effective search space used: 16257236598
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.