Guide to the Human Genome
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Name: HDAC4 Sequence: fasta or formatted (1084aa) NCBI GI: 153085395
Description:

histone deacetylase 4

Referenced in:

Histones, Related Proteins, and Modifying Enzymes

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.8         95           2
 C cysteine            1.3         14           1
 D aspartate           3.4         37           2
 E glutamate           7.7         84           3
 F phenylalanine       2.3         25           2
 G glycine             6.5         71           2
 H histidine           4.1         44           2
 I isoleucine          2.4         26           2
 K lysine              4.5         49           3
 L leucine            11.4        124           3
 M methionine          1.9         21           1
 N asparagine          2.7         29           2
 P proline             7.9         86           2
 Q glutamine           8.4         91           4
 R arginine            5.6         61           2
 S serine              8.3         90           4
 T threonine           4.3         47           2
 V valine              6.2         67           2
 W tryptophan          0.5          5           1
 Y tyrosine            1.7         18           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   histone deacetylase 4 
HDAC5                 0.553   histone deacetylase 5 isoform 1 
HDAC5                 0.551   histone deacetylase 5 isoform 3 
HDAC9                 0.523   histone deacetylase 9 isoform 5 
HDAC9                 0.518   histone deacetylase 9 isoform 4 
HDAC9                 0.501   histone deacetylase 9 isoform 1 
HDAC9                 0.397   histone deacetylase 9 isoform 2 
HDAC7                 0.381   histone deacetylase 7 isoform a 
HDAC7                 0.365   histone deacetylase 7 isoform d 
HDAC9                 0.219   histone deacetylase 9 isoform 3 
HDAC6                 0.129   histone deacetylase 6 
HDAC10                0.100   histone deacetylase 10 isoform 1 
HDAC10                0.085   histone deacetylase 10 isoform 2 
HDAC8                 0.038   histone deacetylase 8 
HDAC1                 0.037   histone deacetylase 1 
HDAC2                 0.036   histone deacetylase 2 
HDAC3                 0.029   histone deacetylase 3 
HDAC11                0.017   histone deacetylase 11 isoform 2 
HDAC11                0.017   histone deacetylase 11 isoform 1 
MAP4K4                0.016   mitogen-activated protein kinase kinase kinase kinas...
ZNF853                0.015   zinc finger protein 853 
MED15                 0.015   mediator complex subunit 15 isoform b 
MED15                 0.014   mediator complex subunit 15 isoform a 
FOXP2                 0.014   forkhead box P2 isoform I 
FOXP2                 0.014   forkhead box P2 isoform II 
MAP4K4                0.014   mitogen-activated protein kinase kinase kinase kinas...
MLL2                  0.014   myeloid/lymphoid or mixed-lineage leukemia 2 
FOXP2                 0.014   forkhead box P2 isoform III 
TOX3                  0.014   TOX high mobility group box family member 3 isoform...
TOX3                  0.014   TOX high mobility group box family member 3 isoform...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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