TOP2A 11590

Name: TOP2A	Sequence: fasta or formatted (1531aa)		NCBI GI: 19913406
Description: DNA topoisomerase II, alpha isozyme		Referenced in: Replication Proteins
Composition: Amino acid Percentage Count Longest homopolymer A alanine 4.7 72 2 C cysteine 0.8 13 1 D aspartate 6.7 103 3 E glutamate 8.0 123 3 F phenylalanine 3.8 58 2 G glycine 5.5 84 2 H histidine 1.6 24 2 I isoleucine 5.5 84 3 K lysine 11.7 179 3 L leucine 8.0 123 2 M methionine 2.5 39 2 N asparagine 5.2 79 2 P proline 4.8 74 2 Q glutamine 3.7 56 2 R arginine 4.4 67 2 S serine 6.9 105 3 T threonine 5.9 91 3 V valine 6.3 96 2 W tryptophan 1.2 18 1 Y tyrosine 2.8 43 2			Comparative genomics: Search single species RefSeq proteins at NCBI H. sapiens M. musculus D. rerio C. intestinalis S. purpuratus D. melanogaster C. elegans A. thaliana S. cerevisiae E. coli W3110 A. pernix K1 Search summary Figure data Additional searches of RefSeq proteins at NCBI All Eukaryotes Bacteria Archaea Viruses Primates Mammals Vertebrates
Related human proteins: Protein Relative score Description Self-match 1.000 DNA topoisomerase II, alpha isozyme TOP2B 0.685 DNA topoisomerase II, beta isozyme CYLC1 0.016 cylicin, basic protein of sperm head cytoskeleton 1... NOLC1 0.015 nucleolar and coiled-body phosphoprotein 1 NEFH 0.012 neurofilament, heavy polypeptide 200kDa TRDN 0.011 triadin SETD1A 0.010 SET domain containing 1A ATRX 0.010 transcriptional regulator ATRX isoform 2 ATRX 0.010 transcriptional regulator ATRX isoform 1 RBBP6 0.009 retinoblastoma-binding protein 6 isoform 2 RBBP6 0.009 retinoblastoma-binding protein 6 isoform 1 IWS1 0.009 IWS1 homolog NCL 0.009 nucleolin CTR9 0.008 SH2 domain binding protein 1 ARID4A 0.008 retinoblastoma-binding protein 1 isoform III ARID4A 0.008 retinoblastoma-binding protein 1 isoform II ARID4A 0.008 retinoblastoma-binding protein 1 isoform I CYLC2 0.008 cylicin 2 DSPP 0.008 dentin sialophosphoprotein preproprotein MLLT1 0.008 myeloid/lymphoid or mixed-lineage leukemia (trithora... UNC13A 0.008 unc-13 homolog A PCLO 0.007 piccolo isoform 2 PCLO 0.007 piccolo isoform 1 NEFM 0.007 neurofilament, medium polypeptide 150kDa isoform 1 ... NEFM 0.007 neurofilament, medium polypeptide 150kDa isoform 2 ... BOD1L 0.007 biorientation of chromosomes in cell division 1-like... GTF2F1 0.007 general transcription factor IIF, polypeptide 1, 74... THOC2 0.007 THO complex 2 PNN 0.007 pinin, desmosome associated protein EIF5B 0.007 eukaryotic translation initiation factor 5B Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.