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Search of human proteins with 5032069
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
(424 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 927 0.0
gi|160707881 formin 2 [Homo sapiens] 127 1e-29
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 125 7e-29
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 125 7e-29
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 125 7e-29
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 121 1e-27
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 119 4e-27
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 117 2e-26
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 114 2e-25
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 114 2e-25
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s... 110 2e-24
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens] 110 3e-24
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 109 4e-24
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 107 2e-23
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 107 2e-23
gi|7706501 WW domain binding protein 11 [Homo sapiens] 106 5e-23
gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Hom... 105 1e-22
gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo... 105 1e-22
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 104 1e-22
gi|188219593 TIA1 protein isoform 1 [Homo sapiens] 100 2e-21
gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens] 100 3e-21
gi|42544123 splicing factor 1 isoform 3 [Homo sapiens] 99 7e-21
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 99 7e-21
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 99 7e-21
gi|21389357 MAPK-interacting and spindle-stabilizing protein [Ho... 99 9e-21
gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens] 97 4e-20
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 97 4e-20
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 97 4e-20
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 97 4e-20
gi|150417989 cyclin K isoform 1 [Homo sapiens] 96 5e-20
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 927 bits (2396), Expect = 0.0
Identities = 424/424 (100%), Positives = 424/424 (100%)
Query: 1 MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVE 60
MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVE
Sbjct: 1 MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVE 60
Query: 61 FLSEEDADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTF 120
FLSEEDADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTF
Sbjct: 61 FLSEEDADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTF 120
Query: 121 SAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKK 180
SAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKK
Sbjct: 121 SAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKK 180
Query: 181 DSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPP 240
DSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPP
Sbjct: 181 DSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPP 240
Query: 241 GSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGG 300
GSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGG
Sbjct: 241 GSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGG 300
Query: 301 MPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGS 360
MPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGS
Sbjct: 301 MPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGS 360
Query: 361 PMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRG 420
PMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRG
Sbjct: 361 PMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRG 420
Query: 421 PLPQ 424
PLPQ
Sbjct: 421 PLPQ 424
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 127 bits (320), Expect = 1e-29
Identities = 97/252 (38%), Positives = 112/252 (44%), Gaps = 48/252 (19%)
Query: 212 ADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPP----AMPPPPMP 267
A PPPP P G+G+PPP P PPP P PGA P PP +PPPP
Sbjct: 1006 AGIPPPPPLP-------GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1058
Query: 268 PGAAGHGPPSAGTPGAGHP------GHGHSHPHPFPPGGMPHPG-MSQMQLAHHGP-HGL 319
PGA PP PGAG P G G P P P G+P P + + + P G
Sbjct: 1059 PGAGI--PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGA 1116
Query: 320 GHPHAGPPGSGGQPPPRPPPGMPHPGPPPM---GMPPRGPPFGSPMGHPGPMPPHGMRGP 376
G P P G PPP P PG P PPP+ G+PP P G+ + P P+P G+ P
Sbjct: 1117 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPP 1176
Query: 377 PPL-------MPPHGYTGPPRPPPYGYQRGPLPPP------RPTPRPPVPPRG------- 416
PPL PP G P PPP P PPP P P PP+PP G
Sbjct: 1177 PPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPP 1236
Query: 417 --PLRGP--LPQ 424
P+ GP LPQ
Sbjct: 1237 LLPVSGPPLLPQ 1248
Score = 125 bits (315), Expect = 6e-29
Identities = 92/238 (38%), Positives = 104/238 (43%), Gaps = 43/238 (18%)
Query: 215 PPPPSAPNPVVSSLGSG-------------LPPPGMPPPGS-FPPPVPPPGA----LPPG 256
PPPP P V +L S LPPP P PG+ PPP P PGA LPP
Sbjct: 878 PPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPL 937
Query: 257 IPPAMPPPPMPPGAAGHGPPSAGTPGAGHP------GHGHSHPHPFPPGGMPHPGMSQMQ 310
+PPPP PGAA PP PGAG P G G P P P G+P P
Sbjct: 938 PGAGIPPPPPLPGAAI--PPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLP-- 993
Query: 311 LAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPM---GMPPRGPPFGSPMGHPGP 367
G G P P G PPP P PG P PPP+ G+PP P G+ + P P
Sbjct: 994 -------GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1046
Query: 368 MPPHGMRGPPPL-----MPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRG 420
+P G+ PPPL PP G PPP +PPP P P +PP PL G
Sbjct: 1047 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1104
Score = 110 bits (274), Expect = 3e-24
Identities = 84/232 (36%), Positives = 96/232 (41%), Gaps = 42/232 (18%)
Query: 215 PPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIP----PAMPP------- 263
P PP P + S +P GM P PPP P PG P +P P PP
Sbjct: 856 PSPPPLP---CTESSSSMPGLGMVP----PPPPPLPGMTVPTLPSTAIPQPPPLQGTEML 908
Query: 264 PPMPPGAAGHG-PPSAGTPGAG------HPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGP 316
PP PP G G PP PGAG PG G P P P +P P
Sbjct: 909 PPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLP-------- 960
Query: 317 HGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPM---GMPPRGPPFGSPMGHPGPMPPHGM 373
G G P P G PPP P PG P PPP+ G+PP P G+ + P P+P G+
Sbjct: 961 -GAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1019
Query: 374 RGPPPL-----MPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRG 420
PPPL PP G PPP +PPP P P +PP PL G
Sbjct: 1020 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1071
Score = 107 bits (268), Expect = 2e-23
Identities = 79/207 (38%), Positives = 89/207 (42%), Gaps = 31/207 (14%)
Query: 212 ADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPP----AMPPPPMP 267
A PPPP P G+G+PPP P PPP P PGA P PP +PPPP
Sbjct: 1083 AGIPPPPPLP-------GAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1135
Query: 268 PGAAGHGPPSAGTPGAGHP----GHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPH 323
PGA PP G P G G P P P G+P P G+G P
Sbjct: 1136 PGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP---------GVGIPP 1186
Query: 324 AGPPGSGGQPPPRPPPGMPHPGPPP---MGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLM 380
P G PPP P PG P PPP MG+PP P P G P PP PPL+
Sbjct: 1187 PPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLL 1246
Query: 381 PPHGYTGPPRPPPYGYQRGPLPPPRPT 407
P G + P P G+ LPPP P+
Sbjct: 1247 PQVGSSTLPTPQVCGF----LPPPLPS 1269
Score = 97.4 bits (241), Expect = 2e-20
Identities = 81/215 (37%), Positives = 93/215 (43%), Gaps = 36/215 (16%)
Query: 212 ADAPPPPSAPN----PVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPP----AMPP 263
A PPPP P P G+G+PPP P PPP P PGA P PP +PP
Sbjct: 1094 AGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPP 1153
Query: 264 PPMPPGAAGHGPPSAGTPGAGHP------GHGHSHPHPFPPGGMPHPGMSQMQLAHHGPH 317
PP PGA PP PGAG P G G P P P G+P P
Sbjct: 1154 PPPLPGAGI--PPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLP--------- 1202
Query: 318 GLGHPHAGP-PGSGGQPPPRPPPGMPHPG---PPPMGMPPRGPPFGSPMGHPGPMPPHGM 373
G G P P PG G P P PP +P PG PPP +P GPP +G +P +
Sbjct: 1203 GAGIPPPPPLPGMGIPPAPAPP--LPPPGTGIPPPPLLPVSGPPLLPQVG-SSTLPTPQV 1259
Query: 374 RG--PPPLMPPHGYTGPPRPPPYGYQRGPLPPPRP 406
G PPPL P G G G ++ P+ P RP
Sbjct: 1260 CGFLPPPL--PSGLFGLGMNQDKGSRKQPIEPCRP 1292
Score = 68.9 bits (167), Expect = 8e-12
Identities = 59/178 (33%), Positives = 71/178 (39%), Gaps = 22/178 (12%)
Query: 262 PPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGH 321
PPPP +AG G P + P + SH H + + + P
Sbjct: 811 PPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEH-----SVSSAFKNSCNIPSPPPLPCTE 865
Query: 322 PHAGPPGSGGQPPPRPP-PGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPP---HGMRGPP 377
+ PG G PPP PP PGM P P +P P G+ M P P PP G+ PP
Sbjct: 866 SSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEM-LPPPPPPLPGAGIPPPP 924
Query: 378 PL-------MPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRG-----PLP 423
PL +PP G P PPP P PPP P P+PP P G PLP
Sbjct: 925 PLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLP 982
Score = 30.4 bits (67), Expect = 3.2
Identities = 53/208 (25%), Positives = 64/208 (30%), Gaps = 32/208 (15%)
Query: 184 GERHGSA-AERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGS 242
GE GS E+ L+A + D P L A+ P P+P GLP P
Sbjct: 261 GEAPGSPDTEQALSALS-----DLPESLAAEPREPQQPPSP------GGLPVSEAPSL-- 307
Query: 243 FPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMP 302
P P A A P P PG G P G G + P G P
Sbjct: 308 ---PAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFED--APRGSP 362
Query: 303 HPGMSQMQLAHHGPHGLGH--------PHAGPPGS-GGQPPPRPPPGMPHPGPPPMGMPP 353
+ ++ P LG P A S G P P P+P P +
Sbjct: 363 GEEWAP-EVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKT 421
Query: 354 RGPPFGSPMGHPGPMP---PHGMRGPPP 378
SP P P P R P P
Sbjct: 422 TTRQLSSPNHSPSQSPNQSPRIKRRPEP 449
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 125 bits (314), Expect = 7e-29
Identities = 75/183 (40%), Positives = 107/183 (58%), Gaps = 7/183 (3%)
Query: 13 ATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIK 72
A++YVG L V+E +L+E F AGPV++ + +D +T + GY +V F DA+ A+
Sbjct: 11 ASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALD 70
Query: 73 IMNMIKLYGKPIRV--NKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTP 130
MN + GKPIR+ ++ + VG N+FI NLD ID K LYDTFSAFG IL
Sbjct: 71 TMNFDVIKGKPIRIMWSQRDPSLRKSGVG-NVFIKNLDKSIDNKALYDTFSAFGNILSCK 129
Query: 131 KIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVS-YAFKKDSKGERHGS 189
+ D SKGYAF++F + +A+D AIE MNG L +R + V + +K+ + E
Sbjct: 130 VVC---DENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAK 186
Query: 190 AAE 192
A E
Sbjct: 187 AKE 189
Score = 88.2 bits (217), Expect = 1e-17
Identities = 82/298 (27%), Positives = 130/298 (43%), Gaps = 43/298 (14%)
Query: 15 VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIM 74
VY+ E+V + L ELF Q G ++ + +D G+ +G+GFV + EDA+ A++ M
Sbjct: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEM 251
Query: 75 NMIKLYGKPIRVNKASAH-NKNLDV----------------GANIFIGNLDPEIDEKLLY 117
N ++ GK I V +A + ++ G N++I NLD ID++ L
Sbjct: 252 NGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLR 311
Query: 118 DTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYA 177
FS FG I ++ D G SKG+ F+ F+S + + A+ MNG+ + ++P+ V+ A
Sbjct: 312 KEFSPFGSITSAKVMLED---GRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALA 368
Query: 178 FKKDSKGER------HGSAAERLLAAQNPLSQADR-------PHQLFADAPPPPSAPNPV 224
+K+ + A R L A L+Q P A PP PN +
Sbjct: 369 QRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQL 428
Query: 225 VSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGA-AGHGPPSAGTP 281
+ G P G +P I + P P + A G+ P S G P
Sbjct: 429 AQMRPNPRWQQGGRPQGF--------QGMPSAIRQSGPRPTLRHLAPTGNAPASRGLP 478
Score = 87.0 bits (214), Expect = 3e-17
Identities = 56/183 (30%), Positives = 98/183 (53%), Gaps = 11/183 (6%)
Query: 5 PISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSE 64
P ++ V++ LD+ + L++ F G +++ + D +GY FV F ++
Sbjct: 91 PSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQ 148
Query: 65 EDADYAIKIMNMIKLYGKPIRVNK-ASAHNKNLDVGA------NIFIGNLDPEIDEKLLY 117
E AD AI+ MN + L + + V + S + ++GA N++I N E+D++ L
Sbjct: 149 EAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLK 208
Query: 118 DTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYA 177
+ FS FG L K+MRDP+ G SKG+ F+++ + ++ A+E MNG+ + + I V A
Sbjct: 209 ELFSQFGKTLSV-KVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRA 266
Query: 178 FKK 180
KK
Sbjct: 267 QKK 269
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 125 bits (314), Expect = 7e-29
Identities = 75/183 (40%), Positives = 107/183 (58%), Gaps = 7/183 (3%)
Query: 13 ATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIK 72
A++YVG L V+E +L+E F AGPV++ + +D +T + GY +V F DA+ A+
Sbjct: 11 ASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALD 70
Query: 73 IMNMIKLYGKPIRV--NKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTP 130
MN + GKPIR+ ++ + VG N+FI NLD ID K LYDTFSAFG IL
Sbjct: 71 TMNFDVIKGKPIRIMWSQRDPSLRKSGVG-NVFIKNLDKSIDNKALYDTFSAFGNILSCK 129
Query: 131 KIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVS-YAFKKDSKGERHGS 189
+ D SKGYAF++F + +A+D AIE MNG L +R + V + +K+ + E
Sbjct: 130 VVC---DENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAK 186
Query: 190 AAE 192
A E
Sbjct: 187 AKE 189
Score = 87.8 bits (216), Expect = 2e-17
Identities = 57/186 (30%), Positives = 98/186 (52%), Gaps = 21/186 (11%)
Query: 15 VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIM 74
VY+ E+V + L ELF Q G ++ + +D G+ +G+GFV + EDA+ A++ M
Sbjct: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEM 251
Query: 75 NMIKLYGKPIRVNKASAH-NKNLDV----------------GANIFIGNLDPEIDEKLLY 117
N ++ GK I V +A + ++ G N++I NLD ID++ L
Sbjct: 252 NGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLR 311
Query: 118 DTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYA 177
FS FG I ++ D G SKG+ F+ F+S + + A+ MNG+ + ++P+ V+ A
Sbjct: 312 KEFSPFGSITSAKVMLED---GRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALA 368
Query: 178 FKKDSK 183
+K+ +
Sbjct: 369 QRKEER 374
Score = 87.0 bits (214), Expect = 3e-17
Identities = 56/183 (30%), Positives = 98/183 (53%), Gaps = 11/183 (6%)
Query: 5 PISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSE 64
P ++ V++ LD+ + L++ F G +++ + D +GY FV F ++
Sbjct: 91 PSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQ 148
Query: 65 EDADYAIKIMNMIKLYGKPIRVNK-ASAHNKNLDVGA------NIFIGNLDPEIDEKLLY 117
E AD AI+ MN + L + + V + S + ++GA N++I N E+D++ L
Sbjct: 149 EAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLK 208
Query: 118 DTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYA 177
+ FS FG L K+MRDP+ G SKG+ F+++ + ++ A+E MNG+ + + I V A
Sbjct: 209 ELFSQFGKTLSV-KVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRA 266
Query: 178 FKK 180
KK
Sbjct: 267 QKK 269
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 125 bits (314), Expect = 7e-29
Identities = 75/183 (40%), Positives = 107/183 (58%), Gaps = 7/183 (3%)
Query: 13 ATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIK 72
A++YVG L V+E +L+E F AGPV++ + +D +T + GY +V F DA+ A+
Sbjct: 11 ASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALD 70
Query: 73 IMNMIKLYGKPIRV--NKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTP 130
MN + GKPIR+ ++ + VG N+FI NLD ID K LYDTFSAFG IL
Sbjct: 71 TMNFDVIKGKPIRIMWSQRDPSLRKSGVG-NVFIKNLDKSIDNKALYDTFSAFGNILSCK 129
Query: 131 KIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVS-YAFKKDSKGERHGS 189
+ D SKGYAF++F + +A+D AIE MNG L +R + V + +K+ + E
Sbjct: 130 VVC---DENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAK 186
Query: 190 AAE 192
A E
Sbjct: 187 AKE 189
Score = 89.7 bits (221), Expect = 4e-18
Identities = 99/410 (24%), Positives = 154/410 (37%), Gaps = 60/410 (14%)
Query: 15 VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIM 74
VY+ E+V + L ELF Q G ++ + +D G+ +G+GFV + EDA+ A++ M
Sbjct: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEM 251
Query: 75 NMIKLYGKPIRVNKASAH-NKNLDV----------------GANIFIGNLDPEIDEKLLY 117
N ++ GK I V +A + ++ G N++I NLD ID++ L
Sbjct: 252 NGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLR 311
Query: 118 DTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYA 177
FS FG I ++ D G SKG+ F+ F+S + + A+ MNG+ + ++P+ V+ A
Sbjct: 312 KEFSPFGSITSAKVMLED---GRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALA 368
Query: 178 FKKDSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGM 237
+K+ + + + +A L P + L P G
Sbjct: 369 QRKEERKAHLTNQYMQRVAGMRAL---------------------PANAILNQFQPAAG- 406
Query: 238 PPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFP 297
G F P VP PP P P+ G P P
Sbjct: 407 ---GYFVPAVPQAQG---------RPPYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIR 454
Query: 298 PGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPP 357
G P P + + + P G P G + P R G G+
Sbjct: 455 QSG-PRPTLRHLAPTGNAPASRGLP-TTTQRVGSECPDRLAMDFGGAGAAQQGLTDSCQS 512
Query: 358 FGSPMGHPGPMPPHGMRGPPP-LMPPHGYTGPPRPPPYGYQRGPLPPPRP 406
G P P + P + P+ Y R P Q PL P+P
Sbjct: 513 GGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQ--PLQAPQP 560
Score = 87.0 bits (214), Expect = 3e-17
Identities = 56/183 (30%), Positives = 98/183 (53%), Gaps = 11/183 (6%)
Query: 5 PISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSE 64
P ++ V++ LD+ + L++ F G +++ + D +GY FV F ++
Sbjct: 91 PSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQ 148
Query: 65 EDADYAIKIMNMIKLYGKPIRVNK-ASAHNKNLDVGA------NIFIGNLDPEIDEKLLY 117
E AD AI+ MN + L + + V + S + ++GA N++I N E+D++ L
Sbjct: 149 EAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLK 208
Query: 118 DTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYA 177
+ FS FG L K+MRDP+ G SKG+ F+++ + ++ A+E MNG+ + + I V A
Sbjct: 209 ELFSQFGKTLSV-KVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRA 266
Query: 178 FKK 180
KK
Sbjct: 267 QKK 269
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 121 bits (303), Expect = 1e-27
Identities = 72/183 (39%), Positives = 106/183 (57%), Gaps = 7/183 (3%)
Query: 13 ATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIK 72
A++YVG L V+E +L+E F AGP+++ + +D +T + GY +V F DA+ A+
Sbjct: 11 ASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALD 70
Query: 73 IMNMIKLYGKPIRV--NKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTP 130
MN + GKP+R+ ++ + VG NIFI NLD ID K LYDTFSAFG IL
Sbjct: 71 TMNFDVIKGKPVRIMWSQRDPSLRKSGVG-NIFIKNLDKSIDNKALYDTFSAFGNILSCK 129
Query: 131 KIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVS-YAFKKDSKGERHGS 189
+ D SKGY F++F + +A++ AIE MNG L +R + V + +K+ + E
Sbjct: 130 VVC---DENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAR 186
Query: 190 AAE 192
A E
Sbjct: 187 AKE 189
Score = 98.6 bits (244), Expect = 9e-21
Identities = 84/316 (26%), Positives = 128/316 (40%), Gaps = 56/316 (17%)
Query: 15 VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIM 74
VY+ E + + L +LF + GP ++ + D +G+ +G+GFV F EDA A+ M
Sbjct: 193 VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEM 251
Query: 75 NMIKLYGKPIRVNKASAHNKNLDV-----------------GANIFIGNLDPEIDEKLLY 117
N +L GK I V +A + G N+++ NLD ID++ L
Sbjct: 252 NGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLR 311
Query: 118 DTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYA 177
FS FG I +M + G SKG+ F+ F+S + + A+ MNG+ + +P+ V+ A
Sbjct: 312 KEFSPFGTITSAKVMM---EGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALA 368
Query: 178 FKKDSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGM 237
+K+ + QA +Q + PNPV++ P
Sbjct: 369 QRKEER-------------------QAHLTNQYMQRMASVRAVPNPVIN------PYQPA 403
Query: 238 PPPGSFPPPVPP----PGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHP 293
PP G F +P PP + P P P PGA P
Sbjct: 404 PPSGYFMAAIPQTQNRAAYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPA------ 457
Query: 294 HPFPPGGMPHPGMSQM 309
P PP P SQ+
Sbjct: 458 APRPPFSTMRPASSQV 473
Score = 81.3 bits (199), Expect = 2e-15
Identities = 53/183 (28%), Positives = 96/183 (52%), Gaps = 11/183 (6%)
Query: 5 PISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSE 64
P ++ +++ LD+ + L++ F G +++ + D +GYGFV F ++
Sbjct: 91 PSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQ 148
Query: 65 EDADYAIKIMNMIKLYGKPIRVNK-ASAHNKNLDVGA------NIFIGNLDPEIDEKLLY 117
E A+ AI+ MN + L + + V + S + ++GA N++I N ++D++ L
Sbjct: 149 EAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLK 208
Query: 118 DTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYA 177
D F FG L K+M D ++G SKG+ F++F + + A++ MNG+ L + I V A
Sbjct: 209 DLFGKFGPALSV-KVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRA 266
Query: 178 FKK 180
KK
Sbjct: 267 QKK 269
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 119 bits (299), Expect = 4e-27
Identities = 77/190 (40%), Positives = 114/190 (60%), Gaps = 7/190 (3%)
Query: 6 ISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEE 65
++ + + A++YVG L V+E LL+ F GPV++ + +D+VT + GY +V FL
Sbjct: 3 VAAKYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLA 62
Query: 66 DADYAIKIMNMIKLYGKPIRV--NKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAF 123
DA A+ MN + GK IR+ ++ A+ + +G N+FI NLD ID K LY+ FSAF
Sbjct: 63 DAQKALDTMNFDIIKGKSIRLMWSQRDAYLRRSGIG-NVFIKNLDKSIDNKTLYEHFSAF 121
Query: 124 GVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVS-YAFKKDS 182
G IL + K+M D D G SKGYAF++F + A+D AIE MNG+ L + V + +KD
Sbjct: 122 GKILSS-KVMSD-DQG-SKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDR 178
Query: 183 KGERHGSAAE 192
+ E A+E
Sbjct: 179 EAELRSKASE 188
Score = 77.8 bits (190), Expect = 2e-14
Identities = 56/180 (31%), Positives = 93/180 (51%), Gaps = 13/180 (7%)
Query: 9 RNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDAD 68
R+ V++ LD+ + L+E F G ++++ + D + GY FV F ++ AD
Sbjct: 94 RSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQGSK--GYAFVHFQNQSAAD 151
Query: 69 YAIKIMNMIKLYGKPIRVNK--------ASAHNKNLDVGANIFIGNLDPEIDEKLLYDTF 120
AI+ MN L G + V + A +K + N++I N ++D++ L D F
Sbjct: 152 RAIEEMNGKLLKGCKVFVGRFKNRKDREAELRSKASEF-TNVYIKNFGGDMDDERLKDVF 210
Query: 121 SAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKK 180
S +G L K+M D +G SKG+ F++F S +A+ A+E MNG+ + + I V A KK
Sbjct: 211 SKYGKTLSV-KVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKK 268
Score = 71.2 bits (173), Expect = 2e-12
Identities = 54/188 (28%), Positives = 98/188 (52%), Gaps = 21/188 (11%)
Query: 7 SERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEED 66
S+ ++ VY+ + + L ++F + G ++ + D +G+ +G+GFV F S E
Sbjct: 184 SKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDS-SGKSKGFGFVSFDSHEA 242
Query: 67 ADYAIKIMNMIKLYGKPIRVNKAS------AHNKNLDV-----------GANIFIGNLDP 109
A A++ MN + G+ I V +A A K + G ++I NLD
Sbjct: 243 AKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDD 302
Query: 110 EIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCN 169
ID++ L + FS+FG I + K+M++ G SKG+ I F+S + + A+ MNG+ L +
Sbjct: 303 TIDDEKLRNEFSSFGSISRV-KVMQEE--GQSKGFGLICFSSPEDATKAMTEMNGRILGS 359
Query: 170 RPITVSYA 177
+P++++ A
Sbjct: 360 KPLSIALA 367
Score = 39.3 bits (90), Expect = 0.007
Identities = 24/82 (29%), Positives = 39/82 (47%), Gaps = 2/82 (2%)
Query: 11 QDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYA 70
Q +Y+ LD+ + + L F G + + ++ GQ +G+G + F S EDA A
Sbjct: 291 QGVKLYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEE--GQSKGFGLICFSSPEDATKA 348
Query: 71 IKIMNMIKLYGKPIRVNKASAH 92
+ MN L KP+ + A H
Sbjct: 349 MTEMNGRILGSKPLSIALAQRH 370
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 117 bits (294), Expect = 2e-26
Identities = 92/262 (35%), Positives = 104/262 (39%), Gaps = 44/262 (16%)
Query: 198 QNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPP-----GMPPPGSFPPPVPPPGA 252
Q P Q D + P P P P + G PPP G PP G P PPP
Sbjct: 160 QGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 219
Query: 253 LPPGIPP--------AMPPPPMPPGAAGHG-------PPSAGTPGAGHPGHGHSHPHPFP 297
P G PP A PP P G G PP G P P G+ P P
Sbjct: 220 KPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 279
Query: 298 PG---GMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPP-PRPPPGMPHPGPPPMGMPP 353
PG G P G S+ + + P G P PP G QP P PPPG P PP G P
Sbjct: 280 PGKPQGPPPQGGSKSRSSRSPP---GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 336
Query: 354 RGPPFGSPMGHP-GPMPPHGMRGPPPLMPPHGYTGPPR----------PPPYGYQRGPLP 402
+GPP P G P GP P G + PP GPP+ PP G + P
Sbjct: 337 QGPP---PPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQA 393
Query: 403 PPRPTPR-PPVPPRG--PLRGP 421
PP P+ PP PP+G P R P
Sbjct: 394 PPAGQPQGPPRPPQGGRPSRPP 415
Score = 115 bits (287), Expect = 1e-25
Identities = 95/275 (34%), Positives = 104/275 (37%), Gaps = 59/275 (21%)
Query: 198 QNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPP-----GMPPPGSFPPPVPPPGA 252
Q P Q D+ P P P P + G PPP G PP G P PPP
Sbjct: 99 QGPPPQGDKSRSP-RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 157
Query: 253 LPPGIPP--------AMPPPPMPPGAAGHG-------PPSAGTPGAGHPGHGHSHPHPFP 297
P G PP + PP P G G PP G P P G+ P P
Sbjct: 158 KPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 217
Query: 298 PG---GMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPP-PRPPPGMPHPGPP-----P 348
PG G P G ++ Q A P G P PP G QP P PPPG P PP P
Sbjct: 218 PGKPQGPPPQGDNKSQSARSPP---GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 274
Query: 349 MGMPPRGPPFG-------------SPMGHPGPMPPHG---MRGPPPLM------PPHGYT 386
G PP G P G SP G P PP G +GPPP PP G
Sbjct: 275 QGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 334
Query: 387 GPPRPPPYGYQRGPLP----PPRPTPRPPVPPRGP 417
P PPP G +GP P R PP P+GP
Sbjct: 335 KPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGP 369
Score = 112 bits (280), Expect = 6e-25
Identities = 91/248 (36%), Positives = 98/248 (39%), Gaps = 47/248 (18%)
Query: 215 PPPPSAPN---PVVSSLGSGLPPPGMP---------------PPGSFPPPVPPPGALPPG 256
PPPP P P + G PPPG P PPG P P G P G
Sbjct: 72 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG 131
Query: 257 IPPAMPPPPMPPGAAGH---GPPSAGTPGAGHP-GHGHSHPHPFPPG---GMPHPGMSQM 309
PP P PP G+ GPP G P P G S PPG G P G +Q
Sbjct: 132 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQP 191
Query: 310 QLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMG----MPPRGPPFGSPMGHP 365
Q P G P PP G +P PPPG P GPPP G R PP G P G P
Sbjct: 192 Q---GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ-GPPPQGDNKSQSARSPP-GKPQGPP 246
Query: 366 --------GPMPPHGM-RGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRG 416
GP PP G +GP PP G P PPP G +GP P R P G
Sbjct: 247 PQGGNQPQGPPPPPGKPQGP----PPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPG 302
Query: 417 PLRGPLPQ 424
+GP PQ
Sbjct: 303 KPQGPPPQ 310
Score = 108 bits (270), Expect = 9e-24
Identities = 96/283 (33%), Positives = 105/283 (37%), Gaps = 77/283 (27%)
Query: 215 PPP--PSAPNPVVSSLGSGLPPPGMP---------------PPGSFPPPVPPPGALPPGI 257
PPP P P P + G PPPG P PPG P P G P G
Sbjct: 73 PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP 132
Query: 258 PPAMPPPPMPPGAAGH---GPPSAGTPGAGHP-GHGHSHPHPFPPG---GMPHPGMSQMQ 310
PP P PP G+ GPP G P P G S PPG G P G +Q Q
Sbjct: 133 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQ 192
Query: 311 LAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPH--------------------PGPPPM- 349
P G P PP G +P PPPG P GPPP
Sbjct: 193 GPPPPP---GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQG 249
Query: 350 GMPPRG--PPFGSPMGHP--------GPMPPHGMRGPPP---------LMPPHGYTGPP- 389
G P+G PP G P G P GP PP +GPPP PP GPP
Sbjct: 250 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPP 309
Query: 390 --------RPPPYGYQRGPLPPPRPTPRPPVPPRGPLRGPLPQ 424
PPP G +GP P P+ P PP P +GP PQ
Sbjct: 310 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP-QGPPPQ 351
Score = 107 bits (266), Expect = 3e-23
Identities = 93/267 (34%), Positives = 103/267 (38%), Gaps = 45/267 (16%)
Query: 195 LAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVP-----P 249
L A NP + P PP P G P PPPG P P P
Sbjct: 31 LIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQ-GGNQPQGPPPPPGKPQGPPPQGGNKP 89
Query: 250 PGALPPGIPPAMPP-------PPMPPGAAGHGPPSAGT--------PG--AGHPGHGHSH 292
G PPG P PP P PPG PP G PG G P G +
Sbjct: 90 QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 149
Query: 293 PH-PFPPG---GMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPP-PRPPPGMPHPGPP 347
P P PPG G P G ++ + + P G P PP G QP P PPPG P PP
Sbjct: 150 PQGPPPPGKPQGPPPQGDNKSRSSRSPP---GKPQGPPPQGGNQPQGPPPPPGKPQGPPP 206
Query: 348 PMGMPPRGPPFGSPMGHPGPMPPHGMR---------GPPPLMPPHGYTGPP-RPPPYGYQ 397
G P+GPP P G P PP G G P PP G P PPP G
Sbjct: 207 QGGNKPQGPP---PPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKP 263
Query: 398 RGPLPPPRPTPRPPVPPRGPLRGPLPQ 424
+GP P P+ P PP P +GP PQ
Sbjct: 264 QGPPPQGGNKPQGPPPPGKP-QGPPPQ 289
Score = 103 bits (258), Expect = 2e-22
Identities = 88/244 (36%), Positives = 94/244 (38%), Gaps = 38/244 (15%)
Query: 216 PPPSAPNPVVSSLGSGLPPPGMP-PPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGH- 273
P A NP + G P G P PPG P P G P G PP P PP G+
Sbjct: 29 PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 88
Query: 274 --GPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGG 331
GPP G P G P G P P G P Q GP GPP GG
Sbjct: 89 PQGPPPPGKP-QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 147
Query: 332 QPPPRPPPGMPHPGPPPMG----MPPRGPPFGSPMGHP--------GPMPPHGM-RGPPP 378
P PPP GPPP G R PP G P G P GP PP G +GPPP
Sbjct: 148 NKPQGPPPPGKPQGPPPQGDNKSRSSRSPP-GKPQGPPPQGGNQPQGPPPPPGKPQGPPP 206
Query: 379 L--------MPPHGYTGPP----------RPPPYGYQRGPLPPPRPTPRPPVPPRGPLRG 420
PP GPP R PP G +GP P P+ P PP G +G
Sbjct: 207 QGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPP-GKPQGPPPQGGNQPQGPPPPPGKPQG 265
Query: 421 PLPQ 424
P PQ
Sbjct: 266 PPPQ 269
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 114 bits (285), Expect = 2e-25
Identities = 67/183 (36%), Positives = 104/183 (56%), Gaps = 7/183 (3%)
Query: 13 ATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIK 72
A++YVG L V+E +L+E F AGP+++ + +D +T Y +V F +DA++A+
Sbjct: 11 ASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALD 70
Query: 73 IMNMIKLYGKPIRV--NKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTP 130
MN + GKP+R+ ++ + VG NIF+ NLD I+ K LYDT SAFG IL
Sbjct: 71 TMNFDVIKGKPVRIMWSQRDPSLRKSGVG-NIFVKNLDKSINNKALYDTVSAFGNILSCN 129
Query: 131 KIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITV-SYAFKKDSKGERHGS 189
+ D SKGY F++F + +A++ AI+ MNG L R + V + +K+ + E
Sbjct: 130 VVC---DENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKEREAELGAR 186
Query: 190 AAE 192
A E
Sbjct: 187 AKE 189
Score = 90.1 bits (222), Expect = 3e-18
Identities = 76/278 (27%), Positives = 126/278 (45%), Gaps = 26/278 (9%)
Query: 15 VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIM 74
VY+ E + + L +LF + GP ++ + D +G+ +G+GFV F EDA A+ M
Sbjct: 193 VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEM 251
Query: 75 NMIKLYGKPIRVNKASAH-NKNLDVG----------------ANIFIGNLDPEIDEKLLY 117
N +L GK I V +A + ++ N+++ NLD ID++ L
Sbjct: 252 NGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLR 311
Query: 118 DTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYA 177
FS FG I +M + G SKG+ F+ F+S + + A+ MNG+ + +P+ V+ A
Sbjct: 312 KAFSPFGTITSAKVMM---EGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALA 368
Query: 178 FKKDSK-GERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPS--APNPVVSSLGSGLPP 234
+K+ + +R+ + + +Q P F A P A S + P
Sbjct: 369 QRKEERQAYLTNEYMQRMASVRAVPNQRAPPSGYFMTAVPQTQNHAAYYPPSQIARLRPS 428
Query: 235 PGMPPPGSFPPPVP-PPGALPPGIPPAMPPPPMPPGAA 271
P G+ P P P A+ PG P +P M P ++
Sbjct: 429 PRWTAQGARPHPFQNKPSAIRPG-APRVPFSTMRPASS 465
Score = 83.2 bits (204), Expect = 4e-16
Identities = 55/183 (30%), Positives = 97/183 (53%), Gaps = 11/183 (6%)
Query: 5 PISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSE 64
P ++ ++V LD+ ++ L++ G +++ ++ D +GYGFV F +
Sbjct: 91 PSLRKSGVGNIFVKNLDKSINNKALYDTVSAFGNILSCNVVCDE--NGSKGYGFVHFETH 148
Query: 65 EDADYAIKIMNMIKLYGKPIRVNK-ASAHNKNLDVGA------NIFIGNLDPEIDEKLLY 117
E A+ AIK MN + L G+ + V + S + ++GA N++I N ++D++ L
Sbjct: 149 EAAERAIKKMNGMLLNGRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDERLK 208
Query: 118 DTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYA 177
D F FG L K+M D ++G SKG+ F++F + + A++ MNG+ L + I V A
Sbjct: 209 DLFGKFGPALSV-KVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRA 266
Query: 178 FKK 180
KK
Sbjct: 267 QKK 269
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 114 bits (284), Expect = 2e-25
Identities = 89/262 (33%), Positives = 103/262 (39%), Gaps = 39/262 (14%)
Query: 194 LLAAQN---PLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPP-----GMPPPGSFPP 245
L +AQN +SQ + P + + P P+P + G PPP G PP G P
Sbjct: 13 LSSAQNLNEDVSQEESPSLIAGN----PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKP 68
Query: 246 PVPPPGALPPGIPPA--------MPP-----PPMPPGAAGHGPPSAGTPGAGHPGHGHSH 292
PPP P G PP PP PP G GPP G P G +
Sbjct: 69 QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNR 128
Query: 293 PHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPP-PRPPPGMPHPGPPPMGM 351
P PP G P Q + G P PP G QP P PPPG P PP G
Sbjct: 129 PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGK 188
Query: 352 PPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPP---------RPPPYGYQRGPLP 402
P+GPP P G P PP G + PP GPP PPP G +GP P
Sbjct: 189 KPQGPP---PPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 245
Query: 403 PPRPTPRPPVPPRGPLRGPLPQ 424
P+ P PP P +GP Q
Sbjct: 246 QGGNKPQGPPPPGKP-QGPPAQ 266
Score = 109 bits (272), Expect = 5e-24
Identities = 90/255 (35%), Positives = 98/255 (38%), Gaps = 33/255 (12%)
Query: 198 QNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPP-----GMPPPGSFPPPVPPPGA 252
Q P Q D+ P P P P + G PPP G PP G P PPP
Sbjct: 78 QGPPPQGDKSRSP-RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPG 136
Query: 253 LPPGIPPA--------MPP-----PPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPG 299
P G PP PP PP G GPP G P G P PP
Sbjct: 137 KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPP 196
Query: 300 GMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPP-PRPPPGMPHPGPPPMGMPPRG-PP 357
G P Q + G P PP G QP P PPPG P PP G P+G PP
Sbjct: 197 GKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 256
Query: 358 FGSPMGHP--GPMPPHGMRGPP--PLMPP----HGYTGPPRPPPYGYQRGPLPPPRPTPR 409
G P G P G R PP P PP + GPP PP G + P PP P+
Sbjct: 257 PGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPP-PPAGGNPQQPQAPPAGQPQ 315
Query: 410 -PPVPPRG--PLRGP 421
PP PP+G P R P
Sbjct: 316 GPPRPPQGGRPSRPP 330
Score = 105 bits (262), Expect = 8e-23
Identities = 86/257 (33%), Positives = 95/257 (36%), Gaps = 37/257 (14%)
Query: 195 LAAQNPLSQADRPHQLFADAPPPPSAPN---PVVSSLGSGLPPPGMP------------- 238
L A NP + + PPPP P P + G PPPG P
Sbjct: 31 LIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSP 90
Query: 239 --PPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGH---GPPSAGTPGAGHPGHGHSHP 293
PPG P P G P G PP P PP G+ GPP G P G P G
Sbjct: 91 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKP-QGPPPQGDKSR 149
Query: 294 HPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPP 353
P P G P Q GP GPP GG+ P PPP GPPP G
Sbjct: 150 SPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKS 209
Query: 354 RGPPFGSPMGHPGPMPPHG---MRGPPPL------MPPHGYTGPPRPPPYGYQRGPL--- 401
R SP G P PP G +GPPP PP G P PPP G +GP
Sbjct: 210 RSSQ--SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQG 267
Query: 402 -PPPRPTPRPPVPPRGP 417
+ PP P+GP
Sbjct: 268 GSKSQSARSPPGKPQGP 284
Score = 100 bits (249), Expect = 2e-21
Identities = 81/228 (35%), Positives = 89/228 (39%), Gaps = 36/228 (15%)
Query: 215 PPP--PSAPNPVVSSLGSGLPPPGMP---------------PPGSFPPPVPPPGALPPGI 257
PPP P P P + G PPPG P PPG P P G P G
Sbjct: 113 PPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP 172
Query: 258 PPAMPPPPMPPGAAG---HGPPSAGTPGAGHPGHGHSHPHPFPPG---GMPHPGMSQMQL 311
PP P PP G GPP G P P S PPG G P G +Q Q
Sbjct: 173 PPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQ- 231
Query: 312 AHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMG----MPPRGPPFGSPMGHPGP 367
GP GPP GG P PPP GPP G R PP G P G P
Sbjct: 232 ---GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPP-GKPQG-PPQ 286
Query: 368 MPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPR 415
+ +GPPP P G P+ PP G +GP PP+ RP PP+
Sbjct: 287 QEGNNPQGPPP--PAGGNPQQPQAPPAGQPQGPPRPPQ-GGRPSRPPQ 331
>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
sapiens]
Length = 614
Score = 110 bits (276), Expect = 2e-24
Identities = 71/189 (37%), Positives = 103/189 (54%), Gaps = 9/189 (4%)
Query: 13 ATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIK 72
A++YVG L V+E +L+E F AGP+++ + +D T + GY ++ F DA+ A+
Sbjct: 11 ASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALD 70
Query: 73 IMNMIKLYGKPIRV--NKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTP 130
MN L G+PIR+ ++ + VG NIFI NL+ ID K LYDTFS FG IL
Sbjct: 71 TMNFEMLKGQPIRIMWSQRDPGLRKSGVG-NIFIKNLEDSIDNKALYDTFSTFGNILSCK 129
Query: 131 KIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKGERHGSA 190
D S+G+ F++F + +A+ AI MNG L +R + V + FK S+ ER
Sbjct: 130 VAC---DEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGH-FK--SRREREAEL 183
Query: 191 AERLLAAQN 199
R L N
Sbjct: 184 GARALEFTN 192
Score = 89.0 bits (219), Expect = 8e-18
Identities = 74/273 (27%), Positives = 122/273 (44%), Gaps = 31/273 (11%)
Query: 15 VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIM 74
+YV L V E L +LF Q G +++ + +D +G + +GFV F E+A A+ M
Sbjct: 193 IYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVVHM 251
Query: 75 NMIKLYGKPIRVNKASAHNKNLDV-----------------GANIFIGNLDPEIDEKLLY 117
N ++ G+ + +A + + G N+++ NLD ID+ L
Sbjct: 252 NGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLR 311
Query: 118 DTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYA 177
FS +GVI K+M + G+SKG+ F+ F+S + + A+ MNG+ + +P+ V+ A
Sbjct: 312 KEFSPYGVITSA-KVMTEG--GHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALA 368
Query: 178 FKKDSK----GERHGSAAERLLAAQNP-LSQADRPHQLFADAPPPPSAPNPVVSSLGSGL 232
+K+ + ++ + NP L +P F A P P A + G G
Sbjct: 369 QRKEERKAILTNQYMQRLSTMRTLSNPLLGSFQQPSSYFLPAMPQPPAQ---AAYYGCGP 425
Query: 233 PPPGMPPP--GSFPPPVPPPGALPPGIPPAMPP 263
P P P S PP + P + P PP
Sbjct: 426 VTPTQPAPRWTSQPPRPSCASMVRPPVVPRRPP 458
Score = 77.4 bits (189), Expect = 2e-14
Identities = 53/186 (28%), Positives = 95/186 (51%), Gaps = 14/186 (7%)
Query: 15 VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIM 74
+++ L++ + L++ F G +++ + D + G+GFV F + E A AI M
Sbjct: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGSR--GFGFVHFETHEAAQQAINTM 158
Query: 75 NMIKLYGKPIRVNK-ASAHNKNLDVGA------NIFIGNLDPEIDEKLLYDTFSAFGVIL 127
N + L + + V S + ++GA NI++ NL ++DE+ L D FS FG +L
Sbjct: 159 NGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKML 218
Query: 128 QTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKGERH 187
K+MRD ++G+S+ + F+NF + + A+ MNG+ + R + YA + + ER
Sbjct: 219 SV-KVMRD-NSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGR---LLYAGRAQKRVERQ 273
Query: 188 GSAAER 193
R
Sbjct: 274 NELKRR 279
>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
Length = 382
Score = 110 bits (274), Expect = 3e-24
Identities = 69/175 (39%), Positives = 98/175 (56%), Gaps = 5/175 (2%)
Query: 13 ATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIK 72
A +YVG LD V+E +L++ F AGP+ T + +D VT GYG+V F DA++A+
Sbjct: 18 AALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALN 77
Query: 73 IMNMIKLYGKPIRVNKASAHNKNLDVG-ANIFIGNLDPEIDEKLLYDTFSAFGVILQTPK 131
MN + GKP R+ + ++ G NIFI NLD ID + L+ FSAFG IL
Sbjct: 78 TMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKV 137
Query: 132 IMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVS-YAFKKDSKGE 185
+ D SKGYA+++F S A++ AI MNG L NR + V + F ++ E
Sbjct: 138 VC---DDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAE 189
Score = 76.3 bits (186), Expect = 5e-14
Identities = 49/185 (26%), Positives = 94/185 (50%), Gaps = 21/185 (11%)
Query: 8 ERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDA 67
+R V+V + + + + L ELF + GP + + +D +G+ +G+GFV + + E A
Sbjct: 194 DRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRD-ASGKSKGFGFVRYETHEAA 252
Query: 68 DYAIKIMNMIKLYGKPIRVNKASAH-----------------NKNLDVGANIFIGNLDPE 110
A+ ++ + GK + V +A K+ G I+I NLD
Sbjct: 253 QKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDET 312
Query: 111 IDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNR 170
I+++ L + FS+FG I + +M + G KG+ + F+SF+ + A++ MNG+ + ++
Sbjct: 313 INDEKLKEEFSSFGSISRAKVMM---EVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSK 369
Query: 171 PITVS 175
P+ V+
Sbjct: 370 PLHVT 374
Score = 48.9 bits (115), Expect = 9e-06
Identities = 27/91 (29%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Query: 91 AHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFA 150
A K + A +++G+LDP++ E +LY F G L+ +I RDP T + GY ++NF
Sbjct: 9 AGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGP-LRFTRICRDPVTRSPLGYGYVNFR 67
Query: 151 SFDASDAAIEAMNGQYLCNRPITVSYAFKKD 181
++ A+ MN + +P + ++ D
Sbjct: 68 FPADAEWALNTMNFDLINGKPFRLMWSQPDD 98
Score = 38.1 bits (87), Expect = 0.015
Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
Query: 15 VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIM 74
+Y+ LDE +++ L E F G + + + GQ +G+G V F S E+A A+ M
Sbjct: 304 IYIKNLDETINDEKLKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEEATKAVDEM 361
Query: 75 NMIKLYGKPIRVNKASAHNK 94
N + KP+ V A +
Sbjct: 362 NGRIVGSKPLHVTLGQARRR 381
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 109 bits (273), Expect = 4e-24
Identities = 89/241 (36%), Positives = 96/241 (39%), Gaps = 45/241 (18%)
Query: 212 ADAPPP----PSAPNPVVSSLGSGLPP-----PGMPPPGSFPPPVPPPGALPPGIPPAMP 262
+ PPP P P P + G PP G PP G PPP PG P P
Sbjct: 68 SQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPR---PGKPEGPP 124
Query: 263 P--------PPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHH 314
P PP PG PP G G P P P P G P G +Q Q
Sbjct: 125 PQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPP------PRPGKPEGPPPQGGNQSQ---G 175
Query: 315 GPHGLGHPHAGPPGSGGQ---PPPRP-----PP---GMPHPGPPPMGMPPRGPPFGSPMG 363
P G P PP G Q PPPRP PP G GPPP P GPP
Sbjct: 176 PPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNK 235
Query: 364 HPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPV-PPRGPLRGPL 422
GP PPH G P PP P RPPP G +GP PPP P+ P+ PP G +GP
Sbjct: 236 PQGP-PPH--PGKPQGPPPQEGNKPQRPPPPGRPQGP-PPPGGNPQQPLPPPAGKPQGPP 291
Query: 423 P 423
P
Sbjct: 292 P 292
Score = 103 bits (256), Expect = 4e-22
Identities = 81/224 (36%), Positives = 89/224 (39%), Gaps = 47/224 (20%)
Query: 212 ADAPPP----PSAPNPVVSSLGSGLPP-----PGMPPPGSFPPPVPPPGALPPGIPPAMP 262
+ PPP P P P + G PP G PP G PPP PG P P
Sbjct: 110 SQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPR---PGKPEGPP 166
Query: 263 P--------PPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHH 314
P PP PG PP G G P P P P G P G +Q Q
Sbjct: 167 PQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPP------PRPGKPEGPPPQGGNQSQ---- 216
Query: 315 GPHGLGHPHAGPPGSGGQPPPRPPP--GMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHG 372
GP GPP GG P PPP G P PP G P+ PP P G P
Sbjct: 217 GPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPP---PPGRP------- 266
Query: 373 MRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRG 416
+GPP PP G P PPP G +GP PPP+ RP PP+G
Sbjct: 267 -QGPP---PPGGNPQQPLPPPAGKPQGPPPPPQ-GGRPHRPPQG 305
Score = 97.4 bits (241), Expect = 2e-20
Identities = 82/234 (35%), Positives = 90/234 (38%), Gaps = 47/234 (20%)
Query: 227 SLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPP-----AMPPPPMPPGAAGHGPPSAGTP 281
S+ SG P P G+ P PPP P G PP + PPP P G PP G
Sbjct: 30 SVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGP-PPQGGNQ 88
Query: 282 GAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPP--P 339
G P P P P G P G +Q Q GP GPP GG PP P
Sbjct: 89 SQGPP------PRPGKPEGQPPQGGNQSQ----GPPPRPGKPEGPPPQGGNQSQGPPPRP 138
Query: 340 GMPHPGPPPMGMPPRGPP--FGSPMGHP--------GPMP-PHGMRGPPPLMPPHGYTGP 388
G P PP G +GPP G P G P GP P P GPPP P
Sbjct: 139 GKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPP 198
Query: 389 PR------PPPYGYQRGPLPPPRP------------TPRPPVPPRGPLRGPLPQ 424
PR PPP G + PPPRP P+ P P G +GP PQ
Sbjct: 199 PRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQ 252
Score = 85.9 bits (211), Expect = 6e-17
Identities = 72/199 (36%), Positives = 77/199 (38%), Gaps = 40/199 (20%)
Query: 212 ADAPPP----PSAPNPVVSSLGSGLPP-----PGMPPPGSFPPPVPPPGALPPGIPPAMP 262
+ PPP P P P + G PP G PP G PPP PG P P
Sbjct: 131 SQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPH---PGKPEGPP 187
Query: 263 P--------PPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHH 314
P PP PG PP G G P P P P G P G ++ Q
Sbjct: 188 PQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPP------PRPGKPEGPPSQGGNKPQ---- 237
Query: 315 GPHGLGHPHAGPPGSGGQPPPR-PPPGMPHPGPPPMGMP--PRGPPFGSPMGHPGPMPPH 371
GP GPP G P R PPPG P PPP G P P PP G P G P PP
Sbjct: 238 GPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQG--PPPPPQ 295
Query: 372 GMRGPPPLMPPHGYTGPPR 390
G R P PP G PP+
Sbjct: 296 GGR---PHRPPQGQ--PPQ 309
Score = 55.1 bits (131), Expect = 1e-07
Identities = 49/168 (29%), Positives = 53/168 (31%), Gaps = 46/168 (27%)
Query: 202 SQADRPHQLFADAPPP---------------PSAPNPVVSSLGSGLPPPGMPPPGSFPPP 246
SQ PH + PPP P P P + G P P PG P
Sbjct: 173 SQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPP----PRPGKPEGP 228
Query: 247 VPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGM 306
G P G PP P PP G+ P PG P PPGG P
Sbjct: 229 PSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQ--------GPPPPGGNPQ--- 277
Query: 307 SQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPR 354
P P G PPP P G PH PP G PP+
Sbjct: 278 --------------QPLPPPAGKPQGPPPPPQGGRPH--RPPQGQPPQ 309
Score = 46.2 bits (108), Expect = 6e-05
Identities = 32/89 (35%), Positives = 35/89 (39%), Gaps = 11/89 (12%)
Query: 198 QNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMP----PPGSFPP-PVPPPGA 252
+ P SQ Q P P P P + PPPG P PPG P P+PPP
Sbjct: 226 EGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAG 285
Query: 253 LPPGIPPAMPPPPMPPGAAGHGPPSAGTP 281
P PPPP P G H PP P
Sbjct: 286 -----KPQGPPPP-PQGGRPHRPPQGQPP 308
Score = 30.4 bits (67), Expect = 3.2
Identities = 23/64 (35%), Positives = 25/64 (39%), Gaps = 17/64 (26%)
Query: 370 PHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPP--------VPPR-GPLRG 420
P + G P P G P R PP PP +P RPP PPR G G
Sbjct: 29 PSVISGKPEGRRPQGGNQPQRTPP--------PPGKPEGRPPQGGNQSQGPPPRPGKPEG 80
Query: 421 PLPQ 424
P PQ
Sbjct: 81 PPPQ 84
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 107 bits (268), Expect = 2e-23
Identities = 83/229 (36%), Positives = 99/229 (43%), Gaps = 33/229 (14%)
Query: 207 PHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAM---PP 263
P + + AP PP+ P P S G+ +PPP P + PPP PPP PP +P + P
Sbjct: 564 PPSVPSRAPVPPAPPLPGDS--GTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSP 621
Query: 264 PPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPG-GMPHPGMSQMQLAHHGPHGLGHP 322
P +P G A PP P P P P G G+P P P G P
Sbjct: 622 PSLPGGTAISPPPPLSGDATIPP------PPPLPEGVGIPSPSSL--------PGGTAIP 667
Query: 323 HAGP-PGSGGQPPPRPP----PGMPHPGPP---PMGMPPRGPPFGSPMGHPGPMPPHGMR 374
P PGS PPP PP G+P P PP GMPP PP G PG PP
Sbjct: 668 PPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLP---GGPGIPPPPPFP 724
Query: 375 GPPPLMPPHGYTGPPRPPPYGY--QRGPLPPPRPTPRPPVPPRGPLRGP 421
G P + PP G P PPP+G+ P+ P TP+ P LR P
Sbjct: 725 GGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLRRP 773
Score = 83.6 bits (205), Expect = 3e-16
Identities = 67/192 (34%), Positives = 75/192 (39%), Gaps = 21/192 (10%)
Query: 237 MPPPGSFPPPVPPPGALPPGIPPAMPPPPMP-PGAAGHGPPSAGTPGAGHPGHGHSHPHP 295
+PP PVPP LP +PPPP P PP P PG P
Sbjct: 563 VPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPP 622
Query: 296 FPPGGM------PHPGMSQMQLAHHGPHGLGHPH-AGPPGSGGQPPPRPPPGMPHPGPPP 348
PGG P G + + P G+G P + PG PPP P PG PPP
Sbjct: 623 SLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP 682
Query: 349 MGMPPRGPPFGSPMGHPGPMPP----HGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPP 404
PP G P P PP GM PPP +P G G P PPP+ G PPP
Sbjct: 683 -------PPLPGSAGIPPPPPPLPGEAGMPPPPPPLP--GGPGIPPPPPFPGGPGIPPPP 733
Query: 405 RPTPRPPVPPRG 416
PP PP G
Sbjct: 734 PGMGMPPPPPFG 745
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 107 bits (268), Expect = 2e-23
Identities = 83/229 (36%), Positives = 99/229 (43%), Gaps = 33/229 (14%)
Query: 207 PHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAM---PP 263
P + + AP PP+ P P S G+ +PPP P + PPP PPP PP +P + P
Sbjct: 573 PPSVPSRAPVPPAPPLPGDS--GTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSP 630
Query: 264 PPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPG-GMPHPGMSQMQLAHHGPHGLGHP 322
P +P G A PP P P P P G G+P P P G P
Sbjct: 631 PSLPGGTAISPPPPLSGDATIPP------PPPLPEGVGIPSPSSL--------PGGTAIP 676
Query: 323 HAGP-PGSGGQPPPRPP----PGMPHPGPP---PMGMPPRGPPFGSPMGHPGPMPPHGMR 374
P PGS PPP PP G+P P PP GMPP PP G PG PP
Sbjct: 677 PPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLP---GGPGIPPPPPFP 733
Query: 375 GPPPLMPPHGYTGPPRPPPYGY--QRGPLPPPRPTPRPPVPPRGPLRGP 421
G P + PP G P PPP+G+ P+ P TP+ P LR P
Sbjct: 734 GGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLRRP 782
Score = 83.6 bits (205), Expect = 3e-16
Identities = 67/192 (34%), Positives = 75/192 (39%), Gaps = 21/192 (10%)
Query: 237 MPPPGSFPPPVPPPGALPPGIPPAMPPPPMP-PGAAGHGPPSAGTPGAGHPGHGHSHPHP 295
+PP PVPP LP +PPPP P PP P PG P
Sbjct: 572 VPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPP 631
Query: 296 FPPGGM------PHPGMSQMQLAHHGPHGLGHPH-AGPPGSGGQPPPRPPPGMPHPGPPP 348
PGG P G + + P G+G P + PG PPP P PG PPP
Sbjct: 632 SLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP 691
Query: 349 MGMPPRGPPFGSPMGHPGPMPP----HGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPP 404
PP G P P PP GM PPP +P G G P PPP+ G PPP
Sbjct: 692 -------PPLPGSAGIPPPPPPLPGEAGMPPPPPPLP--GGPGIPPPPPFPGGPGIPPPP 742
Query: 405 RPTPRPPVPPRG 416
PP PP G
Sbjct: 743 PGMGMPPPPPFG 754
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 106 bits (264), Expect = 5e-23
Identities = 85/231 (36%), Positives = 96/231 (41%), Gaps = 55/231 (23%)
Query: 181 DSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPP 240
DS+ E+ + + + S A Q APP P+ + + G PP G PP
Sbjct: 363 DSEAEKQSQKQHKEESHSDGTSTASSQQQ----APPQSVPPSQIQAPPMPGPPPLGPPPA 418
Query: 241 GSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGG 300
PP PP G LPPG PP PP PPG G P P PPG
Sbjct: 419 PPLRPPGPPTG-LPPGPPPGAPPFLRPPGMPGLRGPL---------------PRLLPPG- 461
Query: 301 MPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGS 360
P PG PPG PPP PPPG+P PGPPP G PPR PP +
Sbjct: 462 -PPPGR-------------------PPG----PPPGPPPGLP-PGPPPRGPPPRLPP-PA 495
Query: 361 PMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPP 411
P G P P P GM PPL+PP G P PP PLP P PP
Sbjct: 496 PPGIPPPRP--GMM-RPPLVPPLGPAPPGLFPP-----APLPNPGVLSAPP 538
Score = 84.7 bits (208), Expect = 1e-16
Identities = 71/181 (39%), Positives = 77/181 (42%), Gaps = 52/181 (28%)
Query: 252 ALPPGIPPA-MPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQ 310
A P +PP+ + PPMP GPP G P P PP P P
Sbjct: 392 APPQSVPPSQIQAPPMP------GPPPLGPP-------------PAPPLRPPGP------ 426
Query: 311 LAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMP----------HPGPPPMGMPPRGPPFGS 360
P GL P PPG+ PP PPGMP PGPPP G PP GPP G
Sbjct: 427 -----PTGL--PPGPPPGA---PPFLRPPGMPGLRGPLPRLLPPGPPP-GRPP-GPPPGP 474
Query: 361 PMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRG 420
P G P PP RGPPP +PP G P P P G R PL PP P + P PL
Sbjct: 475 PPGLPPGPPP---RGPPPRLPPPAPPGIPPPRP-GMMRPPLVPPLGPAPPGLFPPAPLPN 530
Query: 421 P 421
P
Sbjct: 531 P 531
Score = 82.4 bits (202), Expect = 7e-16
Identities = 76/200 (38%), Positives = 80/200 (40%), Gaps = 82/200 (41%)
Query: 233 PPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSH 292
PP +PP PP+P P L P PPA PP PPG P G P
Sbjct: 393 PPQSVPPSQIQAPPMPGPPPLGP--PPA--PPLRPPG------PPTGLP----------- 431
Query: 293 PHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQP-------PPRPPPGMPHPG 345
P PP G P P PPG G PP PPPG P PG
Sbjct: 432 --PGPPPGAP-------------------PFLRPPGMPGLRGPLPRLLPPGPPPGRP-PG 469
Query: 346 PPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPR 405
PPP GPP G P PGP P RGPPP +PP P PP +PPPR
Sbjct: 470 PPP------GPPPGLP---PGPPP----RGPPPRLPP------PAPPG-------IPPPR 503
Query: 406 P-TPRPP-VPPRGPLRGPLP 423
P RPP VPP GP P
Sbjct: 504 PGMMRPPLVPP----LGPAP 519
Score = 70.9 bits (172), Expect = 2e-12
Identities = 44/105 (41%), Positives = 49/105 (46%), Gaps = 20/105 (19%)
Query: 333 PPPRPPPGM----PHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTG- 387
PP PP P PGPPP+G PP PP P G P +PP G PP + P G G
Sbjct: 393 PPQSVPPSQIQAPPMPGPPPLGPPP-APPLRPP-GPPTGLPPGPPPGAPPFLRPPGMPGL 450
Query: 388 --------PPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRGPLPQ 424
PP PPP G P P P P P +PP P RGP P+
Sbjct: 451 RGPLPRLLPPGPPP-----GRPPGPPPGPPPGLPPGPPPRGPPPR 490
Score = 47.0 bits (110), Expect = 3e-05
Identities = 29/69 (42%), Positives = 33/69 (47%), Gaps = 9/69 (13%)
Query: 215 PPPPSAPNPVVSSLGSGLPPP---GMPP--PGSFPPP-VPPPGALPPGIPPAMPPPPMPP 268
PPP P P LPPP G+PP PG PP VPP G PPG+ PP P+P
Sbjct: 474 PPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGL---FPPAPLPN 530
Query: 269 GAAGHGPPS 277
PP+
Sbjct: 531 PGVLSAPPN 539
Score = 39.3 bits (90), Expect = 0.007
Identities = 25/66 (37%), Positives = 28/66 (42%), Gaps = 15/66 (22%)
Query: 374 RGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPR----PTPRPPVPPRGP-----------L 418
+ PP +PP PP P P P PP R PT PP PP G L
Sbjct: 391 QAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGL 450
Query: 419 RGPLPQ 424
RGPLP+
Sbjct: 451 RGPLPR 456
Score = 37.0 bits (84), Expect = 0.034
Identities = 26/71 (36%), Positives = 32/71 (45%), Gaps = 9/71 (12%)
Query: 190 AAERLLAAQNPLSQADRPHQLF-ADAPPPPSAPNPVVSSLGSGLP--PPGMPPPGSFPPP 246
A +L PL A P L A PP+ ++ LG G+P PPG PPG
Sbjct: 147 APSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPG----- 201
Query: 247 VPPPGALPPGI 257
PPPG PP +
Sbjct: 202 -PPPGPPPPQV 211
Score = 36.6 bits (83), Expect = 0.044
Identities = 28/103 (27%), Positives = 39/103 (37%), Gaps = 9/103 (8%)
Query: 170 RPITVSYAFKKDSKGERHGSAAERLLAAQNPLSQADRPHQ----LFADAPPPPSAPNPVV 225
R + V Y K+ + + + D PH L D P P + P ++
Sbjct: 108 RKLEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSIL 167
Query: 226 SSLGSGLPPPG----MPPPGSFPPPVPPPGALPPGIPPAMPPP 264
+ PP +P G P +PP G PPG PP PPP
Sbjct: 168 KKTSAYGPPTRAVSILPLLGHGVPRLPP-GRKPPGPPPGPPPP 209
Score = 34.7 bits (78), Expect = 0.17
Identities = 21/66 (31%), Positives = 27/66 (40%), Gaps = 12/66 (18%)
Query: 216 PPPSAPNPVVSSLGSGLPPPGMPPPG------SFPPPVPPPGALP------PGIPPAMPP 263
P P P+ + L +P PG PP ++ PP LP P +PP P
Sbjct: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKP 199
Query: 264 PPMPPG 269
P PPG
Sbjct: 200 PGPPPG 205
Score = 33.1 bits (74), Expect = 0.49
Identities = 17/41 (41%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 331 GQPPPRPPPGMPHPGPPPMGMPPR-GPPFGSPMGHPGPMPP 370
G PR PPG PGPPP PP+ +G +G +PP
Sbjct: 187 GHGVPRLPPGRKPPGPPPGPPPPQVVQMYGRKVGFALDLPP 227
Score = 32.3 bits (72), Expect = 0.84
Identities = 26/85 (30%), Positives = 32/85 (37%), Gaps = 16/85 (18%)
Query: 232 LPPPGMP--PPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTP-----GAG 284
+P P MP P +P PGA PP I + +GPP+ G G
Sbjct: 139 IPLPDMPHAPSNILIQDIPLPGAQPPSILKK---------TSAYGPPTRAVSILPLLGHG 189
Query: 285 HPGHGHSHPHPFPPGGMPHPGMSQM 309
P P PP G P P + QM
Sbjct: 190 VPRLPPGRKPPGPPPGPPPPQVVQM 214
Score = 29.3 bits (64), Expect = 7.1
Identities = 28/86 (32%), Positives = 35/86 (40%), Gaps = 25/86 (29%)
Query: 337 PPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMR-----GPPP----LMPPHGYTG 387
P P MPH P + + P PG PP ++ GPP ++P G+ G
Sbjct: 140 PLPDMPHA---PSNILIQDIPL------PGAQPPSILKKTSAYGPPTRAVSILPLLGH-G 189
Query: 388 PPRPPPYGYQRGPLPPPRPTPRPPVP 413
PR PP PP P P PP P
Sbjct: 190 VPRLPP------GRKPPGPPPGPPPP 209
>gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Homo
sapiens]
Length = 200
Score = 105 bits (261), Expect = 1e-22
Identities = 62/177 (35%), Positives = 101/177 (57%), Gaps = 7/177 (3%)
Query: 13 ATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIK 72
A++YVG L +V+E +L+E F AGP+++ + +D++T + GY +V + DA A++
Sbjct: 2 ASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALE 61
Query: 73 IMNMIKLYGKPIRV--NKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTP 130
+N + G+P+R+ ++ + VG N+FI NL ID K LY+ FSAFG IL
Sbjct: 62 TLNFDVIKGRPVRIMWSQRDPSLRKSGVG-NVFIKNLGKTIDNKALYNIFSAFGNILSCK 120
Query: 131 KIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVS-YAFKKDSKGER 186
D KGY F++F ++++ AI+ MNG +L R I V + K+ + ER
Sbjct: 121 VAC---DEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAER 174
>gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo
sapiens]
Length = 200
Score = 105 bits (261), Expect = 1e-22
Identities = 62/177 (35%), Positives = 101/177 (57%), Gaps = 7/177 (3%)
Query: 13 ATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIK 72
A++YVG L +V+E +L+E F AGP+++ + +D++T + GY +V + DA A++
Sbjct: 2 ASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALE 61
Query: 73 IMNMIKLYGKPIRV--NKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTP 130
+N + G+P+R+ ++ + VG N+FI NL ID K LY+ FSAFG IL
Sbjct: 62 TLNFDVIKGRPVRIMWSQRDPSLRKSGVG-NVFIKNLGKTIDNKALYNIFSAFGNILSCK 120
Query: 131 KIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVS-YAFKKDSKGER 186
D KGY F++F ++++ AI+ MNG +L R I V + K+ + ER
Sbjct: 121 VAC---DEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAER 174
>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
sapiens]
Length = 247
Score = 104 bits (260), Expect = 1e-22
Identities = 75/207 (36%), Positives = 82/207 (39%), Gaps = 30/207 (14%)
Query: 234 PPGMPPPGSFPPPVPPPGALPPGIPPAMPP--------PPMPPGAAGHGPPSAGTPGAGH 285
P G P G P PPP PPG P PP PP PPG PP G G
Sbjct: 36 PEGRRPQGGNQPQRPPP---PPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGP 92
Query: 286 PGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQP-PPRPPPGMPHP 344
P PHP P P G +Q Q P G P PP G Q P PPPG P
Sbjct: 93 P------PHPGKPERPPPQGGNQSQGTPPPP---GKPERPPPQGGNQSHRPPPPPGKPER 143
Query: 345 GPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPR--------PPPYGY 396
PP G +GPP P GP P G + PP GPP+ PPP G
Sbjct: 144 PPPQGGNQSQGPP-PHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGK 202
Query: 397 QRGPLPPPRPTPRPPVPPRGPLRGPLP 423
+GP P +P PP G +GP P
Sbjct: 203 PQGPPPAGGNPQQPQAPPAGKPQGPPP 229
Score = 99.4 bits (246), Expect = 6e-21
Identities = 80/217 (36%), Positives = 88/217 (40%), Gaps = 40/217 (18%)
Query: 215 PPPPSAPNPVVSSLGSGLPPP--GMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAG 272
PPPP P PPP G G PPP P G P G + PPP PG
Sbjct: 51 PPPPGKPQG---------PPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPP-HPGKPE 100
Query: 273 HGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQ 332
PP G G P P P P P G +Q +H P G P PP G Q
Sbjct: 101 RPPPQGGNQSQGTP------PPPGKPERPPPQGGNQ---SHRPPPPPGKPERPPPQGGNQ 151
Query: 333 PP-PRPPPGMPHPGPPPM----GMPPRGPPFGSPMGHP--------GPMPPHGMRGPPPL 379
P P PG P GPPP R PP G P G P GP PP +GPP
Sbjct: 152 SQGPPPHPGKPE-GPPPQEGNKSRSARSPP-GKPQGPPQQEGNKPQGPPPPGKPQGPP-- 207
Query: 380 MPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRG 416
P G P+ PP G +GP PPP+ RPP P +G
Sbjct: 208 -PAGGNPQQPQAPPAGKPQGPPPPPQ-GGRPPRPAQG 242
Score = 75.5 bits (184), Expect = 9e-14
Identities = 66/189 (34%), Positives = 72/189 (38%), Gaps = 41/189 (21%)
Query: 215 PPPPSAPN---PVVSSLGSGLPP----PGMPPP-------GSFPPPVPPPGALPPGIPPA 260
PPPP P P + G PP P PPP G+ PPP P P G +
Sbjct: 72 PPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQS 131
Query: 261 MPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFP-----------PGGMPHPGMSQM 309
PPP PPG PP G G P H P P P G P Q
Sbjct: 132 HRPPP-PPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQE 190
Query: 310 QLAHHGPHGLGHPHAGPPGSGGQP--PPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGP 367
GP G P GPP +GG P P PP G P GPPP PP+G G P P
Sbjct: 191 GNKPQGPPPPGKPQ-GPPPAGGNPQQPQAPPAGKP-QGPPP---PPQG-------GRP-P 237
Query: 368 MPPHGMRGP 376
P G + P
Sbjct: 238 RPAQGQQPP 246
Score = 68.9 bits (167), Expect = 8e-12
Identities = 50/120 (41%), Positives = 54/120 (45%), Gaps = 26/120 (21%)
Query: 320 GHPHAGPPGSGGQPP-PRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHG---MRG 375
G P P G QP P PPPG P PP G +GPP P G P PP G +G
Sbjct: 34 GKPEGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPP--PPPGKPEGRPPQGGNQSQG 91
Query: 376 PPPLMPPHGYTG-PPRPPPYG--YQRGPLPPP----RPTP-------RPPVPPRGPLRGP 421
PPP + G P RPPP G +G PPP RP P RPP PP P R P
Sbjct: 92 PPP------HPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPP 145
Score = 42.4 bits (98), Expect = 8e-04
Identities = 34/99 (34%), Positives = 38/99 (38%), Gaps = 16/99 (16%)
Query: 202 SQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMP--PP---GSFPPPVPPPGALPPG 256
SQ PH + PPP + S PPG P PP G+ P PPPG P G
Sbjct: 152 SQGPPPHPGKPEGPPPQEG-----NKSRSARSPPGKPQGPPQQEGNKPQGPPPPGK-PQG 205
Query: 257 IPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHP 295
PPA P P PP+ G P G P P
Sbjct: 206 PPPAGGNPQQP-----QAPPAGKPQGPPPPPQGGRPPRP 239
Score = 32.3 bits (72), Expect = 0.84
Identities = 20/51 (39%), Positives = 22/51 (43%), Gaps = 1/51 (1%)
Query: 375 GPPPLMPPHGYTGPPRPPPY-GYQRGPLPPPRPTPRPPVPPRGPLRGPLPQ 424
G P P G P RPPP G +GP P + P PP G G PQ
Sbjct: 34 GKPEGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQ 84
>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
Length = 375
Score = 100 bits (250), Expect = 2e-21
Identities = 64/176 (36%), Positives = 96/176 (54%), Gaps = 6/176 (3%)
Query: 8 ERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDA 67
E T+YVG L V+E L+ +LF Q GP N M D T + Y FVEF A
Sbjct: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHA 59
Query: 68 DYAIKIMNMIKLYGKPIRVNKA---SAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFG 124
A+ MN K+ GK ++VN A S+ K+ ++F+G+L PEI + + F+ FG
Sbjct: 60 AAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFG 119
Query: 125 VILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKK 180
I ++++D TG SKGY F++F + ++ AI+ M GQ+L R I ++A +K
Sbjct: 120 RISDA-RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 174
Score = 70.9 bits (172), Expect = 2e-12
Identities = 53/187 (28%), Positives = 89/187 (47%), Gaps = 31/187 (16%)
Query: 2 AAGPISERNQDAT---VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGF 58
A P S++ + V+VG L +++ + F G + + + KD TG+ +GYGF
Sbjct: 81 ATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGF 140
Query: 59 VEFLSEEDADYAIKIMNMIKLYGKPIRVNKASAH---------------------NKNLD 97
V F ++ DA+ AI+ M L G+ IR N A+ N++
Sbjct: 141 VSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSP 200
Query: 98 VGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDA 157
++ G + + E+L+ TFS FG I++ I PD KGY+F+ F S +++
Sbjct: 201 SNCTVYCGGVTSGLTEQLMRQTFSPFGQIME---IRVFPD----KGYSFVRFNSHESAAH 253
Query: 158 AIEAMNG 164
AI ++NG
Sbjct: 254 AIVSVNG 260
Score = 45.8 bits (107), Expect = 7e-05
Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 8/91 (8%)
Query: 102 IFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEA 161
+++GNL ++ E L+ FS G IM DT + Y F+ F + AA+ A
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIM---DTAGNDPYCFVEFHEHRHAAAALAA 65
Query: 162 MNGQYLCNRPITVSYAF-----KKDSKGERH 187
MNG+ + + + V++A KKD+ H
Sbjct: 66 MNGRKIMGKEVKVNWATTPSSQKKDTSNHFH 96
>gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]
Length = 375
Score = 100 bits (248), Expect = 3e-21
Identities = 62/178 (34%), Positives = 98/178 (55%), Gaps = 6/178 (3%)
Query: 6 ISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEE 65
+ + Q T+YVG L V+E L+ +LF Q GP + M + + + Y FVEF
Sbjct: 2 MEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTS--NDPYCFVEFYEHR 59
Query: 66 DADYAIKIMNMIKLYGKPIRVNKA---SAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSA 122
DA A+ MN K+ GK ++VN A S+ K+ ++F+G+L PEI + + F+
Sbjct: 60 DAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAP 119
Query: 123 FGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKK 180
FG I ++++D TG SKGY F++F + ++ AI M GQ+L R I ++A +K
Sbjct: 120 FGKISDA-RVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRK 176
Score = 67.4 bits (163), Expect = 2e-11
Identities = 50/187 (26%), Positives = 89/187 (47%), Gaps = 31/187 (16%)
Query: 2 AAGPISERNQDAT---VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGF 58
A P S++ + V+VG L +++ + F G + + + KD TG+ +GYGF
Sbjct: 83 ATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGF 142
Query: 59 VEFLSEEDADYAIKIMNMIKLYGKPIRVNKASAH---------------------NKNLD 97
V F ++ DA+ AI M L G+ IR N A+ N++
Sbjct: 143 VSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSP 202
Query: 98 VGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDA 157
++ G + + ++L+ TFS FG I++ I P+ KGY+F+ F++ +++
Sbjct: 203 KNCTVYCGGIASGLTDQLMRQTFSPFGQIME---IRVFPE----KGYSFVRFSTHESAAH 255
Query: 158 AIEAMNG 164
AI ++NG
Sbjct: 256 AIVSVNG 262
Score = 38.9 bits (89), Expect = 0.009
Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 8/91 (8%)
Query: 102 IFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEA 161
+++GNL ++ E L+ FS G I T N Y F+ F + AA+ A
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEH--TSNDP-YCFVEFYEHRDAAAALAA 67
Query: 162 MNGQYLCNRPITVSYAF-----KKDSKGERH 187
MNG+ + + + V++A KKD+ H
Sbjct: 68 MNGRKILGKEVKVNWATTPSSQKKDTSNHFH 98
Score = 28.9 bits (63), Expect = 9.2
Identities = 20/59 (33%), Positives = 24/59 (40%), Gaps = 4/59 (6%)
Query: 329 SGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTG 387
+G Q PP G P G P + MG G PP G PPP++PP G
Sbjct: 312 NGWQVPPYGVYGQPWN---QQGFGVDQSPSAAWMGGFGAQPPQGQA-PPPVIPPPNQAG 366
>gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]
Length = 548
Score = 99.0 bits (245), Expect = 7e-21
Identities = 77/216 (35%), Positives = 86/216 (39%), Gaps = 25/216 (11%)
Query: 224 VVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGT-PG 282
+++ LG P P S P P A P P PPPP PP + P
Sbjct: 316 LMAELGEA-PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPS 374
Query: 283 AGHPGHGHSHPHPFPPGGMPH--PGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPG 340
P HG P PGG PH P HG H + H GPP QPPP P
Sbjct: 375 ESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQ 434
Query: 341 MPHP----GPPPMGMPPRGPPFGSPMG--HPG----PMPPHGMRGPPPLMPPHGYTGPPR 390
PHP GPPPM P GS + H G P PP GM PPP P +G P
Sbjct: 435 GPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPP----SGQPP 490
Query: 391 PPPYGYQRGPLPP---PRPTPRPPVPPRGPLRGPLP 423
PPP GPLPP + P PP PP + P
Sbjct: 491 PPP----SGPLPPWQQQQQQPPPPPPPSSSMASSTP 522
Score = 65.1 bits (157), Expect = 1e-10
Identities = 64/208 (30%), Positives = 70/208 (33%), Gaps = 54/208 (25%)
Query: 197 AQNPLSQADRPHQLFADAPPP----------------PSAPNPVVSSLGSGLPPPGMPPP 240
A PL+ A RP + PPP PS P G G PG P
Sbjct: 336 ATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPG-GGP 394
Query: 241 GSFPPPVP---------PPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHS 291
SFP P+P P P G PP PP PP G PP GH
Sbjct: 395 HSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPP------------GHH 442
Query: 292 HPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMG- 350
P P P S + H G + PP G PPP PPP P PPP G
Sbjct: 443 GPPPMDQYLGSTPVGSGVYRLHQGKGMMP-----PPPMGMMPPPPPPPS-GQPPPPPSGP 496
Query: 351 ---------MPPRGPPFGSPMGHPGPMP 369
PP PP S M P+P
Sbjct: 497 LPPWQQQQQQPPPPPPPSSSMASSTPLP 524
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 99.0 bits (245), Expect = 7e-21
Identities = 77/216 (35%), Positives = 86/216 (39%), Gaps = 25/216 (11%)
Query: 224 VVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGT-PG 282
+++ LG P P S P P A P P PPPP PP + P
Sbjct: 316 LMAELGEA-PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPS 374
Query: 283 AGHPGHGHSHPHPFPPGGMPH--PGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPG 340
P HG P PGG PH P HG H + H GPP QPPP P
Sbjct: 375 ESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQ 434
Query: 341 MPHP----GPPPMGMPPRGPPFGSPMG--HPG----PMPPHGMRGPPPLMPPHGYTGPPR 390
PHP GPPPM P GS + H G P PP GM PPP P +G P
Sbjct: 435 GPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPP----SGQPP 490
Query: 391 PPPYGYQRGPLPP---PRPTPRPPVPPRGPLRGPLP 423
PPP GPLPP + P PP PP + P
Sbjct: 491 PPP----SGPLPPWQQQQQQPPPPPPPSSSMASSTP 522
Score = 74.7 bits (182), Expect = 1e-13
Identities = 88/297 (29%), Positives = 99/297 (33%), Gaps = 108/297 (36%)
Query: 197 AQNPLSQADRPHQLFADAPPP----------------PSAPNPVVSSLGSGLPPPGMPPP 240
A PL+ A RP + PPP PS P G G PG P
Sbjct: 336 ATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPG-GGP 394
Query: 241 GSFPPPVP--------------PPGALPPGIPPAMPPPPM-----PPGAAGHGPPS---- 277
SFP P+P P G PP + P PPPPM PPG HGPP
Sbjct: 395 HSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQP--PPPPMNQGPHPPGH--HGPPPMDQY 450
Query: 278 -AGTP-GAG----HPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGG 331
TP G+G H G G P P G MP P PP G
Sbjct: 451 LGSTPVGSGVYRLHQGKGMMPPPPM--GMMPPP---------------------PPPPSG 487
Query: 332 QPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMP---------------------- 369
QPPP PP G P PP PP S M P+P
Sbjct: 488 QPPP-PPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQ 546
Query: 370 ----------PHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRG 416
M+G P ++P PP PP G P PPP + +PPRG
Sbjct: 547 QQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPP--GAPPPPPPPPPGSAGMMIPPRG 601
Score = 70.5 bits (171), Expect = 3e-12
Identities = 62/187 (33%), Positives = 69/187 (36%), Gaps = 30/187 (16%)
Query: 206 RPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPP 265
R HQ PPPP G+ PP PPP PPP PP G LPP PPP
Sbjct: 462 RLHQGKGMMPPPPM-----------GMMPPPPPPPSGQPPP-PPSGPLPPWQQQQQQPPP 509
Query: 266 MPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLA----HHGPHGLGH 321
PP P S+ P ++ G P Q Q A P G+
Sbjct: 510 PPP------PSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGN 563
Query: 322 PHAGPPGSGGQPPPRPPPGMPHPGPPP------MGMPPRGPPFGSPMGHPGPMPPHGMRG 375
P P G QPP PPG P P PPP M +PPRG S P P + G
Sbjct: 564 PTMVPLPPGVQPP--LPPGAPPPPPPPPPGSAGMMIPPRGGDGPSHESEDFPRPLVTLPG 621
Query: 376 PPPLMPP 382
P P
Sbjct: 622 RQPQQRP 628
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 99.0 bits (245), Expect = 7e-21
Identities = 77/216 (35%), Positives = 86/216 (39%), Gaps = 25/216 (11%)
Query: 224 VVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGT-PG 282
+++ LG P P S P P A P P PPPP PP + P
Sbjct: 316 LMAELGEA-PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPS 374
Query: 283 AGHPGHGHSHPHPFPPGGMPH--PGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPG 340
P HG P PGG PH P HG H + H GPP QPPP P
Sbjct: 375 ESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQ 434
Query: 341 MPHP----GPPPMGMPPRGPPFGSPMG--HPG----PMPPHGMRGPPPLMPPHGYTGPPR 390
PHP GPPPM P GS + H G P PP GM PPP P +G P
Sbjct: 435 GPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPP----SGQPP 490
Query: 391 PPPYGYQRGPLPP---PRPTPRPPVPPRGPLRGPLP 423
PPP GPLPP + P PP PP + P
Sbjct: 491 PPP----SGPLPPWQQQQQQPPPPPPPSSSMASSTP 522
Score = 84.0 bits (206), Expect = 2e-16
Identities = 70/207 (33%), Positives = 80/207 (38%), Gaps = 40/207 (19%)
Query: 206 RPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPP 265
R HQ PPPP G+ PP PPP PPP PP G LPP PPP
Sbjct: 462 RLHQGKGMMPPPPM-----------GMMPPPPPPPSGQPPP-PPSGPLPPWQQQQQQPPP 509
Query: 266 MPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLA----HHGPHGLGH 321
PP P S+ P ++ G P Q Q A P G+
Sbjct: 510 PPP------PSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGN 563
Query: 322 PHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMP 381
P P G QPP PPG P P PPP PP + M + P PP PPP+ P
Sbjct: 564 PTMVPLPPGVQPP--LPPGAPPPPPPP-------PPGSAGMMYAPPPPP-----PPPMDP 609
Query: 382 PHGYT----GPPRPPPYGYQRGPLPPP 404
+ T G PP+G P PPP
Sbjct: 610 SNFVTMMGMGVAGMPPFGMPPAPPPPP 636
Score = 74.7 bits (182), Expect = 1e-13
Identities = 74/222 (33%), Positives = 83/222 (37%), Gaps = 67/222 (30%)
Query: 200 PLSQADRPHQLFADAPPPPS---APNPVVSSL-----GSGLPPPGMPPPGSFPPPVPPPG 251
P++Q PH PPP PV S + G G+ PP PP G PPP PPP
Sbjct: 431 PMNQG--PHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPP--PPMGMMPPPPPPPS 486
Query: 252 ALPPG-----IPP-----AMPPPPMPPGA--------------------AGHG--PP--- 276
PP +PP PPPP PP + AG G PP
Sbjct: 487 GQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQ 546
Query: 277 ----SAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQ 332
+A +PGA G+ P PPG P P P PPGS G
Sbjct: 547 QQAAAAASPGAPQM-QGNPTMVPLPPGVQPPLP----------PGAPPPPPPPPPGSAGM 595
Query: 333 ----PPPRPPPGMPHPGPPPMGMPPRG-PPFGSPMGHPGPMP 369
PPP PPP P MGM G PPFG P P P P
Sbjct: 596 MYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPPP 637
Score = 73.2 bits (178), Expect = 4e-13
Identities = 88/297 (29%), Positives = 100/297 (33%), Gaps = 102/297 (34%)
Query: 197 AQNPLSQADRPHQLFADAPPP----------------PSAPNPVVSSLGSGLPPPGMPPP 240
A PL+ A RP + PPP PS P G G PG P
Sbjct: 336 ATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPG-GGP 394
Query: 241 GSFPPPVP--------------PPGALPPGIPPAMPPPPM-----PPGAAGHGPPS---- 277
SFP P+P P G PP + P PPPPM PPG HGPP
Sbjct: 395 HSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQP--PPPPMNQGPHPPGH--HGPPPMDQY 450
Query: 278 -AGTP-GAG----HPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPG--- 328
TP G+G H G G P P G MP P P G P P G
Sbjct: 451 LGSTPVGSGVYRLHQGKGMMPPPPM--GMMPPPP----------PPPSGQPPPPPSGPLP 498
Query: 329 ----SGGQPPPRPPPGMPHPGPPPM----------------GMPPRGPPFGSPMGHPG-- 366
QPPP PPP P+ +PP + PG
Sbjct: 499 PWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAP 558
Query: 367 ---------PMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPP 414
P+PP G P +PP PP PPP G + P P P PP+ P
Sbjct: 559 QMQGNPTMVPLPP----GVQPPLPPGAPPPPPPPPP--GSAGMMYAPPPPPPPPMDP 609
>gi|21389357 MAPK-interacting and spindle-stabilizing protein [Homo
sapiens]
Length = 245
Score = 98.6 bits (244), Expect = 9e-21
Identities = 79/212 (37%), Positives = 88/212 (41%), Gaps = 27/212 (12%)
Query: 218 PSAPNPVVSSLGSGLPPPGMPPPGSF-PPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPP 276
PSAP SS+ SGLPP P F P P ++PP PP PP P PP PP
Sbjct: 43 PSAP----SSVPSGLPPSATPSTVPFGPAPTGMYPSVPPTGPPPGPPAPFPPSGPSCPPP 98
Query: 277 SAGTPGAGHPGHGHSHPHP---FPPGGMPHPGMSQMQLAHHGPHG-LGHPHAGP--PGSG 330
P PG G + P+P P +P P + A GP G G +GP PG G
Sbjct: 99 GGPYPAPTVPGPGPTGPYPTPNMPFPELPRPYGAPTDPAAAGPLGPWGSMSSGPWAPGMG 158
Query: 331 GQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPR 390
GQ P P MP+P P P PP P PG PP PP G GPP
Sbjct: 159 GQ---YPTPNMPYPSPGPYPAPP-------PPQAPGAAPPVPWGTVPP-----GAWGPPA 203
Query: 391 PPPYGYQRGPLPPPRPTPRPPVP-PRGPLRGP 421
P P P P PTP P P GP P
Sbjct: 204 PYPAPTGSYPTPGLYPTPSNPFQVPSGPSGAP 235
Score = 69.3 bits (168), Expect = 6e-12
Identities = 63/171 (36%), Positives = 68/171 (39%), Gaps = 23/171 (13%)
Query: 216 PPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMP-------- 267
PPP P P S G PPPG P P P VP PG P P MP P +P
Sbjct: 80 PPPGPPAPFPPS-GPSCPPPGGPYPA---PTVPGPGPTGPYPTPNMPFPELPRPYGAPTD 135
Query: 268 PGAAGH-GPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAG- 325
P AAG GP + + G PG G +P P P P PG P G
Sbjct: 136 PAAAGPLGPWGSMSSGPWAPGMGGQYPTPNMP--YPSPGPYPAPPPPQAPGAAPPVPWGT 193
Query: 326 -PPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPG--PMP--PH 371
PPG+ G PP P P P P P PF P G G PMP PH
Sbjct: 194 VPPGAWG--PPAPYPAPTGSYPTPGLYPTPSNPFQVPSGPSGAPPMPGGPH 242
Score = 63.5 bits (153), Expect = 3e-10
Identities = 48/152 (31%), Positives = 53/152 (34%), Gaps = 28/152 (18%)
Query: 273 HGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQ 332
H P PG PP G P G + +P A G
Sbjct: 14 HSPAKTSAVSNTKPGQ--------PPQGWP------------GSNPWNNPSAPSSVPSGL 53
Query: 333 PPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPP-------PLMPPHGY 385
PP P +P GP P GM P PP G P G P P PP G PP P +P G
Sbjct: 54 PPSATPSTVPF-GPAPTGMYPSVPPTGPPPGPPAPFPPSGPSCPPPGGPYPAPTVPGPGP 112
Query: 386 TGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGP 417
TGP P + P P PT P GP
Sbjct: 113 TGPYPTPNMPFPELPRPYGAPTDPAAAGPLGP 144
Score = 60.8 bits (146), Expect = 2e-09
Identities = 62/203 (30%), Positives = 73/203 (35%), Gaps = 35/203 (17%)
Query: 252 ALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQL 311
+L +P P G P G PG+ +P + S P P G P S +
Sbjct: 6 SLADALPEHSPAKTSAVSNTKPGQPPQGWPGS-NPWNNPSAPSSVPSGLPPSATPSTVPF 64
Query: 312 AHHGPHGL--GHPHAGPPGSGGQPPPR-------PPPGMPHPGPPPMGMPPRGP------ 356
P G+ P GPP G P P PPPG P+P P G P GP
Sbjct: 65 GP-APTGMYPSVPPTGPPP--GPPAPFPPSGPSCPPPGGPYPAPTVPGPGPTGPYPTPNM 121
Query: 357 -------PFGSPM--GHPGPMPPHGMRGPPPLMPPHG--YTGPPRP-PPYGYQRGPLPPP 404
P+G+P GP+ P G P P G Y P P P G P PP
Sbjct: 122 PFPELPRPYGAPTDPAAAGPLGPWGSMSSGPWAPGMGGQYPTPNMPYPSPGPYPAPPPPQ 181
Query: 405 RPTPRPPVP----PRGPLRGPLP 423
P PPVP P G P P
Sbjct: 182 APGAAPPVPWGTVPPGAWGPPAP 204
Score = 60.5 bits (145), Expect = 3e-09
Identities = 53/147 (36%), Positives = 63/147 (42%), Gaps = 29/147 (19%)
Query: 200 PLSQADRPHQLFADAPPPPSAPNPVV--SSLGSGLPPPGMPPPGSFPPP-VPPPGALPPG 256
P + RP+ AP P+A P+ S+ SG PGM G +P P +P P PG
Sbjct: 122 PFPELPRPY----GAPTDPAAAGPLGPWGSMSSGPWAPGMG--GQYPTPNMPYPS---PG 172
Query: 257 IPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGP 316
PA PPPP PGAA P PGA P P+P P G P PG+
Sbjct: 173 PYPA-PPPPQAPGAAPPVPWGTVPPGAWGP----PAPYPAPTGSYPTPGLYPTP------ 221
Query: 317 HGLGHPHAGPPGSGGQPPPRPPPGMPH 343
+P P G G P P PG PH
Sbjct: 222 ---SNPFQVPSGPSGAP---PMPGGPH 242
Score = 47.8 bits (112), Expect = 2e-05
Identities = 30/77 (38%), Positives = 36/77 (46%), Gaps = 12/77 (15%)
Query: 214 APPPPSAPNPVVSSLGSGLPPP-GMPPPGSFPPPVP---PPGALP-PGIPPAMPPPPMPP 268
APPPP AP G+ P P G PPG++ PP P P G+ P PG+ P P P
Sbjct: 176 APPPPQAP-------GAAPPVPWGTVPPGAWGPPAPYPAPTGSYPTPGLYPTPSNPFQVP 228
Query: 269 GAAGHGPPSAGTPGAGH 285
PP G P + H
Sbjct: 229 SGPSGAPPMPGGPHSYH 245
>gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]
Length = 392
Score = 96.7 bits (239), Expect = 4e-20
Identities = 65/193 (33%), Positives = 98/193 (50%), Gaps = 19/193 (9%)
Query: 6 ISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVN----THMPKDRVTGQHQG------ 55
+ + Q T+YVG L V+E L+ +LF Q GP + T P R G
Sbjct: 2 MEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQH 61
Query: 56 -----YGFVEFLSEEDADYAIKIMNMIKLYGKPIRVNKA---SAHNKNLDVGANIFIGNL 107
Y FVEF DA A+ MN K+ GK ++VN A S+ K+ ++F+G+L
Sbjct: 62 TSNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDL 121
Query: 108 DPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYL 167
PEI + + F+ FG I ++++D TG SKGY F++F + ++ AI M GQ+L
Sbjct: 122 SPEITTEDIKSAFAPFGKISDA-RVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWL 180
Query: 168 CNRPITVSYAFKK 180
R I ++A +K
Sbjct: 181 GGRQIRTNWATRK 193
Score = 67.4 bits (163), Expect = 2e-11
Identities = 50/187 (26%), Positives = 89/187 (47%), Gaps = 31/187 (16%)
Query: 2 AAGPISERNQDAT---VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGF 58
A P S++ + V+VG L +++ + F G + + + KD TG+ +GYGF
Sbjct: 100 ATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGF 159
Query: 59 VEFLSEEDADYAIKIMNMIKLYGKPIRVNKASAH---------------------NKNLD 97
V F ++ DA+ AI M L G+ IR N A+ N++
Sbjct: 160 VSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSP 219
Query: 98 VGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDA 157
++ G + + ++L+ TFS FG I++ I P+ KGY+F+ F++ +++
Sbjct: 220 KNCTVYCGGIASGLTDQLMRQTFSPFGQIME---IRVFPE----KGYSFVRFSTHESAAH 272
Query: 158 AIEAMNG 164
AI ++NG
Sbjct: 273 AIVSVNG 279
Score = 40.0 bits (92), Expect = 0.004
Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 19/105 (18%)
Query: 102 IFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDT---GNSKG-----------YAFI 147
+++GNL ++ E L+ FS G I PD+ +S G Y F+
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCFV 70
Query: 148 NFASFDASDAAIEAMNGQYLCNRPITVSYAF-----KKDSKGERH 187
F + AA+ AMNG+ + + + V++A KKD+ H
Sbjct: 71 EFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFH 115
Score = 28.9 bits (63), Expect = 9.2
Identities = 20/59 (33%), Positives = 24/59 (40%), Gaps = 4/59 (6%)
Query: 329 SGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTG 387
+G Q PP G P G P + MG G PP G PPP++PP G
Sbjct: 329 NGWQVPPYGVYGQPWN---QQGFGVDQSPSAAWMGGFGAQPPQGQA-PPPVIPPPNQAG 383
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 96.7 bits (239), Expect = 4e-20
Identities = 111/353 (31%), Positives = 134/353 (37%), Gaps = 70/353 (19%)
Query: 102 IFIGNLDPEIDEKLLYDTFSAFGV--ILQTPKIMRDPDTGNSKGYAFINFASFDASDAAI 159
++IGNL ++ L + + GV IL+ K + G SKG+A + S +S +
Sbjct: 83 LYIGNLTWWTTDEDLTEAVHSLGVNDILEI-KFFENRANGQSKGFALVGVGSEASSKKLM 141
Query: 160 EAMNGQYL---------CNRPITVSYAF---KKDSKGER--HGSAAERLLAAQNPLSQAD 205
+ + + L CN+ + K G+ G A +++ Q
Sbjct: 142 DLLPKRELHGQNPVVTPCNKQFLSQFEMQSRKTTQSGQMSGEGKAGPPGGSSRAAFPQGG 201
Query: 206 RPHQLFADAPPPPSA-PNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPP 264
R F A P P P G G PPP P P PP PP G PPG P PP
Sbjct: 202 RGRGRFPGAVPGGDRFPGPA----GPGGPPP--PFPAGQTPPRPPLG--PPG--PPGPPG 251
Query: 265 PMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHA 324
P PPG PP P AG P G P P G P G P
Sbjct: 252 PPPPGQVL--PP----PLAGPPNRGDRPPPPVLFPGQP----------------FGQPPL 289
Query: 325 GPPGSGGQPPPRPPPGM-PHPGPPPMGMPPRGPPFGSPMGHPGPM-------PPHGMRGP 376
GP G PP P PG P PGPPP P PP P PGP+ PP + GP
Sbjct: 290 GPLPPG---PPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGP 346
Query: 377 PPLMPPHGYTGPPR--PPPYGY------QRGPLPPPRPTPRPPVPPRGPLRGP 421
PP PP P PPP RGP PP P RPP RG P
Sbjct: 347 PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGP-PPTDPYGRPPPYDRGDYGPP 398
Score = 48.9 bits (115), Expect = 9e-06
Identities = 49/142 (34%), Positives = 49/142 (34%), Gaps = 50/142 (35%)
Query: 320 GHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPL 379
G AGPPG G P G G P G P G F P G PG GPPP
Sbjct: 182 GEGKAGPPG--GSSRAAFPQGGRGRGRFP-GAVPGGDRFPGPAG-PG--------GPPPP 229
Query: 380 MP-----------PHGYTGPPRPPPYGY----------QRGPLPPP-------------- 404
P P G GPP PPP G RG PPP
Sbjct: 230 FPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPL 289
Query: 405 ---RPTPRPPVPPRGPLRGPLP 423
P P PPVP GP GP P
Sbjct: 290 GPLPPGPPPPVPGYGPPPGPPP 311
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 96.7 bits (239), Expect = 4e-20
Identities = 77/236 (32%), Positives = 87/236 (36%), Gaps = 9/236 (3%)
Query: 194 LLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGAL 253
L A +PL+ P + A PPP AP + S GLP P + P + PP PP AL
Sbjct: 569 LQAPPSPLTTPP-PETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLAL 627
Query: 254 PPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPH--PGMSQMQL 311
PP P PP P P A A H P P PP P P +
Sbjct: 628 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 687
Query: 312 AHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPP-RGPPFGSPMGHPGPMPP 370
+ P A PP PP PP P PPP PP PP P P P
Sbjct: 688 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPM 747
Query: 371 HGMRGPPPLMPPHGYTGP---PRPPPYGYQRGPL--PPPRPTPRPPVPPRGPLRGP 421
PPP +PP P P PP PL PPP+ P PP L P
Sbjct: 748 SPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSP 803
Score = 81.6 bits (200), Expect = 1e-15
Identities = 73/238 (30%), Positives = 87/238 (36%), Gaps = 32/238 (13%)
Query: 208 HQLFADAPPPPSAPNPVVSSLGSGLPPPGMPP--PGSFPPP-VPPPGALPPGIPPAMPP- 263
H L A PPPS P + + PP PP P + PP PP A PP P PP
Sbjct: 659 HLLQAPFSPPPSPP------VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA 712
Query: 264 -PPMPPGAAGHGPPSAGTPGAGHPGHGHSHP---HPFPPGGMPHPGMSQMQLAHHGPHGL 319
PPM P A PP A P A P P P P P P + + A
Sbjct: 713 SPPMSPSAT--PPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP 770
Query: 320 GHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPL 379
P + P +PPP+ PP + P + PP P +P +P + PPP
Sbjct: 771 SPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 830
Query: 380 MPP----HGYTGPPRPPPYGYQRGPLPPPRPTP------------RPPVPPRGPLRGP 421
PP PP PP + P PP P P P PP P R P
Sbjct: 831 APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 888
Score = 78.6 bits (192), Expect = 1e-14
Identities = 72/229 (31%), Positives = 81/229 (35%), Gaps = 29/229 (12%)
Query: 216 PPPSAPNPVVSSLGSGLPPP------GMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPG 269
PP S P + +L S PPP + P PP P P L P PPP P
Sbjct: 526 PPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPS 585
Query: 270 AAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGS 329
+ PP A A P G P P P P P + LA P A PP S
Sbjct: 586 SIATPPPQAPPALASPPLQGLPSP-PLSPLATPPP-QAPPXLALPPLQAPPSPPASPPLS 643
Query: 330 G-GQPPPRPP----------PGMPHPGPPPMG--MPPRGPPFGSPMGHPGPMPPHGMRGP 376
P P+ P P P P PP PP PP SP P P + P
Sbjct: 644 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV-SPSATPPSQAPPSLAAP 702
Query: 377 PPLMPPHGYTGPPRPPPYGYQRGP---LPPPRPTPRPPVPPRGPLRGPL 422
P +PP PP PP P PPP P VPP P P+
Sbjct: 703 PLQVPP----SPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPM 747
Score = 65.5 bits (158), Expect = 9e-11
Identities = 73/245 (29%), Positives = 88/245 (35%), Gaps = 40/245 (16%)
Query: 214 APPPPSAPNPVVSSLGSGLPP-----PGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPP 268
A PPP AP P+ + +PP P M P + PP VPP A PP P PP +P
Sbjct: 720 ATPPPQAPPPLAAP-PLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPM 778
Query: 269 GAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPG 328
PP A A P P PG P + + ++ P P A P
Sbjct: 779 SPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS---PLATPPPQAPPVL 835
Query: 329 SGG--QPPPRPP--PGMPHPGPPPMGMPP---RGPPFGSPMGHPGPMPPHGMRGPPPLMP 381
+ Q PP PP P + P PP P GP + PGP PP L
Sbjct: 836 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA-PGPPPPPSRSPSSTLSG 894
Query: 382 PH--GYTGPPRPPP---YGYQRGP------LPPPRPT------------PRPPVPPRGPL 418
P G++ P GY GP PPP P PP+ RG
Sbjct: 895 PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAP 954
Query: 419 RGPLP 423
PLP
Sbjct: 955 GAPLP 959
Score = 63.9 bits (154), Expect = 3e-10
Identities = 82/310 (26%), Positives = 97/310 (31%), Gaps = 101/310 (32%)
Query: 214 APPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGAL----PPGIP-----PAMPPP 264
APP PSAP + + PP PP PP+ P +L P +P P++ P
Sbjct: 344 APPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAP 403
Query: 265 PMPPGAAG-HGPPSAGTPG--AGH----------------PGHGHSHPHPFPPGGMP--- 302
P P + S G+P A H P S P PP P
Sbjct: 404 PSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSL 463
Query: 303 -----------------------HPGMSQMQLAHHGPHG---------------LGHPHA 324
HP + LA H P L P
Sbjct: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523
Query: 325 GPPGSGGQPPP-------RPPP--------GMPHPGPPPMGMPP--RGPPFGSPMGHPGP 367
P + PP PPP PH PP P + PP SP+ P P
Sbjct: 524 QTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPP--SPLTTPPP 581
Query: 368 MPPHGMRGPPPLMPP-------HGYTGPP-----RPPPYGYQRGPLPPPRPTPRPPV-PP 414
P + PPP PP G PP PPP LPP + P PP PP
Sbjct: 582 ETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPP 641
Query: 415 RGPLRGPLPQ 424
PL P PQ
Sbjct: 642 LSPLATPSPQ 651
Score = 62.4 bits (150), Expect = 8e-10
Identities = 66/225 (29%), Positives = 82/225 (36%), Gaps = 49/225 (21%)
Query: 194 LLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPP---VPPP 250
L A +PLS H L A + +P +SSL + PP + S PP PP
Sbjct: 473 LSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSL---IMPP-LETQSSLAPPSLQTPPA 528
Query: 251 GALPPGIP--PAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQ 308
P + P++ PPP+ +A P TP P P P P P
Sbjct: 529 SLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPC---------PAPCPLQAPPSP---- 575
Query: 309 MQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPM 368
L P P S PPP+ PP + PP G+P PP SP+ P P
Sbjct: 576 ----------LTTPPPETPSSIATPPPQAPPALA--SPPLQGLP--SPPL-SPLATPPPQ 620
Query: 369 PPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVP 413
P + PP PP PP PP P TP P P
Sbjct: 621 APPXLALPPLQAPP----SPPASPPLS--------PLATPSPQAP 653
Score = 58.9 bits (141), Expect = 8e-09
Identities = 79/276 (28%), Positives = 89/276 (32%), Gaps = 78/276 (28%)
Query: 214 APP---PPSAP-NPVVSSLGSGLPPPGMPPPGSFPP---PVPPPGALPPGIPPAMPPPPM 266
APP PPS P +P +S S PPP +PP + PP P PP +LP P A PPP
Sbjct: 732 APPLQVPPSPPASPPMSP--SATPPPRVPPLLAAPPLQVPPSPPASLPMS-PLAKPPPQA 788
Query: 267 PPGAAGHGPPSAGTPGAGHPGHGHSHPH---PFPPGGMPHPGMSQMQLAHHGPHGLGHPH 323
PP A + +P A PG P P P P P + A L P
Sbjct: 789 PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL----LQVPP 844
Query: 324 AGPPGSGGQPPPRPPPGMPH-------------PGPPPMGMPPRGP-------------- 356
+ P Q P RPP P PGPPP P R P
Sbjct: 845 SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP--PSRSPSSTLSGPDLAGHSS 902
Query: 357 ---------------PFGSPMGHPGP-------MPPHGMRGPPPLMPPHGYTGPPRPPPY 394
P G P P P RGP P + G G P P P
Sbjct: 903 SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP 962
Query: 395 GYQRGPLP----------PPRPTPRPPVPPRGPLRG 420
G P TP P GP G
Sbjct: 963 ATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 998
Score = 53.9 bits (128), Expect = 3e-07
Identities = 81/314 (25%), Positives = 93/314 (29%), Gaps = 101/314 (32%)
Query: 203 QADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPP--------PGALP 254
QA RP Q+ PP P + L S P P G+ PVPP P LP
Sbjct: 278 QALRPPQV----TPPRKDAAPALGPLSSS-PLATPSPSGTKARPVPPPDNAATPLPATLP 332
Query: 255 PGIPPAMPPPPMPPGAA----------------GHGPPSAGTPGAGHPGHGHSHPHPFPP 298
P P A P P PP + PPS TP P PP
Sbjct: 333 PSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTP----PMQAPPSLQTIPP 388
Query: 299 GGMPHP------------------------GMSQMQLAHH----GPHGLGHPHAGPPGSG 330
+PH G +Q H P P
Sbjct: 389 IQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPA 448
Query: 331 GQPPPRPPPGMP--HPGPPPM--GMPPRGPPFGSPMG-HP----GPMPPHGMRGP----- 376
PP PP P P PP+ + P P SP+ HP + H + P
Sbjct: 449 STPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLI 508
Query: 377 -PPL------------MPPHGYTGPP-------RPPPYGYQRGPL------PPPRPTPRP 410
PPL PP T PP PPP PL PP P P P
Sbjct: 509 MPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP 568
Query: 411 PVPPRGPLRGPLPQ 424
P PL P P+
Sbjct: 569 LQAPPSPLTTPPPE 582
Score = 50.1 bits (118), Expect = 4e-06
Identities = 65/225 (28%), Positives = 75/225 (33%), Gaps = 44/225 (19%)
Query: 198 QNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLP--PPGMPPPGSFPPPVPPPGALPP 255
Q P + A P Q PP S P S + LP P PPP + PP + P P
Sbjct: 787 QAPPALATPPLQALPS--PPASFPGQAPFSPSASLPMSPLATPPPQA-PPVLAAPLLQVP 843
Query: 256 GIPPAMP-------PPPMPPGAAGHGP--PSAGTPGAGHPGHGHSHPHPFPPGGMPHPGM 306
PPA P PP P + GP A PG P PP P +
Sbjct: 844 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP-----------PPPPSRSPSSTL 892
Query: 307 SQMQLAHHGPHGLGHPH------AGPP-GSGGQPPPRPPPGMPHP-----GP-PPM---- 349
S LA H P +GP G+ PPP HP GP PP+
Sbjct: 893 SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRG 952
Query: 350 --GMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPP 392
G P PP P G + GP P G P P
Sbjct: 953 APGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 997
Score = 41.6 bits (96), Expect = 0.001
Identities = 60/242 (24%), Positives = 73/242 (30%), Gaps = 42/242 (17%)
Query: 220 APNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGI----------------PPAMPP 263
A P S G PP PG P G PG A
Sbjct: 91 ASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEA 150
Query: 264 PPMPPGAAGHGPPSAG-TPGAGHPGHGHSHPHPFPPGGMPHPGMS----------QMQLA 312
P +AG ++G TPG P G+P P S + ++
Sbjct: 151 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS 210
Query: 313 HHGPHGLGHPHAGP---PGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPF--GSPMG--HP 365
H P P +GG RP P+ P R P G+P HP
Sbjct: 211 SASEHSTTEPSPAARRRPSAGGGLQ-RPASRSLSSSATPLSSPARSGPSARGTPRAPAHP 269
Query: 366 GPMPPHGMRG--PPPLMPPHGYTGPPRPPPYGYQRGPLPPPRP--TPRPPVPPRGPLRGP 421
P G++ PP + PP P P PL P P T PVPP P
Sbjct: 270 SQPKPKGLQALRPPQVTPPRKDAAPALGP---LSSSPLATPSPSGTKARPVPPPDNAATP 326
Query: 422 LP 423
LP
Sbjct: 327 LP 328
Score = 40.8 bits (94), Expect = 0.002
Identities = 50/195 (25%), Positives = 59/195 (30%), Gaps = 28/195 (14%)
Query: 245 PPVPPPGAL---PPGIPPAMPPPPMPP---------GAAGHGPPSAGTPGAGHPGHGHSH 292
P PG L PPG P PPPP+ P GA G P + G G G +
Sbjct: 17 PAARAPGLLTPRPPGSP--RPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG----GATI 70
Query: 293 PHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMP 352
P P G + + P G PP P P PG P +
Sbjct: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 130
Query: 353 PRGPPFGS----PMGHPGPMPPHGMRGPPPLMPPHGYT-GPPRPPPYGYQRGP-----LP 402
+G + G P G T G P P R LP
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP 190
Query: 403 PPRPTPRPPVPPRGP 417
P P+ RP P GP
Sbjct: 191 RPAPSARPRPPTEGP 205
Score = 28.9 bits (63), Expect = 9.2
Identities = 28/101 (27%), Positives = 34/101 (33%), Gaps = 13/101 (12%)
Query: 328 GSGGQPPPRPPPGMPHPGPP--PMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGY 385
G+ + P PG+ P PP P PP P +G G + G PL G
Sbjct: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAV------GRKPLAERAGG 64
Query: 386 TGPPRPPPYGYQRGP-----LPPPRPTPRPPVPPRGPLRGP 421
G P + GP P RPP RG P
Sbjct: 65 IGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPP 105
>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
[Homo sapiens]
Length = 1125
Score = 96.7 bits (239), Expect = 4e-20
Identities = 91/247 (36%), Positives = 106/247 (42%), Gaps = 53/247 (21%)
Query: 207 PHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPP-------PGALPPGIPP 259
PHQ PP A P + G+PPPG P PPP PP P LPPG P
Sbjct: 684 PHQ---PGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLP 740
Query: 260 AMPPPPMPPGAA---GHGPPSA------GTPGAGHPG-----HGHSHPHPFPPGGMPHPG 305
PPPP+ P + H PP + G G G +G + P P P +P P
Sbjct: 741 PGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVP-PAAPTNLPTPP 799
Query: 306 MSQ------MQLAHHGPH-GLGHPHAGPPGSG-GQPPPRPPPGMPHPGPPPMGMPPRGPP 357
++Q Q GP GL P G G+ G P + PPGMP PP
Sbjct: 800 VTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMP---------PPHLQR 850
Query: 358 FGSPMGHPGPMPPHGM-RGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPP-- 414
F P+ P PMPPH M RGPPP G G PPP+G +GP PP P RP P
Sbjct: 851 F--PLMPPRPMPPHMMHRGPPP-----GPGGFAMPPPHG-MKGPFPPHGPFVRPGGMPGL 902
Query: 415 RGPLRGP 421
GP GP
Sbjct: 903 GGPGPGP 909
Score = 84.0 bits (206), Expect = 2e-16
Identities = 92/287 (32%), Positives = 111/287 (38%), Gaps = 94/287 (32%)
Query: 222 NPVVSSLGSGLPPPGMPPPGSFPPP-------------------------VPPPGALPPG 256
+P+ L +PP +P P + PPP +PPPG PG
Sbjct: 656 SPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPG-FGPG 714
Query: 257 IPPAMPPPP----------MPPGAAGHGPPSAGTPGAGHPG------------------- 287
+PP PPPP +PPG GPP TP P
Sbjct: 715 VPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNA 774
Query: 288 --------HGHSHPHPFPPGGMPHPGMSQ------MQLAHHGP-HGLGHPHAGPPGS-GG 331
+G + P P P +P P ++Q Q GP GL P G G+ G
Sbjct: 775 ESGDSVKMYGSAVP-PAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPG 833
Query: 332 QPPPRPPPGMPHPG------PPPMGMPP----RGPPFGSPMGHPGPMPPHGMRGPPPLMP 381
P + PPGMP P PP MPP RGPP G P G P PPHGM+GP P
Sbjct: 834 LIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPG-PGGFAMP-PPHGMKGP---FP 888
Query: 382 PHG-YTGPPRPPPYGYQRGPLP-PPRPTPRP--PVPPRGPLRGPLPQ 424
PHG + P P G GP P P P R PP+ P + P PQ
Sbjct: 889 PHGPFVRPGGMPGLG---GPGPGPGGPEDRDGRQQPPQQPQQQPQPQ 932
Score = 53.5 bits (127), Expect = 4e-07
Identities = 44/129 (34%), Positives = 55/129 (42%), Gaps = 15/129 (11%)
Query: 304 PGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGP---PPMGMPPR--GPPF 358
P + ++A +G G H P +P P P P +P P P PP +PP GPP
Sbjct: 634 PKKPENEVAQNG--GAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPV 691
Query: 359 GSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPP----YGYQRGPLPPPRPTPRPPVPP 414
+ P PP G+ PPP P PP PPP G+ LPP P PP P
Sbjct: 692 VGALQPPAFTPPLGI--PPPGFGPG--VPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPI 747
Query: 415 RGPLRGPLP 423
P+ P P
Sbjct: 748 TPPVSIPPP 756
Score = 41.6 bits (96), Expect = 0.001
Identities = 42/115 (36%), Positives = 48/115 (41%), Gaps = 15/115 (13%)
Query: 249 PPGALPPGIPPAMPPPPMPPGAAGHGPPSA--GTPGAG--HPGH-GHSHPHPFPPGGMPH 303
P A+PP P A P P AA PP A G PG G P + H + F P M
Sbjct: 290 PAAAVPPA-PTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMM-- 346
Query: 304 PGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPF 358
G+ Q + H P P+ PG G P P P P M P PP PP PF
Sbjct: 347 -GIQQDPMHHQVPL---PPNGQMPGFGLLPTP-PFPPMAQPVIPP--TPPVQQPF 394
Score = 40.4 bits (93), Expect = 0.003
Identities = 32/116 (27%), Positives = 41/116 (35%), Gaps = 41/116 (35%)
Query: 322 PHAGPPGSGGQPPPRPPPGMPHPG----------------PPPMGMPPRGPPFGSPMGHP 365
P A P + PPP+ P G P G P MG+ PM H
Sbjct: 303 PAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQ------DPMHHQ 356
Query: 366 GPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRGP 421
P+PP+G MP G P PP P +P +PP P++ P
Sbjct: 357 VPLPPNGQ------MPGFGLL-------------PTPPFPPMAQPVIPPTPPVQQP 393
Score = 32.0 bits (71), Expect = 1.1
Identities = 33/125 (26%), Positives = 41/125 (32%), Gaps = 39/125 (31%)
Query: 212 ADAPPPPSAPNPVVSSLGSGLPPP-----GMPPPGSFPP--------------------- 245
A PP P+A P ++ + PPP G P G P
Sbjct: 292 AAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQD 351
Query: 246 ------PVPPPGALPP-GIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPP 298
P+PP G +P G+ +P PP PP A PP TP P P
Sbjct: 352 PMHHQVPLPPNGQMPGFGL---LPTPPFPPMAQPVIPP---TPPVQQPFQASFQAQNEPL 405
Query: 299 GGMPH 303
PH
Sbjct: 406 TQKPH 410
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 96.3 bits (238), Expect = 5e-20
Identities = 78/253 (30%), Positives = 94/253 (37%), Gaps = 42/253 (16%)
Query: 189 SAAERLLAAQNP---LSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMP----PPG 241
S E AA+ P + + + H A PPP P+ ++LG PP + P
Sbjct: 340 SPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKV 399
Query: 242 SFPPPV-PPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGH-----------PGHG 289
PPP P P PP +P PPPP G S+ G G+ P +G
Sbjct: 400 QIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYG 459
Query: 290 HSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPG--PP 347
P PP +P+ HPH PP P P PP P P PP
Sbjct: 460 ALPPAYGPPAHLPY-----------------HPHVYPPNPPPPPVPPPPASFPPPAIPPP 502
Query: 348 PMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPR--PPPYGYQRGPLPPPR 405
G PP P + P P P PP PP G PP PPP G P P
Sbjct: 503 TPGYPPPPPTYNPNFPPPPPRLPPTHAVPPH--PPPGLGLPPASYPPPAVPPGGQPPVPP 560
Query: 406 PTPRPPVPPRGPL 418
P P P +PP G L
Sbjct: 561 PIPPPGMPPVGGL 573
Score = 37.7 bits (86), Expect = 0.020
Identities = 29/121 (23%), Positives = 38/121 (31%), Gaps = 6/121 (4%)
Query: 308 QMQLAHHGPHGLGHPHA------GPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSP 361
+ Q+ HH PH L P + P QP P P P + P
Sbjct: 262 KQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPK 321
Query: 362 MGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRGP 421
P P P ++ + P PPP + PP P PP + PL
Sbjct: 322 KPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAA 381
Query: 422 L 422
L
Sbjct: 382 L 382
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.142 0.468
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,278,188
Number of Sequences: 37866
Number of extensions: 3473936
Number of successful extensions: 102900
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1586
Number of HSP's successfully gapped in prelim test: 2148
Number of HSP's that attempted gapping in prelim test: 16084
Number of HSP's gapped (non-prelim): 28886
length of query: 424
length of database: 18,247,518
effective HSP length: 105
effective length of query: 319
effective length of database: 14,271,588
effective search space: 4552636572
effective search space used: 4552636572
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.