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Search of human proteins with 5031761
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5031761 homeobox A1 isoform a [Homo sapiens]
(335 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5031761 homeobox A1 isoform a [Homo sapiens] 704 0.0
gi|84697022 homeobox A1 isoform b [Homo sapiens] 258 5e-69
gi|24497526 homeobox B1 [Homo sapiens] 208 5e-54
gi|13375632 homeobox D1 [Homo sapiens] 158 7e-39
gi|4504465 homeobox B2 [Homo sapiens] 99 4e-21
gi|23397672 homeobox D4 [Homo sapiens] 99 7e-21
gi|24497538 homeobox C4 [Homo sapiens] 99 7e-21
gi|24497540 homeobox C4 [Homo sapiens] 99 7e-21
gi|19923391 homeobox D3 [Homo sapiens] 95 1e-19
gi|24497517 homeobox A5 [Homo sapiens] 92 5e-19
gi|148613882 homeobox A4 [Homo sapiens] 92 8e-19
gi|24497513 homeobox A3 isoform a [Homo sapiens] 91 1e-18
gi|13562112 homeobox A3 isoform a [Homo sapiens] 91 1e-18
gi|13273315 homeobox B4 [Homo sapiens] 91 1e-18
gi|84105335 mesenchyme homeobox 2 [Homo sapiens] 91 2e-18
gi|10140847 homeobox A2 [Homo sapiens] 90 3e-18
gi|13489077 homeobox A6 [Homo sapiens] 88 1e-17
gi|24497556 homeobox A7 [Homo sapiens] 87 2e-17
gi|11321638 homeobox C5 [Homo sapiens] 87 2e-17
gi|169636435 caudal type homeobox 2 [Homo sapiens] 87 2e-17
gi|89257348 homeo box HB9 [Homo sapiens] 87 2e-17
gi|12056969 homeobox C8 [Homo sapiens] 87 2e-17
gi|4504469 homeobox B5 [Homo sapiens] 87 3e-17
gi|23503237 homeobox B6 [Homo sapiens] 86 6e-17
gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens] 85 1e-16
gi|23097236 homeobox A9 [Homo sapiens] 85 1e-16
gi|15029506 homeobox D8 [Homo sapiens] 84 1e-16
gi|24497515 homeobox A3 isoform b [Homo sapiens] 84 1e-16
gi|85068580 homeobox B7 [Homo sapiens] 84 2e-16
gi|84570137 homeobox B3 [Homo sapiens] 84 2e-16
>gi|5031761 homeobox A1 isoform a [Homo sapiens]
Length = 335
Score = 704 bits (1818), Expect = 0.0
Identities = 335/335 (100%), Positives = 335/335 (100%)
Query: 1 MDNARMNSFLEYPILSSGDSGTCSARAYPSDHRITTFQSCAVSANSCGGDDRFLVGRGVQ 60
MDNARMNSFLEYPILSSGDSGTCSARAYPSDHRITTFQSCAVSANSCGGDDRFLVGRGVQ
Sbjct: 1 MDNARMNSFLEYPILSSGDSGTCSARAYPSDHRITTFQSCAVSANSCGGDDRFLVGRGVQ 60
Query: 61 IGSPHHHHHHHHHHPQPATYQTSGNLGVSYSHSSCGPSYGSQNFSAPYSPYALNQEADVS 120
IGSPHHHHHHHHHHPQPATYQTSGNLGVSYSHSSCGPSYGSQNFSAPYSPYALNQEADVS
Sbjct: 61 IGSPHHHHHHHHHHPQPATYQTSGNLGVSYSHSSCGPSYGSQNFSAPYSPYALNQEADVS 120
Query: 121 GGYPQCAPAVYSGNLSSPMVQHHHHHQGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSL 180
GGYPQCAPAVYSGNLSSPMVQHHHHHQGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSL
Sbjct: 121 GGYPQCAPAVYSGNLSSPMVQHHHHHQGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSL 180
Query: 181 SPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQ 240
SPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQ
Sbjct: 181 SPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQ 240
Query: 241 LTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATP 300
LTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATP
Sbjct: 241 LTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATP 300
Query: 301 PGNDEKAEESSEKSSSSPCVPSPGSSTSDTLTTSH 335
PGNDEKAEESSEKSSSSPCVPSPGSSTSDTLTTSH
Sbjct: 301 PGNDEKAEESSEKSSSSPCVPSPGSSTSDTLTTSH 335
>gi|84697022 homeobox A1 isoform b [Homo sapiens]
Length = 137
Score = 258 bits (659), Expect = 5e-69
Identities = 118/118 (100%), Positives = 118/118 (100%)
Query: 1 MDNARMNSFLEYPILSSGDSGTCSARAYPSDHRITTFQSCAVSANSCGGDDRFLVGRGVQ 60
MDNARMNSFLEYPILSSGDSGTCSARAYPSDHRITTFQSCAVSANSCGGDDRFLVGRGVQ
Sbjct: 1 MDNARMNSFLEYPILSSGDSGTCSARAYPSDHRITTFQSCAVSANSCGGDDRFLVGRGVQ 60
Query: 61 IGSPHHHHHHHHHHPQPATYQTSGNLGVSYSHSSCGPSYGSQNFSAPYSPYALNQEAD 118
IGSPHHHHHHHHHHPQPATYQTSGNLGVSYSHSSCGPSYGSQNFSAPYSPYALNQEAD
Sbjct: 61 IGSPHHHHHHHHHHPQPATYQTSGNLGVSYSHSSCGPSYGSQNFSAPYSPYALNQEAD 118
>gi|24497526 homeobox B1 [Homo sapiens]
Length = 301
Score = 208 bits (530), Expect = 5e-54
Identities = 144/337 (42%), Positives = 184/337 (54%), Gaps = 45/337 (13%)
Query: 1 MDNARMNSFLEYPILSSGDSGTCSARAYPSDHRITTFQ-SCAVSANSCGGDDRFLVGRGV 59
MD RMNSFLEYP+ + G S AY + T+F S A + +S + R+ G
Sbjct: 1 MDYNRMNSFLEYPLCNRGPS------AYSAHSAPTSFPPSSAQAVDSYASEGRY----GG 50
Query: 60 QIGSPHHHHHHHHHHPQPAT-----YQTSGNLGVSYSHSSCGPSYGSQNFSAPYSPYALN 114
+ SP + + QP + + +S G Y+ ++C PSYG + Y L
Sbjct: 51 GLSSPAFQQNSGYPAQQPPSTLGVPFPSSAPSG--YAPAACSPSYGPSQY------YPLG 102
Query: 115 QEADVSGGYPQCAPAVYSGNLSSPMVQHHHHHQGYAGGAVGSPQYI--HHSYGQEHQSLA 172
Q G + + G LS GY G G Y H YG E +
Sbjct: 103 QSEGDGGYFHPSSYGAQLGGLSD----------GYGAGGAGPGPYPPQHPPYGNEQTASF 152
Query: 173 LATYNNSLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAV 232
Y + LS + C P+ + A+TFDWMKVKRNPPKT KV E G LG P+ +
Sbjct: 153 APAYADLLSE---DKETPC--PSEPNTPTARTFDWMKVKRNPPKTAKVSEPG-LGSPSGL 206
Query: 233 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK-EG 291
RTNFTT+QLTELEKEFHFNKYL+RARRVEIAA+L+LNETQVKIWFQNRRMKQKKRE+ EG
Sbjct: 207 RTNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQKKREREEG 266
Query: 292 LLPISPATPPGNDEKAEESSEKSSSSPCVPSPGSSTS 328
+P PA P E A ++S++S+ + SP S TS
Sbjct: 267 RVP--PAPPGCPKEAAGDASDQSTCTSPEASPSSVTS 301
>gi|13375632 homeobox D1 [Homo sapiens]
Length = 328
Score = 158 bits (399), Expect = 7e-39
Identities = 108/257 (42%), Positives = 132/257 (51%), Gaps = 41/257 (15%)
Query: 76 QPATYQTSGNLGVSYSHSSCGPSYGSQNFSAPYSPYALNQEADVSGGYPQCAP-AVYSGN 134
+P + G Y GP+Y P L + AD G + A AV+SG
Sbjct: 92 EPGAAPAAAAGGADYGFLGSGPAYDF--------PGVLGRAADDGGSHVHYATSAVFSGG 143
Query: 135 ---LSSPMVQHHHHHQGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHASHQEAC 191
L S V + + A H + S A TY S+SP
Sbjct: 144 GSFLLSGQVDYAAFGEPGPFPACLKASADGHPGAFQTASPAPGTYPKSVSP--------- 194
Query: 192 RSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFN 251
AS + TF+WMKVKRN K GK+ EYG +A+RTNF+TKQLTELEKEFHFN
Sbjct: 195 ---ASGLPAAFSTFEWMKVKRNASKKGKLAEYGAASPSSAIRTNFSTKQLTELEKEFHFN 251
Query: 252 KYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGL-----------LPISPATP 300
KYLTRARR+EIA L LN+TQVKIWFQNRRMKQKKRE+EGL LP+S TP
Sbjct: 252 KYLTRARRIEIANCLHLNDTQVKIWFQNRRMKQKKREREGLLATAIPVAPLQLPLSGTTP 311
Query: 301 ------PGNDEKAEESS 311
PG+ +++E S
Sbjct: 312 TKFIKNPGSPSQSQEPS 328
>gi|4504465 homeobox B2 [Homo sapiens]
Length = 356
Score = 99.4 bits (246), Expect = 4e-21
Identities = 63/153 (41%), Positives = 78/153 (50%), Gaps = 24/153 (15%)
Query: 194 PASETSSPAQTFDWMKVKRNP-----------------PKTGKVGEYGYLGQPNA----- 231
P + PA F WMK K++ P +G LG P A
Sbjct: 84 PPLPAAPPAPEFPWMKEKKSAKKPSQSATSPSPAASAVPASGVGSPADGLGLPEAGGGGA 143
Query: 232 --VRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 289
+RT +T QL ELEKEFHFNKYL R RRVEIAA L L E QVK+WFQNRRMK K++ +
Sbjct: 144 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ 203
Query: 290 EGLLPISPATPPGNDEKAEESSEKSSSSPCVPS 322
P PG E + +E+ ++SP PS
Sbjct: 204 HREPPDGEPACPGALEDICDPAEEPAASPGGPS 236
>gi|23397672 homeobox D4 [Homo sapiens]
Length = 255
Score = 98.6 bits (244), Expect = 7e-21
Identities = 63/144 (43%), Positives = 76/144 (52%), Gaps = 23/144 (15%)
Query: 185 ASHQEACRSPASETS--SPAQTFDWMKVKR----NPPKTGKVGEYGYLGQPNAVRTNFTT 238
A Q + P S T+ PA + WMK NP TG G+P RT +T
Sbjct: 112 AYSQSDPKQPPSGTALKQPAVVYPWMKKVHVNSVNPNYTG--------GEPKRSRTAYTR 163
Query: 239 KQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPA 298
+Q+ ELEKEFHFN+YLTR RR+EIA +L L+E Q+KIWFQNRRMK KK K
Sbjct: 164 QQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHK--------- 214
Query: 299 TPPGNDEKAEESSEKSSSSPCVPS 322
P + SS S SS PS
Sbjct: 215 LPNTKGRSSSSSSSSSCSSSVAPS 238
>gi|24497538 homeobox C4 [Homo sapiens]
Length = 264
Score = 98.6 bits (244), Expect = 7e-21
Identities = 71/209 (33%), Positives = 92/209 (44%), Gaps = 39/209 (18%)
Query: 124 PQCAPAVYSGNLSSPMVQHHHHH---------------------QGYAGGAVGSPQYIHH 162
P+ +P Y G QHHH QG P H
Sbjct: 30 PEHSPEYY-GRTRESGFQHHHQELYPPPPPRPSYPERQYSCTSLQGPGNSRGHGPAQAGH 88
Query: 163 SYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQT-----FDWMKVKR----N 213
+ ++ QSL + S + AC PA + S A + + WMK N
Sbjct: 89 HHPEKSQSLCEPAPLSGASASPSPAPPACSQPAPDHPSSAASKQPIVYPWMKKIHVSTVN 148
Query: 214 PPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQV 273
P G G+P RT +T +Q+ ELEKEFH+N+YLTR RR+EIA SL L+E Q+
Sbjct: 149 PNYNG--------GEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQI 200
Query: 274 KIWFQNRRMKQKKREKEGLLPISPATPPG 302
KIWFQNRRMK KK + + A P G
Sbjct: 201 KIWFQNRRMKWKKDHRLPNTKVRSAPPAG 229
>gi|24497540 homeobox C4 [Homo sapiens]
Length = 264
Score = 98.6 bits (244), Expect = 7e-21
Identities = 71/209 (33%), Positives = 92/209 (44%), Gaps = 39/209 (18%)
Query: 124 PQCAPAVYSGNLSSPMVQHHHHH---------------------QGYAGGAVGSPQYIHH 162
P+ +P Y G QHHH QG P H
Sbjct: 30 PEHSPEYY-GRTRESGFQHHHQELYPPPPPRPSYPERQYSCTSLQGPGNSRGHGPAQAGH 88
Query: 163 SYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQT-----FDWMKVKR----N 213
+ ++ QSL + S + AC PA + S A + + WMK N
Sbjct: 89 HHPEKSQSLCEPAPLSGASASPSPAPPACSQPAPDHPSSAASKQPIVYPWMKKIHVSTVN 148
Query: 214 PPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQV 273
P G G+P RT +T +Q+ ELEKEFH+N+YLTR RR+EIA SL L+E Q+
Sbjct: 149 PNYNG--------GEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQI 200
Query: 274 KIWFQNRRMKQKKREKEGLLPISPATPPG 302
KIWFQNRRMK KK + + A P G
Sbjct: 201 KIWFQNRRMKWKKDHRLPNTKVRSAPPAG 229
>gi|19923391 homeobox D3 [Homo sapiens]
Length = 432
Score = 94.7 bits (234), Expect = 1e-19
Identities = 86/276 (31%), Positives = 110/276 (39%), Gaps = 29/276 (10%)
Query: 76 QPATYQTSGNLGVSYSHSSCGPSYGSQNFSAPYSPYALNQEAD---------VSGGYPQC 126
Q A Y + L Y +S +YG PY P A D + P
Sbjct: 18 QKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLDTDYPGSACSIQSSAPLR 77
Query: 127 APAVYSGNLSSPMVQHHHHHQGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHAS 186
APA L+ ++ + GG P +S Q Q SP +
Sbjct: 78 APAHKGAELNGSCMRPGTGNSQGGGGGSQPPGL--NSEQQPPQPPPPPPTLPPSSPTNPG 135
Query: 187 HQEACRSP-------ASETSSPAQTFDWMKVKRNPPKT----GKVGEYGYLGQP-----N 230
+ P +S + Q F WMK R K GE P
Sbjct: 136 GGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATAGESCEDKSPPGPASK 195
Query: 231 AVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKE 290
VRT +T+ QL ELEKEFHFN+YL R RRVE+A L L E Q+KIWFQNRRMK KK +K
Sbjct: 196 RVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKA 255
Query: 291 GLLPISPA--TPPGNDEKAEESSEKSSSSPCVPSPG 324
+ SPA +P + + + S P PG
Sbjct: 256 KGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPG 291
>gi|24497517 homeobox A5 [Homo sapiens]
Length = 270
Score = 92.4 bits (228), Expect = 5e-19
Identities = 65/194 (33%), Positives = 90/194 (46%), Gaps = 12/194 (6%)
Query: 98 SYGSQNFSAPYSPYALNQEADVSGGYPQCAPAVYSGNLSSPMVQHHHHHQGYAGGAVGSP 157
SY + +AP P +Q A S PQ P S SP HH + + G+
Sbjct: 72 SYAASASAAPAEP-RYSQPA-TSTHSPQPDPLPCSAVAPSPGSDSHHGGKNSLSNSSGAS 129
Query: 158 QYIHHSYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKT 217
++ + + A+ +P + A P+ + Q + WM+
Sbjct: 130 ADAGSTHISSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQIYPWMRKLHI---- 185
Query: 218 GKVGEYGYLGQPNA--VRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKI 275
+ +G P RT +T Q ELEKEFHFN+YLTR RR+EIA +L L+E Q+KI
Sbjct: 186 ----SHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKI 241
Query: 276 WFQNRRMKQKKREK 289
WFQNRRMK KK K
Sbjct: 242 WFQNRRMKWKKDNK 255
>gi|148613882 homeobox A4 [Homo sapiens]
Length = 320
Score = 91.7 bits (226), Expect = 8e-19
Identities = 63/154 (40%), Positives = 80/154 (51%), Gaps = 23/154 (14%)
Query: 190 ACRSPASETSSPAQTFDWMKVKR----NPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELE 245
A +SP + WMK NP G G+P RT +T +Q+ ELE
Sbjct: 180 ADKSPLGLKGKEPVVYPWMKKIHVSAVNPSYNG--------GEPKRSRTAYTRQQVLELE 231
Query: 246 KEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGNDE 305
KEFHFN+YLTR RR+EIA +L L+E QVKIWFQNRRMK KK K P T +
Sbjct: 232 KEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHK------LPNTKMRSSN 285
Query: 306 KAEESS----EKSSSSPCV-PSPGSSTSDTLTTS 334
A S+ + + SP + P P STS + +S
Sbjct: 286 SASASAGPPGKAQTQSPHLHPHPHPSTSTPVPSS 319
>gi|24497513 homeobox A3 isoform a [Homo sapiens]
Length = 443
Score = 91.3 bits (225), Expect = 1e-18
Identities = 59/137 (43%), Positives = 78/137 (56%), Gaps = 16/137 (11%)
Query: 177 NNSLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPK-------TGK--VGEYGYLG 227
+N+ +P +A+ SP + Q F WMK R K +G+ G+ G
Sbjct: 132 SNNPTPANAAKSPLLNSP----TVAKQIFPWMKESRQNTKQKTSSSSSGESCAGDKSPPG 187
Query: 228 QPNA--VRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQK 285
Q ++ RT +T+ QL ELEKEFHFN+YL R RRVE+A L L E Q+KIWFQNRRMK K
Sbjct: 188 QASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYK 247
Query: 286 KREK-EGLLPISPATPP 301
K +K +G+L S P
Sbjct: 248 KDQKGKGMLTSSGGQSP 264
>gi|13562112 homeobox A3 isoform a [Homo sapiens]
Length = 443
Score = 91.3 bits (225), Expect = 1e-18
Identities = 59/137 (43%), Positives = 78/137 (56%), Gaps = 16/137 (11%)
Query: 177 NNSLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPK-------TGK--VGEYGYLG 227
+N+ +P +A+ SP + Q F WMK R K +G+ G+ G
Sbjct: 132 SNNPTPANAAKSPLLNSP----TVAKQIFPWMKESRQNTKQKTSSSSSGESCAGDKSPPG 187
Query: 228 QPNA--VRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQK 285
Q ++ RT +T+ QL ELEKEFHFN+YL R RRVE+A L L E Q+KIWFQNRRMK K
Sbjct: 188 QASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYK 247
Query: 286 KREK-EGLLPISPATPP 301
K +K +G+L S P
Sbjct: 248 KDQKGKGMLTSSGGQSP 264
>gi|13273315 homeobox B4 [Homo sapiens]
Length = 251
Score = 90.9 bits (224), Expect = 1e-18
Identities = 53/114 (46%), Positives = 66/114 (57%), Gaps = 21/114 (18%)
Query: 181 SPLHAS-HQEACRSPASETSSPAQTFDWMKVKR----NPPKTGKVGEYGYLGQPNAVRTN 235
+PLH S AC+ P + WM+ NP G G+P RT
Sbjct: 125 NPLHPSPSHSACKEPV--------VYPWMRKVHVSTVNPNYAG--------GEPKRSRTA 168
Query: 236 FTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 289
+T +Q+ ELEKEFH+N+YLTR RRVEIA +L L+E Q+KIWFQNRRMK KK K
Sbjct: 169 YTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRMKWKKDHK 222
>gi|84105335 mesenchyme homeobox 2 [Homo sapiens]
Length = 304
Score = 90.5 bits (223), Expect = 2e-18
Identities = 83/281 (29%), Positives = 115/281 (40%), Gaps = 76/281 (27%)
Query: 10 LEYPILSSGDSGTCSARAYPSDHRITTFQSCAVSANSCGGDDRFLVGRGVQIGSPHHHHH 69
+ YP LS+ S +C YP++ + Q G HHHHH
Sbjct: 36 MSYPELSTSSS-SCIIAGYPNEEGMFASQH--------------------HRGHHHHHHH 74
Query: 70 HHHHHPQPATYQTSGNLGVSYSHSSCGPSYGSQNFSAPYSP--YALNQEADVSGGYPQC- 126
HHHHH Q H + ++ S+P S ++L + D SGG P+
Sbjct: 75 HHHHHHQ------------QQQHQALQTNWHLPQMSSPPSAARHSLCLQPD-SGGPPELG 121
Query: 127 -APAVYSGNLSSPMVQHHHHHQGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHA 185
+P V N SS GA +P YG++ +LSP A
Sbjct: 122 SSPPVLCSNSSSL-------GSSTPTGAACAPG----DYGRQ-----------ALSPAEA 159
Query: 186 SHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELE 245
+ + + + S + K + N +P RT FT +Q+ ELE
Sbjct: 160 EKRSGGKRKSDSSDSQEGNY---KSEVN-------------SKPRKERTAFTKEQIRELE 203
Query: 246 KEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 286
EF + YLTR RR EIA +L L E QVK+WFQNRRMK K+
Sbjct: 204 AEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMKWKR 244
>gi|10140847 homeobox A2 [Homo sapiens]
Length = 376
Score = 89.7 bits (221), Expect = 3e-18
Identities = 63/176 (35%), Positives = 77/176 (43%), Gaps = 33/176 (18%)
Query: 173 LATYNNSLSPLHASHQEACRSPASETSSPAQT-------FDWMKVKRNPPKTGKVGEY-- 223
+ + N P H + SPA SP + WMK K+ KT +
Sbjct: 56 IPSLNPGSHPRHGAGGRPKPSPAGSRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAA 115
Query: 224 ----------------------GYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVE 261
G G +RT +T QL ELEKEFHFNKYL R RRVE
Sbjct: 116 AATAAATGPACLSHKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVE 175
Query: 262 IAASLQLNETQVKIWFQNRRMKQKKRE--KEGLLPISPATPPGNDEKAEESSEKSS 315
IAA L L E QVK+WFQNRRMK K++ KE + EK EE E+ +
Sbjct: 176 IAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKCKSLEDSEKVEEDEEEKT 231
>gi|13489077 homeobox A6 [Homo sapiens]
Length = 233
Score = 87.8 bits (216), Expect = 1e-17
Identities = 59/159 (37%), Positives = 81/159 (50%), Gaps = 21/159 (13%)
Query: 150 AGGAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQTFDWMK 209
+G G Y+H S Q+++ ++S A H E ++ + + WM+
Sbjct: 93 SGKQRGPGDYLHFSPEQQYKP------DSSSGQGKALHDEG-----ADRKYTSPVYPWMQ 141
Query: 210 VKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLN 269
+ N G +G G R +T Q ELEKEFHFN+YLTR RR+EIA +L L
Sbjct: 142 -RMNSCAGAVYGSHGRRG-----RQTYTRYQTLELEKEFHFNRYLTRRRRIEIANALCLT 195
Query: 270 ETQVKIWFQNRRMKQKKREKEGLLPISPATPPGNDEKAE 308
E Q+KIWFQNRRMK KK K I+ P G D +A+
Sbjct: 196 ERQIKIWFQNRRMKWKKENK----LINSTQPSGEDSEAK 230
>gi|24497556 homeobox A7 [Homo sapiens]
Length = 230
Score = 87.4 bits (215), Expect = 2e-17
Identities = 67/210 (31%), Positives = 95/210 (45%), Gaps = 45/210 (21%)
Query: 120 SGGYPQCAPAVYSGNLSSPMVQHHHHHQGYAGGAVGSPQYIHHSYGQEHQSLALATYNNS 179
+G + P +Y N++SP+ Q GY GA +YG +L A+Y+ +
Sbjct: 44 AGAFASTVPGLY--NVNSPLYQSPFA-SGYGLGA--------DAYG----NLPCASYDQN 88
Query: 180 LSPLHASHQEACRSPASE------TSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVR 233
+ L + + E + + + WM+ K G R
Sbjct: 89 IPGLCSDLAKGACDKTDEGALHGAAEANFRIYPWMRSSGPDRKRG--------------R 134
Query: 234 TNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK---- 289
+T Q ELEKEFHFN+YLTR RR+EIA +L L E Q+KIWFQNRRMK KK K
Sbjct: 135 QTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDEGP 194
Query: 290 ------EGLLPISPATPPGNDEKAEESSEK 313
EG +P + AT + E+ E+
Sbjct: 195 TAAAAPEGAVPSAAATAAADKADEEDDDEE 224
>gi|11321638 homeobox C5 [Homo sapiens]
Length = 222
Score = 87.4 bits (215), Expect = 2e-17
Identities = 72/212 (33%), Positives = 94/212 (44%), Gaps = 21/212 (9%)
Query: 81 QTSGNLGVSYSHSSCGPSYGSQNFSAPYSPYALNQEADVSGGYPQCAPAVYSGNLSSPMV 140
QT GN G + + YG + S + P A + + G P + +
Sbjct: 22 QTCGNYGSASEVQASRYCYGGLDLSITFPPPAPSNS--LHGVDMAANPRAHPDRPACSAA 79
Query: 141 QHHHHHQGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHASHQEACRSPA--SET 198
H G A +P Y Q+ AL S + Q PA S+
Sbjct: 80 AAPGHAPGRDEAAPLNPGM----YSQKAARPALEERAKSSGEIK-EEQAQTGQPAGLSQP 134
Query: 199 SSPAQTFDWM-KVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRA 257
+P Q + WM K+ + GK RT++T Q ELEKEFHFN+YLTR
Sbjct: 135 PAPPQIYPWMTKLHMSHETDGKRS-----------RTSYTRYQTLELEKEFHFNRYLTRR 183
Query: 258 RRVEIAASLQLNETQVKIWFQNRRMKQKKREK 289
RR+EIA +L LNE Q+KIWFQNRRMK KK K
Sbjct: 184 RRIEIANNLCLNERQIKIWFQNRRMKWKKDSK 215
>gi|169636435 caudal type homeobox 2 [Homo sapiens]
Length = 313
Score = 87.0 bits (214), Expect = 2e-17
Identities = 76/249 (30%), Positives = 109/249 (43%), Gaps = 39/249 (15%)
Query: 91 SHSSCGPSYGSQNFSAP-------YSPYALNQEAD-VSGGYPQCAPAVYSGNLSSPMVQH 142
S S GPS+ + + AP Y+P A+ V+ G +PA G SSP H
Sbjct: 57 SAQSPGPSWPAA-YGAPLREDWNGYAPGGAAAAANAVAHGLNGGSPAAAMG-YSSPADYH 114
Query: 143 HHHHQGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPA 202
HHH HH + H + A + + L L+ + A+E SP
Sbjct: 115 PHHHPH------------HHPH---HPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSPG 159
Query: 203 ----QTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRAR 258
+WM+ P +G + R +T Q ELEKEFH+++Y+T R
Sbjct: 160 GQRRNLCEWMR----KPAQQSLGSQVKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRR 215
Query: 259 RVEIAASLQLNETQVKIWFQNRRMKQKKREKEGL------LPISPATPPGNDEKAEESSE 312
+ E+AA+L L+E QVKIWFQNRR K++K K+ L P P PP + +
Sbjct: 216 KAELAATLGLSERQVKIWFQNRRAKERKINKKKLQQQQQQQPPQPPPPPPQPPQPQPGPL 275
Query: 313 KSSSSPCVP 321
+S P P
Sbjct: 276 RSVPEPLSP 284
Score = 35.8 bits (81), Expect = 0.055
Identities = 14/23 (60%), Positives = 14/23 (60%)
Query: 64 PHHHHHHHHHHPQPATYQTSGNL 86
PHHH HHH HHP A SG L
Sbjct: 115 PHHHPHHHPHHPAAAPSCASGLL 137
Score = 28.9 bits (63), Expect = 6.8
Identities = 13/32 (40%), Positives = 15/32 (46%), Gaps = 11/32 (34%)
Query: 55 VGRGVQIGSP-----------HHHHHHHHHHP 75
V G+ GSP +H HHH HHHP
Sbjct: 92 VAHGLNGGSPAAAMGYSSPADYHPHHHPHHHP 123
>gi|89257348 homeo box HB9 [Homo sapiens]
Length = 401
Score = 87.0 bits (214), Expect = 2e-17
Identities = 63/160 (39%), Positives = 80/160 (50%), Gaps = 16/160 (10%)
Query: 146 HQGYAGGAVGSPQ----YIHHSYGQEHQSLA--LATYNNSLSPLHASHQEACRS-PASET 198
H G A G G P Y H YG + A LA + +LS + Q A + PA
Sbjct: 142 HPGGAQGGAGLPAQAALYGHPVYGYSAAAAAAALAGQHPALSYSYPQVQGAHPAHPADPI 201
Query: 199 SSPAQTFD---WMKVKR------NPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFH 249
A TF W++ P + LG+ RT FT++QL ELE +F
Sbjct: 202 KLGAGTFQLDQWLRASTAGMILPKMPDFNSQAQSNLLGKCRRPRTAFTSQQLLELEHQFK 261
Query: 250 FNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 289
NKYL+R +R E+A SL L ETQVKIWFQNRRMK K+ +K
Sbjct: 262 LNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKK 301
>gi|12056969 homeobox C8 [Homo sapiens]
Length = 242
Score = 87.0 bits (214), Expect = 2e-17
Identities = 68/216 (31%), Positives = 93/216 (43%), Gaps = 43/216 (19%)
Query: 130 VYSGNLSSPMVQHHHHHQG----YAGGAVGSPQYIHHSYGQEHQSLALATYNNSLSP--- 182
VY S+P QH HH + + + Y + A Y P
Sbjct: 39 VYGPGGSAPGFQHASHHVQDFFHHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQS 98
Query: 183 LHASHQEA-------CRSPAS-----------ETSSPAQTFDWMKVKRNPPKTGKVGEYG 224
L+ + QEA C+S A+ + SSP+ F WM+ ++G
Sbjct: 99 LYGAQQEASVVQYPDCKSSANTNSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSG------ 152
Query: 225 YLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQ 284
R ++ Q ELEKEF FN YLTR RR+E++ +L L E QVKIWFQNRRMK
Sbjct: 153 --------RQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKW 204
Query: 285 KKREKEGLLP----ISPATPPGNDEKAEESSEKSSS 316
KK + LP GN+E+ +E EK +
Sbjct: 205 KKENNKDKLPGARDEEKVEEEGNEEEEKEEEEKEEN 240
>gi|4504469 homeobox B5 [Homo sapiens]
Length = 269
Score = 86.7 bits (213), Expect = 3e-17
Identities = 53/117 (45%), Positives = 66/117 (56%), Gaps = 9/117 (7%)
Query: 174 ATYNNSLSPLHASHQEACRSPASETSSPAQTFDWM-KVKRNPPKTGKVGEYGYLGQPNAV 232
A+ +S S A + S A+ Q F WM K+ + TG G+
Sbjct: 146 ASQLSSPSLARAQPEPMATSTAAPEGQTPQIFPWMRKLHISHDMTGPDGK--------RA 197
Query: 233 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 289
RT +T Q ELEKEFHFN+YLTR RR+EIA +L L+E Q+KIWFQNRRMK KK K
Sbjct: 198 RTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 254
>gi|23503237 homeobox B6 [Homo sapiens]
Length = 224
Score = 85.5 bits (210), Expect = 6e-17
Identities = 67/216 (31%), Positives = 91/216 (42%), Gaps = 36/216 (16%)
Query: 102 QNFSAPYSPYALNQEA--------DVSGGYPQCAPAVYSGNLSSPMVQHHHHHQGYAGGA 153
+++ APY P + GGY + AP Y +P GA
Sbjct: 37 RHYPAPYGPGPGQDKGFATSSYYPPAGGGYGRAAPCDYG---PAPAFYREKESACALSGA 93
Query: 154 VGSPQYIHHSYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQTFDWMKVKRN 213
P + H + S + ++ C +P + WM+ + N
Sbjct: 94 DEQPPF--------HPEPRKSDCAQDKSVFGETEEQKCSTPV---------YPWMQ-RMN 135
Query: 214 PPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQV 273
+ G G G R +T Q ELEKEFH+N+YLTR RR+EIA +L L E Q+
Sbjct: 136 SCNSSSFGPSGRRG-----RQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQI 190
Query: 274 KIWFQNRRMKQKKREKEGLLPISPATPPGNDEKAEE 309
KIWFQNRRMK KK K LL S + +EK E
Sbjct: 191 KIWFQNRRMKWKKESK--LLSASQLSAEEEEEKQAE 224
>gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]
Length = 283
Score = 84.7 bits (208), Expect = 1e-16
Identities = 52/129 (40%), Positives = 65/129 (50%), Gaps = 7/129 (5%)
Query: 205 FDWMKVKRNPPKTGKVGEYGYLGQPNA---VRTNFTTKQLTELEKEFHFNKYLTRARRVE 261
F WMK + G+ Y +P RT +T QL ELEKEF FNKY++R RRVE
Sbjct: 119 FPWMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVE 178
Query: 262 IAASLQLNETQVKIWFQNRRMKQKKREKE----GLLPISPATPPGNDEKAEESSEKSSSS 317
+A L L E +KIWFQNRRMK KK E + G + A S E+ +
Sbjct: 179 LAVMLNLTERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAEPEQDCAVTSGEELLAL 238
Query: 318 PCVPSPGSS 326
P P PG +
Sbjct: 239 PPPPPPGGA 247
>gi|23097236 homeobox A9 [Homo sapiens]
Length = 272
Score = 84.7 bits (208), Expect = 1e-16
Identities = 72/228 (31%), Positives = 96/228 (42%), Gaps = 46/228 (20%)
Query: 65 HHHHHHHHHHPQPATYQTSGNLGVSYSHSSCGPSYGSQNFSAPYS--PYALNQEADVSGG 122
HHHHHH + HPQ + + Y S P+ G+ +F+ S PY + E +S
Sbjct: 84 HHHHHHPYVHPQAPVAAAAPD--GRYMRSWLEPTPGALSFAGLPSSRPYGIKPEP-LSAR 140
Query: 123 YPQCAPAVYSGNLSSPMVQHHHHHQGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSLSP 182
C P + + LS A GSP E + S
Sbjct: 141 RGDC-PTLDTHTLS------------LTDYACGSPPVDREKQPSE----------GAFSE 177
Query: 183 LHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLT 242
+A ++ P + ++PA +W+ + K R +T Q
Sbjct: 178 NNAENESGGDKPPIDPNNPAA--NWLHARSTRKK----------------RCPYTKHQTL 219
Query: 243 ELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKE 290
ELEKEF FN YLTR RR E+A L L E QVKIWFQNRRMK KK K+
Sbjct: 220 ELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKD 267
>gi|15029506 homeobox D8 [Homo sapiens]
Length = 290
Score = 84.3 bits (207), Expect = 1e-16
Identities = 46/113 (40%), Positives = 62/113 (54%), Gaps = 13/113 (11%)
Query: 196 SETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLT 255
+++SSP+Q F WM+ + P + R ++ Q ELEKEF FN YLT
Sbjct: 177 NQSSSPSQMFPWMRPQAAPGR-------------RRGRQTYSRFQTLELEKEFLFNPYLT 223
Query: 256 RARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGNDEKAE 308
R RR+E++ +L L E QVKIWFQNRRMK KK + P+S + K E
Sbjct: 224 RKRRIEVSHALALTERQVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETKKE 276
>gi|24497515 homeobox A3 isoform b [Homo sapiens]
Length = 285
Score = 84.3 bits (207), Expect = 1e-16
Identities = 43/70 (61%), Positives = 51/70 (72%), Gaps = 1/70 (1%)
Query: 233 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK-EG 291
RT +T+ QL ELEKEFHFN+YL R RRVE+A L L E Q+KIWFQNRRMK KK +K +G
Sbjct: 37 RTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKG 96
Query: 292 LLPISPATPP 301
+L S P
Sbjct: 97 MLTSSGGQSP 106
>gi|85068580 homeobox B7 [Homo sapiens]
Length = 217
Score = 84.0 bits (206), Expect = 2e-16
Identities = 65/226 (28%), Positives = 94/226 (41%), Gaps = 39/226 (17%)
Query: 108 YSPYALNQEADVSGGYPQCAPAVYSGNLSSPM------VQHHHHHQG-YAGGAVGSPQYI 160
+S Y + +G +P+ ++ N P QG Y GG + Q
Sbjct: 11 FSKYPASSSVFATGAFPEQTSCAFASNPQRPGYGAGSGASFAASMQGLYPGGGGMAGQSA 70
Query: 161 HHSYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQTFD-------------W 207
Y + L +++N +P + C +++ + + D W
Sbjct: 71 AGVYAAGY-GLEPSSFNMHCAPFEQNLSGVCPGDSAKAAGAKEQRDSDLAAESNFRIYPW 129
Query: 208 MKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQ 267
M+ K G R +T Q ELEKEFH+N+YLTR RR+EIA +L
Sbjct: 130 MRSSGTDRKRG--------------RQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLC 175
Query: 268 LNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGNDEKAEESSEK 313
L E Q+KIWFQNRRMK KK K P T + +AEE E+
Sbjct: 176 LTERQIKIWFQNRRMKWKKENKTA----GPGTTGQDRAEAEEEEEE 217
>gi|84570137 homeobox B3 [Homo sapiens]
Length = 431
Score = 84.0 bits (206), Expect = 2e-16
Identities = 49/103 (47%), Positives = 59/103 (57%), Gaps = 14/103 (13%)
Query: 233 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGL 292
RT +T+ QL ELEKEFHFN+YL R RRVE+A L L+E Q+KIWFQNRRMK KK +K
Sbjct: 192 RTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAKG 251
Query: 293 LPISPATPPGNDEKAEESSEKSSSSPCVPSPGSSTSDTLTTSH 335
L S P + SP P P ST+ + H
Sbjct: 252 LASSSGGP------------SPAGSP--PQPMQSTAGFMNALH 280
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.126 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,120,148
Number of Sequences: 37866
Number of extensions: 774838
Number of successful extensions: 5740
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 396
Number of HSP's successfully gapped in prelim test: 80
Number of HSP's that attempted gapping in prelim test: 3331
Number of HSP's gapped (non-prelim): 1419
length of query: 335
length of database: 18,247,518
effective HSP length: 103
effective length of query: 232
effective length of database: 14,347,320
effective search space: 3328578240
effective search space used: 3328578240
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.