Guide to the Human Genome
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Name: STAT3 Sequence: fasta or formatted (722aa) NCBI GI: 47458820
Description:

signal transducer and activator of transcription 3 isoform 3

Referenced in:

Non-Receptor Tyrosine Kinase Pathways

Other entries for this name:
alt prot [769aa] signal transducer and activator of transcription 3 isoform 2
alt prot [770aa] signal transducer and activator of transcription 3 isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.8         42           2
 C cysteine            1.7         12           1
 D aspartate           4.2         30           2
 E glutamate           7.5         54           2
 F phenylalanine       3.9         28           2
 G glycine             4.7         34           2
 H histidine           1.8         13           1
 I isoleucine          5.7         41           2
 K lysine              6.6         48           2
 L leucine            10.7         77           2
 M methionine          3.2         23           1
 N asparagine          4.8         35           2
 P proline             4.2         30           2
 Q glutamine           8.0         58           2
 R arginine            4.7         34           2
 S serine              6.1         44           2
 T threonine           5.5         40           2
 V valine              5.8         42           3
 W tryptophan          2.2         16           1
 Y tyrosine            2.9         21           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   signal transducer and activator of transcription 3 i... 
STAT3                 0.989   signal transducer and activator of transcription 3 i...
STAT3                 0.985   signal transducer and activator of transcription 3 i...
STAT1                 0.523   signal transducer and activator of transcription 1 is...
STAT1                 0.523   signal transducer and activator of transcription 1 i...
STAT4                 0.465   signal transducer and activator of transcription 4 [H...
STAT2                 0.326   signal transducer and activator of transcription 2 [H...
STAT5B                0.203   signal transducer and activator of transcription 5B ...
STAT5A                0.201   signal transducer and activator of transcription 5A ...
STAT6                 0.116   signal transducer and activator of transcription 6 [...
NUMA1                 0.014   nuclear mitotic apparatus protein 1 
TPR                   0.014   nuclear pore complex-associated protein TPR 
MYH10                 0.013   myosin, heavy polypeptide 10, non-muscle 
CENPE                 0.012   centromere protein E 
MYH9                  0.012   myosin, heavy polypeptide 9, non-muscle 
EEA1                  0.010   early endosome antigen 1, 162kD 
PPFIBP1               0.010   PTPRF interacting protein binding protein 1 isoform ...
MACF1                 0.010   microfilament and actin filament cross-linker protei...
MAP1A                 0.010   microtubule-associated protein 1A 
CROCC                 0.010   ciliary rootlet coiled-coil 
GOLGA2                0.010   Golgi autoantigen, golgin subfamily a, 2 
WDR87                 0.010   NYD-SP11 protein 
AKAP9                 0.010   A-kinase anchor protein 9 isoform 3 
RPGRIP1               0.010   retinitis pigmentosa GTPase regulator interacting p...
KIF20B                0.010   M-phase phosphoprotein 1 
PHLDB3                0.010   pleckstrin homology-like domain, family B, member 3...
CCDC30                0.009   coiled-coil domain containing 30 
TNIP1                 0.009   TNFAIP3 interacting protein 1 
MACF1                 0.009   microfilament and actin filament cross-linker protei...
MYH11                 0.009   smooth muscle myosin heavy chain 11 isoform SM1A [Ho...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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