Guide to the Human Genome
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Search of human proteins with 13236561

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13236561 ATPase family, AAA domain containing 4 [Homo
sapiens]
         (103 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13236561 ATPase family, AAA domain containing 4 [Homo sapiens]     215   5e-57
gi|28557711 proline rich 15 [Homo sapiens]                             42   8e-05
gi|61743954 AHNAK nucleoprotein isoform 1 [Homo sapiens]               31   0.24 
gi|109637784 GLIS family zinc finger 3 isoform a [Homo sapiens]        28   1.2  
gi|187960059 syndecan 3 [Homo sapiens]                                 28   1.2  
gi|109637782 GLIS family zinc finger 3 isoform b [Homo sapiens]        28   1.2  
gi|110349719 titin isoform N2-A [Homo sapiens]                         28   1.6  
gi|47519913 5-hydroxytryptamine receptor 3 subunit E [Homo sapiens]    28   1.6  
gi|40806187 ADAM metallopeptidase with thrombospondin type 1 mot...    28   2.0  
gi|33356148 formin-like 1 [Homo sapiens]                               28   2.0  
gi|93587342 voltage-gated sodium channel type 4 alpha [Homo sapi...    27   2.6  
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         27   2.6  
gi|24497601 endothelial differentiation-related factor 1 isoform...    27   3.5  
gi|4503453 endothelial differentiation-related factor 1 isoform ...    27   3.5  
gi|98986461 neurogenic differentiation 2 [Homo sapiens]                26   5.9  
gi|31542760 hypothetical protein LOC220108 [Homo sapiens]              26   5.9  
gi|8923271 coiled-coil domain containing 49 [Homo sapiens]             26   5.9  
gi|4503009 carboxypeptidase E preproprotein [Homo sapiens]             26   7.7  
gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]                  26   7.7  

>gi|13236561 ATPase family, AAA domain containing 4 [Homo sapiens]
          Length = 103

 Score =  215 bits (548), Expect = 5e-57
 Identities = 103/103 (100%), Positives = 103/103 (100%)

Query: 1   MTTEIGWWKLTFLRKKKSTPKVLYEIPDTYAQTEGDAEPPRPDAGGPNSDFNTRLEKIVD 60
           MTTEIGWWKLTFLRKKKSTPKVLYEIPDTYAQTEGDAEPPRPDAGGPNSDFNTRLEKIVD
Sbjct: 1   MTTEIGWWKLTFLRKKKSTPKVLYEIPDTYAQTEGDAEPPRPDAGGPNSDFNTRLEKIVD 60

Query: 61  KSTKGKHVKVSNSGRFKEKKKVRATLAENPNLFDDHEEGRSSK 103
           KSTKGKHVKVSNSGRFKEKKKVRATLAENPNLFDDHEEGRSSK
Sbjct: 61  KSTKGKHVKVSNSGRFKEKKKVRATLAENPNLFDDHEEGRSSK 103


>gi|28557711 proline rich 15 [Homo sapiens]
          Length = 129

 Score = 42.4 bits (98), Expect = 8e-05
 Identities = 35/101 (34%), Positives = 49/101 (48%), Gaps = 27/101 (26%)

Query: 7   WWK-LTFLRKKKSTPKVLYEIPDTYAQTEGDAEPPRPDAGGPNSDFNT------------ 53
           WWK LT  RKK     V   +P       G+  PP P    P+ D+ +            
Sbjct: 13  WWKSLTNSRKKSKEAAV--GVPPPAQPAPGEPTPPAP----PSPDWTSSSRENQHPNLLG 66

Query: 54  ------RLEKIV-DKS-TKGKHVKVSNSGRFKEKKKVRATL 86
                 + +K+  DKS +  +++K+S SGRFKEK+KVRATL
Sbjct: 67  GAGEPPKPDKLYGDKSGSSRRNLKISRSGRFKEKRKVRATL 107


>gi|61743954 AHNAK nucleoprotein isoform 1 [Homo sapiens]
          Length = 5890

 Score = 30.8 bits (68), Expect = 0.24
 Identities = 14/34 (41%), Positives = 18/34 (52%)

Query: 20   PKVLYEIPDTYAQTEGDAEPPRPDAGGPNSDFNT 53
            PKV  ++  T  + EGD + P  D  GP  D NT
Sbjct: 4733 PKVKGDVDVTLPKVEGDLKGPEADIKGPKVDINT 4766



 Score = 28.5 bits (62), Expect = 1.2
 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 6/84 (7%)

Query: 20   PKVLYEIPDTYAQTEGDAEPPRPDAGGPNSDFNTRLEKIVDKSTKGKHVKVSNSGRFKEK 79
            PKV  ++  +  + EGD + P  D  GP+ D +T      D + +G   K+        +
Sbjct: 4397 PKVKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDT-----PDVNIEGPEGKLKGPKFKMPE 4451

Query: 80   KKVRATLAENPNLFDDHEEGRSSK 103
              ++A     P+ FD H +G   K
Sbjct: 4452 MNIKAPKISMPD-FDLHLKGPKVK 4474



 Score = 26.9 bits (58), Expect = 3.5
 Identities = 12/33 (36%), Positives = 17/33 (51%)

Query: 20   PKVLYEIPDTYAQTEGDAEPPRPDAGGPNSDFN 52
            PKV  ++  +  + EGD + P  D  GP  D N
Sbjct: 2591 PKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIN 2623



 Score = 26.6 bits (57), Expect = 4.5
 Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 5/44 (11%)

Query: 20   PKVLYEIPDTYAQTEGDAEPPRPDAGGPN-----SDFNTRLEKI 58
            PKV  E   T  + EGD + P+ D   P+      D+N ++ KI
Sbjct: 958  PKVKGEYDMTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKI 1001



 Score = 26.6 bits (57), Expect = 4.5
 Identities = 12/33 (36%), Positives = 17/33 (51%)

Query: 20   PKVLYEIPDTYAQTEGDAEPPRPDAGGPNSDFN 52
            PKV  ++  +  + EGD + P  D  GP  D N
Sbjct: 3555 PKVKGDVDISLPKLEGDLKGPEVDIKGPKVDIN 3587



 Score = 26.6 bits (57), Expect = 4.5
 Identities = 12/33 (36%), Positives = 17/33 (51%)

Query: 20   PKVLYEIPDTYAQTEGDAEPPRPDAGGPNSDFN 52
            PKV  ++  +  + EGD + P  D  GP  D N
Sbjct: 3757 PKVKGDVDVSLPKMEGDLKGPEVDIKGPKVDIN 3789


>gi|109637784 GLIS family zinc finger 3 isoform a [Homo sapiens]
          Length = 930

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 13/40 (32%), Positives = 24/40 (60%)

Query: 56  EKIVDKSTKGKHVKVSNSGRFKEKKKVRATLAENPNLFDD 95
           ++  D S+  KHVK  +S   + +KK+R++   +P+L  D
Sbjct: 636 KRYTDPSSLRKHVKAHSSKEQQARKKLRSSTELHPDLLTD 675


>gi|187960059 syndecan 3 [Homo sapiens]
          Length = 442

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 16/47 (34%), Positives = 23/47 (48%), Gaps = 1/47 (2%)

Query: 27  PDTYAQTEGDAEPPRPDAGGPNSDFNTRLEKIVDKSTKGKHVKVSNS 73
           P+T+  T  D EP  P +GGP+ DF    E+     T  + V V  +
Sbjct: 294 PETFLTTIRD-EPEVPVSGGPSGDFELPEEETTQPDTANEVVAVGGA 339


>gi|109637782 GLIS family zinc finger 3 isoform b [Homo sapiens]
          Length = 775

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 13/40 (32%), Positives = 24/40 (60%)

Query: 56  EKIVDKSTKGKHVKVSNSGRFKEKKKVRATLAENPNLFDD 95
           ++  D S+  KHVK  +S   + +KK+R++   +P+L  D
Sbjct: 481 KRYTDPSSLRKHVKAHSSKEQQARKKLRSSTELHPDLLTD 520


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 23/85 (27%), Positives = 38/85 (44%), Gaps = 7/85 (8%)

Query: 16   KKSTPKVLYEIPDTYAQTEGDAEPPRPDAGGPNSDFNTRLEKIVDKSTKGKHVKVSNSGR 75
            KK   KV+ +  +   + E   +PP P    P      +  +I+D S+K + VK+    R
Sbjct: 8990 KKDAKKVVAKPKEMTPREEIVKKPPPPTTLIP-----AKAPEIIDVSSKAEEVKIMTITR 9044

Query: 76   FKEKKKVRATLAENPNLFDDHEEGR 100
             KE +K +  + E       H+E R
Sbjct: 9045 KKEVQKEKEAVYEKKQAV--HKEKR 9067


>gi|47519913 5-hydroxytryptamine receptor 3 subunit E [Homo sapiens]
          Length = 471

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 14/35 (40%), Positives = 20/35 (57%)

Query: 59  VDKSTKGKHVKVSNSGRFKEKKKVRATLAENPNLF 93
           VDK+ KG    VSN GR + KK ++     N ++F
Sbjct: 148 VDKTPKGLTAYVSNEGRIRYKKPMKVDSICNLDIF 182


>gi|40806187 ADAM metallopeptidase with thrombospondin type 1 motif,
           18 preproprotein [Homo sapiens]
          Length = 1221

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 20/58 (34%), Positives = 25/58 (43%), Gaps = 4/58 (6%)

Query: 14  RKKKSTPKVLYEIPDTYAQTE--GDAEPPRPDAGGPNSDFNTRLEKIVDKSTKGKHVK 69
           R+KK  PK   E  DTY + +  G +  PR  AG      N     + DK    KH K
Sbjct: 256 RRKKYAPKPPTE--DTYLRFDEYGSSGRPRRSAGKSQKGLNVETLVVADKKMVEKHGK 311


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 2/72 (2%)

Query: 2   TTEIGWWKLTFLRKKKSTPKVLYEIPDTYAQTEGDAEPPRPDAGGPNSDFNTRLEKIVDK 61
           T  IGW +  FL ++     VL E    +AQ     +    D G  NS+ N  LE+ V+ 
Sbjct: 130 TNHIGWVQ-EFLNEENRGLDVLLEYL-AFAQCSVTYDMESTDNGASNSEKNKPLEQSVED 187

Query: 62  STKGKHVKVSNS 73
            +KG    V  S
Sbjct: 188 LSKGPPSSVPKS 199


>gi|93587342 voltage-gated sodium channel type 4 alpha [Homo sapiens]
          Length = 1836

 Score = 27.3 bits (59), Expect = 2.6
 Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 1/79 (1%)

Query: 25   EIPDTYAQTEGDAEPPRPDAGGPNSDFNTRLEKIVDKSTKGKHVKVSNSGRFKEKKKVRA 84
            E  DT+++ E   +PP+P   G +S  +T   K  ++  + +  + +  G   E+    A
Sbjct: 939  EETDTFSEPEDSKKPPQPLYDGNSSVCSTADYKPPEEDPE-EQAEENPEGEQPEECFTEA 997

Query: 85   TLAENPNLFDDHEEGRSSK 103
             +   P L+ D  +GR  K
Sbjct: 998  CVQRWPCLYVDISQGRGKK 1016


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 27.3 bits (59), Expect = 2.6
 Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 1/57 (1%)

Query: 34  EGDAEPPRPDAGGPNSDFNTRLEKIVDKSTKGKHVKVSNSGRFKEKKKVRATLAENP 90
           EG AEP  P   GP+S+       +V KS +G+  K  N  R     +   TL  +P
Sbjct: 921 EGGAEPKDPPPPGPHSEDLKVPPGVVRKSRRGRRRKY-NPTRNSNSSRQDITLEPSP 976


>gi|24497601 endothelial differentiation-related factor 1 isoform
           beta [Homo sapiens]
          Length = 139

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 31/112 (27%), Positives = 47/112 (41%), Gaps = 14/112 (12%)

Query: 4   EIGWWKLTFLRKKKSTP-KVLYEIPDTYAQTEG-DAEPPRPDAGGPNSDFN-TRLEKIVD 60
           E  W  +T LRKK  T  +   +     AQ  G D E  +  A G N   + T+    +D
Sbjct: 3   ESDWDTVTVLRKKGPTAAQAKSKQAILAAQRRGEDVETSKKWAAGQNKQHSITKNTAKLD 62

Query: 61  KSTKGKHV--------KVSNSGRFKE---KKKVRATLAENPNLFDDHEEGRS 101
           + T+  H         KV   GR  +   +K +   + E P +  D+E GR+
Sbjct: 63  RETEELHHDRVTLEVGKVIQQGRQSKGLTQKDLATKINEKPQVIADYESGRA 114


>gi|4503453 endothelial differentiation-related factor 1 isoform
           alpha [Homo sapiens]
          Length = 148

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 31/112 (27%), Positives = 47/112 (41%), Gaps = 14/112 (12%)

Query: 4   EIGWWKLTFLRKKKSTP-KVLYEIPDTYAQTEG-DAEPPRPDAGGPNSDFN-TRLEKIVD 60
           E  W  +T LRKK  T  +   +     AQ  G D E  +  A G N   + T+    +D
Sbjct: 3   ESDWDTVTVLRKKGPTAAQAKSKQAILAAQRRGEDVETSKKWAAGQNKQHSITKNTAKLD 62

Query: 61  KSTKGKHV--------KVSNSGRFKE---KKKVRATLAENPNLFDDHEEGRS 101
           + T+  H         KV   GR  +   +K +   + E P +  D+E GR+
Sbjct: 63  RETEELHHDRVTLEVGKVIQQGRQSKGLTQKDLATKINEKPQVIADYESGRA 114


>gi|98986461 neurogenic differentiation 2 [Homo sapiens]
          Length = 382

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 20/71 (28%), Positives = 29/71 (40%), Gaps = 14/71 (19%)

Query: 18 STPKVLYEIP----------DTYAQTEGDAEPPRPDAGGPNSDFNTRLEKIV----DKST 63
          S P +L ++P          D     +GDA PP P A GP +    R  K V    ++ T
Sbjct: 7  SEPGLLSDVPKFASWGDGEDDEPRSDKGDAPPPPPPAPGPGAPGPARAAKPVPLRGEEGT 66

Query: 64 KGKHVKVSNSG 74
          +    +V   G
Sbjct: 67 EATLAEVKEEG 77


>gi|31542760 hypothetical protein LOC220108 [Homo sapiens]
          Length = 582

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 20/70 (28%), Positives = 26/70 (37%), Gaps = 20/70 (28%)

Query: 1   MTTEIGWWKLTFLRKKKS----TPKVLYEIPDTYA----------------QTEGDAEPP 40
           +TTE  W  L F  K+ S    T +     P T                  QT+GD  PP
Sbjct: 507 VTTEASWASLPFFTKRSSSSSATARAAPPAPSTSTLTDSSPQLPCDTPKVKQTDGDMPPP 566

Query: 41  RPDAGGPNSD 50
              AG  ++D
Sbjct: 567 PGSAGPGDND 576


>gi|8923271 coiled-coil domain containing 49 [Homo sapiens]
          Length = 425

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 14/51 (27%), Positives = 28/51 (54%), Gaps = 1/51 (1%)

Query: 54  RLEKIVDKSTKGKHVKVSNSGRFKEKK-KVRATLAENPNLFDDHEEGRSSK 103
           ++++++  S + K  K     + K KK K R++ ++  +  D+H  GRS K
Sbjct: 162 KIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSEDEHSAGRSQK 212


>gi|4503009 carboxypeptidase E preproprotein [Homo sapiens]
          Length = 476

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 10/20 (50%), Positives = 15/20 (75%)

Query: 45  GGPNSDFNTRLEKIVDKSTK 64
           GGPN+     ++KIVD++TK
Sbjct: 205 GGPNNHLLKNMKKIVDQNTK 224


>gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]
          Length = 1726

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 16/52 (30%), Positives = 25/52 (48%)

Query: 9   KLTFLRKKKSTPKVLYEIPDTYAQTEGDAEPPRPDAGGPNSDFNTRLEKIVD 60
           K T LR +K     L+E    Y   +  A+P +P A G  +   T +E++ D
Sbjct: 402 KWTQLRIRKENLTRLFEKMQAYQYEQISADPDKPLADGIRALDTTDMERLKD 453


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.129    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,591,580
Number of Sequences: 37866
Number of extensions: 201623
Number of successful extensions: 509
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 467
Number of HSP's gapped (non-prelim): 52
length of query: 103
length of database: 18,247,518
effective HSP length: 74
effective length of query: 29
effective length of database: 15,445,434
effective search space: 447917586
effective search space used: 447917586
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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