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Search of human proteins with 39752683
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|39752683 prestin isoform a [Homo sapiens]
(744 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|39752683 prestin isoform a [Homo sapiens] 1462 0.0
gi|45827800 prestin isoform b [Homo sapiens] 1337 0.0
gi|45827802 prestin isoform c [Homo sapiens] 987 0.0
gi|45827804 prestin isoform d [Homo sapiens] 642 0.0
gi|94721257 solute carrier family 26, member 6 isoform 3 [Homo s... 564 e-161
gi|94721253 solute carrier family 26, member 6 isoform 1 [Homo s... 560 e-159
gi|94721259 solute carrier family 26, member 6 isoform 4 [Homo s... 559 e-159
gi|94721255 solute carrier family 26, member 6 isoform 2 [Homo s... 558 e-159
gi|4505697 pendrin [Homo sapiens] 538 e-153
gi|4557535 solute carrier family 26, member 3 [Homo sapiens] 513 e-145
gi|16418413 solute carrier family 26, member 9 isoform a [Homo s... 492 e-139
gi|217272867 solute carrier family 26, member 9 isoform b [Homo ... 492 e-139
gi|100913030 solute carrier family 26 member 2 [Homo sapiens] 461 e-130
gi|47131207 solute carrier family 26, member 1 isoform a [Homo s... 414 e-115
gi|20336272 solute carrier family 26, member 1 isoform a [Homo s... 414 e-115
gi|16306483 solute carrier family 26, member 7 isoform a [Homo s... 300 2e-81
gi|20336282 solute carrier family 26, member 7 isoform b [Homo s... 300 2e-81
gi|16418457 solute carrier family 26, member 8 isoform a [Homo s... 282 7e-76
gi|65506789 solute carrier family 26, member 10 [Homo sapiens] 258 1e-68
gi|217272870 solute carrier family 26, member 9 isoform c [Homo ... 256 4e-68
gi|85540447 solute carrier family 26, member 11 [Homo sapiens] 186 5e-47
gi|20336285 solute carrier family 26, member 8 isoform b [Homo s... 171 3e-42
gi|20336274 solute carrier family 26, member 1 isoform b [Homo s... 109 8e-24
gi|32401433 G protein-coupled receptor 142 [Homo sapiens] 31 4.8
gi|18379366 zinc metallopeptidase STE24 [Homo sapiens] 30 8.1
gi|45827778 reticulon 1 isoform B [Homo sapiens] 30 8.1
gi|45827776 reticulon 1 isoform C [Homo sapiens] 30 8.1
gi|10863935 reticulon 1 isoform A [Homo sapiens] 30 8.1
>gi|39752683 prestin isoform a [Homo sapiens]
Length = 744
Score = 1462 bits (3784), Expect = 0.0
Identities = 744/744 (100%), Positives = 744/744 (100%)
Query: 1 MDHAEENEILAATQRYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNI 60
MDHAEENEILAATQRYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNI
Sbjct: 1 MDHAEENEILAATQRYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNI 60
Query: 61 IYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPV 120
IYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPV
Sbjct: 61 IYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPV 120
Query: 121 IMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAM 180
IMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAM
Sbjct: 121 IMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAM 180
Query: 181 SVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGI 240
SVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGI
Sbjct: 181 SVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGI 240
Query: 241 FSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMG 300
FSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMG
Sbjct: 241 FSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMG 300
Query: 301 TGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKT 360
TGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKT
Sbjct: 301 TGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKT 360
Query: 361 LANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLM 420
LANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLM
Sbjct: 361 LANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLM 420
Query: 421 ILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSL 480
ILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSL
Sbjct: 421 ILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSL 480
Query: 481 FLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQI 540
FLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQI
Sbjct: 481 FLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQI 540
Query: 541 NAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMANATVVKADAEVD 600
NAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMANATVVKADAEVD
Sbjct: 541 NAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMANATVVKADAEVD 600
Query: 601 GEDATKPEEEDGEVKYPPIVIKSTFPEEMQRFMPPGDNVHTVILDFTQVNFIDSVGVKTL 660
GEDATKPEEEDGEVKYPPIVIKSTFPEEMQRFMPPGDNVHTVILDFTQVNFIDSVGVKTL
Sbjct: 601 GEDATKPEEEDGEVKYPPIVIKSTFPEEMQRFMPPGDNVHTVILDFTQVNFIDSVGVKTL 660
Query: 661 AGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFFENPALWELLFHSIHDAVLGSQLREALA 720
AGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFFENPALWELLFHSIHDAVLGSQLREALA
Sbjct: 661 AGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFFENPALWELLFHSIHDAVLGSQLREALA 720
Query: 721 EQEASAPPSQEDLEPNATPATPEA 744
EQEASAPPSQEDLEPNATPATPEA
Sbjct: 721 EQEASAPPSQEDLEPNATPATPEA 744
>gi|45827800 prestin isoform b [Homo sapiens]
Length = 685
Score = 1337 bits (3459), Expect = 0.0
Identities = 681/681 (100%), Positives = 681/681 (100%)
Query: 1 MDHAEENEILAATQRYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNI 60
MDHAEENEILAATQRYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNI
Sbjct: 1 MDHAEENEILAATQRYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNI 60
Query: 61 IYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPV 120
IYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPV
Sbjct: 61 IYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPV 120
Query: 121 IMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAM 180
IMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAM
Sbjct: 121 IMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAM 180
Query: 181 SVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGI 240
SVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGI
Sbjct: 181 SVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGI 240
Query: 241 FSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMG 300
FSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMG
Sbjct: 241 FSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMG 300
Query: 301 TGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKT 360
TGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKT
Sbjct: 301 TGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKT 360
Query: 361 LANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLM 420
LANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLM
Sbjct: 361 LANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLM 420
Query: 421 ILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSL 480
ILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSL
Sbjct: 421 ILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSL 480
Query: 481 FLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQI 540
FLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQI
Sbjct: 481 FLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQI 540
Query: 541 NAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMANATVVKADAEVD 600
NAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMANATVVKADAEVD
Sbjct: 541 NAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMANATVVKADAEVD 600
Query: 601 GEDATKPEEEDGEVKYPPIVIKSTFPEEMQRFMPPGDNVHTVILDFTQVNFIDSVGVKTL 660
GEDATKPEEEDGEVKYPPIVIKSTFPEEMQRFMPPGDNVHTVILDFTQVNFIDSVGVKTL
Sbjct: 601 GEDATKPEEEDGEVKYPPIVIKSTFPEEMQRFMPPGDNVHTVILDFTQVNFIDSVGVKTL 660
Query: 661 AGIVKEYGDVGIYVYLAGCSA 681
AGIVKEYGDVGIYVYLAGCSA
Sbjct: 661 AGIVKEYGDVGIYVYLAGCSA 681
>gi|45827802 prestin isoform c [Homo sapiens]
Length = 516
Score = 987 bits (2552), Expect = 0.0
Identities = 505/505 (100%), Positives = 505/505 (100%)
Query: 1 MDHAEENEILAATQRYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNI 60
MDHAEENEILAATQRYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNI
Sbjct: 1 MDHAEENEILAATQRYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNI 60
Query: 61 IYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPV 120
IYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPV
Sbjct: 61 IYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPV 120
Query: 121 IMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAM 180
IMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAM
Sbjct: 121 IMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAM 180
Query: 181 SVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGI 240
SVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGI
Sbjct: 181 SVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGI 240
Query: 241 FSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMG 300
FSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMG
Sbjct: 241 FSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMG 300
Query: 301 TGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKT 360
TGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKT
Sbjct: 301 TGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKT 360
Query: 361 LANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLM 420
LANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLM
Sbjct: 361 LANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLM 420
Query: 421 ILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSL 480
ILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSL
Sbjct: 421 ILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSL 480
Query: 481 FLGLDYGLITAVIIALLTVIYRTQS 505
FLGLDYGLITAVIIALLTVIYRTQS
Sbjct: 481 FLGLDYGLITAVIIALLTVIYRTQS 505
>gi|45827804 prestin isoform d [Homo sapiens]
Length = 335
Score = 642 bits (1656), Expect = 0.0
Identities = 324/324 (100%), Positives = 324/324 (100%)
Query: 1 MDHAEENEILAATQRYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNI 60
MDHAEENEILAATQRYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNI
Sbjct: 1 MDHAEENEILAATQRYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNI 60
Query: 61 IYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPV 120
IYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPV
Sbjct: 61 IYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPV 120
Query: 121 IMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAM 180
IMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAM
Sbjct: 121 IMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAM 180
Query: 181 SVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGI 240
SVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGI
Sbjct: 181 SVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGI 240
Query: 241 FSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMG 300
FSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMG
Sbjct: 241 FSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMG 300
Query: 301 TGISAGFNLKESYNVDVVGTLPLG 324
TGISAGFNLKESYNVDVVGTLPLG
Sbjct: 301 TGISAGFNLKESYNVDVVGTLPLG 324
>gi|94721257 solute carrier family 26, member 6 isoform 3 [Homo
sapiens]
Length = 740
Score = 564 bits (1454), Expect = e-161
Identities = 302/723 (41%), Positives = 451/723 (62%), Gaps = 38/723 (5%)
Query: 9 ILAATQR-------YYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNII 61
+L+ATQ Y++ERP+ + L+E L P + + + C+ + ++
Sbjct: 15 LLSATQAMDLRRRDYHMERPLLNQEHLEE-LGRWGSAPRT--HQWRTWLQCSRARAYALL 71
Query: 62 YMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVI 121
LP+ WLP Y ++++LGDL+SG+S ++QLPQGLA+A+LA +PP+FGLYSSFYPV
Sbjct: 72 LQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFYPVF 131
Query: 122 MYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMS 181
+Y GTSRHIS+G FAV+S+M+G V L P + +N T ARDA RV+VA +
Sbjct: 132 IYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQALN-DSMINET----ARDAARVQVAST 186
Query: 182 VTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIF 241
+++L G+ Q LG+ FGFV YL+EPLVRG+TTAAAV VF S LKY+FG+ +SG
Sbjct: 187 LSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPL 246
Query: 242 SVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGT 301
S++Y+ + V + V ++ + +L+ K N++ +++LP PIP E ++ T
Sbjct: 247 SLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELLTLIGAT 306
Query: 302 GISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTL 361
GIS G LK + VDVVG +P GL+PP P+T LF + A IA+VGF++ IS+ K
Sbjct: 307 GISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAISLGKIF 366
Query: 362 ANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMI 421
A +HGY+VD NQEL+ALGL N IG +FQ F +SCS+SRSLVQE TGG +Q+AG ++SL I
Sbjct: 367 ALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSLFI 426
Query: 422 LLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLF 481
LL+I+ G LF LP+AVL+AI+IVNLKGM Q SD+ W+ ++ +L IWL TF +++
Sbjct: 427 LLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTATIL 486
Query: 482 LGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQIN 541
L LD GL+ AVI +LL V+ RTQ P Y VLG++P+TD+Y D+ Y E KE+ G+K+F+ +
Sbjct: 487 LNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGVKVFRSS 546
Query: 542 APIYYANSDLYSNALKRKTGVNPAVIMGARRKAMR--------------KYAKEVGNANM 587
A +Y+AN++ YS+ALK++ GV+ ++ ++K ++ K K+ G
Sbjct: 547 ATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQAGPLLS 606
Query: 588 ANATVVKADAEVDGEDATKPEEEDGEVKYPPIVIKSTFPEEMQRFMPPGDNVHTVILDFT 647
A + + EDAT +ED K+ ++ P + H++ILD
Sbjct: 607 ACLAPQQVSSGDKMEDATANGQEDS---------KAPDGSTLKALGLPQPDFHSLILDLG 657
Query: 648 QVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFFENPALWELLFHSIH 707
++F+D+V +K+L I ++ ++ + VY+A C + VV+ L FF+ + LF S+H
Sbjct: 658 ALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGHFFDASITKKHLFASVH 717
Query: 708 DAV 710
DAV
Sbjct: 718 DAV 720
>gi|94721253 solute carrier family 26, member 6 isoform 1 [Homo
sapiens]
Length = 759
Score = 560 bits (1442), Expect = e-159
Identities = 300/742 (40%), Positives = 456/742 (61%), Gaps = 57/742 (7%)
Query: 9 ILAATQR-------YYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNII 61
+L+ATQ Y++ERP+ + L+E L P + + + C+ + ++
Sbjct: 15 LLSATQAMDLRRRDYHMERPLLNQEHLEE-LGRWGSAPRT--HQWRTWLQCSRARAYALL 71
Query: 62 YMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVI 121
LP+ WLP Y ++++LGDL+SG+S ++QLPQGLA+A+LA +PP+FGLYSSFYPV
Sbjct: 72 LQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFYPVF 131
Query: 122 MYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMS 181
+Y GTSRHIS+G FAV+S+M+G V L P + +N T ARDA RV+VA +
Sbjct: 132 IYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQALN-DSMINET----ARDAARVQVAST 186
Query: 182 VTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIF 241
+++L G+ Q LG+ FGFV YL+EPLVRG+TTAAAV VF S LKY+FG+ +SG
Sbjct: 187 LSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPL 246
Query: 242 SVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGT 301
S++Y+ + V + V ++ + +L+ K N++ +++LP PIP E ++ T
Sbjct: 247 SLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELLTLIGAT 306
Query: 302 GISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTL 361
GIS G LK + VDVVG +P GL+PP P+T LF + A IA+VGF++ IS+ K
Sbjct: 307 GISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAISLGKIF 366
Query: 362 ANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMI 421
A +HGY+VD NQEL+ALGL N IG +FQ F +SCS+SRSLVQE TGG +Q+AG ++SL I
Sbjct: 367 ALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSLFI 426
Query: 422 LLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLF 481
LL+I+ G LF LP+AVL+AI+IVNLKGM Q SD+ W+ ++ +L IWL TF +++
Sbjct: 427 LLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTATIL 486
Query: 482 LGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQIN 541
L LD GL+ AVI +LL V+ RTQ P Y VLG++P+TD+Y D+ Y E KE+ G+K+F+ +
Sbjct: 487 LNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGVKVFRSS 546
Query: 542 APIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKY----------------------- 578
A +Y+AN++ YS+ALK++ GV+ ++ ++K ++K
Sbjct: 547 ATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQAASPKG 606
Query: 579 ----------AKEVGNANMANATVVKADAEVDGEDATKPEEEDGEVKYPPIVIKSTFPEE 628
+++ + N+ + +++ + EDAT +ED K+
Sbjct: 607 ASVSINVNTSLEDMRSNNVEDCKMMQVSSGDKMEDATANGQEDS---------KAPDGST 657
Query: 629 MQRFMPPGDNVHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLT 688
++ P + H++ILD ++F+D+V +K+L I ++ ++ + VY+A C + VV+ L
Sbjct: 658 LKALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLE 717
Query: 689 RNRFFENPALWELLFHSIHDAV 710
FF+ + LF S+HDAV
Sbjct: 718 AGHFFDASITKKHLFASVHDAV 739
>gi|94721259 solute carrier family 26, member 6 isoform 4 [Homo
sapiens]
Length = 738
Score = 559 bits (1440), Expect = e-159
Identities = 296/728 (40%), Positives = 450/728 (61%), Gaps = 50/728 (6%)
Query: 16 YYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAYK 75
Y++ERP+ + L+E L P + + + C+ + ++ LP+ WLP Y
Sbjct: 8 YHMERPLLNQEHLEE-LGRWGSAPRT--HQWRTWLQCSRARAYALLLQHLPVLVWLPRYP 64
Query: 76 FKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIG 135
++++LGDL+SG+S ++QLPQGLA+A+LA +PP+FGLYSSFYPV +Y GTSRHIS+G
Sbjct: 65 VRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFYPVFIYFLFGTSRHISVG 124
Query: 136 PFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGV 195
FAV+S+M+G V L P + +N T ARDA RV+VA ++++L G+ Q LG+
Sbjct: 125 TFAVMSVMVGSVTESLAPQALN-DSMINET----ARDAARVQVASTLSVLVGLFQVGLGL 179
Query: 196 CRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVK 255
FGFV YL+EPLVRG+TTAAAV VF S LKY+FG+ +SG S++Y+ + V +
Sbjct: 180 IHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLP 239
Query: 256 NLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGTGISAGFNLKESYNV 315
V ++ + +L+ K N++ +++LP PIP E ++ TGIS G LK + V
Sbjct: 240 QSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELLTLIGATGISYGMGLKHRFEV 299
Query: 316 DVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQEL 375
DVVG +P GL+PP P+T LF + A IA+VGF++ IS+ K A +HGY+VD NQEL
Sbjct: 300 DVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQEL 359
Query: 376 IALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESL 435
+ALGL N IG +FQ F +SCS+SRSLVQE TGG +Q+AG ++SL ILL+I+ G LF L
Sbjct: 360 VALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDL 419
Query: 436 PQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIA 495
P+AVL+AI+IVNLKGM Q SD+ W+ ++ +L IWL TF +++ L LD GL+ AVI +
Sbjct: 420 PKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFS 479
Query: 496 LLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSNA 555
LL V+ RTQ P Y VLG++P+TD+Y D+ Y E KE+ G+K+F+ +A +Y+AN++ YS+A
Sbjct: 480 LLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGVKVFRSSATVYFANAEFYSDA 539
Query: 556 LKRKTGVNPAVIMGARRKAMRKY---------------------------------AKEV 582
LK++ GV+ ++ ++K ++K +++
Sbjct: 540 LKQRCGVDVDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQAASPKGASVSINVNTSLEDM 599
Query: 583 GNANMANATVVKADAEVDGEDATKPEEEDGEVKYPPIVIKSTFPEEMQRFMPPGDNVHTV 642
+ N+ + +++ + EDAT +ED K+ ++ P + H++
Sbjct: 600 RSNNVEDCKMMQVSSGDKMEDATANGQEDS---------KAPDGSTLKALGLPQPDFHSL 650
Query: 643 ILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFFENPALWELL 702
ILD ++F+D+V +K+L I ++ ++ + VY+A C + VV+ L FF+ + L
Sbjct: 651 ILDLGALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGHFFDASITKKHL 710
Query: 703 FHSIHDAV 710
F S+HDAV
Sbjct: 711 FASVHDAV 718
>gi|94721255 solute carrier family 26, member 6 isoform 2 [Homo
sapiens]
Length = 758
Score = 558 bits (1437), Expect = e-159
Identities = 303/741 (40%), Positives = 451/741 (60%), Gaps = 56/741 (7%)
Query: 9 ILAATQR-------YYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNII 61
+L+ATQ Y++ERP+ + L+E L P + + + C+ + ++
Sbjct: 15 LLSATQAMDLRRRDYHMERPLLNQEHLEE-LGRWGSAPRT--HQWRTWLQCSRARAYALL 71
Query: 62 YMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVI 121
LP+ WLP Y ++++LGDL+SG+S ++QLPQGLA+A+LA +PP+FGLYSSFYPV
Sbjct: 72 LQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFYPVF 131
Query: 122 MYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMS 181
+Y GTSRHIS+G FAV+S+M+G V L P + +N T ARDA RV+VA +
Sbjct: 132 IYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQALN-DSMINET----ARDAARVQVAST 186
Query: 182 VTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIF 241
+++L G+ Q LG+ FGFV YL+EPLVRG+TTAAAV VF S LKY+FG+ +SG
Sbjct: 187 LSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPL 246
Query: 242 SVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGT 301
S++Y+ + V + V ++ + +L+ K N++ +++LP PIP E ++ T
Sbjct: 247 SLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELLTLIGAT 306
Query: 302 GISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTL 361
GIS G LK + VDVVG +P GL+PP P+T LF + A IA+VGF++ IS+ K
Sbjct: 307 GISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAISLGKIF 366
Query: 362 ANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMI 421
A +HGY+VD NQEL+ALGL N IG +FQ F +SCS+SRSLVQE TGG +Q+AG ++SL I
Sbjct: 367 ALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSLFI 426
Query: 422 LLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLF 481
LL+I+ G LF LP+AVL+AI+IVNLKGM Q SD+ W+ ++ +L IWL TF +++
Sbjct: 427 LLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTATIL 486
Query: 482 LGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQIN 541
L LD GL+ AVI +LL V+ RTQ P Y VLG++P+TD+Y D+ Y E KE+ G+K+F+ +
Sbjct: 487 LNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGVKVFRSS 546
Query: 542 APIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKY------------------AKEVG 583
A +Y+AN++ YS+ALK++ GV+ ++ ++K ++K A G
Sbjct: 547 ATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQAASPKG 606
Query: 584 NANMANATVVKADAEVDG--------------EDATKPEEEDGEVKYPPIVIKSTFPEEM 629
+ N D + EDAT +ED K+ +
Sbjct: 607 ASVSINVNTSLEDMRSNNVEDCKMMVSSGDKMEDATANGQEDS---------KAPDGSTL 657
Query: 630 QRFMPPGDNVHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTR 689
+ P + H++ILD ++F+D+V +K+L I ++ ++ + VY+A C + VV+ L
Sbjct: 658 KALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEA 717
Query: 690 NRFFENPALWELLFHSIHDAV 710
FF+ + LF S+HDAV
Sbjct: 718 GHFFDASITKKHLFASVHDAV 738
>gi|4505697 pendrin [Homo sapiens]
Length = 780
Score = 538 bits (1385), Expect = e-153
Identities = 277/723 (38%), Positives = 437/723 (60%), Gaps = 14/723 (1%)
Query: 16 YYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAYK 75
Y V RP++S Q++ + + ++ + L + +C+ K+ ++ +PI +WLP Y+
Sbjct: 20 YMVSRPVYSELAFQQQHERRLQERKTLRESLAKCCSCSRKRAFGVLKTLVPILEWLPKYR 79
Query: 76 FKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIG 135
KE++L D++SG+STG++ QG+A+A+LAAVP +GLYS+F+P++ Y GTSRHIS+G
Sbjct: 80 VKEWLLSDVISGVSTGLVATLQGMAYALLAAVPVGYGLYSAFFPILTYFIFGTSRHISVG 139
Query: 136 PFAVISLMIGGVAVRLVPDDIVIPGGVNATN------GTEARDALRVKVAMSVTLLSGII 189
PF V+SLM+G V + + PD+ + N T T ARD RV +A ++TLL GII
Sbjct: 140 PFPVVSLMVGSVVLSMAPDEHFLVSSSNGTVLNTTMIDTAARDTARVLIASALTLLVGII 199
Query: 190 QFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVA 249
Q G + GF+ YL +PLV GFTTAAA V S LK + V TK Y+G+ S++Y+ V
Sbjct: 200 QLIFGGLQIGFIVRYLADPLVGGFTTAAAFQVLVSQLKIVLNVSTKNYNGVLSIIYTLVE 259
Query: 250 VLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGTGISAGFNL 309
+ QN+ + N+ GL+ + + KE N+RF+ K+P PIP+E ++ T IS G NL
Sbjct: 260 IFQNIGDTNLADFTAGLLTIVVCMAVKELNDRFRHKIPVPIPIEVIVTIIATAISYGANL 319
Query: 310 KESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQV 369
+++YN +V ++P G LPP P SLF + + +IA+V +++ +S+ K A K+ Y +
Sbjct: 320 EKNYNAGIVKSIPRGFLPPELPPVSLFSEMLAASFSIAVVAYAIAVSVGKVYATKYDYTI 379
Query: 370 DGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATG 429
DGNQE IA G+ N F F + +LSR+ VQE TGGKTQ+AG +++ ++++ ILA G
Sbjct: 380 DGNQEFIAFGISNIFSGFFSCFVATTALSRTAVQESTGGKTQVAGIISAAIVMIAILALG 439
Query: 430 FLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLI 489
L E L ++VL+A+VI NLKGMFMQ D+P WR +KI+ IW+ T + S+ LGLD GL+
Sbjct: 440 KLLEPLQKSVLAAVVIANLKGMFMQLCDIPRLWRQNKIDAVIWVFTCIVSIILGLDLGLL 499
Query: 490 TAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQINAPIYYANS 549
+I LLTV+ R Q PS+ LG +P TD+Y Y+ ++E G+KI + ++PI+Y N
Sbjct: 500 AGLIFGLLTVVLRVQFPSWNGLGSIPSTDIYKSTKNYKNIEEPQGVKILRFSSPIFYGNV 559
Query: 550 DLYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANM-ANATVVKADAEVDGEDATKPE 608
D + +K G + + R KA+RK K + + + A + +DA V +A +P+
Sbjct: 560 DGFKKCIKSTVGFDAIRVYNKRLKALRKIQKLIKSGQLRATKNGIISDA-VSTNNAFEPD 618
Query: 609 E-----EDGEVKYPPIVIKSTFPEEMQ-RFMPPGDNVHTVILDFTQVNFIDSVGVKTLAG 662
E E+ ++ I I+ + E+ + P +H+++LD ++F+D VGV++L
Sbjct: 619 EDIEDLEELDIPTKEIEIQVDWNSELPVKVNVPKVPIHSLVLDCGAISFLDVVGVRSLRV 678
Query: 663 IVKEYGDVGIYVYLAGCSAQVVNDLTRNRFFENPALWELLFHSIHDAVLGSQLREALAEQ 722
IVKE+ + + VY A V+ L + FF++ + F ++HDA+L Q + E
Sbjct: 679 IVKEFQRIDVNVYFASLQDYVIEKLEQCGFFDDNIRKDTFFLTVHDAILYLQNQVKSQEG 738
Query: 723 EAS 725
+ S
Sbjct: 739 QGS 741
>gi|4557535 solute carrier family 26, member 3 [Homo sapiens]
Length = 764
Score = 513 bits (1322), Expect = e-145
Identities = 288/735 (39%), Positives = 432/735 (58%), Gaps = 24/735 (3%)
Query: 15 RYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAY 74
+Y V RP++S +E + + D LK +C+P+K + I+ PI WLPAY
Sbjct: 8 QYIVARPVYSTNAFEENHKKTGRHHKTFLDHLKVCCSCSPQKAKRIVLSLFPIASWLPAY 67
Query: 75 KFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISI 134
+ KE++L D+VSGISTG++ + QGLAFA+L +PP++GLY+SF+P I+Y F GTSRHIS+
Sbjct: 68 RLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISV 127
Query: 135 GPFAVISLMIG----GVAVRLVPDDIVIPGGV-NATNGTEARDALRVKVAM--SVTLLSG 187
GPF ++S+M+G G + VPD G+ N +N + D RV+VA SVT+LSG
Sbjct: 128 GPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSG 187
Query: 188 IIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYS---GIFSVV 244
IIQ G+ R GFV IYL+E L+ GFTTAAAVHV S LK++F + ++ IF V+
Sbjct: 188 IIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVL 247
Query: 245 YSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGTGIS 304
YS V ++ N+ L L+V ++ KE N+RFK+KLP PIP+EF V+ G+S
Sbjct: 248 YS---VFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVS 304
Query: 305 AGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANK 364
G + K + V VVG + G PP PD F D IA+V F+V S+A + K
Sbjct: 305 YGCDFKNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLK 364
Query: 365 HGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLV 424
+ Y +DGNQELIALGL N + +F+ F+ S +LSRS VQE TGGKTQ+AG + ++++L+V
Sbjct: 365 YDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIV 424
Query: 425 ILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGL 484
+LA GFL L ++VL+A+ + NLKGM MQF+++ WR K + IW+ TF+ ++ LGL
Sbjct: 425 VLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGL 484
Query: 485 DYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQINAPI 544
GL +V LLT+++RTQ P L + T++Y + Y ++ E G+KIF+ +PI
Sbjct: 485 GLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPI 544
Query: 545 YYANSDLYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMANATVVKADAEVDGEDA 604
Y+AN + L G +P I+ R KA+RK K + + T VD
Sbjct: 545 YFANIGFFRRKLIDAVGFSPLRILRKRNKALRKIRK-LQKQGLLQVTPKGFICTVDTIKD 603
Query: 605 TKPEEEDGEVKYPPIVIKST---FPEEMQRFMP-----PGDNVHTVILDFTQVNFIDSVG 656
+ E ++ +++ I +T F + +P P ++H++ILDF+ V+F+D
Sbjct: 604 SDEELDNNQIEVLDQPINTTDLPFHIDWNDDLPLNIEVPKISLHSLILDFSAVSFLDVSS 663
Query: 657 VKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFFENPALWELLFHSIHDAVLGSQLR 716
V+ L I++E+ + + VY+ G + L R FF+ + F +IHDAVL ++
Sbjct: 664 VRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFFLTIHDAVLHILMK 723
Query: 717 EALAEQEASAPPSQE 731
+ + + + PSQE
Sbjct: 724 KDYSTSKFN--PSQE 736
>gi|16418413 solute carrier family 26, member 9 isoform a [Homo
sapiens]
Length = 791
Score = 492 bits (1266), Expect = e-139
Identities = 273/764 (35%), Positives = 437/764 (57%), Gaps = 47/764 (6%)
Query: 15 RYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAY 74
RY V+R +S + + KD+ + +KL+ AF C+ KI+ +++ LP+ WLP Y
Sbjct: 7 RYVVDRAAYSLTLFDDEFEKKDRTYP-VGEKLRNAFRCSSAKIKAVVFGLLPVLSWLPKY 65
Query: 75 KFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISI 134
K K+Y++ DL+ G+S G +Q+PQG+AFA+LA +P + GLYSSF+P++ Y FLG +
Sbjct: 66 KIKDYIIPDLLGGLSGGSIQVPQGMAFALLANLPAVNGLYSSFFPLLTYFFLGGVHQMVP 125
Query: 135 GPFAVISLMIGGVAVRLVPDDIVIPGGVNATN----GTEARDALRVKVAMSVTLLSGIIQ 190
G FAVIS+++G + ++L P+ NATN T A +A R+ V+ ++ L+ IIQ
Sbjct: 126 GTFAVISILVGNICLQLAPESKFQVFN-NATNESYVDTAAMEAERLHVSATLACLTAIIQ 184
Query: 191 FCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAV 250
LG +FGFVAIYL+E +RGF TAA + + S+LKY+FG+ Y+G S+V++ + +
Sbjct: 185 MGLGFMQFGFVAIYLSESFIRGFMTAAGLQILISVLKYIFGLTIPSYTGPGSIVFTFIDI 244
Query: 251 LQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGTGISAGFNLK 310
+N+ + N+ SL L+ L+ KE N R+ K+ PIP E VV+ T IS G +
Sbjct: 245 CKNLPHTNIASLIFALISGAFLVLVKELNARYMHKIRFPIPTEMIVVVVATAISGGCKMP 304
Query: 311 ESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQVD 370
+ Y++ +VG + G P +P S + + A ++AIV + + ++M +TLANKHGY VD
Sbjct: 305 KKYHMQIVGEIQRGFPTPVSPVVSQWKDMIGTAFSLAIVSYVINLAMGRTLANKHGYDVD 364
Query: 371 GNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGF 430
NQE+IALG N GS F+ I C+LS +L +G GGK+Q+A SL++++ +L G
Sbjct: 365 SNQEMIALGCSNFFGSFFKIHVICCALSVTLAVDGAGGKSQVASLCVSLVVMITMLVLGI 424
Query: 431 LFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLIT 490
LP++VL A++ VNLK Q +D + WR SK++ IW+ +F+SS FL L YG+
Sbjct: 425 YLYPLPKSVLGALIAVNLKNSLKQLTDPYYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAV 484
Query: 491 AVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQINAPIYYANSD 550
V ++L V+++TQ + L ++ +TD+Y++ Y ++I GIKI +P+Y+ANS+
Sbjct: 485 GVAFSVLVVVFQTQFRNGYALAQVMDTDIYVNPKTYNRAQDIQGIKIITYCSPLYFANSE 544
Query: 551 LYSNALKRKTGVNPAVIMGARRKAMRKYAK-------EVGNANMANATVVKADAEVDGED 603
++ + KTG++P ++ A++K ++K K + + M TV + + D E+
Sbjct: 545 IFRQKVIAKTGMDPQKVLLAKQKYLKKQEKRRMRPTQQRRSLFMKTKTVSLQELQQDFEN 604
Query: 604 AT---------------------KPEEEDGEVKYPPIVIKST-FPEEMQRFMPPGDNVHT 641
A P+ PP ++ P +M +PP HT
Sbjct: 605 APPTDPNNNQTPANGTSVSYITFSPDSSSPAQSEPPASAEAPGEPSDMLASVPPFVTFHT 664
Query: 642 VILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFFENPAL-WE 700
+ILD + V+F+D +G+K LA + YG +G+ V+L AQV ND++ FE+ +L +
Sbjct: 665 LILDMSGVSFVDLMGIKALAKLSSTYGKIGVKVFLVNIHAQVYNDISHGGVFEDGSLECK 724
Query: 701 LLFHSIHDAVL-----------GSQLREALAEQEASAPPSQEDL 733
+F SIHDAVL G + A + E S S+ED+
Sbjct: 725 HVFPSIHDAVLFAQANARDVTPGHNFQGAPGDAELSLYDSEEDI 768
>gi|217272867 solute carrier family 26, member 9 isoform b [Homo
sapiens]
Length = 887
Score = 492 bits (1266), Expect = e-139
Identities = 273/764 (35%), Positives = 437/764 (57%), Gaps = 47/764 (6%)
Query: 15 RYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAY 74
RY V+R +S + + KD+ + +KL+ AF C+ KI+ +++ LP+ WLP Y
Sbjct: 7 RYVVDRAAYSLTLFDDEFEKKDRTYP-VGEKLRNAFRCSSAKIKAVVFGLLPVLSWLPKY 65
Query: 75 KFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISI 134
K K+Y++ DL+ G+S G +Q+PQG+AFA+LA +P + GLYSSF+P++ Y FLG +
Sbjct: 66 KIKDYIIPDLLGGLSGGSIQVPQGMAFALLANLPAVNGLYSSFFPLLTYFFLGGVHQMVP 125
Query: 135 GPFAVISLMIGGVAVRLVPDDIVIPGGVNATN----GTEARDALRVKVAMSVTLLSGIIQ 190
G FAVIS+++G + ++L P+ NATN T A +A R+ V+ ++ L+ IIQ
Sbjct: 126 GTFAVISILVGNICLQLAPESKFQVFN-NATNESYVDTAAMEAERLHVSATLACLTAIIQ 184
Query: 191 FCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAV 250
LG +FGFVAIYL+E +RGF TAA + + S+LKY+FG+ Y+G S+V++ + +
Sbjct: 185 MGLGFMQFGFVAIYLSESFIRGFMTAAGLQILISVLKYIFGLTIPSYTGPGSIVFTFIDI 244
Query: 251 LQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGTGISAGFNLK 310
+N+ + N+ SL L+ L+ KE N R+ K+ PIP E VV+ T IS G +
Sbjct: 245 CKNLPHTNIASLIFALISGAFLVLVKELNARYMHKIRFPIPTEMIVVVVATAISGGCKMP 304
Query: 311 ESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQVD 370
+ Y++ +VG + G P +P S + + A ++AIV + + ++M +TLANKHGY VD
Sbjct: 305 KKYHMQIVGEIQRGFPTPVSPVVSQWKDMIGTAFSLAIVSYVINLAMGRTLANKHGYDVD 364
Query: 371 GNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGF 430
NQE+IALG N GS F+ I C+LS +L +G GGK+Q+A SL++++ +L G
Sbjct: 365 SNQEMIALGCSNFFGSFFKIHVICCALSVTLAVDGAGGKSQVASLCVSLVVMITMLVLGI 424
Query: 431 LFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLIT 490
LP++VL A++ VNLK Q +D + WR SK++ IW+ +F+SS FL L YG+
Sbjct: 425 YLYPLPKSVLGALIAVNLKNSLKQLTDPYYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAV 484
Query: 491 AVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQINAPIYYANSD 550
V ++L V+++TQ + L ++ +TD+Y++ Y ++I GIKI +P+Y+ANS+
Sbjct: 485 GVAFSVLVVVFQTQFRNGYALAQVMDTDIYVNPKTYNRAQDIQGIKIITYCSPLYFANSE 544
Query: 551 LYSNALKRKTGVNPAVIMGARRKAMRKYAK-------EVGNANMANATVVKADAEVDGED 603
++ + KTG++P ++ A++K ++K K + + M TV + + D E+
Sbjct: 545 IFRQKVIAKTGMDPQKVLLAKQKYLKKQEKRRMRPTQQRRSLFMKTKTVSLQELQQDFEN 604
Query: 604 AT---------------------KPEEEDGEVKYPPIVIKST-FPEEMQRFMPPGDNVHT 641
A P+ PP ++ P +M +PP HT
Sbjct: 605 APPTDPNNNQTPANGTSVSYITFSPDSSSPAQSEPPASAEAPGEPSDMLASVPPFVTFHT 664
Query: 642 VILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFFENPAL-WE 700
+ILD + V+F+D +G+K LA + YG +G+ V+L AQV ND++ FE+ +L +
Sbjct: 665 LILDMSGVSFVDLMGIKALAKLSSTYGKIGVKVFLVNIHAQVYNDISHGGVFEDGSLECK 724
Query: 701 LLFHSIHDAVL-----------GSQLREALAEQEASAPPSQEDL 733
+F SIHDAVL G + A + E S S+ED+
Sbjct: 725 HVFPSIHDAVLFAQANARDVTPGHNFQGAPGDAELSLYDSEEDI 768
>gi|100913030 solute carrier family 26 member 2 [Homo sapiens]
Length = 739
Score = 461 bits (1187), Expect = e-130
Identities = 257/702 (36%), Positives = 401/702 (57%), Gaps = 53/702 (7%)
Query: 25 HPVLQERLHTKD-KVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGD 83
H +L ER D + + KL++ C+P K +N+I FLP+ +WLP Y K+ +LGD
Sbjct: 52 HRILIERQEKSDTNFKEFVIKKLQKNCQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGD 111
Query: 84 LVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLM 143
++SG+ G+L +PQ +A+++LA P++GLY+SF+ I+Y LGTSRHIS+G F V+ LM
Sbjct: 112 VMSGLIVGILLVPQSIAYSLLAGQEPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLM 171
Query: 144 IGGVAVRLV-----------PDDIVIPGGVNATNGTEAR----DALRVKVAMSVTLLSGI 188
IG R + P ++ G N T R + V +VT ++G+
Sbjct: 172 IGETVDRELQKAGYDNAHSAPSLGMVSNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGV 231
Query: 189 IQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTV 248
Q +G + GFV++YL++ L+ GF T A+ + TS KYL G+ R +G+ S++ + +
Sbjct: 232 YQVAMGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTWI 291
Query: 249 AVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGTGISAGFN 308
V +N+ N+C L L+ +LL KE NE FK KL APIP+E VV T S
Sbjct: 292 HVFRNIHKTNLCDLITSLLCLLVLLPTKELNEHFKSKLKAPIPIELVVVVAATLASHFGK 351
Query: 309 LKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQ 368
L E+YN + G +P G +PP P+ +L V VDAIAI+I+GF++T+S+++ A KHGY
Sbjct: 352 LHENYNSSIAGHIPTGFMPPKVPEWNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGYT 411
Query: 369 VDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILAT 428
V NQE+ A+G CN I S F F+ S +L+++LV+E TG TQL+G + +L++LLV+L
Sbjct: 412 VKANQEMYAIGFCNIIPSFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVLLVI 471
Query: 429 GFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGL 488
LF SL ++VL I IVNL+G +F DLP W S+++ IW T +SS L + GL
Sbjct: 472 APLFYSLQKSVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTEIGL 531
Query: 489 ITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQINAPIYYAN 548
+ V ++ VI RTQ P +LG + E++V+ + AY+ ++ PGIKIF+ AP+YY N
Sbjct: 532 LVGVCFSIFCVILRTQKPKSSLLGLVEESEVFESVSAYKNLQIKPGIKIFRFVAPLYYIN 591
Query: 549 SDLYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMANATVVKADAEVDGEDATKPE 608
+ + +AL ++T VNP +I A +KA ++ KE VV D
Sbjct: 592 KECFKSALYKQT-VNPILIKVAWKKAAKRKIKE---------KVVTLGGIQD-------- 633
Query: 609 EEDGEVKYPPIVIKSTFPEEMQRFMPPGDNVHTVILDFTQVNFIDSVGVKTLAGIVKEYG 668
E ++ + P+ +HT+++D + + F+D+ G+ TL + ++Y
Sbjct: 634 EMSVQLSHDPL------------------ELHTIVIDCSAIQFLDTAGIHTLKEVRRDYE 675
Query: 669 DVGIYVYLAGCSAQVVNDLTRNRFFENPALWELLFHSIHDAV 710
+GI V LA C+ V + LT + + LLF+S+++A+
Sbjct: 676 AIGIQVLLAQCNPTVRDSLTNGEYCKKEE-ENLLFYSVYEAM 716
>gi|47131207 solute carrier family 26, member 1 isoform a [Homo
sapiens]
Length = 701
Score = 414 bits (1064), Expect = e-115
Identities = 233/683 (34%), Positives = 389/683 (56%), Gaps = 49/683 (7%)
Query: 51 TCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPI 110
+C+ +R ++ LP T+WL Y+ +EY+ GD++SG+ G++ +PQ +A+++LA + PI
Sbjct: 40 SCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPI 99
Query: 111 FGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVP-------DDIVIPGGVN 163
+ LY+SF+ ++Y +GTSRH+S+G F+++ LM+G V R + D + PG +
Sbjct: 100 YSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANS 159
Query: 164 AT-NGTEA-----RDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAA 217
+T NG+ A RD ++VA ++TL++G+ Q +GV R GFV+ YL++PL+ GF A
Sbjct: 160 STLNGSAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGA 219
Query: 218 AVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKE 277
+V + TS LK+L GV+ R+ G VV + +++L+ NVC + + +LL KE
Sbjct: 220 SVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKE 279
Query: 278 FNERFKEKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFH 337
++R++ +L P+P E +V+ T +S L + + V G +P G +PP P+ L
Sbjct: 280 LSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPRLMQ 339
Query: 338 LVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSL 397
V +DA+A+A+V + +IS+A+ A HGY V NQEL+A+G CN + + F+ S +L
Sbjct: 340 RVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAAL 399
Query: 398 SRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSD 457
++SLV+ TG +TQL+ +++ ++LLV+LA LF L ++VL+ +++V+L+G + D
Sbjct: 400 AKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWD 459
Query: 458 LPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPET 517
LP WR S + +W T + + + + GL+ VI++LL++ RTQ P +L ++ +T
Sbjct: 460 LPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDT 519
Query: 518 DVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRK 577
Y D +E + PG+++F+ P+YYAN D + +L TG++ A M ARRK
Sbjct: 520 AFYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLD-AGCMAARRK---- 574
Query: 578 YAKEVGNANMANATVVKADAEVDGEDATKPEEEDGEVKYPPIVIKSTFPEEMQRFMPPGD 637
+ T V GED P+ ++ +P
Sbjct: 575 --------EGGSETGVGEGGPAQGEDLG------------PVSTRAAL-------VPAAA 607
Query: 638 NVHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFF-ENP 696
HTV++D + F+D+ GV TL + ++YG +GI + LA CS V + L+R F E P
Sbjct: 608 GFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLLACCSPPVRDILSRGGFLGEGP 667
Query: 697 ---ALWELLFHSIHDAVLGSQLR 716
A E LF S+HDAV ++ R
Sbjct: 668 GDTAEEEQLFLSVHDAVQTARAR 690
>gi|20336272 solute carrier family 26, member 1 isoform a [Homo
sapiens]
Length = 701
Score = 414 bits (1064), Expect = e-115
Identities = 233/683 (34%), Positives = 389/683 (56%), Gaps = 49/683 (7%)
Query: 51 TCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPI 110
+C+ +R ++ LP T+WL Y+ +EY+ GD++SG+ G++ +PQ +A+++LA + PI
Sbjct: 40 SCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPI 99
Query: 111 FGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVP-------DDIVIPGGVN 163
+ LY+SF+ ++Y +GTSRH+S+G F+++ LM+G V R + D + PG +
Sbjct: 100 YSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANS 159
Query: 164 AT-NGTEA-----RDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAA 217
+T NG+ A RD ++VA ++TL++G+ Q +GV R GFV+ YL++PL+ GF A
Sbjct: 160 STLNGSAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGA 219
Query: 218 AVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKE 277
+V + TS LK+L GV+ R+ G VV + +++L+ NVC + + +LL KE
Sbjct: 220 SVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKE 279
Query: 278 FNERFKEKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFH 337
++R++ +L P+P E +V+ T +S L + + V G +P G +PP P+ L
Sbjct: 280 LSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPRLMQ 339
Query: 338 LVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSL 397
V +DA+A+A+V + +IS+A+ A HGY V NQEL+A+G CN + + F+ S +L
Sbjct: 340 RVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAAL 399
Query: 398 SRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSD 457
++SLV+ TG +TQL+ +++ ++LLV+LA LF L ++VL+ +++V+L+G + D
Sbjct: 400 AKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWD 459
Query: 458 LPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPET 517
LP WR S + +W T + + + + GL+ VI++LL++ RTQ P +L ++ +T
Sbjct: 460 LPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDT 519
Query: 518 DVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRK 577
Y D +E + PG+++F+ P+YYAN D + +L TG++ A M ARRK
Sbjct: 520 AFYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLD-AGCMAARRK---- 574
Query: 578 YAKEVGNANMANATVVKADAEVDGEDATKPEEEDGEVKYPPIVIKSTFPEEMQRFMPPGD 637
+ T V GED P+ ++ +P
Sbjct: 575 --------EGGSETGVGEGGPAQGEDLG------------PVSTRAAL-------VPAAA 607
Query: 638 NVHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFF-ENP 696
HTV++D + F+D+ GV TL + ++YG +GI + LA CS V + L+R F E P
Sbjct: 608 GFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLLACCSPPVRDILSRGGFLGEGP 667
Query: 697 ---ALWELLFHSIHDAVLGSQLR 716
A E LF S+HDAV ++ R
Sbjct: 668 GDTAEEEQLFLSVHDAVQTARAR 690
>gi|16306483 solute carrier family 26, member 7 isoform a [Homo
sapiens]
Length = 656
Score = 300 bits (769), Expect = 2e-81
Identities = 163/487 (33%), Positives = 267/487 (54%), Gaps = 4/487 (0%)
Query: 65 LPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYC 124
LPI W P Y KE +L D VSGI V Q+ QGLAFA+L++V P+FGLY S +P I+Y
Sbjct: 32 LPILDWAPHYNLKENLLPDTVSGIMLAVQQVTQGLAFAVLSSVHPVFGLYGSLFPAIIYA 91
Query: 125 FLGTSRHISIGPFAVISLMIGGVAVRLVPDDI--VIPGGVNATNGTEARDALRVKVAMSV 182
G H++ G FA+ SL+ R+VP ++ + + G + R+ VA +V
Sbjct: 92 IFGMGHHVATGTFALTSLISANAVERIVPQNMQNLTTQSNTSVLGLSDFEMQRIHVAAAV 151
Query: 183 TLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFS 242
+ L G+IQ + V + G +TEP++ TT AA HV TS +KYL G+K SG
Sbjct: 152 SFLGGVIQVAMFVLQLGSATFVVTEPVISAMTTGAATHVVTSQVKYLLGMKMPYISGPLG 211
Query: 243 VVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGTG 302
Y V +N+K++ + +L + L+ +L+ KE NE+FK K+ +P++ ++ +
Sbjct: 212 FFYIYAYVFENIKSVRLEALLLSLLSIVVLVLVKELNEQFKRKIKVVLPVDLVLIIAASF 271
Query: 303 ISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLA 362
N++ +Y ++VVG +P G+ P P ++ V +A +A+VG+ ++++A+ A
Sbjct: 272 ACYCTNMENTYGLEVVGHIPQGIPSPRAPPMNILSAVITEAFGVALVGYVASLALAQGSA 331
Query: 363 NKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMIL 422
K Y +D NQE +A GL N + S F + ++ R+ TG KTQ+A ++ + +L
Sbjct: 332 KKFKYSIDDNQEFLAHGLSNIVSSFFFCIPSAAAMGRTAGLYSTGAKTQVACLISCIFVL 391
Query: 423 LVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFL 482
+VI A G L LP VL++I++V LKGM +QF DL +W KI+ IW++T+V ++
Sbjct: 392 IVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQFRDLKKYWNVDKIDWGIWVSTYVFTICF 451
Query: 483 GLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQINA 542
+ GL+ V+ + VI R + + E + + + E + +KI IN
Sbjct: 452 AANVGLLFGVVCTIAIVIGRFPRAMTVSIKNMKEMEFKVKTEMDSET--LQQVKIISINN 509
Query: 543 PIYYANS 549
P+ + N+
Sbjct: 510 PLVFLNA 516
>gi|20336282 solute carrier family 26, member 7 isoform b [Homo
sapiens]
Length = 663
Score = 300 bits (769), Expect = 2e-81
Identities = 163/487 (33%), Positives = 267/487 (54%), Gaps = 4/487 (0%)
Query: 65 LPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYC 124
LPI W P Y KE +L D VSGI V Q+ QGLAFA+L++V P+FGLY S +P I+Y
Sbjct: 32 LPILDWAPHYNLKENLLPDTVSGIMLAVQQVTQGLAFAVLSSVHPVFGLYGSLFPAIIYA 91
Query: 125 FLGTSRHISIGPFAVISLMIGGVAVRLVPDDI--VIPGGVNATNGTEARDALRVKVAMSV 182
G H++ G FA+ SL+ R+VP ++ + + G + R+ VA +V
Sbjct: 92 IFGMGHHVATGTFALTSLISANAVERIVPQNMQNLTTQSNTSVLGLSDFEMQRIHVAAAV 151
Query: 183 TLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFS 242
+ L G+IQ + V + G +TEP++ TT AA HV TS +KYL G+K SG
Sbjct: 152 SFLGGVIQVAMFVLQLGSATFVVTEPVISAMTTGAATHVVTSQVKYLLGMKMPYISGPLG 211
Query: 243 VVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGTG 302
Y V +N+K++ + +L + L+ +L+ KE NE+FK K+ +P++ ++ +
Sbjct: 212 FFYIYAYVFENIKSVRLEALLLSLLSIVVLVLVKELNEQFKRKIKVVLPVDLVLIIAASF 271
Query: 303 ISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLA 362
N++ +Y ++VVG +P G+ P P ++ V +A +A+VG+ ++++A+ A
Sbjct: 272 ACYCTNMENTYGLEVVGHIPQGIPSPRAPPMNILSAVITEAFGVALVGYVASLALAQGSA 331
Query: 363 NKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMIL 422
K Y +D NQE +A GL N + S F + ++ R+ TG KTQ+A ++ + +L
Sbjct: 332 KKFKYSIDDNQEFLAHGLSNIVSSFFFCIPSAAAMGRTAGLYSTGAKTQVACLISCIFVL 391
Query: 423 LVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFL 482
+VI A G L LP VL++I++V LKGM +QF DL +W KI+ IW++T+V ++
Sbjct: 392 IVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQFRDLKKYWNVDKIDWGIWVSTYVFTICF 451
Query: 483 GLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQINA 542
+ GL+ V+ + VI R + + E + + + E + +KI IN
Sbjct: 452 AANVGLLFGVVCTIAIVIGRFPRAMTVSIKNMKEMEFKVKTEMDSET--LQQVKIISINN 509
Query: 543 PIYYANS 549
P+ + N+
Sbjct: 510 PLVFLNA 516
>gi|16418457 solute carrier family 26, member 8 isoform a [Homo
sapiens]
Length = 970
Score = 282 bits (722), Expect = 7e-76
Identities = 158/505 (31%), Positives = 274/505 (54%), Gaps = 10/505 (1%)
Query: 52 CTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAA--VPP 109
C+ + + P +W+ Y+ K+++LGDL++GIS G++Q+PQGL ++LA +PP
Sbjct: 64 CSWHRFLRCVLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPP 123
Query: 110 IFGLYSSFYPVIMYCFLGTSRHISIGPFAVIS-LMIGGVAVRLVPDDIVIPGGVNATNGT 168
+ Y++F ++Y G+ +SIG F ++S L+I + V + ++ G N
Sbjct: 124 LNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLKVSPFNNGQLVMGSF-VKNEF 182
Query: 169 EARDALR-----VKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFT 223
A L + V + T L+GIIQ +GV GF+A YL E + + A A+H+
Sbjct: 183 SAPSYLMGYNKSLSVVATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHIML 242
Query: 224 SMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFK 283
S L ++FG+ ++G S Y + + N S+ V L V L K F
Sbjct: 243 SQLTFIFGIMISFHAGPISFFYDIINYCVALPKANSTSILVFLTVVVALRINKCIRISFN 302
Query: 284 EKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDA 343
+ P P+E F ++ T I+ ++ + ++ +P L P PD SL + + A
Sbjct: 303 Q-YPIEFPMELFLIIGFTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQA 361
Query: 344 IAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQ 403
++++V + I + K +A+ H Y V+ NQ+LIA+GLCN + S F++ + +++R+++Q
Sbjct: 362 FSLSLVSSFLLIFLGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQ 421
Query: 404 EGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWR 463
+ +GG+ Q A + + ++LL+++ G F +LP AVL+ I++ N+ S+LP WR
Sbjct: 422 DKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWR 481
Query: 464 TSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDI 523
+ + +W+ TF SS+FLGLD GLI +V+ A R+ +LG++P T++Y I
Sbjct: 482 QDQYDCALWMMTFSSSIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRSI 541
Query: 524 DAYEEVKEIPGIKIFQINAPIYYAN 548
+ Y E+ IPG+KIFQ + I + N
Sbjct: 542 NDYREIITIPGVKIFQCCSSITFVN 566
Score = 67.8 bits (164), Expect = 4e-11
Identities = 34/93 (36%), Positives = 53/93 (56%)
Query: 638 NVHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFFENPA 697
+VHT+ILDF+ V+++DS G+ L I + + I + +AGC + +V RN FF+
Sbjct: 720 SVHTIILDFSMVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFDAGI 779
Query: 698 LWELLFHSIHDAVLGSQLREALAEQEASAPPSQ 730
LF S+HDAVL + R+ + E S S+
Sbjct: 780 TKTQLFLSVHDAVLFALSRKVIGSSELSIDESE 812
>gi|65506789 solute carrier family 26, member 10 [Homo sapiens]
Length = 563
Score = 258 bits (659), Expect = 1e-68
Identities = 142/374 (37%), Positives = 221/374 (59%), Gaps = 3/374 (0%)
Query: 98 GLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIV 157
G+AFA+LA+VPP+FGLY+SF+PV++Y LGT RH+S G FA++SLM G RLVP+ +V
Sbjct: 41 GMAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLMTGSAVERLVPEPLV 100
Query: 158 IPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAA 217
G ++ E DA RV VA +V SG + + V + G ++ +L+EP+V+ T+ A
Sbjct: 101 --GNLSGIE-KEQLDAQRVGVAAAVAFGSGALMLGMFVLQLGVLSTFLSEPVVKALTSGA 157
Query: 218 AVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKE 277
A+HV S L L G+ R G FS+ + ++L + + L + + LL+ KE
Sbjct: 158 ALHVLLSQLPSLLGLSLPRQIGCFSLFKTLASLLTALPRSSPAELTISALSLALLVPVKE 217
Query: 278 FNERFKEKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFH 337
N RF+++LP PIP E V++ + + ++ Y V +VG LP G P P+ +
Sbjct: 218 LNVRFRDRLPTPIPGEVVLVLLASVLCFTSSVDTRYQVQIVGLLPGGFPQPLLPNLAELP 277
Query: 338 LVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSL 397
+ D++ IA+V F+V+ S+A A+K+ Y +D NQE +A G N I SLF F S +L
Sbjct: 278 RILADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASNLISSLFSCFPNSATL 337
Query: 398 SRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSD 457
+ + + GGKTQLAG + ++L V+L G F LP+AVL+ I I +++ +F Q +
Sbjct: 338 ATTNLLVDAGGKTQLAGLFSCTVVLSVLLWLGPFFYYLPKAVLACINISSMRQVFCQMQE 397
Query: 458 LPFFWRTSKIELTI 471
LP W S+++ +
Sbjct: 398 LPQLWHISRVDFLL 411
Score = 36.6 bits (83), Expect = 0.087
Identities = 29/85 (34%), Positives = 41/85 (48%), Gaps = 8/85 (9%)
Query: 639 VHTVILDFTQVNFIDSVGVKTLAGIVKEYG----DVGIYVYLAGCSAQVVNDLTRNRFFE 694
V V+LDF+ V F D+ G + + + + D I + LA C+A V LTR +
Sbjct: 464 VRVVVLDFSGVTFADAAGAREVVQVRERLASRCRDARIRLLLAQCNALVQGTLTRVGLLD 523
Query: 695 NPALWELLFHSIHDA---VLGSQLR 716
+ LF S+ DA LGS LR
Sbjct: 524 R-VTPDQLFVSVQDAAAYALGSLLR 547
>gi|217272870 solute carrier family 26, member 9 isoform c [Homo
sapiens]
Length = 459
Score = 256 bits (655), Expect = 4e-68
Identities = 147/432 (34%), Positives = 237/432 (54%), Gaps = 41/432 (9%)
Query: 343 AIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLV 402
A ++AIV + + ++M +TLANKHGY VD NQE+IALG N GS F+ I C+LS +L
Sbjct: 5 AFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLA 64
Query: 403 QEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFW 462
+G GGK+Q+A SL++++ +L G LP++VL A++ VNLK Q +D + W
Sbjct: 65 VDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDPYYLW 124
Query: 463 RTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYID 522
R SK++ IW+ +F+SS FL L YG+ V ++L V+++TQ + L ++ +TD+Y++
Sbjct: 125 RKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTDIYVN 184
Query: 523 IDAYEEVKEIPGIKIFQINAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKYAK-- 580
Y ++I GIKI +P+Y+ANS+++ + KTG++P ++ A++K ++K K
Sbjct: 185 PKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQEKRR 244
Query: 581 -----EVGNANMANATVVKADAEVDGEDAT---------------------KPEEEDGEV 614
+ + M TV + + D E+A P+
Sbjct: 245 MRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSSSPAQ 304
Query: 615 KYPPIVIKST-FPEEMQRFMPPGDNVHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIY 673
PP ++ P +M +PP HT+ILD + V+F+D +G+K LA + YG +G+
Sbjct: 305 SEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGKIGVK 364
Query: 674 VYLAGCSAQVVNDLTRNRFFENPAL-WELLFHSIHDAVL-----------GSQLREALAE 721
V+L AQV ND++ FE+ +L + +F SIHDAVL G + A +
Sbjct: 365 VFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSIHDAVLFAQANARDVTPGHNFQGAPGD 424
Query: 722 QEASAPPSQEDL 733
E S S+ED+
Sbjct: 425 AELSLYDSEEDI 436
>gi|85540447 solute carrier family 26, member 11 [Homo sapiens]
Length = 606
Score = 186 bits (473), Expect = 5e-47
Identities = 140/492 (28%), Positives = 235/492 (47%), Gaps = 68/492 (13%)
Query: 49 AFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVP 108
A C+P ++ LPI WLP+Y +++ D V+G+S G+ +PQ LA+A +A +P
Sbjct: 22 ACCCSPAALQRR----LPILAWLPSYSL-QWLKMDFVAGLSVGLTAIPQALAYAEVAGLP 76
Query: 109 PIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGT 168
P +GLYS+F +Y FLGTSR +++GP A++SL++
Sbjct: 77 PQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFH------------------ 118
Query: 169 EARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKY 228
A+ + LSG IQ +GV R GF+ +++ P+++GFT+AAAV + +K
Sbjct: 119 ------EPAYAVLLAFLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIGFGQIKN 172
Query: 229 LFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPA 288
L G++ F VY T + V +GL+ LLL K + P
Sbjct: 173 LLGLQNIP-RPFFLQVYHT---FLRIAETRVGDAVLGLVCMLLLLVLKLMRDHVPPVHPE 228
Query: 289 PIP-------LEFFAVVMGTGISAGFNLKESYNVDVVGTLPLGL-------LPP------ 328
P L + A + F +Y+ +V G P L LPP
Sbjct: 229 MPPGVRLSRGLVWAATTARNALVVSFAALVAYSFEVTGYQPFILTGETAEGLPPVRIPPF 288
Query: 329 ----ANPDTSLFHLVYVDAIAIAIV---GFSVTISMAKTLANKHGYQVDGNQELIALGLC 381
AN S +V +A+V G +I++AK A+++ Y++D NQEL+A+GL
Sbjct: 289 SVTTANGTISFTEMVQDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQELLAIGLT 348
Query: 382 NSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLS 441
N +GSL ++ ++ S R+ V +G T G + +++LL + LF +P++ L+
Sbjct: 349 NMLGSLVSSYPVTGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYIPKSALA 408
Query: 442 AIVIVNLKGMFMQFSDLPFF---WRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLT 498
A++I+ + +F D F WR +++L TF+ F + YG++ +++LL
Sbjct: 409 AVIIMAVAPLF----DTKIFRTLWRVKRLDLLPLCVTFL-LCFWEVQYGILAGALVSLLM 463
Query: 499 VIYRTQSPSYKV 510
+++ P KV
Sbjct: 464 LLHSAARPETKV 475
>gi|20336285 solute carrier family 26, member 8 isoform b [Homo
sapiens]
Length = 865
Score = 171 bits (432), Expect = 3e-42
Identities = 81/232 (34%), Positives = 141/232 (60%)
Query: 317 VVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELI 376
++ +P L P PD SL + + A ++++V + I + K +A+ H Y V+ NQ+LI
Sbjct: 230 LIDMIPYSFLLPVTPDFSLLPKIILQAFSLSLVSSFLLIFLGKKIASLHNYSVNSNQDLI 289
Query: 377 ALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLP 436
A+GLCN + S F++ + +++R+++Q+ +GG+ Q A + + ++LL+++ G F +LP
Sbjct: 290 AIGLCNVVSSFFRSCVFTGAIARTIIQDKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLP 349
Query: 437 QAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIAL 496
AVL+ I++ N+ S+LP WR + + +W+ TF SS+FLGLD GLI +V+ A
Sbjct: 350 NAVLAGIILSNVIPYLETISNLPSLWRQDQYDCALWMMTFSSSIFLGLDIGLIISVVSAF 409
Query: 497 LTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQINAPIYYAN 548
R+ +LG++P T++Y I+ Y E+ IPG+KIFQ + I + N
Sbjct: 410 FITTVRSHRAKILLLGQIPNTNIYRSINDYREIITIPGVKIFQCCSSITFVN 461
Score = 72.4 bits (176), Expect = 1e-12
Identities = 45/147 (30%), Positives = 79/147 (53%), Gaps = 9/147 (6%)
Query: 52 CTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLA--AVPP 109
C+ + + P +W+ Y+ K+++LGDL++GIS G++Q+PQGL ++LA +PP
Sbjct: 64 CSWHRFLRCMLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPP 123
Query: 110 IFGLYSSFYPVIMYCFLGTSRHISIGPFAVIS-LMIGGVAVRLVPDDIVIPGGVNATNGT 168
+ Y++F ++Y G+ +SIG F ++S L+I + V + ++ G N
Sbjct: 124 LNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLKVSPFNNGQLVMGSF-VKNEF 182
Query: 169 EARDAL-----RVKVAMSVTLLSGIIQ 190
A L + V + T L+GIIQ
Sbjct: 183 SAPSYLMGYNKSLSVVATTTFLTGIIQ 209
Score = 67.8 bits (164), Expect = 4e-11
Identities = 34/93 (36%), Positives = 53/93 (56%)
Query: 638 NVHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFFENPA 697
+VHT+ILDF+ V+++DS G+ L I + + I + +AGC + +V RN FF+
Sbjct: 615 SVHTIILDFSMVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFDAGI 674
Query: 698 LWELLFHSIHDAVLGSQLREALAEQEASAPPSQ 730
LF S+HDAVL + R+ + E S S+
Sbjct: 675 TKTQLFLSVHDAVLFALSRKVIGSSELSIDESE 707
>gi|20336274 solute carrier family 26, member 1 isoform b [Homo
sapiens]
Length = 224
Score = 109 bits (273), Expect = 8e-24
Identities = 56/157 (35%), Positives = 100/157 (63%), Gaps = 13/157 (8%)
Query: 51 TCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPI 110
+C+ +R ++ LP T+WL Y+ +EY+ GD++SG+ G++ +PQ +A+++LA + PI
Sbjct: 40 SCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPI 99
Query: 111 FGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLV-------PDDIVIPGGVN 163
+ LY+SF+ ++Y +GTSRH+S+G F+++ LM+G V R + D + PG +
Sbjct: 100 YSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANS 159
Query: 164 AT-NGTEA-----RDALRVKVAMSVTLLSGIIQFCLG 194
+T NG+ A RD ++VA ++TL++G+ Q G
Sbjct: 160 STLNGSAAMLDCGRDCYAIRVATALTLMTGLYQTSWG 196
>gi|32401433 G protein-coupled receptor 142 [Homo sapiens]
Length = 462
Score = 30.8 bits (68), Expect = 4.8
Identities = 19/44 (43%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
Query: 480 LFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDI 523
L LGL L+TAV +A L RT+ PSY L L +D+ I +
Sbjct: 167 LGLGLPVSLLTAVALARLAT--RTRRPSYYYLLALTASDIIIQV 208
>gi|18379366 zinc metallopeptidase STE24 [Homo sapiens]
Length = 475
Score = 30.0 bits (66), Expect = 8.1
Identities = 38/146 (26%), Positives = 64/146 (43%), Gaps = 16/146 (10%)
Query: 421 ILLVILATGF-LFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTS--KIELTIWLTTFV 477
++ ++LAT F LP ++ + VI G Q L FF + + K +T + V
Sbjct: 124 LVFLLLATLFSALTGLPWSLYNTFVIEEKHGFNQQ--TLGFFMKDAIKKFVVTQCILLPV 181
Query: 478 SSLFL-----GLDY-----GLITAVIIALLTVIYRTQ-SPSYKVLGKLPETDVYIDIDAY 526
SSL L G DY L T V+ +L IY +P + LPE + +I+
Sbjct: 182 SSLLLYIIKIGGDYFFIYAWLFTLVVSLVLVTIYADYIAPLFDKFTPLPEGKLKEEIEVM 241
Query: 527 EEVKEIPGIKIFQINAPIYYANSDLY 552
+ + P K++ + ++S+ Y
Sbjct: 242 AKSIDFPLTKVYVVEGSKRSSHSNAY 267
>gi|45827778 reticulon 1 isoform B [Homo sapiens]
Length = 356
Score = 30.0 bits (66), Expect = 8.1
Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 8/74 (10%)
Query: 466 KIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIY---RTQSPSYKVLGKLPETDVYID 522
K + +WL T+V +LF GL L+ V + L V+Y + Q Y L + V
Sbjct: 284 KFAVLMWLLTYVGALFNGLTLLLMAVVSMFTLPVVYVKHQAQIDQYLGLVRTHINAVVAK 343
Query: 523 IDAYEEVKEIPGIK 536
I A +IPG K
Sbjct: 344 IQA-----KIPGAK 352
>gi|45827776 reticulon 1 isoform C [Homo sapiens]
Length = 208
Score = 30.0 bits (66), Expect = 8.1
Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 8/74 (10%)
Query: 466 KIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIY---RTQSPSYKVLGKLPETDVYID 522
K + +WL T+V +LF GL L+ V + L V+Y + Q Y L + V
Sbjct: 136 KFAVLMWLLTYVGALFNGLTLLLMAVVSMFTLPVVYVKHQAQIDQYLGLVRTHINAVVAK 195
Query: 523 IDAYEEVKEIPGIK 536
I A +IPG K
Sbjct: 196 IQA-----KIPGAK 204
>gi|10863935 reticulon 1 isoform A [Homo sapiens]
Length = 776
Score = 30.0 bits (66), Expect = 8.1
Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 8/74 (10%)
Query: 466 KIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIY---RTQSPSYKVLGKLPETDVYID 522
K + +WL T+V +LF GL L+ V + L V+Y + Q Y L + V
Sbjct: 704 KFAVLMWLLTYVGALFNGLTLLLMAVVSMFTLPVVYVKHQAQIDQYLGLVRTHINAVVAK 763
Query: 523 IDAYEEVKEIPGIK 536
I A +IPG K
Sbjct: 764 IQA-----KIPGAK 772
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.139 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,366,401
Number of Sequences: 37866
Number of extensions: 1128533
Number of successful extensions: 2834
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2760
Number of HSP's gapped (non-prelim): 43
length of query: 744
length of database: 18,247,518
effective HSP length: 110
effective length of query: 634
effective length of database: 14,082,258
effective search space: 8928151572
effective search space used: 8928151572
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.