Guide to the Human Genome
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Search of human proteins with 38150007

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38150007 small nuclear ribonucleoprotein polypeptide B/B'
isoform B' [Homo sapiens]
         (240 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38150007 small nuclear ribonucleoprotein polypeptide B/B' iso...   508   e-144
gi|4507125 small nuclear ribonucleoprotein polypeptide B/B' isof...   481   e-136
gi|13027650 small nuclear ribonucleoprotein polypeptide N [Homo ...   481   e-136
gi|13027648 small nuclear ribonucleoprotein polypeptide N [Homo ...   481   e-136
gi|13027646 small nuclear ribonucleoprotein polypeptide N [Homo ...   481   e-136
gi|13027644 small nuclear ribonucleoprotein polypeptide N [Homo ...   481   e-136
gi|4507135 small nuclear ribonucleoprotein polypeptide N [Homo s...   481   e-136
gi|169216044 PREDICTED: similar to hCG2041320 [Homo sapiens]          234   5e-62
gi|169215838 PREDICTED: similar to hCG2041320 [Homo sapiens]          234   5e-62
gi|169215637 PREDICTED: similar to hCG2041320 [Homo sapiens]          234   5e-62
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                80   2e-15
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 75   4e-14
gi|160707881 formin 2 [Homo sapiens]                                   73   3e-13
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]                73   3e-13
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]               72   3e-13
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     70   1e-12
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    70   1e-12
gi|154800441 proline-rich protein HaeIII subfamily 1 [Homo sapiens]    70   1e-12
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     70   1e-12
gi|158966674 proline-rich protein HaeIII subfamily 2 [Homo sapiens]    70   2e-12
gi|4826944 proline-rich protein HaeIII subfamily 2 [Homo sapiens]      70   2e-12
gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]                 70   2e-12
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]                 70   2e-12
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]                 70   2e-12
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    69   3e-12
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    69   3e-12
gi|157168329 formin 1 [Homo sapiens]                                   69   4e-12
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    69   4e-12
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    69   4e-12
gi|4507127 small nuclear ribonucleoprotein polypeptide C [Homo s...    69   4e-12

>gi|38150007 small nuclear ribonucleoprotein polypeptide B/B'
           isoform B' [Homo sapiens]
          Length = 240

 Score =  508 bits (1307), Expect = e-144
 Identities = 240/240 (100%), Positives = 240/240 (100%)

Query: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAE 60
           MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAE
Sbjct: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAE 60

Query: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPM 120
           REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPM
Sbjct: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPM 120

Query: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG 180
           PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG
Sbjct: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG 180

Query: 181 RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPPGMRPPRP 240
           RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPPGMRPPRP
Sbjct: 181 RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPPGMRPPRP 240


>gi|4507125 small nuclear ribonucleoprotein polypeptide B/B' isoform
           B [Homo sapiens]
          Length = 231

 Score =  481 bits (1237), Expect = e-136
 Identities = 229/229 (100%), Positives = 229/229 (100%)

Query: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAE 60
           MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAE
Sbjct: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAE 60

Query: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPM 120
           REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPM
Sbjct: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPM 120

Query: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG 180
           PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG
Sbjct: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG 180

Query: 181 RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
           RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRG
Sbjct: 181 RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRG 229


>gi|13027650 small nuclear ribonucleoprotein polypeptide N [Homo
           sapiens]
          Length = 240

 Score =  481 bits (1237), Expect = e-136
 Identities = 223/240 (92%), Positives = 233/240 (97%)

Query: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAE 60
           MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKN+KQ E
Sbjct: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE 60

Query: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPM 120
           REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPG+GRAAGRG+PAGVP+
Sbjct: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI 120

Query: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG 180
           PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAA AATASIAGAPTQYPPGRG PPPP+G
Sbjct: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG 180

Query: 181 RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPPGMRPPRP 240
           R  PPPG+M PPPGMRPPMGPP+G+PP RGTP+GMPPPGMRPPPPG+RGPPPPGMRPPRP
Sbjct: 181 RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240


>gi|13027648 small nuclear ribonucleoprotein polypeptide N [Homo
           sapiens]
          Length = 240

 Score =  481 bits (1237), Expect = e-136
 Identities = 223/240 (92%), Positives = 233/240 (97%)

Query: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAE 60
           MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKN+KQ E
Sbjct: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE 60

Query: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPM 120
           REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPG+GRAAGRG+PAGVP+
Sbjct: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI 120

Query: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG 180
           PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAA AATASIAGAPTQYPPGRG PPPP+G
Sbjct: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG 180

Query: 181 RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPPGMRPPRP 240
           R  PPPG+M PPPGMRPPMGPP+G+PP RGTP+GMPPPGMRPPPPG+RGPPPPGMRPPRP
Sbjct: 181 RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240


>gi|13027646 small nuclear ribonucleoprotein polypeptide N [Homo
           sapiens]
          Length = 240

 Score =  481 bits (1237), Expect = e-136
 Identities = 223/240 (92%), Positives = 233/240 (97%)

Query: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAE 60
           MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKN+KQ E
Sbjct: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE 60

Query: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPM 120
           REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPG+GRAAGRG+PAGVP+
Sbjct: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI 120

Query: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG 180
           PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAA AATASIAGAPTQYPPGRG PPPP+G
Sbjct: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG 180

Query: 181 RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPPGMRPPRP 240
           R  PPPG+M PPPGMRPPMGPP+G+PP RGTP+GMPPPGMRPPPPG+RGPPPPGMRPPRP
Sbjct: 181 RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240


>gi|13027644 small nuclear ribonucleoprotein polypeptide N [Homo
           sapiens]
          Length = 240

 Score =  481 bits (1237), Expect = e-136
 Identities = 223/240 (92%), Positives = 233/240 (97%)

Query: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAE 60
           MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKN+KQ E
Sbjct: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE 60

Query: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPM 120
           REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPG+GRAAGRG+PAGVP+
Sbjct: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI 120

Query: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG 180
           PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAA AATASIAGAPTQYPPGRG PPPP+G
Sbjct: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG 180

Query: 181 RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPPGMRPPRP 240
           R  PPPG+M PPPGMRPPMGPP+G+PP RGTP+GMPPPGMRPPPPG+RGPPPPGMRPPRP
Sbjct: 181 RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240


>gi|4507135 small nuclear ribonucleoprotein polypeptide N [Homo
           sapiens]
          Length = 240

 Score =  481 bits (1237), Expect = e-136
 Identities = 223/240 (92%), Positives = 233/240 (97%)

Query: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAE 60
           MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKN+KQ E
Sbjct: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE 60

Query: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPM 120
           REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPG+GRAAGRG+PAGVP+
Sbjct: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI 120

Query: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG 180
           PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAA AATASIAGAPTQYPPGRG PPPP+G
Sbjct: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG 180

Query: 181 RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPPGMRPPRP 240
           R  PPPG+M PPPGMRPPMGPP+G+PP RGTP+GMPPPGMRPPPPG+RGPPPPGMRPPRP
Sbjct: 181 RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240


>gi|169216044 PREDICTED: similar to hCG2041320 [Homo sapiens]
          Length = 318

 Score =  234 bits (597), Expect = 5e-62
 Identities = 114/141 (80%), Positives = 123/141 (87%)

Query: 7   SKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRV 66
           +++ QHIDYRM+CILQ+G IF G FKAFDKH+NLILCDCDEFRKIKPKN KQ E EEK  
Sbjct: 152 ARLQQHIDYRMKCILQEGTIFFGIFKAFDKHVNLILCDCDEFRKIKPKNVKQPELEEKHF 211

Query: 67  LGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAG 126
            GLVLL GENLVSMTVEG PPK TGIARVPLAGAAGGPG+ RAAGRG+ AGVP+PQAP G
Sbjct: 212 WGLVLLHGENLVSMTVEGLPPKYTGIARVPLAGAAGGPGVVRAAGRGVSAGVPIPQAPGG 271

Query: 127 LAGPVRGVGGPSQQVMTPQGR 147
           LAGPV GVGGPSQQVMTPQ R
Sbjct: 272 LAGPVPGVGGPSQQVMTPQRR 292



 Score = 30.4 bits (67), Expect = 1.4
 Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 4/44 (9%)

Query: 200 GPPMGIPPGRGTPMGMP----PPGMRPPPPGMRGPPPPGMRPPR 239
           GP +    GRG   G+P    P G+  P PG+ GP    M P R
Sbjct: 248 GPGVVRAAGRGVSAGVPIPQAPGGLAGPVPGVGGPSQQVMTPQR 291


>gi|169215838 PREDICTED: similar to hCG2041320 [Homo sapiens]
          Length = 318

 Score =  234 bits (597), Expect = 5e-62
 Identities = 114/141 (80%), Positives = 123/141 (87%)

Query: 7   SKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRV 66
           +++ QHIDYRM+CILQ+G IF G FKAFDKH+NLILCDCDEFRKIKPKN KQ E EEK  
Sbjct: 152 ARLQQHIDYRMKCILQEGTIFFGIFKAFDKHVNLILCDCDEFRKIKPKNVKQPELEEKHF 211

Query: 67  LGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAG 126
            GLVLL GENLVSMTVEG PPK TGIARVPLAGAAGGPG+ RAAGRG+ AGVP+PQAP G
Sbjct: 212 WGLVLLHGENLVSMTVEGLPPKYTGIARVPLAGAAGGPGVVRAAGRGVSAGVPIPQAPGG 271

Query: 127 LAGPVRGVGGPSQQVMTPQGR 147
           LAGPV GVGGPSQQVMTPQ R
Sbjct: 272 LAGPVPGVGGPSQQVMTPQRR 292



 Score = 30.4 bits (67), Expect = 1.4
 Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 4/44 (9%)

Query: 200 GPPMGIPPGRGTPMGMP----PPGMRPPPPGMRGPPPPGMRPPR 239
           GP +    GRG   G+P    P G+  P PG+ GP    M P R
Sbjct: 248 GPGVVRAAGRGVSAGVPIPQAPGGLAGPVPGVGGPSQQVMTPQR 291


>gi|169215637 PREDICTED: similar to hCG2041320 [Homo sapiens]
          Length = 318

 Score =  234 bits (597), Expect = 5e-62
 Identities = 114/141 (80%), Positives = 123/141 (87%)

Query: 7   SKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRV 66
           +++ QHIDYRM+CILQ+G IF G FKAFDKH+NLILCDCDEFRKIKPKN KQ E EEK  
Sbjct: 152 ARLQQHIDYRMKCILQEGTIFFGIFKAFDKHVNLILCDCDEFRKIKPKNVKQPELEEKHF 211

Query: 67  LGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAG 126
            GLVLL GENLVSMTVEG PPK TGIARVPLAGAAGGPG+ RAAGRG+ AGVP+PQAP G
Sbjct: 212 WGLVLLHGENLVSMTVEGLPPKYTGIARVPLAGAAGGPGVVRAAGRGVSAGVPIPQAPGG 271

Query: 127 LAGPVRGVGGPSQQVMTPQGR 147
           LAGPV GVGGPSQQVMTPQ R
Sbjct: 272 LAGPVPGVGGPSQQVMTPQRR 292



 Score = 30.4 bits (67), Expect = 1.4
 Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 4/44 (9%)

Query: 200 GPPMGIPPGRGTPMGMP----PPGMRPPPPGMRGPPPPGMRPPR 239
           GP +    GRG   G+P    P G+  P PG+ GP    M P R
Sbjct: 248 GPGVVRAAGRGVSAGVPIPQAPGGLAGPVPGVGGPSQQVMTPQR 291


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 80.1 bits (196), Expect = 2e-15
 Identities = 60/144 (41%), Positives = 61/144 (42%), Gaps = 24/144 (16%)

Query: 113 GIPAGVPMPQAPAGLAG---PVRGVGGPSQ--------QVMTPQGR---GTVAAAAAAAT 158
           GIP  +P P  P G AG   P  G  G               P G    G      A   
Sbjct: 256 GIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHG 315

Query: 159 ASIAGAPTQYPPGRGGPPPPMGRGAPPPGM--MGPPPGMRPPMGPPMGIPPGRGTPMGMP 216
               G P   PPG GG PPP     PPPGM   GPPP   PP GPP G P G   P  MP
Sbjct: 316 PHGLGHPHAGPPGSGGQPPP----RPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGP--MP 369

Query: 217 PPGMRPPPPGMRGPPPPGMRPPRP 240
           P GMR PPP M  PP     PPRP
Sbjct: 370 PHGMRGPPPLM--PPHGYTGPPRP 391



 Score = 69.7 bits (169), Expect = 2e-12
 Identities = 67/192 (34%), Positives = 72/192 (37%), Gaps = 67/192 (34%)

Query: 85  PPPKDTGIAR--VPLAGA--AGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQ 140
           PPP   G A    P AG   AG PG G +         P P  P G+  P     G SQ 
Sbjct: 263 PPPMPPGAAGHGPPSAGTPGAGHPGHGHSH--------PHPFPPGGMPHP-----GMSQM 309

Query: 141 VMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMM--GPPPGMRPP 198
            +   G   +            G P   PPG GG PPP     PPPGM   GPPP   PP
Sbjct: 310 QLAHHGPHGL------------GHPHAGPPGSGGQPPPR----PPPGMPHPGPPPMGMPP 353

Query: 199 MGPPMGIPPGRGTPMGMPPPGMRPPPPGM----------------------------RGP 230
            GPP G P G   PM  PP GMR PPP M                            R P
Sbjct: 354 RGPPFGSPMGHPGPM--PPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPP 411

Query: 231 PPP--GMRPPRP 240
            PP   +R P P
Sbjct: 412 VPPRGPLRGPLP 423



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 36/97 (37%), Positives = 42/97 (43%), Gaps = 9/97 (9%)

Query: 148 GTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPP-----GMMGPPPGMRPPMGPP 202
           G+ A    AA   ++ A   +      PPPP    AP P     G   PPPGM PP   P
Sbjct: 188 GSAAERLLAAQNPLSQADRPHQLFADAPPPP---SAPNPVVSSLGSGLPPPGMPPPGSFP 244

Query: 203 MGIPPGRGTPMGMPPPGMRPP-PPGMRGPPPPGMRPP 238
             +PP    P G+PP    PP PPG  G  PP    P
Sbjct: 245 PPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTP 281



 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 43/131 (32%), Positives = 46/131 (35%), Gaps = 56/131 (42%)

Query: 162 AGAPTQYPPGRGGPPPPMGRGAPPPGMMGP--PPGMRPP--------MGPPMGIPPGRG- 210
           +G P    P  G  PPP+    PPPG + P  PP M PP         GPP    PG G 
Sbjct: 230 SGLPPPGMPPPGSFPPPV----PPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGH 285

Query: 211 -----------TPMGMPPPGMRP----------------------------PPPGM--RG 229
                       P GMP PGM                              PPPGM   G
Sbjct: 286 PGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPG 345

Query: 230 PPPPGMRPPRP 240
           PPP GM P  P
Sbjct: 346 PPPMGMPPRGP 356



 Score = 37.4 bits (85), Expect = 0.012
 Identities = 26/75 (34%), Positives = 31/75 (41%), Gaps = 11/75 (14%)

Query: 167 QYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGP-PMGIPPGRGTPMGMPPPGMRPPPP 225
           Q P  +   P  +   APPP     P    P +     G+PP       MPPPG  PPP 
Sbjct: 198 QNPLSQADRPHQLFADAPPP-----PSAPNPVVSSLGSGLPPPG-----MPPPGSFPPPV 247

Query: 226 GMRGPPPPGMRPPRP 240
              G  PPG+ P  P
Sbjct: 248 PPPGALPPGIPPAMP 262


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 75.5 bits (184), Expect = 4e-14
 Identities = 41/81 (50%), Positives = 46/81 (56%), Gaps = 4/81 (4%)

Query: 163 GAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPPG--RGTPMGMPP-PG 219
           G PT  PPG     PP  R    PG+ GP P + PP GPP G PPG   G P G+PP P 
Sbjct: 425 GPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPP-GPPPGRPPGPPPGPPPGLPPGPP 483

Query: 220 MRPPPPGMRGPPPPGMRPPRP 240
            R PPP +  P PPG+ PPRP
Sbjct: 484 PRGPPPRLPPPAPPGIPPPRP 504



 Score = 70.1 bits (170), Expect = 2e-12
 Identities = 60/161 (37%), Positives = 70/161 (43%), Gaps = 46/161 (28%)

Query: 84  GPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGP-VRGVGGPSQQVM 142
           GPPP   G    P     G P        G+P G P P AP  L  P + G+ GP  +++
Sbjct: 409 GPPP--LGPPPAPPLRPPGPP-------TGLPPGPP-PGAPPFLRPPGMPGLRGPLPRLL 458

Query: 143 TPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPP 202
            P                  G P   PPG    PPP     PPPG+   PPG  PP GPP
Sbjct: 459 PP------------------GPPPGRPPG----PPP----GPPPGL---PPGP-PPRGPP 488

Query: 203 MGIPPGRGTPMGMPPPG---MRPPPPGMRGPPPPGMRPPRP 240
             +PP    P G+PPP    MRPP     GP PPG+ PP P
Sbjct: 489 PRLPP--PAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAP 527



 Score = 33.5 bits (75), Expect = 0.17
 Identities = 22/54 (40%), Positives = 26/54 (48%), Gaps = 12/54 (22%)

Query: 191 PPPGMRPPM--------GPP---MGIPPGRGTPMGMPPPGMRPPPPGMRGPPPP 233
           P PG +PP         GPP   + I P  G  +   PPG +PP P   GPPPP
Sbjct: 157 PLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGP-PPGPPPP 209



 Score = 28.5 bits (62), Expect = 5.4
 Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 10/93 (10%)

Query: 120 MPQAPAGLAG---PVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPP 176
           MP AP+ +     P+ G   PS    T    G    A +       G P + PPGR  P 
Sbjct: 144 MPHAPSNILIQDIPLPGAQPPSILKKT-SAYGPPTRAVSILPLLGHGVP-RLPPGRKPPG 201

Query: 177 PPMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGR 209
           PP G   PPP  +    G +  +G  + +PP R
Sbjct: 202 PPPG---PPPPQVVQMYGRK--VGFALDLPPRR 229



 Score = 28.5 bits (62), Expect = 5.4
 Identities = 20/60 (33%), Positives = 25/60 (41%), Gaps = 11/60 (18%)

Query: 182 GAPPPGMMGPPPGMRPPMGPPMGIPP-GRGTPMGMPPPGMRPPPPGMRGP-PPPGMRPPR 239
           GA PP ++       PP      +P  G G P           PPG + P PPPG  PP+
Sbjct: 160 GAQPPSILKKTSAYGPPTRAVSILPLLGHGVPR---------LPPGRKPPGPPPGPPPPQ 210


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 72.8 bits (177), Expect = 3e-13
 Identities = 67/183 (36%), Positives = 76/183 (41%), Gaps = 32/183 (17%)

Query: 85   PPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTP 144
            PP    GI  +P    AG P      G  IP   P+P A   L  P+ G G P    +  
Sbjct: 924  PPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPG 983

Query: 145  QGRGTVAAAAAAATASI-----AGAPTQYP-PGRGGPPPPM--GRGAPPP------GMMG 190
             G         A          AG P   P PG G PPPP   G G PPP      G+  
Sbjct: 984  AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1043

Query: 191  PPP----GMRPPMGPPM---GIPPGRGTP-MGMPPPGMRPPPPGMRGPPPP-----GMRP 237
            PPP    G+ PP  PP+   GIPP    P  G+PPP   PP PG   PPPP     G+ P
Sbjct: 1044 PPPLPGAGIPPP--PPLPGAGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPP 1098

Query: 238  PRP 240
            P P
Sbjct: 1099 PPP 1101



 Score = 71.6 bits (174), Expect = 6e-13
 Identities = 64/176 (36%), Positives = 71/176 (40%), Gaps = 29/176 (16%)

Query: 85   PPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTP 144
            PP    GI   P    AG P      G GIP   P+P A      P+ G G P    +  
Sbjct: 1034 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1093

Query: 145  QGRGTVAAAAAAATASIAGAPTQYP-PGRGGPPPPM--GRGAPPP------GMMGPPPGM 195
             G                G P   P PG G PPPP   G G PPP      G+  PPP  
Sbjct: 1094 AGIPPPPPLPGV------GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1147

Query: 196  R-----PPMGPPMGIPPGRGTP-MGMPPPGMRPPPPGMRGPPPP-----GMRPPRP 240
            R     PP  P  GIPP    P  G+PPP   PP PG+  PPPP     G+ PP P
Sbjct: 1148 RVGIPPPPPLPGAGIPPPPPLPGAGIPPP---PPLPGVGIPPPPPLPGVGIPPPPP 1200



 Score = 61.6 bits (148), Expect = 6e-10
 Identities = 64/178 (35%), Positives = 74/178 (41%), Gaps = 36/178 (20%)

Query: 77   LVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGG 136
            L S  +  PPP   G   +P       P      G GIP   P+P A      P+ G G 
Sbjct: 891  LPSTAIPQPPPLQ-GTEMLP-------PPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGI 942

Query: 137  PSQQVMTPQGRGTVAAAAAAATASIAGAPTQYP-PGRGGPPPPMGRGAPPPGMMGPPP-- 193
            P    +        AA         AG P   P PG G PPPP   GA   G+  PPP  
Sbjct: 943  PPPPPLPG------AAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGA---GIPPPPPLP 993

Query: 194  --GMRPPMGPPM---GIPPGRGTP-MGMPPPGMRPPPPGMRGPPPP-----GMRPPRP 240
              G+ PP  PP+   GIPP    P  G+PPP   PP PG   PPPP     G+ PP P
Sbjct: 994  GAGIPPP--PPLPGAGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPPPPP 1046



 Score = 54.7 bits (130), Expect = 7e-08
 Identities = 55/173 (31%), Positives = 62/173 (35%), Gaps = 27/173 (15%)

Query: 85   PPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTP 144
            PP    GI   P     G P      G GIP   P+P A      P+ GVG P    +  
Sbjct: 1133 PPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPG 1192

Query: 145  QGRGTVAAAAAAATASIAGAPTQYP-PGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPM 203
             G         A      G P   P PG G PP P     PPPG   PPP + P  GPP+
Sbjct: 1193 VGIPPPPPLPGA------GIPPPPPLPGMGIPPAP-APPLPPPGTGIPPPPLLPVSGPPL 1245

Query: 204  GIPPGRGTPMGMPPP---GMRPPP-------------PGMRGPPPPGMRPPRP 240
                G  T   +P P   G  PPP              G R  P    RP +P
Sbjct: 1246 LPQVGSST---LPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKP 1295



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 49/157 (31%), Positives = 60/157 (38%), Gaps = 30/157 (19%)

Query: 114  IPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPP--- 170
            IP+  P+P   +  + P  G+  P    +      T+ + A      + G     PP   
Sbjct: 855  IPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPP 914

Query: 171  --GRGGPPPPM-------------GRGAPPP----GMMGPPPGMRPPMGPPMGIP-PGRG 210
              G G PPPP              G G PPP    G   PPP   P  G P+  P PG G
Sbjct: 915  LPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAG 974

Query: 211  TPMGMPPPGMR-PPPPGMRG------PPPPGMRPPRP 240
             P   P PG   PPPP + G      PP PG   P P
Sbjct: 975  IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1011


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score = 72.8 bits (177), Expect = 3e-13
 Identities = 65/168 (38%), Positives = 71/168 (42%), Gaps = 35/168 (20%)

Query: 97  LAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAA 156
           L G  G PG     GR  P+GV  PQ   G  GP    G P   V   Q  G      A 
Sbjct: 606 LDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVV---QQEGLKGEQGAP 662

Query: 157 ATASIAGAPTQYPPGRGGPPPPMGRGAPP--------PGMMGPPP-----GMRPPMGPPM 203
                 GAP   PPG  GP  P GR  PP         G MGPP      G++ P GPP 
Sbjct: 663 GPRGHQGAPG--PPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPP- 719

Query: 204 GIP--PGRGTPMGMPP----PGMRPPPPGMRGPP-------PPGMRPP 238
           G+P  PG G   G+P     PG +P PPG  GPP       PPG  PP
Sbjct: 720 GVPGPPGPGGSPGLPGEIGFPG-KPGPPGPTGPPGKDGPNGPPG--PP 764



 Score = 65.1 bits (157), Expect = 5e-11
 Identities = 70/230 (30%), Positives = 80/230 (34%), Gaps = 68/230 (29%)

Query: 58  QAEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGI-GRAAGRGIPA 116
           Q E+ EK  LGL              GPP +D         G  G PG+ G    RG   
Sbjct: 526 QGEKGEKGSLGL-------------PGPPGRDGSKGMRGEPGELGEPGLPGEVGMRG--- 569

Query: 117 GVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAP----TQYPPGR 172
               PQ P GL GP   VG P  Q    + +GT             G P     Q  PG 
Sbjct: 570 ----PQGPPGLPGPPGRVGAPGLQGERGE-KGTRGEKGERGLDGFPGKPGDTGQQGRPGP 624

Query: 173 GGPPPPMGR-----GAPPPGMMGP------------------------PPGMRPPMGP-- 201
            G   P G       A PPG+ G                         PPG R P+GP  
Sbjct: 625 SGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEG 684

Query: 202 ---PMGIPPGRGTPMGMPPPGM--------RPPPPGMRGPPPPGMRPPRP 240
              P G+   RG    M PPG+         P PPG+ GPP PG  P  P
Sbjct: 685 RDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLP 734



 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 59/177 (33%), Positives = 68/177 (38%), Gaps = 33/177 (18%)

Query: 84   GPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMT 143
            GPP  D       +AGAAG PGI  + G+    G P PQ P+GL G + G  G   +   
Sbjct: 1201 GPPGADG------IAGAAGPPGIQGSPGK---EGPPGPQGPSGLPG-IPGEEGKEGRDGK 1250

Query: 144  PQGRGTVAAAAAAATASIAGAPTQYPP------GRGGPPPPMGRGAPP--PGMMGPP--- 192
            P   G    A         GA  + PP      G  G P P G       PG  G P   
Sbjct: 1251 PGPPGEPGKAGEPGLPGPEGA--RGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKD 1308

Query: 193  --PGMRPPMGP--PMGIPPGRGTP--MGMPPPGMRPPPPGMRG----PPPPGMRPPR 239
               G   P GP  P G P   G+P   G P P   P   G +G    P  PG   PR
Sbjct: 1309 GDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPR 1365



 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 51/169 (30%), Positives = 60/169 (35%), Gaps = 36/169 (21%)

Query: 98   AGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAA 157
            +GA G PG     G+    G   PQ P G  GP    G P      P   GT     +  
Sbjct: 1293 SGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPG-EPGPSGTPGQKGSKG 1351

Query: 158  TASIAGAPTQYPPGRGGPPPPMGRGAPP----PGMMGPP--------PGMRPPMGPP--- 202
                 G P    P RG P  P  +G P     PG  G P        PG++   GPP   
Sbjct: 1352 ENGSPGLPGFLGP-RGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGK 1410

Query: 203  -----MGIP--------------PGRGTPMGMPPPGMRPPPPGMRGPPP 232
                  GIP              PG   P+G P P  +P  PG+RG  P
Sbjct: 1411 GQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESP 1459



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 55/165 (33%), Positives = 64/165 (38%), Gaps = 19/165 (11%)

Query: 82   VEGPPPKDTGIARVPLAGAAGGPG-IGRAAGRGIPAGVPMPQAPAGLAGP-VRGVGGPSQ 139
            + G P KD        AG  G PG +G     G P G+P P        P +RG  G   
Sbjct: 941  LRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAP-GLPGPPGKGKDGEPGLRGSPGLPG 999

Query: 140  QVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPM 199
             + T    G V  +   A         +  PG  G P    RG P  G+ GPP     P 
Sbjct: 1000 PLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPG--SRGDPGIGVAGPP----GPS 1053

Query: 200  GPP--MGIPPGRGTPMGMPPP------GMRPPPPGMRGPP-PPGM 235
            GPP   G P  RG P G P P         P  PG RGPP  PG+
Sbjct: 1054 GPPGDKGSPGSRGLP-GFPGPQGPAGRDGAPGNPGERGPPGKPGL 1097



 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 56/199 (28%), Positives = 74/199 (37%), Gaps = 56/199 (28%)

Query: 89   DTGIARVPLAGAAGGPGI-GRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGR 147
            D GI      G +G PG  G    RG+P G P PQ PAG  G     G P ++   P G+
Sbjct: 1041 DPGIGVAGPPGPSGPPGDKGSPGSRGLP-GFPGPQGPAGRDG---APGNPGER--GPPGK 1094

Query: 148  GTVAAAAAAATASIAGAP--TQYPPGRGGPPPPMG----RGAP----------------P 185
              +++  +    ++         PPG  G P   G    +G P                P
Sbjct: 1095 PGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGP 1154

Query: 186  PGMMGPP-----------------PGMRPPMGPPMGIPPGRGTPMGMPPPGM-----RPP 223
            PG+ GPP                  G +   G P G+P   G P    PPG         
Sbjct: 1155 PGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHP-GVPGFMGPPGNPGPPGADGIAGAAG 1213

Query: 224  PPGMRGPP----PPGMRPP 238
            PPG++G P    PPG + P
Sbjct: 1214 PPGIQGSPGKEGPPGPQGP 1232



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 53/171 (30%), Positives = 64/171 (37%), Gaps = 44/171 (25%)

Query: 78  VSMTVEGPPPKDTGIARVPLAGA--------------AGGPGIGRAAGRGIPAGVPMPQA 123
           V++  E PPP      R P  G+              AG  G    AG   P G+P P+ 
Sbjct: 445 VTVVTEPPPPPPP--QRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAG---PMGLPGPKG 499

Query: 124 PAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGA 183
             G  GPV G  GP  +     G G           S+ G P   PPGR G     G   
Sbjct: 500 DIGAIGPV-GAPGPKGE-KGDVGIGPFGQGEKGEKGSL-GLPG--PPGRDGSKGMRGE-- 552

Query: 184 PPPGMMGPP-----PGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
             PG +G P      GMR P GPP           G+P P  R   PG++G
Sbjct: 553 --PGELGEPGLPGEVGMRGPQGPP-----------GLPGPPGRVGAPGLQG 590



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 56/189 (29%), Positives = 63/189 (33%), Gaps = 44/189 (23%)

Query: 83   EGPPPKDTGIARVPLAGAAGGPGIGRAAGRG----IPAGV--PMPQAPAGLAGPVRGVGG 136
            +GP  +D         G  G PG+      G    +   V    P  P GL G + G  G
Sbjct: 1074 QGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPG-LPGFKG 1132

Query: 137  PSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG-RGAPP---------- 185
                   P   GT      A    + G     PPG  GP    G RGA            
Sbjct: 1133 DKGVPGKPGREGTEGKKGEAGPPGLPG-----PPGIAGPQGSQGERGADGEVGQKGDQGH 1187

Query: 186  ---PGMMGPPPGMRPP--------MGPPMGI--PPGRGTPMGMPPPGMRPPPPGMRG--- 229
               PG MGPP    PP         GPP GI   PG+  P G   P   P  PG  G   
Sbjct: 1188 PGVPGFMGPPGNPGPPGADGIAGAAGPP-GIQGSPGKEGPPGPQGPSGLPGIPGEEGKEG 1246

Query: 230  ----PPPPG 234
                P PPG
Sbjct: 1247 RDGKPGPPG 1255



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 69/222 (31%), Positives = 83/222 (37%), Gaps = 56/222 (25%)

Query: 60  EREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGI-------GRAAGR 112
           ER E  + G   LRGE  +        P + G A +P  GA G PG+       G     
Sbjct: 772 ERGEDGLPGKPGLRGE--IGEQGLAGRPGEKGEAGLP--GAPGFPGVRGEKGDQGEKGEL 827

Query: 113 GIPAGVPMPQAPAGLAGPVRGVGGP-SQQVMTPQGR--GTVAAAAAAATASIAGAP-TQY 168
           G+P G+   +   G AGP    G P +  + TP  R  G            + G P  Q 
Sbjct: 828 GLP-GLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQG 886

Query: 169 PPGR---GGPPPPMG-------RGAP-------PPGMMGPPPGMRPPMGPP--MGIPPGR 209
            PG     GP  P G        GAP        PG +G P     P GPP  +G P  R
Sbjct: 887 RPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAP----GPSGPPGSVGAPGLR 942

Query: 210 GTP--------------MGMP-PPGMR--PPPPGMRGPPPPG 234
           GTP               G P P G R  P  PG+ GPP  G
Sbjct: 943 GTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKG 984



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 54/193 (27%), Positives = 61/193 (31%), Gaps = 61/193 (31%)

Query: 99   GAAGGPGI-GRAAGRGI--PAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQ----GRGTVA 151
            G  G PGI G     G+  P G+P    P G  GP    G P  +  +P      R    
Sbjct: 1411 GQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQE 1470

Query: 152  AAAAAATASIAGAPTQYPP-------GRGGPPPPMGRGAPP-----------PGMMG--- 190
                     +A    Q PP       GR GPP P G+   P           PG  G   
Sbjct: 1471 ELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEG 1530

Query: 191  -------------------PPPGMRPPMGPPMGIP-------------PGRGTPMGMPPP 218
                               P  G+R  MGPP GIP             PG   P G   P
Sbjct: 1531 PSGPIGPKGERGAKGDPGAPGVGLRGEMGPP-GIPGQPGEPGYAKDGLPGIPGPQGETGP 1589

Query: 219  GMRPPPPGMRGPP 231
               P  PG  GPP
Sbjct: 1590 AGHPGLPGPPGPP 1602



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 37/120 (30%), Positives = 42/120 (35%), Gaps = 19/120 (15%)

Query: 99   GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAAT 158
            G  G PG     GR  P G P      GL GP   +G        P+G         A  
Sbjct: 1500 GPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIG--------PKGERGAKGDPGAPG 1551

Query: 159  ASIAGAPTQYPPGRGGPPPPMG---RGAP----PPGMMGPP--PGMRPPMGPPMGIPPGR 209
              + G     PPG  G P   G    G P    P G  GP   PG+  P GPP    P +
Sbjct: 1552 VGLRG--EMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQ 1609



 Score = 37.4 bits (85), Expect = 0.012
 Identities = 38/119 (31%), Positives = 40/119 (33%), Gaps = 18/119 (15%)

Query: 84   GPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMT 143
            GPP KD    R    G  G PG G   G   P+G   P  P G  G     G P      
Sbjct: 1503 GPPGKDGLPGRAGPMGEPGRPGQGGLEG---PSG---PIGPKGERGAKGDPGAP------ 1550

Query: 144  PQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPP--PGMMGP--PPGMRPP 198
              G G              G P     G  G P P G   P   PG+ GP  PPG   P
Sbjct: 1551 --GVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDP 1607



 Score = 30.4 bits (67), Expect = 1.4
 Identities = 31/105 (29%), Positives = 38/105 (36%), Gaps = 31/105 (29%)

Query: 161 IAGAPTQYPPGRGGPPPPMGRGAPPPGM----------MGPPPGMRPPMG--PPMGIPPG 208
           I   P Q       PPPP  +  P PG              P G +  MG   PMG+P  
Sbjct: 438 IPSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGP 497

Query: 209 RGT-----PMGMPPP-------GMRPPPPGMRG-------PPPPG 234
           +G      P+G P P       G+ P   G +G       P PPG
Sbjct: 498 KGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPG 542



 Score = 30.4 bits (67), Expect = 1.4
 Identities = 29/83 (34%), Positives = 34/83 (40%), Gaps = 14/83 (16%)

Query: 89   DTGIARVPLAGAAGGPGIGRAAGR------GIPAGVPMPQAPAGLAGPVRGVGGPSQQVM 142
            D G   V L G  G PGI    G       G+P G+P PQ   G AG   G+ GP     
Sbjct: 1546 DPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLP-GIPGPQGETGPAGH-PGLPGP----- 1598

Query: 143  TPQGRGTVAAAAAAATASIAGAP 165
             P   G    +  A  AS+A  P
Sbjct: 1599 -PGPPGQCDPSQCAYFASLAARP 1620


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score = 72.4 bits (176), Expect = 3e-13
 Identities = 52/149 (34%), Positives = 66/149 (44%), Gaps = 20/149 (13%)

Query: 101 AGGPGIGRAAG---RGIPAGVPMPQA-----PAGLAGPVRGVGGPSQQVMTPQGRGTVAA 152
           AG PG+ R       G+P   P+P++     P GL  P     GP+     P G      
Sbjct: 225 AGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPA-----PSGPPGPPQ 279

Query: 153 AAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGI-PPGRGT 211
               A      AP  +PP  G  PP  G   P PG+  P PG+ PP     G+ PP  G 
Sbjct: 280 LPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTS---GVHPPAPG- 335

Query: 212 PMGMPPPGMRPPPPGMRGPPPPGMRPPRP 240
            +  P PG+ PP PG+  PP PG+ PP P
Sbjct: 336 -VHPPAPGVHPPAPGVH-PPAPGVHPPAP 362



 Score = 65.1 bits (157), Expect = 5e-11
 Identities = 59/175 (33%), Positives = 73/175 (41%), Gaps = 28/175 (16%)

Query: 85  PPPKDTGIARVPLAGAA--GGPGIGR----AAGRGIPAGVPMPQAPAGLAGPVRGVGGPS 138
           PPP    +  +P  G A  G PG  +    A G   PA V  P A +G+  P  GV  P+
Sbjct: 254 PPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPA-SGVHPPAPGVHPPA 312

Query: 139 QQVMTPQGRGTVAAAAAAATASI-AGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRP 197
             V  P      A      T+ +   AP  +PP  G  PP  G   P PG+  P PG+ P
Sbjct: 313 PGVHPP------APGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHP 366

Query: 198 PMGPPMGI-PPGRGTPMGMP-----PPGMRPPPPGMR------GPPPPGMRPPRP 240
           P  P  G+ P   G     P      PG+ PP PGM        P PPG+ P  P
Sbjct: 367 P--PSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAP 419



 Score = 54.7 bits (130), Expect = 7e-08
 Identities = 45/134 (33%), Positives = 54/134 (40%), Gaps = 18/134 (13%)

Query: 109 AAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQY 168
           A G   PA    P AP G+  P  GV  P+  V  P   G    A     A    AP  +
Sbjct: 333 APGVHPPAPGVHPPAP-GVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPA----APAVH 387

Query: 169 PPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMR 228
           P   G  PP  G     PG+   PPG+ P      G+ P         PPG+ P  PG+ 
Sbjct: 388 PQAPGVHPPAPGMHPQAPGVHPQPPGVHP---SAPGVHP--------QPPGVHPSNPGVH 436

Query: 229 GPP--PPGMRPPRP 240
            P   PP +RPP P
Sbjct: 437 PPTPMPPMLRPPLP 450



 Score = 54.7 bits (130), Expect = 7e-08
 Identities = 43/123 (34%), Positives = 51/123 (41%), Gaps = 7/123 (5%)

Query: 109 AAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAA---ATASIAGAP 165
           A G   PA    P AP G+  P  GV  P    + PQ  G   AA A    A      AP
Sbjct: 340 APGVHPPAPGVHPPAP-GVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAP 398

Query: 166 TQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPP---MGPPMGIPPGRGTPMGMPPPGMRP 222
             +P   G  P P G     PG+   PPG+ P    + PP  +PP    P+    PG  P
Sbjct: 399 GMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIP 458

Query: 223 PPP 225
           PPP
Sbjct: 459 PPP 461



 Score = 54.3 bits (129), Expect = 9e-08
 Identities = 31/76 (40%), Positives = 37/76 (48%), Gaps = 10/76 (13%)

Query: 175 PPPPMGRGAPPPGMMGPPPGM------RPPMGPPMGIPPGRGTPM-GMPPPG---MRPPP 224
           PP P    A PPG+  PPP +      RPP+   +  PP  G P+  MPP G     PP 
Sbjct: 217 PPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPG 276

Query: 225 PGMRGPPPPGMRPPRP 240
           P    PP PG+ PP P
Sbjct: 277 PPQLPPPAPGVHPPAP 292



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 28/72 (38%), Positives = 36/72 (50%), Gaps = 10/72 (13%)

Query: 179 MGRGAPPPGMMGPPPGMRPPMGPPM-GIPPGRGTPMGMPPP---GMRPPP-----PGMRG 229
           M +   PP +   PPG++ P  P M G+PP    P  +PPP   G+  PP     P   G
Sbjct: 214 MEKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSG 273

Query: 230 PP-PPGMRPPRP 240
           PP PP + PP P
Sbjct: 274 PPGPPQLPPPAP 285


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 57/174 (32%), Positives = 69/174 (39%), Gaps = 20/174 (11%)

Query: 83  EGPPPKDTG---IARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAG-PVRGVGGPS 138
           +GPPP+       AR P     G P  G    +G P     PQ P    G   +G   P 
Sbjct: 222 QGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 281

Query: 139 QQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRG----GPPPPMGRGAPPPGMMGPPPG 194
           +    PQG      + + ++ S  G P   PP  G    GPPPP G+   PP   G  P 
Sbjct: 282 K----PQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 337

Query: 195 MRPPMGPPMGIPP--GRGTPMGMPPPGMRPPPPGMRG------PPPPGMRPPRP 240
             PP G P G PP  G  +     PPG    PP   G      PPP G  P +P
Sbjct: 338 GPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP 391



 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 66/193 (34%), Positives = 79/193 (40%), Gaps = 40/193 (20%)

Query: 83  EGPPPKD--TGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAG-PVRGVGGPSQ 139
           +GPPP+   +   R P     G P  G    +G P     PQ P    G   +G   P +
Sbjct: 99  QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 158

Query: 140 QVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRG----GPPPPMG-------------RG 182
               PQG        + ++ S  G P   PP  G    GPPPP G             +G
Sbjct: 159 ----PQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 214

Query: 183 APPPGM-MGPPP-------GMRPPMGPPMGIPP-GRGTPMGMPPPGMRP--PPP----GM 227
            PPPG   GPPP         R P G P G PP G   P G PPP  +P  PPP      
Sbjct: 215 PPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 274

Query: 228 RGPPPPGMRPPRP 240
           +GPPPPG +P  P
Sbjct: 275 QGPPPPG-KPQGP 286



 Score = 66.2 bits (160), Expect = 2e-11
 Identities = 54/184 (29%), Positives = 70/184 (38%), Gaps = 20/184 (10%)

Query: 76  NLVSMTVEGPPPKDTGIARVPLAGAA---GGPGIGRAAGRGIPAGVPMPQAPAGLAGPVR 132
           +L++   +G PP+     + P +      G P  G    +G P     PQ P    G   
Sbjct: 30  SLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 89

Query: 133 GVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPP 192
               P  +   P  +G  + +  +      G P Q      GPPPP G+   PP   G  
Sbjct: 90  QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 149

Query: 193 PGMRPPMGPPMGIPP-----------GRGTPMGMPPPGMR-----PPPPGM-RGPPPPGM 235
           P   PP G P G PP             G P G PP G       PPPPG  +GPPP G 
Sbjct: 150 PQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 209

Query: 236 RPPR 239
             P+
Sbjct: 210 NKPQ 213



 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 50/151 (33%), Positives = 62/151 (41%), Gaps = 33/151 (21%)

Query: 109 AAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQY 168
           ++ + +   V   ++P+ +AG  +G   P Q    PQG             S  G P   
Sbjct: 14  SSAQNLNEDVSQEESPSLIAGNPQGA--PPQGGNKPQG-----------PPSPPGKPQGP 60

Query: 169 PPGRG----GPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPP----------GRGTPMG 214
           PP  G    GPPPP G+   PP   G  P   PP G P G PP            G P G
Sbjct: 61  PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG 120

Query: 215 MPPPGMR-----PPPPGM-RGPPPPGMRPPR 239
            PP G       PPPPG  +GPPP G   P+
Sbjct: 121 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 151



 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 58/172 (33%), Positives = 63/172 (36%), Gaps = 21/172 (12%)

Query: 83  EGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVM 142
           +GPPP+     + P     G P      G   P G P P  P G          P     
Sbjct: 58  QGPPPQGGNQPQGP-PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPG 116

Query: 143 TPQGRGTVAAAAAAATASIAGAPTQYPPGRG----GPPPP-MGRGAPPPG------MMGP 191
            PQG                G P   PP  G    GPPPP   +G PP G         P
Sbjct: 117 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSP 176

Query: 192 P--PGMRPPMG--PPMGIPPGRGTPMGMPPPG----MRPPPPGM-RGPPPPG 234
           P  P   PP G   P G PP  G P G PP G      PPPPG  +GPPP G
Sbjct: 177 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 228



 Score = 62.0 bits (149), Expect = 4e-10
 Identities = 59/176 (33%), Positives = 68/176 (38%), Gaps = 28/176 (15%)

Query: 83  EGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVM 142
           +GPPP+     + P     G P      G   P G P P  P G   P +G    SQ   
Sbjct: 181 QGPPPQGGNQPQGP-PPPPGKPQGPPPQGGNKPQGPPPPGKPQG--PPPQG-DNKSQSAR 236

Query: 143 TPQGRGTVAAAAAAATASIAGAPT---QYPPGRGG------PPPPMGRGAPPPG------ 187
           +P G+                 P    Q PP +GG      PPP   +G PP G      
Sbjct: 237 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRS 296

Query: 188 MMGPP--PGMRPPMG--PPMGIPPGRGTPMGMPPPG----MRPPPPGM-RGPPPPG 234
              PP  P   PP G   P G PP  G P G PP G      PPPPG  +GPPP G
Sbjct: 297 SRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 352



 Score = 35.8 bits (81), Expect = 0.034
 Identities = 21/48 (43%), Positives = 24/48 (50%), Gaps = 7/48 (14%)

Query: 200 GPPMGIPP-GRGTPMGMPPPGMRP--PPP----GMRGPPPPGMRPPRP 240
           G P G PP G   P G P P  +P  PPP      +GPPPP  +P  P
Sbjct: 34  GNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 81


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 55/175 (31%), Positives = 67/175 (38%), Gaps = 18/175 (10%)

Query: 83  EGPPPKD--TGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQ 140
           +GPPP+   +   R P     G P  G    +G P     PQ P    G       P  +
Sbjct: 78  QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGK 137

Query: 141 VMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMG 200
              P  +G  + +  +      G P Q      GPPPP G+   PP   G  P   PP G
Sbjct: 138 PQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPG 197

Query: 201 PPMGIPP----------GRGTPMGMPPPGMR-----PPPPGM-RGPPPPGMRPPR 239
            P G PP            G P G PP G       PPPPG  +GPPP G   P+
Sbjct: 198 KPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 252



 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 51/169 (30%), Positives = 65/169 (38%), Gaps = 12/169 (7%)

Query: 83  EGPPPKD--TGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQ 140
           +GPPP+   +   R P     G P  G    +G P     PQ P    G       P  +
Sbjct: 139 QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGK 198

Query: 141 VMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMG 200
              P  +G  + ++ +      G P Q      GPPPP G+   PP   G  P   PP G
Sbjct: 199 PQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 258

Query: 201 PPMGIPPGRG---TPMGMPPPGMRPPPPGMRG------PPPPGMRPPRP 240
            P G PP +G   +     PPG    PP   G      PPP G  P +P
Sbjct: 259 KPQG-PPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP 306



 Score = 65.1 bits (157), Expect = 5e-11
 Identities = 51/159 (32%), Positives = 60/159 (37%), Gaps = 20/159 (12%)

Query: 101 AGGPGIGRAAGRGIPAGVP----MPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAA 156
           AG P      G   P G P     PQ P    G       P  +   P  +G  + +  +
Sbjct: 33  AGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS 92

Query: 157 ATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPP--------- 207
                 G P Q      GPPPP G+   PP   G  P   PP G P G PP         
Sbjct: 93  PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPR 152

Query: 208 -GRGTPMGMPPPGMR-----PPPPGM-RGPPPPGMRPPR 239
              G P G PP G       PPPPG  +GPPP G + P+
Sbjct: 153 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQ 191



 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 43/90 (47%), Positives = 47/90 (52%), Gaps = 19/90 (21%)

Query: 169 PPGRGGPPPPMG----RGAPPPGM-MGPPP------GMRPPMGPPMGIPP-GRGTPMGMP 216
           PPG+   PPP G    +G PPPG   GPPP        R P G P G PP G   P G P
Sbjct: 53  PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP 112

Query: 217 PPGMRP--PPP--GMR--GPPPPGMRPPRP 240
           PP  +P  PPP  G R  GPPPPG +P  P
Sbjct: 113 PPPGKPQGPPPQGGNRPQGPPPPG-KPQGP 141



 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 40/99 (40%), Positives = 43/99 (43%), Gaps = 20/99 (20%)

Query: 161 IAGAPTQYPPGRG----GPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPP--------- 207
           IAG P    P  G    GPPPP G+   PP   G  P   PP G P G PP         
Sbjct: 32  IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 91

Query: 208 -GRGTPMGMPPPGMR-----PPPPGM-RGPPPPGMRPPR 239
              G P G PP G       PPPPG  +GPPP G   P+
Sbjct: 92  SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQ 130



 Score = 57.0 bits (136), Expect = 1e-08
 Identities = 59/174 (33%), Positives = 64/174 (36%), Gaps = 19/174 (10%)

Query: 83  EGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVM 142
           +GPPP+     + P     G P      G   P G P P  P G   P +G    S Q  
Sbjct: 159 QGPPPQGGNQPQGP-PPPPGKPQGPPPQGGKKPQGPPPPGKPQG--PPPQGDKSRSSQSP 215

Query: 143 T--PQGRGTVAAAAAAATASIAGAPTQYPPGRG----GPPPPMGRGAPPPGMMGPPPGMR 196
              PQG                G P   PP  G    GPPPP     PP          R
Sbjct: 216 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSAR 275

Query: 197 PPMGPPMGIPPGRG-TPMGMPPP-GMRP-----PPPGM-RGP--PPPGMRPPRP 240
            P G P G P   G  P G PPP G  P     PP G  +GP  PP G RP RP
Sbjct: 276 SPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 329


>gi|154800441 proline-rich protein HaeIII subfamily 1 [Homo sapiens]
          Length = 166

 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 48/128 (37%), Positives = 58/128 (45%), Gaps = 25/128 (19%)

Query: 135 GGPSQQVMTPQGRGTVAAAAAAATASIAG----APTQYPPGRGG-----PPPPMGRGAPP 185
           GG S+Q +  + +G       +  ++  G     P Q PP +GG     PPPP G+   P
Sbjct: 35  GGDSEQFLDEERQGPPLGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGP 94

Query: 186 PGMMGPPPGMRPPMGPPMGIP-------PGRGTPMGMPPPGMR-----PPPPGM-RGPPP 232
           P   G PP   PP G P G P       P RG P G P  G       PPPPG  +GPPP
Sbjct: 95  PQQGGHPP---PPQGRPQGPPQQGGHPRPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPP 151

Query: 233 PGMRPPRP 240
            G RP  P
Sbjct: 152 QGGRPQGP 159



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 37/125 (29%), Positives = 39/125 (31%), Gaps = 41/125 (32%)

Query: 83  EGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVM 142
           +GPPP        P  G    P  GR  G     G P P  P G                
Sbjct: 82  QGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRP--PRG---------------- 123

Query: 143 TPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPP 202
            PQG                  P Q    + GPPPP     PP    GPPP    P GPP
Sbjct: 124 RPQG------------------PPQQGGHQQGPPPP-----PPGKPQGPPPQGGRPQGPP 160

Query: 203 MGIPP 207
            G  P
Sbjct: 161 QGQSP 165


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 49/134 (36%), Positives = 55/134 (41%), Gaps = 10/134 (7%)

Query: 112 RGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYP-P 170
           RG     P P+AP G          P      P      AAA A A  + A A T  P P
Sbjct: 104 RGATPPAP-PRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSP 162

Query: 171 GRGGPPPPMGRGAP---PPGMMGPPPGMRPPMGPPMGIPP---GRGTPMGMPPPGMRPPP 224
           G   P P   R AP   PP     PP + PP GP    PP    R  P  +PPP   P P
Sbjct: 163 GPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPP--LPPPPQPPAP 220

Query: 225 PGMRGPPPPGMRPP 238
           P  + PPPP  +PP
Sbjct: 221 PQQQQPPPPQPQPP 234



 Score = 33.1 bits (74), Expect = 0.22
 Identities = 36/120 (30%), Positives = 40/120 (33%), Gaps = 13/120 (10%)

Query: 85  PPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAP-----AGLAGPVRGVGGPSQ 139
           PPP     A V  A  A  P    AA    P+  P    P     A LA P      P  
Sbjct: 135 PPP-----APVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPA 189

Query: 140 QVMTPQGRGTVAAAAAAATASIAGAPTQ--YPPGRGGPPPPMGRGAPPPGMMGPPPGMRP 197
            V  P G       A AA       P Q   PP +  PPPP  +  P  G +      RP
Sbjct: 190 -VAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARP 248



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 28/96 (29%), Positives = 28/96 (29%), Gaps = 33/96 (34%)

Query: 160 SIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPG 219
           S   A    PP RG  PP     APP          R P G P         P   PPP 
Sbjct: 92  SYRNAARVQPPRRGATPP-----APP----------RAPRGAPAAAAAAAPPPTPAPPP- 135

Query: 220 MRPPPP---------------GMRGPPPPGMRPPRP 240
             PP P                   PP PG   P P
Sbjct: 136 --PPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGP 169



 Score = 28.5 bits (62), Expect = 5.4
 Identities = 21/81 (25%), Positives = 29/81 (35%), Gaps = 22/81 (27%)

Query: 129 GPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGM 188
           GP  G G  ++QV +          A+ AT   + +P   PPG+                
Sbjct: 394 GPAPGSG--TRQVFSMAAMNKEGGTASVATGPDSPSPVPLPPGK---------------- 435

Query: 189 MGPPPGMRPPMGPPMGIPPGR 209
               P +    G P G PPGR
Sbjct: 436 ----PALPGADGTPFGCPPGR 452


>gi|158966674 proline-rich protein HaeIII subfamily 2 [Homo sapiens]
          Length = 166

 Score = 70.1 bits (170), Expect = 2e-12
 Identities = 48/128 (37%), Positives = 58/128 (45%), Gaps = 25/128 (19%)

Query: 135 GGPSQQVMTPQGRGTVAAAAAAATASIAG----APTQYPPGRGG-----PPPPMGRGAPP 185
           GG S+Q +  + +G       +  ++  G     P Q PP +GG     PPPP G+   P
Sbjct: 35  GGDSEQFIDEERQGPPLGGQQSQPSAGDGNQNDGPQQGPPQQGGQQQQGPPPPQGKPQGP 94

Query: 186 PGMMGPPPGMRPPMGPPMGIP-------PGRGTPMGMPPPGMR-----PPPPGM-RGPPP 232
           P   G PP   PP G P G P       P RG P G P  G       PPPPG  +GPPP
Sbjct: 95  PQQGGHPP---PPQGRPQGPPQQGGHPRPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPP 151

Query: 233 PGMRPPRP 240
            G RP  P
Sbjct: 152 QGGRPQGP 159



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 37/125 (29%), Positives = 39/125 (31%), Gaps = 41/125 (32%)

Query: 83  EGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVM 142
           +GPPP        P  G    P  GR  G     G P P  P G                
Sbjct: 82  QGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRP--PRG---------------- 123

Query: 143 TPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPP 202
            PQG                  P Q    + GPPPP     PP    GPPP    P GPP
Sbjct: 124 RPQG------------------PPQQGGHQQGPPPP-----PPGKPQGPPPQGGRPQGPP 160

Query: 203 MGIPP 207
            G  P
Sbjct: 161 QGQSP 165


>gi|4826944 proline-rich protein HaeIII subfamily 2 [Homo sapiens]
          Length = 166

 Score = 70.1 bits (170), Expect = 2e-12
 Identities = 48/128 (37%), Positives = 58/128 (45%), Gaps = 25/128 (19%)

Query: 135 GGPSQQVMTPQGRGTVAAAAAAATASIAG----APTQYPPGRGG-----PPPPMGRGAPP 185
           GG S+Q +  + +G       +  ++  G     P Q PP +GG     PPPP G+   P
Sbjct: 35  GGDSEQFIDEERQGPPLGGQQSQPSAGDGNQNDGPQQGPPQQGGQQQQGPPPPQGKPQGP 94

Query: 186 PGMMGPPPGMRPPMGPPMGIP-------PGRGTPMGMPPPGMR-----PPPPGM-RGPPP 232
           P   G PP   PP G P G P       P RG P G P  G       PPPPG  +GPPP
Sbjct: 95  PQQGGHPP---PPQGRPQGPPQQGGHPRPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPP 151

Query: 233 PGMRPPRP 240
            G RP  P
Sbjct: 152 QGGRPQGP 159



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 37/125 (29%), Positives = 39/125 (31%), Gaps = 41/125 (32%)

Query: 83  EGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVM 142
           +GPPP        P  G    P  GR  G     G P P  P G                
Sbjct: 82  QGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRP--PRG---------------- 123

Query: 143 TPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPP 202
            PQG                  P Q    + GPPPP     PP    GPPP    P GPP
Sbjct: 124 RPQG------------------PPQQGGHQQGPPPP-----PPGKPQGPPPQGGRPQGPP 160

Query: 203 MGIPP 207
            G  P
Sbjct: 161 QGQSP 165


>gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]
          Length = 548

 Score = 69.7 bits (169), Expect = 2e-12
 Identities = 64/214 (29%), Positives = 83/214 (38%), Gaps = 22/214 (10%)

Query: 41  ILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPP-PKDTGIARVPLAG 99
           I  DC   R   P++++   R +K  L L+   GE  V  +V     P  T +A  P   
Sbjct: 288 IASDCKFQRPGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPA 347

Query: 100 AAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGV--GGPSQQVMTPQGRGTVAAAAAAA 157
           A        +      +  P   +    + P  G+  GGP      P    +      + 
Sbjct: 348 APANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPH---SFPHPLPSL 404

Query: 158 TASIAGAPTQY------PPGRGGPPPPMGRGAPPPGMMGPPP-----GMRPPMGPPMGIP 206
           T    G P Q+      PP    PPPPM +G  PPG  GPPP     G  P       + 
Sbjct: 405 TGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLH 464

Query: 207 PGRGTPMGMPPPGMRPPPPGMRGPPPPGMRPPRP 240
            G+G  M  PP GM PPPP    PPP G  PP P
Sbjct: 465 QGKGM-MPPPPMGMMPPPP----PPPSGQPPPPP 493


>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
          Length = 638

 Score = 69.7 bits (169), Expect = 2e-12
 Identities = 64/214 (29%), Positives = 83/214 (38%), Gaps = 22/214 (10%)

Query: 41  ILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPP-PKDTGIARVPLAG 99
           I  DC   R   P++++   R +K  L L+   GE  V  +V     P  T +A  P   
Sbjct: 288 IASDCKFQRPGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPA 347

Query: 100 AAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGV--GGPSQQVMTPQGRGTVAAAAAAA 157
           A        +      +  P   +    + P  G+  GGP      P    +      + 
Sbjct: 348 APANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPH---SFPHPLPSL 404

Query: 158 TASIAGAPTQY------PPGRGGPPPPMGRGAPPPGMMGPPP-----GMRPPMGPPMGIP 206
           T    G P Q+      PP    PPPPM +G  PPG  GPPP     G  P       + 
Sbjct: 405 TGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLH 464

Query: 207 PGRGTPMGMPPPGMRPPPPGMRGPPPPGMRPPRP 240
            G+G  M  PP GM PPPP    PPP G  PP P
Sbjct: 465 QGKGM-MPPPPMGMMPPPP----PPPSGQPPPPP 493



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 51/186 (27%), Positives = 65/186 (34%), Gaps = 42/186 (22%)

Query: 84  GPPPKDTGIARVPLAGAAGGPGIGRA-AGRGI----PAGVPMPQAPAGLAGPVRGVGGP- 137
           GPPP D  +   P+     G G+ R   G+G+    P G+  P  P     P     GP 
Sbjct: 443 GPPPMDQYLGSTPV-----GSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPL 497

Query: 138 --------------------SQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPP 177
                               +     P  + T     +A T SI     Q       P  
Sbjct: 498 PPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGA 557

Query: 178 PMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPP---GMRPPPPGMRGPPPPG 234
           P  +G P   M+  PPG++P       +PPG   P   PPP   GM  PP G  GP    
Sbjct: 558 PQMQGNPT--MVPLPPGVQP------PLPPGAPPPPPPPPPGSAGMMIPPRGGDGPSHES 609

Query: 235 MRPPRP 240
              PRP
Sbjct: 610 EDFPRP 615



 Score = 47.8 bits (112), Expect = 9e-06
 Identities = 60/230 (26%), Positives = 78/230 (33%), Gaps = 65/230 (28%)

Query: 76  NLVSMTVEGPP-----PKDTGIARVPLAGAAGGPGIG-RAAGRGIPA------GVPMPQA 123
           +L+S T   PP     P ++        G  GGPG G  +    +P+      G PM   
Sbjct: 357 SLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHN 416

Query: 124 PAGLAGP-VRGVGGPSQQVMTPQGR-GTVAAAAAAATASIAGAPTQYPPGRGG-PPPPMG 180
           P G   P ++    P  Q   P G  G         +  +     +   G+G  PPPPMG
Sbjct: 417 PNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMG 476

Query: 181 RGAPPP----GMMGPPPG----------MRPPMGPPMGIPPGRGTPM------------- 213
              PPP    G   PPP            +PP  PP        TP+             
Sbjct: 477 MMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSA 536

Query: 214 ---GMPP--------------------PGMRPPPPGMRGPPPPGMRPPRP 240
               +PP                    P M P PPG++ P PPG  PP P
Sbjct: 537 GTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPP 586


>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 69.7 bits (169), Expect = 2e-12
 Identities = 64/214 (29%), Positives = 83/214 (38%), Gaps = 22/214 (10%)

Query: 41  ILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPP-PKDTGIARVPLAG 99
           I  DC   R   P++++   R +K  L L+   GE  V  +V     P  T +A  P   
Sbjct: 288 IASDCKFQRPGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPA 347

Query: 100 AAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGV--GGPSQQVMTPQGRGTVAAAAAAA 157
           A        +      +  P   +    + P  G+  GGP      P    +      + 
Sbjct: 348 APANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPH---SFPHPLPSL 404

Query: 158 TASIAGAPTQY------PPGRGGPPPPMGRGAPPPGMMGPPP-----GMRPPMGPPMGIP 206
           T    G P Q+      PP    PPPPM +G  PPG  GPPP     G  P       + 
Sbjct: 405 TGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLH 464

Query: 207 PGRGTPMGMPPPGMRPPPPGMRGPPPPGMRPPRP 240
            G+G  M  PP GM PPPP    PPP G  PP P
Sbjct: 465 QGKGM-MPPPPMGMMPPPP----PPPSGQPPPPP 493



 Score = 57.0 bits (136), Expect = 1e-08
 Identities = 62/204 (30%), Positives = 73/204 (35%), Gaps = 63/204 (30%)

Query: 84  GPPPKDTGIARVPLAGAAGGPGIGRA-AGRGI----PAGVPMPQAPAGLAGPVRGVGGP- 137
           GPPP D  +   P+     G G+ R   G+G+    P G+  P  P     P     GP 
Sbjct: 443 GPPPMDQYLGSTPV-----GSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPL 497

Query: 138 ----SQQVMTPQ---------------------------GRGTV--------AAAAAAAT 158
                QQ   P                            G G++        AAAA+   
Sbjct: 498 PPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGA 557

Query: 159 ASIAGAPTQYPPGRGGPPP-PMGRGAPPP-------GMM-GPPPGMRPPMGPPMGIPPGR 209
             + G PT  P   G  PP P G   PPP       GMM  PPP   PPM P   +    
Sbjct: 558 PQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMG 617

Query: 210 GTPMGMPPPGMRPPPPGMRGPPPP 233
               GMPP GM P PP    PPPP
Sbjct: 618 MGVAGMPPFGMPPAPP----PPPP 637



 Score = 47.8 bits (112), Expect = 9e-06
 Identities = 60/230 (26%), Positives = 78/230 (33%), Gaps = 65/230 (28%)

Query: 76  NLVSMTVEGPP-----PKDTGIARVPLAGAAGGPGIG-RAAGRGIPA------GVPMPQA 123
           +L+S T   PP     P ++        G  GGPG G  +    +P+      G PM   
Sbjct: 357 SLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHN 416

Query: 124 PAGLAGP-VRGVGGPSQQVMTPQGR-GTVAAAAAAATASIAGAPTQYPPGRGG-PPPPMG 180
           P G   P ++    P  Q   P G  G         +  +     +   G+G  PPPPMG
Sbjct: 417 PNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMG 476

Query: 181 RGAPPP----GMMGPPPG----------MRPPMGPPMGIPPGRGTPM------------- 213
              PPP    G   PPP            +PP  PP        TP+             
Sbjct: 477 MMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSA 536

Query: 214 ---GMPP--------------------PGMRPPPPGMRGPPPPGMRPPRP 240
               +PP                    P M P PPG++ P PPG  PP P
Sbjct: 537 GTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPP 586


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 69.3 bits (168), Expect = 3e-12
 Identities = 55/165 (33%), Positives = 61/165 (36%), Gaps = 25/165 (15%)

Query: 85  PPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTP 144
           PPP+D+    V   G    PG+G A     PA    P A    +G   G           
Sbjct: 101 PPPQDSS-KPVVAQGPGPAPGVGSAP----PASSSAPPATPPTSGAPPG----------- 144

Query: 145 QGRGTVAAAAAAATASIAGAPTQYPPGRGGP-PPPMGRGAPPPGMMGPPPGMRPPMGPPM 203
            G G       A T++  GAP   PP  G P  PP   G PPP    P PG  P  GP  
Sbjct: 145 SGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGP 204

Query: 204 GIPPGRGTPMGMPP--------PGMRPPPPGMRGPPPPGMRPPRP 240
           G P G   P G  P        PG  P PP   G  P G R   P
Sbjct: 205 GGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHP 249



 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 34/88 (38%), Positives = 38/88 (43%), Gaps = 20/88 (22%)

Query: 171 GRGG------PPPPMG----RG--APPPGMMGPPPGMRPP------MGPPMGIPPGRGTP 212
           GRGG      PPP MG    RG   P PG  GP P + PP        PP   PP +  P
Sbjct: 24  GRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPP 83

Query: 213 MGMPPPGMRPPPPGMRGPPPPGMRPPRP 240
              PPP   P P   + PPPP     +P
Sbjct: 84  PHQPPP--HPQPHQQQQPPPPPQDSSKP 109



 Score = 48.1 bits (113), Expect = 7e-06
 Identities = 50/169 (29%), Positives = 57/169 (33%), Gaps = 42/169 (24%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAAT 158
           G  GG G G    R  P G+ + Q   G  GP  G  GP   +  P              
Sbjct: 20  GGGGGRG-GLHDFRSPPPGMGLNQN-RGPMGPGPGQSGPKPPIPPPPPHQQQQQP----- 72

Query: 159 ASIAGAPTQYPPGRGGPP--------PPMGRGAPPPGM----------MGPPPGM----- 195
                 P Q PP +  PP        P   +  PPP             GP PG+     
Sbjct: 73  ------PPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPP 126

Query: 196 ----RPPMGPP-MGIPPGRGT-PMGMPPPGMRPPPPGMRGPPPPGMRPP 238
                PP  PP  G PPG G  P   PPP +   PPG   P PP    P
Sbjct: 127 ASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVP 175



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 25/71 (35%), Positives = 29/71 (40%), Gaps = 4/71 (5%)

Query: 170 PGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
           PG+ GP PP+    P      PPP   PP  PP   PP    P   P    +PPPP    
Sbjct: 51  PGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPP----PHPQPHQQQQPPPPPQDS 106

Query: 230 PPPPGMRPPRP 240
             P   + P P
Sbjct: 107 SKPVVAQGPGP 117



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 40/120 (33%), Positives = 43/120 (35%), Gaps = 32/120 (26%)

Query: 79  SMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPS 138
           S  V   PP+  G    P A    GPG  +  G G P G  MP       GP  G GGP 
Sbjct: 171 SSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMP------GGPKPG-GGPG 223

Query: 139 QQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPP----GMMGPPPG 194
             + TP G                      PP RGG  P  GR   PP       GPPPG
Sbjct: 224 --LSTPGGH-------------------PKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPG 262



 Score = 32.0 bits (71), Expect = 0.49
 Identities = 28/78 (35%), Positives = 32/78 (41%), Gaps = 20/78 (25%)

Query: 171 GRGGPPPPMGRGAPPPGM---MGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGM 227
           G GG     G G    G+     PPPGM        G+   RG PMG P PG   P P +
Sbjct: 11  GGGGGFHRRGGGGGRGGLHDFRSPPPGM--------GLNQNRG-PMG-PGPGQSGPKPPI 60

Query: 228 RGPP-------PPGMRPP 238
             PP       PP  +PP
Sbjct: 61  PPPPPHQQQQQPPPQQPP 78


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 69.3 bits (168), Expect = 3e-12
 Identities = 56/159 (35%), Positives = 63/159 (39%), Gaps = 10/159 (6%)

Query: 83  EGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVM 142
           +GPPP+       P  G  G    G     G P G P PQ      GP    G P     
Sbjct: 153 QGPPPRPGKPEGPPPQG--GNQSQGPPPHPGKPEGPP-PQGGNQSQGPPPRPGKPEGP-- 207

Query: 143 TPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPP 202
            PQG G  +           G P+Q      GPPP  G+   PP   G  P   PP G P
Sbjct: 208 PPQG-GNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRP 266

Query: 203 MGIPPGRGTP-MGMPPPGMRPPPPGMRGPPPPGMRPPRP 240
            G PP  G P   +PPP  +P  P    PPP G RP RP
Sbjct: 267 QGPPPPGGNPQQPLPPPAGKPQGP---PPPPQGGRPHRP 302



 Score = 62.4 bits (150), Expect = 3e-10
 Identities = 60/175 (34%), Positives = 65/175 (37%), Gaps = 24/175 (13%)

Query: 83  EGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVM 142
           +GPPP+       P  G  G    G     G P G P PQ      GP    G P     
Sbjct: 69  QGPPPRPGKPEGPPPQG--GNQSQGPPPRPGKPEGQP-PQGGNQSQGPPPRPGKPEGP-- 123

Query: 143 TPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGR--GAPPPG---MMGPPPGMRP 197
            PQG G  +           G P Q      GPPP  G+  G PP G     GPPP    
Sbjct: 124 PPQG-GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGK 182

Query: 198 PMGPP-------MGIPPGRGTPMGMPPPGMR-----PPPPGM-RGPPPPGMRPPR 239
           P GPP        G PP  G P G PP G       PP PG   GPP  G   P+
Sbjct: 183 PEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQ 237



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 45/111 (40%), Positives = 47/111 (42%), Gaps = 22/111 (19%)

Query: 144 PQGRGTVAAAAAAATASIAGAPTQYPPGRG----GPPPPMGR--GAPPPG---MMGPPPG 194
           P+GR          T    G P   PP  G    GPPP  G+  G PP G     GPPP 
Sbjct: 36  PEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPP- 94

Query: 195 MRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPPGMR-----PPRP 240
            RP  G P G PP  G     PPP  RP  P   GPPP G       PPRP
Sbjct: 95  -RP--GKPEGQPPQGGNQSQGPPP--RPGKP--EGPPPQGGNQSQGPPPRP 138



 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 57/173 (32%), Positives = 62/173 (35%), Gaps = 37/173 (21%)

Query: 101 AGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRG--VGGPSQQVMTPQGRGTVAAAAAAAT 158
           +G P   R  G   P   P P        P  G    GP  +   P+G        +   
Sbjct: 33  SGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGP 92

Query: 159 ASIAGAPTQYPPGRG----GPPPPMGR--GAPPPG---MMGPPPGMRPPMGPP------- 202
               G P   PP  G    GPPP  G+  G PP G     GPPP  RP  G P       
Sbjct: 93  PPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPP--RP--GKPEGPPPQG 148

Query: 203 ----MGIPPGRGTPMGMPPPGMR-----PPPPGM-RGPPPPGMR-----PPRP 240
                G PP  G P G PP G       PP PG   GPPP G       PPRP
Sbjct: 149 GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRP 201



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 37/93 (39%), Positives = 38/93 (40%), Gaps = 20/93 (21%)

Query: 161 IAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMG--PPMGIPPGRGTPMGMPPP 218
           I+G P    P  G  P    R  PPPG     P  RPP G     G PP  G P G PP 
Sbjct: 32  ISGKPEGRRPQGGNQPQ---RTPPPPGK----PEGRPPQGGNQSQGPPPRPGKPEGPPPQ 84

Query: 219 GMR-----PPPPGM-RGPPPPGMR-----PPRP 240
           G       PP PG   G PP G       PPRP
Sbjct: 85  GGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRP 117


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 68.9 bits (167), Expect = 4e-12
 Identities = 55/162 (33%), Positives = 68/162 (41%), Gaps = 38/162 (23%)

Query: 76  NLVSMTVEGPPP--KDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRG 133
           N+ S++   PP   KD   A  P+ G A      + A    PA +P P            
Sbjct: 611 NISSLSQLSPPNDHKDIHAALQPMEGMASNQ---QKALPPPPASIPPPPP---------- 657

Query: 134 VGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPP 193
                     P G G+++ A      S AG P   PP    PPPP+    PPP   GPPP
Sbjct: 658 ---------LPSGLGSLSPAPPMPPVS-AGPPLPPPPP---PPPPL----PPPSSAGPPP 700

Query: 194 GMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPPGM 235
              PP  PP+   P    P G PP    PPPPG+  PPPPG+
Sbjct: 701 ---PPPPPPLPNSPAPPNPGGPPPA---PPPPGLAPPPPPGL 736



 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 32/76 (42%), Positives = 35/76 (46%), Gaps = 4/76 (5%)

Query: 169 PPGRGGPPPPM--GRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTP--MGMPPPGMRPPP 224
           PP    PPPP+  G G+  P    PP    PP+ PP   PP    P   G PPP   PP 
Sbjct: 648 PPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPL 707

Query: 225 PGMRGPPPPGMRPPRP 240
           P    PP PG  PP P
Sbjct: 708 PNSPAPPNPGGPPPAP 723



 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 28/63 (44%), Positives = 32/63 (50%), Gaps = 7/63 (11%)

Query: 184 PPPGMMGPPPGMRPPMG-----PPMGIPPGRGTPMGMPPPGMRP-PPPGMRGPPPPGMRP 237
           PPP  + PPP +   +G     PPM  P   G P+  PPP   P PPP   GPPPP   P
Sbjct: 647 PPPASIPPPPPLPSGLGSLSPAPPMP-PVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPP 705

Query: 238 PRP 240
           P P
Sbjct: 706 PLP 708


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score = 68.9 bits (167), Expect = 4e-12
 Identities = 61/196 (31%), Positives = 69/196 (35%), Gaps = 43/196 (21%)

Query: 84   GPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGP--VRGVGGPSQQV 141
            GPP  D         G AG  G   A G   P+G P PQ P G+ GP   RG  GP    
Sbjct: 837  GPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGAT 896

Query: 142  MTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPP-----PGMMGP----- 191
              P   G V    +       G P   P G+ GP    G   PP     PG+ GP     
Sbjct: 897  GFPGAAGRVGPPGSNGNPGPPGPPG--PSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPG 954

Query: 192  ---------PPGMRPPMGPP--------MGIP--------PGRGTPMGMPPPGMRPPPPG 226
                     P G   P GP         +G+P        PG   P G P     P   G
Sbjct: 955  EKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASG 1014

Query: 227  MRGPP----PPGMRPP 238
             RGPP    PPG+  P
Sbjct: 1015 DRGPPGPVGPPGLTGP 1030



 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 61/182 (33%), Positives = 72/182 (39%), Gaps = 35/182 (19%)

Query: 83   EGPPPKD-----------TGIARVPLA-GAAGGPG----IGRAAGRGIPAGVPMPQAPAG 126
            +GPP +D           TG    P A G  G PG     G+   RG  AG   P  P+G
Sbjct: 1043 DGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRG-EAGAQGPMGPSG 1101

Query: 127  LAGPVRGVGGPSQ------QVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG 180
             AG  RG+ GP        +   P  RG            + G P   P G  G   P G
Sbjct: 1102 PAG-ARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPG--PSGDQGASGPAG 1158

Query: 181  RGAP--PPGMMGPPP-----GMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPP 233
               P  PPG +GP       G+  P+GPP   P GR    G   P   P PPG  GPP P
Sbjct: 1159 PSGPRGPPGPVGPSGKDGANGIPGPIGPPG--PRGRSGETGPAGPPGNPGPPGPPGPPGP 1216

Query: 234  GM 235
            G+
Sbjct: 1217 GI 1218



 Score = 59.7 bits (143), Expect = 2e-09
 Identities = 59/188 (31%), Positives = 66/188 (35%), Gaps = 38/188 (20%)

Query: 83  EGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVM 142
           +GPP           AG AG  G     G   P G P      GL GP+    GP     
Sbjct: 743 QGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPI----GPPGPAG 798

Query: 143 TPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPP----------------- 185
               +G V     A +A   GAP +   G  GPP P G   PP                 
Sbjct: 799 ANGEKGEVGPPGPAGSAGARGAPGE--RGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQ 856

Query: 186 ------PGMMGP--PPGMRPPMG--PPMGIPPGRGTP--MGMPPPGMRPPPPGMRG-PPP 232
                 PG  GP   PG + P G   P G    +G P   G P    R  PPG  G P P
Sbjct: 857 KGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGP 916

Query: 233 PGMRPPRP 240
           PG  PP P
Sbjct: 917 PG--PPGP 922



 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 66/187 (35%), Positives = 72/187 (38%), Gaps = 43/187 (22%)

Query: 83  EGPPPKDTGIARVPLAGAAGGPG----------------IGRAAGRGIPA--GVPMPQAP 124
           EG P KD G     L G  G PG                 G A  RG P   G   P  P
Sbjct: 776 EGAPGKDGGRG---LTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP 832

Query: 125 AGLAGPVRGVGGPSQQVMTPQGR-GTVAAAAAAATASIAGAP-TQYPPGRGGPPPPMGRG 182
           AG AGP    G P  +    QG  G    A A      +GAP  Q P G  GP    G  
Sbjct: 833 AGFAGPPGADGQPGAK--GEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQ 890

Query: 183 APP--------PGMMGPP--PGMRPPMGPPMGIPPGRGTPMG----MPPPGMRPPPPGMR 228
            PP         G +GPP   G   P GPP   P G+  P G      PPG R   PG++
Sbjct: 891 GPPGATGFPGAAGRVGPPGSNGNPGPPGPPG--PSGKDGPKGARGDSGPPG-RAGEPGLQ 947

Query: 229 GPP-PPG 234
           GP  PPG
Sbjct: 948 GPAGPPG 954



 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 51/158 (32%), Positives = 55/158 (34%), Gaps = 13/158 (8%)

Query: 84  GPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMT 143
           GPP        +   G  G PGI    G   P G P P  P G  GP  G  G       
Sbjct: 438 GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA-GEEGKRGARGE 496

Query: 144 PQGRGTVAAAAAAATASIAGAPTQ----YPPGRGGPPPPMGRGAP-----PPGMMGPP-- 192
           P G G +            G P Q     P G  G   P G   P      PG  G P  
Sbjct: 497 PGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGL 556

Query: 193 PGMRPPMGPPMGI-PPGRGTPMGMPPPGMRPPPPGMRG 229
           PG R   G P    P G+  P G P    RP PPG +G
Sbjct: 557 PGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQG 594



 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 56/156 (35%), Positives = 62/156 (39%), Gaps = 16/156 (10%)

Query: 84   GPPPKDTGIARVP-LAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVM 142
            GPP    G A  P L G AG PG     G   P+G   P  P GLAG    VG P Q+  
Sbjct: 936  GPP----GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQR-- 989

Query: 143  TPQGRGTVAAAAAAATASIAGAP----TQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPP 198
                RG       +      GAP     + PPG  GPP   G  A  PG  G P    PP
Sbjct: 990  --GERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTG-PAGEPGREGSPGADGPP 1046

Query: 199  -MGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPP 233
                  G+   RG    +  PG  P PPG  GP  P
Sbjct: 1047 GRDGAAGVKGDRGETGAVGAPG-APGPPGSPGPAGP 1081



 Score = 54.3 bits (129), Expect = 9e-08
 Identities = 51/146 (34%), Positives = 57/146 (39%), Gaps = 14/146 (9%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAAT 158
           G AG PG+   +G     G P P  P GL G  RG  GP+         G    A     
Sbjct: 300 GEAGAPGVKGESGSPGENGSPGPMGPRGLPGE-RGRTGPAGAAGARGNDGQPGPAGPPGP 358

Query: 159 ASIAGAPTQYP--PGRGGPPPPMGRGAP-----PPGMMGPP--PGMRPPMGPP--MGIPP 207
              AG P  +P  PG  G   P G   P     P G  G P  PG     G P   GIP 
Sbjct: 359 VGPAGGP-GFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPG 417

Query: 208 GRGTPMGMPPPGMRPPPPGMRGPPPP 233
            +G+  G P     P  PG RGPP P
Sbjct: 418 AKGS-AGAPGIAGAPGFPGPRGPPGP 442



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 57/186 (30%), Positives = 61/186 (32%), Gaps = 50/186 (26%)

Query: 97  LAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVG--------------------- 135
           L G  G  G   AAG     G P P  P G  GP  G G                     
Sbjct: 328 LPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEG 387

Query: 136 --GPSQQVMTPQGRGTVAAA------------AAAATASIAGAPTQYPPGRGGPPPPMGR 181
             GP  +  TP   G   A+             +A    IAGAP    PG  GPP P G 
Sbjct: 388 AQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF--PGPRGPPGPQGA 445

Query: 182 GAP--PPGMMGPP--PGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPP------ 231
             P  P G  G P   G +   GP     PG   P G P P       G RG P      
Sbjct: 446 TGPLGPKGQTGEPGIAGFKGEQGPKG--EPGPAGPQGAPGPAGEEGKRGARGEPGGVGPI 503

Query: 232 -PPGMR 236
            PPG R
Sbjct: 504 GPPGER 509



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 55/173 (31%), Positives = 63/173 (36%), Gaps = 36/173 (20%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQ--QVMTPQGRGTVAA---A 153
           GA G  G     G   P G P  + P+GLAGP    G P +  +   P  RG       A
Sbjct: 510 GAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDA 569

Query: 154 AAAATASIAGAPTQYPPGRGGPPPPMG-RGAP-------PPGMMGPP-----------PG 194
                   +GAP +   GR GPP P G RG P       P G  G P           PG
Sbjct: 570 GPQGKVGPSGAPGE--DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPG 627

Query: 195 MRP---------PMGPPMGI-PPGRGTPMGMPPPGMRPPPPGMRGPPPPGMRP 237
           +R            GPP    P G     G P P      PG  GPP  G +P
Sbjct: 628 LRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKP 680



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 53/142 (37%), Positives = 57/142 (40%), Gaps = 18/142 (12%)

Query: 99  GAAGGPGI-GRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAA 157
           G  G PG  GR    G P G P P  P G  GP  G+GG        Q  G     A  A
Sbjct: 141 GEKGAPGPRGRDGEPGTP-GNPGPPGPPGPPGPP-GLGGN----FAAQMAGGFDEKAGGA 194

Query: 158 TASIAGAPTQYPPGRGGPPPPMGRGAP-PPGMMGPP-----PGMRPPMGPPMGIPPGRGT 211
              +   P   P G  GPP P G  AP P G  G P     PG+  PMGP    PPG   
Sbjct: 195 QLGVMQGPMG-PMGPRGPPGPAG--APGPQGFQGNPGEPGEPGVSGPMGPRG--PPGPPG 249

Query: 212 PMGMPPPGMRPPPPGMRGPPPP 233
             G      +P   G RGPP P
Sbjct: 250 KPGDDGEAGKPGKAGERGPPGP 271



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 52/156 (33%), Positives = 60/156 (38%), Gaps = 38/156 (24%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAAT 158
           G+AG PGI  A G   P G P PQ   G  GP    G P                     
Sbjct: 420 GSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEP--------------------- 458

Query: 159 ASIAGAPTQYPPGRGGPPPPMGRGAPPP-------GMMGPPPGMRPPMGPP--MGIPPGR 209
             IAG   +  P +G P P   +GAP P       G  G P G+  P+GPP   G P  R
Sbjct: 459 -GIAGFKGEQGP-KGEPGPAGPQGAPGPAGEEGKRGARGEPGGV-GPIGPPGERGAPGNR 515

Query: 210 GTP--MGMPPPGMRP---PPPGMRGPPPPGMRPPRP 240
           G P   G+  P   P    P G+ GP      P RP
Sbjct: 516 GFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRP 551



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 55/173 (31%), Positives = 61/173 (35%), Gaps = 38/173 (21%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGP--------------------VRGVGGPS 138
           GAAG PG    AG     G P P    GL GP                      G+ GP 
Sbjct: 639 GAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPR 698

Query: 139 QQVMTPQGRGTVAAAAAAATASIAGAP-TQYPPGRGGPPPPMGRGAPP-----PGMMGP- 191
            +   P  RG+  A        + G P T  P G  GP  P G   PP     PG  G  
Sbjct: 699 GERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAA 758

Query: 192 ----PPGMRPPMGP--PMGIP---PGRGT--PMGMPPPGMRPPPPGMRGPPPP 233
               P G R  +G   P G P    GRG   P+G P P       G  GPP P
Sbjct: 759 GIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGP 811



 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 54/172 (31%), Positives = 58/172 (33%), Gaps = 35/172 (20%)

Query: 92  IARVPLAGAAGGPGIGRAAGRGI-------PAGVPMPQAPAGLAGPVRGVGGPSQQVMTP 144
           I    LA A+G PG     G          P G P PQ PAG  GP RG  G   +   P
Sbjct: 88  ICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGP-RGDRGDKGEKGAP 146

Query: 145 QGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG----------------RGAPPPGM 188
             RG                    PPG  GPP P G                 G    G+
Sbjct: 147 GPRGRDGEPGTPGNPG--------PPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV 198

Query: 189 MGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPPGMRPPRP 240
           M  P G   P GPP   P G   P G       P  PG+ GP  P   PP P
Sbjct: 199 MQGPMGPMGPRGPPG--PAGAPGPQGFQGNPGEPGEPGVSGPMGP-RGPPGP 247



 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 48/147 (32%), Positives = 56/147 (38%), Gaps = 35/147 (23%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAAT 158
           G  G PG+    G+    G   P  PAG AG                 RG   A   +  
Sbjct: 621 GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGE----------------RGEQGAPGPSGF 664

Query: 159 ASIAGAPTQYPPGRGGPPPPMG--RGAPPPGMMGPP-----PGMRPPMGP-----PMGIP 206
             + G P   PPG GG P   G    A  PG++GP      PG R   G      P G+P
Sbjct: 665 QGLPGPPG--PPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP 722

Query: 207 PGRGTPMGMPPPGMRPP--PPGMRGPP 231
              GTP    P G   P  PPG +GPP
Sbjct: 723 ---GTPGTDGPKGASGPAGPPGAQGPP 746



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 50/163 (30%), Positives = 61/163 (37%), Gaps = 26/163 (15%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAAT 158
           G  G PG     G+  P+G P      G  GP +G  G    +  P  +G       A  
Sbjct: 561 GLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGP-QGARGQPGVMGFPGPKGANGEPGKAGE 619

Query: 159 ASIAGAP-------TQYPPGRGGPPPPMG-------RGAPPPGMMGPPPGMRPPMGPPM- 203
             + GAP            G  GPP P G       +GAP P      PG   P GPP  
Sbjct: 620 KGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPG---PPGPPGE 676

Query: 204 -GIPPGRGTPMGMPPPGMRPPP-----PGMRGPP-PPGMRPPR 239
            G P  +G P     PG+  P      PG RG P   G++ PR
Sbjct: 677 GGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPR 719



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 54/162 (33%), Positives = 61/162 (37%), Gaps = 20/162 (12%)

Query: 86  PPKDTGIARVPLAGA----AGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQ- 140
           PP   G     +AG     AGG  +G   G   P G   P  PAG  GP    G P +  
Sbjct: 172 PPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG 231

Query: 141 ---VMTPQG-RGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG-RGAP-PPGMMGPP-- 192
              V  P G RG             AG P +   G  GPP P G RG P  PG+ G    
Sbjct: 232 EPGVSGPMGPRGPPGPPGKPGDDGEAGKPGK--AGERGPPGPQGARGFPGTPGLPGVKGH 289

Query: 193 ---PGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPP 231
              PG+    G   G P  +G   G P     P P G RG P
Sbjct: 290 RGYPGLDGAKG-EAGAPGVKG-ESGSPGENGSPGPMGPRGLP 329



 Score = 41.2 bits (95), Expect = 8e-04
 Identities = 59/202 (29%), Positives = 65/202 (32%), Gaps = 52/202 (25%)

Query: 83   EGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGP----- 137
            EGPP       +  + G  G  G     G   P+G P  Q   G +G  RG  GP     
Sbjct: 968  EGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGD-RGPPGPVGPPG 1026

Query: 138  ------------SQQVMTPQGR-GTVAAAAAAATASIAGAP-TQYPPGRGGPPPPMGR-- 181
                        S     P GR G              GAP    PPG  GP  P G+  
Sbjct: 1027 LTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1086

Query: 182  ---GAPPPGMMGP--PPGMRPPMGP--PMGIPPGRGTP--------------MGMP-PPG 219
                A   G MGP  P G R   GP  P G     G P               G+P PPG
Sbjct: 1087 DRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPG 1146

Query: 220  MR--------PPPPGMRGPPPP 233
                        P G RGPP P
Sbjct: 1147 PSGDQGASGPAGPSGPRGPPGP 1168



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 34/107 (31%), Positives = 39/107 (36%), Gaps = 16/107 (14%)

Query: 97   LAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGP-----VRGVGGPSQQVMTPQGRGTVA 151
            L G  G PG     G   PAG   P+ P G  GP       G+ GP   +  P  RG   
Sbjct: 1138 LQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGP---IGPPGPRGR-- 1192

Query: 152  AAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPP 198
                +     AG P    PG  GPP P G G       G  P  + P
Sbjct: 1193 ----SGETGPAGPPGN--PGPPGPPGPPGPGIDMSAFAGLGPREKGP 1233



 Score = 37.0 bits (84), Expect = 0.015
 Identities = 50/159 (31%), Positives = 58/159 (36%), Gaps = 47/159 (29%)

Query: 82   VEGP--PPKDTGIARVP----LAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVG 135
            ++GP  P  D G A  P    L G  G  G+    G   P+G      PAG +GP RG  
Sbjct: 1108 IQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGP-RGPP 1166

Query: 136  GPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGA------PPPGMM 189
            GP    + P G+                      PG  GPP P GR        PP    
Sbjct: 1167 GP----VGPSGKDGANGI----------------PGPIGPPGPRGRSGETGPAGPPGNP- 1205

Query: 190  GPPPGMRPPMGPPMGIPPGRGTPM----GMPPPGMRPPP 224
            GPP       GPP   PPG G  M    G+ P    P P
Sbjct: 1206 GPP-------GPPG--PPGPGIDMSAFAGLGPREKGPDP 1235


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 68.9 bits (167), Expect = 4e-12
 Identities = 61/196 (31%), Positives = 69/196 (35%), Gaps = 43/196 (21%)

Query: 84  GPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGP--VRGVGGPSQQV 141
           GPP  D         G AG  G   A G   P+G P PQ P G+ GP   RG  GP    
Sbjct: 768 GPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGAT 827

Query: 142 MTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPP-----PGMMGP----- 191
             P   G V    +       G P   P G+ GP    G   PP     PG+ GP     
Sbjct: 828 GFPGAAGRVGPPGSNGNPGPPGPPG--PSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPG 885

Query: 192 ---------PPGMRPPMGPP--------MGIP--------PGRGTPMGMPPPGMRPPPPG 226
                    P G   P GP         +G+P        PG   P G P     P   G
Sbjct: 886 EKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASG 945

Query: 227 MRGPP----PPGMRPP 238
            RGPP    PPG+  P
Sbjct: 946 DRGPPGPVGPPGLTGP 961



 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 61/182 (33%), Positives = 72/182 (39%), Gaps = 35/182 (19%)

Query: 83   EGPPPKD-----------TGIARVPLA-GAAGGPG----IGRAAGRGIPAGVPMPQAPAG 126
            +GPP +D           TG    P A G  G PG     G+   RG  AG   P  P+G
Sbjct: 974  DGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRG-EAGAQGPMGPSG 1032

Query: 127  LAGPVRGVGGPSQ------QVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG 180
             AG  RG+ GP        +   P  RG            + G P   P G  G   P G
Sbjct: 1033 PAG-ARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPG--PSGDQGASGPAG 1089

Query: 181  RGAP--PPGMMGPPP-----GMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPP 233
               P  PPG +GP       G+  P+GPP   P GR    G   P   P PPG  GPP P
Sbjct: 1090 PSGPRGPPGPVGPSGKDGANGIPGPIGPPG--PRGRSGETGPAGPPGNPGPPGPPGPPGP 1147

Query: 234  GM 235
            G+
Sbjct: 1148 GI 1149



 Score = 59.7 bits (143), Expect = 2e-09
 Identities = 59/188 (31%), Positives = 66/188 (35%), Gaps = 38/188 (20%)

Query: 83  EGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVM 142
           +GPP           AG AG  G     G   P G P      GL GP+    GP     
Sbjct: 674 QGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPI----GPPGPAG 729

Query: 143 TPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPP----------------- 185
               +G V     A +A   GAP +   G  GPP P G   PP                 
Sbjct: 730 ANGEKGEVGPPGPAGSAGARGAPGE--RGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQ 787

Query: 186 ------PGMMGP--PPGMRPPMG--PPMGIPPGRGTP--MGMPPPGMRPPPPGMRG-PPP 232
                 PG  GP   PG + P G   P G    +G P   G P    R  PPG  G P P
Sbjct: 788 KGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGP 847

Query: 233 PGMRPPRP 240
           PG  PP P
Sbjct: 848 PG--PPGP 853



 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 66/187 (35%), Positives = 72/187 (38%), Gaps = 43/187 (22%)

Query: 83  EGPPPKDTGIARVPLAGAAGGPG----------------IGRAAGRGIPA--GVPMPQAP 124
           EG P KD G     L G  G PG                 G A  RG P   G   P  P
Sbjct: 707 EGAPGKDGGRG---LTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP 763

Query: 125 AGLAGPVRGVGGPSQQVMTPQGR-GTVAAAAAAATASIAGAP-TQYPPGRGGPPPPMGRG 182
           AG AGP    G P  +    QG  G    A A      +GAP  Q P G  GP    G  
Sbjct: 764 AGFAGPPGADGQPGAK--GEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQ 821

Query: 183 APP--------PGMMGPP--PGMRPPMGPPMGIPPGRGTPMG----MPPPGMRPPPPGMR 228
            PP         G +GPP   G   P GPP   P G+  P G      PPG R   PG++
Sbjct: 822 GPPGATGFPGAAGRVGPPGSNGNPGPPGPPG--PSGKDGPKGARGDSGPPG-RAGEPGLQ 878

Query: 229 GPP-PPG 234
           GP  PPG
Sbjct: 879 GPAGPPG 885



 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 51/158 (32%), Positives = 55/158 (34%), Gaps = 13/158 (8%)

Query: 84  GPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMT 143
           GPP        +   G  G PGI    G   P G P P  P G  GP  G  G       
Sbjct: 369 GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA-GEEGKRGARGE 427

Query: 144 PQGRGTVAAAAAAATASIAGAPTQ----YPPGRGGPPPPMGRGAP-----PPGMMGPP-- 192
           P G G +            G P Q     P G  G   P G   P      PG  G P  
Sbjct: 428 PGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGL 487

Query: 193 PGMRPPMGPPMGI-PPGRGTPMGMPPPGMRPPPPGMRG 229
           PG R   G P    P G+  P G P    RP PPG +G
Sbjct: 488 PGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQG 525



 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 56/156 (35%), Positives = 62/156 (39%), Gaps = 16/156 (10%)

Query: 84   GPPPKDTGIARVP-LAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVM 142
            GPP    G A  P L G AG PG     G   P+G   P  P GLAG    VG P Q+  
Sbjct: 867  GPP----GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQR-- 920

Query: 143  TPQGRGTVAAAAAAATASIAGAP----TQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPP 198
                RG       +      GAP     + PPG  GPP   G  A  PG  G P    PP
Sbjct: 921  --GERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTG-PAGEPGREGSPGADGPP 977

Query: 199  -MGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPP 233
                  G+   RG    +  PG  P PPG  GP  P
Sbjct: 978  GRDGAAGVKGDRGETGAVGAPG-APGPPGSPGPAGP 1012



 Score = 54.3 bits (129), Expect = 9e-08
 Identities = 51/146 (34%), Positives = 57/146 (39%), Gaps = 14/146 (9%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAAT 158
           G AG PG+   +G     G P P  P GL G  RG  GP+         G    A     
Sbjct: 231 GEAGAPGVKGESGSPGENGSPGPMGPRGLPGE-RGRTGPAGAAGARGNDGQPGPAGPPGP 289

Query: 159 ASIAGAPTQYP--PGRGGPPPPMGRGAP-----PPGMMGPP--PGMRPPMGPP--MGIPP 207
              AG P  +P  PG  G   P G   P     P G  G P  PG     G P   GIP 
Sbjct: 290 VGPAGGP-GFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPG 348

Query: 208 GRGTPMGMPPPGMRPPPPGMRGPPPP 233
            +G+  G P     P  PG RGPP P
Sbjct: 349 AKGS-AGAPGIAGAPGFPGPRGPPGP 373



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 57/186 (30%), Positives = 61/186 (32%), Gaps = 50/186 (26%)

Query: 97  LAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVG--------------------- 135
           L G  G  G   AAG     G P P  P G  GP  G G                     
Sbjct: 259 LPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEG 318

Query: 136 --GPSQQVMTPQGRGTVAAA------------AAAATASIAGAPTQYPPGRGGPPPPMGR 181
             GP  +  TP   G   A+             +A    IAGAP    PG  GPP P G 
Sbjct: 319 AQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF--PGPRGPPGPQGA 376

Query: 182 GAP--PPGMMGPP--PGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPP------ 231
             P  P G  G P   G +   GP     PG   P G P P       G RG P      
Sbjct: 377 TGPLGPKGQTGEPGIAGFKGEQGPKG--EPGPAGPQGAPGPAGEEGKRGARGEPGGVGPI 434

Query: 232 -PPGMR 236
            PPG R
Sbjct: 435 GPPGER 440



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 55/173 (31%), Positives = 63/173 (36%), Gaps = 36/173 (20%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQ--QVMTPQGRGTVAA---A 153
           GA G  G     G   P G P  + P+GLAGP    G P +  +   P  RG       A
Sbjct: 441 GAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDA 500

Query: 154 AAAATASIAGAPTQYPPGRGGPPPPMG-RGAP-------PPGMMGPP-----------PG 194
                   +GAP +   GR GPP P G RG P       P G  G P           PG
Sbjct: 501 GPQGKVGPSGAPGE--DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPG 558

Query: 195 MRP---------PMGPPMGI-PPGRGTPMGMPPPGMRPPPPGMRGPPPPGMRP 237
           +R            GPP    P G     G P P      PG  GPP  G +P
Sbjct: 559 LRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKP 611



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 52/156 (33%), Positives = 60/156 (38%), Gaps = 38/156 (24%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAAT 158
           G+AG PGI  A G   P G P PQ   G  GP    G P                     
Sbjct: 351 GSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEP--------------------- 389

Query: 159 ASIAGAPTQYPPGRGGPPPPMGRGAPPP-------GMMGPPPGMRPPMGPP--MGIPPGR 209
             IAG   +  P +G P P   +GAP P       G  G P G+  P+GPP   G P  R
Sbjct: 390 -GIAGFKGEQGP-KGEPGPAGPQGAPGPAGEEGKRGARGEPGGV-GPIGPPGERGAPGNR 446

Query: 210 GTP--MGMPPPGMRP---PPPGMRGPPPPGMRPPRP 240
           G P   G+  P   P    P G+ GP      P RP
Sbjct: 447 GFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRP 482



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 61/184 (33%), Positives = 69/184 (37%), Gaps = 32/184 (17%)

Query: 82  VEGPPPKD--TGIARVP-LAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGP-------- 130
           + G P KD  TG A  P  AG AG  G   A G     G+P P  P G  G         
Sbjct: 559 LRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPG 618

Query: 131 ---VRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAP-TQYPPGRGGPPPPMGRGAPP- 185
                G+ GP  +   P  RG+  A        + G P T  P G  GP  P G   PP 
Sbjct: 619 EAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPG 678

Query: 186 ----PGMMGP-----PPGMRPPMGP--PMGIP---PGRGT--PMGMPPPGMRPPPPGMRG 229
               PG  G      P G R  +G   P G P    GRG   P+G P P       G  G
Sbjct: 679 LQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVG 738

Query: 230 PPPP 233
           PP P
Sbjct: 739 PPGP 742



 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 48/147 (32%), Positives = 56/147 (38%), Gaps = 35/147 (23%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAAT 158
           G  G PG+    G+    G   P  PAG AG                 RG   A   +  
Sbjct: 552 GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGE----------------RGEQGAPGPSGF 595

Query: 159 ASIAGAPTQYPPGRGGPPPPMG--RGAPPPGMMGPP-----PGMRPPMGP-----PMGIP 206
             + G P   PPG GG P   G    A  PG++GP      PG R   G      P G+P
Sbjct: 596 QGLPGPPG--PPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP 653

Query: 207 PGRGTPMGMPPPGMRPP--PPGMRGPP 231
              GTP    P G   P  PPG +GPP
Sbjct: 654 ---GTPGTDGPKGASGPAGPPGAQGPP 677



 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 46/142 (32%), Positives = 49/142 (34%), Gaps = 28/142 (19%)

Query: 115 PAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGG 174
           P G P PQ PAG  GP RG  G   +   P  RG                    PPG  G
Sbjct: 49  PKGPPGPQGPAGEQGP-RGDRGDKGEKGAPGPRGRDGEPGTPGNPG--------PPGPPG 99

Query: 175 PPPPMG----------------RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPP 218
           PP P G                 G    G+M  P G   P GPP   P G   P G    
Sbjct: 100 PPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPG--PAGAPGPQGFQGN 157

Query: 219 GMRPPPPGMRGPPPPGMRPPRP 240
              P  PG+ GP  P   PP P
Sbjct: 158 PGEPGEPGVSGPMGP-RGPPGP 178



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 50/163 (30%), Positives = 61/163 (37%), Gaps = 26/163 (15%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAAT 158
           G  G PG     G+  P+G P      G  GP +G  G    +  P  +G       A  
Sbjct: 492 GLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGP-QGARGQPGVMGFPGPKGANGEPGKAGE 550

Query: 159 ASIAGAP-------TQYPPGRGGPPPPMG-------RGAPPPGMMGPPPGMRPPMGPPM- 203
             + GAP            G  GPP P G       +GAP P      PG   P GPP  
Sbjct: 551 KGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPG---PPGPPGE 607

Query: 204 -GIPPGRGTPMGMPPPGMRPPP-----PGMRGPP-PPGMRPPR 239
            G P  +G P     PG+  P      PG RG P   G++ PR
Sbjct: 608 GGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPR 650



 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 62/212 (29%), Positives = 75/212 (35%), Gaps = 47/212 (22%)

Query: 40  LILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPP-PKDTGIARVPLA 98
           ++ C   + R+  PK  K    + K ++G              +GPP P+     + P  
Sbjct: 20  VLRCQGQDVRQPGPKGQKGEPGDIKDIVG-------------PKGPPGPQGPAGEQGPRG 66

Query: 99  -----GAAGGPGI-GRAAGRGIPA-----GVPMPQAPAGLAGPVRGVGGPSQQVMTPQGR 147
                G  G PG  GR    G P      G P P  P GL G               Q  
Sbjct: 67  DRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGN-----------FAAQMA 115

Query: 148 GTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAP-PPGMMGPP-----PGMRPPMGP 201
           G     A  A   +   P   P G  GPP P   GAP P G  G P     PG+  PMGP
Sbjct: 116 GGFDEKAGGAQLGVMQGP-MGPMGPRGPPGP--AGAPGPQGFQGNPGEPGEPGVSGPMGP 172

Query: 202 PMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPP 233
               PPG     G      +P   G RGPP P
Sbjct: 173 RG--PPGPPGKPGDDGEAGKPGKAGERGPPGP 202



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 54/162 (33%), Positives = 61/162 (37%), Gaps = 20/162 (12%)

Query: 86  PPKDTGIARVPLAGA----AGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQ- 140
           PP   G     +AG     AGG  +G   G   P G   P  PAG  GP    G P +  
Sbjct: 103 PPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG 162

Query: 141 ---VMTPQG-RGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG-RGAP-PPGMMGPP-- 192
              V  P G RG             AG P +   G  GPP P G RG P  PG+ G    
Sbjct: 163 EPGVSGPMGPRGPPGPPGKPGDDGEAGKPGK--AGERGPPGPQGARGFPGTPGLPGVKGH 220

Query: 193 ---PGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPP 231
              PG+    G   G P  +G   G P     P P G RG P
Sbjct: 221 RGYPGLDGAKG-EAGAPGVKG-ESGSPGENGSPGPMGPRGLP 260



 Score = 41.2 bits (95), Expect = 8e-04
 Identities = 59/202 (29%), Positives = 65/202 (32%), Gaps = 52/202 (25%)

Query: 83   EGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGP----- 137
            EGPP       +  + G  G  G     G   P+G P  Q   G +G  RG  GP     
Sbjct: 899  EGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGD-RGPPGPVGPPG 957

Query: 138  ------------SQQVMTPQGR-GTVAAAAAAATASIAGAP-TQYPPGRGGPPPPMGR-- 181
                        S     P GR G              GAP    PPG  GP  P G+  
Sbjct: 958  LTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1017

Query: 182  ---GAPPPGMMGP--PPGMRPPMGP--PMGIPPGRGTP--------------MGMP-PPG 219
                A   G MGP  P G R   GP  P G     G P               G+P PPG
Sbjct: 1018 DRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPG 1077

Query: 220  MR--------PPPPGMRGPPPP 233
                        P G RGPP P
Sbjct: 1078 PSGDQGASGPAGPSGPRGPPGP 1099



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 34/107 (31%), Positives = 39/107 (36%), Gaps = 16/107 (14%)

Query: 97   LAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGP-----VRGVGGPSQQVMTPQGRGTVA 151
            L G  G PG     G   PAG   P+ P G  GP       G+ GP   +  P  RG   
Sbjct: 1069 LQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGP---IGPPGPRGR-- 1123

Query: 152  AAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPP 198
                +     AG P    PG  GPP P G G       G  P  + P
Sbjct: 1124 ----SGETGPAGPPGN--PGPPGPPGPPGPGIDMSAFAGLGPREKGP 1164



 Score = 37.0 bits (84), Expect = 0.015
 Identities = 50/159 (31%), Positives = 58/159 (36%), Gaps = 47/159 (29%)

Query: 82   VEGP--PPKDTGIARVP----LAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVG 135
            ++GP  P  D G A  P    L G  G  G+    G   P+G      PAG +GP RG  
Sbjct: 1039 IQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGP-RGPP 1097

Query: 136  GPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGA------PPPGMM 189
            GP    + P G+                      PG  GPP P GR        PP    
Sbjct: 1098 GP----VGPSGKDGANGI----------------PGPIGPPGPRGRSGETGPAGPPGNP- 1136

Query: 190  GPPPGMRPPMGPPMGIPPGRGTPM----GMPPPGMRPPP 224
            GPP       GPP   PPG G  M    G+ P    P P
Sbjct: 1137 GPP-------GPPG--PPGPGIDMSAFAGLGPREKGPDP 1166



 Score = 33.9 bits (76), Expect = 0.13
 Identities = 29/70 (41%), Positives = 30/70 (42%), Gaps = 16/70 (22%)

Query: 171 GRGGPPPPMGRGAPPPGMMGP--PPGMRPPMGPPMGIPPGR----GTPMGMPPPGMRPPP 224
           G  GPP P G    P G  GP    G +   G P   P GR    GTP    PPG    P
Sbjct: 48  GPKGPPGPQG----PAGEQGPRGDRGDKGEKGAPG--PRGRDGEPGTPGNPGPPG----P 97

Query: 225 PGMRGPPPPG 234
           PG  GPP  G
Sbjct: 98  PGPPGPPGLG 107


>gi|4507127 small nuclear ribonucleoprotein polypeptide C [Homo
           sapiens]
          Length = 159

 Score = 68.9 bits (167), Expect = 4e-12
 Identities = 48/115 (41%), Positives = 52/115 (45%), Gaps = 14/115 (12%)

Query: 139 QQVMTPQGRGTVAAAAAA-ATASIAGAPTQYPPGRGG--PPPPMGRGAPPPGMMGPPPGM 195
           Q+ M  Q +  +    AA     I   P   PP  G   PPPP   G P PGMM  P   
Sbjct: 39  QKWMEEQAQSLIDKTTAAFQQGKIPPTPFSAPPPAGAMIPPPPSLPGPPRPGMMPAPHMG 98

Query: 196 RPPMGPPMGIPPGRGTPMGMPPPGMRPP----------PPGMRGPPPPGMRPPRP 240
            PPM P MG PP    P+G P PGMRPP          PP MR P  P M P RP
Sbjct: 99  GPPMMPMMGPPPPGMMPVG-PAPGMRPPMGGHMPMMPGPPMMRPPARPMMVPTRP 152



 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 44/101 (43%), Positives = 46/101 (45%), Gaps = 13/101 (12%)

Query: 143 TPQGRGTVAAAAAAATASIAGAPT---QYPPGRGGPPPPMGRGAPPPGMM--GPPPGMRP 197
           TP      A A      S+ G P       P  GGPP     G PPPGMM  GP PGMRP
Sbjct: 65  TPFSAPPPAGAMIPPPPSLPGPPRPGMMPAPHMGGPPMMPMMGPPPPGMMPVGPAPGMRP 124

Query: 198 PMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPPGMRPP 238
           PMG  M + PG        PP MRPP   M  P  PGM  P
Sbjct: 125 PMGGHMPMMPG--------PPMMRPPARPMMVPTRPGMTRP 157


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.142    0.455 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,616,330
Number of Sequences: 37866
Number of extensions: 1693618
Number of successful extensions: 46122
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 991
Number of HSP's successfully gapped in prelim test: 1868
Number of HSP's that attempted gapping in prelim test: 10595
Number of HSP's gapped (non-prelim): 14931
length of query: 240
length of database: 18,247,518
effective HSP length: 99
effective length of query: 141
effective length of database: 14,498,784
effective search space: 2044328544
effective search space used: 2044328544
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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