BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|24586686 voltage-dependent calcium channel gamma-8 subunit [Homo sapiens] (425 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|24586686 voltage-dependent calcium channel gamma-8 subunit [H... 863 0.0 gi|7656948 voltage-dependent calcium channel gamma-4 subunit [Ho... 379 e-105 gi|5174405 voltage-dependent calcium channel gamma-2 subunit [Ho... 342 5e-94 gi|5729756 voltage-dependent calcium channel gamma-3 subunit [Ho... 329 3e-90 gi|22027551 voltage-dependent calcium channel gamma-5 subunit is... 118 9e-27 gi|7656950 voltage-dependent calcium channel gamma-5 subunit iso... 110 2e-24 gi|21361975 voltage-dependent calcium channel gamma-7 subunit [H... 105 8e-23 gi|55956899 keratin 9 [Homo sapiens] 65 1e-10 gi|47132620 keratin 2 [Homo sapiens] 64 3e-10 gi|119395750 keratin 1 [Homo sapiens] 62 8e-10 gi|18375613 dachshund homolog 1 isoform b [Homo sapiens] 62 1e-09 gi|18375611 dachshund homolog 1 isoform a [Homo sapiens] 62 1e-09 gi|18375609 dachshund homolog 1 isoform c [Homo sapiens] 62 1e-09 gi|110832843 TBP-associated factor 4 [Homo sapiens] 62 1e-09 gi|4504733 insulin receptor substrate 4 [Homo sapiens] 60 5e-09 gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] 59 6e-09 gi|109255251 loricrin [Homo sapiens] 59 1e-08 gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens] 58 1e-08 gi|51479192 ring finger protein 1 [Homo sapiens] 58 2e-08 gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens] 57 2e-08 gi|226437592 transmembrane protein 114 [Homo sapiens] 57 2e-08 gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homol... 57 4e-08 gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolo... 57 4e-08 gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 57 4e-08 gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 57 4e-08 gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 57 4e-08 gi|195972866 keratin 10 [Homo sapiens] 56 5e-08 gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo... 56 7e-08 gi|33620755 YEATS domain containing 2 [Homo sapiens] 56 7e-08 gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens] 55 9e-08 >gi|24586686 voltage-dependent calcium channel gamma-8 subunit [Homo sapiens] Length = 425 Score = 863 bits (2229), Expect = 0.0 Identities = 425/425 (100%), Positives = 425/425 (100%) Query: 1 MESLKRWNEERGLWCEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAG 60 MESLKRWNEERGLWCEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAG Sbjct: 1 MESLKRWNEERGLWCEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAG 60 Query: 61 GDDGTPHRGGGGASEKKDPGGLTHSGLWRICCLEGLKRGVCVKINHFPEDTDYDHDSAEY 120 GDDGTPHRGGGGASEKKDPGGLTHSGLWRICCLEGLKRGVCVKINHFPEDTDYDHDSAEY Sbjct: 61 GDDGTPHRGGGGASEKKDPGGLTHSGLWRICCLEGLKRGVCVKINHFPEDTDYDHDSAEY 120 Query: 121 LLRVVRASSIFPILSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVY 180 LLRVVRASSIFPILSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVY Sbjct: 121 LLRVVRASSIFPILSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVY 180 Query: 181 ISANAGEPGPKRDEEKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRS 240 ISANAGEPGPKRDEEKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRS Sbjct: 181 ISANAGEPGPKRDEEKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRS 240 Query: 241 DLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFA 300 DLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFA Sbjct: 241 DLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFA 300 Query: 301 STDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRG 360 STDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRG Sbjct: 301 STDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRG 360 Query: 361 GASGFLTLHNAFPKEAGGGVTVTVTGPPAPPAPAPPAPSAPAPGTLAKEAAASNTNTLNR 420 GASGFLTLHNAFPKEAGGGVTVTVTGPPAPPAPAPPAPSAPAPGTLAKEAAASNTNTLNR Sbjct: 361 GASGFLTLHNAFPKEAGGGVTVTVTGPPAPPAPAPPAPSAPAPGTLAKEAAASNTNTLNR 420 Query: 421 KTTPV 425 KTTPV Sbjct: 421 KTTPV 425 >gi|7656948 voltage-dependent calcium channel gamma-4 subunit [Homo sapiens] Length = 327 Score = 379 bits (973), Expect = e-105 Identities = 194/307 (63%), Positives = 233/307 (75%), Gaps = 21/307 (6%) Query: 15 CEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGAS 74 C++G+Q+LLTT GAFAAF LM IAI TDYWLY+ A ICN TNLT DDG P R Sbjct: 4 CDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTM--DDGPPPR------ 55 Query: 75 EKKDPGGLTHSGLWRICCLEGLKRGVCVKINHFPEDTDYDHDSAEYLLRVVRASSIFPIL 134 + G LTHSGLWR+CC+EG+ +G C +INHFPED DYDHDS+EYLLR+VRASS+FPIL Sbjct: 56 --RARGDLTHSGLWRVCCIEGIYKGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPIL 113 Query: 135 SAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISANAGEPGPKRDE 194 S ILLLLGG+C+ A R+Y K NI+L AGILFVAAGLSNIIG+IVYIS+N G+P KRDE Sbjct: 114 STILLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDE 173 Query: 195 EKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRSDLLKAGGGAGGSGG 254 +KKNHY+YGWSFYFG LSFI+AE +GVLAVNIYIE+++E +++ + LKA Sbjct: 174 DKKNHYNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKA--------- 224 Query: 255 SGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPG-FASTDISMYTLSRDP 313 S S R+PSYR+R RRRSRSSSRS+E SPSRD SP G G ++SMYTLSR+P Sbjct: 225 SSSSPYARMPSYRYR-RRRSRSSSRSTEASPSRDVSPMGLKITGAIPMGELSMYTLSREP 283 Query: 314 SKGSVAA 320 K + AA Sbjct: 284 LKVTTAA 290 >gi|5174405 voltage-dependent calcium channel gamma-2 subunit [Homo sapiens] Length = 323 Score = 342 bits (876), Expect = 5e-94 Identities = 180/304 (59%), Positives = 226/304 (74%), Gaps = 29/304 (9%) Query: 16 EKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGASE 75 ++GVQ+LLTTVGAFAAF LMTIA+ TDYWLY+R +C T +++ + Sbjct: 5 DRGVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRG-VCKTKSVSEN------------ETS 51 Query: 76 KKDPGGLTHSGLWRICCLEGLKRGVCVKINHFPEDTDYDHDSAEYLLRVVRASSIFPILS 135 KK+ +THSGLWR CCLEG +G+C +I+HFPED DY+ D+AEY LR VRASSIFPILS Sbjct: 52 KKNEEVMTHSGLWRTCCLEGNFKGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILS 111 Query: 136 AILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISANAGEPGPKRDEE 195 ILL +GG+C+AAS YK++ NIIL AGI FV+AGLSNIIG+IVYISANAG+ P + + Sbjct: 112 VILLFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGD--PSKSDS 169 Query: 196 KKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSR-SDLLKAGGGAGGSGG 254 KKN YSYGWSFYFG LSFI+AE++GVLAV+++I+R ++ +R +D L+A Sbjct: 170 KKNSYSYGWSFYFGALSFIIAEMVGVLAVHMFIDRHKQLRATARATDYLQA--------- 220 Query: 255 SGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGG-PGGPGFASTDISMYTLSRDP 313 SAI R+PSYR+RY+RRSRSSSRS+EPS SRDASP G G ST+ISMYTLSRDP Sbjct: 221 ---SAITRIPSYRYRYQRRSRSSSRSTEPSHSRDASPVGIKGFNTLPSTEISMYTLSRDP 277 Query: 314 SKGS 317 K + Sbjct: 278 LKAA 281 >gi|5729756 voltage-dependent calcium channel gamma-3 subunit [Homo sapiens] Length = 315 Score = 329 bits (844), Expect = 3e-90 Identities = 172/301 (57%), Positives = 214/301 (71%), Gaps = 31/301 (10%) Query: 15 CEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGAS 74 C++G+Q+L+TTVGAFAAF LMTIA+ TDYWLY+R +C T + + + Sbjct: 4 CDRGIQMLITTVGAFAAFSLMTIAVGTDYWLYSRG-VCRTKSTS------------DNET 50 Query: 75 EKKDPGGLTHSGLWRICCLEGLKRGVCVKINHFPEDTDYDHDSAEYLLRVVRASSIFPIL 134 +K+ +THSGLWR CCLEG RGVC KI+HFPED DY+ D+AEYLLR VRASS+FPIL Sbjct: 51 SRKNEEVMTHSGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPIL 110 Query: 135 SAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISANAGEPGPKRDE 194 S LL GG+CVAAS ++S+ N+IL AGI FV+AGLSNIIG+IVYISANAG+PG + Sbjct: 111 SVTLLFFGGLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQR--- 167 Query: 195 EKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRSDLLKAGGGAGGSGG 254 + K YSYGWSFYFG SFI+AE++GV+AV+IYIE+ ++ +S S+ LK Sbjct: 168 DSKKSYSYGWSFYFGAFSFIIAEIVGVVAVHIYIEKHQQLRAKSHSEFLK---------- 217 Query: 255 SGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDISMYTLSRDPS 314 S RLP YR+R+RR RSSSRS+EP SRD SP G STDISM+TLSRDPS Sbjct: 218 --KSTFARLPPYRYRFRR--RSSSRSTEPR-SRDLSPISKGFHTIPSTDISMFTLSRDPS 272 Query: 315 K 315 K Sbjct: 273 K 273 >gi|22027551 voltage-dependent calcium channel gamma-5 subunit isoform a [Homo sapiens] Length = 275 Score = 118 bits (296), Expect = 9e-27 Identities = 67/218 (30%), Positives = 114/218 (52%), Gaps = 20/218 (9%) Query: 15 CEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGAS 74 C + LL++V A GL+ IA+STDYWLY + N Sbjct: 4 CGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQN------------------ 45 Query: 75 EKKDPGGLTHSGLWRICCLEGLKRGVCVKINH-FPEDTDYDHDSAEYLLRVVRASSIFPI 133 + + HSGLWR+C L G +RG C I + P +T +S +L+++R+++ FP+ Sbjct: 46 QSTEIKMSLHSGLWRVCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPL 105 Query: 134 LSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISA-NAGEPGPKR 192 +S + +G + + + + +GI F+ +GLS ++G+++YIS+ N + Sbjct: 106 VSLFFMFIGFILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTK 165 Query: 193 DEEKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIER 230 D E +Y YGWSF F +SF+L E GV++V ++++R Sbjct: 166 DAETYFNYKYGWSFAFAAISFLLTESAGVMSVYLFMKR 203 >gi|7656950 voltage-dependent calcium channel gamma-5 subunit isoform b [Homo sapiens] Length = 296 Score = 110 bits (276), Expect = 2e-24 Identities = 64/206 (31%), Positives = 105/206 (50%), Gaps = 20/206 (9%) Query: 15 CEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGAS 74 C + LL++V A GL+ IA+STDYWLY + N Sbjct: 4 CGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQN------------------ 45 Query: 75 EKKDPGGLTHSGLWRICCLEGLKRGVCVKINH-FPEDTDYDHDSAEYLLRVVRASSIFPI 133 + + HSGLWR+C L G +RG C I + P +T +S +L+++R+++ FP+ Sbjct: 46 QSTEIKMSLHSGLWRVCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPL 105 Query: 134 LSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISA-NAGEPGPKR 192 +S + +G + + + + +GI F+ +GLS ++G+++YIS+ N + Sbjct: 106 VSLFFMFIGFILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTK 165 Query: 193 DEEKKNHYSYGWSFYFGGLSFILAEV 218 D E +Y YGWSF F +SF+L EV Sbjct: 166 DAETYFNYKYGWSFAFAAISFLLTEV 191 >gi|21361975 voltage-dependent calcium channel gamma-7 subunit [Homo sapiens] Length = 275 Score = 105 bits (262), Expect = 8e-23 Identities = 67/221 (30%), Positives = 108/221 (48%), Gaps = 20/221 (9%) Query: 15 CEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGAS 74 C LL++V L+ IA+STDYWLY ++GT Sbjct: 4 CSSRALTLLSSVFGACGLLLVGIAVSTDYWLYM--------------EEGTVLPQNQTTE 49 Query: 75 EKKDPGGLTHSGLWRICCLEGLKRGVCVKINHFPE-DTDYDHDSAEYLLRVVRASSIFPI 133 K H+GLWR+C G ++G CV +F E + + ++ E +L+ VR ++ FP+ Sbjct: 50 VKM----ALHAGLWRVCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPM 105 Query: 134 LSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISA-NAGEPGPKR 192 +S L+ V + + + +GI F+ +GLS ++G+++YIS+ N Sbjct: 106 VSLFLVFTAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPS 165 Query: 193 DEEKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSRE 233 E+ HY YGWSF F SF+L E GV++V ++ +R E Sbjct: 166 SSEQYFHYRYGWSFAFAASSFLLKEGAGVMSVYLFTKRYAE 206 >gi|55956899 keratin 9 [Homo sapiens] Length = 623 Score = 65.1 bits (157), Expect = 1e-10 Identities = 49/133 (36%), Positives = 55/133 (41%), Gaps = 7/133 (5%) Query: 238 SRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPS-----PSRDASPG 292 S S L ++GGG GG GSG S +R RF R S S SR G Sbjct: 7 SSSYLSRSGGGGGGGLGSGGS--IRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRG 64 Query: 293 GPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGG 352 G G G++ S S G G G GG GG + GG GG GGG GGG G Sbjct: 65 GGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFG 124 Query: 353 AGAERDRGGASGF 365 G GG GF Sbjct: 125 GGYGSGFGGFGGF 137 Score = 59.3 bits (142), Expect = 6e-09 Identities = 50/141 (35%), Positives = 59/141 (41%), Gaps = 27/141 (19%) Query: 247 GGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDISM 306 GG GGSGGS Y R SR S S S GG GG G S S Sbjct: 476 GGRGGSGGS--------------YGRGSRGGSGGSY---GGGGSGGGYGG-GSGSRGGSG 517 Query: 307 YTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAG---------GGGGGGGGAGAER 357 + G + G G G GGG + G+ GG +GG+G GGG GGG G Sbjct: 518 GSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSG 577 Query: 358 DRGGASGFLTLHNAFPKEAGG 378 RGG+ G + F E+GG Sbjct: 578 SRGGSGGSHGGGSGFGGESGG 598 Score = 51.2 bits (121), Expect = 2e-06 Identities = 37/109 (33%), Positives = 45/109 (41%), Gaps = 10/109 (9%) Query: 261 LRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAA 320 +RL Y E S + GG GG G S SR S GS Sbjct: 445 MRLEKEIETYHNLLEGGQEDFESSGAGKIGLGGRGGSGG-----SYGRGSRGGSGGSYGG 499 Query: 321 GLAGAGGGGG-----GAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASG 364 G +G G GGG G+ G++GG +G GG GGG GG GG+ G Sbjct: 500 GGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGG 548 Score = 47.8 bits (112), Expect = 2e-05 Identities = 40/127 (31%), Positives = 50/127 (39%), Gaps = 12/127 (9%) Query: 247 GGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGP---GFASTD 303 GG+GGS G G S Y R S S S S GG GG G + Sbjct: 491 GGSGGSYGGGGSG----GGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGS 546 Query: 304 ISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGG-----GGGGAGAERD 358 ++ + G + G+GGG GG G+ GG+ G GGG G GG G E Sbjct: 547 GGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEA 606 Query: 359 RGGASGF 365 G G+ Sbjct: 607 SGSGGGY 613 Score = 44.7 bits (104), Expect = 2e-04 Identities = 40/123 (32%), Positives = 48/123 (39%), Gaps = 15/123 (12%) Query: 246 GGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGG--PGFASTD 303 GGG+G GGSG S + S S S GG GG G + + Sbjct: 507 GGGSGSRGGSGGS---------YGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGN 557 Query: 304 ISMYTLSRDPSKGSVAAGLAGAGGGGG--GAVGAFGGAAGGAGGGGGGGGGAGAERDRGG 361 + S S G G GG GG G FGG +GG+ GGG G+G GG Sbjct: 558 YGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGG--GYGG 615 Query: 362 ASG 364 SG Sbjct: 616 GSG 618 Score = 44.7 bits (104), Expect = 2e-04 Identities = 35/120 (29%), Positives = 41/120 (34%), Gaps = 48/120 (40%) Query: 245 AGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDI 304 +GGG GG G G S GG GG Sbjct: 530 SGGGYGGGSGGGHS---------------------------------GGSGG-------- 548 Query: 305 SMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASG 364 G G +G+GGG GG G G+ GG+GG GGG G G E GG+ G Sbjct: 549 -----GHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGE--SGGSYG 601 Score = 43.9 bits (102), Expect = 3e-04 Identities = 29/68 (42%), Positives = 36/68 (52%), Gaps = 3/68 (4%) Query: 314 SKGSVAAGLAGAGGGGGG-AVGAFGGAAGGAGGGG-GGGGGAGAERDRGGASGFLTLHNA 371 S G+ GL G GG GG G+ GG+ G GGGG GGG G G+ RGG+ G + Sbjct: 467 SSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGS-GSRGGSGGSYGGGSG 525 Query: 372 FPKEAGGG 379 +GGG Sbjct: 526 SGGGSGGG 533 >gi|47132620 keratin 2 [Homo sapiens] Length = 639 Score = 63.5 bits (153), Expect = 3e-10 Identities = 50/136 (36%), Positives = 62/136 (45%), Gaps = 20/136 (14%) Query: 231 SREAHCQSRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDAS 290 S + C+SR + GGG G G S SA++ SR S+ S Sbjct: 2 SCQISCKSRG---RGGGGGGFRGFSSGSAVVS---------GGSRRSTSSFSCLSRHGGG 49 Query: 291 PGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGG-GAVGAFGGAAGGAGGGGGG 349 GG GG GF S S+ L G+ + ++ AGGGGG GA G FGG GG GGG Sbjct: 50 GGGFGGGGFGSR--SLVGLG-----GTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSF 102 Query: 350 GGGAGAERDRGGASGF 365 GGG+G G GF Sbjct: 103 GGGSGFSGGGFGGGGF 118 Score = 57.4 bits (137), Expect = 2e-08 Identities = 42/133 (31%), Positives = 54/133 (40%), Gaps = 29/133 (21%) Query: 250 GGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDISMYTL 309 GGSGG G S+ SS SS S R + G G G Sbjct: 519 GGSGGRGSSS------------GGGYSSGSSSYGSGGRQSGSRGGSGGG----------- 555 Query: 310 SRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASGFLTLH 369 GS++ G G+GGG GG G+ GG+ GG+ GGG G G G GG+ G + Sbjct: 556 ------GSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSG 609 Query: 370 NAFPKEAGGGVTV 382 + GG +V Sbjct: 610 GGYGSGGGGSSSV 622 Score = 39.3 bits (90), Expect = 0.007 Identities = 29/78 (37%), Positives = 35/78 (44%), Gaps = 5/78 (6%) Query: 289 ASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGG- 347 A+ GG GG G +S+ + S G +G G GGGG G GG G G GG Sbjct: 516 AAFGGSGGRG-SSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISG--GGYGSGGGSGGR 572 Query: 348 -GGGGGAGAERDRGGASG 364 G GGG+ GG G Sbjct: 573 YGSGGGSKGGSISGGGYG 590 Score = 37.7 bits (86), Expect = 0.020 Identities = 34/120 (28%), Positives = 40/120 (33%), Gaps = 51/120 (42%) Query: 245 AGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDI 304 +GGG G GGSG R S GG Sbjct: 559 SGGGYGSGGGSG-----------------------------GRYGSGGG----------- 578 Query: 305 SMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASG 364 SKG +G G G GGG + GG+ GG+ GGG G G G G+SG Sbjct: 579 ---------SKGGSISG--GGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSSSVKGSSG 627 Score = 35.8 bits (81), Expect = 0.076 Identities = 27/76 (35%), Positives = 33/76 (43%), Gaps = 20/76 (26%) Query: 308 TLSRDPSKGSVAAGLAGAGG-----GGG--------GAVGAFGGAAGGAGGGG------- 347 T S S + A G+GG GGG G+ G G+ GG+GGGG Sbjct: 504 TSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGY 563 Query: 348 GGGGGAGAERDRGGAS 363 G GGG+G GG S Sbjct: 564 GSGGGSGGRYGSGGGS 579 Score = 35.0 bits (79), Expect = 0.13 Identities = 27/73 (36%), Positives = 32/73 (43%), Gaps = 20/73 (27%) Query: 324 GAGGGGGGAVGAFGGAA---GGA--------------GGGGGGGGGAGAERDRGGASGFL 366 G GGGGGG G G+A GG+ GGGGG GGG R G G Sbjct: 11 GRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGTK 70 Query: 367 TLHNAFPKEAGGG 379 ++ + AGGG Sbjct: 71 SISISV---AGGG 80 Score = 34.3 bits (77), Expect = 0.22 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 9/72 (12%) Query: 301 STDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGG------GGGGGGG-- 352 + ++ T+S + + + G G G GG + G ++ G+GG GG GGGG Sbjct: 500 TVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSS-GSSSYGSGGRQSGSRGGSGGGGSI 558 Query: 353 AGAERDRGGASG 364 +G GG SG Sbjct: 559 SGGGYGSGGGSG 570 >gi|119395750 keratin 1 [Homo sapiens] Length = 644 Score = 62.4 bits (150), Expect = 8e-10 Identities = 54/156 (34%), Positives = 68/156 (43%), Gaps = 10/156 (6%) Query: 238 SRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSS-RSSEPSPSRDASPGGPGG 296 SR ++G +GG SG + I+ Y+RR+ SSS R S R +S GG GG Sbjct: 2 SRQFSSRSGYRSGGGFSSGSAGIIN-------YQRRTTSSSTRRSGGGGGRFSSCGGGGG 54 Query: 297 PGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAE 356 A +L S++ +A GG G G G +GG G GG GGGG G G Sbjct: 55 SFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGG- 113 Query: 357 RDRGGASGFLTLHNAFPKEA-GGGVTVTVTGPPAPP 391 GG GF + F GGG GP PP Sbjct: 114 IGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPP 149 Score = 53.5 bits (127), Expect = 4e-07 Identities = 45/128 (35%), Positives = 52/128 (40%), Gaps = 27/128 (21%) Query: 238 SRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGP 297 S S +GGG+ G GG G S SS S GG GG Sbjct: 506 STSHTTISGGGSRGGGGGG------------------YGSGGSSYGSGGGSYGSGGGGGG 547 Query: 298 GFASTDISMYTLSRDPSKGSVAAGLAGAGGGGG--GAVGAFGGAAGGAGGGGGGGGGAGA 355 G S S S GS G G+GGGGG G+ G+ + G GG GGGGGG+ Sbjct: 548 GRGSYG------SGGSSYGS-GGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSG 600 Query: 356 ERDRGGAS 363 R GG S Sbjct: 601 GRGSGGGS 608 Score = 48.5 bits (114), Expect = 1e-05 Identities = 35/95 (36%), Positives = 46/95 (48%), Gaps = 17/95 (17%) Query: 277 SSRSSEPSPSRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAF 336 S +S + S S GG GG G+ S S GS G G+GGGGGG G++ Sbjct: 504 SVSTSHTTISGGGSRGGGGG-GYGSGGSSY---------GS-GGGSYGSGGGGGGGRGSY 552 Query: 337 G------GAAGGAGGGGGGGGGAGAERDRGGASGF 365 G G+ GG+ G GGGGGG G+ + G+ Sbjct: 553 GSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGY 587 Score = 45.1 bits (105), Expect = 1e-04 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 5/79 (6%) Query: 301 STDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRG 360 + +S+ T S G G G G GG + G+ GG+ G GGGGGG G G+ Sbjct: 500 NVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSY 559 Query: 361 GASGFLTLHNAFPKEAGGG 379 G+ G ++ GGG Sbjct: 560 GSGG-----GSYGSGGGGG 573 Score = 44.3 bits (103), Expect = 2e-04 Identities = 44/140 (31%), Positives = 55/140 (39%), Gaps = 43/140 (30%) Query: 245 AGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDI 304 +GGG+ GSGG G R S S SS S GG GG Sbjct: 534 SGGGSYGSGGGGGGG------------RGSYGSGGSSYGSGGGSYGSGGGGG-------- 573 Query: 305 SMYTLSRDPSKGSVAAGLAGAG--GGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGA 362 GS +G + G GG G G GG++GG G GGG GG+ RG + Sbjct: 574 ---------GHGSYGSGSSSGGYRGGSG---GGGGGSSGGRGSGGGSSGGSIG--GRGSS 619 Query: 363 SGFLTLHNAFPKEAGGGVTV 382 SG + K +GG +V Sbjct: 620 SGGV-------KSSGGSSSV 632 >gi|18375613 dachshund homolog 1 isoform b [Homo sapiens] Length = 558 Score = 62.0 bits (149), Expect = 1e-09 Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 23/160 (14%) Query: 274 SRSSSRSSEPSPSRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAV 333 S SSS ++ + S +SP GP AS+ +++ S + AA + GGGGGG Sbjct: 23 SASSSGTTTSTSSATSSPAPSIGPP-ASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGG 81 Query: 334 GAFGGAAGGAGGGGGGGGG--------AGAERDRGGASGFLTLHNAFPKEAGGGVTVTVT 385 GG + G GGGGGGGGG A A GG G ++ AGGGV Sbjct: 82 SGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGIS--------AGGGVA---- 129 Query: 386 GPPAPPAPAPPAPSAPAPGTLAKEAAASNTNTLNRKTTPV 425 + P A S+ + + + +++S++++ + P+ Sbjct: 130 --SSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPL 167 Score = 47.0 bits (110), Expect = 3e-05 Identities = 36/148 (24%), Positives = 57/148 (38%), Gaps = 22/148 (14%) Query: 276 SSSRSSEPSPSRDASPGGPGGPGF--------ASTDISMYTLSRDPSKGSVAAGLAGAGG 327 +SS +S P+PS P GP A+ + T + G + G G+ G Sbjct: 33 TSSATSSPAPS--IGPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSG 90 Query: 328 GGGGAVGAFGGA------------AGGAGGGGGGGGGAGAERDRGGASGFLTLHNAFPKE 375 GGG G GG+ +GG GGG GGG + ++G + ++ Sbjct: 91 NGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSS 150 Query: 376 AGGGVTVTVTGPPAPPAPAPPAPSAPAP 403 + + + + P P P S P+P Sbjct: 151 SSSSSSSSSSSSSCGPLPGKPVYSTPSP 178 Score = 33.1 bits (74), Expect = 0.49 Identities = 38/159 (23%), Positives = 51/159 (32%), Gaps = 52/159 (32%) Query: 246 GGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDIS 305 GGG GGSGG G S+ + GG GG G S Sbjct: 76 GGGGGGSGGGGGSS-----------------------------GNGGGGGGGGGGSN--- 103 Query: 306 MYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASGF 365 ++AA A G GGGG GG GGG G +S Sbjct: 104 --------CNPNLAA--ASNGSGGGG---------GGISAGGGVASSTPINASTGSSSSS 144 Query: 366 LTLHNAFPKEAGGGVTVTVTGP-PAPPAPAPPAPSAPAP 403 + ++ + + + GP P P + P+P P Sbjct: 145 SSSSSSSSSSSSSSSSSSSCGPLPGKPVYSTPSPVENTP 183 >gi|18375611 dachshund homolog 1 isoform a [Homo sapiens] Length = 706 Score = 62.0 bits (149), Expect = 1e-09 Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 23/160 (14%) Query: 274 SRSSSRSSEPSPSRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAV 333 S SSS ++ + S +SP GP AS+ +++ S + AA + GGGGGG Sbjct: 23 SASSSGTTTSTSSATSSPAPSIGPP-ASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGG 81 Query: 334 GAFGGAAGGAGGGGGGGGG--------AGAERDRGGASGFLTLHNAFPKEAGGGVTVTVT 385 GG + G GGGGGGGGG A A GG G ++ AGGGV Sbjct: 82 SGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGIS--------AGGGVA---- 129 Query: 386 GPPAPPAPAPPAPSAPAPGTLAKEAAASNTNTLNRKTTPV 425 + P A S+ + + + +++S++++ + P+ Sbjct: 130 --SSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPL 167 Score = 47.0 bits (110), Expect = 3e-05 Identities = 36/148 (24%), Positives = 57/148 (38%), Gaps = 22/148 (14%) Query: 276 SSSRSSEPSPSRDASPGGPGGPGF--------ASTDISMYTLSRDPSKGSVAAGLAGAGG 327 +SS +S P+PS P GP A+ + T + G + G G+ G Sbjct: 33 TSSATSSPAPS--IGPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSG 90 Query: 328 GGGGAVGAFGGA------------AGGAGGGGGGGGGAGAERDRGGASGFLTLHNAFPKE 375 GGG G GG+ +GG GGG GGG + ++G + ++ Sbjct: 91 NGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSS 150 Query: 376 AGGGVTVTVTGPPAPPAPAPPAPSAPAP 403 + + + + P P P S P+P Sbjct: 151 SSSSSSSSSSSSSCGPLPGKPVYSTPSP 178 Score = 33.1 bits (74), Expect = 0.49 Identities = 38/159 (23%), Positives = 51/159 (32%), Gaps = 52/159 (32%) Query: 246 GGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDIS 305 GGG GGSGG G S+ + GG GG G S Sbjct: 76 GGGGGGSGGGGGSS-----------------------------GNGGGGGGGGGGSN--- 103 Query: 306 MYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASGF 365 ++AA A G GGGG GG GGG G +S Sbjct: 104 --------CNPNLAA--ASNGSGGGG---------GGISAGGGVASSTPINASTGSSSSS 144 Query: 366 LTLHNAFPKEAGGGVTVTVTGP-PAPPAPAPPAPSAPAP 403 + ++ + + + GP P P + P+P P Sbjct: 145 SSSSSSSSSSSSSSSSSSSCGPLPGKPVYSTPSPVENTP 183 >gi|18375609 dachshund homolog 1 isoform c [Homo sapiens] Length = 504 Score = 62.0 bits (149), Expect = 1e-09 Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 23/160 (14%) Query: 274 SRSSSRSSEPSPSRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAV 333 S SSS ++ + S +SP GP AS+ +++ S + AA + GGGGGG Sbjct: 23 SASSSGTTTSTSSATSSPAPSIGPP-ASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGG 81 Query: 334 GAFGGAAGGAGGGGGGGGG--------AGAERDRGGASGFLTLHNAFPKEAGGGVTVTVT 385 GG + G GGGGGGGGG A A GG G ++ AGGGV Sbjct: 82 SGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGIS--------AGGGVA---- 129 Query: 386 GPPAPPAPAPPAPSAPAPGTLAKEAAASNTNTLNRKTTPV 425 + P A S+ + + + +++S++++ + P+ Sbjct: 130 --SSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPL 167 Score = 47.0 bits (110), Expect = 3e-05 Identities = 36/148 (24%), Positives = 57/148 (38%), Gaps = 22/148 (14%) Query: 276 SSSRSSEPSPSRDASPGGPGGPGF--------ASTDISMYTLSRDPSKGSVAAGLAGAGG 327 +SS +S P+PS P GP A+ + T + G + G G+ G Sbjct: 33 TSSATSSPAPS--IGPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSG 90 Query: 328 GGGGAVGAFGGA------------AGGAGGGGGGGGGAGAERDRGGASGFLTLHNAFPKE 375 GGG G GG+ +GG GGG GGG + ++G + ++ Sbjct: 91 NGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSS 150 Query: 376 AGGGVTVTVTGPPAPPAPAPPAPSAPAP 403 + + + + P P P S P+P Sbjct: 151 SSSSSSSSSSSSSCGPLPGKPVYSTPSP 178 Score = 33.1 bits (74), Expect = 0.49 Identities = 38/159 (23%), Positives = 51/159 (32%), Gaps = 52/159 (32%) Query: 246 GGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDIS 305 GGG GGSGG G S+ + GG GG G S Sbjct: 76 GGGGGGSGGGGGSS-----------------------------GNGGGGGGGGGGSN--- 103 Query: 306 MYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASGF 365 ++AA A G GGGG GG GGG G +S Sbjct: 104 --------CNPNLAA--ASNGSGGGG---------GGISAGGGVASSTPINASTGSSSSS 144 Query: 366 LTLHNAFPKEAGGGVTVTVTGP-PAPPAPAPPAPSAPAP 403 + ++ + + + GP P P + P+P P Sbjct: 145 SSSSSSSSSSSSSSSSSSSCGPLPGKPVYSTPSPVENTP 183 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 62.0 bits (149), Expect = 1e-09 Identities = 67/262 (25%), Positives = 94/262 (35%), Gaps = 67/262 (25%) Query: 214 ILAEVIGVLAVNIYIERSREAHCQSRSDLLKAG-----------GGAGGSGGSGPSAILR 262 ++++++G L + + H R+ ++A G G+ G+GP+A Sbjct: 21 VVSDLVGSLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAE 80 Query: 263 -------LPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFA---STDISMYTLSRD 312 P R R R PSP R P GP P + S + + Sbjct: 81 GAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPV 140 Query: 313 PSKGSVAAGLAGAGGG-----GGGAVGAFGGAAGGAGGGGGGG------GGAGAERDRGG 361 P+ +VAAG A G G A+ A G G G G G G G GA + G Sbjct: 141 PAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNG 200 Query: 362 ASGFLTLHNA-----------------FPKEAGGGVTVTV------TGPPAPPAPAPPA- 397 ++ L H+A PK A G + PPAP AP+PPA Sbjct: 201 SAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAA 260 Query: 398 -----------PSAPAPGTLAK 408 P PAP TLA+ Sbjct: 261 PAPAAPAAAPPPPPPAPATLAR 282 Score = 45.8 bits (107), Expect = 7e-05 Identities = 42/145 (28%), Positives = 58/145 (40%), Gaps = 6/145 (4%) Query: 283 PSPSRDASPGG-PGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAG 341 P+P+ A P G P GP A+ + +++ A A A GG G G G A Sbjct: 275 PAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAA 334 Query: 342 GAGGGGGGGGGAGAERDRGGASGFLTLHNAFPKEAGGGVTVTVTGPPAPPAPAPPAPSAP 401 A G + + TL + P + + T A P+PA P P Sbjct: 335 AAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPP--P 392 Query: 402 APGT---LAKEAAASNTNTLNRKTT 423 APGT L K AA + T +L+R T Sbjct: 393 APGTPTGLPKGAAGAVTQSLSRTPT 417 >gi|4504733 insulin receptor substrate 4 [Homo sapiens] Length = 1257 Score = 59.7 bits (143), Expect = 5e-09 Identities = 53/174 (30%), Positives = 61/174 (35%), Gaps = 32/174 (18%) Query: 245 AGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDI 304 +G G G GG G + SSS SS + G GG G Sbjct: 495 SGNGRGSGGGQGSNG--------------QGSSSHSSGGNQCSGEGQGSRGGQGSNGQGS 540 Query: 305 SMYTLSRDPSKGSVAAGLAGAGGG----------GGGAVGAFGGAAGGAGGGGGGGGGAG 354 SRD G AG G+GGG GG G G+ GG GGG G G+G Sbjct: 541 GGNQCSRD---GQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSG 597 Query: 355 AERDRGGASGFLTLHNAFPKEAGGGVTVTVTGPPAPPAPAPPAPSAPAPGTLAK 408 D G G + K + G PP P PP P PA GT K Sbjct: 598 KGSDGDGERG-----KSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGK 646 Score = 28.9 bits (63), Expect = 9.3 Identities = 30/107 (28%), Positives = 40/107 (37%), Gaps = 4/107 (3%) Query: 261 LRLPSYRFRYRRRSRSSS--RSSEPSPSRDASPG-GPGGPGFASTDISMYTLSRDPSKGS 317 L LP R R S +S R PSP+R P P S+++S +G+ Sbjct: 414 LHLPRGRRSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGN 473 Query: 318 VAAGLAGAGGGGGGAVGAFGGAAGGAGGGGG-GGGGAGAERDRGGAS 363 G GG G+ G G GGG G G G+ G + Sbjct: 474 PQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN 520 >gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] Length = 474 Score = 59.3 bits (142), Expect = 6e-09 Identities = 50/172 (29%), Positives = 69/172 (40%), Gaps = 41/172 (23%) Query: 264 PSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLA 323 P Y++R R++ +S + +S S + + PG KG G Sbjct: 124 PDYKYRPRKKVKSGNANSSSSAAASSKPG---------------------EKGDKVGGSG 162 Query: 324 GAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGA-----------ERDRGGASGFLTLHNAF 372 G G GGGG GG + AGGGGGG G GA + GGA G ++ +A Sbjct: 163 GGGHGGGG-----GGGSSNAGGGGGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAK 217 Query: 373 PKEAGGGVTVTVTGPPAPPAPAPPAPSAPAPGTLAKEAAASNTNTLNRKTTP 424 AGGG G A A A A L AA++ ++L + TP Sbjct: 218 LILAGGG----GGGKAAAAAAASFAAEQAGAAALLPLGAAADHHSLYKARTP 265 Score = 34.7 bits (78), Expect = 0.17 Identities = 42/191 (21%), Positives = 70/191 (36%), Gaps = 26/191 (13%) Query: 242 LLKAGGGAGGSGG-----------SGPSAILRL---PSYRFRYRRRSRSSSRSSEPSPSR 287 L+ AGGG GG +G +A+L L + Y+ R+ S+S S+ + S Sbjct: 218 LILAGGGGGGKAAAAAAASFAAEQAGAAALLPLGAAADHHSLYKARTPSASASASSAASA 277 Query: 288 DASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAF--GGAAGGAGG 345 A+ P G A + L S G GAG +G + GA Sbjct: 278 SAALAAP-GKHLAEKKVKRVYLFGGLGTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDA 336 Query: 346 GGGGGGGAGAERDRGGASGFLTLHNAFPKEAGGGVTVTVTGPPAPPAPAPPAPSAPAPGT 405 G + A G S P + G ++ P AP+ + SA + + Sbjct: 337 PSLSGRSSAASSPAAGRS---------PADHRGYASLRAASPAPSSAPSHASSSASSHSS 387 Query: 406 LAKEAAASNTN 416 + + +S+++ Sbjct: 388 SSSSSGSSSSD 398 Score = 33.5 bits (75), Expect = 0.38 Identities = 33/125 (26%), Positives = 44/125 (35%), Gaps = 36/125 (28%) Query: 245 AGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDI 304 +GGG G GG G S+ +A GG G G + Sbjct: 161 SGGGGHGGGGGGGSS----------------------------NAGGGGGGASGGGAN-- 190 Query: 305 SMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGA-ERDRGGAS 363 S+ K S + +AG GGG A AGG GGG A + ++ GA+ Sbjct: 191 -----SKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAEQAGAA 245 Query: 364 GFLTL 368 L L Sbjct: 246 ALLPL 250 >gi|109255251 loricrin [Homo sapiens] Length = 312 Score = 58.5 bits (140), Expect = 1e-08 Identities = 44/143 (30%), Positives = 53/143 (37%), Gaps = 34/143 (23%) Query: 241 DLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFA 300 D +K GG GG GGSG GG G G + Sbjct: 15 DCVKTSGGGGGGGGSGGGGC----------------------------GFFGGGGSGGGS 46 Query: 301 STDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGA----GGGGGGGGGAGAE 356 S Y+ S G G +GGGGGG +G GG +GG+ GGGG GGG+G Sbjct: 47 SGSGCGYSGGGGYSGGGCGGG--SSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCF 104 Query: 357 RDRGGASGFLTLHNAFPKEAGGG 379 GG SG + G G Sbjct: 105 SSGGGGSGCFSSGGGGSSGGGSG 127 Score = 52.0 bits (123), Expect = 1e-06 Identities = 44/151 (29%), Positives = 59/151 (39%), Gaps = 38/151 (25%) Query: 236 CQSRSDLLKAGGGAGGSG----GSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASP 291 CQS + G GGSG G G ++ S S S Sbjct: 158 CQSYGGVSSGGSSGGGSGCFSSGGGGGSVC----------------GYSGGGSGCGGGSS 201 Query: 292 GGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAG-------GGGGGAVGAFGGAAG-GA 343 GG G +S ++ + + PS G ++G G+G GGGGG+ G GG++G G+ Sbjct: 202 GGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGS 261 Query: 344 G----------GGGGGGGGAGAERDRGGASG 364 G GGG GGG G G SG Sbjct: 262 GCIISGGGSVCGGGSSGGGGGGSSVGGSGSG 292 Score = 49.3 bits (116), Expect = 7e-06 Identities = 36/107 (33%), Positives = 42/107 (39%), Gaps = 26/107 (24%) Query: 283 PSPSRDA---SPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGA---- 335 P P D S GG GG G G G G GG GGG+ G+ Sbjct: 10 PQPPVDCVKTSGGGGGGGG----------------SGGGGCGFFGGGGSGGGSSGSGCGY 53 Query: 336 ---FGGAAGGAGGGGGGGGGAGAERDRGGASGFLTLHNAFPKEAGGG 379 G + GG GGG GGGG G GG SG ++ +GGG Sbjct: 54 SGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGG 100 Score = 48.1 bits (113), Expect = 1e-05 Identities = 37/119 (31%), Positives = 42/119 (35%), Gaps = 16/119 (13%) Query: 246 GGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDIS 305 GG GGS GSG Y S S GG GG G S Sbjct: 40 GGSGGGSSGSGCG-----------YSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSV 88 Query: 306 MYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASG 364 Y+ G + G +G GGG G F GG+ GGG G +G GG SG Sbjct: 89 KYS-----GGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSG 142 Score = 46.2 bits (108), Expect = 6e-05 Identities = 33/116 (28%), Positives = 42/116 (36%), Gaps = 20/116 (17%) Query: 240 SDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGF 299 S +GGG GGSG S S + GG GF Sbjct: 111 SGCFSSGGGGSSGGGSG-------------------CFSSGGGGSSGGGSGCFSSGGGGF 151 Query: 300 ASTDISMYTLSRDPSKGSVAAGL-AGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAG 354 + + + S GS G + GGGGG+V + G G GGG GG G+G Sbjct: 152 SGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSG 207 Score = 45.4 bits (106), Expect = 1e-04 Identities = 40/129 (31%), Positives = 51/129 (39%), Gaps = 15/129 (11%) Query: 245 AGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGG------PGGPG 298 +GGG GGSG + S F S S S S GG GG G Sbjct: 91 SGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGG 150 Query: 299 FASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERD 358 F+ + S G V++G G+ GGG G + GG G G GGG G G Sbjct: 151 FSGQAVQCQ------SYGGVSSG--GSSGGGSGCFSS-GGGGGSVCGYSGGGSGCGGGSS 201 Query: 359 RGGASGFLT 367 G SG+++ Sbjct: 202 GGSGSGYVS 210 Score = 40.4 bits (93), Expect = 0.003 Identities = 38/146 (26%), Positives = 45/146 (30%), Gaps = 32/146 (21%) Query: 246 GGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDIS 305 GGG GG GG ++ S S S S GG G F+S Sbjct: 74 GGGIGGCGGGSGGSV-------------KYSGGGGSSGGGSGCFSSGGGGSGCFSSG--- 117 Query: 306 MYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGG------------GGGGGGGA 353 S G +G GG GG G F GG G GG GG Sbjct: 118 ----GGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGG 173 Query: 354 GAERDRGGASGFLTLHNAFPKEAGGG 379 GG G + ++ GGG Sbjct: 174 SGCFSSGGGGGSVCGYSGGGSGCGGG 199 Score = 37.0 bits (84), Expect = 0.034 Identities = 42/145 (28%), Positives = 52/145 (35%), Gaps = 32/145 (22%) Query: 240 SDLLKAGGGAGGSGGSG--PSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGP 297 S +GGG GGSG S + + SS S S S GG GG Sbjct: 126 SGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGG- 184 Query: 298 GFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGA-------------FGGAA--GG 342 + Y S G G +GG G G V + +GG + GG Sbjct: 185 -----SVCGY------SGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGG 233 Query: 343 AGGGGG---GGGGAGAERDRGGASG 364 GG G GGG G+ GG+SG Sbjct: 234 GSGGSGCFSSGGGGGSSGCGGGSSG 258 >gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens] Length = 532 Score = 58.2 bits (139), Expect = 1e-08 Identities = 39/113 (34%), Positives = 49/113 (43%), Gaps = 14/113 (12%) Query: 264 PSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDISMYTLSR-DPSKGSVAAGL 322 PS ++ + SS + SE SP+ + PG S + S P+ + AA Sbjct: 405 PSSLRKHMKVHESSPQGSESSPAASSGYESSTPPGLVSPSAEPQSSSNLSPAAAAAAAAA 464 Query: 323 A-----------GAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASG 364 A G G G GGA G GG +G GGGGG GGG G GG SG Sbjct: 465 AAAAAAVSAVHRGGGSGSGGAGGGSGGGSGSGGGGGGAGGGGGG--SSGGGSG 515 Score = 54.3 bits (129), Expect = 2e-07 Identities = 33/88 (37%), Positives = 40/88 (45%), Gaps = 2/88 (2%) Query: 278 SRSSEPSPSRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFG 337 S S+EP S + SP A+ + +S G +G AG G GGG G G Sbjct: 442 SPSAEPQSSSNLSPAAAAAAAAAAAAAA--AVSAVHRGGGSGSGGAGGGSGGGSGSGGGG 499 Query: 338 GAAGGAGGGGGGGGGAGAERDRGGASGF 365 G AGG GGG GGG A G +S F Sbjct: 500 GGAGGGGGGSSGGGSGTAGGHSGLSSNF 527 >gi|51479192 ring finger protein 1 [Homo sapiens] Length = 406 Score = 57.8 bits (138), Expect = 2e-08 Identities = 47/126 (37%), Positives = 55/126 (43%), Gaps = 24/126 (19%) Query: 277 SSRSSEPSPSRDASP---GGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAV 333 + R P P D + GG G PG D +S D + S A G A GGGA Sbjct: 153 AQRVRRPIPGSDQTTTMSGGEGEPGEGEGDGE--DVSSDSAPDS-APGPAPKRPRGGGAG 209 Query: 334 GAFGGAAGGAGGGGGGGGGAGAERDRGGASGFLTLHNAFPKEAGGGVTVTVTGPPAPP-A 392 G+ G GG GG GGG G+ DRGG G TL GPP+PP A Sbjct: 210 GSSVGTGGGGTGGVGGGAGSEDSGDRGGTLGGGTL-----------------GPPSPPGA 252 Query: 393 PAPPAP 398 P+PP P Sbjct: 253 PSPPEP 258 Score = 39.3 bits (90), Expect = 0.007 Identities = 50/173 (28%), Positives = 59/173 (34%), Gaps = 41/173 (23%) Query: 246 GGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGP-------- 297 G G GG+GG G A S R + PSP SP PGG Sbjct: 214 GTGGGGTGGVGGGA----GSEDSGDRGGTLGGGTLGPPSPPGAPSPPEPGGEIELVFRPH 269 Query: 298 ------------------GFASTD-ISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGG 338 G A+ D +S Y R + GG GGGA GG Sbjct: 270 PLLVEKGEYCQTRYVKTTGNATVDHLSKYLALRIALERRQQQEAGEPGGPGGGASDT-GG 328 Query: 339 AAGGAGGGGGGGGGAGAERD-----RGGASGFLTLHNAFPKEAGGGVTVTVTG 386 G G GGG GGG G E G + T++ A GGG T+ G Sbjct: 329 PDGCGGEGGGAGGGDGPEEPALPSLEGVSEKQYTIYIA----PGGGAFTTLNG 377 >gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens] Length = 223 Score = 57.4 bits (137), Expect = 2e-08 Identities = 62/218 (28%), Positives = 96/218 (44%), Gaps = 23/218 (10%) Query: 31 AFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGASEKKDPGGLTHSGLWRI 90 +F L+ AI TD+W I +T L G G S+ + +HSGLWR Sbjct: 19 SFVLLAAAIGTDFWY-----IIDTERLERTGPGAQDLLGSINRSQPEPLS--SHSGLWRT 71 Query: 91 CCLEGLKRGVCVKI-NHFPEDTDYDHDSAEYLLRVVRASSIFPILSAILLLLGGVCVAAS 149 C ++ C + N F + +S+ LL + I LS IL++ GG+ S Sbjct: 72 CRVQS----PCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLS 127 Query: 150 RVYKSKRNIILGAGILFVAAGLSNIIGVIVYI--SANAGEPGPKRDEEK----KNHYSYG 203 + ++ ++L GILF+ + + G+ VYI SA A EEK + S+G Sbjct: 128 FLLQAYLLLLL-TGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFG 186 Query: 204 WSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRSD 241 WS G +SFI + G ++ +RE + R D Sbjct: 187 WSLALGWISFIAELLTGA----AFLAAARELSLRRRQD 220 >gi|226437592 transmembrane protein 114 [Homo sapiens] Length = 223 Score = 57.4 bits (137), Expect = 2e-08 Identities = 62/218 (28%), Positives = 96/218 (44%), Gaps = 23/218 (10%) Query: 31 AFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGASEKKDPGGLTHSGLWRI 90 +F L+ AI TD+W I +T L G G S+ + +HSGLWR Sbjct: 19 SFVLLAAAIGTDFWY-----IIDTERLERTGPGAQDLLGSINRSQPEPLS--SHSGLWRT 71 Query: 91 CCLEGLKRGVCVKI-NHFPEDTDYDHDSAEYLLRVVRASSIFPILSAILLLLGGVCVAAS 149 C ++ C + N F + +S+ LL + I LS IL++ GG+ S Sbjct: 72 CRVQS----PCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLS 127 Query: 150 RVYKSKRNIILGAGILFVAAGLSNIIGVIVYI--SANAGEPGPKRDEEK----KNHYSYG 203 + ++ ++L GILF+ + + G+ VYI SA A EEK + S+G Sbjct: 128 FLLQAYLLLLL-TGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFG 186 Query: 204 WSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRSD 241 WS G +SFI + G ++ +RE + R D Sbjct: 187 WSLALGWISFIAELLTGA----AFLAAARELSLRRRQD 220 >gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homolog isoform b [Homo sapiens] Length = 373 Score = 56.6 bits (135), Expect = 4e-08 Identities = 31/61 (50%), Positives = 33/61 (54%), Gaps = 1/61 (1%) Query: 316 GSVAAGLAGAGG-GGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASGFLTLHNAFPK 374 GS AA GAGG GGGG A GG GG GGGGGG GAG A+G L + F Sbjct: 204 GSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPHHAAGGLHFDDRFSD 263 Query: 375 E 375 E Sbjct: 264 E 264 Score = 55.8 bits (133), Expect = 7e-08 Identities = 31/62 (50%), Positives = 33/62 (53%), Gaps = 8/62 (12%) Query: 319 AAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASGFLTLHNAFPKEAGG 378 AAG A A GG G G G A+ G GGGGGGGGG G GGA LH P A G Sbjct: 202 AAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGA-----LH---PHHAAG 253 Query: 379 GV 380 G+ Sbjct: 254 GL 255 Score = 50.4 bits (119), Expect = 3e-06 Identities = 29/62 (46%), Positives = 32/62 (51%), Gaps = 7/62 (11%) Query: 320 AGLAGAGGGGGGAVGAFGGAAGG---AGGGGGGGGGAGAERDRGGASGFLTLHNAFPKEA 376 AG GA G + G GGA GG + GGGGGGGG G GA G L H+A A Sbjct: 197 AGAPGAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPHHA----A 252 Query: 377 GG 378 GG Sbjct: 253 GG 254 Score = 40.0 bits (92), Expect = 0.004 Identities = 52/199 (26%), Positives = 69/199 (34%), Gaps = 55/199 (27%) Query: 182 SANAGEPGPKRDEEKKNHYS-YGWSFYFG------GLSFILAEVIGVLAVNIY-IERSRE 233 S + P P E+K H Y W + L F + + L N + ++ + Sbjct: 70 SPSFSAPSPGSGSEQKAHLEDYYWMTGYPQQLNPEALGFSPEDAVEALISNSHQLQGGFD 129 Query: 234 AHCQSRSDLLKAGG-GAGGS-GGSGP---------SAILRL--------PSYRFRYRRRS 274 + + L A G GAG S GGSG SA++ P Y + + Sbjct: 130 GYARGAQQLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSGAGPHYHHHHHHAA 189 Query: 275 RSSSRSSEPSP----SRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGG 330 + +P S AS GG GG G G A AGGGGG Sbjct: 190 GHHHHPTAGAPGAAGSAAASAGGAGGAG--------------------GGGPASAGGGGG 229 Query: 331 GAVGAFGGAAGGAGGGGGG 349 G GG GG G GG Sbjct: 230 GG----GGGGGGGAAGAGG 244 Score = 29.3 bits (64), Expect = 7.1 Identities = 13/36 (36%), Positives = 21/36 (58%) Query: 376 AGGGVTVTVTGPPAPPAPAPPAPSAPAPGTLAKEAA 411 AGG ++ T P P P+ SAP+PG+ +++ A Sbjct: 51 AGGSLSSTPMSTPCSSVPPSPSFSAPSPGSGSEQKA 86 >gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolog isoform a [Homo sapiens] Length = 403 Score = 56.6 bits (135), Expect = 4e-08 Identities = 31/61 (50%), Positives = 33/61 (54%), Gaps = 1/61 (1%) Query: 316 GSVAAGLAGAGG-GGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASGFLTLHNAFPK 374 GS AA GAGG GGGG A GG GG GGGGGG GAG A+G L + F Sbjct: 204 GSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPHHAAGGLHFDDRFSD 263 Query: 375 E 375 E Sbjct: 264 E 264 Score = 55.8 bits (133), Expect = 7e-08 Identities = 31/62 (50%), Positives = 33/62 (53%), Gaps = 8/62 (12%) Query: 319 AAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASGFLTLHNAFPKEAGG 378 AAG A A GG G G G A+ G GGGGGGGGG G GGA LH P A G Sbjct: 202 AAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGA-----LH---PHHAAG 253 Query: 379 GV 380 G+ Sbjct: 254 GL 255 Score = 50.4 bits (119), Expect = 3e-06 Identities = 29/62 (46%), Positives = 32/62 (51%), Gaps = 7/62 (11%) Query: 320 AGLAGAGGGGGGAVGAFGGAAGG---AGGGGGGGGGAGAERDRGGASGFLTLHNAFPKEA 376 AG GA G + G GGA GG + GGGGGGGG G GA G L H+A A Sbjct: 197 AGAPGAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPHHA----A 252 Query: 377 GG 378 GG Sbjct: 253 GG 254 Score = 40.0 bits (92), Expect = 0.004 Identities = 52/199 (26%), Positives = 69/199 (34%), Gaps = 55/199 (27%) Query: 182 SANAGEPGPKRDEEKKNHYS-YGWSFYFG------GLSFILAEVIGVLAVNIY-IERSRE 233 S + P P E+K H Y W + L F + + L N + ++ + Sbjct: 70 SPSFSAPSPGSGSEQKAHLEDYYWMTGYPQQLNPEALGFSPEDAVEALISNSHQLQGGFD 129 Query: 234 AHCQSRSDLLKAGG-GAGGS-GGSGP---------SAILRL--------PSYRFRYRRRS 274 + + L A G GAG S GGSG SA++ P Y + + Sbjct: 130 GYARGAQQLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSGAGPHYHHHHHHAA 189 Query: 275 RSSSRSSEPSP----SRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGG 330 + +P S AS GG GG G G A AGGGGG Sbjct: 190 GHHHHPTAGAPGAAGSAAASAGGAGGAG--------------------GGGPASAGGGGG 229 Query: 331 GAVGAFGGAAGGAGGGGGG 349 G GG GG G GG Sbjct: 230 GG----GGGGGGGAAGAGG 244 Score = 29.3 bits (64), Expect = 7.1 Identities = 13/36 (36%), Positives = 21/36 (58%) Query: 376 AGGGVTVTVTGPPAPPAPAPPAPSAPAPGTLAKEAA 411 AGG ++ T P P P+ SAP+PG+ +++ A Sbjct: 51 AGGSLSSTPMSTPCSSVPPSPSFSAPSPGSGSEQKA 86 >gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo sapiens] Length = 2191 Score = 56.6 bits (135), Expect = 4e-08 Identities = 62/215 (28%), Positives = 80/215 (37%), Gaps = 54/215 (25%) Query: 253 GGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASP-----GGPGGPGF-----AST 302 GG GP+A+ +Y S+ + P A P GG PG AS Sbjct: 162 GGGGPAAVPEFNNYY--------GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASA 213 Query: 303 DISMYTLSRDPSKGSVAA------------GLAGAGGGGGGAVGAFGGAAGGAGGGGGGG 350 + S DP + S GAGGGGGG G GG+ GG GGGG G Sbjct: 214 AAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGA 273 Query: 351 GGAG------------AERDRGGASGFLTLHNAF-----PKEAGGGVTVTVTGPPAPPAP 393 GGAG A GG G+ + P++ GGG+ + G A A Sbjct: 274 GGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGA--AS 331 Query: 394 APPAPSAPAPGTLAKEAAASN-----TNTLNRKTT 423 A + A G + A + T TLN+ T Sbjct: 332 LSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLT 366 Score = 36.2 bits (82), Expect = 0.058 Identities = 36/156 (23%), Positives = 59/156 (37%), Gaps = 7/156 (4%) Query: 229 ERSREAHCQSRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRD 288 ++ ++ Q + + GG+GG P + + + S + ++ P P Sbjct: 62 QQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLL 121 Query: 289 ASPGGPGG--PGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAV----GAFGGAAGG 342 + PG P Y + G+ +A GGGGG A + G+A Sbjct: 122 SKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAP 181 Query: 343 AGGGGGGGGGAGAERDRGGAS-GFLTLHNAFPKEAG 377 A GG GG G ++ G S G +H+A AG Sbjct: 182 ASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAG 217 >gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo sapiens] Length = 2231 Score = 56.6 bits (135), Expect = 4e-08 Identities = 62/215 (28%), Positives = 80/215 (37%), Gaps = 54/215 (25%) Query: 253 GGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASP-----GGPGGPGF-----AST 302 GG GP+A+ +Y S+ + P A P GG PG AS Sbjct: 162 GGGGPAAVPEFNNYY--------GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASA 213 Query: 303 DISMYTLSRDPSKGSVAA------------GLAGAGGGGGGAVGAFGGAAGGAGGGGGGG 350 + S DP + S GAGGGGGG G GG+ GG GGGG G Sbjct: 214 AAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGA 273 Query: 351 GGAG------------AERDRGGASGFLTLHNAF-----PKEAGGGVTVTVTGPPAPPAP 393 GGAG A GG G+ + P++ GGG+ + G A A Sbjct: 274 GGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGA--AS 331 Query: 394 APPAPSAPAPGTLAKEAAASN-----TNTLNRKTT 423 A + A G + A + T TLN+ T Sbjct: 332 LSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLT 366 Score = 36.2 bits (82), Expect = 0.058 Identities = 36/156 (23%), Positives = 59/156 (37%), Gaps = 7/156 (4%) Query: 229 ERSREAHCQSRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRD 288 ++ ++ Q + + GG+GG P + + + S + ++ P P Sbjct: 62 QQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLL 121 Query: 289 ASPGGPGG--PGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAV----GAFGGAAGG 342 + PG P Y + G+ +A GGGGG A + G+A Sbjct: 122 SKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAP 181 Query: 343 AGGGGGGGGGAGAERDRGGAS-GFLTLHNAFPKEAG 377 A GG GG G ++ G S G +H+A AG Sbjct: 182 ASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAG 217 >gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo sapiens] Length = 2178 Score = 56.6 bits (135), Expect = 4e-08 Identities = 62/215 (28%), Positives = 80/215 (37%), Gaps = 54/215 (25%) Query: 253 GGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASP-----GGPGGPGF-----AST 302 GG GP+A+ +Y S+ + P A P GG PG AS Sbjct: 162 GGGGPAAVPEFNNYY--------GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASA 213 Query: 303 DISMYTLSRDPSKGSVAA------------GLAGAGGGGGGAVGAFGGAAGGAGGGGGGG 350 + S DP + S GAGGGGGG G GG+ GG GGGG G Sbjct: 214 AAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGA 273 Query: 351 GGAG------------AERDRGGASGFLTLHNAF-----PKEAGGGVTVTVTGPPAPPAP 393 GGAG A GG G+ + P++ GGG+ + G A A Sbjct: 274 GGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGA--AS 331 Query: 394 APPAPSAPAPGTLAKEAAASN-----TNTLNRKTT 423 A + A G + A + T TLN+ T Sbjct: 332 LSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLT 366 Score = 36.2 bits (82), Expect = 0.058 Identities = 36/156 (23%), Positives = 59/156 (37%), Gaps = 7/156 (4%) Query: 229 ERSREAHCQSRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRD 288 ++ ++ Q + + GG+GG P + + + S + ++ P P Sbjct: 62 QQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLL 121 Query: 289 ASPGGPGG--PGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAV----GAFGGAAGG 342 + PG P Y + G+ +A GGGGG A + G+A Sbjct: 122 SKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAP 181 Query: 343 AGGGGGGGGGAGAERDRGGAS-GFLTLHNAFPKEAG 377 A GG GG G ++ G S G +H+A AG Sbjct: 182 ASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAG 217 >gi|195972866 keratin 10 [Homo sapiens] Length = 584 Score = 56.2 bits (134), Expect = 5e-08 Identities = 49/144 (34%), Positives = 59/144 (40%), Gaps = 14/144 (9%) Query: 231 SREAHCQSRSDLLKAGGGAGGSGGSGPSAILRLPSYR------FRYRRRSRSS-SRSSEP 283 S + + SRS GGG GG GG G + LR+ S + F S S SR S Sbjct: 7 SSKHYSSSRSG---GGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSG 63 Query: 284 SPSRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGA 343 S GG GG G + S G+ GGG G+FGG + G Sbjct: 64 GGCFGGSSGGYGGLG----GFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGG 119 Query: 344 GGGGGGGGGAGAERDRGGASGFLT 367 GG GGGG G G GG G L+ Sbjct: 120 GGFGGGGFGGGFGGGFGGDGGLLS 143 Score = 55.5 bits (132), Expect = 9e-08 Identities = 40/132 (30%), Positives = 51/132 (38%), Gaps = 16/132 (12%) Query: 233 EAHCQSRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPG 292 E Q+ LL+ G +GG G G S + Y SS G Sbjct: 443 ENEIQTYRSLLEGEGSSGGGGRGGGS-------FGGGY---GGGSSGGGSSGGGHGGGHG 492 Query: 293 GPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGG 352 G G G+ S S G G + +GG GG + G +GG + G GGGG GGG Sbjct: 493 GSSGGGYGGGS------SGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGS 546 Query: 353 AGAERDRGGASG 364 +G GG G Sbjct: 547 SGGGSSSGGGYG 558 Score = 47.0 bits (110), Expect = 3e-05 Identities = 35/94 (37%), Positives = 43/94 (45%), Gaps = 11/94 (11%) Query: 278 SRSSEPSPSRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGG------ 331 S S S SR GG GG G + +L SKGS+ G + G GG Sbjct: 6 SSSKHYSSSRSGGGGGGGGCGGGG---GVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSS 62 Query: 332 AVGAFGGAAGGAGGGGGGGGGAGAERDRGGASGF 365 G FGG++GG GG G G G G+ R G+S F Sbjct: 63 GGGCFGGSSGGYGGLG--GFGGGSFRGSYGSSSF 94 Score = 47.0 bits (110), Expect = 3e-05 Identities = 34/119 (28%), Positives = 44/119 (36%), Gaps = 20/119 (16%) Query: 246 GGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDIS 305 GGG+ G G SG SS +S GG G G+ Sbjct: 474 GGGSSGGGSSGGG--------------HGGGHGGSSGGGYGGGSSGGGSSGGGYGGGS-- 517 Query: 306 MYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASG 364 S GS + G G GGGG G + GG+ GGG GGG+ + + +SG Sbjct: 518 ----SSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSG 572 Score = 46.6 bits (109), Expect = 4e-05 Identities = 22/64 (34%), Positives = 28/64 (43%) Query: 316 GSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASGFLTLHNAFPKE 375 GS G G GGG + G +GG + G GG GG G GG G+ + Sbjct: 493 GSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSS 552 Query: 376 AGGG 379 +GGG Sbjct: 553 SGGG 556 Score = 45.8 bits (107), Expect = 7e-05 Identities = 36/119 (30%), Positives = 42/119 (35%), Gaps = 31/119 (26%) Query: 246 GGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDIS 305 GGG GGS G G S SS +S GG GG Sbjct: 488 GGGHGGSSGGGYGG--------------GSSGGGSSGGGYGGGSSSGGHGGS-------- 525 Query: 306 MYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASG 364 S G G +G GGGG G G+ GG + GG GGG G + G+ G Sbjct: 526 --------SSGGYGGGSSGGGGGGYGG-GSSGGGSSSGGGYGGGSSSGGHKSSSSGSVG 575 Score = 38.1 bits (87), Expect = 0.015 Identities = 21/60 (35%), Positives = 27/60 (45%), Gaps = 2/60 (3%) Query: 307 YTLSRDPSKGSVAAGLAGAGGGGGGAVGA--FGGAAGGAGGGGGGGGGAGAERDRGGASG 364 Y+ S+ S G G G GGGG V + + G GGG GG +G RG + G Sbjct: 5 YSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGG 64 >gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo sapiens] Length = 217 Score = 55.8 bits (133), Expect = 7e-08 Identities = 61/218 (27%), Positives = 96/218 (44%), Gaps = 23/218 (10%) Query: 31 AFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGASEKKDPGGLTHSGLWRI 90 +F L+ AI T++W I +T L G G S+ + +HSGLWR Sbjct: 13 SFVLLAAAIGTEFWY-----IIDTERLERTGPGAQDLLGSINRSQPEPLS--SHSGLWRT 65 Query: 91 CCLEGLKRGVCVKI-NHFPEDTDYDHDSAEYLLRVVRASSIFPILSAILLLLGGVCVAAS 149 C ++ C + N F + +S+ LL + I LS IL++ GG+ S Sbjct: 66 CRVQS----PCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLS 121 Query: 150 RVYKSKRNIILGAGILFVAAGLSNIIGVIVYI--SANAGEPGPKRDEEK----KNHYSYG 203 + ++ ++L GILF+ + + G+ VYI SA A EEK + S+G Sbjct: 122 FLLQAYLLLLL-TGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFG 180 Query: 204 WSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRSD 241 WS G +SFI + G ++ +RE + R D Sbjct: 181 WSLALGWISFIAELLTGA----AFLAAARELSLRRRQD 214 >gi|33620755 YEATS domain containing 2 [Homo sapiens] Length = 1422 Score = 55.8 bits (133), Expect = 7e-08 Identities = 49/161 (30%), Positives = 72/161 (44%), Gaps = 17/161 (10%) Query: 238 SRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGG---- 293 +++ + AG GS GS A L+LP+ ++ + S++ S G Sbjct: 718 TKAQVTAAGPQKSGSQGS-VMATLQLPATNLANLANLPPGTKLYLTTNSKNPSGKGKLLL 776 Query: 294 -PGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGG---AGGGGGG 349 P G +T+ + + GS A+G +GAGGGGGG G G+ GG GGGG Sbjct: 777 IPQGAILRATN------NANLQSGSAASGGSGAGGGGGGGGGGGSGSGGGGSTGGGGGTA 830 Query: 350 GGGAGAERDRGGASGFLTLHNAFPKEAGGGVTVTVTGPPAP 390 GGG + GG S LT + K+ G + G P+P Sbjct: 831 GGGTQSTAGPGGISQHLTYTSYILKQTPQG--TFLVGQPSP 869 >gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens] Length = 332 Score = 55.5 bits (132), Expect = 9e-08 Identities = 27/41 (65%), Positives = 28/41 (68%) Query: 316 GSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAE 356 G+ A G GAGGG GG GA GG AGGAGGGGGGG A E Sbjct: 35 GNGAGGGGGAGGGSGGGNGAGGGGAGGAGGGGGGGSRAPPE 75 Score = 49.7 bits (117), Expect = 5e-06 Identities = 25/53 (47%), Positives = 28/53 (52%), Gaps = 4/53 (7%) Query: 312 DPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASG 364 D S+ +G G G GG GA GG+ GG G GGGG GGAG GG G Sbjct: 21 DSHHRSILLASSGGGNGAGGGGGAGGGSGGGNGAGGGGAGGAGG----GGGGG 69 Score = 47.4 bits (111), Expect = 3e-05 Identities = 23/40 (57%), Positives = 25/40 (62%), Gaps = 1/40 (2%) Query: 319 AAGLAGAGGGGGGAVGAFGG-AAGGAGGGGGGGGGAGAER 357 + G GAGGGGG G+ GG AGG G GG GGGG G R Sbjct: 32 SGGGNGAGGGGGAGGGSGGGNGAGGGGAGGAGGGGGGGSR 71 Score = 44.7 bits (104), Expect = 2e-04 Identities = 20/41 (48%), Positives = 22/41 (53%) Query: 319 AAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDR 359 ++G GGGGGA G GG G GGG GG GG G R Sbjct: 31 SSGGGNGAGGGGGAGGGSGGGNGAGGGGAGGAGGGGGGGSR 71 Score = 43.9 bits (102), Expect = 3e-04 Identities = 22/41 (53%), Positives = 23/41 (56%), Gaps = 2/41 (4%) Query: 325 AGGGGGGAVGAFGGAAGGAGGG--GGGGGGAGAERDRGGAS 363 A GGG G GGA GG+GGG GGGG GA GG S Sbjct: 30 ASSGGGNGAGGGGGAGGGSGGGNGAGGGGAGGAGGGGGGGS 70 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.137 0.417 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,340,241 Number of Sequences: 37866 Number of extensions: 1285739 Number of successful extensions: 43721 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 811 Number of HSP's successfully gapped in prelim test: 797 Number of HSP's that attempted gapping in prelim test: 15823 Number of HSP's gapped (non-prelim): 12954 length of query: 425 length of database: 18,247,518 effective HSP length: 105 effective length of query: 320 effective length of database: 14,271,588 effective search space: 4566908160 effective search space used: 4566908160 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.