Guide to the Human Genome
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Search of human proteins with 222352129

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|222352129 von Willebrand factor A domain containing 5B2
[Homo sapiens]
         (1242 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|222352129 von Willebrand factor A domain containing 5B2 [Homo...  2560   0.0  
gi|210147462 von Willebrand factor A domain containing 5B1 [Homo...   531   e-150
gi|194306644 BCSC-1 isoform 1 [Homo sapiens]                          142   3e-33
gi|38195080 BCSC-1 isoform 1 [Homo sapiens]                           142   3e-33
gi|38195082 BCSC-1 isoform 2 [Homo sapiens]                            89   3e-17
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    67   8e-11
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    62   3e-09
gi|163965366 nascent polypeptide-associated complex alpha subuni...    57   1e-07
gi|205277425 immunoglobulin superfamily, member 9 isoform a [Hom...    56   2e-07
gi|205277423 immunoglobulin superfamily, member 9 isoform b [Hom...    56   2e-07
gi|149158690 HLA-B associated transcript-2 [Homo sapiens]              54   9e-07
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     53   2e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    52   3e-06
gi|237757312 synaptojanin 1 isoform c [Homo sapiens]                   51   8e-06
gi|20143482 melanoma antigen family E, 1 [Homo sapiens]                50   1e-05
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]               50   1e-05
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p...    50   2e-05
gi|41281612 zinc finger protein 828 [Homo sapiens]                     49   4e-05
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    48   5e-05
gi|27735129 hypothetical protein LOC148345 [Homo sapiens]              48   7e-05
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                48   7e-05
gi|237757310 synaptojanin 1 isoform a [Homo sapiens]                   47   9e-05
gi|237757308 synaptojanin 1 isoform b [Homo sapiens]                   47   9e-05
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom...    47   9e-05
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom...    47   9e-05
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap...    47   9e-05
gi|237757326 synaptojanin 1 isoform d [Homo sapiens]                   47   9e-05
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]        47   9e-05
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        47   9e-05
gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo...    47   1e-04

>gi|222352129 von Willebrand factor A domain containing 5B2 [Homo
            sapiens]
          Length = 1242

 Score = 2560 bits (6636), Expect = 0.0
 Identities = 1242/1242 (100%), Positives = 1242/1242 (100%)

Query: 1    MPGLYCPSSWTPLPLTDSWVRACANGPCLSVRARLTYRNPQPQPVDGVFVYPLAEAEVVS 60
            MPGLYCPSSWTPLPLTDSWVRACANGPCLSVRARLTYRNPQPQPVDGVFVYPLAEAEVVS
Sbjct: 1    MPGLYCPSSWTPLPLTDSWVRACANGPCLSVRARLTYRNPQPQPVDGVFVYPLAEAEVVS 60

Query: 61   GFEAEAAGRRVSFQLQSRRRSQAACCRALGPGLGTPTPRRCAQGHLVLDLAQARSTLVLP 120
            GFEAEAAGRRVSFQLQSRRRSQAACCRALGPGLGTPTPRRCAQGHLVLDLAQARSTLVLP
Sbjct: 61   GFEAEAAGRRVSFQLQSRRRSQAACCRALGPGLGTPTPRRCAQGHLVLDLAQARSTLVLP 120

Query: 121  TGIIAAAGTMTVTLHSSRELPSRPDGVLHVALPTVLTPLAPPGPPGPPRPPGLCDDSPTS 180
            TGIIAAAGTMTVTLHSSRELPSRPDGVLHVALPTVLTPLAPPGPPGPPRPPGLCDDSPTS
Sbjct: 121  TGIIAAAGTMTVTLHSSRELPSRPDGVLHVALPTVLTPLAPPGPPGPPRPPGLCDDSPTS 180

Query: 181  CFGVGSLQEEGLAWEELAAPRDVFSGPARCPAPYTFSFEMLVTGPCLLAGLESPSHALRA 240
            CFGVGSLQEEGLAWEELAAPRDVFSGPARCPAPYTFSFEMLVTGPCLLAGLESPSHALRA
Sbjct: 181  CFGVGSLQEEGLAWEELAAPRDVFSGPARCPAPYTFSFEMLVTGPCLLAGLESPSHALRA 240

Query: 241  DAPPHASSAATICVTLAEGHHCDRALEILLHPSEPHQPHLMLEGGSLSSAEYEARVRARR 300
            DAPPHASSAATICVTLAEGHHCDRALEILLHPSEPHQPHLMLEGGSLSSAEYEARVRARR
Sbjct: 241  DAPPHASSAATICVTLAEGHHCDRALEILLHPSEPHQPHLMLEGGSLSSAEYEARVRARR 300

Query: 301  DFQRLQRRDSDGDRQVWFLQRRFHKDILLNPVLALSFCPDLSSKPGHLGTATRELLFLLD 360
            DFQRLQRRDSDGDRQVWFLQRRFHKDILLNPVLALSFCPDLSSKPGHLGTATRELLFLLD
Sbjct: 301  DFQRLQRRDSDGDRQVWFLQRRFHKDILLNPVLALSFCPDLSSKPGHLGTATRELLFLLD 360

Query: 361  SSSVAHKDAIVLAVKSLPPQTLINLAVFGTLVQPLFPESRPCSDDAVQLICESIETLQVP 420
            SSSVAHKDAIVLAVKSLPPQTLINLAVFGTLVQPLFPESRPCSDDAVQLICESIETLQVP
Sbjct: 361  SSSVAHKDAIVLAVKSLPPQTLINLAVFGTLVQPLFPESRPCSDDAVQLICESIETLQVP 420

Query: 421  SGPPDVLAALDWAVGQPQHRAYPRQLFLLTAASPMAATTHRTLELMRWHRGTARCFSFGL 480
            SGPPDVLAALDWAVGQPQHRAYPRQLFLLTAASPMAATTHRTLELMRWHRGTARCFSFGL
Sbjct: 421  SGPPDVLAALDWAVGQPQHRAYPRQLFLLTAASPMAATTHRTLELMRWHRGTARCFSFGL 480

Query: 481  GPTCHQLLQGLSALSRGQAYFLRPGQRLQPMLVQALRKALEPALSDISVDWFVPDTVEAL 540
            GPTCHQLLQGLSALSRGQAYFLRPGQRLQPMLVQALRKALEPALSDISVDWFVPDTVEAL
Sbjct: 481  GPTCHQLLQGLSALSRGQAYFLRPGQRLQPMLVQALRKALEPALSDISVDWFVPDTVEAL 540

Query: 541  LTPREIPALYPGDQLLGYCSLFRVDGFRSRPPGGQEPGWQSSGGSVFPSPEEAPSAASPG 600
            LTPREIPALYPGDQLLGYCSLFRVDGFRSRPPGGQEPGWQSSGGSVFPSPEEAPSAASPG
Sbjct: 541  LTPREIPALYPGDQLLGYCSLFRVDGFRSRPPGGQEPGWQSSGGSVFPSPEEAPSAASPG 600

Query: 601  TEPTGTSEPLGTGTVSAELSSPWAARDSEQSTDALTDPVTDPGPNPSDTAIWRRIFQSSY 660
            TEPTGTSEPLGTGTVSAELSSPWAARDSEQSTDALTDPVTDPGPNPSDTAIWRRIFQSSY
Sbjct: 601  TEPTGTSEPLGTGTVSAELSSPWAARDSEQSTDALTDPVTDPGPNPSDTAIWRRIFQSSY 660

Query: 661  IREQYVLTHCSASPEPGPGSTGSSESPGSQGPGSPEGSAPLEPPSQQGCRSLAWGEPAGS 720
            IREQYVLTHCSASPEPGPGSTGSSESPGSQGPGSPEGSAPLEPPSQQGCRSLAWGEPAGS
Sbjct: 661  IREQYVLTHCSASPEPGPGSTGSSESPGSQGPGSPEGSAPLEPPSQQGCRSLAWGEPAGS 720

Query: 721  RSCPLPAPTPAPFKVGALSTEVLGRQHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILD 780
            RSCPLPAPTPAPFKVGALSTEVLGRQHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILD
Sbjct: 721  RSCPLPAPTPAPFKVGALSTEVLGRQHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILD 780

Query: 781  GPSPEPGQQLGQGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVPPQAPRCH 840
            GPSPEPGQQLGQGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVPPQAPRCH
Sbjct: 781  GPSPEPGQQLGQGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVPPQAPRCH 840

Query: 841  VVIRGLCGEQPMCWEVGVGLETLWGPGDGSQPPSPPVREAAWDQALHRLTAASVVRDNEQ 900
            VVIRGLCGEQPMCWEVGVGLETLWGPGDGSQPPSPPVREAAWDQALHRLTAASVVRDNEQ
Sbjct: 841  VVIRGLCGEQPMCWEVGVGLETLWGPGDGSQPPSPPVREAAWDQALHRLTAASVVRDNEQ 900

Query: 901  LALRGGAETTADRGHARRCWLRALQTSKVSSAPSCFTCPVAVDATTREVLPGALQVCSSE 960
            LALRGGAETTADRGHARRCWLRALQTSKVSSAPSCFTCPVAVDATTREVLPGALQVCSSE
Sbjct: 901  LALRGGAETTADRGHARRCWLRALQTSKVSSAPSCFTCPVAVDATTREVLPGALQVCSSE 960

Query: 961  PAEPPGTPPASHSHLDAAPLPTVVYSKGLQRGSPAGAWDSDQNGNSKRALGDPATPTEGP 1020
            PAEPPGTPPASHSHLDAAPLPTVVYSKGLQRGSPAGAWDSDQNGNSKRALGDPATPTEGP
Sbjct: 961  PAEPPGTPPASHSHLDAAPLPTVVYSKGLQRGSPAGAWDSDQNGNSKRALGDPATPTEGP 1020

Query: 1021 RRPPPRPPCRLSMGRRHKLCSPDPGQANNSEGSDHDYLPLVRLQEAPGSFRLDAPFCAAV 1080
            RRPPPRPPCRLSMGRRHKLCSPDPGQANNSEGSDHDYLPLVRLQEAPGSFRLDAPFCAAV
Sbjct: 1021 RRPPPRPPCRLSMGRRHKLCSPDPGQANNSEGSDHDYLPLVRLQEAPGSFRLDAPFCAAV 1080

Query: 1081 RISQERLCRASPFAVHRASLSPTSASLPWALLGPGVGQGDSATASCSPSPSSGSEGPGQV 1140
            RISQERLCRASPFAVHRASLSPTSASLPWALLGPGVGQGDSATASCSPSPSSGSEGPGQV
Sbjct: 1081 RISQERLCRASPFAVHRASLSPTSASLPWALLGPGVGQGDSATASCSPSPSSGSEGPGQV 1140

Query: 1141 DSGRGSDTEASEGAEGLGGTDLRGRTWATAVALAWLEHRCAAAFDEWELTAAKADCWLRA 1200
            DSGRGSDTEASEGAEGLGGTDLRGRTWATAVALAWLEHRCAAAFDEWELTAAKADCWLRA
Sbjct: 1141 DSGRGSDTEASEGAEGLGGTDLRGRTWATAVALAWLEHRCAAAFDEWELTAAKADCWLRA 1200

Query: 1201 QHLPDGLDLAALKAAARGLFLLLRHWDQNLQLHLLCYSPANV 1242
            QHLPDGLDLAALKAAARGLFLLLRHWDQNLQLHLLCYSPANV
Sbjct: 1201 QHLPDGLDLAALKAAARGLFLLLRHWDQNLQLHLLCYSPANV 1242


>gi|210147462 von Willebrand factor A domain containing 5B1 [Homo
            sapiens]
          Length = 1215

 Score =  531 bits (1368), Expect = e-150
 Identities = 414/1315 (31%), Positives = 612/1315 (46%), Gaps = 179/1315 (13%)

Query: 1    MPGLYCPSSWTPLPLTDSWVRACANGPCLSVRARLTYRNPQPQPVDGVFVYPLAEAEVVS 60
            MPGL    +   LPLT S V +C +G  L + A LTY N + QP  G+FVYPL E   V 
Sbjct: 1    MPGLLNWITGAALPLTASDVTSCVSGYALGLTASLTYGNLEAQPFQGLFVYPLDECTTVI 60

Query: 61   GFEAEAAGRRVSFQLQSRR------------RSQAACCRALGPGLGTPTPRRCAQGHLVL 108
            GFEA  A R V+ Q++ +             RS       L  G+    P  C  G + L
Sbjct: 61   GFEAVIADRVVTVQIKDKAKLESGHFDASHVRSPTVTGNILQDGVSI-APHSCTPGKVTL 119

Query: 109  DLAQARSTLVLPTGIIAAAGTMTVTLHSSRELPSRPDGVLHVALPTVLTPLAPP---GPP 165
            D    R   V   G IA    +T+ + +S ELP+ P G + V LP V  P  P       
Sbjct: 120  DEDLERILFVANLGTIAPMENVTIFISTSSELPTLPSGAVRVLLPAVCAPTVPQFCTKST 179

Query: 166  GPPRPPGLCDDSPTSCFGVGSLQEEGLAWEELAAPRDVFSGPARCPAPYTFSFEMLVTGP 225
            G         D    CFG  +      +W +L     + +     P  Y F+F++ + GP
Sbjct: 180  GTSNQQAQGKDR--HCFGAWAPG----SWNKLCLAT-LLNTEVSNPMEYEFNFQLEIRGP 232

Query: 226  CLLAGLESPSHALRADAPPHASSAATICVTLAEGHHCDRALEILLHPSEPHQPHLMLEGG 285
            CLLAG+ESP+H +RADA P A SA +I +TLA  H  DR +EIL+HPSEPH PH+++E G
Sbjct: 233  CLLAGVESPTHEIRADAAPSARSAKSIIITLANKHTFDRPVEILIHPSEPHMPHVLIEKG 292

Query: 286  SLSSAEYEARVRARRDFQRLQRRDSDGDRQVWFLQRRFHKDILLNPVLALSFCPDLSSKP 345
             ++  E++  ++ R DF +  ++ S  +R+   +++R HKDI  + V+ L+FCPDL S  
Sbjct: 293  DMTLGEFDQHLKGRTDFIKGMKKKSRAERKTEIIRKRLHKDIPHHSVIMLNFCPDLQSVQ 352

Query: 346  GHLGTATRELLFLLDSSSVAH-------KDAIVLAVKSLPPQTLINLAVFGTLVQPLFPE 398
              L  A  E +FL+D SS          KDA+++A+KSL P  L N+  FG+  + LFP 
Sbjct: 353  PCLRKAHGEFIFLIDRSSSMSGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPS 412

Query: 399  SRPCSDDAVQLICESIETLQVPSGPPDVLAALDWAVGQPQHRAYPRQLFLLTAASPMAAT 458
            S+  S+D++ + C+ I+ ++   G  ++L+ L W + QP HR +PR LF++T  +     
Sbjct: 413  SQTYSEDSLAMACDDIQRMKADMGGTNILSPLKWVIRQPVHRGHPRLLFVITDGA--VNN 470

Query: 459  THRTLELMRWHRGTARCFSFGLGP-TCHQLLQGLSALSRGQAYFLRPGQRLQPMLVQALR 517
            T + LEL+R H  + RC+SFG+GP  CH+L++GL+++S G A  L  G+RLQP +V++L+
Sbjct: 471  TGKVLELVRNHAFSTRCYSFGIGPNVCHRLVKGLASVSEGSAELLMEGERLQPKMVKSLK 530

Query: 518  KALEPALSDISVDWFVPDTVEALLTPREIPALYPGDQLLGYCSLFRVDGFRSRPPGGQEP 577
            KA+ P LSD++V+W  P+T E L++P    +L+PG++L+GY  +       S P   +  
Sbjct: 531  KAMAPVLSDVTVEWIFPETTEVLVSPVSASSLFPGERLVGYGIVCDASLHISNPRSDKRR 590

Query: 578  GW-----QSSGGSVFPSPEE----------APSAASPGTEPTGTSEPLGTGTVSAELSSP 622
             +     Q SG SVF   ++          A ++ +P       +  L +G  + +    
Sbjct: 591  RYSMLHSQESGSSVFYHSQDDGPGLEGGDCAKNSGAPFILGQAKNARLASGDSTTKHDLN 650

Query: 623  WAARDSEQSTDALTD--------PVTDPGPNPSDTAIWRRIFQSSYIREQYVLTHCSASP 674
             + R    ST+ +T+          +DP P      + +   Q    +    +       
Sbjct: 651  LSQRRRAYSTNQITNHKPLPRATMASDPMPAAKRYPLRKARLQDLTNQTSLDVQRWQIDL 710

Query: 675  EPGPGS-TGSSESPGSQGPGSPEGSAPLEPPSQQGCRS-LAWGEPAGSRSCPLPAPTPAP 732
            +P   S    ++ P  +GPG+   S  L P   QGC+  L WG+   + S P+   T   
Sbjct: 711  QPLLNSGQDLNQGPKLRGPGARRPS--LLP---QGCQPFLPWGQETQAWS-PVRERTSDS 764

Query: 733  FKVGALSTEVLGRQHRAALAGRSLSS-PPGRANQVPGRPRKPSLGAILDGPSPEPGQQLG 791
               G L        H +A    + S   P   +Q    P +P+       P+P  G+ L 
Sbjct: 765  RSPGDLEPS----HHPSAFETETSSDWDPPAESQERASPSRPAT------PAPVLGKALV 814

Query: 792  QGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVPPQAPRCHVVIRGLCGEQP 851
            +GL DS  L       W++             S EL  P                     
Sbjct: 815  KGLHDSQRL------QWEV-------------SFELGTP--------------------- 834

Query: 852  MCWEVGVGLETLWGPGDGSQPPSPPVREAAWDQALHRLTAASVVRDNEQLALRGGAETTA 911
                         GP  G    +       W +  H L A +++RD EQLA R G     
Sbjct: 835  -------------GPERGGAQDAD-----LWSETFHHLAARAIIRDFEQLAEREG---EI 873

Query: 912  DRGHARRCWLRALQTSKVSSAPSCFTCPVAVDATTREVLPGALQVCSSEPA--------- 962
            ++G  RR  + AL TSK  +  S +T  V VD +    LP  ++  +S  A         
Sbjct: 874  EQGSNRRYQVSALHTSKACNIISKYTAFVPVDVSKSRYLPTVVEYPNSGAALRMLGSRAL 933

Query: 963  --EPPGTP-----PASHSHLDAAP------LPTVVYSKGLQRG-SPAGAWDSDQNGNSKR 1008
              +  GT      P +    D+AP       PT ++S+    G    GA +  Q   +  
Sbjct: 934  AQQWRGTSSGFGRPQTMLGEDSAPGNDMEASPTALFSEARSPGREKHGASEGPQRSLATN 993

Query: 1009 ALGD-PATPTEGPRRPPPRPPCRLSMGRRHKLCSPDPGQANNSEGS-DHDYLPLVRLQEA 1066
             L    A+               L+   +  L  P      ++ G+   DY+PLV LQ A
Sbjct: 994  TLSSMKASENLFGSWLNLNKSRLLTRAAKGFLSKPLIKAVESTSGNQSFDYIPLVSLQLA 1053

Query: 1067 PGSFRLDAPFCAAVRISQERLCRASPFAVHRASLS--PTSASLPWALLGPGVGQGDSATA 1124
             G+F L+  FC A  I  E+L   SPF  HR SL+  P+ +  P   L          T+
Sbjct: 1054 SGAFLLNEAFCEATHIPMEKLKWTSPFTCHRVSLTTRPSESKTPSPQL---------CTS 1104

Query: 1125 SCSPSPSSGSEGPGQVDSGRGSDTEASEGAEGLGGTDLRGRTWATAVALAWLEHRCAAAF 1184
            S    PS  S     +  G+        G E     +  G+ WAT V LAWLEH  A+ F
Sbjct: 1105 SPPRHPSCDSFSLEPLAKGK-------LGLEPRAVVEHTGKLWATVVGLAWLEHSSASYF 1157

Query: 1185 DEWELTAAKADCWLRAQHLPDGLDLAALKAAARGLFLLLRHWDQNLQLHLLCYSP 1239
             EWEL AAKA+ WL  Q +P+G     LKAAAR LF+LLRHWD+NL+ ++LCY+P
Sbjct: 1158 TEWELVAAKANSWLEQQEVPEGRTQGTLKAAARQLFVLLRHWDENLEFNMLCYNP 1212


>gi|194306644 BCSC-1 isoform 1 [Homo sapiens]
          Length = 786

 Score =  142 bits (357), Expect = 3e-33
 Identities = 133/568 (23%), Positives = 228/568 (40%), Gaps = 96/568 (16%)

Query: 12  PLPLTDSWVRACANGPCLSVRARLTYRNPQPQPVDGVFVYPLAEAEVVSGFEAEAAGRRV 71
           P+PL    V          V A L Y N +  P++  FV+P+ E   V  FEA   G+++
Sbjct: 14  PVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKI 73

Query: 72  SFQLQSRRRSQAACCRALGPGLGTPTPRRCAQGHLVLDLAQARSTLVLPTGIIAAAGTMT 131
             +LQ + +++    +A+  G          Q  L+   + +R       G +       
Sbjct: 74  VAELQDKMKARTNYEKAISQG---------HQAFLLEGDSSSRDVFSCNVGNLQPGSKAA 124

Query: 132 VTLHSSRELPSRPDGVLHVALPTVLTPLAPPGPPGPPRPPGLCDDSPTSCFGVGSLQEEG 191
           VTL   +ELP   DG L   LP VL P                  S  SC  V +     
Sbjct: 125 VTLKYVQELPLEADGALRFVLPAVLNPRYQ-----------FSGSSKDSCLNVKT----- 168

Query: 192 LAWEELAAPRDVFSGPARCPAPYTFSFEMLVTGPCLLAGLESPSHALRADAPPHASSAAT 251
                +    D+         PYT S    +     +  ++S       +      ++A 
Sbjct: 169 ----PIVPVEDL---------PYTLSMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQ 215

Query: 252 ICVTLAEGHHCDRALEILLHPSEPHQPHLMLEGGSLSSAEYEARVRARRDFQRLQRRDSD 311
             V+LA GH  DR +E+L++ +E H P ++LE G                          
Sbjct: 216 --VSLAAGHKFDRDVELLIYYNEVHTPSVVLEMG-------------------------- 247

Query: 312 GDRQVWFLQRRFHKDILLNPVLALSFCPDL-SSKPGHLGTATRELLFLLDSSSV------ 364
                  +       ++ +P   +SF P++   +P +      E +FL+D S        
Sbjct: 248 -------MPNMKPGHLMGDPSAMVSFYPNIPEDQPSN---TCGEFIFLMDRSGSMQSPMS 297

Query: 365 ----------AHKDAIVLAVKSLPPQTLINLAVFGTLVQPLFPESRPCSDDAVQLICESI 414
                     A K+ ++L +KSLP     N+  FG+  +  FPES   +   ++     +
Sbjct: 298 SQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRV 357

Query: 415 ETLQVPSGPPDVLAALDWAVGQPQHRAYPRQLFLLTAASPMAATTHRTLELMRWHRGTAR 474
           + +Q   G  ++LA L      P    +P QLF+ T        T   ++ +R +R   R
Sbjct: 358 KLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGE--VTDTFSVIKEVRINRQKHR 415

Query: 475 CFSFGLGP-TCHQLLQGLSALSRGQAYFLRPGQRLQPMLVQALRKALEPALSDISVDWFV 533
           CFSFG+G  T   L++G++  S G + F+    R+Q   ++ L+++L+P + D+S+ W +
Sbjct: 416 CFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPVVEDVSLSWHL 475

Query: 534 PDTVEALLTPREIPALYPGDQLLGYCSL 561
           P  + A +   E   ++ G +L+ Y  L
Sbjct: 476 PPGLSAKMLSPEQTVIFRGQRLISYAQL 503



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 15/34 (44%), Positives = 18/34 (52%)

Query: 1167 WATAVALAWLEHRCAAAFDEWELTAAKADCWLRA 1200
            WAT +A+ WL         EWEL   KA  W+RA
Sbjct: 725  WATILAVIWLHSNGKDLKCEWELLERKAVAWMRA 758


>gi|38195080 BCSC-1 isoform 1 [Homo sapiens]
          Length = 786

 Score =  142 bits (357), Expect = 3e-33
 Identities = 133/568 (23%), Positives = 228/568 (40%), Gaps = 96/568 (16%)

Query: 12  PLPLTDSWVRACANGPCLSVRARLTYRNPQPQPVDGVFVYPLAEAEVVSGFEAEAAGRRV 71
           P+PL    V          V A L Y N +  P++  FV+P+ E   V  FEA   G+++
Sbjct: 14  PVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKI 73

Query: 72  SFQLQSRRRSQAACCRALGPGLGTPTPRRCAQGHLVLDLAQARSTLVLPTGIIAAAGTMT 131
             +LQ + +++    +A+  G          Q  L+   + +R       G +       
Sbjct: 74  VAELQDKMKARTNYEKAISQG---------HQAFLLEGDSSSRDVFSCNVGNLQPGSKAA 124

Query: 132 VTLHSSRELPSRPDGVLHVALPTVLTPLAPPGPPGPPRPPGLCDDSPTSCFGVGSLQEEG 191
           VTL   +ELP   DG L   LP VL P                  S  SC  V +     
Sbjct: 125 VTLKYVQELPLEADGALRFVLPAVLNPRYQ-----------FSGSSKDSCLNVKT----- 168

Query: 192 LAWEELAAPRDVFSGPARCPAPYTFSFEMLVTGPCLLAGLESPSHALRADAPPHASSAAT 251
                +    D+         PYT S    +     +  ++S       +      ++A 
Sbjct: 169 ----PIVPVEDL---------PYTLSMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQ 215

Query: 252 ICVTLAEGHHCDRALEILLHPSEPHQPHLMLEGGSLSSAEYEARVRARRDFQRLQRRDSD 311
             V+LA GH  DR +E+L++ +E H P ++LE G                          
Sbjct: 216 --VSLAAGHKFDRDVELLIYYNEVHTPSVVLEMG-------------------------- 247

Query: 312 GDRQVWFLQRRFHKDILLNPVLALSFCPDL-SSKPGHLGTATRELLFLLDSSSV------ 364
                  +       ++ +P   +SF P++   +P +      E +FL+D S        
Sbjct: 248 -------MPNMKPGHLMGDPSAMVSFYPNIPEDQPSN---TCGEFIFLMDRSGSMQSPMS 297

Query: 365 ----------AHKDAIVLAVKSLPPQTLINLAVFGTLVQPLFPESRPCSDDAVQLICESI 414
                     A K+ ++L +KSLP     N+  FG+  +  FPES   +   ++     +
Sbjct: 298 SQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRV 357

Query: 415 ETLQVPSGPPDVLAALDWAVGQPQHRAYPRQLFLLTAASPMAATTHRTLELMRWHRGTAR 474
           + +Q   G  ++LA L      P    +P QLF+ T        T   ++ +R +R   R
Sbjct: 358 KLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGE--VTDTFSVIKEVRINRQKHR 415

Query: 475 CFSFGLGP-TCHQLLQGLSALSRGQAYFLRPGQRLQPMLVQALRKALEPALSDISVDWFV 533
           CFSFG+G  T   L++G++  S G + F+    R+Q   ++ L+++L+P + D+S+ W +
Sbjct: 416 CFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPVVEDVSLSWHL 475

Query: 534 PDTVEALLTPREIPALYPGDQLLGYCSL 561
           P  + A +   E   ++ G +L+ Y  L
Sbjct: 476 PPGLSAKMLSPEQTVIFRGQRLISYAQL 503



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 15/34 (44%), Positives = 18/34 (52%)

Query: 1167 WATAVALAWLEHRCAAAFDEWELTAAKADCWLRA 1200
            WAT +A+ WL         EWEL   KA  W+RA
Sbjct: 725  WATILAVIWLHSNGKDLKCEWELLERKAVAWMRA 758


>gi|38195082 BCSC-1 isoform 2 [Homo sapiens]
          Length = 415

 Score = 88.6 bits (218), Expect = 3e-17
 Identities = 104/461 (22%), Positives = 170/461 (36%), Gaps = 103/461 (22%)

Query: 12  PLPLTDSWVRACANGPCLSVRARLTYRNPQPQPVDGVFVYPLAEAEVVSGFEAEAAGRRV 71
           P+PL    V          V A L Y N +  P++  FV+P+ E   V  FEA   G+++
Sbjct: 14  PVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKI 73

Query: 72  SFQLQSRRRSQAACCRALGPGLGTPTPRRCAQGHLVLDLAQARSTLVLPTGIIAAAGTMT 131
             +LQ + +++    +A+  G          Q  L+   + +R       G +       
Sbjct: 74  VAELQDKMKARTNYEKAISQG---------HQAFLLEGDSSSRDVFSCNVGNLQPGSKAA 124

Query: 132 VTLHSSRELPSRPDGVLHVALPTVLTPLAPPGPPGPPRPPGLCDDSPTSCFGVGSLQEEG 191
           VTL   +ELP   DG L   LP VL P                  S  SC  V +     
Sbjct: 125 VTLKYVQELPLEADGALRFVLPAVLNPRYQ-----------FSGSSKDSCLNVKT----- 168

Query: 192 LAWEELAAPRDVFSGPARCPAPYTFSFEMLVTGPCLLAGLE-----SPSHALRADAPPHA 246
                +    D+         PYT S    +     +  ++     SP+  L  D     
Sbjct: 169 ----PIVPVEDL---------PYTLSMVATIDSQHGIEKVQSNCPLSPTEYLGED----- 210

Query: 247 SSAATICVTLAEGHHCDRALEILLHPSEPHQPHLMLEGGSLSSAEYEARVRARRDFQRLQ 306
               +  V+LA GH  DR +E+L++ +E H P ++LE G                     
Sbjct: 211 --KTSAQVSLAAGHKFDRDVELLIYYNEVHTPSVVLEMG--------------------- 247

Query: 307 RRDSDGDRQVWFLQRRFHKDILLNPVLALSFCPDL-SSKPGHLGTATRELLFLLDSSS-- 363
                       +       ++ +P   +SF P++   +P +      E +FL+D S   
Sbjct: 248 ------------MPNMKPGHLMGDPSAMVSFYPNIPEDQPSN---TCGEFIFLMDRSGSM 292

Query: 364 --------------VAHKDAIVLAVKSLPPQTLINLAVFGTLVQPLFPESRPCSDDAVQL 409
                          A K+ ++L +KSLP     N+  FG+  +  FPES   +   ++ 
Sbjct: 293 QSPMSSQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEE 352

Query: 410 ICESIETLQVPSGPPDVLAALDWAVGQPQHRAYPRQLFLLT 450
               ++ +Q   G  ++LA L      P    +P QLF+ T
Sbjct: 353 ALGRVKLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFT 393


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 855

 Score = 67.4 bits (163), Expect = 8e-11
 Identities = 142/596 (23%), Positives = 197/596 (33%), Gaps = 52/596 (8%)

Query: 588  PSPEEAPSAASPGTEPTGTSEPLGTGTVSAELSSPWAARDSEQSTDALTDPVTDPGPNPS 647
            PSP  A  + + GTE  G   P  +         P  +  S  S  + T+P       PS
Sbjct: 172  PSPAMARRSRAAGTE-VGLPRPAPSARPRPPTEGPRKSVSSA-SEHSTTEPSPAARRRPS 229

Query: 648  DTAIWRRIFQSSYIREQYVLTHCSASPEPGPGSTGSSESPGSQGPGSPEGSAPLEPPSQQ 707
                 +R    S        T  S+    GP + G+  +P       P+G   L PP   
Sbjct: 230  AGGGLQRPASRSLSSSA---TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT 286

Query: 708  GCRSLAWGEPAGSRSCPLPAPTPAPFKVGALSTEVLGRQHRAALAGRSLSSPPGRANQVP 767
              R  A        S PL  P+P+          +    H ++L  + L++P   A   P
Sbjct: 287  PPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQ-LATPLPLAPPSP 345

Query: 768  GRPRKPSLGAILDGPSPEPGQ---QLGQGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPS 824
              P  PSL  +   P+  P Q    LG     + +   P+P    +   PP      PP+
Sbjct: 346  SAP--PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP----QAPPA 399

Query: 825  GELAPPAVPPQAPRCHVVIRGLCGEQPMCWEVGVGLETLWGPGDGSQPPSPPVREAAWDQ 884
              L PP   P +P     +  L    P      + +  L  P   S PPSPPV +A +  
Sbjct: 400  LAL-PPLQAPPSPPASPPLSPLATPSPQA-PNALAVHLLQAP--FSPPPSPPV-QAPFSP 454

Query: 885  ALHRLTAASVVRDNEQLALRGGAETTADRGHARRCWLRALQTSKVSSAPSCFTCPVAVDA 944
                  + S    ++                     +    T    + P     P+ +  
Sbjct: 455  PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK 514

Query: 945  TTREVLPG----ALQVCSSEPAEPPGTPPASHSHLDAAPLPTVVYSKGLQRGSPAGAWDS 1000
               +  P      LQ   S PA  PG  P S S    A LP    +    +  P  A   
Sbjct: 515  PPPQAPPALATPPLQALPSPPASFPGQAPFSPS----ASLPMSPLATPPPQAPPVLAAPL 570

Query: 1001 DQNGNSKRALGDPATPT-EGPRRPP-PRPPCRLSMGRRHKLCSPDP------GQANNSEG 1052
             Q   S      PA+PT + PRRPP P P   +S  R     +P P        ++   G
Sbjct: 571  LQVPPS-----PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG 625

Query: 1053 SD---HDYLPLVRLQEAPGSFRLDAPFCAAVRISQERLCRASPFAVHRASLSPTS----- 1104
             D   H        +E  G         AA       L    P A  R    P +     
Sbjct: 626  PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAP 685

Query: 1105 -ASLPW-ALLGPGVGQGDSATASCSPSPSSGSEGPGQVDSGRGSDTEASEGAEGLG 1158
             A LPW    GPG   G   T   +  P S +  PG +D G    T   + A G G
Sbjct: 686  GAPLPWPPATGPGSADG-LCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAG 740



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 143/524 (27%), Positives = 178/524 (33%), Gaps = 108/524 (20%)

Query: 506 QRLQPMLVQALRKALEPALSDISVDWFVPDTVEALL---TPREIPALYPGDQLLGYCSLF 562
           Q L+P  V   RK   PAL  +S       +  A L    P  +PA      L   C L 
Sbjct: 278 QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLT--CQL- 334

Query: 563 RVDGFRSRPPGGQEPGWQSSGGSVFPSPEEAPSAASPGTEPTGTSEPLGTGTVSAE---L 619
                   PP    P          PS +  PS   P T P+  +  LG+ T+ A    L
Sbjct: 335 -ATPLPLAPPSPSAP----------PSLQTLPS--PPATPPSQATTSLGSPTLQATHSFL 381

Query: 620 SSP---WAARDSEQSTDALTDPVTDPGPNPSDTAIWRRIFQSSYIREQYVLTHCSASPEP 676
            SP     A    Q+  AL  P     P+P  +     +   S      +  H   +P  
Sbjct: 382 PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 441

Query: 677 GPGSTGSSESPGSQGPGSPEGSAPLEP---PSQQGCRSLA----WGEPAGSRSCPL-PAP 728
            P       SP  Q P SP  S P+ P   P  Q   SLA       P+   S P+ P+ 
Sbjct: 442 PP------PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 495

Query: 729 TPAPFKVGALSTEVLGRQHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPSPEPGQ 788
           TP P     L+   L            L+ PP    Q P     P L A+   PSP P  
Sbjct: 496 TPPPQAPPPLAAPPL-----------QLAKPP---PQAPPALATPPLQAL---PSP-PAS 537

Query: 789 QLGQGLDDSGNLLSPAPMDWDMLMEPPFL---FTAVPPSGELAPPAVPP-QAPRCHVVIR 844
             GQ        L  +P+       PP L      VPPS    PPA P  QAPR      
Sbjct: 538 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS----PPASPTLQAPRRPPT-- 591

Query: 845 GLCGEQPMCWEVGVGLETLWGPGDGSQPPSPPVRE-----AAWDQALHRLTAASVVRDNE 899
                 P     G  L     PG    PP PP R      +  D A H  +A S   +  
Sbjct: 592 ----PGPDTSVSGPRLTLALAPG----PPPPPSRSPSSTLSGPDLAGHSSSATSTPEE-- 641

Query: 900 QLALRG---GAETTADRGHARRCWLRALQTSKVSSAPSCFTCPVAVDATTREVLPGALQV 956
              LRG   G E  A         L A   +  S  P+    P+A        LP     
Sbjct: 642 ---LRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA---PPLAFRGAPGAPLPW---- 691

Query: 957 CSSEPAEPPGTPPASHSHLDAAPLPTVVYSKGLQRGSPA-GAWD 999
                  PP T P S     A  L T+  ++G +  +PA GA D
Sbjct: 692 -------PPATGPGS-----ADGLCTIYETEGPESATPAPGALD 723



 Score = 39.3 bits (90), Expect = 0.024
 Identities = 151/630 (23%), Positives = 200/630 (31%), Gaps = 112/630 (17%)

Query: 569  SRPPGGQEPGWQSSGGSVFPSPEEAPSAASPGTEPTGTSEPLGTG--TVSAELS-----S 621
            SRPP            +  P P  +P  AS  T P     PLG     +SAE +     +
Sbjct: 92   SRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG----PLGQKGLRISAEETVARGKA 147

Query: 622  PWAARDSEQSTDALTDPVTDPGPNPSDTAIWRRIFQSSYIREQYVLTHCSASPEPGPGST 681
              A + S  S  A  D  + P P     A+ RR   S     +  L   + S  P P + 
Sbjct: 148  TEAPKRSALSAGARRD-TSGPTPGTPSPAMARR---SRAAGTEVGLPRPAPSARPRPPTE 203

Query: 682  GSSESPGSQGPGSPEGSAPL--EPPSQQGCRSLAWGEPAGSRSCPLPAPTPAPFKVGALS 739
            G  +S  S    S    +P     PS  G           S + PL +P           
Sbjct: 204  GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP----------- 252

Query: 740  TEVLGRQHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPSPEPGQQLGQGLD--DS 797
                      A +G S    P RA   P +P+   L A+       P +     L    S
Sbjct: 253  ----------ARSGPSARGTP-RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301

Query: 798  GNLLSPAPMDWDMLMEPPFLFTAVPPSGEL----------APPAVPPQAPRCHVVIRGLC 847
              L +P+P        PP L  A P S  L          APP+  P AP          
Sbjct: 302  SPLATPSPSAALQSQAPPTL-PATPHSSSLTCQLATPLPLAPPS--PSAPP--------- 349

Query: 848  GEQPMCWEVGVGLETLWGPGDGSQPPSPPVREAAWDQALHRLTAASVVRDNEQLALRGGA 907
                        L+TL        PP+ P  +A        L A      +  L+     
Sbjct: 350  -----------SLQTL------PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP 392

Query: 908  ETTADRGHARRCWLRALQTSKVSSA-----PSCFTCPVAVDATTREVLPGALQVCSSEPA 962
               A    A    L  LQ      A     P     P A +A    +L        S P 
Sbjct: 393  PPQAPPALA----LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV 448

Query: 963  E----PPGTPPASHSHLDAAPLPTVVYSKGLQ--RGSPAGAWDSDQNGNSKRALGDPATP 1016
            +    PP +PP S S    +  P  + +  LQ     PA    S       +A    A P
Sbjct: 449  QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 508

Query: 1017 TEGPRRPPPRPPCRLSMGRRHKLCSPD---PGQANNSEGSDHDYLPLVRLQEAPGSFRLD 1073
                 +PPP+ P  L+      L SP    PGQA  S  +    LP+  L   P      
Sbjct: 509  PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS---LPMSPLATPPPQ---A 562

Query: 1074 APFCAAVRISQERLCRASPFAVHRASLSPTSASLPWALLGP--GVGQGDSATASCSPSPS 1131
             P  AA  +       ASP    +A   P +     ++ GP   +          S SPS
Sbjct: 563  PPVLAAPLLQVPPSPPASP--TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS 620

Query: 1132 SGSEGPGQVDSGRGSDTEASEGAEGLGGTD 1161
            S   GP       G  + A+   E L G D
Sbjct: 621  STLSGPDLA----GHSSSATSTPEELRGYD 646



 Score = 34.7 bits (78), Expect = 0.58
 Identities = 95/371 (25%), Positives = 122/371 (32%), Gaps = 56/371 (15%)

Query: 815  PFLFTAVPPSGELAPPAVPPQAPRCHVVIRGLCGEQPMCWEV-GVGLETL------WGP- 866
            P L T  PP     PP V P A R  +   G  G +P+     G+G  T+       GP 
Sbjct: 22   PGLLTPRPPGSPRPPPPVTPAALRV-LGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT 80

Query: 867  --------GDGSQPP-------SPPVREAAWDQALHRLTAASVVRDNE--QLALRGGAET 909
                       S+PP       +PP +  +         A+   R     Q  LR  AE 
Sbjct: 81   RSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEE 140

Query: 910  TADRGHARRCWLRALQTSKVSSAPSCFTCPVAVDATTREVLPGALQVCSSEPAEP----P 965
            T  RG A     R+  ++      S  T      A  R       +V    PA      P
Sbjct: 141  TVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRP 200

Query: 966  GTPPASHSHLDAAPLPTVVYSKGLQRGSPAGAWDSDQNGNSKRALGDPATPTEGPRRP-- 1023
             T     S   A+   T   S   +R   AG         + R+L   ATP   P R   
Sbjct: 201  PTEGPRKSVSSASEHSTTEPSPAARRRPSAG---GGLQRPASRSLSSSATPLSSPARSGP 257

Query: 1024 ----PPRPPCRLSMGRRHKLCSPDPGQANNSEGSDHDYLP-LVRLQEAPGSFRLDAPFCA 1078
                 PR P   S  +   L +  P Q         D  P L  L  +P    L  P  +
Sbjct: 258  SARGTPRAPAHPSQPKPKGLQALRPPQVTPPR---KDAAPALGPLSSSP----LATPSPS 310

Query: 1079 AVRISQERLCRASPFAVHRASLSPTSAS-LPWALLGPGVGQGDSATASCSPSPSSGSEGP 1137
            A   SQ       P   H +SL+   A+ LP A   P      SA  S    PS  +  P
Sbjct: 311  AALQSQAP--PTLPATPHSSSLTCQLATPLPLAPPSP------SAPPSLQTLPSPPATPP 362

Query: 1138 GQVDSGRGSDT 1148
             Q  +  GS T
Sbjct: 363  SQATTSLGSPT 373


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
          Length = 816

 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 158/655 (24%), Positives = 216/655 (32%), Gaps = 101/655 (15%)

Query: 569  SRPPGGQEPGWQSSGGSVFPSPEEAPSAASPGTEPTGTSEPLGTG--TVSAELS------ 620
            SRPP            +  P P  +P  AS  T P     PLG     +SAE +      
Sbjct: 83   SRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP----GPLGQKGLRISAEETVARGKA 138

Query: 621  ---------SPWAARDSEQSTDALTDPV---------TDPG-PNPSDTAIWRRIFQSSYI 661
                     S  A RD+   T     P          T+ G P P+ +A  R   +    
Sbjct: 139  TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRK 198

Query: 662  REQYVLTHCSASPEPG----PGSTGSSESPGSQGPGSPEGSAPLEPPSQQGCRSL----- 712
                   H +  P P     P + G  + P S+   S   + PL  P++ G  +      
Sbjct: 199  SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS--SATPLSSPARSGPSARGTPRA 256

Query: 713  ----AWGEPAGSRSCPLPAPTPAPFKVGALSTEVLGRQHRAALAGRSLSSPPGRANQVPG 768
                +  +P G ++   P  TP P K  A     LG    + LA  S S+PP      P 
Sbjct: 257  PAHPSQPKPKGLQALRPPQVTP-PRKDAA---PALGPLSSSPLATPSPSAPPS-----PS 307

Query: 769  RPRKPSLGAILDGPSPEPGQ---QLGQGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSG 825
             P  PSL  +   P+  P Q    LG     + +   P+P    +   PP      PP+ 
Sbjct: 308  AP--PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP----QAPPAL 361

Query: 826  ELAPPAVPPQAPRCHVVIRGLCGEQPMCWEVGVGLETLWGPGDGSQPPSPPVREAAWDQA 885
             L PP   P +P     +  L    P      + +  L  P   S PPSPPV +A +   
Sbjct: 362  AL-PPLQAPPSPPASPPLSPLATPSPQA-PNALAVHLLQAP--FSPPPSPPV-QAPFSPP 416

Query: 886  LHRLTAASVVRDNEQLALRGGAETTADRGHARRCWLRALQTSKVSSAPSCFTCPVAVDAT 945
                 + S    ++                     +    T    + P     P+ +   
Sbjct: 417  ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 476

Query: 946  TREVLPG----ALQVCSSEPAEPPGTPPASHSHLDAAPLPTVVYSKGLQRGSPAGAWDSD 1001
              +  P      LQ   S PA  PG  P S S    A LP    +    +  P  A    
Sbjct: 477  PPQAPPALATPPLQALPSPPASFPGQAPFSPS----ASLPMSPLATPPPQAPPVLAAPLL 532

Query: 1002 QNGNSKRALGDPATPT-EGPRRPP-PRPPCRLSMGRRHKLCSPDP------GQANNSEGS 1053
            Q   S      PA+PT + PRRPP P P   +S  R     +P P        ++   G 
Sbjct: 533  QVPPS-----PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 587

Query: 1054 D---HDYLPLVRLQEAPGSFRLDAPFCAAVRISQERLCRASPFAVHRASLSPTS------ 1104
            D   H        +E  G         AA       L    P A  R    P +      
Sbjct: 588  DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG 647

Query: 1105 ASLPW-ALLGPGVGQGDSATASCSPSPSSGSEGPGQVDSGRGSDTEASEGAEGLG 1158
            A LPW    GPG   G   T   +  P S +  PG +D G    T   + A G G
Sbjct: 648  APLPWPPATGPGSADG-LCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAG 701



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 96/398 (24%), Positives = 123/398 (30%), Gaps = 43/398 (10%)

Query: 506 QRLQPMLVQALRKALEPALSDISVDWFVPDTVEALLTPREIPALY--------PGDQL-- 555
           Q L+P  V   RK   PAL  +S       +  A  +P   P+L         P  Q   
Sbjct: 269 QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATT 328

Query: 556 -LGYCSLFRVDGFRSRPPGGQ--EPGWQSSGGSVFPSPEEAPSA-ASPGTEPTGTSEPLG 611
            LG  +L     F   PP      P  Q+      P  +  PS  ASP   P  T  P  
Sbjct: 329 SLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQA 388

Query: 612 TGTVSAELSSPWAARDSEQSTDALTDPVTDPGPNPSDTAIWRRIFQSSYIREQYVLTHCS 671
              ++  L     +        A   P   P  +PS T    +   S       V     
Sbjct: 389 PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP-SQAPPSLAAPPLQVPPSPP 447

Query: 672 ASPEPGPGSTGSSESPGSQGPGSPEGSAPLE--PPSQQGCRSLAWGEPAGSRSCPLPAPT 729
           ASP   P +T   ++P       P  + PL+   P  Q   +LA        S P   P 
Sbjct: 448 ASPPMSPSATPPPQAP------PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG 501

Query: 730 PAPFKVGA-LSTEVLGR---QHRAALAGRSLSSPPGRAN----QVPGRPRKPSLG----- 776
            APF   A L    L     Q    LA   L  PP        Q P RP  P        
Sbjct: 502 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 561

Query: 777 -----AILDGPSPEPGQQLGQGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPA 831
                A+  GP P P +     L  SG  L+          E    + + P  G  A P 
Sbjct: 562 PRLTLALAPGPPPPPSRSPSSTL--SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 619

Query: 832 VPPQAPRCHVVIRGLCGEQPMCWEVGVGLETLWGPGDG 869
              +   CH          P+ +    G    W P  G
Sbjct: 620 PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG 657



 Score = 38.9 bits (89), Expect = 0.031
 Identities = 78/290 (26%), Positives = 94/290 (32%), Gaps = 62/290 (21%)

Query: 568 RSRPPGG---QEPGWQSSGGSVFPSPEEA---PSAASPGTEPTGTSEPLGTGTVSAELSS 621
           R RP  G   Q P  +S   S  P    A   PSA      P   S+P   G  +  L  
Sbjct: 216 RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA--LRP 273

Query: 622 PWAARDSEQSTDALTDPVTDPGPNPSDTAIWRRIFQSSYIREQYVLTHCSASPEPGPGST 681
           P      + +  AL    + P   PS +A        S      + T  S    P   +T
Sbjct: 274 PQVTPPRKDAAPALGPLSSSPLATPSPSA------PPSPSAPPSLQTLPSPPATPPSQAT 327

Query: 682 GSSESPGSQGPGSPEGSAPLEP---PSQQGCRSLAW----GEPAGSRSCPL-PAPTPAPF 733
            S  SP  Q   S   S PL P   P  Q   +LA       P+   S PL P  TP+P 
Sbjct: 328 TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ 387

Query: 734 KVGALSTEVLGRQHRAALAGRSLSSPPGRANQVP-GRPRKPSLGAILDGPSPEPGQQLGQ 792
              AL+  +L             S PP    Q P   P  P +      PS  P      
Sbjct: 388 APNALAVHLLQAP---------FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS---- 434

Query: 793 GLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPP-----AVPPQAP 837
                             L  PP     VPPS   +PP       PPQAP
Sbjct: 435 ------------------LAAPPL---QVPPSPPASPPMSPSATPPPQAP 463



 Score = 37.7 bits (86), Expect = 0.069
 Identities = 60/231 (25%), Positives = 78/231 (33%), Gaps = 24/231 (10%)

Query: 815  PFLFTAVPPSGELAPPAVPPQAPRCHVVIRGLCGEQPMCWEV-GVGLETL------WGPG 867
            P L T  PP     PP V P A R  +   G  G +P+     G+G  T+       GP 
Sbjct: 22   PGLLTPRPPGSPRPPPPVTPAALRV-LGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT 80

Query: 868  DGSQPP-------SPPVREAAWDQALHRLTAASVVRDNE--QLALRGGAETTADRGHARR 918
              S+PP       +PP +  +         A+   R     Q  LR  AE T  RG A  
Sbjct: 81   RTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 140

Query: 919  CWLRALQTSKVSSAPSCFTCPVAVDATTREVLPGALQVCSSEPAEP----PGTPPASHSH 974
               R+  ++      S  T      A  R       +V    PA      P T     S 
Sbjct: 141  APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSV 200

Query: 975  LDAAPLPTVVYSKGLQRGSPAGAWDSDQNGNSKRALGDPATPTEGPRRPPP 1025
              A+   T   S   +R   AG         + R+L   ATP   P R  P
Sbjct: 201  SSASEHSTTEPSPAARRRPSAG---GGLQRPASRSLSSSATPLSSPARSGP 248



 Score = 35.0 bits (79), Expect = 0.45
 Identities = 143/616 (23%), Positives = 198/616 (32%), Gaps = 90/616 (14%)

Query: 574  GQEPGWQSSGGSVFPS-PEEAPSAASPGTEPTGTSEPLGTGTVSAELSSPWAARDSEQST 632
            G++P  + +GG    + PE AP A      PT TS P  +G    E + P        + 
Sbjct: 54   GRKPLAERAGGIGGATIPESAPRAG-----PTRTSRPPASGR--GERAPP--------AK 98

Query: 633  DALTDPVTDPGPNPSDTAIWRRIFQSSYIREQYVLTHCSASPEPGPGSTGSSESPGSQGP 692
            +    PV+ PG     T       +   I  +  +    A+  P   +  +     + GP
Sbjct: 99   NTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGP 158

Query: 693  GSPEGSAPLEPPSQQGCRSLAWGEPAGSRSCPLPAPTPAPFKVGALSTEVLGRQHRAALA 752
                   P  P      RS A G   G    P PAP+  P       TE  G +   + A
Sbjct: 159  ------TPGTPSPAMARRSRAAGTEVG---LPRPAPSARPRP----PTE--GPRKSVSSA 203

Query: 753  GRSLSSPPGRANQVPGRPRKPSLGAILDGPSPEP--------GQQLGQGLDDSGNLLSPA 804
                ++ P      P   R+PS G  L  P+                 G    G   +PA
Sbjct: 204  SEHSTTEPS-----PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA 258

Query: 805  PMDWDMLMEPPFLFTAVPPSGELAPP---AVPPQAPRCHVVIRGLCGEQPMCWEVGVGLE 861
                    +P  L    PP  ++ PP   A P   P     +       P        L+
Sbjct: 259  HPSQP---KPKGLQALRPP--QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQ 313

Query: 862  TLWGPGDGSQPPSPPVREAAWDQALHRLTAASVVRDNEQLALRGGAETTADRGHARRCWL 921
            TL        PP+ P  +A        L A      +  L+        A    A    L
Sbjct: 314  TL------PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA----L 363

Query: 922  RALQTSKVSSA-----PSCFTCPVAVDATTREVLPGALQVCSSEPAE----PPGTPPASH 972
              LQ      A     P     P A +A    +L        S P +    PP +PP S 
Sbjct: 364  PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 423

Query: 973  SHLDAAPLPTVVYSKGLQ--RGSPAGAWDSDQNGNSKRALGDPATPTEGPRRPPPRPPCR 1030
            S    +  P  + +  LQ     PA    S       +A    A P     +PPP+ P  
Sbjct: 424  SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPA 483

Query: 1031 LSMGRRHKLCSPD---PGQANNSEGSDHDYLPLVRLQEAPGSFRLDAPFCAAVRISQERL 1087
            L+      L SP    PGQA  S  +    LP+  L   P       P  AA  +     
Sbjct: 484  LATPPLQALPSPPASFPGQAPFSPSAS---LPMSPLATPPPQ---APPVLAAPLLQVPPS 537

Query: 1088 CRASPFAVHRASLSPTSASLPWALLGP--GVGQGDSATASCSPSPSSGSEGPGQVDSGRG 1145
              ASP    +A   P +     ++ GP   +          S SPSS   GP       G
Sbjct: 538  PPASP--TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA----G 591

Query: 1146 SDTEASEGAEGLGGTD 1161
              + A+   E L G D
Sbjct: 592  HSSSATSTPEELRGYD 607


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 122/508 (24%), Positives = 162/508 (31%), Gaps = 86/508 (16%)

Query: 569  SRPPGGQEPGWQSSGGSVFPSPEEAPSAASPGTEPT------GTSEPLGTGTVSAELSSP 622
            S PP G  PG +   G +  +   AP A+SP   PT       T+   GT T  A+  SP
Sbjct: 738  SLPPAGTPPGTKKVDG-ISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSP 796

Query: 623  WAARDSEQSTDALTDPVTDPGPNPSDTAIWRRIFQSSYIREQYVLTHCSA--SPEPGPGS 680
                 S Q+      P T  G    DT I       S +   ++  +  +    +  P +
Sbjct: 797  LGVSVSPQTKR----PPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPAT 852

Query: 681  TGSSESPGSQGPGSPEGSAPLEPPSQQGCRSLAWGEPAGSRSCPLPAP-----TPAPFKV 735
            T S   P  +G  +P    PL P       +L   E        LP P     TPAP + 
Sbjct: 853  THSPTPPSPKGAPTPSAVTPLSPKGV----TLPPKETPTPSVVNLPFPKEGPATPAPKQA 908

Query: 736  GALS-TEVLGRQHRAALAGRSLS---SPPGRANQVPGRPRKPSLGAILDGPSPEPGQQLG 791
             ALS T    ++ RA  A + +    SP G        P  P  G     P   P     
Sbjct: 909  PALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAA 968

Query: 792  QGLDDSGNLLSPAPMDWDMLMEPPFLFTAVP--------PSGELAPPAVPPQAPRCHVVI 843
                  G   +P+P        PP      P        P G   PPAV P +P+     
Sbjct: 969  TPPSPKGGPATPSPKG---APTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK----- 1020

Query: 844  RGLCGEQPMCWEVGVGLETLWGPGDGSQPPSPPVREAAWDQALHRLTAASVVRDNEQLAL 903
                   P       G  T       + PPSP    AA        T  +    +     
Sbjct: 1021 -----GSPAATPFPKGAST----PPAATPPSPKGSPAATPLPKGAPTTPAATLPSP---- 1067

Query: 904  RGGAETTADRGHARRCWLRALQTSKVSSAPSCFTCPVAVDATTREVLPGALQVCSSEPAE 963
            +GG  T +         L+   T   ++ PS    P    AT      GA    ++ P  
Sbjct: 1068 KGGPATPS---------LKGAPTPPAATPPS----PKGGPATPSP--KGAPMPPAATPPS 1112

Query: 964  PPG---TPPASHSHLDAAPLPTVVYSKGLQRGSPAGAWDSDQNGNSKRALGDPATPTEGP 1020
            P G   TPP  H      P  T    KG       G       G        P +P  G 
Sbjct: 1113 PKGGLATPP--HKGAPTTPAATPPSPKG-------GLATPPPKGAPTTPAATPPSPKGGL 1163

Query: 1021 RRPPPR----PPCRLSMGRRHKLCSPDP 1044
              PPP+     P       +  L +P P
Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSP 1191



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 130/578 (22%), Positives = 199/578 (34%), Gaps = 101/578 (17%)

Query: 583  GGSVFPSPEEAPS--AASPGTEPTGTSEPLGTGTVSAELSSPWAARDSEQSTDALTDPVT 640
            GG   PSP+ AP+  AA+P +   G + P   G  +   ++P + +        L  P  
Sbjct: 1230 GGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGG------LATPPH 1283

Query: 641  DPGPNPSDTAIWRRIFQSSYIREQYVLTHCSASPEPGPGSTGSSESPGSQGPGSPEGSAP 700
               PNP+                  V+T  S    P       + +P +  P SP+GS P
Sbjct: 1284 KGAPNPA------------------VVTPPSPKGGPATSPPKGAPTPPAATPPSPKGS-P 1324

Query: 701  LEPPSQQGCRSLAWGEPAGSRSCPLPAPTPAPFKVGALSTEVLGRQHRAALAGRSLSSPP 760
              PP +      A   P+   +  LPA TP+    G  +T           + +   +PP
Sbjct: 1325 GTPPPKGAPTPPAVTPPSPKGTPTLPATTPS--SKGGPTTP----------SSKEGPTPP 1372

Query: 761  GRANQVPGRPRKPSLGAILDGPSPEPGQQLGQGLDDSGNLLSPAPMDWDMLMEPPFLFT- 819
                   G P        +  PSP+ G  +       G+  SPA +       P    T 
Sbjct: 1373 AATPSHKGGPA-------MTPPSPKRGPAIPS---PKGDPTSPAVIPLSPKKAPATPVTR 1422

Query: 820  ---AVPPSGELAPPAVPPQAPRCHVVIRGLCGEQPMCWEVGVGLETLWGPGDGSQPPSPP 876
               A P  G+L PPAV P + +         G        G        P    +PP+P 
Sbjct: 1423 EGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPK 1482

Query: 877  VREAAWDQALHRLTAASVVRDNEQLALRGGAETTADRGHARRCWLRALQTSKVSSAPSCF 936
                +        T A +        +    +       +RR  +    T      P   
Sbjct: 1483 QVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTP--- 1539

Query: 937  TCPVAVDATTREVLPGALQVCSSE--PAEP-PGTPPASHSHLDAAPLPTVVYSKGLQRGS 993
                A  A    ++P A+ V S +  PA P P   PA+ S  +A+  P V  S    +G+
Sbjct: 1540 ----ATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPS--TYKGA 1593

Query: 994  PAGAWDSDQNGNSKRALGDPA----TPTEGPRRPPPRPPCRLSMGRRHKLCSPDPGQANN 1049
            P          + K  L  PA    +P E P  P   PP            SP+ G A  
Sbjct: 1594 P----------SPKELLIPPAVTSPSPKEAPTPPAVTPP------------SPEKGPATP 1631

Query: 1050 SEGSDHDYLPLV--RLQEAPGS-FRLDAPFCAAVRISQERL-CRASPFAVHRASLSPTSA 1105
            +        P+    L+++P S   +     A V  + + L  +  P A+    ++P   
Sbjct: 1632 APKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPE 1691

Query: 1106 SLPWALL----GPGVGQGDSATASCSPSPS--SGSEGP 1137
            S P        GP   +  + +    P PS  +GS+GP
Sbjct: 1692 STPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGP 1729



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 111/488 (22%), Positives = 157/488 (32%), Gaps = 85/488 (17%)

Query: 571  PPGGQEPGWQSSGGSVFPSPEEAPS--AASPGTEPTGTSEPLGTGTVSAELSSPWAARDS 628
            PP    P     GG   PSP+ AP+  AA+P +   G + P   G  +    +P + + S
Sbjct: 965  PPAATPPS--PKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGS 1022

Query: 629  EQST----DALTDPVTDPGPNPSDTAIWRRIFQSSYIREQYVLTHCSASPEPGPG--STG 682
              +T     A T P   P P+P  +     + + +       L     SP+ GP   S  
Sbjct: 1023 PAATPFPKGASTPPAATP-PSPKGSPAATPLPKGAPTTPAATL----PSPKGGPATPSLK 1077

Query: 683  SSESPGSQGPGSPEG--------SAPLEPPSQQGCRSLAWGEPAGSRSCPLPAPTPAPFK 734
             + +P +  P SP+G         AP+ P +           P    +   PA TP   K
Sbjct: 1078 GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPK 1137

Query: 735  VGALSTEVLGRQHRAALAGRS----LSSPP--GRANQVPGRPRKPSLGAILDGPSPEPGQ 788
             G  +    G     A    S    L++PP  G        P  P  G     P   P  
Sbjct: 1138 GGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1197

Query: 789  QLGQGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPS--GELAPPAVPPQAPRCHVVIRGL 846
                     G L +P+P         P    A PPS  G LA P+ P  AP         
Sbjct: 1198 PAATPPSPKGGLATPSPKG------APTTPAATPPSPKGGLATPS-PKGAPTTPAAT--- 1247

Query: 847  CGEQPMCWEVGVGLETLWGPGDGSQPPSPPVREAAWDQALHRLTAASVVRDNEQLALRGG 906
                               P     P +PP + A    A                +L+GG
Sbjct: 1248 ------------------PPSPKGGPATPPPKGAPTPPAA------------TPPSLKGG 1277

Query: 907  AETTADRGHARRCWLR--------ALQTSKVSSAPSCFTCPVAVDATTREVLPGALQVCS 958
              T   +G      +         A    K +  P   T P    +       GA    +
Sbjct: 1278 LATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPA 1337

Query: 959  SEPAEPPGTPPASHSHLDAAPLPTVVYSKGLQRGSPAGAWDSDQNGNSKRALGDPATPTE 1018
              P  P GTP    +   +   PT   SK  +  +P  A  S + G +      P +P  
Sbjct: 1338 VTPPSPKGTPTLPATTPSSKGGPTTPSSK--EGPTPPAATPSHKGGPAM----TPPSPKR 1391

Query: 1019 GPRRPPPR 1026
            GP  P P+
Sbjct: 1392 GPAIPSPK 1399



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 103/468 (22%), Positives = 162/468 (34%), Gaps = 85/468 (18%)

Query: 572  PGGQEPGWQSSGGSVFPSPEEAPSAASPGTEPTGTSE-PLGTGTVSAELSSPWAARDSEQ 630
            P    P  +       PSP+  P+  SP  +PT  +  PL      A   +   A  +  
Sbjct: 1371 PPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGA--ATP 1428

Query: 631  STDALTDPVTDPGPNPSDTAIWRRIFQSSYIREQYVLTHCSASPEPGPGSTGSSESPGSQ 690
            S   LT P   P       A                    +++P+ GP +  S   P   
Sbjct: 1429 SKGDLTPPAVTPVSLKKAPA--------------------TSAPKGGPATPSSKGDPTLP 1468

Query: 691  GPGSPEGSAPLEPPSQQGCRSLAWGEPAGSRSCPLPAPT------PAPFKVGAL------ 738
                P   +P EPP+ +   + +  + A +   P+ APT       +P +V A       
Sbjct: 1469 AVTPP---SPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRD 1525

Query: 739  ----STEVLGRQHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPSPEPGQQLGQGL 794
                +  +L ++  A LA +    PP  A  VP   + P++    + P+    ++     
Sbjct: 1526 PIAPTATLLSKKTPATLAPKEALIPP--AMTVPSPKKTPAIPTPKEAPATPSSKEASSPP 1583

Query: 795  DDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVPPQAPRCHVVIRGLCGEQPMCW 854
              + +    AP   ++L+ P    T+  P     PPAV P +P                 
Sbjct: 1584 AVTPSTYKGAPSPKELLIPP--AVTSPSPKEAPTPPAVTPPSP----------------- 1624

Query: 855  EVGVGLETLWGPGDGSQPPSPPVREAAWDQALHRLTAASVVRDNEQLALRGGAETTADRG 914
            E G        P     P SPPV  ++   +    + ASV          G     A +G
Sbjct: 1625 EKGPAT-----PAPKGTPTSPPVTPSSLKDS--PTSPASVT------CKMGATVPQASKG 1671

Query: 915  HARRCWLRALQTSKVSSAPSCFTCPVAVDATTREVLPGALQVCSSEPAEPPGTPPASHSH 974
               +    AL+   V+ AP   + P+ + A TR+      Q   S    PP  P  S  +
Sbjct: 1672 LPAKKGPTALKEVLVAPAPE--STPI-ITAPTRK----GPQTKKSSATSPPICPDPSAKN 1724

Query: 975  LDAAPLPTVVYSKGL--QRGSPAGAWDSDQNGNSKRALGDPATPTEGP 1020
                PL TV  +  L  Q+ S   A   D + + K  L  P +    P
Sbjct: 1725 GSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTP 1772



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 63/278 (22%), Positives = 106/278 (38%), Gaps = 33/278 (11%)

Query: 588  PSPEEAPS--AASPGTEPTGTSEPLGTGTVSAELSSPWAARDSEQSTDALTDPVTDPGPN 645
            PSP+EAP+  A +P +   G + P   GT ++   +P + +DS  S  ++T  +    P 
Sbjct: 1608 PSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQ 1667

Query: 646  PSD--------TAIWRRIFQSSYIREQYVLTHCSASPEPGPGSTGS-------SESPGSQ 690
             S         TA+   +   +      +       P+    S  S       S   GS+
Sbjct: 1668 ASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSK 1727

Query: 691  GPGSPEGSAPLEPPSQQGCRSLAWGEPAGSRSCPL-PAPTPAPFKVGALSTEVLGRQHRA 749
            GP S    APL P  +   ++    + + S   PL P  + A   + A + E +  +  +
Sbjct: 1728 GPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPES 1787

Query: 750  ALAGRSLSSP---PGRANQVPGRPRK-----PSLGAILDGPSP--EPGQQLGQGLDDSGN 799
            A    + S P   P   + VP  P K      S G +L+ PS    P  +     D+   
Sbjct: 1788 ASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADE-----DELLP 1842

Query: 800  LLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVPPQAP 837
            L+ P P+   +  +   +    P S  +  P    + P
Sbjct: 1843 LIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQP 1880



 Score = 34.3 bits (77), Expect = 0.76
 Identities = 25/78 (32%), Positives = 29/78 (37%), Gaps = 3/78 (3%)

Query: 159  LAPPGPPGPPRPPGLCDDSPTSCFGVGSLQEEGLAWEELAAPRDVFSGPARCPAPYTFSF 218
            LA P P G P  P     SP    G+ +   +G      A P     GPA  P P     
Sbjct: 1209 LATPSPKGAPTTPAATPPSPKG--GLATPSPKGAPTTPAATPPSPKGGPA-TPPPKGAPT 1265

Query: 219  EMLVTGPCLLAGLESPSH 236
                T P L  GL +P H
Sbjct: 1266 PPAATPPSLKGGLATPPH 1283



 Score = 30.8 bits (68), Expect = 8.4
 Identities = 35/122 (28%), Positives = 43/122 (35%), Gaps = 13/122 (10%)

Query: 119  LPTGIIAAAGTMTVTLHSSRELPSRPDGVLHVALPTVLTPLAP------PGPPGPPRPPG 172
            LP G   A  T   TL S +  P+ P  +     P   TP +P      P P G P PP 
Sbjct: 1052 LPKG---APTTPAATLPSPKGGPATPS-LKGAPTPPAATPPSPKGGPATPSPKGAPMPPA 1107

Query: 173  LCDDSPTSCFGVGSLQEEGLAWEELAAPRDVFSGPARCPAPYTFSFEMLVTGPCLLAGLE 232
                SP    G+ +   +G      A P     G A  P P         T P    GL 
Sbjct: 1108 ATPPSPKG--GLATPPHKGAPTTPAATPPSPKGGLA-TPPPKGAPTTPAATPPSPKGGLA 1164

Query: 233  SP 234
            +P
Sbjct: 1165 TP 1166


>gi|205277425 immunoglobulin superfamily, member 9 isoform a [Homo
            sapiens]
          Length = 1179

 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 95/359 (26%), Positives = 134/359 (37%), Gaps = 102/359 (28%)

Query: 681  TGSSESPGSQGPGSPEGSAPLE---PPSQQGCRSLAWGEPAGSRSCPLPAPTPAPFKVGA 737
            TG S +P + G GSP+  A L+    P     +SL WG+PAG+   P P P P P   G 
Sbjct: 784  TGKSAAPSALGSGSPDSVAKLKLQGSPVPSLRQSLLWGDPAGT---PSPHPDP-PSSRGP 839

Query: 738  LSTEVLGR-QHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPSPEPGQQLGQGLDD 796
            L  E + R      + G ++++P  R+ +    PR P+             Q+L +  D 
Sbjct: 840  LPLEPICRGPDGRFVMGPTVAAPQERSGREQAEPRTPA-------------QRLARSFDC 886

Query: 797  SGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVPPQAPRCHVVIRGLCGEQPMCWEV 856
            S +  S AP         P     + P   +APP   P +P        L G  P+   +
Sbjct: 887  SSSSPSGAPQ--------PLCIEDISP---VAPPPAAPPSP--------LPGPGPLLQYL 927

Query: 857  G------VGLETLWGPGDGSQPPSPPVREAAWDQALHRLTAASVVRDNEQLALRGGAETT 910
                   + ++  W P +   P +PP                                  
Sbjct: 928  SLPFFREMNVDGDWPPLEEPSPAAPP---------------------------------- 953

Query: 911  ADRGHARRCWLRALQTSKVSSAPSCFTCPVAVDATTREVLPGALQVCSSEPAEPPGTPPA 970
             D    RRC      TS    +P   T PV    + RE LPGA+ V +   AEPP T  A
Sbjct: 954  -DYMDTRRC-----PTSSFLRSPE--TPPV----SPRESLPGAV-VGAGATAEPPYTALA 1000

Query: 971  SHSHLDAAPLPTVVYSKGLQRGSPAGAWDSDQNG-NSKRALGDPAT-PTEGPRRPPPRP 1027
              + L    LP      GL   +P G+  S  +G  S   L  P+T P+ G     P P
Sbjct: 1001 DWT-LRERLLP------GLLPAAPRGSLTSQSSGRGSASFLRPPSTAPSAGGSYLSPAP 1052


>gi|205277423 immunoglobulin superfamily, member 9 isoform b [Homo
            sapiens]
          Length = 1163

 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 95/359 (26%), Positives = 134/359 (37%), Gaps = 102/359 (28%)

Query: 681  TGSSESPGSQGPGSPEGSAPLE---PPSQQGCRSLAWGEPAGSRSCPLPAPTPAPFKVGA 737
            TG S +P + G GSP+  A L+    P     +SL WG+PAG+   P P P P P   G 
Sbjct: 768  TGKSAAPSALGSGSPDSVAKLKLQGSPVPSLRQSLLWGDPAGT---PSPHPDP-PSSRGP 823

Query: 738  LSTEVLGR-QHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPSPEPGQQLGQGLDD 796
            L  E + R      + G ++++P  R+ +    PR P+             Q+L +  D 
Sbjct: 824  LPLEPICRGPDGRFVMGPTVAAPQERSGREQAEPRTPA-------------QRLARSFDC 870

Query: 797  SGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVPPQAPRCHVVIRGLCGEQPMCWEV 856
            S +  S AP         P     + P   +APP   P +P        L G  P+   +
Sbjct: 871  SSSSPSGAPQ--------PLCIEDISP---VAPPPAAPPSP--------LPGPGPLLQYL 911

Query: 857  G------VGLETLWGPGDGSQPPSPPVREAAWDQALHRLTAASVVRDNEQLALRGGAETT 910
                   + ++  W P +   P +PP                                  
Sbjct: 912  SLPFFREMNVDGDWPPLEEPSPAAPP---------------------------------- 937

Query: 911  ADRGHARRCWLRALQTSKVSSAPSCFTCPVAVDATTREVLPGALQVCSSEPAEPPGTPPA 970
             D    RRC      TS    +P   T PV    + RE LPGA+ V +   AEPP T  A
Sbjct: 938  -DYMDTRRC-----PTSSFLRSPE--TPPV----SPRESLPGAV-VGAGATAEPPYTALA 984

Query: 971  SHSHLDAAPLPTVVYSKGLQRGSPAGAWDSDQNG-NSKRALGDPAT-PTEGPRRPPPRP 1027
              + L    LP      GL   +P G+  S  +G  S   L  P+T P+ G     P P
Sbjct: 985  DWT-LRERLLP------GLLPAAPRGSLTSQSSGRGSASFLRPPSTAPSAGGSYLSPAP 1036


>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
          Length = 2157

 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 124/522 (23%), Positives = 164/522 (31%), Gaps = 98/522 (18%)

Query: 676  PGPG----STGSSESPGSQGPGSPEGSAPLEPPSQQGCRSLAWGEPAGSRSCPLPAPTPA 731
            PGPG    S+GSS   G  GPG   G    +  S    ++ +          PLP P P+
Sbjct: 1399 PGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPGLPLPPPPPS 1458

Query: 732  PFKVGALSTEVLGRQHRAALAGRSLSSPPGRANQVPGRPR-KPSLGAILDGPSPEP---- 786
               V  L   +         A   LSS  G      G PR KP L     GPSP P    
Sbjct: 1459 SSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQAPQGPSPRPPTRY 1518

Query: 787  -GQQLGQGLDDSGNLLSPAPM-------DWDMLMEPPFLFTAVPPSGELAPPAVPPQAPR 838
              Q++  GL    +   P PM         D     PF     PP     PP  P     
Sbjct: 1519 EPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPF-----PPKRRERPPRKPE---- 1569

Query: 839  CHVVIRGLCGEQPMCWEVGVGLETLWGPGDGSQPPSPPVREAAWDQALHRLTAASVVRDN 898
                   L  E+ +      G         GS+P  P        QA  R T    +  +
Sbjct: 1570 -------LLQEESLPPPHSSGFL-------GSKPEGP------GPQAESRDTGTEALTPH 1609

Query: 899  EQLALRGGAETTADRGHARRCWLRALQTSKVSSAPSCFTCPVAVDATTREVLPGALQVCS 958
                L       + R  +   W+  L   +  +          VD      L G  QV S
Sbjct: 1610 IWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVD------LSGDSQV-S 1662

Query: 959  SEPAEPPGTPPASHSHLDAAPLPTVVYSKGLQRGSPAGAWDSDQNGNSKRALGDPATPTE 1018
            S P     +P                  KG   G P     S    N+    G P   +E
Sbjct: 1663 SGPCSQRSSPDGG--------------LKGAAEGPPKRPGGSSPL-NAVPCEGPPG--SE 1705

Query: 1019 GPRRPPPRP--PCRLSMGRRHKLCSPDPGQANNSEGSDHDYLP-LVRLQEAPGSFRLDAP 1075
             PRRPPP P    R  + R   L  P P     S+ +D    P  +R    PG       
Sbjct: 1706 PPRRPPPAPHDGDRKELPREQPL-PPGPIGTERSQRTDRGTEPGPIRPSHRPGP---PVQ 1761

Query: 1076 FCAAVRISQERLCRASPFAVHRASLSPTSASLP----WALLGPGVGQGDSATAS-----C 1126
            F  + + S  RL         +   +  + ++P    W LL       +  + +     C
Sbjct: 1762 FGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQSKNLDSGHC 1821

Query: 1127 SPSPSS-----------GSEGPGQVD-SGRGSDTEASEGAEG 1156
             P PSS           GS GP     SG   D++    + G
Sbjct: 1822 VPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGG 1863



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 60/239 (25%), Positives = 88/239 (36%), Gaps = 55/239 (23%)

Query: 819  TAVPPSGELAPPAVPPQAPRCHVVIRGLCGEQPMCWEVGVGLETLWGP--------GDGS 870
            T+ PP  E  PPA  P  P  H   RG  G               WGP        G   
Sbjct: 395  TSRPPETEPGPPAPKPPLPPPH---RGPAGN--------------WGPPGDYPDRGGPPC 437

Query: 871  QPPSPPVREAAWDQALHRLTAASVVRDNEQLALRGGAETTADRGHARRC----WLRALQ- 925
            +PP+P   + AW Q   R  ++S +    + A R   E        RR      L+ L  
Sbjct: 438  KPPAPEDEDEAWRQ--RRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDE 495

Query: 926  ---------TSKVSSAPSCFTCPVAVDATTREV------LPGALQVCSSEPAEPPGTPPA 970
                      ++ ++ P+  + P    A  +E+       P +     +EP EP   PPA
Sbjct: 496  KFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPA 555

Query: 971  SHSHLDAAPLPTVVYSKGLQRGSPAGAWDSDQNGNSKRALGDPATPT-EGPRRPPPRPP 1028
                  + P P V  +  L  G   G+  S  +G+ + +  +P  P+ EGP  P   PP
Sbjct: 556  -----QSTPTPGVAAAPTLVSG--GGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPP 607



 Score = 37.4 bits (85), Expect = 0.090
 Identities = 59/249 (23%), Positives = 85/249 (34%), Gaps = 38/249 (15%)

Query: 568 RSRPPGGQEPGWQSSGGSVFPSPEEAPSAASPGTEPTGTSEPL-----GTGTVSAELSSP 622
           + RPP    P      G V   P E   +    +EP     P      GT  V  +L+  
Sbjct: 736 QGRPPLDFYPPGVHPSGLV---PRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLA-- 790

Query: 623 WAARDSEQSTDALTDPVTDPGPNPSDTAIWRRIFQSSYIREQYVLTHCSASPEPGPGSTG 682
           W   D   +T A   P+T P            + Q++   ++ + +     P P P    
Sbjct: 791 WVG-DVFTATPAEPRPLTSP------------LRQAADEDDKGMRSETPPVPPPPPYLAS 837

Query: 683 SSESPGSQGPGSPEGSAPLEPPSQQGCRSLAWGEPAGSRSCPLPAPTPAPFKVGALSTEV 742
               P +  PG P    PLE P   G R L W  P       +  P P        + ++
Sbjct: 838 YPGFPENGAPGPPISRFPLEEP---GPRPLPW-PPGSDEVAKIQTPPPKKEPPKEETAQL 893

Query: 743 LGRQHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPSPE------PGQQLGQGLDD 796
            G +     AGR  +   G   Q P  PR+ S      GP P       P ++ G     
Sbjct: 894 TGPE-----AGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRR 948

Query: 797 SGNLLSPAP 805
           +G +  P P
Sbjct: 949 AGPIKKPPP 957



 Score = 35.0 bits (79), Expect = 0.45
 Identities = 55/235 (23%), Positives = 77/235 (32%), Gaps = 59/235 (25%)

Query: 670  CSASPEPGPGSTGSSESPGSQGPGSPEGSAPLEPPSQQGCRSLAWGEPAGSRSCPLPAPT 729
            CS    P  G  G++E P    P  P GS+PL     +G        P GS     P P 
Sbjct: 1666 CSQRSSPDGGLKGAAEGP----PKRPGGSSPLNAVPCEG--------PPGSEPPRRPPPA 1713

Query: 730  P-----------APFKVGALSTEVLGRQHRAALAGRSLSSPPGRANQVPGRP------RK 772
            P            P   G + TE      R+    R     P R +  PG P       K
Sbjct: 1714 PHDGDRKELPREQPLPPGPIGTE------RSQRTDRGTEPGPIRPSHRPGPPVQFGTSDK 1767

Query: 773  PSLGAILDGPSPEPGQQLGQGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAV 832
             S   ++ G S +  ++L   + ++     P   DW                 EL P A 
Sbjct: 1768 DSDLRLVVGDSLKAEKELTASVTEA----IPVSRDW-----------------ELLPSAA 1806

Query: 833  PPQAPRCHVVIRGLCGEQPMCWEVGVGLETLWGPGDGSQPPSPPVREAAWDQALH 887
                P+   +  G C  +P      +  E  +G    + P S  +   A D  LH
Sbjct: 1807 ASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYG---SAGPSSSQISGGAMDSQLH 1858


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 69/280 (24%), Positives = 86/280 (30%), Gaps = 61/280 (21%)

Query: 569 SRPPGGQEPGWQSSGGSVFPSPEEAPSAASPGTEPTGTSEPLGTGTVSAELSSPWAARDS 628
           SR P G+  G    GG+  P     P     G  P G ++P G          P    + 
Sbjct: 173 SRSPPGKPQGPPPQGGNQ-PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNK 231

Query: 629 EQSTDALTDPVTDPGPNPSDTAIWRRIFQSSYIREQYVLTHCSASPEPGPGSTGSSESPG 688
            QS  A + P    GP P                           P+  P   G  + P 
Sbjct: 232 SQS--ARSPPGKPQGPPPQG----------------------GNQPQGPPPPPGKPQGPP 267

Query: 689 SQGPGSPEG----SAPLEPPSQQGCRSLAWGEPAGSRSCPLPAPTPAPFKVGALSTEVLG 744
            QG   P+G      P  PP Q G +S +   P G    P P     P            
Sbjct: 268 PQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQP------------ 315

Query: 745 RQHRAALAGRSLSSPP--GRANQVPGRPRKPSLGAILDGPSPEPGQQLGQGLDDSGNLLS 802
            Q      G+    PP  G   Q P  P KP       GP P+ G +        G    
Sbjct: 316 -QGPPPPPGKPQGPPPQGGNKPQGPPPPGKP------QGPPPQGGSKSRSARSPPGKPQG 368

Query: 803 PAPMDWDMLMEPPFLFTAVPPSG-----ELAPPAVPPQAP 837
           P   + +    PP      PP+G       APPA  PQ P
Sbjct: 369 PPQQEGNNPQGPP------PPAGGNPQQPQAPPAGQPQGP 402



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 85/384 (22%), Positives = 119/384 (30%), Gaps = 65/384 (16%)

Query: 674  PEPGPGSTGSSESPGSQGPGSPEGSAPL---EPPSQQGCRSLAWGEPAGSRSCPLP---- 726
            P+  P   G  + P  QG   P+G  P    + P  QG +S +   P G    P P    
Sbjct: 68   PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGN 127

Query: 727  ---APTPAPFKVGALSTEVLGRQHRAALAGRSLSSPPGRANQV------PGRPR--KPSL 775
                P P P K      +   +       G+    PP   N+       PG+P+   P  
Sbjct: 128  QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQG 187

Query: 776  GAILDGPSPEPGQQLGQGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVPPQ 835
            G    GP P PG+  G           P P   +    PP       P G+  P   PPQ
Sbjct: 188  GNQPQGPPPPPGKPQG-----------PPPQGGNKPQGPP-------PPGK--PQGPPPQ 227

Query: 836  APRCHVVIRGLCGEQPMCWEVGVGLETLWGPGDGSQPPSPPVREAAWDQALHRLTAASVV 895
                    R   G+         G     G      PP P   +    Q  ++       
Sbjct: 228  GDNKSQSARSPPGKPQ-------GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 280

Query: 896  RDNEQLALRGGAETTADRGHARRCWLRALQTSKVSSAPSCFTCPVAVDATTREVLPGALQ 955
               +    +GG+++ + R    +      Q       P     P            G   
Sbjct: 281  GKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPP----PPPGKPQGPPPQGGNKP 336

Query: 956  VCSSEPAEPPGTPPASHSHLDAAPLPTVVYSKGLQRGSPAGAWDSDQN------GNSKRA 1009
                 P +P G PP   S   +A  P      G  +G P    ++ Q       GN ++ 
Sbjct: 337  QGPPPPGKPQGPPPQGGSKSRSARSPP-----GKPQGPPQQEGNNPQGPPPPAGGNPQQP 391

Query: 1010 LGDPATPTEGPRRP-----PPRPP 1028
               PA   +GP RP     P RPP
Sbjct: 392  QAPPAGQPQGPPRPPQGGRPSRPP 415



 Score = 38.1 bits (87), Expect = 0.053
 Identities = 45/174 (25%), Positives = 56/174 (32%), Gaps = 20/174 (11%)

Query: 671 SASPEPGPGSTGSSESPGSQGPGSPEGSAPLEPPSQQGCRSLAWGEPAGSRSCPLP---- 726
           + +P+  P   G+        PG P+G     PP Q G +      P G    P P    
Sbjct: 33  AGNPQGAPPQGGNKPQGPPSPPGKPQG-----PPPQGGNQPQGPPPPPGKPQGPPPQGGN 87

Query: 727 ---APTPAPFKVGALSTEVLGRQHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPS 783
               P P     G        R  R+   G+    PP   NQ  G P  P       GP 
Sbjct: 88  KPQGPPPPGKPQGPPPQGDKSRSPRSP-PGKPQGPPPQGGNQPQGPPPPPGKP---QGPP 143

Query: 784 PEPGQQLGQGLDDSGNLLSPAPMDWD---MLMEPPFLFTAVPPSGELAPPAVPP 834
           P+ G +  QG    G    P P   +       PP      PP G   P   PP
Sbjct: 144 PQGGNK-PQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPP 196



 Score = 31.6 bits (70), Expect = 4.9
 Identities = 37/142 (26%), Positives = 52/142 (36%), Gaps = 9/142 (6%)

Query: 738 LSTEVLGRQHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPSPEPGQQLGQGLDDS 797
           L+ +V   +  + +AG    +PP   N+  G P  P       GP P+ G Q        
Sbjct: 19  LNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKP---QGPPPQGGNQPQGPPPPP 75

Query: 798 GNLLSPAPMDWDMLM--EPPFLFTAVPPSGELA-PPAVPPQAPRCHVVIRGLCGEQPMCW 854
           G    P P   +      PP      PP G+ +  P  PP  P+     +G  G QP   
Sbjct: 76  GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQ-GPPPQG--GNQPQGP 132

Query: 855 EVGVGLETLWGPGDGSQPPSPP 876
               G      P  G++P  PP
Sbjct: 133 PPPPGKPQGPPPQGGNKPQGPP 154


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 160/632 (25%), Positives = 215/632 (34%), Gaps = 95/632 (15%)

Query: 589  SPEEAPSAASPGTEPTGTSEPLGTGTVSAELSSPWAARDSEQSTDALTDPVTDPGPNPSD 648
            S +   S  SP  + T +   +      A L+SP     +   +  L  P++ P   P  
Sbjct: 411  SLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQ 470

Query: 649  TAIWRRIFQSSYIREQYVLTHCSA----SPEPG-------PGSTGSSESPGS-QGPGSPE 696
            T++   +   S     + L   S+    SP+         P  T SS +P S Q P +  
Sbjct: 471  TSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASL 530

Query: 697  GSAPLE-------PPSQQGCRSLAWGE---PAGSRSCPLPAP-----TPAPFKVGALSTE 741
             + PLE       PP Q     L       P     CPL AP     TP P    +++T 
Sbjct: 531  TTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATP 590

Query: 742  VLGRQHRAALAG---RSLSSPP--GRANQVPGRPRKPSLGAILDGPSPEPGQQLGQGLDD 796
                Q   ALA    + L SPP    A   P  P   +L  +   PSP     L      
Sbjct: 591  P--PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSP---- 644

Query: 797  SGNLLSPAPMDWDML----MEPPFLFTAVPP-SGELAPPAVPPQAPRCHVVIRGLCGEQP 851
               L +P+P   + L    ++ PF     PP     +PPA PP +P             P
Sbjct: 645  ---LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA---------TPP 692

Query: 852  MCWEVGVGLETLWGPGDGSQPPSPPVREAAWD--QALHRLTAASVVRDNEQLALRGGAET 909
                  +    L  P   S P SPP+  +A    QA   L A  +       A    + +
Sbjct: 693  SQAPPSLAAPPLQVPP--SPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPS 750

Query: 910  TADRGHARRCWLRALQTSKVSSAPSCFTCPVAVDATTREVLPGAL-----QVCSSEPAEP 964
                       L A    +V  +P   + P++  A      P AL     Q   S PA  
Sbjct: 751  ATPPPRVPP--LLAAPPLQVPPSPPA-SLPMSPLAKPPPQAPPALATPPLQALPSPPASF 807

Query: 965  PGTPPASHSHLDAAPLPTVVYSKGLQRGSPAGAWDSDQNGNSKRALGDPATPT-EGPRRP 1023
            PG  P S S    A LP    +    +  P  A    Q   S      PA+PT + PRRP
Sbjct: 808  PGQAPFSPS----ASLPMSPLATPPPQAPPVLAAPLLQVPPSP-----PASPTLQAPRRP 858

Query: 1024 PPRPPCRLSMGRRHKLC-----SPDPGQANNS--EGSD---HDYLPLVRLQEAPGSFRLD 1073
            P   P     G R  L       P P ++ +S   G D   H        +E  G     
Sbjct: 859  PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGP 918

Query: 1074 APFCAAVRISQERLCRASPFAVHRASLSPTS------ASLPWA-LLGPGVGQGDSATASC 1126
                AA       L    P A  R    P +      A LPW    GPG   G   T   
Sbjct: 919  EGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG-LCTIYE 977

Query: 1127 SPSPSSGSEGPGQVDSGRGSDTEASEGAEGLG 1158
            +  P S +  PG +D G    T   + A G G
Sbjct: 978  TEGPESATPAPGALDPGPSPGTSGGKAAAGAG 1009



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 145/614 (23%), Positives = 186/614 (30%), Gaps = 84/614 (13%)

Query: 588  PSPEEAPSAAS----PGTEPTGTSEPLGTGTVSAELSSPWAARDSEQSTDALTDPVTDPG 643
            PSP   PS  +    P T P+     + T  + A  S         Q   +LT P     
Sbjct: 346  PSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP--PIQVPHSLTSPSLQAP 403

Query: 644  PNPSDTAIWRRIFQSSYIREQYVLTHCSASPEPGPGSTGSSESPGSQGPGSPEGSAPLEP 703
            P+P   +  +          Q   +  + SP     S  S   P S  P SP   APL  
Sbjct: 404  PSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSL 463

Query: 704  PSQQGCRSLAWGEPAGSRSCPLPAPTPAPFKVGALSTEVLGRQHRAALAGRSLSSPPGRA 763
            P+           P  +   P  +P  +P  +  L        H       SL  PP   
Sbjct: 464  PA---------SPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLET 514

Query: 764  NQVPGRPRKPSLGAILDGP--------SPEPGQQLGQGLDDSGNLLSPAPMDWDMLMEPP 815
                  P   +  A L  P        +P P Q     L        P P     L  PP
Sbjct: 515  QSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP-LQAPP 573

Query: 816  FLFTAVPPSGELAPPAVPPQAP--RCHVVIRGLCGEQPMCWEVGVGLETLWGPGDGSQPP 873
               T  PP    +    PPQAP       ++GL                   P     P 
Sbjct: 574  SPLTTPPPETPSSIATPPPQAPPALASPPLQGL-------------------PSPPLSPL 614

Query: 874  SPPVREAAWDQALHRLTAASVVRDNEQLALRGGAETTADRGHARRCWLRALQTSKVSSAP 933
            + P  +A    AL  L A      +  L+        A    A                 
Sbjct: 615  ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674

Query: 934  SCF----TCPVAVDATTREVLPGA-----LQVCSSEPAEPPGTPPASHSHLDAAPLPTVV 984
            + F    + PV+  AT     P +     LQV  S PA PP +P A+      AP P   
Sbjct: 675  APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP--PQAPPPLAA 732

Query: 985  YSKGLQRGSPAGAWDSDQNGNSKRALGDPATPTEGPRRPPPRPPCRLSMGRRHKLCSPDP 1044
                +    PA    S       R    P      P + PP PP  L M     L  P P
Sbjct: 733  PPLQVPPSPPASPPMSPSATPPPRV---PPLLAAPPLQVPPSPPASLPMS---PLAKPPP 786

Query: 1045 GQANNSEGSDHDYLPLVRLQEAPGSFRLDAPFCAAVRISQERLCRASPFA--VHRASL-- 1100
             QA  +  +     PL  L   P SF   APF  +  +    L    P A  V  A L  
Sbjct: 787  -QAPPALATP----PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 841

Query: 1101 ----SPTSASLPWALLGPGVG-----QGDSATASCSPS-PSSGSEGPGQVDSG---RGSD 1147
                 P S +L      P  G      G   T + +P  P   S  P    SG    G  
Sbjct: 842  VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS 901

Query: 1148 TEASEGAEGLGGTD 1161
            + A+   E L G D
Sbjct: 902  SSATSTPEELRGYD 915



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 128/464 (27%), Positives = 159/464 (34%), Gaps = 96/464 (20%)

Query: 571 PPGGQEPGWQSSGGSVFPSPEEAPSAASPGTEPTGTSEPLGTGTVSAELSSPWA--ARDS 628
           PP    P   S      PSP  +P A  P   P   + P      S   S P +  A  S
Sbjct: 590 PPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPS 649

Query: 629 EQSTDALT----DPVTDPGPNPSDTAIWRRIFQSSYIREQYVLTHCSASPEPGPGSTGSS 684
            Q+ +AL          P P+P   A +                   ASP   P +T  S
Sbjct: 650 PQAPNALAVHLLQAPFSPPPSPPVQAPFSP----------------PASPPVSPSATPPS 693

Query: 685 ESPGS------QGPGSPEGSAPLEP---PSQQGCRSLA----WGEPAGSRSCPL-PAPTP 730
           ++P S      Q P SP  S P+ P   P  Q    LA       P+   S P+ P+ TP
Sbjct: 694 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATP 753

Query: 731 APFKVGALSTEVL--GRQHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPSPEPGQ 788
            P     L+   L       A+L    L+ PP    Q P     P L A+   PSP P  
Sbjct: 754 PPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP---PQAPPALATPPLQAL---PSP-PAS 806

Query: 789 QLGQGLDDSGNLLSPAPMDWDMLMEPPFL---FTAVPPSGELAPPAVPP-QAPRCHVVIR 844
             GQ        L  +P+       PP L      VPPS    PPA P  QAPR      
Sbjct: 807 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS----PPASPTLQAPRRPPT-- 860

Query: 845 GLCGEQPMCWEVGVGLETLWGPGDGSQPPSPPVRE-----AAWDQALHRLTAASVVRDNE 899
                 P     G  L     PG    PP PP R      +  D A H  +A S   +  
Sbjct: 861 ----PGPDTSVSGPRLTLALAPG----PPPPPSRSPSSTLSGPDLAGHSSSATSTPEE-- 910

Query: 900 QLALRG---GAETTADRGHARRCWLRALQTSKVSSAPSCFTCPVAVDATTREVLPGALQV 956
              LRG   G E  A         L A   +  S  P+    P+A        LP     
Sbjct: 911 ---LRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA---PPLAFRGAPGAPLPW---- 960

Query: 957 CSSEPAEPPGTPPASHSHLDAAPLPTVVYSKGLQRGSPA-GAWD 999
                  PP T P S     A  L T+  ++G +  +PA GA D
Sbjct: 961 -------PPATGPGS-----ADGLCTIYETEGPESATPAPGALD 992



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 106/430 (24%), Positives = 140/430 (32%), Gaps = 86/430 (20%)

Query: 569 SRPPGGQEPGWQSSGGSVFPSPEEAPSAASPGTEPTGTSEPLGTG--TVSAELS------ 620
           SRPP            +  P P  +P  AS  T P     PLG     +SAE +      
Sbjct: 92  SRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP----GPLGQKGLRISAEETVARGKA 147

Query: 621 ---------SPWAARDSEQSTDALTDPV---------TDPG-PNPSDTAIWRRIFQSSYI 661
                    S  A RD+   T     P          T+ G P P+ +A  R   +    
Sbjct: 148 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRK 207

Query: 662 REQYVLTHCSASPEPG----PGSTGSSESPGSQGPGSPEGSAPLEPPSQQGCRSLAWGEP 717
                  H +  P P     P + G  + P S+   S   + PL  P++ G         
Sbjct: 208 SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS--SATPLSSPARSG------PSA 259

Query: 718 AGSRSCPLPAPTPAPFKVGAL-STEVLGRQHRAALAGRSLSSPPGRANQVPGRPRKPSLG 776
            G+   P     P P  + AL   +V   +  AA A   LSS P       G   +P   
Sbjct: 260 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPV-- 317

Query: 777 AILDGPSPEPGQQLGQGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVPP-Q 835
                P       L   L  S  L +P P+       PP L T   PS    PPA PP Q
Sbjct: 318 ----PPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTL--PS----PPATPPSQ 367

Query: 836 APRCHVVIRGLCGEQPMCWEVGVGLETLWGPGDGSQPPSPPVREAAWDQALHRLTAASVV 895
           AP             PM  +    L+T+           PP+      Q  H LT+ S+ 
Sbjct: 368 APPSMTT-------PPM--QAPPSLQTI-----------PPI------QVPHSLTSPSLQ 401

Query: 896 RDNEQLALRGGAETTADRGHARRCWLRALQTSKVSSAPSCFTCPVAVDATTREVLPGALQ 955
                LAL    + T   G        +  T       +  T P    +T  +  P  LQ
Sbjct: 402 APPSPLAL-SSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPP--LQ 458

Query: 956 VCSSEPAEPP 965
              S PA PP
Sbjct: 459 APLSLPASPP 468



 Score = 32.0 bits (71), Expect = 3.8
 Identities = 60/240 (25%), Positives = 78/240 (32%), Gaps = 33/240 (13%)

Query: 815  PFLFTAVPPSGELAPPAVPPQAPRCHVVIRGLCGEQPMCWEV-GVGLETL------WGP- 866
            P L T  PP     PP V P A R  +   G  G +P+     G+G  T+       GP 
Sbjct: 22   PGLLTPRPPGSPRPPPPVTPAALRV-LGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT 80

Query: 867  --------GDGSQPP-------SPPVREAAWDQALHRLTAASVVRDNE--QLALRGGAET 909
                       S+PP       +PP +  +         A+   R     Q  LR  AE 
Sbjct: 81   RSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEE 140

Query: 910  TADRGHARRCWLRALQTSKVSSAPSCFTCPVAVDATTREVLPGALQVCSSEPAEP----P 965
            T  RG A     R+  ++      S  T      A  R       +V    PA      P
Sbjct: 141  TVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRP 200

Query: 966  GTPPASHSHLDAAPLPTVVYSKGLQRGSPAGAWDSDQNGNSKRALGDPATPTEGPRRPPP 1025
             T     S   A+   T   S   +R   AG         + R+L   ATP   P R  P
Sbjct: 201  PTEGPRKSVSSASEHSTTEPSPAARRRPSAG---GGLQRPASRSLSSSATPLSSPARSGP 257


>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
          Length = 1295

 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 63/227 (27%), Positives = 80/227 (35%), Gaps = 41/227 (18%)

Query: 671  SASPEPGPGSTGSSESPGSQGPGSP----EGSAPLEPPSQQGCRSLAWGE---------- 716
            S +P   PG   +  SP    P +P    + + PLEP      R +A             
Sbjct: 1069 SRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPP 1128

Query: 717  PAGSRSCPLPAPTP----APFKVGALSTEVLGRQHRAALAGRSLSSPPGRANQVPGRPRK 772
            P+G+RS   PAPT     AP   G    + +GR   +  AG +    PG A     RP  
Sbjct: 1129 PSGARS---PAPTRKEFGAPKSPGTTRKDNIGRSQPSPQAGLA---GPGPAGYSTARPTI 1182

Query: 773  PSLGAILDGPSPEPGQQLGQGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAV 832
            P    ++  P        G+   +S +  S        L EP     A PP   L PPA 
Sbjct: 1183 PPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQ 1242

Query: 833  PPQAPRCHVVI-RGLCGEQPMCWEVGVGLETLWGPGDGSQPPSPPVR 878
              Q P   V       G QP        LET         PP PP R
Sbjct: 1243 RLQEPLVPVAAPMPQSGPQP-------NLET---------PPQPPPR 1273



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 31/94 (32%), Positives = 39/94 (41%), Gaps = 10/94 (10%)

Query: 944  ATTREVLPGALQVCSSE-----PAEPPGTPPASHSHLDAAPLPTVVY--SKGLQRG-SPA 995
            A   E+LP  LQ  SS      P+  P T P     +   P+P++    S+   R   P 
Sbjct: 1020 AEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPP 1079

Query: 996  GAWDSDQNGNSKRALG--DPATPTEGPRRPPPRP 1027
             A  S  +      L   DPA P E  R PPPRP
Sbjct: 1080 SAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRP 1113


>gi|20143482 melanoma antigen family E, 1 [Homo sapiens]
          Length = 957

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 97/388 (25%), Positives = 137/388 (35%), Gaps = 69/388 (17%)

Query: 481 GPTCHQLLQGLSALSRGQAYFLR-----PGQRLQPMLVQALRKALEPALSDISVDWFVPD 535
           GP+  Q+LQGL A        L      P   + P + +A   + +P +S+      +P 
Sbjct: 48  GPSDSQILQGLCASEGPSTSVLPTSAEGPSTFVPPTISEASSASGQPTISEGPGTSVLPT 107

Query: 536 TVEALLTPREIPALYPGDQLLGYCSLFRVDGFR-SRPPGGQEPGWQSSGGSVFPSPEEAP 594
             E L T    P +  G  L    +L   +G   SRPP   E        SV P+  E P
Sbjct: 108 PSEGLSTSGP-PTISKG--LCTSVTLAASEGRNTSRPPTSSE----EPSTSVPPTASEVP 160

Query: 595 SAASPGTEPTGTSEPLGTGTVSAELSSPWAARDSEQSTDALTDPVTDPGPNPSDTAIWRR 654
           S + P T   GTS  +         +S     D   ST  L  P   PG +    A    
Sbjct: 161 STSLPPTPGEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPGEGPGTSVPLAA---- 216

Query: 655 IFQSSYIREQYVLTHCSASPEPGPGST---------------GSSESPGSQGPGSP-EGS 698
                    + + T   A+P+ GP ++                  E P +  P +P EG 
Sbjct: 217 --------TEGLSTSVQATPDEGPSTSVPPTATEGLSTPVPPTRDEGPSTSVPATPGEGP 268

Query: 699 APLEPPSQQGCRSLAWGEPAGSRSCPLPAPTPAPFKVGALSTEVLGRQHRAALAGRSLSS 758
           +    P+    +S++     G  S     PT        LST V       A  G S S 
Sbjct: 269 STSVLPAASDGQSISLVPTRGKGSSTSVPPTATE----GLSTSV----QPTAGEGSSTSV 320

Query: 759 PP----GRANQVPGRPRKPSLGAILDGPSPEPGQQL----GQGLDDSGNLLSPAPMDWDM 810
           PP    G +  VP    +    ++   P   P   +    G+GL  S   + P   D   
Sbjct: 321 PPTPGGGLSTSVPPTATEELSTSVPPTPGEGPSTSVLPIPGEGLSTS---VPPTASDGS- 376

Query: 811 LMEPPFLFTAVPPS-GELAPPAVPPQAP 837
                   T+VPP+ GE A   V P AP
Sbjct: 377 -------DTSVPPTPGEGASTLVQPTAP 397



 Score = 30.8 bits (68), Expect = 8.4
 Identities = 39/129 (30%), Positives = 52/129 (40%), Gaps = 18/129 (13%)

Query: 585 SVFPSPEEAPSAASPGTEPTG--TSEPLGTGTVSAELSSPWAARDSEQSTDALTDPVTDP 642
           SV P P E  S + P T   G  TS P   G  ++ L  P A      S       + +P
Sbjct: 355 SVLPIPGEGLSTSVPPTASDGSDTSVPPTPGEGASTLVQPTAPDGPGSSV------LPNP 408

Query: 643 GPNPSDTAIWRRIFQSSYIREQYVLTHCSASPEPGPGSTGSSESPGSQGPGSPEGSAPLE 702
           G  PS       +F SS   ++   + CS    P P  T +S    S+GP   EG  P+E
Sbjct: 409 GEGPST------LFSSSASVDRNP-SKCSLVL-PSPRVTKASVDSDSEGPKGAEG--PIE 458

Query: 703 PPSQQGCRS 711
               + C S
Sbjct: 459 FEVLRDCES 467


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 82/294 (27%), Positives = 104/294 (35%), Gaps = 43/294 (14%)

Query: 569 SRPPGGQEPGWQSSGGSVFPSPEEAPSAASPGTEPTGTSEPLGT-----GTVSAELSSPW 623
           +RPP    P   +SG S   +P  AP+  +PG+ PTG+ +P+G+         +    P 
Sbjct: 501 TRPPATMVP--PTSGTS---TPRTAPAVPTPGSAPTGSKKPIGSEASKKAGPKSSPRKPV 555

Query: 624 AARDSEQSTDA-LTDPVTDPG---PNPSDTAIWRRI-----FQSSYIR---EQYVLTHCS 671
             R  + + D  L+D  T P    P PS       +     F SS  R     Y + H +
Sbjct: 556 PLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLA 615

Query: 672 ASP-------EPGP-GSTGSSESPGSQG-PGSPEGSAPLEPPSQQGCRSLAWGEPAGSRS 722
            S         PGP G  G    PG  G PG P    P  PP   G   L  G P     
Sbjct: 616 GSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLP-GPPGAKGQ 674

Query: 723 CPLPAPTPAPFKVGALSTEVLGRQHRAALAGRSLSSPPGRANQ--VPGRPRKPSLGAILD 780
              P  +P     GA      G      L+G     PPGR      PG    P       
Sbjct: 675 KGDPGLSPGKAHDGA-----KGDMGLPGLSGN--PGPPGRKGHKGYPGPAGHPGEQG-QP 726

Query: 781 GPSPEPGQQLGQGLDD-SGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVP 833
           GP   PG +   G     G +  P P      +  P LF      GE   P VP
Sbjct: 727 GPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVP 780



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 41/171 (23%), Positives = 65/171 (38%), Gaps = 22/171 (12%)

Query: 585 SVFPSPEEAPSAASPGTEPTGTSEPLGTGTVSAELSSPWAARDSEQSTDALTDPVTDPGP 644
           S  P+ + APS+ +    PT    P  +  V A +S P A +  +++      P     P
Sbjct: 384 SPHPTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRP-AEKPIQRNPGMPRPPPPSTRP 442

Query: 645 NPSDTAIWRRIFQSSYIREQYVLTHCS-------------------ASPEPGPGSTGSSE 685
            P  T+  ++   +    E  + +H S                   +SP P PGST S+ 
Sbjct: 443 LPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSPAPTPGSTRSTR 502

Query: 686 SPGSQGPGSPEGSAPLEPPSQQGCRSLAWG--EPAGSRSCPLPAPTPAPFK 734
            P +  P +   S P   P+     S   G  +P GS +     P  +P K
Sbjct: 503 PPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEASKKAGPKSSPRK 553



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 50/165 (30%), Positives = 61/165 (36%), Gaps = 28/165 (16%)

Query: 672  ASPEPGP-GSTGSSESPGSQGPGSPEG-SAPLEPPSQQGCRSLAWGEPAGSRSCPLPAPT 729
            A  +PGP G  G   S G  GP  PEG    + PP   G   +  G+P G+R  P P   
Sbjct: 884  ARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMK-GKP-GARGLPGPR-- 939

Query: 730  PAPFKVGALSTEVLGRQHRAALAGR-SLSSPPGRANQVPGRPRKPSLGAILDGPSPEPGQ 788
                  G L  E  G +      G   L   PGR    PGRP        LDG   EPG 
Sbjct: 940  ------GQLGPE--GDEGPMGPPGAPGLEGQPGRKG-FPGRPG-------LDGVKGEPGD 983

Query: 789  QLGQGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVP 833
                     G +     M +  L+  P +       G + PP VP
Sbjct: 984  P-----GRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVP 1023



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 52/206 (25%), Positives = 69/206 (33%), Gaps = 46/206 (22%)

Query: 674  PEPGPGSTGSSESPGSQGPGSPEGSAPLEPPSQQGCRSLAWGEPAGSRSCPLPAPTPAPF 733
            P   PG+ G    PG QGP  P G     PP + G +    G P       LP       
Sbjct: 1118 PSGPPGTKGLPGEPGPQGPQGPIG-----PPGEMGPK----GPPGAVGEPGLPGEAGMKG 1168

Query: 734  KVGALSTE----VLGRQHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPSPEPGQQ 789
             +G L T     ++G++    L G S    P       G P          GP  E G++
Sbjct: 1169 DLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDP----------GPDGEHGEK 1218

Query: 790  LGQGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVPPQAPRCHVVIRGLCGE 849
              +GL           M  D    PP +     P G+        Q  +     +G  G 
Sbjct: 1219 GQEGL-----------MGEDGPPGPPGVTGVRGPEGKSG-----KQGEKGRTGAKGAKGY 1262

Query: 850  QPMCWEVGVGLETLWGPGDGSQPPSP 875
            Q    E+GV       PGD   P +P
Sbjct: 1263 QGQLGEMGV-------PGDPGPPGTP 1281



 Score = 35.0 bits (79), Expect = 0.45
 Identities = 59/227 (25%), Positives = 82/227 (36%), Gaps = 23/227 (10%)

Query: 944  ATTREVLPGALQVCSSEPAEPPGTPPASHSHLDAAPLPTVVYSKGLQRGSPAGAWDSDQN 1003
            A T    P      SS PA  PG+  ++       P PT   S    R +PA        
Sbjct: 474  ARTSTHKPPPFTALSSSPAPTPGSTRSTRPPATMVP-PTSGTST--PRTAPAVPTPGSAP 530

Query: 1004 GNSKRALGDPATPTEGPRRPPPRP-PCRLSMGRRHKLCS-----PDPGQANNSEGSDHDY 1057
              SK+ +G  A+   GP+  P +P P R     R    S     P P Q   S+ +    
Sbjct: 531  TGSKKPIGSEASKKAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQT---- 586

Query: 1058 LPLVRLQEAPGSFRLDAPFCAAVRISQERLCRASPFAVHRASLSPT-SASLPW--ALLG- 1113
             P + L  AP  F   +P   +   S   L  ++PF +      P     LP    L G 
Sbjct: 587  TPALVL--APAQFLSSSPRPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGL 644

Query: 1114 PGVGQGDSATASCSPSPSSGSEGPGQVDSGRG----SDTEASEGAEG 1156
            PG+           P  + G  GP      +G    S  +A +GA+G
Sbjct: 645  PGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKG 691



 Score = 35.0 bits (79), Expect = 0.45
 Identities = 54/202 (26%), Positives = 69/202 (34%), Gaps = 50/202 (24%)

Query: 678  PGSTGSSESPGSQGPGSPEGSAPLEPPSQQGCRSLAWGEPAGSRSCPLPAPTPAPFKVGA 737
            PG  G   +PG  GP  P GS    PP  +G         A  R  P     PA      
Sbjct: 1032 PGMPGGMGTPGEPGPQGPPGSR--GPPGMRG---------AKGRRGPRGPDGPA------ 1074

Query: 738  LSTEVLGRQHRAALAGRSLSSPPGRANQVPGRPRKPSLGAI-----------LDGPSPEP 786
                  G Q       R L  PPG   + PGRP +  +              + GPS  P
Sbjct: 1075 ------GEQ-----GSRGLKGPPGPQGR-PGRPGQQGVAGERGHLGSRGFPGIPGPSGPP 1122

Query: 787  GQQLGQGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVPPQA-PRCHVVIRG 845
            G +   G         P P      + PP       P G +  P +P +A  +  +   G
Sbjct: 1123 GTKGLPG--------EPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLG 1174

Query: 846  LCGEQPMCWEVG-VGLETLWGP 866
              GEQ +  + G  GLE   GP
Sbjct: 1175 TPGEQGLIGQRGEPGLEGDSGP 1196



 Score = 31.6 bits (70), Expect = 4.9
 Identities = 44/147 (29%), Positives = 56/147 (38%), Gaps = 19/147 (12%)

Query: 674  PEPGPGSTGSSESPGSQGPGSPEGSAPLEPPSQQGCRSLAWGEPA--GSRSCP-LPAPTP 730
            P    G  G   S G +GP  P+G      P QQG      GE    GSR  P +P P+ 
Sbjct: 1067 PRGPDGPAGEQGSRGLKGPPGPQGRP--GRPGQQGVA----GERGHLGSRGFPGIPGPSG 1120

Query: 731  APFKVGALSTE-VLGRQHRAALAGR-SLSSPPGRANQVPGRPRKPSLGAILDGPSPEPGQ 788
             P   G        G Q      G      PPG   + PG P +  +   L GP   PG+
Sbjct: 1121 PPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGE-PGLPGEAGMKGDL-GPLGTPGE 1178

Query: 789  Q--LGQ----GLDDSGNLLSPAPMDWD 809
            Q  +GQ    GL+     + P  +  D
Sbjct: 1179 QGLIGQRGEPGLEGDSGPMGPDGLKGD 1205


>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
            potassium channel 4 [Homo sapiens]
          Length = 1203

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 65/215 (30%), Positives = 85/215 (39%), Gaps = 30/215 (13%)

Query: 671  SASPEPGPGS--TGSSESPGSQ---GPGSPEGSAPLEPPSQQGCRSLAWGEPAGSRSCPL 725
            SASP   P    T SS S   Q   G  +P G +PL P S       A G P+       
Sbjct: 839  SASPASSPSQVDTPSSSSFHIQQLAGFSAPAGLSPLLPSSSSSPPPGACGSPS------- 891

Query: 726  PAPTPAPFKVGALSTEVLGRQHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPSPE 785
             APTP+    G  +T + G  H     G SLSS        P +P   S  A    P+P 
Sbjct: 892  -APTPS---AGVAATTIAGFGHFHKALGGSLSSSDSPL-LTPLQPGARSPQAAQPSPAP- 945

Query: 786  PGQQLGQGLDDSGNLLSPAPMDWD------MLMEPPFLFTAVPPSGELAPPAVPPQAPRC 839
            PG + G GL +  + L P P           L +PP   +    +G L+ P  PP+ P  
Sbjct: 946  PGARGGLGLPE--HFLPPPPSSRSPSSSPGQLGQPPGELSLGLATGPLSTPETPPRQPEP 1003

Query: 840  HVVIRGLC-GEQPMCWEVGVGLETLWGPGDGSQPP 873
              ++ G   G  P+ +    GL     PG    PP
Sbjct: 1004 PSLVAGASGGASPVGFTPRGGLSP---PGHSPGPP 1035



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 73/294 (24%), Positives = 98/294 (33%), Gaps = 47/294 (15%)

Query: 490  GLSALSRGQAYFLRPGQRLQPMLVQALRKALEPALSDISVDWFVPDTVEALLTPREIPAL 549
            GL  L  GQ    R  +RLQ ++  AL  A  PA S   VD           TP    + 
Sbjct: 813  GLGNLGAGQTP--RHLKRLQSLIPSALGSA-SPASSPSQVD-----------TPSS--SS 856

Query: 550  YPGDQLLGYCSLFRVDGFRSRPPGGQEPGWQSSGGSVFPSPEEAPSAASPGTEPTGTSEP 609
            +   QL G+ +           P G  P   SS  S  P    +PSA +P      T+  
Sbjct: 857  FHIQQLAGFSA-----------PAGLSPLLPSSSSSPPPGACGSPSAPTPSAGVAATTIA 905

Query: 610  LGTGTVSAELSSPWAARDSEQSTD----ALTDPVTDPGPNPSDTAIWRRIFQSSYIREQY 665
             G G     L    ++ DS   T     A +     P P P              + E +
Sbjct: 906  -GFGHFHKALGGSLSSSDSPLLTPLQPGARSPQAAQPSPAPPGAR------GGLGLPEHF 958

Query: 666  VLTHCSA-SPEPGPGSTGSSESPGSQGPGSPEGSAPLEPPSQQGCRSLAWGEPAGSRSCP 724
            +    S+ SP   PG  G      S G  +   S P  PP Q    SL  G   G+    
Sbjct: 959  LPPPPSSRSPSSSPGQLGQPPGELSLGLATGPLSTPETPPRQPEPPSLVAGASGGASPVG 1018

Query: 725  L--------PAPTPAPFKVGALSTEVLGRQHRAALAGRSLSSPPGRANQVPGRP 770
                     P  +P P +    +       H + L   + S PP +  Q  G P
Sbjct: 1019 FTPRGGLSPPGHSPGPPRTFPSAPPRASGSHGSLLLPPASSPPPPQVPQRRGTP 1072



 Score = 30.8 bits (68), Expect = 8.4
 Identities = 54/203 (26%), Positives = 69/203 (33%), Gaps = 38/203 (18%)

Query: 571  PPGGQEPGWQSSGGSVFPSPEE-------APSAASPGTEPTGTSEP-LGTGTVSAELSSP 622
            PP   EP    +G S   SP         +P   SPG   T  S P   +G+  + L  P
Sbjct: 997  PPRQPEPPSLVAGASGGASPVGFTPRGGLSPPGHSPGPPRTFPSAPPRASGSHGSLLLPP 1056

Query: 623  WAARDSEQSTDALTDPVTDPGPNPSD----TAIWRRIFQSSYIREQYVLTHCSAS----- 673
             ++    Q       P   PG    D    +A    + Q      +    H S       
Sbjct: 1057 ASSPPPPQVPQRRGTPPLTPGRLTQDLKLISASQPALPQDGAQTLRRASPHSSGESMAAF 1116

Query: 674  ---PEPGPGSTGSSESPGSQGPGSPEGSAP--------------LEPP-SQQGCRSLAWG 715
               P  G GS GS  S G   PG P G+ P              L PP S  G R+ + G
Sbjct: 1117 PLFPRAGGGSGGSGSSGGLGPPGRPYGAIPGQHVTLPRKTSSGSLPPPLSLFGARATSSG 1176

Query: 716  EP---AGSRSCPLPAPTPAPFKV 735
             P   AG +  P   P P   K+
Sbjct: 1177 GPPLTAGPQREPGARPEPVRSKL 1199


>gi|41281612 zinc finger protein 828 [Homo sapiens]
          Length = 812

 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 76/317 (23%), Positives = 109/317 (34%), Gaps = 57/317 (17%)

Query: 543 PREIPALYPGDQLLGYCSLFRVDGFRSRPPGGQEPGWQSSGGSV-------FPSPEEAPS 595
           P+ IPAL    Q LG  S+   +  +  P    EP  Q  G  V        PSPE +  
Sbjct: 124 PKSIPALSMETQKLG--SVLSPESPKPTPLTPLEP--QKPGSVVSPELQTPLPSPEPSKP 179

Query: 596 AASPGTEPTGTSEPLGTGTVSAELSSPWAARDSEQSTDALTDPVTDPGPNPSDTAIWRRI 655
           A+    EP   S P+      A + SP   + +  S +++   +++P P           
Sbjct: 180 ASVSSPEPP-KSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQ-------- 230

Query: 656 FQSSYIREQYVLTHCSASPEP-GPGSTGSSESPGSQGPGSPEGSAPLEPPSQQGCRSLAW 714
                          S  PE  GP S  S ESP       P G +P   P  +       
Sbjct: 231 ---------------SHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTS 275

Query: 715 GEPAGSRSCPLPAPTPAPFKVGALSTEVLGRQHRAALAGRSLSSPPG---------RANQ 765
            EP      P P+ +P P+K     +    R   A   G     PPG          A+ 
Sbjct: 276 PEPRK----PSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASS 331

Query: 766 VPGRPRKPSLGAILDGP-------SPEPGQQLGQGLDDSGNLLSPAPMDWDMLMEPPFLF 818
            P +P KP+  ++  GP       SP P +        S    S +P  W      P  +
Sbjct: 332 GPWKPAKPA-PSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESW 390

Query: 819 TAVPPSGELAPPAVPPQ 835
            + PP      P + P+
Sbjct: 391 KSGPPELRKTAPTLSPE 407


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 56/186 (30%), Positives = 70/186 (37%), Gaps = 24/186 (12%)

Query: 672 ASPEPGPGSTGSSESPGSQGPGSPEGSAPLEPPSQQGCRSLAWGEPAGSR-SC-PLPA-- 727
           A+PEP P         G Q PG P    PL P       +     P GS  SC P+PA  
Sbjct: 85  AAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAA 144

Query: 728 -----PTPAPFKVGALSTEVLGRQHRAALAGRSLSSPPGRA-NQVPGRPRKPSLGAILDG 781
                P PAP    A   +  G    AA AG      PG      PG+P  P     L+G
Sbjct: 145 AVAAGPEPAP----AGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNG 200

Query: 782 P-----SPEPGQQLGQGLDDSGNLLSPAP---MDWDMLMEPPFLFTAVPPS-GELAPPAV 832
                 S          +++    L P P       ++  PPF+  A PP+    +PPA 
Sbjct: 201 SAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAA 260

Query: 833 P-PQAP 837
           P P AP
Sbjct: 261 PAPAAP 266



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 97/418 (23%), Positives = 132/418 (31%), Gaps = 110/418 (26%)

Query: 571 PPGGQ-EPGWQSSGGSVFPSPEEAPSAASPGTEPTGTSEPLGTGTVSAELSSPWAARDSE 629
           PP  +  P  + S GS  P P  A  AA P   P G ++P G   ++A            
Sbjct: 121 PPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAAR----------- 169

Query: 630 QSTDALTDPVTDPGPNPSDTAIWRRIFQSSYIREQYVLTHCSASPEPGPGSTGSSESPGS 689
                   P   PGP P                           P PGPG          
Sbjct: 170 ------AGPGPGPGPGP--------------------------GPGPGPGKPA------- 190

Query: 690 QGPGSPE---GSAPLEPPSQQGCRSLAWGEPAGSRSCPLPAPTPAPFKVGALSTEVLGRQ 746
            GPG+ +   GSA L         +++      +   PLP P  AP  V      V    
Sbjct: 191 -GPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPA-APGTVIQTPPFV---- 244

Query: 747 HRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPSPEPGQQLGQGLDDSGNLLSPAPM 806
                     ++PP  A   P  P  P+  A    P P P                PAP 
Sbjct: 245 --------GAAAPPAPA--APSPPAAPAPAAPAAAPPPPP----------------PAPA 278

Query: 807 DWDMLMEPPFLFTAVPPSGELAPPAVPPQAPRCHVVIRGLCGEQPMCWEVGVGLETLWGP 866
               L  PP    A PP+   A PAVPP A   +    G             G+    GP
Sbjct: 279 ---TLARPPG-HPAGPPT---AAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGP 331

Query: 867 GDGSQPPSPPVREAAWDQALHRLTAASVVRDNEQLALRGGAETTADRGHARRCWLRALQT 926
           G  +  P+P V+  +  + +     A+     + LA  G A T A            +  
Sbjct: 332 GAAAAAPAPGVKAESPKRVVQAAPPAA-----QTLAASGPASTAAS---------MVIGP 377

Query: 927 SKVSSAPSCFTCPVAVDATTREVLPGALQVCSSEPAEPPGTPPASHSHLDAAPLPTVV 984
           +   + PS    P     T   +  GA    +   +    TP A+ S + A   PTV+
Sbjct: 378 TMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSR---TPTATTSGIRATLTPTVL 432



 Score = 35.8 bits (81), Expect = 0.26
 Identities = 79/345 (22%), Positives = 106/345 (30%), Gaps = 70/345 (20%)

Query: 748  RAALAGRS-----LSSPPGRANQVPGRPRKPSLGAILDGPSPEPGQQLGQGLDDSGNLLS 802
            RAA AG         SP G A   P  P + + GA    P P P    G+     G    
Sbjct: 51   RAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGA---APEPPPA---GRARPGGGGPQR 104

Query: 803  PAPMDWDMLMEPPFLFTAVPPSGELAPPAVPPQAPRCHVVIRGLCGEQPMCWEVGVG--- 859
            P P      + P       PP+ +L PP   P+         G C   P    V  G   
Sbjct: 105  PGPPSPRRPLVPA---GPAPPAAKLRPP---PEGSA------GSCAPVPAAAAVAAGPEP 152

Query: 860  -------------LETLWGPGDGSQP---PSPPVREAAWDQALHRLTAASVVRDNEQLAL 903
                         L    GPG G  P   P P   + A   A   L  ++ + ++   A 
Sbjct: 153  APAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAA- 211

Query: 904  RGGAETTADRGHARRCWL-------RALQT-----SKVSSAPSCFTCPVAVDATTREVLP 951
               A +  + G A    L         +QT     +    AP+  + P A         P
Sbjct: 212  -APAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAP 270

Query: 952  GALQVCSSEPAEPPGTPPASHSHLDAAPLPTVVYSKGLQRGSPAGAWDSDQNGNSKRALG 1011
                   +  A PPG P    +   A P P    + G    +PA A           A G
Sbjct: 271  PPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPA----------PAAG 320

Query: 1012 DPA----TPTEGPRRPPPRPPCRLSMGRRHKLCSPDPGQANNSEG 1052
             PA     P  G     P P  +    +R    +P   Q   + G
Sbjct: 321  GPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASG 365



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 45/158 (28%), Positives = 55/158 (34%), Gaps = 41/158 (25%)

Query: 22  ACANGPCLSVRARLTYRNPQPQPVDGVFVYPLAEAEVVSGFEAEAAGRRVSFQLQSRRRS 81
           A A  P   V+A    R  Q  P       P A+    SG  + AA   +   +Q    S
Sbjct: 333 AAAAAPAPGVKAESPKRVVQAAP-------PAAQTLAASGPASTAASMVIGPTMQGALPS 385

Query: 82  QAACCRALGPGLGTPTPRRCAQGHLVLDLAQARSTLVLPTGIIAAAGTMTVTLHSSRELP 141
            AA      P  GTPT                     LP G   AAG +T +L  SR   
Sbjct: 386 PAA---VPPPAPGTPTG--------------------LPKG---AAGAVTQSL--SRTPT 417

Query: 142 SRPDGVLHVALPTVLTPLAPPGPPGPPR------PPGL 173
           +   G+     PTVL P  P  P  P        PPG+
Sbjct: 418 ATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGM 455



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 49/174 (28%), Positives = 55/174 (31%), Gaps = 36/174 (20%)

Query: 90  GPGLGTPTPRRCAQ---GHLVL-----------DLAQARSTLVLPTGIIAAAGTMTVTL- 134
           GPG G P     AQ   G   L            L       +LP    AA GT+  T  
Sbjct: 183 GPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPP 242

Query: 135 HSSRELPSRPDGVLHVALPTVLTPLAPPGPPGP-----PRPPGLCDDSPTSCFGVGSLQE 189
                 P  P      A P    P A P PP P      RPPG     PT+   V     
Sbjct: 243 FVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVP---- 298

Query: 190 EGLAWEELAAPRDVFSGPARCPAPYTFSFEMLVTGPCLLAGLESPSHALRADAP 243
                   AA     +G A  PAP          GP  ++G   P  A  A AP
Sbjct: 299 -----PPAAAQNGGSAGAAPAPAP-------AAGGPAGVSGQPGPGAAAAAPAP 340


>gi|27735129 hypothetical protein LOC148345 [Homo sapiens]
          Length = 656

 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 91/329 (27%), Positives = 116/329 (35%), Gaps = 78/329 (23%)

Query: 588 PSPEEAPSAASPGTEPTGTSEPLGTGTVSAELSSPWAARDSEQSTDALTDPVTDPGPNPS 647
           P P EA     P    T  SEP     V    +SPW  R    +  ALT PV+    +PS
Sbjct: 298 PPPGEAGIPGHPTPPATLPSEP-----VEGVQASPWRPRPVLPTHPALTLPVSSDASSPS 352

Query: 648 DTAIWRRIFQSSYIREQYVLTHCSASPEPGPGSTGSSESPGSQGPGSPEGSAPLEPPSQQ 707
             A            E  +++  S +   G G+    + P ++ PGSP            
Sbjct: 353 PPA------PRPERPESLLVSGPSVTLTEGLGTVRPEQDP-AKSPGSP-----------L 394

Query: 708 GCRSLAWGEPAGSRSCPLPAPTPAPFKVGALSTEV--LGRQHRAALAGRSLSS--PPGRA 763
             R L+ G+ A        AP P   + G  S E   L R  RA LA   L S   PG  
Sbjct: 395 LLRGLSSGDVA--------APEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRSPGEP 446

Query: 764 NQV-------------PGRPRKPSLGAILDGPSPEPGQQL-GQGLD---------DSGNL 800
            +              PG PR+ + G  +D  S EP Q + G GL           + ++
Sbjct: 447 QETCSGTEVERPRQTGPGLPREGARGH-MDLSSSEPSQDIEGPGLSILPARDATFSTPSV 505

Query: 801 LSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVPPQAPRCHVVIRGLCGEQPMCWEVG--- 857
             P P  W  L   P L T +P     AP AV P  P     +R      P    VG   
Sbjct: 506 RQPDPSAW--LSSGPEL-TGMPRVRLAAPLAVLPMEPLPPEPVRPAALLTPEASSVGGPD 562

Query: 858 ------------VGLETLWGPGDGSQPPS 874
                       VG E  WG    S PPS
Sbjct: 563 QARYLESAPGWPVGQEE-WGVAHTSSPPS 590



 Score = 35.4 bits (80), Expect = 0.34
 Identities = 66/237 (27%), Positives = 92/237 (38%), Gaps = 41/237 (17%)

Query: 7   PSSWTPLPLTDSWVRACANG---PCLSVRARLTYRNPQPQP-VDGVFVYPLAEAEVVSGF 62
           P  WT     +S+ +   +G   P  +   R T   P P P      V P A ++V +  
Sbjct: 187 PVLWT----VESFFQCVGSGTEPPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAA- 241

Query: 63  EAEAAGRRVSFQLQSRRRSQAACCRALGPGLGTPTPRRCAQ--GHLVLDLAQARSTLVLP 120
              AA   +S  L   R S A   + LGP L T  P R  Q    ++  + QA+     P
Sbjct: 242 -GPAAQEWLSRDLL-HRPSDALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPP 299

Query: 121 TGIIAAAG--TMTVTLHSS-----RELPSRPDGVL--HVALP-TVLTPLAPPGPPG--PP 168
            G     G  T   TL S      +  P RP  VL  H AL   V +  + P PP   P 
Sbjct: 300 PGEAGIPGHPTPPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPE 359

Query: 169 RPPGLCDDSP--TSCFGVGSLQEE--------------GLAWEELAAPRDVFSGPAR 209
           RP  L    P  T   G+G+++ E              GL+  ++AAP  +   P +
Sbjct: 360 RPESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQ 416


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 47/161 (29%), Positives = 57/161 (35%), Gaps = 13/161 (8%)

Query: 674 PEPGPGSTGSSESPGSQGPGSPEGSAPLEPPSQQGCRSLAWGEPAGSRSCPLPAPTPAPF 733
           P P PG+      P    P  P G+A   PPS     +   G P    S P P P P   
Sbjct: 246 PVPPPGALPPGIPPAMPPPPMPPGAAGHGPPS---AGTPGAGHPGHGHSHPHPFP-PGGM 301

Query: 734 KVGALSTEVLGRQHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPSPEPGQQLGQG 793
               +S   L   H     G   + PPG   Q P RP        +  P P P     +G
Sbjct: 302 PHPGMSQMQLA-HHGPHGLGHPHAGPPGSGGQPPPRPPPG-----MPHPGPPPMGMPPRG 355

Query: 794 LDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVPP 834
                 +  P PM    +  PP L   +PP G   PP  PP
Sbjct: 356 PPFGSPMGHPGPMPPHGMRGPPPL---MPPHGYTGPPRPPP 393



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 58/240 (24%), Positives = 71/240 (29%), Gaps = 55/240 (22%)

Query: 571 PPGGQEPGWQSSGGSVFPSPEEAPSAASPGTEPTGTSEPLGTGTVS---AELSSPWAARD 627
           PPG   PG        FP P   P A  PG  P     P+  G          +P A   
Sbjct: 234 PPGMPPPG-------SFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHP 286

Query: 628 SEQSTDALTDPVTDPG--PNPSDTAIWRRIFQSSYIREQYVLTHCSASPEPGPGSTGSSE 685
               +     P   PG  P+P            S ++  +   H    P  GP  +G  +
Sbjct: 287 GHGHSHPHPFP---PGGMPHPG----------MSQMQLAHHGPHGLGHPHAGPPGSG-GQ 332

Query: 686 SPGSQGPGSPEGSAPLEPPSQQGCRSLAWGEPAGSRSCPLPAPTPAPFKVGALSTEVLGR 745
            P    PG P    P  PP     R   +G P G      P P P               
Sbjct: 333 PPPRPPPGMPH---PGPPPMGMPPRGPPFGSPMGH-----PGPMPP-------------- 370

Query: 746 QHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPSPEPGQQLGQGLDDSGNLLSPAP 805
                + G     PP   +   G PR P  G    GP P P       +   G L  P P
Sbjct: 371 ---HGMRGPPPLMPP---HGYTGPPRPPPYG-YQRGPLPPPRPTPRPPVPPRGPLRGPLP 423


>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
          Length = 1612

 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 66/240 (27%), Positives = 83/240 (34%), Gaps = 51/240 (21%)

Query: 671  SASPEPGPGSTGSSESPGSQGPGSP----EGSAPLEPPSQQGCRSLAWGE---------- 716
            S +P   PG   +  SP    P +P    + + PLEP      R +A             
Sbjct: 1108 SRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPP 1167

Query: 717  PAGSRSCPLPAPTPAPFK-VGALSTEVLGRQHRAALA----------GRSLSSP------ 759
            P+G+RS   PAPT   F  +GA  +  + R+   A            GRS  SP      
Sbjct: 1168 PSGARS---PAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAG 1224

Query: 760  PGRANQVPGRPRKPSLGAILDGPSPEPGQQLGQGLDDSGNLLSPAPMDWDMLMEPPFLFT 819
            PG A     RP  P    ++  P        G+   +S +  S        L EP     
Sbjct: 1225 PGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQA 1284

Query: 820  AVPPSGELAPPAVPPQAPRCHVVI-RGLCGEQPMCWEVGVGLETLWGPGDGSQPPSPPVR 878
            A PP   L PPA   Q P   V       G QP        LET         PP PP R
Sbjct: 1285 AFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQP-------NLET---------PPQPPPR 1328



 Score = 39.3 bits (90), Expect = 0.024
 Identities = 57/231 (24%), Positives = 83/231 (35%), Gaps = 35/231 (15%)

Query: 944  ATTREVLPGALQVCSSE-----PAEPPGTPPASHSHLDAAPLPTVVY--SKGLQRG-SPA 995
            A   E+LP  LQ  SS      P+  P T P     +   P+P++    S+   R   P 
Sbjct: 1059 AEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPP 1118

Query: 996  GAWDSDQNGNSKRALG--DPATPTEGPRRPPPR---PPCRLSMGRRHKLCSPDPGQANNS 1050
             A  S  +      L   DPA P E  R PPPR   PP R +  +R     P P     S
Sbjct: 1119 SAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQR-----PPPPSGARS 1173

Query: 1051 EGSDHDYLPLVRLQEAPGSFRLDAPFCAAVRISQERLCRASPFAVHRASLSPTSASLPWA 1110
                      +    +PG  R            +E     SP    + ++  +  S    
Sbjct: 1174 PAPTRKEFGGIGAPPSPGVAR------------REMEAPKSPGTTRKDNIGRSQPSPQAG 1221

Query: 1111 LLGPGVGQGDSATASCSPSPS--SGSEGPGQVDSGR---GSDTEASEGAEG 1156
            L GPG     +A  +  P     S  +   +  +GR    S ++ SE ++G
Sbjct: 1222 LAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKG 1272



 Score = 32.3 bits (72), Expect = 2.9
 Identities = 26/83 (31%), Positives = 38/83 (45%), Gaps = 7/83 (8%)

Query: 126  AAGTMTVTLHSSRELPSR-PDGVLHVALPTVLTPLAPPGPPGPP-RPP---GLCDDSPT- 179
            +A +  +    +  LP + P   L    P    P+APP  P PP RPP   G    +PT 
Sbjct: 1119 SAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTR 1178

Query: 180  -SCFGVGSLQEEGLAWEELAAPR 201
                G+G+    G+A  E+ AP+
Sbjct: 1179 KEFGGIGAPPSPGVARREMEAPK 1201


>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
          Length = 1350

 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 66/240 (27%), Positives = 83/240 (34%), Gaps = 51/240 (21%)

Query: 671  SASPEPGPGSTGSSESPGSQGPGSP----EGSAPLEPPSQQGCRSLAWGE---------- 716
            S +P   PG   +  SP    P +P    + + PLEP      R +A             
Sbjct: 1108 SRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPP 1167

Query: 717  PAGSRSCPLPAPTPAPFK-VGALSTEVLGRQHRAALA----------GRSLSSP------ 759
            P+G+RS   PAPT   F  +GA  +  + R+   A            GRS  SP      
Sbjct: 1168 PSGARS---PAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAG 1224

Query: 760  PGRANQVPGRPRKPSLGAILDGPSPEPGQQLGQGLDDSGNLLSPAPMDWDMLMEPPFLFT 819
            PG A     RP  P    ++  P        G+   +S +  S        L EP     
Sbjct: 1225 PGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQA 1284

Query: 820  AVPPSGELAPPAVPPQAPRCHVVI-RGLCGEQPMCWEVGVGLETLWGPGDGSQPPSPPVR 878
            A PP   L PPA   Q P   V       G QP        LET         PP PP R
Sbjct: 1285 AFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQP-------NLET---------PPQPPPR 1328



 Score = 39.3 bits (90), Expect = 0.024
 Identities = 57/231 (24%), Positives = 83/231 (35%), Gaps = 35/231 (15%)

Query: 944  ATTREVLPGALQVCSSE-----PAEPPGTPPASHSHLDAAPLPTVVY--SKGLQRG-SPA 995
            A   E+LP  LQ  SS      P+  P T P     +   P+P++    S+   R   P 
Sbjct: 1059 AEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPP 1118

Query: 996  GAWDSDQNGNSKRALG--DPATPTEGPRRPPPR---PPCRLSMGRRHKLCSPDPGQANNS 1050
             A  S  +      L   DPA P E  R PPPR   PP R +  +R     P P     S
Sbjct: 1119 SAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQR-----PPPPSGARS 1173

Query: 1051 EGSDHDYLPLVRLQEAPGSFRLDAPFCAAVRISQERLCRASPFAVHRASLSPTSASLPWA 1110
                      +    +PG  R            +E     SP    + ++  +  S    
Sbjct: 1174 PAPTRKEFGGIGAPPSPGVAR------------REMEAPKSPGTTRKDNIGRSQPSPQAG 1221

Query: 1111 LLGPGVGQGDSATASCSPSPS--SGSEGPGQVDSGR---GSDTEASEGAEG 1156
            L GPG     +A  +  P     S  +   +  +GR    S ++ SE ++G
Sbjct: 1222 LAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKG 1272



 Score = 32.3 bits (72), Expect = 2.9
 Identities = 26/83 (31%), Positives = 38/83 (45%), Gaps = 7/83 (8%)

Query: 126  AAGTMTVTLHSSRELPSR-PDGVLHVALPTVLTPLAPPGPPGPP-RPP---GLCDDSPT- 179
            +A +  +    +  LP + P   L    P    P+APP  P PP RPP   G    +PT 
Sbjct: 1119 SAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTR 1178

Query: 180  -SCFGVGSLQEEGLAWEELAAPR 201
                G+G+    G+A  E+ AP+
Sbjct: 1179 KEFGGIGAPPSPGVARREMEAPK 1201


>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 85/346 (24%), Positives = 116/346 (33%), Gaps = 63/346 (18%)

Query: 517 RKALEPALSDISVDWFVPDTVEALLTPREIPALYPGDQLLGYCSLFRVDGFRSRPPGGQE 576
           R  L P+          PD       P E+ A  P    LG  S  + D     PP    
Sbjct: 337 RLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQ-SQSQADERAGTPPPAP- 394

Query: 577 PGWQSSGGSVFPSPEEAPSAASPGTEPTGTSEPLGTGTVSAELSSPWAARDSEQSTDALT 636
                      P P  AP    P       + PL     +A    P     + +S+    
Sbjct: 395 -----------PLPPPAPPLPPPAPPLPPAAPPLPCAQKAAH--PPAGFTKTPKSSSPAL 441

Query: 637 DPVTDPGPNPSDTAI-----WRRIFQSSYIREQYVLTHCSASPE-------PGPGSTGSS 684
            P  +P P+P +TA      WR   Q   +R +     C +  E       PGP     S
Sbjct: 442 KPKPNP-PSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQS 500

Query: 685 ESPGSQGPGSPEGSAPLEPPSQQ----------GCRSLAWGEPAGSRSCP----LPAPTP 730
           +  G +GP  PE    L  P++           G  SL   E A S + P    +P  +P
Sbjct: 501 KE-GKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSP 559

Query: 731 APFKVGALSTEVLGRQHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPSPEPGQQL 790
            P            RQ R  L  R  S+    A        KPS+G++   P  E G+  
Sbjct: 560 TPSV----------RQIRNELEARLSSAAEKEA--------KPSIGSLPPKPRLEGGRIC 601

Query: 791 GQGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVPPQA 836
             G DD   L  P   +           T++ P   L  PA+PP+A
Sbjct: 602 ENGADDD-KLSKPVAKNLPPQSTTLLPTTSLQPKAMLG-PAIPPKA 645



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 55/226 (24%), Positives = 80/226 (35%), Gaps = 41/226 (18%)

Query: 921  LRALQTSKVSSAPSCFTCPVAVDATTREVLPGALQVCSSEPAEPPGTPPASHSHLDAAPL 980
            L AL      S+PS  T P        + +P A  +    P  PP   PA        P 
Sbjct: 194  LEALSPPHTLSSPSIPTPP--------DFIPPAPPLAFLAPPPPPVPAPAP-------PA 238

Query: 981  PTVVYSKGLQRGSPAGA--WDSDQNGNSKRALGDPATPTEGPRRPP-----PRPPCRLSM 1033
            P   ++ G +   P G   W SD   N ++A    A+P   P  P      P P   L+ 
Sbjct: 239  PASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTF 298

Query: 1034 GRRHKLCSPDPGQANNSEGSDHDYLPLVRLQEAP---------GSFRLDAPFCAAVRISQ 1084
             R  K+  P P + ++        +P+   QEAP            RL  P    +R + 
Sbjct: 299  PRSFKVPPPTPVRTSS--------IPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPAS 350

Query: 1085 ERLCRASPFAVHRASLSPTSASLPWALLGPGVGQGDSATASCSPSP 1130
            +     +P       L  T+ + P   LG    Q D    +  P+P
Sbjct: 351  QVYPDRAPEPDCPGELKATAPASP--RLGQSQSQADERAGTPPPAP 394



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 59/232 (25%), Positives = 73/232 (31%), Gaps = 49/232 (21%)

Query: 580 QSSGGSVFPSPEEAPSAASPGTEPTGTSEPLGTGTVSAELSSPWAARDSEQSTDALTDPV 639
           Q + G   P+P      A    E TGTS  L  G +    SS    R  +   D L  P 
Sbjct: 87  QENHGLAVPTPSVPDDFADK--EVTGTSS-LVNGNLRL-YSSVGDLRPGQYGQDLLIPP- 141

Query: 640 TDPGPNPSDTAIWRRIFQSSYIREQYVLTHCSASPEPGPGSTGSSESPGSQGPGSPEGSA 699
             PGP P                 Q +      SP P P ST     P    P  P   A
Sbjct: 142 PPPGPAPGPP--------------QDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMA 187

Query: 700 P--------LEPPSQQGCRSLAW------GEPAGSRSCPLPAPTPAPFKVGALSTEVLGR 745
           P        L PP      S+          P  +   P P P PAP      S   +G 
Sbjct: 188 PPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGT 247

Query: 746 -----------QHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPSPEP 786
                      +   AL GR   +      + P  P+  +L     GP+PEP
Sbjct: 248 RLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSAL-----GPNPEP 294



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 48/204 (23%), Positives = 67/204 (32%), Gaps = 21/204 (10%)

Query: 585 SVFPSPEEAPSAA-SPGTEPTGTSEPLGTGTVSAELSSPWAARDSEQSTDALTDPVTDPG 643
           ++ P+    P A   P   P  T EP          ++ W A   + +    T      G
Sbjct: 624 TLLPTTSLQPKAMLGPAIPPKATPEP-----AIPPKATLWPATPPKATLGPATPLKATSG 678

Query: 644 PNPSDTAIWRRIFQSSYIREQYVLTHCSASPEPGPGSTGSSESPGSQGPGSPEGSAPLEP 703
           P     A       S+        +   A  + GP   G  E P SQ   +P  +     
Sbjct: 679 PTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPA--GQPEKPASQEVSTPSQARGEGS 736

Query: 704 PSQ------QGCRSLAWGEPAGSRSCPLPAPTPAPFKV----GALSTEVLGRQHRAALAG 753
           PS+      QG RS A   P   ++ P     P  +K      +LS EV       A  G
Sbjct: 737 PSEATRLPTQGARSSAAFPP---KTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGG 793

Query: 754 RSLSSPPGRANQVPGRPRKPSLGA 777
            +    P    + PG P KP   A
Sbjct: 794 AAGPGEPVEVKEPPGLPAKPPASA 817



 Score = 31.6 bits (70), Expect = 4.9
 Identities = 35/118 (29%), Positives = 42/118 (35%), Gaps = 27/118 (22%)

Query: 724 PLPAPTPAPFKVGALSTEVLGRQHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPS 783
           P P P PAP     +S             G  L SPP  A      P  P L  +L+ P 
Sbjct: 140 PPPPPGPAPGPPQDISEPP---------GGSPLPSPPSTA------PPPPPL--LLEPPP 182

Query: 784 PE----PGQQLGQGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVPPQAP 837
           P     P   + + L     L SP+      +  PP      PP   LAPP  P  AP
Sbjct: 183 PPSMAPPPPPVLEALSPPHTLSSPS------IPTPPDFIPPAPPLAFLAPPPPPVPAP 234


>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 85/346 (24%), Positives = 116/346 (33%), Gaps = 63/346 (18%)

Query: 517 RKALEPALSDISVDWFVPDTVEALLTPREIPALYPGDQLLGYCSLFRVDGFRSRPPGGQE 576
           R  L P+          PD       P E+ A  P    LG  S  + D     PP    
Sbjct: 337 RLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQ-SQSQADERAGTPPPAP- 394

Query: 577 PGWQSSGGSVFPSPEEAPSAASPGTEPTGTSEPLGTGTVSAELSSPWAARDSEQSTDALT 636
                      P P  AP    P       + PL     +A    P     + +S+    
Sbjct: 395 -----------PLPPPAPPLPPPAPPLPPAAPPLPCAQKAAH--PPAGFTKTPKSSSPAL 441

Query: 637 DPVTDPGPNPSDTAI-----WRRIFQSSYIREQYVLTHCSASPE-------PGPGSTGSS 684
            P  +P P+P +TA      WR   Q   +R +     C +  E       PGP     S
Sbjct: 442 KPKPNP-PSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQS 500

Query: 685 ESPGSQGPGSPEGSAPLEPPSQQ----------GCRSLAWGEPAGSRSCP----LPAPTP 730
           +  G +GP  PE    L  P++           G  SL   E A S + P    +P  +P
Sbjct: 501 KE-GKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSP 559

Query: 731 APFKVGALSTEVLGRQHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPSPEPGQQL 790
            P            RQ R  L  R  S+    A        KPS+G++   P  E G+  
Sbjct: 560 TPSV----------RQIRNELEARLSSAAEKEA--------KPSIGSLPPKPRLEGGRIC 601

Query: 791 GQGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVPPQA 836
             G DD   L  P   +           T++ P   L  PA+PP+A
Sbjct: 602 ENGADDD-KLSKPVAKNLPPQSTTLLPTTSLQPKAMLG-PAIPPKA 645



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 55/226 (24%), Positives = 80/226 (35%), Gaps = 41/226 (18%)

Query: 921  LRALQTSKVSSAPSCFTCPVAVDATTREVLPGALQVCSSEPAEPPGTPPASHSHLDAAPL 980
            L AL      S+PS  T P        + +P A  +    P  PP   PA        P 
Sbjct: 194  LEALSPPHTLSSPSIPTPP--------DFIPPAPPLAFLAPPPPPVPAPAP-------PA 238

Query: 981  PTVVYSKGLQRGSPAGA--WDSDQNGNSKRALGDPATPTEGPRRPP-----PRPPCRLSM 1033
            P   ++ G +   P G   W SD   N ++A    A+P   P  P      P P   L+ 
Sbjct: 239  PASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTF 298

Query: 1034 GRRHKLCSPDPGQANNSEGSDHDYLPLVRLQEAP---------GSFRLDAPFCAAVRISQ 1084
             R  K+  P P + ++        +P+   QEAP            RL  P    +R + 
Sbjct: 299  PRSFKVPPPTPVRTSS--------IPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPAS 350

Query: 1085 ERLCRASPFAVHRASLSPTSASLPWALLGPGVGQGDSATASCSPSP 1130
            +     +P       L  T+ + P   LG    Q D    +  P+P
Sbjct: 351  QVYPDRAPEPDCPGELKATAPASP--RLGQSQSQADERAGTPPPAP 394



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 59/232 (25%), Positives = 73/232 (31%), Gaps = 49/232 (21%)

Query: 580 QSSGGSVFPSPEEAPSAASPGTEPTGTSEPLGTGTVSAELSSPWAARDSEQSTDALTDPV 639
           Q + G   P+P      A    E TGTS  L  G +    SS    R  +   D L  P 
Sbjct: 87  QENHGLAVPTPSVPDDFADK--EVTGTSS-LVNGNLRL-YSSVGDLRPGQYGQDLLIPP- 141

Query: 640 TDPGPNPSDTAIWRRIFQSSYIREQYVLTHCSASPEPGPGSTGSSESPGSQGPGSPEGSA 699
             PGP P                 Q +      SP P P ST     P    P  P   A
Sbjct: 142 PPPGPAPGPP--------------QDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMA 187

Query: 700 P--------LEPPSQQGCRSLAW------GEPAGSRSCPLPAPTPAPFKVGALSTEVLGR 745
           P        L PP      S+          P  +   P P P PAP      S   +G 
Sbjct: 188 PPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGT 247

Query: 746 -----------QHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPSPEP 786
                      +   AL GR   +      + P  P+  +L     GP+PEP
Sbjct: 248 RLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSAL-----GPNPEP 294



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 48/204 (23%), Positives = 67/204 (32%), Gaps = 21/204 (10%)

Query: 585 SVFPSPEEAPSAA-SPGTEPTGTSEPLGTGTVSAELSSPWAARDSEQSTDALTDPVTDPG 643
           ++ P+    P A   P   P  T EP          ++ W A   + +    T      G
Sbjct: 624 TLLPTTSLQPKAMLGPAIPPKATPEP-----AIPPKATLWPATPPKATLGPATPLKATSG 678

Query: 644 PNPSDTAIWRRIFQSSYIREQYVLTHCSASPEPGPGSTGSSESPGSQGPGSPEGSAPLEP 703
           P     A       S+        +   A  + GP   G  E P SQ   +P  +     
Sbjct: 679 PTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPA--GQPEKPASQEVSTPSQARGEGS 736

Query: 704 PSQ------QGCRSLAWGEPAGSRSCPLPAPTPAPFKV----GALSTEVLGRQHRAALAG 753
           PS+      QG RS A   P   ++ P     P  +K      +LS EV       A  G
Sbjct: 737 PSEATRLPTQGARSSAAFPP---KTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGG 793

Query: 754 RSLSSPPGRANQVPGRPRKPSLGA 777
            +    P    + PG P KP   A
Sbjct: 794 AAGPGEPVEVKEPPGLPAKPPASA 817



 Score = 31.6 bits (70), Expect = 4.9
 Identities = 35/118 (29%), Positives = 42/118 (35%), Gaps = 27/118 (22%)

Query: 724 PLPAPTPAPFKVGALSTEVLGRQHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPS 783
           P P P PAP     +S             G  L SPP  A      P  P L  +L+ P 
Sbjct: 140 PPPPPGPAPGPPQDISEPP---------GGSPLPSPPSTA------PPPPPL--LLEPPP 182

Query: 784 PE----PGQQLGQGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVPPQAP 837
           P     P   + + L     L SP+      +  PP      PP   LAPP  P  AP
Sbjct: 183 PPSMAPPPPPVLEALSPPHTLSSPS------IPTPPDFIPPAPPLAFLAPPPPPVPAP 234


>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
           sapiens]
          Length = 1188

 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 85/346 (24%), Positives = 116/346 (33%), Gaps = 63/346 (18%)

Query: 517 RKALEPALSDISVDWFVPDTVEALLTPREIPALYPGDQLLGYCSLFRVDGFRSRPPGGQE 576
           R  L P+          PD       P E+ A  P    LG  S  + D     PP    
Sbjct: 337 RLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQ-SQSQADERAGTPPPAP- 394

Query: 577 PGWQSSGGSVFPSPEEAPSAASPGTEPTGTSEPLGTGTVSAELSSPWAARDSEQSTDALT 636
                      P P  AP    P       + PL     +A    P     + +S+    
Sbjct: 395 -----------PLPPPAPPLPPPAPPLPPAAPPLPCAQKAAH--PPAGFTKTPKSSSPAL 441

Query: 637 DPVTDPGPNPSDTAI-----WRRIFQSSYIREQYVLTHCSASPE-------PGPGSTGSS 684
            P  +P P+P +TA      WR   Q   +R +     C +  E       PGP     S
Sbjct: 442 KPKPNP-PSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQS 500

Query: 685 ESPGSQGPGSPEGSAPLEPPSQQ----------GCRSLAWGEPAGSRSCP----LPAPTP 730
           +  G +GP  PE    L  P++           G  SL   E A S + P    +P  +P
Sbjct: 501 KE-GKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSP 559

Query: 731 APFKVGALSTEVLGRQHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPSPEPGQQL 790
            P            RQ R  L  R  S+    A        KPS+G++   P  E G+  
Sbjct: 560 TPSV----------RQIRNELEARLSSAAEKEA--------KPSIGSLPPKPRLEGGRIC 601

Query: 791 GQGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVPPQA 836
             G DD   L  P   +           T++ P   L  PA+PP+A
Sbjct: 602 ENGADDD-KLSKPVAKNLPPQSTTLLPTTSLQPKAMLG-PAIPPKA 645



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 55/226 (24%), Positives = 80/226 (35%), Gaps = 41/226 (18%)

Query: 921  LRALQTSKVSSAPSCFTCPVAVDATTREVLPGALQVCSSEPAEPPGTPPASHSHLDAAPL 980
            L AL      S+PS  T P        + +P A  +    P  PP   PA        P 
Sbjct: 194  LEALSPPHTLSSPSIPTPP--------DFIPPAPPLAFLAPPPPPVPAPAP-------PA 238

Query: 981  PTVVYSKGLQRGSPAGA--WDSDQNGNSKRALGDPATPTEGPRRPP-----PRPPCRLSM 1033
            P   ++ G +   P G   W SD   N ++A    A+P   P  P      P P   L+ 
Sbjct: 239  PASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTF 298

Query: 1034 GRRHKLCSPDPGQANNSEGSDHDYLPLVRLQEAP---------GSFRLDAPFCAAVRISQ 1084
             R  K+  P P + ++        +P+   QEAP            RL  P    +R + 
Sbjct: 299  PRSFKVPPPTPVRTSS--------IPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPAS 350

Query: 1085 ERLCRASPFAVHRASLSPTSASLPWALLGPGVGQGDSATASCSPSP 1130
            +     +P       L  T+ + P   LG    Q D    +  P+P
Sbjct: 351  QVYPDRAPEPDCPGELKATAPASP--RLGQSQSQADERAGTPPPAP 394



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 59/232 (25%), Positives = 73/232 (31%), Gaps = 49/232 (21%)

Query: 580 QSSGGSVFPSPEEAPSAASPGTEPTGTSEPLGTGTVSAELSSPWAARDSEQSTDALTDPV 639
           Q + G   P+P      A    E TGTS  L  G +    SS    R  +   D L  P 
Sbjct: 87  QENHGLAVPTPSVPDDFADK--EVTGTSS-LVNGNLRL-YSSVGDLRPGQYGQDLLIPP- 141

Query: 640 TDPGPNPSDTAIWRRIFQSSYIREQYVLTHCSASPEPGPGSTGSSESPGSQGPGSPEGSA 699
             PGP P                 Q +      SP P P ST     P    P  P   A
Sbjct: 142 PPPGPAPGPP--------------QDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMA 187

Query: 700 P--------LEPPSQQGCRSLAW------GEPAGSRSCPLPAPTPAPFKVGALSTEVLGR 745
           P        L PP      S+          P  +   P P P PAP      S   +G 
Sbjct: 188 PPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGT 247

Query: 746 -----------QHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPSPEP 786
                      +   AL GR   +      + P  P+  +L     GP+PEP
Sbjct: 248 RLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSAL-----GPNPEP 294



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 48/204 (23%), Positives = 67/204 (32%), Gaps = 21/204 (10%)

Query: 585 SVFPSPEEAPSAA-SPGTEPTGTSEPLGTGTVSAELSSPWAARDSEQSTDALTDPVTDPG 643
           ++ P+    P A   P   P  T EP          ++ W A   + +    T      G
Sbjct: 624 TLLPTTSLQPKAMLGPAIPPKATPEP-----AIPPKATLWPATPPKATLGPATPLKATSG 678

Query: 644 PNPSDTAIWRRIFQSSYIREQYVLTHCSASPEPGPGSTGSSESPGSQGPGSPEGSAPLEP 703
           P     A       S+        +   A  + GP   G  E P SQ   +P  +     
Sbjct: 679 PTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPA--GQPEKPASQEVSTPSQARGEGS 736

Query: 704 PSQ------QGCRSLAWGEPAGSRSCPLPAPTPAPFKV----GALSTEVLGRQHRAALAG 753
           PS+      QG RS A   P   ++ P     P  +K      +LS EV       A  G
Sbjct: 737 PSEATRLPTQGARSSAAFPP---KTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGG 793

Query: 754 RSLSSPPGRANQVPGRPRKPSLGA 777
            +    P    + PG P KP   A
Sbjct: 794 AAGPGEPVEVKEPPGLPAKPPASA 817



 Score = 31.6 bits (70), Expect = 4.9
 Identities = 35/118 (29%), Positives = 42/118 (35%), Gaps = 27/118 (22%)

Query: 724 PLPAPTPAPFKVGALSTEVLGRQHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPS 783
           P P P PAP     +S             G  L SPP  A      P  P L  +L+ P 
Sbjct: 140 PPPPPGPAPGPPQDISEPP---------GGSPLPSPPSTA------PPPPPL--LLEPPP 182

Query: 784 PE----PGQQLGQGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVPPQAP 837
           P     P   + + L     L SP+      +  PP      PP   LAPP  P  AP
Sbjct: 183 PPSMAPPPPPVLEALSPPHTLSSPS------IPTPPDFIPPAPPLAFLAPPPPPVPAP 234


>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
          Length = 1526

 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 66/241 (27%), Positives = 78/241 (32%), Gaps = 41/241 (17%)

Query: 663  EQYVLTHCSASPEPGPGSTGSSESPGS--QGPGSPEGSAPLEPPSQQGCRSLAWGEPAGS 720
            E+ +  H   S   G G++ SS    S  Q P   EG  P  P       S   G P+  
Sbjct: 1018 EELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQ 1077

Query: 721  RS-------CPLPAPTPA---------PFKVGALSTEVLGRQHRAALAGRSLSSP----- 759
             S        PLP   PA         P +  A  T     Q     +GRS  SP     
Sbjct: 1078 SSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGLA 1137

Query: 760  -PGRANQVPGRPRKPSLGAILDGPSPEPGQQLGQGLDDSGNLLSPAPMDWDMLMEPPFLF 818
             PG A     RP  P    ++  P        G+   +S +  S        L EP    
Sbjct: 1138 GPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQ 1197

Query: 819  TAVPPSGELAPPAVPPQAPRCHVVI-RGLCGEQPMCWEVGVGLETLWGPGDGSQPPSPPV 877
             A PP   L PPA   Q P   V       G QP        LET         PP PP 
Sbjct: 1198 AAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQP-------NLET---------PPQPPP 1241

Query: 878  R 878
            R
Sbjct: 1242 R 1242



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 31/94 (32%), Positives = 39/94 (41%), Gaps = 10/94 (10%)

Query: 944  ATTREVLPGALQVCSSE-----PAEPPGTPPASHSHLDAAPLPTVVY--SKGLQRG-SPA 995
            A   E+LP  LQ  SS      P+  P T P     +   P+P++    S+   R   P 
Sbjct: 1015 AEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPP 1074

Query: 996  GAWDSDQNGNSKRALG--DPATPTEGPRRPPPRP 1027
             A  S  +      L   DPA P E  R PPPRP
Sbjct: 1075 SAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRP 1108


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 87/319 (27%), Positives = 109/319 (34%), Gaps = 43/319 (13%)

Query: 592 EAPSAASPGTEPTGTSEPLGTGTVSAELSSPWAARDSEQSTD----ALTDPVTDPG-PNP 646
           EA  A SPG  P G   P G      E   P  A  + Q  D    AL  P  + G P P
Sbjct: 606 EAGPAGSPG--PPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGP 663

Query: 647 SDTAIWRRIFQSSYIREQYVLTHCSASPEPG-PGSTGS---SESPGSQGPGSP---EGSA 699
               +  +  ++     +          +PG PG+TG    S  PG QGP  P   +G  
Sbjct: 664 PGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDG 723

Query: 700 PLEPPSQQGCRSLAWGEPA--GSRSCPLPAPTPAPFKVGALSTEVLGRQHRAALAG-RSL 756
               PS QG  +   G P   G +    P     P K G     + G Q    L G +  
Sbjct: 724 CTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPG--QPGLPGVQGPPGLKGVQGE 781

Query: 757 SSPPGRANQVP-GRPRKPSLGAI--LDGPSPEPGQQLGQGLDDSGNLLSPAPMDWDMLME 813
             PPGR  Q P G P  P L  I  L GP   PG        + G   SP        + 
Sbjct: 782 PGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGP-----TGEKGAQGSPGVKGATGPVG 836

Query: 814 PPFLFTAVPPS--------------GELAPPAVPPQAPRCHVVIRGLCGEQPMCWEVGVG 859
           PP    + PP               GE  P     +   C    +G      M    G+ 
Sbjct: 837 PPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLW 896

Query: 860 LETLWGPGDGSQP--PSPP 876
           + + W PG    P  P PP
Sbjct: 897 MGSSWQPGPQGPPGIPGPP 915



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 56/216 (25%), Positives = 71/216 (32%), Gaps = 38/216 (17%)

Query: 674  PEPGPGSTGSSESPGSQGPGSPEGSAPLEPPSQQGCRSLAWGEPAGSRSCPLPAPTPAPF 733
            P   PG  G   SPG  GP + +GS  +  PS         G P GS   P P     P 
Sbjct: 1163 PPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPS---------GLP-GSPGPPGPPGIQGPA 1212

Query: 734  KVGALSTEVLGRQHRAALAG-------RSLSSPPGRANQVPGRPRKPSLGAILDGPSPEP 786
             +  L     G+  +  L G         L  PPG   +  G P  P        P P P
Sbjct: 1213 GLDGLD----GKDGKPGLRGDPGPAGPPGLMGPPGFKGKT-GHPGLPGPKGDCGKPGP-P 1266

Query: 787  GQQLGQGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVPPQAPRCHVVIRGL 846
            G     G +     + P                   P G + PP  P Q     +   GL
Sbjct: 1267 GSTGRPGAEGEPGAMGPQGRP--------------GPPGHVGPPGPPGQPGPAGISAVGL 1312

Query: 847  CGEQPMCWEVGV-GLETLWGPGDGSQPPSPPVREAA 881
             G++    E G+ GL    GP     PP  P  + A
Sbjct: 1313 KGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGA 1348



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 64/236 (27%), Positives = 86/236 (36%), Gaps = 51/236 (21%)

Query: 676 PGP-GSTGSSESPGSQGPGSPEGSAPLE----------PPSQQGCRSLAW--GEPAGSRS 722
           PGP G  GSS  PG +GPG   G   ++          P   +G ++     G+P     
Sbjct: 473 PGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGE 532

Query: 723 CPLPAPTPAPFKVGALSTE----------VLGRQHRAALAGRS--LSSP-------PGRA 763
              P P      +  +  E          V+G QH  +  G S  + SP       PGRA
Sbjct: 533 PGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRA 592

Query: 764 NQVPG-RPRKPSLGAILDGPSPEPGQQLG-QGLDDS-GNLLSPAPMDWDMLMEPPFLFTA 820
             VPG +  K + G      SP P   +G  G+  + G    P P     L +      A
Sbjct: 593 G-VPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPA-LSNLQDGDVRVVA 650

Query: 821 VP-PSGELAPPAVPPQAPRCHVVIRGLCGEQPMCWEVGVGLETLWGPGDGSQPPSP 875
           +P PSGE   P  P           GL G+Q    E G+  +     GD   P  P
Sbjct: 651 LPGPSGEKGEPGPPG---------FGLPGKQGKAGERGLKGQ----KGDAGNPGDP 693



 Score = 35.8 bits (81), Expect = 0.26
 Identities = 33/111 (29%), Positives = 44/111 (39%), Gaps = 4/111 (3%)

Query: 679 GSTGSSESPGSQGPGSPEGSAPLEPPSQQGCRSLAWGEPAGSRSCPLPAPTPAPFKVGAL 738
           G  G + SPG  GP  P G    +    + C +L+  +    R   LP P+    + G  
Sbjct: 605 GEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPP 664

Query: 739 STEVLGRQHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILDGPSPEPGQQ 789
              + G+Q +A    R L    G A   PG P  P       G S EPG Q
Sbjct: 665 GFGLPGKQGKA--GERGLKGQKGDAGN-PGDPGTPGTTG-RPGLSGEPGVQ 711



 Score = 32.0 bits (71), Expect = 3.8
 Identities = 56/204 (27%), Positives = 70/204 (34%), Gaps = 49/204 (24%)

Query: 670  CSASP----EPG-PGSTGSSESPGSQGPGSPEGSAPLEP------------PSQQGCRSL 712
            C  SP     PG PG  G    PG +G   P G  P+ P            P  QG R L
Sbjct: 1016 CVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPG--PIGPPGFPGAVGSPGLPGLQGERGL 1073

Query: 713  AW-----GEPAGSRSCPLPAPTPAPFKVGALSTEVLGRQHRAALAGRSLSSPPGRANQVP 767
                   GEP        P  T  P   G     + G +     AG      P  +  +P
Sbjct: 1074 TGLTGDKGEPGPPGQPGYPGATGPPGLPG-----IKGERGYTGSAGEKGEPGPPGSEGLP 1128

Query: 768  GRPRKPSLGAILDGPSPEPGQQLGQGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPS--G 825
            G P          GP+   G++  QG  +SG        D     +P F     PP   G
Sbjct: 1129 GPP----------GPAGPRGERGPQG--NSGE-----KGDQGFQGQPGFPGPPGPPGFPG 1171

Query: 826  ELAPPAVP-PQAPRCHVVIRGLCG 848
            ++  P  P PQA +    IRG  G
Sbjct: 1172 KVGSPGPPGPQAEKGSEGIRGPSG 1195



 Score = 32.0 bits (71), Expect = 3.8
 Identities = 22/64 (34%), Positives = 24/64 (37%), Gaps = 5/64 (7%)

Query: 153  PTVLTPLAPPGPPG---PPRPPGLCDDSPTSCFGVGSLQEEGLAWEELAAPRDVFSGPAR 209
            P  + P   PGPPG   PP PPG     P     VG   + G   E   A      GP  
Sbjct: 1278 PGAMGPQGRPGPPGHVGPPGPPG--QPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPG 1335

Query: 210  CPAP 213
             P P
Sbjct: 1336 HPGP 1339



 Score = 30.8 bits (68), Expect = 8.4
 Identities = 11/16 (68%), Positives = 12/16 (75%)

Query: 158 PLAPPGPPGPPRPPGL 173
           P  PPG PGPP PPG+
Sbjct: 905 PQGPPGIPGPPGPPGV 920


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 55/219 (25%), Positives = 79/219 (36%), Gaps = 20/219 (9%)

Query: 568 RSRPPGGQEPGWQSSGGSVFPSPEEAPSAASPGTEP--TGTSEPLGTGTVSAELSSPWAA 625
           RSR    +      +G S  P+        +P +EP  T T  P    T + + SSP+  
Sbjct: 278 RSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYED 337

Query: 626 RDSEQSTDALTDPVTDP-----GPNPSDTAIWRRIFQSSYIREQYVLTHCSASPEPGPGS 680
           +D ++   + T P   P     GP P        +    +      L     S EP    
Sbjct: 338 KDKDKKEKSATRPSPSPERSSTGPEPPAPT---PLLAERHGGSPQPLATTPLSQEPVNPP 394

Query: 681 TGSSESPGSQGPGSPE-----GSAPLEPPSQQGCRSLAWGEPAGSRSCPLPAPTPAPFKV 735
           + +S +     P SPE      S+   PPS Q  +       + S   P PAP P   + 
Sbjct: 395 SEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSR--HASSSPESPKPAPAPGSHRE 452

Query: 736 GALSTEVLGRQHRAALAGRSLSSPPGRANQVPGRPRKPS 774
            + S     R H  A   +S S  P R     GR R P+
Sbjct: 453 ISSSPTSKNRSHGRAKRDKSHSHTPSRR---MGRSRSPA 488



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 45/134 (33%), Positives = 62/134 (46%), Gaps = 31/134 (23%)

Query: 672  ASPEPG-------PGSTGSSESPGSQGPGSPEGSA-----PLEPPSQQGCRSLAWGEPAG 719
            +SPEP        P  + S  S   +GP SPEGS+     P  PP  +  R        G
Sbjct: 1620 SSPEPKAPAPRALPRRSRSGSSSKGRGP-SPEGSSSTESSPEHPPKSRTAR-------RG 1671

Query: 720  SRSCPLP---APTPAPFKVGALSTEVLGRQHRAALAGRSLSSPPGRANQVPGRPRK-PSL 775
            SRS P P   + TP P +  + S+  L R+ R +   RS SS P   ++ P R R+ PS+
Sbjct: 1672 SRSSPEPKTKSRTP-PRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSV 1730

Query: 776  GAILDGPSPEPGQQ 789
                   SPEP ++
Sbjct: 1731 S------SPEPAEK 1738



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 46/190 (24%), Positives = 74/190 (38%), Gaps = 33/190 (17%)

Query: 588  PSPEEAPSAASPGTEPTGTSEPLGTGTVSAELSSPWAARDSEQSTDALTDPVTDPGPNPS 647
            P+P+EA     P  EPT       + + S+  SS  ++  S  S+ + +   +    + S
Sbjct: 2584 PAPKEAVREGRP-PEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642

Query: 648  DTAIWRRIFQSSYIREQYVLTHCSASP---EPGPGSTGSSESPGSQGPGSPEGSAPLEP- 703
             ++                    S+SP   +PGP +     SP    PG     +P +P 
Sbjct: 2643 SSS--------------------SSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPI 2682

Query: 704  PSQQGCRSLAWGEPAGSRSCPLPAPTPAPFKVGALSTEVLGRQHRAALAGRSLSSPPGRA 763
             S +  RSL++      R    P+P P+P    + S+E   R  R    G S S    R 
Sbjct: 2683 DSLRDSRSLSYSPVERRR----PSPQPSPRDQQSSSSE---RGSRRGQRGDSRSPSHKRR 2735

Query: 764  NQVPG-RPRK 772
             + P  RP +
Sbjct: 2736 RETPSPRPMR 2745



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 48/218 (22%), Positives = 81/218 (37%), Gaps = 19/218 (8%)

Query: 958  SSEPAEPPGTPPASHSHLDAAPLPTVVYSKGLQRGSPAGAWDSDQNGN-SKRALGDPATP 1016
            SS P +     P+  SH  ++P P V      ++GS      ++Q+    +R+  + +  
Sbjct: 819  SSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPD 878

Query: 1017 TEGPRRPPPRPPCRLSMGRRHKLCSPDPGQANNSEGSDHDYLPLV--RLQEAPGSFRLDA 1074
             E   R P R  C  S   R K  +P P Q+ +   S    +  +    Q +       +
Sbjct: 879  PELKSRTPSRHSCSGSSPPRVKSSTP-PRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPS 937

Query: 1075 PFCAAVRISQERLCRASPFAVHRASLSP----TSASLPWALLGPGVGQGDSATASCSPSP 1130
            P     R +  R    SP +   + L P    + +S P   + P      S + S SP P
Sbjct: 938  PSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYP 997

Query: 1131 S-----------SGSEGPGQVDSGRGSDTEASEGAEGL 1157
                        SGS+ P   +  + S  ++  G+  L
Sbjct: 998  KVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSL 1035



 Score = 32.0 bits (71), Expect = 3.8
 Identities = 39/178 (21%), Positives = 59/178 (33%), Gaps = 31/178 (17%)

Query: 570  RPPGGQEPGWQSSGGSVFPSPEEAPSAASPG------------TEPTGTSEPLGTGTVSA 617
            R P       Q+   S+ P  ++ P +  P             T P   S+ L +G V+ 
Sbjct: 2423 RAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVAT 2482

Query: 618  ELSSPWAARDSEQSTDALTDPVTDPGPNPSDTAIWR-----RIFQSSYIREQYVLTHCSA 672
              SS     +   S  A   P +D G  P+ T   +      +  +   R     +  S+
Sbjct: 2483 TTSSA-GDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSS 2541

Query: 673  SPEPGPGSTGSSESPGSQGPGSPEGSAPLEPPSQQGCRSLAWGEPAGSRSCPLPAPTP 730
            S      S+ SS S GS    S   S P++P                 +  P P P P
Sbjct: 2542 SSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPE-------------VALKRVPSPTPAP 2586


>gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo
            sapiens]
          Length = 1724

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 58/238 (24%), Positives = 100/238 (42%), Gaps = 22/238 (9%)

Query: 335  LSFCPDLSSKPGHLGTATRELLFLLDSSS-------VAHKDAIVLAVKSLPPQTLINLAV 387
            L F PDL      L + + E++  LD SS       +  K   + A+  +  +  +N+  
Sbjct: 858  LVFQPDLDVDLPDLASES-EVIICLDCSSSMEGVTFLQAKQIALHALSLVGEKQKVNIIQ 916

Query: 388  FGTLVQPLFPESRPCSDDAVQLICESIETLQVPSGPPDVLAALDWAVGQPQHRAYPRQ-- 445
            FGT  + LF  S P    +  +  E I +     G  D      W   +     YP +  
Sbjct: 917  FGTGYKELF--SYPKHITSNTMAAEFIMSATPTMGNTDF-----WKTLRYLSLLYPARGS 969

Query: 446  LFLLTAASPMAATTHRTLELMRWHRGTARCFSFGLGPTCHQ-LLQGLSALSRG--QAYFL 502
              +L  +         TL+L++  R   R F+ G+G T ++ +L+ LS    G  + +  
Sbjct: 970  RNILLVSDGHLQDESLTLQLVKRSRPHTRLFACGIGSTANRHVLRILSQCGAGVFEYFNA 1029

Query: 503  RPGQRLQPMLVQALRKALEPALSDISVDW--FVPDTVEALLTPREIPALYPGDQLLGY 558
            +     +  +   + +   P+   +SV W    PD  EAL  P ++P+L+  D+LL Y
Sbjct: 1030 KSKHSWRKQIEDQMTRLCSPSCHSVSVKWQQLNPDVPEALQAPAQVPSLFLNDRLLVY 1087



 Score = 37.7 bits (86), Expect = 0.069
 Identities = 20/82 (24%), Positives = 37/82 (45%)

Query: 13  LPLTDSWVRACANGPCLSVRARLTYRNPQPQPVDGVFVYPLAEAEVVSGFEAEAAGRRVS 72
           +PL D  ++         V    TY N    P++  +++PL +   V GFEA   G+ + 
Sbjct: 621 VPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFPLDDKAAVCGFEAFINGKHIV 680

Query: 73  FQLQSRRRSQAACCRALGPGLG 94
            +++ +  +Q     A+  G G
Sbjct: 681 GEIKEKEEAQQEYLEAVTQGHG 702


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,082,592
Number of Sequences: 37866
Number of extensions: 4128943
Number of successful extensions: 38749
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 102
Number of HSP's successfully gapped in prelim test: 991
Number of HSP's that attempted gapping in prelim test: 25039
Number of HSP's gapped (non-prelim): 13095
length of query: 1242
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1128
effective length of database: 13,930,794
effective search space: 15713935632
effective search space used: 15713935632
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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