Guide to the Human Genome
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Search of human proteins with 115298672

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|115298672 neutrophil cytosolic factor 1 [Homo sapiens]
         (390 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|115298672 neutrophil cytosolic factor 1 [Homo sapiens]             798   0.0  
gi|55749544 SH3 multiple domains 1 [Homo sapiens]                     208   8e-54
gi|63055059 SH3 and PX domains 2B [Homo sapiens]                      207   1e-53
gi|41281828 NADPH oxidase organizer 1 isoform c [Homo sapiens]        106   3e-23
gi|41281811 NADPH oxidase organizer 1 isoform b [Homo sapiens]        106   3e-23
gi|21389405 NADPH oxidase organizer 1 isoform a [Homo sapiens]        102   6e-22
gi|239752628 PREDICTED: hypothetical protein XP_002347816 [Homo ...    85   1e-16
gi|194294523 intersectin 2 isoform 3 [Homo sapiens]                    73   4e-13
gi|194294521 intersectin 2 isoform 1 [Homo sapiens]                    73   4e-13
gi|194294525 intersectin 2 isoform 2 [Homo sapiens]                    73   4e-13
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]                63   5e-10
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]                63   5e-10
gi|47519798 neutrophil cytosolic factor 4 isoform 1 [Homo sapiens]     58   2e-08
gi|163644267 neutrophil cytosolic factor 4 isoform 2 [Homo sapiens]    58   2e-08
gi|20149528 proline-serine-threonine phosphatase interacting pro...    57   3e-08
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H...    55   8e-08
gi|89886447 nitric oxide synthase trafficker isoform 2 [Homo sap...    54   2e-07
gi|16418431 nitric oxide synthase trafficker isoform 1 [Homo sap...    54   2e-07
gi|11321634 CD2-associated protein [Homo sapiens]                      51   2e-06
gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo ...    51   2e-06
gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo ...    51   2e-06
gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo ...    51   2e-06
gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo ...    51   2e-06
gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo ...    51   2e-06
gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo ...    51   2e-06
gi|10947118 sorbin and SH3 domain containing 2 isoform 2 [Homo s...    51   2e-06
gi|194733749 sorbin and SH3 domain containing 2 isoform 1 [Homo ...    51   2e-06
gi|166064038 PAK-interacting exchange factor beta isoform a [Hom...    50   3e-06
gi|166064036 PAK-interacting exchange factor beta isoform d [Hom...    50   3e-06
gi|166064034 PAK-interacting exchange factor beta isoform c [Hom...    50   3e-06

>gi|115298672 neutrophil cytosolic factor 1 [Homo sapiens]
          Length = 390

 Score =  798 bits (2061), Expect = 0.0
 Identities = 390/390 (100%), Positives = 390/390 (100%)

Query: 1   MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPI 60
           MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPI
Sbjct: 1   MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPI 60

Query: 61  EAGAINPENRIIPHLPAPKWFDGQRAAENRQGTLTEYCGTLMSLPTKISRCPHLLDFFKV 120
           EAGAINPENRIIPHLPAPKWFDGQRAAENRQGTLTEYCGTLMSLPTKISRCPHLLDFFKV
Sbjct: 61  EAGAINPENRIIPHLPAPKWFDGQRAAENRQGTLTEYCGTLMSLPTKISRCPHLLDFFKV 120

Query: 121 RPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALSTG 180
           RPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALSTG
Sbjct: 121 RPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALSTG 180

Query: 181 DVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAV 240
           DVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAV
Sbjct: 181 DVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAV 240

Query: 241 EGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPP 300
           EGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPP
Sbjct: 241 EGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPP 300

Query: 301 RRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSK 360
           RRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSK
Sbjct: 301 RRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSK 360

Query: 361 PQPAVPPRPSADLILNRCSESTKRKLASAV 390
           PQPAVPPRPSADLILNRCSESTKRKLASAV
Sbjct: 361 PQPAVPPRPSADLILNRCSESTKRKLASAV 390


>gi|55749544 SH3 multiple domains 1 [Homo sapiens]
          Length = 1105

 Score =  208 bits (529), Expect = 8e-54
 Identities = 106/301 (35%), Positives = 171/301 (56%), Gaps = 12/301 (3%)

Query: 6   IRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPIEAGAI 65
           ++   ++  EKR  PS+HYVY+  V W D + + +YRR+++ ++    L + FPIE G  
Sbjct: 6   VQDATVVDVEKRRNPSKHYVYIINVTWSDSTSQTIYRRYSKFFDLQMQLLDKFPIEGGQK 65

Query: 66  NPENRIIPHLPAPKWFDGQR---AAENRQGTLTEYCGTLMSLPTKISRCPHLLDFFKVRP 122
           +P+ RIIP LP    F        A  R   + EYC  L+ LP  IS+C  +  FF+ RP
Sbjct: 66  DPKQRIIPFLPGKILFRRSHIRDVAVKRLKPIDEYCRALVRLPPHISQCDEVFRFFEARP 125

Query: 123 DDLKLPTDNQ-TKKPETYLMPKDGKSTATDITG------PIILQTYRAIANYEKTSGSEM 175
           +D+  P ++  + K ++  +    +S   D+TG      P+IL+ Y  ++NY+K   SE+
Sbjct: 126 EDVNPPKEDYGSSKRKSVWLSSWAESPKKDVTGADATAEPMILEQYVVVSNYKKQENSEL 185

Query: 176 ALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAG--EPYVA 233
           +L  G+VV+V+EK+ESGWWF     ++GW+PA++LE  +   +  D   +  G  E YV 
Sbjct: 186 SLQAGEVVDVIEKNESGWWFVSTSEEQGWVPATYLEAQNGTRDDSDINTSKTGEEEKYVT 245

Query: 234 IKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQ 293
           ++ YT+   DE+   +G  VEVI K L+GWW IR     G+ P+ YL+K+  D+   ++ 
Sbjct: 246 VQPYTSQSKDEIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPASYLKKAKDDLPTRKKN 305

Query: 294 I 294
           +
Sbjct: 306 L 306



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 4/66 (6%)

Query: 160 TYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDET 219
           +Y   + Y+K   SE++   G  V+V+EK ESGWW+ +     GW P+ +L      DE 
Sbjct: 816 SYMTCSAYQKVQDSEISFPAGVEVQVLEKQESGWWYVRFGELEGWAPSHYL----VLDEN 871

Query: 220 EDPEPN 225
           E P+P+
Sbjct: 872 EQPDPS 877



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 23/99 (23%), Positives = 43/99 (43%)

Query: 119 KVRPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALS 178
           ++ P   ++ + N   +P        G         P +   Y  IA ++      ++  
Sbjct: 383 RIAPQRAQISSPNLRTRPPPRRESSLGFQLPKPPEPPSVEVEYYTIAEFQSCISDGISFR 442

Query: 179 TGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPD 217
            G   EV++K+  GWW+ Q+  K GW PAS+++    P+
Sbjct: 443 GGQKAEVIDKNSGGWWYVQIGEKEGWAPASYIDKRKKPN 481



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 22/58 (37%), Positives = 40/58 (68%), Gaps = 11/58 (18%)

Query: 161  YRAIANYE---KTSGSEMALSTGDVVEVVEKSESGWWFCQ----MKAKRGWIPASFLE 211
            Y +IA+YE   +T+G +  +S    +EV+E++ +GWW+CQ    +K  +GW+P+++LE
Sbjct: 1049 YVSIADYEGDEETAGFQEGVS----MEVLERNPNGWWYCQILDGVKPFKGWVPSNYLE 1102



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 5/69 (7%)

Query: 212 PLDSPDETEDPEPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDV 271
           P  +  E E P  +Y     +   AY  V+  E+S   G  V+V+ K   GWW +R  ++
Sbjct: 803 PCPTKKEWEGPATSY-----MTCSAYQKVQDSEISFPAGVEVQVLEKQESGWWYVRFGEL 857

Query: 272 TGYFPSMYL 280
            G+ PS YL
Sbjct: 858 EGWAPSHYL 866



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 40/162 (24%), Positives = 69/162 (42%), Gaps = 11/162 (6%)

Query: 222 PEPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQ 281
           PEP      Y  I  + +   D +S   G+  EVI K   GWW ++  +  G+ P+ Y+ 
Sbjct: 416 PEPPSVEVEYYTIAEFQSCISDGISFRGGQKAEVIDKNSGGWWYVQIGEKEGWAPASYID 475

Query: 282 KSGQ-DVSQAQRQIKR-GAPPRRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQA 339
           K  + ++S+    + R   PP     +   +    +    SQD+ R+  +++ +      
Sbjct: 476 KRKKPNLSRRTSTLTRPKVPPPAPPSKPKEAEEGPTGASESQDSPRK--LKYEEPEYDIP 533

Query: 340 RPG----PQSPGSPLEEERQTQRSKPQPAVPPRPSADLILNR 377
             G    P+    P+E+    +R   +PA P RPS    L R
Sbjct: 534 AFGFDSEPELSEEPVEDRASGER---RPAQPHRPSPASSLQR 572



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 31/91 (34%), Positives = 44/91 (48%), Gaps = 11/91 (12%)

Query: 198  MKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAVEGDE--VSLLEGEAVEV 255
            + A+R  IP S + P   P E      N   + YV+I  Y   EGDE      EG ++EV
Sbjct: 1018 LPAQRNSIPVSPVRP--KPIEKSQFIHNNLKDVYVSIADY---EGDEETAGFQEGVSMEV 1072

Query: 256  IHKLLDGWWVIRKDD----VTGYFPSMYLQK 282
            + +  +GWW  +  D      G+ PS YL+K
Sbjct: 1073 LERNPNGWWYCQILDGVKPFKGWVPSNYLEK 1103


>gi|63055059 SH3 and PX domains 2B [Homo sapiens]
          Length = 911

 Score =  207 bits (527), Expect = 1e-53
 Identities = 133/381 (34%), Positives = 196/381 (51%), Gaps = 37/381 (9%)

Query: 6   IRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPIEAGAI 65
           I  + +L  +KR VP++HYVY+  V W   S + +YRR+++ ++    + + FP+E G  
Sbjct: 7   IVEVKVLDVQKRRVPNKHYVYIIRVTWSSGSTEAIYRRYSKFFDLQMQMLDKFPMEGGQK 66

Query: 66  NPENRIIPHLPAPKWFDGQR---AAENRQGTLTEYCGTLMSLPTKISRCPHLLDFFKVRP 122
           +P+ RIIP LP    F        A  R   + EYC  L+ LP  IS+C  +L FF+ RP
Sbjct: 67  DPKQRIIPFLPGKILFRRSHIRDVAVKRLIPIDEYCKALIQLPPYISQCDEVLQFFETRP 126

Query: 123 DDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALSTGDV 182
           +DL  P +    K ++      G  T+ D   P++L+ Y  +ANY+K   SE++LS G V
Sbjct: 127 EDLNPPKEEHIGKKKS-----GGDQTSVD---PMVLEQYVVVANYQKQESSEISLSVGQV 178

Query: 183 VEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAVEG 242
           V+++EK+ESGWWF     ++GW+PA+ LE  D   +    +P    E Y  I  YTA + 
Sbjct: 179 VDIIEKNESGWWFVSTAEEQGWVPATCLEGQDGVQDEFSLQPE-EEEKYTVIYPYTARDQ 237

Query: 243 DEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQK-SGQDVSQAQRQIKRGAPPR 301
           DE++L  G  VEVI K L+GWW IR     G+ P+ YL+K SG+ +       K G  P 
Sbjct: 238 DEMNLERGAVVEVIQKNLEGWWKIRYQGKEGWAPASYLKKNSGEPLPP-----KPG--PG 290

Query: 302 RSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQR--RRQARPGPQSPG---SPLEEERQT 356
             S   A  +   SR+   Q+A  R       QR  R + RP P       SP   +R  
Sbjct: 291 SPSHPGALDLDGVSRQ---QNAVGREKELLSSQRDGRFEGRPVPDGDAKQRSPKMRQRPP 347

Query: 357 QR---------SKPQPAVPPR 368
            R         + P+P +PP+
Sbjct: 348 PRRDMTIPRGLNLPKPPIPPQ 368



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 54/225 (24%), Positives = 95/225 (42%), Gaps = 25/225 (11%)

Query: 155 PIILQTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLD 214
           P + + Y  IA ++ T    ++   G  VEV+EK+ SGWW+ Q++ K GW PA+F++   
Sbjct: 367 PQVEEEYYTIAEFQTTIPDGISFQAGLKVEVIEKNLSGWWYIQIEDKEGWAPATFIDKYK 426

Query: 215 SPDETEDPE---PNYAGEPYVAIKAYTAVEGDEVSLLEGEA---VEVIHKLLDG---W-- 263
                  P    P       + +    A+E +  S   G +    +  H ++D    W  
Sbjct: 427 KTSNASRPNFLAPLPHEVTQLRLGEAAALENNTGSEATGPSRPLPDAPHGVMDSGLPWSK 486

Query: 264 -WVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPPRRSS-IRNAHSIHQRSRKRLSQ 321
            W   KD +      M      +++S    + K   PPR+ S I++   + +R R+R   
Sbjct: 487 DWKGSKDVLRKASSDMSASAGYEEISDPDMEEKPSLPPRKESIIKSEGELLERERERQRT 546

Query: 322 DAYRRNSVRFLQQRRRQARPG---PQSPGSPLEEERQTQRSKPQP 363
           +  R  + +          PG   P  P   +   R ++R +P+P
Sbjct: 547 EQLRGPTPK---------PPGVILPMMPAKHIPPARDSRRPEPKP 582



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 32/125 (25%), Positives = 52/125 (41%), Gaps = 14/125 (11%)

Query: 222 PEPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQ 281
           P P    E Y  I  +     D +S   G  VEVI K L GWW I+ +D  G+ P+ ++ 
Sbjct: 364 PIPPQVEEEYYTIAEFQTTIPDGISFQAGLKVEVIEKNLSGWWYIQIEDKEGWAPATFID 423

Query: 282 KSGQDVSQAQRQIKRGAPPRRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARP 341
           K  +  + ++       P            H+ ++ RL + A   N+     +    +RP
Sbjct: 424 KYKKTSNASRPNFLAPLP------------HEVTQLRLGEAAALENNTG--SEATGPSRP 469

Query: 342 GPQSP 346
            P +P
Sbjct: 470 LPDAP 474



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 22/54 (40%), Positives = 33/54 (61%), Gaps = 5/54 (9%)

Query: 161 YRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQM----KAKRGWIPASFL 210
           Y A+A++E    +  +   G V EV EK+ SGWWFCQ+     +  GWIP+++L
Sbjct: 855 YVAVADFEGDKDTS-SFQEGTVFEVREKNSSGWWFCQVLSGAPSWEGWIPSNYL 907


>gi|41281828 NADPH oxidase organizer 1 isoform c [Homo sapiens]
          Length = 376

 Score =  106 bits (265), Expect = 3e-23
 Identities = 92/376 (24%), Positives = 152/376 (40%), Gaps = 62/376 (16%)

Query: 26  YMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPIEAGAINPENRIIPHLPAPKWFDGQ- 84
           + F V+W D S+  V R + E  +  KTLKE FP+EAG +   +R++P L      D   
Sbjct: 24  FAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEAGLLRRSDRVLPKLLGQASLDAPL 83

Query: 85  --RAAENRQG-----TLTEYCGTLMSLPTKISRCPHLLDFFKVRPDDLK--LPTDNQTKK 135
             R     +G      L  Y   L++   +++R P +  FF  +P DL+  LP  ++   
Sbjct: 84  LGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTITGFFAPQPLDLEPALPPGSRVIL 143

Query: 136 PETYLMPKDGKSTATDITGPIILQTYRAIANY--EKTSGSEMALSTGDVVEVVEKSESGW 193
           P     P    +    I   +  Q+ R +  +  + T          + ++V+ +  SGW
Sbjct: 144 PTPEEQPLSRAAGRLSIHS-LEAQSLRCLQPFCTQDTRDRPFQAQAQESLDVLLRHPSGW 202

Query: 194 WFCQMKAKR-GWIPASFLEPLDSPDETEDPEPNY--AGEPYVAIKAYTAVEGDEVSLLEG 250
           W  + + ++  W PA +LE   +P +  +  P+   +G  + A +AY +   DE+S+  G
Sbjct: 203 WLVENEDRQTAWFPAPYLEEA-APGQGREGGPSLGSSGPQFCASRAYESSRADELSVPAG 261

Query: 251 EAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHS 310
             V V+     GWW+ R  D  G  P++ L+  G     +    + G  P          
Sbjct: 262 ARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALLSGTGFRGGDDP---------- 311

Query: 311 IHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSKPQPAVPPRPS 370
                                      +AR  P+           +Q + P P VP RPS
Sbjct: 312 -------------------------AGEARGFPE----------PSQATAPPPTVPTRPS 336

Query: 371 ADLILNRCSESTKRKL 386
              I +RC   T+R L
Sbjct: 337 PGAIQSRCCTVTRRAL 352


>gi|41281811 NADPH oxidase organizer 1 isoform b [Homo sapiens]
          Length = 371

 Score =  106 bits (265), Expect = 3e-23
 Identities = 93/371 (25%), Positives = 153/371 (41%), Gaps = 57/371 (15%)

Query: 26  YMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPIEAGAINPENRIIPH-LPAPKWFDGQ 84
           + F V+W D S+  V R + E  +  KTLKE FP+EAG +   +R++P  L AP      
Sbjct: 24  FAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEAGLLRRSDRVLPKLLDAPLLGRVG 83

Query: 85  RAAEN--RQGTLTEYCGTLMSLPTKISRCPHLLDFFKVRPDDLK--LPTDNQTKKPETYL 140
           R +    R   L  Y   L++   +++R P +  FF  +P DL+  LP  ++   P    
Sbjct: 84  RTSRGLARLQLLETYSRRLLATAERVARSPTITGFFAPQPLDLEPALPPGSRVILPTPEE 143

Query: 141 MPKDGKSTATDITGPIILQTYRAIANY--EKTSGSEMALSTGDVVEVVEKSESGWWFCQM 198
            P    +    I   +  Q+ R +  +  + T          + ++V+ +  SGWW  + 
Sbjct: 144 QPLSRAAGRLSIHS-LEAQSLRCLQPFCTQDTRDRPFQAQAQESLDVLLRHPSGWWLVEN 202

Query: 199 KAKR-GWIPASFLEPLDSPDETEDPEPNY--AGEPYVAIKAYTAVEGDEVSLLEGEAVEV 255
           + ++  W PA +LE   +P +  +  P+   +G  + A +AY +   DE+S+  G  V V
Sbjct: 203 EDRQTAWFPAPYLEEA-APGQGREGGPSLGSSGPQFCASRAYESSRADELSVPAGARVRV 261

Query: 256 IHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHSIHQRS 315
           +     GWW+ R  D  G  P++ L+  G     +    + G  P               
Sbjct: 262 LETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALLSGTGFRGGDDP--------------- 306

Query: 316 RKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSKPQPAVPPRPSADLIL 375
                                 +AR  P+           +Q + P P VP RPS   I 
Sbjct: 307 --------------------AGEARGFPE----------PSQATAPPPTVPTRPSPGAIQ 336

Query: 376 NRCSESTKRKL 386
           +RC   T+R L
Sbjct: 337 SRCCTVTRRAL 347


>gi|21389405 NADPH oxidase organizer 1 isoform a [Homo sapiens]
          Length = 370

 Score =  102 bits (254), Expect = 6e-22
 Identities = 93/371 (25%), Positives = 153/371 (41%), Gaps = 58/371 (15%)

Query: 26  YMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPIEAGAINPENRIIPHL-PAPKWFDGQ 84
           + F V+W D S+  V R + E  +  KTLKE FP+EAG +   +R++P L  AP      
Sbjct: 24  FAFSVRWSDGSDTFVRRSWDEFRQL-KTLKETFPVEAGLLRRSDRVLPKLLDAPLLGRVG 82

Query: 85  RAAEN--RQGTLTEYCGTLMSLPTKISRCPHLLDFFKVRPDDLK--LPTDNQTKKPETYL 140
           R +    R   L  Y   L++   +++R P +  FF  +P DL+  LP  ++   P    
Sbjct: 83  RTSRGLARLQLLETYSRRLLATAERVARSPTITGFFAPQPLDLEPALPPGSRVILPTPEE 142

Query: 141 MPKDGKSTATDITGPIILQTYRAIANY--EKTSGSEMALSTGDVVEVVEKSESGWWFCQM 198
            P    +    I   +  Q+ R +  +  + T          + ++V+ +  SGWW  + 
Sbjct: 143 QPLSRAAGRLSIHS-LEAQSLRCLQPFCTQDTRDRPFQAQAQESLDVLLRHPSGWWLVEN 201

Query: 199 KAKR-GWIPASFLEPLDSPDETEDPEPNY--AGEPYVAIKAYTAVEGDEVSLLEGEAVEV 255
           + ++  W PA +LE   +P +  +  P+   +G  + A +AY +   DE+S+  G  V V
Sbjct: 202 EDRQTAWFPAPYLEEA-APGQGREGGPSLGSSGPQFCASRAYESSRADELSVPAGARVRV 260

Query: 256 IHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHSIHQRS 315
           +     GWW+ R  D  G  P++ L+  G     +    + G  P               
Sbjct: 261 LETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALLSGTGFRGGDDP--------------- 305

Query: 316 RKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSKPQPAVPPRPSADLIL 375
                                 +AR  P+           +Q + P P VP RPS   I 
Sbjct: 306 --------------------AGEARGFPE----------PSQATAPPPTVPTRPSPGAIQ 335

Query: 376 NRCSESTKRKL 386
           +RC   T+R L
Sbjct: 336 SRCCTVTRRAL 346


>gi|239752628 PREDICTED: hypothetical protein XP_002347816 [Homo
           sapiens]
          Length = 164

 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 43/44 (97%), Positives = 43/44 (97%)

Query: 149 ATDITGPIILQTYRAIANYEKTSGSEMALSTGDVVEVVEKSESG 192
           A DITGPIILQTYRAIANYEKTSGSEMALSTGDVVEVVEKSESG
Sbjct: 35  APDITGPIILQTYRAIANYEKTSGSEMALSTGDVVEVVEKSESG 78



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 28/104 (26%), Positives = 39/104 (37%), Gaps = 12/104 (11%)

Query: 205 IPASFLEPLDSPDETEDPE----PNYAG----EPYVAIKAYTAVEGDEVSLLEGEAVEVI 256
           +PA  LE    P     P     P+  G    + Y AI  Y    G E++L  G+ VEV+
Sbjct: 13  MPAPVLEAQMGPAMPTHPALPLAPDITGPIILQTYRAIANYEKTSGSEMALSTGDVVEVV 72

Query: 257 HKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPP 300
            K   G    +   +TG  P +      Q   Q    +  G  P
Sbjct: 73  EKSESG----QTSHLTGLLPLVLRNPQPQAPCQGSGSLAPGRTP 112


>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
          Length = 1670

 Score = 73.2 bits (178), Expect = 4e-13
 Identities = 48/169 (28%), Positives = 84/169 (49%), Gaps = 20/169 (11%)

Query: 162  RAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPD-ETE 220
            +A+ ++     + +  S  D++ V+E+ E+ WWF ++   RGW P S+++ +   + + E
Sbjct: 877  QALCSWTAKKDNHLNFSKHDIITVLEQQEN-WWFGEVHGGRGWFPKSYVKIIPGSEVKRE 935

Query: 221  DPEPNYA-------------GEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDG-WWVI 266
            +PE  YA             GE Y+A+  Y++VE  +++  EGE + V  K  DG WW  
Sbjct: 936  EPEALYAAVNKKPTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILVTQK--DGEWWTG 993

Query: 267  RKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHSIHQRS 315
               D +G FPS Y++   Q+   +    K GA  ++  I    S +  S
Sbjct: 994  SIGDRSGIFPSNYVKPKDQESFGSAS--KSGASNKKPEIAQVTSAYVAS 1040



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 45/157 (28%), Positives = 79/157 (50%), Gaps = 15/157 (9%)

Query: 136  PETYLMPKDGKS------TATDITGPIILQTYRAIANYEKTSGSEMALSTGDVVEVVEKS 189
            P  Y+ PKD +S      +      P I Q   A   Y  +   +++L+ G ++ +++K+
Sbjct: 1003 PSNYVKPKDQESFGSASKSGASNKKPEIAQVTSA---YVASGSEQLSLAPGQLILILKKN 1059

Query: 190  ESGWWFCQMKAK-----RGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAVEGDE 244
             SGWW  +++A+     +GW PAS ++ L    E   P  +   +  +A+  Y A   DE
Sbjct: 1060 TSGWWQGELQARGKKRQKGWFPASHVKLLGPSSERATPAFHPVCQ-VIAMYDYAANNEDE 1118

Query: 245  VSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQ 281
            +S  +G+ + V++K    WW    + VTG FPS Y++
Sbjct: 1119 LSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYVK 1155



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 32/130 (24%), Positives = 64/130 (49%), Gaps = 9/130 (6%)

Query: 119 KVRPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALS 178
           K++ ++ K   + Q K  +T    +  + TA+      +L  YRA+  +E  +  EM+ +
Sbjct: 700 KIQEEERKAE-EKQRKDKDTLKAEEKKRETAS------VLVNYRALYPFEARNHDEMSFN 752

Query: 179 TGDVVEVVEKS--ESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKA 236
           +GD+++V EK+  E GW +   +   GW P +++E + S +  +   P  A  P     +
Sbjct: 753 SGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKMPSSENEKAVSPKKALLPPTVSLS 812

Query: 237 YTAVEGDEVS 246
            T+   + +S
Sbjct: 813 ATSTSSEPLS 822


>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
          Length = 1697

 Score = 73.2 bits (178), Expect = 4e-13
 Identities = 48/169 (28%), Positives = 84/169 (49%), Gaps = 20/169 (11%)

Query: 162  RAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPD-ETE 220
            +A+ ++     + +  S  D++ V+E+ E+ WWF ++   RGW P S+++ +   + + E
Sbjct: 904  QALCSWTAKKDNHLNFSKHDIITVLEQQEN-WWFGEVHGGRGWFPKSYVKIIPGSEVKRE 962

Query: 221  DPEPNYA-------------GEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDG-WWVI 266
            +PE  YA             GE Y+A+  Y++VE  +++  EGE + V  K  DG WW  
Sbjct: 963  EPEALYAAVNKKPTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILVTQK--DGEWWTG 1020

Query: 267  RKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHSIHQRS 315
               D +G FPS Y++   Q+   +    K GA  ++  I    S +  S
Sbjct: 1021 SIGDRSGIFPSNYVKPKDQESFGSAS--KSGASNKKPEIAQVTSAYVAS 1067



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 45/157 (28%), Positives = 79/157 (50%), Gaps = 15/157 (9%)

Query: 136  PETYLMPKDGKS------TATDITGPIILQTYRAIANYEKTSGSEMALSTGDVVEVVEKS 189
            P  Y+ PKD +S      +      P I Q   A   Y  +   +++L+ G ++ +++K+
Sbjct: 1030 PSNYVKPKDQESFGSASKSGASNKKPEIAQVTSA---YVASGSEQLSLAPGQLILILKKN 1086

Query: 190  ESGWWFCQMKAK-----RGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAVEGDE 244
             SGWW  +++A+     +GW PAS ++ L    E   P  +   +  +A+  Y A   DE
Sbjct: 1087 TSGWWQGELQARGKKRQKGWFPASHVKLLGPSSERATPAFHPVCQ-VIAMYDYAANNEDE 1145

Query: 245  VSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQ 281
            +S  +G+ + V++K    WW    + VTG FPS Y++
Sbjct: 1146 LSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYVK 1182



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 32/130 (24%), Positives = 64/130 (49%), Gaps = 9/130 (6%)

Query: 119 KVRPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALS 178
           K++ ++ K   + Q K  +T    +  + TA+      +L  YRA+  +E  +  EM+ +
Sbjct: 727 KIQEEERKAE-EKQRKDKDTLKAEEKKRETAS------VLVNYRALYPFEARNHDEMSFN 779

Query: 179 TGDVVEVVEKS--ESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKA 236
           +GD+++V EK+  E GW +   +   GW P +++E + S +  +   P  A  P     +
Sbjct: 780 SGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKMPSSENEKAVSPKKALLPPTVSLS 839

Query: 237 YTAVEGDEVS 246
            T+   + +S
Sbjct: 840 ATSTSSEPLS 849


>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
          Length = 1249

 Score = 73.2 bits (178), Expect = 4e-13
 Identities = 48/169 (28%), Positives = 84/169 (49%), Gaps = 20/169 (11%)

Query: 162  RAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPD-ETE 220
            +A+ ++     + +  S  D++ V+E+ E+ WWF ++   RGW P S+++ +   + + E
Sbjct: 904  QALCSWTAKKDNHLNFSKHDIITVLEQQEN-WWFGEVHGGRGWFPKSYVKIIPGSEVKRE 962

Query: 221  DPEPNYA-------------GEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDG-WWVI 266
            +PE  YA             GE Y+A+  Y++VE  +++  EGE + V  K  DG WW  
Sbjct: 963  EPEALYAAVNKKPTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILVTQK--DGEWWTG 1020

Query: 267  RKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHSIHQRS 315
               D +G FPS Y++   Q+   +    K GA  ++  I    S +  S
Sbjct: 1021 SIGDRSGIFPSNYVKPKDQESFGSAS--KSGASNKKPEIAQVTSAYVAS 1067



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 45/157 (28%), Positives = 79/157 (50%), Gaps = 15/157 (9%)

Query: 136  PETYLMPKDGKS------TATDITGPIILQTYRAIANYEKTSGSEMALSTGDVVEVVEKS 189
            P  Y+ PKD +S      +      P I Q   A   Y  +   +++L+ G ++ +++K+
Sbjct: 1030 PSNYVKPKDQESFGSASKSGASNKKPEIAQVTSA---YVASGSEQLSLAPGQLILILKKN 1086

Query: 190  ESGWWFCQMKAK-----RGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAVEGDE 244
             SGWW  +++A+     +GW PAS ++ L    E   P  +   +  +A+  Y A   DE
Sbjct: 1087 TSGWWQGELQARGKKRQKGWFPASHVKLLGPSSERATPAFHPVCQ-VIAMYDYAANNEDE 1145

Query: 245  VSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQ 281
            +S  +G+ + V++K    WW    + VTG FPS Y++
Sbjct: 1146 LSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYVK 1182



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 32/130 (24%), Positives = 64/130 (49%), Gaps = 9/130 (6%)

Query: 119 KVRPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALS 178
           K++ ++ K   + Q K  +T    +  + TA+      +L  YRA+  +E  +  EM+ +
Sbjct: 727 KIQEEERKAE-EKQRKDKDTLKAEEKKRETAS------VLVNYRALYPFEARNHDEMSFN 779

Query: 179 TGDVVEVVEKS--ESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKA 236
           +GD+++V EK+  E GW +   +   GW P +++E + S +  +   P  A  P     +
Sbjct: 780 SGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKMPSSENEKAVSPKKALLPPTVSLS 839

Query: 237 YTAVEGDEVS 246
            T+   + +S
Sbjct: 840 ATSTSSEPLS 849


>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
          Length = 1220

 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 41/160 (25%), Positives = 77/160 (48%), Gaps = 14/160 (8%)

Query: 136  PETYLMPKDGKSTAT-DITGPIIL--QTYRAIANYEKTSGSEMALSTGDVVEVVEKSESG 192
            P  Y+  KD + + T   TG +    +  + IA+Y  T   ++ L+ G ++ + +K+  G
Sbjct: 1051 PSNYVRLKDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGG 1110

Query: 193  WWFCQMKAKR-----GWIPASFLEPLD------SPDETEDPEPNYAGEPYVAIKAYTAVE 241
            WW  +++A+      GW PA++++ L       +P E        A    + +  YTA  
Sbjct: 1111 WWEGELQARGKKRQIGWFPANYVKLLSPGTSKITPTEPPKSTALAAVCQVIGMYDYTAQN 1170

Query: 242  GDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQ 281
             DE++  +G+ + V++K    WW    +   G FPS Y++
Sbjct: 1171 DDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVK 1210



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 34/141 (24%), Positives = 68/141 (48%), Gaps = 24/141 (17%)

Query: 162  RAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSP----- 216
            +A+  +     + +  +  DV+ V+E+ +  WWF +++ ++GW P S+++ +  P     
Sbjct: 919  QALYPWRAKKDNHLNFNKNDVITVLEQQDM-WWFGEVQGQKGWFPKSYVKLISGPIRKST 977

Query: 217  ----DETEDP-----------EPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLD 261
                  +E P           +P  +GE ++A+  Y + E  +++  +G+ + V  K  D
Sbjct: 978  SMDSGSSESPASLKRVASPAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVILVTKK--D 1035

Query: 262  G-WWVIRKDDVTGYFPSMYLQ 281
            G WW     D  G FPS Y++
Sbjct: 1036 GDWWTGTVGDKAGVFPSNYVR 1056



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 41/173 (23%), Positives = 79/173 (45%), Gaps = 14/173 (8%)

Query: 142  PKDGKSTATDITGPIIL-QTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKA 200
            P   K  A+    P++  + + A+  YE +   ++    GDV+ +V K +  WW   +  
Sbjct: 987  PASLKRVASPAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVI-LVTKKDGDWWTGTVGD 1045

Query: 201  KRGWIPASFLEPLDSPDE-TEDPEPNYAGEPYVA--IKAYTAVEGDEVSLLEGEAVEVIH 257
            K G  P++++   DS    T     +   +P +A  I +YTA   ++++L  G+ + +  
Sbjct: 1046 KAGVFPSNYVRLKDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRK 1105

Query: 258  KLLDGWW-----VIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPPRRSSI 305
            K   GWW        K    G+FP+ Y++     +S    +I    PP+ +++
Sbjct: 1106 KNPGGWWEGELQARGKKRQIGWFPANYVKL----LSPGTSKITPTEPPKSTAL 1154



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 26/71 (36%), Positives = 38/71 (53%), Gaps = 10/71 (14%)

Query: 161 YRAIANYEKTSGSEMALSTGDVVEV----VEKS---ESGWWFCQMKAKRGWIPASFLEPL 213
           YRA+  +E  S  E+ +  GD+V V    V++S   E GW   ++K K GW PA++ E +
Sbjct: 745 YRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804

Query: 214 DSPDETEDPEP 224
               E E P P
Sbjct: 805 ---PENEVPAP 812



 Score = 33.1 bits (74), Expect = 0.44
 Identities = 11/55 (20%), Positives = 29/55 (52%)

Query: 166  NYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETE 220
            +Y   +  E+A + G ++ V+ K +  WW  ++  + G  P+++++     D ++
Sbjct: 1165 DYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVKLTTDMDPSQ 1219


>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
          Length = 1721

 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 41/160 (25%), Positives = 77/160 (48%), Gaps = 14/160 (8%)

Query: 136  PETYLMPKDGKSTAT-DITGPIIL--QTYRAIANYEKTSGSEMALSTGDVVEVVEKSESG 192
            P  Y+  KD + + T   TG +    +  + IA+Y  T   ++ L+ G ++ + +K+  G
Sbjct: 1051 PSNYVRLKDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGG 1110

Query: 193  WWFCQMKAKR-----GWIPASFLEPLD------SPDETEDPEPNYAGEPYVAIKAYTAVE 241
            WW  +++A+      GW PA++++ L       +P E        A    + +  YTA  
Sbjct: 1111 WWEGELQARGKKRQIGWFPANYVKLLSPGTSKITPTEPPKSTALAAVCQVIGMYDYTAQN 1170

Query: 242  GDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQ 281
             DE++  +G+ + V++K    WW    +   G FPS Y++
Sbjct: 1171 DDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVK 1210



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 34/141 (24%), Positives = 68/141 (48%), Gaps = 24/141 (17%)

Query: 162  RAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSP----- 216
            +A+  +     + +  +  DV+ V+E+ +  WWF +++ ++GW P S+++ +  P     
Sbjct: 919  QALYPWRAKKDNHLNFNKNDVITVLEQQDM-WWFGEVQGQKGWFPKSYVKLISGPIRKST 977

Query: 217  ----DETEDP-----------EPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLD 261
                  +E P           +P  +GE ++A+  Y + E  +++  +G+ + V  K  D
Sbjct: 978  SMDSGSSESPASLKRVASPAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVILVTKK--D 1035

Query: 262  G-WWVIRKDDVTGYFPSMYLQ 281
            G WW     D  G FPS Y++
Sbjct: 1036 GDWWTGTVGDKAGVFPSNYVR 1056



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 41/173 (23%), Positives = 79/173 (45%), Gaps = 14/173 (8%)

Query: 142  PKDGKSTATDITGPIIL-QTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKA 200
            P   K  A+    P++  + + A+  YE +   ++    GDV+ +V K +  WW   +  
Sbjct: 987  PASLKRVASPAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVI-LVTKKDGDWWTGTVGD 1045

Query: 201  KRGWIPASFLEPLDSPDE-TEDPEPNYAGEPYVA--IKAYTAVEGDEVSLLEGEAVEVIH 257
            K G  P++++   DS    T     +   +P +A  I +YTA   ++++L  G+ + +  
Sbjct: 1046 KAGVFPSNYVRLKDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRK 1105

Query: 258  KLLDGWW-----VIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPPRRSSI 305
            K   GWW        K    G+FP+ Y++     +S    +I    PP+ +++
Sbjct: 1106 KNPGGWWEGELQARGKKRQIGWFPANYVKL----LSPGTSKITPTEPPKSTAL 1154



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 26/71 (36%), Positives = 38/71 (53%), Gaps = 10/71 (14%)

Query: 161 YRAIANYEKTSGSEMALSTGDVVEV----VEKS---ESGWWFCQMKAKRGWIPASFLEPL 213
           YRA+  +E  S  E+ +  GD+V V    V++S   E GW   ++K K GW PA++ E +
Sbjct: 745 YRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804

Query: 214 DSPDETEDPEP 224
               E E P P
Sbjct: 805 ---PENEVPAP 812



 Score = 33.1 bits (74), Expect = 0.44
 Identities = 11/55 (20%), Positives = 29/55 (52%)

Query: 166  NYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETE 220
            +Y   +  E+A + G ++ V+ K +  WW  ++  + G  P+++++     D ++
Sbjct: 1165 DYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVKLTTDMDPSQ 1219


>gi|47519798 neutrophil cytosolic factor 4 isoform 1 [Homo sapiens]
          Length = 339

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 56/212 (26%), Positives = 98/212 (46%), Gaps = 10/212 (4%)

Query: 15  EKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPIEAGAINPENRIIPH 74
           EKR   S H+V++  VK +  S+ ++YRR+ + +     L+E F  ++ + +     +P 
Sbjct: 31  EKRGFTS-HFVFVIEVKTKGGSKYLIYRRYRQFHALQSKLEERFGPDSKS-SALACTLPT 88

Query: 75  LPAPKWFD-GQRAAENRQGTLTEYCGTLMSLPTKISRCPHLLDFFKVRP-DDLKLPTDNQ 132
           LPA  +    Q  AE R   L  Y  +L+SLP  +     +  FF   P D  ++P   +
Sbjct: 89  LPAKVYVGVKQEIAEMRIPALNAYMKSLLSLPVWVLMDEDVRIFFYQSPYDSEQVPQALR 148

Query: 133 TKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALS--TGDVVEVVEKSE 190
             +P T    +  KS +        +   RA A ++ T  S++ L+   GDV+ ++ +  
Sbjct: 149 RLRPRT----RKVKSVSPQGNSVDRMAAPRAEALFDFTGNSKLELNFKAGDVIFLLSRIN 204

Query: 191 SGWWFCQMKAKRGWIPASFLEPLDSPDETEDP 222
             W    ++   G  P SF++ L    E +DP
Sbjct: 205 KDWLEGTVRGATGIFPLSFVKILKDFPEEDDP 236


>gi|163644267 neutrophil cytosolic factor 4 isoform 2 [Homo sapiens]
          Length = 348

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 56/212 (26%), Positives = 98/212 (46%), Gaps = 10/212 (4%)

Query: 15  EKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPIEAGAINPENRIIPH 74
           EKR   S H+V++  VK +  S+ ++YRR+ + +     L+E F  ++ + +     +P 
Sbjct: 31  EKRGFTS-HFVFVIEVKTKGGSKYLIYRRYRQFHALQSKLEERFGPDSKS-SALACTLPT 88

Query: 75  LPAPKWFD-GQRAAENRQGTLTEYCGTLMSLPTKISRCPHLLDFFKVRP-DDLKLPTDNQ 132
           LPA  +    Q  AE R   L  Y  +L+SLP  +     +  FF   P D  ++P   +
Sbjct: 89  LPAKVYVGVKQEIAEMRIPALNAYMKSLLSLPVWVLMDEDVRIFFYQSPYDSEQVPQALR 148

Query: 133 TKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALS--TGDVVEVVEKSE 190
             +P T    +  KS +        +   RA A ++ T  S++ L+   GDV+ ++ +  
Sbjct: 149 RLRPRT----RKVKSVSPQGNSVDRMAAPRAEALFDFTGNSKLELNFKAGDVIFLLSRIN 204

Query: 191 SGWWFCQMKAKRGWIPASFLEPLDSPDETEDP 222
             W    ++   G  P SF++ L    E +DP
Sbjct: 205 KDWLEGTVRGATGIFPLSFVKILKDFPEEDDP 236


>gi|20149528 proline-serine-threonine phosphatase interacting
           protein 1 [Homo sapiens]
          Length = 416

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 23/55 (41%), Positives = 36/55 (65%)

Query: 159 QTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPL 213
           Q YRA+ +Y   +  E+ LS GD++EV+ + E GWW  +   +RG++P S+LE L
Sbjct: 362 QEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLEKL 416



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 22/59 (37%), Positives = 33/59 (55%)

Query: 224 PNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQK 282
           P    + Y A+  YTA   DE+ L  G+ +EVI +  DGWW + ++   G+ P  YL+K
Sbjct: 357 PASPAQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLEK 415


>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
           sapiens]
          Length = 756

 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 38/145 (26%), Positives = 61/145 (42%), Gaps = 30/145 (20%)

Query: 166 NYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDS-------PDE 218
           +Y      E+ L  G++VE++++ E GWW  +   + G  P++F+E LDS       PD 
Sbjct: 93  SYSPEQADELKLQAGEIVEMIKEIEDGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNPDM 152

Query: 219 TE----------------DPEPNYA-----GEPYVAIKAYTAVEGDEVSLLEGEAVEVIH 257
                             D  P+Y       E Y  +  Y     DE++L  G+ V+V+ 
Sbjct: 153 PSVSPGPQRPPKLSSLAYDSPPDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLS 212

Query: 258 KLLD--GWWVIRKDDVTGYFPSMYL 280
           K  +  GWW        G FP  ++
Sbjct: 213 KTTEDKGWWEGECQGRRGVFPDNFV 237



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 38/133 (28%), Positives = 59/133 (44%), Gaps = 15/133 (11%)

Query: 164 IANYEKTSGSEMALSTGDVVEVVEKSES-GWWFCQMKAKRGWIPASFL----EPLDSPDE 218
           +A Y      E++L+ GDVV  V    + GW   +   + G  P   +    E L    E
Sbjct: 6   LAGYRAQKEDELSLAPGDVVRQVRWVPARGWLRGEFGGRYGLFPERLVQEIPETLRGSGE 65

Query: 219 TEDPE-------PNYAGEPYVAIK---AYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRK 268
              P        P     P    K   +Y+  + DE+ L  GE VE+I ++ DGWW+ +K
Sbjct: 66  ARRPRCARRRGHPAKHPRPQRWCKVNFSYSPEQADELKLQAGEIVEMIKEIEDGWWLGKK 125

Query: 269 DDVTGYFPSMYLQ 281
           +   G FPS +++
Sbjct: 126 NGQLGAFPSNFVE 138



 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 46/211 (21%), Positives = 84/211 (39%), Gaps = 24/211 (11%)

Query: 159 QTYRAIANYEKTSGSEMALSTGDVVEVVEKS--ESGWWFCQMKAKRGWIPASFLEPLDSP 216
           + YR + +Y+  +  E+AL  GDVV+V+ K+  + GWW  + + +RG  P +F+ P    
Sbjct: 184 EVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFVLP---- 239

Query: 217 DETEDPEPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFP 276
                P P     P   +   +A   +   L+   ++  + KL            TG   
Sbjct: 240 -----PPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATA--------TTGPSK 286

Query: 277 SMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQRR 336
           +   +   +D   +Q+   R + P     ++  S H   RKR      ++ SV   ++  
Sbjct: 287 AKTSRTPSRD---SQKLTSRDSGP-NGGFQSGGSYHP-GRKRSKTQTPQQRSVSSQEEEH 341

Query: 337 RQARPGPQSPGSPLEEERQTQRSKPQPAVPP 367
                 P    +P+ ++  T    P P   P
Sbjct: 342 SSPVKAPSVKRTPMPDKTATPERPPAPENAP 372


>gi|89886447 nitric oxide synthase trafficker isoform 2 [Homo
           sapiens]
          Length = 506

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 28/103 (27%), Positives = 47/103 (45%)

Query: 113 HLLDFFKVRPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSG 172
           H   + K+    L    +N   K  +      G ST       +  +  +A+ +++    
Sbjct: 395 HTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQD 454

Query: 173 SEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDS 215
            E+ L  GD+V + EK E GWWF  +  K+G  PA+++E L S
Sbjct: 455 DELNLEKGDIVIIHEKKEEGWWFGSLNGKKGHFPAAYVEELPS 497



 Score = 36.6 bits (83), Expect = 0.040
 Identities = 15/50 (30%), Positives = 31/50 (62%)

Query: 233 AIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQK 282
           A+ ++ A + DE++L +G+ V +  K  +GWW    +   G+FP+ Y+++
Sbjct: 445 ALYSFQARQDDELNLEKGDIVIIHEKKEEGWWFGSLNGKKGHFPAAYVEE 494


>gi|16418431 nitric oxide synthase trafficker isoform 1 [Homo
           sapiens]
          Length = 428

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 28/103 (27%), Positives = 47/103 (45%)

Query: 113 HLLDFFKVRPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSG 172
           H   + K+    L    +N   K  +      G ST       +  +  +A+ +++    
Sbjct: 317 HTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQD 376

Query: 173 SEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDS 215
            E+ L  GD+V + EK E GWWF  +  K+G  PA+++E L S
Sbjct: 377 DELNLEKGDIVIIHEKKEEGWWFGSLNGKKGHFPAAYVEELPS 419



 Score = 36.6 bits (83), Expect = 0.040
 Identities = 15/50 (30%), Positives = 31/50 (62%)

Query: 233 AIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQK 282
           A+ ++ A + DE++L +G+ V +  K  +GWW    +   G+FP+ Y+++
Sbjct: 367 ALYSFQARQDDELNLEKGDIVIIHEKKEEGWWFGSLNGKKGHFPAAYVEE 416


>gi|11321634 CD2-associated protein [Homo sapiens]
          Length = 639

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 54/183 (29%), Positives = 80/183 (43%), Gaps = 26/183 (14%)

Query: 92  GTLTEYCGTLMSLPTKISRCPHLLDFFKVRPDDLKLPT---DNQTKKPETYLM-----PK 143
           G ++E     ++ P KI R     D FK     L+  T   + + KKPE  L+     PK
Sbjct: 195 GNVSETASGSVTQPKKI-RGIGFGDIFKEGSVKLRTRTSSSETEEKKPEKPLILQSLGPK 253

Query: 144 DG--KSTATDITGPIILQTY-RAIANYEKTSGSEMALSTGDVVEVVEKS--ESGWWFCQM 198
               + T TD  G I  + Y R +  YE T+  E+    G+++ ++ K   E+GWW  ++
Sbjct: 254 TQSVEITKTDTEGKIKAKEYCRTLFAYEGTNEDELTFKEGEIIHLISKETGEAGWWRGEL 313

Query: 199 KAKRGWIPASFLEPL-----DSPDETEDPEPNYAGEP----YVAIKAYTAV---EGDEVS 246
             K G  P +F   +     D P   + P P  A  P      A K Y ++   E DE S
Sbjct: 314 NGKEGVFPDNFAVQINELDKDFPKPKKPPPPAKAPAPKPELIAAEKKYFSLKPEEKDEKS 373

Query: 247 LLE 249
            LE
Sbjct: 374 TLE 376



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 20/72 (27%), Positives = 37/72 (51%)

Query: 162 RAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETED 221
           + +  Y   +  E+ L  GD++++ E+ E GWW   +  K G  P++F++ L+  D+ E 
Sbjct: 114 KVLFEYIPQNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVKELEVTDDGET 173

Query: 222 PEPNYAGEPYVA 233
            E     E  +A
Sbjct: 174 HEAQDDSETVLA 185



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 29/156 (18%), Positives = 61/156 (39%), Gaps = 39/156 (25%)

Query: 166 NYEKTSGSEMALSTGDVVEVVEK-SESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPE- 223
           +Y+     E+ +  G+++  V+K  E GW   ++  +RG  P +F++ +    E +D   
Sbjct: 9   DYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEIKRETEFKDDSL 68

Query: 224 ----------------------PNYAGEPYVAIK---------------AYTAVEGDEVS 246
                                 P    +P+   K                Y     DE+ 
Sbjct: 69  PIKRERHGNVASLVQRISTYGLPAGGIQPHPQTKNIKKKTKKRQCKVLFEYIPQNEDELE 128

Query: 247 LLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQK 282
           L  G+ +++  ++ +GWW    ++  G FPS ++++
Sbjct: 129 LKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVKE 164



 Score = 33.9 bits (76), Expect = 0.26
 Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 13/145 (8%)

Query: 236 AYTAVEGDEVSLLEGEAVEVIHKLLD--GWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQ 293
           AY     DE++  EGE + +I K     GWW    +   G FP  +  +   ++ +   +
Sbjct: 279 AYEGTNEDELTFKEGEIIHLISKETGEAGWWRGELNGKEGVFPDNFAVQI-NELDKDFPK 337

Query: 294 IKRGAPPRRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQR-RRQARP--GPQSPGSPL 350
            K+  PP ++       I    +K  S     ++    L+Q+  + A P   P+ P  P 
Sbjct: 338 PKKPPPPAKAPAPKPELI-AAEKKYFSLKPEEKDEKSTLEQKPSKPAAPQVPPKKPTPPT 396

Query: 351 EEERQTQRS------KPQPAVPPRP 369
           +     + S      +P+  VPP P
Sbjct: 397 KASNLLRSSGTVYPKRPEKPVPPPP 421


>gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo
           sapiens]
          Length = 492

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 40/164 (24%), Positives = 75/164 (45%), Gaps = 8/164 (4%)

Query: 162 RAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETE- 220
           +A+ +++  +  E++   GD V ++ K +  W+  +   + G  P S++E L  P++ + 
Sbjct: 261 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPPEKAQP 320

Query: 221 --DPEPNYAGEPYVAIKAY--TAVEGDEVSLLEGEAVEVIHKLLDGWW--VIRKDDVTGY 274
              P P   GE   AI  Y   A    E+SL +G+ V ++ ++   W+   I   +  G 
Sbjct: 321 ARPPPPAQPGEIGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGI 380

Query: 275 FPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHSIHQRSRKR 318
           FP  Y++   ++   A+       P   SS R  HS+     +R
Sbjct: 381 FPVSYVEVVKKNTKGAEDYPDPPIPHSYSSDR-IHSLSSNKPQR 423



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 35/152 (23%), Positives = 67/152 (44%), Gaps = 35/152 (23%)

Query: 166 NYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKA--KRGWIPASFLEPLD-----SPDE 218
           N+   +  E++L  GD V ++++ +  W+  ++    ++G  P S++E +      + D 
Sbjct: 340 NFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVVKKNTKGAEDY 399

Query: 219 TEDPEPNY--------------------------AGEPYVAIKAYTAVEGDEVSLLEGEA 252
            + P P+                            GEP+ A+  YT    DE+ L E + 
Sbjct: 400 PDPPIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGGEPFQALYNYTPRNEDELELRESDV 459

Query: 253 VEVIHKLLDGWWV--IRKDDVTGYFPSMYLQK 282
           ++V+ K  DGW+V   R+    G FP  Y+++
Sbjct: 460 IDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKR 491



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 15/57 (26%), Positives = 32/57 (56%), Gaps = 2/57 (3%)

Query: 159 QTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKR--GWIPASFLEPL 213
           + ++A+ NY   +  E+ L   DV++V+EK + GW+    +  +  G  P ++++ L
Sbjct: 436 EPFQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 492



 Score = 30.0 bits (66), Expect = 3.7
 Identities = 14/53 (26%), Positives = 25/53 (47%)

Query: 230 PYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQK 282
           P  A+  + A    E+S  +G+ V ++ K+   W+        G FP  Y++K
Sbjct: 259 PAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEK 311


>gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo
           sapiens]
          Length = 1004

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 40/164 (24%), Positives = 75/164 (45%), Gaps = 8/164 (4%)

Query: 162 RAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETE- 220
           +A+ +++  +  E++   GD V ++ K +  W+  +   + G  P S++E L  P++ + 
Sbjct: 773 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPPEKAQP 832

Query: 221 --DPEPNYAGEPYVAIKAY--TAVEGDEVSLLEGEAVEVIHKLLDGWW--VIRKDDVTGY 274
              P P   GE   AI  Y   A    E+SL +G+ V ++ ++   W+   I   +  G 
Sbjct: 833 ARPPPPAQPGEIGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGI 892

Query: 275 FPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHSIHQRSRKR 318
           FP  Y++   ++   A+       P   SS R  HS+     +R
Sbjct: 893 FPVSYVEVVKKNTKGAEDYPDPPIPHSYSSDR-IHSLSSNKPQR 935



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 35/152 (23%), Positives = 67/152 (44%), Gaps = 35/152 (23%)

Query: 166  NYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKA--KRGWIPASFLEPLD-----SPDE 218
            N+   +  E++L  GD V ++++ +  W+  ++    ++G  P S++E +      + D 
Sbjct: 852  NFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVVKKNTKGAEDY 911

Query: 219  TEDPEPNY--------------------------AGEPYVAIKAYTAVEGDEVSLLEGEA 252
             + P P+                            GEP+ A+  YT    DE+ L E + 
Sbjct: 912  PDPPIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGGEPFQALYNYTPRNEDELELRESDV 971

Query: 253  VEVIHKLLDGWWV--IRKDDVTGYFPSMYLQK 282
            ++V+ K  DGW+V   R+    G FP  Y+++
Sbjct: 972  IDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKR 1003



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 15/57 (26%), Positives = 32/57 (56%), Gaps = 2/57 (3%)

Query: 159  QTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKR--GWIPASFLEPL 213
            + ++A+ NY   +  E+ L   DV++V+EK + GW+    +  +  G  P ++++ L
Sbjct: 948  EPFQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 1004



 Score = 30.0 bits (66), Expect = 3.7
 Identities = 14/53 (26%), Positives = 25/53 (47%)

Query: 230 PYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQK 282
           P  A+  + A    E+S  +G+ V ++ K+   W+        G FP  Y++K
Sbjct: 771 PAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEK 823


>gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo
           sapiens]
          Length = 824

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 40/164 (24%), Positives = 75/164 (45%), Gaps = 8/164 (4%)

Query: 162 RAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETE- 220
           +A+ +++  +  E++   GD V ++ K +  W+  +   + G  P S++E L  P++ + 
Sbjct: 593 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPPEKAQP 652

Query: 221 --DPEPNYAGEPYVAIKAY--TAVEGDEVSLLEGEAVEVIHKLLDGWW--VIRKDDVTGY 274
              P P   GE   AI  Y   A    E+SL +G+ V ++ ++   W+   I   +  G 
Sbjct: 653 ARPPPPAQPGEIGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGI 712

Query: 275 FPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHSIHQRSRKR 318
           FP  Y++   ++   A+       P   SS R  HS+     +R
Sbjct: 713 FPVSYVEVVKKNTKGAEDYPDPPIPHSYSSDR-IHSLSSNKPQR 755



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 35/152 (23%), Positives = 67/152 (44%), Gaps = 35/152 (23%)

Query: 166 NYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKA--KRGWIPASFLEPLD-----SPDE 218
           N+   +  E++L  GD V ++++ +  W+  ++    ++G  P S++E +      + D 
Sbjct: 672 NFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVVKKNTKGAEDY 731

Query: 219 TEDPEPNY--------------------------AGEPYVAIKAYTAVEGDEVSLLEGEA 252
            + P P+                            GEP+ A+  YT    DE+ L E + 
Sbjct: 732 PDPPIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGGEPFQALYNYTPRNEDELELRESDV 791

Query: 253 VEVIHKLLDGWWV--IRKDDVTGYFPSMYLQK 282
           ++V+ K  DGW+V   R+    G FP  Y+++
Sbjct: 792 IDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKR 823



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 15/57 (26%), Positives = 32/57 (56%), Gaps = 2/57 (3%)

Query: 159 QTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKR--GWIPASFLEPL 213
           + ++A+ NY   +  E+ L   DV++V+EK + GW+    +  +  G  P ++++ L
Sbjct: 768 EPFQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 824



 Score = 30.0 bits (66), Expect = 3.7
 Identities = 14/53 (26%), Positives = 25/53 (47%)

Query: 230 PYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQK 282
           P  A+  + A    E+S  +G+ V ++ K+   W+        G FP  Y++K
Sbjct: 591 PAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEK 643


>gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo
           sapiens]
          Length = 661

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 40/164 (24%), Positives = 75/164 (45%), Gaps = 8/164 (4%)

Query: 162 RAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETE- 220
           +A+ +++  +  E++   GD V ++ K +  W+  +   + G  P S++E L  P++ + 
Sbjct: 430 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPPEKAQP 489

Query: 221 --DPEPNYAGEPYVAIKAY--TAVEGDEVSLLEGEAVEVIHKLLDGWW--VIRKDDVTGY 274
              P P   GE   AI  Y   A    E+SL +G+ V ++ ++   W+   I   +  G 
Sbjct: 490 ARPPPPAQPGEIGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGI 549

Query: 275 FPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHSIHQRSRKR 318
           FP  Y++   ++   A+       P   SS R  HS+     +R
Sbjct: 550 FPVSYVEVVKKNTKGAEDYPDPPIPHSYSSDR-IHSLSSNKPQR 592



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 35/152 (23%), Positives = 67/152 (44%), Gaps = 35/152 (23%)

Query: 166 NYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKA--KRGWIPASFLEPLD-----SPDE 218
           N+   +  E++L  GD V ++++ +  W+  ++    ++G  P S++E +      + D 
Sbjct: 509 NFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVVKKNTKGAEDY 568

Query: 219 TEDPEPNY--------------------------AGEPYVAIKAYTAVEGDEVSLLEGEA 252
            + P P+                            GEP+ A+  YT    DE+ L E + 
Sbjct: 569 PDPPIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGGEPFQALYNYTPRNEDELELRESDV 628

Query: 253 VEVIHKLLDGWWV--IRKDDVTGYFPSMYLQK 282
           ++V+ K  DGW+V   R+    G FP  Y+++
Sbjct: 629 IDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKR 660



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 15/57 (26%), Positives = 32/57 (56%), Gaps = 2/57 (3%)

Query: 159 QTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKR--GWIPASFLEPL 213
           + ++A+ NY   +  E+ L   DV++V+EK + GW+    +  +  G  P ++++ L
Sbjct: 605 EPFQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 661



 Score = 30.0 bits (66), Expect = 3.7
 Identities = 14/53 (26%), Positives = 25/53 (47%)

Query: 230 PYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQK 282
           P  A+  + A    E+S  +G+ V ++ K+   W+        G FP  Y++K
Sbjct: 428 PAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEK 480


>gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo
           sapiens]
          Length = 731

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 40/164 (24%), Positives = 75/164 (45%), Gaps = 8/164 (4%)

Query: 162 RAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETE- 220
           +A+ +++  +  E++   GD V ++ K +  W+  +   + G  P S++E L  P++ + 
Sbjct: 500 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPPEKAQP 559

Query: 221 --DPEPNYAGEPYVAIKAY--TAVEGDEVSLLEGEAVEVIHKLLDGWW--VIRKDDVTGY 274
              P P   GE   AI  Y   A    E+SL +G+ V ++ ++   W+   I   +  G 
Sbjct: 560 ARPPPPAQPGEIGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGI 619

Query: 275 FPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHSIHQRSRKR 318
           FP  Y++   ++   A+       P   SS R  HS+     +R
Sbjct: 620 FPVSYVEVVKKNTKGAEDYPDPPIPHSYSSDR-IHSLSSNKPQR 662



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 35/152 (23%), Positives = 67/152 (44%), Gaps = 35/152 (23%)

Query: 166 NYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKA--KRGWIPASFLEPLD-----SPDE 218
           N+   +  E++L  GD V ++++ +  W+  ++    ++G  P S++E +      + D 
Sbjct: 579 NFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVVKKNTKGAEDY 638

Query: 219 TEDPEPNY--------------------------AGEPYVAIKAYTAVEGDEVSLLEGEA 252
            + P P+                            GEP+ A+  YT    DE+ L E + 
Sbjct: 639 PDPPIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGGEPFQALYNYTPRNEDELELRESDV 698

Query: 253 VEVIHKLLDGWWV--IRKDDVTGYFPSMYLQK 282
           ++V+ K  DGW+V   R+    G FP  Y+++
Sbjct: 699 IDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKR 730



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 15/57 (26%), Positives = 32/57 (56%), Gaps = 2/57 (3%)

Query: 159 QTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKR--GWIPASFLEPL 213
           + ++A+ NY   +  E+ L   DV++V+EK + GW+    +  +  G  P ++++ L
Sbjct: 675 EPFQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 731



 Score = 30.0 bits (66), Expect = 3.7
 Identities = 14/53 (26%), Positives = 25/53 (47%)

Query: 230 PYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQK 282
           P  A+  + A    E+S  +G+ V ++ K+   W+        G FP  Y++K
Sbjct: 498 PAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEK 550


>gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo
           sapiens]
          Length = 644

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 40/164 (24%), Positives = 75/164 (45%), Gaps = 8/164 (4%)

Query: 162 RAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETE- 220
           +A+ +++  +  E++   GD V ++ K +  W+  +   + G  P S++E L  P++ + 
Sbjct: 413 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPPEKAQP 472

Query: 221 --DPEPNYAGEPYVAIKAY--TAVEGDEVSLLEGEAVEVIHKLLDGWW--VIRKDDVTGY 274
              P P   GE   AI  Y   A    E+SL +G+ V ++ ++   W+   I   +  G 
Sbjct: 473 ARPPPPAQPGEIGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGI 532

Query: 275 FPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHSIHQRSRKR 318
           FP  Y++   ++   A+       P   SS R  HS+     +R
Sbjct: 533 FPVSYVEVVKKNTKGAEDYPDPPIPHSYSSDR-IHSLSSNKPQR 575



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 35/152 (23%), Positives = 67/152 (44%), Gaps = 35/152 (23%)

Query: 166 NYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKA--KRGWIPASFLEPLD-----SPDE 218
           N+   +  E++L  GD V ++++ +  W+  ++    ++G  P S++E +      + D 
Sbjct: 492 NFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVVKKNTKGAEDY 551

Query: 219 TEDPEPNY--------------------------AGEPYVAIKAYTAVEGDEVSLLEGEA 252
            + P P+                            GEP+ A+  YT    DE+ L E + 
Sbjct: 552 PDPPIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGGEPFQALYNYTPRNEDELELRESDV 611

Query: 253 VEVIHKLLDGWWV--IRKDDVTGYFPSMYLQK 282
           ++V+ K  DGW+V   R+    G FP  Y+++
Sbjct: 612 IDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKR 643



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 15/57 (26%), Positives = 32/57 (56%), Gaps = 2/57 (3%)

Query: 159 QTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKR--GWIPASFLEPL 213
           + ++A+ NY   +  E+ L   DV++V+EK + GW+    +  +  G  P ++++ L
Sbjct: 588 EPFQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 644



 Score = 30.0 bits (66), Expect = 3.7
 Identities = 14/53 (26%), Positives = 25/53 (47%)

Query: 230 PYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQK 282
           P  A+  + A    E+S  +G+ V ++ K+   W+        G FP  Y++K
Sbjct: 411 PAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEK 463


>gi|10947118 sorbin and SH3 domain containing 2 isoform 2 [Homo
            sapiens]
          Length = 1100

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 40/164 (24%), Positives = 75/164 (45%), Gaps = 8/164 (4%)

Query: 162  RAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETE- 220
            +A+ +++  +  E++   GD V ++ K +  W+  +   + G  P S++E L  P++ + 
Sbjct: 869  KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPPEKAQP 928

Query: 221  --DPEPNYAGEPYVAIKAY--TAVEGDEVSLLEGEAVEVIHKLLDGWW--VIRKDDVTGY 274
               P P   GE   AI  Y   A    E+SL +G+ V ++ ++   W+   I   +  G 
Sbjct: 929  ARPPPPAQPGEIGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGI 988

Query: 275  FPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHSIHQRSRKR 318
            FP  Y++   ++   A+       P   SS R  HS+     +R
Sbjct: 989  FPVSYVEVVKKNTKGAEDYPDPPIPHSYSSDR-IHSLSSNKPQR 1031



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 35/152 (23%), Positives = 67/152 (44%), Gaps = 35/152 (23%)

Query: 166  NYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKA--KRGWIPASFLEPLD-----SPDE 218
            N+   +  E++L  GD V ++++ +  W+  ++    ++G  P S++E +      + D 
Sbjct: 948  NFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVVKKNTKGAEDY 1007

Query: 219  TEDPEPNY--------------------------AGEPYVAIKAYTAVEGDEVSLLEGEA 252
             + P P+                            GEP+ A+  YT    DE+ L E + 
Sbjct: 1008 PDPPIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGGEPFQALYNYTPRNEDELELRESDV 1067

Query: 253  VEVIHKLLDGWWV--IRKDDVTGYFPSMYLQK 282
            ++V+ K  DGW+V   R+    G FP  Y+++
Sbjct: 1068 IDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKR 1099



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 15/57 (26%), Positives = 32/57 (56%), Gaps = 2/57 (3%)

Query: 159  QTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKR--GWIPASFLEPL 213
            + ++A+ NY   +  E+ L   DV++V+EK + GW+    +  +  G  P ++++ L
Sbjct: 1044 EPFQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 1100



 Score = 30.0 bits (66), Expect = 3.7
 Identities = 14/53 (26%), Positives = 25/53 (47%)

Query: 230 PYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQK 282
           P  A+  + A    E+S  +G+ V ++ K+   W+        G FP  Y++K
Sbjct: 867 PAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEK 919


>gi|194733749 sorbin and SH3 domain containing 2 isoform 1 [Homo
           sapiens]
          Length = 666

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 40/164 (24%), Positives = 75/164 (45%), Gaps = 8/164 (4%)

Query: 162 RAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETE- 220
           +A+ +++  +  E++   GD V ++ K +  W+  +   + G  P S++E L  P++ + 
Sbjct: 435 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPPEKAQP 494

Query: 221 --DPEPNYAGEPYVAIKAY--TAVEGDEVSLLEGEAVEVIHKLLDGWW--VIRKDDVTGY 274
              P P   GE   AI  Y   A    E+SL +G+ V ++ ++   W+   I   +  G 
Sbjct: 495 ARPPPPAQPGEIGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGI 554

Query: 275 FPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHSIHQRSRKR 318
           FP  Y++   ++   A+       P   SS R  HS+     +R
Sbjct: 555 FPVSYVEVVKKNTKGAEDYPDPPIPHSYSSDR-IHSLSSNKPQR 597



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 35/152 (23%), Positives = 67/152 (44%), Gaps = 35/152 (23%)

Query: 166 NYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKA--KRGWIPASFLEPLD-----SPDE 218
           N+   +  E++L  GD V ++++ +  W+  ++    ++G  P S++E +      + D 
Sbjct: 514 NFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVVKKNTKGAEDY 573

Query: 219 TEDPEPNY--------------------------AGEPYVAIKAYTAVEGDEVSLLEGEA 252
            + P P+                            GEP+ A+  YT    DE+ L E + 
Sbjct: 574 PDPPIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGGEPFQALYNYTPRNEDELELRESDV 633

Query: 253 VEVIHKLLDGWWV--IRKDDVTGYFPSMYLQK 282
           ++V+ K  DGW+V   R+    G FP  Y+++
Sbjct: 634 IDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKR 665



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 15/57 (26%), Positives = 32/57 (56%), Gaps = 2/57 (3%)

Query: 159 QTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKR--GWIPASFLEPL 213
           + ++A+ NY   +  E+ L   DV++V+EK + GW+    +  +  G  P ++++ L
Sbjct: 610 EPFQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 666



 Score = 30.0 bits (66), Expect = 3.7
 Identities = 14/53 (26%), Positives = 25/53 (47%)

Query: 230 PYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQK 282
           P  A+  + A    E+S  +G+ V ++ K+   W+        G FP  Y++K
Sbjct: 433 PAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEK 485


>gi|166064038 PAK-interacting exchange factor beta isoform a [Homo
           sapiens]
          Length = 646

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 19/69 (27%), Positives = 37/69 (53%)

Query: 162 RAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETED 221
           RA  N+++T+  E++ S GDV+ V    E GWW   +  + GW P++++  + + ++   
Sbjct: 12  RAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASEKPVS 71

Query: 222 PEPNYAGEP 230
           P+      P
Sbjct: 72  PKSGTLKSP 80



 Score = 33.9 bits (76), Expect = 0.26
 Identities = 20/62 (32%), Positives = 33/62 (53%), Gaps = 5/62 (8%)

Query: 243 DEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQK---SGQDVSQAQRQIKRGAP 299
           DE+S  +G+ + V      GWW    +  TG+FPS Y+++   S + VS     +K  +P
Sbjct: 23  DELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASEKPVSPKSGTLK--SP 80

Query: 300 PR 301
           P+
Sbjct: 81  PK 82


>gi|166064036 PAK-interacting exchange factor beta isoform d [Homo
           sapiens]
          Length = 753

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 19/69 (27%), Positives = 37/69 (53%)

Query: 162 RAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETED 221
           RA  N+++T+  E++ S GDV+ V    E GWW   +  + GW P++++  + + ++   
Sbjct: 140 RAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASEKPVS 199

Query: 222 PEPNYAGEP 230
           P+      P
Sbjct: 200 PKSGTLKSP 208



 Score = 33.9 bits (76), Expect = 0.26
 Identities = 20/62 (32%), Positives = 33/62 (53%), Gaps = 5/62 (8%)

Query: 243 DEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQK---SGQDVSQAQRQIKRGAP 299
           DE+S  +G+ + V      GWW    +  TG+FPS Y+++   S + VS     +K  +P
Sbjct: 151 DELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASEKPVSPKSGTLK--SP 208

Query: 300 PR 301
           P+
Sbjct: 209 PK 210


>gi|166064034 PAK-interacting exchange factor beta isoform c [Homo
           sapiens]
          Length = 803

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 19/69 (27%), Positives = 37/69 (53%)

Query: 162 RAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETED 221
           RA  N+++T+  E++ S GDV+ V    E GWW   +  + GW P++++  + + ++   
Sbjct: 190 RAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASEKPVS 249

Query: 222 PEPNYAGEP 230
           P+      P
Sbjct: 250 PKSGTLKSP 258



 Score = 33.9 bits (76), Expect = 0.26
 Identities = 20/62 (32%), Positives = 33/62 (53%), Gaps = 5/62 (8%)

Query: 243 DEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQK---SGQDVSQAQRQIKRGAP 299
           DE+S  +G+ + V      GWW    +  TG+FPS Y+++   S + VS     +K  +P
Sbjct: 201 DELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASEKPVSPKSGTLK--SP 258

Query: 300 PR 301
           P+
Sbjct: 259 PK 260


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,372,023
Number of Sequences: 37866
Number of extensions: 810629
Number of successful extensions: 5245
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 161
Number of HSP's successfully gapped in prelim test: 163
Number of HSP's that attempted gapping in prelim test: 4438
Number of HSP's gapped (non-prelim): 837
length of query: 390
length of database: 18,247,518
effective HSP length: 104
effective length of query: 286
effective length of database: 14,309,454
effective search space: 4092503844
effective search space used: 4092503844
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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