Guide to the Human Genome
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Search of human proteins with 21704287

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21704287 sialidase 4 [Homo sapiens]
         (496 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21704287 sialidase 4 [Homo sapiens]                               1043   0.0  
gi|117190519 sialidase 3 [Homo sapiens]                               337   1e-92
gi|222352170 neuraminidase 2 [Homo sapiens]                           228   7e-60
gi|4557791 neuraminidase precursor [Homo sapiens]                      67   5e-11
gi|222446620 hypothetical protein LOC342346 [Homo sapiens]             43   6e-04
gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens]               43   8e-04
gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sap...    42   0.001
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    42   0.001
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      41   0.002
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]               41   0.003
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 40   0.005
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    40   0.006
gi|11386197 forkhead box E3 [Homo sapiens]                             40   0.006
gi|60498978 elastin microfibril interfacer 2 [Homo sapiens]            39   0.008
gi|118344450 cell death inducing protein [Homo sapiens]                39   0.008
gi|22027541 programmed cell death 7 [Homo sapiens]                     39   0.008
gi|113416879 PREDICTED: hypothetical protein [Homo sapiens]            39   0.011
gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho...    39   0.011
gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Ho...    39   0.011
gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Ho...    39   0.011
gi|42475558 SMG-7 homolog isoform 1 [Homo sapiens]                     39   0.011
gi|42476066 SMG-7 homolog isoform 4 [Homo sapiens]                     39   0.011
gi|42476070 SMG-7 homolog isoform 2 [Homo sapiens]                     39   0.011
gi|119508426 alpha 3 type IX collagen [Homo sapiens]                   39   0.014
gi|14149675 cleavage stimulation factor, 3' pre-RNA, subunit 2, ...    39   0.014
gi|6912582 penta-EF-hand domain containing 1 [Homo sapiens]            39   0.014
gi|121114296 caudal type homeobox 1 [Homo sapiens]                     38   0.019
gi|130492454 zinc finger RNA binding protein 2 isoform 1 [Homo s...    38   0.019
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    38   0.019
gi|33286446 opioid growth factor receptor [Homo sapiens]               37   0.032

>gi|21704287 sialidase 4 [Homo sapiens]
          Length = 496

 Score = 1043 bits (2697), Expect = 0.0
 Identities = 496/496 (100%), Positives = 496/496 (100%)

Query: 1   MMSSAAFPRWLSMGVPRTPSRTVLFERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPDD 60
           MMSSAAFPRWLSMGVPRTPSRTVLFERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPDD
Sbjct: 1   MMSSAAFPRWLSMGVPRTPSRTVLFERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPDD 60

Query: 61  SHAHRLVLRRGTLAGGSVRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLGH 120
           SHAHRLVLRRGTLAGGSVRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLGH
Sbjct: 61  SHAHRLVLRRGTLAGGSVRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLGH 120

Query: 121 TPEAVQIATGRNAARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQLP 180
           TPEAVQIATGRNAARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQLP
Sbjct: 121 TPEAVQIATGRNAARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQLP 180

Query: 181 SGRLLVPAYTYRVDRRECFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAAV 240
           SGRLLVPAYTYRVDRRECFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAAV
Sbjct: 181 SGRLLVPAYTYRVDRRECFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAAV 240

Query: 241 DGGQAGSFLYCNARSPLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGSIVGFPAPAP 300
           DGGQAGSFLYCNARSPLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGSIVGFPAPAP
Sbjct: 241 DGGQAGSFLYCNARSPLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGSIVGFPAPAP 300

Query: 301 NRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPG 360
           NRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPG
Sbjct: 301 NRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPG 360

Query: 361 PRPGVSGDVGSWTLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWTE 420
           PRPGVSGDVGSWTLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWTE
Sbjct: 361 PRPGVSGDVGSWTLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWTE 420

Query: 421 PWVIYEGPSGYSDLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLREVLENVPASP 480
           PWVIYEGPSGYSDLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLREVLENVPASP
Sbjct: 421 PWVIYEGPSGYSDLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLREVLENVPASP 480

Query: 481 KPPNLGDKPRGCCWPS 496
           KPPNLGDKPRGCCWPS
Sbjct: 481 KPPNLGDKPRGCCWPS 496


>gi|117190519 sialidase 3 [Homo sapiens]
          Length = 461

 Score =  337 bits (865), Expect = 1e-92
 Identities = 194/460 (42%), Positives = 250/460 (54%), Gaps = 59/460 (12%)

Query: 26  ERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPDDSHAHRLVLRRGTLAGGSVRWGALHV 85
           + +  G+TYR+P+LL +PP  T LAF E+R +  D  A  LVLRRG   G  V+WG L  
Sbjct: 49  QEDDRGITYRIPALLYIPPTHTFLAFAEKRSTRRDEDALHLVLRRGLRIGQLVQWGPLKP 108

Query: 86  LGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLGHTPEAVQIATGRNAARLCCVASRDAG 145
           L  A L  HR+MNPCPV +  +G VFLFFI V GH  E  QI +GRNAARLC + S+DAG
Sbjct: 109 LMEATLPGHRTMNPCPVWEQKSGCVFLFFICVRGHVTERQQIVSGRNAARLCFIYSQDAG 168

Query: 146 LSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQLPSGRLLVPAYTYRVDR-RECFGKICR 204
            SW   RDLTEE IG  ++ WATFAVGPGHG+QL SGRL++PAYTY +     CF   C+
Sbjct: 169 CSWSEVRDLTEEVIGSELKHWATFAVGPGHGIQLQSGRLVIPAYTYYIPSWFFCFQLPCK 228

Query: 205 TSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAAVDGGQAGSFLYCNARSPLGSRVQAL 264
           T PHS   YSDD G TW  G L+  + + EC++A V G      LYC+AR+P   R +AL
Sbjct: 229 TRPHSLMIYSDDLGVTWHHGRLIRPMVTVECEVAEVTGRAGHPVLYCSARTPNRCRAEAL 288

Query: 265 STDEGTSFLPAERVASLPETAWGCQGSIVGF-PAPAPNRPRDDSWSVGPGSPLQPPLLGP 323
           STD G  F        L E   GCQGS+V F P   P+R +D S                
Sbjct: 289 STDHGEGFQRLALSRQLCEPPHGCQGSVVSFRPLEIPHRCQDSS---------------- 332

Query: 324 GVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPGPRPGVSGDVGSWTLALPMPFAAP 383
                                         D P      PG S         L +   A 
Sbjct: 333 ----------------------------SKDAPTIQQSSPGSS---------LRLEEEAG 355

Query: 384 PQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWTEPWVIYEGPSGYSDLASIGPAPEG 443
             S +WLLYSHP  R+ R+ +GI L+Q+PL+   W+ PW+++ GP GYSDLA++    E 
Sbjct: 356 TPSESWLLYSHPTSRKQRVDLGIYLNQTPLEAACWSRPWILHCGPCGYSDLAAL---EEE 412

Query: 444 GLVFACLYESGARTSYDEISFCTFSLREVLENVPASPKPP 483
           GL F CL+E G +   ++I+F  F+ RE+L ++      P
Sbjct: 413 GL-FGCLFECGTKQECEQIAFRLFTHREILSHLQGDCTSP 451


>gi|222352170 neuraminidase 2 [Homo sapiens]
          Length = 380

 Score =  228 bits (582), Expect = 7e-60
 Identities = 149/342 (43%), Positives = 186/342 (54%), Gaps = 36/342 (10%)

Query: 34  YRVPSLLPVPPGPTLLAFVEQRLSPDDSHAHRLVLRRGTLAGGS--VRWGALHVLGTAAL 91
           YR+P+LL +P   +LLAF EQR S  D HA  +VLRRG     +  V+W A  V+  A L
Sbjct: 20  YRIPALLYLPGQQSLLAFAEQRASKKDEHAELIVLRRGDYDAPTHQVQWQAQEVVAQARL 79

Query: 92  AEHRSMNPCPVHDAGTGTVFLFFIAVLGHTPEAVQIATGRNAARLCCVASRDAGLSWGSA 151
             HRSMNPCP++DA TGT+FLFFIA+ G   E  Q+ T  N  RLC V S D G +W S 
Sbjct: 80  DGHRSMNPCPLYDAQTGTLFLFFIAIPGQVTEQQQLQTRANVTRLCQVTSTDHGRTWSSP 139

Query: 152 RDLTEEAIGGAVQDWATFAVGPGHGVQL--PSGRLLVPAYTYRVDRRECFGKICRTSPHS 209
           RDLT+ AIG A ++W+TFAVGPGH +QL   +  L+VPAY YR         I R  P +
Sbjct: 140 RDLTDAAIGPAYREWSTFAVGPGHCLQLHDRARSLVVPAYAYRK-----LHPIQRPIPSA 194

Query: 210 FAFYSDDHGRTWRCGGLVPNLRSGECQLAAVDGGQAGSFLYCNARSPLGSRVQALSTDEG 269
           F F S DHGRTW  G  V    + ECQ+A V+ G+    +  NARS L +RVQA ST++G
Sbjct: 195 FCFLSHDHGRTWARGHFVAQ-DTLECQVAEVETGEQ-RVVTLNARSHLRARVQAQSTNDG 252

Query: 270 TSFLPAERVASLPE-TAWGCQGSIVGFPAPAPNRPRDDSWSVGPGSPLQPPLLGPGVHE- 327
             F  ++ V  L E    GCQGS++ FP+P            GPGSP Q  L     H  
Sbjct: 253 LDFQESQLVKKLVEPPPQGCQGSVISFPSPRS----------GPGSPAQWLLYTHPTHSW 302

Query: 328 -------------PPEEAAVDPRGGQVPGGPFSRLQPRGDGP 356
                        P  EA  +P         +S LQ  G GP
Sbjct: 303 QRADLGAYLNPRPPAPEAWSEPVLLAKGSCAYSDLQSMGTGP 344



 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 41/111 (36%), Positives = 60/111 (54%), Gaps = 7/111 (6%)

Query: 361 PRPGVSGDVGSWTLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWTE 420
           P  G  G V    ++ P P + P     WLLY+HP     R  +G  L+  P  P +W+E
Sbjct: 268 PPQGCQGSV----ISFPSPRSGPGSPAQWLLYTHPTHSWQRADLGAYLNPRPPAPEAWSE 323

Query: 421 PWVIYEGPSGYSDLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLRE 471
           P ++ +G   YSDL S+G  P+G  +F CLYE+     Y+EI F  F+L++
Sbjct: 324 PVLLAKGSCAYSDLQSMGTGPDGSPLFGCLYEA---NDYEEIVFLMFTLKQ 371


>gi|4557791 neuraminidase precursor [Homo sapiens]
          Length = 415

 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 66/207 (31%), Positives = 95/207 (45%), Gaps = 34/207 (16%)

Query: 33  TYRVPSLLPVPPGPTLLAFVEQR-LSPDDSHAHRLVLRRGTLAGGSVRWGALHVLGTAAL 91
           T+R+P +   P G TLLAF E R +S  D  A  + LRR ++  GS       ++    +
Sbjct: 76  TFRIPLITATPRG-TLLAFAEARKMSSSDEGAKFIALRR-SMDQGSTWSPTAFIVNDGDV 133

Query: 92  AEHRSMNPCPVHDAGTGTVFLFFIAVLGHTPEAVQIATGRNAARLCCVASRDAGLSWGSA 151
            +  ++    V D  TG VFLF+ ++  H         G   A    V S+D G+SW + 
Sbjct: 134 PDGLNLGAV-VSDVETGVVFLFY-SLCAHK-------AGCQVASTMLVWSKDDGVSWSTP 184

Query: 152 RDLTEEAIGGAVQDWATFAVGPGHGVQLP----SGRLLVPAYTYRVDRRECFGKICRTSP 207
           R+L+ + IG  V     FA GPG G+Q       GRL+V  +          G + R   
Sbjct: 185 RNLSLD-IGTEV-----FAPGPGSGIQKQREPRKGRLIVCGH----------GTLERDGV 228

Query: 208 HSFAFYSDDHGRTWRCGGLVPNLRSGE 234
             F   SDDHG +WR G  V  +  G+
Sbjct: 229 --FCLLSDDHGASWRYGSGVSGIPYGQ 253



 Score = 32.7 bits (73), Expect = 0.78
 Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 6/84 (7%)

Query: 390 LLYSHPVGRRARLHMGIRLSQSPLDPRSWTEPWV-IYEGPSGYSDLASIGPAPEG---GL 445
           + +S+P     R+++ +R S S  +  SW +  V ++ GPSGYS LA++  + +G     
Sbjct: 330 VFFSNPAHPEFRVNLTLRWSFS--NGTSWRKETVQLWPGPSGYSSLATLEGSMDGEEQAP 387

Query: 446 VFACLYESGARTSYDEISFCTFSL 469
               LYE G     + IS    S+
Sbjct: 388 QLYVLYEKGRNHYTESISVAKISV 411


>gi|222446620 hypothetical protein LOC342346 [Homo sapiens]
          Length = 1141

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 48/142 (33%), Positives = 55/142 (38%), Gaps = 19/142 (13%)

Query: 256 PLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGSIVGFPAPAPNRPRDDSWSVG---P 312
           P GS  QA+S        PA+  A  PE+A GC       P PAP         +G    
Sbjct: 290 PEGSSAQAVSLSRAQE--PAQPPALTPESAPGCTTEFA--PGPAPGTEPVPGLELGLELE 345

Query: 313 GSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQP--GPRPGVSGDVG 370
             P   P+ GP V  P    A  P  G VP  P ++  P GD P  P   P P     VG
Sbjct: 346 PVPALGPVPGPSV-TPGSLPAPWPVLGPVP-APGAQPPPLGDWPALPRRWPLPQGWPRVG 403

Query: 371 SWTL--------ALPMPFAAPP 384
           SW L          P P  APP
Sbjct: 404 SWPLWDLGVLRPTQPQPSRAPP 425


>gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens]
          Length = 540

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 29/75 (38%), Positives = 33/75 (44%), Gaps = 4/75 (5%)

Query: 297 APAPNRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVD-PRGGQVPGGPFSRLQPRGDG 355
           AP    PR D    G   P  PP   PG   PP +   D PRG Q P GP  + +P  DG
Sbjct: 167 APGDFGPRGDQGQDGAAGPPGPPG-PPGARGPPGDTGKDGPRGAQGPAGP--KGEPGQDG 223

Query: 356 PRQPGPRPGVSGDVG 370
              P   PG  G+ G
Sbjct: 224 EMGPKGPPGPKGEPG 238


>gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo
           sapiens]
          Length = 735

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 37/138 (26%), Positives = 50/138 (36%), Gaps = 23/138 (16%)

Query: 282 PETAWGCQGSIVGFPAPAPNR------------PRDDSWSVGPGSPLQPPLLGPGVHEPP 329
           P+   G Q    G  +P  +R            P    W +G   P +   LGPGV    
Sbjct: 45  PQAPEGSQAGAEGPSSPEASRSPARGAYLQSLEPSSRRWVLGGAKPAEDTSLGPGVPGTG 104

Query: 330 EEAAVDPRGGQVPGGPFSRLQPRGDGPRQPGPRPGVSGDVGSWTLALPMPFAAPPQSPTW 389
           E A      G++   P     PR   P  PGP+PG +   G     L    AAP   PT 
Sbjct: 105 EPA------GEIWYNPIPEEDPRPPAPEPPGPQPGSAESEG-----LAPQGAAPASPPTK 153

Query: 390 LLYSHPVGRRARLHMGIR 407
              +   G   RL + ++
Sbjct: 154 ASRTKSPGPARRLSIKMK 171


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens]
          Length = 2462

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 37/135 (27%), Positives = 48/135 (35%), Gaps = 38/135 (28%)

Query: 318  PPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPGPRP-------------- 363
            PP+    VHEPP E A   +       P   LQP  D P+QPG  P              
Sbjct: 957  PPIQVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKE 1016

Query: 364  ---------------GVSGDVGSWTLALPMP------FAAPPQSPTWLLYSH-PVGRRAR 401
                            + GD   WT  LP P        A P +P    +S+ P G    
Sbjct: 1017 AEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGH--P 1074

Query: 402  LHMGIRLSQSPLDPR 416
            L +G+  +  P+ PR
Sbjct: 1075 LPLGLHDTARPVLPR 1089


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 33/93 (35%), Positives = 37/93 (39%), Gaps = 16/93 (17%)

Query: 290 GSIVGFPAPA--PNRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFS 347
           G + G+P PA  P  P     S  PGSP  P   GP    P E     P G   P G   
Sbjct: 167 GGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGP----PGEPGQAGPSGPPGPPGAIG 222

Query: 348 RLQPRG-DG----PRQPGPR-----PGVSGDVG 370
              P G DG    P +PG R     PG+ G  G
Sbjct: 223 PSGPAGKDGESGRPGRPGERGLPGPPGIKGPAG 255



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 29/80 (36%), Positives = 36/80 (45%), Gaps = 11/80 (13%)

Query: 300 PNRPRDDSWSVGPGSPLQPPLLG-PGVHEPPEE----AAVDPRGGQ-VPGGPFSRLQPRG 353
           P  P     + GP  P  P   G PG+   P E     +  P+G +  PGGP +   P  
Sbjct: 700 PPGPEGGKGAAGPPGP--PGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGK 757

Query: 354 DGPRQP-GP--RPGVSGDVG 370
           DGPR P GP   PG +G  G
Sbjct: 758 DGPRGPTGPIGPPGPAGQPG 777



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 34/112 (30%), Positives = 40/112 (35%), Gaps = 21/112 (18%)

Query: 276  ERVASLPETAWGCQGSIVGFPAPAPNRPRDDSWSVG-------------PGSPLQPPLLG 322
            +R  S P    G  G      AP P  PR D    G             PG+P  P   G
Sbjct: 1063 DRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPG 1122

Query: 323  PGVHEPPEEAAVDPRGGQVPGGPFSRLQPRG-DGPR-QPGP--RPGVSGDVG 370
            P      ++ A+   G   P GP     P G DG    PGP   PG  G+ G
Sbjct: 1123 PA----GQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRG 1170



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 36/108 (33%), Positives = 44/108 (40%), Gaps = 13/108 (12%)

Query: 267 DEGTSFLPAERVASLPETAWGCQGSIVGFPAPAPNRPRDDSWSVGPGSPLQPPLLGPGVH 326
           ++G    P E  A+    A G +G+  GF  PA   P       GP      P  GP   
Sbjct: 463 EDGKDGSPGEPGANGLPGAAGERGA-PGFRGPAG--PNGIPGEKGPAGERGAP--GPA-- 515

Query: 327 EPPEEAAVDPRGGQVPGGPFSRLQPRGDG----PRQPGPRPGVSGDVG 370
             P  AA +P    VPGGP  R  P   G      +PGP PG  G+ G
Sbjct: 516 -GPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGP-PGSQGESG 561



 Score = 30.0 bits (66), Expect = 5.1
 Identities = 34/119 (28%), Positives = 43/119 (36%), Gaps = 31/119 (26%)

Query: 282 PETAWGCQGSIVGFPAPAPNRPRDDSWSVGP-GSPLQPPLLG------------------ 322
           PE  +G   ++   P  AP RP +     GP G P  P + G                  
Sbjct: 77  PEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPG 136

Query: 323 -PGVHE---------PPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPGPRPGVSGDVGS 371
            PG+ E          P+  + D + G   GG      P G  P  PGP PG SG  GS
Sbjct: 137 PPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGP-PGPPGP-PGTSGHPGS 193


>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
          Length = 1336

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 53/178 (29%), Positives = 62/178 (34%), Gaps = 21/178 (11%)

Query: 282 PETAWGCQGSI--VGFPAP----APNRPRDDSWSVGPGSP--LQPPLLGPGVHEPPEEAA 333
           P+   G QG I   G P P     P  P       GP  P  +Q P    G+   P    
Sbjct: 707 PQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQG 766

Query: 334 VDPRGGQVPGGPFSRLQPRG-DGPRQPGPRPGVSGDVGSWTLALPMPFAAPPQSPTWLLY 392
           +    G V  GP   L PRG  GP  PGPR           +  P      P  P  LL 
Sbjct: 767 IQ---GPVSQGPLMGLNPRGMQGP--PGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLG 821

Query: 393 SHPVGRRARLHMGIRLSQSPLDPRSWTEPWVIYEGPSGYSDL-----ASIGPAPEGGL 445
             P  +  R    IR  Q P    S   P     GP G          S+GP P+GG+
Sbjct: 822 HGP--QEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGM 877



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 34/112 (30%), Positives = 42/112 (37%), Gaps = 14/112 (12%)

Query: 289 QGSIVGFPAPAPNRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPG-GPFS 347
           QGS++G P      P   S    P   L PP  G     P  +   +P  G  P  GP  
Sbjct: 842 QGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIP 901

Query: 348 RLQPR----GDGPRQP--------GPRPGVSGDVGSWTLALPMPFAAPPQSP 387
             Q +    GDGPR P        GP P + G +G       +P   P Q P
Sbjct: 902 FQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPG-LGQQGAQGRIPPLNPGQGP 952


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 41/129 (31%), Positives = 51/129 (39%), Gaps = 20/129 (15%)

Query: 265 STDEGTSFLPAERVASLPETAWGCQGSIVGFPAPAPNRPRDDSWSVGPGSPLQPPLLGPG 324
           S  +GTS   +++ A  P++    Q      P P P  P        P  PL+PP  GP 
Sbjct: 378 SHSDGTSTASSQQQAP-PQSVPPSQIQAPPMPGPPPLGPP-------PAPPLRPP--GPP 427

Query: 325 VHEPPEEAAVDPRGGQVPG-----GPFSRLQPRGDGP-RQPGPRPGVSGDVGSWTLALPM 378
              PP      P   + PG     GP  RL P G  P R PGP PG    +       P 
Sbjct: 428 TGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPG----PP 483

Query: 379 PFAAPPQSP 387
           P   PP+ P
Sbjct: 484 PRGPPPRLP 492



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 28/78 (35%), Positives = 29/78 (37%), Gaps = 12/78 (15%)

Query: 296 PAPAPNRPRDDSWSVGPGSPLQPPLLGPGVHEPP--EEAAVDPRGGQV------PGGPFS 347
           P P P RP        PG P  PP  GP    PP        PR G +      P GP  
Sbjct: 460 PGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGP-- 517

Query: 348 RLQPRGDGPRQPGPRPGV 365
              P G  P  P P PGV
Sbjct: 518 --APPGLFPPAPLPNPGV 533


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
          Length = 2524

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 37/135 (27%), Positives = 49/135 (36%), Gaps = 39/135 (28%)

Query: 318  PPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPGPRP-------------- 363
            PP++   VHEPP E A   +       P   LQP  D P+QPG  P              
Sbjct: 974  PPIVTK-VHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKE 1032

Query: 364  ---------------GVSGDVGSWTLALPMP------FAAPPQSPTWLLYSH-PVGRRAR 401
                            + GD   WT  LP P        A P +P    +S+ P G    
Sbjct: 1033 AEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGH--P 1090

Query: 402  LHMGIRLSQSPLDPR 416
            L +G+  +  P+ PR
Sbjct: 1091 LPLGLHDTARPVLPR 1105


>gi|11386197 forkhead box E3 [Homo sapiens]
          Length = 319

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 77/267 (28%), Positives = 90/267 (33%), Gaps = 42/267 (15%)

Query: 156 EEAIGGAVQDWATFAVGPGHGVQLPSGR---------LLVPAYTYRVDRRECFGKICRTS 206
           EEA  G  +   T A GPG   + P  R         L+  A  +   RR     I R  
Sbjct: 42  EEAAAGRGEAAPTPAPGPGRRRRRPLQRGKPPYSYIALIAMALAHAPGRRLTLAAIYRFI 101

Query: 207 PHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAAV-DGGQAGSFLYCNARSPLGSRVQALS 265
              FAFY D   R W+   +  NL   +C +    + G  G   Y            A  
Sbjct: 102 TERFAFYRDSP-RKWQ-NSIRHNLTLNDCFVKVPREPGNPGKGNYWTL-----DPAAADM 154

Query: 266 TDEGTSFLPAERV--ASLPETAWGCQGSIVGFP----APAPNRPR---DDSWSVGPGSP- 315
            D G+     +R   A LP  A    G  + FP    APAP         S   GP  P 
Sbjct: 155 FDNGSFLRRRKRFKRAELPAHAAAAPGPPLPFPYAPYAPAPGPALLVPPPSAGPGPSPPA 214

Query: 316 ----------LQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPR----GDGPRQPGP 361
                     LQP L G G  EPP  AA D      P    +   P      D    P  
Sbjct: 215 RLFSVDSLVNLQPELAGLGAPEPPCCAAPDAAAAAFPPCAAAASPPLYSQVPDRLVLPAT 274

Query: 362 RPGVSGDVGSWTLALPMPFAA-PPQSP 387
           RPG         LAL  P AA  P SP
Sbjct: 275 RPGPGPLPAEPLLALAGPAAALGPLSP 301


>gi|60498978 elastin microfibril interfacer 2 [Homo sapiens]
          Length = 1053

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 43/135 (31%), Positives = 54/135 (40%), Gaps = 17/135 (12%)

Query: 259 SRVQALSTD--EGTSFLPAERVASLPETAWGCQGSIVGFPAPAPNRPRDDSWSVGPGS-- 314
           S V  +STD  +   F P+ +  S P  A   +  +   P PAP RP   + +  PG   
Sbjct: 767 SHVFQISTDLQDLVKFQPSAKAPSPPPPAEAPKEPLQ--PEPAPPRPSGPATAEDPGRRP 824

Query: 315 --PLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPGPRPGVSGDVGSW 372
             P +PP   P   +PP    V    GQ   GP     P G G    G   GV G  GS 
Sbjct: 825 VLPQRPPEERP--PQPPGSTGVIAETGQ--AGP-----PAGAGVSGRGLPRGVDGQTGSG 875

Query: 373 TLALPMPFAAPPQSP 387
           T+     FA  P  P
Sbjct: 876 TVPGAEGFAGAPGYP 890


>gi|118344450 cell death inducing protein [Homo sapiens]
          Length = 208

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 26/85 (30%), Positives = 30/85 (35%), Gaps = 15/85 (17%)

Query: 298 PAPNRPRDDSWSVGPGSPLQPPLLGPGVHEPP---------------EEAAVDPRGGQVP 342
           P P R         PG PL P  +GP  +EPP                +    P G   P
Sbjct: 26  PTPGRSSPAVMQPPPGMPLPPADIGPPPYEPPGHPMPQPGFIPPHMSADGTYMPPGFYPP 85

Query: 343 GGPFSRLQPRGDGPRQPGPRPGVSG 367
            GP   +     GP  PGP PG  G
Sbjct: 86  PGPHPPMGYYPPGPYTPGPYPGPGG 110


>gi|22027541 programmed cell death 7 [Homo sapiens]
          Length = 485

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 35/111 (31%), Positives = 40/111 (36%), Gaps = 12/111 (10%)

Query: 282 PETAWGCQGSIV---GFPAPAPNRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRG 338
           P   +GC    +    FP P P RP       GP      P L P +   P  +A   RG
Sbjct: 21  PPAPFGCPPPPLPSPAFPPPLPQRP-------GPFPGASAPFLQPPLALQPRASAEASRG 73

Query: 339 GQVPGGPFSRLQPRGDGPRQPGPRPGVSGDVGSWTLALPMPFAAPPQSPTW 389
           G    G F  + P    P  P  RP    D G      P P   PP SP W
Sbjct: 74  GG-GAGAFYPVPPPPLPPPPPQCRPFPGTDAGERPRP-PPPGPGPPWSPRW 122


>gi|113416879 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 175

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 23/63 (36%), Positives = 28/63 (44%), Gaps = 7/63 (11%)

Query: 318 PPLLGPGVHEPPEEAAVDPRGGQVPGG-----PFSRLQPRGDGPRQPGPRPGVSGDVGSW 372
           P + GPG+ +PP      PR G+ PG      P +R  P     R P P  G  G  G W
Sbjct: 28  PLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAG--GLRGPW 85

Query: 373 TLA 375
           T A
Sbjct: 86  TAA 88


>gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo
            sapiens]
          Length = 1751

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 28/76 (36%), Positives = 31/76 (40%), Gaps = 4/76 (5%)

Query: 297  APAPNRPRDDSWSVGPGSPLQPPLLG--PGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGD 354
            AP P   R +S   G   P  PP     PG   P   A  D   G   GGPF       D
Sbjct: 987  APGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGS--GGPFWSTARSAD 1044

Query: 355  GPRQPGPRPGVSGDVG 370
            GP+ P   PG+ GD G
Sbjct: 1045 GPQGPPGLPGLKGDPG 1060



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 47/184 (25%), Positives = 63/184 (34%), Gaps = 40/184 (21%)

Query: 298 PAPNRPRDDSWS-VGPGSPLQPPLLGPGVHEPPEEAAVD----PRGGQVPGGPFSRLQPR 352
           P P +P  D+ + V P +    P   PG  EPP E   D    P   + P  P   +   
Sbjct: 51  PLPVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEENI--A 108

Query: 353 GDGPRQPGPRPGVSGDVGSWT----------------------LALPMPFAAPPQSPTWL 390
           G G        G+   V  W                       LAL  P + P ++ T L
Sbjct: 109 GVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGTTL 168

Query: 391 LYSHPVGRRARLH---MGIRLSQSPLDPRSWTEPWVIYEGP------SGYSDLAS-IGPA 440
             S  +      H    G   + +P  P S   PW    GP      SG + L+S +G A
Sbjct: 169 WPSRGIPSSPGAHTTEAGTLPAPTP-SPPSLGRPWAPLTGPSVPPPSSGRASLSSLLGGA 227

Query: 441 PEGG 444
           P  G
Sbjct: 228 PPWG 231



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 10/79 (12%)

Query: 294  GFPAPAPNRPRDDSWSVGP-GSPLQPPLLGPGVHEPPEEAAVDPRGGQV-PGGPFSRLQP 351
            GFP PA   P+ +  S G  GSP      GP   +    +   P GG + P    ++ +P
Sbjct: 1151 GFPGPAG--PKGNLGSKGERGSP------GPKGEKGEPGSIFSPDGGALGPAQKGAKGEP 1202

Query: 352  RGDGPRQPGPRPGVSGDVG 370
               GP  P  RPG  G++G
Sbjct: 1203 GFRGPPGPYGRPGYKGEIG 1221



 Score = 29.6 bits (65), Expect = 6.6
 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 5/62 (8%)

Query: 310 VGPGSPLQPPLLGP-GVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPGPRPGVSGD 368
           +GP  P    + GP G   PP       R G+ PG P    +P   GP+     PG  GD
Sbjct: 790 LGPAGPALQTVPGPQGPPGPPGRDGTPGRDGE-PGDPGEDGKPGDTGPQ---GFPGTPGD 845

Query: 369 VG 370
           VG
Sbjct: 846 VG 847


>gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Homo
           sapiens]
          Length = 1336

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 28/76 (36%), Positives = 31/76 (40%), Gaps = 4/76 (5%)

Query: 297 APAPNRPRDDSWSVGPGSPLQPPLLG--PGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGD 354
           AP P   R +S   G   P  PP     PG   P   A  D   G   GGPF       D
Sbjct: 572 APGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGS--GGPFWSTARSAD 629

Query: 355 GPRQPGPRPGVSGDVG 370
           GP+ P   PG+ GD G
Sbjct: 630 GPQGPPGLPGLKGDPG 645



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 10/79 (12%)

Query: 294 GFPAPAPNRPRDDSWSVGP-GSPLQPPLLGPGVHEPPEEAAVDPRGGQV-PGGPFSRLQP 351
           GFP PA   P+ +  S G  GSP      GP   +    +   P GG + P    ++ +P
Sbjct: 736 GFPGPAG--PKGNLGSKGERGSP------GPKGEKGEPGSIFSPDGGALGPAQKGAKGEP 787

Query: 352 RGDGPRQPGPRPGVSGDVG 370
              GP  P  RPG  G++G
Sbjct: 788 GFRGPPGPYGRPGYKGEIG 806



 Score = 29.6 bits (65), Expect = 6.6
 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 5/62 (8%)

Query: 310 VGPGSPLQPPLLGP-GVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPGPRPGVSGD 368
           +GP  P    + GP G   PP       R G+ PG P    +P   GP+     PG  GD
Sbjct: 375 LGPAGPALQTVPGPQGPPGPPGRDGTPGRDGE-PGDPGEDGKPGDTGPQ---GFPGTPGD 430

Query: 369 VG 370
           VG
Sbjct: 431 VG 432


>gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Homo
           sapiens]
          Length = 1516

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 28/76 (36%), Positives = 31/76 (40%), Gaps = 4/76 (5%)

Query: 297 APAPNRPRDDSWSVGPGSPLQPPLLG--PGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGD 354
           AP P   R +S   G   P  PP     PG   P   A  D   G   GGPF       D
Sbjct: 752 APGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGS--GGPFWSTARSAD 809

Query: 355 GPRQPGPRPGVSGDVG 370
           GP+ P   PG+ GD G
Sbjct: 810 GPQGPPGLPGLKGDPG 825



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 10/79 (12%)

Query: 294 GFPAPAPNRPRDDSWSVGP-GSPLQPPLLGPGVHEPPEEAAVDPRGGQV-PGGPFSRLQP 351
           GFP PA   P+ +  S G  GSP      GP   +    +   P GG + P    ++ +P
Sbjct: 916 GFPGPAG--PKGNLGSKGERGSP------GPKGEKGEPGSIFSPDGGALGPAQKGAKGEP 967

Query: 352 RGDGPRQPGPRPGVSGDVG 370
              GP  P  RPG  G++G
Sbjct: 968 GFRGPPGPYGRPGYKGEIG 986



 Score = 29.6 bits (65), Expect = 6.6
 Identities = 40/162 (24%), Positives = 53/162 (32%), Gaps = 33/162 (20%)

Query: 298 PAPNRPRDDSWS-VGPGSPLQPPLLGPGVHEPPEEAAVD----PRGGQVPGGPFSRLQPR 352
           P P +P  D+ + V P +    P   PG  EPP E   D    P   + P  P   +   
Sbjct: 51  PLPVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEENI--A 108

Query: 353 GDGPRQPGPRPGVSGDVGSWT----------------------LALPMPFAAPPQSPTWL 390
           G G        G+   V  W                       LAL  P + P ++ T L
Sbjct: 109 GVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGTTL 168

Query: 391 LYSHPVGRRARLH---MGIRLSQSPLDPRSWTEPWVIYEGPS 429
             S  +      H    G   + +P  P S   PW    GPS
Sbjct: 169 WPSRGIPSSPGAHTTEAGTLPAPTP-SPPSLGRPWAPLTGPS 209



 Score = 29.6 bits (65), Expect = 6.6
 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 5/62 (8%)

Query: 310 VGPGSPLQPPLLGP-GVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPGPRPGVSGD 368
           +GP  P    + GP G   PP       R G+ PG P    +P   GP+     PG  GD
Sbjct: 555 LGPAGPALQTVPGPQGPPGPPGRDGTPGRDGE-PGDPGEDGKPGDTGPQ---GFPGTPGD 610

Query: 369 VG 370
           VG
Sbjct: 611 VG 612


>gi|42475558 SMG-7 homolog isoform 1 [Homo sapiens]
          Length = 1137

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 46/179 (25%), Positives = 65/179 (36%), Gaps = 29/179 (16%)

Query: 270 TSFLPAERVASLPETAWGCQGSIVGFPAPAPNRPRDDSWSVGPGSPLQPPLLGPGVHEPP 329
           + F+P     + P        S  GFP P    P   ++S+G G      +  PG    P
Sbjct: 644 SQFIPIHHPGAFPPLP-----SRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQP 698

Query: 330 EEAAVDPRGGQVPGG-----PFSRLQPRGDGPRQPGPRPGVSGDVGSWTLALPMPFA--- 381
              A  P G QV  G     P+S+ +P G GP   GP+          T     P A   
Sbjct: 699 --TAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQST 756

Query: 382 ---------APPQSPTWLLYSHPVGRRARLHMGI-RLSQSPLDPRSWTEPWVIYEGPSG 430
                       QSPT  + +  +G+    H G  +  Q+    + W  P V  +GP G
Sbjct: 757 SQLQVQALTQQQQSPTKAVPA--LGKSPPHHSGFQQYQQADASKQLWNPPQV--QGPLG 811


>gi|42476066 SMG-7 homolog isoform 4 [Homo sapiens]
          Length = 1049

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 46/179 (25%), Positives = 65/179 (36%), Gaps = 29/179 (16%)

Query: 270 TSFLPAERVASLPETAWGCQGSIVGFPAPAPNRPRDDSWSVGPGSPLQPPLLGPGVHEPP 329
           + F+P     + P        S  GFP P    P   ++S+G G      +  PG    P
Sbjct: 556 SQFIPIHHPGAFPPLP-----SRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQP 610

Query: 330 EEAAVDPRGGQVPGG-----PFSRLQPRGDGPRQPGPRPGVSGDVGSWTLALPMPFA--- 381
              A  P G QV  G     P+S+ +P G GP   GP+          T     P A   
Sbjct: 611 --TAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQST 668

Query: 382 ---------APPQSPTWLLYSHPVGRRARLHMGI-RLSQSPLDPRSWTEPWVIYEGPSG 430
                       QSPT  + +  +G+    H G  +  Q+    + W  P V  +GP G
Sbjct: 669 SQLQVQALTQQQQSPTKAVPA--LGKSPPHHSGFQQYQQADASKQLWNPPQV--QGPLG 723


>gi|42476070 SMG-7 homolog isoform 2 [Homo sapiens]
          Length = 1091

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 46/179 (25%), Positives = 65/179 (36%), Gaps = 29/179 (16%)

Query: 270 TSFLPAERVASLPETAWGCQGSIVGFPAPAPNRPRDDSWSVGPGSPLQPPLLGPGVHEPP 329
           + F+P     + P        S  GFP P    P   ++S+G G      +  PG    P
Sbjct: 598 SQFIPIHHPGAFPPLP-----SRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQP 652

Query: 330 EEAAVDPRGGQVPGG-----PFSRLQPRGDGPRQPGPRPGVSGDVGSWTLALPMPFA--- 381
              A  P G QV  G     P+S+ +P G GP   GP+          T     P A   
Sbjct: 653 --TAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQST 710

Query: 382 ---------APPQSPTWLLYSHPVGRRARLHMGI-RLSQSPLDPRSWTEPWVIYEGPSG 430
                       QSPT  + +  +G+    H G  +  Q+    + W  P V  +GP G
Sbjct: 711 SQLQVQALTQQQQSPTKAVPA--LGKSPPHHSGFQQYQQADASKQLWNPPQV--QGPLG 765


>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
          Length = 684

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 35/94 (37%), Positives = 40/94 (42%), Gaps = 8/94 (8%)

Query: 298 PAPNRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVD-PRGG---QVPGGPFSRLQPRG 353
           P P     +  S+GP  P  P L G G+  PP EA V  P GG   + P GP S L    
Sbjct: 94  PGPKGAPGERGSLGPPGP--PGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGP-SGLPGLP 150

Query: 354 DGPRQPGPRPGVSGDVGSWTLALPMPFAAPPQSP 387
             P  PGP PG  G +      L  P   PP  P
Sbjct: 151 GPPGPPGP-PGHPGVLPEGATDLQCPSICPPGPP 183


>gi|14149675 cleavage stimulation factor, 3' pre-RNA, subunit 2,
           64kDa, tau variant [Homo sapiens]
          Length = 616

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 48/142 (33%), Positives = 54/142 (38%), Gaps = 32/142 (22%)

Query: 294 GFPAPAPNR---PRDDSWSVGPGSPLQPPLLGPGVHEPPEE---------AAVDPRGGQV 341
           G PAP P     P     S+ PG  +QP L  PGV   P E          A  PRG   
Sbjct: 261 GIPAPGPIPAAVPGAGPGSLTPGGAMQPQLGMPGVGPVPLERGQVQMSDPRAPIPRGPVT 320

Query: 342 PGGPFSRLQPR---GDGPRQP--GPRPGVSGDVGSWTLALPMPFAAPP-QSPTWLLYSHP 395
           PGG    L PR   GD P  P  G    V+G+V       P  +  PP Q P      H 
Sbjct: 321 PGG----LPPRGLLGDAPNDPRGGTLLSVTGEVE------PRGYLGPPHQGPP---MHHA 367

Query: 396 VGRRARLHMGIRLSQSPL-DPR 416
            G   R      +   PL DPR
Sbjct: 368 SGHDTRGPSSHEMRGGPLGDPR 389


>gi|6912582 penta-EF-hand domain containing 1 [Homo sapiens]
          Length = 284

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 24/72 (33%), Positives = 28/72 (38%), Gaps = 11/72 (15%)

Query: 312 PGSPLQPPLLGPGVHEP-----PEEAAVDPRGGQVPGGPFSRLQPRGDGPRQP------G 360
           PG P  PP  G     P     P      P GG  PGGP+ +  P   G +QP      G
Sbjct: 51  PGGPYGPPAGGGPYGHPNPGMFPSGTPGGPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGG 110

Query: 361 PRPGVSGDVGSW 372
             P V  +  SW
Sbjct: 111 APPNVDPEAYSW 122


>gi|121114296 caudal type homeobox 1 [Homo sapiens]
          Length = 265

 Score = 38.1 bits (87), Expect = 0.019
 Identities = 29/101 (28%), Positives = 36/101 (35%), Gaps = 25/101 (24%)

Query: 354 DGPRQPGPRPGVSGDVGSWTLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPL 413
           D P  PGP    S  +G      P P  APPQ P +  YSH             +  +P 
Sbjct: 10  DSPVYPGPARPASLGLGPQAYGPPAPPPAPPQYPDFSSYSH-------------VEPAPA 56

Query: 414 DPRSWTEP-------WVIYEGPSGYSDLAS-----IGPAPE 442
            P +W  P       W    GP   +  AS      GP P+
Sbjct: 57  PPTAWGAPFPAPKDDWAAAYGPGPAAPAASPASLAFGPPPD 97



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 28/89 (31%), Positives = 34/89 (38%), Gaps = 16/89 (17%)

Query: 279 ASLPETAWGCQGSIVGFPAPAPNRPRDDSWSVGPGSPLQPP---LLGPGVHEPPEEAAVD 335
           A  P TAWG        P PAP      ++  GP +P   P     GP     P  A   
Sbjct: 54  APAPPTAWGA-------PFPAPKDDWAAAYGPGPAAPAASPASLAFGPPPDFSPVPAPPG 106

Query: 336 PRGG---QVPGGPFSRLQPRGDGPRQPGP 361
           P  G   Q  GGP +   P   G ++P P
Sbjct: 107 PGPGLLAQPLGGPGT---PSSPGAQRPTP 132


>gi|130492454 zinc finger RNA binding protein 2 isoform 1 [Homo
           sapiens]
          Length = 939

 Score = 38.1 bits (87), Expect = 0.019
 Identities = 44/158 (27%), Positives = 60/158 (37%), Gaps = 32/158 (20%)

Query: 230 LRSGECQLAAVDGGQAGSFLYCNARSPLGSRVQALSTDEGT---SFLPAERVAS--LPET 284
           L+SG  ++ A D GQ G+   C   SP GS   A    +     S  PA  ++S     T
Sbjct: 113 LQSG--RMTAADSGQPGTQEACGQPSPHGSHSHAQPPQQAPIVESGQPASTLSSGYTYPT 170

Query: 285 AWGCQGS-----IVGFPAP----------APNRPRDDSWSVGPGSPLQPPLLGPGVHEPP 329
           A G Q       +  +P P          AP+ P  D+      SP  PP   P    PP
Sbjct: 171 ATGVQPESSASIVTSYPPPSYNPTCTAYTAPSYPNYDASVYSAASPFYPPAQPPPPPGPP 230

Query: 330 EE---------AAVDPRGGQVPGGPFSRLQPRGDGPRQ 358
           ++         +   PR    P  P    +P+  GPRQ
Sbjct: 231 QQLPPPPAPAGSGSSPRADSKPPLPSKLPRPKA-GPRQ 267


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 38.1 bits (87), Expect = 0.019
 Identities = 22/66 (33%), Positives = 29/66 (43%), Gaps = 1/66 (1%)

Query: 298 PAPNRPRDDSWSVGPGSPLQPPLLGPGVH-EPPEEAAVDPRGGQVPGGPFSRLQPRGDGP 356
           P P  P+      GP     P L  PG H +PP     +PRGG+    P+ +   +G  P
Sbjct: 202 PGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPP 261

Query: 357 RQPGPR 362
             PG R
Sbjct: 262 GGPGGR 267



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 26/90 (28%), Positives = 36/90 (40%), Gaps = 8/90 (8%)

Query: 351 PRGDGPRQPGPRPGVSGDVGSWTLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQ 410
           P G GP Q GP+P +           P P   PPQ P      H      + H   +  Q
Sbjct: 46  PMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPP----PHQPPPHPQPH---QQQQ 98

Query: 411 SPLDPRSWTEPWVIYEGPSGYSDLASIGPA 440
            P  P+  ++P V+ +GP     + S  PA
Sbjct: 99  PPPPPQDSSKP-VVAQGPGPAPGVGSAPPA 127



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 29/94 (30%), Positives = 36/94 (38%), Gaps = 11/94 (11%)

Query: 296 PAPAPNRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPG-GPFSRLQPRGD 354
           P P P  P   + S  PG+P   P        PP+     P    VPG GP  +  P   
Sbjct: 147 PGPTPTPPPAVT-SAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPG 205

Query: 355 GPR----QPGPRPGVSGDVGSWTLALPMPFAAPP 384
           GP+      GP+PG     G   L+ P     PP
Sbjct: 206 GPKGGKMPGGPKPG-----GGPGLSTPGGHPKPP 234



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 29/101 (28%), Positives = 38/101 (37%), Gaps = 16/101 (15%)

Query: 287 GCQGSIVGFPAPAPNRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPF 346
           G  G     P P P++ +          P QPP   P  H+PP      P   Q P  P 
Sbjct: 52  GQSGPKPPIPPPPPHQQQQQP------PPQQPPPQQPPPHQPPPHP--QPHQQQQPPPP- 102

Query: 347 SRLQPRGDGPRQPGPRPGVSGDVGSWTLALPMPFAAPPQSP 387
            +   +    + PGP PGV         A P   +APP +P
Sbjct: 103 PQDSSKPVVAQGPGPAPGVGS-------APPASSSAPPATP 136


>gi|33286446 opioid growth factor receptor [Homo sapiens]
          Length = 677

 Score = 37.4 bits (85), Expect = 0.032
 Identities = 30/94 (31%), Positives = 34/94 (36%), Gaps = 6/94 (6%)

Query: 296 PAPAPNRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDG 355
           P P P  P  D  +  P     P   GP   EP E  +  P  G  P GP    +P    
Sbjct: 562 PGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETP--GPRPAGPAGD-EPAESP 618

Query: 356 PRQPGPRPGVSGDVGSWTLALPMPFAAP-PQSPT 388
              PGPRP  +G  G      P     P P  PT
Sbjct: 619 SETPGPRP--AGPAGDEPAESPSETPGPSPAGPT 650



 Score = 35.8 bits (81), Expect = 0.092
 Identities = 25/77 (32%), Positives = 29/77 (37%), Gaps = 3/77 (3%)

Query: 287 GCQGSIVGFPAPAPNRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPF 346
           G  GS    P P+P  P  D  +  P     P   GP   EP E  +  P  G  P GP 
Sbjct: 513 GTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETP--GPRPAGPA 570

Query: 347 SRLQPRGDGPRQPGPRP 363
              +P       PGP P
Sbjct: 571 GD-EPAESPSETPGPSP 586


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.138    0.453 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,953,693
Number of Sequences: 37866
Number of extensions: 1657920
Number of successful extensions: 6636
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 418
Number of HSP's that attempted gapping in prelim test: 5644
Number of HSP's gapped (non-prelim): 1354
length of query: 496
length of database: 18,247,518
effective HSP length: 106
effective length of query: 390
effective length of database: 14,233,722
effective search space: 5551151580
effective search space used: 5551151580
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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