Guide to the Human Genome
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Search of human proteins with 11386161

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11386161 alpha 2 type IX collagen [Homo sapiens]
         (689 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11386161 alpha 2 type IX collagen [Homo sapiens]                  1495   0.0  
gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo s...   777   0.0  
gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo s...   771   0.0  
gi|119508426 alpha 3 type IX collagen [Homo sapiens]                  673   0.0  
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]     573   e-163
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]               571   e-163
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      555   e-158
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   548   e-156
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]      548   e-156
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   546   e-155
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     545   e-155
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   543   e-154
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     540   e-153
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]   539   e-153
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   539   e-153
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   539   e-153
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   539   e-153
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   537   e-152
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   537   e-152
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]              526   e-149
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]    523   e-148
gi|48762934 alpha 2 type I collagen [Homo sapiens]                    518   e-147
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...   516   e-146
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...   516   e-146
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...   516   e-146
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]       510   e-144
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]        507   e-143
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         506   e-143
gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]              502   e-142
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...   499   e-141

>gi|11386161 alpha 2 type IX collagen [Homo sapiens]
          Length = 689

 Score = 1495 bits (3870), Expect = 0.0
 Identities = 689/689 (100%), Positives = 689/689 (100%)

Query: 1   MAAATASPRSLLVLLQVVVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAG 60
           MAAATASPRSLLVLLQVVVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAG
Sbjct: 1   MAAATASPRSLLVLLQVVVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAG 60

Query: 61  PPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGP 120
           PPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGP
Sbjct: 61  PPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGP 120

Query: 121 PGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPP 180
           PGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPP
Sbjct: 121 PGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPP 180

Query: 181 GMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMA 240
           GMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMA
Sbjct: 181 GMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMA 240

Query: 241 GPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGAT 300
           GPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGAT
Sbjct: 241 GPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGAT 300

Query: 301 GPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLP 360
           GPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLP
Sbjct: 301 GPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLP 360

Query: 361 GFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQ 420
           GFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQ
Sbjct: 361 GFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQ 420

Query: 421 GLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPS 480
           GLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPS
Sbjct: 421 GLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPS 480

Query: 481 GDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEV 540
           GDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEV
Sbjct: 481 GDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEV 540

Query: 541 AVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKR 600
           AVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKR
Sbjct: 541 AVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKR 600

Query: 601 GEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGL 660
           GEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGL
Sbjct: 601 GEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGL 660

Query: 661 PGFCEPAACLGASAYASARLTEPGSIKGP 689
           PGFCEPAACLGASAYASARLTEPGSIKGP
Sbjct: 661 PGFCEPAACLGASAYASARLTEPGSIKGP 689


>gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo
           sapiens]
          Length = 678

 Score =  777 bits (2007), Expect = 0.0
 Identities = 376/667 (56%), Positives = 432/667 (64%), Gaps = 5/667 (0%)

Query: 3   AATASPRSLLVLLQVVVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPP 62
           A TA  R  L LL + +   A  RGPPGE+GPPGPPGPPGVPG DGIDGD GP G  GPP
Sbjct: 2   AWTARDRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPP 61

Query: 63  GPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPG 122
           GP GEPGK G  G  G PG DGLTG  G PG +G  G KG+PG+PG  G PG G  GPPG
Sbjct: 62  GPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPG 121

Query: 123 PPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGM 182
           PPG  GLPGE+G  GP GDPG  GP GPPGPPG  G  G   G     D LCP  CPPG 
Sbjct: 122 PPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDG-----DPLCPNACPPGR 176

Query: 183 KGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGP 242
            G PGL G++GH G +G +G+PG QG  G +GD G  GE G  GPPG QG+RG  G+ G 
Sbjct: 177 SGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGD 236

Query: 243 KGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGP 302
           KGE G  G  G  G  G  G PG++G RGPPG AG KGD G+ G RG  G+ GPKG TG 
Sbjct: 237 KGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGL 296

Query: 303 PGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGF 362
           PG++G+DG PG PG KG  G+ G PG  G QGL GVPG PG KG  G++G  G  G PG 
Sbjct: 297 PGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQ 356

Query: 363 SGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGL 422
            G  GK G+ GP GE+GP+G  G  G +GE GPVG PG  G+ G  G  G PG+PGP GL
Sbjct: 357 MGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGL 416

Query: 423 PGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGD 482
           PG+KGD+G  G+ GP+G+ G  G  G  GE+GE G+ G PGPKG  G  GEPG  GP G 
Sbjct: 417 PGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGS 476

Query: 483 AGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAV 542
            G PGV+G  GPPGPRG+ G +G  G PG QG  GR  TDQHI  V ++++QE  AE+A 
Sbjct: 477 RGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAA 536

Query: 543 SAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGE 602
           S KR   GA G+ G PGPPGPPG PG+ G  G  G RG+PGI G  G +G  GPKG  GE
Sbjct: 537 SLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGE 596

Query: 603 KGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPG 662
           KG+ G  GRG  G+PG  G+PG PG      NG+DG+RG PG  G  G PG PGP GLPG
Sbjct: 597 KGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656

Query: 663 FCEPAAC 669
           FCEPA+C
Sbjct: 657 FCEPASC 663



 Score =  394 bits (1013), Expect = e-109
 Identities = 233/592 (39%), Positives = 283/592 (47%), Gaps = 85/592 (14%)

Query: 143 GPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILG 202
           GP G  GPPGPPG PG PG I G++G          P G  GPPG  G  G  G  G  G
Sbjct: 26  GPPGEQGPPGPPGPPGVPG-IDGIDGDRG-------PKGPPGPPGPAGEPGKPGAPGKPG 77

Query: 203 DPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPG--MAGPKGETGPHGYKGMVGAIGA 260
            PG  G  GP G  G+ G +G  G PG  G RG+PG  + GP G  G  G  G +G +G 
Sbjct: 78  TPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGP 137

Query: 261 TGPPGEEGPRGPPGRAGEKGD------------------EGSPGIRGPQGITGPKGATGP 302
            G PG  GP GPPG  G +G                    G PG+ G +G  G KG  G 
Sbjct: 138 VGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGE 197

Query: 303 PGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGF 362
           PG  G  G  G  G  G  G  G PG+ G +G+ G+ G  G KG  G  GEPGPQGLPG 
Sbjct: 198 PGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGA 257

Query: 363 SG------PPGKEGEPGPRGEIGPQGIMGQKGDQGE------------------RGPVGQ 398
            G      PPG+ G  G RG  G +GI G  G +G+                  +G  G+
Sbjct: 258 PGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGK 317

Query: 399 PGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGE 458
           PGP G  G +G  G PGIPG +G+ G KG  G+PGK G  G  G PG  G PGE G +G 
Sbjct: 318 PGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGP 377

Query: 459 SGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGR 518
            G PG +G+ G  G PG PG  G  G+PG+ G PGPPG  G+ G+RGV G+PG +G +G 
Sbjct: 378 QGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGA 437

Query: 519 DATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGP 578
              +    +      + +L ++ +   + + G  G  G  GP G  G PG +GP G PGP
Sbjct: 438 SGEEGEAGE------RGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGP 491

Query: 579 RGVPGIVGAVGQIGNTGPKGKRGEKGDPGEV-------------------GRGHPGMPGP 619
           RGV G  GA G  G  GP G+        +V                     G  G+PG 
Sbjct: 492 RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGR 551

Query: 620 PGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLG 671
           PG PG PG PG+         G PG  G  G PG+ GP G  G   P   LG
Sbjct: 552 PGPPGPPGPPGE--------NGFPGQMGIRGLPGIKGPPGALGLRGPKGDLG 595



 Score =  317 bits (811), Expect = 3e-86
 Identities = 192/465 (41%), Positives = 224/465 (48%), Gaps = 76/465 (16%)

Query: 234 RGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGI 293
           RG PG  GP G  GP G  G+ G  G  GP G  GP GP G  G+ G  G PG  G  G+
Sbjct: 25  RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGL 84

Query: 294 TGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGE 353
           TGP G+ G  G  G+ G PG PG +G  G+          G+ G PG PGT G PG+ G 
Sbjct: 85  TGPDGSPGSIGSKGQKGEPGVPGSRGFPGR----------GIPGPPGPPGTAGLPGELGR 134

Query: 354 PGPQGLPGFSGPPGKEGEPGPRGEIGPQ------------------GIMGQKGDQGERGP 395
            GP G PG  GPPG  G PGPRG IG                    G+ G +G +G +G 
Sbjct: 135 VGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGE 194

Query: 396 VGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGE 455
           +G+PG QG +G +G+QG  G  G QG PG +G +G  G       VGD G  G  G  GE
Sbjct: 195 IGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGI------VGDKGEKGARGLDGE 248

Query: 456 KGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGV 515
            G  G PG  G QG RG PG  GP GD GA G +G PG PGP+G   + G+PG  GR G+
Sbjct: 249 PGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKG---DTGLPGVDGRDGI 305

Query: 516 EGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGH 575
            G   T                            G  G  GPPG  G  G PG  G  G 
Sbjct: 306 PGMPGTK---------------------------GEPGKPGPPGDAGLQGLPGVPGIPGA 338

Query: 576 PGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-RGHPGMPG------PPGIPGLPGR 628
            G  G  G  GA G+ G  G  GK G++G PGEVG RG  G+PG      P G PGLPG+
Sbjct: 339 KGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGK 398

Query: 629 PGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGAS 673
            G       G  G PG PG  G PG+ G  G+ G   P    GAS
Sbjct: 399 LGSL-----GSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGAS 438



 Score =  285 bits (728), Expect = 1e-76
 Identities = 179/448 (39%), Positives = 211/448 (47%), Gaps = 112/448 (25%)

Query: 26  RGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGP---------------PGPKGEPGK 70
           +G  G RG  G PGP G+PG+ G  G  GPPG+AGP               PGPKG+ G 
Sbjct: 237 KGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGL 296

Query: 71  AGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPG-------------PGF 117
            G DG DG PG+ G  G  G+PGP G  G++G PG+PG PG  G             PG 
Sbjct: 297 PGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQ 356

Query: 118 AGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTN 177
            G  G PG  G PGE+G RGP+G PG  G  GP G PG PG+ G++    GS        
Sbjct: 357 MGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSL----GSPGL----- 407

Query: 178 CPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQG------IPGPPG-- 229
             PG+ GPPGL G+KG    RG++G+PG +G+ G  G+ G +GE+G      +PGP G  
Sbjct: 408 --PGLPGPPGLPGMKGD---RGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSA 462

Query: 230 ----------PQGIRGYPGMAGPKGETGPHGYKGMVGAIG-------------------- 259
                     P+G RG PG+ GP+G  GP G +G  GA G                    
Sbjct: 463 GNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQV 522

Query: 260 ----------------------ATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPK 297
                                 ATG PG  GP GPPG  GE G  G  GIRG  GI GP 
Sbjct: 523 CMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPP 582

Query: 298 GATG---PPGINGKDGTPGTPGM--KGSAGQAGQPGSPG-----HQGLAGVPGQPGTKGG 347
           GA G   P G  G+ G  G PG    G  G  G PG PG       G  G  G PG  G 
Sbjct: 583 GALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGI 642

Query: 348 PGDQGEPGPQGLPGFSGPPGKEGEPGPR 375
           PG  G PGP GLPGF  P     + G R
Sbjct: 643 PGVPGPPGPPGLPGFCEPASCTMQAGQR 670



 Score =  248 bits (632), Expect = 2e-65
 Identities = 153/358 (42%), Positives = 179/358 (50%), Gaps = 44/358 (12%)

Query: 345 KGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGR 404
           +G PG+QG PGP G PG  G  G +G+ GP+G  GP G  G+ G  G  G  G PG  G 
Sbjct: 25  RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGL 84

Query: 405 QGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGP 464
            GP G  G  G  G +G PGV G +G PG+  P G  G PG AGLPGE G  G  G+PG 
Sbjct: 85  TGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIP-GPPGPPGTAGLPGELGRVGPVGDPGR 143

Query: 465 KGQQGVRGEPGYPGPSGDAG------------APGVQGYPGPPGPRGLAGNRGVPGQPGR 512
           +G  G    PG PGP G  G             PG  GYPG PG RG  G +G  G+PGR
Sbjct: 144 RGPPG---PPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGR 200

Query: 513 QGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGP 572
           QG +G +              Q +L EV         GA G+ G  G  G  G  G +G 
Sbjct: 201 QGHKGEEGD------------QGELGEVGAQGPP---GAQGLRGITGIVGDKGEKGARGL 245

Query: 573 HGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-RGHPGMPGPPGIPGLPGRPGQ 631
            G PGP+G+PG   A G  G  GP G+ G KGD G  G RG PG+PGP G  GLPG    
Sbjct: 246 DGEPGPQGLPG---APGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPG---- 298

Query: 632 AINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASARLTEPGSIKGP 689
            ++G+DG  G PG  GE G+PG PG  GL G        GA   A     E GS   P
Sbjct: 299 -VDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAG----EKGSTGAP 351


>gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo
           sapiens]
          Length = 921

 Score =  771 bits (1992), Expect = 0.0
 Identities = 368/644 (57%), Positives = 422/644 (65%), Gaps = 5/644 (0%)

Query: 26  RGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGL 85
           RGPPGE+GPPGPPGPPGVPG DGIDGD GP G  GPPGP GEPGK G  G  G PG DGL
Sbjct: 268 RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGL 327

Query: 86  TGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDPGPD 145
           TG  G PG +G  G KG+PG+PG  G PG G  GPPGPPG  GLPGE+G  GP GDPG  
Sbjct: 328 TGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRR 387

Query: 146 GPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPG 205
           GP GPPGPPG  G  G   G     D LCP  CPPG  G PGL G++GH G +G +G+PG
Sbjct: 388 GPPGPPGPPGPRGTIGFHDG-----DPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPG 442

Query: 206 HQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPG 265
            QG  G +GD G  GE G  GPPG QG+RG  G+ G KGE G  G  G  G  G  G PG
Sbjct: 443 RQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPG 502

Query: 266 EEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAG 325
           ++G RGPPG AG KGD G+ G RG  G+ GPKG TG PG++G+DG PG PG KG  G+ G
Sbjct: 503 DQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPG 562

Query: 326 QPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMG 385
            PG  G QGL GVPG PG KG  G++G  G  G PG  G  GK G+ GP GE+GP+G  G
Sbjct: 563 PPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQG 622

Query: 386 QKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPG 445
             G +GE GPVG PG  G+ G  G  G PG+PGP GLPG+KGD+G  G+ GP+G+ G  G
Sbjct: 623 LPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASG 682

Query: 446 VAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRG 505
             G  GE+GE G+ G PGPKG  G  GEPG  GP G  G PGV+G  GPPGPRG+ G +G
Sbjct: 683 EEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQG 742

Query: 506 VPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPG 565
             G PG QG  GR  TDQHI  V ++++QE  AE+A S KR   GA G+ G PGPPGPPG
Sbjct: 743 ATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPG 802

Query: 566 YPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGL 625
            PG+ G  G  G RG+PGI G  G +G  GPKG  GEKG+ G  GRG  G+PG  G+PG 
Sbjct: 803 PPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGD 862

Query: 626 PGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAAC 669
           PG      NG+DG+RG PG  G  G PG PGP GLPGFCEPA+C
Sbjct: 863 PGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASC 906



 Score =  390 bits (1003), Expect = e-108
 Identities = 246/632 (38%), Positives = 289/632 (45%), Gaps = 128/632 (20%)

Query: 23  AQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPG---------KAGP 73
           A + G  G  GP G P            G  GPPG  GPPGP+G  G          A P
Sbjct: 369 AGLPGELGRVGPVGDP------------GRRGPPGPPGPPGPRGTIGFHDGDPLCPNACP 416

Query: 74  DGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEI 133
            G  G PG+ G+ G KG  G +G PG +G  G  G  G  G    G  GPPG  GL G  
Sbjct: 417 PGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGE--VGAQGPPGAQGLRGIT 474

Query: 134 GIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKG 193
           GI G KG+ G  G  G PGP G PG PG                   G +GPPG  G KG
Sbjct: 475 GIVGDKGEKGARGLDGEPGPQGLPGAPG-----------------DQGQRGPPGEAGPKG 517

Query: 194 HAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKG 253
             G  G  G P   G PGPKGD G  G  G  G PG  G +G PG  GP G+ G  G  G
Sbjct: 518 DRGAEGARGIP---GLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPG 574

Query: 254 MVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPG 313
           + G  GA G  GE+G  G PG+ G+ G+ G PG +GP G  GP+G  G PG  G+ G  G
Sbjct: 575 VPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVG 634

Query: 314 TPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPG 373
           +PG+ G  G  G PG P   GL G PG PG KG  G  GEPGP+G  G S   G+EGE G
Sbjct: 635 SPGLPGKLGSLGSPGLP---GLPGPPGLPGMKGDRGVVGEPGPKGEQGAS---GEEGEAG 688

Query: 374 PRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPG 433
            RGE+G  G+ G KG  G  G  G  GP+G +G  G +GP G PGP+G+ G +G  G PG
Sbjct: 689 ERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPG 748

Query: 434 KTGPRGKV------------------GDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPG 475
             GP G+                    +   +    + G  G  G PGP G  G  GE G
Sbjct: 749 VQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENG 808

Query: 476 YPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQE 535
           +PG  G  G PG++   GPPG  GL G +G  G+ G +G  GR                 
Sbjct: 809 FPGQMGIRGLPGIK---GPPGALGLRGPKGDLGEKGERGPPGRGPN-------------- 851

Query: 536 QLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTG 595
                         G  G +G PG PGP  Y G+ G  G  GP GV GI           
Sbjct: 852 --------------GLPGAIGLPGDPGPASY-GRNGRDGERGPPGVAGI----------- 885

Query: 596 PKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPG 627
                             PG+PGPPG PGLPG
Sbjct: 886 ------------------PGVPGPPGPPGLPG 899



 Score =  379 bits (974), Expect = e-105
 Identities = 242/621 (38%), Positives = 284/621 (45%), Gaps = 124/621 (19%)

Query: 129 LPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGL 188
           LP  I       + GP G  GPPGPPG P                          G PG+
Sbjct: 255 LPARITPSQTTDERGPPGEQGPPGPPGPP--------------------------GVPGI 288

Query: 189 QGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGP 248
            G+ G  G +G  G PG  G+PG  G  G  G  G  G  GP G  G  G  G KGE G 
Sbjct: 289 DGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGV 348

Query: 249 HGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGIN-- 306
            G +G  G  G  GPPG  G  G PG  G  G  G PG RGP G  GP G  G  G +  
Sbjct: 349 PGSRGFPGR-GIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDG 407

Query: 307 ----------GKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGP 356
                     G+ G PG PGM+G  G  G+ G PG QG  G  G  G  G  G QG PG 
Sbjct: 408 DPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGA 467

Query: 357 QGLPGFSGPPGKEGEPGPRG---EIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGP 413
           QGL G +G  G +GE G RG   E GPQG+ G  GDQG+RGP G+ GP+G +G +G +G 
Sbjct: 468 QGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGI 527

Query: 414 PGIPGPQG------------LPGVKGDKGSPGKTGPRGKVGD---PGVAGLPGEKG---E 455
           PG+PGP+G            +PG+ G KG PGK GP G  G    PGV G+PG KG   E
Sbjct: 528 PGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGE 587

Query: 456 KGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGP------------PGPRGLAGN 503
           KG +G PG  GQ G  G+PG  GP G+ G  G QG PG             PG  G  G+
Sbjct: 588 KGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGS 647

Query: 504 RGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGP 563
            G+PG PG  G+ G       + +   K  Q    E   + +R  LG +G+ GP G  G 
Sbjct: 648 PGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGN 707

Query: 564 PGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPG-- 621
           PG PG +GP G    RG+PG+ G        GP G RG +G+ G  G   PG+ GPPG  
Sbjct: 708 PGEPGLRGPEGS---RGLPGVEGP------RGPPGPRGVQGEQGATGL--PGVQGPPGRA 756

Query: 622 -------------------------------IPGLPGRPGQAINGKDGDRGSPGAPGEAG 650
                                            GLPGRPG          G PG PGE G
Sbjct: 757 PTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPP--------GPPGPPGENG 808

Query: 651 RPGLPGPVGLPGFCEPAACLG 671
            PG  G  GLPG   P   LG
Sbjct: 809 FPGQMGIRGLPGIKGPPGALG 829



 Score =  112 bits (281), Expect = 9e-25
 Identities = 73/168 (43%), Positives = 83/168 (49%), Gaps = 32/168 (19%)

Query: 538 AEVAVSAKREALGAVGMMGPPGPPGPPGYP---------GKQGPHGHPGPRGVPGIVGAV 588
           A +  S   +  G  G  GPPGPPGPPG P         G +GP G PGP G PG  GA 
Sbjct: 257 ARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAP 316

Query: 589 GQIGN------TGPK------GKRGEKGDPGEVG-RGHP--GMPGPPGIPGLPGRPGQAI 633
           G+ G       TGP       G +G+KG+PG  G RG P  G+PGPPG PG  G PG+  
Sbjct: 317 GKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGEL- 375

Query: 634 NGKDGDRGSPGAPGEAGRPGLPGPVGLPGF------CEPAACLGASAY 675
            G+ G  G PG  G  G PG PGP G  GF      C  A   G S Y
Sbjct: 376 -GRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGY 422



 Score =  102 bits (254), Expect = 1e-21
 Identities = 61/139 (43%), Positives = 66/139 (47%), Gaps = 16/139 (11%)

Query: 20  LALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGK 79
           +A +  R   G  G PG PGPPG PG  G +G  G  G  G PG KG PG  G  GP G 
Sbjct: 777 MAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGD 836

Query: 80  PGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPK 139
            G  G  G  G  GP G+PG  G PG PGP      G  G  GPPG  G+P         
Sbjct: 837 LGEKGERGPPGR-GPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIP--------- 886

Query: 140 GDPGPDGPSGPPGPPGKPG 158
                 G  GPPGPPG PG
Sbjct: 887 ------GVPGPPGPPGLPG 899



 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 45/99 (45%), Positives = 52/99 (52%), Gaps = 11/99 (11%)

Query: 16  QVVVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDG 75
           Q+ +  L  I+GPPG  G  GP G  G        G+ GPPG+    GP G PG  G  G
Sbjct: 812 QMGIRGLPGIKGPPGALGLRGPKGDLGE------KGERGPPGR----GPNGLPGAIGLPG 861

Query: 76  PDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPG 114
             G P   G  G  GE GP G+ G+ G PG PGPPGLPG
Sbjct: 862 DPG-PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899


>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
          Length = 684

 Score =  673 bits (1736), Expect = 0.0
 Identities = 341/668 (51%), Positives = 408/668 (61%), Gaps = 16/668 (2%)

Query: 11  LLVLLQVVVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGK 70
           LL+L +++  A AQ  G PG   PPGPPGPPG PG DGIDG+ GPPG  GPPGPKG PGK
Sbjct: 13  LLLLGELLAAAGAQRVGLPG---PPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGK 69

Query: 71  AGPDGP---DGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPV 127
            G  G     G PG+DGLTG  G PGP G PG +G  G PGPPGL G G  GPPG  G  
Sbjct: 70  PGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVS 129

Query: 128 GLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPG 187
           G PG IG+RGP G  G  G  GPPGPPG PG PG +   EG+ D  CP+ CPPG  GPPG
Sbjct: 130 GPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLP--EGATDLQCPSICPPGPPGPPG 187

Query: 188 LQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGP---PGPQGIRGYPGMAGPKG 244
           + G KG  G +G   + G  GK G KGD G  G  G+PG     GP+G+RG PG  GP G
Sbjct: 188 MPGFKGPTGYKG---EQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPG 244

Query: 245 ETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPG 304
           + GP G++G  G  GA G  G+ G RGP G  G KGD G PG +G  G+ GP G  G PG
Sbjct: 245 DRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPG 304

Query: 305 INGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSG 364
            +G++G PG  G KG AG+ G PG  G  GL G+PG+ G+KG  G++G  G  G  G SG
Sbjct: 305 KDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSG 364

Query: 365 PPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPG 424
            PG  G+ G  GE G  G  G  G  G +GP G PG +G QG KG  G PG+PGPQGL G
Sbjct: 365 EPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRG 424

Query: 425 VKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAG 484
             GD+G  G  GP+G  G  G  GLPG+KGE G SG  GPKG+ G RGE G  G  G  G
Sbjct: 425 DVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNG 484

Query: 485 APGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSA 544
             GVQG PGPPGP GL G  GVPG  G+ GV G++A++Q I ++   M+ EQ+A++A   
Sbjct: 485 TSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHL 544

Query: 545 KREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKG 604
           ++    A G +G PGP GPPG PG  G  GHPG RG PG  G  G++G+ GP+G +G++G
Sbjct: 545 RKPL--APGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRG 602

Query: 605 DPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFC 664
           D G  G G  G  G  G  G  G PG + +G+DG  G PG PG+ G PG  G  G PG C
Sbjct: 603 DKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGIC 662

Query: 665 EPAACLGA 672
           + +AC GA
Sbjct: 663 DTSACQGA 670



 Score =  388 bits (997), Expect = e-108
 Identities = 252/595 (42%), Positives = 289/595 (48%), Gaps = 66/595 (11%)

Query: 127 VGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPP 186
           VGLPG  G  GP G PG DG  G  GPPG PG                    PPG KG P
Sbjct: 28  VGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPG--------------------PPGPKGAP 67

Query: 187 GLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGI--RGYPGMAGPKG 244
           G  G  G AG  G+ G  G  G+ GP G  GA GE+G  GPPGP G+  +G PG  G  G
Sbjct: 68  GKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAG 127

Query: 245 ETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKG--DEGS----------PGIRGPQG 292
            +GP G  G+ G  G +G PG  GP GPPG  G  G   EG+          PG  GP G
Sbjct: 128 VSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPG 187

Query: 293 ITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQG 352
           + G KG TG  G  G+ G  G  G  G  G AG PGS G QG  G+ G PG  G PGD+G
Sbjct: 188 MPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRG 247

Query: 353 EPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQG 412
             G +G PG  G PGK G+   RGE GP+G  G KGD G  GP G PG  G   P GE G
Sbjct: 248 PIGFRGPPGIPGAPGKAGD---RGERGPEGFRGPKGDLGRPGPKGTPGVAG---PSGEPG 301

Query: 413 PPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRG 472
            PG  G  G+PG+ G KG  G+ G  G+ G  G+ GLPG  G KGE GE G  G+ G  G
Sbjct: 302 MPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAG 361

Query: 473 EPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKM 532
             G PG  GDAG PG +G  G  G  G  G +G PG PG +G +G+  +   + D  L  
Sbjct: 362 PSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGS---MGDPGLPG 418

Query: 533 LQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIG 592
            Q    +V       A G  G  G  G  G PG  G+ GP G  GP+G  G  G +G  G
Sbjct: 419 PQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKG 478

Query: 593 NTGPKGKRGEKGDPGEVGR-GHPGMPGPPGIPGLPGRPG-----QAINGKDGDRGS---- 642
             GP G  G +G PG  G  G  G+PG PGI G PG PG     Q I    G   S    
Sbjct: 479 TQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIA 538

Query: 643 --------PGAPGEAGRPGL---PGPVGLPGFCEPAACLGASAY--ASARLTEPG 684
                   P APG  GRPG    PGP G PG        G   Y   +  L +PG
Sbjct: 539 QLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPG 593


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score =  573 bits (1476), Expect = e-163
 Identities = 328/721 (45%), Positives = 384/721 (53%), Gaps = 69/721 (9%)

Query: 25   IRGPPGERGPPGPPGPPGVPGSDGIDG------DNGPPGKAGPPGPKGEPGKAGPDGPDG 78
            ++G PGE GP GP GPPG  G +G  G      + G PG  G PGP G PG  G  G  G
Sbjct: 366  LQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRG 425

Query: 79   KPGIDGLTGAKG------EPGPMGIPGVKGQPGLPGPPGLPG---PGFAGPPGPPGPVGL 129
             PG DG  G KG       PGP+G  G  G PGLPGPPG      PG  G PG PGP+G 
Sbjct: 426  TPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGT 485

Query: 130  ------PGEIGIRGPKGDPG-----PDGPSGPPGPPGKPGRPGTI--------QGLEGSA 170
                  PG  G  G +GDPG     P GPSGPPG  G PG  G           G +G +
Sbjct: 486  KGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLS 545

Query: 171  DFLCP-----------TNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGAS 219
              L P            +CPPG  G PGL G K   G +G+ G PG +G  G KG+ G  
Sbjct: 546  SLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFK---GDKGVPGKPGREGTEGKKGEAGPP 602

Query: 220  GEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEK 279
            G  G PG  GPQG +G  G  G  G+ G  G+ G+ G +G  G PG  G  G  G AG  
Sbjct: 603  GLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPP 662

Query: 280  GDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVP 339
            G +GSPG  GP G  GP G  G PG  GK+G  G PG  G  G+AG+PG PG +G  G P
Sbjct: 663  GIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPP 722

Query: 340  ---GQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPV 396
               G  G  G PG +GE G  GLPG  G PGK+G+ GP G  GPQG  G  G  G  G  
Sbjct: 723  GFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSP 782

Query: 397  GQPGPQ---GRQGPKGEQGPPGIP---GPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLP 450
            G+PGP    G++G KGE G PG+P   GP+G PG  G+KG PGK G  GK G+PG  G  
Sbjct: 783  GEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGER 842

Query: 451  GEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQP 510
            G+ G KG+ G PG KGQ    G+PG PG  G  G  G QG PG  GP G  G  G PG P
Sbjct: 843  GDPGIKGDKGPPGGKGQP---GDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFP 899

Query: 511  GRQGVEGRDATDQHIVDVAL-KMLQEQLAEVAVSAKREAL-GAVGMMGPPGPPGPPGYPG 568
            G +G      T + ++   L K L+ +LA +        +  + G  GPPGPPG  G PG
Sbjct: 900  GLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPG 959

Query: 569  KQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGR 628
            + GP G PG  G  G+ G  G I   GPKG+RG KGDPG  G G  G  GPPGIPG PG 
Sbjct: 960  RAGPMGEPGRPGQGGLEGPSGPI---GPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGE 1016

Query: 629  PGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASARLTEPGSIKG 688
            PG A +G  G  G  G  G AG PGLPGP G PG C+P+ C    AY ++    PG++KG
Sbjct: 1017 PGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQC----AYFASLAARPGNVKG 1072

Query: 689  P 689
            P
Sbjct: 1073 P 1073



 Score =  507 bits (1305), Expect = e-143
 Identities = 300/702 (42%), Positives = 357/702 (50%), Gaps = 84/702 (11%)

Query: 6   ASPRSLLVLLQVVVLALAQIRGPPGERGPPGPPGPPGVPGS---DGIDGDNGPPGKAGPP 62
           A  R+  +L       L Q+ G PGERG  G PG PG+ G     G+ G  G  G+AG P
Sbjct: 229 ADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLP 288

Query: 63  GPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGL-----PGPGF 117
           G  G PG  G  G  G+ G  GL G KG+ G  G  G  G PGLPG   L       PG 
Sbjct: 289 GAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGE 348

Query: 118 AGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTN 177
            GP G  G  GLPGE G++G  G+ GP GP+GPPG  G+ G  G   G  G+        
Sbjct: 349 QGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGA-PGAAGNPG------ 401

Query: 178 CPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYP 237
             PG  G PG  G  G  G  G+ G P   GK G +G+ GA+GE+G PGP GP+G  G P
Sbjct: 402 -APGHVGAPGPSGPPGSVGAPGLRGTP---GKDGERGEKGAAGEEGSPGPVGPRGDPGAP 457

Query: 238 GMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPK 297
           G+ GP G+ G  G  G+ G+ G  GP G +G RG PG  G  G  G PGI    G+ GP 
Sbjct: 458 GLPGPPGK-GKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGI----GVAGPP 512

Query: 298 GATGPPGINGKDGTPGTPGMKGSAGQAGQPG-----SPGHQGLAG-------VPGQPGTK 345
           G +GPPG  G  G+ G PG  G  G AG+ G     SPG   L          PG PG  
Sbjct: 513 GPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLP 572

Query: 346 GGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGER---GPVGQPGPQ 402
           G PG +G+ G  G PG  G  GK+GE GP G  GP GI G +G QGER   G VGQ G Q
Sbjct: 573 GLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQ 632

Query: 403 GRQGPKGEQGPPGIPGPQGLPGVKGD------KGSPGKTGPRGKVGDPGVAGLPGEKGEK 456
           G  G  G  GPPG PGP G  G+ G       +GSPGK GP G  G  G+ G+PGE+G++
Sbjct: 633 GHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKE 692

Query: 457 GESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGY---PGPPGPRGLAGNRGVPGQPGRQ 513
           G  G+PGP G+ G  GEPG PGP G  G PG +G+    G PGPRG +G  G+PGQ G  
Sbjct: 693 GRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLP 752

Query: 514 GVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPH 573
           G +G                                G  G  GP GP GPPG  G  G  
Sbjct: 753 GKDG------------------------------DTGPTGPQGPQGPRGPPGKNGSPGSP 782

Query: 574 GHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPG--- 630
           G PGP G PG  G+ G+ G+ G  G  G +G PGE   G  G+PG  G+PG PG PG   
Sbjct: 783 GEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGE--PGEKGVPGKEGVPGKPGEPGFKG 840

Query: 631 -QAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLG 671
            +   G  GD+G PG  G+ G PG+PG  G  G   P    G
Sbjct: 841 ERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPG 882



 Score =  316 bits (810), Expect = 4e-86
 Identities = 196/521 (37%), Positives = 240/521 (46%), Gaps = 77/521 (14%)

Query: 211 GPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGP------- 263
           GP+ D   + +QG  G  G       P    P+             A+G  GP       
Sbjct: 172 GPRTDPWENVDQGAQGACGRGNTSVLPSSVAPQCSMPKGTGHEFSAALGTQGPADQRADA 231

Query: 264 -----------PGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTP 312
                      PG +   G PG  GE G  G PG+RG     G +G  G PG  G+ G P
Sbjct: 232 RASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGE---IGEQGLAGRPGEKGEAGLP 288

Query: 313 GTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPG----FSGPPGK 368
           G PG  G  G+ G  G  G  GL   PG  G +G  G+ G  GP GLPG    F+  P  
Sbjct: 289 GAPGFPGVRGEKGDQGEKGELGL---PGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRM 345

Query: 369 EGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGD 428
            GE GP+GE G  G+ G+ G QG  G +G  GP G  G KG++G  G PG  G PG  G 
Sbjct: 346 PGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGH 405

Query: 429 KGSPGKTGPRGKVGDPGVAGLPGEKGEK------GESGEPGP------------------ 464
            G+PG +GP G VG PG+ G PG+ GE+      GE G PGP                  
Sbjct: 406 VGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGK 465

Query: 465 --KGQQGVRGEPGYPGP---SGDAGAPGVQGYP-----------------GPPGPRGLAG 502
              G+ G+RG PG PGP    GD GAPG+ G P                 GPPG +G  G
Sbjct: 466 GKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPG 525

Query: 503 NRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPG 562
           +RG+PG PG QG  GRD     +    + +L + +            G  G  G  G PG
Sbjct: 526 SRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPG 585

Query: 563 PPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGI 622
            PG  G +G  G  GP G+PG  G  G  G+ G +G  GE G  G+  +GHPG+PG  G 
Sbjct: 586 KPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGD--QGHPGVPGFMGP 643

Query: 623 PGLPGRPG-QAINGKDGDRGSPGAPGEAGRPGLPGPVGLPG 662
           PG PG PG   I G  G  G  G+PG+ G PG  GP GLPG
Sbjct: 644 PGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPG 684



 Score =  105 bits (262), Expect = 1e-22
 Identities = 68/179 (37%), Positives = 84/179 (46%), Gaps = 33/179 (18%)

Query: 9    RSLLVLLQVVVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEP 68
            R   +L Q+    +   +G PG  GPP               G +G PG+AGP G  G P
Sbjct: 926  RLAYLLAQMPPAYMKSSQGRPGPPGPP---------------GKDGLPGRAGPMGEPGRP 970

Query: 69   GKAGPDGPDGKPGIDGLTGAKGEPGP--MGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGP 126
            G+ G +GP G  G  G  GAKG+PG   +G+ G  G PG+PG PG PG    G PG PGP
Sbjct: 971  GQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGP 1030

Query: 127  VGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGP 185
                        +G+ GP G  G PGPPG PG+    Q     A F      P  +KGP
Sbjct: 1031 ------------QGETGPAGHPGLPGPPGPPGQCDPSQ----CAYFASLAARPGNVKGP 1073



 Score = 89.4 bits (220), Expect = 1e-17
 Identities = 61/149 (40%), Positives = 70/149 (46%), Gaps = 10/149 (6%)

Query: 550 GAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEV 609
           G  G  G PG PG  G  G+QG  G PG +G  G+ GA G  G  G KG +GEKG+ G  
Sbjct: 253 GERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLP 312

Query: 610 G----RGHPGMPGPPGIPGLPGR-----PGQAINGKDGDRGSPGAPGEAGRPGLPGPVGL 660
           G    RG  G  GP G PGLPG      P   + G+ G +G  G PG  G PGL G  G 
Sbjct: 313 GLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGE 372

Query: 661 PGFCEPAACLGASAYASARLTEPGSIKGP 689
            G   P    GA     A    PG+   P
Sbjct: 373 LGPQGPTGPPGAKGQEGAH-GAPGAAGNP 400



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 41/117 (35%), Positives = 50/117 (42%), Gaps = 16/117 (13%)

Query: 567 PGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLP 626
           PG +  +G PG RG  G+ G  G  G  G +G  G  G+ GE G     +PG PG PG+ 
Sbjct: 243 PGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAG-----LPGAPGFPGVR 297

Query: 627 GRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASARLTEP 683
           G           ++G  G  GE G PGL G  G  G   PA   G     S     P
Sbjct: 298 G-----------EKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHP 343



 Score = 37.4 bits (85), Expect = 0.047
 Identities = 40/141 (28%), Positives = 51/141 (36%), Gaps = 34/141 (24%)

Query: 543 SAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAV------------GQ 590
           SA RE+L    ++GP   P      G QG  G      +P  V                 
Sbjct: 162 SASRESLD---LLGPRTDPWENVDQGAQGACGRGNTSVLPSSVAPQCSMPKGTGHEFSAA 218

Query: 591 IGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAP---- 646
           +G  GP  +R +      +          PG+  L G PG+      G+ G PG P    
Sbjct: 219 LGTQGPADQRADARASCILAA-----KTAPGLKQLNGEPGER-----GEDGLPGKPGLRG 268

Query: 647 -----GEAGRPGLPGPVGLPG 662
                G AGRPG  G  GLPG
Sbjct: 269 EIGEQGLAGRPGEKGEAGLPG 289


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score =  571 bits (1471), Expect = e-163
 Identities = 325/716 (45%), Positives = 384/716 (53%), Gaps = 67/716 (9%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAG------PPGPKGEPGKAGPDGPDGK- 79
            G PG  GPPG  G PG+ G+ G DG+ G  G AG      P GP+G+PG  G  GP GK 
Sbjct: 925  GAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKG 984

Query: 80   -PGIDGLTGAKGEPGPMG--------------------IPGVKGQPGLPGPPGL---PGP 115
              G  GL G+ G PGP+G                    + G +G PG+PG PG    PG 
Sbjct: 985  KDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI 1044

Query: 116  GFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCP 175
            G AGPPGP GP G  G  G RG  G PGP GP+G  G PG PG  G   G  G +  L P
Sbjct: 1045 GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGP-PGKPGLSSLLSP 1103

Query: 176  -----------TNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGI 224
                        +CPPG  G PGL G K   G +G+ G PG +G  G KG+ G  G  G 
Sbjct: 1104 GDINLLAKDVCNDCPPGPPGLPGLPGFK---GDKGVPGKPGREGTEGKKGEAGPPGLPGP 1160

Query: 225  PGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGS 284
            PG  GPQG +G  G  G  G+ G  G+ G+ G +G  G PG  G  G  G AG  G +GS
Sbjct: 1161 PGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGS 1220

Query: 285  PGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVP---GQ 341
            PG  GP G  GP G  G PG  GK+G  G PG  G  G+AG+PG PG +G  G P   G 
Sbjct: 1221 PGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGH 1280

Query: 342  PGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGP 401
             G  G PG +GE G  GLPG  G PGK+G+ GP G  GPQG  G  G  G  G  G+PGP
Sbjct: 1281 TGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGP 1340

Query: 402  Q---GRQGPKGEQGPPGIP---GPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGE 455
                G++G KGE G PG+P   GP+G PG  G+KG PGK G  GK G+PG  G  G+ G 
Sbjct: 1341 SGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGI 1400

Query: 456  KGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGV 515
            KG+ G PG KGQ    G+PG PG  G  G  G QG PG  GP G  G  G PG PG +G 
Sbjct: 1401 KGDKGPPGGKGQP---GDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGE 1457

Query: 516  EGRDATDQHIVDVAL-KMLQEQLAEVAVSAKREAL-GAVGMMGPPGPPGPPGYPGKQGPH 573
                 T + ++   L K L+ +LA +        +  + G  GPPGPPG  G PG+ GP 
Sbjct: 1458 SPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPM 1517

Query: 574  GHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAI 633
            G PG  G  G+ G  G I   GPKG+RG KGDPG  G G  G  GPPGIPG PG PG A 
Sbjct: 1518 GEPGRPGQGGLEGPSGPI---GPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAK 1574

Query: 634  NGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASARLTEPGSIKGP 689
            +G  G  G  G  G AG PGLPGP G PG C+P+ C    AY ++    PG++KGP
Sbjct: 1575 DGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQC----AYFASLAARPGNVKGP 1626



 Score =  521 bits (1342), Expect = e-148
 Identities = 320/764 (41%), Positives = 367/764 (48%), Gaps = 148/764 (19%)

Query: 19   VLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKA---------GPPGPKGEPG 69
            +L L    GPPG  GPPGP G PG+PG  G  G  GPPG           GPPGP G  G
Sbjct: 709  LLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKG 768

Query: 70   KAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPG-PGFAGPPGPPGPVG 128
            + G  G DG PG  GL G  GE G  G PG KG+ GLPG PG PG  G  G  G  G +G
Sbjct: 769  EPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELG 828

Query: 129  LPGEIGIRGPKGDPGPDGPSGPP----------------------GPPGKPGRPGTIQGL 166
            LPG  G RG KG+ GP GP G P                      G PG PG PG +QG 
Sbjct: 829  LPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPG-LQGR 887

Query: 167  EGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPG 226
             G      PT  PPG KG  G  G  G AG  G    PGH G PGP G  G+ G  G+ G
Sbjct: 888  PGELGPQGPTG-PPGAKGQEGAHGAPGAAGNPGA---PGHVGAPGPSGPPGSVGAPGLRG 943

Query: 227  PPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPP-----GEEGPRGPPGRAGE--- 278
             PG  G RG  G AG +G  GP G +G  GA G  GPP     GE G RG PG  G    
Sbjct: 944  TPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGT 1003

Query: 279  --------------------KGDEGSPGIRGPQ--------GITGPKGATGPPGINGKDG 310
                                KGD G+PGI G          G+ GP G +GPPG  G  G
Sbjct: 1004 KAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPG 1063

Query: 311  T---PGTPGMKGSAGQAGQPGSPGHQGLAG------------------------VPGQPG 343
            +   PG PG +G AG+ G PG+PG +G  G                         PG PG
Sbjct: 1064 SRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPG 1123

Query: 344  TKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGER---GPVGQPG 400
              G PG +G+ G  G PG  G  GK+GE GP G  GP GI G +G QGER   G VGQ G
Sbjct: 1124 LPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKG 1183

Query: 401  PQGRQGPKGEQGPPGIPGPQGLPGVKGD------KGSPGKTGPRGKVGDPGVAGLPGEKG 454
             QG  G  G  GPPG PGP G  G+ G       +GSPGK GP G  G  G+ G+PGE+G
Sbjct: 1184 DQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEG 1243

Query: 455  EKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGY---PGPPGPRGLAGNRGVPGQPG 511
            ++G  G+PGP G+ G  GEPG PGP G  G PG +G+    G PGPRG +G  G+PGQ G
Sbjct: 1244 KEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEG 1303

Query: 512  RQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQG 571
              G +G                                G  G  GP GP GPPG  G  G
Sbjct: 1304 LPGKDG------------------------------DTGPTGPQGPQGPRGPPGKNGSPG 1333

Query: 572  PHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPG- 630
              G PGP G PG  G+ G+ G+ G  G  G +G PGE   G  G+PG  G+PG PG PG 
Sbjct: 1334 SPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGE--PGEKGVPGKEGVPGKPGEPGF 1391

Query: 631  ---QAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLG 671
               +   G  GD+G PG  G+ G PG+PG  G  G   P    G
Sbjct: 1392 KGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPG 1435



 Score =  501 bits (1291), Expect = e-142
 Identities = 309/771 (40%), Positives = 363/771 (47%), Gaps = 146/771 (18%)

Query: 25   IRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDG 84
            +RG PGE G PG PG  G+ G  G  G  GPPG+ G PG +GE G+ G  G  G+ G+DG
Sbjct: 549  MRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDG 608

Query: 85   LTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPV----GLPGEIGIRGPKG 140
              G  G+ G  G PG  G  G  G  G  GP  AGPPG PG V    GL GE G  GP+G
Sbjct: 609  FPGKPGDTGQQGRPGPSGVAGPQGEKGDVGP--AGPPGVPGSVVQQEGLKGEQGAPGPRG 666

Query: 141  D---PGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCP-----PGMKGPPGLQGVK 192
                PGP G  GP GP G+ G PG +QGL G    + P   P      G  GPPG+ G  
Sbjct: 667  HQGAPGPPGARGPIGPEGRDGPPG-LQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPP 725

Query: 193  GHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYK 252
            G  G  G+ G+ G  GKPGP G  G  G+ G  GPPGP G +G PG  G  G  G  G +
Sbjct: 726  GPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLR 785

Query: 253  GMVGAIGATGPPGEEGPRGPPGR------------AGEKGDEGSPGIRGPQGITGPKGAT 300
            G +G  G  G PGE+G  G PG              GEKG+ G PG++G +G  G  G  
Sbjct: 786  GEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPA 845

Query: 301  GPPGI----------------------NGKDGTPGTPGMKGSAGQ------AGQPGSPGH 332
            GPPG+                       G  G PG PG++G  G+       G PG+ G 
Sbjct: 846  GPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQ 905

Query: 333  QGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGE 392
            +G  G PG  G  G PG  G PGP G PG  G PG  G PG  GE G +G  G++G  G 
Sbjct: 906  EGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGP 965

Query: 393  RGPVGQPGPQGRQGP--KGEQGPPGIPGPQGLPG-----------------------VKG 427
             GP G PG  G  GP  KG+ G PG+ G  GLPG                       VKG
Sbjct: 966  VGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKG 1025

Query: 428  DKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPG 487
            D+G+PG  G  G  GDPG+    G  G  G SG PG KG  G RG PG+PGP G AG  G
Sbjct: 1026 DRGAPGIPGSPGSRGDPGI----GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDG 1081

Query: 488  VQGYPG------------------------------PPGPRGL------AGNRGVPGQPG 511
              G PG                              PPGP GL       G++GVPG+PG
Sbjct: 1082 APGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPG 1141

Query: 512  RQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQG 571
            R+G EG+        +     L            +   GA G +G  G  G PG PG  G
Sbjct: 1142 REGTEGKKG------EAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMG 1195

Query: 572  PHGHPGPRGV---------PGIVGAVGQIGNTGPKGKRGEKGDPGEVGR-GHPGMPGPPG 621
            P G+PGP G          PGI G+ G+ G  GP+G  G  G PGE G+ G  G PGPPG
Sbjct: 1196 PPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPG 1255

Query: 622  IPGLPGRPG----------QAINGKDGDRGSPGAPGEAGRPGLPGPVGLPG 662
             PG  G PG              G  GD G+PG  GE+G  GLPG  GLPG
Sbjct: 1256 EPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPG 1306



 Score =  497 bits (1280), Expect = e-140
 Identities = 303/724 (41%), Positives = 358/724 (49%), Gaps = 126/724 (17%)

Query: 28   PPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPK----------GEPGKAGPDGPD 77
            P GE+G  G  GP G+PG  G  G  GP G  GP G K          GE G+ G  G  
Sbjct: 479  PAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLP 538

Query: 78   GKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPG-PGFAGPPGPPGPVGLPGEIGIR 136
            G PG DG  G +GEPG +G PG+ G+ G+ GP G PG PG  G  G PG  G  GE G R
Sbjct: 539  GPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTR 598

Query: 137  GPKGDPGPDGPSGPPGPPGKPGRPGT--IQGLEGSADFLCPTNCPPGMKGPPGLQGVKGH 194
            G KG+ G DG  G PG  G+ GRPG   + G +G    + P   PPG+ G    Q  +G 
Sbjct: 599  GEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAG-PPGVPGSVVQQ--EGL 655

Query: 195  AGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGM 254
             G++G  G  GHQG PGP G  G  G +G  GPPG QG+R      G KG+ GP G  G+
Sbjct: 656  KGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLR------GKKGDMGPPGIPGL 709

Query: 255  VGAIGATGPPGEEGPRGP------------PGRAGEKGDEGSPGIRGPQGITGPKGATGP 302
            +G  G  GPPG  GP GP            PG+ G  G  G PG  GP G  GP G  G 
Sbjct: 710  LGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGE 769

Query: 303  PGINGKDGTPGTPGMKGSAGQ---AGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGL 359
            PG  G+DG PG PG++G  G+   AG+PG  G  GL G PG PG +G  GDQGE G  GL
Sbjct: 770  PGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGL 829

Query: 360  PGF------------SGPPG-------------KEGEPGPRGEIGPQGIMGQKGDQGERG 394
            PG             +GPPG               GE GP+GE G  G+ G+ G QG  G
Sbjct: 830  PGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPG 889

Query: 395  PVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLP---- 450
             +G  GP G  G KG++G  G PG  G PG  G  G+PG +GP G VG PG+ G P    
Sbjct: 890  ELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDG 949

Query: 451  --GEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDA--GAPGVQGYPGPPGPRG------- 499
              GEKG  GE G PGP G +G  G PG PGP G    G PG++G PG PGP G       
Sbjct: 950  ERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGK 1009

Query: 500  -------------LAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKR 546
                         + G+RG PG PG  G  G                             
Sbjct: 1010 VRGSENCALGGQCVKGDRGAPGIPGSPGSRG----------------------------D 1041

Query: 547  EALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKG-- 604
              +G  G  GP GPPG  G PG +G  G PGP+G  G  GA G  G  GP GK G     
Sbjct: 1042 PGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLL 1101

Query: 605  DPGEVGRGHPGM-----PGPPGIPGLPGRPG-QAINGKDGDRGSPGAPGEAGRPGLPGPV 658
             PG++      +     PGPPG+PGLPG  G + + GK G  G+ G  GEAG PGLPGP 
Sbjct: 1102 SPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPP 1161

Query: 659  GLPG 662
            G+ G
Sbjct: 1162 GIAG 1165



 Score =  435 bits (1118), Expect = e-122
 Identities = 268/641 (41%), Positives = 313/641 (48%), Gaps = 90/641 (14%)

Query: 31   ERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKG 90
            E  PP PP  P  PGS+ I G       + P G KGE G AGP                G
Sbjct: 450  EPPPPPPPQRPPTPGSEQI-GFLKTINCSCPAGEKGEMGVAGP---------------MG 493

Query: 91   EPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGP 150
             PGP G  G  G  G PGP G  G    GP G  G  G  G +G+ GP G  G  G  G 
Sbjct: 494  LPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQ-GEKGEKGSLGLPGPPGRDGSKGMRGE 552

Query: 151  PGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKP 210
            PG  G+PG PG +                 GM+GP G  G+ G  G+   +G PG QG+ 
Sbjct: 553  PGELGEPGLPGEV-----------------GMRGPQGPPGLPGPPGR---VGAPGLQGER 592

Query: 211  GPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPR 270
            G KG  G  GE+G+ G PG  G  G  G  GP G  GP G KG VG  G  G PG    +
Sbjct: 593  GEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQ 652

Query: 271  GPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSP 330
                  G KG++G+PG RG QG  GP GA GP G  G+DG PG  G++G  G  G PG P
Sbjct: 653  -----EGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIP 707

Query: 331  GHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQ 390
            G  GL G PG PG  G PG  G P   GLPG  G PGK G PGP             G  
Sbjct: 708  GLLGLQGPPGPPGVPGPPGPGGSP---GLPGEIGFPGKPGPPGP------------TGPP 752

Query: 391  GERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLP 450
            G+ GP G PGP G +G  GE+G  G+PG  GL G  G++G  G+ G +G+ G PG  G P
Sbjct: 753  GKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFP 812

Query: 451  GEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQG-------YPGPPGPRGLAGN 503
            G +GEKG+ GE G  G  G++G+ G  G +G AG PG+ G       +P  PG +G  G 
Sbjct: 813  GVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGE 872

Query: 504  RGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGP 563
            +G PG PG  G++GR                    E+         GA G  G  G PG 
Sbjct: 873  KGDPGLPGEPGLQGRP------------------GELGPQGPTGPPGAKGQEGAHGAPGA 914

Query: 564  PGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIP 623
             G PG  G  G PGP G PG VGA G  G  G  G+RGEKG  GE   G PG  GP G P
Sbjct: 915  AGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGE--EGSPGPVGPRGDP 972

Query: 624  GLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFC 664
            G PG PG    GKDG+      PG  G PGLPGP+G    C
Sbjct: 973  GAPGLPGPPGKGKDGE------PGLRGSPGLPGPLGTKAAC 1007



 Score =  326 bits (836), Expect = 4e-89
 Identities = 192/451 (42%), Positives = 223/451 (49%), Gaps = 67/451 (14%)

Query: 26   RGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGL 85
            +G PG  G  GPPG PG PG+DGI G  GPPG  G PG +G PG  GP G  G PG +G 
Sbjct: 1185 QGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGK 1244

Query: 86   TGAKGEPGPMGIPGVKGQPGLPGPPGLPGP----------GFAGPPGPPGPVGLPGEIGI 135
             G  G+PGP G PG  G+PGLPGP G  GP          G  GP G  G +GLPG+ G+
Sbjct: 1245 EGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGL 1304

Query: 136  RGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHA 195
             G  GD GP GP GP GP G PG+ G+                 PG  G PG  G  G  
Sbjct: 1305 PGKDGDTGPTGPQGPQGPRGPPGKNGS-----------------PGSPGEPGPSGTPGQK 1347

Query: 196  GKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMV 255
            G +G  G PG  G  GP+G  G  GE+G+   PG +G+ G PG  G KGE G  G KG  
Sbjct: 1348 GSKGENGSPGLPGFLGPRGPPGEPGEKGV---PGKEGVPGKPGEPGFKGERGDPGIKGDK 1404

Query: 256  GAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGT- 314
            G  G  G PG+ G  G  G  G  G +G PG  GP G  GP G  G PG+ G+  +  T 
Sbjct: 1405 GPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETL 1464

Query: 315  -------------------------PGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPG 349
                                       MK S G+ G PG PG  GL      PG  G  G
Sbjct: 1465 RRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGL------PGRAGPMG 1518

Query: 350  DQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKG 409
            + G PG  GL G SGP G +GE G +G+ G  G+    G +GE GP G PG  G  G   
Sbjct: 1519 EPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGV----GLRGEMGPPGIPGQPGEPG-YA 1573

Query: 410  EQGPPGIPGPQGLPGVKGDKGSPGKTGPRGK 440
            + G PGIPGPQG  G  G  G PG  GP G+
Sbjct: 1574 KDGLPGIPGPQGETGPAGHPGLPGPPGPPGQ 1604



 Score =  319 bits (818), Expect = 5e-87
 Identities = 199/474 (41%), Positives = 239/474 (50%), Gaps = 48/474 (10%)

Query: 230 PQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRG-PPGRAGEKGDEGSPGIR 288
           P G +G  G+AGP G  GP G  G +G +GA GP GE+G  G  P   GEKG++GS G+ 
Sbjct: 479 PAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLP 538

Query: 289 GPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGP 348
           GP G  G KG  G PG  G+ G PG  GM+G  G  G PG PG     G PG  G +G  
Sbjct: 539 GPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGR---VGAPGLQGERGEK 595

Query: 349 GDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQG----R 404
           G +GE G +GL GF   PGK G+ G +G  GP G+ G +G++G+ GP G PG  G    +
Sbjct: 596 GTRGEKGERGLDGF---PGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQ 652

Query: 405 QGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGP 464
           +G KGEQG PG  G QG PG  G +G     GP G+ G PG+ GL G+KG+ G  G PG 
Sbjct: 653 EGLKGEQGAPGPRGHQGAPGPPGARGP---IGPEGRDGPPGLQGLRGKKGDMGPPGIPGL 709

Query: 465 KGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQH 524
            G QG  G PG PGP G  G+PG+ G  G PG  G  G  G PG+ G  G  G   T   
Sbjct: 710 LGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGT--- 766

Query: 525 IVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGI 584
                                +   G  G  G PG PG  G  G+QG  G PG +G  G+
Sbjct: 767 ---------------------KGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGL 805

Query: 585 VGAVGQIGNTGPKGKRGEKGDPGEVG----RGHPGMPGPPGIPGLPGR-----PGQAING 635
            GA G  G  G KG +GEKG+ G  G    RG  G  GP G PGLPG      P   + G
Sbjct: 806 PGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPG 865

Query: 636 KDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASARLTEPGSIKGP 689
           + G +G  G PG  G PGL G  G  G   P    GA     A    PG+   P
Sbjct: 866 EQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAH-GAPGAAGNP 918



 Score =  267 bits (683), Expect = 2e-71
 Identities = 173/439 (39%), Positives = 207/439 (47%), Gaps = 42/439 (9%)

Query: 261 TGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGS 320
           T PP    P+ PP    E+      G       + P G  G  G+ G  G PG  G  G+
Sbjct: 449 TEPPPPPPPQRPPTPGSEQ-----IGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGA 503

Query: 321 AGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGE--- 377
            G  G PG  G +G  G+        GP  QGE G +G  G  GPPG++G  G RGE   
Sbjct: 504 IGPVGAPGPKGEKGDVGI--------GPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGE 555

Query: 378 IGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGP 437
           +G  G+ G+ G +G +GP G PGP GR G  G QG  G  G +G  G +G  G PGK G 
Sbjct: 556 LGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGD 615

Query: 438 RGKVGDPGVAGLPGEKGEKGESGEPGPKG-------QQGVRGEPGYPGPSGDAGAPGVQG 490
            G+ G PG +G+ G +GEKG+ G  GP G       Q+G++GE G PGP G  GAPG   
Sbjct: 616 TGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPG--- 672

Query: 491 YPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAV------SA 544
              PPG RG  G  G  G PG QG+ G+           L  LQ       V        
Sbjct: 673 ---PPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGG 729

Query: 545 KREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKG 604
                G +G  G PGPPGP G PGK GP+G PGP G  G  G  G+ G  G  G RGE G
Sbjct: 730 SPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIG 789

Query: 605 DPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFC 664
           + G  GR  PG  G  G+PG PG PG       G++G  G  GE G PGL G  G  G  
Sbjct: 790 EQGLAGR--PGEKGEAGLPGAPGFPGVR-----GEKGDQGEKGELGLPGLKGDRGEKGEA 842

Query: 665 EPAACLGASAYASARLTEP 683
            PA   G     S     P
Sbjct: 843 GPAGPPGLPGTTSLFTPHP 861



 Score =  111 bits (277), Expect = 3e-24
 Identities = 67/165 (40%), Positives = 81/165 (49%), Gaps = 30/165 (18%)

Query: 23   AQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGI 82
            A ++   G  GPPGPPG  G+            PG+AGP G  G PG+ G +GP G  G 
Sbjct: 1490 AYMKSSQGRPGPPGPPGKDGL------------PGRAGPMGEPGRPGQGGLEGPSGPIGP 1537

Query: 83   DGLTGAKGEPGP--MGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKG 140
             G  GAKG+PG   +G+ G  G PG+PG PG PG    G PG PGP            +G
Sbjct: 1538 KGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGP------------QG 1585

Query: 141  DPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGP 185
            + GP G  G PGPPG PG+    Q     A F      P  +KGP
Sbjct: 1586 ETGPAGHPGLPGPPGPPGQCDPSQ----CAYFASLAARPGNVKGP 1626



 Score = 34.7 bits (78), Expect = 0.30
 Identities = 28/88 (31%), Positives = 33/88 (37%), Gaps = 15/88 (17%)

Query: 617 PGPPGIPGLPGRPG-------QAIN--------GKDGDRGSPGAPGEAGRPGLPGPVGLP 661
           P PP  P  P  PG       + IN        G+ G  G  G PG  G  G  GPVG P
Sbjct: 451 PPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAP 510

Query: 662 GFCEPAACLGASAYASARLTEPGSIKGP 689
           G       +G   +      E GS+  P
Sbjct: 511 GPKGEKGDVGIGPFGQGEKGEKGSLGLP 538


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  555 bits (1429), Expect = e-158
 Identities = 318/685 (46%), Positives = 358/685 (52%), Gaps = 79/685 (11%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
            GP GERGP G  G PG  G+ G DG  GPPG+ GP GP+G  G  GP GP G PG DGL 
Sbjct: 916  GPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLP 975

Query: 87   GAKGEPGPMGIPGVKGQPGLPGPPGLPGP-------------GFAGPPGPPGPVGLPGEI 133
            G    PG  G  G +G+ G PGPPG+ GP             G  GPPGPPG  GLPG  
Sbjct: 976  G---HPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLA 1032

Query: 134  GIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNC-----PPGMKGPPGL 188
            G  G KGDPGP G  G  GPPG  G PG  +GL G    L          PPG  G PG 
Sbjct: 1033 GKEGTKGDPGPAGLPGKDGPPGLRGFPGD-RGLPGPVGALGLKGNEGPPGPPGPAGSPGE 1091

Query: 189  QGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGP------------PGPQGIRGY 236
            +G  G AG  GI G PG QG PGP G+ GA GE+G  GP            PGP G  G 
Sbjct: 1092 RGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGP 1151

Query: 237  PGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGI--- 293
            PG  G KGE G  G KG  G  G  GPPG  GP+GP G+ G  G +G PG RG QG+   
Sbjct: 1152 PGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQ 1211

Query: 294  ---TGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQ---PGSPGHQGLAGVPGQPGTKGG 347
                GP+G  GPPG  G  G PG PG KG  G  GQ   PG PG +G +G PG  G +G 
Sbjct: 1212 KGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGP 1271

Query: 348  PGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGP 407
            PG  G PG  G     G PG+ GEPG  GE GP G  G++G++GE GP G  GP G +GP
Sbjct: 1272 PGGIGNPGAVGE---KGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGP 1328

Query: 408  KGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQ 467
             G+ GP G PGP G PG  G  G PG  G  G  GD G  G PG+ G  G +GEPGP G 
Sbjct: 1329 PGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGP 1388

Query: 468  QGVRGEPGYPGPSG---DAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQH 524
             G RG PG  GP G   + GA G  G  GPPG  G  G +G PG+PG  G+ G       
Sbjct: 1389 PGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRG------- 1441

Query: 525  IVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGI 584
                    +   + E  +       G+ G  GPPGP GPPG PG +G  G  G +G PG+
Sbjct: 1442 --------IPGPVGEQGLP------GSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGL 1487

Query: 585  VGAVGQIGNTGPKGKRGEKGDPGEVG-------RGHPGMPGPPGIPGLPGRPGQAINGKD 637
            +G +G  G  G KG RG  G  G  G        G  G  GPPG PGLPG PG    G  
Sbjct: 1488 IGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGP--KGAK 1545

Query: 638  GDRGSPGAPGEAGRPGLPGPVGLPG 662
            G  G  G  GEAG PG PGP G PG
Sbjct: 1546 GSSGPTGPKGEAGHPGPPGPPGPPG 1570



 Score =  541 bits (1395), Expect = e-154
 Identities = 325/768 (42%), Positives = 374/768 (48%), Gaps = 127/768 (16%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
            GP G  GP GPPGPPG PG  G+DG  GP G  GP G  G PG+ G  G  G PG  G  
Sbjct: 679  GPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAI 738

Query: 87   GAKGEPGPMGIPGVKGQPGLPGPPGLPGP-------GFAGPPGPPGPVGLPGEIGIRGPK 139
            G  GE GP+G PG+ G PG  GPPG PG        G  GPPGP GP+G PG  G++G  
Sbjct: 739  GPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGAD 798

Query: 140  GDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNC--------PPGMKGP---PGL 188
            G  G  G  G  G  G PG  G + G++G    + P           P G  GP   PG 
Sbjct: 799  GIRGLKGTKGEKGEDGFPGFKGDM-GIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGP 857

Query: 189  QGVKGHAGKRGILGDPGHQGKPGPKGDVG------ASGEQGIPGPPGPQGIRGYPGMAGP 242
             G  G  GK G+ G PG+ G+ GPKG +G      A+GE+G  G PG  G RG  G  GP
Sbjct: 858  LGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGP 917

Query: 243  KGETGPHGY------KGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGP 296
            +GE GP G       KG  G  G  GPPGE GP GP G  G  G +G PG  G  G+ G 
Sbjct: 918  RGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGH 977

Query: 297  KGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPG------D 350
             G  G  G  GK G PG PG+ G  G  G+ G  G +G  G PG PG +G PG       
Sbjct: 978  PGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGT 1037

Query: 351  QGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGE 410
            +G+PGP GLPG  GPPG  G PG RG  GP G +G KG++G  GP G  G  G +GP G 
Sbjct: 1038 KGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGA 1097

Query: 411  QGP---PGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGV------------AGLPGEKGE 455
             GP   PG PGPQG PG  G+KG+PG+ GP+G  G  G+             G PGE G+
Sbjct: 1098 AGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGD 1157

Query: 456  KGESGEPGPKGQQGVRGEPGYPGPSGDAGA---PGVQGYPGPPGPRGLAG---------N 503
            KGE GEPG KG +G +GE G PGP+G  G    PG  G  G PGPRG  G          
Sbjct: 1158 KGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGP 1217

Query: 504  RGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGP 563
            RG PG PG  G++G                           ++   G VG MGPPGPPGP
Sbjct: 1218 RGFPGPPGPVGLQGLPGPP---------------------GEKGETGDVGQMGPPGPPGP 1256

Query: 564  ---PGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTG------------PKGKRGEKGDPGE 608
                G PG  GP G PG  G PG VG  G+ G  G            PKG+RGEKG+ G 
Sbjct: 1257 RGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGP 1316

Query: 609  VGRGHP-------------GMPGPPGIPGLPGRPGQ----------AINGKDGDRGSPGA 645
             G   P             G PGP G PG PG PG+             G DG+ G  G+
Sbjct: 1317 SGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGS 1376

Query: 646  PGEAGRPGLPGPVGLPGFCEPAACLG----ASAYASARLTEPGSIKGP 689
            PG  G PG  GP G  G   PA   G      A   A L  P    GP
Sbjct: 1377 PGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGP 1424



 Score =  528 bits (1360), Expect = e-150
 Identities = 329/763 (43%), Positives = 377/763 (49%), Gaps = 122/763 (15%)

Query: 14   LLQVVVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGD---NGPPGKAGPPGPKGEPGK 70
            +LQ   LAL    GP G  G PGP GPPG  G  G  GD    GP G  GPPGP G+PG+
Sbjct: 549  ILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGR 608

Query: 71   AGPDGPDGKPGIDGLTGAKGE---PGPMGIPGVKGQPGLPGPPGLPGP------------ 115
             G  G DG  G+ G TG KG+    G  G+PG KG  G PGP G PGP            
Sbjct: 609  RGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGE 668

Query: 116  -------------GFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGT 162
                         G  GP GPPGP G PG  G+ G  G  G  GP G PGPPG+ G PG 
Sbjct: 669  VGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGA 728

Query: 163  IQGLEGSADFLCPTN-----CPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVG 217
             QGL G    + P         PG+ G PG  G  GH GK G  G+ G QG PGP+G +G
Sbjct: 729  -QGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIG 787

Query: 218  ASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMV------GAIGATGPPGEEGPRG 271
              G +G+    G  GIRG  G  G KGE G  G+KG +      G IG  GP GE+GP G
Sbjct: 788  YPGPRGV---KGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEG 844

Query: 272  PPGRA------------GEKGDEGSPGIRGPQGITGPKGATGPPGI---NGKDGTPGTPG 316
            P GR             GEKG  G PG+ G  G  GPKG+ G PG    NG+ G  GTPG
Sbjct: 845  PKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPG 904

Query: 317  MKGSAGQAGQPGSPGHQGLAGVPGQPGTKGG---------PGDQGEPGPQGLPGF----- 362
              G  GQ G  G  G +G  G+ G+PG KG          PG++G  GPQG  GF     
Sbjct: 905  KPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKG 964

Query: 363  -SGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQ---GPPGIPG 418
              GPPGK+G PG  G+ G  G  G+ G  G  G VG  GP G  GP GE+   GPPG PG
Sbjct: 965  PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPG 1024

Query: 419  PQGLPGVKGDKGS---------PGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQG 469
             QGLPG+ G +G+         PGK GP G  G PG  GLPG  G  G  G  GP G  G
Sbjct: 1025 EQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPG 1084

Query: 470  VRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHI---- 525
              G PG  GP+G AG  G+ G PGP GP G AG +G PG+ G QG  GRD     +    
Sbjct: 1085 PAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPG 1144

Query: 526  --VDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGP---------PGPPGYPGKQGPHG 574
                V          E+    ++ + G  G  GPPGP         PGP G  G+ GP G
Sbjct: 1145 PAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRG 1204

Query: 575  H---------PGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGL 625
                       GPRG PG  G VG  G  GP G++GE GD G++  G PG PGP G  G 
Sbjct: 1205 QQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQM--GPPGPPGPRGPSGA 1262

Query: 626  PGRPGQAINGKDGDRGSPGA------PGEAGRPGLPGPVGLPG 662
            PG  G    G  G  G+PGA      PGEAG PGLPG  G PG
Sbjct: 1263 PGADGP--QGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPG 1303



 Score =  506 bits (1303), Expect = e-143
 Identities = 312/762 (40%), Positives = 356/762 (46%), Gaps = 137/762 (17%)

Query: 23   AQIRGPPGERGPP---------GPPGPPGVPGSDGIDGD--------------------- 52
            A + GPPG  GP          GPPG PG+PG+DG+ G                      
Sbjct: 477  AGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKG 536

Query: 53   ------------------------------NGPPGKAGPPGP---KGEPGKAGPDGPDGK 79
                                           G PG  GPPG    KGEPG  GP GP G 
Sbjct: 537  PMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGV 596

Query: 80   PGIDGLTGAKGEPGPMGIPGVKGQPGLPGP---------PGLPG-------PGFAGPPGP 123
             G  G  G  G  G  G  G +G PG  GP          GLPG       PG +GPPGP
Sbjct: 597  QGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGP 656

Query: 124  PGPVGL---PGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPP 180
            PG  G     GE+G RG  G+PGP G  GP GPPG PG PG + G++G          P 
Sbjct: 657  PGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPG-VTGMDGQPG-------PK 708

Query: 181  GMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMA 240
            G  GP G  G  G  G  G  G PG QG  GP G+ G  G+ G+PG PG  G  G+PG  
Sbjct: 709  GNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKE 768

Query: 241  GPKGETGPHGYKGMVGAIGATGP---PGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPK 297
            GP GE G  G  G  G IG  GP    G +G RG  G  GEKG++G PG +G  GI G +
Sbjct: 769  GPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDR 828

Query: 298  GATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGG---------- 347
            G  GPPG  G+DG  G  G  G  G  G  G PG +G  GVPG PG  G           
Sbjct: 829  GEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFP 888

Query: 348  --PGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQ 405
              PG  GE G +G PG  GP G+ G  GPRGE GP+GI G+ G +G  G  G  GP G +
Sbjct: 889  GFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGER 948

Query: 406  GPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPK 465
            GP G QGP G PGP+G PG  G  G PG  G RG+ G  G  G PG  G  G  G  G  
Sbjct: 949  GPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGET 1008

Query: 466  GQQGVRGEPGYPGPSGDAGAPGV---QGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATD 522
            G  G RG PG PGP G+ G PG+   +G  G PGP GL G  G PG  G  G  G     
Sbjct: 1009 GPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRG----- 1063

Query: 523  QHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVP 582
                               +     ALG  G  GPPGPPGP G PG++GP G  GP G+P
Sbjct: 1064 -------------------LPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIP 1104

Query: 583  GIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGS 642
            G  G  G  G  G KG  GEKG  G  GR   G+ GP G+PG  G  G    G+DGD+G 
Sbjct: 1105 GRPGPQGPPGPAGEKGAPGEKGPQGPAGR--DGLQGPVGLPGPAGPVGPP--GEDGDKGE 1160

Query: 643  PGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASARLTEPG 684
             G PG+ G  G  G  G PG   P   +G    + A   EPG
Sbjct: 1161 IGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGAD-GEPG 1201



 Score =  503 bits (1295), Expect = e-142
 Identities = 316/737 (42%), Positives = 368/737 (49%), Gaps = 93/737 (12%)

Query: 25   IRGPPGERGPPGPPG--PPGV-----PGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPD 77
            I GP GE+G  G P    PG+     PG +G  G  GPPG  GP G  G+PG+ GP G  
Sbjct: 445  IGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRP 504

Query: 78   GKPGIDGLTGAKGEPGPM-GIP---GVKGQPGLPGPP-----------------GLPGP- 115
            G PG DGL    G PG M  +P   G  G  G  GP                   L GP 
Sbjct: 505  GLPGADGLP---GPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPA 561

Query: 116  GFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGP---SGPPGPPGKPGRPGTIQGLEGSADF 172
            G  G  G PGPVG PG  G++G  GD GP GP    GPPGP GKPGR G   G +G+   
Sbjct: 562  GPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRA-GSDGARGM 620

Query: 173  LCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQG 232
               T    G KG  G  G+ G  G++G  GDPG  G PGP GD G  G+ G  GP G  G
Sbjct: 621  PGQT----GPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPG 676

Query: 233  IRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQG 292
              G  G+ GPKG  GP G  G+ G  G  GP G  GP+G PG  G++G+ G+ G+ GPQG
Sbjct: 677  EPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQG 736

Query: 293  ITGPKGATGP------PGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKG 346
              GP G  GP      PG+ G DG PG PG +G  G+ G  G PG QG  G PG  G KG
Sbjct: 737  AIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKG 796

Query: 347  G------PGDQGEPGPQGLPGFSGPPGKEGE------PGPRGEIGPQGIMGQKGDQGERG 394
                    G +GE G  G PGF G  G +G+      PGPRGE GP+G  G+ G  G+ G
Sbjct: 797  ADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPG 856

Query: 395  PVGQPGPQ------------GRQGPKGEQGPPGIPGP------QGLPGVKGDKGSPGKTG 436
            P+G PG +            GRQGPKG  G PG PG       +G PG  G +G  G TG
Sbjct: 857  PLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTG 916

Query: 437  PRGKVGDPGVAGLPGEKGEK---GESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPG 493
            PRG+ G  G+ G PG KG     G +G PG +G  G +G  G+PGP G  G PG  G PG
Sbjct: 917  PRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPG 976

Query: 494  PPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVG 553
             PG RG  G +G  G PG  GV G          +  +             ++   G  G
Sbjct: 977  HPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGER---GHPGPPGPPGEQGLPGLAG 1033

Query: 554  MMGPPGPPGPPGYPGKQGP---HGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG 610
              G  G PGP G PGK GP    G PG RG+PG VGA+G  GN GP G  G  G PGE  
Sbjct: 1034 KEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGE-- 1091

Query: 611  RGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSP---GAPGEAGRPGLPGPVGLPGFCEPA 667
            RG  G  GP GIPG PG  G    G  G++G+P   G  G AGR GL GPVGLPG   P 
Sbjct: 1092 RGPAGAAGPIGIPGRPGPQGPP--GPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPV 1149

Query: 668  ACLGASAYASARLTEPG 684
               G        + EPG
Sbjct: 1150 GPPGEDG-DKGEIGEPG 1165



 Score =  469 bits (1207), Expect = e-132
 Identities = 293/719 (40%), Positives = 345/719 (47%), Gaps = 120/719 (16%)

Query: 38   PGPPGVPGSDGIDGD-------NGPPGKAGPP-GPKGEPGKAGPDGPDGKPGIDGLTGAK 89
            P PP   G+D ++G+       N       P   P   P + GP  P  +  I       
Sbjct: 389  PAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDPTSSPSEIGPGMPANQDTIYE----- 443

Query: 90   GEPGPMGIPGVKGQPGLPGPPGLPGPG--FAGPPGPPGPVGLPGEIGIRGPKGDPGPDGP 147
                  GI G +G+ G  G P +  PG    GPPGP GP GLPG  G  GP G  G  G 
Sbjct: 444  ------GIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGE 497

Query: 148  SGPPGPPGKPGRPGTIQGLEGS---ADFLCPTNCPPGMKGP------------------- 185
             GPPG PG PG  G + G  G+     F        G KGP                   
Sbjct: 498  RGPPGRPGLPGADG-LPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLA 556

Query: 186  -PGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGP------------QG 232
              G  G  G  G+ G +G PG  G  G  GDVG  G +G+ GPPGP             G
Sbjct: 557  LRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDG 616

Query: 233  IRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGS------PG 286
             RG PG  GPKG+ G  G  G+ G  G  G PG  GP GPPG  GE+GD+G       PG
Sbjct: 617  ARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPG 676

Query: 287  IRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKG 346
              GP+G+ GPKG  GPPG  G  G  G PG KG+ G  G+PG PG QG  G  G PG +G
Sbjct: 677  EPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQG 736

Query: 347  GPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGP----- 401
              G  GE GP G PG  G PG +G PG  G+ GP G  G +G  G +GP+G PGP     
Sbjct: 737  AIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKG 796

Query: 402  ----QGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGK------------VGDPG 445
                +G +G KGE+G  G PG +G  G+KGD+G  G  GPRG+             GDPG
Sbjct: 797  ADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPG 856

Query: 446  VAGLPGEKGEKGESGEPGPKGQQGVRGE---PGYPGPSGDAGA------PGVQGYPGPPG 496
              G PGEKG+ G  G PG  G+QG +G    PG+PG +G+ G       PG +G  GP G
Sbjct: 857  PLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTG 916

Query: 497  PRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMG 556
            PRG  G RG+ G+PG +G  G D                         +R   G  G  G
Sbjct: 917  PRGERGPRGITGKPGPKGNSGGD------------------GPAGPPGERGPNGPQGPTG 958

Query: 557  PPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-RGHPG 615
             PGP GPPG PGK G  GHPG RG  G  G  G  G  G  G +G  G+ G +G RGHPG
Sbjct: 959  FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPG 1018

Query: 616  MPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGL---PGPVGLPGFCEPAACLG 671
             PGPPG  GLPG  G+   G  GD G  G PG+ G PGL   PG  GLPG   P   LG
Sbjct: 1019 PPGPPGEQGLPGLAGK--EGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPG---PVGALG 1072



 Score =  429 bits (1104), Expect = e-120
 Identities = 269/635 (42%), Positives = 299/635 (47%), Gaps = 167/635 (26%)

Query: 27   GPPGERGP---------PGPPGPPGVPGSDGIDGDNG---------------PPGKAGPP 62
            GPPGERGP         PGP GPPG PG DG+ G  G               PPG  GP 
Sbjct: 943  GPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQ 1002

Query: 63   GPKGE---------PGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGL---PGPP 110
            GP GE         PG  GP G  G PG+ G  G KG+PGP G+PG  G PGL   PG  
Sbjct: 1003 GPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDR 1062

Query: 111  GLPGP-------GFAGPPGPPGPVGLPGE---IGIRGPKGDPGPDGPSGPPGPPGKPGRP 160
            GLPGP       G  GPPGPPGP G PGE    G  GP G PG  GP GPPGP G+ G P
Sbjct: 1063 GLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAP 1122

Query: 161  GTI--QGLEGSADFLCPTNCP--PGMKGPPGLQGVKGHAGK---RGILGDPGHQGKPGPK 213
            G    QG  G      P   P   G  GPPG  G KG  G+   +G  GD G QG PGP 
Sbjct: 1123 GEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPT 1182

Query: 214  GDVGASGE---------------------------QGIPGPPGPQGIRGYPGMAGPKGET 246
            G  G  G+                           +G PGPPGP G++G PG  G KGET
Sbjct: 1183 GPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGET 1242

Query: 247  GPHGYKGMVGAIGATGP---PGEEGPRGPPG---------RAGEKGDEGSPGI------- 287
            G  G  G  G  G  GP   PG +GP+GPPG           GE G+ G PG+       
Sbjct: 1243 GDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPP 1302

Query: 288  -----RGPQGITGPKGATGPPGINGK---DGTPGTPGMKGSAGQAGQPGSPGHQGLAGVP 339
                 RG +G +GP GA GPPG  G    DG  G+PG  G  G  G PG PG  G  G P
Sbjct: 1303 GPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPP 1362

Query: 340  GQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQP 399
            G  G  G PG  G PGP G PG SGPPGK G PGP G  G QG  G KG+ G  GP G+ 
Sbjct: 1363 GDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKT 1422

Query: 400  GPQGRQG---------------PKGEQGPPGIPGPQGLPGVKGDKGSPG---KTGPRGKV 441
            GP G QG               P GEQG PG PGP G PG  G  G PG    +GP+G+ 
Sbjct: 1423 GPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEK 1482

Query: 442  GDPGVAGL---PGEKGEKGESGEPGP------KGQQGV---------------------- 470
            G PG+ GL   PGE+GEKG+ G PGP      KG+QG+                      
Sbjct: 1483 GHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPK 1542

Query: 471  -----------RGEPGYPGPSGDAGAPGVQGYPGP 494
                       +GE G+PGP G  G PG    P P
Sbjct: 1543 GAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLP 1577



 Score =  325 bits (834), Expect = 7e-89
 Identities = 227/643 (35%), Positives = 283/643 (44%), Gaps = 133/643 (20%)

Query: 139 KGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTN-CPPGMKGPPGLQGVKGHAGK 197
           +G+  PD P+ P      P           +AD    +N  PP  +G   L+G       
Sbjct: 359 EGEENPDQPTDPGAGAEIP---------TSTADTSNSSNPAPPPGEGADDLEGEFTEETI 409

Query: 198 RGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGE------------ 245
           R +      +    P  D  +S  +  PG P  Q    Y G+ GP+GE            
Sbjct: 410 RNL-----DENYYDPYYDPTSSPSEIGPGMPANQDTI-YEGIGGPRGEKGQKGEPAIIEP 463

Query: 246 ----------TGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSP---------- 285
                      GP G  G  G +G TG  G+ G RGPPGR G  G +G P          
Sbjct: 464 GMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLP 523

Query: 286 -----------------------------------GIRGPQGITGPKGATGPPGINGKDG 310
                                              G  GP G+TG  G  GPPG  G  G
Sbjct: 524 FRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKG 583

Query: 311 TPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKE- 369
            PG  G +G  G  G PG  G  G  G  G  G +G PG  G  G +G  G +G PG++ 
Sbjct: 584 EPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKG 643

Query: 370 --GEPGPRGEIGPQGIMGQKGDQGERGP---VGQPGPQGRQGPKGEQGPPGIPGPQGL-- 422
             G+PGP G  GP G  G++GD GE GP    G+PGP+G  GPKG  GPPG PG  G+  
Sbjct: 644 HRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDG 703

Query: 423 -PGVKGDKGSPGKTGPRGKVGDPGVAGLPGEK------GEKGESGEPGPKGQQGVRGEPG 475
            PG KG+ G  G+ GP G+ G+PG  GLPG +      GEKG  G+PG  G  G  G PG
Sbjct: 704 QPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPG 763

Query: 476 YPGPSGDAGAPGVQGYPGP------PGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVA 529
           +PG  G  G  G QG PGP      PGPRG+ G  G+ G  G +G +G D       D+ 
Sbjct: 764 HPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMG 823

Query: 530 LKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGP---------------PGYPGKQGP-- 572
           +K  + ++       +    G  G  GP G PGP               PGYPG+QGP  
Sbjct: 824 IKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKG 883

Query: 573 ----------HGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-RGHPGMPGPPG 621
                     +G  G RG PG  G  GQ G TGP+G+RG +G  G+ G +G+ G  GP G
Sbjct: 884 SIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAG 943

Query: 622 IPGLPGRPG-QAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGF 663
            PG  G  G Q   G  G +G PG PG+ G PG PG  G  GF
Sbjct: 944 PPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGF 986



 Score =  296 bits (759), Expect = 3e-80
 Identities = 171/362 (47%), Positives = 192/362 (53%), Gaps = 36/362 (9%)

Query: 20   LALAQIRGPPGER---------GPPGPPGPPGVPGSDGIDGDNGPPGKAGPP---GPKGE 67
            + L  + GPPGE+         GPPGPPGP G  G+ G DG  GPPG  G P   G KGE
Sbjct: 1227 VGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGE 1286

Query: 68   PGKAGP---DGPDGKPGIDGLTGAKGEPGPMGI---PGVKGQPGLPGPPGLPGP-GFAGP 120
            PG+AG     G  G PG  G  G KGE GP G    PG KG PG  GP G PGP GF G 
Sbjct: 1287 PGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGD 1346

Query: 121  PGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPP 180
            PGPPG  G  G+ G  G KGD G  G +G PGP G+PG P    G  G          PP
Sbjct: 1347 PGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPG-PSGPPGKRG----------PP 1395

Query: 181  GMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMA 240
            G  GP G QG KG  G+ G+ G PG  G  GP+G  G  G  G+ G PGP G +G PG  
Sbjct: 1396 GPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSP 1455

Query: 241  GPKGETGPHGYKGMVGAIGATGPPGEEGPR------GPPGRAGEKGDEGSPGIRGPQGIT 294
            GP G  GP G  G+ G  G +GP GE+G        GPPG  GEKGD G PG +G  G  
Sbjct: 1456 GPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPK 1515

Query: 295  GPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEP 354
            G +G TGP G  G  G PG PG  G  G  G  G  G +G AG PG PG  G PG+  +P
Sbjct: 1516 GEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQP 1575

Query: 355  GP 356
             P
Sbjct: 1576 LP 1577


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  548 bits (1413), Expect = e-156
 Identities = 330/775 (42%), Positives = 381/775 (49%), Gaps = 144/775 (18%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKA--GPDGPDGKPGIDG 84
            GPPG +G PG PGPPG PG+ G  G  GPPG  G PGPKGEPG A  GP GP G PG  G
Sbjct: 710  GPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG 769

Query: 85   LTGAKGE------------------PGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPG- 125
              G KG+                  PGP G  G  GQPG  GPPGLPG G  GPPGPPG 
Sbjct: 770  ALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI 829

Query: 126  --PVGLPGEIGIRGPKGDPGPDG--------------------PSGPPGPPGKPGRPGT- 162
              P+G PG  GI G KGDPGP G                    P GPPG PG PG+ G  
Sbjct: 830  PGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889

Query: 163  -IQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGE 221
               G +G    + P   PPG  G PG  GV G  G  G+ G PG    PGP G+ G+ GE
Sbjct: 890  GFPGTKGEMGMMGPPG-PPGPLGIPGRSGVPGLKGDDGLQGQPG---LPGPTGEKGSKGE 945

Query: 222  QGIPGPPGP--------QGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPP 273
             G+PGPPGP        +G +G PG+ G  G +GP GY+G+ G  G  G  G+ G  GPP
Sbjct: 946  PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPP 1005

Query: 274  GRAGEKGDEGSPGIRGPQGITG---------PKGATGPPGINGKDGTPGTPGMKGSAGQA 324
            G  G  G  G PG+ GP G+ G         P+G  GPPG +G  G PG+PG+ G  G  
Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065

Query: 325  GQPG-----------------------------SPGHQGLAGVPGQPGTKGGPG---DQG 352
            G PG                             S G  GL G+PG PG KG PG     G
Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG 1125

Query: 353  EPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQG 412
             PGP G  G SGPPG  G PG  G +G  G  GQ G  GE+G  GQ G  G  G KGE G
Sbjct: 1126 TPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG 1185

Query: 413  PPGI--PGPQGLPGVKGDKGS------PGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGP 464
             PG   PGP GLPG+ G KG       PG  G  G  G+PG  G PG +G  G  G PGP
Sbjct: 1186 QPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP 1245

Query: 465  -----KGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRD 519
                 KG  G +G PG PGP+G  G PG +G PG PG  G+ G +G PGQPG  G+ G  
Sbjct: 1246 ALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPG-- 1303

Query: 520  ATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPG-- 577
                         L+       +       G  GM G PG PG PG+PG +GP G PG  
Sbjct: 1304 -------------LKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSA 1350

Query: 578  -PRGVPGIVGAVGQIGNTGPKGK----RGEKGDPGEVGR----------GHPGMPGPPGI 622
             P G PG++G  G  G  GP G+    +G+ G PG  G+          G  G+PGP G 
Sbjct: 1351 GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGP 1410

Query: 623  PGLPGRPG-QAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYA 676
            PG PGR G    +G  G +G PG PG+ G  GL GP G  G   P    G S+ A
Sbjct: 1411 PGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1465



 Score =  521 bits (1342), Expect = e-148
 Identities = 333/778 (42%), Positives = 387/778 (49%), Gaps = 142/778 (18%)

Query: 27   GPPGERGPPGPPG--PPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKA------------- 71
            G PG  GP GPPG  PPG  G  GI G  G PG+ G PGPKG+PG+              
Sbjct: 612  GLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNP 671

Query: 72   ---------GPDGPDGKPGIDGLTGAKGEPGPMGI-----PGVKGQPGLPGPPGLPG--- 114
                     G  G  G+PG+ G+ G+KGEPG  GI     PG KG PG+PGPPG PG   
Sbjct: 672  GRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPG 731

Query: 115  ----------PGFAGP--------PGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGK 156
                      PGF GP        PGPPGP GLPG  G  GPKGD G  GP GPPG  G 
Sbjct: 732  RIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGL 791

Query: 157  PGRPGTIQ--GLEGSADFLCPTNCPP-GMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPK 213
             G PG     G  G    + P   P  G++GPPG  G+ G  G+ G+ G PG +G PGP 
Sbjct: 792  DGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPP 851

Query: 214  G-DV-GASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRG 271
            G DV G  GE+G PG PG  G  G PG  G  G+ G  G+ G  G +G  GPPG  GP G
Sbjct: 852  GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLG 911

Query: 272  PPGRAGEKGDEGSPGIRGPQGITGP---KGATGPPGINGKDGTPGTPGMKGSAGQAGQPG 328
             PGR+G  G +G  G++G  G+ GP   KG+ G PG+ G  G P  P + GS G+ G+PG
Sbjct: 912  IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG-PMDPNLLGSKGEKGEPG 970

Query: 329  SPG---------HQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIG 379
             PG         +QGL G PGQPG  G PG  G PGP+G PG  G PG  G PG +G IG
Sbjct: 971  LPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIG 1030

Query: 380  PQGIMGQKGDQGERGPVG---QPGPQGRQGPKGEQGPPGIP--GPQGLPGVKGDKGSPG- 433
              G  G +G +G  GP G   QPG  G  G KG++G PGI   G  GLPG KG+ G PG 
Sbjct: 1031 DMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGY 1090

Query: 434  --KTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGY 491
                G +G VGDPG+ GLPG  G KG+ G PG        G PG PGP G +G PG  G 
Sbjct: 1091 PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPG------FPGTPGPPGPKGISGPPGNPGL 1144

Query: 492  PGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGA 551
            PG PGP G  G+ G PG PG +G  G+D                       + ++   G 
Sbjct: 1145 PGEPGPVGGGGHPGQPGPPGEKGKPGQDGIP------------------GPAGQKGEPGQ 1186

Query: 552  VGMMGPPGPPGPPGY---------------PGKQGPHGHPGPRGVPGIVGAVGQIGN--- 593
             G  G PGPPG PG                PG  GP G PG  G PG+ G  G  G+   
Sbjct: 1187 PGF-GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP 1245

Query: 594  --TGPKGKRGEKGDPGEVG-RGHPGMPGPPGIPGLP---------GRPGQ----AINGKD 637
               GPKG  G +G PG  G  G  G+PGP G PGLP         G PGQ     + G  
Sbjct: 1246 ALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLK 1305

Query: 638  GDRGSPGAPGEAGRPGL------PGPVGLPGFCEPAACLGASAYASARLTEPGSIKGP 689
            GD+G PG  G  GRPGL      PG  G+PGF       G    A     EPG I  P
Sbjct: 1306 GDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPE-GEPGLIGPP 1362



 Score =  509 bits (1312), Expect = e-144
 Identities = 336/807 (41%), Positives = 377/807 (46%), Gaps = 184/807 (22%)

Query: 27   GPPGERGP----------PGPPGPPGVPGSDGIDGDNG---------------------- 54
            GPPG  GP          PGPPGPPG PG  G+ G+ G                      
Sbjct: 435  GPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPG 494

Query: 55   ---------PPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMG-------IP 98
                     PPG  G PG KGE G+AG  GP G PGI G  GA G PG  G        P
Sbjct: 495  QPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFP 554

Query: 99   GVKGQ------PGLPGPPGLPG-PGFAGPPGPPGPVGLPGEI---GIRGPKGDPGPDG-- 146
            G+KG       PG PG PGLPG PG  G PG PGP G PG I   G RGP G+PG  G  
Sbjct: 555  GMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLP 614

Query: 147  ----PSGPPG--PPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGP-------------PG 187
                P GPPG  PPG  G  G IQG+ G+          PG+ GP             PG
Sbjct: 615  GNIGPMGPPGFGPPGPVGEKG-IQGVAGNPG-------QPGIPGPKGDPGQTITQPGKPG 666

Query: 188  LQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGP--PGPQGIRGYPGMAGPKGE 245
            L G  G  G  G+ GDPG  G+PG  G  G+ GE GIPG   PGP G +G+PG+ GP G 
Sbjct: 667  LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGA 726

Query: 246  TGPHGYKGMVGAIGATGPPGEEGPRGPPGRA--GEKGDEGSPGIRGPQGITGPKGATGPP 303
             G     G +G  G  GPPG  GP+G PG A  G  G  G PG +G  G  G +G  GPP
Sbjct: 727  PGT---PGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPP 783

Query: 304  GINGKDGTPGTPGMKGSAGQAGQPGS--------------PGHQGLAGVPGQPGTKGGPG 349
            G  G+ G  G PG KG  G  GQPG               PG  G+ G  GQPG  G PG
Sbjct: 784  GPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPG 843

Query: 350  DQGEPGPQGL--PGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGP 407
            ++G+PGP GL  PG  G  G  G PG  G IGP G  G  G  G  G  G  G  G  GP
Sbjct: 844  EKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP 903

Query: 408  KGEQGPPGIPGPQGLPGVKGDKGS------PGKTGPRGKVGDPGVAGLP--------GEK 453
             G  GP GIPG  G+PG+KGD G       PG TG +G  G+PG+ G P        G K
Sbjct: 904  PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSK 963

Query: 454  GEKGESGEP------GPKGQQGVRGEPGYPGPSGDAGAPGV------------------- 488
            GEKGE G P      GPKG QG+ G+PG PG SG  G PG                    
Sbjct: 964  GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPP 1023

Query: 489  --------QGYPGPPGPRGLAGNRGVPGQPGRQGVEGR--DATDQHIVDVALKMLQEQLA 538
                     G+PGP G  G  G  GVPGQPG  G+ G+  D  D  I  + L  L     
Sbjct: 1024 GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKG 1083

Query: 539  EVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKG 598
            E  +       G  G+ G  G PG PG PG  G  G PG  G PG  G  G  G +GP G
Sbjct: 1084 EPGLPGYP---GNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPG 1140

Query: 599  KRGEKGDPGEV-GRGHPGMPGPPGIPGLPGR------------PGQ---------AINGK 636
              G  G+PG V G GHPG PGPPG  G PG+            PGQ          + G 
Sbjct: 1141 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL 1200

Query: 637  DGDRGSPGAPGEAGRPGLPGPVGLPGF 663
             G +G  G PG  G PGLPGP G PGF
Sbjct: 1201 SGQKGDGGLPGIPGNPGLPGPKGEPGF 1227



 Score =  509 bits (1310), Expect = e-144
 Identities = 331/828 (39%), Positives = 386/828 (46%), Gaps = 176/828 (21%)

Query: 27  GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
           GPPG RG  G  G PG PG  GI G  G PG  G PG  G PG  G  GP G PG +G  
Sbjct: 69  GPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTK 128

Query: 87  GAKGEPGPMGIPGVKGQPGLPGPPG------------LPGP-GFAGPPGPPGPVGLPGEI 133
           G +G PG  G PG++G PG PG PG            LPGP G  G PGPPG  GLPG  
Sbjct: 129 GERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPT 188

Query: 134 GIRGPKGDPGPDGPSGPPGPPGKPGRPGTI-------------QGLEG------------ 168
           GI GP G PGP G  GPPGPPG PG  G +             QGL+G            
Sbjct: 189 GIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQK 248

Query: 169 ---SADFLCPTNCPPGMKGPPGLQGVK-------GHAGKRGILGDPGHQGKPGPKGDVGA 218
                +F       PG +GPPG  G++       G  G++G  G+PG +GKPG  G+ G 
Sbjct: 249 RPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQ 308

Query: 219 SGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATG-PPGEEGPRGPPGRAG 277
            G  G+PG PG  G  G  G  G KG+TGP G  G+V     TG   GE+G  G PG  G
Sbjct: 309 PGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPG 368

Query: 278 EKGDEGSPGIRGPQGITGPKGAT----------------------------GPPGINGKD 309
           EKG+ G PGI+GP G+ GP GA                             GPPG++G+ 
Sbjct: 369 EKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQP 428

Query: 310 GTPGTPGMKGSA-------------GQAGQPGSPGHQGLAGVPGQPGTKG-------GPG 349
           G PG PG  G A             G  G PGSPG +GL G  G  G KG       G G
Sbjct: 429 GAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTG 488

Query: 350 DQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPG--------- 400
             G PG  GLPG  GPPG  G PG +GE G  G  G KG  G  G  G PG         
Sbjct: 489 ISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPG 548

Query: 401 ----PQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGP------------RGKVGDP 444
                 G +G KGE G PG PG  GLPG  G  G PG  GP            RG  G+P
Sbjct: 549 DILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNP 608

Query: 445 GVAGLPGEKGEKGES--GEPGPKGQQGVR------GEPGYPGPSGD-------AGAPGVQ 489
           G+ GLPG  G  G    G PGP G++G++      G+PG PGP GD        G PG+ 
Sbjct: 609 GLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLP 668

Query: 490 GYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREAL 549
           G PG  G  GL G+ G+PGQPG  G+ G    +  I  + L           +     A 
Sbjct: 669 GNPGRDGDVGLPGDPGLPGQPGLPGIPGSKG-EPGIPGIGLPGPPGPKGFPGIPGPPGAP 727

Query: 550 GAVGMMGPPGPPGPPGYPGKQGPHGH-----PGPRGVPGIVGAV---------------- 588
           G  G +G  GPPGPPG+PG +G  G      PGP G+PG  GA+                
Sbjct: 728 GTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPG 787

Query: 589 --------GQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPG-QAINGKDGD 639
                   G  G+ GP G+ G  G PG  G G  G PGPPGIPG  G+PG   I G+ GD
Sbjct: 788 RTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGD 847

Query: 640 RGS-----PGAPGEAGRPGL---PGPVGLPGFCEPAACLGASAYASAR 679
            G      PG PGE G PG+   PGP+G PG        GAS +   +
Sbjct: 848 PGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTK 895



 Score =  475 bits (1222), Expect = e-134
 Identities = 303/728 (41%), Positives = 357/728 (49%), Gaps = 123/728 (16%)

Query: 25  IRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDG 84
           I+G  GERG PG  G PG+PG          PG  GPPGP+G+ G  G  GP        
Sbjct: 43  IKGEKGERGFPGLEGHPGLPGF---------PGPEGPPGPRGQKGDDGIPGP-------- 85

Query: 85  LTGAKGEPGPMGIPGVKGQPGLPGPPGLPG-PGFAGPPGP---PGPVGLPGEIGIRGPKG 140
                  PGP GI G  G PG PG PGLPG PG  G PGP   PG  G  GE G  G  G
Sbjct: 86  -------PGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPG 138

Query: 141 DPGPDGPSGPPGPPGKPGRPGTI-----QGLEGSADFLCPTNCPPGMKGPPGLQGVKGHA 195
            PG  GP GPPG PG  G PG+I      G +G+  +  P     G+ GP G+ G  G  
Sbjct: 139 FPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGI-QGLPGPTGIPGPIGPP 197

Query: 196 GKRGILGDPGHQGKPGPKGDVGAS--------GEQGIPGPPGPQGIRGYPGMAGPKGETG 247
           G  G++G PG  G PGPKG++G +        GEQG+ GPPGP G         P     
Sbjct: 198 GPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPG--QISEQKRPIDVEF 255

Query: 248 PHGYKGMVGAIGATGPPGEEGPRGPP-GRAGEKGDEGSPGIRGPQGITGPKGATGPPGIN 306
             G +G+ G  G  GPPG  GP GPP G  GEKG++G PG RG  G  G  G  G PG+ 
Sbjct: 256 QKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP 315

Query: 307 GKDGTPGTPGMKGSAGQAGQPGSP-------------------GHQGLAGVPGQPGTKGG 347
           G  G PG PG  G  GQ G  G P                   G+ GL G+PG+ G +G 
Sbjct: 316 GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGF 375

Query: 348 PGDQGEPGPQGLPGFS--GPPGKEGEPGPRGEIGPQG-----IMGQKGDQGERGPVGQPG 400
           PG QG PG  G PG +  GPPG  G PG RG+ G +G     I G  G  G+ G  G PG
Sbjct: 376 PGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPG 435

Query: 401 PQGRQGP----------KGEQGPPGIPGPQGL---PGVKGDKGS-------------PGK 434
           P G  GP           G  GPPG PG +GL    GVKGDKG              PG+
Sbjct: 436 PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495

Query: 435 TGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPG-VQGYPG 493
            G  G  G PG  G PG+KGEKG++G  GPKG  G+ G PG PG  G  G PG +  +PG
Sbjct: 496 PGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG 555

Query: 494 PPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKR------- 546
             G +G  G+ G PG PG  G  G+D          L   + +   +    +R       
Sbjct: 556 MKGDKGELGSPGAPGLPGLPGTPGQDGLP------GLPGPKGEPGGITFKGERGPPGNPG 609

Query: 547 --EALGAVGMMGPP--GPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQ-IGNTGPKGKRG 601
                G +G MGPP  GPPGP G  G QG  G+PG  G+PG  G  GQ I   G  G  G
Sbjct: 610 LPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669

Query: 602 EKGDPGEVG-RGHPGMPGPPGIPGLPGR------PGQAINGKDGDRGSPGAPGEAGRPGL 654
             G  G+VG  G PG+PG PG+PG+PG       PG  + G  G +G PG PG  G PG 
Sbjct: 670 NPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGT 729

Query: 655 PGPVGLPG 662
           PG +GL G
Sbjct: 730 PGRIGLEG 737



 Score =  467 bits (1202), Expect = e-131
 Identities = 284/642 (44%), Positives = 325/642 (50%), Gaps = 116/642 (18%)

Query: 25   IRGPPGERGPPG---------PPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDG 75
            + GPPGERG PG         PPG PG+PG  G  G  G  G+ G  GP G PG  G  G
Sbjct: 855  VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPG 914

Query: 76   PDGKPGI---DGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGE 132
              G PG+   DGL G  G PGP G  G KG+PGLPGPPG   P   G  G  G  GLPG 
Sbjct: 915  RSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGI 974

Query: 133  IGIRGPK------GDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGP- 185
             G+ GPK      GDPG  G SG PG PG PG  G   GL G    +     PPG+KG  
Sbjct: 975  PGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN-PGLPGQPGLI----GPPGLKGTI 1029

Query: 186  -----PGLQGVKGHAGKRGILGDPGHQGKPGPKGDVG-----ASGEQGIPGPPGPQGIRG 235
                 PG QGV+G  G  G+ G PG  G PG KGD G     + G  G+PGP G  G+ G
Sbjct: 1030 GDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPG 1089

Query: 236  YPGMAGPKGETGPHGYKGMVGAIGATGP------PGEEGPRGPPGRAGEKGDEGSPGIRG 289
            YPG  G KG  G  G  G+ G  GA G       PG  GP GP G +G  G+ G PG  G
Sbjct: 1090 YPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPG 1149

Query: 290  PQGITGPKGATGPPGINGK---DGTPGTPGMKGSAGQA--GQPGSPGHQGLAGVPGQPGT 344
            P G  G  G  GPPG  GK   DG PG  G KG  GQ   G PG PG  GL+G  G  G 
Sbjct: 1150 PVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGL 1209

Query: 345  KGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGR 404
             G PG+ G PGP+G PGF G PG +G PGP G  GP  + G KG+ G +GP G+PGP G 
Sbjct: 1210 PGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP-ALEGPKGNPGPQGPPGRPGPTGF 1268

Query: 405  QGPKGEQGPPGIPGP---------------QGLPGVKGD------KGSPGKTGPRGKVGD 443
            QG  G +GPPG+PG                 GLPG+KGD      +G+PG+ G  G  GD
Sbjct: 1269 QGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGD 1328

Query: 444  PGVAGLPGEKGEKGESGEP---GPKGQQGV---RGEPGYPGPSGDA-------------G 484
            PG+ G+PG  G KG SG P   GP+G+ G+    G PG PGPSG +             G
Sbjct: 1329 PGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPG 1388

Query: 485  APGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSA 544
             PG++G PGP GP+GL G  G PG PGR G+ G D                         
Sbjct: 1389 QPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFD------------------------- 1423

Query: 545  KREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVG 586
                 GA G  G PG PG PG  G  GP G  G +G PG  G
Sbjct: 1424 -----GAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460



 Score =  422 bits (1085), Expect = e-118
 Identities = 257/585 (43%), Positives = 295/585 (50%), Gaps = 110/585 (18%)

Query: 26   RGPPGERGPPGPPGPPGVPG---------SDGIDGDNGPPGKAGPPGPKGEPGKAGPDGP 76
            +G  G  GPPGPPGP G+PG          DG+ G  G PG  G  G KGEPG  GP GP
Sbjct: 895  KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGP 954

Query: 77   DGKPGIDGLTGAKGEPGPMGIPGV---KGQPGLPGPPGLPG----PGFAGPPGPPGPVGL 129
               P + G  G KGEPG  GIPGV   KG  GLPG PG PG    PG  GPPGP G  GL
Sbjct: 955  MD-PNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGL 1013

Query: 130  PGEIGIRGPKG---------DPGPDGPSGPPGPPGKPGRPGTIQGLEGSADF-----LCP 175
            PG+ G+ GP G          PGP G  GPPGP G PG+PG+  GL G         +  
Sbjct: 1014 PGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGS-PGLPGQKGDKGDPGISS 1072

Query: 176  TNCP--PGMKGPPGLQGVKGHAGKRGILGDPGHQG---KPGPKGDVGASGEQGIPGPPGP 230
               P  PG KG PGL G  G+ G +G +GDPG  G    PG KG  G  G  G PGPPGP
Sbjct: 1073 IGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGP 1132

Query: 231  QGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGP 290
            +GI G PG  G  GE GP G  G  G  G  G  G+ G  G PG AG+KG+ G PG   P
Sbjct: 1133 KGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNP 1192

Query: 291  QGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGD 350
                   G  G PG++G+ G  G PG+ G+ G  G  G PG  G  GV G PG  G PG 
Sbjct: 1193 -------GPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP 1245

Query: 351  -----QGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQ 405
                 +G PGPQG PG  GP G +G PGP G   P G+ G  G +GE+G  GQPG  G  
Sbjct: 1246 ALEGPKGNPGPQGPPGRPGPTGFQGLPGPEG---PPGLPGNGGIKGEKGNPGQPGLPGLP 1302

Query: 406  GPKGEQGPPGI------------------PGPQGLPGVKGDKGSPGKTGPRGK---VGDP 444
            G KG+QGPPG+                  PG  G PG+KG  G PG  GP G+   +G P
Sbjct: 1303 GLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPP 1362

Query: 445  GVAGLPGEKGE----KGESGEPGPKGQQGVRGEPGYPGPSG------------------- 481
            G  GLPG  G+    KG++G PG  GQ G++G PG  GP G                   
Sbjct: 1363 GPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGF 1422

Query: 482  --------DAGA---PGVQGYPGPPGPRGLAGNRGVPGQPGRQGV 515
                    D G    PG +G  GPPGP GL   +G PG PG   V
Sbjct: 1423 DGAGGRKGDPGLPGQPGTRGLDGPPGPDGL---QGPPGPPGTSSV 1464



 Score =  376 bits (965), Expect = e-104
 Identities = 244/596 (40%), Positives = 291/596 (48%), Gaps = 119/596 (19%)

Query: 181 GMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGM- 239
           G+KG  G +G  G  G  G+ G PG +G PGP+G     G+ GIPGPPGP+GIRG PG+ 
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQ---KGDDGIPGPPGPKGIRGPPGLP 98

Query: 240 -----------------AGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDE 282
                             GP+G  G +G KG  G  G+ G PG +GP GPPG  G KG+ 
Sbjct: 99  GFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEP 158

Query: 283 GS------------------PGIR---GPQGITGPKGATGPPGINGKDGTPGTPGMKGSA 321
           GS                  PGI+   GP GI GP G  GPPG+ G  G PG PG KG+ 
Sbjct: 159 GSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNM 218

Query: 322 GQ--AGQPGSPGHQGLAGVPGQP----------------GTKGGPGDQGEPGPQGLPGFS 363
           G    G  G  G QGL G PG P                G +G PGD+G PGP G+ G  
Sbjct: 219 GLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPP 278

Query: 364 GPP-------GKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGI 416
           GPP       G++GEPG RG+ G  G  GQ G  G  G  G PG  GR G KG++G  G 
Sbjct: 279 GPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGP 338

Query: 417 PGPQGLP----------GVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGES------- 459
           PGP GL           G KG+ G PG  G +G+ G PG+ G PG  G  G +       
Sbjct: 339 PGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGP 398

Query: 460 -GEPGPKGQQGVRGEPG--YPGPSGDAGAPGVQGYPGPPGPRG----------LAGNRGV 506
            G PG +GQ+G  G PG   PGP G  G PG  G PGPPGP G            G  G 
Sbjct: 399 PGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGP 458

Query: 507 PGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGY 566
           PG PG +G++G         D     +        +S      G  G+ GPPG  G PG 
Sbjct: 459 PGSPGDKGLQGEQGVKGDKGDTCFNCI-----GTGISGPPGQPGLPGLPGPPGSLGFPGQ 513

Query: 567 PGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGE-------KGDPGEVGR----GHPG 615
            G++G  G  GP+G+PGI GA G  G  G KG+ G+       KGD GE+G     G PG
Sbjct: 514 KGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573

Query: 616 MPGPPGIPGLPGRPGQ-----AINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEP 666
           +PG PG  GLPG PG       I  K G+RG PG PG  G PG  GP+G PGF  P
Sbjct: 574 LPGTPGQDGLPGLPGPKGEPGGITFK-GERGPPGNPGLPGLPGNIGPMGPPGFGPP 628



 Score =  365 bits (936), Expect = e-100
 Identities = 236/598 (39%), Positives = 283/598 (47%), Gaps = 123/598 (20%)

Query: 178 CPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYP 237
           C PG K      G+KG  G+RG  G  GH G PG        G +G PGP G +G  G P
Sbjct: 32  CSPGSKCD--CSGIKGEKGERGFPGLEGHPGLPG------FPGPEGPPGPRGQKGDDGIP 83

Query: 238 GMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPK 297
           G  GPKG  GP G  G  G  G  G PG +G  GP         +G PG  G +G  G  
Sbjct: 84  GPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGP---------QGIPGCNGTKGERGFP 134

Query: 298 GATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEP--- 354
           G+ G PG+ G  G PG PGMKG  G       PG +G  G PG PG +G PG  G P   
Sbjct: 135 GSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPI 194

Query: 355 GPQGLPGFSGPPGKEGEPGPRGEIGP--QGIMGQKGDQGERGPVGQP------------- 399
           GP G PG  GPPG  G PGP+G +G   QG  G+KG+QG +GP G P             
Sbjct: 195 GPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVE 254

Query: 400 ---GPQGRQGPKGEQGPPGIPGPQGLP----GVKGDKGSPGKTGPRGKVGD---PGVAGL 449
              G QG  G +G  GPPGI GP G P    G KG++G PGK G  GK G+   PG+ GL
Sbjct: 255 FQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGL 314

Query: 450 P------------GEKGEKGESGEPGPK-------------GQQGVRGEPGYPGPSGDAG 484
           P            GEKG+KG++G PGP              G++G  G PG PG  G+ G
Sbjct: 315 PGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERG 374

Query: 485 APGVQGYPGPPGPRGLA--GNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAV 542
            PG+QG PG PGP G A  G  G PG PG +G +G    D+    +++           +
Sbjct: 375 FPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKG----DEGPPGISIP------GPPGL 424

Query: 543 SAKREALGAVGMMGP-------------PGPPGPPGYPGKQGPHGH-------------- 575
             +  A G  G  GP             PGPPGPPG PG +G  G               
Sbjct: 425 DGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNC 484

Query: 576 -----PGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-RGHPGMPGPPGIPGLPGRP 629
                 GP G PG+ G  G  G+ G  G++GEKG  G  G +G PG+PG PG PG PG  
Sbjct: 485 IGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSK 544

Query: 630 GQ--------AINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASAR 679
           G+         + G  G+ GSPGAPG  G PG PG  GLPG   P    G   +   R
Sbjct: 545 GEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGER 602



 Score =  300 bits (767), Expect = 4e-81
 Identities = 183/446 (41%), Positives = 217/446 (48%), Gaps = 68/446 (15%)

Query: 274 GRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQ 333
           G  GEKG+ G PG+ G  G+ G  G  GPPG  G+ G  G PG  G  G  G PG PG  
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP 101

Query: 334 GLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGER 393
           G  G+PG PG  G PG QG PG  G  G  G PG  G PG +G  GP GI G KG+ G  
Sbjct: 102 GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSI 161

Query: 394 GPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPG-------- 445
                PGP+G  G  G  G  G+PGP G+PG  G  G PG  GP G  G PG        
Sbjct: 162 IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLN 221

Query: 446 VAGLPGEKGEKGESGEPGPKGQ----------QGVRGEPGYPGPSGDAGAPGVQGYPGPP 495
             G  GEKGE+G  G PGP GQ          +  +G+ G PG  G  G PG++G PGPP
Sbjct: 222 FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPP 281

Query: 496 GPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMM 555
           G  G  G +G  G+PG++G  G+D                         +    G  G+ 
Sbjct: 282 G--GEKGEKGEQGEPGKRGKPGKD------------------------GENGQPGIPGLP 315

Query: 556 GPPGPPGPPGYPGKQGPHGHPGPRGVPGIV----------GAVGQIGNTGPKGKRGEKGD 605
           G PG PG PG  G++G  G  GP G PG+V          G  G IG  G  G++GE+G 
Sbjct: 316 GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGF 375

Query: 606 PGEVGRGHPGMPGPPGI-----PGLPGRPGQAINGKDGDRGSPG--APGEAGRPGLPGPV 658
           PG   +G PG+PGPPG      PG PG PG+   G+ GD G PG   PG  G  G PG  
Sbjct: 376 PGI--QGPPGLPGPPGAAVMGPPGPPGFPGE--RGQKGDEGPPGISIPGPPGLDGQPGAP 431

Query: 659 GLPGFCEPAACLGASAYASARLTEPG 684
           GLPG   P    G     S  + EPG
Sbjct: 432 GLPG---PPGPAGPHIPPSDEICEPG 454



 Score =  222 bits (565), Expect = 1e-57
 Identities = 143/357 (40%), Positives = 169/357 (47%), Gaps = 84/357 (23%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGK------- 79
            GPPG +G  GPPG PG+PG  G  G  G PG+ GPPG KG+PG+ G  GP G+       
Sbjct: 1128 GPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQP 1187

Query: 80   -------PGIDGLTGAKGE------PGPMGIPGVKGQPGL---------PGPPGLPGP-- 115
                   PG+ GL+G KG+      PG  G+PG KG+PG          PGPPG PGP  
Sbjct: 1188 GFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPAL 1247

Query: 116  -------------------GFAGPPGPPGPVGLPGEIGIRGPKGDPGPDG---------P 147
                               GF G PGP GP GLPG  GI+G KG+PG  G          
Sbjct: 1248 EGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGD 1307

Query: 148  SGPPGPPGKPGRPGTIQGLEGSADFLCPTNCP--PGMKGPPGLQGVKGHAGKRGILGDPG 205
             GPPG  G PGRPG + G++G          P  PGMKGP G+ G  G  G+ G++G PG
Sbjct: 1308 QGPPGLQGNPGRPG-LNGMKGDPGL---PGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPG 1363

Query: 206  HQGKPGP-------KGDVGASGE------QGIPGPPGPQGI------RGYPGMAGPKGET 246
              G PGP       KGD G  G       +G+PGP GPQG+       G PG  G  G  
Sbjct: 1364 PPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFD 1423

Query: 247  GPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPP 303
            G  G KG  G  G  G  G +GP GP G  G  G  G+  +     IT     T  P
Sbjct: 1424 GAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAP 1480



 Score =  146 bits (369), Expect = 5e-35
 Identities = 85/179 (47%), Positives = 100/179 (55%), Gaps = 16/179 (8%)

Query: 22   LAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPG 81
            L  + G  G++GPPG  G PG PG +G+ GD G PG  G PG KG  G  G  GP+G+PG
Sbjct: 1298 LPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPG 1357

Query: 82   IDGLTGAKGEPGPMG----IPGVKGQPGLPGPPGLPG-PGFAGPPGPPGPVGLPGEIGIR 136
            + G  G  G PGP G    I G  G PG+PG PGL G PG  GP G PGP G PG+    
Sbjct: 1358 LIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGD---P 1414

Query: 137  GPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHA 195
            G  G PG DG  G  G PG PG+PGT +GL+G          P G++GPPG  G    A
Sbjct: 1415 GRNGLPGFDGAGGRKGDPGLPGQPGT-RGLDGPPG-------PDGLQGPPGPPGTSSVA 1465



 Score =  130 bits (326), Expect = 5e-30
 Identities = 91/247 (36%), Positives = 103/247 (41%), Gaps = 70/247 (28%)

Query: 462 PGPK----GQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEG 517
           PG K    G +G +GE G+PG  G  G PG  G  GPPGPRG  G+ G+PG PG +    
Sbjct: 34  PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPK---- 89

Query: 518 RDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGH-- 575
                                              G+ GPPG PG PG PG  G  GH  
Sbjct: 90  -----------------------------------GIRGPPGLPGFPGTPGLPGMPGHDG 114

Query: 576 -PGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAIN 634
            PGP+G+PG           G KG+RG  G PG  G   P  PGPPGIPG+ G PG  I 
Sbjct: 115 APGPQGIPGC---------NGTKGERGFPGSPGFPGLQGP--PGPPGIPGMKGEPGSIIM 163

Query: 635 ----GKDGDRGSPGAPGEAGRPGL---------PGPVGLPGFCEPAACLGASAYASARLT 681
               G  G+ G PG PG  G PG          PGP GL G   P    G          
Sbjct: 164 SSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQ 223

Query: 682 EPGSIKG 688
            P   KG
Sbjct: 224 GPKGEKG 230


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score =  548 bits (1412), Expect = e-156
 Identities = 324/726 (44%), Positives = 377/726 (51%), Gaps = 100/726 (13%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
            G PG  GP G PG  G PG+ G+ G+ GP G  GP GP+G+ G+ GP GP G PG+ G  
Sbjct: 363  GKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAI 422

Query: 87   GAKGEPG---PMGIPGVKGQPGLPGPPGLPGP----------------------GFAGPP 121
            G  G PG   P G PG  G PG  GPPG PGP                      G AGP 
Sbjct: 423  GTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPK 482

Query: 122  GPPGP------VGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGR---PGT--IQGLEGSA 170
            G PGP      +G PGE G RGP+GDPG  GP GP G  G PG    PG+  + G +G+ 
Sbjct: 483  GEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQ 542

Query: 171  DFLCPTNC--PPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPP 228
                P     P G +G PG  G  G  G RG+ G+PG QG  G  G +GA GE G PGPP
Sbjct: 543  GERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPP 602

Query: 229  GPQGIRGYPG---MAGPKG---------ETGPHGYKGMVGAIGATGPPGEEGPRGPPGRA 276
            G  GIRG PG   + GPKG         E G  G  G  GA G  G  G  GP GPPG A
Sbjct: 603  GSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLA 662

Query: 277  GEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLA 336
            GE+G++G PG  G QG+ GP G  G  G  G  G PG PG  G  G  G+ G+PG +G  
Sbjct: 663  GERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEP 722

Query: 337  GVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPV 396
            G+ G PG KG  G  G  GP+G PG SG PG  G PG +G  G +GI G  G +G+RG +
Sbjct: 723  GITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGI 782

Query: 397  GQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEK 456
            G+   +G +G  G  G  G+PGP G PG  G  G  G+ GPRG VG PG  G PG +GE 
Sbjct: 783  GE---KGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGEN 839

Query: 457  GESGE------PGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPR------GLAGNR 504
            G +G        GP GQ GV+GEPG PG  GDAG+PG QG  G PGP       GL G R
Sbjct: 840  GPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGR 899

Query: 505  GVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPP 564
            G  G PG  G  G                         SA R  +G  G  G PGP GP 
Sbjct: 900  GTQGPPGATGFPG-------------------------SAGR--VGPPGPAGAPGPAGPL 932

Query: 565  GYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPG 624
            G PGK+GP   PG RG PG  G VG  G  GP G  G+KGDPGE   G PG  GPPG  G
Sbjct: 933  GEPGKEGP---PGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGE--DGQPGPDGPPGPAG 987

Query: 625  LPGRPG-QAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASARLTEP 683
              G+ G   + G+ G+RG PG PG AG PG  GP G  G   P   +G    ++  + EP
Sbjct: 988  TTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPG-SNGPVGEP 1046

Query: 684  GSIKGP 689
            G  +GP
Sbjct: 1047 GP-EGP 1051



 Score =  528 bits (1360), Expect = e-150
 Identities = 319/747 (42%), Positives = 369/747 (49%), Gaps = 117/747 (15%)

Query: 23  AQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGI 82
           +Q+   PG  GP GP GP G+ G  G  G  GPPG+ G PGP G  G  GP+GP GKPG 
Sbjct: 206 SQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGE 265

Query: 83  DGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPG-------------------PGFAGPPGP 123
           DG  G  G PG +G  G  G  G PG PGLPG                   PG  G  GP
Sbjct: 266 DGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGP 325

Query: 124 PGPVGLPGEIGIRGPKGDPGPDGPSGPPGP------PGKPGRPGTIQGLEGSADF----- 172
            GP+G  G +G RG  G+ G  GP G PG       PGKPG  G + G+ GS+ F     
Sbjct: 326 TGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPL-GIPGSSGFPGNPG 384

Query: 173 ----LCPTNC--------------PPGMKGPPGL---------QGVKGHAGKRGILGDPG 205
                 PT                PPG  G PGL          G KG  G  G  G PG
Sbjct: 385 MKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPG 444

Query: 206 HQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGA-------- 257
             G PG  G  G++G QGI G PG  G+ G+ G AGPKGE GPHG +G +G         
Sbjct: 445 SAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRG 504

Query: 258 ----IGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPG 313
                G  GPPG  G RG PG  G  G +G PG +G QG  GP G++GP G  G  G PG
Sbjct: 505 PRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPG 564

Query: 314 TPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGD------QGEPGPQGLPGFSGPPG 367
            PG+ G+ G  G PG  G +G  G  G PG  G PG       +G+PG  GLPG  G  G
Sbjct: 565 EPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSG 624

Query: 368 KEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKG 427
             G+PG  G  G  G  G  G  GE GP G  GP G  G +GEQGPPG  G QGLPG  G
Sbjct: 625 DPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPG 684

Query: 428 DKGSPGKTGPRGKVGDPGVAGLPGEKGEK---GESGEPGPKGQQGVRGEPGYPGPSGDAG 484
             G  GK G +G  GDPG  G  G +GE+   GE GEPG  G  G +G  G  GP G  G
Sbjct: 685 PPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKG 744

Query: 485 APGVQGYP---GPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVA 541
           +PG  G P   GPPG +G+ G RG+ G PG +G  G               + E+ AE  
Sbjct: 745 SPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGG--------------IGEKGAE-G 789

Query: 542 VSAKREALGAVGMMGPPGPPGPPGYPGKQGP---------HGHPGPRGVPGIVGAVGQIG 592
            +    A G  G +GPPGP GP G  G+ GP          G+PG RG  G  GAVG  G
Sbjct: 790 TAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAG 849

Query: 593 NTGPKGKRGEKGDPGEVG-RGHPGMPGPPGIPGLPGRPG----QAINGKDGDRGSPGA-- 645
             GP G+ G KG+PGE G +G  G PGP G+ G PG  G      + G  G +G PGA  
Sbjct: 850 PQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATG 909

Query: 646 -PGEAGRPGLPGPVGLPGFCEPAACLG 671
            PG AGR G PGP G PG   PA  LG
Sbjct: 910 FPGSAGRVGPPGPAGAPG---PAGPLG 933



 Score =  516 bits (1330), Expect = e-146
 Identities = 300/680 (44%), Positives = 346/680 (50%), Gaps = 61/680 (8%)

Query: 26   RGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGL 85
            RGP G  GP G  G PG PG  G+ G  G  G  G  GP+G+ G  G  G DG+PG  G 
Sbjct: 545  RGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGS 604

Query: 86   TGAKGEPGPMGIPGVKGQPGLPGPPG------LPG----PGFAGPPGPPGPVGLPGEIGI 135
             G +G+PG MG+PG KG  G PG PG      +PG    PG  G  GP GPVG PG  G 
Sbjct: 605  IGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGE 664

Query: 136  RGPKGDPGP---DGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCP-----PGMKGPPG 187
            RG +G PGP    G  GPPGPPG+ G+PG  QG+ G    + P         PG +G PG
Sbjct: 665  RGEQGPPGPTGFQGLPGPPGPPGEGGKPGD-QGVPGDPGAVGPLGPRGERGNPGERGEPG 723

Query: 188  LQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETG 247
            + G+ G  G  G  G  G +G PGP G  G +G  G+ G PG +GI G PG  G +G  G
Sbjct: 724  ITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIG 783

Query: 248  PHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGP---------QGITGPKG 298
              G +G  G  GA G PG  GP GP G  GEKG+ G  G+ GP         +G  GP G
Sbjct: 784  EKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTG 843

Query: 299  ATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPG---DQGEPG 355
            A G  G  G DG PG  G  G  GQ G  GSPG QGLAG PG  G  G PG    +G  G
Sbjct: 844  AVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQG 903

Query: 356  PQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPG 415
            P G  GF G  G+ G PGP G  GP G +G+ G +G  G  G PG  GR G +G  GPPG
Sbjct: 904  PPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPG 963

Query: 416  IPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKG---QQGVRG 472
             PG +G PG  G  G  G  GP G  G  G+ G+PG++GE+G  G PGP G   + G  G
Sbjct: 964  GPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTG 1023

Query: 473  EPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKM 532
              G  GP G  G PG  G  G PGP G AGN G PG+ G  G  G D  D          
Sbjct: 1024 ATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERG-DRGDPG-------- 1074

Query: 533  LQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIG 592
                             G  G  G PG PGP G PG  G  G PG RG  G  G  G+ G
Sbjct: 1075 ---------------PAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRG 1119

Query: 593  NTGPKGKRGEKGDPGEVG-RGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGR 651
              GP+G RG+KGD G+ G RG  G  G  G+ GLPG PG   NG+ G  G PG  G  G 
Sbjct: 1120 LPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGP--NGEQGSAGIPGPFGPRGP 1177

Query: 652  PGLPGPVGLPGFCEPAACLG 671
            PG  GP G  G   P   +G
Sbjct: 1178 PGPVGPSGKEGNPGPLGPIG 1197



 Score =  513 bits (1322), Expect = e-145
 Identities = 298/680 (43%), Positives = 351/680 (51%), Gaps = 69/680 (10%)

Query: 18  VVLALAQIRGPPGERGPPGPPGP---------PGVPGSDGIDGDNGPPGKAGPPGPKGEP 68
           +V  +  IRG PG  GPPG  GP         PG  G  GIDG+ G PG+ G PGP G P
Sbjct: 120 LVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHP 179

Query: 69  GKAGPDG-----PDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPG-PGFAGPPG 122
              GPDG          G+D  +G   + G M  PG  G  G  GP GL G  G AGP G
Sbjct: 180 SHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLM--PGSVGPVGPRGPQGLQGQQGGAGPTG 237

Query: 123 PPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGM 182
           PPG  G PG +G  G +G  GP G  G  G PG+ G PG + G  GS           G 
Sbjct: 238 PPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEV-GFAGSPG-------ARGF 289

Query: 183 KGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGP 242
            G PGL G+KGH G +G+ G  G  G PG KG+ G +G  G  GP GP+G+ G  G  GP
Sbjct: 290 PGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGP 349

Query: 243 KGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGP 302
           +G  G  G  GM G  G  GP G  G  G PG  G KG+ G  G RGP+G  G +G TGP
Sbjct: 350 QGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGP 409

Query: 303 ------PGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGP 356
                 PG+ G  GT GTPG KG  G  G  G PG  G  G PG  G+ G  G +G+PG 
Sbjct: 410 PGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGD 469

Query: 357 QGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPP-- 414
            G+PGF G  G +GEPGP G  GP   +G  G++G+RGP G PG  G  GP GE+G P  
Sbjct: 470 PGVPGFKGEAGPKGEPGPHGIQGP---IGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGN 526

Query: 415 -GIPGPQGLPGVK---GDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGV 470
            G PG  GLPG K   G++G  G +GP+G  GDPG  G PG  G +G +G PG +G +G 
Sbjct: 527 RGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGK 586

Query: 471 RGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVAL 530
            G  G PG  G  G PG  G  G PG  GL G +G  G PG+ G  G             
Sbjct: 587 LGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAG------------- 633

Query: 531 KMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQ 590
                      V  +R A G  G +GP GP GPPG  G++G  G PGP G  G+ G  G 
Sbjct: 634 --------NAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGP 685

Query: 591 IGNTGPKGKRGEKGDPGEVG-------RGHPGMPGPPGIPGLPGRPGQA-INGKDGDRGS 642
            G  G  G +G  GDPG VG       RG+PG  G PGI GLPG  G A  +G DG +GS
Sbjct: 686 PGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGS 745

Query: 643 PGAPGEAGRPGLPGPVGLPG 662
           PG  G  G  G PG  G+PG
Sbjct: 746 PGPSGTPGDTGPPGLQGMPG 765



 Score =  495 bits (1275), Expect = e-140
 Identities = 287/647 (44%), Positives = 324/647 (50%), Gaps = 56/647 (8%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
            G PGE G PGPPG  G+ G  G  G  GP G +G PG  GE G AG  G  G PG DG  
Sbjct: 591  GAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEV 650

Query: 87   GAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDG 146
            G  G  GP G+ G +G+ G PGP G  G    GPPGPPG  G PG+ G+ G  G  GP G
Sbjct: 651  GPSGPVGPPGLAGERGEQGPPGPTGFQG--LPGPPGPPGEGGKPGDQGVPGDPGAVGPLG 708

Query: 147  PSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGH 206
            P G  G PG+ G PG I GL G    +   + P G KG PG  G  G  G  G+ G PG 
Sbjct: 709  PRGERGNPGERGEPG-ITGLPGEKG-MAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGE 766

Query: 207  QG---KPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGP 263
            +G    PGPKGD G  GE+G  G  G  G RG PG  GP G  GP G KG  G  G  GP
Sbjct: 767  RGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGP 826

Query: 264  PGEEG------------------PRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGI 305
            PG  G                  P+GP G+ G KG+ G PG +G  G  GP+G  G PG 
Sbjct: 827  PGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGP 886

Query: 306  NGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGP 365
            +G +G PG  G +G+ G  G  G PG  G  G PG  G  G  G  GEPG +G PG  G 
Sbjct: 887  HGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGD 946

Query: 366  PGKEGEPGPRGEIGPQGIMGQKGDQGERG---PVGQPGPQGRQGPKGEQGPPGIPGPQGL 422
            PG  G  G RG  GP G  G KGD GE G   P G PGP G  G +G  G PG  G +G+
Sbjct: 947  PGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGM 1006

Query: 423  PGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGD 482
            PG+ G  G+PGK GP G  GD G  G  G  G  G  GEPGP+G  G  G PG  G  G+
Sbjct: 1007 PGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGE 1066

Query: 483  ---------AGAPGVQGYPGPPGP---------RGLAGNRGVPGQPGRQGVEGRDATDQH 524
                     AG PG QG PG PGP         RG  G+RG  G PGR G  G       
Sbjct: 1067 RGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGP 1126

Query: 525  IVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGI 584
              D      +    +     ++   G  G+ G PGPPGP G  G  G  G  GPRG PG 
Sbjct: 1127 RGD------KGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGP 1180

Query: 585  VGAVGQIGNTGPKGKRGEKGDPGEVG----RGHPGMPGPPGIPGLPG 627
            VG  G+ GN GP G  G  G  G VG     G PG PGPPG PG PG
Sbjct: 1181 VGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPG 1227



 Score =  457 bits (1176), Expect = e-128
 Identities = 262/593 (44%), Positives = 301/593 (50%), Gaps = 63/593 (10%)

Query: 27   GPPGERGPPGPPGPPGV---PGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGID 83
            GP G +G PGPPGPPG    PG  G+ GD G  G  GP G +G PG+ G  G  G PG  
Sbjct: 672  GPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEK 731

Query: 84   GLTGAKGEPGPMGIPGVKGQPGLPGPPGLPG-PGFAGPPGPPGPVGLPGEIGIRGPKGD- 141
            G+ G  G  GP G PG  G PG  GPPGL G PG  G  G PGP G  G IG +G +G  
Sbjct: 732  GMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTA 791

Query: 142  --------PGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKG 193
                    PGP GP GP GP G+ G PG  +GL G          PPG +G PG +G  G
Sbjct: 792  GNDGARGLPGPLGPPGPAGPTGEKGEPGP-RGLVG----------PPGSRGNPGSRGENG 840

Query: 194  HAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKG 253
              G  G  G  G  G+PG KG+ G  G++G  G PGPQG+ G PG  GP G  G  G +G
Sbjct: 841  PTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRG 900

Query: 254  MVGAIGATGPPGEEGPRGPPGRAGEKGDEG---SPGIRGPQGITGPKGATGPPGINGKDG 310
              G  GATG PG  G  GPPG AG  G  G    PG  GP G+ G  G+ G  G  G  G
Sbjct: 901  TQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAG 960

Query: 311  TPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGE------PGPQGLPGFSG 364
             PG PG KG  G+ GQPG  G  G AG  GQ G  G PG +GE      PGP G PG  G
Sbjct: 961  PPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVG 1020

Query: 365  PPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQG------PPGIPG 418
            P G  G+ GP G +GP G  G  G+ G  GP G  G  GR G  GE+G      P G+PG
Sbjct: 1021 PTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPG 1080

Query: 419  PQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPG 478
             QG PG  G  G+PG  G RG  G  G  G PG  G++G  G  GP+G +G  G+ G  G
Sbjct: 1081 SQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRG 1140

Query: 479  PSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLA 538
              G  G  G+QG PGPPGP G  G+ G+PG  G +G  G                     
Sbjct: 1141 QKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPG--------------------- 1179

Query: 539  EVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQI 591
             V  S K    G  G +GP GPPG  G  G+ GP G PG  G PG  G  G +
Sbjct: 1180 PVGPSGKE---GNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHL 1229



 Score =  284 bits (726), Expect = 2e-76
 Identities = 162/356 (45%), Positives = 181/356 (50%), Gaps = 27/356 (7%)

Query: 25   IRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDG 84
            + G  G RG  GPPG  G PGS G  G  GP G  GP GP GEPGK GP G  G PG  G
Sbjct: 892  VPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHG 951

Query: 85   LTGAKGEPGPMGIPGVKGQPGLPGPPGLPG-PGFAGPPGPPGPVGLPGEIGIRGPKGDPG 143
              G +G  GP G PG KG PG  G PG  G PG AG  G  G VG+PG+ G RG  G PG
Sbjct: 952  RVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPG 1011

Query: 144  PDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGD 203
            P G  G  GP G  G  G                 PPG  GPPG  G  G  G     G 
Sbjct: 1012 PAGTPGKVGPTGATGDKG-----------------PPGPVGPPGSNGPVGEPGPE---GP 1051

Query: 204  PGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGP 263
             G+ G PG  G VG  G++G PGP G  G +G PG  GP G  G  G +G  G+ G  GP
Sbjct: 1052 AGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGP 1111

Query: 264  PGE------EGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGM 317
            PG        GP+GP G  G+ GD G  G +G +G TG +G  GPPG NG+ G+ G PG 
Sbjct: 1112 PGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGP 1171

Query: 318  KGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPG 373
             G  G  G  G  G +G  G  G  G  G  G  GE GP+G PG  GPPG  G PG
Sbjct: 1172 FGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPG 1227


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score =  546 bits (1408), Expect = e-155
 Identities = 329/757 (43%), Positives = 380/757 (50%), Gaps = 111/757 (14%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKA--GPDGPDGKPGIDG 84
            GPPG +G PG PGPPG PG+ G  G  GPPG  G PGPKGEPG A  GP GP G PG  G
Sbjct: 710  GPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG 769

Query: 85   LTGAKGE------------------PGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPG- 125
              G KG+                  PGP G  G  GQPG  GPPGLPG G  GPPGPPG 
Sbjct: 770  ALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI 829

Query: 126  --PVGLPGEIGIRGPKGDPGPDG--------------------PSGPPGPPGKPGRPGT- 162
              P+G PG  GI G KGDPGP G                    P GPPG PG PG+ G  
Sbjct: 830  PGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889

Query: 163  -IQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGE 221
               G +G    + P   PPG  G PG  GV G  G  G+ G PG    PGP G+ G+ GE
Sbjct: 890  GFPGTKGEMGMMGPPG-PPGPLGIPGRSGVPGLKGDDGLQGQPG---LPGPTGEKGSKGE 945

Query: 222  QGIPGPPGP--------QGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPP 273
             G+PGPPGP        +G +G PG+ G  G +GP GY+G+ G  G  G  G+ G  GPP
Sbjct: 946  PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPP 1005

Query: 274  GRAGEKGDEGSPGIRGPQGITG---------PKGATGPPGINGKDGTPGTPGMKGSAGQA 324
            G  G  G  G PG+ GP G+ G         P+G  GPPG +G  G PG+PG+ G  G  
Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065

Query: 325  GQPG-----------SPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPG 373
            G PG             G  GL G PG PG KG  GD G PG  G PG  G PG  G PG
Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG 1125

Query: 374  PRGEIGPQGIMGQKGDQG---ERGPVGQPGPQGRQGPKGEQGPPG---IPGPQGLPGVKG 427
              G  GP+GI G  G+ G   E GPVG  G  G+ GP GE+G PG   IPGP G  G  G
Sbjct: 1126 TPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG 1185

Query: 428  -----DKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGD 482
                 + G PG  G  G+ GD G+ G+PG  G  G  GEPG  G  GV+G PG PG  G 
Sbjct: 1186 QPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP 1245

Query: 483  A-----GAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQL 537
            A     G PG QG PG PG +GL G  G PG PG  G++G            L  L+   
Sbjct: 1246 ALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQ 1305

Query: 538  AEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPG---PRGVPGIVGAVGQIGNT 594
                +       G  GM G PG PG PG+PG +GP G PG   P G PG++G  G  G  
Sbjct: 1306 GPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLP 1365

Query: 595  GPKGK----RGEKGDPGEVGR----------GHPGMPGPPGIPGLPGRPG-QAINGKDGD 639
            GP G+    +G+ G PG  G+          G  G+PGP G PG PGR G    +G  G 
Sbjct: 1366 GPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGR 1425

Query: 640  RGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYA 676
            +G PG PG+ G  GL GP G  G   P    G S+ A
Sbjct: 1426 KGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1462



 Score =  518 bits (1335), Expect = e-147
 Identities = 331/804 (41%), Positives = 392/804 (48%), Gaps = 160/804 (19%)

Query: 19   VLALAQIRGPPGERGPPGPPGPPGVPGSDGID------------------GDNGPPGKA- 59
            +L    ++G  GE G PG PG PG+PG+ G D                  G+ GPPG   
Sbjct: 550  ILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPG 609

Query: 60   ----------------GPPGPKGE---------PGKAGPDGPDG---------------- 78
                            GPPGP GE         PG+ G  GP G                
Sbjct: 610  LPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669

Query: 79   ------------------KPGIDGLTGAKGEPGPMGI-----PGVKGQPGLPGPPGLPG- 114
                              +PG+ G+ G+KGEPG  GI     PG KG PG+PGPPG PG 
Sbjct: 670  NPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGT 729

Query: 115  ------------PGFAGP--------PGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPP 154
                        PGF GP        PGPPGP GLPG  G  GPKGD G  GP GPPG  
Sbjct: 730  PGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRT 789

Query: 155  GKPGRPGT--IQGLEGSADFLCPTNCPP-GMKGPPGLQGVKGHAGKRGILGDPGHQGKPG 211
            G  G PG     G  G    + P   P  G++GPPG  G+ G  G+ G+ G PG +G PG
Sbjct: 790  GLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPG 849

Query: 212  PKG-DV-GASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGP 269
            P G DV G  GE+G PG PG  G  G PG  G  G+ G  G+ G  G +G  GPPG  GP
Sbjct: 850  PPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGP 909

Query: 270  RGPPGRAGEKGDEGSPGIRGPQGITGP---KGATGPPGINGKDGTPGTPGMKGSAGQAGQ 326
             G PGR+G  G +G  G++G  G+ GP   KG+ G PG+ G  G P  P + GS G+ G+
Sbjct: 910  LGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG-PMDPNLLGSKGEKGE 968

Query: 327  PGSP---------GHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGE 377
            PG P         G+QGL G PGQPG  G PG  G PGP+G PG  G PG  G PG +G 
Sbjct: 969  PGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGT 1028

Query: 378  IGPQGIMGQKGDQGERGP---VGQPGPQGRQGPKGEQGPPGIP--GPQGLPGVKGD---K 429
            IG  G  G +G +G  GP    GQPG  G  G KG++G PGI   G  GLPG KG+    
Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP 1088

Query: 430  GSPGKTGPRGKVGDPGVAGLPGEKGEKGE---------SGEPGPKGQQGVRGEPGYPGPS 480
            G PG  G +G VGDPG+ GLPG  G KG+          G PGPKG  G  G PG PG  
Sbjct: 1089 GYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEP 1148

Query: 481  GDAGAPGVQGYPGPPGPRGL---------AGNRGVPGQP--GRQGVEGRDATDQHIVDVA 529
            G  G  G  G PGPPG +G          AG +G PGQP  G  G  G         D  
Sbjct: 1149 GPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGG 1208

Query: 530  LKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVG 589
            L  +           +    G  G+ GPPGPPG PG P  +GP G+PGP+G PG  G  G
Sbjct: 1209 LPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQGPPGRPGFQG 1267

Query: 590  QIGNTGPKGK------RGEKGDPGEVG-RGHPGMPGPPGIPGLPGRPGQAINGKDGDRGS 642
              G  GP G       +GEKG+PG+ G  G PG+ G  G PGL G PG+   G +G +G 
Sbjct: 1268 LPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRP--GLNGMKGD 1325

Query: 643  PGAPGEAGRPGLPGPVGLPGFCEP 666
            PG PG  G PG+ GP G+PG   P
Sbjct: 1326 PGLPGVPGFPGMKGPSGVPGSAGP 1349



 Score =  509 bits (1312), Expect = e-144
 Identities = 336/807 (41%), Positives = 377/807 (46%), Gaps = 184/807 (22%)

Query: 27   GPPGERGP----------PGPPGPPGVPGSDGIDGDNG---------------------- 54
            GPPG  GP          PGPPGPPG PG  G+ G+ G                      
Sbjct: 435  GPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPG 494

Query: 55   ---------PPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMG-------IP 98
                     PPG  G PG KGE G+AG  GP G PGI G  GA G PG  G        P
Sbjct: 495  QPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFP 554

Query: 99   GVKGQ------PGLPGPPGLPG-PGFAGPPGPPGPVGLPGEI---GIRGPKGDPGPDG-- 146
            G+KG       PG PG PGLPG PG  G PG PGP G PG I   G RGP G+PG  G  
Sbjct: 555  GMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLP 614

Query: 147  ----PSGPPG--PPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGP-------------PG 187
                P GPPG  PPG  G  G IQG+ G+          PG+ GP             PG
Sbjct: 615  GNIGPMGPPGFGPPGPVGEKG-IQGVAGNPG-------QPGIPGPKGDPGQTITQPGKPG 666

Query: 188  LQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGP--PGPQGIRGYPGMAGPKGE 245
            L G  G  G  G+ GDPG  G+PG  G  G+ GE GIPG   PGP G +G+PG+ GP G 
Sbjct: 667  LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGA 726

Query: 246  TGPHGYKGMVGAIGATGPPGEEGPRGPPGRA--GEKGDEGSPGIRGPQGITGPKGATGPP 303
             G     G +G  G  GPPG  GP+G PG A  G  G  G PG +G  G  G +G  GPP
Sbjct: 727  PGT---PGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPP 783

Query: 304  GINGKDGTPGTPGMKGSAGQAGQPGS--------------PGHQGLAGVPGQPGTKGGPG 349
            G  G+ G  G PG KG  G  GQPG               PG  G+ G  GQPG  G PG
Sbjct: 784  GPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPG 843

Query: 350  DQGEPGPQGL--PGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGP 407
            ++G+PGP GL  PG  G  G  G PG  G IGP G  G  G  G  G  G  G  G  GP
Sbjct: 844  EKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP 903

Query: 408  KGEQGPPGIPGPQGLPGVKGDKGS------PGKTGPRGKVGDPGVAGLP--------GEK 453
             G  GP GIPG  G+PG+KGD G       PG TG +G  G+PG+ G P        G K
Sbjct: 904  PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSK 963

Query: 454  GEKGESGEP------GPKGQQGVRGEPGYPGPSGDAGAPGV------------------- 488
            GEKGE G P      GPKG QG+ G+PG PG SG  G PG                    
Sbjct: 964  GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPP 1023

Query: 489  --------QGYPGPPGPRGLAGNRGVPGQPGRQGVEGR--DATDQHIVDVALKMLQEQLA 538
                     G+PGP G  G  G  GVPGQPG  G+ G+  D  D  I  + L  L     
Sbjct: 1024 GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKG 1083

Query: 539  EVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKG 598
            E  +       G  G+ G  G PG PG PG  G  G PG  G PG  G  G  G +GP G
Sbjct: 1084 EPGLPGYP---GNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPG 1140

Query: 599  KRGEKGDPGEV-GRGHPGMPGPPGIPGLPGR------------PGQ---------AINGK 636
              G  G+PG V G GHPG PGPPG  G PG+            PGQ          + G 
Sbjct: 1141 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL 1200

Query: 637  DGDRGSPGAPGEAGRPGLPGPVGLPGF 663
             G +G  G PG  G PGLPGP G PGF
Sbjct: 1201 SGQKGDGGLPGIPGNPGLPGPKGEPGF 1227



 Score =  509 bits (1310), Expect = e-144
 Identities = 331/828 (39%), Positives = 386/828 (46%), Gaps = 176/828 (21%)

Query: 27  GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
           GPPG RG  G  G PG PG  GI G  G PG  G PG  G PG  G  GP G PG +G  
Sbjct: 69  GPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTK 128

Query: 87  GAKGEPGPMGIPGVKGQPGLPGPPG------------LPGP-GFAGPPGPPGPVGLPGEI 133
           G +G PG  G PG++G PG PG PG            LPGP G  G PGPPG  GLPG  
Sbjct: 129 GERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPT 188

Query: 134 GIRGPKGDPGPDGPSGPPGPPGKPGRPGTI-------------QGLEG------------ 168
           GI GP G PGP G  GPPGPPG PG  G +             QGL+G            
Sbjct: 189 GIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQK 248

Query: 169 ---SADFLCPTNCPPGMKGPPGLQGVK-------GHAGKRGILGDPGHQGKPGPKGDVGA 218
                +F       PG +GPPG  G++       G  G++G  G+PG +GKPG  G+ G 
Sbjct: 249 RPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQ 308

Query: 219 SGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATG-PPGEEGPRGPPGRAG 277
            G  G+PG PG  G  G  G  G KG+TGP G  G+V     TG   GE+G  G PG  G
Sbjct: 309 PGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPG 368

Query: 278 EKGDEGSPGIRGPQGITGPKGAT----------------------------GPPGINGKD 309
           EKG+ G PGI+GP G+ GP GA                             GPPG++G+ 
Sbjct: 369 EKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQP 428

Query: 310 GTPGTPGMKGSA-------------GQAGQPGSPGHQGLAGVPGQPGTKG-------GPG 349
           G PG PG  G A             G  G PGSPG +GL G  G  G KG       G G
Sbjct: 429 GAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTG 488

Query: 350 DQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPG--------- 400
             G PG  GLPG  GPPG  G PG +GE G  G  G KG  G  G  G PG         
Sbjct: 489 ISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPG 548

Query: 401 ----PQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGP------------RGKVGDP 444
                 G +G KGE G PG PG  GLPG  G  G PG  GP            RG  G+P
Sbjct: 549 DILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNP 608

Query: 445 GVAGLPGEKGEKGES--GEPGPKGQQGVR------GEPGYPGPSGD-------AGAPGVQ 489
           G+ GLPG  G  G    G PGP G++G++      G+PG PGP GD        G PG+ 
Sbjct: 609 GLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLP 668

Query: 490 GYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREAL 549
           G PG  G  GL G+ G+PGQPG  G+ G    +  I  + L           +     A 
Sbjct: 669 GNPGRDGDVGLPGDPGLPGQPGLPGIPGSKG-EPGIPGIGLPGPPGPKGFPGIPGPPGAP 727

Query: 550 GAVGMMGPPGPPGPPGYPGKQGPHGH-----PGPRGVPGIVGAV---------------- 588
           G  G +G  GPPGPPG+PG +G  G      PGP G+PG  GA+                
Sbjct: 728 GTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPG 787

Query: 589 --------GQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPG-QAINGKDGD 639
                   G  G+ GP G+ G  G PG  G G  G PGPPGIPG  G+PG   I G+ GD
Sbjct: 788 RTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGD 847

Query: 640 RGS-----PGAPGEAGRPGL---PGPVGLPGFCEPAACLGASAYASAR 679
            G      PG PGE G PG+   PGP+G PG        GAS +   +
Sbjct: 848 PGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTK 895



 Score =  475 bits (1222), Expect = e-134
 Identities = 303/728 (41%), Positives = 357/728 (49%), Gaps = 123/728 (16%)

Query: 25  IRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDG 84
           I+G  GERG PG  G PG+PG          PG  GPPGP+G+ G  G  GP        
Sbjct: 43  IKGEKGERGFPGLEGHPGLPGF---------PGPEGPPGPRGQKGDDGIPGP-------- 85

Query: 85  LTGAKGEPGPMGIPGVKGQPGLPGPPGLPG-PGFAGPPGP---PGPVGLPGEIGIRGPKG 140
                  PGP GI G  G PG PG PGLPG PG  G PGP   PG  G  GE G  G  G
Sbjct: 86  -------PGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPG 138

Query: 141 DPGPDGPSGPPGPPGKPGRPGTI-----QGLEGSADFLCPTNCPPGMKGPPGLQGVKGHA 195
            PG  GP GPPG PG  G PG+I      G +G+  +  P     G+ GP G+ G  G  
Sbjct: 139 FPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGI-QGLPGPTGIPGPIGPP 197

Query: 196 GKRGILGDPGHQGKPGPKGDVGAS--------GEQGIPGPPGPQGIRGYPGMAGPKGETG 247
           G  G++G PG  G PGPKG++G +        GEQG+ GPPGP G         P     
Sbjct: 198 GPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPG--QISEQKRPIDVEF 255

Query: 248 PHGYKGMVGAIGATGPPGEEGPRGPP-GRAGEKGDEGSPGIRGPQGITGPKGATGPPGIN 306
             G +G+ G  G  GPPG  GP GPP G  GEKG++G PG RG  G  G  G  G PG+ 
Sbjct: 256 QKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP 315

Query: 307 GKDGTPGTPGMKGSAGQAGQPGSP-------------------GHQGLAGVPGQPGTKGG 347
           G  G PG PG  G  GQ G  G P                   G+ GL G+PG+ G +G 
Sbjct: 316 GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGF 375

Query: 348 PGDQGEPGPQGLPGFS--GPPGKEGEPGPRGEIGPQG-----IMGQKGDQGERGPVGQPG 400
           PG QG PG  G PG +  GPPG  G PG RG+ G +G     I G  G  G+ G  G PG
Sbjct: 376 PGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPG 435

Query: 401 PQGRQGP----------KGEQGPPGIPGPQGL---PGVKGDKGS-------------PGK 434
           P G  GP           G  GPPG PG +GL    GVKGDKG              PG+
Sbjct: 436 PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495

Query: 435 TGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPG-VQGYPG 493
            G  G  G PG  G PG+KGEKG++G  GPKG  G+ G PG PG  G  G PG +  +PG
Sbjct: 496 PGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG 555

Query: 494 PPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKR------- 546
             G +G  G+ G PG PG  G  G+D          L   + +   +    +R       
Sbjct: 556 MKGDKGELGSPGAPGLPGLPGTPGQDGLP------GLPGPKGEPGGITFKGERGPPGNPG 609

Query: 547 --EALGAVGMMGPP--GPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQ-IGNTGPKGKRG 601
                G +G MGPP  GPPGP G  G QG  G+PG  G+PG  G  GQ I   G  G  G
Sbjct: 610 LPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669

Query: 602 EKGDPGEVG-RGHPGMPGPPGIPGLPGR------PGQAINGKDGDRGSPGAPGEAGRPGL 654
             G  G+VG  G PG+PG PG+PG+PG       PG  + G  G +G PG PG  G PG 
Sbjct: 670 NPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGT 729

Query: 655 PGPVGLPG 662
           PG +GL G
Sbjct: 730 PGRIGLEG 737



 Score =  471 bits (1211), Expect = e-132
 Identities = 285/638 (44%), Positives = 323/638 (50%), Gaps = 111/638 (17%)

Query: 25   IRGPPGERGPPG---------PPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDG 75
            + GPPGERG PG         PPG PG+PG  G  G  G  G+ G  GP G PG  G  G
Sbjct: 855  VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPG 914

Query: 76   PDGKPGI---DGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGE 132
              G PG+   DGL G  G PGP G  G KG+PGLPGPPG   P   G  G  G  GLPG 
Sbjct: 915  RSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGI 974

Query: 133  IGIRGPK------GDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGP- 185
             G+ GPK      GDPG  G SG PG PG PG  G   GL G    +     PPG+KG  
Sbjct: 975  PGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN-PGLPGQPGLI----GPPGLKGTI 1029

Query: 186  -----PGLQGVKGHAGKRGILGDPGHQGKPGPKGDVG-----ASGEQGIPGPPGPQGIRG 235
                 PG QGV+G  G  G+ G PG  G PG KGD G     + G  G+PGP G  G+ G
Sbjct: 1030 GDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPG 1089

Query: 236  YPGMAGPKGETGPHGYKGMVGAIGATGP------PGEEGPRGPPGRAGEKGDEGSPGIRG 289
            YPG  G KG  G  G  G+ G  GA G       PG  GP GP G +G  G+ G PG  G
Sbjct: 1090 YPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPG 1149

Query: 290  PQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQP--GSPGHQGL---------AGV 338
            P G  G  G  GPPG  GK G  G PG  G  G+ GQP  G+PG  GL          G+
Sbjct: 1150 PVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGL 1209

Query: 339  PGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEP-----GPRGEIGPQGIMGQKGDQGER 393
            PG PG  G PG +GEPG  G PG  GPPG  G P     GP+G  GPQG  G+ G QG  
Sbjct: 1210 PGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLP 1269

Query: 394  GPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGD------KGSPGKTGPRGKVGDPGVA 447
            GP G PG  G  G KGE+G PG PG  GLPG+KGD      +G+PG+ G  G  GDPG+ 
Sbjct: 1270 GPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLP 1329

Query: 448  GLPGEKGEKGESGEP---GPKGQQGV---RGEPGYPGPSGDA-------------GAPGV 488
            G+PG  G KG SG P   GP+G+ G+    G PG PGPSG +             G PG+
Sbjct: 1330 GVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGL 1389

Query: 489  QGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREA 548
            +G PGP GP+GL G  G PG PGR G+ G D                             
Sbjct: 1390 KGLPGPQGPQGLPGPTGPPGDPGRNGLPGFD----------------------------- 1420

Query: 549  LGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVG 586
             GA G  G PG PG PG  G  GP G  G +G PG  G
Sbjct: 1421 -GAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1457



 Score =  424 bits (1091), Expect = e-118
 Identities = 257/572 (44%), Positives = 293/572 (51%), Gaps = 87/572 (15%)

Query: 26   RGPPGERGPPGPPGPPGVPG---------SDGIDGDNGPPGKAGPPGPKGEPGKAGPDGP 76
            +G  G  GPPGPPGP G+PG          DG+ G  G PG  G  G KGEPG  GP GP
Sbjct: 895  KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGP 954

Query: 77   DGKPGIDGLTGAKGEPGPMGIPGV---KGQPGLPGPPGLPG----PGFAGPPGPPGPVGL 129
               P + G  G KGEPG  GIPGV   KG  GLPG PG PG    PG  GPPGP G  GL
Sbjct: 955  MD-PNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGL 1013

Query: 130  PGEIGIRGPKG---------DPGPDGPSGPPGPPGKPGRPGTIQGLEGSADF-----LCP 175
            PG+ G+ GP G          PGP G  GPPGP G PG+PG+  GL G         +  
Sbjct: 1014 PGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGS-PGLPGQKGDKGDPGISS 1072

Query: 176  TNCP--PGMKGPPGLQGVKGHAGKRGILGDPG---------------------HQGKPGP 212
               P  PG KG PGL G  G+ G +G +GDPG                       G PGP
Sbjct: 1073 IGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGP 1132

Query: 213  KGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEG---- 268
            KG  G  G  G+PG PGP G  G+PG  GP GE G  G  G+ G  G  G PG+ G    
Sbjct: 1133 KGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNP 1192

Query: 269  -PRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGP---PGINGKDGTPGTPGM-----KG 319
             P G PG +G+KGD G PGI G  G+ GPKG  G    PG+ G  G PG+PG      KG
Sbjct: 1193 GPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKG 1252

Query: 320  SAGQAGQPGSPGHQGLAGV---PGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRG 376
            + G  G PG PG QGL G    PG PG  G  G++G PG  GLPG  G  G +G PG +G
Sbjct: 1253 NPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQG 1312

Query: 377  EIGPQGIMGQKGDQGERGPVGQPG---PQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSP- 432
              G  G+ G KGD G  G  G PG   P G  G  G +G PG+ GP G PG+ G  G   
Sbjct: 1313 NPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSI 1372

Query: 433  ---GKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSG---DAGA- 485
               G  GP G  G PG+ GLPG +G +G  G  GP G  G  G PG+ G  G   D G  
Sbjct: 1373 IIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLP 1432

Query: 486  --PGVQGYPGPPGPRGLAGNRGVPGQPGRQGV 515
              PG +G  GPPGP GL   +G PG PG   V
Sbjct: 1433 GQPGTRGLDGPPGPDGL---QGPPGPPGTSSV 1461



 Score =  376 bits (965), Expect = e-104
 Identities = 244/596 (40%), Positives = 291/596 (48%), Gaps = 119/596 (19%)

Query: 181 GMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGM- 239
           G+KG  G +G  G  G  G+ G PG +G PGP+G     G+ GIPGPPGP+GIRG PG+ 
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQ---KGDDGIPGPPGPKGIRGPPGLP 98

Query: 240 -----------------AGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDE 282
                             GP+G  G +G KG  G  G+ G PG +GP GPPG  G KG+ 
Sbjct: 99  GFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEP 158

Query: 283 GS------------------PGIR---GPQGITGPKGATGPPGINGKDGTPGTPGMKGSA 321
           GS                  PGI+   GP GI GP G  GPPG+ G  G PG PG KG+ 
Sbjct: 159 GSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNM 218

Query: 322 GQ--AGQPGSPGHQGLAGVPGQP----------------GTKGGPGDQGEPGPQGLPGFS 363
           G    G  G  G QGL G PG P                G +G PGD+G PGP G+ G  
Sbjct: 219 GLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPP 278

Query: 364 GPP-------GKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGI 416
           GPP       G++GEPG RG+ G  G  GQ G  G  G  G PG  GR G KG++G  G 
Sbjct: 279 GPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGP 338

Query: 417 PGPQGLP----------GVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGES------- 459
           PGP GL           G KG+ G PG  G +G+ G PG+ G PG  G  G +       
Sbjct: 339 PGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGP 398

Query: 460 -GEPGPKGQQGVRGEPG--YPGPSGDAGAPGVQGYPGPPGPRG----------LAGNRGV 506
            G PG +GQ+G  G PG   PGP G  G PG  G PGPPGP G            G  G 
Sbjct: 399 PGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGP 458

Query: 507 PGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGY 566
           PG PG +G++G         D     +        +S      G  G+ GPPG  G PG 
Sbjct: 459 PGSPGDKGLQGEQGVKGDKGDTCFNCI-----GTGISGPPGQPGLPGLPGPPGSLGFPGQ 513

Query: 567 PGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGE-------KGDPGEVGR----GHPG 615
            G++G  G  GP+G+PGI GA G  G  G KG+ G+       KGD GE+G     G PG
Sbjct: 514 KGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573

Query: 616 MPGPPGIPGLPGRPGQ-----AINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEP 666
           +PG PG  GLPG PG       I  K G+RG PG PG  G PG  GP+G PGF  P
Sbjct: 574 LPGTPGQDGLPGLPGPKGEPGGITFK-GERGPPGNPGLPGLPGNIGPMGPPGFGPP 628



 Score =  365 bits (936), Expect = e-100
 Identities = 236/598 (39%), Positives = 283/598 (47%), Gaps = 123/598 (20%)

Query: 178 CPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYP 237
           C PG K      G+KG  G+RG  G  GH G PG        G +G PGP G +G  G P
Sbjct: 32  CSPGSKCD--CSGIKGEKGERGFPGLEGHPGLPG------FPGPEGPPGPRGQKGDDGIP 83

Query: 238 GMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPK 297
           G  GPKG  GP G  G  G  G  G PG +G  GP         +G PG  G +G  G  
Sbjct: 84  GPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGP---------QGIPGCNGTKGERGFP 134

Query: 298 GATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEP--- 354
           G+ G PG+ G  G PG PGMKG  G       PG +G  G PG PG +G PG  G P   
Sbjct: 135 GSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPI 194

Query: 355 GPQGLPGFSGPPGKEGEPGPRGEIGP--QGIMGQKGDQGERGPVGQP------------- 399
           GP G PG  GPPG  G PGP+G +G   QG  G+KG+QG +GP G P             
Sbjct: 195 GPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVE 254

Query: 400 ---GPQGRQGPKGEQGPPGIPGPQGLP----GVKGDKGSPGKTGPRGKVGD---PGVAGL 449
              G QG  G +G  GPPGI GP G P    G KG++G PGK G  GK G+   PG+ GL
Sbjct: 255 FQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGL 314

Query: 450 P------------GEKGEKGESGEPGPK-------------GQQGVRGEPGYPGPSGDAG 484
           P            GEKG+KG++G PGP              G++G  G PG PG  G+ G
Sbjct: 315 PGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERG 374

Query: 485 APGVQGYPGPPGPRGLA--GNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAV 542
            PG+QG PG PGP G A  G  G PG PG +G +G    D+    +++           +
Sbjct: 375 FPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKG----DEGPPGISIP------GPPGL 424

Query: 543 SAKREALGAVGMMGP-------------PGPPGPPGYPGKQGPHGH-------------- 575
             +  A G  G  GP             PGPPGPPG PG +G  G               
Sbjct: 425 DGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNC 484

Query: 576 -----PGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-RGHPGMPGPPGIPGLPGRP 629
                 GP G PG+ G  G  G+ G  G++GEKG  G  G +G PG+PG PG PG PG  
Sbjct: 485 IGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSK 544

Query: 630 GQ--------AINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASAR 679
           G+         + G  G+ GSPGAPG  G PG PG  GLPG   P    G   +   R
Sbjct: 545 GEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGER 602



 Score =  300 bits (767), Expect = 4e-81
 Identities = 183/446 (41%), Positives = 217/446 (48%), Gaps = 68/446 (15%)

Query: 274 GRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQ 333
           G  GEKG+ G PG+ G  G+ G  G  GPPG  G+ G  G PG  G  G  G PG PG  
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP 101

Query: 334 GLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGER 393
           G  G+PG PG  G PG QG PG  G  G  G PG  G PG +G  GP GI G KG+ G  
Sbjct: 102 GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSI 161

Query: 394 GPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPG-------- 445
                PGP+G  G  G  G  G+PGP G+PG  G  G PG  GP G  G PG        
Sbjct: 162 IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLN 221

Query: 446 VAGLPGEKGEKGESGEPGPKGQ----------QGVRGEPGYPGPSGDAGAPGVQGYPGPP 495
             G  GEKGE+G  G PGP GQ          +  +G+ G PG  G  G PG++G PGPP
Sbjct: 222 FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPP 281

Query: 496 GPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMM 555
           G  G  G +G  G+PG++G  G+D                         +    G  G+ 
Sbjct: 282 G--GEKGEKGEQGEPGKRGKPGKD------------------------GENGQPGIPGLP 315

Query: 556 GPPGPPGPPGYPGKQGPHGHPGPRGVPGIV----------GAVGQIGNTGPKGKRGEKGD 605
           G PG PG PG  G++G  G  GP G PG+V          G  G IG  G  G++GE+G 
Sbjct: 316 GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGF 375

Query: 606 PGEVGRGHPGMPGPPGI-----PGLPGRPGQAINGKDGDRGSPG--APGEAGRPGLPGPV 658
           PG   +G PG+PGPPG      PG PG PG+   G+ GD G PG   PG  G  G PG  
Sbjct: 376 PGI--QGPPGLPGPPGAAVMGPPGPPGFPGE--RGQKGDEGPPGISIPGPPGLDGQPGAP 431

Query: 659 GLPGFCEPAACLGASAYASARLTEPG 684
           GLPG   P    G     S  + EPG
Sbjct: 432 GLPG---PPGPAGPHIPPSDEICEPG 454



 Score =  185 bits (469), Expect = 1e-46
 Identities = 110/243 (45%), Positives = 130/243 (53%), Gaps = 44/243 (18%)

Query: 21   ALAQIRGPPGERGP---------PGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKA 71
            AL   +G PG +GP         PGP GPPG+PG+ GI G+ G PG+ G PG  G  G  
Sbjct: 1246 ALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQ 1305

Query: 72   GPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPG 131
            GP G  G PG  GL G KG+P   G+PGV G PG+ GP G+PG   AGP G PG +G P 
Sbjct: 1306 GPPGLQGNPGRPGLNGMKGDP---GLPGVPGFPGMKGPSGVPGS--AGPEGEPGLIGPP- 1359

Query: 132  EIGIRGPKGDPGPDGPS----GPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPG 187
                 GP G PGP G S    G  GPPG PG+PG ++GL             PG +GP G
Sbjct: 1360 -----GPPGLPGPSGQSIIIKGDAGPPGIPGQPG-LKGL-------------PGPQGPQG 1400

Query: 188  LQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETG 247
            L G  G  G      DPG  G PG  G  G  G+ G+PG PG +G+ G PG  G +G  G
Sbjct: 1401 LPGPTGPPG------DPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPG 1454

Query: 248  PHG 250
            P G
Sbjct: 1455 PPG 1457



 Score =  130 bits (326), Expect = 5e-30
 Identities = 91/247 (36%), Positives = 103/247 (41%), Gaps = 70/247 (28%)

Query: 462 PGPK----GQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEG 517
           PG K    G +G +GE G+PG  G  G PG  G  GPPGPRG  G+ G+PG PG +    
Sbjct: 34  PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPK---- 89

Query: 518 RDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGH-- 575
                                              G+ GPPG PG PG PG  G  GH  
Sbjct: 90  -----------------------------------GIRGPPGLPGFPGTPGLPGMPGHDG 114

Query: 576 -PGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAIN 634
            PGP+G+PG           G KG+RG  G PG  G   P  PGPPGIPG+ G PG  I 
Sbjct: 115 APGPQGIPGC---------NGTKGERGFPGSPGFPGLQGP--PGPPGIPGMKGEPGSIIM 163

Query: 635 ----GKDGDRGSPGAPGEAGRPGL---------PGPVGLPGFCEPAACLGASAYASARLT 681
               G  G+ G PG PG  G PG          PGP GL G   P    G          
Sbjct: 164 SSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQ 223

Query: 682 EPGSIKG 688
            P   KG
Sbjct: 224 GPKGEKG 230


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  545 bits (1404), Expect = e-155
 Identities = 328/732 (44%), Positives = 371/732 (50%), Gaps = 79/732 (10%)

Query: 26   RGPPGERGPPGPPGPPGVPGSDGIDGDNGPPG------------------KAGPPGPKGE 67
            RG PGERG PG PGP G  G+DG  G  GPPG                  +AGP GP+G 
Sbjct: 304  RGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGS 363

Query: 68   ------------PGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP 115
                        PG AG  GP G PG DG  GAKG  G  GI G  G PG  GP G  GP
Sbjct: 364  EGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGP 423

Query: 116  GFAGPPGP---PGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADF 172
            G  GPPGP    G  G PG  G  G KG+PGP G  GPPGP G+ G+ G  +G  G    
Sbjct: 424  G--GPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGA-RGEPG---- 476

Query: 173  LCPTNC--PPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGP--- 227
              PT    PPG +G PG +G  G  G  G  G  G +G PGP G  G+ GE G PG    
Sbjct: 477  --PTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGL 534

Query: 228  PGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGI 287
            PG +G+ G PG  GP G+TGP G  G  G  G  GPPG  G  G  G  G KG  G PG 
Sbjct: 535  PGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGK 594

Query: 288  RGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQ---PGSPGHQGLAGVPGQPGT 344
             G +G+ GP GA GP G +G+ G  G PG  G AG+ G+    GSPG QGL G  G PG 
Sbjct: 595  AGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGE 654

Query: 345  KGGPGDQGEPGPQGLPGFSGP------PGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQ 398
             G PG+QG PG  G PG SG       PG+ G  GP G  GP+G  G  G+ G +G  G 
Sbjct: 655  AGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGA 714

Query: 399  PGPQGRQGPKGEQGPPGIPGPQGLPGVKGDK---------GSPGKTGPR---GKVGDPGV 446
            PG  G QG  G QG PG  G  GLPG KGD+         GSPGK G R   G +G PG 
Sbjct: 715  PGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGP 774

Query: 447  AGLPGEKGEKGESGEPGPKGQQGV---RGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGN 503
            AG PG+KGE G SG  GP G +G    RGEPG PGP+G AG PG  G PG  G  G AG 
Sbjct: 775  AGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGA 834

Query: 504  RGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGP 563
            +G  G PG  G  G      ++     K  +        +    A G VG  GP G  GP
Sbjct: 835  KGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGP 894

Query: 564  PGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-RGHPGMPGPPGI 622
            PG PG  G  G  GPRG  G  G  G++G  GP G  GEKG PG  G  G PG PGP GI
Sbjct: 895  PGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGI 954

Query: 623  PGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYA-----S 677
             G  G  G  + G+ G+RG PG PG +G PG  GP G  G   P   +G    A     S
Sbjct: 955  AGQRGVVG--LPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGES 1012

Query: 678  ARLTEPGSIKGP 689
             R   PG+   P
Sbjct: 1013 GREGAPGAEGSP 1024



 Score =  542 bits (1397), Expect = e-154
 Identities = 322/762 (42%), Positives = 375/762 (49%), Gaps = 121/762 (15%)

Query: 22   LAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPG 81
            +A   G PG RGP GP GP G PG  G  G+ G PG  G  G KGEPG  G  GP G  G
Sbjct: 405  IAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAG 464

Query: 82   IDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPG----------------PGFAGPPGPPG 125
             +G  GA+GEPGP G+PG  G+ G PG  G PG                PG AGP G PG
Sbjct: 465  EEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPG 524

Query: 126  PVGLPGEIGIRGPK------GDPGPDGPSGPPGPPGKPGRPGT-----IQGLEGSADFLC 174
              G PGE G+ G K      G PGPDG +GPPGP G+ GRPG       +G  G   F  
Sbjct: 525  EAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPG 584

Query: 175  PTNC--------------PP------------GMKGPPGLQGVKGHAGKRGILGDPGHQG 208
            P                 PP            G +GPPG  G  G  G++G  G PG QG
Sbjct: 585  PKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQG 644

Query: 209  KP---GPKGDVGASGEQGI------PGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIG 259
             P   GP G+ G  GEQG+      PGP G +G RG+PG  G +G  GP G +G  GA G
Sbjct: 645  LPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPG 704

Query: 260  ATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMK- 318
              G  G+ G  G PG  G  G +G PG RG  G+ GPKG  G  G  G DG+PG  G++ 
Sbjct: 705  NDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRG 764

Query: 319  -----GSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPG 373
                 G  G AG PG  G  G +G  G  G +G PGD+GEPGP G  GF+GPPG +G+PG
Sbjct: 765  LTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPG 824

Query: 374  PRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPG 433
             +GE G  G  G  G  G  GP G PGP G  G  G +G  G  GP G  G  G  G  G
Sbjct: 825  AKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVG 884

Query: 434  KTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQ---G 490
              GP G  G PG  G  G++G KG  GE GP G+ G  G PG PGP+G+ G+PG     G
Sbjct: 885  PPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAG 944

Query: 491  YPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALK--------------MLQEQ 536
             PG PGP+G+AG RGV G PG++G  G         +   +              M    
Sbjct: 945  APGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPG 1004

Query: 537  LAEVAVSAKRE----------------ALGAVGMMGPPGPPGPPGYPGKQGP-------- 572
            LA     + RE                A G  G  GP GPPG PG PG  GP        
Sbjct: 1005 LAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSG 1064

Query: 573  -HGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-------RGHPGMPGPPGIPG 624
              G  GP G  G VG VG  G  GP+G RG+KG+ GE G       RG  G+ GPPG PG
Sbjct: 1065 DRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPG 1124

Query: 625  LPGRPG-QAINGKDGDRGSP---GAPGEAGRPGLPGPVGLPG 662
             PG  G    +G  G RG P   GAPG+ G  GLPGP+G PG
Sbjct: 1125 SPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPG 1166



 Score =  531 bits (1367), Expect = e-150
 Identities = 317/707 (44%), Positives = 363/707 (51%), Gaps = 84/707 (11%)

Query: 25  IRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDG---PDGKPG 81
           + GP G+ GP GP GP G PG DGI G    PG  GPPGP G PG  G  G   P    G
Sbjct: 110 VEGPKGDTGPRGPRGPAGPPGRDGIPGQ---PGLPGPPGPPGPPGPPGLGGNFAPQLSYG 166

Query: 82  ID-GLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP-GFAGPPGPPGPVGLPGEIGIRGPK 139
            D   TG    PGPMG  G +   GLPGPPG PGP GF GPPG PG  G  G +G RGP 
Sbjct: 167 YDEKSTGGISVPGPMGPSGPR---GLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPP 223

Query: 140 GDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRG 199
           G PG +G  G  G PG+PG  G   G +G+           G+ G  GL G+KGH G  G
Sbjct: 224 GPPGKNGDDGEAGKPGRPGERGP-PGPQGAR----------GLPGTAGLPGMKGHRGFSG 272

Query: 200 ILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIG 259
           + G  G  G  GPKG+ G+ GE G PG  GP   RG PG  G  G  GP G +G  GA G
Sbjct: 273 LDGAKGDAGPAGPKGEPGSPGENGAPGQMGP---RGLPGERGRPGAPGPAGARGNDGATG 329

Query: 260 ATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKG 319
           A GPPG  GP GPPG  G  G +G  G +GP+G  GP+G  G PG  G  G  G  G  G
Sbjct: 330 AAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPG 389

Query: 320 SAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQ---GEPGPQGLPGFSGPPGKEGEPGPRG 376
           + GQ G  G+ G  G+AG PG PG +G  G Q   G PGP+G  G  G PG +G+ G +G
Sbjct: 390 ADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKG 449

Query: 377 EIGPQGIM---GQKGDQGERGPVGQPGPQGRQGPKGEQGPP---GIPGPQGLPGVK---G 427
           E GP G+    G  G++G+RG  G+PGP G  GP GE+G P   G PG  G+ G K   G
Sbjct: 450 EPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAG 509

Query: 428 DKGSPGKTGPRGKVGD---PGVAGLPGEKGEKGESGEPGPKGQ------QGVRGEPGYPG 478
           ++GSPG  GP+G  G+   PG AGLPG KG  G  G PGP G+       G  G PG PG
Sbjct: 510 ERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPG 569

Query: 479 PSGDAGAPGVQGYPGPPGPR---GLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQE 535
           P G  G  GV G+PGP G     G AG RGVPG PG  G  G+D                
Sbjct: 570 PPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKD---------------- 613

Query: 536 QLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTG 595
              E          G  G  G  GP G PG+ G  GP G PG  G PG  G  G +G  G
Sbjct: 614 --GEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPG 671

Query: 596 PKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRP--- 652
           P G RGE+G PGE  RG  G PGP G  G  G PG   +G  GD G+PGAPG  G P   
Sbjct: 672 PSGARGERGFPGE--RGVQGPPGPAGPRGANGAPGN--DGAKGDAGAPGAPGSQGAPGLQ 727

Query: 653 ---------GLPGPVGLPGFCEPAACLGASAYASAR-LTEPGSIKGP 689
                    GLPGP G  G   P    G+      R LT P    GP
Sbjct: 728 GMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGP 774



 Score =  508 bits (1307), Expect = e-144
 Identities = 298/691 (43%), Positives = 344/691 (49%), Gaps = 93/691 (13%)

Query: 26   RGPPGERGPPGPPGPPGVPGSDGIDGDNGPPG------KAGPPGPKGEPGKAGPDGPDGK 79
            +GP GERG PGP GP G PG  G  G+ G PG        G PGP G+ G  GP G DG+
Sbjct: 505  KGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGR 564

Query: 80   PGIDGLTGAKGEPGPMGIPGVKG---------QPGLPGPPGLPGP----GFAGPPGPPGP 126
            PG  G  GA+G+ G MG PG KG         + G+PGPPG  GP    G AG  GPPGP
Sbjct: 565  PGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGP 624

Query: 127  VGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNC-------- 178
             G  GE G +GP G PG  G  GP GPPG+ G+PG  QG+ G      P+          
Sbjct: 625  AGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGE-QGVPGDLGAPGPSGARGERGFPG 683

Query: 179  ------PPGMKGPPGLQGVKGHAGKRGILGDPGHQGK------------------PGPKG 214
                  PPG  GP G  G  G+ G +G  G PG  G                   PGPKG
Sbjct: 684  ERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKG 743

Query: 215  DVGASGEQGIPGPPGPQGIRGYPGMAGP---------KGETGPHGYKGMVGAIGATGPPG 265
            D G +G +G  G PG  G+RG  G  GP         KGE+GP G  G  GA GA G  G
Sbjct: 744  DRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRG 803

Query: 266  EEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPG------TPGMKG 319
            E GP GP G AG  G +G PG +G  G  G KG  GPPG  G  G PG       PG KG
Sbjct: 804  EPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKG 863

Query: 320  SAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIG 379
            + G AG PG+ G  G AG  G PG  G  G  G PGP G  G  GP G+ G  G  GE+G
Sbjct: 864  ARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVG 923

Query: 380  PQGI---MGQKGDQGERGPVGQPGPQGRQG------------PKGEQGPPGIPGPQGLPG 424
            P G     G+KG  G  GP G PG  G QG             +GE+G PG+PGP G PG
Sbjct: 924  PPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPG 983

Query: 425  VKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGE---SGEPGPKGQQGVRGEPGYPGPSG 481
             +G  G+ G+ GP G +G PG+AG PGE G +G     G PG  G  G +G+ G  GP+G
Sbjct: 984  KQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAG 1043

Query: 482  DAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVA 541
              GAPG  G PGP GP G +G+RG  G  G  G  G             +  + +  E  
Sbjct: 1044 PPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQG 1103

Query: 542  VSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQ------IGNTG 595
                +   G  G+ GPPGPPG PG  G  G  G  GPRG PG  GA G+       G  G
Sbjct: 1104 DRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIG 1163

Query: 596  PKGKRGEKGDPGEVGRGHPGMPGPPGIPGLP 626
            P G RG  GD G V  G PG PGPPG PG P
Sbjct: 1164 PPGPRGRTGDAGPV--GPPGPPGPPGPPGPP 1192



 Score =  419 bits (1077), Expect = e-117
 Identities = 252/574 (43%), Positives = 288/574 (50%), Gaps = 66/574 (11%)

Query: 26   RGPPGERGPPGPPGPPG------VPGSDGIDGDNGPPGK------------------AGP 61
            RG PGERG  GPPGP G       PG+DG  GD G PG                   AG 
Sbjct: 679  RGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGL 738

Query: 62   PGPKGEPGKAGPDGPDGKPGIDG---LTGAKGEPGPMGIPGVKGQPGLPGP--------- 109
            PGPKG+ G AGP G DG PG DG   LTG  G PGP G PG KG+ G  GP         
Sbjct: 739  PGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGA 798

Query: 110  ------PGLPGP-GFAGPPGP---PGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGR 159
                  PG PGP GFAGPPG    PG  G PG+ G +G  G PGP GP+GPPGP G  G 
Sbjct: 799  PGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGA 858

Query: 160  PGTIQGLEGSADFLCPTNCP--PGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVG 217
            PG  +G  GSA     T  P   G  GPPG  G  G  G  G  G  G +G  G  G  G
Sbjct: 859  PGA-KGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAG 917

Query: 218  ASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAG 277
              GE G PGPPGP G +G PG  GP G  G  G +G+ G  G  G PG+ G RG PG  G
Sbjct: 918  RPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPG 977

Query: 278  EKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAG 337
              G+ G  G  G  G  GP G  GPPG+ G  G  G  G  G+ G  G+ GSPG +G  G
Sbjct: 978  PSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRG 1037

Query: 338  VPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVG 397
              G  G  G PG  G PGP G  G SG  G+ G  GP G +GP G  G  G QG RG  G
Sbjct: 1038 ETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKG 1097

Query: 398  QPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKG 457
            + G QG +G KG +G  G+ GP G PG  G++G  G +GP G  G PG AG P   G+ G
Sbjct: 1098 ETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAP---GKDG 1154

Query: 458  ESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQ---- 513
             +G PGP G  G RG  G  GP    G PG  G PGPPGP     +     QP ++    
Sbjct: 1155 LNGLPGPIGPPGPRGRTGDAGP---VGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHD 1211

Query: 514  GVEGRDATDQHI-------VDVALKMLQEQLAEV 540
            G     A D ++       VD  LK L +Q+  +
Sbjct: 1212 GGRYYRADDANVVRDRDLEVDTTLKSLSQQIENI 1245



 Score =  314 bits (805), Expect = 2e-85
 Identities = 180/427 (42%), Positives = 213/427 (49%), Gaps = 41/427 (9%)

Query: 259 GATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMK 318
           GA  P GE  P  P G      D+ + G+ GP+G TGP+G  GP G  G+DG PG PG+ 
Sbjct: 83  GAEVPEGECCPVCPDGSESPT-DQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLP 141

Query: 319 GSAGQAGQPGSPGHQG-------------------LAGVPGQPGTKGGPGDQGEPGPQGL 359
           G  G  G PG PG  G                   + G  G  G +G PG  G PGPQ  
Sbjct: 142 GPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQ-- 199

Query: 360 PGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGP 419
            GF GPPG+ GEPG  G +GP+G  G  G  G+ G  G+PG  G +GP G QG  G+PG 
Sbjct: 200 -GFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGT 258

Query: 420 QGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGP 479
            GLPG+KG +G  G  G +G  G  G  G PG  GE G  G+ GP+G  G RG PG PGP
Sbjct: 259 AGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGP 318

Query: 480 SGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAE 539
           +G  G  G  G  GPPGP G AG  G PG  G +G  G                +     
Sbjct: 319 AGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGP------------RGSEGP 366

Query: 540 VAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGK 599
             V  +    G  G  GP G PG  G PG +G +G PG  G PG  GA G  G  GP G 
Sbjct: 367 QGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGP 426

Query: 600 RGEKGDPGEVG----RGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLP 655
            G KG+ GE G    +G  G  G PG  G+ G PG A  G++G RG+ G PG  G PG P
Sbjct: 427 PGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPA--GEEGKRGARGEPGPTGLPGPP 484

Query: 656 GPVGLPG 662
           G  G PG
Sbjct: 485 GERGGPG 491



 Score =  195 bits (495), Expect = 1e-49
 Identities = 118/279 (42%), Positives = 133/279 (47%), Gaps = 36/279 (12%)

Query: 2    AAATASPRSLLVLLQVVVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGP 61
            A A  +P    +  Q  V+ L   RG  G  G PGP G PG  G  G  G+ GPPG  GP
Sbjct: 943  AGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGP 1002

Query: 62   P---GPKGEPGKAGPDGPDGKPGIDGLTGAK---GEPGPMGIPGVKGQPGLPGPPGLPG- 114
            P   GP GE G+ G  G +G PG DG  GAK   GE GP G PG  G PG PGP G  G 
Sbjct: 1003 PGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGK 1062

Query: 115  PGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLC 174
             G  G  GP GP G  G +G RGP G  GP G  G  G  G        +G++G   F  
Sbjct: 1063 SGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGD-------RGIKGHRGF-- 1113

Query: 175  PTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIR 234
                  G++GPPG  G  G  G  G  G  G +G PG  G  G  G  G+PGP GP G R
Sbjct: 1114 -----SGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPR 1168

Query: 235  GYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPP 273
            G  G AGP               +G  GPPG  GP GPP
Sbjct: 1169 GRTGDAGP---------------VGPPGPPGPPGPPGPP 1192


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score =  543 bits (1399), Expect = e-154
 Identities = 327/770 (42%), Positives = 378/770 (49%), Gaps = 140/770 (18%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKA--GPDGPDGKPGIDG 84
            GPPG +G PG PGPPG PG+ G  G  GPPG  G PGPKGEPG A  GP GP G PG  G
Sbjct: 710  GPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG 769

Query: 85   LTGAKGE------------------PGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPG- 125
              G KG+                  PGP G  G  GQPG  GPPGLPG G  GPPGPPG 
Sbjct: 770  ALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI 829

Query: 126  --PVGLPGEIGIRGPKGDPGPDG--------------------PSGPPGPPGKPGRPGT- 162
              P+G PG  GI G KGDPGP G                    P GPPG PG PG+ G  
Sbjct: 830  PGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889

Query: 163  -IQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGE 221
               G +G    + P   PPG  G PG  GV G  G  G+ G PG    PGP G+ G+ GE
Sbjct: 890  GFPGTKGEMGMMGPPG-PPGPLGIPGRSGVPGLKGDDGLQGQPG---LPGPTGEKGSKGE 945

Query: 222  QGIPGPPGP--------QGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPP 273
             G+PGPPGP        +G +G PG+ G  G +GP GY+G+ G  G  G  G+ G  GPP
Sbjct: 946  PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPP 1005

Query: 274  GRAGEKGDEGSPGIRGPQGITG---------PKGATGPPGINGKDGTPGTPGMKGSAGQA 324
            G  G  G  G PG+ GP G+ G         P+G  GPPG +G  G PG+PG+ G  G  
Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065

Query: 325  GQPG-----------------------------SPGHQGLAGVPGQPGTKGGPG---DQG 352
            G PG                             S G  GL G+PG PG KG PG     G
Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG 1125

Query: 353  EPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQG 412
             PGP G  G SGPPG  G PG  G +G  G  GQ G  GE+G  GQ G  G  G KGE G
Sbjct: 1126 TPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG 1185

Query: 413  PPGI--PGPQGLPGVKGDKGS------PGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGP 464
             PG   PGP GLPG+ G KG       PG  G  G  G+PG  G PG +G  G  G PGP
Sbjct: 1186 QPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP 1245

Query: 465  KGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQH 524
               +G +G PG  GP G  G PG +G PG PG  G+ G +G PGQPG  G+ G       
Sbjct: 1246 -ALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPG------- 1297

Query: 525  IVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPG---PRGV 581
                    L+       +       G  GM G PG PG PG+PG +GP G PG   P G 
Sbjct: 1298 --------LKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGE 1349

Query: 582  PGIVGAVGQIGNTGPKGK----RGEKGDPGEVGR----------GHPGMPGPPGIPGLPG 627
            PG++G  G  G  GP G+    +G+ G PG  G+          G  G+PGP G PG PG
Sbjct: 1350 PGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPG 1409

Query: 628  RPG-QAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYA 676
            R G    +G  G +G PG PG+ G  GL GP G  G   P    G S+ A
Sbjct: 1410 RNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1459



 Score =  518 bits (1333), Expect = e-147
 Identities = 330/801 (41%), Positives = 392/801 (48%), Gaps = 157/801 (19%)

Query: 19   VLALAQIRGPPGERGPPGPPGPPGVPGSDGID------------------GDNGPPGKA- 59
            +L    ++G  GE G PG PG PG+PG+ G D                  G+ GPPG   
Sbjct: 550  ILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPG 609

Query: 60   ----------------GPPGPKGE---------PGKAGPDGPDG---------------- 78
                            GPPGP GE         PG+ G  GP G                
Sbjct: 610  LPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669

Query: 79   ------------------KPGIDGLTGAKGEPGPMGI-----PGVKGQPGLPGPPGLPG- 114
                              +PG+ G+ G+KGEPG  GI     PG KG PG+PGPPG PG 
Sbjct: 670  NPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGT 729

Query: 115  ------------PGFAGP--------PGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPP 154
                        PGF GP        PGPPGP GLPG  G  GPKGD G  GP GPPG  
Sbjct: 730  PGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRT 789

Query: 155  GKPGRPGT--IQGLEGSADFLCPTNCPP-GMKGPPGLQGVKGHAGKRGILGDPGHQGKPG 211
            G  G PG     G  G    + P   P  G++GPPG  G+ G  G+ G+ G PG +G PG
Sbjct: 790  GLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPG 849

Query: 212  PKG-DV-GASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGP 269
            P G DV G  GE+G PG PG  G  G PG  G  G+ G  G+ G  G +G  GPPG  GP
Sbjct: 850  PPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGP 909

Query: 270  RGPPGRAGEKGDEGSPGIRGPQGITGP---KGATGPPGINGKDGTPGTPGMKGSAGQAGQ 326
             G PGR+G  G +G  G++G  G+ GP   KG+ G PG+ G  G P  P + GS G+ G+
Sbjct: 910  LGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG-PMDPNLLGSKGEKGE 968

Query: 327  PGSP---------GHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGE 377
            PG P         G+QGL G PGQPG  G PG  G PGP+G PG  G PG  G PG +G 
Sbjct: 969  PGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGT 1028

Query: 378  IGPQGIMGQKGDQGERGP---VGQPGPQGRQGPKGEQGPPGIP--GPQGLPGVKGD---K 429
            IG  G  G +G +G  GP    GQPG  G  G KG++G PGI   G  GLPG KG+    
Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP 1088

Query: 430  GSPGKTGPRGKVGDPGVAGLPGEKGEKGE---------SGEPGPKGQQGVRGEPGYPGPS 480
            G PG  G +G VGDPG+ GLPG  G KG+          G PGPKG  G  G PG PG  
Sbjct: 1089 GYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEP 1148

Query: 481  GDAGAPGVQGYPGPPGPRGL---------AGNRGVPGQP--GRQGVEGRDATDQHIVDVA 529
            G  G  G  G PGPPG +G          AG +G PGQP  G  G  G         D  
Sbjct: 1149 GPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGG 1208

Query: 530  LKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGV---PGIVG 586
            L  +           +    G  G+ GPPGPPG PG P  +GP G+PGP+G    PG+ G
Sbjct: 1209 LPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQGPPGRPGLPG 1267

Query: 587  AVGQIGNTGPKGKRGEKGDPGEVG-RGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGA 645
              G  G  G  G +GEKG+PG+ G  G PG+ G  G PGL G PG+   G +G +G PG 
Sbjct: 1268 PEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRP--GLNGMKGDPGL 1325

Query: 646  PGEAGRPGLPGPVGLPGFCEP 666
            PG  G PG+ GP G+PG   P
Sbjct: 1326 PGVPGFPGMKGPSGVPGSAGP 1346



 Score =  509 bits (1312), Expect = e-144
 Identities = 336/807 (41%), Positives = 377/807 (46%), Gaps = 184/807 (22%)

Query: 27   GPPGERGP----------PGPPGPPGVPGSDGIDGDNG---------------------- 54
            GPPG  GP          PGPPGPPG PG  G+ G+ G                      
Sbjct: 435  GPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPG 494

Query: 55   ---------PPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMG-------IP 98
                     PPG  G PG KGE G+AG  GP G PGI G  GA G PG  G        P
Sbjct: 495  QPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFP 554

Query: 99   GVKGQ------PGLPGPPGLPG-PGFAGPPGPPGPVGLPGEI---GIRGPKGDPGPDG-- 146
            G+KG       PG PG PGLPG PG  G PG PGP G PG I   G RGP G+PG  G  
Sbjct: 555  GMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLP 614

Query: 147  ----PSGPPG--PPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGP-------------PG 187
                P GPPG  PPG  G  G IQG+ G+          PG+ GP             PG
Sbjct: 615  GNIGPMGPPGFGPPGPVGEKG-IQGVAGNPG-------QPGIPGPKGDPGQTITQPGKPG 666

Query: 188  LQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGP--PGPQGIRGYPGMAGPKGE 245
            L G  G  G  G+ GDPG  G+PG  G  G+ GE GIPG   PGP G +G+PG+ GP G 
Sbjct: 667  LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGA 726

Query: 246  TGPHGYKGMVGAIGATGPPGEEGPRGPPGRA--GEKGDEGSPGIRGPQGITGPKGATGPP 303
             G     G +G  G  GPPG  GP+G PG A  G  G  G PG +G  G  G +G  GPP
Sbjct: 727  PGT---PGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPP 783

Query: 304  GINGKDGTPGTPGMKGSAGQAGQPGS--------------PGHQGLAGVPGQPGTKGGPG 349
            G  G+ G  G PG KG  G  GQPG               PG  G+ G  GQPG  G PG
Sbjct: 784  GPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPG 843

Query: 350  DQGEPGPQGL--PGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGP 407
            ++G+PGP GL  PG  G  G  G PG  G IGP G  G  G  G  G  G  G  G  GP
Sbjct: 844  EKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP 903

Query: 408  KGEQGPPGIPGPQGLPGVKGDKGS------PGKTGPRGKVGDPGVAGLP--------GEK 453
             G  GP GIPG  G+PG+KGD G       PG TG +G  G+PG+ G P        G K
Sbjct: 904  PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSK 963

Query: 454  GEKGESGEP------GPKGQQGVRGEPGYPGPSGDAGAPGV------------------- 488
            GEKGE G P      GPKG QG+ G+PG PG SG  G PG                    
Sbjct: 964  GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPP 1023

Query: 489  --------QGYPGPPGPRGLAGNRGVPGQPGRQGVEGR--DATDQHIVDVALKMLQEQLA 538
                     G+PGP G  G  G  GVPGQPG  G+ G+  D  D  I  + L  L     
Sbjct: 1024 GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKG 1083

Query: 539  EVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKG 598
            E  +       G  G+ G  G PG PG PG  G  G PG  G PG  G  G  G +GP G
Sbjct: 1084 EPGLPGYP---GNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPG 1140

Query: 599  KRGEKGDPGEV-GRGHPGMPGPPGIPGLPGR------------PGQ---------AINGK 636
              G  G+PG V G GHPG PGPPG  G PG+            PGQ          + G 
Sbjct: 1141 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL 1200

Query: 637  DGDRGSPGAPGEAGRPGLPGPVGLPGF 663
             G +G  G PG  G PGLPGP G PGF
Sbjct: 1201 SGQKGDGGLPGIPGNPGLPGPKGEPGF 1227



 Score =  509 bits (1310), Expect = e-144
 Identities = 331/828 (39%), Positives = 386/828 (46%), Gaps = 176/828 (21%)

Query: 27  GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
           GPPG RG  G  G PG PG  GI G  G PG  G PG  G PG  G  GP G PG +G  
Sbjct: 69  GPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTK 128

Query: 87  GAKGEPGPMGIPGVKGQPGLPGPPG------------LPGP-GFAGPPGPPGPVGLPGEI 133
           G +G PG  G PG++G PG PG PG            LPGP G  G PGPPG  GLPG  
Sbjct: 129 GERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPT 188

Query: 134 GIRGPKGDPGPDGPSGPPGPPGKPGRPGTI-------------QGLEG------------ 168
           GI GP G PGP G  GPPGPPG PG  G +             QGL+G            
Sbjct: 189 GIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQK 248

Query: 169 ---SADFLCPTNCPPGMKGPPGLQGVK-------GHAGKRGILGDPGHQGKPGPKGDVGA 218
                +F       PG +GPPG  G++       G  G++G  G+PG +GKPG  G+ G 
Sbjct: 249 RPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQ 308

Query: 219 SGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATG-PPGEEGPRGPPGRAG 277
            G  G+PG PG  G  G  G  G KG+TGP G  G+V     TG   GE+G  G PG  G
Sbjct: 309 PGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPG 368

Query: 278 EKGDEGSPGIRGPQGITGPKGAT----------------------------GPPGINGKD 309
           EKG+ G PGI+GP G+ GP GA                             GPPG++G+ 
Sbjct: 369 EKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQP 428

Query: 310 GTPGTPGMKGSA-------------GQAGQPGSPGHQGLAGVPGQPGTKG-------GPG 349
           G PG PG  G A             G  G PGSPG +GL G  G  G KG       G G
Sbjct: 429 GAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTG 488

Query: 350 DQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPG--------- 400
             G PG  GLPG  GPPG  G PG +GE G  G  G KG  G  G  G PG         
Sbjct: 489 ISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPG 548

Query: 401 ----PQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGP------------RGKVGDP 444
                 G +G KGE G PG PG  GLPG  G  G PG  GP            RG  G+P
Sbjct: 549 DILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNP 608

Query: 445 GVAGLPGEKGEKGES--GEPGPKGQQGVR------GEPGYPGPSGD-------AGAPGVQ 489
           G+ GLPG  G  G    G PGP G++G++      G+PG PGP GD        G PG+ 
Sbjct: 609 GLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLP 668

Query: 490 GYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREAL 549
           G PG  G  GL G+ G+PGQPG  G+ G    +  I  + L           +     A 
Sbjct: 669 GNPGRDGDVGLPGDPGLPGQPGLPGIPGSKG-EPGIPGIGLPGPPGPKGFPGIPGPPGAP 727

Query: 550 GAVGMMGPPGPPGPPGYPGKQGPHGH-----PGPRGVPGIVGAV---------------- 588
           G  G +G  GPPGPPG+PG +G  G      PGP G+PG  GA+                
Sbjct: 728 GTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPG 787

Query: 589 --------GQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPG-QAINGKDGD 639
                   G  G+ GP G+ G  G PG  G G  G PGPPGIPG  G+PG   I G+ GD
Sbjct: 788 RTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGD 847

Query: 640 RGS-----PGAPGEAGRPGL---PGPVGLPGFCEPAACLGASAYASAR 679
            G      PG PGE G PG+   PGP+G PG        GAS +   +
Sbjct: 848 PGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTK 895



 Score =  479 bits (1232), Expect = e-135
 Identities = 286/690 (41%), Positives = 343/690 (49%), Gaps = 104/690 (15%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGD------NGPPGKAGPPG-----PKGEPGKAGPDG 75
            GP G+RG PGPPGPPG  G DG+ G       NG PG  GPPG      +G PG  G  G
Sbjct: 772  GPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPG 831

Query: 76   PDGKPGIDGLTGAKGEPGPMGI-----PGVKGQPGLPGPPGLPGP--------------- 115
            P G+PG+ G+ G KG+PGP G+     PG +G PG+PG PG  GP               
Sbjct: 832  PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGF 891

Query: 116  -------GFAGPPGPPGPVGLPGEIGIRGPKGD---------PGPDGPSGPPGPPGKPGR 159
                   G  GPPGPPGP+G+PG  G+ G KGD         PGP G  G  G PG PG 
Sbjct: 892  PGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGP 951

Query: 160  PGTIQ-GLEGSADFLCPTNCP--PGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDV 216
            PG +   L GS         P  PG+ GP G QG+ G  G+ G+ G PG  G PGPKG+ 
Sbjct: 952  PGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNP 1011

Query: 217  GASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRA 276
            G  G+ G+ GPPG +G  G  G  GP+G  GP G  G+ G  G+ G PG++G +G PG +
Sbjct: 1012 GLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGIS 1071

Query: 277  --------GEKGDEGSPGIRGPQGITGP------------KGATGPPGINGKDGTPGTPG 316
                    G KG+ G PG  G  GI G              GA G PG+ G  GTPG PG
Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131

Query: 317  MKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRG 376
             KG +G  G PG PG  G  G  G PG  G PG++G+PG  G+PG +G  G+ G+PG  G
Sbjct: 1132 PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG-FG 1190

Query: 377  EIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGE---------QGPPGIPG--------P 419
              GP G+ G  G +G+ G  G PG  G  GPKGE         QGPPG PG        P
Sbjct: 1191 NPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGP 1250

Query: 420  QGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPG---------PKGQQGV 470
            +G PG +G  G PG  GP G  G PG  G+ GEKG  G+ G PG         P G QG 
Sbjct: 1251 KGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGN 1310

Query: 471  RGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDA----TDQHIV 526
             G PG  G  GD G PGV G+PG  GP G+ G+ G  G+PG  G  G       + Q I+
Sbjct: 1311 PGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSII 1370

Query: 527  ---DVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPG 583
               D     +  Q     +   +   G  G  GPPG PG  G PG  G  G  G  G+PG
Sbjct: 1371 IKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPG 1430

Query: 584  IVGAVGQIGNTGPKGKRGEKGDPGEVGRGH 613
              G  G  G  GP G +G  G PG     H
Sbjct: 1431 QPGTRGLDGPPGPDGLQGPPGPPGTSSVAH 1460



 Score =  475 bits (1222), Expect = e-134
 Identities = 303/728 (41%), Positives = 357/728 (49%), Gaps = 123/728 (16%)

Query: 25  IRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDG 84
           I+G  GERG PG  G PG+PG          PG  GPPGP+G+ G  G  GP        
Sbjct: 43  IKGEKGERGFPGLEGHPGLPGF---------PGPEGPPGPRGQKGDDGIPGP-------- 85

Query: 85  LTGAKGEPGPMGIPGVKGQPGLPGPPGLPG-PGFAGPPGP---PGPVGLPGEIGIRGPKG 140
                  PGP GI G  G PG PG PGLPG PG  G PGP   PG  G  GE G  G  G
Sbjct: 86  -------PGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPG 138

Query: 141 DPGPDGPSGPPGPPGKPGRPGTI-----QGLEGSADFLCPTNCPPGMKGPPGLQGVKGHA 195
            PG  GP GPPG PG  G PG+I      G +G+  +  P     G+ GP G+ G  G  
Sbjct: 139 FPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGI-QGLPGPTGIPGPIGPP 197

Query: 196 GKRGILGDPGHQGKPGPKGDVGAS--------GEQGIPGPPGPQGIRGYPGMAGPKGETG 247
           G  G++G PG  G PGPKG++G +        GEQG+ GPPGP G         P     
Sbjct: 198 GPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPG--QISEQKRPIDVEF 255

Query: 248 PHGYKGMVGAIGATGPPGEEGPRGPP-GRAGEKGDEGSPGIRGPQGITGPKGATGPPGIN 306
             G +G+ G  G  GPPG  GP GPP G  GEKG++G PG RG  G  G  G  G PG+ 
Sbjct: 256 QKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP 315

Query: 307 GKDGTPGTPGMKGSAGQAGQPGSP-------------------GHQGLAGVPGQPGTKGG 347
           G  G PG PG  G  GQ G  G P                   G+ GL G+PG+ G +G 
Sbjct: 316 GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGF 375

Query: 348 PGDQGEPGPQGLPGFS--GPPGKEGEPGPRGEIGPQG-----IMGQKGDQGERGPVGQPG 400
           PG QG PG  G PG +  GPPG  G PG RG+ G +G     I G  G  G+ G  G PG
Sbjct: 376 PGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPG 435

Query: 401 PQGRQGP----------KGEQGPPGIPGPQGL---PGVKGDKGS-------------PGK 434
           P G  GP           G  GPPG PG +GL    GVKGDKG              PG+
Sbjct: 436 PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495

Query: 435 TGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPG-VQGYPG 493
            G  G  G PG  G PG+KGEKG++G  GPKG  G+ G PG PG  G  G PG +  +PG
Sbjct: 496 PGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG 555

Query: 494 PPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKR------- 546
             G +G  G+ G PG PG  G  G+D          L   + +   +    +R       
Sbjct: 556 MKGDKGELGSPGAPGLPGLPGTPGQDGLP------GLPGPKGEPGGITFKGERGPPGNPG 609

Query: 547 --EALGAVGMMGPP--GPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQ-IGNTGPKGKRG 601
                G +G MGPP  GPPGP G  G QG  G+PG  G+PG  G  GQ I   G  G  G
Sbjct: 610 LPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669

Query: 602 EKGDPGEVG-RGHPGMPGPPGIPGLPGR------PGQAINGKDGDRGSPGAPGEAGRPGL 654
             G  G+VG  G PG+PG PG+PG+PG       PG  + G  G +G PG PG  G PG 
Sbjct: 670 NPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGT 729

Query: 655 PGPVGLPG 662
           PG +GL G
Sbjct: 730 PGRIGLEG 737



 Score =  467 bits (1202), Expect = e-131
 Identities = 284/636 (44%), Positives = 325/636 (51%), Gaps = 110/636 (17%)

Query: 25   IRGPPGERGPPG---------PPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDG 75
            + GPPGERG PG         PPG PG+PG  G  G  G  G+ G  GP G PG  G  G
Sbjct: 855  VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPG 914

Query: 76   PDGKPGI---DGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGE 132
              G PG+   DGL G  G PGP G  G KG+PGLPGPPG   P   G  G  G  GLPG 
Sbjct: 915  RSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGI 974

Query: 133  IGIRGPK------GDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGP- 185
             G+ GPK      GDPG  G SG PG PG PG  G   GL G    +     PPG+KG  
Sbjct: 975  PGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN-PGLPGQPGLI----GPPGLKGTI 1029

Query: 186  -----PGLQGVKGHAGKRGILGDPGHQGKPGPKGDVG-----ASGEQGIPGPPGPQGIRG 235
                 PG QGV+G  G  G+ G PG  G PG KGD G     + G  G+PGP G  G+ G
Sbjct: 1030 GDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPG 1089

Query: 236  YPGMAGPKGETGPHGYKGMVGAIGATGP------PGEEGPRGPPGRAGEKGDEGSPGIRG 289
            YPG  G KG  G  G  G+ G  GA G       PG  GP GP G +G  G+ G PG  G
Sbjct: 1090 YPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPG 1149

Query: 290  PQGITGPKGATGPPGINGK---DGTPGTPGMKGSAGQA--GQPGSPGHQGLAGVPGQPGT 344
            P G  G  G  GPPG  GK   DG PG  G KG  GQ   G PG PG  GL+G  G  G 
Sbjct: 1150 PVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGL 1209

Query: 345  KGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGR 404
             G PG+ G PGP+G PGF G PG +G PGP G  GP  + G KG+ G +GP G+PG  G 
Sbjct: 1210 PGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP-ALEGPKGNPGPQGPPGRPGLPGP 1268

Query: 405  QGP---------KGEQGPPGIPGPQGLPGVKGD------KGSPGKTGPRGKVGDPGVAGL 449
            +GP         KGE+G PG PG  GLPG+KGD      +G+PG+ G  G  GDPG+ G+
Sbjct: 1269 EGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGV 1328

Query: 450  PGEKGEKGESGEP---GPKGQQGV---RGEPGYPGPSGDA-------------GAPGVQG 490
            PG  G KG SG P   GP+G+ G+    G PG PGPSG +             G PG++G
Sbjct: 1329 PGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKG 1388

Query: 491  YPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALG 550
             PGP GP+GL G  G PG PGR G+ G D                              G
Sbjct: 1389 LPGPQGPQGLPGPTGPPGDPGRNGLPGFD------------------------------G 1418

Query: 551  AVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVG 586
            A G  G PG PG PG  G  GP G  G +G PG  G
Sbjct: 1419 AGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1454



 Score =  376 bits (965), Expect = e-104
 Identities = 244/596 (40%), Positives = 291/596 (48%), Gaps = 119/596 (19%)

Query: 181 GMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGM- 239
           G+KG  G +G  G  G  G+ G PG +G PGP+G     G+ GIPGPPGP+GIRG PG+ 
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQ---KGDDGIPGPPGPKGIRGPPGLP 98

Query: 240 -----------------AGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDE 282
                             GP+G  G +G KG  G  G+ G PG +GP GPPG  G KG+ 
Sbjct: 99  GFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEP 158

Query: 283 GS------------------PGIR---GPQGITGPKGATGPPGINGKDGTPGTPGMKGSA 321
           GS                  PGI+   GP GI GP G  GPPG+ G  G PG PG KG+ 
Sbjct: 159 GSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNM 218

Query: 322 GQ--AGQPGSPGHQGLAGVPGQP----------------GTKGGPGDQGEPGPQGLPGFS 363
           G    G  G  G QGL G PG P                G +G PGD+G PGP G+ G  
Sbjct: 219 GLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPP 278

Query: 364 GPP-------GKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGI 416
           GPP       G++GEPG RG+ G  G  GQ G  G  G  G PG  GR G KG++G  G 
Sbjct: 279 GPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGP 338

Query: 417 PGPQGLP----------GVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGES------- 459
           PGP GL           G KG+ G PG  G +G+ G PG+ G PG  G  G +       
Sbjct: 339 PGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGP 398

Query: 460 -GEPGPKGQQGVRGEPG--YPGPSGDAGAPGVQGYPGPPGPRG----------LAGNRGV 506
            G PG +GQ+G  G PG   PGP G  G PG  G PGPPGP G            G  G 
Sbjct: 399 PGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGP 458

Query: 507 PGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGY 566
           PG PG +G++G         D     +        +S      G  G+ GPPG  G PG 
Sbjct: 459 PGSPGDKGLQGEQGVKGDKGDTCFNCI-----GTGISGPPGQPGLPGLPGPPGSLGFPGQ 513

Query: 567 PGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGE-------KGDPGEVGR----GHPG 615
            G++G  G  GP+G+PGI GA G  G  G KG+ G+       KGD GE+G     G PG
Sbjct: 514 KGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573

Query: 616 MPGPPGIPGLPGRPGQ-----AINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEP 666
           +PG PG  GLPG PG       I  K G+RG PG PG  G PG  GP+G PGF  P
Sbjct: 574 LPGTPGQDGLPGLPGPKGEPGGITFK-GERGPPGNPGLPGLPGNIGPMGPPGFGPP 628



 Score =  365 bits (936), Expect = e-100
 Identities = 236/598 (39%), Positives = 283/598 (47%), Gaps = 123/598 (20%)

Query: 178 CPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYP 237
           C PG K      G+KG  G+RG  G  GH G PG        G +G PGP G +G  G P
Sbjct: 32  CSPGSKCD--CSGIKGEKGERGFPGLEGHPGLPG------FPGPEGPPGPRGQKGDDGIP 83

Query: 238 GMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPK 297
           G  GPKG  GP G  G  G  G  G PG +G  GP         +G PG  G +G  G  
Sbjct: 84  GPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGP---------QGIPGCNGTKGERGFP 134

Query: 298 GATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEP--- 354
           G+ G PG+ G  G PG PGMKG  G       PG +G  G PG PG +G PG  G P   
Sbjct: 135 GSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPI 194

Query: 355 GPQGLPGFSGPPGKEGEPGPRGEIGP--QGIMGQKGDQGERGPVGQP------------- 399
           GP G PG  GPPG  G PGP+G +G   QG  G+KG+QG +GP G P             
Sbjct: 195 GPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVE 254

Query: 400 ---GPQGRQGPKGEQGPPGIPGPQGLP----GVKGDKGSPGKTGPRGKVGD---PGVAGL 449
              G QG  G +G  GPPGI GP G P    G KG++G PGK G  GK G+   PG+ GL
Sbjct: 255 FQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGL 314

Query: 450 P------------GEKGEKGESGEPGPK-------------GQQGVRGEPGYPGPSGDAG 484
           P            GEKG+KG++G PGP              G++G  G PG PG  G+ G
Sbjct: 315 PGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERG 374

Query: 485 APGVQGYPGPPGPRGLA--GNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAV 542
            PG+QG PG PGP G A  G  G PG PG +G +G    D+    +++           +
Sbjct: 375 FPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKG----DEGPPGISIP------GPPGL 424

Query: 543 SAKREALGAVGMMGP-------------PGPPGPPGYPGKQGPHGH-------------- 575
             +  A G  G  GP             PGPPGPPG PG +G  G               
Sbjct: 425 DGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNC 484

Query: 576 -----PGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-RGHPGMPGPPGIPGLPGRP 629
                 GP G PG+ G  G  G+ G  G++GEKG  G  G +G PG+PG PG PG PG  
Sbjct: 485 IGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSK 544

Query: 630 GQ--------AINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASAR 679
           G+         + G  G+ GSPGAPG  G PG PG  GLPG   P    G   +   R
Sbjct: 545 GEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGER 602



 Score =  300 bits (767), Expect = 4e-81
 Identities = 183/446 (41%), Positives = 217/446 (48%), Gaps = 68/446 (15%)

Query: 274 GRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQ 333
           G  GEKG+ G PG+ G  G+ G  G  GPPG  G+ G  G PG  G  G  G PG PG  
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP 101

Query: 334 GLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGER 393
           G  G+PG PG  G PG QG PG  G  G  G PG  G PG +G  GP GI G KG+ G  
Sbjct: 102 GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSI 161

Query: 394 GPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPG-------- 445
                PGP+G  G  G  G  G+PGP G+PG  G  G PG  GP G  G PG        
Sbjct: 162 IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLN 221

Query: 446 VAGLPGEKGEKGESGEPGPKGQ----------QGVRGEPGYPGPSGDAGAPGVQGYPGPP 495
             G  GEKGE+G  G PGP GQ          +  +G+ G PG  G  G PG++G PGPP
Sbjct: 222 FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPP 281

Query: 496 GPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMM 555
           G  G  G +G  G+PG++G  G+D                         +    G  G+ 
Sbjct: 282 G--GEKGEKGEQGEPGKRGKPGKD------------------------GENGQPGIPGLP 315

Query: 556 GPPGPPGPPGYPGKQGPHGHPGPRGVPGIV----------GAVGQIGNTGPKGKRGEKGD 605
           G PG PG PG  G++G  G  GP G PG+V          G  G IG  G  G++GE+G 
Sbjct: 316 GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGF 375

Query: 606 PGEVGRGHPGMPGPPGI-----PGLPGRPGQAINGKDGDRGSPG--APGEAGRPGLPGPV 658
           PG   +G PG+PGPPG      PG PG PG+   G+ GD G PG   PG  G  G PG  
Sbjct: 376 PGI--QGPPGLPGPPGAAVMGPPGPPGFPGE--RGQKGDEGPPGISIPGPPGLDGQPGAP 431

Query: 659 GLPGFCEPAACLGASAYASARLTEPG 684
           GLPG   P    G     S  + EPG
Sbjct: 432 GLPG---PPGPAGPHIPPSDEICEPG 454



 Score =  186 bits (472), Expect = 6e-47
 Identities = 110/240 (45%), Positives = 130/240 (54%), Gaps = 41/240 (17%)

Query: 21   ALAQIRGPPGERGP------PGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPD 74
            AL   +G PG +GP      PGP GPPG+PG+ GI G+ G PG+ G PG  G  G  GP 
Sbjct: 1246 ALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPP 1305

Query: 75   GPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIG 134
            G  G PG  GL G KG+P   G+PGV G PG+ GP G+PG   AGP G PG +G P    
Sbjct: 1306 GLQGNPGRPGLNGMKGDP---GLPGVPGFPGMKGPSGVPGS--AGPEGEPGLIGPP---- 1356

Query: 135  IRGPKGDPGPDGPS----GPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQG 190
              GP G PGP G S    G  GPPG PG+PG ++GL             PG +GP GL G
Sbjct: 1357 --GPPGLPGPSGQSIIIKGDAGPPGIPGQPG-LKGL-------------PGPQGPQGLPG 1400

Query: 191  VKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHG 250
              G  G      DPG  G PG  G  G  G+ G+PG PG +G+ G PG  G +G  GP G
Sbjct: 1401 PTGPPG------DPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1454



 Score =  130 bits (326), Expect = 5e-30
 Identities = 91/247 (36%), Positives = 103/247 (41%), Gaps = 70/247 (28%)

Query: 462 PGPK----GQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEG 517
           PG K    G +G +GE G+PG  G  G PG  G  GPPGPRG  G+ G+PG PG +    
Sbjct: 34  PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPK---- 89

Query: 518 RDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGH-- 575
                                              G+ GPPG PG PG PG  G  GH  
Sbjct: 90  -----------------------------------GIRGPPGLPGFPGTPGLPGMPGHDG 114

Query: 576 -PGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAIN 634
            PGP+G+PG           G KG+RG  G PG  G   P  PGPPGIPG+ G PG  I 
Sbjct: 115 APGPQGIPGC---------NGTKGERGFPGSPGFPGLQGP--PGPPGIPGMKGEPGSIIM 163

Query: 635 ----GKDGDRGSPGAPGEAGRPGL---------PGPVGLPGFCEPAACLGASAYASARLT 681
               G  G+ G PG PG  G PG          PGP GL G   P    G          
Sbjct: 164 SSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQ 223

Query: 682 EPGSIKG 688
            P   KG
Sbjct: 224 GPKGEKG 230


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  540 bits (1391), Expect = e-153
 Identities = 323/726 (44%), Positives = 370/726 (50%), Gaps = 76/726 (10%)

Query: 20  LALAQIRGPPGERGPPGPPGPPGV------PGSDGIDGDNGPPGKAGPPGPKGEPGKAGP 73
           +A+  + G PG  GPPGPPGPPG       PGS G  G  G PG+AGP GP G PG  GP
Sbjct: 164 VAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGP 223

Query: 74  DGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP-GFAGPPGPPGPVGLPG- 131
            GP GK G  G  G  GE G  G PG+KG  G+PG PG+ G  GF G  G  G  G PG 
Sbjct: 224 SGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGL 283

Query: 132 --EIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQ 189
             E G+ G  G PGP GP G PG  G+PG PG   G  G+ D    ++  PG  GPPG  
Sbjct: 284 KGENGLPGENGAPGPMGPRGAPGERGRPGLPGAA-GARGN-DGARGSDGQPGPPGPPGTA 341

Query: 190 GVKGHAGKRGILG---DPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGET 246
           G  G  G +G +G    PG  G PG +G+ G  G  G  GPPGP GI G PG    KGE 
Sbjct: 342 GFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPG---GKGEM 398

Query: 247 GPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGI- 305
           GP G  G  G +GA GPPG  G  G PG  G  G+ G  G +G  G  G +G  G PG+ 
Sbjct: 399 GPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVP 458

Query: 306 -----NGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLP 360
                +GKDG+PG PG  G  G AG+ G+PG +G AG  G PG KG  G++G PGP G  
Sbjct: 459 GAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPR 518

Query: 361 GFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQ 420
           G +G PG++G PG  G  G  G  G  G  G+ GP G  G  GR GP G  GP G PG  
Sbjct: 519 GAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVM 578

Query: 421 GLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGE---------------KGESGEPGPK 465
           G PG KG+ G+PGK G RG  G PG  G PG+ GE               KG++G PGP+
Sbjct: 579 GFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQ 638

Query: 466 GQQGV---------RGEPGYPGPSGDAGAPGV------QGYPGPPGPRGLAGN---RGVP 507
           G QG+          G+PG PGP GDAGAPG        G PG  GP GLAG    RG  
Sbjct: 639 GLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGA 698

Query: 508 GQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYP 567
           G PG +G +G               LQ    E          G +G  GP G  G PG P
Sbjct: 699 GPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGE---------RGGLGSPGPKGDKGEPGGP 749

Query: 568 GKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-RGHP---GMPGPPGIP 623
           G  G  G  GPRG  G +G  G  G  G KG+ G  G PG  G RG P   G  GPPG  
Sbjct: 750 GADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPA 809

Query: 624 GLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASARLTEP 683
           G PG PGQ  NG+ G +G  GAPGE G  G PG  G PG   PA   G       R    
Sbjct: 810 GFPGAPGQ--NGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGER---- 863

Query: 684 GSIKGP 689
           GS  GP
Sbjct: 864 GSPGGP 869



 Score =  532 bits (1371), Expect = e-151
 Identities = 332/768 (43%), Positives = 370/768 (48%), Gaps = 121/768 (15%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGE---PGKAGPDGPDGKPGID 83
            GP GERG  G PG PG  G DG DG  G PG  G PG  GE   PG  GP GP+G PG  
Sbjct: 444  GPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEK 503

Query: 84   GLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP-GFAGPPGPPGPVGLPGEIGIRGPKGDP 142
            G  G +G PGP G  G  G+PG  G PG PG  G  G PG PG  G PG  G +G  G P
Sbjct: 504  GPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRP 563

Query: 143  GPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCP--PGMKGPPGLQGVKGH------ 194
            GP GPSGP G PG  G PG  +G +G+         P  PG +GPPG  G  G       
Sbjct: 564  GPPGPSGPRGQPGVMGFPGP-KGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGP 622

Query: 195  ---AGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKG------E 245
                G +G  G PG QG  G  G  G  GE G PG PGP+G  G PG  G KG      E
Sbjct: 623  TGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGE 682

Query: 246  TGPHGYKGMVGAIGATGPPGEEG------PRGPPGRAGEKGDEGSPGIRGPQGITGPKGA 299
             GP G  G  G  G  GPPG EG      P GPPG AG  G +G PG RG  G  GPKG 
Sbjct: 683  RGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGD 742

Query: 300  TGPPGINGKDGTPGTPGMKGSAGQ------AGQPGSPGHQGLAGVPGQPGTKGGPGDQGE 353
             G PG  G DG PG  G +G  G       AGQPG  G  G  G+PG  G +G PG++GE
Sbjct: 743  KGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGE 802

Query: 354  PGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGP---KGE 410
             GP G  GF G PG+ GEPG +GE G  G  G+ G  G  GP G  GP G  GP   KGE
Sbjct: 803  TGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGE 862

Query: 411  QGPPGIPGPQGLPGVKG---------------DKGSPGKTGPRGKVGDPGVAGLPGEKGE 455
            +G PG PG  G PG +G                 GSPGK GP G  G+ G  G PG  G 
Sbjct: 863  RGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGP 922

Query: 456  KGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPG---PRG------------- 499
            KG++G+PG KG  G +G PG PGP G AG  G +G  GPPG   PRG             
Sbjct: 923  KGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGK 982

Query: 500  -----LAGNRGVPGQ---PGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGA 551
                 L+G RG PG    PG  G  G    D +     L              +  + GA
Sbjct: 983  PGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGA 1042

Query: 552  VGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG- 610
             G  G PGPPGP G  GK G  G  GP G  G  G  G  G  GP+G RG+KG+ GE G 
Sbjct: 1043 PGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGA 1102

Query: 611  ---RGHPGMPGPPGIPGLPGRPGQ--AIN-----------------GKDG---------- 638
               +GH G PG PG PG PG  GQ  AI                  GKDG          
Sbjct: 1103 AGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGP 1162

Query: 639  --------DRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASA 678
                    +RGS G+PG  G+PG PGP G PG C    C G  A A A
Sbjct: 1163 PGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPC----CGGVGAAAIA 1206



 Score =  406 bits (1044), Expect = e-113
 Identities = 260/647 (40%), Positives = 300/647 (46%), Gaps = 102/647 (15%)

Query: 121 PGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPP 180
           P P  P G    +  + P     P    GP GP G PG PG I G  G           P
Sbjct: 75  PNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPG-IPGRNGDPGIPGQPG-SP 132

Query: 181 GMKGPPGL-----------------QGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQG 223
           G  GPPG+                   VK      G+ G PG  G PGP G  G SG  G
Sbjct: 133 GSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPG 192

Query: 224 IPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEG 283
            PG PG QG  G PG AGP G  GP       GAIG +GP G++G  G PGR GE+G  G
Sbjct: 193 SPGSPGYQGPPGEPGQAGPSGPPGP------PGAIGPSGPAGKDGESGRPGRPGERGLPG 246

Query: 284 SPGIRGPQGI---------------TGPKGATGPPGINGKDGTP---------------- 312
            PGI+GP GI                G KG TG PG+ G++G P                
Sbjct: 247 PPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPG 306

Query: 313 --GTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGT---KGGPGDQGEPGPQGLPGFSGPPG 367
             G PG+ G+AG  G  G+ G  G  G PG PGT    G PG +GE GP G PG +G PG
Sbjct: 307 ERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPG 366

Query: 368 KEGEPGPRGEI------GPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQG 421
           + GEPGP+G        GP GI G  G +GE GP G PG  G  G +   GPPG  G  G
Sbjct: 367 QRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGAR---GPPGPAGANG 423

Query: 422 LPGVKGDKGSPGKT------GPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGV----- 470
            PG++G  G PGK       GPRG+ G+ G+ G+PG KGE G+ G PG  G  G+     
Sbjct: 424 APGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAG 483

Query: 471 -RGEPGYPGPSGDAGAP------GVQGYPGPPGPRGLA---GNRGVPGQPGRQGVEGRDA 520
            RG PG+ GP+G  G P      G +G PGP GPRG A   G  GVPG PG +G+ G   
Sbjct: 484 ERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPG 543

Query: 521 TDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPH---GHPG 577
                        Q +             G  G+MG PGP G  G PGK G     G PG
Sbjct: 544 GPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPG 603

Query: 578 PRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG----RGHPGMPGPPGIPGLPGRPG--- 630
           P+G PG  G  G  G  GP G  G+KGD G  G    +G PG  GPPG  G PG PG   
Sbjct: 604 PQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKG 663

Query: 631 -QAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYA 676
                G  G +G  GAPGE G PGL G  GL G   P    G    A
Sbjct: 664 DAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAA 710



 Score =  360 bits (924), Expect = 2e-99
 Identities = 199/451 (44%), Positives = 238/451 (52%), Gaps = 47/451 (10%)

Query: 22   LAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGE---------PGKAG 72
            +A  RG PGERG  GPPGP G PG+ G +G+ G  G+ G PG KGE         PG +G
Sbjct: 790  IAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSG 849

Query: 73   PDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPG-------PGFAGPPGPPG 125
            P GP G  G+ G  G+ G PG  G PG +G PG PG  G PG       PG  GPPGP G
Sbjct: 850  PAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAG 909

Query: 126  PVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGT--IQGLEGSADFLCPTNCPPGMK 183
              G PG  G+ GPKGD G  G  G PG  G PG PG   I G+ G+     P    PG +
Sbjct: 910  NTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGM-PGPR 968

Query: 184  GPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPK 243
            G PG QGVKG +GK G  G  G +G PGP+G  G +G  G PG  G  G  G PG  G  
Sbjct: 969  GSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSP 1028

Query: 244  GETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPP 303
            G  G  G  G  GA GA G PG  GP GP G++G++G+            +GP G  G P
Sbjct: 1029 GGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGE------------SGPAGPAGAP 1076

Query: 304  GINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFS 363
            G  G  G PG  G +G  G+ G+ G+ G +G  G PG PG  G PG  G+ G  G PG +
Sbjct: 1077 GPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPA 1136

Query: 364  GPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLP 423
            GP         RG +GP G  G+ G  G  GP+G PGP+G +G +G +G PG PG  G P
Sbjct: 1137 GP---------RGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPP 1187

Query: 424  GVKGDKGSPGKTGP-RGKVGDPGVAGLPGEK 453
                  G PG  GP  G VG   +AG+ GEK
Sbjct: 1188 ------GPPGAPGPCCGGVGAAAIAGIGGEK 1212



 Score =  218 bits (554), Expect = 2e-56
 Identities = 133/298 (44%), Positives = 150/298 (50%), Gaps = 42/298 (14%)

Query: 20   LALAQIRGPPGERGPPGPPGP---P---GVPGSDGIDGDNGPPGKAGPPGPKGEP---GK 70
            L +A I G  G  GPPG PGP   P   GV G  G  G NG  G+ GPPGP+G P   G 
Sbjct: 947  LGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGT 1006

Query: 71   AGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLP 130
            AG  G DG PG DGL G  G PG  G  G  G PG PG PG P     GPPGP GP G  
Sbjct: 1007 AGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHP-----GPPGPVGPAGKS 1061

Query: 131  GEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQG 190
            G+      +G+ GP GP+G PGP G  G PG  QG             P G KG  G +G
Sbjct: 1062 GD------RGESGPAGPAGAPGPAGSRGAPGP-QG-------------PRGDKGETGERG 1101

Query: 191  VKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHG 250
              G  G RG  G+PG  G PGP      +G+QG  G PGP G RG  G +GP G+ G  G
Sbjct: 1102 AAGIKGHRGFPGNPGAPGSPGP------AGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSG 1155

Query: 251  YKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGK 308
            + G +G  G  G  GE G  G PG  G+ G  G PG  GP    G  GA    GI G+
Sbjct: 1156 HPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGP--CCGGVGAAAIAGIGGE 1211



 Score =  191 bits (485), Expect = 2e-48
 Identities = 125/335 (37%), Positives = 143/335 (42%), Gaps = 56/335 (16%)

Query: 390 QGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPG---------------- 433
           Q    P   P  QG QGPKG+ GPPGIPG           G PG                
Sbjct: 90  QPPTAPTRPPNGQGPQGPKGDPGPPGIPGR---------NGDPGIPGQPGSPGSPGPPGI 140

Query: 434 ----KTGPR------------------GKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVR 471
                TGP+                  G  G PG AG PG  G  G SG PG  G  G +
Sbjct: 141 CESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQ 200

Query: 472 GEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALK 531
           G PG PG +G +G PG  G  GP GP G  G  G PG+PG +G+ G              
Sbjct: 201 GPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFP 260

Query: 532 MLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQI 591
            ++        + ++   GA G+ G  G PG  G PG  GP G PG RG PG+ GA G  
Sbjct: 261 GMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGAR 320

Query: 592 GNTGPKGKRGEKGDPGEVG-RGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAG 650
           GN G +G  G+ G PG  G  G PG PG  G  G  G PG   NG  G RG PG  G AG
Sbjct: 321 GNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGS--NGAPGQRGEPGPQGHAG 378

Query: 651 RPGLPGPVGL------PGFCEPAACLGASAYASAR 679
             G PGP G+       G   PA   GA     AR
Sbjct: 379 AQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGAR 413


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score =  539 bits (1389), Expect = e-153
 Identities = 313/679 (46%), Positives = 356/679 (52%), Gaps = 50/679 (7%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGI------DGDNGPPGKAGPPGPKGEPGKAGPDGPDGKP 80
            G PGE+GPPG PG PG+PGSDG       +G  G  G  GPPG  G PG  GP G  G  
Sbjct: 659  GTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTS 718

Query: 81   GIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPG-PGFAGPPGPPGPVGLPGEIGIRGPK 139
            G  GL G KGE G  G PG KG  GL G  G PG PG  G  GP GP G  G+ G  GP 
Sbjct: 719  GNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPP 778

Query: 140  GDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGP------PGLQGVKG 193
            G  G  G  G PG PG PGRPG     +GS  F  P   P G KG       PGL+G +G
Sbjct: 779  GSAGEKGKLGVPGLPGYPGRPGP----KGSIGFPGPLG-PIGEKGKSGKTGQPGLEGERG 833

Query: 194  HAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKG 253
              G RG  G PG  G+PGPKGDVG  G  GIPG  G  G++G PG  GPKG  G  G  G
Sbjct: 834  PPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDG 893

Query: 254  MVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPG 313
              G  G  G  G +G  GPPG AG  G +G  G  GP G  GP G  GPPG   + G PG
Sbjct: 894  RPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPG---EQGLPG 950

Query: 314  TPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGK---EG 370
              G +G+ G+ G PG  G +G AG+ G PG KGGPGD   PGP GL G  GPPG     G
Sbjct: 951  LEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGD---PGPTGLKGDKGPPGPVGANG 1007

Query: 371  EPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKG 430
             PG RG +GP G +G  G  G  GPVG   P G++G +GE+GPPG  G  G+PG  G  G
Sbjct: 1008 SPGERGPLGPAGGIGLPGQSGSEGPVG---PAGKKGSRGERGPPGPTGKDGIPGPLGPLG 1064

Query: 431  SPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQG 490
             PG  GP G+ GD G  G PG KG KG+ G+ GP GQ G+RG  G+PGP G  GA G +G
Sbjct: 1065 PPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRG 1124

Query: 491  YPGPPGPRGLAGNRG---VPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKRE 547
             PG  G +G  G RG   V G PG QG+ G       + DV        +        R 
Sbjct: 1125 PPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVG------SMGPHGAPGPRG 1178

Query: 548  ALGAVGMMGPPGPPGPPGYPG------KQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRG 601
              G  G  G PG PG  G PG      ++G  G PGP G PGI G  G IG  G  G  G
Sbjct: 1179 PQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSG 1238

Query: 602  EKGDPGEVGR----GHPGMPGPPGIPGLPGRPGQ-AINGKDGDRGSPGAPGEAGRPGLPG 656
              G PG+ G     G  G  GP G+PG  G PG   ++G DG  G  G PG+ G PG PG
Sbjct: 1239 AAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPG 1298

Query: 657  PVGLPGFCEPAACLGASAY 675
              G PG   P    G S +
Sbjct: 1299 ASGEPGAPGPPGKRGPSGH 1317



 Score =  520 bits (1340), Expect = e-147
 Identities = 340/840 (40%), Positives = 391/840 (46%), Gaps = 178/840 (21%)

Query: 14   LLQVVVLALAQIRGPPGERGPPGPPGPPGVP---GSDGIDGDNGPPGKAGPPGPKGEPGK 70
            +LQ   L++    GP G  G PGP G PG P   G +G +G  GP G  GP GP G  GK
Sbjct: 469  VLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGK 528

Query: 71   AGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQP---------GLPGPPGLPGP-GFAGP 120
             G  G DG  G+ G TG KG+ G  G+PG+ G+          G PGPPG  G  G  GP
Sbjct: 529  MGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGP 588

Query: 121  PGPPGPVGLPGEIGIRGPKGDPGP------------DGPSGPPGPPGKPGRPGTIQGLEG 168
            PGP G  G PG  G+ GP+G PGP             G  G  GPPG+PG PG  QG  G
Sbjct: 589  PGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQ-QGNHG 647

Query: 169  SADFLCPTNC--PPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPG 226
            S     P      PG KGPPG  G+ G  G  G LG PGH+G  G KG  G  G  G PG
Sbjct: 648  SQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPG 707

Query: 227  PPGPQGIR---------------------------------GYPGMAGPKGETGPHGYKG 253
             PGP+G++                                 G PG  GP+GE GP G KG
Sbjct: 708  YPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKG 767

Query: 254  MVGAIGATGPPGEEGPRGP---------PGRAGEKGDEGSPGIRGPQGITGPKGATGPPG 304
              G  G  GPPG  G +G          PGR G KG  G PG  GP G  G  G TG PG
Sbjct: 768  QAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPG 827

Query: 305  INGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGE---PGPQGLPG 361
            + G+ G PG+ G +G  G  GQPG  G  G  G PG PG KG PG QG    PGP+G PG
Sbjct: 828  LEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPG 887

Query: 362  FSGPPGKEGEPGPRGE---------------IGPQGIMGQKGDQGERGPVGQPGP----- 401
              G  G+ G PG RGE               +GPQG  G+ G  GERGP G PGP     
Sbjct: 888  HQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQG 947

Query: 402  ----QGRQGPKGEQGPP------------GIPGPQGLP------GVKGDKGSP------G 433
                +GR+G KGE GPP            G PGP+G P      G+KGDKG P      G
Sbjct: 948  LPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANG 1007

Query: 434  KTGPRGKVGDPGVAGLPGE------------KGEKGESGEPGPKGQQGV------RGEPG 475
              G RG +G  G  GLPG+            KG +GE G PGP G+ G+       G PG
Sbjct: 1008 SPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPG 1067

Query: 476  YPGPS------GDAGAPGVQGY------PGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQ 523
              GPS      GD GAPG +G        GPPG  G+ G  G PG PG  G +GR     
Sbjct: 1068 AAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPG 1127

Query: 524  HIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGY---PGKQGPHGHPGPR- 579
                     L  Q  +  V      +G  G+ G PGPPG  G     G  GPHG PGPR 
Sbjct: 1128 ---------LFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRG 1178

Query: 580  --------GVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQ 631
                    G PG+ G VGQ G  G KG+RG+ GDPG  G   PG+PGP G  G  G  G 
Sbjct: 1179 PQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGA--PGIPGPKGDIGEKGDSGP 1236

Query: 632  AINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAY--ASARLTEPGSIKGP 689
              +G  G  G  G PGE G  G  GP GLPG   P    G S    +     +PG + GP
Sbjct: 1237 --SGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGP 1294



 Score =  515 bits (1326), Expect = e-146
 Identities = 301/686 (43%), Positives = 359/686 (52%), Gaps = 63/686 (9%)

Query: 27   GPPGERGPPGPPGPPGVPGS---DGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGID 83
            GP GE+G  G  G PG+ G     G  G+ G PG  G PGPKG+ G+ G  G  G+ G+ 
Sbjct: 812  GPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLP 871

Query: 84   GLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP-GFAGPPGPPGPVGLPGEIGIRGPKGDP 142
            GL G  G PGP G PG +G+ G PG PG  G  GF G  GPPGP G+ G  G  G  G  
Sbjct: 872  GLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPL 931

Query: 143  GPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILG 202
            G  GP GPPGPPG+ G PG ++G EG+   L P   P G +GP GL+G  G  G  G  G
Sbjct: 932  GERGPPGPPGPPGEQGLPG-LEGREGAKGELGPPG-PLGKEGPAGLRGFPGPKGGPGDPG 989

Query: 203  DPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATG 262
              G +G  GP G VGA+G  G  GP GP G  G PG +G +G  GP G KG  G  G  G
Sbjct: 990  PTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPG 1049

Query: 263  P------PGEEGPRGPPGRAG------EKGDEGSPGIRGPQGITGPKGATGPPGINGKDG 310
            P      PG  GP GPPG AG      +KGD G+PG +G +G  G  G  G PGI G  G
Sbjct: 1050 PTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAG 1109

Query: 311  TPGTPGMKGSAGQAGQPGSPGHQG---------------LAGVPGQPGTKGGPGDQGEPG 355
             PG PG  G+ G+ G PG  G +G               L G+PG PG KG  GD G  G
Sbjct: 1110 HPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMG 1169

Query: 356  PQGLPGF---SGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQG 412
            P G PG     GP G EG PG  G +G  G +G+KG++G+ G  G PG  G  GPKG+ G
Sbjct: 1170 PHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIG 1229

Query: 413  PPGIPGPQGLPGVKGDKGSPGKTGPRGKVG------------DPGVAGLPGEKGEKGESG 460
              G  GP G  G  G KG PG+ G +G VG            DPGV+G+ G  GEKG+ G
Sbjct: 1230 EKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPG 1289

Query: 461  EPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDA 520
            + G  G  G  GEPG PGP G  G  G  G  G  G +G  G  G  G PGR G  G   
Sbjct: 1290 DVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARG 1349

Query: 521  TDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRG 580
                +    L+ +   + E  +      LGA G MGPPGP GP G PG +   G  GP+G
Sbjct: 1350 PPGRVGPEGLRGIPGPVGEPGL------LGAPGQMGPPGPLGPSGLPGLK---GDTGPKG 1400

Query: 581  VPGIVGAVGQIGNTGPKGKRGEKGDPGEVG----RGHPGMPGPPGIPGLPGRPGQAINGK 636
              G +G +G IG  G  G++G++G PG  G    +G PG PGP G  G PG PG A  G 
Sbjct: 1401 EKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVA--GP 1458

Query: 637  DGDRGSPGAPGEAGRPGLPGPVGLPG 662
             G +GS G+PG  G  G  GP G PG
Sbjct: 1459 LGQKGSKGSPGSMGPRGDTGPAGPPG 1484



 Score =  468 bits (1205), Expect = e-132
 Identities = 275/628 (43%), Positives = 316/628 (50%), Gaps = 95/628 (15%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
            GP GERGPPGPPGPPG  G  G++G  G  G+ GPPGP G+      +GP G  G  G  
Sbjct: 929  GPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGK------EGPAGLRGFPGPK 982

Query: 87   GAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDG 146
            G  G+PGP G+ G KG PG  G  G PG    GP GP G +GLPG+ G  GP G  G  G
Sbjct: 983  GGPGDPGPTGLKGDKGPPGPVGANGSPGE--RGPLGPAGGIGLPGQSGSEGPVGPAGKKG 1040

Query: 147  PSG---PPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGD 203
              G   PPGP GK G PG                 P G  GPPG  G  G  G +G +G 
Sbjct: 1041 SRGERGPPGPTGKDGIPG-----------------PLGPLGPPGAAGPSGEEGDKGDVGA 1083

Query: 204  PGHQGKPGPKGDVGASGEQGIPGP---PGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGA 260
            PGH+G  G KGD G  G+ GI GP   PGP G  G  G  GP G  G  G  G+ G +G 
Sbjct: 1084 PGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGV 1143

Query: 261  TGPPGEEGPRGPPGRAGEKGDEGSPGIRG---PQGITGPKGATGPPGINGKDGTPGTPGM 317
             GPPG +G  GPPG  GE GD GS G  G   P+G  GP G+ G PG+ G  G PG  G 
Sbjct: 1144 IGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGE 1203

Query: 318  KGSAGQAGQPGSPGHQGLAGVPGQPGTKGG---------PGDQGEPGPQGLPGFSGPPGK 368
            KG  G AG PG PG  G+ G  G  G KG          PG +G PG  G  G  GP G 
Sbjct: 1204 KGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGL 1263

Query: 369  EGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGP------QGL 422
             G+ GP G+ G  GI G  G++G+ G VG PGP G  G  G  GPPG  GP      +G 
Sbjct: 1264 PGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGR 1323

Query: 423  PGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGY---PGP 479
             G KG KG PG  GP G+ G  G  G PG  G +G  G PGP G+ G+ G PG    PGP
Sbjct: 1324 EGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGP 1383

Query: 480  SGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAE 539
             G +G PG++G  GP G +G  G  G+ G PG  G +G    DQ +  V           
Sbjct: 1384 LGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKG----DQGLPGVQ---------- 1429

Query: 540  VAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGK 599
                      G  G  G PGPPGP       G  GHPGP GV             GP G+
Sbjct: 1430 ----------GPPGPKGDPGPPGP------IGSLGHPGPPGV------------AGPLGQ 1461

Query: 600  RGEKGDPGEVG-RGHPGMPGPPGIPGLP 626
            +G KG PG +G RG  G  GPPG PG P
Sbjct: 1462 KGSKGSPGSMGPRGDTGPAGPPGPPGAP 1489



 Score =  436 bits (1122), Expect = e-122
 Identities = 257/571 (45%), Positives = 306/571 (53%), Gaps = 76/571 (13%)

Query: 23   AQIRGPPGERGPPGPPGPPGVPGSDGIDGD---NGPPGKAGPPGPKGE---PGKAGPDGP 76
            A +RG PG +G PG PGP G+ G  G  G    NG PG+ GP GP G    PG++G +GP
Sbjct: 973  AGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGP 1032

Query: 77   DGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIR 136
             G  G  G  G +G PGP G  G+ G  G  GPPG  GP  +G  G  G VG PG  G +
Sbjct: 1033 VGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGP--SGEEGDKGDVGAPGHKGSK 1090

Query: 137  GPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAG 196
            G KGD GP G  G  GP G PG PG     +G+           G +GPPGL G KG  G
Sbjct: 1091 GDKGDAGPPGQPGIRGPAGHPGPPGA----DGA----------QGRRGPPGLFGQKGDDG 1136

Query: 197  KR---GILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKG 253
             R   G++G PG QG PGP G+ G  G+ G  GP       G PG  GP+G TG  G  G
Sbjct: 1137 VRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGP------HGAPGPRGPQGPTGSEGTPG 1190

Query: 254  MVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGI---NGKDG 310
            + G +G  G  GE+G RG    AG+ G  G+PGI GP+G  G KG +GP G     GK G
Sbjct: 1191 LPGGVGQPGAVGEKGERGD---AGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKG 1247

Query: 311  TPGTPGMKGSAGQAGQPGS---PGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPG 367
             PG  G KGS G  G PG    PG  G++G+ G PG KG PGD G PGP   PG SG P 
Sbjct: 1248 PPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGP---PGASGEP- 1303

Query: 368  KEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQ---GRQGPKGEQGPPGIPGPQGLPG 424
              G PGP G+ GP G MG++G +GE+G  G+PGP    GR GP G +GPPG  GP+GL G
Sbjct: 1304 --GAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRG 1361

Query: 425  VKGDKGSPGKTGPRGKVGDP---GVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSG 481
            + G  G PG  G  G++G P   G +GLPG KG+ G  GE G  G  G+ G PG  G  G
Sbjct: 1362 IPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKG 1421

Query: 482  DAGAPGVQGYPGP---PGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLA 538
            D G PGVQG PGP   PGP G  G+ G PG PG  G  G+  +                 
Sbjct: 1422 DQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGS----------------- 1464

Query: 539  EVAVSAKREALGAVGMMGPPGPPGPPGYPGK 569
                     ++G  G  GP GPPGPPG P +
Sbjct: 1465 ----KGSPGSMGPRGDTGPAGPPGPPGAPAE 1491



 Score =  429 bits (1103), Expect = e-120
 Identities = 285/702 (40%), Positives = 330/702 (47%), Gaps = 107/702 (15%)

Query: 58   KAGPPGPKGEPGKAGPDGPDGK----------PGIDGLTGAKGEPGPMGIPGVKGQPGLP 107
            KA     +G+    GPD    +          PG  G  GAKGEP  +     KGQ    
Sbjct: 338  KAAREDEEGDDSTMGPDFRAAEYPSRTQFQIFPGA-GEKGAKGEPAVIE----KGQQ-FE 391

Query: 108  GPPGLPGP-GFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGK---------- 156
            GPPG PGP G  GP GPPGP G PG+ G  GP G PG  G  G  GPPG           
Sbjct: 392  GPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAG 451

Query: 157  ---PGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPK 213
                G P + Q  +  A  L  T     MKGPPG  G+ G  G  G+   PGH   PG K
Sbjct: 452  GSFKGPPVSFQQAQAQA-VLQQTQL--SMKGPPGPVGLTGRPGPVGL---PGH---PGLK 502

Query: 214  GDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPP 273
            G+ GA G QG   P G QG  G PG  G  G  G  G +G+ G  G  G  G +G  G P
Sbjct: 503  GEEGAEGPQG---PRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLP 559

Query: 274  GRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQ 333
            G  G++GD G  G  GP G  G +GA GPPG  G+ G PG  G+ G  G  G  G PG  
Sbjct: 560  GEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVT 619

Query: 334  GLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGER 393
            G+ G PG  G  G PG+ G PG QG  G  G PG +G  G  GE GP G  G  G  G  
Sbjct: 620  GIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSD 679

Query: 394  GPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEK 453
            GP+G PG +G  G KG QGPPG  GP G PG +G KG+ G  G +G+ G+ G  G PG K
Sbjct: 680  GPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFK 739

Query: 454  GE---------------KGESGEPGPKGQQGVRGEPGYPGPSGD---AGAPGVQGYPGPP 495
            G+               +GE G  GPKGQ G  GE G PG +G+    G PG+ GYPG P
Sbjct: 740  GDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRP 799

Query: 496  GPR------------------------GLAGNRGVPGQPGRQGVEGRDATDQHIVDVALK 531
            GP+                        GL G RG PG  G +G  G         DV   
Sbjct: 800  GPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVG-- 857

Query: 532  MLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQI 591
                Q     +  ++   G  G+ GPPG PGP G PG QG  G PG  G  G +G  GQ 
Sbjct: 858  ----QDGAPGIPGEK---GLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQT 910

Query: 592  GNTGPKGKRGEKGDPGEVG----RGHPGMPGPPGIPGLPGRPGQ----------AINGKD 637
            G  GP G  G +G  GEVG    RG PG PGPPG  GLPG  G+             GK+
Sbjct: 911  GPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKE 970

Query: 638  GDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASAR 679
            G  G  G PG  G PG PGP GL G   P   +GA+     R
Sbjct: 971  GPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGER 1012



 Score =  278 bits (710), Expect = 2e-74
 Identities = 164/366 (44%), Positives = 185/366 (50%), Gaps = 57/366 (15%)

Query: 22   LAQIRGPPGER------------GPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPG 69
            L  + GPPGE+            G PGP GP G  GS+G  G  G  G+ G  G KGE G
Sbjct: 1149 LQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERG 1208

Query: 70   KAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPG-PGFAGPPGPPGPVG 128
             AG  GP G PGI G  G  GE G  G  G  G PG  GPPG  G  G  GP G PG +G
Sbjct: 1209 DAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLG 1268

Query: 129  LPGEIGIR------GPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGM 182
             PG+ G+       G KGDPG  G  GPPG  G+PG PG                 PPG 
Sbjct: 1269 PPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPG-----------------PPGK 1311

Query: 183  KGPPGLQGVKGHAGKRGILGDPGHQGKP---------GPKGDVGASGEQGIPGPPGPQGI 233
            +GP G  G +G  G++G  G+PG  G P         GP G VG  G +GIPGP G  G+
Sbjct: 1312 RGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGL 1371

Query: 234  RGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGP------RGPPGRAGEKGDEGSPGI 287
             G PG  GP G  GP G  G+    G TGP GE+G        GPPG AGEKGD+G PG+
Sbjct: 1372 LGAPGQMGPPGPLGPSGLPGLK---GDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGV 1428

Query: 288  RGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGG 347
            +GP    GPKG  GPPG  G  G PG PG+ G  GQ G  GSPG  G  G  G  G  G 
Sbjct: 1429 QGP---PGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGP 1485

Query: 348  PGDQGE 353
            PG   E
Sbjct: 1486 PGAPAE 1491



 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 52/113 (46%), Positives = 57/113 (50%), Gaps = 24/113 (21%)

Query: 20   LALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGK 79
            + L  + GPPGE G  G  G PGV G               PPGPKG+PG  GP G  G 
Sbjct: 1405 IGLIGLIGPPGEAGEKGDQGLPGVQG---------------PPGPKGDPGPPGPIGSLGH 1449

Query: 80   PGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPG-PVGLPG 131
            PG  G+       GP+G  G KG PG  GP G  GP  AGPPGPPG P  L G
Sbjct: 1450 PGPPGVA------GPLGQKGSKGSPGSMGPRGDTGP--AGPPGPPGAPAELHG 1494


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  539 bits (1388), Expect = e-153
 Identities = 309/672 (45%), Positives = 354/672 (52%), Gaps = 53/672 (7%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
            GP G RG  GP G PG  G+ G DG  GPPG+ GP GP+G  G  GP GP G PG DGL 
Sbjct: 898  GPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLP 957

Query: 87   GAKGEPGPMGIPGVKGQPGLPGPPGLPGP-------------GFAGPPGPPGPVGLPGEI 133
            G    PG  G  G +G+ G PGP G+ GP             G  GPPGPPG  GLPG  
Sbjct: 958  G---HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 1014

Query: 134  GIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKG 193
            G  G KGDPGP G SG  GP G  G PG  +GL             PG +G PGL+G +G
Sbjct: 1015 GKEGAKGDPGPQGISGKDGPAGLRGFPGE-RGL-------------PGAQGAPGLKGGEG 1060

Query: 194  HAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKG 253
              G  G +G PG +G  G  G +G  G  G  GPPGP G +G PG  GP+G  G  G +G
Sbjct: 1061 PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQG 1120

Query: 254  MVGAIGATGP---PGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDG 310
             VG  G  GP   PGE+G +G  G  G+KG +G  G  GP G  G +G  G PGI G DG
Sbjct: 1121 PVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1180

Query: 311  TPGTPGMKGSAGQAGQ------PGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSG 364
             PG  G +G  GQ G       PG PG  GL G+PG PG KG  GD G  GP G PG  G
Sbjct: 1181 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRG 1240

Query: 365  PPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQG---PKGEQGPPGIPGPQG 421
            P G  G  GP+G  G  G +G  G++GE G  G PGP G  G   PKGE+G  G  GP G
Sbjct: 1241 PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPG 1300

Query: 422  LPGVKGDKGSPGKTGPRGK---VGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPG 478
              G  G KG PG  GP+G    VG PG  G PGE G  G+ G  G KG+ G  G+PG PG
Sbjct: 1301 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1360

Query: 479  PSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHI--VDVALKMLQEQ 536
            PSG+AG PG  G  GPPG  G  G +G  G  G  G EG       +     A K   E 
Sbjct: 1361 PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEG 1420

Query: 537  LAEVAVSAKREAL-GAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTG 595
            L  +      + L GA G  GPPGP GPPG PG +G  G  G +G PG++G +G  G  G
Sbjct: 1421 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG 1480

Query: 596  PKGKRG---EKGDPGEVGRGH-PGMPGPPGIPGLPGRPG-QAINGKDGDRGSPGAPGEAG 650
             KG RG    +G PG  G G  PG  GP G PG PG PG Q   G  G  G  G  G++G
Sbjct: 1481 EKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSG 1540

Query: 651  RPGLPGPVGLPG 662
             PG PG  G PG
Sbjct: 1541 LPGPPGSPGPPG 1552



 Score =  536 bits (1380), Expect = e-152
 Identities = 326/737 (44%), Positives = 375/737 (50%), Gaps = 118/737 (16%)

Query: 26   RGPPGERGPPGPPGPPGVPGSDGIDGDNGP---PGKAGPPGPKGEPGKAGPDGPDGKPGI 82
            +G  GERGP GPPGPPG  G  G DG+ GP   PG+AGP G  G  G  G  G  G  G+
Sbjct: 624  KGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV 683

Query: 83   DGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP-GFAGPPGPPGPVGLPGEIGI---RGP 138
            DG  G KG  GP G PG  GQ G PGP GLPGP G  GPPG  GP G PG  G+    GP
Sbjct: 684  DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGP 743

Query: 139  KGDPGPDGPS------GPPGPPGKPGRPGT--------IQGLEGSADFLCPTNCPPGMKG 184
             G PG +G S      GPPGP G  G PG         ++GL+GS          PG KG
Sbjct: 744  PGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGF-PGFKG 802

Query: 185  PPGLQGVKGHAGK---RGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAG 241
              GL+G +G  G+   RG  G  G +G+ GP GD G SG+ G  G  G  G+ GYPG  G
Sbjct: 803  DMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG 862

Query: 242  PKGETGPHGYKGMVGAIGA---------------TGPPGEEGPRGPPGRAGEKGDEGS-- 284
            PKG TG  G+ G  G  GA               TGP G  G RGP G+ G KG  G   
Sbjct: 863  PKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDG 922

Query: 285  ----PGIRGPQGITGP---KGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAG 337
                PG RGPQG  GP    G  GPPG  GKDG PG PG +G  G  G+ G PG  G+ G
Sbjct: 923  PPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVG 982

Query: 338  VPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQ----------- 386
              G  G  G  G++G PGP G PG  G PG  G+ G +G+ GPQGI G+           
Sbjct: 983  PQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPG 1042

Query: 387  ----------------KGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKG 430
                            +G QG  GPVG PG +G  G  G  G PG PGPQG PG  G+KG
Sbjct: 1043 ERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKG 1102

Query: 431  SPGKTGPRGKVGDPGV------------AGLPGEKGEKGESGEPGPKGQQGVRGEPGYPG 478
            +PG+ GP+G  G  GV            AG PGE G+KGE GEPG KG +G +GE G PG
Sbjct: 1103 APGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPG 1162

Query: 479  P---SGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQE 535
            P    G  GAPG+ G  G PGPRG  G  G  G  G +G  G          + L+ L  
Sbjct: 1163 PPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG------PIGLQGLPG 1216

Query: 536  QLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTG 595
               E          G  G +GP GPPGPPG  G QGP+G  GP+G PG VG+VG +G  G
Sbjct: 1217 PPGE---------KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKG 1267

Query: 596  PKGKRGEKGDPGEVG-------RGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGA--- 645
              G+ G  G PGE G       RG  G  GPPG  G PG  G    G DG +G+PG    
Sbjct: 1268 EPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPP--GDDGPKGNPGPVGF 1325

Query: 646  PGEAGRPGLPGPVGLPG 662
            PG+ G PG PGP G  G
Sbjct: 1326 PGDPGPPGEPGPAGQDG 1342



 Score =  533 bits (1373), Expect = e-151
 Identities = 323/740 (43%), Positives = 365/740 (49%), Gaps = 83/740 (11%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
            GP GE GP GP G  G  G  G  G  G  GK G PG  G PG+ GP G  G PG  G  
Sbjct: 817  GPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGAN 876

Query: 87   GAKGEPGPMGIPGVKGQPG---------LPGPPGLPGP-GFAGPPGPPGPVGLPGEIGIR 136
            G KG  G  G PG +GQ G           GP G PGP G +G  GPPGP   PGE G +
Sbjct: 877  GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGP---PGERGPQ 933

Query: 137  GPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCP----------------- 179
            GP+G  G  GP GPPGPPGK G PG   G  G   F   T  P                 
Sbjct: 934  GPQGPVGFPGPKGPPGPPGKDGLPGH-PGQRGETGFQGKTGPPGPGGVVGPQGPTGETGP 992

Query: 180  ------PGMKGPPGLQGVKGHAGKRGILGDPGHQG---KPGPKGDVGASGEQGIPGPPGP 230
                  PG  GPPG QG+ G AGK G  GDPG QG   K GP G  G  GE+G+PG  G 
Sbjct: 993  IGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA 1052

Query: 231  QGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPG---- 286
             G++G  G  GP G  G  G +G  G  G  G PG  GP+GPPG AGEKG  G  G    
Sbjct: 1053 PGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGP 1112

Query: 287  -----IRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQ 341
                 ++GP G+ GP G  G PG +G  G  G PG KGS G  G+ G PG  GL G  G 
Sbjct: 1113 AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGA 1172

Query: 342  PGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGP 401
            PG  GG G+ G  G QG+ G  G  G  G PGP G IG QG+ G  G++GE G VG  GP
Sbjct: 1173 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1232

Query: 402  QGRQGPKGEQGPPGIPGPQGLPGVKG------DKGSPGKTGPRGKVGDPGVAGLPGEKGE 455
             G  GP+G QGP G  GPQG PG  G      +KG PG+ G  G  G+ GV G  GE+GE
Sbjct: 1233 PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGE 1292

Query: 456  KGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGV--------- 506
            KGE+G PG  G  G +G PG  GP G+ G  G  G PGPPG  G AG  GV         
Sbjct: 1293 KGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGD 1352

Query: 507  ---PGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGP 563
               PG PG  G  G                + +  E     +  A G  G  GP GP GP
Sbjct: 1353 PGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGP 1412

Query: 564  PGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGE---KGDPGEVG-RGHPGMPGP 619
             G PG +G  G PGP G  G+ GA GQ G  GP G  G    KGDPG  G +GHPG+ G 
Sbjct: 1413 AGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGL 1472

Query: 620  PGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGL------PGPVGLPGFCEPAACLGAS 673
             G PG  G  G    G  G +GSPGA G+ G PG       PGP GLPG   P    G++
Sbjct: 1473 IGPPGEQGEKGD--RGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1530

Query: 674  AYASAR----LTEPGSIKGP 689
              A  +    L  P    GP
Sbjct: 1531 GPAGQKGDSGLPGPPGSPGP 1550



 Score =  531 bits (1369), Expect = e-151
 Identities = 309/681 (45%), Positives = 352/681 (51%), Gaps = 61/681 (8%)

Query: 25   IRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDG------PDG 78
            + G PG  G  GP G  G PG  G +G+ G  G AG PGP+G+ G  GP G      P G
Sbjct: 851  VPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTG 910

Query: 79   KPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGP 138
            KPG  G +G  G PGP   PG +G  G  GP G PGP   GPPGPPG  GLPG  G RG 
Sbjct: 911  KPGPKGTSGGDGPPGP---PGERGPQGPQGPVGFPGP--KGPPGPPGKDGLPGHPGQRGE 965

Query: 139  ---KGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHA 195
               +G  GP GP G  GP G  G  G I G  G           PG  GPPG QG+ G A
Sbjct: 966  TGFQGKTGPPGPGGVVGPQGPTGETGPI-GERGH----------PGPPGPPGEQGLPGAA 1014

Query: 196  GKRGILGDPGHQ---GKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYK 252
            GK G  GDPG Q   GK GP G  G  GE+G+PG  G  G++G  G  GP G  G  G +
Sbjct: 1015 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1074

Query: 253  GMVGAIGATGPPGEEGPRGPPGRAGEK---------GDEGSPGIRGPQGITGPKGATGPP 303
            G  G  G  G PG  GP+GPPG AGEK         G  G  G++GP G+ GP G  G P
Sbjct: 1075 GSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSP 1134

Query: 304  GINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFS 363
            G +G  G  G PG KGS G  G+ G PG  GL G  G PG  GG G+ G  G QG+ G  
Sbjct: 1135 GEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK 1194

Query: 364  GPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLP 423
            G  G  G PGP G IG QG+ G  G++GE G VG  GP G  GP+G QGP G  GPQG P
Sbjct: 1195 GDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPP 1254

Query: 424  GV------KGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYP 477
            G        G+KG PG+ G  G  G+ GV G  GE+GEKGE+G PG  G  G +G PG  
Sbjct: 1255 GSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDD 1314

Query: 478  GPSGDAGAPGVQGYPGPPGPRGLAGNRGV------------PGQPGRQGVEGRDATDQHI 525
            GP G+ G  G  G PGPPG  G AG  GV            PG PG  G  G        
Sbjct: 1315 GPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKR 1374

Query: 526  VDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIV 585
                    + +  E     +  A G  G  GP GP GP G PG +G  G PGP G  G+ 
Sbjct: 1375 GPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLP 1434

Query: 586  GAVGQIGNTGPKGK---RGEKGDPGEVG-RGHPGMPGPPGIPGLPGRPGQAINGKDGDRG 641
            GA GQ G  GP G     G KGDPG  G +GHPG+ G  G PG  G  G    G  G +G
Sbjct: 1435 GAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGD--RGLPGTQG 1492

Query: 642  SPGAPGEAGRPGLPGPVGLPG 662
            SPGA G+ G PG  GP+G PG
Sbjct: 1493 SPGAKGDGGIPGPAGPLGPPG 1513



 Score =  520 bits (1339), Expect = e-147
 Identities = 322/748 (43%), Positives = 372/748 (49%), Gaps = 94/748 (12%)

Query: 25   IRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDG 84
            +RGPPG  G  G PGP G PGS G  G++G PG  GP G +G PG  G  G  G+PG DG
Sbjct: 539  LRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADG 598

Query: 85   LTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP-GFAGPPGPPGPVGLPGEIGIRGPKGDPG 143
              G  GEPG  G  G  G PGLPG  G  G  G  GPPGPPG  G+ GE G  GP+G PG
Sbjct: 599  GRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPG 658

Query: 144  PDGPS---GPPGPPGKPGRPGT--IQGLEGSADFLCPTN--CPPGMKGPPGLQGV----- 191
              GP    GP G PG PG+PG   + G  G    + P     PPG +G PG QG+     
Sbjct: 659  EAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 718

Query: 192  -------KGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYP------- 237
                   KG  GK G+ G PG  G PG  G  G SGE+G  GPPGPQG  GYP       
Sbjct: 719  PIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKG 778

Query: 238  -----GMAGPKGETGPHGY---------KGMVGAIGATGPPGEEGPRGPPGR-------- 275
                 G+ G KGE G  G+         KG  G +G  GP GE+GP GP GR        
Sbjct: 779  ADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 838

Query: 276  ----AGEKGDEGSPGIRGPQGITGPKGATGPPGINGKD------GTPGTPGMKGSAGQAG 325
                AGEKG  G PG+ G  G  GPKG+TG PG  G +      G  G PG +G  G  G
Sbjct: 839  PSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTG 898

Query: 326  QPGSPGHQGLAGVPGQPGTKGG------PGDQGEPGPQGLPGF------SGPPGKE---G 370
              GS G +G  G PG  GT GG      PG++G  GPQG  GF       GPPGK+   G
Sbjct: 899  PRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPG 958

Query: 371  EPGPRGEI---------GPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQG 421
             PG RGE          GP G++G +G  GE GP+G+ G  G  GP GEQG PG  G +G
Sbjct: 959  HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEG 1018

Query: 422  LPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSG 481
              G  G +G  GK GP G  G PG  GLPG +G  G  G  GP+G  G  G PG  G +G
Sbjct: 1019 AKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAG 1078

Query: 482  DAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVA 541
             AG  G+ G PGP GP G AG +G PG+ G QG  GRD     +       L        
Sbjct: 1079 TAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPV------GLPGPAGPAG 1132

Query: 542  VSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRG 601
               +    G +G  G  G  G  G  G  GP G  GP G PGI G  G+ G  G +G  G
Sbjct: 1133 SPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFG 1192

Query: 602  EKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLP 661
            +KGD G   RG PG PGP G+ GLPG PG+   G++GD G  G PG  G  G  GP G  
Sbjct: 1193 QKGDEG--ARGFPGPPGPIGLQGLPGPPGE--KGENGDVGPMGPPGPPGPRGPQGPNGAD 1248

Query: 662  GFCEPAACLGASAYASARLTEPGSIKGP 689
            G   P   +G S        EPG    P
Sbjct: 1249 GPQGPPGSVG-SVGGVGEKGEPGEAGNP 1275



 Score =  507 bits (1305), Expect = e-143
 Identities = 300/693 (43%), Positives = 354/693 (51%), Gaps = 110/693 (15%)

Query: 27   GPPGERGP---------PGPPGPPGVPGSDGIDG------DNGPPGKAGPPGP------- 64
            GPPGERGP         PGP GPPG PG DG+ G      + G  GK GPPGP       
Sbjct: 925  GPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQ 984

Query: 65   -----------KGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGL---PGPP 110
                       +G PG  GP G  G PG  G  GAKG+PGP GI G  G  GL   PG  
Sbjct: 985  GPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGER 1044

Query: 111  GLPGP-------GFAGPPGPPGPVGLPGE---IGIRGPKGDPGPDGPSGPPGPPGKPGRP 160
            GLPG        G  GP GPPGPVG PGE    G  GP G PG  GP GPPGP G+ G P
Sbjct: 1045 GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1104

Query: 161  GTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASG 220
            G  +G +G A          G++GP GL G  G AG  G  GD G  G+PG KG  G  G
Sbjct: 1105 GE-KGPQGPAG-------RDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKG 1156

Query: 221  EQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVG------AIGATGPPGEEGPRGPPG 274
            E G PGPPG QG  G PG+AG  GE GP G +GM G      A G  GPPG  G +G PG
Sbjct: 1157 ENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPG 1216

Query: 275  RAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPG---SPG 331
              GEKG+ G  G  GP G  GP+G  GP G +G  G PG+ G  G  G+ G+PG   +PG
Sbjct: 1217 PPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPG 1276

Query: 332  HQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEG------------EPGPRGEIG 379
              G AGV G  G +G  G+ G PG  G PG  GPPG +G            +PGP GE G
Sbjct: 1277 PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1336

Query: 380  PQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRG 439
            P G  G  GD+GE G  GQPGP G   P GE GPPG PG +G PG  G +G  G+ G +G
Sbjct: 1337 PAGQDGVGGDKGEDGDPGQPGPPG---PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKG 1393

Query: 440  KVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRG 499
            + G  G  G  G  G +G +G+PGP+G +G+      PGP G+ G PG  G  GPPGP G
Sbjct: 1394 EAGAEGPPGKTGPVGPQGPAGKPGPEGLRGI------PGPVGEQGLPGAAGQDGPPGPMG 1447

Query: 500  LAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPG 559
              G  G+ G PG +G +G               L   +       ++   G  G  G PG
Sbjct: 1448 PPGLPGLKGDPGSKGEKGHPG------------LIGLIGPPGEQGEKGDRGLPGTQGSPG 1495

Query: 560  PPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGP 619
              G  G PG  GP G PGP G+PG  G  G  G+TGP G++G+            G+PGP
Sbjct: 1496 AKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDS-----------GLPGP 1544

Query: 620  PGIPGLPG---RPGQAINGKDGDRGSPGAPGEA 649
            PG PG PG   +P   ++ K   R + G   +A
Sbjct: 1545 PGSPGPPGEVIQPLPILSSKKTRRHTEGMQADA 1577



 Score =  500 bits (1287), Expect = e-141
 Identities = 305/722 (42%), Positives = 360/722 (49%), Gaps = 98/722 (13%)

Query: 33   GPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEP 92
            GPPGP GP G+ G         PPG  GP GP G+PG  GP G  G PG DGL    G P
Sbjct: 454  GPPGPAGPAGIMG---------PPGLQGPTGPPGDPGDRGPPGRPGLPGADGLP---GPP 501

Query: 93   GPM-GIPGVKGQPGLPGPPGLPGPGFA------------GPPGP------PGPVGLPGEI 133
            G M  +P   G  G  GP        A            GPPGP      PGPVG PG  
Sbjct: 502  GTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSS 561

Query: 134  GIRGPKGDPGPDGP---SGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQG 190
            G +G  GDPGP GP    GPPGP GKPG+ G   G +G            GM G PG +G
Sbjct: 562  GAKGESGDPGPQGPRGVQGPPGPTGKPGKRGR-PGADGGR----------GMPGEPGAKG 610

Query: 191  VKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPH- 249
             +G  G  G+ GD GH+G+ GP+G  G  G+ G+ G  G  G RG PG AGP+G  GP  
Sbjct: 611  DRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRG 670

Query: 250  -----GYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGP-- 302
                 G  GM G  G  GP G  GP+G PG  G++G+ G  G+ GPQG  GP G  GP  
Sbjct: 671  TPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQG 730

Query: 303  ----PGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGG------PGDQG 352
                 G+ G DG PG PG +G +G+ G  G PG QG  G PG  G KG        G +G
Sbjct: 731  KPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKG 790

Query: 353  EPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQG 412
            E G  G PGF G  G +G+ G  G+IGP+G  G +G +G  GP G PGP G+ G KG+ G
Sbjct: 791  EKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLG 850

Query: 413  PPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGE------------KGESG 460
             PG+PG  G  G KG  G PG  G  G+ G  GVAG PG +G+            +G +G
Sbjct: 851  VPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTG 910

Query: 461  EPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDA 520
            +PGPKG  G  G PG PG  G  G  G  G+PGP GP G  G  G+PG PG++G  G   
Sbjct: 911  KPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 970

Query: 521  TDQHIVDVALKMLQEQLAEVAVSAKR-----------EAL-GAVGMMGPPGPPGPPGYPG 568
                     +   Q    E     +R           + L GA G  G  G PGP G  G
Sbjct: 971  KTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISG 1030

Query: 569  KQGP---HGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGL 625
            K GP    G PG RG+PG  GA G  G  GP+G  G  G PGE  RG  G  GP G+PG 
Sbjct: 1031 KDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGE--RGSAGTAGPIGLPGR 1088

Query: 626  PGRPGQAINGKDGDRGSP---GAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASARLTE 682
            PG  G    G  G++G+P   G  G AGR G+ GPVGLPG   PA   G        + E
Sbjct: 1089 PGPQGPP--GPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG-DKGEIGE 1145

Query: 683  PG 684
            PG
Sbjct: 1146 PG 1147



 Score =  313 bits (802), Expect = 3e-85
 Identities = 177/388 (45%), Positives = 206/388 (53%), Gaps = 52/388 (13%)

Query: 20   LALAQIRGPPGER---------GPPGPPGPPGVPGSDGIDGDNGPPGKAGP---PGPKGE 67
            + L  + GPPGE+         GPPGPPGP G  G +G DG  GPPG  G     G KGE
Sbjct: 1209 IGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1268

Query: 68   PGKAGPDGPDGKPGIDGLTGAKGE------PGPMGIPGVKGQPGLPGPPGLPGP-GFAGP 120
            PG+AG  GP G+ G+ G  G +GE      PG  G PG KG PG  GP G PGP GF G 
Sbjct: 1269 PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD 1328

Query: 121  PGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPP 180
            PGPPG  G  G+ G+ G KG+ G  G  GPPGP G+ G PG                 PP
Sbjct: 1329 PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG-----------------PP 1371

Query: 181  GMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMA 240
            G +GPPG  G +G  G++G  G+ G +G PG  G V   G QG  G PGP+G+RG P   
Sbjct: 1372 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPV---GPQGPAGKPGPEGLRGIP--- 1425

Query: 241  GPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGAT 300
                  GP G +G+ GA G  GPP   GP GPPG  G KGD GS G +G  G+ G  G  
Sbjct: 1426 ------GPVGEQGLPGAAGQDGPP---GPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPP 1476

Query: 301  GPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLP 360
            G  G  G  G PGT G  G+ G  G PG  G  G  G PG PG +G  G++G  GP G  
Sbjct: 1477 GEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQK 1536

Query: 361  GFSGPPGKEGEPGPRGE-IGPQGIMGQK 387
            G SG PG  G PGP GE I P  I+  K
Sbjct: 1537 GDSGLPGPPGSPGPPGEVIQPLPILSSK 1564


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  539 bits (1388), Expect = e-153
 Identities = 309/672 (45%), Positives = 354/672 (52%), Gaps = 53/672 (7%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
            GP G RG  GP G PG  G+ G DG  GPPG+ GP GP+G  G  GP GP G PG DGL 
Sbjct: 847  GPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLP 906

Query: 87   GAKGEPGPMGIPGVKGQPGLPGPPGLPGP-------------GFAGPPGPPGPVGLPGEI 133
            G    PG  G  G +G+ G PGP G+ GP             G  GPPGPPG  GLPG  
Sbjct: 907  G---HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 963

Query: 134  GIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKG 193
            G  G KGDPGP G SG  GP G  G PG  +GL             PG +G PGL+G +G
Sbjct: 964  GKEGAKGDPGPQGISGKDGPAGLRGFPGE-RGL-------------PGAQGAPGLKGGEG 1009

Query: 194  HAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKG 253
              G  G +G PG +G  G  G +G  G  G  GPPGP G +G PG  GP+G  G  G +G
Sbjct: 1010 PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQG 1069

Query: 254  MVGAIGATGP---PGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDG 310
             VG  G  GP   PGE+G +G  G  G+KG +G  G  GP G  G +G  G PGI G DG
Sbjct: 1070 PVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1129

Query: 311  TPGTPGMKGSAGQAGQ------PGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSG 364
             PG  G +G  GQ G       PG PG  GL G+PG PG KG  GD G  GP G PG  G
Sbjct: 1130 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRG 1189

Query: 365  PPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQG---PKGEQGPPGIPGPQG 421
            P G  G  GP+G  G  G +G  G++GE G  G PGP G  G   PKGE+G  G  GP G
Sbjct: 1190 PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPG 1249

Query: 422  LPGVKGDKGSPGKTGPRGK---VGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPG 478
              G  G KG PG  GP+G    VG PG  G PGE G  G+ G  G KG+ G  G+PG PG
Sbjct: 1250 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1309

Query: 479  PSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHI--VDVALKMLQEQ 536
            PSG+AG PG  G  GPPG  G  G +G  G  G  G EG       +     A K   E 
Sbjct: 1310 PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEG 1369

Query: 537  LAEVAVSAKREAL-GAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTG 595
            L  +      + L GA G  GPPGP GPPG PG +G  G  G +G PG++G +G  G  G
Sbjct: 1370 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG 1429

Query: 596  PKGKRG---EKGDPGEVGRGH-PGMPGPPGIPGLPGRPG-QAINGKDGDRGSPGAPGEAG 650
             KG RG    +G PG  G G  PG  GP G PG PG PG Q   G  G  G  G  G++G
Sbjct: 1430 EKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSG 1489

Query: 651  RPGLPGPVGLPG 662
             PG PG  G PG
Sbjct: 1490 LPGPPGSPGPPG 1501



 Score =  536 bits (1380), Expect = e-152
 Identities = 326/737 (44%), Positives = 375/737 (50%), Gaps = 118/737 (16%)

Query: 26   RGPPGERGPPGPPGPPGVPGSDGIDGDNGP---PGKAGPPGPKGEPGKAGPDGPDGKPGI 82
            +G  GERGP GPPGPPG  G  G DG+ GP   PG+AGP G  G  G  G  G  G  G+
Sbjct: 573  KGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV 632

Query: 83   DGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP-GFAGPPGPPGPVGLPGEIGI---RGP 138
            DG  G KG  GP G PG  GQ G PGP GLPGP G  GPPG  GP G PG  G+    GP
Sbjct: 633  DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGP 692

Query: 139  KGDPGPDGPS------GPPGPPGKPGRPGT--------IQGLEGSADFLCPTNCPPGMKG 184
             G PG +G S      GPPGP G  G PG         ++GL+GS          PG KG
Sbjct: 693  PGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGF-PGFKG 751

Query: 185  PPGLQGVKGHAGK---RGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAG 241
              GL+G +G  G+   RG  G  G +G+ GP GD G SG+ G  G  G  G+ GYPG  G
Sbjct: 752  DMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG 811

Query: 242  PKGETGPHGYKGMVGAIGA---------------TGPPGEEGPRGPPGRAGEKGDEGS-- 284
            PKG TG  G+ G  G  GA               TGP G  G RGP G+ G KG  G   
Sbjct: 812  PKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDG 871

Query: 285  ----PGIRGPQGITGP---KGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAG 337
                PG RGPQG  GP    G  GPPG  GKDG PG PG +G  G  G+ G PG  G+ G
Sbjct: 872  PPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVG 931

Query: 338  VPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQ----------- 386
              G  G  G  G++G PGP G PG  G PG  G+ G +G+ GPQGI G+           
Sbjct: 932  PQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPG 991

Query: 387  ----------------KGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKG 430
                            +G QG  GPVG PG +G  G  G  G PG PGPQG PG  G+KG
Sbjct: 992  ERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKG 1051

Query: 431  SPGKTGPRGKVGDPGV------------AGLPGEKGEKGESGEPGPKGQQGVRGEPGYPG 478
            +PG+ GP+G  G  GV            AG PGE G+KGE GEPG KG +G +GE G PG
Sbjct: 1052 APGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPG 1111

Query: 479  P---SGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQE 535
            P    G  GAPG+ G  G PGPRG  G  G  G  G +G  G          + L+ L  
Sbjct: 1112 PPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG------PIGLQGLPG 1165

Query: 536  QLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTG 595
               E          G  G +GP GPPGPPG  G QGP+G  GP+G PG VG+VG +G  G
Sbjct: 1166 PPGE---------KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKG 1216

Query: 596  PKGKRGEKGDPGEVG-------RGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGA--- 645
              G+ G  G PGE G       RG  G  GPPG  G PG  G    G DG +G+PG    
Sbjct: 1217 EPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPP--GDDGPKGNPGPVGF 1274

Query: 646  PGEAGRPGLPGPVGLPG 662
            PG+ G PG PGP G  G
Sbjct: 1275 PGDPGPPGEPGPAGQDG 1291



 Score =  533 bits (1373), Expect = e-151
 Identities = 323/740 (43%), Positives = 365/740 (49%), Gaps = 83/740 (11%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
            GP GE GP GP G  G  G  G  G  G  GK G PG  G PG+ GP G  G PG  G  
Sbjct: 766  GPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGAN 825

Query: 87   GAKGEPGPMGIPGVKGQPG---------LPGPPGLPGP-GFAGPPGPPGPVGLPGEIGIR 136
            G KG  G  G PG +GQ G           GP G PGP G +G  GPPGP   PGE G +
Sbjct: 826  GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGP---PGERGPQ 882

Query: 137  GPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCP----------------- 179
            GP+G  G  GP GPPGPPGK G PG   G  G   F   T  P                 
Sbjct: 883  GPQGPVGFPGPKGPPGPPGKDGLPGH-PGQRGETGFQGKTGPPGPGGVVGPQGPTGETGP 941

Query: 180  ------PGMKGPPGLQGVKGHAGKRGILGDPGHQG---KPGPKGDVGASGEQGIPGPPGP 230
                  PG  GPPG QG+ G AGK G  GDPG QG   K GP G  G  GE+G+PG  G 
Sbjct: 942  IGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA 1001

Query: 231  QGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPG---- 286
             G++G  G  GP G  G  G +G  G  G  G PG  GP+GPPG AGEKG  G  G    
Sbjct: 1002 PGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGP 1061

Query: 287  -----IRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQ 341
                 ++GP G+ GP G  G PG +G  G  G PG KGS G  G+ G PG  GL G  G 
Sbjct: 1062 AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGA 1121

Query: 342  PGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGP 401
            PG  GG G+ G  G QG+ G  G  G  G PGP G IG QG+ G  G++GE G VG  GP
Sbjct: 1122 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1181

Query: 402  QGRQGPKGEQGPPGIPGPQGLPGVKG------DKGSPGKTGPRGKVGDPGVAGLPGEKGE 455
             G  GP+G QGP G  GPQG PG  G      +KG PG+ G  G  G+ GV G  GE+GE
Sbjct: 1182 PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGE 1241

Query: 456  KGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGV--------- 506
            KGE+G PG  G  G +G PG  GP G+ G  G  G PGPPG  G AG  GV         
Sbjct: 1242 KGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGD 1301

Query: 507  ---PGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGP 563
               PG PG  G  G                + +  E     +  A G  G  GP GP GP
Sbjct: 1302 PGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGP 1361

Query: 564  PGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGE---KGDPGEVG-RGHPGMPGP 619
             G PG +G  G PGP G  G+ GA GQ G  GP G  G    KGDPG  G +GHPG+ G 
Sbjct: 1362 AGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGL 1421

Query: 620  PGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGL------PGPVGLPGFCEPAACLGAS 673
             G PG  G  G    G  G +GSPGA G+ G PG       PGP GLPG   P    G++
Sbjct: 1422 IGPPGEQGEKGD--RGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1479

Query: 674  AYASAR----LTEPGSIKGP 689
              A  +    L  P    GP
Sbjct: 1480 GPAGQKGDSGLPGPPGSPGP 1499



 Score =  531 bits (1369), Expect = e-151
 Identities = 309/681 (45%), Positives = 352/681 (51%), Gaps = 61/681 (8%)

Query: 25   IRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDG------PDG 78
            + G PG  G  GP G  G PG  G +G+ G  G AG PGP+G+ G  GP G      P G
Sbjct: 800  VPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTG 859

Query: 79   KPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGP 138
            KPG  G +G  G PGP   PG +G  G  GP G PGP   GPPGPPG  GLPG  G RG 
Sbjct: 860  KPGPKGTSGGDGPPGP---PGERGPQGPQGPVGFPGP--KGPPGPPGKDGLPGHPGQRGE 914

Query: 139  ---KGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHA 195
               +G  GP GP G  GP G  G  G I G  G           PG  GPPG QG+ G A
Sbjct: 915  TGFQGKTGPPGPGGVVGPQGPTGETGPI-GERGH----------PGPPGPPGEQGLPGAA 963

Query: 196  GKRGILGDPGHQ---GKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYK 252
            GK G  GDPG Q   GK GP G  G  GE+G+PG  G  G++G  G  GP G  G  G +
Sbjct: 964  GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1023

Query: 253  GMVGAIGATGPPGEEGPRGPPGRAGEK---------GDEGSPGIRGPQGITGPKGATGPP 303
            G  G  G  G PG  GP+GPPG AGEK         G  G  G++GP G+ GP G  G P
Sbjct: 1024 GSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSP 1083

Query: 304  GINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFS 363
            G +G  G  G PG KGS G  G+ G PG  GL G  G PG  GG G+ G  G QG+ G  
Sbjct: 1084 GEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK 1143

Query: 364  GPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLP 423
            G  G  G PGP G IG QG+ G  G++GE G VG  GP G  GP+G QGP G  GPQG P
Sbjct: 1144 GDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPP 1203

Query: 424  GV------KGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYP 477
            G        G+KG PG+ G  G  G+ GV G  GE+GEKGE+G PG  G  G +G PG  
Sbjct: 1204 GSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDD 1263

Query: 478  GPSGDAGAPGVQGYPGPPGPRGLAGNRGV------------PGQPGRQGVEGRDATDQHI 525
            GP G+ G  G  G PGPPG  G AG  GV            PG PG  G  G        
Sbjct: 1264 GPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKR 1323

Query: 526  VDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIV 585
                    + +  E     +  A G  G  GP GP GP G PG +G  G PGP G  G+ 
Sbjct: 1324 GPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLP 1383

Query: 586  GAVGQIGNTGPKGK---RGEKGDPGEVG-RGHPGMPGPPGIPGLPGRPGQAINGKDGDRG 641
            GA GQ G  GP G     G KGDPG  G +GHPG+ G  G PG  G  G    G  G +G
Sbjct: 1384 GAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGD--RGLPGTQG 1441

Query: 642  SPGAPGEAGRPGLPGPVGLPG 662
            SPGA G+ G PG  GP+G PG
Sbjct: 1442 SPGAKGDGGIPGPAGPLGPPG 1462



 Score =  520 bits (1339), Expect = e-147
 Identities = 322/748 (43%), Positives = 372/748 (49%), Gaps = 94/748 (12%)

Query: 25   IRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDG 84
            +RGPPG  G  G PGP G PGS G  G++G PG  GP G +G PG  G  G  G+PG DG
Sbjct: 488  LRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADG 547

Query: 85   LTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP-GFAGPPGPPGPVGLPGEIGIRGPKGDPG 143
              G  GEPG  G  G  G PGLPG  G  G  G  GPPGPPG  G+ GE G  GP+G PG
Sbjct: 548  GRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPG 607

Query: 144  PDGPS---GPPGPPGKPGRPGT--IQGLEGSADFLCPTN--CPPGMKGPPGLQGV----- 191
              GP    GP G PG PG+PG   + G  G    + P     PPG +G PG QG+     
Sbjct: 608  EAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 667

Query: 192  -------KGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYP------- 237
                   KG  GK G+ G PG  G PG  G  G SGE+G  GPPGPQG  GYP       
Sbjct: 668  PIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKG 727

Query: 238  -----GMAGPKGETGPHGY---------KGMVGAIGATGPPGEEGPRGPPGR-------- 275
                 G+ G KGE G  G+         KG  G +G  GP GE+GP GP GR        
Sbjct: 728  ADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 787

Query: 276  ----AGEKGDEGSPGIRGPQGITGPKGATGPPGINGKD------GTPGTPGMKGSAGQAG 325
                AGEKG  G PG+ G  G  GPKG+TG PG  G +      G  G PG +G  G  G
Sbjct: 788  PSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTG 847

Query: 326  QPGSPGHQGLAGVPGQPGTKGG------PGDQGEPGPQGLPGF------SGPPGKE---G 370
              GS G +G  G PG  GT GG      PG++G  GPQG  GF       GPPGK+   G
Sbjct: 848  PRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPG 907

Query: 371  EPGPRGEI---------GPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQG 421
             PG RGE          GP G++G +G  GE GP+G+ G  G  GP GEQG PG  G +G
Sbjct: 908  HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEG 967

Query: 422  LPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSG 481
              G  G +G  GK GP G  G PG  GLPG +G  G  G  GP+G  G  G PG  G +G
Sbjct: 968  AKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAG 1027

Query: 482  DAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVA 541
             AG  G+ G PGP GP G AG +G PG+ G QG  GRD     +       L        
Sbjct: 1028 TAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPV------GLPGPAGPAG 1081

Query: 542  VSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRG 601
               +    G +G  G  G  G  G  G  GP G  GP G PGI G  G+ G  G +G  G
Sbjct: 1082 SPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFG 1141

Query: 602  EKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLP 661
            +KGD G   RG PG PGP G+ GLPG PG+   G++GD G  G PG  G  G  GP G  
Sbjct: 1142 QKGDEG--ARGFPGPPGPIGLQGLPGPPGE--KGENGDVGPMGPPGPPGPRGPQGPNGAD 1197

Query: 662  GFCEPAACLGASAYASARLTEPGSIKGP 689
            G   P   +G S        EPG    P
Sbjct: 1198 GPQGPPGSVG-SVGGVGEKGEPGEAGNP 1224



 Score =  507 bits (1305), Expect = e-143
 Identities = 300/693 (43%), Positives = 354/693 (51%), Gaps = 110/693 (15%)

Query: 27   GPPGERGP---------PGPPGPPGVPGSDGIDG------DNGPPGKAGPPGP------- 64
            GPPGERGP         PGP GPPG PG DG+ G      + G  GK GPPGP       
Sbjct: 874  GPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQ 933

Query: 65   -----------KGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGL---PGPP 110
                       +G PG  GP G  G PG  G  GAKG+PGP GI G  G  GL   PG  
Sbjct: 934  GPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGER 993

Query: 111  GLPGP-------GFAGPPGPPGPVGLPGE---IGIRGPKGDPGPDGPSGPPGPPGKPGRP 160
            GLPG        G  GP GPPGPVG PGE    G  GP G PG  GP GPPGP G+ G P
Sbjct: 994  GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1053

Query: 161  GTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASG 220
            G  +G +G A          G++GP GL G  G AG  G  GD G  G+PG KG  G  G
Sbjct: 1054 GE-KGPQGPAG-------RDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKG 1105

Query: 221  EQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVG------AIGATGPPGEEGPRGPPG 274
            E G PGPPG QG  G PG+AG  GE GP G +GM G      A G  GPPG  G +G PG
Sbjct: 1106 ENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPG 1165

Query: 275  RAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPG---SPG 331
              GEKG+ G  G  GP G  GP+G  GP G +G  G PG+ G  G  G+ G+PG   +PG
Sbjct: 1166 PPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPG 1225

Query: 332  HQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEG------------EPGPRGEIG 379
              G AGV G  G +G  G+ G PG  G PG  GPPG +G            +PGP GE G
Sbjct: 1226 PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1285

Query: 380  PQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRG 439
            P G  G  GD+GE G  GQPGP G   P GE GPPG PG +G PG  G +G  G+ G +G
Sbjct: 1286 PAGQDGVGGDKGEDGDPGQPGPPG---PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKG 1342

Query: 440  KVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRG 499
            + G  G  G  G  G +G +G+PGP+G +G+      PGP G+ G PG  G  GPPGP G
Sbjct: 1343 EAGAEGPPGKTGPVGPQGPAGKPGPEGLRGI------PGPVGEQGLPGAAGQDGPPGPMG 1396

Query: 500  LAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPG 559
              G  G+ G PG +G +G               L   +       ++   G  G  G PG
Sbjct: 1397 PPGLPGLKGDPGSKGEKGHPG------------LIGLIGPPGEQGEKGDRGLPGTQGSPG 1444

Query: 560  PPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGP 619
              G  G PG  GP G PGP G+PG  G  G  G+TGP G++G+            G+PGP
Sbjct: 1445 AKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDS-----------GLPGP 1493

Query: 620  PGIPGLPG---RPGQAINGKDGDRGSPGAPGEA 649
            PG PG PG   +P   ++ K   R + G   +A
Sbjct: 1494 PGSPGPPGEVIQPLPILSSKKTRRHTEGMQADA 1526



 Score =  500 bits (1287), Expect = e-141
 Identities = 305/722 (42%), Positives = 360/722 (49%), Gaps = 98/722 (13%)

Query: 33   GPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEP 92
            GPPGP GP G+ G         PPG  GP GP G+PG  GP G  G PG DGL    G P
Sbjct: 403  GPPGPAGPAGIMG---------PPGLQGPTGPPGDPGDRGPPGRPGLPGADGLP---GPP 450

Query: 93   GPM-GIPGVKGQPGLPGPPGLPGPGFA------------GPPGP------PGPVGLPGEI 133
            G M  +P   G  G  GP        A            GPPGP      PGPVG PG  
Sbjct: 451  GTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSS 510

Query: 134  GIRGPKGDPGPDGP---SGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQG 190
            G +G  GDPGP GP    GPPGP GKPG+ G   G +G            GM G PG +G
Sbjct: 511  GAKGESGDPGPQGPRGVQGPPGPTGKPGKRGR-PGADGGR----------GMPGEPGAKG 559

Query: 191  VKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPH- 249
             +G  G  G+ GD GH+G+ GP+G  G  G+ G+ G  G  G RG PG AGP+G  GP  
Sbjct: 560  DRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRG 619

Query: 250  -----GYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGP-- 302
                 G  GM G  G  GP G  GP+G PG  G++G+ G  G+ GPQG  GP G  GP  
Sbjct: 620  TPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQG 679

Query: 303  ----PGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGG------PGDQG 352
                 G+ G DG PG PG +G +G+ G  G PG QG  G PG  G KG        G +G
Sbjct: 680  KPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKG 739

Query: 353  EPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQG 412
            E G  G PGF G  G +G+ G  G+IGP+G  G +G +G  GP G PGP G+ G KG+ G
Sbjct: 740  EKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLG 799

Query: 413  PPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGE------------KGESG 460
             PG+PG  G  G KG  G PG  G  G+ G  GVAG PG +G+            +G +G
Sbjct: 800  VPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTG 859

Query: 461  EPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDA 520
            +PGPKG  G  G PG PG  G  G  G  G+PGP GP G  G  G+PG PG++G  G   
Sbjct: 860  KPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 919

Query: 521  TDQHIVDVALKMLQEQLAEVAVSAKR-----------EAL-GAVGMMGPPGPPGPPGYPG 568
                     +   Q    E     +R           + L GA G  G  G PGP G  G
Sbjct: 920  KTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISG 979

Query: 569  KQGP---HGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGL 625
            K GP    G PG RG+PG  GA G  G  GP+G  G  G PGE  RG  G  GP G+PG 
Sbjct: 980  KDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGE--RGSAGTAGPIGLPGR 1037

Query: 626  PGRPGQAINGKDGDRGSP---GAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASARLTE 682
            PG  G    G  G++G+P   G  G AGR G+ GPVGLPG   PA   G        + E
Sbjct: 1038 PGPQGPP--GPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG-DKGEIGE 1094

Query: 683  PG 684
            PG
Sbjct: 1095 PG 1096



 Score =  313 bits (802), Expect = 3e-85
 Identities = 177/388 (45%), Positives = 206/388 (53%), Gaps = 52/388 (13%)

Query: 20   LALAQIRGPPGER---------GPPGPPGPPGVPGSDGIDGDNGPPGKAGP---PGPKGE 67
            + L  + GPPGE+         GPPGPPGP G  G +G DG  GPPG  G     G KGE
Sbjct: 1158 IGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1217

Query: 68   PGKAGPDGPDGKPGIDGLTGAKGE------PGPMGIPGVKGQPGLPGPPGLPGP-GFAGP 120
            PG+AG  GP G+ G+ G  G +GE      PG  G PG KG PG  GP G PGP GF G 
Sbjct: 1218 PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD 1277

Query: 121  PGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPP 180
            PGPPG  G  G+ G+ G KG+ G  G  GPPGP G+ G PG                 PP
Sbjct: 1278 PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG-----------------PP 1320

Query: 181  GMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMA 240
            G +GPPG  G +G  G++G  G+ G +G PG  G V   G QG  G PGP+G+RG P   
Sbjct: 1321 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPV---GPQGPAGKPGPEGLRGIP--- 1374

Query: 241  GPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGAT 300
                  GP G +G+ GA G  GPP   GP GPPG  G KGD GS G +G  G+ G  G  
Sbjct: 1375 ------GPVGEQGLPGAAGQDGPP---GPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPP 1425

Query: 301  GPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLP 360
            G  G  G  G PGT G  G+ G  G PG  G  G  G PG PG +G  G++G  GP G  
Sbjct: 1426 GEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQK 1485

Query: 361  GFSGPPGKEGEPGPRGE-IGPQGIMGQK 387
            G SG PG  G PGP GE I P  I+  K
Sbjct: 1486 GDSGLPGPPGSPGPPGEVIQPLPILSSK 1513


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  539 bits (1388), Expect = e-153
 Identities = 309/672 (45%), Positives = 354/672 (52%), Gaps = 53/672 (7%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
            GP G RG  GP G PG  G+ G DG  GPPG+ GP GP+G  G  GP GP G PG DGL 
Sbjct: 886  GPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLP 945

Query: 87   GAKGEPGPMGIPGVKGQPGLPGPPGLPGP-------------GFAGPPGPPGPVGLPGEI 133
            G    PG  G  G +G+ G PGP G+ GP             G  GPPGPPG  GLPG  
Sbjct: 946  G---HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 1002

Query: 134  GIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKG 193
            G  G KGDPGP G SG  GP G  G PG  +GL             PG +G PGL+G +G
Sbjct: 1003 GKEGAKGDPGPQGISGKDGPAGLRGFPGE-RGL-------------PGAQGAPGLKGGEG 1048

Query: 194  HAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKG 253
              G  G +G PG +G  G  G +G  G  G  GPPGP G +G PG  GP+G  G  G +G
Sbjct: 1049 PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQG 1108

Query: 254  MVGAIGATGP---PGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDG 310
             VG  G  GP   PGE+G +G  G  G+KG +G  G  GP G  G +G  G PGI G DG
Sbjct: 1109 PVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1168

Query: 311  TPGTPGMKGSAGQAGQ------PGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSG 364
             PG  G +G  GQ G       PG PG  GL G+PG PG KG  GD G  GP G PG  G
Sbjct: 1169 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRG 1228

Query: 365  PPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQG---PKGEQGPPGIPGPQG 421
            P G  G  GP+G  G  G +G  G++GE G  G PGP G  G   PKGE+G  G  GP G
Sbjct: 1229 PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPG 1288

Query: 422  LPGVKGDKGSPGKTGPRGK---VGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPG 478
              G  G KG PG  GP+G    VG PG  G PGE G  G+ G  G KG+ G  G+PG PG
Sbjct: 1289 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1348

Query: 479  PSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHI--VDVALKMLQEQ 536
            PSG+AG PG  G  GPPG  G  G +G  G  G  G EG       +     A K   E 
Sbjct: 1349 PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEG 1408

Query: 537  LAEVAVSAKREAL-GAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTG 595
            L  +      + L GA G  GPPGP GPPG PG +G  G  G +G PG++G +G  G  G
Sbjct: 1409 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG 1468

Query: 596  PKGKRG---EKGDPGEVGRGH-PGMPGPPGIPGLPGRPG-QAINGKDGDRGSPGAPGEAG 650
             KG RG    +G PG  G G  PG  GP G PG PG PG Q   G  G  G  G  G++G
Sbjct: 1469 EKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSG 1528

Query: 651  RPGLPGPVGLPG 662
             PG PG  G PG
Sbjct: 1529 LPGPPGSPGPPG 1540



 Score =  536 bits (1380), Expect = e-152
 Identities = 326/737 (44%), Positives = 375/737 (50%), Gaps = 118/737 (16%)

Query: 26   RGPPGERGPPGPPGPPGVPGSDGIDGDNGP---PGKAGPPGPKGEPGKAGPDGPDGKPGI 82
            +G  GERGP GPPGPPG  G  G DG+ GP   PG+AGP G  G  G  G  G  G  G+
Sbjct: 612  KGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV 671

Query: 83   DGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP-GFAGPPGPPGPVGLPGEIGI---RGP 138
            DG  G KG  GP G PG  GQ G PGP GLPGP G  GPPG  GP G PG  G+    GP
Sbjct: 672  DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGP 731

Query: 139  KGDPGPDGPS------GPPGPPGKPGRPGT--------IQGLEGSADFLCPTNCPPGMKG 184
             G PG +G S      GPPGP G  G PG         ++GL+GS          PG KG
Sbjct: 732  PGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGF-PGFKG 790

Query: 185  PPGLQGVKGHAGK---RGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAG 241
              GL+G +G  G+   RG  G  G +G+ GP GD G SG+ G  G  G  G+ GYPG  G
Sbjct: 791  DMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG 850

Query: 242  PKGETGPHGYKGMVGAIGA---------------TGPPGEEGPRGPPGRAGEKGDEGS-- 284
            PKG TG  G+ G  G  GA               TGP G  G RGP G+ G KG  G   
Sbjct: 851  PKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDG 910

Query: 285  ----PGIRGPQGITGP---KGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAG 337
                PG RGPQG  GP    G  GPPG  GKDG PG PG +G  G  G+ G PG  G+ G
Sbjct: 911  PPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVG 970

Query: 338  VPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQ----------- 386
              G  G  G  G++G PGP G PG  G PG  G+ G +G+ GPQGI G+           
Sbjct: 971  PQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPG 1030

Query: 387  ----------------KGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKG 430
                            +G QG  GPVG PG +G  G  G  G PG PGPQG PG  G+KG
Sbjct: 1031 ERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKG 1090

Query: 431  SPGKTGPRGKVGDPGV------------AGLPGEKGEKGESGEPGPKGQQGVRGEPGYPG 478
            +PG+ GP+G  G  GV            AG PGE G+KGE GEPG KG +G +GE G PG
Sbjct: 1091 APGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPG 1150

Query: 479  P---SGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQE 535
            P    G  GAPG+ G  G PGPRG  G  G  G  G +G  G          + L+ L  
Sbjct: 1151 PPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG------PIGLQGLPG 1204

Query: 536  QLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTG 595
               E          G  G +GP GPPGPPG  G QGP+G  GP+G PG VG+VG +G  G
Sbjct: 1205 PPGE---------KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKG 1255

Query: 596  PKGKRGEKGDPGEVG-------RGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGA--- 645
              G+ G  G PGE G       RG  G  GPPG  G PG  G    G DG +G+PG    
Sbjct: 1256 EPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPP--GDDGPKGNPGPVGF 1313

Query: 646  PGEAGRPGLPGPVGLPG 662
            PG+ G PG PGP G  G
Sbjct: 1314 PGDPGPPGEPGPAGQDG 1330



 Score =  533 bits (1373), Expect = e-151
 Identities = 323/740 (43%), Positives = 365/740 (49%), Gaps = 83/740 (11%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
            GP GE GP GP G  G  G  G  G  G  GK G PG  G PG+ GP G  G PG  G  
Sbjct: 805  GPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGAN 864

Query: 87   GAKGEPGPMGIPGVKGQPG---------LPGPPGLPGP-GFAGPPGPPGPVGLPGEIGIR 136
            G KG  G  G PG +GQ G           GP G PGP G +G  GPPGP   PGE G +
Sbjct: 865  GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGP---PGERGPQ 921

Query: 137  GPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCP----------------- 179
            GP+G  G  GP GPPGPPGK G PG   G  G   F   T  P                 
Sbjct: 922  GPQGPVGFPGPKGPPGPPGKDGLPGH-PGQRGETGFQGKTGPPGPGGVVGPQGPTGETGP 980

Query: 180  ------PGMKGPPGLQGVKGHAGKRGILGDPGHQG---KPGPKGDVGASGEQGIPGPPGP 230
                  PG  GPPG QG+ G AGK G  GDPG QG   K GP G  G  GE+G+PG  G 
Sbjct: 981  IGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA 1040

Query: 231  QGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPG---- 286
             G++G  G  GP G  G  G +G  G  G  G PG  GP+GPPG AGEKG  G  G    
Sbjct: 1041 PGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGP 1100

Query: 287  -----IRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQ 341
                 ++GP G+ GP G  G PG +G  G  G PG KGS G  G+ G PG  GL G  G 
Sbjct: 1101 AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGA 1160

Query: 342  PGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGP 401
            PG  GG G+ G  G QG+ G  G  G  G PGP G IG QG+ G  G++GE G VG  GP
Sbjct: 1161 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1220

Query: 402  QGRQGPKGEQGPPGIPGPQGLPGVKG------DKGSPGKTGPRGKVGDPGVAGLPGEKGE 455
             G  GP+G QGP G  GPQG PG  G      +KG PG+ G  G  G+ GV G  GE+GE
Sbjct: 1221 PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGE 1280

Query: 456  KGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGV--------- 506
            KGE+G PG  G  G +G PG  GP G+ G  G  G PGPPG  G AG  GV         
Sbjct: 1281 KGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGD 1340

Query: 507  ---PGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGP 563
               PG PG  G  G                + +  E     +  A G  G  GP GP GP
Sbjct: 1341 PGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGP 1400

Query: 564  PGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGE---KGDPGEVG-RGHPGMPGP 619
             G PG +G  G PGP G  G+ GA GQ G  GP G  G    KGDPG  G +GHPG+ G 
Sbjct: 1401 AGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGL 1460

Query: 620  PGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGL------PGPVGLPGFCEPAACLGAS 673
             G PG  G  G    G  G +GSPGA G+ G PG       PGP GLPG   P    G++
Sbjct: 1461 IGPPGEQGEKGD--RGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1518

Query: 674  AYASAR----LTEPGSIKGP 689
              A  +    L  P    GP
Sbjct: 1519 GPAGQKGDSGLPGPPGSPGP 1538



 Score =  531 bits (1369), Expect = e-151
 Identities = 309/681 (45%), Positives = 352/681 (51%), Gaps = 61/681 (8%)

Query: 25   IRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDG------PDG 78
            + G PG  G  GP G  G PG  G +G+ G  G AG PGP+G+ G  GP G      P G
Sbjct: 839  VPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTG 898

Query: 79   KPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGP 138
            KPG  G +G  G PGP   PG +G  G  GP G PGP   GPPGPPG  GLPG  G RG 
Sbjct: 899  KPGPKGTSGGDGPPGP---PGERGPQGPQGPVGFPGP--KGPPGPPGKDGLPGHPGQRGE 953

Query: 139  ---KGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHA 195
               +G  GP GP G  GP G  G  G I G  G           PG  GPPG QG+ G A
Sbjct: 954  TGFQGKTGPPGPGGVVGPQGPTGETGPI-GERGH----------PGPPGPPGEQGLPGAA 1002

Query: 196  GKRGILGDPGHQ---GKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYK 252
            GK G  GDPG Q   GK GP G  G  GE+G+PG  G  G++G  G  GP G  G  G +
Sbjct: 1003 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1062

Query: 253  GMVGAIGATGPPGEEGPRGPPGRAGEK---------GDEGSPGIRGPQGITGPKGATGPP 303
            G  G  G  G PG  GP+GPPG AGEK         G  G  G++GP G+ GP G  G P
Sbjct: 1063 GSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSP 1122

Query: 304  GINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFS 363
            G +G  G  G PG KGS G  G+ G PG  GL G  G PG  GG G+ G  G QG+ G  
Sbjct: 1123 GEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK 1182

Query: 364  GPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLP 423
            G  G  G PGP G IG QG+ G  G++GE G VG  GP G  GP+G QGP G  GPQG P
Sbjct: 1183 GDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPP 1242

Query: 424  GV------KGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYP 477
            G        G+KG PG+ G  G  G+ GV G  GE+GEKGE+G PG  G  G +G PG  
Sbjct: 1243 GSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDD 1302

Query: 478  GPSGDAGAPGVQGYPGPPGPRGLAGNRGV------------PGQPGRQGVEGRDATDQHI 525
            GP G+ G  G  G PGPPG  G AG  GV            PG PG  G  G        
Sbjct: 1303 GPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKR 1362

Query: 526  VDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIV 585
                    + +  E     +  A G  G  GP GP GP G PG +G  G PGP G  G+ 
Sbjct: 1363 GPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLP 1422

Query: 586  GAVGQIGNTGPKGK---RGEKGDPGEVG-RGHPGMPGPPGIPGLPGRPGQAINGKDGDRG 641
            GA GQ G  GP G     G KGDPG  G +GHPG+ G  G PG  G  G    G  G +G
Sbjct: 1423 GAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGD--RGLPGTQG 1480

Query: 642  SPGAPGEAGRPGLPGPVGLPG 662
            SPGA G+ G PG  GP+G PG
Sbjct: 1481 SPGAKGDGGIPGPAGPLGPPG 1501



 Score =  520 bits (1339), Expect = e-147
 Identities = 322/748 (43%), Positives = 372/748 (49%), Gaps = 94/748 (12%)

Query: 25   IRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDG 84
            +RGPPG  G  G PGP G PGS G  G++G PG  GP G +G PG  G  G  G+PG DG
Sbjct: 527  LRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADG 586

Query: 85   LTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP-GFAGPPGPPGPVGLPGEIGIRGPKGDPG 143
              G  GEPG  G  G  G PGLPG  G  G  G  GPPGPPG  G+ GE G  GP+G PG
Sbjct: 587  GRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPG 646

Query: 144  PDGPS---GPPGPPGKPGRPGT--IQGLEGSADFLCPTN--CPPGMKGPPGLQGV----- 191
              GP    GP G PG PG+PG   + G  G    + P     PPG +G PG QG+     
Sbjct: 647  EAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 706

Query: 192  -------KGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYP------- 237
                   KG  GK G+ G PG  G PG  G  G SGE+G  GPPGPQG  GYP       
Sbjct: 707  PIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKG 766

Query: 238  -----GMAGPKGETGPHGY---------KGMVGAIGATGPPGEEGPRGPPGR-------- 275
                 G+ G KGE G  G+         KG  G +G  GP GE+GP GP GR        
Sbjct: 767  ADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 826

Query: 276  ----AGEKGDEGSPGIRGPQGITGPKGATGPPGINGKD------GTPGTPGMKGSAGQAG 325
                AGEKG  G PG+ G  G  GPKG+TG PG  G +      G  G PG +G  G  G
Sbjct: 827  PSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTG 886

Query: 326  QPGSPGHQGLAGVPGQPGTKGG------PGDQGEPGPQGLPGF------SGPPGKE---G 370
              GS G +G  G PG  GT GG      PG++G  GPQG  GF       GPPGK+   G
Sbjct: 887  PRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPG 946

Query: 371  EPGPRGEI---------GPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQG 421
             PG RGE          GP G++G +G  GE GP+G+ G  G  GP GEQG PG  G +G
Sbjct: 947  HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEG 1006

Query: 422  LPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSG 481
              G  G +G  GK GP G  G PG  GLPG +G  G  G  GP+G  G  G PG  G +G
Sbjct: 1007 AKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAG 1066

Query: 482  DAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVA 541
             AG  G+ G PGP GP G AG +G PG+ G QG  GRD     +       L        
Sbjct: 1067 TAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPV------GLPGPAGPAG 1120

Query: 542  VSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRG 601
               +    G +G  G  G  G  G  G  GP G  GP G PGI G  G+ G  G +G  G
Sbjct: 1121 SPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFG 1180

Query: 602  EKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLP 661
            +KGD G   RG PG PGP G+ GLPG PG+   G++GD G  G PG  G  G  GP G  
Sbjct: 1181 QKGDEG--ARGFPGPPGPIGLQGLPGPPGE--KGENGDVGPMGPPGPPGPRGPQGPNGAD 1236

Query: 662  GFCEPAACLGASAYASARLTEPGSIKGP 689
            G   P   +G S        EPG    P
Sbjct: 1237 GPQGPPGSVG-SVGGVGEKGEPGEAGNP 1263



 Score =  507 bits (1305), Expect = e-143
 Identities = 300/693 (43%), Positives = 354/693 (51%), Gaps = 110/693 (15%)

Query: 27   GPPGERGP---------PGPPGPPGVPGSDGIDG------DNGPPGKAGPPGP------- 64
            GPPGERGP         PGP GPPG PG DG+ G      + G  GK GPPGP       
Sbjct: 913  GPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQ 972

Query: 65   -----------KGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGL---PGPP 110
                       +G PG  GP G  G PG  G  GAKG+PGP GI G  G  GL   PG  
Sbjct: 973  GPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGER 1032

Query: 111  GLPGP-------GFAGPPGPPGPVGLPGE---IGIRGPKGDPGPDGPSGPPGPPGKPGRP 160
            GLPG        G  GP GPPGPVG PGE    G  GP G PG  GP GPPGP G+ G P
Sbjct: 1033 GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1092

Query: 161  GTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASG 220
            G  +G +G A          G++GP GL G  G AG  G  GD G  G+PG KG  G  G
Sbjct: 1093 GE-KGPQGPAG-------RDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKG 1144

Query: 221  EQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVG------AIGATGPPGEEGPRGPPG 274
            E G PGPPG QG  G PG+AG  GE GP G +GM G      A G  GPPG  G +G PG
Sbjct: 1145 ENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPG 1204

Query: 275  RAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPG---SPG 331
              GEKG+ G  G  GP G  GP+G  GP G +G  G PG+ G  G  G+ G+PG   +PG
Sbjct: 1205 PPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPG 1264

Query: 332  HQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEG------------EPGPRGEIG 379
              G AGV G  G +G  G+ G PG  G PG  GPPG +G            +PGP GE G
Sbjct: 1265 PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1324

Query: 380  PQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRG 439
            P G  G  GD+GE G  GQPGP G   P GE GPPG PG +G PG  G +G  G+ G +G
Sbjct: 1325 PAGQDGVGGDKGEDGDPGQPGPPG---PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKG 1381

Query: 440  KVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRG 499
            + G  G  G  G  G +G +G+PGP+G +G+      PGP G+ G PG  G  GPPGP G
Sbjct: 1382 EAGAEGPPGKTGPVGPQGPAGKPGPEGLRGI------PGPVGEQGLPGAAGQDGPPGPMG 1435

Query: 500  LAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPG 559
              G  G+ G PG +G +G               L   +       ++   G  G  G PG
Sbjct: 1436 PPGLPGLKGDPGSKGEKGHPG------------LIGLIGPPGEQGEKGDRGLPGTQGSPG 1483

Query: 560  PPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGP 619
              G  G PG  GP G PGP G+PG  G  G  G+TGP G++G+            G+PGP
Sbjct: 1484 AKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDS-----------GLPGP 1532

Query: 620  PGIPGLPG---RPGQAINGKDGDRGSPGAPGEA 649
            PG PG PG   +P   ++ K   R + G   +A
Sbjct: 1533 PGSPGPPGEVIQPLPILSSKKTRRHTEGMQADA 1565



 Score =  500 bits (1287), Expect = e-141
 Identities = 305/722 (42%), Positives = 360/722 (49%), Gaps = 98/722 (13%)

Query: 33   GPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEP 92
            GPPGP GP G+ G         PPG  GP GP G+PG  GP G  G PG DGL    G P
Sbjct: 442  GPPGPAGPAGIMG---------PPGLQGPTGPPGDPGDRGPPGRPGLPGADGLP---GPP 489

Query: 93   GPM-GIPGVKGQPGLPGPPGLPGPGFA------------GPPGP------PGPVGLPGEI 133
            G M  +P   G  G  GP        A            GPPGP      PGPVG PG  
Sbjct: 490  GTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSS 549

Query: 134  GIRGPKGDPGPDGP---SGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQG 190
            G +G  GDPGP GP    GPPGP GKPG+ G   G +G            GM G PG +G
Sbjct: 550  GAKGESGDPGPQGPRGVQGPPGPTGKPGKRGR-PGADGGR----------GMPGEPGAKG 598

Query: 191  VKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPH- 249
             +G  G  G+ GD GH+G+ GP+G  G  G+ G+ G  G  G RG PG AGP+G  GP  
Sbjct: 599  DRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRG 658

Query: 250  -----GYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGP-- 302
                 G  GM G  G  GP G  GP+G PG  G++G+ G  G+ GPQG  GP G  GP  
Sbjct: 659  TPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQG 718

Query: 303  ----PGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGG------PGDQG 352
                 G+ G DG PG PG +G +G+ G  G PG QG  G PG  G KG        G +G
Sbjct: 719  KPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKG 778

Query: 353  EPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQG 412
            E G  G PGF G  G +G+ G  G+IGP+G  G +G +G  GP G PGP G+ G KG+ G
Sbjct: 779  EKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLG 838

Query: 413  PPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGE------------KGESG 460
             PG+PG  G  G KG  G PG  G  G+ G  GVAG PG +G+            +G +G
Sbjct: 839  VPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTG 898

Query: 461  EPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDA 520
            +PGPKG  G  G PG PG  G  G  G  G+PGP GP G  G  G+PG PG++G  G   
Sbjct: 899  KPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 958

Query: 521  TDQHIVDVALKMLQEQLAEVAVSAKR-----------EAL-GAVGMMGPPGPPGPPGYPG 568
                     +   Q    E     +R           + L GA G  G  G PGP G  G
Sbjct: 959  KTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISG 1018

Query: 569  KQGP---HGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGL 625
            K GP    G PG RG+PG  GA G  G  GP+G  G  G PGE  RG  G  GP G+PG 
Sbjct: 1019 KDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGE--RGSAGTAGPIGLPGR 1076

Query: 626  PGRPGQAINGKDGDRGSP---GAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASARLTE 682
            PG  G    G  G++G+P   G  G AGR G+ GPVGLPG   PA   G        + E
Sbjct: 1077 PGPQGPP--GPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG-DKGEIGE 1133

Query: 683  PG 684
            PG
Sbjct: 1134 PG 1135



 Score =  313 bits (802), Expect = 3e-85
 Identities = 177/388 (45%), Positives = 206/388 (53%), Gaps = 52/388 (13%)

Query: 20   LALAQIRGPPGER---------GPPGPPGPPGVPGSDGIDGDNGPPGKAGP---PGPKGE 67
            + L  + GPPGE+         GPPGPPGP G  G +G DG  GPPG  G     G KGE
Sbjct: 1197 IGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1256

Query: 68   PGKAGPDGPDGKPGIDGLTGAKGE------PGPMGIPGVKGQPGLPGPPGLPGP-GFAGP 120
            PG+AG  GP G+ G+ G  G +GE      PG  G PG KG PG  GP G PGP GF G 
Sbjct: 1257 PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD 1316

Query: 121  PGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPP 180
            PGPPG  G  G+ G+ G KG+ G  G  GPPGP G+ G PG                 PP
Sbjct: 1317 PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG-----------------PP 1359

Query: 181  GMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMA 240
            G +GPPG  G +G  G++G  G+ G +G PG  G V   G QG  G PGP+G+RG P   
Sbjct: 1360 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPV---GPQGPAGKPGPEGLRGIP--- 1413

Query: 241  GPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGAT 300
                  GP G +G+ GA G  GPP   GP GPPG  G KGD GS G +G  G+ G  G  
Sbjct: 1414 ------GPVGEQGLPGAAGQDGPP---GPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPP 1464

Query: 301  GPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLP 360
            G  G  G  G PGT G  G+ G  G PG  G  G  G PG PG +G  G++G  GP G  
Sbjct: 1465 GEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQK 1524

Query: 361  GFSGPPGKEGEPGPRGE-IGPQGIMGQK 387
            G SG PG  G PGP GE I P  I+  K
Sbjct: 1525 GDSGLPGPPGSPGPPGEVIQPLPILSSK 1552


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score =  537 bits (1383), Expect = e-152
 Identities = 313/692 (45%), Positives = 360/692 (52%), Gaps = 59/692 (8%)

Query: 27   GPPGERGPPGPPGP---PGVPGSDGIDGDNGPPGKAGPPG---PKGEPGKAGPDGP---D 77
            G PG  GPPGP GP   PG PG+ G  G+ GP G  GP G   P+GEPG  G  GP    
Sbjct: 348  GQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGAS 407

Query: 78   GKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP-GFAGPPGPPGPVGLPGEIGIR 136
            G PG DG+ GAKG  G    PG+ G PG PGP G PGP G  GP GP G  G PG  G +
Sbjct: 408  GNPGTDGIPGAKGSAGA---PGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFK 464

Query: 137  G---PKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKG 193
            G   PKG+PGP GP G PGP G+ G+    +G  G    + P   PPG +G PG +G  G
Sbjct: 465  GEQGPKGEPGPAGPQGAPGPAGEEGK----RGARGEPGGVGPIG-PPGERGAPGNRGFPG 519

Query: 194  H---AGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHG 250
                AG +G  G+ G  G  GPKG  G  G  G PG PG +G+ G PG AGP+G+ GP G
Sbjct: 520  QDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSG 579

Query: 251  YKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDG 310
              G  G  G  GP G  G  G  G  G KG  G PG  G +G+ G  G  G PG +G+ G
Sbjct: 580  APGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETG 639

Query: 311  TPGTPGMKGSAGQAGQPGSPG---HQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGP-- 365
              G PG  G AG+ G+ G+PG    QGL G PG PG  G PGDQG PG  G PG  GP  
Sbjct: 640  AAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRG 699

Query: 366  ----PGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQG 421
                PG+ G PG +G  GP+G+ G  G  G +G  G  GP G QGP G QG PG  G  G
Sbjct: 700  ERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAG 759

Query: 422  LPGVKGDKG---------SPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRG 472
            + G KGD+G         +PGK G RG  G  G  G  G  GEKGE G PGP G  G RG
Sbjct: 760  IAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARG 819

Query: 473  EPGY------PGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIV 526
             PG       PGP+G AG PG  G PG  G +G AG +G  G PG QG  G         
Sbjct: 820  APGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTG 879

Query: 527  DVALKMLQEQLAEVAVSAKREALGAVGMMGP---PGPPGPPGYPGKQGPHGHPGPRGVPG 583
                K  +        +    A G VG  G    PGPPGPPG  GK GP G  G  G PG
Sbjct: 880  VTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPG 939

Query: 584  IVGAVGQIGNTGPKGKRGEKGDPGEVGRGHP----GMPGPPGIPGLPGRPGQ----AING 635
              G  G  G  GP G++GE GD G  G   P    G+ G  GI GLPG+ G+     + G
Sbjct: 940  RAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPG 999

Query: 636  KDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPA 667
              G+ G  GAPG +G  G PGPVG PG   PA
Sbjct: 1000 PSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA 1031



 Score =  530 bits (1365), Expect = e-150
 Identities = 317/693 (45%), Positives = 367/693 (52%), Gaps = 79/693 (11%)

Query: 22   LAQIRGPPGERGPPGPPGP------PGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDG 75
            LA  +G PGERGP G  GP      PG PG  G+ G  G  G+ G  GP+G+ G +G  G
Sbjct: 523  LAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPG 582

Query: 76   PDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGI 135
             DG+PG  G  GA+G+PG MG PG KG  G PG  G  G      PG PG  GLPG+ G 
Sbjct: 583  EDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGL-----PGAPGLRGLPGKDGE 637

Query: 136  RGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHA 195
             G  G PGP GP+G  G  G PG P   QGL G          PPG  G PG QGV G A
Sbjct: 638  TGAAGPPGPAGPAGERGEQGAPG-PSGFQGLPGPPG-------PPGEGGKPGDQGVPGEA 689

Query: 196  GKRGILGDPGHQGKPGPKGDVGASGEQG---IPGPPGPQGIRGYPGMAGPKGETGPHGYK 252
            G  G++G  G +G PG +G  GA G QG   +PG PG  G +G  G AGP G  GP G +
Sbjct: 690  GAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQ 749

Query: 253  GMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTP 312
            GM G  GA G  G   P+G  G  GEKG EG+PG  G +G+TGP G  GP G NG+ G  
Sbjct: 750  GMPGERGAAGIAG---PKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEV 806

Query: 313  GTPGMKGSAGQAGQPGS------PGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPP 366
            G PG  GSAG  G PG       PG  G AG PG  G  G  G+QGE G +G  G  GP 
Sbjct: 807  GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 866

Query: 367  GKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVK 426
            G  G PGP+G  G  G  G +G QG  G  G PG  GR GP G  G PG PGP G  G  
Sbjct: 867  GPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKD 926

Query: 427  GDKGSPGKTGPRGKVGDPGV---AGLPGEKGEKGE------SGEPGPK------------ 465
            G KG+ G +GP G+ G+PG+   AG PGEKGE G+       G PGP+            
Sbjct: 927  GPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLP 986

Query: 466  GQQGVRGEPGYPGPSGD---AGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATD 522
            GQ+G RG PG PGPSG+    GAPG  G  GPPGP G  G  G  G+PGR+G  G D   
Sbjct: 987  GQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPP 1046

Query: 523  QHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGH---PGPR 579
                   +K             +  A+GA G  GPPG PGP G  GKQG  G     GP 
Sbjct: 1047 GRDGAAGVK---------GDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPM 1097

Query: 580  GVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-RGH------PGMPGPPGIPGLPGRPGQA 632
            G  G  GA G  G  GP+G +GE G+PGE G +GH       G+PGPPG  G  G  G A
Sbjct: 1098 GPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPA 1157

Query: 633  INGKDGDRGSPGAPGEAGRP---GLPGPVGLPG 662
              G  G RG PG  G +G+    G+PGP+G PG
Sbjct: 1158 --GPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1188



 Score =  521 bits (1343), Expect = e-148
 Identities = 327/763 (42%), Positives = 367/763 (48%), Gaps = 126/763 (16%)

Query: 22  LAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGK---AGPPGPKGEPGKAGPDGPDG 78
           L  ++GP G  GP GPPGP G PG  G  G+ G PG+   +GP GP+G PG  G  G DG
Sbjct: 196 LGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDG 255

Query: 79  KPGIDGLTGAKGEPGPMGIPGVKGQPGLPGP------PGLPG----------------PG 116
           + G  G  G +G PGP G  G  G PGLPG       PGL G                PG
Sbjct: 256 EAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPG 315

Query: 117 FAGPPGPPGPVGLPGE---------IGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLE 167
             G PGP GP GLPGE          G RG  G PGP GP GP GP G PG PG   G +
Sbjct: 316 ENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGA-PGAK 374

Query: 168 GSADFLCPTNC--PPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIP 225
           G A    PT    P G +GP G  G  G  G  G  G+PG  G PG KG  GA G  G P
Sbjct: 375 GEAG---PTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAP 431

Query: 226 ------GPPGPQGI---------RGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEE--- 267
                 GPPGPQG           G PG+AG KGE GP G  G  G  GA GP GEE   
Sbjct: 432 GFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKR 491

Query: 268 ---------GPRGPPGRAGEKGDEGSP---GIRGPQGI---TGPKGATGPPGINGKDGTP 312
                    GP GPPG  G  G+ G P   G+ GP+G     GP G  GP G NG  G P
Sbjct: 492 GARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRP 551

Query: 313 GTPGMKGSAGQAGQPGSPGHQGL---AGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKE 369
           G PG+ G+ G  G+PG  G QG    +G PG+ G  G PG QG  G  G+ GF GP G  
Sbjct: 552 GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 611

Query: 370 GEPGPRGE---IGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGL---P 423
           GEPG  GE    G  G+ G  G  GE G  G PGP G  G +GEQG PG  G QGL   P
Sbjct: 612 GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP 671

Query: 424 GVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYP------ 477
           G  G+ G PG  G  G+ G PG+ G  GE+G  GE G PG +G QG RG PG P      
Sbjct: 672 GPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPK 731

Query: 478 GPSGDAGAPGVQGYP---------------GPPGPRGLAGNRGVPGQPGRQGVEGRDATD 522
           G SG AG PG QG P               GP G RG  G +G  G PG+ G  G     
Sbjct: 732 GASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPI 791

Query: 523 QHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGY---------------- 566
                      + ++     +    A GA G  G  GPPGP G+                
Sbjct: 792 GPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQ 851

Query: 567 --PGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-RGHPGMPGPPGIP 623
              G++G  G PGP+G  G  G  G  G TGPKG RG +G PG  G  G  G  GPPG  
Sbjct: 852 GEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSN 911

Query: 624 GLPGRPG-QAINGKDGD---RGSPGAPGEAGRPGLPGPVGLPG 662
           G PG PG    +GKDG    RG  G PG AG PGL GP G PG
Sbjct: 912 GNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPG 954



 Score =  518 bits (1335), Expect = e-147
 Identities = 310/717 (43%), Positives = 357/717 (49%), Gaps = 106/717 (14%)

Query: 33  GPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEP 92
           G PGP G  G PG   I    GP G  GP GP GE G  G  G  G+ G  G  G  GEP
Sbjct: 98  GQPGPKGQKGEPGD--IKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 155

Query: 93  GPMGIPGVKGQPGLPGPPGLPG-------------------------PGFAGPPGPPGPV 127
           G  G PG  G PG PGPPGL G                          G  GP GPPGP 
Sbjct: 156 GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 215

Query: 128 GLPGEIGIRGPKGDP------GPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPG 181
           G PG  G +G  G+P      GP GP GPPGPPGKPG  G   G  G A          G
Sbjct: 216 GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGE-AGKPGKA----------G 264

Query: 182 MKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAG 241
            +GPPG QG +G  G  G+ G  GH+G PG  G  G +G  G+ G  G  G  G PG  G
Sbjct: 265 ERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMG 324

Query: 242 PKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATG 301
           P+G  G  G  G  GA GA G  G+ GP GPPG  G  G  G PG  G +G  GP GA G
Sbjct: 325 PRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARG 384

Query: 302 PPGINGKDGTPGTPGMKGSAGQAGQPGS---PGHQGLAGVPGQPGTKGGPGDQGEPGPQG 358
           P G  G  G PGTPG  G AG +G PG+   PG +G AG PG  G  G PG +G PGPQG
Sbjct: 385 PEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQG 444

Query: 359 LPGFSGPPGKEGEP---------GPRGE---IGPQGIMGQKGDQGERGPVGQPGPQGRQG 406
             G  GP G+ GEP         GP+GE    GPQG  G  G++G+RG  G+PG  G  G
Sbjct: 445 ATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIG 504

Query: 407 PKGEQGPP---GIPGPQGLPGVK---GDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESG 460
           P GE+G P   G PG  GL G K   G++G  G  GP+G  GDPG  G PG  G +G +G
Sbjct: 505 PPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTG 564

Query: 461 EP---------GPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPR---GLAGNRGVPG 508
            P         GP G  G  G PG PGP G  G PGV G+PGP G     G AG +G+PG
Sbjct: 565 RPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPG 624

Query: 509 QPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPG 568
            PG +G+ G+D       +                 ++ A G  G  G PGPPGPPG  G
Sbjct: 625 APGLRGLPGKDG------ETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGG 678

Query: 569 KQGPHGHPGPRGVPGIVGA------VGQIGNTGPKGKRGEKGDPGEVG----------RG 612
           K G  G PG  G PG+VG        G+ G+ G +G +G +G PG  G           G
Sbjct: 679 KPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAG 738

Query: 613 HPGMPGPPGIPGLPGRPGQA-INGKDGDRGS------PGAPGEAGRPGLPGPVGLPG 662
            PG  GPPG+ G+PG  G A I G  GDRG        GAPG+ G  GL GP+G PG
Sbjct: 739 PPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPG 795



 Score =  504 bits (1298), Expect = e-142
 Identities = 293/647 (45%), Positives = 332/647 (51%), Gaps = 51/647 (7%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
            G PGE G PGPPGP G  G  G+ G  GP G  G PG  GE G  G  G  G PG DG T
Sbjct: 579  GAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGET 638

Query: 87   GAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDG 146
            GA G PGP G  G +G+ G PGP G  G    GPPGPPG  G PG+ G+ G  G PG  G
Sbjct: 639  GAAGPPGPAGPAGERGEQGAPGPSGFQG--LPGPPGPPGEGGKPGDQGVPGEAGAPGLVG 696

Query: 147  PSGPPGPPGKPGRPGTI-----QGLEGSADFLCPTNC-----PPGMKGPPGLQGVKGHAG 196
            P G  G PG+ G PG       +GL G+     P        PPG +GPPGLQG+ G  G
Sbjct: 697  PRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERG 756

Query: 197  KRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVG 256
              GI G  G +G  G KG  GA G+ G  G  GP G  G  G  G KGE GP G  G  G
Sbjct: 757  AAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAG 816

Query: 257  AIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPG--- 313
            A GA G  GE GP GP G AG  G +G PG +G QG  G KG  G PG  G  G PG   
Sbjct: 817  ARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQG 876

Query: 314  ---TPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGP------QGLPGFSG 364
                 G KG+ G  G PG+ G  G AG  G PG+ G PG  G PGP      +G  G SG
Sbjct: 877  PTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSG 936

Query: 365  PPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKG---------EQGPPG 415
            PPG+ GEPG +G  GP G  G+ GD G  G  G PGPQG  G +G         E+G PG
Sbjct: 937  PPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG 996

Query: 416  IPGPQGLPGVKGDKGSPGKTGPRGKVGDPGV---AGLPGEKGEKGESGEPGPKGQQGVRG 472
            +PGP G PG +G  G+ G  GP G VG PG+   AG PG +G  G  G PG  G  GV+G
Sbjct: 997  LPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG 1056

Query: 473  EPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKM 532
            + G  G  G  GAPG  G PGP GP G  G+RG  G  G  G  G             + 
Sbjct: 1057 DRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1116

Query: 533  LQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQ-- 590
             + +  E      +   G  G+ G PGPPGP G  G  GP G  GPRG PG VG  G+  
Sbjct: 1117 DKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDG 1176

Query: 591  -------IGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPG 630
                   IG  GP+G+ GE G  G      PG PGPPG PG PG PG
Sbjct: 1177 ANGIPGPIGPPGPRGRSGETGPAGP-----PGNPGPPGPPGPPG-PG 1217



 Score =  415 bits (1066), Expect = e-116
 Identities = 247/576 (42%), Positives = 279/576 (48%), Gaps = 92/576 (15%)

Query: 26   RGPPGERGPPGPPG---PPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGI 82
            RG PGERG PG  G   P G+PG+ G DG  G  G AGPPG +G PG  G  G  G  GI
Sbjct: 701  RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 760

Query: 83   DGLTGAKG---EPGPMGIPGVKGQPGLPGPPGLPGP----GFAGPPGPPGPVGLPGEIGI 135
             G  G +G   E GP G PG  G  GL GP G PGP    G  G  GPPGP G  G  G 
Sbjct: 761  AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA 820

Query: 136  RGPKGDPGPDGPSGPPGPPGKPGRPGTI-----QGLEGSADFLCPTNCPPGMKGPPGLQG 190
             G +G+ GP GP+G  GPPG  G+PG        G +G A    P   P G  GP G  G
Sbjct: 821  PGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQG-PSGAPGPQGPTG 879

Query: 191  VKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHG 250
            V G  G RG  G PG  G PG  G VG  G  G PGPPGP G  G  G  G +G++GP G
Sbjct: 880  VTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPG 939

Query: 251  YKGMVGAIGATGPPGE------------EGPRGPPGRAGEKGDEGSPGIRGPQGI----- 293
              G  G  G  GPPGE            EGP GP G AG++G  G PG RG +G      
Sbjct: 940  RAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPG 999

Query: 294  -TGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQG 352
             +G  G  G PG +G  G PG  G  G  G AG+PG  G  G  G PG+ G  G  GD+G
Sbjct: 1000 PSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRG 1059

Query: 353  EPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQG 412
            E G  G PG  GPPG  G  GP G+ G +G  G +G  G  GP G  G QG QGP+G+  
Sbjct: 1060 ETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGD-- 1117

Query: 413  PPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRG 472
                         KG+ G PG+ G +G  G  G+ GLPG  G  G+ G  GP G  G RG
Sbjct: 1118 -------------KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRG 1164

Query: 473  EPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKM 532
             PG  GPSG  GA G+ G  GPPGPRG +G  G  G PG                     
Sbjct: 1165 PPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNP------------------- 1205

Query: 533  LQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPG 568
                                   GPPGPPGPPG PG
Sbjct: 1206 -----------------------GPPGPPGPPG-PG 1217



 Score =  313 bits (802), Expect = 3e-85
 Identities = 189/457 (41%), Positives = 221/457 (48%), Gaps = 60/457 (13%)

Query: 260 ATGPPGEEGPRGPP-------GRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTP 312
           A+G PG +G +G P       G  G  G +G  G +GP+G  G KG  G PG  G+DG P
Sbjct: 96  ASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 155

Query: 313 GTPGMKGSAGQAGQPGSPGHQG---------------------LAGVPGQPGTKGGPGDQ 351
           GTPG  G  G  G PG PG  G                     + G  G  G +G PG  
Sbjct: 156 GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 215

Query: 352 GEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQ 411
           G PGPQ   GF G PG+ GEPG  G +GP+G  G  G  G+ G  G+PG  G +GP G Q
Sbjct: 216 GAPGPQ---GFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 272

Query: 412 GPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVR 471
           G  G PG  GLPGVKG +G PG  G +G+ G PGV    GE G  GE+G PGP G +G+ 
Sbjct: 273 GARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGV---KGESGSPGENGSPGPMGPRGLP 329

Query: 472 GEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALK 531
           GE G  GP+G AGA G  G PGP GP G  G  G PG PG  G +G             +
Sbjct: 330 GERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQ 389

Query: 532 MLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQI 591
             + +           A G  G  G PG  G  G PG  G  G PGPRG PG  GA G +
Sbjct: 390 GPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPL 449

Query: 592 GNTGP---------KGKRGEKGDPGEVG----------------RGHPGMPGPPGIPGLP 626
           G  G          KG++G KG+PG  G                RG PG  GP G PG  
Sbjct: 450 GPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGER 509

Query: 627 GRPG-QAINGKDGDRGSPGAPGEAGRPGLPGPVGLPG 662
           G PG +   G+DG  G  GAPGE G  GL GP G  G
Sbjct: 510 GAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANG 546



 Score =  231 bits (590), Expect = 1e-60
 Identities = 138/354 (38%), Positives = 163/354 (46%), Gaps = 49/354 (13%)

Query: 356 PQGLPGFSGPPGKEGEPGPRGEI-------------GPQGIMGQKGDQGERGPVGQPGPQ 402
           P  L   SG PG +G+ G  G+I             GP G  G +GD+G++G  G PGP+
Sbjct: 90  PTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPR 149

Query: 403 GRQGPKGEQGPPGIPGPQGLPG---------------------------VKGDKGSPGKT 435
           GR G  G  G PG PGP G PG                           ++G  G  G  
Sbjct: 150 GRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPR 209

Query: 436 GPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPP 495
           GP G  G PG  G  G  GE GE G  GP G +G  G PG PG  G+AG PG  G  GPP
Sbjct: 210 GPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPP 269

Query: 496 GPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMM 555
           GP+G  G  G PG PG +G  G    D    +     ++ +      +     +G  G+ 
Sbjct: 270 GPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLP 329

Query: 556 GPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG----- 610
           G  G  GP G  G +G  G PGP G PG VG  G  G  G  G +GE G  G  G     
Sbjct: 330 GERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQ 389

Query: 611 --RGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPG 662
             RG PG PG PG  G  G PG   +G  G +GS GAPG AG PG PGP G PG
Sbjct: 390 GPRGEPGTPGSPGPAGASGNPG--TDGIPGAKGSAGAPGIAGAPGFPGPRGPPG 441



 Score =  212 bits (539), Expect = 1e-54
 Identities = 122/271 (45%), Positives = 134/271 (49%), Gaps = 40/271 (14%)

Query: 19   VLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPG---PKGEPGKAGPDG 75
            ++ L   RG  G  G PGP G PG  G+ G  GD GPPG  GPPG   P GEPG+ G  G
Sbjct: 982  IVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPG 1041

Query: 76   PDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGI 135
             DG PG DG  G KG+ G  G  G    PG PGPPG PGP      GP G  G  GE G 
Sbjct: 1042 ADGPPGRDGAAGVKGDRGETGAVGA---PGAPGPPGSPGPA-----GPTGKQGDRGEAGA 1093

Query: 136  RGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHA 195
            +GP G  GP G  G  GP G  G                      G  G PG +G+KGH 
Sbjct: 1094 QGPMGPSGPAGARGIQGPQGPRG--------------------DKGEAGEPGERGLKGHR 1133

Query: 196  GKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMV 255
            G  G+ G P   G PGP GD GAS      GP GP G RG PG  GP G+ G +G  G +
Sbjct: 1134 GFTGLQGLP---GPPGPSGDQGAS------GPAGPSGPRGPPGPVGPSGKDGANGIPGPI 1184

Query: 256  GAIGATGPPGEEGPRGPPGRAGEKGDEGSPG 286
            G  G  G  GE GP GPPG  G  G  G PG
Sbjct: 1185 GPPGPRGRSGETGPAGPPGNPGPPGPPGPPG 1215



 Score =  178 bits (451), Expect = 2e-44
 Identities = 108/281 (38%), Positives = 133/281 (47%), Gaps = 40/281 (14%)

Query: 413 PPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRG 472
           P  +    G PG KG KG PG            + G  G  G +G +GE GP+G +G +G
Sbjct: 90  PTDLATASGQPGPKGQKGEPGDI--------KDIVGPKGPPGPQGPAGEQGPRGDRGDKG 141

Query: 473 EPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKM 532
           E G PGP G  G PG  G PGPPGP    G  G PG  G    +     D+      L +
Sbjct: 142 EKGAPGPRGRDGEPGTPGNPGPPGP---PGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV 198

Query: 533 LQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIG 592
           +Q               G +G MGP GPPGP G PG QG  G+PG  G PG+ G +G  G
Sbjct: 199 MQ---------------GPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRG 243

Query: 593 NTGPKGKRGEKGDPGEVG----RGHPGMPGPPGIPGLPGRPG-------QAINGKDGDRG 641
             GP GK G+ G+ G+ G    RG PG  G  G PG PG PG         ++G  G+ G
Sbjct: 244 PPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAG 303

Query: 642 SPGAPGEAGRP---GLPGPVGLPGFCEPAACLGASAYASAR 679
           +PG  GE+G P   G PGP+G  G        G +  A AR
Sbjct: 304 APGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGAR 344


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score =  537 bits (1383), Expect = e-152
 Identities = 313/692 (45%), Positives = 360/692 (52%), Gaps = 59/692 (8%)

Query: 27  GPPGERGPPGPPGP---PGVPGSDGIDGDNGPPGKAGPPG---PKGEPGKAGPDGP---D 77
           G PG  GPPGP GP   PG PG+ G  G+ GP G  GP G   P+GEPG  G  GP    
Sbjct: 279 GQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGAS 338

Query: 78  GKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP-GFAGPPGPPGPVGLPGEIGIR 136
           G PG DG+ GAKG  G    PG+ G PG PGP G PGP G  GP GP G  G PG  G +
Sbjct: 339 GNPGTDGIPGAKGSAGA---PGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFK 395

Query: 137 G---PKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKG 193
           G   PKG+PGP GP G PGP G+ G+    +G  G    + P   PPG +G PG +G  G
Sbjct: 396 GEQGPKGEPGPAGPQGAPGPAGEEGK----RGARGEPGGVGPIG-PPGERGAPGNRGFPG 450

Query: 194 H---AGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHG 250
               AG +G  G+ G  G  GPKG  G  G  G PG PG +G+ G PG AGP+G+ GP G
Sbjct: 451 QDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSG 510

Query: 251 YKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDG 310
             G  G  G  GP G  G  G  G  G KG  G PG  G +G+ G  G  G PG +G+ G
Sbjct: 511 APGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETG 570

Query: 311 TPGTPGMKGSAGQAGQPGSPG---HQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGP-- 365
             G PG  G AG+ G+ G+PG    QGL G PG PG  G PGDQG PG  G PG  GP  
Sbjct: 571 AAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRG 630

Query: 366 ----PGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQG 421
               PG+ G PG +G  GP+G+ G  G  G +G  G  GP G QGP G QG PG  G  G
Sbjct: 631 ERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAG 690

Query: 422 LPGVKGDKG---------SPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRG 472
           + G KGD+G         +PGK G RG  G  G  G  G  GEKGE G PGP G  G RG
Sbjct: 691 IAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARG 750

Query: 473 EPGY------PGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIV 526
            PG       PGP+G AG PG  G PG  G +G AG +G  G PG QG  G         
Sbjct: 751 APGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTG 810

Query: 527 DVALKMLQEQLAEVAVSAKREALGAVGMMGP---PGPPGPPGYPGKQGPHGHPGPRGVPG 583
               K  +        +    A G VG  G    PGPPGPPG  GK GP G  G  G PG
Sbjct: 811 VTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPG 870

Query: 584 IVGAVGQIGNTGPKGKRGEKGDPGEVGRGHP----GMPGPPGIPGLPGRPGQ----AING 635
             G  G  G  GP G++GE GD G  G   P    G+ G  GI GLPG+ G+     + G
Sbjct: 871 RAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPG 930

Query: 636 KDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPA 667
             G+ G  GAPG +G  G PGPVG PG   PA
Sbjct: 931 PSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA 962



 Score =  530 bits (1365), Expect = e-150
 Identities = 317/693 (45%), Positives = 367/693 (52%), Gaps = 79/693 (11%)

Query: 22   LAQIRGPPGERGPPGPPGP------PGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDG 75
            LA  +G PGERGP G  GP      PG PG  G+ G  G  G+ G  GP+G+ G +G  G
Sbjct: 454  LAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPG 513

Query: 76   PDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGI 135
             DG+PG  G  GA+G+PG MG PG KG  G PG  G  G      PG PG  GLPG+ G 
Sbjct: 514  EDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGL-----PGAPGLRGLPGKDGE 568

Query: 136  RGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHA 195
             G  G PGP GP+G  G  G PG P   QGL G          PPG  G PG QGV G A
Sbjct: 569  TGAAGPPGPAGPAGERGEQGAPG-PSGFQGLPGPPG-------PPGEGGKPGDQGVPGEA 620

Query: 196  GKRGILGDPGHQGKPGPKGDVGASGEQG---IPGPPGPQGIRGYPGMAGPKGETGPHGYK 252
            G  G++G  G +G PG +G  GA G QG   +PG PG  G +G  G AGP G  GP G +
Sbjct: 621  GAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQ 680

Query: 253  GMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTP 312
            GM G  GA G  G   P+G  G  GEKG EG+PG  G +G+TGP G  GP G NG+ G  
Sbjct: 681  GMPGERGAAGIAG---PKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEV 737

Query: 313  GTPGMKGSAGQAGQPGS------PGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPP 366
            G PG  GSAG  G PG       PG  G AG PG  G  G  G+QGE G +G  G  GP 
Sbjct: 738  GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 797

Query: 367  GKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVK 426
            G  G PGP+G  G  G  G +G QG  G  G PG  GR GP G  G PG PGP G  G  
Sbjct: 798  GPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKD 857

Query: 427  GDKGSPGKTGPRGKVGDPGV---AGLPGEKGEKGE------SGEPGPK------------ 465
            G KG+ G +GP G+ G+PG+   AG PGEKGE G+       G PGP+            
Sbjct: 858  GPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLP 917

Query: 466  GQQGVRGEPGYPGPSGD---AGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATD 522
            GQ+G RG PG PGPSG+    GAPG  G  GPPGP G  G  G  G+PGR+G  G D   
Sbjct: 918  GQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPP 977

Query: 523  QHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGH---PGPR 579
                   +K             +  A+GA G  GPPG PGP G  GKQG  G     GP 
Sbjct: 978  GRDGAAGVK---------GDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPM 1028

Query: 580  GVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-RGH------PGMPGPPGIPGLPGRPGQA 632
            G  G  GA G  G  GP+G +GE G+PGE G +GH       G+PGPPG  G  G  G A
Sbjct: 1029 GPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPA 1088

Query: 633  INGKDGDRGSPGAPGEAGRP---GLPGPVGLPG 662
              G  G RG PG  G +G+    G+PGP+G PG
Sbjct: 1089 --GPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1119



 Score =  522 bits (1344), Expect = e-148
 Identities = 316/738 (42%), Positives = 369/738 (50%), Gaps = 108/738 (14%)

Query: 12  LVLLQVVVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKA 71
           LVLL ++V A+ + +G    +  PGP G  G PG   I    GP G  GP GP GE G  
Sbjct: 10  LVLLTLLVAAVLRCQGQDVRQ--PGPKGQKGEPGD--IKDIVGPKGPPGPQGPAGEQGPR 65

Query: 72  GPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPG----------------- 114
           G  G  G+ G  G  G  GEPG  G PG  G PG PGPPGL G                 
Sbjct: 66  GDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGA 125

Query: 115 --------PGFAGPPGPPGPVGLPGEIGIRGPKGDP------GPDGPSGPPGPPGKPGRP 160
                    G  GP GPPGP G PG  G +G  G+P      GP GP GPPGPPGKPG  
Sbjct: 126 QLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDD 185

Query: 161 GTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASG 220
           G   G  G A          G +GPPG QG +G  G  G+ G  GH+G PG  G  G +G
Sbjct: 186 GE-AGKPGKA----------GERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAG 234

Query: 221 EQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKG 280
             G+ G  G  G  G PG  GP+G  G  G  G  GA GA G  G+ GP GPPG  G  G
Sbjct: 235 APGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAG 294

Query: 281 DEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGS---PGHQGLAG 337
             G PG  G +G  GP GA GP G  G  G PGTPG  G AG +G PG+   PG +G AG
Sbjct: 295 GPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAG 354

Query: 338 VPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEP---------GPRGE---IGPQGIMG 385
            PG  G  G PG +G PGPQG  G  GP G+ GEP         GP+GE    GPQG  G
Sbjct: 355 APGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPG 414

Query: 386 QKGDQGERGPVGQPGPQGRQGPKGEQGPP---GIPGPQGLPGVK---GDKGSPGKTGPRG 439
             G++G+RG  G+PG  G  GP GE+G P   G PG  GL G K   G++G  G  GP+G
Sbjct: 415 PAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKG 474

Query: 440 KVGDPGVAGLPGEKGEKGESGEP---------GPKGQQGVRGEPGYPGPSGDAGAPGVQG 490
             GDPG  G PG  G +G +G P         GP G  G  G PG PGP G  G PGV G
Sbjct: 475 ANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMG 534

Query: 491 YPGPPGPR---GLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKRE 547
           +PGP G     G AG +G+PG PG +G+ G+D       +                 ++ 
Sbjct: 535 FPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDG------ETGAAGPPGPAGPAGERGEQG 588

Query: 548 ALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGA------VGQIGNTGPKGKRG 601
           A G  G  G PGPPGPPG  GK G  G PG  G PG+VG        G+ G+ G +G +G
Sbjct: 589 APGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQG 648

Query: 602 EKGDPGEVG----------RGHPGMPGPPGIPGLPGRPGQA-INGKDGDRGS------PG 644
            +G PG  G           G PG  GPPG+ G+PG  G A I G  GDRG        G
Sbjct: 649 PRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEG 708

Query: 645 APGEAGRPGLPGPVGLPG 662
           APG+ G  GL GP+G PG
Sbjct: 709 APGKDGGRGLTGPIGPPG 726



 Score =  521 bits (1343), Expect = e-148
 Identities = 327/763 (42%), Positives = 367/763 (48%), Gaps = 126/763 (16%)

Query: 22  LAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGK---AGPPGPKGEPGKAGPDGPDG 78
           L  ++GP G  GP GPPGP G PG  G  G+ G PG+   +GP GP+G PG  G  G DG
Sbjct: 127 LGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDG 186

Query: 79  KPGIDGLTGAKGEPGPMGIPGVKGQPGLPGP------PGLPG----------------PG 116
           + G  G  G +G PGP G  G  G PGLPG       PGL G                PG
Sbjct: 187 EAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPG 246

Query: 117 FAGPPGPPGPVGLPGE---------IGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLE 167
             G PGP GP GLPGE          G RG  G PGP GP GP GP G PG PG   G +
Sbjct: 247 ENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGA-PGAK 305

Query: 168 GSADFLCPTNC--PPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIP 225
           G A    PT    P G +GP G  G  G  G  G  G+PG  G PG KG  GA G  G P
Sbjct: 306 GEAG---PTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAP 362

Query: 226 ------GPPGPQGI---------RGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEE--- 267
                 GPPGPQG           G PG+AG KGE GP G  G  G  GA GP GEE   
Sbjct: 363 GFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKR 422

Query: 268 ---------GPRGPPGRAGEKGDEGSP---GIRGPQGI---TGPKGATGPPGINGKDGTP 312
                    GP GPPG  G  G+ G P   G+ GP+G     GP G  GP G NG  G P
Sbjct: 423 GARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRP 482

Query: 313 GTPGMKGSAGQAGQPGSPGHQGL---AGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKE 369
           G PG+ G+ G  G+PG  G QG    +G PG+ G  G PG QG  G  G+ GF GP G  
Sbjct: 483 GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 542

Query: 370 GEPGPRGE---IGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGL---P 423
           GEPG  GE    G  G+ G  G  GE G  G PGP G  G +GEQG PG  G QGL   P
Sbjct: 543 GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP 602

Query: 424 GVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYP------ 477
           G  G+ G PG  G  G+ G PG+ G  GE+G  GE G PG +G QG RG PG P      
Sbjct: 603 GPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPK 662

Query: 478 GPSGDAGAPGVQGYP---------------GPPGPRGLAGNRGVPGQPGRQGVEGRDATD 522
           G SG AG PG QG P               GP G RG  G +G  G PG+ G  G     
Sbjct: 663 GASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPI 722

Query: 523 QHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGY---------------- 566
                      + ++     +    A GA G  G  GPPGP G+                
Sbjct: 723 GPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQ 782

Query: 567 --PGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-RGHPGMPGPPGIP 623
              G++G  G PGP+G  G  G  G  G TGPKG RG +G PG  G  G  G  GPPG  
Sbjct: 783 GEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSN 842

Query: 624 GLPGRPG-QAINGKDGD---RGSPGAPGEAGRPGLPGPVGLPG 662
           G PG PG    +GKDG    RG  G PG AG PGL GP G PG
Sbjct: 843 GNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPG 885



 Score =  505 bits (1301), Expect = e-143
 Identities = 308/733 (42%), Positives = 356/733 (48%), Gaps = 128/733 (17%)

Query: 26  RGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPP----------------------- 62
           RG  GE+G PGP G  G PG+ G  G  GPPG  GPP                       
Sbjct: 68  RGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQL 127

Query: 63  ----GPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPG---- 114
               GP G  G  GP GP G PG  G  G  GEPG  G+ G  G  G PGPPG PG    
Sbjct: 128 GVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGE 187

Query: 115 ---PGFAGPPGPPGP------VGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQG 165
              PG AG  GPPGP       G PG  G++G +G PG DG  G  G PG  G  G+  G
Sbjct: 188 AGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS-PG 246

Query: 166 LEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKP---GPKGDVGASGEQ 222
             GS          PG  GP GL G +G  G  G  G  G+ G+P   GP G VG +G  
Sbjct: 247 ENGS----------PGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGP 296

Query: 223 GIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGA---IGATGPPGEEGPRGPPGRAGEK 279
           G PG PG +G  G  G  GP+G  GP G  G  G+    GA+G PG +G  G  G AG  
Sbjct: 297 GFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAP 356

Query: 280 GDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVP 339
           G  G+PG  GP+G  GP+GATGP G  G+ G PG  G KG  G  G+PG  G QG  G  
Sbjct: 357 GIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA 416

Query: 340 GQ------------------PGTKGGPGDQGEP------GPQGLPGFSGP---------- 365
           G+                  PG +G PG++G P      GP+G PG  GP          
Sbjct: 417 GEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGAN 476

Query: 366 --PGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLP 423
             PG+ GEPG  G  G  G  G  G QG+ GP G PG  GR GP G QG  G PG  G P
Sbjct: 477 GDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFP 536

Query: 424 GVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDA 483
           G KG  G PGK G +G  G PG+ GLPG+ GE G +G PGP G  G RGE G PGPSG  
Sbjct: 537 GPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQ 596

Query: 484 GAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVS 543
           G PG    PGPPG  G  G++GVPG+ G  G+ G                     E    
Sbjct: 597 GLPGP---PGPPGEGGKPGDQGVPGEAGAPGLVG------------------PRGERGFP 635

Query: 544 AKREALGAVGMMGP---PGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKR 600
            +R + GA G+ GP   PG PG  G  G  GP G PG +G PG+ G  G+ G  G  G +
Sbjct: 636 GERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPK 695

Query: 601 GEKGDPGEVG-RGHPGMPGPPGIPGLPGRPGQA-INGKDGDRGSP---------GAPGEA 649
           G++GD GE G  G PG  G  G+ G  G PG A  NG+ G+ G P         GAPGE 
Sbjct: 696 GDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGER 755

Query: 650 GRPGLPGPVGLPG 662
           G  G PGP G  G
Sbjct: 756 GETGPPGPAGFAG 768



 Score =  504 bits (1298), Expect = e-142
 Identities = 293/647 (45%), Positives = 332/647 (51%), Gaps = 51/647 (7%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
            G PGE G PGPPGP G  G  G+ G  GP G  G PG  GE G  G  G  G PG DG T
Sbjct: 510  GAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGET 569

Query: 87   GAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDG 146
            GA G PGP G  G +G+ G PGP G  G    GPPGPPG  G PG+ G+ G  G PG  G
Sbjct: 570  GAAGPPGPAGPAGERGEQGAPGPSGFQG--LPGPPGPPGEGGKPGDQGVPGEAGAPGLVG 627

Query: 147  PSGPPGPPGKPGRPGTI-----QGLEGSADFLCPTNC-----PPGMKGPPGLQGVKGHAG 196
            P G  G PG+ G PG       +GL G+     P        PPG +GPPGLQG+ G  G
Sbjct: 628  PRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERG 687

Query: 197  KRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVG 256
              GI G  G +G  G KG  GA G+ G  G  GP G  G  G  G KGE GP G  G  G
Sbjct: 688  AAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAG 747

Query: 257  AIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPG--- 313
            A GA G  GE GP GP G AG  G +G PG +G QG  G KG  G PG  G  G PG   
Sbjct: 748  ARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQG 807

Query: 314  ---TPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGP------QGLPGFSG 364
                 G KG+ G  G PG+ G  G AG  G PG+ G PG  G PGP      +G  G SG
Sbjct: 808  PTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSG 867

Query: 365  PPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKG---------EQGPPG 415
            PPG+ GEPG +G  GP G  G+ GD G  G  G PGPQG  G +G         E+G PG
Sbjct: 868  PPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG 927

Query: 416  IPGPQGLPGVKGDKGSPGKTGPRGKVGDPGV---AGLPGEKGEKGESGEPGPKGQQGVRG 472
            +PGP G PG +G  G+ G  GP G VG PG+   AG PG +G  G  G PG  G  GV+G
Sbjct: 928  LPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG 987

Query: 473  EPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKM 532
            + G  G  G  GAPG  G PGP GP G  G+RG  G  G  G  G             + 
Sbjct: 988  DRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1047

Query: 533  LQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQ-- 590
             + +  E      +   G  G+ G PGPPGP G  G  GP G  GPRG PG VG  G+  
Sbjct: 1048 DKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDG 1107

Query: 591  -------IGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPG 630
                   IG  GP+G+ GE G  G      PG PGPPG PG PG PG
Sbjct: 1108 ANGIPGPIGPPGPRGRSGETGPAGP-----PGNPGPPGPPGPPG-PG 1148



 Score =  415 bits (1066), Expect = e-116
 Identities = 247/576 (42%), Positives = 279/576 (48%), Gaps = 92/576 (15%)

Query: 26   RGPPGERGPPGPPG---PPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGI 82
            RG PGERG PG  G   P G+PG+ G DG  G  G AGPPG +G PG  G  G  G  GI
Sbjct: 632  RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 691

Query: 83   DGLTGAKG---EPGPMGIPGVKGQPGLPGPPGLPGP----GFAGPPGPPGPVGLPGEIGI 135
             G  G +G   E GP G PG  G  GL GP G PGP    G  G  GPPGP G  G  G 
Sbjct: 692  AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA 751

Query: 136  RGPKGDPGPDGPSGPPGPPGKPGRPGTI-----QGLEGSADFLCPTNCPPGMKGPPGLQG 190
             G +G+ GP GP+G  GPPG  G+PG        G +G A    P   P G  GP G  G
Sbjct: 752  PGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQG-PSGAPGPQGPTG 810

Query: 191  VKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHG 250
            V G  G RG  G PG  G PG  G VG  G  G PGPPGP G  G  G  G +G++GP G
Sbjct: 811  VTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPG 870

Query: 251  YKGMVGAIGATGPPGE------------EGPRGPPGRAGEKGDEGSPGIRGPQGI----- 293
              G  G  G  GPPGE            EGP GP G AG++G  G PG RG +G      
Sbjct: 871  RAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPG 930

Query: 294  -TGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQG 352
             +G  G  G PG +G  G PG  G  G  G AG+PG  G  G  G PG+ G  G  GD+G
Sbjct: 931  PSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRG 990

Query: 353  EPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQG 412
            E G  G PG  GPPG  G  GP G+ G +G  G +G  G  GP G  G QG QGP+G+  
Sbjct: 991  ETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGD-- 1048

Query: 413  PPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRG 472
                         KG+ G PG+ G +G  G  G+ GLPG  G  G+ G  GP G  G RG
Sbjct: 1049 -------------KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRG 1095

Query: 473  EPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKM 532
             PG  GPSG  GA G+ G  GPPGPRG +G  G  G PG                     
Sbjct: 1096 PPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNP------------------- 1136

Query: 533  LQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPG 568
                                   GPPGPPGPPG PG
Sbjct: 1137 -----------------------GPPGPPGPPG-PG 1148



 Score =  212 bits (539), Expect = 1e-54
 Identities = 122/271 (45%), Positives = 134/271 (49%), Gaps = 40/271 (14%)

Query: 19   VLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPG---PKGEPGKAGPDG 75
            ++ L   RG  G  G PGP G PG  G+ G  GD GPPG  GPPG   P GEPG+ G  G
Sbjct: 913  IVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPG 972

Query: 76   PDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGI 135
             DG PG DG  G KG+ G  G  G    PG PGPPG PGP      GP G  G  GE G 
Sbjct: 973  ADGPPGRDGAAGVKGDRGETGAVGA---PGAPGPPGSPGPA-----GPTGKQGDRGEAGA 1024

Query: 136  RGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHA 195
            +GP G  GP G  G  GP G  G                      G  G PG +G+KGH 
Sbjct: 1025 QGPMGPSGPAGARGIQGPQGPRG--------------------DKGEAGEPGERGLKGHR 1064

Query: 196  GKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMV 255
            G  G+ G P   G PGP GD GAS      GP GP G RG PG  GP G+ G +G  G +
Sbjct: 1065 GFTGLQGLP---GPPGPSGDQGAS------GPAGPSGPRGPPGPVGPSGKDGANGIPGPI 1115

Query: 256  GAIGATGPPGEEGPRGPPGRAGEKGDEGSPG 286
            G  G  G  GE GP GPPG  G  G  G PG
Sbjct: 1116 GPPGPRGRSGETGPAGPPGNPGPPGPPGPPG 1146


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score =  526 bits (1354), Expect = e-149
 Identities = 314/720 (43%), Positives = 375/720 (52%), Gaps = 73/720 (10%)

Query: 26   RGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKG---------EPGKAGPDGP 76
            RGPPG  G PG  G PG PG  G+ GD G  G  G PGPKG         EPG  G  G 
Sbjct: 798  RGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGE 857

Query: 77   DGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP-GFAGPPGPPGPVGLPGEIGI 135
             G PG+ G  G +G+ G  G+PG  G  G PGP G  G  G  G PGPPGP G PG+IG 
Sbjct: 858  QGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIG- 916

Query: 136  RGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHA 195
              P GD GP+G  G PG  G PG  G + G EG    + P   P G++G PG +G  G  
Sbjct: 917  --PPGDNGPEGMKGKPGARGLPGPRGQL-GPEGDEGPMGPPGAP-GLEGQPGRKGFPGRP 972

Query: 196  GKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMV 255
            G  G+ G+PG  G+PGP G+ G  G  G+ G PG  G +G  GM GP G  GP G  G  
Sbjct: 973  GLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHP 1032

Query: 256  GAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGIN---GKDGTP 312
            G  G  G PGE GP+GPPG  G  G  G+ G RGP+G  GP G  G  G+    G  G P
Sbjct: 1033 GMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRP 1092

Query: 313  GTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEP 372
            G PG +G AG+ G  GS G  G+ G  G PGTKG P   GEPGPQG  G  GPPG+ G  
Sbjct: 1093 GRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLP---GEPGPQGPQGPIGPPGEMGPK 1149

Query: 373  GPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSP 432
            GP G +G  G+ G+ G +G+ GP+G PG QG  G +GE G  G  GP G  G+KGD+G P
Sbjct: 1150 GPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDP 1209

Query: 433  GKTGPRGKVGD---------PGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDA 483
            G  G  G+ G          PG  G+ G +G +G+SG+ G KG+ G +G  GY G  G+ 
Sbjct: 1210 GPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEM 1269

Query: 484  GAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDAT---DQH---IVDVALKMLQEQL 537
            G PG  G PG PGP+G  G+ G  G PGR G +G       D H   +  +     + + 
Sbjct: 1270 GVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEK 1329

Query: 538  AEVAVSAKREA-------LGAVGMMGPPGPPGPPGY------------PGKQGPHGHPGP 578
             E     K E         G VG  G  G PG PGY            PG+QG  GHPGP
Sbjct: 1330 GEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGP 1389

Query: 579  RGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-RGHPGMPGPPGI------------PGL 625
            RG PG  G+ G     GPKGK+G+ G PG  G +G  G+PGP G+             GL
Sbjct: 1390 RGWPGPKGSKGA---EGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGL 1446

Query: 626  PGRPGQA-INGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASARLTEPG 684
            PGR GQA   G+ GD G PG  G AG+ G PG  GLPG   P    G S     +L  PG
Sbjct: 1447 PGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESG-LPGQLGPPG 1505



 Score =  513 bits (1320), Expect = e-145
 Identities = 298/696 (42%), Positives = 363/696 (52%), Gaps = 87/696 (12%)

Query: 27   GPPGERGPPGPPGPPGV---------PGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPD 77
            GP G+ GP GPPG PG+         PG  G+DG  G PG  G PGP GE G  G  G  
Sbjct: 943  GPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLV 1002

Query: 78   GKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPG-PGFAGPPGPPGPVGLPGEIGIR 136
            G+PGI G  G +G  GP G+PG KG  G PG PG  G PG  GP GPPG  G PG  G +
Sbjct: 1003 GEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAK 1062

Query: 137  GPKGDPGPDGPSG---------PPGPPGKPGRPGTIQGLEGSADFLCPTNCP--PGMKGP 185
            G +G  GPDGP+G         PPGP G+PGRPG  QG+ G    L     P  PG  GP
Sbjct: 1063 GRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQ-QGVAGERGHLGSRGFPGIPGPSGP 1121

Query: 186  PGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPG------------------- 226
            PG +G+ G  G +G  G  G  G+ GPKG  GA GE G+PG                   
Sbjct: 1122 PGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGL 1181

Query: 227  --------------PPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGP 272
                          P GP G++G  G  GP GE G  G +G++G  G  GPPG  G RGP
Sbjct: 1182 IGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGP 1241

Query: 273  PGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGH 332
             G++G++G++G  G +G +G  G  G  G PG  G  GTPG  G +GS G  G PG  G 
Sbjct: 1242 EGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGA 1301

Query: 333  QGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGK-EGEPGPRGEIGPQGIMGQKGDQG 391
            QG  G+ G  G KG  G  G PGP+G  G  G  GK EG PGP G+ GP G  G +G+ G
Sbjct: 1302 QGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPG 1361

Query: 392  ERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPG------ 445
            + G  GQ G QG +G  G+QG PG PGP+G PG KG KG+ G  G +GK G PG      
Sbjct: 1362 DPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQG 1421

Query: 446  VAGLPGEKGE---------------KGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQG 490
            + GLPG +G                 G  G+ G +G+QG  G+PG  GP+G  G PGV G
Sbjct: 1422 LQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAG 1481

Query: 491  YPGPPGPRGLAGNRGVPGQ---PGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKRE 547
             PG  GP G  G  G+PGQ   PG++G EGR     +  +   K       E+       
Sbjct: 1482 LPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFP---- 1537

Query: 548  ALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPG 607
              G  G+ GP GPPG  G+ G QGP G PG  G  GIVG +G +G +G  G +G+KG  G
Sbjct: 1538 --GMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRG 1595

Query: 608  EVG-RGHPGMPGPPGIPGLPGRPGQAINGKDGDRGS 642
            + G +G  G PGP G PG PG PG  I  +  D G+
Sbjct: 1596 DWGLQGPRGPPGPRGRPGPPGPPGGPIQLQQDDLGA 1631



 Score =  439 bits (1128), Expect = e-123
 Identities = 276/702 (39%), Positives = 329/702 (46%), Gaps = 157/702 (22%)

Query: 85   LTGAKGEPGPMGIPGVKGQPGLPGPPGLPG----PGFAGPPGPPGPVG---LPGEIGIRG 137
            L G+   P  MG PG KG  GLPGPPGLPG    PG  GP GPPGP G   LPG  G +G
Sbjct: 614  LAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKG 673

Query: 138  PKGDPG------PDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCP-----PGMKGPP 186
             KGDPG       DG  G  G PG  G PG   G +G   +  P   P     PG +G P
Sbjct: 674  QKGDPGLSPGKAHDGAKGDMGLPGLSGNPGP-PGRKGHKGYPGPAGHPGEQGQPGPEGSP 732

Query: 187  GLQGVKGHAGKRGILGDPGHQGK------PGPKGDVGASGEQGIPGPPGPQGIRGYPGMA 240
            G +G  G  G  G +GDPG +G       PG  G  G+ GE+G+PG PG +G  G PG  
Sbjct: 733  GAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFP 792

Query: 241  GPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGAT 300
            G  GE GP G  G  G +G  GPPG  G  G  G  G  G  G  G++G  G  G  G  
Sbjct: 793  GVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLK 852

Query: 301  GPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLP 360
            G  G  G  G  G PG +G  G  G PG PG +G  G  G+ G KG  G  G PGP+G P
Sbjct: 853  GDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFP 912

Query: 361  GFSGPPGKEGE------------PGPRGEIGPQ--------------------------- 381
            G  GPPG  G             PGPRG++GP+                           
Sbjct: 913  GDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRP 972

Query: 382  ---GIMGQKGDQGERGP------------VGQPGPQGRQGPKGEQGPPGIPGPQGL---P 423
               G+ G+ GD G  GP            VG+PG  G +G +G  GPPG+PGP+G    P
Sbjct: 973  GLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHP 1032

Query: 424  GVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDA 483
            G+ G  G+PG+ GP+G  G  G  G+ G KG +G  G  GP G+QG RG  G PGP G  
Sbjct: 1033 GMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRP 1092

Query: 484  GAPGVQ------------GYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALK 531
            G PG Q            G+PG PGP G  G +G+PG+PG QG +G              
Sbjct: 1093 GRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQG-------------- 1138

Query: 532  MLQEQLAEVAVSAKREALGAVGMMGPPGPP---GPPGYPGKQGPHGHPGPRGVPGIVGAV 588
                             +G  G MGP GPP   G PG PG+ G  G  GP G PG  G +
Sbjct: 1139 ----------------PIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLI 1182

Query: 589  GQIGN---------TGPKGKRGEKGDPGEVGR----------GHPGMPGPPGIPGLPGRP 629
            GQ G           GP G +G++GDPG  G           G  G PGPPG+ G+ G  
Sbjct: 1183 GQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPE 1242

Query: 630  GQAINGKDGDRGSPGAP---------GEAGRPGLPGPVGLPG 662
            G+  +GK G++G  GA          GE G PG PGP G PG
Sbjct: 1243 GK--SGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPG 1282



 Score =  355 bits (911), Expect = 8e-98
 Identities = 283/816 (34%), Positives = 333/816 (40%), Gaps = 174/816 (21%)

Query: 8    PRSLLVLLQVVVLALAQIRGPPGERGPPGP---PGPPGVPGSDG-----------IDGDN 53
            P S  V  +V   A   I+  PG   PP P   P PP    S             I    
Sbjct: 409  PTSRPVPARVSRPAEKPIQRNPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEAKITSHA 468

Query: 54   GPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLP 113
              P  A     K  P  A    P   PG    T     P    +P   G       P +P
Sbjct: 469  SKPASARTSTHKPPPFTALSSSPAPTPGSTRST----RPPATMVPPTSGTSTPRTAPAVP 524

Query: 114  GPGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFL 173
             PG A P G   P+G        GPK  P    P  P    GK  R   +  L       
Sbjct: 525  TPGSA-PTGSKKPIGSEASKKA-GPKSSPRKPVPLRP----GKAARDVPLSDLTTRPS-- 576

Query: 174  CPTNCPPGMKGPPGL-------------QGVKGHA--GKRGILGDPGHQGKPGPKGDVGA 218
             P    P  +  P L                 G++     G    P   G PGPKGD G 
Sbjct: 577  -PRQPQPSQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCG- 634

Query: 219  SGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGE 278
                 +PGPPG  G+ G PG  GP+G  GP+G  G+ G               PPG  G+
Sbjct: 635  -----LPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPG---------------PPGAKGQ 674

Query: 279  KGDEG-SP-----GIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGH 332
            KGD G SP     G +G  G+ G  G  GPPG  G  G PG  G  G  GQ G  GSPG 
Sbjct: 675  KGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGA 734

Query: 333  Q---------------------------GLAGVPGQPGTKGGPGDQGEPGPQGLPGF--- 362
            +                           GL G+PG  G +G PG  G+ G  G+PGF   
Sbjct: 735  KGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGV 794

Query: 363  ---SGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQ---------GPKGE 410
                GPPG +G PG  G  GP G+ G  GD G  GP+G PGP+G +         G KG+
Sbjct: 795  FGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGD 854

Query: 411  QGPPGIPGPQGLPGVKGDKGSP---------GKTGPRGKVGDPGVAGLPGEKGEK---GE 458
            +G  G+PG  G PG +GDKGS          GK GP GKVGD G  G PG  G +   G+
Sbjct: 855  KGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGD 914

Query: 459  SGEPGPKGQQGVRGEP---GYPGPSGDAGAPGVQGYPGPPGPRGL---AGNRGVPGQPGR 512
             G PG  G +G++G+P   G PGP G  G  G +G  GPPG  GL    G +G PG+PG 
Sbjct: 915  IGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGL 974

Query: 513  QGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPP-------- 564
             GV+G          V  +     +  V         G  GMMGPPG PGP         
Sbjct: 975  DGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGM 1034

Query: 565  ----GYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGP------KGKRGEKGDPGEVG---- 610
                G PG+ GP G PG RG PG+ GA G+ G  GP      +G RG KG PG  G    
Sbjct: 1035 PGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGR 1094

Query: 611  ---------------RGHPGMP---GPPGIPGLPGRPG----QAINGKDGDRGSPGAPGE 648
                           RG PG+P   GPPG  GLPG PG    Q   G  G+ G  G PG 
Sbjct: 1095 PGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGA 1154

Query: 649  AGRPGLPGPVGLPGFCEPAACLGASAYASARLTEPG 684
             G PGLPG  G+ G   P    G       R  EPG
Sbjct: 1155 VGEPGLPGEAGMKGDLGPLGTPGEQGLIGQR-GEPG 1189



 Score =  276 bits (707), Expect = 4e-74
 Identities = 174/407 (42%), Positives = 197/407 (48%), Gaps = 40/407 (9%)

Query: 25   IRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDG 84
            +RGP G+ G  G  G  G  G+ G  G  G  G  G PGP G PG  G  G  G  G  G
Sbjct: 1238 VRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPG 1297

Query: 85   LTGAKGEPGPMGIPGVKGQPGLPGPPGLPG-------PGFA-GPPGPPGPVGLPGEIGIR 136
              GA+GEPG  G  G KG  G  GPPG  G        G A GPPGPPG  G  G+ G R
Sbjct: 1298 RMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDR 1357

Query: 137  GPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAG 196
            G  GDPG  G  G  G  GKPG+ G   G  G          P G  GP G +G +G  G
Sbjct: 1358 GEPGDPGYPGQEGVQGLRGKPGQQGQ-PGHPG----------PRGWPGPKGSKGAEGPKG 1406

Query: 197  KRGILGDPGH------QGKPGPKGDVGASGEQGIPGP---PGPQGIRGYPGMAGPKGETG 247
            K+G  G PG       QG PGP+G VG  G +GI GP   PG  G  G  G  G  G+ G
Sbjct: 1407 KQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPG 1466

Query: 248  PHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGING 307
            P G  G  G  G  G PG +GP G  G +G  G  G PG RG +G TG  G  G PG  G
Sbjct: 1467 PMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKG 1526

Query: 308  KDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPG 367
            + G  G  G  G AG  G  G PG  G  G+ G  G  G  G +G  GP G+ G SG PG
Sbjct: 1527 QPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPG 1586

Query: 368  KEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPP 414
             +G+ G RG+ G Q            GP G PGP+GR GP G  G P
Sbjct: 1587 PKGDKGSRGDWGLQ------------GPRGPPGPRGRPGPPGPPGGP 1621



 Score =  240 bits (612), Expect = 4e-63
 Identities = 140/328 (42%), Positives = 169/328 (51%), Gaps = 32/328 (9%)

Query: 22   LAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPG 81
            LA   G  G  GP GPPGP G  G  G DG        GPPGP G+ G  G  G  G+PG
Sbjct: 1307 LAGYDGHKGIVGPLGPPGPKGEKGEQGEDGK-----AEGPPGPPGDRGPVGDRGDRGEPG 1361

Query: 82   IDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP----GFAGPPGPPGPVGLPGEIGIRG 137
              G  G +G  G  G PG +GQPG PGP G PGP    G  GP G  G  G PG  G++G
Sbjct: 1362 DPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQG 1421

Query: 138  PKGDPGP---------DGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGL 188
             +G PGP         +G +GP G PG+ G+ G  QG +G        +  PG  GP G 
Sbjct: 1422 LQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQ-QGEQGD-------DGDPGPMGPAGK 1473

Query: 189  QGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGP 248
            +G  G AG  G  G PG +G+ G  G +G  G++G  G  G  G +G PG  G  G++G 
Sbjct: 1474 RGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGE 1533

Query: 249  HGYKGMVGAIGATGPPGE------EGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGP 302
             G+ GM G  G  GPPG+      +GPRGPPG  G++G  G  GI GP G+ GPKG  G 
Sbjct: 1534 MGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGS 1593

Query: 303  PGINGKDGTPGTPGMKGSAGQAGQPGSP 330
             G  G  G  G PG +G  G  G PG P
Sbjct: 1594 RGDWGLQGPRGPPGPRGRPGPPGPPGGP 1621



 Score =  134 bits (337), Expect = 3e-31
 Identities = 72/144 (50%), Positives = 84/144 (58%), Gaps = 7/144 (4%)

Query: 19   VLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDG 78
            V  L   +GPPG +G  G PG  G PG  G +G  G PG  G PG KG+PG +   G  G
Sbjct: 1479 VAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDS---GEMG 1535

Query: 79   KPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPG-PGFAGPPGPPGPVGLPGEIGIRG 137
             PG+ GL G KG PG +G  G++G     GPPGL G  G  GP G  GP GLPG  G +G
Sbjct: 1536 FPGMAGLFGPKGPPGDIGFKGIQGP---RGPPGLMGKEGIVGPLGILGPSGLPGPKGDKG 1592

Query: 138  PKGDPGPDGPSGPPGPPGKPGRPG 161
             +GD G  GP GPPGP G+PG PG
Sbjct: 1593 SRGDWGLQGPRGPPGPRGRPGPPG 1616


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score =  523 bits (1347), Expect = e-148
 Identities = 316/697 (45%), Positives = 365/697 (52%), Gaps = 98/697 (14%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDG--PDGKPGIDG 84
            G PG  G PG PGP G PGS G+ G+ GPPG  G PG +G+ G  GP G  P G  G  G
Sbjct: 559  GSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKG 618

Query: 85   LTGAKGEPGPMGIPGVKGQPG----LPGPPG---LPG-PGFAGP------PGPPGPVGLP 130
              G  G PG  G+PG KG+PG    LPGPPG   LPG PGF GP      PG PG  GLP
Sbjct: 619  QAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLP 678

Query: 131  GE--------IGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGM 182
            GE        IG  GP G  G DG  G  GPPG PGRPG   GL G+          PG+
Sbjct: 679  GEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPG-FNGLPGN----------PGV 727

Query: 183  KGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASG---EQGIPGPPGPQGIRGYPGM 239
            +G  G  GV G  G +G+ G PG  G PG KG +G  G   E G  GPPG QGIRG PG 
Sbjct: 728  QGQKGEPGV-GLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGP 786

Query: 240  AGPKGETGPHGYKGMVGAIGATGPPGEEGP---RGPPGRAGEKGDEGSPGIRGPQGITGP 296
             G  G  G  G  G +G  GA GPPG +GP    GPPG  GEKG  G PG+  P G  G 
Sbjct: 787  PGLPGSVGSPGVPG-IGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMP-GPKGD 844

Query: 297  KGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKG---GPGDQGE 353
            KGA G PGI G+ G PG PG +G+ G  G PGS G  G+ G PGQPG+ G    PG  GE
Sbjct: 845  KGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGE 904

Query: 354  PGPQGLPGFSGPPGKEGEPGPRGEIGPQG------------IMGQKGDQGERGPVG---- 397
             G  G PG SGP G  G  G +G++G  G            + GQKGDQGE+G +G    
Sbjct: 905  KGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGE 964

Query: 398  -----QPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGE 452
                  PG  G  G  G+ G PG PGP+G PG+ G  G+PG  GP+G VG     GLPG 
Sbjct: 965  KGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGG---MGLPGT 1021

Query: 453  KGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGR 512
             GEKG  G PGP+G  G+ G+ G  G  G AG PG+ G PG  G +G  G  G PG PG 
Sbjct: 1022 PGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGI-GIPGLRGEKGDQGIAGFPGSPGE 1080

Query: 513  QGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGP 572
            +G +G                      + +     + G  G  G  G PG PG PG++G 
Sbjct: 1081 KGEKG---------------------SIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGD 1119

Query: 573  HGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQA 632
             G PG  G+PG+ G  G  G  GP G  G+KG+PG    G PG  G  G PGLPGR    
Sbjct: 1120 KGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGS--DGIPGSAGEKGEPGLPGRGFPG 1177

Query: 633  INGKDGDRGSPGA---PGEAGRPGLPGPVGLPGFCEP 666
              G  GD+GS G    PG AG PG+PG  G  GF  P
Sbjct: 1178 FPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGP 1214



 Score =  518 bits (1335), Expect = e-147
 Identities = 316/697 (45%), Positives = 371/697 (53%), Gaps = 89/697 (12%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGE---PGKAGPDGPDGKPGID 83
            GP G+RG PG PG PG+PG  G  G  G  G  GPPGPKG    PG  GP G  G+PG +
Sbjct: 661  GPQGDRGFPGTPGRPGLPGEKGAVGQPGI-GFPGPPGPKGVDGLPGDMGPPGTPGRPGFN 719

Query: 84   GLTG------AKGEPGPMGIPGVKGQPGLPGPPGLPGP-GFAGPPGPPGPVGLPGEIGIR 136
            GL G       KGEPG +G+PG+KG PGLPG PG PG  G  G PG PG  G  G  G++
Sbjct: 720  GLPGNPGVQGQKGEPG-VGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQ 778

Query: 137  GPKGDPGPDGPSGPPGPPGKPG-RPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHA 195
            G +G+PGP G  G  G PG PG  P   +G             PPG +GPPGL G  G  
Sbjct: 779  GIRGEPGPPGLPGSVGSPGVPGIGPPGARG-------------PPGGQGPPGLSGPPGIK 825

Query: 196  GKRGILGDPGHQGKPGPKGDVGA------SGEQGIPGPPGPQGIRGYPGMAGPKGETGPH 249
            G++G  G PG    PGPKGD GA      +G+ G+PG PG QG  G PG  G KGE G  
Sbjct: 826  GEKGFPGFPGLD-MPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVM 884

Query: 250  GYKGMVGA---IGATGPPGEEG---------PRGPPGRAGEKGDEGSPG----------- 286
            G  G  G+   +GA G PGE+G         PRG PG  G+KGD G PG           
Sbjct: 885  GTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMG 944

Query: 287  -IRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTK 345
             ++G +G  G KG  GP G  G  G PGTPG+ G  GQAGQPG PG +G  G+ G PG  
Sbjct: 945  SMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAP 1004

Query: 346  GGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGP--VGQPGPQG 403
            G PG +G  G  GLPG  G  G  G PGP+G  G  G  G KG++G+ GP  +G PG +G
Sbjct: 1005 GLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRG 1064

Query: 404  RQGPKGEQGPPGIPGPQGLP---GVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEK---G 457
             +G +G  G PG PG +G     G+ G  GSPG  G  G VG PG  GLPGEKG+K   G
Sbjct: 1065 EKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPG 1124

Query: 458  ESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAG--NRGVPGQPGRQGV 515
              G PG KG+ G+ G PG  GP+G  G PG  G PG  G +G  G   RG PG PG +G 
Sbjct: 1125 LDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGD 1184

Query: 516  EGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGK-----Q 570
            +G         +V    L        +   +   G  G MGPPGP G PG PG      +
Sbjct: 1185 KGSKG------EVGFPGL---AGSPGIPGSK---GEQGFMGPPGPQGQPGLPGSPGHATE 1232

Query: 571  GPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-RGHPGMPGPPGIPGLPGRP 629
            GP G  GP+G PG+ G  G +G  G  G  G KGD G  G  G PG+PGP G PG  G P
Sbjct: 1233 GPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMP 1292

Query: 630  G----QAINGKDGDRGSPGAPGEAGRPGLPGPVGLPG 662
            G      I G  GD G PG PG  G  GLPG  G+ G
Sbjct: 1293 GIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKG 1329



 Score =  517 bits (1332), Expect = e-146
 Identities = 328/821 (39%), Positives = 385/821 (46%), Gaps = 186/821 (22%)

Query: 19  VLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDG 78
           V+    ++GP G +GPPG  G  G PG  G  G  GPPG +G PG  G PG  G DGP G
Sbjct: 59  VIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPG 118

Query: 79  KPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPG------------------------ 114
            PGI G  G KGE GP+G PG+ G  G PGPPGLPG                        
Sbjct: 119 PPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFP 178

Query: 115 --------------------PGFAGPPGPPGPVGLPGEIG-----IRGPKGDPGPDGPSG 149
                               PGF GPPGPPGP G PGE G      +GPKGD G  G SG
Sbjct: 179 GIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSG 238

Query: 150 PPGPP-----------------GKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVK 192
           PPG P                 G+ G PG  QG+ G  +   P    PG +G PG  G K
Sbjct: 239 PPGVPGQAQVQEKGDFATKGEKGQKGEPG-FQGMPGVGEKGEPGK--PGPRGKPGKDGDK 295

Query: 193 GHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPP---------GPQGIRGYPGMAGPK 243
           G  G  G  G+PG+ G  G +G  G  GE G PGPP         G +G RGYPG  GP+
Sbjct: 296 GEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPR 355

Query: 244 GETGPHGYKGMVGAIGATG--PPGEEGPRGPPGRAGEKGDEGSP-----------GIRGP 290
           GE GP G+ G+ G  G  G   PG+ G  G PG  GEKGD G P           G+ GP
Sbjct: 356 GEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGP 415

Query: 291 QGITGPKG-----------ATGPPGINGKDGTPGTPGMKGSAGQAGQ------------- 326
            G  GP G             GPPG  G  G PG PG  G  G+ GQ             
Sbjct: 416 PGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGY 475

Query: 327 ---PGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGI 383
              PG  G  G  G PGQPG KG  G  G  G  G+PG  G PG  G+PG +GE G    
Sbjct: 476 RGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYF 535

Query: 384 -MGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLP---GVKGDKGSPGKT---- 435
            +  KGD+G+ G  GQPG  GR G  G  G PG+PGP+G P   G+KG++G PG      
Sbjct: 536 DLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPG 595

Query: 436 -------------GPRGKVGDPGVAGLPGEKGE------KGESGE----PGPKGQQGVRG 472
                        GP G +GD G AG PG  G       KGE G+    PGP G +G+ G
Sbjct: 596 SRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPG 655

Query: 473 EPGYPGPSGDAGAPGVQ-----------------GYPGPPGPR---GLAGNRGVPGQPGR 512
            PG+PGP GD G PG                   G+PGPPGP+   GL G+ G PG PGR
Sbjct: 656 SPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGR 715

Query: 513 QGVEGRDAT-----DQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYP 567
            G  G          +    V L  L+       +       G++G+ G PG  G  G P
Sbjct: 716 PGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPP 775

Query: 568 GKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGI---PG 624
           G QG  G PGP G+PG VG+ G +   GP G RG  G     G+G PG+ GPPGI    G
Sbjct: 776 GLQGIRGEPGPPGLPGSVGSPG-VPGIGPPGARGPPG-----GQGPPGLSGPPGIKGEKG 829

Query: 625 LPGRPGQAINGKDGDRGS---PGAPGEAGRPGLPGPVGLPG 662
            PG PG  + G  GD+G+   PG  G++G PGLPG  G PG
Sbjct: 830 FPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPG 870



 Score =  509 bits (1312), Expect = e-144
 Identities = 315/740 (42%), Positives = 370/740 (50%), Gaps = 113/740 (15%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
            G  GE+G PG PG PG PG  G  G  G  G+AGPPGP G     GP G  G+ G  G  
Sbjct: 293  GDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTP 352

Query: 87   GAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPK--GDPGP 144
            G +GEPGP G PG+   PG PGPPGLP PG AG PG PG  G  G+ G  G    G  G 
Sbjct: 353  GPRGEPGPKGFPGL---PGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGR 409

Query: 145  DGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDP 204
            DG  GPPG PG PG+PG   G+       C    PPG +GPPG+ G  G  G+ G  G  
Sbjct: 410  DGLPGPPGSPGPPGQPGYTNGIVE-----CQPG-PPGDQGPPGIPGQPGFIGEIGEKGQK 463

Query: 205  GHQ-------GKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGA 257
            G         G  GP G  G  GE G PG PG +G RG PG  G  G  GP G  G++G 
Sbjct: 464  GESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQ 523

Query: 258  IGATGPPGE----------EGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGING 307
             GA G PGE          +G  G PG+ G  G  GSPG  G  G+ GPKG+ G  G+ G
Sbjct: 524  PGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKG 583

Query: 308  KDGTPGTPGMKGSAGQAGQPGSPGH--------QGLAGVPGQPGTKGGPGDQGEPGP--- 356
            + G PG  G  GS G  G PG PG+        +G AG PG PG+ G PG +GEPG    
Sbjct: 584  ERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVP 643

Query: 357  -QGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPG--------PQGRQGP 407
              G PG  G PG  G PGP+G+ G  G  G+ G  GE+G VGQPG        P+G  G 
Sbjct: 644  LPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGL 703

Query: 408  KGEQGPPGIPGPQGL------PGVKGDKGSPGK--TGPRGKVGDPGVAGLPGEKGEKGES 459
             G+ GPPG PG  G       PGV+G KG PG    G +G  G PG+ G PGEKG  G  
Sbjct: 704  PGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVP 763

Query: 460  GEPG------PKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQ 513
            G PG      P G QG+RGEPG PG  G  G+PGV G  GPPG RG  G +G PG  G  
Sbjct: 764  GVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGI-GPPGARGPPGGQGPPGLSGPP 822

Query: 514  GVEGR----------------DATDQHIVDVA----LKMLQEQLAEVAVSAKREALGAVG 553
            G++G                 D   Q +  +     L  L  Q     +     + G +G
Sbjct: 823  GIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMG 882

Query: 554  MMGPPGPPGPPG------YPGKQGPHGHPG---PRGVPGIVGAVGQIGNTGPKGK----- 599
            +MG PG PG PG       PG++G HG PG   PRG PG+ G  G +G  G  G      
Sbjct: 883  VMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVD 942

Query: 600  ----RGEKGDPGEVGR----GHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGR 651
                +G+KGD GE G+    G  G  G PG PG+PG+ GQA        G PG PG  G 
Sbjct: 943  MGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQA--------GQPGQPGPKGD 994

Query: 652  PGLPGPVGLPGFCEPAACLG 671
            PG+ G  G PG   P   +G
Sbjct: 995  PGISGTPGAPGLPGPKGSVG 1014



 Score =  489 bits (1260), Expect = e-138
 Identities = 318/758 (41%), Positives = 363/758 (47%), Gaps = 127/758 (16%)

Query: 13  VLLQVVVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPP---------- 62
           +L  V  + L   RG PG  G PGPPG PG+ G  G  G  GPPG  GPP          
Sbjct: 162 ILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMG 221

Query: 63  ----GPKGEPGKAGPDGPDGKPG-----------IDGLTGAKGEPGPMGIPGV--KGQPG 105
               GPKG+ G  G  GP G PG             G  G KGEPG  G+PGV  KG+PG
Sbjct: 222 LSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPG 281

Query: 106 LPGPPGLPG----PGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGP----------- 150
            PGP G PG     G  G PG PG  G PG IG +GP+G+ G  GP GP           
Sbjct: 282 KPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLG 341

Query: 151 -------PGPPGKPGRPGTIQGLEGSADFLCPTNCP-PGMKGPPGLQGVKGHAGKRG--- 199
                  PG PG  G PG  +G  G      P   P PG  G PG  G +G  G RG   
Sbjct: 342 EKGERGYPGTPGPRGEPGP-KGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPG 400

Query: 200 --ILGDPGHQGKPGPKGDVGASGEQGI--------PGPPGPQGIRGYPGMAGPKGETGPH 249
             + G  G  G PGP G  G  G+ G         PGPPG QG  G PG  G  GE G  
Sbjct: 401 TSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEK 460

Query: 250 GYKGMVGAI----GATGPPGEEGPRGP---PGRAGEKGDEGSPGIRGPQGITGPKGATGP 302
           G KG    I    G  GPPG +GP G    PG+ G KGD G PG  G  G+ GP+G    
Sbjct: 461 GQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGT--- 517

Query: 303 PGINGKDGTPGTPG-------MKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPG 355
           PG+ G+ G  G PG       +KG  G  G PG PG  G AG PG+ G  G PG +G PG
Sbjct: 518 PGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPG 577

Query: 356 PQGLPGFSGPPGKEGEPGPRGEIGP-----QGIMGQKGDQGERGPVGQPGPQGRQGPKGE 410
             GL G  GPPG  G PG RG+ GP      G  G  GD+G+ G  G PG  G  GPKGE
Sbjct: 578 SVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGE 637

Query: 411 QGP-PGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGES--GEPGPKGQ 467
            G    +PGP G  G+ G  G PG  G RG  G PG  GLPGEKG  G+   G PGP G 
Sbjct: 638 PGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGP 697

Query: 468 QGVRGEPGYPGPSGDAGAPGVQGYPGPPGPR--------GLAGNRGVPGQPGRQGVEGRD 519
           +GV G PG  GP G  G PG  G PG PG +        GL G +G+PG PG  G  G  
Sbjct: 698 KGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEK 757

Query: 520 ATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHP--G 577
            +               +    V  +  A+G  G+ G  G PGPPG PG  G  G P  G
Sbjct: 758 GS---------------IGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIG 802

Query: 578 PRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG------------RGHPGMPGPPGIPGL 625
           P G  G  G  G  G +GP G +GEKG PG  G            +G PG+ G  G+PGL
Sbjct: 803 PPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGL 862

Query: 626 PGRPG-QAINGKDGDRGSPGAPGEAGRPGLPGPVGLPG 662
           PG+ G   I G  G +G  G  G  G+PG PGPVG PG
Sbjct: 863 PGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPG 900



 Score =  473 bits (1218), Expect = e-133
 Identities = 290/674 (43%), Positives = 342/674 (50%), Gaps = 107/674 (15%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAG--PPGPKGEPGKAGPDGPDGKPGIDG 84
            GPPG RGPPG  GPPG+ G  GI G+ G PG  G   PGPKG+ G  G  G  G+ G+ G
Sbjct: 802  GPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPG 861

Query: 85   LTGAKGEPGPMGIPGVKGQPGLPGPPGLPG-PGFAGPPGPPGPVGLPGEIGIRGPKGDPG 143
            L G +G PG  G PG KG+ G+ G PG PG PG  G PG PG  G  G  G  GP+GDPG
Sbjct: 862  LPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPG 921

Query: 144  PDGPSGPPGPPGKPGRPGTI--------QGLEGSADFLCP-----TNCPPGMKGPPGLQG 190
              G  G  G PGKPG    +        +G +G    + P     +   PG  G PG  G
Sbjct: 922  LKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDG 981

Query: 191  VKGHAGKRGILGDPGHQGKPG------PKGDVGASG------EQGIPGPPGPQGIRGYPG 238
              G  G+ G  GDPG  G PG      PKG VG  G      E+G+PG PGPQG  G PG
Sbjct: 982  QAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPG 1041

Query: 239  MAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKG 298
              G KGE G  G  G +G  G  G  G++G  G PG  GEKG++GS GI G  G  G KG
Sbjct: 1042 DKGAKGEKGQAGPPG-IGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKG 1100

Query: 299  ATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQG 358
            +   PG  G  G+PG PG KG  G  G  G PG +G AG+PG PG  G  G +GEPG  G
Sbjct: 1101 S---PGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDG 1157

Query: 359  LPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPG 418
            +PG +G  G+ G PG RG  G  G  G KG +GE G  G  G  G  G KGEQG  G PG
Sbjct: 1158 IPGSAGEKGEPGLPG-RGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPG 1216

Query: 419  PQGLPGV--------------KGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGP 464
            PQG PG+              +G +G PG  G  G +G PG+ G+ G KG+KG  G PG 
Sbjct: 1217 PQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGA 1276

Query: 465  KGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQH 524
             G  G +G+PG+ G  G  G+PG+ G  G  GP G+ G +G  G PG QG++G D  DQ 
Sbjct: 1277 PGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKG-DQGDQG 1335

Query: 525  IVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGP-------PGYPGKQGPHGH-- 575
            +                        GA G+ GPPGPPGP       PG PG +GP G   
Sbjct: 1336 VP-----------------------GAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKG 1372

Query: 576  -------------------PGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGM 616
                               PGP G+PG  GA GQ G  GP G  G         RG PG 
Sbjct: 1373 LQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGP--------RGFPGP 1424

Query: 617  PGPPGIPGLPGRPG 630
            PGP G+PG  G PG
Sbjct: 1425 PGPDGLPGSMGPPG 1438



 Score =  466 bits (1200), Expect = e-131
 Identities = 316/759 (41%), Positives = 368/759 (48%), Gaps = 138/759 (18%)

Query: 48  GIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQ---- 103
           G+ G  G  G  G  G  G PG  GP+GP G PG       KG+ G  G+PG KG     
Sbjct: 43  GVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPG------QKGDTGEPGLPGTKGTRGPP 96

Query: 104 --PGLPGPPGLPG-PGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGR- 159
              G PG PGLPG PG  GPPGPPG  G  G  G RGP G PG  G +G PGPPG PG  
Sbjct: 97  GASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMK 156

Query: 160 --PGTIQG------LEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPG 211
             PG I G      L+G   F       PG  GPPGL G++G  G  G  G PG  G PG
Sbjct: 157 GDPGEILGHVPGMLLKGERGF----PGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPG 212

Query: 212 PKGDVGASG--EQGIPGPPGPQGIRGYPGM--------------AGPKGETGPHGYKGMV 255
           P G+ G  G   QG  G  G QG+ G PG+               G KG+ G  G++GM 
Sbjct: 213 PPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMP 272

Query: 256 GAIGATGPPGEEGPRGPPGRAGEKGDEGSPGI------------RGPQGITGPKGATGPP 303
           G +G  G PG+ GPRG PG+ G+KG++GSPG             +GPQG  G  G  GPP
Sbjct: 273 G-VGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPP 331

Query: 304 GI---------NGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAG--VPGQPGTKGGPGDQG 352
           GI          G+ G PGTPG +G  G  G PG PG  G  G  VPGQ G  G PG++G
Sbjct: 332 GIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERG 391

Query: 353 E-----------PGPQGLPGFSGPPGKEG--------------EPGPRGEIGPQGIMGQK 387
           E           PGP G  G  GPPG  G              +PGP G+ GP GI GQ 
Sbjct: 392 EKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQP 451

Query: 388 GDQGERGPVGQPGP-------QGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGK 440
           G  GE G  GQ G         G +GP G QGPPG  G  G PG KGD+G PG+ G  G 
Sbjct: 452 GFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGV 511

Query: 441 VGDPGVAGLPGEKGEKGESGE----PGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPG 496
            G  G  GL G+ G KGE GE       KG +G  G PG PG +G AG+PG  G+PG PG
Sbjct: 512 PGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPG 571

Query: 497 PR------GLAGNRGVPGQ---PGRQGVEGRDATDQH-----IVDVALKMLQEQLAEVAV 542
           P+      GL G RG PG    PG +G  G      +     I D              +
Sbjct: 572 PKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGL 631

Query: 543 -SAKREALGAVGMMGPPGP---PGPPGYPGKQGPHGHPGPRGVPGI---VGAVGQ--IGN 593
              K E    V + GPPG    PG PG+PG QG  G PG  G PG+    GAVGQ  IG 
Sbjct: 632 PGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGF 691

Query: 594 TGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGD--------RGSPGA 645
            GP G +G  G PG++  G PG PG PG  GLPG PG  + G+ G+        +G PG 
Sbjct: 692 PGPPGPKGVDGLPGDM--GPPGTPGRPGFNGLPGNPG--VQGQKGEPGVGLPGLKGLPGL 747

Query: 646 PGEAGRPGLPGPVGLPGFCEPAACLGASAYASARLTEPG 684
           PG  G PG  G +G+PG       +G       R  EPG
Sbjct: 748 PGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIR-GEPG 785



 Score =  409 bits (1052), Expect = e-114
 Identities = 234/498 (46%), Positives = 276/498 (55%), Gaps = 31/498 (6%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
            GP GE+G  G PG PGVPG DG  G  G PG  G PG  G PG  G  GP G  G  GL 
Sbjct: 960  GPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLP 1019

Query: 87   GAKGEPGPMGIPGVKGQPGLPGPPGLPGP-GFAGPPGP--PGPVGLPGEIGIRGPKGDPG 143
            G  GE G  GIPG +G PGLPG  G  G  G AGPPG   PG  G  G+ GI G  G PG
Sbjct: 1020 GTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPG 1079

Query: 144  PDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCP--PGMKGPPGLQGVKGHAGKRGIL 201
              G  G  G PG PG PG ++G  GS  +      P   G KG PGL G+ G  G+ G+ 
Sbjct: 1080 EKGEKGSIGIPGMPGSPG-LKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLP 1138

Query: 202  GDPG------HQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMV 255
            G PG       +G+PG  G  G++GE+G PG PG +G  G+PG  G KG  G  G+ G+ 
Sbjct: 1139 GTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPG-RGFPGFPGAKGDKGSKGEVGFPGLA 1197

Query: 256  GAIGATGPPGEEGPRGPPGRAGEKGDEGSPG--IRGPQGITGPKGATGPPGINGKDGTPG 313
            G+ G  G  GE+G  GPPG  G+ G  GSPG    GP+G  GP+G  G PG+ G  G PG
Sbjct: 1198 GSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPG 1257

Query: 314  TPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPG 373
             PG+ G  G  G PG PG  G+ G  G PG +G PG  G PG  G  G  GPPG  G  G
Sbjct: 1258 LPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQG 1317

Query: 374  PRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKG-EQGPPGIPGPQGLPGVKGDKGSP 432
            P+G  G QGI G +GDQG  G  G PGP G  GP    +G PG+PGP+G PG+KG +G P
Sbjct: 1318 PKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLP 1377

Query: 433  GKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYP 492
               GP+G+ G  G+ G+PG  G  G  G PG KG+          GP+G  G  G   +P
Sbjct: 1378 ---GPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEM---------GPAGPTGPRG---FP 1422

Query: 493  GPPGPRGLAGNRGVPGQP 510
            GPPGP GL G+ G PG P
Sbjct: 1423 GPPGPDGLPGSMGPPGTP 1440



 Score =  372 bits (956), Expect = e-103
 Identities = 242/623 (38%), Positives = 281/623 (45%), Gaps = 130/623 (20%)

Query: 165 GLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGI 224
           G  GS    C  +   G KG  GL G++G  G  G+ G  G QG PG KGD G  G  G 
Sbjct: 30  GCAGSGCGKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGT 89

Query: 225 PGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPG---------- 274
            G  GP G  GYPG  G  G  G  G  G  G  G  G  GE GP GPPG          
Sbjct: 90  KGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGP 149

Query: 275 ---------------------RAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPG 313
                                  GE+G  G PG  GP G+ G +G  GPPG  G  G PG
Sbjct: 150 PGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPG 209

Query: 314 TPGMKGSAGQ-----AGQPGSPGHQGLAGVPGQPG-----------TKGGPGDQGEPGPQ 357
            PG  G  GQ      G  G  G QG++G PG PG           TKG  G +GEPG Q
Sbjct: 210 PPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQ 269

Query: 358 GLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIP 417
           G+PG  G  G+ G+PGPRG+ G  G  G+KG  G  G  G PG  GRQGP+GE+G  G P
Sbjct: 270 GMPGV-GEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPP 328

Query: 418 GPQGLP------GVKGDKGSPGKTGPRGKVGDPGVAGLPGE--------KGEKGESGEPG 463
           GP G+       G KG++G PG  GPRG+ G  G  GLPG+         G+ G  G PG
Sbjct: 329 GPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPG 388

Query: 464 PKGQQGVRGEPG--YPGPSGDAGAPGVQGYPGPPGPRGLAGN--RGVPGQPGRQGVEGRD 519
            +G++G RG PG   PGPSG  G PG  G PGPPG  G         PG PG QG  G  
Sbjct: 389 ERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIP 448

Query: 520 ATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPP--------------- 564
                I ++  K    Q  E  +    +     G  GPPGP GPP               
Sbjct: 449 GQPGFIGEIGEK---GQKGESCLICDID-----GYRGPPGPQGPPGEIGFPGQPGAKGDR 500

Query: 565 GYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGP-------KGKRGEKGDPGEVGR------ 611
           G PG+ G  G PGP+G PG++G  G  G  G        KG +G+ G PG+ G       
Sbjct: 501 GLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGS 560

Query: 612 ----GHPGMPGPPGIPGL------------------------PGRPGQAINGKDGDRGSP 643
               GHPG+PGP G PG                         PG PG    G  GD+G  
Sbjct: 561 PGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQA 620

Query: 644 GAPGEAGRPGLPGPVGLPGFCEP 666
           G PG  G PGLPGP G PG   P
Sbjct: 621 GFPGGPGSPGLPGPKGEPGKIVP 643



 Score =  342 bits (876), Expect = 9e-94
 Identities = 205/436 (47%), Positives = 229/436 (52%), Gaps = 50/436 (11%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
            G PGE+G PG PGP G PG  G  G  G  G+AGPPG  G PG  G  G  G  G  G  
Sbjct: 1020 GTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGI-GIPGLRGEKGDQGIAGFPGSP 1078

Query: 87   GAKGEPGPMGIPGVKGQPGLPGPPGLPG-PGFAGPPGPPGPVGLPGEIGIRGPKGDPGPD 145
            G KGE G +GIPG+ G PGL G PG  G PG  G PG  G  GLPG  GI G KG+ G  
Sbjct: 1079 GEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLP 1138

Query: 146  GPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGM--KGPPGLQGVKGHAGKRGILGD 203
            G  GP GP G+ G PG+  G+ GSA         PG+  +G PG  G KG  G +G +G 
Sbjct: 1139 GTPGPTGPAGQKGEPGS-DGIPGSAG----EKGEPGLPGRGFPGFPGAKGDKGSKGEVGF 1193

Query: 204  PGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGP 263
            PG  G PG  G   + GEQG  GPPGPQG  G PG  G   E GP G +G  G  G  G 
Sbjct: 1194 PGLAGSPGIPG---SKGEQGFMGPPGPQGQPGLPGSPGHATE-GPKGDRGPQGQPGLPGL 1249

Query: 264  PGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQ 323
            PG  GP G PG  G KGD+G+PG  G  G+ GPKG    PG  G  G  G+PG+ GS G 
Sbjct: 1250 PGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKG---DPGFQGMPGIGGSPGITGSKGD 1306

Query: 324  AGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGK----EGEPGPRGEIG 379
             G PG PG QG  G+PG  G KG  GDQG PG +GLPG  GPPG     +GEPG  G  G
Sbjct: 1307 MGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEG 1366

Query: 380  P------QGIMGQKGDQG------------------------ERGPVGQPGPQGRQGPKG 409
            P      QG+ G KG QG                        E GP G  GP+G  GP G
Sbjct: 1367 PPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPG 1426

Query: 410  EQGPPGIPGPQGLPGV 425
              G PG  GP G P V
Sbjct: 1427 PDGLPGSMGPPGTPSV 1442



 Score =  289 bits (740), Expect = 5e-78
 Identities = 169/387 (43%), Positives = 198/387 (51%), Gaps = 40/387 (10%)

Query: 22   LAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPG 81
            +A   G PGE+G  G  G PG+PGS G+ G  G  G  G PG  GE G  G  G DG PG
Sbjct: 1071 IAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPG 1130

Query: 82   IDGLTGAKGEPGPMGIPGVKGQPG---LPGP------PGLPGPGFAGPPGPPGPVGLPGE 132
            + G  G  G PGP G  G KG+PG   +PG       PGLPG GF G PG  G  G  GE
Sbjct: 1131 VKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGE 1190

Query: 133  IGIRGPKGDPGPDGPSG------PPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPP 186
            +G  G  G PG  G  G      PPGP G+PG PG+            P +   G KG  
Sbjct: 1191 VGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGS------------PGHATEGPKGDR 1238

Query: 187  GLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGET 246
            G QG  G  G  G +G PG  G  G KGD G  G  G PG PGP+G  G+ GM G  G  
Sbjct: 1239 GPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSP 1298

Query: 247  GPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGP---- 302
            G  G K   G +G  G PG +GP+G PG  G KGD+G  G+ G +G+ GP G  GP    
Sbjct: 1299 GITGSK---GDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDII 1355

Query: 303  ---PGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGE---PGP 356
               PG+ G +G PG  G++G  G  GQ G  G  G+ G PG PG  G PG +GE    GP
Sbjct: 1356 KGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGP 1415

Query: 357  QGLPGFSGPPGKEGEPGPRGEIGPQGI 383
             G  GF GPPG +G PG  G  G   +
Sbjct: 1416 TGPRGFPGPPGPDGLPGSMGPPGTPSV 1442



 Score =  138 bits (348), Expect = 1e-32
 Identities = 90/233 (38%), Positives = 101/233 (43%), Gaps = 76/233 (32%)

Query: 27   GPPGERGP---------PGPPGPPGVPGSDGIDGDNGPPG---KAGPPGPKGEPGKAGPD 74
            GP G+RGP         PGP GPPG+PG DG+ GD G PG     G PGPKG+PG  G  
Sbjct: 1233 GPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMP 1292

Query: 75   GPDGKPGIDG---------------------LTGAKGEPGPMGIPGVKGQPGLPGPPG-- 111
            G  G PGI G                     L G KG+ G  G+PG KG PG PGPPG  
Sbjct: 1293 GIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPY 1352

Query: 112  --------LPGP-------GFAGPPGP------------PGPVGLPG------------E 132
                    LPGP       G  G PGP            PGP G+PG             
Sbjct: 1353 DIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGP 1412

Query: 133  IGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQG--LEGSADFLCPTNCPPGMK 183
             G  GP+G PGP GP G PG  G PG P    G  +   +  +    CP G K
Sbjct: 1413 AGPTGPRGFPGPPGPDGLPGSMGPPGTPSVDHGFLVTRHSQTIDDPQCPSGTK 1465



 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 28/59 (47%), Positives = 30/59 (50%)

Query: 25   IRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGID 83
            + G  G  GPPG PG  G PG  G  G  GP G  G PGP G  G  G  GP G P +D
Sbjct: 1385 VTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSVD 1443


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score =  518 bits (1333), Expect = e-147
 Identities = 315/732 (43%), Positives = 369/732 (50%), Gaps = 88/732 (12%)

Query: 26   RGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGL 85
            +G PG  GP GPPGP G  G  G +G+ G  G  GPPG +G PG  G  G DG+ G+ G 
Sbjct: 360  KGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGP 419

Query: 86   TGAKGEPGPMGIPGVKG------QPGLPGPPGLPG-PGFAGPPGPPGPVGLPG------E 132
             G++G  GP G+ G  G      +PGL GP GLPG PG  GP G  GPVGLPG       
Sbjct: 420  PGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGP 479

Query: 133  IGIRGPKGDPGPDGPSGPPGPPGKPGRPGTI--QGLEGSADFLCPTNCPPGMKGPPGLQG 190
            IG  G +G+PG  G  GP GP G PG+ G     GL G+     P     G +GPPG QG
Sbjct: 480  IGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDG-NNGAQGPPGPQG 538

Query: 191  VKGHAGKRGILGDPGHQGKPGPKGDVGA---------SGEQGIPGPPGPQGIRGYPGMAG 241
            V+G  G++G  G PG QG PGP G  G           GE G+PGP GP+G RG PG +G
Sbjct: 539  VQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESG 598

Query: 242  PKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATG 301
              G TGP G +G  G  G  G  GE G  G  G AG  G  G PG RG  GI G KG  G
Sbjct: 599  AAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKG 658

Query: 302  PPGING------KDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPG 355
             PG+ G      +DG  G PG  G+ G AG  G  G  G AG  G  G +G PG++GE G
Sbjct: 659  EPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVG 718

Query: 356  PQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGE----- 410
            P G  GF+GP G  G+PG +GE G +G  G+ G  G  GPVG  GP G  GP G      
Sbjct: 719  PAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRG 778

Query: 411  -------------------------QGPPGIPGP---QGLPGVKGDKGSPGKTGPRGKVG 442
                                      GPPG PGP   +GL G +GD+G  G+TG  G VG
Sbjct: 779  DGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVG 838

Query: 443  DPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGY---PGPSGDAGAPGVQGYPGPPGPRG 499
             PG AG  G  GE G +G PG  G QG+ G PG    PG  G+ G PGV G  G PGP G
Sbjct: 839  PPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLG 898

Query: 500  LAGN---RGVPG---QPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVG 553
            +AG    RG PG    PG  G  G    D +  +        Q            +G VG
Sbjct: 899  IAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVG 958

Query: 554  MMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-RG 612
              G PGP GP G  GK G  G  GP G  G  GAVG  G +GP+G RG+KG+PGE G RG
Sbjct: 959  AAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRG 1018

Query: 613  HPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGP---------VGLPGF 663
             PG+ G  G+ GLPG     I G  GD+G+PG+ G AG  G  GP          G PG 
Sbjct: 1019 LPGLKGHNGLQGLPG-----IAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGT 1073

Query: 664  CEPAACLGASAY 675
              PA   G   +
Sbjct: 1074 VGPAGIRGPQGH 1085



 Score =  501 bits (1291), Expect = e-142
 Identities = 306/705 (43%), Positives = 354/705 (50%), Gaps = 96/705 (13%)

Query: 27  GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
           GP G  GPPG PG PG  G  G  G+ GP G AGP G  G PG +GP GP G PG +GLT
Sbjct: 247 GPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLT 306

Query: 87  GAKGEPGPMGIPGVKGQPGLPGPPGLPGP-GFAGPPGPPGPVGLPGEIGIRGP---KGDP 142
           GAKG  G   +PGV G PGLPGP G+PGP G AG  G  G VG PG  G +G    KG+P
Sbjct: 307 GAKGAAG---LPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEP 363

Query: 143 GPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILG 202
           G  GP GPPGP G+ G+ G               N   G  GPPG  G++G  G RG+ G
Sbjct: 364 GSAGPQGPPGPSGEEGKRGP--------------NGEAGSAGPPGPPGLRGSPGSRGLPG 409

Query: 203 DPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATG 262
             G  G  GP G  GASG  G+ GP G  G  G PG+ GP+G  G  G  G  G  G  G
Sbjct: 410 ADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVG 469

Query: 263 PPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAG 322
            PG +G  GP G AG +G+ G+ G        GPKG TG PG NG  G  G  G +G+  
Sbjct: 470 LPGIDGRPGPIGPAGARGEPGNIGF------PGPKGPTGDPGKNGDKGHAGLAGARGA-- 521

Query: 323 QAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGP---QGLPGFSGPPGKEGEPGPRGEIG 379
               PG  G+ G  G PG  G +GG G+QG PGP   QGLPG SGP G+ G+PG RG  G
Sbjct: 522 ----PGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHG 577

Query: 380 PQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRG 439
             G+ G  G +GERGP G+ G  G  GP G +GP G PGP G      +KG PG  G  G
Sbjct: 578 EFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDG------NKGEPGVVGAVG 631

Query: 440 KVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGP----- 494
             G  G +GLPGE+G  G  G  G KG+ G+RGE G PG  G  GAPG  G PGP     
Sbjct: 632 TAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATG 691

Query: 495 -------PGPRGLAGNRGVPGQPGRQGVEGRD-------ATDQHIV--DVALKMLQEQLA 538
                   GP G AG RG PG+ G  G  G +       A  Q     +   K  + +  
Sbjct: 692 DRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENG 751

Query: 539 EVAVSAKREALGAVGMMGPPGP------------------------------PGPPGYPG 568
            V  +    A G  G  GPPGP                               GPPG PG
Sbjct: 752 VVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPG 811

Query: 569 KQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-RGHPGMPGPPGIPGLPG 627
             G  G  GPRG  G VG  G++G  GP G  GEKG  GE G  G PG PGP G+ G PG
Sbjct: 812 PAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPG 871

Query: 628 RPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGA 672
             G  + G  G+RG PG  G  G PG  G  G PG   P   +G+
Sbjct: 872 ILG--LPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGS 914



 Score =  501 bits (1289), Expect = e-141
 Identities = 293/693 (42%), Positives = 343/693 (49%), Gaps = 69/693 (9%)

Query: 9   RSLLVLLQVVVLALAQI-------RGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGP 61
           R+LL+L   + LA  Q        +GP G+RGP G  GPPG PG DG DG  GPPG  GP
Sbjct: 8   RTLLLLAVTLCLATCQSLQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGP 67

Query: 62  PGPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPP 121
           PGP G  G       DGK       G    PGPMG+ G +G PG  G PG    GF GP 
Sbjct: 68  PGPPGLGGNFAAQY-DGK-------GVGLGPGPMGLMGPRGPPGAAGAPG--PQGFQGPA 117

Query: 122 GPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPG 181
           G PG  G  G  G RGP G PG  G  G PG PG+PG  G + G +G+  F       PG
Sbjct: 118 GEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVV-GPQGARGF-------PG 169

Query: 182 MKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAG 241
             G PG +G++GH G  G+ G PG    PG KG+ GA GE G PG  G +G+ G  G  G
Sbjct: 170 TPGLPGFKGIRGHNGLDGLKGQPG---APGVKGEPGAPGENGTPGQTGARGLPGERGRVG 226

Query: 242 PKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATG 301
             G  G  G  G VG +G  GP G  GP G PG  G KG+ G+ G  GP G  GP+G  G
Sbjct: 227 APGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVG 286

Query: 302 PPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPG 361
            PG++G  G PG PG  G  G          +G AG+PG  G  G PG +G PGP G  G
Sbjct: 287 LPGLSGPVGPPGNPGANGLTGA---------KGAAGLPGVAGAPGLPGPRGIPGPVGAAG 337

Query: 362 FSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQG 421
            +G  G  GEPGP G  G  G  G+ G  G +GP G  G +G++GP GE G  G PGP G
Sbjct: 338 ATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPG 397

Query: 422 LPGVKGDKGSPGKTGPRGKVGDPGV------AGLPGEKGEKGESGEPGPKGQQGVRGEPG 475
           L G  G +G PG  G  G +G PG       AG+ G  G+ G  GEPG  G +G+ G PG
Sbjct: 398 LRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPG 457

Query: 476 YPGPSGD---AGAPGVQGYPGPPGP---RGLAGNRGVPGQPGRQGVEGRDATDQHIVDVA 529
             GP+G     G PG+ G PGP GP   RG  GN G PG  G  G  G++    H     
Sbjct: 458 NIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAG 517

Query: 530 LKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVG 589
            +                  G  G  G  GPPGPPG+ G  GP G  G  G PG  G  G
Sbjct: 518 ARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHG 577

Query: 590 QIGNTGPKGKRGEKGDPGEVGRGHP-------GMPGPPGIPGLPGRPG------------ 630
           + G  GP G RGE+G PGE G   P       G  GPPG  G  G PG            
Sbjct: 578 EFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSG 637

Query: 631 -QAINGKDGDRGSPGAPGEAGRPGLPGPVGLPG 662
              + G+ G  G PG  GE G PGL G +G PG
Sbjct: 638 PSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPG 670



 Score =  411 bits (1056), Expect = e-114
 Identities = 256/628 (40%), Positives = 295/628 (46%), Gaps = 119/628 (18%)

Query: 27   GPPGERGPPGPPGPPG---------------VPGSDGIDGDNGPPGK---AGPPGPKGEP 68
            GPPG +G PGP GP G               +PG  G  G+ GPPG+   AGP GP G  
Sbjct: 550  GPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSR 609

Query: 69   GKAGPDGPDG---KPGIDGLTGAKGEPGPMGIPGVKGQPGLPG------PPGLPG----P 115
            G +GP GPDG   +PG+ G  G  G  GP G+PG +G  G+PG       PGL G    P
Sbjct: 610  GPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNP 669

Query: 116  GFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCP 175
            G  G  G PG VG PG  G  G +G+ G  GP+GP GP G PG  G + G  G   F  P
Sbjct: 670  GRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEV-GPAGPNGFAGP 728

Query: 176  TNCPP--------GMKGPPGLQGVKGHAGKRGILGDPGHQGKPGP---KGDVGASGEQGI 224
                         G KGP G  GV G  G  G  G  G  G PGP   +GD G  G  G 
Sbjct: 729  AGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGF 788

Query: 225  PG------PPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGE 278
            PG      PPGP GI G PG  GP G+ G  G +G  G +G TG   E G  GPPG AGE
Sbjct: 789  PGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTG---EVGAVGPPGFAGE 845

Query: 279  KGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGV 338
            KG  G  G  GP G  GP+G  G PGI G  G+ G  G+ G AG  G+PG  G  G  G 
Sbjct: 846  KGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGA 905

Query: 339  PGQPGTKGGPGDQGEPGPQGL---PGFSGPPGKEGEPGPRGE------IGPQGIMGQKGD 389
             G PG  G PG  G PG  G    PG  GPPG++G+PG +GE      IGP G  G  G 
Sbjct: 906  RGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGP 965

Query: 390  QGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPG---VKGDKGSPGKTGPR---GKVGD 443
             G  GP G+ G +G  GP G  GP G  GP+G  G   ++GDKG PG+ GPR   G  G 
Sbjct: 966  HGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGH 1025

Query: 444  PGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGN 503
             G+ GLPG  G  G+ G PG  G  G RG  G  GP+G  G  G  G  GP G RG  G+
Sbjct: 1026 NGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGH 1085

Query: 504  RGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGP 563
            +G  G PG                                             PPGPPGP
Sbjct: 1086 QGPAGPPG---------------------------------------------PPGPPGP 1100

Query: 564  PGYPGKQGPHGHPG-------PRGVPGI 584
            PG  G     G+ G       PR  P +
Sbjct: 1101 PGVSGGGYDFGYDGDFYRADQPRSAPSL 1128



 Score =  410 bits (1053), Expect = e-114
 Identities = 247/566 (43%), Positives = 280/566 (49%), Gaps = 57/566 (10%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPG------KAGPDGPDGKP 80
            GP G RG  GPPG  G  G  G  G  GP G  GP G KGEPG       AGP GP G P
Sbjct: 583  GPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLP 642

Query: 81   G------IDGLTGAKGEPG---PMGIPGVKGQPGLPGPPGLPGP----------GFAGPP 121
            G      I G  G KGEPG    +G PG  G  G PG  G PGP          G AGP 
Sbjct: 643  GERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPA 702

Query: 122  GPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPG 181
            GP GP G PGE G  GP G  G  GP+G  G PG  G  G  +G +G    + PT  P G
Sbjct: 703  GPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGA-KGPKGENGVVGPTG-PVG 760

Query: 182  MKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAG 241
              GP G  G  G AG RG  G PG  G PG  G  G  G  GI GPPGP G  G  G+ G
Sbjct: 761  AAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRG 820

Query: 242  PKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITG---PKG 298
            P+G+ GP G  G VGA+G  G  GE+GP G  G AG  G  G  G+ G  GI G    +G
Sbjct: 821  PRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRG 880

Query: 299  ATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQG 358
              G PG+ G  G PG  G+ G  G  G PG+ G  G+ G PG+ G  G PG+ G PG  G
Sbjct: 881  ERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDG 940

Query: 359  LPGFSG---------PPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPG------PQG 403
             PG  G         P G  G PGP G +GP G  G +G+ G  GPVG  G      P G
Sbjct: 941  QPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSG 1000

Query: 404  RQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPG 463
             QG +G++G PG  GP+GLPG+KG  G  G  G  G  GD G  G  G  G +G +G  G
Sbjct: 1001 PQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSG 1060

Query: 464  PKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEG------ 517
            P G+ G  G PG  GP+G  G  G QG  GPPGP G  G  GV G     G +G      
Sbjct: 1061 PAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSGGGYDFGYDGDFYRAD 1120

Query: 518  --RDATD----QHIVDVALKMLQEQL 537
              R A       + VD  LK L  Q+
Sbjct: 1121 QPRSAPSLRPKDYEVDATLKSLNNQI 1146



 Score =  351 bits (901), Expect = 1e-96
 Identities = 217/515 (42%), Positives = 248/515 (48%), Gaps = 63/515 (12%)

Query: 179 PPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGE-QGI---PGPPGPQGIR 234
           P G +GPPG  G  G  G  G  G PG  G PG  G+  A  + +G+   PGP G  G R
Sbjct: 40  PRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPR 99

Query: 235 GYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGIT 294
           G PG AG  G  G  G  G  G  G TGP G  GP GPPG+AGE G  G PG  G +G+ 
Sbjct: 100 GPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVV 159

Query: 295 GPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEP 354
           GP+GA G PG      TPG PG KG  G  G  G  G  G  GV G+PG    PG+ G P
Sbjct: 160 GPQGARGFPG------TPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGA---PGENGTP 210

Query: 355 GPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPP 414
           G  G  G  G  G+ G PGP G  G  G +G  G  G  G  G PG  G  GPKGE G  
Sbjct: 211 GQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAV 270

Query: 415 GIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEP 474
           G  GP G  G +G+ G PG +GP G  G+PG  GL G KG  G  G  G  G  G RG P
Sbjct: 271 GNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIP 330

Query: 475 GYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQ 534
           G  G +G  GA G+ G PGP G +G +GN+G PG  G QG  G    +            
Sbjct: 331 GPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEE------------ 378

Query: 535 EQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNT 594
                     KR   G  G  GPPGPPG  G PG +G    PG  G  G++G  G  G +
Sbjct: 379 ---------GKRGPNGEAGSAGPPGPPGLRGSPGSRGL---PGADGRAGVMGPPGSRGAS 426

Query: 595 GPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGL 654
           GP G RG  GD G  G   PG+ GP G+PG PG  G A              G+ G  GL
Sbjct: 427 GPAGVRGPNGDAGRPGE--PGLMGPRGLPGSPGNIGPA--------------GKEGPVGL 470

Query: 655 PGPVGLPGFCEPAACLGASAYASARLTEPGSIKGP 689
           PG  G PG   PA   G          EPG+I  P
Sbjct: 471 PGIDGRPGPIGPAGARG----------EPGNIGFP 495



 Score =  299 bits (765), Expect = 7e-81
 Identities = 185/453 (40%), Positives = 210/453 (46%), Gaps = 70/453 (15%)

Query: 256 GAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGK------- 308
           G  G  GP GE GP GPPGR GE G  G P         GP G  GPPG+ G        
Sbjct: 33  GPAGDRGPRGERGPPGPPGRDGEDGPTGPP---------GPPGPPGPPGLGGNFAAQYDG 83

Query: 309 ------DGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGF 362
                  G  G  G +G  G AG PG  G QG AG PG+PG  G  G +G  GP G  G 
Sbjct: 84  KGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGE 143

Query: 363 SGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGL 422
            G PGK G PG RG +GPQ   G +G  G  G  G  G +G  G  G +G PG PG +G 
Sbjct: 144 DGHPGKPGRPGERGVVGPQ---GARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGE 200

Query: 423 PGVKGDKGSPGKTGPRG------KVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGY 476
           PG  G+ G+PG+TG RG      +VG PG AG  G  G  G  G  GP G  G  G PG 
Sbjct: 201 PGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGA 260

Query: 477 PGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQ 536
           PGP G+ GA G  G  GP GPRG  G  G+ G  G  G  G                   
Sbjct: 261 PGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPG------------------- 301

Query: 537 LAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGP 596
                      A G  G  G  G PG  G PG  GP G PGP G  G  GA G +G  GP
Sbjct: 302 -----------ANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGP 350

Query: 597 KGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPG 656
            G +GE G+ GE     PG  GP G PG  G  G+   G +G+ GS G PG  G  G PG
Sbjct: 351 AGSKGESGNKGE-----PGSAGPQGPPGPSGEEGK--RGPNGEAGSAGPPGPPGLRGSPG 403

Query: 657 PVGLPGFCEPAACLGASAYASARLTEPGSIKGP 689
             GLPG    A  +G      A  + P  ++GP
Sbjct: 404 SRGLPGADGRAGVMGPPGSRGA--SGPAGVRGP 434



 Score =  259 bits (661), Expect = 8e-69
 Identities = 162/397 (40%), Positives = 184/397 (46%), Gaps = 79/397 (19%)

Query: 288 RGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGG 347
           +GP G  GP+G  GPPG  G+DG  G        G  G PG PG  GL G         G
Sbjct: 32  KGPAGDRGPRGERGPPGPPGRDGEDGP------TGPPGPPGPPGPPGLGG--NFAAQYDG 83

Query: 348 PGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGP 407
            G    PGP GL G  GPPG  G PGP               QG +GP G+PG  G+ GP
Sbjct: 84  KGVGLGPGPMGLMGPRGPPGAAGAPGP---------------QGFQGPAGEPGEPGQTGP 128

Query: 408 KGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQ 467
            G +GP G   P G  G  G  G PG+ G RG VG  G  G PG  G  G  G  G  G 
Sbjct: 129 AGARGPAG---PPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGL 185

Query: 468 QGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVD 527
            G++G+PG PG  G+ GAPG  G PG  G RGL G RG  G PG  G  G D +      
Sbjct: 186 DGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGS------ 239

Query: 528 VALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGA 587
                                +G VG  GP G  GPPG+PG  GP G          +GA
Sbjct: 240 ---------------------VGPVGPAGPIGSAGPPGFPGAPGPKGE---------IGA 269

Query: 588 VGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPG 647
           VG  G  GP G RGE G         PG+ GP G PG PG      NG  G +G+ G PG
Sbjct: 270 VGNAGPAGPAGPRGEVG--------LPGLSGPVGPPGNPGA-----NGLTGAKGAAGLPG 316

Query: 648 EAGRPGLPGPVGLPGFCEPAACLGASAYASARLTEPG 684
            AG PGLPGP G+PG   P    GA+  A   + EPG
Sbjct: 317 VAGAPGLPGPRGIPG---PVGAAGATG-ARGLVGEPG 349



 Score =  201 bits (511), Expect = 2e-51
 Identities = 123/271 (45%), Positives = 140/271 (51%), Gaps = 25/271 (9%)

Query: 19   VLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDG 78
            +L    I G PG RG  G PG  G  G  G  G  GPPG  GPPG  G P   G +G  G
Sbjct: 866  LLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSP---GVNGAPG 922

Query: 79   KPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGP 138
            + G DG  G  G PG  G PG KG+ G PG  G    G AG PGP GPVG  G+ G RG 
Sbjct: 923  EAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIG--PVGAAGAPGPHGPVGPAGKHGNRGE 980

Query: 139  KGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKR 198
             G  GP GP+G  GP G P  P  I+G +G           PG KGP GL G+KGH G +
Sbjct: 981  TGPSGPVGPAGAVGPRG-PSGPQGIRGDKGE----------PGEKGPRGLPGLKGHNGLQ 1029

Query: 199  GILGDPGHQGKPGPKGDVGASGEQGIPGPPGP---QGIRGYPGMAGPKGETGPHGYKGMV 255
            G+ G  GH G  G  G VG +G +G  GP GP    G  G+PG  GP G  GP G++   
Sbjct: 1030 GLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQ--- 1086

Query: 256  GAIGATGPPGEEGPRGPPGRAGEKGDEGSPG 286
               G  GPPG  GP GPPG +G   D G  G
Sbjct: 1087 ---GPAGPPGPPGPPGPPGVSGGGYDFGYDG 1114



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 19/30 (63%), Positives = 20/30 (66%), Gaps = 3/30 (10%)

Query: 26   RGPPGERGPPGPPGPPGVPGSD---GIDGD 52
            +GP G  GPPGPPGPPGV G     G DGD
Sbjct: 1086 QGPAGPPGPPGPPGPPGVSGGGYDFGYDGD 1115


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score =  516 bits (1330), Expect = e-146
 Identities = 306/714 (42%), Positives = 352/714 (49%), Gaps = 70/714 (9%)

Query: 20   LALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGK 79
            L +  + G PG +GP G  G PG PG+ G  G  G  GK+GP G +G  G  G  GP G 
Sbjct: 709  LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 768

Query: 80   PGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPK 139
             G  G  G  G  GP G PG +G PG  GP G PGP   GPPGPPG  GLPG  G RG  
Sbjct: 769  TGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP--KGPPGPPGKDGLPGHPGQRGEV 826

Query: 140  GDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRG 199
            G  G  GP GPPG  G  G  G   G  G           PG  GPPG QG+ G AGK G
Sbjct: 827  GFQGKTGPPGPPGVVGPQGAAGET-GPMGERGH-------PGPPGPPGEQGLPGTAGKEG 878

Query: 200  ILGDPGHQGKPG---PKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVG 256
              GDPG  G PG   P G  G  GE+G+PG  G  G++G  G +GP G  G  G +G  G
Sbjct: 879  TKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAG 938

Query: 257  AIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGP------QGITGPKGATGPPGINGKDG 310
            + G  GPPG  GP+GPPG AGEKG  G  G  GP      QG  G  G  GPPG+ G+DG
Sbjct: 939  SGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDG 998

Query: 311  TPGT---PGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPG 367
              G    PG KG+ G  G+ G PG  G  G  GQPG  G  G+ G  GPQG  G  G  G
Sbjct: 999  DKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEG 1058

Query: 368  KEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKG 427
              G  GP G IG QG+ G  G++GE G VG  GP G  GP+G  GP G  GPQG PG  G
Sbjct: 1059 TRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVG 1118

Query: 428  DKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGA-- 485
            + G PG+ G  G+ G PG+ G PG KG +GE GE G  GQ G  G PG  GP+GD G   
Sbjct: 1119 NLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKG 1178

Query: 486  -PGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSA 544
             PG  G+PG PGP G  G RG  G  G +G +G                  Q      + 
Sbjct: 1179 NPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG---------------QPGSPGPTG 1223

Query: 545  KREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKG 604
            +    G +G  GP G PG  G  G +G  G PG  G PG  G VG  G  G  G  G +G
Sbjct: 1224 ENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRG 1283

Query: 605  DPGEVGR-------GHPGMPGPPGIPGLPGRPGQA----------------INGKDGDRG 641
             PG VG+       G  G PGP G PGLPG  G A                  G+ G++G
Sbjct: 1284 LPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKG 1343

Query: 642  SPGAPGEAGRPGLPGPVGLPGFCEPAACLG-------ASAYASARLTEPGSIKG 688
              G PG  G PG  G +G+PG   P    G       A    +   T PG  KG
Sbjct: 1344 DRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKG 1397



 Score =  503 bits (1295), Expect = e-142
 Identities = 330/789 (41%), Positives = 380/789 (48%), Gaps = 122/789 (15%)

Query: 14   LLQVVVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNG---------PPGKAGPPGP 64
            +LQ   LAL   RGPPG  G  G PGP G PGS G+ G++G         P G  GPPG 
Sbjct: 391  ILQQARLAL---RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGK 447

Query: 65   KGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQ------PGLPGPPG------- 111
             G  G+AG DG  G PG  G+ G +G  G  G+PG KG        GLPGPPG       
Sbjct: 448  AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGD 507

Query: 112  --------LPGP----GFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGR 159
                    LPG     G  GP GPPG  G PG  G+ GP+G  G  GP G PGPPG+ G 
Sbjct: 508  DGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT 567

Query: 160  PGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGAS 219
            PGT QGL G    + P     G KGP G  G+ G  G  G  G PG +G PG KG+ G S
Sbjct: 568  PGT-QGLPGPQGAIGPH----GEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS 622

Query: 220  GEQGIPGPPGPQG------IRGYPGMAGPKGETGPHGYKGMVGA------IGATGPPGEE 267
            G QG  G PGP+G      IRG  G  G KGE G  G+KG +G       +G  G  GE+
Sbjct: 623  GPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED 682

Query: 268  GPRGPPGRAGEKGDEGSPGIRGPQGITG------------PKGATGPPG----------- 304
            GP GP GR G  GD G PG+ G +G  G            PKG+ G PG           
Sbjct: 683  GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGAR 742

Query: 305  -INGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFS 363
             ++GK G  G  G  G  GQ G  G+ G  G  G  G  G  G PG++G PGPQG  GF 
Sbjct: 743  GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 802

Query: 364  GP------PGKEG---EPGPRGEIG---------PQGIMGQKGDQGERGPVGQPGPQGRQ 405
            GP      PGK+G    PG RGE+G         P G++G +G  GE GP+G+ G  G  
Sbjct: 803  GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 862

Query: 406  GPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGE------KGEKGES 459
            GP GEQG PG  G +G  G  G  G+PGK GP G  G PG  GLPG       KG +G S
Sbjct: 863  GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPS 922

Query: 460  GEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRD 519
            G PGP G  G RG  G  GP G  G PG QG PG  G +G+ G +G  G  GR GV+G  
Sbjct: 923  GPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPV 982

Query: 520  ATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGP------------PGYP 567
                      +        EV    ++   G  G  GPPGPPGP             G P
Sbjct: 983  GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEP 1042

Query: 568  GKQGPHGH---PGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-RGHPGMPGPPGIP 623
            G +GP GH    G  G  G  G  G IG  G  G  GEKG+ G+VG  G PG PGP G  
Sbjct: 1043 GARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPA 1102

Query: 624  GLPGRPG-QAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASARLTE 682
            G  G  G Q   G  G+ G PG  GE G  G PG  G PG   P    G     S +  E
Sbjct: 1103 GPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG-ESGQPGE 1161

Query: 683  PG--SIKGP 689
            PG    KGP
Sbjct: 1162 PGPPGPKGP 1170



 Score =  492 bits (1267), Expect = e-139
 Identities = 306/713 (42%), Positives = 363/713 (50%), Gaps = 110/713 (15%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
            GP G+RGP G  G  G  G+ G DG +GPPG+ G PGP+G  G  GP GP G PG DGL 
Sbjct: 758  GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLP 817

Query: 87   GAKGEPGPMGIPGVKGQPGLPGPPGLPGP-------------GFAGPPGPPGPVGLPGEI 133
            G    PG  G  G +G+ G PGPPG+ GP             G  GPPGPPG  GLPG  
Sbjct: 818  G---HPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTA 874

Query: 134  GIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADF--LCPTNCPPGMKGPPGLQGV 191
            G  G KGDPGP G  G  GP G  G PG  +GL G+A    L     P G  GP G  G 
Sbjct: 875  GKEGTKGDPGPPGAPGKDGPAGLRGFPGE-RGLPGTAGGPGLKGNEGPSGPPGPAGSPGE 933

Query: 192  KGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGP---------QGIRGYPGMAGP 242
            +G AG  G +G PG   +PGP+G  GA+GE+G+PG  GP         QG  G PG AGP
Sbjct: 934  RGAAGSGGPIGPPG---RPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP 990

Query: 243  ---------KGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGI 293
                     KGE G  G KG  G  G  GPPG  GP GP G+ G  G +G PG RGPQG 
Sbjct: 991  PGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGH 1050

Query: 294  TGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGE 353
             G KG  G  G NG    PG  G++G  G +G+ G  G  G  G PG PG +G  G  G 
Sbjct: 1051 FGAKGDEGTRGFNGP---PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGA 1107

Query: 354  PGPQGLPGFSG---PPGKEGEPGP------RGEIGPQGIMGQKGDQGERGPVGQPGPQGR 404
             GPQG PG  G   PPG++GEPG       +GE G +G  G++G++GE G  G+PGP G 
Sbjct: 1108 DGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGP 1167

Query: 405  QGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVG------DPGVAGLPGEKGEKGE 458
            +GP G+ GP G PGP G PG   D G PG+ GPRG+ G      + G  G PG  G  GE
Sbjct: 1168 KGPTGDDGPKGNPGPVGFPG---DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGE 1224

Query: 459  SGEPGPKGQQGVRGEPGYPG------PSGDAGAPGVQGYPGPPGPRGLAGN------RGV 506
            +G PGP G++G  G PG  G        GD GA G  G  GP GP G AG       RG+
Sbjct: 1225 NGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGL 1284

Query: 507  PGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGP------ 560
            PG  G+QG  G          V    L     +     ++   G +G++GPPG       
Sbjct: 1285 PGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGD 1344

Query: 561  ---PGPPGYPGKQGPHGHPG---------PRGVPGIVGAVGQIGNTGPKGKRGEKGDPGE 608
               PGP G PG++G  G PG         P G+PG  G  G  G TGP G +GEKG    
Sbjct: 1345 RGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKG---- 1400

Query: 609  VGRGHPGMPGPPG--IPGLP-GRPGQAINGKDGDR-----------GSPGAPG 647
              +G PG PGPPG  I  LP   P +     DG R           G+PG+PG
Sbjct: 1401 -VQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1452



 Score =  488 bits (1257), Expect = e-138
 Identities = 308/792 (38%), Positives = 358/792 (45%), Gaps = 174/792 (21%)

Query: 25   IRGPPGERGPPGPPGPPGV---PGSDGIDGDNGPPGKA---------------------- 59
            + GPPG  GP G  GPPG+   PG  G  G+ GPPG+A                      
Sbjct: 311  VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRF 370

Query: 60   ------------------------------GPPGPKGEPGKAGPDGPDGKPGIDGLTGAK 89
                                          GPPGP G  G+ GP G  G PG+ G +G  
Sbjct: 371  GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 430

Query: 90   GEPGPM---------------------------GIPGVKGQPGLPGPPGLPG-------- 114
            G  GP                            G PGVKG  G  G PGLPG        
Sbjct: 431  GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDT 490

Query: 115  --PGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADF 172
               G  GPPG  G  G  GEIG RG  G+ GP G  GP GPPG PG PG ++G++G    
Sbjct: 491  GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPG-VRGMDGPQG- 548

Query: 173  LCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQG 232
                  P G  GP G  G  G  G  G  G PG QG  GP G+ G  G+ G+PG PG  G
Sbjct: 549  ------PKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 602

Query: 233  IRGYPGMAGP---KGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRG 289
              G+PG  GP   KG  GP G +G +G  G  G  G +G RG  G  GEKG++G PG +G
Sbjct: 603  PPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKG 662

Query: 290  PQGITGPKGATGPPGINGKD------------GTPGTPGMKGSAGQAGQPGSPGHQGLAG 337
              G+ G +G  G PG  G+D            G PG PG+ G  G+ G PG PG+ G  G
Sbjct: 663  DIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQG 722

Query: 338  VPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQ------- 390
              G  G  G PG  GE G +GL G SGP G+ G  GPRG+ GP+G  G+ G +       
Sbjct: 723  PKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDG 782

Query: 391  -----GERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGK---VG 442
                 GERG  G  GP G  GPKG  GPPG  G  G PG +G+ G  GKTGP G    VG
Sbjct: 783  PHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVG 842

Query: 443  DPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAG 502
              G AG  G  GE+G  G PGP G+QG+ G  G  G  GD G PG  G  GP G RG  G
Sbjct: 843  PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG 902

Query: 503  NRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPG 562
             RG+PG  G  G++G +                         +R A G+ G +GPPG PG
Sbjct: 903  ERGLPGTAGGPGLKGNEGP------------SGPPGPAGSPGERGAAGSGGPIGPPGRPG 950

Query: 563  PPGYPGKQGPHGHP------GPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG------ 610
            P G PG  G  G P      GP G  G+ G VG  G  GP G  GE GD GEVG      
Sbjct: 951  PQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKG 1010

Query: 611  ----RGHPGMPGPPGIPGLPGRPGQA----------------INGKDGDRGSPGAPGEAG 650
                +G  G PGPPG  G  G+PG A                  G +G RG  G PG  G
Sbjct: 1011 TKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIG 1070

Query: 651  RPGLPGPVGLPG 662
              GLPGP G  G
Sbjct: 1071 LQGLPGPSGEKG 1082



 Score =  484 bits (1246), Expect = e-136
 Identities = 291/702 (41%), Positives = 353/702 (50%), Gaps = 82/702 (11%)

Query: 33  GPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT------ 86
           GPPGP GP G+ G  GI G+   PG  G PG +G PG+AG  G DG PG  G +      
Sbjct: 313 GPPGPEGPAGLIGPPGIQGN---PGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFR 369

Query: 87  --GAKGEPGPMGIPGVKGQP---------GLPGPPGLPG-PGFAGPPGPPGPVGLPGEIG 134
                G+ GP+ +   + Q           L GPPG  G  G  GP G PG  GL GE G
Sbjct: 370 FGSGGGDKGPV-VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESG 428

Query: 135 IRGPKGDPGPDGPSGPPGPPGKPGRPGT--IQGLEGSADFLCPTNCPPGMKGPPGLQGVK 192
             GP+G  GP G +GPPG  G+ GR G    +G+ G           PG+KG  G  G+ 
Sbjct: 429 DLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGD----------PGVKGDRGFDGLP 478

Query: 193 GHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYK 252
           G  G++G  GD G QG PGP G+ G  G+ G  GP G  G  G  G+ GPKG  G  G  
Sbjct: 479 GLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPP 538

Query: 253 GMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTP 312
           G+ G  G  GP G  GP+G PG  G++G  G+ G+ GPQG  GP G  GP G  G  G P
Sbjct: 539 GVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMP 598

Query: 313 GTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEP 372
           G+ G  G  G+ G PG+ G+QG +G  G  G  G  G +G  G +GL G  G  G++G P
Sbjct: 599 GSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFP 658

Query: 373 GPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSP 432
           G +G+IG +G  G+ G  G RG  G  GP+GR GP G+ GPPG+ G +G  GV G  G P
Sbjct: 659 GFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYP 718

Query: 433 GKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGP------------- 479
           G+ GP+G +G PG  G  GEKG +G SG+ GP+G++G  G  G  GP             
Sbjct: 719 GRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTS 778

Query: 480 --SGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQL 537
              G  G PG +G PGP GP G  G +G PG PG+ G+ G         +V  +      
Sbjct: 779 GGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRG---EVGFQGKTGPP 835

Query: 538 AEVAVSAKREALGAVGMM------GPPGP------------------PGPPGYPGKQGP- 572
               V   + A G  G M      GPPGP                  PGPPG PGK GP 
Sbjct: 836 GPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPA 895

Query: 573 --HGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMP-GPPGIPGLPGRP 629
              G PG RG+PG  G  G  GN GP G  G  G PGE G    G P GPPG PG  G P
Sbjct: 896 GLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPP 955

Query: 630 GQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLG 671
           G A  G+ G  G  G  G  GR G+ GPVGLPG   P    G
Sbjct: 956 GAA--GEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAG 995



 Score =  293 bits (751), Expect = 3e-79
 Identities = 192/497 (38%), Positives = 224/497 (45%), Gaps = 93/497 (18%)

Query: 263 PPGEEGPRGPPGRAGEKGDEG--SPG--IRGPQGITGPKGATGPPGINGKDGTPGTPGMK 318
           PP EE   GP G  GEKG+     PG  + GP G  GP G  GPPGI G  G  G PG +
Sbjct: 283 PPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGER 342

Query: 319 GSAGQAGQPGSPGHQG----------------------------------------LAGV 338
           G  G+AG PGS G  G                                        L G 
Sbjct: 343 GPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGP 402

Query: 339 PGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQ 398
           PG  G  G PG  G+PG  GL G SG  G +G  GP+G  GP G  G++G  G  G  G 
Sbjct: 403 PGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGM 462

Query: 399 PGPQGRQGPKGEQGPPGIP---------GPQGLPGVKGD------------KGSPGKTGP 437
           PG  G +G +G  G PG+P         G QGLPG  G+            +G PG++GP
Sbjct: 463 PGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGP 522

Query: 438 RGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGP 497
           RG +G  G  G+PG  G +G  G  GPKG  G +GE   PGP G  G PG QG PGP G 
Sbjct: 523 RGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGE---PGPPGQQGTPGTQGLPGPQGA 579

Query: 498 RGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGP 557
            G  G +G  G+PG  G+ G D    H                    K    G  G  GP
Sbjct: 580 IGPHGEKGPQGKPGLPGMPGSDGPPGH------------------PGKEGPPGTKGNQGP 621

Query: 558 PGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG----RGH 613
            GP GP GYPG +G  G  G RG+ G  G  G+ G  G KG  G KGD GEVG    RG 
Sbjct: 622 SGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGE 681

Query: 614 PGMPGPPGIPGLPGRPG-QAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGA 672
            G  GP G  G  G PG   + G+ G  G PG PG  GR G  G +G PGF  P A    
Sbjct: 682 DGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGF--PGASGEK 739

Query: 673 SAYASARLTEPGSIKGP 689
            A   +  + P   +GP
Sbjct: 740 GARGLSGKSGPRGERGP 756



 Score =  274 bits (701), Expect = 2e-73
 Identities = 157/350 (44%), Positives = 182/350 (52%), Gaps = 30/350 (8%)

Query: 26   RGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGL 85
            RGP G  G  GP GPPG  G+ G  G+ G PG++G PG +GEPG  GP G  G+    G 
Sbjct: 1099 RGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGE---KGE 1155

Query: 86   TGAKGEPGPMGIPGVKGQPGLPGPPGLPGP-GFAGPPGPPGPVGLPGEIGIRGPKGDPGP 144
            +G  GEPGP   PG KG  G  GP G PGP GF G PGPPG  G  G+ G +G +G+ G 
Sbjct: 1156 SGQPGEPGP---PGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGE 1212

Query: 145  DGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDP 204
             G  G PGP G+ G PG                 P G +GP G  G +G  G +G  GDP
Sbjct: 1213 PGQPGSPGPTGENGPPG-----------------PLGKRGPAGSPGSEGRQGGKGAKGDP 1255

Query: 205  GHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPP 264
            G  G PG  G VG +G     G PGP G+RG PG  G +G  G     G  G  G  GPP
Sbjct: 1256 GAIGAPGKTGPVGPAGP---AGKPGPDGLRGLPGSVGQQGRPGA---TGQAGPPGPVGPP 1309

Query: 265  GEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQA 324
            G  G RG  G  GEKG  G  G+ GP G  G KG  G PG  G  G  G  G+ G++G  
Sbjct: 1310 GLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPI 1369

Query: 325  GQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGP 374
            G  G PG  G AG  G  G  G  G +GE G QG PG  GPPG+  +P P
Sbjct: 1370 GPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1419



 Score =  132 bits (332), Expect = 1e-30
 Identities = 86/206 (41%), Positives = 98/206 (47%), Gaps = 44/206 (21%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGI---------------DGDNGPPGKAGPPG-------- 63
            G PG+ GP GP GP G PG DG+                G  GPPG  GPPG        
Sbjct: 1259 GAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDA 1318

Query: 64   ----PKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGF-A 118
                 KG PG  G  GP   PG  G  G +G PGP G PG KG+ G+PG  G  GPG   
Sbjct: 1319 GAKGEKGHPGLIGLIGP---PGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP 1375

Query: 119  GPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQ-------GLEGS-- 169
            G PGP GP G  G  G  GPKG+ G  GP G PGPPG+  +P  IQ        ++GS  
Sbjct: 1376 GLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRL 1435

Query: 170  --ADFLCPTNCPPGMKGPPGLQGVKG 193
               D   PT   PG   P GL+ + G
Sbjct: 1436 MQEDEAIPTGGAPG--SPGGLEEIFG 1459



 Score =  103 bits (258), Expect = 4e-22
 Identities = 66/174 (37%), Positives = 80/174 (45%), Gaps = 31/174 (17%)

Query: 27   GPPGERGPPGPPGPPGVPG------------------------SDGIDGDNGPPGKAGPP 62
            G  G+ GPPGP GPPG+PG                          G  GD G PG  G P
Sbjct: 1295 GATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSP 1354

Query: 63   GPKGE---PGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAG 119
            G KGE   PG +GP GP G PG+ G  G KG  G  G  G KG+ G+ GPPG PGP   G
Sbjct: 1355 GQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGP--PG 1412

Query: 120  PPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFL 173
                P P+ +P +            +  + P G  G PG PG ++ + GS D L
Sbjct: 1413 EVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTG--GAPGSPGGLEEIFGSLDSL 1464


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score =  516 bits (1330), Expect = e-146
 Identities = 306/714 (42%), Positives = 352/714 (49%), Gaps = 70/714 (9%)

Query: 20   LALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGK 79
            L +  + G PG +GP G  G PG PG+ G  G  G  GK+GP G +G  G  G  GP G 
Sbjct: 688  LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 747

Query: 80   PGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPK 139
             G  G  G  G  GP G PG +G PG  GP G PGP   GPPGPPG  GLPG  G RG  
Sbjct: 748  TGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP--KGPPGPPGKDGLPGHPGQRGEV 805

Query: 140  GDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRG 199
            G  G  GP GPPG  G  G  G   G  G           PG  GPPG QG+ G AGK G
Sbjct: 806  GFQGKTGPPGPPGVVGPQGAAGET-GPMGERGH-------PGPPGPPGEQGLPGTAGKEG 857

Query: 200  ILGDPGHQGKPG---PKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVG 256
              GDPG  G PG   P G  G  GE+G+PG  G  G++G  G +GP G  G  G +G  G
Sbjct: 858  TKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAG 917

Query: 257  AIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGP------QGITGPKGATGPPGINGKDG 310
            + G  GPPG  GP+GPPG AGEKG  G  G  GP      QG  G  G  GPPG+ G+DG
Sbjct: 918  SGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDG 977

Query: 311  TPGT---PGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPG 367
              G    PG KG+ G  G+ G PG  G  G  GQPG  G  G+ G  GPQG  G  G  G
Sbjct: 978  DKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEG 1037

Query: 368  KEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKG 427
              G  GP G IG QG+ G  G++GE G VG  GP G  GP+G  GP G  GPQG PG  G
Sbjct: 1038 TRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVG 1097

Query: 428  DKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGA-- 485
            + G PG+ G  G+ G PG+ G PG KG +GE GE G  GQ G  G PG  GP+GD G   
Sbjct: 1098 NLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKG 1157

Query: 486  -PGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSA 544
             PG  G+PG PGP G  G RG  G  G +G +G                  Q      + 
Sbjct: 1158 NPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG---------------QPGSPGPTG 1202

Query: 545  KREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKG 604
            +    G +G  GP G PG  G  G +G  G PG  G PG  G VG  G  G  G  G +G
Sbjct: 1203 ENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRG 1262

Query: 605  DPGEVGR-------GHPGMPGPPGIPGLPGRPGQA----------------INGKDGDRG 641
             PG VG+       G  G PGP G PGLPG  G A                  G+ G++G
Sbjct: 1263 LPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKG 1322

Query: 642  SPGAPGEAGRPGLPGPVGLPGFCEPAACLG-------ASAYASARLTEPGSIKG 688
              G PG  G PG  G +G+PG   P    G       A    +   T PG  KG
Sbjct: 1323 DRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKG 1376



 Score =  503 bits (1295), Expect = e-142
 Identities = 330/789 (41%), Positives = 380/789 (48%), Gaps = 122/789 (15%)

Query: 14   LLQVVVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNG---------PPGKAGPPGP 64
            +LQ   LAL   RGPPG  G  G PGP G PGS G+ G++G         P G  GPPG 
Sbjct: 370  ILQQARLAL---RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGK 426

Query: 65   KGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQ------PGLPGPPG------- 111
             G  G+AG DG  G PG  G+ G +G  G  G+PG KG        GLPGPPG       
Sbjct: 427  AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGD 486

Query: 112  --------LPGP----GFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGR 159
                    LPG     G  GP GPPG  G PG  G+ GP+G  G  GP G PGPPG+ G 
Sbjct: 487  DGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT 546

Query: 160  PGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGAS 219
            PGT QGL G    + P     G KGP G  G+ G  G  G  G PG +G PG KG+ G S
Sbjct: 547  PGT-QGLPGPQGAIGPH----GEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS 601

Query: 220  GEQGIPGPPGPQG------IRGYPGMAGPKGETGPHGYKGMVGA------IGATGPPGEE 267
            G QG  G PGP+G      IRG  G  G KGE G  G+KG +G       +G  G  GE+
Sbjct: 602  GPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED 661

Query: 268  GPRGPPGRAGEKGDEGSPGIRGPQGITG------------PKGATGPPG----------- 304
            GP GP GR G  GD G PG+ G +G  G            PKG+ G PG           
Sbjct: 662  GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGAR 721

Query: 305  -INGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFS 363
             ++GK G  G  G  G  GQ G  G+ G  G  G  G  G  G PG++G PGPQG  GF 
Sbjct: 722  GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 781

Query: 364  GP------PGKEG---EPGPRGEIG---------PQGIMGQKGDQGERGPVGQPGPQGRQ 405
            GP      PGK+G    PG RGE+G         P G++G +G  GE GP+G+ G  G  
Sbjct: 782  GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 841

Query: 406  GPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGE------KGEKGES 459
            GP GEQG PG  G +G  G  G  G+PGK GP G  G PG  GLPG       KG +G S
Sbjct: 842  GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPS 901

Query: 460  GEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRD 519
            G PGP G  G RG  G  GP G  G PG QG PG  G +G+ G +G  G  GR GV+G  
Sbjct: 902  GPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPV 961

Query: 520  ATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGP------------PGYP 567
                      +        EV    ++   G  G  GPPGPPGP             G P
Sbjct: 962  GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEP 1021

Query: 568  GKQGPHGH---PGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-RGHPGMPGPPGIP 623
            G +GP GH    G  G  G  G  G IG  G  G  GEKG+ G+VG  G PG PGP G  
Sbjct: 1022 GARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPA 1081

Query: 624  GLPGRPG-QAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASARLTE 682
            G  G  G Q   G  G+ G PG  GE G  G PG  G PG   P    G     S +  E
Sbjct: 1082 GPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG-ESGQPGE 1140

Query: 683  PG--SIKGP 689
            PG    KGP
Sbjct: 1141 PGPPGPKGP 1149



 Score =  492 bits (1267), Expect = e-139
 Identities = 306/713 (42%), Positives = 363/713 (50%), Gaps = 110/713 (15%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
            GP G+RGP G  G  G  G+ G DG +GPPG+ G PGP+G  G  GP GP G PG DGL 
Sbjct: 737  GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLP 796

Query: 87   GAKGEPGPMGIPGVKGQPGLPGPPGLPGP-------------GFAGPPGPPGPVGLPGEI 133
            G    PG  G  G +G+ G PGPPG+ GP             G  GPPGPPG  GLPG  
Sbjct: 797  G---HPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTA 853

Query: 134  GIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADF--LCPTNCPPGMKGPPGLQGV 191
            G  G KGDPGP G  G  GP G  G PG  +GL G+A    L     P G  GP G  G 
Sbjct: 854  GKEGTKGDPGPPGAPGKDGPAGLRGFPGE-RGLPGTAGGPGLKGNEGPSGPPGPAGSPGE 912

Query: 192  KGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGP---------QGIRGYPGMAGP 242
            +G AG  G +G PG   +PGP+G  GA+GE+G+PG  GP         QG  G PG AGP
Sbjct: 913  RGAAGSGGPIGPPG---RPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP 969

Query: 243  ---------KGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGI 293
                     KGE G  G KG  G  G  GPPG  GP GP G+ G  G +G PG RGPQG 
Sbjct: 970  PGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGH 1029

Query: 294  TGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGE 353
             G KG  G  G NG    PG  G++G  G +G+ G  G  G  G PG PG +G  G  G 
Sbjct: 1030 FGAKGDEGTRGFNGP---PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGA 1086

Query: 354  PGPQGLPGFSG---PPGKEGEPGP------RGEIGPQGIMGQKGDQGERGPVGQPGPQGR 404
             GPQG PG  G   PPG++GEPG       +GE G +G  G++G++GE G  G+PGP G 
Sbjct: 1087 DGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGP 1146

Query: 405  QGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVG------DPGVAGLPGEKGEKGE 458
            +GP G+ GP G PGP G PG   D G PG+ GPRG+ G      + G  G PG  G  GE
Sbjct: 1147 KGPTGDDGPKGNPGPVGFPG---DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGE 1203

Query: 459  SGEPGPKGQQGVRGEPGYPG------PSGDAGAPGVQGYPGPPGPRGLAGN------RGV 506
            +G PGP G++G  G PG  G        GD GA G  G  GP GP G AG       RG+
Sbjct: 1204 NGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGL 1263

Query: 507  PGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGP------ 560
            PG  G+QG  G          V    L     +     ++   G +G++GPPG       
Sbjct: 1264 PGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGD 1323

Query: 561  ---PGPPGYPGKQGPHGHPG---------PRGVPGIVGAVGQIGNTGPKGKRGEKGDPGE 608
               PGP G PG++G  G PG         P G+PG  G  G  G TGP G +GEKG    
Sbjct: 1324 RGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKG---- 1379

Query: 609  VGRGHPGMPGPPG--IPGLP-GRPGQAINGKDGDR-----------GSPGAPG 647
              +G PG PGPPG  I  LP   P +     DG R           G+PG+PG
Sbjct: 1380 -VQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1431



 Score =  488 bits (1257), Expect = e-138
 Identities = 308/792 (38%), Positives = 358/792 (45%), Gaps = 174/792 (21%)

Query: 25   IRGPPGERGPPGPPGPPGV---PGSDGIDGDNGPPGKA---------------------- 59
            + GPPG  GP G  GPPG+   PG  G  G+ GPPG+A                      
Sbjct: 290  VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRF 349

Query: 60   ------------------------------GPPGPKGEPGKAGPDGPDGKPGIDGLTGAK 89
                                          GPPGP G  G+ GP G  G PG+ G +G  
Sbjct: 350  GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 409

Query: 90   GEPGPM---------------------------GIPGVKGQPGLPGPPGLPG-------- 114
            G  GP                            G PGVKG  G  G PGLPG        
Sbjct: 410  GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDT 469

Query: 115  --PGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADF 172
               G  GPPG  G  G  GEIG RG  G+ GP G  GP GPPG PG PG ++G++G    
Sbjct: 470  GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPG-VRGMDGPQG- 527

Query: 173  LCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQG 232
                  P G  GP G  G  G  G  G  G PG QG  GP G+ G  G+ G+PG PG  G
Sbjct: 528  ------PKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 581

Query: 233  IRGYPGMAGP---KGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRG 289
              G+PG  GP   KG  GP G +G +G  G  G  G +G RG  G  GEKG++G PG +G
Sbjct: 582  PPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKG 641

Query: 290  PQGITGPKGATGPPGINGKD------------GTPGTPGMKGSAGQAGQPGSPGHQGLAG 337
              G+ G +G  G PG  G+D            G PG PG+ G  G+ G PG PG+ G  G
Sbjct: 642  DIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQG 701

Query: 338  VPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQ------- 390
              G  G  G PG  GE G +GL G SGP G+ G  GPRG+ GP+G  G+ G +       
Sbjct: 702  PKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDG 761

Query: 391  -----GERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGK---VG 442
                 GERG  G  GP G  GPKG  GPPG  G  G PG +G+ G  GKTGP G    VG
Sbjct: 762  PHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVG 821

Query: 443  DPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAG 502
              G AG  G  GE+G  G PGP G+QG+ G  G  G  GD G PG  G  GP G RG  G
Sbjct: 822  PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG 881

Query: 503  NRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPG 562
             RG+PG  G  G++G +                         +R A G+ G +GPPG PG
Sbjct: 882  ERGLPGTAGGPGLKGNEGP------------SGPPGPAGSPGERGAAGSGGPIGPPGRPG 929

Query: 563  PPGYPGKQGPHGHP------GPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG------ 610
            P G PG  G  G P      GP G  G+ G VG  G  GP G  GE GD GEVG      
Sbjct: 930  PQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKG 989

Query: 611  ----RGHPGMPGPPGIPGLPGRPGQA----------------INGKDGDRGSPGAPGEAG 650
                +G  G PGPPG  G  G+PG A                  G +G RG  G PG  G
Sbjct: 990  TKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIG 1049

Query: 651  RPGLPGPVGLPG 662
              GLPGP G  G
Sbjct: 1050 LQGLPGPSGEKG 1061



 Score =  484 bits (1246), Expect = e-136
 Identities = 291/702 (41%), Positives = 353/702 (50%), Gaps = 82/702 (11%)

Query: 33  GPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT------ 86
           GPPGP GP G+ G  GI G+   PG  G PG +G PG+AG  G DG PG  G +      
Sbjct: 292 GPPGPEGPAGLIGPPGIQGN---PGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFR 348

Query: 87  --GAKGEPGPMGIPGVKGQP---------GLPGPPGLPG-PGFAGPPGPPGPVGLPGEIG 134
                G+ GP+ +   + Q           L GPPG  G  G  GP G PG  GL GE G
Sbjct: 349 FGSGGGDKGPV-VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESG 407

Query: 135 IRGPKGDPGPDGPSGPPGPPGKPGRPGT--IQGLEGSADFLCPTNCPPGMKGPPGLQGVK 192
             GP+G  GP G +GPPG  G+ GR G    +G+ G           PG+KG  G  G+ 
Sbjct: 408 DLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGD----------PGVKGDRGFDGLP 457

Query: 193 GHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYK 252
           G  G++G  GD G QG PGP G+ G  G+ G  GP G  G  G  G+ GPKG  G  G  
Sbjct: 458 GLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPP 517

Query: 253 GMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTP 312
           G+ G  G  GP G  GP+G PG  G++G  G+ G+ GPQG  GP G  GP G  G  G P
Sbjct: 518 GVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMP 577

Query: 313 GTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEP 372
           G+ G  G  G+ G PG+ G+QG +G  G  G  G  G +G  G +GL G  G  G++G P
Sbjct: 578 GSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFP 637

Query: 373 GPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSP 432
           G +G+IG +G  G+ G  G RG  G  GP+GR GP G+ GPPG+ G +G  GV G  G P
Sbjct: 638 GFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYP 697

Query: 433 GKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGP------------- 479
           G+ GP+G +G PG  G  GEKG +G SG+ GP+G++G  G  G  GP             
Sbjct: 698 GRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTS 757

Query: 480 --SGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQL 537
              G  G PG +G PGP GP G  G +G PG PG+ G+ G         +V  +      
Sbjct: 758 GGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRG---EVGFQGKTGPP 814

Query: 538 AEVAVSAKREALGAVGMM------GPPGP------------------PGPPGYPGKQGP- 572
               V   + A G  G M      GPPGP                  PGPPG PGK GP 
Sbjct: 815 GPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPA 874

Query: 573 --HGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMP-GPPGIPGLPGRP 629
              G PG RG+PG  G  G  GN GP G  G  G PGE G    G P GPPG PG  G P
Sbjct: 875 GLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPP 934

Query: 630 GQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLG 671
           G A  G+ G  G  G  G  GR G+ GPVGLPG   P    G
Sbjct: 935 GAA--GEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAG 974



 Score =  380 bits (977), Expect = e-105
 Identities = 254/633 (40%), Positives = 287/633 (45%), Gaps = 148/633 (23%)

Query: 175 PTNCPPGMKGPPGLQGVKGHAGKRGILGDPGH--QGKPGPKGD---VGASGEQGIPGPPG 229
           P N  P  +   G +G+KG  G+  +L +PG   +G PGP+G    +G  G QG PGP G
Sbjct: 258 PQNQEPQSQAAHGPRGLKGEKGEPAVL-EPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVG 316

Query: 230 PQGIRGYPGMAGPKGETGPHG--------------------------------------- 250
             G RG PG AG  G  G  G                                       
Sbjct: 317 DPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARL 376

Query: 251 -YKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKD 309
             +G  G +G TG PG  G  G PG  GE GD G  G RGPQG+TGP G  G  G  G D
Sbjct: 377 ALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGAD 436

Query: 310 GT---PGTPGMKGSAGQAGQPGSPGHQ------GLAGVPGQPGTKGGPGDQGEPGPQGLP 360
           G    PG PG+KG  G  G PG PG +      G  G+PG PG  G  GD GE GP+GLP
Sbjct: 437 GARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLP 496

Query: 361 GFS---------GPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQ---------PGPQ 402
           G S         GPPG  G PG RG  GPQG  G  G QGE GP GQ         PGPQ
Sbjct: 497 GESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQ 556

Query: 403 GRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGK---------------------TGPRGKV 441
           G  GP GE+GP G PG  G+PG  G  G PGK                      GPRG  
Sbjct: 557 GAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVK 616

Query: 442 GDPGVAGLPGEKGEKGESGEP---------------------------GPKGQQGVRGEP 474
           G  G+ GL G KGEKGE G P                           GPKG+ G  G+P
Sbjct: 617 GVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDP 676

Query: 475 GYP---GPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALK 531
           G P   G  G  G PG+ GYPG  GP+G  G  G PG  G +G  G         +    
Sbjct: 677 GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 736

Query: 532 MLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVP------GIV 585
             + Q      + K  A G  G  GP GPPG  G PG QGP+G PGP+G P      G+ 
Sbjct: 737 GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLP 796

Query: 586 GAVGQIGNTGPKGKRGEKGDPGEVG-------------RGHPGMPGPPGIPGLPGRPGQA 632
           G  GQ G  G +GK G  G PG VG             RGHPG PGPPG  GLPG  G+ 
Sbjct: 797 GHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGK- 855

Query: 633 INGKDGDRGSPGAPGE---AGRPGLPGPVGLPG 662
             G  GD G PGAPG+   AG  G PG  GLPG
Sbjct: 856 -EGTKGDPGPPGAPGKDGPAGLRGFPGERGLPG 887



 Score =  293 bits (749), Expect = 5e-79
 Identities = 204/551 (37%), Positives = 244/551 (44%), Gaps = 82/551 (14%)

Query: 178 CPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYP 237
           C  G +  P  Q  + H  +R     P    +P  +        Q   GP G +G +G P
Sbjct: 228 CEGGQRERP--QNQQPHRAQRSPQQQPSRLHRPQNQ----EPQSQAAHGPRGLKGEKGEP 281

Query: 238 GMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRG---PPGRAGEKGDEGSPGIRGPQG-- 292
            +  P          GM+      GPPG EGP G   PPG  G  G  G PG RGP G  
Sbjct: 282 AVLEP----------GML----VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA 327

Query: 293 -ITGPKGATGPPGIN-------GKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGT 344
            + G  GA GPPG +       G  G    P +     QA          L G PG  G 
Sbjct: 328 GLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGY 387

Query: 345 KGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGR 404
            G PG  G+PG  GL G SG  G +G  GP+G  GP G  G++G  G  G  G PG  G 
Sbjct: 388 TGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGV 447

Query: 405 QGPKGEQGPPGIP---------GPQGLPGVKGD------------KGSPGKTGPRGKVGD 443
           +G +G  G PG+P         G QGLPG  G+            +G PG++GPRG +G 
Sbjct: 448 KGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGP 507

Query: 444 PGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGN 503
            G  G+PG  G +G  G  GPKG  G +GE   PGP G  G PG QG PGP G  G  G 
Sbjct: 508 KGPPGIPGPPGVRGMDGPQGPKGSLGPQGE---PGPPGQQGTPGTQGLPGPQGAIGPHGE 564

Query: 504 RGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGP 563
           +G  G+PG  G+ G D    H                    K    G  G  GP GP GP
Sbjct: 565 KGPQGKPGLPGMPGSDGPPGH------------------PGKEGPPGTKGNQGPSGPQGP 606

Query: 564 PGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG----RGHPGMPGP 619
            GYPG +G  G  G RG+ G  G  G+ G  G KG  G KGD GEVG    RG  G  GP
Sbjct: 607 LGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGP 666

Query: 620 PGIPGLPGRPG-QAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASA 678
            G  G  G PG   + G+ G  G PG PG  GR G  G +G PGF  P A     A   +
Sbjct: 667 KGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGF--PGASGEKGARGLS 724

Query: 679 RLTEPGSIKGP 689
             + P   +GP
Sbjct: 725 GKSGPRGERGP 735



 Score =  274 bits (701), Expect = 2e-73
 Identities = 157/350 (44%), Positives = 182/350 (52%), Gaps = 30/350 (8%)

Query: 26   RGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGL 85
            RGP G  G  GP GPPG  G+ G  G+ G PG++G PG +GEPG  GP G  G+    G 
Sbjct: 1078 RGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGE---KGE 1134

Query: 86   TGAKGEPGPMGIPGVKGQPGLPGPPGLPGP-GFAGPPGPPGPVGLPGEIGIRGPKGDPGP 144
            +G  GEPGP   PG KG  G  GP G PGP GF G PGPPG  G  G+ G +G +G+ G 
Sbjct: 1135 SGQPGEPGP---PGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGE 1191

Query: 145  DGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDP 204
             G  G PGP G+ G PG                 P G +GP G  G +G  G +G  GDP
Sbjct: 1192 PGQPGSPGPTGENGPPG-----------------PLGKRGPAGSPGSEGRQGGKGAKGDP 1234

Query: 205  GHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPP 264
            G  G PG  G VG +G     G PGP G+RG PG  G +G  G     G  G  G  GPP
Sbjct: 1235 GAIGAPGKTGPVGPAGP---AGKPGPDGLRGLPGSVGQQGRPGA---TGQAGPPGPVGPP 1288

Query: 265  GEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQA 324
            G  G RG  G  GEKG  G  G+ GP G  G KG  G PG  G  G  G  G+ G++G  
Sbjct: 1289 GLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPI 1348

Query: 325  GQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGP 374
            G  G PG  G AG  G  G  G  G +GE G QG PG  GPPG+  +P P
Sbjct: 1349 GPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1398



 Score =  132 bits (332), Expect = 1e-30
 Identities = 86/206 (41%), Positives = 98/206 (47%), Gaps = 44/206 (21%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGI---------------DGDNGPPGKAGPPG-------- 63
            G PG+ GP GP GP G PG DG+                G  GPPG  GPPG        
Sbjct: 1238 GAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDA 1297

Query: 64   ----PKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGF-A 118
                 KG PG  G  GP   PG  G  G +G PGP G PG KG+ G+PG  G  GPG   
Sbjct: 1298 GAKGEKGHPGLIGLIGP---PGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP 1354

Query: 119  GPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQ-------GLEGS-- 169
            G PGP GP G  G  G  GPKG+ G  GP G PGPPG+  +P  IQ        ++GS  
Sbjct: 1355 GLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRL 1414

Query: 170  --ADFLCPTNCPPGMKGPPGLQGVKG 193
               D   PT   PG   P GL+ + G
Sbjct: 1415 MQEDEAIPTGGAPG--SPGGLEEIFG 1438



 Score =  103 bits (258), Expect = 4e-22
 Identities = 66/174 (37%), Positives = 80/174 (45%), Gaps = 31/174 (17%)

Query: 27   GPPGERGPPGPPGPPGVPG------------------------SDGIDGDNGPPGKAGPP 62
            G  G+ GPPGP GPPG+PG                          G  GD G PG  G P
Sbjct: 1274 GATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSP 1333

Query: 63   GPKGE---PGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAG 119
            G KGE   PG +GP GP G PG+ G  G KG  G  G  G KG+ G+ GPPG PGP   G
Sbjct: 1334 GQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGP--PG 1391

Query: 120  PPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFL 173
                P P+ +P +            +  + P G  G PG PG ++ + GS D L
Sbjct: 1392 EVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTG--GAPGSPGGLEEIFGSLDSL 1443


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score =  516 bits (1330), Expect = e-146
 Identities = 306/714 (42%), Positives = 352/714 (49%), Gaps = 70/714 (9%)

Query: 20   LALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGK 79
            L +  + G PG +GP G  G PG PG+ G  G  G  GK+GP G +G  G  G  GP G 
Sbjct: 795  LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 854

Query: 80   PGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPK 139
             G  G  G  G  GP G PG +G PG  GP G PGP   GPPGPPG  GLPG  G RG  
Sbjct: 855  TGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP--KGPPGPPGKDGLPGHPGQRGEV 912

Query: 140  GDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRG 199
            G  G  GP GPPG  G  G  G   G  G           PG  GPPG QG+ G AGK G
Sbjct: 913  GFQGKTGPPGPPGVVGPQGAAGET-GPMGERGH-------PGPPGPPGEQGLPGTAGKEG 964

Query: 200  ILGDPGHQGKPG---PKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVG 256
              GDPG  G PG   P G  G  GE+G+PG  G  G++G  G +GP G  G  G +G  G
Sbjct: 965  TKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAG 1024

Query: 257  AIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGP------QGITGPKGATGPPGINGKDG 310
            + G  GPPG  GP+GPPG AGEKG  G  G  GP      QG  G  G  GPPG+ G+DG
Sbjct: 1025 SGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDG 1084

Query: 311  TPGT---PGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPG 367
              G    PG KG+ G  G+ G PG  G  G  GQPG  G  G+ G  GPQG  G  G  G
Sbjct: 1085 DKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEG 1144

Query: 368  KEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKG 427
              G  GP G IG QG+ G  G++GE G VG  GP G  GP+G  GP G  GPQG PG  G
Sbjct: 1145 TRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVG 1204

Query: 428  DKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGA-- 485
            + G PG+ G  G+ G PG+ G PG KG +GE GE G  GQ G  G PG  GP+GD G   
Sbjct: 1205 NLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKG 1264

Query: 486  -PGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSA 544
             PG  G+PG PGP G  G RG  G  G +G +G                  Q      + 
Sbjct: 1265 NPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG---------------QPGSPGPTG 1309

Query: 545  KREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKG 604
            +    G +G  GP G PG  G  G +G  G PG  G PG  G VG  G  G  G  G +G
Sbjct: 1310 ENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRG 1369

Query: 605  DPGEVGR-------GHPGMPGPPGIPGLPGRPGQA----------------INGKDGDRG 641
             PG VG+       G  G PGP G PGLPG  G A                  G+ G++G
Sbjct: 1370 LPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKG 1429

Query: 642  SPGAPGEAGRPGLPGPVGLPGFCEPAACLG-------ASAYASARLTEPGSIKG 688
              G PG  G PG  G +G+PG   P    G       A    +   T PG  KG
Sbjct: 1430 DRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKG 1483



 Score =  503 bits (1295), Expect = e-142
 Identities = 330/789 (41%), Positives = 380/789 (48%), Gaps = 122/789 (15%)

Query: 14   LLQVVVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNG---------PPGKAGPPGP 64
            +LQ   LAL   RGPPG  G  G PGP G PGS G+ G++G         P G  GPPG 
Sbjct: 477  ILQQARLAL---RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGK 533

Query: 65   KGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQ------PGLPGPPG------- 111
             G  G+AG DG  G PG  G+ G +G  G  G+PG KG        GLPGPPG       
Sbjct: 534  AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGD 593

Query: 112  --------LPGP----GFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGR 159
                    LPG     G  GP GPPG  G PG  G+ GP+G  G  GP G PGPPG+ G 
Sbjct: 594  DGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT 653

Query: 160  PGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGAS 219
            PGT QGL G    + P     G KGP G  G+ G  G  G  G PG +G PG KG+ G S
Sbjct: 654  PGT-QGLPGPQGAIGPH----GEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS 708

Query: 220  GEQGIPGPPGPQG------IRGYPGMAGPKGETGPHGYKGMVGA------IGATGPPGEE 267
            G QG  G PGP+G      IRG  G  G KGE G  G+KG +G       +G  G  GE+
Sbjct: 709  GPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED 768

Query: 268  GPRGPPGRAGEKGDEGSPGIRGPQGITG------------PKGATGPPG----------- 304
            GP GP GR G  GD G PG+ G +G  G            PKG+ G PG           
Sbjct: 769  GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGAR 828

Query: 305  -INGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFS 363
             ++GK G  G  G  G  GQ G  G+ G  G  G  G  G  G PG++G PGPQG  GF 
Sbjct: 829  GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 888

Query: 364  GP------PGKEG---EPGPRGEIG---------PQGIMGQKGDQGERGPVGQPGPQGRQ 405
            GP      PGK+G    PG RGE+G         P G++G +G  GE GP+G+ G  G  
Sbjct: 889  GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 948

Query: 406  GPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGE------KGEKGES 459
            GP GEQG PG  G +G  G  G  G+PGK GP G  G PG  GLPG       KG +G S
Sbjct: 949  GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPS 1008

Query: 460  GEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRD 519
            G PGP G  G RG  G  GP G  G PG QG PG  G +G+ G +G  G  GR GV+G  
Sbjct: 1009 GPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPV 1068

Query: 520  ATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGP------------PGYP 567
                      +        EV    ++   G  G  GPPGPPGP             G P
Sbjct: 1069 GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEP 1128

Query: 568  GKQGPHGH---PGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-RGHPGMPGPPGIP 623
            G +GP GH    G  G  G  G  G IG  G  G  GEKG+ G+VG  G PG PGP G  
Sbjct: 1129 GARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPA 1188

Query: 624  GLPGRPG-QAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASARLTE 682
            G  G  G Q   G  G+ G PG  GE G  G PG  G PG   P    G     S +  E
Sbjct: 1189 GPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG-ESGQPGE 1247

Query: 683  PG--SIKGP 689
            PG    KGP
Sbjct: 1248 PGPPGPKGP 1256



 Score =  492 bits (1267), Expect = e-139
 Identities = 306/713 (42%), Positives = 363/713 (50%), Gaps = 110/713 (15%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
            GP G+RGP G  G  G  G+ G DG +GPPG+ G PGP+G  G  GP GP G PG DGL 
Sbjct: 844  GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLP 903

Query: 87   GAKGEPGPMGIPGVKGQPGLPGPPGLPGP-------------GFAGPPGPPGPVGLPGEI 133
            G    PG  G  G +G+ G PGPPG+ GP             G  GPPGPPG  GLPG  
Sbjct: 904  G---HPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTA 960

Query: 134  GIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADF--LCPTNCPPGMKGPPGLQGV 191
            G  G KGDPGP G  G  GP G  G PG  +GL G+A    L     P G  GP G  G 
Sbjct: 961  GKEGTKGDPGPPGAPGKDGPAGLRGFPGE-RGLPGTAGGPGLKGNEGPSGPPGPAGSPGE 1019

Query: 192  KGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGP---------QGIRGYPGMAGP 242
            +G AG  G +G PG   +PGP+G  GA+GE+G+PG  GP         QG  G PG AGP
Sbjct: 1020 RGAAGSGGPIGPPG---RPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP 1076

Query: 243  ---------KGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGI 293
                     KGE G  G KG  G  G  GPPG  GP GP G+ G  G +G PG RGPQG 
Sbjct: 1077 PGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGH 1136

Query: 294  TGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGE 353
             G KG  G  G NG    PG  G++G  G +G+ G  G  G  G PG PG +G  G  G 
Sbjct: 1137 FGAKGDEGTRGFNGP---PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGA 1193

Query: 354  PGPQGLPGFSG---PPGKEGEPGP------RGEIGPQGIMGQKGDQGERGPVGQPGPQGR 404
             GPQG PG  G   PPG++GEPG       +GE G +G  G++G++GE G  G+PGP G 
Sbjct: 1194 DGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGP 1253

Query: 405  QGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVG------DPGVAGLPGEKGEKGE 458
            +GP G+ GP G PGP G PG   D G PG+ GPRG+ G      + G  G PG  G  GE
Sbjct: 1254 KGPTGDDGPKGNPGPVGFPG---DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGE 1310

Query: 459  SGEPGPKGQQGVRGEPGYPG------PSGDAGAPGVQGYPGPPGPRGLAGN------RGV 506
            +G PGP G++G  G PG  G        GD GA G  G  GP GP G AG       RG+
Sbjct: 1311 NGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGL 1370

Query: 507  PGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGP------ 560
            PG  G+QG  G          V    L     +     ++   G +G++GPPG       
Sbjct: 1371 PGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGD 1430

Query: 561  ---PGPPGYPGKQGPHGHPG---------PRGVPGIVGAVGQIGNTGPKGKRGEKGDPGE 608
               PGP G PG++G  G PG         P G+PG  G  G  G TGP G +GEKG    
Sbjct: 1431 RGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKG---- 1486

Query: 609  VGRGHPGMPGPPG--IPGLP-GRPGQAINGKDGDR-----------GSPGAPG 647
              +G PG PGPPG  I  LP   P +     DG R           G+PG+PG
Sbjct: 1487 -VQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1538



 Score =  488 bits (1257), Expect = e-138
 Identities = 308/792 (38%), Positives = 358/792 (45%), Gaps = 174/792 (21%)

Query: 25   IRGPPGERGPPGPPGPPGV---PGSDGIDGDNGPPGKA---------------------- 59
            + GPPG  GP G  GPPG+   PG  G  G+ GPPG+A                      
Sbjct: 397  VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRF 456

Query: 60   ------------------------------GPPGPKGEPGKAGPDGPDGKPGIDGLTGAK 89
                                          GPPGP G  G+ GP G  G PG+ G +G  
Sbjct: 457  GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 516

Query: 90   GEPGPM---------------------------GIPGVKGQPGLPGPPGLPG-------- 114
            G  GP                            G PGVKG  G  G PGLPG        
Sbjct: 517  GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDT 576

Query: 115  --PGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADF 172
               G  GPPG  G  G  GEIG RG  G+ GP G  GP GPPG PG PG ++G++G    
Sbjct: 577  GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPG-VRGMDGPQG- 634

Query: 173  LCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQG 232
                  P G  GP G  G  G  G  G  G PG QG  GP G+ G  G+ G+PG PG  G
Sbjct: 635  ------PKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 688

Query: 233  IRGYPGMAGP---KGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRG 289
              G+PG  GP   KG  GP G +G +G  G  G  G +G RG  G  GEKG++G PG +G
Sbjct: 689  PPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKG 748

Query: 290  PQGITGPKGATGPPGINGKD------------GTPGTPGMKGSAGQAGQPGSPGHQGLAG 337
              G+ G +G  G PG  G+D            G PG PG+ G  G+ G PG PG+ G  G
Sbjct: 749  DIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQG 808

Query: 338  VPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQ------- 390
              G  G  G PG  GE G +GL G SGP G+ G  GPRG+ GP+G  G+ G +       
Sbjct: 809  PKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDG 868

Query: 391  -----GERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGK---VG 442
                 GERG  G  GP G  GPKG  GPPG  G  G PG +G+ G  GKTGP G    VG
Sbjct: 869  PHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVG 928

Query: 443  DPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAG 502
              G AG  G  GE+G  G PGP G+QG+ G  G  G  GD G PG  G  GP G RG  G
Sbjct: 929  PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG 988

Query: 503  NRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPG 562
             RG+PG  G  G++G +                         +R A G+ G +GPPG PG
Sbjct: 989  ERGLPGTAGGPGLKGNEGP------------SGPPGPAGSPGERGAAGSGGPIGPPGRPG 1036

Query: 563  PPGYPGKQGPHGHP------GPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG------ 610
            P G PG  G  G P      GP G  G+ G VG  G  GP G  GE GD GEVG      
Sbjct: 1037 PQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKG 1096

Query: 611  ----RGHPGMPGPPGIPGLPGRPGQA----------------INGKDGDRGSPGAPGEAG 650
                +G  G PGPPG  G  G+PG A                  G +G RG  G PG  G
Sbjct: 1097 TKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIG 1156

Query: 651  RPGLPGPVGLPG 662
              GLPGP G  G
Sbjct: 1157 LQGLPGPSGEKG 1168



 Score =  484 bits (1246), Expect = e-136
 Identities = 291/702 (41%), Positives = 353/702 (50%), Gaps = 82/702 (11%)

Query: 33   GPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT------ 86
            GPPGP GP G+ G  GI G+   PG  G PG +G PG+AG  G DG PG  G +      
Sbjct: 399  GPPGPEGPAGLIGPPGIQGN---PGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFR 455

Query: 87   --GAKGEPGPMGIPGVKGQP---------GLPGPPGLPG-PGFAGPPGPPGPVGLPGEIG 134
                 G+ GP+ +   + Q           L GPPG  G  G  GP G PG  GL GE G
Sbjct: 456  FGSGGGDKGPV-VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESG 514

Query: 135  IRGPKGDPGPDGPSGPPGPPGKPGRPGT--IQGLEGSADFLCPTNCPPGMKGPPGLQGVK 192
              GP+G  GP G +GPPG  G+ GR G    +G+ G           PG+KG  G  G+ 
Sbjct: 515  DLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGD----------PGVKGDRGFDGLP 564

Query: 193  GHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYK 252
            G  G++G  GD G QG PGP G+ G  G+ G  GP G  G  G  G+ GPKG  G  G  
Sbjct: 565  GLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPP 624

Query: 253  GMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTP 312
            G+ G  G  GP G  GP+G PG  G++G  G+ G+ GPQG  GP G  GP G  G  G P
Sbjct: 625  GVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMP 684

Query: 313  GTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEP 372
            G+ G  G  G+ G PG+ G+QG +G  G  G  G  G +G  G +GL G  G  G++G P
Sbjct: 685  GSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFP 744

Query: 373  GPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSP 432
            G +G+IG +G  G+ G  G RG  G  GP+GR GP G+ GPPG+ G +G  GV G  G P
Sbjct: 745  GFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYP 804

Query: 433  GKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGP------------- 479
            G+ GP+G +G PG  G  GEKG +G SG+ GP+G++G  G  G  GP             
Sbjct: 805  GRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTS 864

Query: 480  --SGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQL 537
               G  G PG +G PGP GP G  G +G PG PG+ G+ G         +V  +      
Sbjct: 865  GGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRG---EVGFQGKTGPP 921

Query: 538  AEVAVSAKREALGAVGMM------GPPGP------------------PGPPGYPGKQGP- 572
                V   + A G  G M      GPPGP                  PGPPG PGK GP 
Sbjct: 922  GPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPA 981

Query: 573  --HGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMP-GPPGIPGLPGRP 629
               G PG RG+PG  G  G  GN GP G  G  G PGE G    G P GPPG PG  G P
Sbjct: 982  GLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPP 1041

Query: 630  GQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLG 671
            G A  G+ G  G  G  G  GR G+ GPVGLPG   P    G
Sbjct: 1042 GAA--GEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAG 1081



 Score =  292 bits (747), Expect = 8e-79
 Identities = 202/533 (37%), Positives = 236/533 (44%), Gaps = 86/533 (16%)

Query: 220 GEQGIPGPPGPQGIR-GYPGMAGPKGETGP-------------HGYKGMVGAIG------ 259
           GE G   P GP     GY      + E GP             HG +G+ G  G      
Sbjct: 333 GEGGTDPPEGPYDYTYGYGDDYREETELGPALSAETAHSGAAAHGPRGLKGEKGEPAVLE 392

Query: 260 ----ATGPPGEEGPRG---PPGRAGEKGDEGSPGIRGPQG---ITGPKGATGPPGIN--- 306
                 GPPG EGP G   PPG  G  G  G PG RGP G   + G  GA GPPG +   
Sbjct: 393 PGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLML 452

Query: 307 ----GKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGF 362
               G  G    P +     QA          L G PG  G  G PG  G+PG  GL G 
Sbjct: 453 PFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGE 512

Query: 363 SGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIP----- 417
           SG  G +G  GP+G  GP G  G++G  G  G  G PG  G +G +G  G PG+P     
Sbjct: 513 SGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGH 572

Query: 418 ----GPQGLPGVKGD------------KGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGE 461
               G QGLPG  G+            +G PG++GPRG +G  G  G+PG  G +G  G 
Sbjct: 573 RGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGP 632

Query: 462 PGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDAT 521
            GPKG  G +GE   PGP G  G PG QG PGP G  G  G +G  G+PG  G+ G D  
Sbjct: 633 QGPKGSLGPQGE---PGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGP 689

Query: 522 DQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGV 581
             H                    K    G  G  GP GP GP GYPG +G  G  G RG+
Sbjct: 690 PGH------------------PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGL 731

Query: 582 PGIVGAVGQIGNTGPKGKRGEKGDPGEVG----RGHPGMPGPPGIPGLPGRPG-QAINGK 636
            G  G  G+ G  G KG  G KGD GEVG    RG  G  GP G  G  G PG   + G+
Sbjct: 732 KGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGE 791

Query: 637 DGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASARLTEPGSIKGP 689
            G  G PG PG  GR G  G +G PGF  P A     A   +  + P   +GP
Sbjct: 792 KGKLGVPGLPGYPGRQGPKGSLGFPGF--PGASGEKGARGLSGKSGPRGERGP 842



 Score =  274 bits (701), Expect = 2e-73
 Identities = 157/350 (44%), Positives = 182/350 (52%), Gaps = 30/350 (8%)

Query: 26   RGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGL 85
            RGP G  G  GP GPPG  G+ G  G+ G PG++G PG +GEPG  GP G  G+    G 
Sbjct: 1185 RGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGE---KGE 1241

Query: 86   TGAKGEPGPMGIPGVKGQPGLPGPPGLPGP-GFAGPPGPPGPVGLPGEIGIRGPKGDPGP 144
            +G  GEPGP   PG KG  G  GP G PGP GF G PGPPG  G  G+ G +G +G+ G 
Sbjct: 1242 SGQPGEPGP---PGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGE 1298

Query: 145  DGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDP 204
             G  G PGP G+ G PG                 P G +GP G  G +G  G +G  GDP
Sbjct: 1299 PGQPGSPGPTGENGPPG-----------------PLGKRGPAGSPGSEGRQGGKGAKGDP 1341

Query: 205  GHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPP 264
            G  G PG  G VG +G     G PGP G+RG PG  G +G  G     G  G  G  GPP
Sbjct: 1342 GAIGAPGKTGPVGPAGP---AGKPGPDGLRGLPGSVGQQGRPGA---TGQAGPPGPVGPP 1395

Query: 265  GEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQA 324
            G  G RG  G  GEKG  G  G+ GP G  G KG  G PG  G  G  G  G+ G++G  
Sbjct: 1396 GLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPI 1455

Query: 325  GQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGP 374
            G  G PG  G AG  G  G  G  G +GE G QG PG  GPPG+  +P P
Sbjct: 1456 GPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1505



 Score =  132 bits (332), Expect = 1e-30
 Identities = 86/206 (41%), Positives = 98/206 (47%), Gaps = 44/206 (21%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGI---------------DGDNGPPGKAGPPG-------- 63
            G PG+ GP GP GP G PG DG+                G  GPPG  GPPG        
Sbjct: 1345 GAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDA 1404

Query: 64   ----PKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGF-A 118
                 KG PG  G  GP   PG  G  G +G PGP G PG KG+ G+PG  G  GPG   
Sbjct: 1405 GAKGEKGHPGLIGLIGP---PGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP 1461

Query: 119  GPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQ-------GLEGS-- 169
            G PGP GP G  G  G  GPKG+ G  GP G PGPPG+  +P  IQ        ++GS  
Sbjct: 1462 GLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRL 1521

Query: 170  --ADFLCPTNCPPGMKGPPGLQGVKG 193
               D   PT   PG   P GL+ + G
Sbjct: 1522 MQEDEAIPTGGAPG--SPGGLEEIFG 1545



 Score =  103 bits (258), Expect = 4e-22
 Identities = 66/174 (37%), Positives = 80/174 (45%), Gaps = 31/174 (17%)

Query: 27   GPPGERGPPGPPGPPGVPG------------------------SDGIDGDNGPPGKAGPP 62
            G  G+ GPPGP GPPG+PG                          G  GD G PG  G P
Sbjct: 1381 GATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSP 1440

Query: 63   GPKGE---PGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAG 119
            G KGE   PG +GP GP G PG+ G  G KG  G  G  G KG+ G+ GPPG PGP   G
Sbjct: 1441 GQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGP--PG 1498

Query: 120  PPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFL 173
                P P+ +P +            +  + P G  G PG PG ++ + GS D L
Sbjct: 1499 EVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTG--GAPGSPGGLEEIFGSLDSL 1550


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score =  510 bits (1314), Expect = e-144
 Identities = 304/743 (40%), Positives = 360/743 (48%), Gaps = 108/743 (14%)

Query: 25   IRGPPGERGPPGPPGPPG--------------VPGSDGI-------DGDNGPPGKAGPPG 63
            +RG PGE+GP G  G PG              +PG+ G+        G  GPPG  GPPG
Sbjct: 857  LRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPG 916

Query: 64   PKGEPGKAGPDGPDGKPGIDGLT----------------------GAKGEPGPMGIPGVK 101
            P G PG  G  G +G PG  GLT                      G +  PG +   G K
Sbjct: 917  PPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEK 976

Query: 102  GQPGLPGPPGLPG------------------------PGFAGPPGPPGPVGLPGEIGIRG 137
            G  G+PG PGL                          PG  G PG PGP GLPG+ G  G
Sbjct: 977  GDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEG 1036

Query: 138  P---KGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADF--LCPTNCPPGMKGPPGLQGVK 192
            P   +G PGP GP GPPG PG  G PG + GL+G      L      PG  G PG  G  
Sbjct: 1037 PPGMRGSPGPPGPIGPPGFPGAVGSPG-LPGLQGERGLTGLTGDKGEPGPPGQPGYPGAT 1095

Query: 193  GHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYK 252
            G  G  GI G+ G+ G  G KG+ G  G +G+PGPPGP G RG  G  G  GE G  G++
Sbjct: 1096 GPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQ 1155

Query: 253  GMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGK---- 308
            G  G  G  GPPG  G  G PG  G + ++GS GIRGP G+ G  G  GPPGI G     
Sbjct: 1156 GQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLD 1215

Query: 309  --DGTPGTPGMKGSAGQAG---------------QPGSPGHQGLAGVPGQPGTKGGPGDQ 351
              DG  G PG++G  G AG                PG PG +G  G PG PG+ G PG +
Sbjct: 1216 GLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAE 1275

Query: 352  GEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGI--MGQKGDQGERGPVGQPGPQGRQGPKG 409
            GEPG  G  G  GPPG  G PGP G+ GP GI  +G KGD+G  G  G  G  G+ GP G
Sbjct: 1276 GEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPG 1335

Query: 410  EQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQG 469
              GPPG PG  G  G +G  G  G  GP G  GDPG AG  G+ GEKG +G PG  G+ G
Sbjct: 1336 HPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSG 1395

Query: 470  VRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVA 529
              G  G PGP+G+      +G+PG PGP G  G  GVPG  G   +   D   + I    
Sbjct: 1396 SMGPVGPPGPAGE------RGHPGAPGPSGSPGLPGVPGSMG--DMVNYDEIKRFIRQEI 1447

Query: 530  LKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVG 589
            +KM  E++A      +      + M   PG PGPPG  G  G  G PG  G+PG +G  G
Sbjct: 1448 IKMFDERMAYYTSRMQFP----MEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREG 1503

Query: 590  QIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEA 649
            + G  G +G  G KG+ G++G G  G  G PG PG  G PG    G  G  G  G PG  
Sbjct: 1504 RQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGATGPMGQQGIPGIP 1563

Query: 650  GRPGLPGPVGLPGFCEPAACLGA 672
            G PG  G  G  G C P+ C GA
Sbjct: 1564 GPPGPMGQPGKAGHCNPSDCFGA 1586



 Score =  489 bits (1259), Expect = e-138
 Identities = 314/818 (38%), Positives = 362/818 (44%), Gaps = 175/818 (21%)

Query: 27   GPPGERGP-----PGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPG 81
            GP GE+GP     PG PG PG+PG  G  G  G  G+ GPPG +G  G  G  G  G PG
Sbjct: 745  GPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPG-RGVQGPQGEPGAPGLPG 803

Query: 82   IDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGD 141
            I GL G +G PGP G  G +G PG+ G  G  GP  A   GPPG  G  G+ G+RG  G+
Sbjct: 804  IQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGE 863

Query: 142  PGPDGPSGPPGPPGKPGRPGTI-QGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGI 200
             GP G  G PG    P +   I  G+ G+      ++  PG +GPPG+ G  G  G  G+
Sbjct: 864  KGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGL 923

Query: 201  LGDPGHQGKPGPKG----------------------------------DVGASGEQGIPG 226
             G PG+ G PG  G                                  + G  G+QGIPG
Sbjct: 924  QGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPG 983

Query: 227  PPG--------------------------PQGIRGYPGMAGPKGETGPHGYKGMVGAIGA 260
             PG                            G  G PG+ GP G  G  G +G  G  G+
Sbjct: 984  VPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGS 1043

Query: 261  TGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPG---INGKDGTPGTPGM 317
             GPPG  GP G PG  G  G  G  G RG  G+TG KG  GPPG     G  G PG PG+
Sbjct: 1044 PGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGI 1103

Query: 318  KG------SAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGE 371
            KG      SAG+ G+PG PG +GL G PG  G +G  G QG  G +G  GF G PG  G 
Sbjct: 1104 KGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGP 1163

Query: 372  PGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGS 431
            PGP G  G  G  G  G Q E+G  G  GP G  G  G  GPPGI GP GL G+ G  G 
Sbjct: 1164 PGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGK 1223

Query: 432  PGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGY 491
            PG  G  G  G PG+ G PG KG+ G  G PGPKG  G  G PG  G  G  G PG  G 
Sbjct: 1224 PGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGP 1283

Query: 492  PGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGA 551
             G PGP G  G  G PGQPG  G+            V LK       +   + +R   G 
Sbjct: 1284 QGRPGPPGHVGPPGPPGQPGPAGISA----------VGLK------GDRGATGERGLAGL 1327

Query: 552  VGMMGPPGPPGPPGY------------PGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGK 599
             G  GPPG PGPPG             PGKQG +G PGP+G P   GA GQ G  G KG+
Sbjct: 1328 PGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDP---GAAGQKGQAGEKGR 1384

Query: 600  RGEKGDPGEVG-------------RGHPGMPGP---PGIPGLPGRPGQAIN--------- 634
             G  G PG+ G             RGHPG PGP   PG+PG+PG  G  +N         
Sbjct: 1385 AGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIR 1444

Query: 635  ----------------------------------GKDGDRGSPGAPGEAGRP-------- 652
                                              GKDG  G PGAPG  G P        
Sbjct: 1445 QEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGR 1504

Query: 653  -GLPGPVGLPGFCEPAACLGASAYASARLTEPGSIKGP 689
             GLPG  GLPG       +G        L  P   +GP
Sbjct: 1505 QGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGP 1542



 Score =  465 bits (1197), Expect = e-131
 Identities = 310/815 (38%), Positives = 358/815 (43%), Gaps = 209/815 (25%)

Query: 26   RGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGP---------------PGPKGEPGK 70
            +G  GE GP G PGPPG  G  GI G  G P +  P               PGP GE G+
Sbjct: 601  KGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGE 660

Query: 71   AGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPG----PGFAGPPGPPGP 126
             GP G        GL G +G+ G  G+ G KG  G PG PG PG    PG +G PG  GP
Sbjct: 661  PGPPG-------FGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGP 713

Query: 127  VGLPGEIG---------------IRGPKGDPGPDGPSGPPGP--PGKPGRPGTIQGLEGS 169
             G  GE G               + G  G PGP G  GP G   PGKPG+PG + G++G 
Sbjct: 714  AGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPG-LPGVQG- 771

Query: 170  ADFLCPTNCPPGMKG------PPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQG 223
                     PPG+KG      PPG +GV+G  G+ G  G PG QG PGP+G  G +GE+G
Sbjct: 772  ---------PPGLKGVQGEPGPPG-RGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKG 821

Query: 224  IPGPPGPQGIRGYPGMAGPKGET--GPHGYKGMVGAIGATGPPGEEGPRGPPGRAGE--- 278
              G PG   ++G  G  GP G +  GP G  G  G  G  G PGE+GPRG  G  GE   
Sbjct: 822  AQGSPG---VKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSC 878

Query: 279  ------------------KGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGS 320
                               G    PG +GP GI GP G  G PG+ G  G  G PG  G 
Sbjct: 879  PSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGL 938

Query: 321  AGQAG----------------------------QPGSPGHQGLAGVPG------------ 340
              + G                            + G  G QG+ GVPG            
Sbjct: 939  TAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLE 998

Query: 341  --------------QPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQ 386
                           PG  G PG  G PG  G  G  GPPG  G PGP G IGP G  G 
Sbjct: 999  RPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGA 1058

Query: 387  KGD------QGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGK 440
             G       QGERG  G  G +G  GP G+ G PG  GP GLPG+KG++G  G  G +G+
Sbjct: 1059 VGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGE 1118

Query: 441  VGDPGVAGLPGE------KGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGP 494
             G PG  GLPG       +GE+G  G  G KG QG +G+PG+PGP G  G PG  G PGP
Sbjct: 1119 PGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGP 1178

Query: 495  PGPR------------GLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAV 542
            PGP+            GL G+ G PG PG QG  G D  D                    
Sbjct: 1179 PGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLD------------------GK 1220

Query: 543  SAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRG------VPGIVGAVGQIGNTGP 596
              K    G  G  GPPG  GPPG+ GK G  G PGP+G       PG  G  G  G  G 
Sbjct: 1221 DGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGA 1280

Query: 597  KGKRGEKGDPGEVGR-GHPGMPGPPGIP-----------------GLPGRPGQAINGKDG 638
             G +G  G PG VG  G PG PGP GI                  GLPG+PG    G  G
Sbjct: 1281 MGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPP--GHPG 1338

Query: 639  DRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGAS 673
              G PG  G AG+ G PG  G  G   P    GA+
Sbjct: 1339 PPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAA 1373



 Score =  460 bits (1184), Expect = e-129
 Identities = 327/901 (36%), Positives = 395/901 (43%), Gaps = 281/901 (31%)

Query: 16   QVVVLALAQIRGPPGERGP------PGPPGPPGVP---------------------GSDG 48
            ++ V+     +G PG  GP      PGPPG PG P                     GS G
Sbjct: 424  EICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSG 483

Query: 49   IDGDNGPPGKAGPPGPKGE---------------------PGKAGPDGPD-------GKP 80
            I G  GP GK G PG KGE                     PGK GP G         G P
Sbjct: 484  IPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDP 543

Query: 81   GIDGLTGAKGEP--------------------GPMGIPGVKGQPGLPGPPGLPGP----- 115
            GI G+ G KGEP                    G +G PG  G PGLPG  G+PG      
Sbjct: 544  GIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGF-GLPGLPGRAGVPGLKGEKG 602

Query: 116  --GFAGPPGPPGPVGLPGEIGIRGPKGD---------------------PGPDGPSGPPG 152
              G AGP G PGP G  G  GI+G KG+                     PGP G  G PG
Sbjct: 603  NFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPG 662

Query: 153  PP--GKPGRPGT-----IQGLEGSADFLCPTNCP-----PGMKGPPGLQGVKGHAGKRG- 199
            PP  G PG+ G      ++G +G A        P     PG+ G PG+QG  G  G++G 
Sbjct: 663  PPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGD 722

Query: 200  -----------ILGDPGHQGKPGPKGDVGAS--GEQGIPGPPGPQGIRGYPGMAGPKGET 246
                       +    G  G+PGPKG+ G    G  G PG PG  G++G PG+ G +GE 
Sbjct: 723  GCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEP 782

Query: 247  GP--HGYKGMVGAIGATGPPGEE---GPRGPPGRAGEKGDEGSPGIRGPQGITGPKGA-- 299
            GP   G +G  G  GA G PG +   GPRGPPG  GEKG +GSPG++G  G  GP GA  
Sbjct: 783  GPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASV 842

Query: 300  TGPPGINGKDGTP---GTPGMKGSAGQAGQPG-----SPGHQGLAGVPG----------Q 341
            +GPPG +G+ G     GTPG KG  G+ G+PG     S G    +G+PG          Q
Sbjct: 843  SGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQ 902

Query: 342  PGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRG---EIGP------------------ 380
            PG +G PG  G PGP G+PG  G PG  G PG  G   E+G                   
Sbjct: 903  PGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQG 962

Query: 381  ----QGIMGQKGDQGERGPVGQPG--------------------PQGRQGPKGEQGPPGI 416
                 G + +KG++G++G  G PG                        +G  G  G PG+
Sbjct: 963  QRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGL 1022

Query: 417  PGPQGLPGVKGDKGSP---GKTGPRGKVGDPGV------AGLPGEKGEKGESGEPGPKGQ 467
            PGP GLPG +G++G P   G  GP G +G PG        GLPG +GE+G +G  G KG+
Sbjct: 1023 PGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGE 1082

Query: 468  QGVRGEPGYPGPSGDAGAPGV------------QGYPGPPGPRGLAGNRGVPGQPGRQGV 515
             G  G+PGYPG +G  G PG+            +G PGPPG  GL G  G  G  G +G 
Sbjct: 1083 PGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGP 1142

Query: 516  EGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGH 575
            +G                         S ++   G  G  G PGPPGPPG+PGK G  G 
Sbjct: 1143 QGN------------------------SGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGP 1178

Query: 576  PGPR---------------------GVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG---- 610
            PGP+                     G PGI G  G  G  G  GK G +GDPG  G    
Sbjct: 1179 PGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGL 1238

Query: 611  ---------RGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLP 661
                      GHPG+PGP G  G PG PG    G+ G  G PGA G  GRPG PG VG P
Sbjct: 1239 MGPPGFKGKTGHPGLPGPKGDCGKPGPPGS--TGRPGAEGEPGAMGPQGRPGPPGHVGPP 1296

Query: 662  G 662
            G
Sbjct: 1297 G 1297



 Score =  459 bits (1180), Expect = e-129
 Identities = 309/783 (39%), Positives = 377/783 (48%), Gaps = 166/783 (21%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
            GP GE+G  G  GP G+PGS G   + G  G+ G  G KG PGK G DG  G+  + G  
Sbjct: 375  GPKGEKGESGALGPSGLPGSTG---EKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPK 431

Query: 87   GAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDG 146
            G KG+PG +G  G+ G+PG PG PG PG G  G PG PG        G  GPKGD G  G
Sbjct: 432  GQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPG--------GPPGPKGDKGSSG 483

Query: 147  PSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRG----ILG 202
              G  GP GKPG+PG ++G +G    +CPT  P G +   GL G  G  G+ G      G
Sbjct: 484  IPGKEGPGGKPGKPG-VKGEKGDPCEVCPT-LPEGFQNFVGLPGKPGPKGEPGDPVPARG 541

Query: 203  DPGHQGKPGPKGD-----------------VGASGEQGIPGPPGPQGIRGYPGMAGPKGE 245
            DPG QG  G KG+                  GASG+ G PG     G+ G PG AG  G 
Sbjct: 542  DPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPG----FGLPGLPGRAGVPGL 597

Query: 246  TGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGD---------EGSPGIRGPQGITGP 296
             G  G  G  G  G+ GPPG  GP G  G  GE  +         +G   +    G +G 
Sbjct: 598  KGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGE 657

Query: 297  KGATGPPGI-----NGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQ 351
            KG  GPPG       GK G  G  G KG AG  G PG+PG  G  G+ G+PG +G  G +
Sbjct: 658  KGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPK 717

Query: 352  GEPGP--QGLPGFSGP----PGKEGEPGPRGEIGPQGI-----MGQKGDQGERGPVG--- 397
            GE G      P   G      G+ G+PGP+GE GP+G+      GQ G  G +GP G   
Sbjct: 718  GEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKG 777

Query: 398  ---QPGPQGR--QGPKGEQGPPGIPGPQGLP---------GVKGDKGSPGKTGPRGKVGD 443
               +PGP GR  QGP+GE G PG+PG QGLP         G KG +GSPG  G  G VG 
Sbjct: 778  VQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGP 837

Query: 444  PG--VAGLPGEKGEKGES---GEPGPKGQQGVRGEPG----------------------- 475
            PG  V+G PG  G++G++   G PG KG +G +GEPG                       
Sbjct: 838  PGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWM 897

Query: 476  ----YPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQG----------------- 514
                 PGP G  G PG  G PG PG +G+ GN G+PGQPG                    
Sbjct: 898  GSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICG 957

Query: 515  --VEGRDATDQHIVDVALK-------------------MLQEQLAEVAVSAKREA-LGAV 552
              V+G+ A   ++V+   K                    L+   AE A     E   G V
Sbjct: 958  DCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCV 1017

Query: 553  GMMGPPGPPGPPGYPGKQGP------HGHPGPRGVPGIVGAVGQIGNTGPKGKR------ 600
            G  G PGPPG PG  G++GP       G PGP G PG  GAVG  G  G +G+R      
Sbjct: 1018 GSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLT 1077

Query: 601  GEKGDPGEVGR-GHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVG 659
            G+KG+PG  G+ G+PG  GPPG+PG+ G  G    G  G++G PG PG  G PG PGP G
Sbjct: 1078 GDKGEPGPPGQPGYPGATGPPGLPGIKGERG--YTGSAGEKGEPGPPGSEGLPGPPGPAG 1135

Query: 660  LPG 662
              G
Sbjct: 1136 PRG 1138



 Score =  452 bits (1163), Expect = e-127
 Identities = 310/852 (36%), Positives = 375/852 (44%), Gaps = 245/852 (28%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAG---PDGPDGKPGID 83
            GP G  G PGPPG PG PG  G+ G  G PG  GPPGPKG+ G +G    +GP GKPG  
Sbjct: 441  GPEGLAGEPGPPGLPGPPGI-GLPGTPGDPG--GPPGPKGDKGSSGIPGKEGPGGKPGKP 497

Query: 84   GLTGAKGEP---------------GPMGIPGVKGQPGLP----GPPGLPG---------- 114
            G+ G KG+P               G  G PG KG+PG P    G PG+ G          
Sbjct: 498  GVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCL 557

Query: 115  -----------------------PGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPP 151
                                   PGF G PG PG  G+PG   ++G KG+ G  GP+G P
Sbjct: 558  SCSSVVGAQHLVSSTGASGDVGSPGF-GLPGLPGRAGVPG---LKGEKGNFGEAGPAGSP 613

Query: 152  GPPGKPGRPGTIQGLEGSADFLCP--TNCPPG---MKGPPGLQGVKGHAGKRGILGDPGH 206
            GPPG  G P  I+G +G     CP  +N   G   +   PG  G KG  G  G  G PG 
Sbjct: 614  GPPGPVG-PAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGF-GLPGK 671

Query: 207  QGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKG------------- 253
            QGK G +G  G  G+ G PG PG  G  G PG++G  G  GP G KG             
Sbjct: 672  QGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQ 731

Query: 254  -----MVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPG--IN 306
                 M G  G  GP GE+GP G  GR G+ G  G PG++GP G+ G +G  GPPG  + 
Sbjct: 732  GTVTDMAGRPGQPGPKGEQGPEGV-GRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQ 790

Query: 307  GKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPP 366
            G  G PG PG+ G  G  G  G PG  G  G  G PG KG  G  G PG       SGPP
Sbjct: 791  GPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGAS----VSGPP 846

Query: 367  GKEGEPGP---RGEIGPQGIMGQKGDQGE---------------------RGPVGQPGPQ 402
            G++G+ G    RG  G +G  G+KG+ GE                      G   QPGPQ
Sbjct: 847  GRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQ 906

Query: 403  GRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGP------------------------- 437
            G  G  G  GPPG+PG QG+PG  G  G PG T                           
Sbjct: 907  GPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAH 966

Query: 438  ------RGKVGDPGVAGLPG------------------EKGEKGESGEPGPKGQQGVRGE 473
                  +G+ GD G+ G+PG                   +G+  E G+PG  G  G+ G 
Sbjct: 967  PGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSE-GDPGCVGSPGLPGP 1025

Query: 474  PGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKML 533
            PG PG  G+ G PG++G PGPPGP G  G  G  G PG  G++G                
Sbjct: 1026 PGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQG---------------- 1069

Query: 534  QEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGN 593
                       +R   G  G  G PGPPG PGYPG  GP G PG +G  G  G+ G+ G 
Sbjct: 1070 -----------ERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGE 1118

Query: 594  ---------------TGPKGKRGEKGDPGEVG----RGHPGMPGPPGIPGLPGRPG---- 630
                            GP+G+RG +G+ GE G    +G PG PGPPG PG PG+ G    
Sbjct: 1119 PGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGP 1178

Query: 631  ---QAINGKDGDRGS---PGAPGEAGRPGL---------------------PGPVGLPGF 663
               QA  G +G RG    PG+PG  G PG+                     PGP G PG 
Sbjct: 1179 PGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGL 1238

Query: 664  CEPAACLGASAY 675
              P    G + +
Sbjct: 1239 MGPPGFKGKTGH 1250



 Score =  395 bits (1015), Expect = e-110
 Identities = 228/539 (42%), Positives = 261/539 (48%), Gaps = 79/539 (14%)

Query: 22   LAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPG 81
            L  + G  GE GPPG PG PG  G  G+ G  G  G  G  G KGEP   GP G +G PG
Sbjct: 1073 LTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEP---GPPGSEGLPG 1129

Query: 82   IDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGD 141
              G  G +GE GP G  G KG  G  G PG PGP   GPPG PG VG PG  G +  KG 
Sbjct: 1130 PPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGP--PGPPGFPGKVGSPGPPGPQAEKGS 1187

Query: 142  PGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGIL 201
             G  GPSG PG PG PG                    PPG++GP GL G+ G  GK G+ 
Sbjct: 1188 EGIRGPSGLPGSPGPPG--------------------PPGIQGPAGLDGLDGKDGKPGLR 1227

Query: 202  GDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGAT 261
            GDPG  G PG  G  G  G+ G PG PGP+G  G PG  G  G  G  G  G +G  G  
Sbjct: 1228 GDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRP 1287

Query: 262  GPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSA 321
            GPPG  GP GPPG+ G  G   + G++G +G TG +G  G PG  G  G PG PG  G+ 
Sbjct: 1288 GPPGHVGPPGPPGQPGPAG-ISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTD 1346

Query: 322  GQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQ 381
            G AG+ G PG QG  G PG  G  G  G +G+ G +G  G  G PGK G  GP   +GP 
Sbjct: 1347 GAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGP---VGPP 1403

Query: 382  GIMGQKGDQGERGPVGQPGPQGRQGPKGEQ------------------------------ 411
            G  G++G  G  GP G PG  G  G  G+                               
Sbjct: 1404 GPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQ 1463

Query: 412  ------------GPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGES 459
                        GPPG  G  G PG  G  G PG+ G  G+ G PGV GLPG KGEKG+ 
Sbjct: 1464 FPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDI 1523

Query: 460  GEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGR 518
            G        G+ GE G PGP G  G PG  G  G  GP G  G  G+PG PG  G  G+
Sbjct: 1524 G-------IGIAGENGLPGPPGPQGPPG-YGKMGATGPMGQQGIPGIPGPPGPMGQPGK 1574



 Score =  339 bits (870), Expect = 4e-93
 Identities = 239/635 (37%), Positives = 283/635 (44%), Gaps = 149/635 (23%)

Query: 137 GPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAG 196
           GPKG  G  G  GPPG  G+ G  G    +  S D   P  C  G KG       KG +G
Sbjct: 334 GPKGGKGERGLPGPPGSKGEKGARGN-DCVRISPD--APLQCAEGPKGE------KGESG 384

Query: 197 KRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVG 256
             G  G PG  G+ G KG+ G  G +G+PG PG  G  G   + GPKG+ G  G+ G  G
Sbjct: 385 ALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEG 444

Query: 257 AIGATGPPGEEGPRG---------PPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGING 307
             G  GPPG  GP G         P G  G KGD+GS GI G +G   P G  G PG+ G
Sbjct: 445 LAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEG---PGGKPGKPGVKG 501

Query: 308 KDGTP---------------GTPGMKGSAGQAGQP----GSPGHQGLAGVPGQP------ 342
           + G P               G PG  G  G+ G P    G PG QG+ G  G+P      
Sbjct: 502 EKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSS 561

Query: 343 --------GTKGGPGDQGEP--GPQGLPGFSGPPGKEGE------------PGPRGEIGP 380
                    + G  GD G P  G  GLPG +G PG +GE            PGP G +GP
Sbjct: 562 VVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGP 621

Query: 381 QGIMGQKGDQGERGP------------VGQPGPQGRQGPKGEQGPP--GIPGPQGLPGVK 426
            GI G KG+  E  P            V  PGP G    KGE GPP  G+PG QG  G +
Sbjct: 622 AGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGE---KGEPGPPGFGLPGKQGKAGER 678

Query: 427 GDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQG---------------VR 471
           G KG  G  G  G  G PG  G PG  GE G  G  GPKG++G               + 
Sbjct: 679 GLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMA 738

Query: 472 GEPGYPGPSGD--------AGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQ 523
           G PG PGP G+         G PG  G PG  GP GL G +G PG PGR GV+G      
Sbjct: 739 GRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGR-GVQG------ 791

Query: 524 HIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPG 583
                                +  A G  G+ G PGP GPPG  G++G  G PG +G  G
Sbjct: 792 ------------------PQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATG 833

Query: 584 IVG-----AVGQIGNTGPKGKRGEKGDPGEVG-RGHPGMPGPPGIP--------GLPGRP 629
            VG       G  G  G +G+ G +G PGE G RG  G PG    P        G+PG P
Sbjct: 834 PVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAP 893

Query: 630 G--QAINGKDGDRGSPGAPGEAGRPGLPGPVGLPG 662
           G     + + G +G PG PG  G PG+PG  G+PG
Sbjct: 894 GLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPG 928



 Score =  323 bits (829), Expect = 3e-88
 Identities = 230/577 (39%), Positives = 273/577 (47%), Gaps = 106/577 (18%)

Query: 178 CPPGMKGPPGLQ------GVKGHAGKRGILGDPGHQGKPGPKGD--------------VG 217
           CPP + G           G KG  G+RG+ G PG +G+ G +G+               G
Sbjct: 316 CPPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEG 375

Query: 218 ASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAG 277
             GE+G  G  GP G+ G  G  G KGE G  G KG+ G  G  G PGE    GP     
Sbjct: 376 PKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGP----- 430

Query: 278 EKGDEGSPGIRGPQGITG---PKGATGPPGINGKDGTPGTP-GMKGSAGQAGQPGSPGHQ 333
            KG +G PG  GP+G+ G   P G  GPPGI G  GTPG P G  G  G  G  G PG +
Sbjct: 431 -KGQKGDPGFVGPEGLAGEPGPPGLPGPPGI-GLPGTPGDPGGPPGPKGDKGSSGIPGKE 488

Query: 334 GLAGVPGQPGTKGGPGDQGEPGPQ---------GLPGFSGPPGKEGEPGP-RGEIGPQGI 383
           G  G PG+PG KG  GD  E  P          GLPG  GP G+ G+P P RG+ G QGI
Sbjct: 489 GPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGI 548

Query: 384 MGQKGDQ--------GERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKT 435
            G+KG+         G +  V   G  G  G  G  G PG+PG  G+PG+KG+KG+ G+ 
Sbjct: 549 KGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPG-FGLPGLPGRAGVPGLKGEKGNFGEA 607

Query: 436 GPRGKVGDPG------------------------------VAGLPGEKGEKGESGEP--G 463
           GP G  G PG                              V  LPG  GEKGE G P  G
Sbjct: 608 GPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGFG 667

Query: 464 PKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDAT-- 521
             G+QG  GE G  G  GDAG PG  G PG  G  GL+G  GV G  G +G +G   T  
Sbjct: 668 LPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTAC 727

Query: 522 ---DQHIVDVALKMLQ-----EQLAE-VAVSAKREALGAVGMMGPP------GPPGPPGY 566
                 + D+A +  Q     EQ  E V    K    G  G+ GPP      G PGPPG 
Sbjct: 728 PSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPG- 786

Query: 567 PGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPG--IPG 624
            G QGP G PG  G+PGI G  G  G  GP G++G +G PG   +G  G  GPPG  + G
Sbjct: 787 RGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGV--KGATGPVGPPGASVSG 844

Query: 625 LPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLP 661
            PGR GQ   G+ G RG+PG  G  G  G PG    P
Sbjct: 845 PPGRDGQ--QGQTGLRGTPGEKGPRGEKGEPGECSCP 879



 Score =  259 bits (662), Expect = 6e-69
 Identities = 191/554 (34%), Positives = 231/554 (41%), Gaps = 127/554 (22%)

Query: 261 TGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGS 320
           TG   ++  RG         DE  P + G +        +GP G  G+ G PG PG KG 
Sbjct: 294 TGRISQKAERGAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGE 353

Query: 321 AGQAGQP-----------------GSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFS 363
            G  G                   G  G  G  G  G PG+ G  G +GE G  G+ G  
Sbjct: 354 KGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVP 413

Query: 364 GPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPG-PQGL 422
           G PG++G PG    IGP+G  G  G  G  G  G+PGP G  GP G  G PG PG P G 
Sbjct: 414 GKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGI-GLPGTPGDPGGP 472

Query: 423 PGVKGDKGS---PGKTGPRGKVGDPGV---------------------AGLPGEKGEKGE 458
           PG KGDKGS   PGK GP GK G PGV                      GLPG+ G KGE
Sbjct: 473 PGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGE 532

Query: 459 SGEP----GPKGQQGVRGEPGYP-----------------GPSGDAGAPGVQGYPGPPGP 497
            G+P    G  G QG++GE G P                 G SGD G+PG  G PG PG 
Sbjct: 533 PGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGF-GLPGLPGR 591

Query: 498 RGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGP 557
            G+ G +G  G  G  G  G       +    +K  + +  E   +      G V ++  
Sbjct: 592 AGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVAL 651

Query: 558 PGP------PGPPGY--PGKQGPHGH------------------PGPRGVPGIVGAVGQI 591
           PGP      PGPPG+  PGKQG  G                   PG  G PG+ G  G  
Sbjct: 652 PGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQ 711

Query: 592 GNTGPKGKRGE------------------------KGDPGEVGRGHPGMP---------G 618
           G  GPKG++G+                        KG+ G  G G PG P         G
Sbjct: 712 GPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQG 771

Query: 619 PPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAY--A 676
           PPG+ G+ G PG    G  G +G PGAPG  G  GLPGP G PG        G+     A
Sbjct: 772 PPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGA 831

Query: 677 SARLTEPG-SIKGP 689
           +  +  PG S+ GP
Sbjct: 832 TGPVGPPGASVSGP 845



 Score =  204 bits (518), Expect = 3e-52
 Identities = 149/429 (34%), Positives = 182/429 (42%), Gaps = 77/429 (17%)

Query: 317 MKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRG 376
           + G   Q  + G+  HQ  A     P   G         P G  G  G  G  G PG +G
Sbjct: 293 LTGRISQKAERGAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKG 352

Query: 377 EIG-----------------PQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGP 419
           E G                  +G  G+KG+ G  GP G PG  G +G KGE+G  GI G 
Sbjct: 353 EKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGV 412

Query: 420 QGLP------------GVKGDKGSPGKTGPRGKVGDPGVAGLPGEKG------EKGESGE 461
            G P            G KG KG PG  GP G  G+PG  GLPG  G           G 
Sbjct: 413 PGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGP 472

Query: 462 PGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPG------PRGLAGNRGVPGQPGRQGV 515
           PGPKG +G  G PG  GP G  G PGV+G  G P       P G     G+PG+PG +G 
Sbjct: 473 PGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGE 532

Query: 516 EGRDATDQHIVDVALKMLQEQLAEVAVSAKR--------EALGAVGMMGPP--GPPGPPG 565
            G     +   D  ++ ++ +  E  +S            + GA G +G P  G PG PG
Sbjct: 533 PGDPVPARG--DPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPG 590

Query: 566 YPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDP------------GEV---- 609
             G  G  G  G  G  G  G+ G  G  GP G +G KG+P            G+V    
Sbjct: 591 RAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVA 650

Query: 610 ---GRGHPGMPGPPGIPGLPGRPGQA----INGKDGDRGSPGAPGEAGRPGLPGPVGLPG 662
                G  G PGPPG  GLPG+ G+A    + G+ GD G+PG PG  G  G PG  G PG
Sbjct: 651 LPGPSGEKGEPGPPGF-GLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPG 709

Query: 663 FCEPAACLG 671
              PA   G
Sbjct: 710 VQGPAGPKG 718



 Score =  107 bits (267), Expect = 4e-23
 Identities = 67/170 (39%), Positives = 81/170 (47%), Gaps = 33/170 (19%)

Query: 20   LALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGK 79
            + +A   G PG  G  G PG PG PGS G+                  PG+ G +G  G 
Sbjct: 1466 MEMAAAPGRPGPPGKDGAPGRPGAPGSPGL------------------PGQIGREGRQGL 1507

Query: 80   PGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPK 139
            PG+ GL G KGE G +GI G+ G+ GLPGPP        GP GPPG     G++G  GP 
Sbjct: 1508 PGVRGLPGTKGEKGDIGI-GIAGENGLPGPP--------GPQGPPG----YGKMGATGPM 1554

Query: 140  GDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPP--GMKGPPG 187
            G  G  G  GPPGP G+PG+ G     +           PP   MKGP G
Sbjct: 1555 GQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKTMKGPFG 1604


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score =  507 bits (1305), Expect = e-143
 Identities = 325/773 (42%), Positives = 368/773 (47%), Gaps = 166/773 (21%)

Query: 23   AQIRGPPGERG-----------------PPGPPGPPGVPGSDGIDGDN-----GPPGKAG 60
            A+I GPPG RG                 PPGPPG PGV G  GI GD      GPPGK G
Sbjct: 715  AEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRG 774

Query: 61   PPG------PKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPG------LPG 108
              G      P+G+PG  G +GP G PG  GL G KG  G  G PGV G PG       PG
Sbjct: 775  LSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPG 834

Query: 109  PPGLPG-PGFAGPPGPPGPVGLPGEIGIRGP---KGDPGPDGPSGPPGPPGKPGRPGTI- 163
             PG PG PG+ G PG PG  G PG++G  GP   KG PG  G  G  GPPG PG PG   
Sbjct: 835  IPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFG 894

Query: 164  -QGLEGSADFLCPTNCPPGMKGP---PGLQGVKGHAGKRGILGDPGHQGKPGPKG----- 214
              GL G          PPG KGP   PG  G  G  GK G  G PG +G+PG KG     
Sbjct: 895  DDGLPG----------PPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLP 944

Query: 215  -DVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPP 273
             D G  G +G  GPPG +G        G  GE GP G  G  G  G  G PG +G RG P
Sbjct: 945  GDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEP 1004

Query: 274  GR----------AGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPG------M 317
            GR           GEKG  G PG  GP G TG +G  G PG+ G  G PG+PG      +
Sbjct: 1005 GRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGI 1064

Query: 318  KGSAGQAGQPGSPG-HQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRG 376
             G+ G  G  G P  H G  G  G+PG+ G PG  G  G QGLPG  GP G  G PGP G
Sbjct: 1065 DGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPG 1124

Query: 377  EIGPQGIMGQKGDQGERGP---VGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPG 433
              GP G  G  G  G RG    +G PGP+G QG  G  GPPGI GP G PG+ G  G  G
Sbjct: 1125 SSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKG 1184

Query: 434  KTGPRGK-----VGDPGVAGLPGEKGEKGESGEPG--PKGQQGVRGEPGYPGPSGDAGAP 486
            + G +G      VG PG  G+PG KGE+G+ G PG  P G +G +G PG PG SG  G  
Sbjct: 1185 QKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPA 1244

Query: 487  GVQGY-------PGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAE 539
            G  G        PGPPG +G  G  G  G PG  G+ G                      
Sbjct: 1245 GATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPG---------------------- 1282

Query: 540  VAVSAKREALGAVGMMGPPGPPGPPG---------------------YPGKQGPHGHPGP 578
             +V   R   G  G+ GPPGPPGPPG                     +PG QGPHG PGP
Sbjct: 1283 -SVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGP 1341

Query: 579  RGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGR--------GHPGMPGPPGIPGLPGRPG 630
             G  G+ G  G+ G TG  G RGE G P +V          G PGM GP G  GLPG  G
Sbjct: 1342 PGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRG 1401

Query: 631  QA---------INGKDGDRGSPGAPGEAGR------------PGLPGPVGLPG 662
             +         ++G+ G  G PG+PG  GR            PG PGP+G PG
Sbjct: 1402 PSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPG 1454



 Score =  493 bits (1269), Expect = e-139
 Identities = 319/797 (40%), Positives = 372/797 (46%), Gaps = 156/797 (19%)

Query: 26   RGPPGERG----------PPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDG 75
            RGP GE+G          P GPPGPPG+PG  G  GD G PG  G  G  G PG  GP G
Sbjct: 480  RGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPG 539

Query: 76   PDGKPGIDGLTGAKGEPGPM---GIPGVKGQPGLPGPPGLPGP-------GFAGPPGPPG 125
              GK G  G  G KG  G M    + G KG+ G  GPPG PG        G AG  G PG
Sbjct: 540  LPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPG 599

Query: 126  PVG-----LPGEIGIRGPKGDPGPDGPSGPPG-----PPGKPGRPGT-----IQGLEG-- 168
            P G      PG  G  GP G PG  GP GPPG     PPG+ G PG      ++G +G  
Sbjct: 600  PPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLK 659

Query: 169  --SADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPG 226
                D +      PG  GPPG  G  G  G  G  G PG  G  G KG  G  G   IPG
Sbjct: 660  GQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPG 719

Query: 227  PPGPQGIRGYPGMAGPKGET-----------GPHGYKGMVG--AIGATGPPGEEGPRGPP 273
            PPG +G  G PG  G KG +           G +G KG+ G  A G  GPPG+ G  G P
Sbjct: 720  PPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVP 779

Query: 274  GRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQ 333
            G  G +GD G PG  GP GI G  G  GP G  G  G PG PG  G + + G PG PG  
Sbjct: 780  GIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQP 839

Query: 334  GLAGVPGQPGTKGG---PGDQGEPGPQG------------------LPGFSGPPGKEGEP 372
            GL G PG PG  GG   PGD G PGP G                  LPG  GP G +G P
Sbjct: 840  GLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLP 899

Query: 373  GPRGEIGPQGI------------------MGQKGDQGERGPVGQPGPQGRQGPKGEQGP- 413
            GP G  GP+G+                   G KG+ GE+G  G PG +G +G KG  GP 
Sbjct: 900  GPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPP 959

Query: 414  -----------------PGIPGPQGLPGVKGDKGSPGKTGPR---GKVGDPGV-AGLPGE 452
                             PG PG  G PG +GDKG+PG  G R   G+ G PG   G PGE
Sbjct: 960  GDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGE 1019

Query: 453  KGEKGESGEPGPKGQQGVR---GEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVP-- 507
            KG+ G  G PGP G  G+R   G PG PG  G+ G+PG  G+ G  G RG  GN+G P  
Sbjct: 1020 KGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPAS 1079

Query: 508  --GQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPG 565
              G PG +G  G      H                  S ++   G  G+ GP G PG PG
Sbjct: 1080 HFGPPGPKGEPGSPGCPGHF---------------GASGEQ---GLPGIQGPRGSPGRPG 1121

Query: 566  YPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-RGHPGMPGPPGIPG 624
             PG  GP G PG  G+PG+ G  G++G+ GP+G +G+ G PG  G +G  G PG  G+ G
Sbjct: 1122 PPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHG 1181

Query: 625  LPGRPGQ---------------AINGKDGDRGSPGAPG--EAGRPGLPGPVGLPGFCEPA 667
            L G+ G                 I G  G+RG PG+PG    G  G  GP G PG   P 
Sbjct: 1182 LKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPP 1241

Query: 668  ACLGASAYASARLTEPG 684
               GA+  A   + +PG
Sbjct: 1242 GPAGATGRAPKDIPDPG 1258



 Score =  493 bits (1268), Expect = e-139
 Identities = 327/819 (39%), Positives = 382/819 (46%), Gaps = 164/819 (20%)

Query: 20   LALAQIRGPPGERGPPGP---PGPPGVPGSDGIDGDNGPPGKAGP-----------PGPK 65
            + +++++G  GERGP GP   PG PG  G DG  G+ G PG  G            PGP 
Sbjct: 559  MVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPL 618

Query: 66   GEPGKAGPDGP-----DGKPGIDGLTGAKGEPGPMGIPGVKGQ-----------PGLPGP 109
            G PGKAGP GP      G PG  G  G  G PG  G  G+KGQ           PG  GP
Sbjct: 619  GPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGP 678

Query: 110  PGLPGP----GFAGP---------------PGPPGPVGLPGEIGIRGPKGDPGPDG---- 146
            PG  GP    GF GP               PG PG   +PG  G RG  GDPG  G    
Sbjct: 679  PGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGS 738

Query: 147  -PSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGH------AGKRG 199
             P GPPGPPG PG  G  +G+ G   F      PPG +G  G+ G+KG        G  G
Sbjct: 739  SPVGPPGPPGSPGVNGQ-KGIPGDPAF--GHLGPPGKRGLSGVPGIKGPRGDPGCPGAEG 795

Query: 200  ILGDPGHQGKPGPKGDVGASGEQGIPGPP------GPQGIRGYPGMAGPKGETGPHGYKG 253
              G PG  G  GPKG  G +G  G+PGPP      G  GI G PG+ G  G  G  G KG
Sbjct: 796  PAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKG 855

Query: 254  MVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGP---QGITGPKGATGPPGINGKDG 310
              G +G  GP G +G  G PGR G  G  G PGI GP    G+ GP G  GP G+ G  G
Sbjct: 856  QPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPG 915

Query: 311  TPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGG------PGDQGEP---GPQGLPG 361
             PG  G  G+ G  G  G PG +G++G+PG  G +G       PGD+GE      +G PG
Sbjct: 916  FPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPG 975

Query: 362  FSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGP----------VGQPGPQGRQGP---- 407
              GPPG +G PG RG+ G  G+ G++G+ G  GP           GQPGP G  GP    
Sbjct: 976  EPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGST 1035

Query: 408  -----------KGEQGPPGIPGPQGLPGV------KGDKGSPGK-TGPRGKVGDPGVAGL 449
                        G+QG PG PGP G  G+      KG+KG P    GP G  G+PG  G 
Sbjct: 1036 GLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGC 1095

Query: 450  PGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYP---------GPPGPRGL 500
            PG  G  GE G PG +G +G  G PG PG SG  G PG  G P         G PGPRGL
Sbjct: 1096 PGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGL 1155

Query: 501  AGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREA--------LGAV 552
             G+ G+PG PG +G  G    +       L  L+ Q      S   +          G  
Sbjct: 1156 QGDPGIPGPPGIKGPSGSPGLN------GLHGLKGQKGTKGASGLHDVGPPGPVGIPGLK 1209

Query: 553  GMMGPPGPPG--PPGYPGKQGPHGHPGPRGVPGIVGAVGQI----------GNTGPKGKR 600
            G  G PG PG  PPG  GK+GP G PG  G PG  GA G+           G+ GP G  
Sbjct: 1210 GERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPD 1269

Query: 601  GEKGDPGEVG--------RGHP---GMPGPPGIPGLPGRPG----QAINGKDGDRGSPGA 645
            G +G PG  G        RG P   G+PGPPG PG PG PG       +GKDG +G  G 
Sbjct: 1270 GPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGF 1329

Query: 646  PGEAGRPGLPGPVGLPGFCEPAACLGASAYASARLTEPG 684
            PG  G  G PGP G  G   P    G +     R  EPG
Sbjct: 1330 PGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPR-GEPG 1367



 Score =  485 bits (1249), Expect = e-137
 Identities = 304/724 (41%), Positives = 359/724 (49%), Gaps = 95/724 (13%)

Query: 17   VVVLALAQIRGPPGERGPP---------GPPGPPGV--------------PGSDGIDGDN 53
            V+V     ++GPPG+ G P         GPPGPPG+              PG  G  G  
Sbjct: 357  VLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLP 416

Query: 54   GPPGKAGPPG----PKGEPGKAGPDGPDGKPGIDGLTGAK------GEPGPMGIPGVKGQ 103
            G PG+AG PG      G+PGK G  G  G PG+ GL G+       G PGP GI G  G 
Sbjct: 417  GLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGP 476

Query: 104  PGLPGPPGLPG-PGFA----GPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPG 158
            PG  GP G  G  G      GP GPPGP GLPG  G +G  G PG  G  G PGPPG  G
Sbjct: 477  PGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEG 536

Query: 159  RPGTIQGLEGSADFLCPTNCPPGMKGPPG---LQGVKGHAGKRGILGDPGHQGKPGPKGD 215
             PG + G  G++        PPG KG  G   +  VKGH G+RG  G PG  G+PG  G 
Sbjct: 537  PPG-LPGKHGASG-------PPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGR 588

Query: 216  VGASGEQGIPGPPGPQ-----GIRGYPGMAGPKGETGP-----HGYKGMVGAIGATGPPG 265
             G +GE+G PGPPG       G +G+PG  GP G+ GP      G+ G  G  G  G PG
Sbjct: 589  DGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPG 648

Query: 266  EEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAG 325
              G RGP G  G+KGD  S  +  P G  GP G  GPPG  G  G  G PG+ GS G  G
Sbjct: 649  HPGVRGPDGLKGQKGDTISCNVTYP-GRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKG 707

Query: 326  QPGSPGHQGLAGVPGQPGTKGGPGDQGE--------PGPQGLPGFSGPPGKEGEP----- 372
            +PG+PG   + G PG  G  G PG  GE        PGP G PG +G  G  G+P     
Sbjct: 708  RPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHL 767

Query: 373  GPRGEIGPQGIMGQKGDQGE------RGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVK 426
            GP G+ G  G+ G KG +G+       GP G PG  G +GPKG +G  G PG  G PG  
Sbjct: 768  GPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHS 827

Query: 427  GDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAP 486
             ++G+PG  G  G  G PG  G PG KG+ G+ G PGP G +G+ G PG PG  G  G P
Sbjct: 828  CERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLP 887

Query: 487  GV------QGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEV 540
            G+       G PGPPGP+G  G  G PG PG +G  G +           K    +    
Sbjct: 888  GIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCP------GAKGEPGEKGMS 941

Query: 541  AVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKR 600
             +   R   GA G +GPPG  G      ++G  G PGP G  G  G  G  G  G +G+R
Sbjct: 942  GLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRR 1001

Query: 601  GEKGDPGEVG--RGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPV 658
            GE G  G  G  RG PG  G PG PG PG PG    G  G  G PG PG+ G PG PGP 
Sbjct: 1002 GEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGS--TGLRGFIGFPGLPGDQGEPGSPGPP 1059

Query: 659  GLPG 662
            G  G
Sbjct: 1060 GFSG 1063



 Score =  481 bits (1238), Expect = e-136
 Identities = 329/867 (37%), Positives = 387/867 (44%), Gaps = 226/867 (26%)

Query: 26  RGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGL 85
           RGPPG  GP GP GP G PG  G+ G+ G  G  GPPG  G+ G  GP G  G PG+DG+
Sbjct: 64  RGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGLDGI 123

Query: 86  TGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGE------------- 132
            G  G PGP G PG+ G  G  G PG PG    G  GP GP+G PGE             
Sbjct: 124 PGHPGPPGPRGKPGMSGHNGSRGDPGFPGG--RGALGPGGPLGHPGEKGEKGNSVFILGA 181

Query: 133 -IGIRGPKGDP------------GPDGPSGPP------GPPGKPGRPGTIQGLEGSADFL 173
             GI+G +GDP            GP GP+G P      GPPG+PGRP    GL+G+    
Sbjct: 182 VKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRP----GLKGN---- 233

Query: 174 CPTNCPPGMKGPPGLQGVKG---------------HAGKRGILGDPGHQGKPGPKG---- 214
            P     G  G PG  G +G               + G++GI G PG  G PGP G    
Sbjct: 234 -PGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGE 292

Query: 215 -DVGASGEQGIPGPPGPQ---GIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPR 270
             +GA GE+GIPG PGP+   G  G PG  G KGE G  G  G+ G IG  G PG  G  
Sbjct: 293 SGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHP 352

Query: 271 GPPG-----RAGEKGDEGSPGIRGPQGITGPKGATGPPGINGK--------------DGT 311
           GPPG         KG  G PG  G  G TG  G  GPPG+ G+               G 
Sbjct: 353 GPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGF 412

Query: 312 PGTPGMKGSAGQAGQ----PGSPGHQGLAGVPGQPGTKGGPGDQ------GEPGPQGLPG 361
           PG PG+ G AG  G+    PG PG  G  G+PG PG +G PG        G PGPQG+ G
Sbjct: 413 PGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKG 472

Query: 362 FSGPPGKEG-------------EPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPK 408
             GPPG  G             EPGP G  GP G+ G++G +G+ G  G  G +G  GP 
Sbjct: 473 KVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPP 532

Query: 409 GEQGPPGIPGPQGLPG---------------VKGDKGSPGKTGPRGKVGDPGVAGLPGEK 453
           G +GPPG+PG  G  G               VKG KG  G  GP G  G PG  G  G  
Sbjct: 533 GAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHA 592

Query: 454 GEKGESGEP-----------------GPKGQQGVRGEP--GYPGPSGDAGAPGVQGYP-- 492
           GEKG+ G P                 GP G+ G  G P  G+PGP G+ G PGV G+P  
Sbjct: 593 GEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGV 652

Query: 493 ------------------------------GPPGPRGLAGNRGVPGQPGRQGVEGRDATD 522
                                         GPPGP+G  G +G PG  G  G +GR  T 
Sbjct: 653 RGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTP 712

Query: 523 QHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGY---------------- 566
                      +  + +     ++ +      +GPPGPPG PG                 
Sbjct: 713 GTAEIPGPPGFRGDMGDPGFGGEKGS----SPVGPPGPPGSPGVNGQKGIPGDPAFGHLG 768

Query: 567 -PGKQGPHGHP---GPRGVPGIVGAVGQ------IGNTGPKGKRGEKGDPGEVG------ 610
            PGK+G  G P   GPRG PG  GA G       +G  GPKG+ G  G PG  G      
Sbjct: 769 PPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSC 828

Query: 611 -RGHPGMPGPPGIPGLPGRPG-QAINGKDGDRGSP------GAPGEAGRPGLPGPVGLPG 662
            RG PG+PG PG+PG PG PG     G+ GD G P      G PG  GRPG  GP GLPG
Sbjct: 829 ERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPG 888

Query: 663 FCEPAACLGASAYASARLTEPGSIKGP 689
              P        +    L  P   KGP
Sbjct: 889 IPGP--------FGDDGLPGPPGPKGP 907



 Score =  464 bits (1193), Expect = e-130
 Identities = 327/818 (39%), Positives = 365/818 (44%), Gaps = 181/818 (22%)

Query: 19  VLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPD---- 74
           V  L  ++G  G+RG PG PG PG  G+ G  G  G PG+ G  GP G+PG+ G      
Sbjct: 176 VFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPG 235

Query: 75  -GPDGKPGIDGLTGAKGEPGP---------------MGIPGVKGQPGLPGPPGLPG---- 114
            G  G+ G  G  G +G PGP                GI G+ G  GLPGPPG  G    
Sbjct: 236 VGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGI 295

Query: 115 --------PGFAGPPGPPGP---------------VGLPGEIGIRGPKGDPGPDGPSGPP 151
                   PGF GP G PG                VG PG  G+ GPKGDPG  G  GPP
Sbjct: 296 GAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPP 355

Query: 152 -----------GPPGKPGRPGTI-----------QGLEGSADFLCPTNC-PPGMKGPPGL 188
                      GPPG PG PG              GL G     C     PPG +G PGL
Sbjct: 356 GVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGL 415

Query: 189 QGVKGHAGKRGILGD-PGHQGKPGPKGDVGASGEQGIPGP---------PGPQGIRGYPG 238
            G+ G AG  G     PG  GKPG  G  GA G QG+PG          PGPQGI+   G
Sbjct: 416 PGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIK---G 472

Query: 239 MAGPKGETGPHGYKGMVGAIGA-TGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPK 297
             GP G  GP G KG  G      GP G  GP G PGR G KGD G PG  G +G  GP 
Sbjct: 473 KVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPP 532

Query: 298 GATGPPGINGKDGTPGTPGMKGSAGQ---------------------AGQPGSPGHQGLA 336
           GA GPPG+ GK G  G PG KG+ G                       GQPGS G  G A
Sbjct: 533 GAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHA 592

Query: 337 GVPGQPGTKGG-----PGDQGEPGPQGLP-----------GFSGPPGKEGEPGPRGE--- 377
           G  G PG  G      PG +G PGP G P           GF GPPG+ G PG  G    
Sbjct: 593 GEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGV 652

Query: 378 IGPQGIMGQKGD-----------------QGERGPVGQPGPQGR---QGPKGEQGPPGIP 417
            GP G+ GQKGD                  G  GP G PGPQG     G  G +G PG P
Sbjct: 653 RGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTP 712

Query: 418 GP---QGLPGVKGDKGSPGKTGPRGK--VGDPGVAGLPGEKGEKGESGEP-----GPKGQ 467
           G     G PG +GD G PG  G +G   VG PG  G PG  G+KG  G+P     GP G+
Sbjct: 713 GTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGK 772

Query: 468 QGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVD 527
           +G+ G PG  GP GD G PG +G  G PG  GL G +G  G  G  GV G      H  +
Sbjct: 773 RGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPG---HSCE 829

Query: 528 VALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGP------PGYPGKQGPHGHPGPRGV 581
                +  Q           A G  G  G  GPPGP      PG PG+ G HG PG  G+
Sbjct: 830 RGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGI 889

Query: 582 PGIVGAVGQIGNTGPKGKRGEKGDPGEVG-RGHPGMPGPPGIPGLPGRPGQAINGKDGDR 640
           PG  G  G  G  GPKG RG  G PG  G RG PG  G PG  G PG  G  ++G  GDR
Sbjct: 890 PGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKG--MSGLPGDR 947

Query: 641 GSPGAPG---------------EAGRPGLPGPVGLPGF 663
           G  GA G               + G PG PGP G  GF
Sbjct: 948 GLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGF 985



 Score =  462 bits (1188), Expect = e-130
 Identities = 292/695 (42%), Positives = 340/695 (48%), Gaps = 120/695 (17%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGL- 85
            G PG+ G PG PG PG PG  G  GD GPPG AG  G  G PG+ G  GP G PGI G  
Sbjct: 834  GIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPF 893

Query: 86   --TGAKGEPGPMGIPGVKGQPGLPGPPGLPG----PGFAGPPGPPGPVGLPGEIGIRGPK 139
               G  G PGP G  G+ G PG PG  G PG    PG  G PG  G  GLPG+ G+RG K
Sbjct: 894  GDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAK 953

Query: 140  GDPGPDGPSG------PPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKG 193
            G  GP G  G        G PG+PG PG   G  G            G KG PG+QG +G
Sbjct: 954  GAIGPPGDEGEMAIISQKGTPGEPGPPGD-DGFPGER----------GDKGTPGMQGRRG 1002

Query: 194  HAGKRGILGDPG-HQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGE---TGPH 249
              G+    G PG H+G+PG KG  G  G  G PG  G +G  G+PG+ G +GE    GP 
Sbjct: 1003 EPGR---YGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPP 1059

Query: 250  GYKGMVGA-------------IGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGP 296
            G+ G+ GA              G  GP GE G  G PG  G  G++G PGI+GP+   G 
Sbjct: 1060 GFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPR---GS 1116

Query: 297  KGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGP 356
             G  GPPG +G  G PG  GM G  GQ G+ G PG +GL G PG PG  G  G  G PG 
Sbjct: 1117 PGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGL 1176

Query: 357  QGLPGFSGPPGKEG-----EPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQ 411
             GL G  G  G +G     + GP G +G  G+ G++GD G  G +  PGP+G++GP G  
Sbjct: 1177 NGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPG-ISPPGPRGKKGPPGPP 1235

Query: 412  GPPGIPGPQGL----------PGVKGDKGSPGKTGPRGKVGDPGVAG----LPGEKGEKG 457
            G  G PGP G           PG  GD+G PG  GPRG  G PG+ G    L GE G+ G
Sbjct: 1236 GSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCG 1295

Query: 458  ESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGL---AGNRGVPGQPGRQG 514
              G PGP G  G  G  G+PG  G  G  G  G+PGP GP G     G +G+PG PGR+ 
Sbjct: 1296 LPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRK- 1354

Query: 515  VEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPG----YPGKQ 570
                                               G  G+ GP G PGPP      P   
Sbjct: 1355 -----------------------------------GPTGLPGPRGEPGPPADVDDCPRIP 1379

Query: 571  GPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPG 630
            G  G PG RG  G +G  G  G +GP    G KG+PG  GR   G+ G PG PG PGR G
Sbjct: 1380 GLPGAPGMRGPEGAMGLPGMRGPSGP----GCKGEPGLDGR--RGVDGVPGSPGPPGRKG 1433

Query: 631  QAINGKDGDRGSPGAPGEAGRPGLP--GPVGLPGF 663
                G+DG  G PG PG  G PG    GP  L GF
Sbjct: 1434 D--TGEDGYPGGPGPPGPIGDPGPKGFGPGYLGGF 1466



 Score =  398 bits (1023), Expect = e-111
 Identities = 243/546 (44%), Positives = 280/546 (51%), Gaps = 76/546 (13%)

Query: 20   LALAQIRGPPGERGPPGP---PGPPGVPGSDGIDGDNGPPGKAGPPG-PKGEPGKAGPDG 75
            +A+   +G PGE GPPG    PG  G  G+ G+ G  G PG+ GPPG  +GEPG+ G  G
Sbjct: 965  MAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPG 1024

Query: 76   PDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPG-PGFAGPP----------GPP 124
            P G PG  G TG +G  G  G+PG +G+PG PGPPG  G  G  GP           GPP
Sbjct: 1025 PPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPP 1084

Query: 125  GPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKG 184
            GP G PG  G  G  G  G  G  G  GP G PGRPG                 PPG  G
Sbjct: 1085 GPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPG-----------------PPGSSG 1127

Query: 185  PPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKG 244
            PPG  G  G  G R   G PG  G PGP+   G  G+ GIPGPPG +G  G PG+     
Sbjct: 1128 PPGCPGDHGMPGLR---GQPGEMGDPGPR---GLQGDPGIPGPPGIKGPSGSPGL----- 1176

Query: 245  ETGPHGYKGMVGAIGATG--PPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGP 302
              G HG KG  G  GA+G    G  GP G PG  GE+GD GSPGI  P    GP+G  GP
Sbjct: 1177 -NGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPP----GPRGKKGP 1231

Query: 303  PGINGKDGTPGTPGMKGSA----------GQAGQPGSPGHQGLAGVPGQPGT----KGGP 348
            PG  G  G PG  G  G A          G  G PG  G +G  G PG PG+    +G P
Sbjct: 1232 PGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEP 1291

Query: 349  GDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPK 408
            GD G PGP G PG  GPPG +G PG  G+ G +G +G  G QG  G  G PG +G  GP 
Sbjct: 1292 GDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPP 1351

Query: 409  GEQGPPGIPGPQGLPG----------VKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGE 458
            G +GP G+PGP+G PG          + G  G+PG  GP G +G PG+ G P   G KGE
Sbjct: 1352 GRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRG-PSGPGCKGE 1410

Query: 459  SGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGV-PGQPGRQGVEG 517
             G  G +G  GV G PG PG  GD G  G  G PGPPGP G  G +G  PG  G   +  
Sbjct: 1411 PGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGFGPGYLGGFLLVL 1470

Query: 518  RDATDQ 523
               TDQ
Sbjct: 1471 HSQTDQ 1476



 Score =  394 bits (1012), Expect = e-109
 Identities = 251/621 (40%), Positives = 295/621 (47%), Gaps = 153/621 (24%)

Query: 26   RGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGE---PGKAGPDGPDGKPGI 82
            +G PG+ GPPGP G  G+PG  G  G +GPPG  G PGP G+   PG  GP GP G PG 
Sbjct: 854  KGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGF 913

Query: 83   DGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP-------------------------GF 117
             G  G +G+PG  G PG KG+PG  G  GLPG                          G 
Sbjct: 914  PGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGT 973

Query: 118  AGPPGPPGPVGLPGEIG------IRGPKGDPGPDGP----------SGPPGPPGKPGRPG 161
             G PGPPG  G PGE G      ++G +G+PG  GP           G PGPPG PG PG
Sbjct: 974  PGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPG 1033

Query: 162  TIQGLEGSADF--LCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPG-HQGKPGPKGD--- 215
            +  GL G   F  L      PG  GPPG  G+ G  G +G  GDP  H G PGPKG+   
Sbjct: 1034 ST-GLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGS 1092

Query: 216  ------VGASGEQGIPG---------------------------------------PPGP 230
                   GASGEQG+PG                                        PGP
Sbjct: 1093 PGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGP 1152

Query: 231  QGIRGYPGMAGPKGETGP---------HGYKGMVGAIGATG--PPGEEGPRGPPGRAGEK 279
            +G++G PG+ GP G  GP         HG KG  G  GA+G    G  GP G PG  GE+
Sbjct: 1153 RGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGER 1212

Query: 280  GDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSA----------GQAGQPGS 329
            GD GSPGI  P    GP+G  GPPG  G  G PG  G  G A          G  G PG 
Sbjct: 1213 GDPGSPGISPP----GPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGP 1268

Query: 330  PGHQGLAGVPGQPGT----KGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMG 385
             G +G  G PG PG+    +G PGD G PGP G PG  GPPG +G PG  G+ G +G +G
Sbjct: 1269 DGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVG 1328

Query: 386  QKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPG----------VKGDKGSPGKT 435
              G QG  G  G PG +G  GP G +GP G+PGP+G PG          + G  G+PG  
Sbjct: 1329 FPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMR 1388

Query: 436  GPRGKVGDPGVAG-----------LPGEKGEKGESGEPGPKGQQGVRGEPGYPG---PSG 481
            GP G +G PG+ G           L G +G  G  G PGP G++G  GE GYPG   P G
Sbjct: 1389 GPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPG 1448

Query: 482  DAGAPGVQGYPGPPGPRGLAG 502
              G PG +G+    GP  L G
Sbjct: 1449 PIGDPGPKGF----GPGYLGG 1465



 Score =  383 bits (984), Expect = e-106
 Identities = 259/666 (38%), Positives = 302/666 (45%), Gaps = 127/666 (19%)

Query: 112 LPGPGFAGPPGP------------PGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGR 159
           +P  G  GPPGP            PGP+GL GE G+RG +G PG  G  G  GP G PG 
Sbjct: 58  VPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGF 117

Query: 160 PGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGAS 219
           PG + G+ G      P    PGM G  G +G  G  G RG LG  G  G PG KG+ G S
Sbjct: 118 PG-LDGIPGHPGPPGPRG-KPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNS 175

Query: 220 --------------GEQGIP---------GPPGPQGIRGYPGMAGPKGETGPHGYKGM-- 254
                         G+ G+P         GP GP G  G PG+ GP G+ G  G KG   
Sbjct: 176 VFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPG 235

Query: 255 VGAIGATGPPGEEGPRGPPGRA------------GEKGDEGSPGIRGPQGITGPKGATGP 302
           VG  G  G PGE G +G PG              GEKG +G PG+ G  G  G KG +G 
Sbjct: 236 VGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESG- 294

Query: 303 PGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQP------GTKGGPGDQGEPGP 356
            G  G+ G PG PG +G  G  G PG PG +G  G+ G P      G KG PG++G PGP
Sbjct: 295 IGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGP 354

Query: 357 QGL-----------PGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQ-----GERGPVGQPG 400
            G+           PG  G PG+ GE G  G  GP G++G+ G+      G  GP G PG
Sbjct: 355 PGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPG 414

Query: 401 -------------PQGRQGPKGEQGPPGIPGPQGLPGVKGDK------GSPGKTGPRGKV 441
                        P    G  G+ G PG+PG  GL G+ G        G+PG  G +GKV
Sbjct: 415 LPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKV 474

Query: 442 GDPGVAGLPGEKGEKGESG-EPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGL 500
           G PG  G  GEKG +G    EPGP G  G  G PG  G  GD G PG  G  G PGP G 
Sbjct: 475 GPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGA 534

Query: 501 AGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGP 560
            G  G+PG+ G  G  G       +V   +K                  G  G  GP GP
Sbjct: 535 EGPPGLPGKHGASGPPGNKGAKGDMVVSRVK------------------GHKGERGPDGP 576

Query: 561 PGPPGYPGKQGPHGHPGPRGVPGIVG-----AVGQIGNTGPKGKRGEKGDPGEVGRGHPG 615
           PG PG PG  G  GH G +G PG  G       G  G  GP G  G+ G  G  G G PG
Sbjct: 577 PGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPG 636

Query: 616 MPGPPGIPGLPGRPGQAINGKDGDRGSPG--------APGEAGRPGLPGPVGLPGFCEPA 667
            PG  G PG+PG PG  + G DG +G  G         PG  G PG  GP G  GF  P 
Sbjct: 637 PPGERGHPGVPGHPG--VRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQ 694

Query: 668 ACLGAS 673
              G S
Sbjct: 695 GAPGLS 700



 Score =  340 bits (872), Expect = 3e-93
 Identities = 226/593 (38%), Positives = 282/593 (47%), Gaps = 98/593 (16%)

Query: 161 GTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGH------QGKPGPKG 214
           G   G + S     P     G  GPPG QG  G  G  G +G  G       +G PG  G
Sbjct: 45  GPCGGRDCSVCHCVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAG 104

Query: 215 DVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPG 274
           D G  G  G+PG PG  GI G+PG  GP+G+ G  G+ G  G  G  G  G  GP GP G
Sbjct: 105 DKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLG 164

Query: 275 RAGEKGDEGSPG--IRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGH 332
             GEKG++G+    +   +GI G +G  G PG+      PG+ G  G AG  G PG PG 
Sbjct: 165 HPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGL------PGSWGAGGPAGPTGYPGEPGL 218

Query: 333 QGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGI---MGQKGD 389
            G  G PG+PG KG PG     G +G  G  G  G++G PGP   + P       G+KG 
Sbjct: 219 VGPPGQPGRPGLKGNPG----VGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGI 274

Query: 390 QGERGPVGQPGPQGRQ-----GPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDP 444
           +G  G VG PGP GR+     G KGE+G PG PGP+G PG  G  G PG  G  G VGDP
Sbjct: 275 KGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDP 334

Query: 445 GVAGLPGEKGEKGESGEPGPKG--------QQGVRGEPGYPGPSGDA------GAPGVQG 490
           G+ GL G KG+ G  G PGP G         +G  G+PG+PG  G+       G PG+ G
Sbjct: 335 GLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLG 394

Query: 491 YP--------GPPGPRGL-------------------------AGNRGVPGQPGRQGVEG 517
            P        GPPGP+G                           G+ G+PG PG QG+ G
Sbjct: 395 RPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPG 454

Query: 518 RDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMM----GPPGPPGPPGYPGKQ--- 570
                  + +   + ++ ++        +   G  G+     GP GPPGPPG PG+Q   
Sbjct: 455 SSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSK 514

Query: 571 ---------GPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGR--GHPGMPGP 619
                    G  G PGP G  G  G  G+ G +GP G +G KGD   V R  GH G  GP
Sbjct: 515 GDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDM-VVSRVKGHKGERGP 573

Query: 620 PGIPGLPGRPG-QAINGKDGDRGSPGAPGE-----AGRPGLPGPVGLPGFCEP 666
            G PG PG+PG    +G  G++G PG PG+      G  G PGP+G PG   P
Sbjct: 574 DGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGP 626



 Score =  312 bits (800), Expect = 6e-85
 Identities = 187/433 (43%), Positives = 223/433 (51%), Gaps = 74/433 (17%)

Query: 26   RGPPGERGPP----GPPGP------PGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDG 75
            RGP G +G P    GPPGP      PG PG  G  G+ G PG  GP G  G PG  G  G
Sbjct: 1068 RGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSG 1127

Query: 76   PDGKPGIDGLTGAKGEPGPMGIPG---VKGQPGLPGPPGLPGPGFAGPPG---------- 122
            P G PG  G+ G +G+PG MG PG   ++G PG+PGPPG+ GP  +G PG          
Sbjct: 1128 PPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGP--SGSPGLNGLHGLKGQ 1185

Query: 123  -------------PPGPVGLPGEIGIRGPKGD-----PGPDGPSGPPGPPGKPGRPGTIQ 164
                         PPGPVG+PG  G RG  G      PGP G  GPPGPPG  G PG   
Sbjct: 1186 KGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGP-A 1244

Query: 165  GLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPG-HQGKPGPKGDVGASGEQG 223
            G  G A    P   PPG +GPPG  G +G  G  G+ G     +G+P   GD G  G  G
Sbjct: 1245 GATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEP---GDCGLPGPPG 1301

Query: 224  IPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEG 283
             PGPPGP G +G+PG  G  G+ GP G+ G  G  G  GPPGE+G  GPPGR      +G
Sbjct: 1302 PPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGR------KG 1355

Query: 284  SPGIRGPQGITGP----------KGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQ 333
              G+ GP+G  GP           G  G PG+ G +G  G PGM+G +G  G  G PG  
Sbjct: 1356 PTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSG-PGCKGEPGLD 1414

Query: 334  GLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMG-------Q 386
            G  GV G PG+ G PG +G+ G  G PG  GPPG  G+PGP+G  GP G +G        
Sbjct: 1415 GRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKG-FGP-GYLGGFLLVLHS 1472

Query: 387  KGDQGERGPVGQP 399
            + DQ    P+G P
Sbjct: 1473 QTDQEPTCPLGMP 1485



 Score =  236 bits (601), Expect = 7e-62
 Identities = 162/403 (40%), Positives = 188/403 (46%), Gaps = 80/403 (19%)

Query: 341 QPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPG 400
           + G++G PG  G  GP G  G  GP G  GE G RG+ GP G  G KGD   +GP G PG
Sbjct: 60  EKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGD---KGPTGVPG 116

Query: 401 PQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESG 460
             G  G  G  GPPG  G  G+ G  G +G PG  G RG +G  G  G PGEKGEKG S 
Sbjct: 117 FPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSV 176

Query: 461 --EPGPKGQQGVRGEPGYP------------GPSGDAGAPGVQGYPGPPGPRGLAGNRGV 506
                 KG QG RG+PG P            GP+G  G PG+ G PG PG  GL GN GV
Sbjct: 177 FILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGV 236

Query: 507 --------PGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPP 558
                   PG+ G+QG  G              +L E         ++   G  GM+G P
Sbjct: 237 GVKGQMGDPGEVGQQGSPGP------------TLLVEPPDFCLYKGEKGIKGIPGMVGLP 284

Query: 559 GPPGP--------------PGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKG 604
           GPPG               PG+PG +G  G  G  G PG+ G +G +G+ G  G  G KG
Sbjct: 285 GPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKG 344

Query: 605 DPGEVGRGHPGMP-----------GPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRP- 652
           DPG   RGHPG P           GPPG PG PGR G+      GD G PG PG  GRP 
Sbjct: 345 DPG--NRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGET-----GDVGPPGPPGLLGRPG 397

Query: 653 -------GLPGP---VGLPGFCEPAACLGASAYASARLTEPGS 685
                  G PGP    GLPG    A   G    A  +  +PGS
Sbjct: 398 EACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGS 440


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  506 bits (1303), Expect = e-143
 Identities = 330/827 (39%), Positives = 385/827 (46%), Gaps = 174/827 (21%)

Query: 22   LAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGP--PGPKGEPGKAGPDGPDGK 79
            L  + G PG +GP GPPGP G  G  G  G  G P   GP   GPKGE G  GP GP G 
Sbjct: 1508 LPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGA 1567

Query: 80   PGID--------------------------GLTGAKGEPGPMGIPGVKGQPGLPGPPGLP 113
             G+                           GLTG  G PG  G PG KG PG PGPPG  
Sbjct: 1568 TGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPV 1627

Query: 114  GP-------GFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGL 166
            GP       G  G  GPPG  GLPG+ G RG +G PG  GP G  G  G PG  G   G 
Sbjct: 1628 GPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGR-NGS 1686

Query: 167  EGSADFLCPTNCPPGMKGPPGLQGVKGH-------AGKRGILGDPGHQGKPGPKGD---V 216
             GS+        P G +G PG  G  G        A ++G  GD G +G  GPKGD    
Sbjct: 1687 PGSSG-------PKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLP 1739

Query: 217  GASGEQGIP---GPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPP 273
            GA GE+GI    GPPGPQG  G  G AG KG+ GP G  G  G  G  G  G  GP G  
Sbjct: 1740 GAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAA 1799

Query: 274  GRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQ 333
            G+AG+ G +G PG+RG QG+ GP G  G PG  G+DG PG  G  G  G  G+ G  G +
Sbjct: 1800 GKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEK 1859

Query: 334  GLAGVPGQPGTKGGPGDQGEP---GPQGLPGFSGP--------PGKEGEPGPRGEIGPQG 382
            G +G  G+ G  G  G++G P   GPQG PG  GP        PG  G  GP+G+ G  G
Sbjct: 1860 GDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETG 1919

Query: 383  IMGQKGDQGERGPVGQPG------------------------------------PQGRQG 406
              G++G  GERG  G+PG                                    P+ R+G
Sbjct: 1920 SKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRG 1979

Query: 407  PK---GEQGPPGIPGPQGLP---GVKGDKGSPGKTGP----------------RGKVGDP 444
            PK   GEQGPPG  GP G P   G+KGD+G PG  GP                 G+ G P
Sbjct: 1980 PKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKP 2039

Query: 445  GVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPR------ 498
            G+ GLPG  G  GE+G PG +G++G +GE G  G  G  G PG  G PGPPGP+      
Sbjct: 2040 GIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEP 2099

Query: 499  --GLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMG 556
              GL+G +G PG  G +G  G +       D  +  ++    E      R   G  G+ G
Sbjct: 2100 GPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGE---PGPRGQDGNPGLPG 2156

Query: 557  PPGPPGPPGYPGKQGPHGHPGP---RGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG--- 610
              G  GP G PG QGP G PGP    G PG  GA G  G  GP+G  G KG+PGE G   
Sbjct: 2157 ERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPG 2216

Query: 611  ------RGHPGMPGPPGIPGL------PGRPGQ-------------AINGKDGDRGSPGA 645
                   G  G+PGPPG  GL      PG PGQ               +GKDGDRGSPG 
Sbjct: 2217 RGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGV 2276

Query: 646  PGEAGRPGLPGPVGLPGFCEPAACLGASAY----ASARLTEPGSIKG 688
            PG    PGLPGPVG  G   P    G +      A      PG + G
Sbjct: 2277 PGS---PGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAG 2320



 Score =  504 bits (1297), Expect = e-142
 Identities = 308/685 (44%), Positives = 353/685 (51%), Gaps = 89/685 (12%)

Query: 26   RGPPGE---RGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGI 82
            +G PGE   RG  GPPG PG+PG  G  G  GPPG A   G +G PG       DG+PG 
Sbjct: 1256 KGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGA------DGRPGS 1309

Query: 83   DGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP----GFAGPPGPPGPV------GLPGE 132
             G  G    PG  G PG+KG PGLPGP G PG     G  G PG PG V      GLPG 
Sbjct: 1310 PGRAG---NPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGR 1366

Query: 133  IGIRGPKGDPGPDGPSGPPGPPGKPGRPGT-IQGLEGSADFLCPTN------CP-----P 180
             G  GP G PGP GP G PGP G PG PGT ++G +G      P         P     P
Sbjct: 1367 KGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLP 1426

Query: 181  GMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPP---GPQGIRGYP 237
            G+ G PG QG  G  GK+G  GD    G PG  G  G+ GEQG  GPP   GP+G RG+P
Sbjct: 1427 GLPGSPGPQGPVGPPGKKGEKGD-SEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFP 1485

Query: 238  ---GMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPP---GRAGEKGDEGSPG----- 286
               G AG KGE GP G  G  G  G  G PG +GP GPP   GR GEKG+ G PG     
Sbjct: 1486 GPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVV 1545

Query: 287  ---IRGPQGITGPKGATGPPGINGKDGTPGTPG--MKGSAGQAGQPGSPGHQGLAGVPGQ 341
               + GP+G  G  G  GP G  G  G  G PG  + G  G  G PG  G  GL G  G 
Sbjct: 1546 GPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGP 1605

Query: 342  PGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGP 401
            PG  G PG++G+PG  G PG  GP G++GE G +G+ GP G  G  G  GERG  G PG 
Sbjct: 1606 PGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGV 1665

Query: 402  QGRQGPKGEQGPPGIPGPQGLP---GVKGDKGSPGKTGPRGKVGDPGV-AGLPGEKGEKG 457
            +G  G KG+QG PG  G  G P   G KGD+G PG  GP G++ D G  A   GE G++G
Sbjct: 1666 RGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRG 1725

Query: 458  ESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEG 517
            + G  GPKG  G+ G PG  G  G  G PG QG PG  GP G  G+RG PG  GR G++G
Sbjct: 1726 QEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDG 1785

Query: 518  RDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPG 577
            +                               G  G  G  G PG  G PG +G  G PG
Sbjct: 1786 KPGA------------------------AGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPG 1821

Query: 578  PRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKD 637
            P G PG+ G  G+ G  G  GK GE GDPGE GR      G  G  G  GR G+  +G  
Sbjct: 1822 PSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGR-----KGEKGDSGASGREGR--DGPK 1874

Query: 638  GDRGSPGAPGEAGRPGLPGPVGLPG 662
            G+RG+PG  G  G PGLPGPVG PG
Sbjct: 1875 GERGAPGILGPQGPPGLPGPVGPPG 1899



 Score =  503 bits (1294), Expect = e-142
 Identities = 313/729 (42%), Positives = 367/729 (50%), Gaps = 101/729 (13%)

Query: 27   GPPGERGPPGPPGPPGVPGS-----DGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPG 81
            GPPG  G PGPPGPPG   S      G+ G+ GPPG  G    KGEPG  G  GP G  G
Sbjct: 2076 GPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGA---KGEPGSNGDQGPKGDRG 2132

Query: 82   IDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP----GFAGPPGPPGPVGL---PGEIG 134
            + G+ G +GEPGP G     G PGLPG  G+ GP    G  GP GPPGPVG    PG  G
Sbjct: 2133 VPGIKGDRGEPGPRG---QDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPG 2189

Query: 135  IRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGH 194
              G  G  GP GPSG  G PG+ G PG  +GL G      PT    G+ GPPG  G+ G 
Sbjct: 2190 APGLAGPAGPQGPSGLKGEPGETGPPG--RGLTG------PTGAV-GLPGPPGPSGLVGP 2240

Query: 195  AGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKG- 253
             G  G+ G  G  GKPG  G  GASG+ G  G PG  G  G PG  GPKGE GP G  G 
Sbjct: 2241 QGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQ 2300

Query: 254  ---------------------MVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQG 292
                                 +VG  GA G  G  GPRG  G AG  G+ G PG  G +G
Sbjct: 2301 AVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKG 2360

Query: 293  ITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQG 352
              GPKG  G PG+ G  G+PG PG  G  G  G PG PG  G+ G PGQ G +G   + G
Sbjct: 2361 APGPKGFKGDPGV-GVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRG---EMG 2416

Query: 353  EPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQG 412
            +PGP G  G +GPPG+EG PGP G  GP G +G  G  G +G  G PG  G  GP+GE+G
Sbjct: 2417 QPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGV-GLPGPRGERG 2475

Query: 413  PPGIPGPQGLPGVKGDKG---SPGKTGPRGKVGDPGVAGLPGEKGE-------------K 456
             PGI G  G PG +G +G    PG  G RG+ GD G AGL G+KG+             K
Sbjct: 2476 EPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAK 2535

Query: 457  GESGEPGP------KGQQGVRGEPG------YPGPSGDAGAPGVQGYPGPPGPRGLAGNR 504
            G+ GE GP      KG +G  G+PG       PG  G AG PG++G  GP G  G AG  
Sbjct: 2536 GDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIP 2595

Query: 505  GVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPP 564
            G PG PG+ GV G       +  +  + L+ +             G  G  GPPG PG  
Sbjct: 2596 GDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLA 2655

Query: 565  GYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-RGHPGM---PGPP 620
            G+ G+ G  G PG  G PG  G +G  G+ G  G+ G KGD GE G RG PG+   PGP 
Sbjct: 2656 GHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPS 2715

Query: 621  GIPGLPGRPG----------QAINGKDGDRGSPG-----APGEAGRPGLPGPVGLPGFCE 665
            G  G  G PG          + + G+ G+RG PG     APG  G PG  G  G PG   
Sbjct: 2716 GNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAG 2775

Query: 666  PAACLGASA 674
            P    G +A
Sbjct: 2776 PRGEKGEAA 2784



 Score =  499 bits (1284), Expect = e-141
 Identities = 317/813 (38%), Positives = 390/813 (47%), Gaps = 185/813 (22%)

Query: 25   IRGPPGERGPPGPPGP---------------------PGVPGSDGIDGDNGPPGKAGP-- 61
            ++G PG  GP G PG                      PG+PG  G  G +GPPG  GP  
Sbjct: 1324 LKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLG 1383

Query: 62   -PGPKGEP--------------GKAGPDGP------DGKPGIDGLTGAKGEPGPMGIPGV 100
             PGP+G P              G+ GP GP       G+PG+ GL G+ G  GP+G PG 
Sbjct: 1384 DPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGK 1443

Query: 101  KGQ--------PGLPGPPGLPG-------PGFAGPPGP---PGPVGLPGEIGIRGPKGD- 141
            KG+        PGLPG PG PG       PG  GP G    PGP+G  GE G RGP G  
Sbjct: 1444 KGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPA 1503

Query: 142  -----------PGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPP-------GMK 183
                       PG  GP GPPGP G+ G  G   G  G    + P    P       G  
Sbjct: 1504 GSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGE-PGRPGDPAVVGPAVAGPKGEKGDVGPA 1562

Query: 184  GPPGLQGVKGHAGKRGIL--GDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAG 241
            GP G  GV+G  G  G++  GDPG +G PG +G +G +G  G PG  GP G +G PG  G
Sbjct: 1563 GPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPG 1622

Query: 242  PKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATG 301
            P G  GP G  G VG  G  GPPG+    G PG+AGE+G  G+PG+RGP    G KG  G
Sbjct: 1623 PPGPVGPRGRDGEVGEKGDEGPPGDP---GLPGKAGERGLRGAPGVRGP---VGEKGDQG 1676

Query: 302  PPGINGKDGTPGTPGMKGSAGQAGQPGSPGH-------------------------QGLA 336
             PG +G++G+PG+ G KG  G+ G PG PG                          +G  
Sbjct: 1677 DPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDP 1736

Query: 337  GVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGP- 395
            G+PG PG +G  G +G PGPQG PG  GP G++G+ GP G  G  G+ G+ G  G  GP 
Sbjct: 1737 GLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPN 1796

Query: 396  -----VGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLP 450
                  G PG  G  G +GEQG PG  GP GLPG  G+ G PG  G  G+ GDPG  G  
Sbjct: 1797 GAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRK 1856

Query: 451  GEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGV-----QGYP------GPPGPRG 499
            GEKG+ G SG  G  G +G RG PG  GP G  G PG      QG+P      GP G RG
Sbjct: 1857 GEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRG 1916

Query: 500  LAGNRGVPGQPGRQGVEGRDATDQHIVDV---------ALKMLQEQLAEVAVS------A 544
              G++G  G PG +G+ G   +  ++  +         AL+ + E   E + S       
Sbjct: 1917 ETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPER 1976

Query: 545  KREALGAVGMMGPPGPPGPPGYPGK---QGPHGHPGPRGVPGI----------------- 584
            +R   G  G  GPPG  GP G+PG+   +G  G PGP+G PG+                 
Sbjct: 1977 RRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEP 2036

Query: 585  -----------VGAVGQIGNTGPKGKRGEKGDPGEVGR-GHPGMPGPPGIPGLPG----- 627
                        G VG+ G  G +G+RGEKG+ GE GR G PG+PG PG PG PG     
Sbjct: 2037 GKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSV 2096

Query: 628  -RPGQAINGKDGDRGSPGAPGEAGRPGLPGPVG 659
              PG  ++G+ G  G  GA GE G  G  GP G
Sbjct: 2097 DEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKG 2129



 Score =  494 bits (1271), Expect = e-139
 Identities = 312/755 (41%), Positives = 365/755 (48%), Gaps = 117/755 (15%)

Query: 26   RGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPG----PKGEPGKAGPDGPDGKPG 81
            +G  GE+GPPG  GP G PG  G+ GD G PG  GPPG     +G PG +G  G  GKPG
Sbjct: 1981 KGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPG 2040

Query: 82   IDGLTGAKGEPGPMGIPGVKGQ------------------PGLPGPPGLPGP-------- 115
            I GL G  G  G  G PG +G+                  PG PGPPG PGP        
Sbjct: 2041 IPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPG 2100

Query: 116  ----GFAGPPGPPGPVGLPGEIGIRGPKGD---PGPDGPSGPPGPPGKPGRPGT-----I 163
                G  GPPG  G  G PG  G +GPKGD   PG  G  G PGP G+ G PG      +
Sbjct: 2101 PGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGM 2160

Query: 164  QGLEGSADFLCPTNCP--------PGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGD 215
             G EG      P   P        PG  G PGL G  G  G  G+ G+PG  G PG +G 
Sbjct: 2161 AGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPG-RGL 2219

Query: 216  VGASGEQGIPGPPGPQGI---RGYPGMAGPKGETGPHGYKGMVGAIG------ATGPPGE 266
             G +G  G+PGPPGP G+   +G PG+ G  GETG  G  G  GA G      + G PG 
Sbjct: 2220 TGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGS 2279

Query: 267  EGPRGPPGRAGEKGDEGSPG--IRGPQGITGPKGA--------TGPPGINGKDGTPGTPG 316
             G  GP G  GE G  G+PG  + G  G  G KGA         G PG  G  G PG  G
Sbjct: 2280 PGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRG 2339

Query: 317  MKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPG-----DQGEPGPQGLPGFSGPPGKEGE 371
             KG AG+AG+PG PG  G  G PG  G KG PG       G PGP G+ G  G PG  G 
Sbjct: 2340 EKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGA 2399

Query: 372  PGP---RGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGD 428
            PG     G+ GP+G MGQ G  GERG  G PG +G  GP G  GPPG  GP G  G+KGD
Sbjct: 2400 PGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGD 2459

Query: 429  KGSPGK--TGPRGKVGDPGVAG---LPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDA 483
            KG PG    GPRG+ G+PG+ G    PG++G +G +G PG +G++G +G+ G  G  GD 
Sbjct: 2460 KGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDK 2519

Query: 484  GAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVS 543
            G   V    GPPGPRG  G+ G  G  G  G +G    +    D   K          + 
Sbjct: 2520 GDSAV--ILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLP 2577

Query: 544  AKREALGAVGMMGPPGPPGPPGYPGK---------QGPHGHPGPRGVPGIVGAVGQIGNT 594
              R  LG  G  G  G PG PG PGK         +G  G  GPRG+ G  G  G  G  
Sbjct: 2578 GLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLD 2637

Query: 595  GPKGKRGEKGDPGEVG-RGHPGMPGPPGIPGLPGRPGQ-------------------AIN 634
            G KG +GE G PG  G  GH G  G PG+PG  G PG+                      
Sbjct: 2638 GEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQ 2697

Query: 635  GKDGDRGSPGA---PGEAGRPGLPGPVGLPGFCEP 666
            G+ G+RG+PG    PG +G  G  GP G PG   P
Sbjct: 2698 GEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGP 2732



 Score =  493 bits (1268), Expect = e-139
 Identities = 314/812 (38%), Positives = 366/812 (45%), Gaps = 196/812 (24%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
            G  GE+G  GPPG PG+PG  G  G  G PG  GP G KG+ G  G DG +G PG  G  
Sbjct: 1634 GEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPK 1693

Query: 87   GAKGEPGPMGIPG-------------------------VKGQPGLPGPPGLPG-PGFAGP 120
            G +GEPGP G PG                          KG PGLPG PG  G  GF GP
Sbjct: 1694 GDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGP 1753

Query: 121  PGPPGPVGLPGEIGIRGPKGDPGPDG------------PSGPPGPPGKPGRPGT--IQGL 166
            PGP G  G+ G  G +G +G PG DG            PSGP G  GK G PG   + GL
Sbjct: 1754 PGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGL 1813

Query: 167  EGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQG--- 223
             G      P+  PPG+ G PG  G  G  GK G  GDPG  G+ G KGD GASG +G   
Sbjct: 1814 RGEQGLPGPSG-PPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDG 1872

Query: 224  ------------------IPGPPGP--QGIRGYPGMAGPK---GET---------GPHGY 251
                              +PGP GP  QG  G PG  GPK   GET         G  G 
Sbjct: 1873 PKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGL 1932

Query: 252  KGMVGAI---------------------------------------------GATGPPGE 266
            +G  G++                                             G  GPPG+
Sbjct: 1933 RGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGK 1992

Query: 267  EGPRGPPGRAGEKGDEGSPGIRGPQGIT-GPKGATGPPGINGKDGTPGTPGMKGSAGQAG 325
            EGP G PG  G KGD G PG +GP G+  G +G  GP G+ G+ G PG PG+ G AG  G
Sbjct: 1993 EGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVG 2052

Query: 326  QPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMG 385
            + G PG +G      + G KG  G+QG  GP GLPG  GPPG  G      E GP G+ G
Sbjct: 2053 EAGRPGERG------ERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGP-GLSG 2105

Query: 386  QKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPG 445
            ++G  G +G  G+PG  G QGPKG++G PGI G +G PG +G  G+PG  G RG  G  G
Sbjct: 2106 EQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEG 2165

Query: 446  VAGL---------------PGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDA--GAPGV 488
              GL               PG  G  G +G  GP+G  G++GEPG  GP G    G  G 
Sbjct: 2166 KPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGA 2225

Query: 489  QGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREA 548
             G PGPPGP GL G +G PG PG+ G  G+                          +  A
Sbjct: 2226 VGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAP---------------------GRDGA 2264

Query: 549  LGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPG----------------------IVG 586
             G  G  G PG PG PG PG  GP G PGP G PG                      +VG
Sbjct: 2265 SGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVG 2324

Query: 587  AVGQIGNTGPKGKRGEKGDPGEVGR----GHPGMPGPPGIPGLPGRPGQAINGKDGDRGS 642
              G  G+ G  G RGEKG+ G  G     G  G  G PG  G  G PG  + G  G  G 
Sbjct: 2325 EPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGP 2384

Query: 643  PGAPGEAGRPGLPGP---VGLPGFCEPAACLG 671
            PG  G+ G PGLPG    VG PG   P   +G
Sbjct: 2385 PGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMG 2416



 Score =  488 bits (1257), Expect = e-138
 Identities = 303/769 (39%), Positives = 354/769 (46%), Gaps = 158/769 (20%)

Query: 25   IRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGP-------------KGEPGKA 71
            +RGP GE+G  G PG  G  GS G  G  G  G+ GPPGP             KGEPG  
Sbjct: 1665 VRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDR 1724

Query: 72   GPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPG 131
            G +GP G  G  GL GA   PG  GI G +G PG  G PG+ GP  AG  G  GP GL G
Sbjct: 1725 GQEGPRGPKGDPGLPGA---PGERGIEGFRGPPGPQGDPGVRGP--AGEKGDRGPPGLDG 1779

Query: 132  EIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGV 191
              G+ G  G  GP GP+G  G  G PGR G + GL G      P+  PPG+ G PG  G 
Sbjct: 1780 RSGLDGKPGAAGPSGPNGAAGKAGDPGRDG-LPGLRGEQGLPGPSG-PPGLPGKPGEDGK 1837

Query: 192  KGHAGKRGILGDPGHQGKPGPKGDVGAS---------GEQGIPGPPGPQGIRGYPGMAGP 242
             G  GK G  GDPG  G+ G KGD GAS         GE+G PG  GPQG  G PG  GP
Sbjct: 1838 PGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGP 1897

Query: 243  KGE--------TGPHGYKGMVGAIGATGPPGEEGPRGPPGRA------------------ 276
             G+        TGP G +G  G+ G  G PGE G RG PG                    
Sbjct: 1898 PGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALR 1957

Query: 277  ------------------------GEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTP 312
                                    G+ G++G PG  GP G  G +G  G  G  G  G P
Sbjct: 1958 EIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPP 2017

Query: 313  -------GTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGP 365
                   G PG  G AG+ G+PG PG  G AG  G+ G  G  G++GE G +G  G  GP
Sbjct: 2018 GLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGP 2077

Query: 366  PGKEGEPGPRGEIGPQ--------GIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIP 417
            PG  G PGP G  GP+        G+ G++G  G +G  G+PG  G QGPKG++G PGI 
Sbjct: 2078 PGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIK 2137

Query: 418  GPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGL---------------PGEKGEKGESGEP 462
            G +G PG +G  G+PG  G RG  G  G  GL               PG  G  G +G  
Sbjct: 2138 GDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPA 2197

Query: 463  GPKGQQGVRGEPGYPGPSGD--AGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDA 520
            GP+G  G++GEPG  GP G    G  G  G PGPPGP GL G +G PG PG+ G  G+  
Sbjct: 2198 GPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKP- 2256

Query: 521  TDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRG 580
                                    +  A G  G  G PG PG PG PG  GP G PGP G
Sbjct: 2257 --------------------GAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTG 2296

Query: 581  VPG----------------------IVGAVGQIGNTGPKGKRGEKGDPGEVGR----GHP 614
             PG                      +VG  G  G+ G  G RGEKG+ G  G     G  
Sbjct: 2297 APGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGED 2356

Query: 615  GMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGF 663
            G  G PG  G  G PG  + G  G  G PG  G+ G PGLPG  G+ GF
Sbjct: 2357 GQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGF 2405



 Score =  483 bits (1243), Expect = e-136
 Identities = 315/789 (39%), Positives = 366/789 (46%), Gaps = 162/789 (20%)

Query: 22   LAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPG 81
            L  +RG  G  GP GPPG PG PG DG  G N   GK G PG  GE G+ G  G  G  G
Sbjct: 1810 LPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLN---GKNGEPGDPGEDGRKGEKGDSGASG 1866

Query: 82   IDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGP------------VGL 129
             +G  G KGE G  GI G +G PGLPGP G PG GF G PG  GP             GL
Sbjct: 1867 REGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGL 1926

Query: 130  PGEIGI---------------------------------------------RGPKGDPGP 144
            PGE G+                                             RGPKGD G 
Sbjct: 1927 PGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGE 1986

Query: 145  DGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGI---- 200
             GP G  GP G PG  G ++G  G      P     G +GPPG  G+ G  GK GI    
Sbjct: 1987 QGPPGKEGPIGFPGERG-LKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLP 2045

Query: 201  -----LGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPK-----------G 244
                 +G+ G  G+ G +G+ G  GEQG  GPPG  G  G PG  GPK           G
Sbjct: 2046 GRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSG 2105

Query: 245  ETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPG 304
            E GP G KG  G  G+ G  G +G RG PG  G++G+ G  G  G  G+ G +G  GP G
Sbjct: 2106 EQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEG 2165

Query: 305  INGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSG 364
              G  G  G PG  G  G  G PG+PG  G AG  G  G KG PG+ G PG +GL G +G
Sbjct: 2166 KPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPG-RGLTGPTG 2224

Query: 365  PPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPG 424
              G  G PGP G +GPQG  G  G  GE G  G PG  G  G  G++G PG+PG  GLPG
Sbjct: 2225 AVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPG 2284

Query: 425  VKGDKGSPGKTGPRGK----------------------VGDPGV---AGLPGEKGEKGES 459
              G KG PG TG  G+                      VG+PG     GLPG +GEKGE+
Sbjct: 2285 PVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEA 2344

Query: 460  GEPGPKGQQGVRGEPGYPGPSGDAGAP--GVQGYPGPPGPRGLAGNRGVPGQPGRQGVEG 517
            G  G  G  G  G+ G PGP G  G P  GV G PGPPGP G+ G+ G+PG PG  GV G
Sbjct: 2345 GRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVG 2404

Query: 518  RDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGH-- 575
                            + ++ +   S +R   G  G  G PGP GPPG PG  GP G   
Sbjct: 2405 FPGQTGP---------RGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASG 2455

Query: 576  ------------PGP---RGVPGIVGAVGQIGN------TGPKGKRGEKGDPGEVG---- 610
                        PGP   RG PGI G  G+ G       TGP G RGE+G+ G+VG    
Sbjct: 2456 LKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGL 2515

Query: 611  RGHPG----MPGPPGIPGLPGRPGQ-------------AINGKDGDRGSPGAPGEAGRPG 653
            +G  G    + GPPG  G  G  G+               NG  GD+GS G PG+ G  G
Sbjct: 2516 KGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAG 2575

Query: 654  LPGPVGLPG 662
            LPG  GL G
Sbjct: 2576 LPGLRGLLG 2584



 Score =  481 bits (1238), Expect = e-136
 Identities = 308/751 (41%), Positives = 359/751 (47%), Gaps = 140/751 (18%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNG-------------------------------- 54
            GP G+RG  G  G  G+PG  G+ G+ G                                
Sbjct: 1910 GPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGS 1969

Query: 55   ----PPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVK-GQPGLPGP 109
                P  + GP G  GE G  G +GP G PG  GL G +G+PGP G PG+  G+ G PGP
Sbjct: 1970 FLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGP 2029

Query: 110  PGLPG-PGFAGPPGPPG------PVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGT 162
             GL G PG  G PG PG        G PGE G RG KG+ G  G  GPPG PG PG PG 
Sbjct: 2030 SGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGP 2089

Query: 163  IQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQ 222
              G + S D   P     G +GPPGL+G KG  G  G  G  G +G PG KGD G  G +
Sbjct: 2090 -PGPKVSVDE--PGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPR 2146

Query: 223  GIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDE 282
            G  G PG  G RG  G  G  G  GP G  G VG  G  GPPG  G  GP G  G  G +
Sbjct: 2147 GQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLK 2206

Query: 283  GSPGIRGP--QGITGPKGATG---PPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAG 337
            G PG  GP  +G+TGP GA G   PPG +G  G  G+PG+ G  G+ G+PG+PG  G +G
Sbjct: 2207 GEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASG 2266

Query: 338  ---------VPGQPGTKGGPGDQGEPGPQGLPGFS--GPPGKEGE--------------- 371
                     VPG PG  G  G +GEPGP G PG +  G PG +GE               
Sbjct: 2267 KDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEP 2326

Query: 372  --------PGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLP 423
                    PGPRGE G  G  G+ GD GE G  G PGP+G +G  G  G PG PGP G P
Sbjct: 2327 GAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGV-GVPGSPGPPGPP 2385

Query: 424  GVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDA 483
            GVKGD G PG  G       PGV G PG+ G +GE G+PGP G++G+ G PG  G  G  
Sbjct: 2386 GVKGDLGLPGLPGA------PGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPL 2439

Query: 484  GAPGVQGYPGPPGPRGLAGNRGVPGQ--PGRQGVEGRDATDQHIVDVALKMLQEQLAEVA 541
            G PG  G  GPPG  GL G++G PG   PG +G  G                        
Sbjct: 2440 GPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGI-------------------- 2479

Query: 542  VSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGH-------------------PGPRGVP 582
                R   G  G  GP G  GPPG  G++G  G                    PGPRG  
Sbjct: 2480 ----RGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAK 2535

Query: 583  GIVGAVGQIGNTGPKGKRGEKGDPGEVG-RGHPGMPGPPGIPGLPGRPG-QAINGKDGDR 640
            G +G  G  G  G KG RG+ GDPG+ G +G PG  G  G+PGL G  G Q   G  G  
Sbjct: 2536 GDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIP 2595

Query: 641  GSPGAPGEAGRPGLPGPVGLPGFCEPAACLG 671
            G PG+PG+ G PG+ G  G  GF  P    G
Sbjct: 2596 GDPGSPGKDGVPGIRGEKGDVGFMGPRGLKG 2626



 Score =  453 bits (1166), Expect = e-127
 Identities = 277/648 (42%), Positives = 330/648 (50%), Gaps = 106/648 (16%)

Query: 26   RGPPGERGPPGPPGPPGVPGSDGIDGDNGP------PGKAGPPGP-----------KGEP 68
            RGPPG  G  G PGPPG PG  G  G  GP      PG+ GPPG             G P
Sbjct: 2173 RGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPP 2232

Query: 69   GKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGV------KGQPGLPGPPGLPGPGFAGPPG 122
            G +G  GP G PG+ G  G  G+PG  G  G       +G PG+PG PGLPGP   GP G
Sbjct: 2233 GPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGP--VGPKG 2290

Query: 123  PPGPVGLPGE--IGIRGPKGDPGPDGPS-----GPPGPPGKPGRPGTIQGLEGSADFLCP 175
             PGP G PG+  +G+ G KG+ G  G       G PG  G  G PG  +G +G A     
Sbjct: 2291 EPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGP-RGEKGEAG---- 2345

Query: 176  TNCPPGMKGPPGLQGVKGHAGKRGILGDPGH--QGKPGPKGDVGASGEQGIPGPPGPQGI 233
                 G  G PG  G KG  G +G  GDPG    G PGP G  G  G+ G+PG PG  G+
Sbjct: 2346 ---RAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGV 2402

Query: 234  RGYPGMAGPKGETG---PHGYKGMVGAIGATG------PPGEEGPRGPPGRAGEKGDEGS 284
             G+PG  GP+GE G   P G +G+ G  G  G      PPG  G  GPPG +G KGD+G 
Sbjct: 2403 VGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGD 2462

Query: 285  PGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGT 344
            PG+    G+ GP+G  G PGI G+DG PG    +G  G  G PGS G +G  G  G  G 
Sbjct: 2463 PGV----GLPGPRGERGEPGIRGEDGRPG---QEGPRGLTGPPGSRGERGEKGDVGSAGL 2515

Query: 345  KGGPGDQ----GEPGPQGLPGFSG---PPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVG 397
            KG  GD     G PGP+G  G  G   P G +G+ GPRG+ G  G  G KG+ G++G  G
Sbjct: 2516 KGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAG 2575

Query: 398  QPG------PQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGV---AG 448
             PG      PQG+ G  G  G PG PG  G+PG++G+KG  G  GPRG  G+ GV    G
Sbjct: 2576 LPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACG 2635

Query: 449  LPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPG 508
            L GEKG+KGE+G PG  G  G +GE G PG  G +GAPG +G  GP G RG  G    PG
Sbjct: 2636 LDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQ---PG 2692

Query: 509  QPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPG------ 562
              G QG +G   T                    +       G  G  GPPGPPG      
Sbjct: 2693 PKGDQGEKGERGTP------------------GIGGFPGPSGNDGSAGPPGPPGSVGPRG 2734

Query: 563  PPGYPGKQGPHGHPGPR--GVPGIVGAV---GQIGNTGPKGKRGEKGD 605
            P G  G++G  G PG R  G PG+ GA    G+ G  GP G RGEKG+
Sbjct: 2735 PEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGE 2782



 Score =  424 bits (1089), Expect = e-118
 Identities = 257/601 (42%), Positives = 300/601 (49%), Gaps = 80/601 (13%)

Query: 25   IRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDG 84
            + GP G  G PGPPGP G+ G  G  G  G  G+ G PG  G  G +G DG  G PG+ G
Sbjct: 2219 LTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPG 2278

Query: 85   L------TGAKGEPGPMGIPG--VKGQPGLPGPPGLPG---------PGFAGPPGPPGPV 127
                    G KGEPGP G PG  V G PG  G  G PG         PG  G  G PGP 
Sbjct: 2279 SPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPR 2338

Query: 128  GLPGEIGIRGPKGDPGPDGPSGPPGP-----------PGKPGRPGTIQGLEGSADFLCPT 176
            G  GE G  G  GDPG DG  G PGP           PG PG PG   G++G        
Sbjct: 2339 GEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGP-PGVKGDLGLPGLP 2397

Query: 177  NCP-----PGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQ 231
              P     PG  GP G  G  G +G+RG+ G PG +G PGP G  G  G  G PG  G +
Sbjct: 2398 GAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLK 2457

Query: 232  GIRGYPGMA--GPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRG 289
            G +G PG+   GP+GE G  G +G  G  G  GP G  GP G  G  GEKGD GS G++G
Sbjct: 2458 GDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKG 2517

Query: 290  PQGIT-------GPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQP 342
             +G +       GP+GA G  G  G  G  G  G +G  G  G  GS G  G  G  G P
Sbjct: 2518 DKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLP 2577

Query: 343  GTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQ 402
            G +G  G QG+PG  G+PG  G PGK+G PG RGE G  G MG +G +GERG  G  G  
Sbjct: 2578 GLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLD 2637

Query: 403  GRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEP 462
            G +G KGE GPP      G PG+ G KG  G+ G  G+ G PG  GL G KG++G  G+P
Sbjct: 2638 GEKGDKGEAGPP------GRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQP 2691

Query: 463  GPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATD 522
            GPKG QG +GE          G PG+ G+PGP G  G AG  G PG  G +G EG     
Sbjct: 2692 GPKGDQGEKGE---------RGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEG----- 2737

Query: 523  QHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVP 582
                      LQ Q  E     +R       ++G PG PG PG  G+QG  G  GPRG  
Sbjct: 2738 ----------LQGQKGERGPPGER-------VVGAPGVPGAPGERGEQGRPGPAGPRGEK 2780

Query: 583  G 583
            G
Sbjct: 2781 G 2781



 Score =  386 bits (991), Expect = e-107
 Identities = 238/553 (43%), Positives = 271/553 (49%), Gaps = 92/553 (16%)

Query: 174  CPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGI 233
            CP  CP G KG PG  G++G  G  G  G PG  G PGP+G  G++  +G  G PG  G 
Sbjct: 1247 CPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGR 1306

Query: 234  RGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGD---------EGS 284
             G PG AG  G  G  G KG  G  G  G PGE GPRGP G  G  G           G 
Sbjct: 1307 PGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGR 1366

Query: 285  PGIRGPQGITGPKGATGPPGINGKDGTPGT--PGMKGSAGQAGQPG------SPGHQGLA 336
             G  GP G  GP+G  G PG  G  G PGT   G KG  G+ G PG      +PG  GL 
Sbjct: 1367 KGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLP 1426

Query: 337  GVPGQPGTK---GGPGDQGEPG--PQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQG 391
            G+PG PG +   G PG +GE G    G PG  G PG  GE GPR   GP G +G KGD+G
Sbjct: 1427 GLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPR---GPPGAIGPKGDRG 1483

Query: 392  ERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLP- 450
              GP+G+ G +G +GP G  G  G+PG  G PG KG +G PG TG +G+ G+PG  G P 
Sbjct: 1484 FPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPA 1543

Query: 451  -------GEKGEKGESGEPGPKGQQGVRGE--------PGYPGPS---GDAGAPGVQGYP 492
                   G KGEKG+ G  GP+G  GV+GE        PG PGP    GD G  G+ G  
Sbjct: 1544 VVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRA 1603

Query: 493  GPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAV 552
            GPPG  G  G +G PG+PG  G  G    D                           G V
Sbjct: 1604 GPPGDSGPPGEKGDPGRPGPPGPVGPRGRD---------------------------GEV 1636

Query: 553  GMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-- 610
            G  G  GPPG PG PGK G     G RG PG+ G VG+ G+ G  G+ G  G PG  G  
Sbjct: 1637 GEKGDEGPPGDPGLPGKAGER---GLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPK 1693

Query: 611  --RGHPGMPGPPG----------IPGLPGRPGQ-AINGKDGDRGSPGAPGEAGRPGL--- 654
              RG PG PGPPG            G PG  GQ    G  GD G PGAPGE G  G    
Sbjct: 1694 GDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGP 1753

Query: 655  PGPVGLPGFCEPA 667
            PGP G PG   PA
Sbjct: 1754 PGPQGDPGVRGPA 1766



 Score =  221 bits (564), Expect = 1e-57
 Identities = 130/305 (42%), Positives = 152/305 (49%), Gaps = 47/305 (15%)

Query: 23   AQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGI 82
            A I GPP   GP G  G  G  G  G+DGD GP G  G PG KG  G+ G  G  G PG+
Sbjct: 2523 AVILGPP---GPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGL 2579

Query: 83   DGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDP 142
             GL G +G+PG  GIPG  G PG  G PG+ G    G  G  GP GL GE G++G  G  
Sbjct: 2580 RGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGE--KGDVGFMGPRGLKGERGVKGACGLD 2637

Query: 143  GPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGIL- 201
            G  G  G  GPPG+PG  G                   G  G PG+ G  G  GK G++ 
Sbjct: 2638 GEKGDKGEAGPPGRPGLAG-----------------HKGEMGEPGVPGQSGAPGKEGLIG 2680

Query: 202  --GDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIG 259
              GD G  G+PGPKGD G  GE+G P      GI G+PG +G  G  GP           
Sbjct: 2681 PKGDRGFDGQPGPKGDQGEKGERGTP------GIGGFPGPSGNDGSAGP----------- 2723

Query: 260  ATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKG 319
              GPPG  GPRGP G  G+KG+ G PG R    + G  G  G PG  G+ G PG  G +G
Sbjct: 2724 -PGPPGSVGPRGPEGLQGQKGERGPPGER----VVGAPGVPGAPGERGEQGRPGPAGPRG 2778

Query: 320  SAGQA 324
              G+A
Sbjct: 2779 EKGEA 2783



 Score =  221 bits (562), Expect = 2e-57
 Identities = 150/394 (38%), Positives = 181/394 (45%), Gaps = 87/394 (22%)

Query: 353  EPGPQGLPGFSGPPGKEGEPGP---RGEIGP---QGIMGQKGDQGERGPVGQ-------- 398
            +P P+  P +  P G++GEPG    RG++GP    G+ G+ G  G +GP G         
Sbjct: 1241 QPRPEPCPVYC-PKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERG 1299

Query: 399  -PGPQGRQGPKGEQGPPGIPGPQGL---PGVKGDKGSPGKTGPRGKVGDPGV-------- 446
             PG  GR G  G  G PG PG  GL   PG+ G +G PG+ GPRG  G+PG         
Sbjct: 1300 FPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGE 1359

Query: 447  -AGLPGEKGEKGESGEPGP--------------------KGQQGVRGEPGYPGPS----- 480
              GLPG KG+ G SG PGP                    KG +G RGE G PGP      
Sbjct: 1360 GPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIA 1419

Query: 481  -GDAGAPGVQGYPGPPGPRGLAGNR-----------GVPGQPGRQGVEGRDATDQHIVDV 528
             G+ G PG+ G PGP GP G  G +           G+PGQPG  G +G       I   
Sbjct: 1420 PGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPK 1479

Query: 529  ALKMLQEQLAEVAVSAKREALGAVGMMGPP---------GPPGPPGYPGKQGPHGHPGPR 579
              +     L E     +R   G  G  G P         GP GPPG  G+QG  G PG  
Sbjct: 1480 GDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRP 1539

Query: 580  GVPGIVGAV--------GQIGNTGPKGK---RGEKGDPGEVGRGHPGMPGPPGIPGLPGR 628
            G P +VG          G +G  GP+G    +GE+G PG V  G PG  G PG  G  G 
Sbjct: 1540 GDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGL 1599

Query: 629  PGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPG 662
             G+A  G  GD G PG  G+ GRPG PGPVG  G
Sbjct: 1600 TGRA--GPPGDSGPPGEKGDPGRPGPPGPVGPRG 1631



 Score = 31.6 bits (70), Expect = 2.6
 Identities = 14/30 (46%), Positives = 16/30 (53%)

Query: 19   VLALAQIRGPPGERGPPGPPGPPGVPGSDG 48
            V+    + G PGERG  G PGP G  G  G
Sbjct: 2752 VVGAPGVPGAPGERGEQGRPGPAGPRGEKG 2781


>gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]
          Length = 1714

 Score =  502 bits (1292), Expect = e-142
 Identities = 315/765 (41%), Positives = 370/765 (48%), Gaps = 116/765 (15%)

Query: 19   VLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDG 78
            +L +  +RGP G+ GPPGPPGP G+PG  G  G  G PG  G PG  G PG  GP G  G
Sbjct: 481  MLEMEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPG 540

Query: 79   ---------KPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPG-PGFAGPPGPPGPVG 128
                     + G  GL+G  G PG  G  G+KG PGLPG PG  G PGFAG  G PG   
Sbjct: 541  FSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPG--- 597

Query: 129  LPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGT-----IQGLEGSADFLCPTNCPP--G 181
             PG  G+ GP+G+PGP G  G  G PG+ G+ G      I G+ G   F      P   G
Sbjct: 598  YPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFG 657

Query: 182  MKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAG 241
             +GP GL G  G  G  G  G PG +G  GP G +G +G   IPGP G  G +G PG+ G
Sbjct: 658  DRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAG---IPGPMGLSGNKGLPGIKG 714

Query: 242  PKGETG---------------------PHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKG 280
             KGE G                     P G +G  G  G TG PG +GP GPPG  G  G
Sbjct: 715  DKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPG 774

Query: 281  DEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPG 340
            D G PG  GP+G  G  G  GPPG  G  GT G  G  G+ G+ G  G PG +G AG PG
Sbjct: 775  DIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPG 834

Query: 341  QPGTKGGPGDQ------GEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERG 394
              G KG  GDQ      GE GP GLPG  G  G  GE G RG  GP G  G+KG  G  G
Sbjct: 835  PEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPG 894

Query: 395  PVGQP---------------GPQGRQGPKGE---QGPPGIPGPQGLPGVKGDKGSPGKTG 436
            P G P               GP G QGPKG+   +GP G+ G QG+ G KG+KG  GK G
Sbjct: 895  PPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRG 954

Query: 437  PRGKV------------GDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEP---GYPGPSG 481
            P G +            G PG+ GLPG  G++G  GEPG +G QG  G P   G  GP G
Sbjct: 955  PHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPG 1014

Query: 482  DAGAPGVQGYPGPPGPRGLAGN---------RGVPGQPGRQGVEGRDATDQHIVDVALKM 532
              G  G+QG PG  G  G AG+         RG PG PG +G++G+D          L  
Sbjct: 1015 TEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPG 1074

Query: 533  LQEQLAEVAVSAKREALGAVGMMGPPGP------PGPPGYPGKQGPHGHPGPRGVPGIVG 586
               +  E+ +      LG  G  G PGP      PG  G PGK+G  G  GP G  G  G
Sbjct: 1075 EDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRG 1134

Query: 587  AVGQIGNTGPKGKRGEKGDPGEVG-------------RGHPGMPGPPGIPGLPGRPG--- 630
              G+IG +GPKG RG +G  G +G             RGH G PGP G+PG  G  G   
Sbjct: 1135 PPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPG 1194

Query: 631  --QAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGAS 673
                + G  G RG PG  G+ G  G PG  G  G        GA+
Sbjct: 1195 EDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGAT 1239



 Score =  499 bits (1286), Expect = e-141
 Identities = 308/739 (41%), Positives = 364/739 (49%), Gaps = 114/739 (15%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGI---D 83
            GP G+ G PG  GP G PG +G  GD G PG+ GP GPKG  G  GP GP G  G    +
Sbjct: 750  GPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEE 809

Query: 84   GLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP----------GFAGPPGPPGPVGLPGEI 133
            G  GA GE GP G PG KG  G PGP GL G           G  GP G PG VG+ G I
Sbjct: 810  GPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSI 869

Query: 134  GIRGPKGDPGPDGPSGP------PGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPG 187
            G +G +G PGP GP G       PGPPG PG  G + GL G            G +GPPG
Sbjct: 870  GEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPL-GLPGHV----------GARGPPG 918

Query: 188  LQGVKGHAGKRG---ILGDPGHQGKPGPKGDVGASGEQGI---PGPPGPQGIRGYPGMAG 241
             QG KG  G RG   +LG+ G QG  G KGD G  G  G+    G PG +G +G PG+ G
Sbjct: 919  SQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQG 978

Query: 242  PKGETGPHGYKG---MVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKG 298
              G TG  G  G   + G  G  GPPGE G  GPPG  GE G +G PG +G  G  G  G
Sbjct: 979  LPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVG 1038

Query: 299  ATGPPGINGKDGTPGT------------------------------PGMKGSAGQAGQPG 328
             TG PG+ G+ G PG                               PG+ G  G++GQ G
Sbjct: 1039 GTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTG 1098

Query: 329  SPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGP------RGEIGPQG 382
             PG +G+ G+PGQ G  G  GD+G+ GP G  G  GPPGK G+ GP      RG +G  G
Sbjct: 1099 LPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLG 1158

Query: 383  IMGQKGDQG---ERGPVGQPGPQGRQGPKGEQGPPGI-------PGPQGLPGVKGDKGSP 432
            +MG  G+ G    RG  GQPGP G  GPKGE+G PG        PGP+G PG  GD+G  
Sbjct: 1159 LMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGER 1218

Query: 433  GKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGE---------PGYPGPSGDA 483
            G+ G  G  G  GV GL G  G++G  GEPG +G+QG++GE          G PGPSG  
Sbjct: 1219 GEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKP 1278

Query: 484  GAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVS 543
            G PG+QG  GP G +G  G  G+ G PG+ G  G+              L        V 
Sbjct: 1279 GIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVK 1338

Query: 544  AKREALGAVGMMGPPGPPGPPGYPGKQGPHGH------------PGPRGVPGIVGAVGQI 591
                  G+ G+ GP G  G PG PG QG  GH            PG +G PG  G  G  
Sbjct: 1339 GSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLT 1398

Query: 592  GNTGPKGKRGEKGDPGEVGR-------GHPGMPGPPGIPGLPGRPGQA-INGKDGDRGSP 643
            G  G  G +G +GD G VG        GH G  GP G  G+ G  G+    G+ G RG  
Sbjct: 1399 GFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGET 1458

Query: 644  GAPGEAGRPGLPGPVGLPG 662
            G  G  G+PG PGP G PG
Sbjct: 1459 GPQGPRGQPGPPGPPGAPG 1477



 Score =  488 bits (1257), Expect = e-138
 Identities = 303/741 (40%), Positives = 357/741 (48%), Gaps = 124/741 (16%)

Query: 26   RGPPGERGPPG---PPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGI 82
            RGP G  G PG     GPPG PG  G  G  GP G AG PGP G  G  G  G  G  G 
Sbjct: 659  RGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGE 718

Query: 83   DGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPG----------PGFAGPPGPPGPVGLPGE 132
             G  G  GEPG    PG KG  GLPGPPG+ G          PG  GP GPPGP G PG+
Sbjct: 719  QGTAGELGEPG---YPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGD 775

Query: 133  IGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADF---LCPTNCP--PGMKGPPG 187
            IGI G  G  GP G  G  GPPG PG  GT QG EG       L P   P   G  G PG
Sbjct: 776  IGIPGQNGPEGPKGLLGNRGPPGPPGLKGT-QGEEGPIGAFGELGPRGKPGQKGYAGEPG 834

Query: 188  LQGVKGHAGKRGILGDPGHQGKPGPKGDVGASG------EQGIPGPPGPQGIRGYPGMAG 241
             +G+KG  G +G +G  G  G  G  G+VG +G      E+G PGP GPQG +G  G  G
Sbjct: 835  PEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPG 894

Query: 242  PKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATG 301
            P G  GP G  G+ G +GA GPPG +GP+G  G  G  G  G  GI+G +G  G +G  G
Sbjct: 895  PPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRG 954

Query: 302  PPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPG 361
            P G+ GK G PG  G +G  G  G PGS G +GL G PG  G +G  G  GE G +G PG
Sbjct: 955  PHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPG 1014

Query: 362  FSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGP-------------- 407
              G  G +GEPG +G++G  G +G  G+ G RG  G PG +G QG               
Sbjct: 1015 TEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPG 1074

Query: 408  ----KGEQGPPGI------------PGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPG 451
                KGE G PGI            PGP+G+ G+ G +G PGK G +G++G  G  G  G
Sbjct: 1075 EDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRG 1134

Query: 452  EKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPG 511
              G+ G+SG  G +G +G  G  G  GP G+ G PG +G+ G PGP GL      PG  G
Sbjct: 1135 PPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGL------PGPKG 1188

Query: 512  RQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQG 571
             +G  G D+T                                ++GPPGP G PG  G QG
Sbjct: 1189 EKGYPGEDST--------------------------------VLGPPGPRGEPGPVGDQG 1216

Query: 572  PHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG----------RGHPGMPGPPG 621
              G PG  G  G VG  G  G TG +G  GE GD GE G          +G  G PGP G
Sbjct: 1217 ERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSG 1276

Query: 622  IPGLPGRPG-------------QAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAA 668
             PG+PG  G               I+G  G  G PG  G  G  G PG  GL G   P  
Sbjct: 1277 KPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPG 1336

Query: 669  CLGASAYASARLTEPGSIKGP 689
              G+S    +    PG I+GP
Sbjct: 1337 VKGSSGLPGS----PG-IQGP 1352



 Score =  347 bits (889), Expect = 3e-95
 Identities = 213/494 (43%), Positives = 253/494 (51%), Gaps = 75/494 (15%)

Query: 211 GPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPR 270
           GPKGD G       PGPPGP GI G  G  GP+G  GPHG  G+ G  G  GP G+ G  
Sbjct: 489 GPKGDTGP------PGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFS 542

Query: 271 GPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSP 330
                 GEKGD+G  G+ GP G+ G KG  G PG+    G PG  G+ G AG  G PG P
Sbjct: 543 PGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGL---PGLPGEQGIPGFAGNIGSPGYP 599

Query: 331 GHQGLAGVPGQPGTKGG------PGDQGEPGPQG---LPGFSGPPG---KEGEPGPRGEI 378
           G QGLAG  G PG KG       PG+ G+ GP+G   +PG  G  G   ++G PG  G+ 
Sbjct: 600 GRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDR 659

Query: 379 GPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPR 438
           GP G+ G  G  G  GP G PG +G  GP G  GP GIPGP GL    G+KG PG  G +
Sbjct: 660 GPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGL---SGNKGLPGIKGDK 716

Query: 439 GKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPR 498
           G+ G  G  G PG  G+KG  G PGP G +G  G      PSG  G PG+QG  GPPGP 
Sbjct: 717 GEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSG------PSGQTGDPGLQGPSGPPGPE 770

Query: 499 GLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPP 558
           G  G+ G+PGQ G +G +G                                  +G  GPP
Sbjct: 771 GFPGDIGIPGQNGPEGPKG---------------------------------LLGNRGPP 797

Query: 559 GPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPG 618
           GPPG  G  G++GP G  G  G  G  G  G  G  GP+G +GE GD G +G+   G  G
Sbjct: 798 GPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGK--IGETG 855

Query: 619 PPGIPGLPGRPGQAINGKDGDRGSP---GAPGEAGRPGLPGPVGLPGFCEPAACLGASAY 675
           P G+PG  G  G    G+ G+RGSP   G  GE G  G PGP G+PG   P   LG   +
Sbjct: 856 PVGLPGEVGMTGSI--GEKGERGSPGPLGPQGEKGVMGYPGPPGVPG---PIGPLGLPGH 910

Query: 676 ASARLTEPGSIKGP 689
             AR   PGS +GP
Sbjct: 911 VGAR-GPPGS-QGP 922



 Score =  231 bits (589), Expect = 2e-60
 Identities = 133/293 (45%), Positives = 159/293 (54%), Gaps = 24/293 (8%)

Query: 25   IRGPPGERGPPGP---PGPPGVPGSDGIDGDNGPP---GKAGPPGPKGEPGKAGPDGPDG 78
            + GPPG RG PGP    G  G PG++G  G  G P   G  G  GP GEPG  G  G  G
Sbjct: 1199 VLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKG 1258

Query: 79   KPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPG-PGFAGPPGPPGPVGLPGEIGIRG 137
            + G +G  G KG PGP G PG+ G  GL GP G+ G  G  G  G PG +G PG+ G+ G
Sbjct: 1259 ERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPG 1318

Query: 138  PKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGH--- 194
             +G PG  G +G PGPPG  G      GL GS     P     G+ G PG+QG +GH   
Sbjct: 1319 IRGGPGRTGLAGAPGPPGVKGS----SGLPGSPGIQGPKG-EQGLPGQPGIQGKRGHRGA 1373

Query: 195  AGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGM 254
             G +G  GDPG +G+PG  G  G +G QG PGP GP+G  G  G++GPKG          
Sbjct: 1374 QGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGP--------- 1424

Query: 255  VGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGING 307
            +G  G TGP G EG  GP GR G +G++G  G  GPQG  G  G  GPPG  G
Sbjct: 1425 IGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPG 1477



 Score =  202 bits (515), Expect = 6e-52
 Identities = 118/264 (44%), Positives = 136/264 (51%), Gaps = 28/264 (10%)

Query: 25   IRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDG---PDGKPG 81
            +RG  G++GPPG PG  G  G  G  G  G  GK G PGP G+PG  G  G   P G  G
Sbjct: 1235 LRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQG 1294

Query: 82   IDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGD 141
              G  G  G PG +G PG +G PG+ G PG    G AG PGPP         G++G  G 
Sbjct: 1295 YHGADGISGNPGKIGPPGKQGLPGIRGGPG--RTGLAGAPGPP---------GVKGSSGL 1343

Query: 142  PGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGIL 201
            PG  G  GP G  G PG+PG IQG  G            G +GP G  G+KG  G+ G+ 
Sbjct: 1344 PGSPGIQGPKGEQGLPGQPG-IQGKRGHRG-------AQGDQGPCGDPGLKGQPGEYGVQ 1395

Query: 202  GDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIR------GYPGMAGPKGETGPHGYKGMV 255
            G  G QG PGPKG  G +G  GI GP GP G R      G  G+ GP G TGP G KG  
Sbjct: 1396 GLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFR 1455

Query: 256  GAIGATGPPGEEGPRGPPGRAGEK 279
            G  G  GP G+ GP GPPG  G +
Sbjct: 1456 GETGPQGPRGQPGPPGPPGAPGPR 1479



 Score =  137 bits (345), Expect = 3e-32
 Identities = 86/193 (44%), Positives = 95/193 (49%), Gaps = 31/193 (16%)

Query: 22   LAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPG 81
            L  IRG PG  G  G PGPPGV GS G+      PG  G  GPKGE G  G  G  GK  
Sbjct: 1316 LPGIRGGPGRTGLAGAPGPPGVKGSSGL------PGSPGIQGPKGEQGLPGQPGIQGK-- 1367

Query: 82   IDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGD 141
              G  GA+G+ GP G PG+KGQPG  G  GL   GF G PGP GP G  G +GI GPKG 
Sbjct: 1368 -RGHRGAQGDQGPCGDPGLKGQPGEYGVQGL--TGFQGFPGPKGPEGDAGIVGISGPKGP 1424

Query: 142  PGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGIL 201
             G  G +GP G  G  G                    P G  GP G +G +G  G +G  
Sbjct: 1425 IGHRGNTGPLGREGIIG--------------------PTGRTGPRGEKGFRGETGPQGPR 1464

Query: 202  GDPGHQGKPGPKG 214
            G PG  G PG  G
Sbjct: 1465 GQPGPPGPPGAPG 1477



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 26/63 (41%), Positives = 34/63 (53%)

Query: 19   VLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDG 78
            ++ ++  +GP G RG  GP G  G+ G  G  G  G  G  G  GP+G  G+ GP GP G
Sbjct: 1415 IVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPG 1474

Query: 79   KPG 81
             PG
Sbjct: 1475 APG 1477


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
            sapiens]
          Length = 1424

 Score =  499 bits (1286), Expect = e-141
 Identities = 321/748 (42%), Positives = 364/748 (48%), Gaps = 110/748 (14%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGID-----------------GDNGPPGK----------- 58
            GP G RGP GP GPPGVPGS G                   G+ G PGK           
Sbjct: 363  GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGC 422

Query: 59   AGPPGPKGEPGKAGPDGP----DGKPGIDGLTGAKGEPGPMGIPGVKGQPGL-------- 106
            AG PG  G PG  GP G      G PG  GL G  G PG  G+ G KG+PGL        
Sbjct: 423  AGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYI 482

Query: 107  PGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGL 166
            PGPPGLPG      PG  G  G+PG  G  G KG PG  G +G PG PG PG  G   GL
Sbjct: 483  PGPPGLPGL-----PGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGD-PGL 536

Query: 167  EGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPG 226
            +G            G+ G PGL+G  G  G  GI G PG +G PGPKG++  SGE+G  G
Sbjct: 537  KGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQG 596

Query: 227  PPGPQGIRGYPGMAGPKGETG-----PHGYKGMVGAIGATGPPGEEGPRGP-------PG 274
            PPG  G  G PG AGP G  G       G +G  G  GA GPPGE GPRG        PG
Sbjct: 597  PPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG 656

Query: 275  RAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGM--------KGSAGQAGQ 326
              G  G  G PG +GP GI G  G  G PG+ G DG PG PG+        KG  G  G 
Sbjct: 657  PPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGT 716

Query: 327  PGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQ--GLPGFSGPPGKEGEPGPRGEIGPQGIM 384
             GS G  G  G PG PG  G PG +GEP     G PG  G PG+ G  G  GEIG  G+ 
Sbjct: 717  KGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLP 776

Query: 385  GQKGDQGERGPVGQPGPQGRQGPKGEQGPPG--IPGP---QGLPGVKGDKGSPGKTGPRG 439
            G  G  G  G  G  G  G+ GP GEQGPPG  I GP   QGLPG+ G KG  G+ G  G
Sbjct: 777  GLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTG 836

Query: 440  KVGDPGVAGL-----PGEKGEKG---ESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGY 491
              GDPG+ GL     PGE G  G     GE GP GQ+G  G PG  GP G+ G  G+ G+
Sbjct: 837  PKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGF 896

Query: 492  PGPPGPRGLAGNRGVPGQ---PGRQGVEGRDATD-----------------QHIV----D 527
            PG  GP G  GN G PGQ   PG  GV+G+  T                   H++    +
Sbjct: 897  PGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGE 956

Query: 528  VALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGA 587
              LK       E          G  G+ G PGP GPPG  G  G  G+PG  G+ GI G+
Sbjct: 957  PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016

Query: 588  VGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAIN---GKDGDRGSPG 644
            +G +G  G KGKRG  G PG  GR  PG+PG  G+ G  G PG +     G  G  G PG
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGR--PGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPG 1074

Query: 645  APGEAGRPGLPGPVGLPGFCEPAACLGA 672
             PG+ G+ G  G  G PG   PA   GA
Sbjct: 1075 LPGDMGKKGEMGQPGPPGHLGPAGPEGA 1102



 Score =  498 bits (1282), Expect = e-141
 Identities = 298/687 (43%), Positives = 349/687 (50%), Gaps = 93/687 (13%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKA--GPDGPDGKPGIDG 84
            G  GE G PG PG PG PG++G+DG  G PG+ GPPG +G PG+   GP G  G PG++G
Sbjct: 765  GEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNG 824

Query: 85   LTGA---KGEPGPMGIPGVKG--QPGLPGPPGLPG-PGFAGPPGPPGPVGLPGEIGIRGP 138
            L G    +G+ GP G PG+ G  + G PG  G PG PG  G  GP G  G PG  GI GP
Sbjct: 825  LKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP 884

Query: 139  KGDPGPDGPSGPPG---PPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHA 195
             G+ G  G  G PG   PPG PG PGT                 PG +G PG+ GVKG  
Sbjct: 885  PGEDGVIGMMGFPGAIGPPGPPGNPGT-----------------PGQRGSPGIPGVKGQR 927

Query: 196  GKRGILGDPGHQGKPGP---------KGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGET 246
            G  G  G+ G +G PGP         KG+ G  G  G PG  G +G+ G PG+ G KG  
Sbjct: 928  GTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLP 987

Query: 247  GPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGIN 306
            GP G  G  G +G+TG PGE G RG PG  G  G  GS G RG  G  G  G  G PGI+
Sbjct: 988  GPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIH 1047

Query: 307  GKDGTPGTPGMK-----GSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPG 361
            G  G  G PG       G  G  G PG PG  G  G  GQPG    PG  G  GP+G PG
Sbjct: 1048 GLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP---PGHLGPAGPEGAPG 1104

Query: 362  FSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGP---KGEQGPPGIPG 418
              G PG  G+PGP G++G +GI G  G  G RGP G PG  G  GP   +G+QG  GIPG
Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG 1164

Query: 419  PQGLPGVKG-------DKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVR 471
            P G  G  G        +G+PG  G +G  G PG  GLPG KG  G++G  GP G +G  
Sbjct: 1165 PAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFP 1224

Query: 472  GEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQ--GVEGRDATDQHIVDVA 529
            G PG PG    A  PG  G  GPPG RG  G  G PG PG    G++G   +  H     
Sbjct: 1225 GPPGLPG----AIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGH----- 1275

Query: 530  LKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGI----- 584
                            +   G  G MGPPG  G PG PG  GP G PG +G PG+     
Sbjct: 1276 -------------PGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKG 1322

Query: 585  ----VGAVGQIGNTGPKGKRGEKGDPGEVG----RGHPGMPGPPGIPGLPGRPGQ-AING 635
                +G++G  G  GPKG  G +GDPG +      G PG PG PG PG+ G PG     G
Sbjct: 1323 NPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPG 1382

Query: 636  KDGDRGSPGAPGEAGRPGLPGPVGLPG 662
              G  G  G PG+ G+PG PGP G  G
Sbjct: 1383 NLGPCGPRGKPGKDGKPGTPGPAGEKG 1409



 Score =  488 bits (1256), Expect = e-138
 Identities = 319/765 (41%), Positives = 374/765 (48%), Gaps = 137/765 (17%)

Query: 25   IRGPPGERGPPGPPGPPGVPGS---------DGIDGDNGPPGKAGPPGPKGEPGKAGPDG 75
            +RG PG +G  G PG PGV G           G  GD GPPG  G PG  G  G AGP G
Sbjct: 558  LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617

Query: 76   --PDGKPGIDGLTGAKGEPGPMGIPGVKGQ-------PGLPGPPGLPG-PGFAGPPGPPG 125
              P G+PG+ G  G  G PGP G  G +G+       PG PGPPG PG PG  GPPG PG
Sbjct: 618  YGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPG 677

Query: 126  PVGLPGEIGIRGPKGDPGPDGPS--GPPGPPGKPGRPGTIQGLEGSADFLCPTNC-PPGM 182
             +G  G+ G+ GP G+PG  G    GPPGP G  G PGT    +GS    CP     PG+
Sbjct: 678  SLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGT----KGSLG--CPGKMGEPGL 731

Query: 183  KGPPGLQGVKGHA-----GKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGI---R 234
             G PGL G KG       G  G  G PG +G  G  G++G  G  G+PG PG +G+   R
Sbjct: 732  PGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPR 791

Query: 235  GYPGMAGPKGETGP-----------HGYKGMVGAIGATGPPGEEGPRGPPG-----RAGE 278
            G PG  GP GE GP            G  G+ G  G  G  G+ GP+G PG     R+G 
Sbjct: 792  GDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGF 851

Query: 279  KGDEGSPGIRGPQGITGP---------KGATGPPGINGKDGTPGTPGMKGSAGQAGQPGS 329
             G+ GSPGI G QG  GP          G  GPPG +G  G  G PG  G  G  G PG+
Sbjct: 852  PGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGT 911

Query: 330  PGHQGLAGVPG------QPGTKGGPGDQGEPGPQ------------GLPGFSGPPGKEGE 371
            PG +G  G+PG       PG KG  GD+G PGP             GL GF+G PG++G 
Sbjct: 912  PGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGN 971

Query: 372  ---------------PGPRGEIGPQGIMGQKGDQGE---------RGPVGQPGPQGRQGP 407
                           PGP G  GP+G +G  G+ GE          G +G PG +G++G 
Sbjct: 972  RGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGT 1031

Query: 408  KGEQGPPGIPGPQGLPGVKGDKGSPG-----KTGPRGKVGDPGVAGLPGEKGEKGESGEP 462
             G  G  G PG  G+ G++GDKG PG     + GP G  GDPG   LPG+ G+KGE G+P
Sbjct: 1032 LGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPG---LPGDMGKKGEMGQP 1088

Query: 463  GPKGQQGVRGE------------PGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQP 510
            GP G  G  G             PG PGP GD G  G++G  GPPG RG  G  G PG P
Sbjct: 1089 GPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSP 1148

Query: 511  GRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQ 570
            G  G+ G    D  I   A +  +  L   A    R   GA G  G  G PG PG PG++
Sbjct: 1149 GPMGIRGDQGRDG-IPGPAGEKGETGLLR-APPGPRGNPGAQGAKGDRGAPGFPGLPGRK 1206

Query: 571  GPHGHPGPRGVPGIVGAVGQIGNTGP--KGKRGEKGDPGEVGR-GHPGMPGPPGI----- 622
            G  G  GPRG  GI G  G  G  G    G+ G +G PG  G  G PG PGPPG      
Sbjct: 1207 GAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGI 1266

Query: 623  ---PGLPGRPG-QAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGF 663
                G  G PG +   G  GD G PG  G  G PGLPGP G PGF
Sbjct: 1267 KGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGF 1311



 Score =  484 bits (1247), Expect = e-137
 Identities = 306/735 (41%), Positives = 368/735 (50%), Gaps = 120/735 (16%)

Query: 27  GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLT 86
           G PG +GP G PG PG+ GS G+ G +G PG +G PG  G PG  GP G  G PG    +
Sbjct: 70  GLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGC---S 126

Query: 87  GAKGEPGPMGIPGVKGQPGLPGPPGLPGP---------------GFAGPPGPPGPVGLPG 131
           G+KGE G  G+PG  G PG+PG  GL G                G  G PG PGP GLPG
Sbjct: 127 GSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPG 186

Query: 132 EIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTI-------QGLEGSADFLCPTNCPPG--- 181
             G  GP G PGP G  G PG  G  G  G +       +G  G      P   PPG   
Sbjct: 187 PPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPG-PPGTVI 245

Query: 182 --MKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGAS--GEQGIPGPPGPQGIRGYP 237
             + GP     +KG  G +G +G+P   G PGP G  G S   E+G PG PG QG  G  
Sbjct: 246 VTLTGPDNRTDLKGEKGDKGAMGEP---GPPGPSGLPGESYGSEKGAPGDPGLQGKPGKD 302

Query: 238 GMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAG---------EKGDEGSPGIR 288
           G+ G  G  G  G +G  G +G  G  G++G  GPPG  G         EKGDEG+PG  
Sbjct: 303 GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP 362

Query: 289 GPQGITGPKGATGPPGINGKDGT--------PGTPGMKGSAGQAGQ--------PGSPGH 332
           GP+G  GP+G +GPPG+ G  G+        PG PG+KGS G+ G+        PGSPG 
Sbjct: 363 GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGC 422

Query: 333 QGLAGVPGQPGTKGGPGD----QGEPGPQGLPGFSGPPGKEGEPGPRGE----------- 377
            G  G+PG PG  G PGD    +G PG  GLPG+ G PG  G  GP+GE           
Sbjct: 423 AGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYI 482

Query: 378 IGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTG- 436
            GP G+ G  G  G +G  G+ G  G +G  G  G  G+PG  G PG +GD G  G+ G 
Sbjct: 483 PGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGE 542

Query: 437 ---PRGKV---GDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQG 490
              P G+V   GDPG+ G PG KG  G  G PG KG  G +GE    G  GD G PG  G
Sbjct: 543 TLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPG 602

Query: 491 YPGPPGPRGLAG--NRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREA 548
            PG PGP G AG    G  G+PG QG +G         +   +       E++VS     
Sbjct: 603 SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPR------GELSVSTP--- 653

Query: 549 LGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGV---PGIVGAVGQ-----IGNTGPKGKR 600
                + GPPGPPGPPG+PG QGP G PG  G    PG+ G  G+     IG  GP G +
Sbjct: 654 -----VPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPK 708

Query: 601 GEKGDPGEVG-------RGHPGMPGPPGIPGLPGRP------GQAINGKDGDRGSPGAPG 647
           G++G PG  G        G PG+PG PG+PG  G P      G    G  G+RG+ G  G
Sbjct: 709 GDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHG 768

Query: 648 EAGRPGLPGPVGLPG 662
           E G PGLPG  G PG
Sbjct: 769 EIGLPGLPGLPGTPG 783



 Score =  483 bits (1243), Expect = e-136
 Identities = 311/752 (41%), Positives = 358/752 (47%), Gaps = 157/752 (20%)

Query: 28   PPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTG 87
            P G+ G PG PG  G PG  G+DG  G PG  G PGPKGE   +G  G  G PG  G  G
Sbjct: 546  PEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPG 605

Query: 88   AKGEPGPMGIPGV--KGQPGLPGPPGLPG----PGFAGP----------PGPPGPVGLPG 131
            + G  GP G PG   +G+PGL G  G+PG    PG AGP          PGPPGP G PG
Sbjct: 606  SPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665

Query: 132  EIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGV 191
              G +GP G PG  G  G PG PG  G PG I G+            PPG KG  G  G 
Sbjct: 666  HPGPQGPPGIPGSLGKCGDPGLPGPDGEPG-IPGIGFPG--------PPGPKGDQGFPGT 716

Query: 192  KGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGY 251
            KG  G  G +G+PG  GKPG  G   A GE  +  P GP    G PG  G +G +G HG 
Sbjct: 717  KGSLGCPGKMGEPGLPGKPGLPG---AKGEPAVAMPGGP----GTPGFPGERGNSGEHGE 769

Query: 252  KGMVGAIGATGPPGEEG---PRGPPGRAGEKGDEGSPG--IRGPQG------ITGPKGAT 300
             G+ G  G  G PG EG   PRG PG+ G  G++G PG  I GP+G      + G KG  
Sbjct: 770  IGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQ 829

Query: 301  GPPGINGKDGTPGTPGM--KGSAGQAGQPGSPGHQ------GLAGVPGQPGTKGGPGDQG 352
            G  G  G  G PG PG+   G  G+ G PG PGHQ      G  G PG PG  G PG+ G
Sbjct: 830  GRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDG 889

Query: 353  EPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGD------QGERGPVGQPGPQ---- 402
              G  G PG  GPPG  G PG  G+ G  GI G KG       +GE+G  G PGP     
Sbjct: 890  VIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISH 949

Query: 403  --------------GRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAG 448
                          G  G KG +G PG+PG +GL G+ G  G PG  G  G  G+PG  G
Sbjct: 950  VIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG 1009

Query: 449  L------------PGEKGEKGESGEPGPKGQ---------QGVRGEPGY--------PGP 479
            L            PG KG++G  G PG  G+         QG +GEPGY        PGP
Sbjct: 1010 LRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP 1069

Query: 480  SGDAGAP------GVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKML 533
            +GD G P      G  G PGPPG  G AG  G PG PG  G+ G+        D+  K  
Sbjct: 1070 TGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHG---DLGFK-- 1124

Query: 534  QEQLAEVAVSAKREALGAVGMMGPP---GPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQ 590
                            G  G++GPP   GPPG PG+PG  GP G  G +G  GI G  G+
Sbjct: 1125 ----------------GIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE 1168

Query: 591  IGNTG----PKGKRGEKGDPGEVG-RGHPGMPGPP------------------GIPGLPG 627
             G TG    P G RG  G  G  G RG PG PG P                  G PG PG
Sbjct: 1169 KGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPG 1228

Query: 628  RPGQAINGKDGDRGSPGAPGEAGRPGLPGPVG 659
             PG  I G+ G+RG PG+ G  G PG PGP G
Sbjct: 1229 LPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPG 1260



 Score =  409 bits (1051), Expect = e-114
 Identities = 238/525 (45%), Positives = 274/525 (52%), Gaps = 43/525 (8%)

Query: 27   GPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPD--------- 77
            G PG  GPPGPPG PG PG  G  G  G  G+ G PG KGE G  G  GP          
Sbjct: 895  GFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDK 954

Query: 78   GKPGIDGLTGAKGEPGPMGIPGV---KGQPGLPGPPGLPGP----GFAGPPGPPGPVGLP 130
            G+PG+ G  G  GE G  G+PG+   KG  GLPGP G PGP    G  G PG PG  G+P
Sbjct: 955  GEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIP 1014

Query: 131  GEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGT--IQGLEGSADFLCPTNC-PPGMKGPPG 187
            G +G  G  G  G  G  G PG  G+PG PG   +QG +G   +   T   PPG  G PG
Sbjct: 1015 GSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPG 1074

Query: 188  LQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQG---IRGYPGMAGPKG 244
            L G  G  G+ G  G PGH G  GP+G  G+ G  G+PG PGP G    +G  G+ GP G
Sbjct: 1075 LPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPG 1134

Query: 245  ETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPG 304
              GP G  G  G+ G  G  G++G  G PG AGEKG+ G   +R P G  G  GA G  G
Sbjct: 1135 IRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGL--LRAPPGPRGNPGAQGAKG 1192

Query: 305  INGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGT--KGGPGDQGEPGPQGLPGF 362
              G  G PG PG KG+ G AG  G  G +G  G PG PG    G  G++G PG +G PG 
Sbjct: 1193 DRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGA 1252

Query: 363  SGPPGKEGEP--GPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQ 420
             GPPG  G    G +G+ G  G  G KG  G  G +G PG  G  G  G  GP G PG Q
Sbjct: 1253 PGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQ 1312

Query: 421  GLPGVKGDKGSP------GKTGPRGKVGDPGVAG---------LPGEKGEKGESGEPGPK 465
            G PGVKG+KG+P      G  GP G  G PGV G         LPG  G  G  GEPG +
Sbjct: 1313 GFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQ 1372

Query: 466  GQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQP 510
            G+ G  G PG  GP G  G PG  G PG PGP G  GN+G  G+P
Sbjct: 1373 GEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEP 1417



 Score =  393 bits (1010), Expect = e-109
 Identities = 260/661 (39%), Positives = 321/661 (48%), Gaps = 105/661 (15%)

Query: 83  DGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDP 142
           DG  G KGE G  G PG  GQ G  GP GLPGP   GP G PG  GL G  G+RG  G P
Sbjct: 42  DGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGP--QGPKGFPGLPGLTGSKGVRGISGLP 99

Query: 143 GPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILG 202
           G  G  G PG PG  G  G + G+ G +          G +G PGL G  G+ G  G  G
Sbjct: 100 GFSGSPGLPGTPGNTGPYGLV-GVPGCSG-------SKGEQGFPGLPGTLGYPGIPGAAG 151

Query: 203 DPGHQGKPGPKGDV--GASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGA 260
             G +G P  + D+   A G+ G+PG PGPQG+ G PG  GP G  GP G+ G  GA+G 
Sbjct: 152 LKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGP 211

Query: 261 TGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQG-----ITGPKGAT---GPPGINGKDGTP 312
            GP G  G R   G  GE+G +G  G  GP G     +TGP   T   G  G  G  G P
Sbjct: 212 RGPKGHMGER-VIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEP 270

Query: 313 GTPGMKGSAGQA--GQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEG 370
           G PG  G  G++   + G+PG  GL G PG+ G  G PG +G  G +G PG  G  G +G
Sbjct: 271 GPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKG 330

Query: 371 EPGPRGEIGPQGIMG---------QKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQG 421
           +   +G+IGP G  G         +KGD+G  GP   PGP+G +GP+G  GPPG+PG  G
Sbjct: 331 Q---KGDIGPPGFRGPTEYYDTYQEKGDEGTPGP---PGPRGARGPQGPSGPPGVPGSPG 384

Query: 422 L--PGVKGDKGSPGKTGPRGKVGDPG-----VAGLPGEKGEKGESGEPGPKGQQGV---- 470
              PG++G  G PG  G +G+ G PG       G PG  G  G  G PGP G  G     
Sbjct: 385 SSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFR 444

Query: 471 RGEPGYPGPSGDAGAPGVQGYPGPPGPRGLA--------GNRGVPGQPGRQGVEGRDATD 522
           +G PG  G  G  G+PG+ G  GP G  GL         G  G+PG PG  GV+G     
Sbjct: 445 KGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKG----- 499

Query: 523 QHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVP 582
                              +  ++ A G  G  G PG  G PG+PG  G  G PG +G  
Sbjct: 500 -------------------IPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEK 540

Query: 583 G-IVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQ-AINGKDGDR 640
           G  +   GQ+G  G  G RG+ G      +G  G+PG PG+ GLPG  G+ A++G+ GD+
Sbjct: 541 GETLQPEGQVGVPGDPGLRGQPGR-----KGLDGIPGTPGVKGLPGPKGELALSGEKGDQ 595

Query: 641 G------SPGAPGEAG-----------RPGLPGPVGLPGFCEPAACLGASAYASARLTEP 683
           G      SPG+PG AG            PGL G  G+PG   P    G     S     P
Sbjct: 596 GPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVP 655

Query: 684 G 684
           G
Sbjct: 656 G 656



 Score =  335 bits (860), Expect = 6e-92
 Identities = 212/526 (40%), Positives = 262/526 (49%), Gaps = 78/526 (14%)

Query: 183 KGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGP 242
           KG     G KG  G++G    PG  G PG K   G +G +G+PGP GP+G  G PG+ G 
Sbjct: 36  KGQCFCDGAKGEKGEKGF---PGPPGSPGQK---GFTGPEGLPGPQGPKGFPGLPGLTGS 89

Query: 243 KGETGPHGYKGMVGAIGATGPPGEEGPR---GPPGRAGEKGDEGSPGIRGPQGITGPKGA 299
           KG  G  G  G  G+ G  G PG  GP    G PG +G KG++G PG+ G  G  G  GA
Sbjct: 90  KGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGA 149

Query: 300 TGPPGINGKDGTPGTPG--MKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQ 357
               G+ G+ G P         + G  G PG+PG QGL G PG PG  G PG        
Sbjct: 150 A---GLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGP------- 199

Query: 358 GLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGP---------------- 401
             PGF G PG  G  GP+G +G + ++G KG++G +G  G PGP                
Sbjct: 200 --PGFFGFPGAMGPRGPKGHMG-ERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTD 256

Query: 402 -QGRQGPKGEQGPPGIPGPQGLPGVK--GDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGE 458
            +G +G KG  G PG PGP GLPG     +KG+PG  G +GK G  GV G PG +G KG 
Sbjct: 257 LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN 316

Query: 459 SGEPGPKGQQGVRGEPGYPGPSGDAG---------APGVQGYPGPPGPRGLAGNR----- 504
            G PG  G+ G++G+ G  GP G  G           G +G PGPPGPRG  G +     
Sbjct: 317 RGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGP 376

Query: 505 -GVPGQPG--RQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPP 561
            GVPG PG  R G+ G            LK  + +         R    A+G  G PG  
Sbjct: 377 PGVPGSPGSSRPGLRGAPGWP------GLKGSKGERG-------RPGKDAMGTPGSPGCA 423

Query: 562 GPPGYPGKQGPHGHPGP----RGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMP 617
           G PG PG  GP G PG     +G PG  G  G +G+ G  G  G KG+PG +    P +P
Sbjct: 424 GSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIP 483

Query: 618 GPPGIPGLPGRPG-QAINGKDGDRGSPGAPGEAGRPGLPGPVGLPG 662
           GPPG+PGLPG  G + I G+ G  G  G+PG  G  GLPG  G PG
Sbjct: 484 GPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPG 529



 Score =  261 bits (668), Expect = 1e-69
 Identities = 159/372 (42%), Positives = 181/372 (48%), Gaps = 65/372 (17%)

Query: 26   RGPPG-----ERGPPGPPGPPGVPGSDGIDGDNG---PPGKAGPPGPKGEPGKAGPDGPD 77
            +G PG       GPPGP G PG+PG  G  G+ G   PPG  GP GP+G PG  G  G  
Sbjct: 1053 KGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLP 1112

Query: 78   GKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP----GFAGPPGPPGPVGLPGEI 133
            GKPG  G  G KG  G +G PG++G PGLPG PG PGP    G  G  G PGP G  GE 
Sbjct: 1113 GKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGET 1172

Query: 134  GIR----GPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNC----------- 178
            G+     GP+G+PG  G  G  G PG PG PG  +G  G A    PT             
Sbjct: 1173 GLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGR-KGAMGDAGPRGPTGIEGFPGPPGLPG 1231

Query: 179  -----------PPGMKGPPGLQGVKGHAGKR--GILGDPGHQGKPGPKGDVGASGEQG-- 223
                       PPG +G PG  G  G  G    GI GD G  G PGPKG  G +G+ G  
Sbjct: 1232 AIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPP 1291

Query: 224  -------IPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRG----- 271
                    PG PGP+G  G+ G  G KGE G  G+ G +G  G  GP G  G RG     
Sbjct: 1292 GRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTL 1351

Query: 272  ----------PPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSA 321
                      PPG  GE G +G PG  GP G  GP G  G PG +GK GTPG  G KG+ 
Sbjct: 1352 KIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNK 1411

Query: 322  GQAGQPGSPGHQ 333
            G  G+P S  HQ
Sbjct: 1412 GSKGEPESLFHQ 1423



 Score =  141 bits (355), Expect = 2e-33
 Identities = 74/151 (49%), Positives = 85/151 (56%), Gaps = 16/151 (10%)

Query: 25   IRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDG 84
            I+G  G  G PGP GPPG  G  G  G  G PG  G PGP+G+PG  G  G  G+ G  G
Sbjct: 1266 IKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG 1325

Query: 85   LTGAKGEPGPM---GIPGVKGQPGL---------PGPPGLPG-PGFAGPPGPPGPVGLPG 131
              G+ G PGP+   G PGV+G PG          PGPPG PG PG  G PGPPGP   PG
Sbjct: 1326 FLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGP---PG 1382

Query: 132  EIGIRGPKGDPGPDGPSGPPGPPGKPGRPGT 162
             +G  GP+G PG DG  G PGP G+ G  G+
Sbjct: 1383 NLGPCGPRGKPGKDGKPGTPGPAGEKGNKGS 1413


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.146    0.470 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,551,103
Number of Sequences: 37866
Number of extensions: 5425789
Number of successful extensions: 239820
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 600
Number of HSP's successfully gapped in prelim test: 1619
Number of HSP's that attempted gapping in prelim test: 16351
Number of HSP's gapped (non-prelim): 26440
length of query: 689
length of database: 18,247,518
effective HSP length: 109
effective length of query: 580
effective length of database: 14,120,124
effective search space: 8189671920
effective search space used: 8189671920
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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