BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Homo sapiens] (1516 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Ho... 3222 0.0 gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho... 2781 0.0 gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Ho... 2776 0.0 gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens] 777 0.0 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 552 e-156 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 547 e-155 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 545 e-154 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 543 e-154 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 541 e-153 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 540 e-153 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 536 e-152 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 533 e-151 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 533 e-151 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 533 e-151 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 530 e-150 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 530 e-150 gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 528 e-149 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 527 e-149 gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 524 e-148 gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 523 e-148 gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 523 e-148 gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 514 e-145 gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 514 e-145 gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 512 e-144 gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 512 e-144 gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 512 e-144 gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 512 e-144 gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 504 e-142 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 504 e-142 gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 490 e-138 >gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Homo sapiens] Length = 1516 Score = 3222 bits (8354), Expect = 0.0 Identities = 1516/1516 (100%), Positives = 1516/1516 (100%) Query: 1 MAPYPCGCHILLLLFCCLAAARANLLNLNWLWFNNEDTSHAATTIPEPQGPLPVQPTADT 60 MAPYPCGCHILLLLFCCLAAARANLLNLNWLWFNNEDTSHAATTIPEPQGPLPVQPTADT Sbjct: 1 MAPYPCGCHILLLLFCCLAAARANLLNLNWLWFNNEDTSHAATTIPEPQGPLPVQPTADT 60 Query: 61 TTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEENIAGVGAEILNVAKG 120 TTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEENIAGVGAEILNVAKG Sbjct: 61 TTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEENIAGVGAEILNVAKG 120 Query: 121 IRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSPGA 180 IRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSPGA Sbjct: 121 IRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSPGA 180 Query: 181 HTTEAGTLPAPTPSPPSLGRPWAPLTGPSVPPPSSERISEEVGLLQLLGDPPPQQVTQTD 240 HTTEAGTLPAPTPSPPSLGRPWAPLTGPSVPPPSSERISEEVGLLQLLGDPPPQQVTQTD Sbjct: 181 HTTEAGTLPAPTPSPPSLGRPWAPLTGPSVPPPSSERISEEVGLLQLLGDPPPQQVTQTD 240 Query: 241 DPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVL 300 DPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVL Sbjct: 241 DPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVL 300 Query: 301 LGVKLSGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDC 360 LGVKLSGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDC Sbjct: 301 LGVKLSGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDC 360 Query: 361 EEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEE 420 EEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEE Sbjct: 361 EEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEE 420 Query: 421 GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 480 GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE Sbjct: 421 GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 480 Query: 481 EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSP 540 EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSP Sbjct: 481 EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSP 540 Query: 541 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG 600 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG Sbjct: 541 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG 600 Query: 601 PQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDL 660 PQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDL Sbjct: 601 PQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDL 660 Query: 661 EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP 720 EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP Sbjct: 661 EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP 720 Query: 721 GPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPP 780 GPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPP Sbjct: 721 GPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPP 780 Query: 781 GPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADG 840 GPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADG Sbjct: 781 GPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADG 840 Query: 841 VPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDG 900 VPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDG Sbjct: 841 VPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDG 900 Query: 901 SVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQ 960 SVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQ Sbjct: 901 SVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQ 960 Query: 961 KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPG 1020 KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPG Sbjct: 961 KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPG 1020 Query: 1021 PPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFD 1080 PPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFD Sbjct: 1021 PPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFD 1080 Query: 1081 FLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESI 1140 FLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESI Sbjct: 1081 FLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESI 1140 Query: 1141 RGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGT 1200 RGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGT Sbjct: 1141 RGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGT 1200 Query: 1201 MGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGT 1260 MGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGT Sbjct: 1201 MGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGT 1260 Query: 1261 DNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSY 1320 DNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSY Sbjct: 1261 DNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSY 1320 Query: 1321 VHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFR 1380 VHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFR Sbjct: 1321 VHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFR 1380 Query: 1381 AFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKD 1440 AFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKD Sbjct: 1381 AFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKD 1440 Query: 1441 VLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHH 1500 VLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHH Sbjct: 1441 VLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHH 1500 Query: 1501 AYIVLCIENSFMTASK 1516 AYIVLCIENSFMTASK Sbjct: 1501 AYIVLCIENSFMTASK 1516 >gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo sapiens] Length = 1751 Score = 2781 bits (7209), Expect = 0.0 Identities = 1309/1331 (98%), Positives = 1313/1331 (98%), Gaps = 5/1331 (0%) Query: 186 GTLPAPTPSPPSLGRPWAPLTGPSVPPPSSERISEEVGLLQLLGDPPPQQVTQTDDPDVG 245 G LP S P+ + L GP+ +ERISEEVGLLQLLGDPPPQQVTQTDDPDVG Sbjct: 426 GRLPVACASLPTQEDGYCVLIGPA-----AERISEEVGLLQLLGDPPPQQVTQTDDPDVG 480 Query: 246 LAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKL 305 LAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKL Sbjct: 481 LAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKL 540 Query: 306 SGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQR 365 SGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQR Sbjct: 541 SGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQR 600 Query: 366 MPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSD 425 MPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSD Sbjct: 601 MPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSD 660 Query: 426 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 485 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV Sbjct: 661 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 720 Query: 486 ASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGP 545 ASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGP Sbjct: 721 ASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGP 780 Query: 546 PGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFP 605 PGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFP Sbjct: 781 PGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFP 840 Query: 606 GTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRG 665 GTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRG Sbjct: 841 GTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRG 900 Query: 666 PRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGR 725 PRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGR Sbjct: 901 PRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGR 960 Query: 726 EGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGP 785 EGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGP Sbjct: 961 EGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGP 1020 Query: 786 GLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFP 845 GLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFP Sbjct: 1021 GLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFP 1080 Query: 846 GLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSV 905 GLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSV Sbjct: 1081 GLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSV 1140 Query: 906 PGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKG 965 PGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKG Sbjct: 1141 PGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKG 1200 Query: 966 EPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPP 1025 EPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPP Sbjct: 1201 EPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPP 1260 Query: 1026 GPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLE 1085 GPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLE Sbjct: 1261 GPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLE 1320 Query: 1086 AEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPG 1145 AEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPG Sbjct: 1321 AEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPG 1380 Query: 1146 PPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASS 1205 PPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASS Sbjct: 1381 PPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASS 1440 Query: 1206 GVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVA 1265 GVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVA Sbjct: 1441 GVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVA 1500 Query: 1266 ALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRP 1325 ALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRP Sbjct: 1501 ALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRP 1560 Query: 1326 ARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAFLSS 1385 ARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAFLSS Sbjct: 1561 ARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAFLSS 1620 Query: 1386 RLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHP 1445 RLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHP Sbjct: 1621 RLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHP 1680 Query: 1446 TWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHHAYIVL 1505 TWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHHAYIVL Sbjct: 1681 TWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHHAYIVL 1740 Query: 1506 CIENSFMTASK 1516 CIENSFMTASK Sbjct: 1741 CIENSFMTASK 1751 Score = 460 bits (1184), Expect = e-129 Identities = 227/243 (93%), Positives = 227/243 (93%), Gaps = 6/243 (2%) Query: 1 MAPYPCGCHILLLLFCCLAAARANLLNLNWLWFNNEDTSHAATTIPEPQGPLPVQPTADT 60 MAPYPCGCHILLLLFCCLAAARANLLNLNWLWFNNEDTSHAATTIPEPQGPLPVQPTADT Sbjct: 1 MAPYPCGCHILLLLFCCLAAARANLLNLNWLWFNNEDTSHAATTIPEPQGPLPVQPTADT 60 Query: 61 TTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEENIAGVGAEILNVAKG 120 TTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEENIAGVGAEILNVAKG Sbjct: 61 TTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEENIAGVGAEILNVAKG 120 Query: 121 IRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSPGA 180 IRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSPGA Sbjct: 121 IRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSPGA 180 Query: 181 HTTEAGTLPAPTPSPPSLGRPWAPLTGPSVPPPSSERISEEVGLLQLLGDPPPQQVTQTD 240 HTTEAGTLPAPTPSPPSLGRPWAPLTGPSVPPPSS R S L LLG PP Q Sbjct: 181 HTTEAGTLPAPTPSPPSLGRPWAPLTGPSVPPPSSGRAS----LSSLLGGAPPWGSLQ-- 234 Query: 241 DPD 243 DPD Sbjct: 235 DPD 237 Score = 37.0 bits (84), Expect = 0.15 Identities = 74/301 (24%), Positives = 93/301 (30%), Gaps = 45/301 (14%) Query: 561 ALQTVPGPQGP-PGPPGRDGT---------------PGRDGEPGDPGEDGKPGDTGPQGF 604 A T+P PQGP P P D T PG P + EDG+ T + Sbjct: 41 AATTIPEPQGPLPVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAES- 99 Query: 605 PGTPGD--VGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEA 662 P P + G + + G R P R + L G A Sbjct: 100 PDAPEENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGP------LA 153 Query: 663 LRGPRGFPGPPGPPGVP--GLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP 720 L GP P G P G+P PG + +P P P GR P L GP Sbjct: 154 LAGPSSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWAP----LTGPS 209 Query: 721 GPPGREGPP------GRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGA---PGPA 771 PP G G GSL + + G + AP R + L P Sbjct: 210 VPPPSSGRASLSSLLGGAPPWGSLQDPDSQGLSPAAAAPSQQLQRPDVRLRTPLLHPLVM 269 Query: 772 GPPGPPGPPGPPGPGLPAGFDD-----MEGSGGPFWSTARSADGPQGPPGLPGLKGDPGV 826 G G P GLP + G + S ++ GP L DP Sbjct: 270 GSLGKHAAPSAFSSGLPGALSQVAVTTLTRDSGAWVSHVANSVGPGLANNSALLGADPEA 329 Query: 827 P 827 P Sbjct: 330 P 330 Score = 33.5 bits (75), Expect = 1.6 Identities = 85/361 (23%), Positives = 106/361 (29%), Gaps = 51/361 (14%) Query: 446 TGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVST---- 501 T A P P PP + L G T S + +A +GA+ L + + + Sbjct: 71 TEPATAPGSPEPP---SELLEDGQDTPTSAESPDAPEENIAGVGAEILNVAKGIRSFVQL 127 Query: 502 WDGSVRTPGGRVKEGGLKGQKGEPGVP-GPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP 560 W+ +V T E + + P GP AGP +P G P P P Sbjct: 128 WNDTVPT------ESLARAETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSPGAH 181 Query: 561 ALQTVPGPQGPPGPPGRDGTPGRDGEPGDP--GEDGKPGDTGPQGFPGTPGDVGPKGDKG 618 + P P PP G P P G P +G G P G Sbjct: 182 TTEAGTLPAPTPSPPSL-------GRPWAPLTGPSVPPPSSGRASLSSLLGGAPPWGSLQ 234 Query: 619 DPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGV 678 DP P P R + G G PG V Sbjct: 235 DPDSQGLSPAAAAPSQQLQRPDVRLRTPLLHPLVMGSLGKHAAPSAFSSGLPGALSQVAV 294 Query: 679 PGLPGEPGRF--GVNSSDVPGPAGLPGVPGR--EGPPGFPGLPGPPGPPGREGPPGRTGQ 734 L + G + V +S PG A + G E P G LP PP P G G Sbjct: 295 TTLTRDSGAWVSHVANSVGPGLANNSALLGADPEAPAG-RCLPLPPSLP----VCGHLG- 348 Query: 735 KGSLGEAGAPGH-KGSKGAPGPAGARGESGLAGA--------------PGPAGPPGPPGP 779 + P H G AGAR GL P G PP P Sbjct: 349 ---ISRFWLPNHLHHESGEQVRAGARAWGGLLQTHCHPFLAWFFCLLLVPPCGSVPPPAP 405 Query: 780 P 780 P Sbjct: 406 P 406 Score = 33.1 bits (74), Expect = 2.1 Identities = 49/183 (26%), Positives = 60/183 (32%), Gaps = 31/183 (16%) Query: 41 AATTIPEPQGPLPVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAES- 99 A T+P PQGP P P D T PG P + EDG+ T + Sbjct: 796 ALQTVPGPQGP-PGPPGRDGT---------------PGRDGEPGDPGEDGKPGDTGPQGF 839 Query: 100 PDAPEENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGP------LA 153 P P + G + + G R P R + L G A Sbjct: 840 PGTPGD--VGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEA 897 Query: 154 LAGPSSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWAP----LTGPS 209 L GP P G P G+P PG + +P P P GR P L GP Sbjct: 898 LRGPRGFPGPPGPPGVP--GLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP 955 Query: 210 VPP 212 PP Sbjct: 956 GPP 958 Score = 32.3 bits (72), Expect = 3.6 Identities = 74/299 (24%), Positives = 95/299 (31%), Gaps = 56/299 (18%) Query: 769 GPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGP-PGLPGLKGDPGVP 827 G P PG P PP L G D T SA+ P P + G+ G Sbjct: 69 GSTEPATAPGSPEPPSELLEDGQD-----------TPTSAESPDAPEENIAGV----GAE 113 Query: 828 GLPGAKG-----EVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGL 882 L AKG ++ D VP L E + + P G G P ++G Sbjct: 114 ILNVAKGIRSFVQLWNDTVP-TESLARAETLV-LETPVGPLALAGPSSTPQENGTTLWPS 171 Query: 883 PGPPGPPGPVVYVSEQDGSVLSVPGPE--GRPGFAGFPGPAGPKGNLGSKGERGSPGPKG 940 G P PG + +E P P GRP +A GP+ P S G G Sbjct: 172 RGIPSSPG--AHTTEAGTLPAPTPSPPSLGRP-WAPLTGPSVPP---PSSGRASLSSLLG 225 Query: 941 EKGEPGSIFSPDGGALGPAQKGAKGE--------------PGFRGPPGPYGRPGYKGEIG 986 GS+ PD L PA + P G G + P G Sbjct: 226 GAPPWGSLQDPDSQGLSPAAAAPSQQLQRPDVRLRTPLLHPLVMGSLGKHAAPSAFSS-G 284 Query: 987 FPGRPGRPGMNGLKGEKGE----------PGDASLGFGMRGMPGPPGPPGPPGPPGTPV 1035 PG + + L + G PG A+ + P P P PP PV Sbjct: 285 LPGALSQVAVTTLTRDSGAWVSHVANSVGPGLANNSALLGADPEAPAGRCLPLPPSLPV 343 >gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Homo sapiens] Length = 1336 Score = 2776 bits (7197), Expect = 0.0 Identities = 1304/1316 (99%), Positives = 1304/1316 (99%) Query: 201 PWAPLTGPSVPPPSSERISEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVA 260 P L G ERISEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVA Sbjct: 21 PLVLLLGVRAASAEPERISEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVA 80 Query: 261 RYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYT 320 RYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYT Sbjct: 81 RYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYT 140 Query: 321 EPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPG 380 EPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPG Sbjct: 141 EPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPG 200 Query: 381 AGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSGLGDARE 440 AGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSGLGDARE Sbjct: 201 AGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSGLGDARE 260 Query: 441 LLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVS 500 LLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVS Sbjct: 261 LLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVS 320 Query: 501 TWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP 560 TWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP Sbjct: 321 TWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP 380 Query: 561 ALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDP 620 ALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDP Sbjct: 381 ALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDP 440 Query: 621 GVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPG 680 GVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPG Sbjct: 441 GVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPG 500 Query: 681 LPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGE 740 LPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGE Sbjct: 501 LPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGE 560 Query: 741 AGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGP 800 AGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGP Sbjct: 561 AGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGP 620 Query: 801 FWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPK 860 FWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPK Sbjct: 621 FWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPK 680 Query: 861 GDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGP 920 GDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGP Sbjct: 681 GDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGP 740 Query: 921 AGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPG 980 AGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPG Sbjct: 741 AGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPG 800 Query: 981 YKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNV 1040 YKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNV Sbjct: 801 YKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNV 860 Query: 1041 FAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQ 1100 FAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQ Sbjct: 861 FAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQ 920 Query: 1101 KGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGR 1160 KGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGR Sbjct: 921 KGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGR 980 Query: 1161 QGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQV 1220 QGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQV Sbjct: 981 QGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQV 1040 Query: 1221 HEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPY 1280 HEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPY Sbjct: 1041 HEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPY 1100 Query: 1281 PRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSHRDFQ 1340 PRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSHRDFQ Sbjct: 1101 PRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSHRDFQ 1160 Query: 1341 PVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRA 1400 PVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRA Sbjct: 1161 PVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRA 1220 Query: 1401 AVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNG 1460 AVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNG Sbjct: 1221 AVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNG 1280 Query: 1461 RRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK 1516 RRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK Sbjct: 1281 RRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK 1336 Score = 33.1 bits (74), Expect = 2.1 Identities = 49/183 (26%), Positives = 60/183 (32%), Gaps = 31/183 (16%) Query: 41 AATTIPEPQGPLPVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAES- 99 A T+P PQGP P P D T PG P + EDG+ T + Sbjct: 381 ALQTVPGPQGP-PGPPGRDGT---------------PGRDGEPGDPGEDGKPGDTGPQGF 424 Query: 100 PDAPEENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGP------LA 153 P P + G + + G R P R + L G A Sbjct: 425 PGTPGD--VGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEA 482 Query: 154 LAGPSSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWAP----LTGPS 209 L GP P G P G+P PG + +P P P GR P L GP Sbjct: 483 LRGPRGFPGPPGPPGVP--GLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP 540 Query: 210 VPP 212 PP Sbjct: 541 GPP 543 >gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens] Length = 1388 Score = 777 bits (2007), Expect = 0.0 Identities = 533/1466 (36%), Positives = 688/1466 (46%), Gaps = 253/1466 (17%) Query: 204 PLTGPSVPPPSSERISE-EVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVARY 262 PL + ++E S+ + L QL+G P P V+ AY FGP AN G+ AR Sbjct: 22 PLPAVTQTRGATETASQGHLDLTQLIGVPLPSSVSFVTGYGGFPAYSFGPGANVGRPART 81 Query: 263 HFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYTEP 322 PS FFRDF++ ++P++ GVLFAITD+ Q ++ LG++LSGV+DGHQ I L YTEP Sbjct: 82 LIPSTFFRDFAISVVVKPSSTRGGVLFAITDAFQKVIYLGLRLSGVEDGHQRIILYYTEP 141 Query: 323 GAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPGAG 382 G+ + AA+F +P +W A+ V G V L V+CEE R+P RSS+ L E AG Sbjct: 142 GSHVSQEAAAFSVPVMTHRWNRFAMIVQGEEVTLLVNCEEHSRIPFQRSSQALAFESSAG 201 Query: 383 LFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSGLGDA---R 439 +F+ AG ++F G + +L V DP+ C EE ASG++ SGL +A Sbjct: 202 IFMGNAGATGLERFTGSLQQLTVHPDPRTPEELCDPEESS----ASGET-SGLQEADGVA 256 Query: 440 ELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSV 499 E+L T P+ P+ TPP + S E + T+ + + S Sbjct: 257 EILEAVTYTQASPKEAKVEPINTPPTPSSPFEDMELSGEPVPEGTLETTNMSIIQHS--- 313 Query: 500 STWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVS-----P 554 S + G + L+G G P +G + L + P Sbjct: 314 -----SPKQGSGEILNDTLEGVHSVDGDPITDSGSGAGAFLDIAEEKNLAATAAGLAEVP 368 Query: 555 LGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG--PQGFPGTPGDVG 612 + AG A + P G P P PG E+ + PG+V Sbjct: 369 ISTAGEA-EASSVPTGGPTLSMSTENPEEGVTPGPDNEERLAATAAGEAEALASMPGEVE 427 Query: 613 PKG--------DKGDPGVGERGPPGPQGPPG--PPGPSFRHDKLTFIDMEGSGFGGD--- 659 G +GE GP + TF D E SG D Sbjct: 428 ASGVAPGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEASGVPTDGLA 487 Query: 660 -LEALRGPR------------------------------GFPGPPGPPGVPGLPGEPGRF 688 L A P G P P GPP +P P R+ Sbjct: 488 PLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPDGPP-LPLPTVAPERW 546 Query: 689 GVNSSDVPGPAGLPGVPGREGPPGFPG-----LPGPPGPPGREGPPGRTGQKGSLGEAGA 743 P G+ G+ GP G G LPGPP P G GP +GS G+ Sbjct: 547 -----ITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGS 601 Query: 744 PGHKGS----------KGAPGPAGARGESGLAGAPG------PAGPPGPPGPPGPPGPGL 787 GS +G PGP G G G+ G PG P G PG GP G PGP Sbjct: 602 DVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPG 661 Query: 788 PAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGL 847 P G ++G+ G + G +GP G G KGDPG GLPG G+ G G PG G Sbjct: 662 PEGQPGVDGATG--LPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGP 719 Query: 848 PGREGIAGPQGP----------------------------------KGDRGSRGEKGDPG 873 PG G GP GP KG++G RG KG+ G Sbjct: 720 PGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERG 779 Query: 874 KDGVGQPGLPGPPGPPGPVVYVSEQDGSV-------------LSVPGPEGRPGFAGFPGP 920 DG G PGP GPPG + +S ++ + PGP+G PG GFPGP Sbjct: 780 MDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGP 839 Query: 921 AGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQK--GAKGEPGFRGPPGPYGR 978 GPKG+ G G G G +GEKGEPG+I + D P ++ G KGEPG G PGP G Sbjct: 840 RGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDI----PLERLMGKKGEPGMHGAPGPMGP 895 Query: 979 ---PGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPV 1035 PG+KGE G PGRPGRPG+NGLKG KG+PG M+G PG PGPPGPPGPPG + Sbjct: 896 KGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVI-----MQGPPGLPGPPGPPGPPGAVI 950 Query: 1036 YDSNVF------------AESSRPGPP---------GLPGNQGPPGPKGAKGEVGPPGPP 1074 +++ PG P G G+ G PG KG KG+ G GPP Sbjct: 951 NIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPP 1010 Query: 1075 GQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPG--GGGFFGSSLPGPPGPPGPRGYPG- 1131 G P D L + KG+ GD G KGE+GE G G F S PG PG PGP G G Sbjct: 1011 GP-PLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGE 1069 Query: 1132 -IPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPG 1190 + GP+G PG PG GPPG G G GPPGPPGPPGPP+ G +++PGPPG Sbjct: 1070 TVVGPQGP-----PGAPGLPGPPGFGRPGDPGPPGPPGPPGPPAILGA---AVALPGPPG 1121 Query: 1191 PPGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQL 1250 PPG PG PG+ V ++ ML + H V EG I++ + E ++RV++G++K+QL Sbjct: 1122 PPGQPGLPGSRNL---VTAFSNMDDMLQKAHLVIEGTFIYLRDSTEFFIRVRDGWKKLQL 1178 Query: 1251 EARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQP 1310 P+P A PP L SNP+ LP P P Sbjct: 1179 GELIPIP--------ADSPPPPAL-SSNPHQL----------------------LPPPNP 1207 Query: 1311 YPGAPHHSSYVHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQA 1370 A + +P LHL ALN P SG +R ADFQCF+QA Sbjct: 1208 ISSANYE----------------------KPALHLAALNMPFSGDIR----ADFQCFKQA 1241 Query: 1371 RAVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPG 1430 RA GL T+RAFLSS LQDL +IVR+A+R ++PIVNLK ++LF +W+++FSG G Sbjct: 1242 RAAGLLSTYRAFLSSHLQDLSTIVRKAERYSLPIVNLKGQVLFNNWDSIFSGHGGQFNMH 1301 Query: 1431 ARIFSFDGKDVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRL 1490 I+SFDG+D++ P+WPQK +WHGS P+G RL ++YCE WRT + TG AS L G++ Sbjct: 1302 IPIYSFDGRDIMTDPSWPQKVIWHGSSPHGVRLVDNYCEAWRTADTAVTGLASPLSTGKI 1361 Query: 1491 LGQSAASCHHAYIVLCIENSFMTASK 1516 L Q A SC + IVLCIENSFMT ++ Sbjct: 1362 LDQKAYSCANRLIVLCIENSFMTDAR 1387 Score = 32.3 bits (72), Expect = 3.6 Identities = 21/63 (33%), Positives = 25/63 (39%), Gaps = 14/63 (22%) Query: 150 GPLALAGPSSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWAPLTGPS 209 GP L G + G T+ +G P +PG P PP GRP P GP Sbjct: 1053 GPPGLPGNPGPAGQKGETVVGPQGPPGAPG------------LPGPPGFGRPGDP--GPP 1098 Query: 210 VPP 212 PP Sbjct: 1099 GPP 1101 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 552 bits (1422), Expect = e-156 Identities = 392/966 (40%), Positives = 433/966 (44%), Gaps = 216/966 (22%) Query: 426 GASGDSGSG--------------LGDARELLREETGAALKPRLPAPPPVTTPPLAGGSST 471 G GD+GS L AR LR G P P PP +GG Sbjct: 527 GGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGP---VGPPGSGGLKG 583 Query: 472 EDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--------GLKGQKG 523 E + G PG + DG+ PG +G GL G+KG Sbjct: 584 EPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKG 643 Query: 524 EPGVPGPPGRAGPPGS---------------PCLPGPPGLPCPVSPLGPAGP----ALQT 564 G PGP G GPPG P PGP GL P P GP GP + Sbjct: 644 HRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDG 703 Query: 565 VPGP------QGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKG 618 PGP QG PGPPG+ G PG G PG G G PG+ GP G PG PG G G G Sbjct: 704 QPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPG 763 Query: 619 DPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS----------GFGGDLE 661 PG G +GPPGPQGP G PGP ++G+ GF GD+ Sbjct: 764 HPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDM- 822 Query: 662 ALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP----------GPAGLPGVPGREGP- 710 ++G RG GPPGP G G G GR G N P G GLPG PGR+GP Sbjct: 823 GIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPK 882 Query: 711 -----PGFPGL---------PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPA 756 PGFPG PG PGP G+ GP G G++G G G PG KG+ G GPA Sbjct: 883 GSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPA 942 Query: 757 GARGESGLAGAPGPAGPPGPPGPPGPPG----PGLP-----AGFDDMEGSGGPFWSTA-- 805 G GE G G GP G PGP GPPGPPG PG P GF G GP Sbjct: 943 GPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQ 1002 Query: 806 -----------RSADGPQGPP---GLPGL------KGDPGVPGLPGAKGEVGADGVPGFP 845 R GP GPP GLPGL KGDPG GLPG G G G PG Sbjct: 1003 GPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDR 1062 Query: 846 GLP------GREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQ 898 GLP G +G GP GP G GS GE+G G G +G PG PGP GPPGP E+ Sbjct: 1063 GLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGP---AGEK 1119 Query: 899 DGSVLSVP-GPEGRPGF---AGFPGPAGP---------KGNLGSKGERGSPGPKGEKGEP 945 P GP GR G G PGPAGP KG +G G++GS G KGE+G P Sbjct: 1120 GAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPP 1179 Query: 946 GSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGL---KGE 1002 G P G P GA GEPG RG G +G+ G +G GFPG PG G+ GL GE Sbjct: 1180 GPT-GPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGE 1238 Query: 1003 KGEPGDASLGFGMRGMPGPPGPPGPPGPPGTP--------VYDSNVFAESSRP---GPPG 1051 KGE GD G G PGPPGP GP G PG + + E P G PG Sbjct: 1239 KGETGDV----GQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPG 1294 Query: 1052 LPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGG 1111 LPG GPPGPKG +GE G GP G G G +G G G +G PG G Sbjct: 1295 LPGEGGPPGPKGERGEKGESGPSG------------AAGPPGPKGPPGDDGPKGSPGPVG 1342 Query: 1112 FFGSSLPGPPGPPGPRGYPGIPGPKGE----SIRGQPGP---PGPQGPPG-------IGY 1157 F G PGPPG PGP G G PG KG+ G PGP PGP GPPG G Sbjct: 1343 FPGD--PGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGP 1400 Query: 1158 EGRQ------------GPP---GPPGPPGPPSFPGPHRQTISVPGP------PGPPGPPG 1196 EGRQ GPP GP GP G P PGP +PGP PG PGP G Sbjct: 1401 EGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLR-GIPGPVGEQGLPGSPGPDG 1459 Query: 1197 PPGTMG 1202 PPG MG Sbjct: 1460 PPGPMG 1465 Score = 529 bits (1363), Expect = e-150 Identities = 375/945 (39%), Positives = 425/945 (44%), Gaps = 164/945 (17%) Query: 373 RGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSD-GASGDS 431 RGL EPG + G P GV D Q P + +G+ G G+ Sbjct: 672 RGLPGEPGPRGLLGPKGPPGPPGPPGVTG-----MDGQPGPKGNVGPQGEPGPPGQQGNP 726 Query: 432 GS-GLGDARELLRE--ETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASL 488 G+ GL + + E G KP LP P PP G ++ E Q Sbjct: 727 GAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPP---GHPGKEGPPGEKGGQGPPGPQ 783 Query: 489 GAQTLPGSDSVSTWDGSVRTPGGRVKEG-----------GLKGQKGEPGVPGPPGRAGPP 537 G PG V DG G + ++G G+KG +GE G PGP G GP Sbjct: 784 GPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPE 843 Query: 538 GSPCLPGPPGLPCPVSPLGPAG----PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGED 593 G GP G P P+ P G G P L PG QGP G G G PG +GE G G Sbjct: 844 GPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTP 903 Query: 594 GKPGDTGPQGFPGTPGDVGPKGDKGDPGV-------------GERGPPGPQGPPG----- 635 GKPG G +G G G+ GP+G G PG GERGP GPQGP G Sbjct: 904 GKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPK 963 Query: 636 -PPGPSFRHDKLTFIDMEG-SGFGGDL-----------------EALRGPRGFPGPPGPP 676 PPGP + G +GF G G RG PGPPGPP Sbjct: 964 GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPP 1023 Query: 677 GVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKG 736 G GLPG G+ G PGPAGLPG ++GPPG G PG G PG P G G KG Sbjct: 1024 GEQGLPGLAGKEGTKGD--PGPAGLPG---KDGPPGLRGFPGDRGLPG---PVGALGLKG 1075 Query: 737 SLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG---PGLPAGFDD 793 + G G PG GS G GPAGA G G+ G PGP GPPGP G G PG P PAG D Sbjct: 1076 NEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1135 Query: 794 MEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPG------L 847 ++G G GP GPPG G KG+ G PG G+KG+ G G PG G Sbjct: 1136 LQGPVG-----LPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQ 1190 Query: 848 PGREGIAGPQGPKGDRGSRGEKGDPGKDG-------VGQPGLPGPPGPPGPVVYVSEQDG 900 PG G G GP+G +G G+KGD G G VG GLPGPPG G V + Sbjct: 1191 PGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGP 1250 Query: 901 SVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGP-- 958 PGP G G G GP GP G +G+ G G G GE GEPG +GG GP Sbjct: 1251 P--GPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPG--LPGEGGPPGPKG 1306 Query: 959 --AQKGAKGEPGFRGPPGPYGRPG------YKGEIGFPGRPGRPGMNGLKGEKGEPGDAS 1010 +KG G G GPPGP G PG G +GFPG PG PG G G+ G PGD Sbjct: 1307 ERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKG 1366 Query: 1011 LGF--GMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEV 1068 G G PGP G PGP GPPG + GPPG G +G G KGAKGE Sbjct: 1367 DDGEPGQTGSPGPTGEPGPSGPPG-------------KRGPPGPAGPEGRQGEKGAKGEA 1413 Query: 1069 GPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRG 1128 G GPPG+ Q G G RG G GE+G PG PGP GPPGP G Sbjct: 1414 GLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGS--------PGPDGPPGPMG 1465 Query: 1129 YPGIPGPKGES-------------------------IRGQPGPPGPQGPPGI-GYEGRQG 1162 PG+PG KG+S RG PGP G GP G G G G Sbjct: 1466 PPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSG 1525 Query: 1163 PPGPPGPPGPPSFPGPH--RQTISVPGP------PGPPGPPGPPG 1199 P GPPGPPG P PGP + + GP PGPPGPPGPPG Sbjct: 1526 PIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPG 1570 Score = 512 bits (1319), Expect = e-145 Identities = 327/744 (43%), Positives = 373/744 (50%), Gaps = 94/744 (12%) Query: 487 SLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSPCLPG 544 S+G PG++ G+ PG R + G G +G++G G+ G PG G G G Sbjct: 884 SIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAG 943 Query: 545 PPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGF 604 PPG P P GP G PGP+GPPGPPG+DG PG PG GE G G TGP Sbjct: 944 PPGERGPNGPQGPTG-----FPGPKGPPGPPGKDGLPGH---PGQRGETGFQGKTGP--- 992 Query: 605 PGTPGDVGPKGDKGDPG-VGERGPPGPQGPPGPPG-PSFRHDKLTFIDMEGSGFGGD--- 659 PG PG VGP+G G+ G +GERG PGP GPPG G P + T D +G G Sbjct: 993 PGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGP 1052 Query: 660 --LEALRGPRGFPGP---------PGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGRE 708 L G RG PGP GPPG PG G PG G + GP G+PG PG + Sbjct: 1053 PGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERG--PAGAAGPIGIPGRPGPQ 1110 Query: 709 GPPG------FPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA---PGPAGAR 759 GPPG PG GP GP GR+G G G G G G PG G KG PG G++ Sbjct: 1111 GPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSK 1170 Query: 760 GESGLAGAPGPAGPPGPPGPPGP------PGPGLPAGFDDMEGSGGPFWSTARSADGPQG 813 G+ G G PGP GP GP G PGP PGP G +G GP R GP G Sbjct: 1171 GDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGP-----RGFPGPPG 1225 Query: 814 PPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKG---DRGSRGEKG 870 P GL GL G PG G G G++G G PG G G G GPQGP G + G+ GEKG Sbjct: 1226 PVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKG 1285 Query: 871 DPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSK 930 +PG+ G+PGLPG GPPGP G +G G +G GP GPKG G Sbjct: 1286 EPGE--AGEPGLPGEGGPPGPK-----------GERGEKGESGPSGAAGPPGPKGPPGDD 1332 Query: 931 GERGSPGPKGEKGEPGSIFSPD--GGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFP 988 G +GSPGP G G+PG P G P KG GEPG G PGP G PG G G Sbjct: 1333 GPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKR 1392 Query: 989 GRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPG 1048 G PG G G +GEKG G+A G+ G PG GP GP G PG P D PG Sbjct: 1393 GPPGPAGPEGRQGEKGAKGEA----GLEGPPGKTGPIGPQGAPGKPGPDGL----RGIPG 1444 Query: 1049 PPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPG 1108 P G G G PGP G G +GPPG PG L+ ++ KGEKG G G G GE G Sbjct: 1445 PVGEQGLPGSPGPDGPPGPMGPPGLPG------LKGDSGPKGEKGHPGLIGLIGPPGEQG 1498 Query: 1109 GGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI-GYEGRQGPPGP- 1166 G G LPGP G GP+G GI GP G G PGPPG GPPG G +G GP GP Sbjct: 1499 EKGDRG--LPGPQGSSGPKGEQGITGPSGPI--GPPGPPGLPGPPGPKGAKGSSGPTGPK 1554 Query: 1167 -----PGPPGPPSFPGPHRQTISV 1185 PGPPGPP PG Q + + Sbjct: 1555 GEAGHPGPPGPPGPPGEVIQPLPI 1578 Score = 498 bits (1282), Expect = e-140 Identities = 416/1206 (34%), Positives = 499/1206 (41%), Gaps = 263/1206 (21%) Query: 200 RPWAPLTGPSV------PPPSSERISEEVGLLQLLG-DPPPQQVTQTDD----------P 242 RP APL P + PPPS R ++ LL++L P +T+T P Sbjct: 14 RPGAPLLPPLLLLLLWAPPPS--RAAQPADLLKVLDFHNLPDGITKTTGFCATRRSSKGP 71 Query: 243 DVGLAYVFGPDANSGQVARYHFP-SLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLL 301 DV AY DA + +P S F DFS+L ++ L +I + Sbjct: 72 DV--AYRVTKDAQLSAPTKQLYPASAFPEDFSILTTVKAKKGSQAFLVSIYNEQ------ 123 Query: 302 GVKLSGVQDGHQDISLLYTEPGAGQTHTAASFR-LPAFVGQWTHLALSVAGGFVALYVDC 360 G++ G++ G + L G FR + G+W +ALSV V L +DC Sbjct: 124 GIQQIGLELGRSPVFLYEDHTGKPGPEDYPLFRGINLSDGKWHRIALSVHKKNVTLILDC 183 Query: 361 EEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEE 420 ++ L RS + G+ V D + F+G I +L D + + +C + Sbjct: 184 KKKTTKFLDRSDH--PMIDINGIIVFGTRILDEEVFEGDIQQLLFVSDHRAAYDYC-EHY 240 Query: 421 GDDSDGASGDS--------------GSGLG-----------DARELLREETGA-----AL 450 D D A D+ G G G D +L +E T + A Sbjct: 241 SPDCDTAVPDTPQSQDPNPDEYYTEGDGEGETYYYEYPYYEDPEDLGKEPTPSKKPVEAA 300 Query: 451 KPRLPAPPPVTTPPL---------AGGSSTED-------------------------SRS 476 K P +T P G ED Sbjct: 301 KETTEVPEELTPTPTEAAPMPETSEGAGKEEDVGIGDYDYVPSEDYYTPSPYDDLTYGEG 360 Query: 477 EEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGE------------ 524 EE +Q T GA+ + S PG + L+G+ E Sbjct: 361 EENPDQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADD--LEGEFTEETIRNLDENYYD 418 Query: 525 -------------PGVPGP-----PGRAGPPGSPCLPGPPGLPCP----VSPLGPAGPA- 561 PG+P G GP G G P + P P GP GPA Sbjct: 419 PYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAG 478 Query: 562 LQTVPGPQGPP---------GPPGRDGTPGRDGEPGDPG-------EDGKPGD------- 598 L PG GP GPPGR G PG DG PG PG G GD Sbjct: 479 LPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPM 538 Query: 599 ----------------------TGPQGFPGTPGDVGPKGD---KGDPG-VGERGPPGPQG 632 GP G G PG VGP G KG+PG VG +GP G QG Sbjct: 539 VSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQG 598 Query: 633 PPGPPGPSFRHDKLTFIDMEG----------SGFGG--DLEALRGPRGFPGPPGPPGVPG 680 PPGP G R + G GF G L +G RG PGP GPPG PG Sbjct: 599 PPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPG 658 Query: 681 LPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGE 740 GE G G GP GLPG PG G G G PGPPGPPG G G+ G KG++G Sbjct: 659 DDGERGDDG-----EVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGP 713 Query: 741 AGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGP 800 G PG G +G PG G G G G PG GP G PG PG PG P G EG G Sbjct: 714 QGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGE 773 Query: 801 FWSTARSADGPQGPPGLP---GLKGDPGVPGLPGAKGEVGADGVPGFP---GLPGREGIA 854 + GPQGP G P G+KG G+ GL G KGE G DG PGF G+ G G Sbjct: 774 --KGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEI 831 Query: 855 GPQGPKGDRGSRGEK------GDPG-------KDGVGQPGLPGPPGPPGPVVYVSEQDGS 901 GP GP+G+ G G K GDPG K +G PGLPG PG GP GS Sbjct: 832 GPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGP-------KGS 884 Query: 902 V--LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPA 959 + PG G G G PG GP+G G G RG GP+G G+PG P G + G Sbjct: 885 IGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPG----PKGNSGG-- 938 Query: 960 QKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMP 1019 G G PG RGP GP G G+ G G PG PG+ G+ G G++GE G +G Sbjct: 939 -DGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGET-------GFQGKT 990 Query: 1020 GPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPF 1079 GPPGPPG GP G P ++ E PGPPG PG QG PG G +G G PGP G Sbjct: 991 GPPGPPGVVGPQG-PTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAG---- 1045 Query: 1080 DFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFG-SSLPGPPGPPGPRGYPGIPGPKGE 1138 + G+ G G G G+RG PG G G GPPGPPGP G PG GP G Sbjct: 1046 --------LPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGA 1097 Query: 1139 S-IRGQPGPPGPQGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPG 1196 + G PG PGPQGPPG G +G G GP GP G GP + +PGP GP GPPG Sbjct: 1098 AGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGP----VGLPGPAGPVGPPG 1153 Query: 1197 PPGTMG 1202 G G Sbjct: 1154 EDGDKG 1159 Score = 447 bits (1151), Expect = e-125 Identities = 284/636 (44%), Positives = 314/636 (49%), Gaps = 64/636 (10%) Query: 443 REETGAALKPRLPAPPPVTTP---------------PLAGGSSTEDSRSEEVEEQTTVAS 487 R ETG K P PP V P P G E ++ T Sbjct: 981 RGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGD 1040 Query: 488 LGAQTLPGSDSVSTWDGSVRTPG--GRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGP 545 G LPG D G G G V GLKG +G PG PGP G G G GP Sbjct: 1041 PGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGP 1100 Query: 546 PGLPCPVSPLGPAGPALQT-VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGF 604 G+P P GP GPA + PG +GP GP GRDG G G PG G G PG+ G +G Sbjct: 1101 IGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGE 1160 Query: 605 PGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS-GFGGDLEAL 663 G PG G KGDKG+ G GP GPQGP G PGPS + +G G GD Sbjct: 1161 IGEPGQKGSKGDKGEQG--PPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGD---- 1214 Query: 664 RGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP 723 GPRGFPGPPGP G+ GLPG PG G + DV G G PG PG GP G PG GP GPP Sbjct: 1215 EGPRGFPGPPGPVGLQGLPGPPGEKG-ETGDV-GQMGPPGPPGPRGPSGAPGADGPQGPP 1272 Query: 724 GREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPP 783 G G PG G+KG GEAG PG G G PGP G RGE G +G G AGPPGP GPPG Sbjct: 1273 GGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDD 1332 Query: 784 GPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPG 843 GP G G GP + G GPPG G G+PG G PG GE G G PG Sbjct: 1333 GPKGSPGPVGFPGDPGPPGEPGPA--GQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPG 1390 Query: 844 FPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSV 902 G PG G G QG KG +G G +G PGK G +G G PG PGP G + Sbjct: 1391 KRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDG-----------L 1439 Query: 903 LSVPGPEGRPGFAGFPGPAGPKGNLGS---KGERGSPGPKGEKGEPGSIFSPDGGALGPA 959 +PGP G G G PGP GP G +G G +G GPKGEKG PG I G +GP Sbjct: 1440 RGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLI-----GLIGP- 1493 Query: 960 QKGAKGEPGFRGPPGPYGRPGYKGE---------IGFPGRPGRPGMNGLKGEKGEPGDAS 1010 G +GE G RG PGP G G KGE IG PG PG PG G KG KG G Sbjct: 1494 -PGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPT- 1551 Query: 1011 LGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR 1046 G +G G PGPPGPPGPPG + + A +R Sbjct: 1552 ---GPKGEAGHPGPPGPPGPPGEVIQPLPIQASRTR 1584 Score = 52.4 bits (124), Expect = 3e-06 Identities = 57/209 (27%), Positives = 73/209 (34%), Gaps = 32/209 (15%) Query: 1025 PGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQL 1084 P P P ++ E P P + P P+ ++G G G +D++ Sbjct: 290 PTPSKKPVEAAKETTEVPEELTPTP-----TEAAPMPETSEG-AGKEEDVGIGDYDYVPS 343 Query: 1085 EAEMKGEKGDRGDAGQKGERGE----PGGGGFFGSSLPGP-----PGPPGPRGYPGIPGP 1135 E D G+ E + PG G +S P PP G + G Sbjct: 344 EDYYTPSPYDDLTYGEGEENPDQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGE 403 Query: 1136 -KGESIRG--------------QPGPPGPQGPPGIG--YEGRQGPPGPPGPPGPPSFPGP 1178 E+IR P GP P YEG GP G G G P+ P Sbjct: 404 FTEETIRNLDENYYDPYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEP 463 Query: 1179 HRQTISVPGPPGPPGPPGPPGTMGASSGV 1207 PGP GP G PGPPGTMG + V Sbjct: 464 GMLIEGPPGPEGPAGLPGPPGTMGPTGQV 492 Score = 31.2 bits (69), Expect = 8.0 Identities = 46/177 (25%), Positives = 55/177 (31%), Gaps = 20/177 (11%) Query: 65 TPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEENIAGVGAEILNVAKGIRSF 124 T G P G P P DG P P+ P+ G + G Sbjct: 915 TGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPG---- 970 Query: 125 VQLWNDTVPTESLARAET--LVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSPGAHT 182 D +P R ET P GP + GP E G RG P PG Sbjct: 971 ----KDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGP--MGERGHPGPPGPPG 1024 Query: 183 TEAGTLPAPTPSPPSLGRPW-APLTGPSVPP-----PSSERISEEVGLLQLLGDPPP 233 + LP + G P A L G PP P + VG L L G+ P Sbjct: 1025 EQG--LPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGP 1079 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 547 bits (1410), Expect = e-155 Identities = 354/832 (42%), Positives = 392/832 (47%), Gaps = 129/832 (15%) Query: 455 PAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVK 514 P P P G + E ++ E G +PG DG +PG Sbjct: 416 PGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGA 475 Query: 515 EG--GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG-PALQTVPGPQGP 571 G G G++G PG GP G G PG G G P P P G AG P VPG G Sbjct: 476 NGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGM 535 Query: 572 PGPPGRDGTPGRDGEPGDPGEDGK------PGDTGPQGFPGTPGDVGPKGDKGDPGV-GE 624 G PG G PG DG+PG PG G+ PG +GP+G PG G GPKG+ G PG GE Sbjct: 536 RGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGE 595 Query: 625 RGPPG---PQGPPG---------PPGPSFRHDKLTFIDMEGSGFGGDL-----EALRGPR 667 RG PG PQGPPG PPGP+ G GGD +G + Sbjct: 596 RGGPGGPGPQGPPGKNGETGPQGPPGPT--------------GPGGDKGDTGPPGPQGLQ 641 Query: 668 GFPGPPGPPGVPGLPGEPGRFG-VNSSDVPGPAGLPGVPGREGPPGFPGLPG-------- 718 G PG GPPG G PGEPG G + PG G G PG GPPG G PG Sbjct: 642 GLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPP 701 Query: 719 ----------PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAP 768 PPGPPG G PG G G G G+PG KG KG PG GA G G G Sbjct: 702 GPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPR 761 Query: 769 GPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTA-RSADGPQGP---PGLPGLKGDP 824 GP GP GPPGP G PG G + G GP S R GP GP PG PG G+P Sbjct: 762 GPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEP 821 Query: 825 GVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGV-GQPGLP 883 G G GA GE G G PG G PG G AGP GP+G +G RG G PG G G GLP Sbjct: 822 GGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLP 881 Query: 884 GPPG------PPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPG 937 GPPG PPGP + DG PGP G G G PG +GPKG+ G GE+GSPG Sbjct: 882 GPPGSNGNPGPPGPSGSPGK-DGP----PGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPG 936 Query: 938 PKGEKGEPG-----------SIFSPDG-----GALGP-------AQKGAKGEPGFRGPPG 974 +G G PG + P G G+ GP + GA G G RGPPG Sbjct: 937 AQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPG 996 Query: 975 PYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTP 1034 P G PG G G PGR G PG +GL G G PG G G PG PG PG PGPPG P Sbjct: 997 PQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKG-DRGENGSPGAPGAPGHPGPPG-P 1054 Query: 1035 VYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGD 1094 V + + GP G G PGP G++G GP GP G KGE G+ Sbjct: 1055 VGPAGKSGDRGESGPAG---PAGAPGPAGSRGAPGPQGPRGD------------KGETGE 1099 Query: 1095 RGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG 1154 RG AG KG RG PG G PG PGP G +G G PGP G GP GP GPPG Sbjct: 1100 RGAAGIKGHRGFPGNPG-----APGSPGPAGQQGAIGSPGPAGPR-----GPVGPSGPPG 1149 Query: 1155 IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSG 1206 +G G PGP GPPGP G R + PG PG PGPPGPPG G G Sbjct: 1150 --KDGTSGHPGPIGPPGPRGNRG-ERGSEGSPGHPGQPGPPGPPGAPGPCCG 1198 Score = 528 bits (1359), Expect = e-149 Identities = 350/882 (39%), Positives = 396/882 (44%), Gaps = 152/882 (17%) Query: 426 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 485 G SG +G R E G P + P + P G D R+ E E Sbjct: 222 GPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAP 281 Query: 486 ASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG-----------GLKGQKGEPGVPGPPGRA 534 G LPG + G PG R + G G +G G+PG PGPPG A Sbjct: 282 GLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTA 341 Query: 535 GPPGSPCL---------------------------------PGPPGL---PCPVSPLGPA 558 G PGSP PGPPG+ P +GPA Sbjct: 342 GFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPA 401 Query: 559 G-PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQG------FPGTPGDV 611 G P + G +GPPGP G +G PG G G+PG++G G+ GP+G PG PG Sbjct: 402 GIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAK 461 Query: 612 GPKGDKGDPG----------VGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLE 661 G G G PG GERG PG +GP GP G + Sbjct: 462 GEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNG---------------------IP 500 Query: 662 ALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPG 721 +GP G G PGP G G GEPGR GV PG G+PG PG G G PG PG G Sbjct: 501 GEKGPAGERGAPGPAGPRGAAGEPGRDGVPGG--PGMRGMPGSPGGPGSDGKPGPPGSQG 558 Query: 722 PPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPG 781 GR GPPG +G +G G G PG KG+ GAPG G RG G G GP G G GP G Sbjct: 559 ESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQG 618 Query: 782 PPGPGLPA------------GFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGL 829 PPGP P G + G+GGP G G PG PG KGD G PG Sbjct: 619 PPGPTGPGGDKGDTGPPGPQGLQGLPGTGGP--------PGENGKPGEPGPKGDAGAPGA 670 Query: 830 PGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGP 888 PG KG+ GA G G PGL G G+ G GP G G +G G PG G G PGL G PG Sbjct: 671 PGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGE 730 Query: 889 PGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSI 948 G + + PG G G G GP GP G +G G G PG KGE G PG Sbjct: 731 RGGLGSPGPKGDK--GEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGL- 787 Query: 949 FSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGD 1008 G GP +G+ GE G GPPGP G PG G+ G PG G G G KGE G PG Sbjct: 788 ----PGIAGP--RGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGV 841 Query: 1009 ASL--GFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKG 1066 A G G G PGP G G G PG P + PGPPG GN GPPGP G+ G Sbjct: 842 AGPPGGSGPAGPPGPQGVKGERGSPGGP-GAAGFPGARGLPGPPGSNGNPGPPGPSGSPG 900 Query: 1067 EVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGS----------- 1115 + GPPGP G G G +GDAGQ GE+G PG G G+ Sbjct: 901 KDGPPGPAGNTG------APGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITG 954 Query: 1116 --SLPGPPGPPGPRGYPGIPGPKGES-------IRGQPGPPGPQGPPGI----GYEGRQG 1162 L GPPG PGPRG PG G KGES + G+ GPPGPQG PG+ G GR G Sbjct: 955 ARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDG 1014 Query: 1163 PPGPPGPPGPPSFPG--PHRQTISVPGPPGPPGPPGPPGTMG 1202 PG G PG PG R PG PG PG PGPPG +G Sbjct: 1015 NPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVG 1056 Score = 527 bits (1358), Expect = e-149 Identities = 336/797 (42%), Positives = 376/797 (47%), Gaps = 133/797 (16%) Query: 507 RTPGGRVKEGGLKGQKGEPGVPG---PPGRAGPPGSPCLPGPPGL--PCPVSPL------ 555 R P G+ +G KG G PG+PG PG G PGSP PGPPG+ CP P Sbjct: 97 RPPNGQGPQGP-KGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQY 155 Query: 556 -------GPAGPALQTVPGPQGPP---GPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFP 605 G A L PGP GPP GPPG G PG G PG G G+PG GP G P Sbjct: 156 DSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPP 215 Query: 606 GTPGDVGPKGDKGDPG-VGERGPPGPQGPPGPPGPSFRHDKLTFIDMEG-SGFGG----- 658 G PG +GP G G G G G PG +G PGPPG F M+G GF G Sbjct: 216 GPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEK 275 Query: 659 ---------DLEALRGPRGFPGPPGPPGVP---GLPGEPGRFGVNSSD-VPGPAGLPGVP 705 L G G PGP GP G P G PG PG G +D G G PG P Sbjct: 276 GETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPP 335 Query: 706 GREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLA 765 G G GFPG PG G G G PG G G GE G GH G++G PGP G G G Sbjct: 336 GPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGK 395 Query: 766 GAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPG 825 G GPAG PG PG G GP PAG + G G + +G +G PG G +G+ G Sbjct: 396 GEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGK--NGAKGEPGPRGERGEAG 453 Query: 826 VPGLPGAKGEVGADGVPGFP------------------------GLPGREGIAGPQGPKG 861 +PG+PGAKGE G DG PG P G+PG +G AG +G G Sbjct: 454 IPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPG 513 Query: 862 DRGSRGEKGDPGKDGV----GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGF 917 G RG G+PG+DGV G G+PG PG PG DG PGP G G +G Sbjct: 514 PAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPG-------SDGK----PGPPGSQGESGR 562 Query: 918 PGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYG 977 PGP GP G G G G PGPKG G PG GG GP +G G+ G GP GP G Sbjct: 563 PGPPGPSGPRGQPGVMGFPGPKGNDGAPGK-NGERGGPGGPGPQGPPGKNGETGPQGPPG 621 Query: 978 RPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYD 1037 G G+ G G PG G+ GL G G PG+ G PG PGP G G PG P Sbjct: 622 PTGPGGDKGDTGPPGPQGLQGLPGTGGPPGE-------NGKPGEPGPKGDAGAPGAPGGK 674 Query: 1038 SNVFAESSR-----PGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEK 1092 + A R G PGL G GPPGP+G KG GPPGPPG LQ M GE+ Sbjct: 675 GDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQ---GMPGER 731 Query: 1093 GDRGDAGQKGERGEPGGGGFFG-------SSLPGPPGPPGPR------------GYPGIP 1133 G G G KG++GEPGG G G GP GPPGP G PGI Sbjct: 732 GGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIA 791 Query: 1134 GPKGE-SIRGQPGPPGPQGPPGI-------GYEGRQGPPGPPGPPGPPSFPGPHRQTISV 1185 GP+G RG+ GPPGP G PG G +G +G PG G GPP GP Sbjct: 792 GPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGP------- 844 Query: 1186 PGPPGPPGPPGPPGTMG 1202 PG GP GPPGP G G Sbjct: 845 PGGSGPAGPPGPQGVKG 861 Score = 469 bits (1206), Expect = e-131 Identities = 312/728 (42%), Positives = 335/728 (46%), Gaps = 137/728 (18%) Query: 550 CPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPG 609 CP P P P GPQGP G PG G PGR+G+PG PG+ PG+PG Sbjct: 88 CPQPPTAPTRPP--NGQGPQGPKGDPGPPGIPGRNGDPGIPGQ------------PGSPG 133 Query: 610 DVGPKG----------------DKGD--PGV---GERGPPGPQGPPGPPGPSFRHDKLTF 648 GP G D D GV G G PGP GPPGPPGP Sbjct: 134 SPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPP-------- 185 Query: 649 IDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP-------GPAGL 701 G G PG PG PG G PGEPG+ G + P GPAG Sbjct: 186 ----------------GTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGK 229 Query: 702 PGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGE 761 G GR G PG GLPGPPG G G PG G KG G G G KG GAPG G G Sbjct: 230 DGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGL 289 Query: 762 SGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLK 821 G GAPGP GP G PG G PG AG +G AR +DG GPPG P Sbjct: 290 PGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDG--------ARGSDGQPGPPGPP--- 338 Query: 822 GDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQ---------GPKGDRGSRGEKGDP 872 G G PG PGAKGEVG G PG G PG+ G GPQ GP G GS G KG+ Sbjct: 339 GTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEM 398 Query: 873 GKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKG 931 G G+ G PGL G GPPGP + G G PG G G GP+G G G Sbjct: 399 GPAGIPGAPGLMGARGPPGPA-----GANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAG 453 Query: 932 ERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRP 991 G PG KGE G+ GS P L P G +G PGFRGP GP G PG KG G G P Sbjct: 454 IPGVPGAKGEDGKDGSPGEPGANGL-PGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAP 512 Query: 992 GRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPP- 1050 G G G GE G G G GMRGMPG PG PG G PG P ES RPGPP Sbjct: 513 GPAGPRGAAGEPGRDGVPG-GPGMRGMPGSPGGPGSDGKPGPP----GSQGESGRPGPPG 567 Query: 1051 -----GLPGNQGPPGPK------GAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAG 1099 G PG G PGPK G GE G PG PG E +G G G G Sbjct: 568 PSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGG 627 Query: 1100 QKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGES-------IRGQPGPPGPQGP 1152 KG+ G PG G G LPG GPPG G PG PGPKG++ +G G PG +GP Sbjct: 628 DKGDTGPPGPQGLQG--LPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGP 685 Query: 1153 PGI----GYEGRQGPPGP------PGPPGPPSFPGP--------HRQTISVPGPPGPPGP 1194 PG+ G G GPPGP GPPGPP G R + PGP G G Sbjct: 686 PGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGE 745 Query: 1195 PGPPGTMG 1202 PG PG G Sbjct: 746 PGGPGADG 753 Score = 238 bits (606), Expect = 4e-62 Identities = 154/369 (41%), Positives = 171/369 (46%), Gaps = 68/369 (18%) Query: 855 GPQGPKGDRGSRGEKGDPGKDGV-GQPGLPGPPGPPG--------PVVYVSEQDGSVLSV 905 GPQGPKGD G G G G G+ GQPG PG PGPPG P Y + D V Sbjct: 103 GPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDS--YDV 160 Query: 906 PGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKG 965 G AG+PGPAGP G PGP G G PGS G Sbjct: 161 KSGVAVGGLAGYPGPAGPPG---------PPGPPGTSGHPGS----------------PG 195 Query: 966 EPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPP 1025 PG++GPPG G+ G G G PG G G G GE G PG G RG+PGPPG Sbjct: 196 SPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRP----GERGLPGPPGIK 251 Query: 1026 GPPGPPGTPVYDSNVF-----AESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFD 1080 GP G PG P + E G PGL G G PG GA G +GP G PG+ Sbjct: 252 GPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGE---- 307 Query: 1081 FLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE-- 1138 +G G G AG +G G G G PGPPGPPG G+PG PG KGE Sbjct: 308 --------RGRPGLPGAAGARGNDGARGSDG-----QPGPPGPPGTAGFPGSPGAKGEVG 354 Query: 1139 --SIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPP 1195 G G PG +G PG G+ G QGPPGPPG G P G +PG PG G Sbjct: 355 PAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKG-EMGPAGIPGAPGLMGAR 413 Query: 1196 GPPGTMGAS 1204 GPPG GA+ Sbjct: 414 GPPGPAGAN 422 Score = 209 bits (531), Expect = 2e-53 Identities = 147/362 (40%), Positives = 161/362 (44%), Gaps = 73/362 (20%) Query: 856 PQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFA 915 P P +G +G KGDPG PG+PG G PG G+PG Sbjct: 95 PTRPPNGQGPQGPKGDPGP-----PGIPGRNGD-----------------PGIPGQPGSP 132 Query: 916 GFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGP 975 G PGP G E GP+ + S G A+G G G PG GPPGP Sbjct: 133 GSPGPPGIC-------ESCPTGPQNYSPQYDSYDVKSGVAVG----GLAGYPGPAGPPGP 181 Query: 976 YGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPV 1035 G PG G PG PG G +G GEPG A G G PGPPG GP GP G Sbjct: 182 PGPPGTSGH------PGSPGSPGYQGPPGEPGQA----GPSGPPGPPGAIGPSGPAGKD- 230 Query: 1036 YDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDR 1095 ES RPG PG G GPPG KG G G PG G FD GEKG+ Sbjct: 231 ------GESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFD------GRNGEKGET 278 Query: 1096 GDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKG----ESIRGQPGPPGPQG 1151 G G KGE G PG G G GP G PG RG PG+PG G + RG G PGP G Sbjct: 279 GAPGLKGENGLPGENGAPGPM--GPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPG 336 Query: 1152 PPGI----GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPG---PPGPPGPPGTMGAS 1204 PPG G G +G GP G PG PG + PGP G GPPGPPG G+ Sbjct: 337 PPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGE----PGPQGHAGAQGPPGPPGINGSP 392 Query: 1205 SG 1206 G Sbjct: 393 GG 394 Score = 187 bits (476), Expect = 5e-47 Identities = 125/310 (40%), Positives = 142/310 (45%), Gaps = 61/310 (19%) Query: 932 ERGSPGPKGEKGE-----PGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIG 986 E P P+ GE P +P G +G KG+PG G PG G PG G+ G Sbjct: 71 ELDCPNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPG 130 Query: 987 FPGRPGRPGM-----NGLKG--EKGEPGDASLGF---GMRGMPGPPGPPGPPGPPGTPVY 1036 PG PG PG+ G + + + D G G+ G PGP GPPGPPGPPGT Sbjct: 131 SPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGT--- 187 Query: 1037 DSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRG 1096 S PG PG PG QGPPG G G GPPGPPG G G Sbjct: 188 -------SGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAI---------------GPSG 225 Query: 1097 DAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE-------SIRGQPGPPGP 1149 AG+ GE G PG G G LPGPPG GP G PG PG KG +G+ G PG Sbjct: 226 PAGKDGESGRPGRPGERG--LPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGL 283 Query: 1150 QGPPGI----GYEGRQGPPGPPGPPGPPSFPGPH--------RQTISVPGPPGPPGPPGP 1197 +G G+ G G GP G PG G P PG R + PGPPGPPG G Sbjct: 284 KGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGF 343 Query: 1198 PGTMGASSGV 1207 PG+ GA V Sbjct: 344 PGSPGAKGEV 353 Score = 39.3 bits (90), Expect = 0.029 Identities = 55/216 (25%), Positives = 74/216 (34%), Gaps = 31/216 (14%) Query: 46 PEPQGPL-PVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPE 104 P P GP+ P + D G + PA G+P P G P + + E Sbjct: 1049 PGPPGPVGPAGKSGD--------RGESGPAGPAGAPGPAGSRGAPGPQGPRG-DKGETGE 1099 Query: 105 ENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQEN 164 AG+ KG R F + + P GP GPS P ++ Sbjct: 1100 RGAAGI--------KGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKD 1151 Query: 165 GTTLWPSRGIPSSPGAHTTEAGTLPAP----TPSPPSLGRPWAPLTGPSVPPPSSERIS- 219 GT+ P P P + E G+ +P P PP G P AP GP + I+ Sbjct: 1152 GTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPP--GPPGAP--GPCCGGVGAAAIAG 1207 Query: 220 ----EEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFG 251 + G GD P TD+ L V G Sbjct: 1208 IGGEKAGGFAPYYGDEPMDFKINTDEIMTSLKSVNG 1243 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 545 bits (1405), Expect = e-154 Identities = 366/891 (41%), Positives = 413/891 (46%), Gaps = 163/891 (18%) Query: 418 DEEGDDSDGASGDSG--SGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSR 475 D+E +G GD+G G A R+ G +P LP PP PP G Sbjct: 104 DQETTGVEGPKGDTGPRGPRGPAGPPGRD--GIPGQPGLPGPPGPPGPPGPPGLG----- 156 Query: 476 SEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAG 535 + Q G D ST SV P G G +G G PG PGP G G Sbjct: 157 ----------GNFAPQLSYGYDEKSTGGISVPGPMG---PSGPRGLPGPPGAPGPQGFQG 203 Query: 536 PPGSPCLPGPPGLPCPVSPLGPAGPALQTV----------PGPQGPPGPPGRDGTPGR-- 583 PPG P G PG P+ P GP GP + PG +GPPGP G G PG Sbjct: 204 PPGEP---GEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAG 260 Query: 584 -------------------------DGEPGDPGEDGKPGDTGPQGFPGT---PGDVGPKG 615 GEPG PGE+G PG GP+G PG PG GP G Sbjct: 261 LPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAG 320 Query: 616 DKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPG 674 +G+ G G GPPGP GP GPPG F + G G E +G RG PGPPG Sbjct: 321 ARGNDGATGAAGPPGPTGPAGPPG--FPGAVGAKGEAGPQGPRGS-EGPQGVRGEPGPPG 377 Query: 675 PPGV------PGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGP 728 P G PG G+PG G N + PG AG PG PG GP G G GPPGP G G Sbjct: 378 PAGAAGPAGNPGADGQPGAKGANGA--PGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGE 435 Query: 729 PGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLP 788 PG G KG G G PG G +G PGPAG G+ G G PGP G PGPPG G PG Sbjct: 436 PGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGF 495 Query: 789 AGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVP------ 842 G D + G GP + R + GP GP G PG G PG GLPGAKG G+ G P Sbjct: 496 PGADGVAGPKGP--AGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKT 553 Query: 843 GFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-------VGQPGLPGPP--------- 886 G PG G++G GP GP G RG G G PG G G+ G+PGPP Sbjct: 554 GPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKD 613 Query: 887 ------GPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGER------G 934 GPPGP E+ GP G PGF G PGPAGP G G GE+ G Sbjct: 614 GEAGAQGPPGPAGPAGER-----GEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLG 668 Query: 935 SPGPKGEKGEPG-----SIFSPDG-----GALG-PAQKGAKGEPGFRGPPGPYGRPGYKG 983 +PGP G +GE G + P G GA G P GAKG+ G G PG G PG +G Sbjct: 669 APGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQG 728 Query: 984 EIGFPGRPGRPGMNGLKGEKGEPG-DASLG-FGMRGMPGPPGPPGPPGPPGTPVYDSNVF 1041 G G G PG G +G+ G G D S G G+RG+ GP GPPGP G PG +S Sbjct: 729 MPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDK-GESGPS 787 Query: 1042 AESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQK 1101 + G G PG++G PGP G G GPPG GQ G KG+ GDAG K Sbjct: 788 GPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQ------------PGAKGEPGDAGAK 835 Query: 1102 GERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI------ 1155 G+ G PG GP GPPGP G G PG KG RG GPPG G PG Sbjct: 836 GDAGPPGPA--------GPAGPPGPIGNVGAPGAKG--ARGSAGPPGATGFPGAAGRVGP 885 Query: 1156 -GYEGRQGPPGPPGPPGPPSFPGPHRQT--ISVPGPPGPPGPPGPPGTMGA 1203 G G GPPGPPGP G GP +T PG GPPGPPGP G G+ Sbjct: 886 PGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGS 936 Score = 538 bits (1387), Expect = e-152 Identities = 433/1185 (36%), Positives = 494/1185 (41%), Gaps = 211/1185 (17%) Query: 134 TESLARAETLVLETP---VGPLALAGPSSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPA 190 +ES ET +E P GP GP+ P +G P G+P PG P Sbjct: 99 SESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQP--GLPGPPG---------PP 147 Query: 191 PTPSPPSLGRPWAPLT----------GPSVPPPSSERISEEVGLLQLLGDPPPQ--QVTQ 238 P PP LG +AP G SVP P S GL G P PQ Q Sbjct: 148 GPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGP--SGPRGLPGPPGAPGPQGFQGPP 205 Query: 239 TDDPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAM 298 + + G + GP G P D RP GP Sbjct: 206 GEPGEPGASGPMGPRGPPGP------PGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTA 259 Query: 299 VLLGVKLSGVQDGHQDISLLYTEPG----AGQTHTAASFRLPAFVGQWTHLALSVAGGFV 354 L G+K GH+ S L G AG S GQ L G Sbjct: 260 GLPGMK------GHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRP 313 Query: 355 ALYVDCEEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQ---- 410 P +RG + GA G A P F G + K PQ Sbjct: 314 GA----------PGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGA-KGEAGPQGPRG 362 Query: 411 -VSPMHCLDEEGDDSD-GASGDSGSGLGDARELLREETGA---ALKPRLPAPPPVTTPPL 465 P E G GA+G +G+ D + + GA A P P + P Sbjct: 363 SEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQG 422 Query: 466 AGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEP 525 GG S E + GA+ PG V G P G + G +G+ G Sbjct: 423 PGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPG----PAGEEGKRGARGEPGPT 478 Query: 526 GVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGR-- 583 G+PGPPG G PGS PG G+ P P G G PGP GP G PG G PG Sbjct: 479 GLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGS-----PGPAGPKGSPGEAGRPGEAG 533 Query: 584 -------DGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-------------- 622 G PG PG DGK G GP G G PG GP G +G GV Sbjct: 534 LPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPG 593 Query: 623 --GERGPPGP---------------QGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRG 665 GERG PGP QGPPGP GP+ + G G G Sbjct: 594 KAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGE--------QGPAGS----PG 641 Query: 666 PRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPG---LPGPPGP 722 +G PGP GPPG G PGE G VPG G PG G G GFPG + GPPGP Sbjct: 642 FQGLPGPAGPPGEAGKPGEQG--------VPGDLGAPGPSGARGERGFPGERGVQGPPGP 693 Query: 723 PGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGP 782 G G G G G+ G+AGAPG GS+GAPG G GE G AG PGP G G GP G Sbjct: 694 AGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGA 753 Query: 783 PGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVP 842 G G D + G GP GP GP G PG KG+ G G G G GA G Sbjct: 754 DGS---PGKDGVRGLTGPI--------GPPGPAGAPGDKGESGPSGPAGPTGARGAPGDR 802 Query: 843 GFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGS 901 G PG PG G AGP G G G++GE GD G G G PG GP GPPGP+ V Sbjct: 803 GEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAK 862 Query: 902 ----VLSVPGPEGRPGFAGFPGPAGPKGNLGSKG------ERGSPGPKGEKG---EPGSI 948 PG G PG AG GP GP GN G G + G GP+GE G PG + Sbjct: 863 GARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEV 922 Query: 949 FSPDGGALGPAQKGAKGEPGFRGP------PGPYGRPGYKGEIGFPGRPGRPGMNGLKGE 1002 P G GPA G KG PG GP PGP G G +G +G PG+ G G GL G Sbjct: 923 GPP--GPPGPA--GEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGP 978 Query: 1003 KGEPGDA--SLGFGMRGMPGPPGPPGPPGPPG------------TPVYDSNVFAESSR-- 1046 GEPG S G RG PGP GPPG GPPG +P D + A+ R Sbjct: 979 SGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGE 1038 Query: 1047 ---------PGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGD 1097 PG PG PG GP G G +GE GP GP G + A +G +GD+G+ Sbjct: 1039 TGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGE 1098 Query: 1098 AGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI-- 1155 G++G+RG G GF G L GPPGPPG PG GP G S GP GP+GPPG Sbjct: 1099 TGEQGDRGIKGHRGFSG--LQGPPGPPGS---PGEQGPSGAS-----GPAGPRGPPGSAG 1148 Query: 1156 --GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPP 1198 G +G G PGP GPPGP G + PGPPGPPGPPGPP Sbjct: 1149 APGKDGLNGLPGPIGPPGPRGRTGD-AGPVGPPGPPGPPGPPGPP 1192 Score = 528 bits (1361), Expect = e-149 Identities = 352/818 (43%), Positives = 394/818 (48%), Gaps = 170/818 (20%) Query: 517 GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP-------ALQ------ 563 G++G KG+ G GP G AGPPG +PG PGLP P P GP GP A Q Sbjct: 109 GVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYD 168 Query: 564 -------TVPGPQGP------PGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGD 610 +VPGP GP PGPPG G G G PG+PGE G G GP+G PG PG Sbjct: 169 EKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGK 228 Query: 611 VGPKGDKGDPG-VGERGPPGPQGPPGPPG----PSFR-HDKLTFIDMEGSGFGGDLEALR 664 G G+ G PG GERGPPGPQG G PG P + H + +D G GD Sbjct: 229 NGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLD----GAKGDAGPA- 283 Query: 665 GPRGFPGPPGPPGVPG------LPGEPGRFGV-------NSSDVPGPAGLPGVPGREGPP 711 GP+G PG PG G PG LPGE GR G + G AG PG G GPP Sbjct: 284 GPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPP 343 Query: 712 GFPGL------PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA---PGPAGARGES 762 GFPG GP GP G EGP G G+ G G AGA G G+ GA PG GA G Sbjct: 344 GFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAP 403 Query: 763 GLAGAPG------PAGPPGPPGPPGPPG----PGLPAGFDDMEGSGGPFWSTARSADGPQ 812 G+AGAPG P+GP GP GPPGP G PG P D G P + GP Sbjct: 404 GIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPA 463 Query: 813 GPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGS---RGEK 869 G G G +G+PG GLPG GE G PG G PG +G+AGP+GP G+RGS G K Sbjct: 464 GEEGKRGARGEPGPTGLPGPPGERGG---PGSRGFPGADGVAGPKGPAGERGSPGPAGPK 520 Query: 870 GDPGKDG-------------VGQPGLPGPPG---PPGPVVYVSEQDG--SVLSVPGPEGR 911 G PG+ G G PG PGP G PPGP + QDG PG G+ Sbjct: 521 GSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGP----AGQDGRPGPPGPPGARGQ 576 Query: 912 PGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGP----------AQK 961 G GFPGP G G G GERG PGP G G G + GA GP ++ Sbjct: 577 AGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGK--DGEAGAQGPPGPAGPAGERGEQ 634 Query: 962 GAKGEPGFRGPPGPYGRPGYKG---EIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGM 1018 G G PGF+G PGP G PG G E G PG G PG +G +GE+G PG+ RG+ Sbjct: 635 GPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGE-------RGV 687 Query: 1019 PGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFP 1078 GPPGP GP G G P D G PG PG+QG PG +G GE G G PG Sbjct: 688 QGPPGPAGPRGANGAPGNDG----AKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGP-- 741 Query: 1079 FDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE 1138 KGDRGDAG KG G PG G G L GP GPPGP G PG G G Sbjct: 742 -------------KGDRGDAGPKGADGSPGKDGVRG--LTGPIGPPGPAGAPGDKGESGP 786 Query: 1139 S-------------IRGQPGPPGPQG---PPGI----------GYEGRQGPPGPPGPPGP 1172 S RG+PGPPGP G PPG G G +G GPPGP GP Sbjct: 787 SGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGP 846 Query: 1173 PSFPGPHRQTISVPGPPGP---PGPPGPPGTMGASSGV 1207 PGP + PG G GPPG G GA+ V Sbjct: 847 AGPPGPIGN-VGAPGAKGARGSAGPPGATGFPGAAGRV 883 Score = 527 bits (1357), Expect = e-149 Identities = 347/839 (41%), Positives = 386/839 (46%), Gaps = 111/839 (13%) Query: 425 DGASGDSGSGLGDARELLREETGAA--LKPR-LPAPPPVTTPPLAGGSSTEDSRSEEVEE 481 DGA GD+G E GA + PR LP P G+ D + Sbjct: 274 DGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGP 333 Query: 482 QTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPC 541 G PG+ G G R EG +G +GEPG PGP G AGP G+P Sbjct: 334 PGPTGPAGPPGFPGAVGAK---GEAGPQGPRGSEGP-QGVRGEPGPPGPAGAAGPAGNPG 389 Query: 542 LPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGP 601 G PG G AG PG +GP GP G G PG G G+PG G GDTG Sbjct: 390 ADGQPGAKGANGAPGIAGAP--GFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGA 447 Query: 602 QGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDL 660 +G PG G GP G G+ G G RG PGP G PGPPG F +G + Sbjct: 448 KGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADG------V 501 Query: 661 EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP 720 +GP G G PGP G G PGE GR G + +PG GL G PG GP G G PGP Sbjct: 502 AGPKGPAGERGSPGPAGPKGSPGEAGRPG--EAGLPGAKGLTGSPGSPGPDGKTGPPGPA 559 Query: 721 GPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPP 780 G GR GPPG G +G G G PG KG+ G PG AG RG G GA GPAG G G Sbjct: 560 GQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQ 619 Query: 781 GPPGPGLPAGFDDMEGSGGPFWSTA-RSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGAD 839 GPPGP PAG G GP S + GP GPPG G G+ GVPG GA G GA Sbjct: 620 GPPGPAGPAG---ERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGAR 676 Query: 840 GVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQ 898 G GFPG G+ GP GP G RG+ G G+ G G G PG PG G PG Sbjct: 677 GERGFPG---ERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPG-------- 725 Query: 899 DGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGP 958 + G G G AG PGP G +G+ G KG GSPG G +G G I P G A P Sbjct: 726 ------LQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPI-GPPGPAGAP 778 Query: 959 AQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPG---RPGMNGLKGEKGEPGDASLGFGM 1015 KG G G GP G G PG +GE G PG G PG +G G KGEPGDA G Sbjct: 779 GDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDA----GA 834 Query: 1016 RGMPGPPGPPGPPGPPGT-----------------PVYDSNVFAESSRPGPPGLPGNQGP 1058 +G GPPGP GP GPPG P + + R GPPG GN GP Sbjct: 835 KGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGP 894 Query: 1059 PGPKGAKG------------------EVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQ 1100 PGP G G EVGPPGPPG GEKG G G Sbjct: 895 PGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGP------------AGEKGSPGADGP 942 Query: 1101 KGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIPGPKGE-------SIRGQPGPPGPQGP 1152 G G PG G G + G PG G RG+PG+PGP GE G+ GPPGP GP Sbjct: 943 AGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGP 1002 Query: 1153 PGI----GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGV 1207 PG+ G GR+G PG G PG PG G GP GPPG PG GA V Sbjct: 1003 PGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDR----GETGPAGPPGAPGAPGAPGPV 1057 Score = 495 bits (1274), Expect = e-139 Identities = 335/844 (39%), Positives = 374/844 (44%), Gaps = 187/844 (22%) Query: 531 PGRAGPPGSPCLPGPPGLPCPVSP--LGPAGPALQTVP-GPQGPPGPPGRDGTPGRDGEP 587 PG P G C P G P G GP T P GP+GP GPPGRDG PG+ G P Sbjct: 82 PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLP 141 Query: 588 GDPGEDGKPGDTGPQGFPGTP---GDVGPK-----GDKGDPGVGERGPPGPQGPPGPPGP 639 G PG P G PG P G+ P+ +K G+ GP GP GP G PGP Sbjct: 142 GPPG---------PPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGP 192 Query: 640 SFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFG-------VNS 692 F G GPRG PGPPG G G G+PGR G + Sbjct: 193 PGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGA 252 Query: 693 SDVPGPAGLPGVPGREGPPGFPGL---PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGS 749 +PG AGLPG+ G G G G GP GP G G PG G G +G G PG +G Sbjct: 253 RGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGR 312 Query: 750 KGAPGPAGARGE---SGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTAR 806 GAPGPAGARG +G AG PGP GP GPPG PG G AG GS GP R Sbjct: 313 PGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGP--QGVR 370 Query: 807 SADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSR 866 GP GP G G G+PG G PGAKG GA G+ G PG PG G +GPQGP G G + Sbjct: 371 GEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPK 430 Query: 867 GEKGDPGKDG-------VGQPGLPGPPGPPGPVVYVSEQ----DGSVLSVPGPEGR---P 912 G G+PG G G+PG G GPPGP ++ + +PGP G P Sbjct: 431 GNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGP 490 Query: 913 GFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGP 972 G GFPG G G G GERGSPGP G KG PG P L P KG G PG GP Sbjct: 491 GSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGL-PGAKGLTGSPGSPGP 549 Query: 973 PGPYGRPGYKGEIGFPGRPGRPGMNGL---------KGEKGEPGDASLGFGMRGMPGPP- 1022 G G PG G+ G PG PG PG G KG GEPG A G RG+PGPP Sbjct: 550 DGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA----GERGVPGPPG 605 Query: 1023 --------------GPPGP---------PGPPGTPVYD-----SNVFAESSRPGPPGLPG 1054 GPPGP GP G+P + + E+ +PG G+PG Sbjct: 606 AVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPG 665 Query: 1055 NQGPPGPKGAKGE---------VGPPGP------------------------------PG 1075 + G PGP GA+GE GPPGP PG Sbjct: 666 DLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPG 725 Query: 1076 QFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGP 1135 + A + G KGDRGDAG KG G PG G G L GP GPPGP G PG G Sbjct: 726 LQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRG--LTGPIGPPGPAGAPGDKGE 783 Query: 1136 KGES-------------IRGQPGPPGP---QGPPG-------------IGYEGRQGPPGP 1166 G S RG+PGPPGP GPPG G +G GPPGP Sbjct: 784 SGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGP 843 Query: 1167 PGPPGPP------------------------SFPGPHRQTISVPGPPGPPGPPGPPGTMG 1202 GP GPP FPG + + PGP G GPPGPPG G Sbjct: 844 AGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGR-VGPPGPSGNAGPPGPPGPAG 902 Query: 1203 ASSG 1206 G Sbjct: 903 KEGG 906 Score = 408 bits (1048), Expect = e-113 Identities = 271/667 (40%), Positives = 304/667 (45%), Gaps = 97/667 (14%) Query: 447 GAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSV 506 GAA +P V PP A G + +D + GAQ PG Sbjct: 587 GAAGEPGKAGERGVPGPPGAVGPAGKDGEA------------GAQGPPG----------- 623 Query: 507 RTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG------- 559 P G E G +G G PG G PG AGPPG PG G+P + GP+G Sbjct: 624 --PAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGF 681 Query: 560 PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGD------VGP 613 P + V GP GP GP G +G PG DG GD G G PG G G G PG+ GP Sbjct: 682 PGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGP 741 Query: 614 KGDKGDPG----------------VGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFG 657 KGD+GD G G GPPGP G PG G S G+ Sbjct: 742 KGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGD 801 Query: 658 GDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNS-SDVPGPAGLPGVPGREGPPGFPGL 716 GP GF GPPG G PG GEPG G + PGPAG G PG P G G Sbjct: 802 RGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPG---PIGNVGA 858 Query: 717 PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGP 776 PG G G GPPG TG G+ G G PG G+ G PGP G G+ G G G GP G Sbjct: 859 PGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGR 918 Query: 777 PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPG------LPGLKGDPGVPGLP 830 PG GPPGP PAG G+ GP + A GPQG G LPG +G+ G PGLP Sbjct: 919 PGEVGPPGPPGPAGEKGSPGADGP--AGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLP 976 Query: 831 GAKGEVG------ADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-------- 876 G GE G A G G PG G G+AGP G G G+ G +G PG+DG Sbjct: 977 GPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDR 1036 Query: 877 -----VGQPGLPGPPGPPGPVVYVSEQ-DGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSK 930 G PG PG PG PGPV + D GP G G G GPAGP+G G K Sbjct: 1037 GETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDK 1096 Query: 931 GERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGR 990 GE G G +G KG G FS G GP G G PG +GP G G G +G G G Sbjct: 1097 GETGEQGDRGIKGHRG--FS---GLQGPP--GPPGSPGEQGPSGASGPAGPRGPPGSAGA 1149 Query: 991 PGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPP 1050 PG+ G+NGL G G PG G G GP GPPGPPGPPG P S F S P PP Sbjct: 1150 PGKDGLNGLPGPIGPPGPR----GRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPP 1205 Query: 1051 GLPGNQG 1057 + G Sbjct: 1206 QEKAHDG 1212 Score = 242 bits (618), Expect = 2e-63 Identities = 163/426 (38%), Positives = 180/426 (42%), Gaps = 64/426 (15%) Query: 426 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 485 G G+SG R G +P P P PP A G + E + Sbjct: 779 GDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADG---QPGAKGEPGDAGAK 835 Query: 486 ASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGP 545 G G G+V PG + G G G G PG GR GPPG GP Sbjct: 836 GDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSA-GPPGATGFPGAAGRVGPPGPSGNAGP 894 Query: 546 PGLPCPVSPLGPAGPALQTVP-------GPQGPPGPPGRDGTPGRDGEPGDPGEDGK--- 595 PG P P G GP +T P GP GPPGP G G+PG DG G PG G Sbjct: 895 PGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGI 954 Query: 596 ---------PGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDK 645 PG G +GFPG PG G G +G G GERGPPGP GPPG GP + Sbjct: 955 AGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGR 1014 Query: 646 LTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGV-------NSSDVPGP 698 EGS +G RG GP GPPG PG PG PG G + GP Sbjct: 1015 EGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGP 1074 Query: 699 AGLPGVPGREGPPG------------------------FPGLPGPPGPPG---REGPPGR 731 AG G G GP G F GL GPPGPPG +GP G Sbjct: 1075 AGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGA 1134 Query: 732 TGQ---KGSLGEAGAPGHKGSKGAPGPAGA---RGESGLAGAPGPAGPPGPPGPPGPPGP 785 +G +G G AGAPG G G PGP G RG +G AG GP GPPGPPGPPGPP Sbjct: 1135 SGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSA 1194 Query: 786 GLPAGF 791 G F Sbjct: 1195 GFDFSF 1200 Score = 42.4 bits (98), Expect = 0.003 Identities = 51/176 (28%), Positives = 59/176 (33%), Gaps = 13/176 (7%) Query: 46 PEPQGPLPVQPTADTTTHVTP--RNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAP 103 P P GP + P R G P PG P P E G D P A P Sbjct: 895 PGPPGPAGKEGGKGPRGETGPAGRPGEVGP---PGPPGPAGEKGSPGADGPAGAPGTPGP 951 Query: 104 EENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQE 163 + G L +G R F L + + P GP+ G + P E Sbjct: 952 QGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGE 1011 Query: 164 NGTTLWP----SRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWAPLTGPSVPPPSS 215 +G P S G SPGA T PA P P G P AP GP P S Sbjct: 1012 SGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAP--GAPGAP--GPVGPAGKS 1063 Score = 38.9 bits (89), Expect = 0.038 Identities = 42/170 (24%), Positives = 54/170 (31%), Gaps = 22/170 (12%) Query: 69 GSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEENIAGVGA---------------- 112 G P APG+P P + G+ P P + VGA Sbjct: 1040 GPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGET 1099 Query: 113 --EILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGTTLWP 170 + KG R F L P S P GP G + P ++G P Sbjct: 1100 GEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLP 1159 Query: 171 SRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWAPLTG---PSVPPPSSER 217 P P T +AG + P P P G P P G +P P E+ Sbjct: 1160 GPIGPPGPRGRTGDAGPVGPPGPPGPP-GPPGPPSAGFDFSFLPQPPQEK 1208 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 543 bits (1398), Expect = e-154 Identities = 372/895 (41%), Positives = 424/895 (47%), Gaps = 185/895 (20%) Query: 495 GSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGP---PGSPCLPGPPGLP-C 550 G V+ G PG + G Q G+PG+PG PGR G PG P LPG PGLP Sbjct: 635 GIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGI 694 Query: 551 PVSPLGPAGPA--LQTVPGPQGP---PGPPGRDGTPGR---DGEPGDPGEDGK------- 595 P S P P L PGP+G PGPPG GTPGR +G PG PG G Sbjct: 695 PGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFA 754 Query: 596 -PGDTGPQGFPGTPGDVGPKGDKGDPG-------------------VGERGPPGPQGPPG 635 PG GP G PG G +GPKGD+G PG VG G PGP GPPG Sbjct: 755 LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPG 814 Query: 636 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 695 PG I ++G GP G PGP G PG+ G+PGE G G DV Sbjct: 815 LPG----------IGVQGP---------PGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV 855 Query: 696 PGP------AGLPGVPGREGPPGFPGLP------------------GPPGPPGREGPPGR 731 PGP G+PG PG GPPG PGLP GPPGPPG G PGR Sbjct: 856 PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915 Query: 732 TGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGP--------PGPPGPPGPP 783 +G G G+ G G G G G G++GE GL G PGP P G PG PG P Sbjct: 916 SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975 Query: 784 GPGLPAGFDDMEGS-GGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVP 842 G P G+ + G G P S GP GP G PGL G PG+ G PG KG +G G P Sbjct: 976 GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFP 1035 Query: 843 GFPGL---PGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPG-------PV 892 G G+ PG G+ G G G G +G+KGDPG +G PGLPGP G PG P Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPG 1095 Query: 893 VYVSEQDGSVLSVPGPEGR------PGFAGFPGPAGPK---------------GNLGSKG 931 + S D + +PG G PGF G PGP GPK G +G G Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155 Query: 932 ERGSPGPKGEKGEPGSIFSPDGGALGPA-QKGAKGEPGFRGPPGPYGRPGYKGEIGFPGR 990 G PGP GEKG+PG G GPA QKG G+PGF G PGP G PG G+ G G Sbjct: 1156 HPGQPGPPGEKGKPG-----QDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGL 1209 Query: 991 PGRPGMNGLKGEKGEPGDASLGF-GMRGMPGPPGPPGP--PGPPGTPVYDSNVFAESSRP 1047 PG PG GL G KGEPG GF G++G PGPPG PGP GP G P P Sbjct: 1210 PGIPGNPGLPGPKGEPG--FHGFPGVQGPPGPPGSPGPALEGPKGNP-------GPQGPP 1260 Query: 1048 GPPGLPGNQGPP------GPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQK 1101 G PGLPG +GPP G KG KG G PG PG Q ++G G G G K Sbjct: 1261 GRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMK 1320 Query: 1102 GERGEPGGGGFFG----SSLPGPPGPP------GPRGYPGIPGPKGES--IRGQPGPPGP 1149 G+ G PG GF G S +PG GP GP G PG+PGP G+S I+G GPPG Sbjct: 1321 GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGI 1380 Query: 1150 QGPPGI-GYEGRQGPPGPPGPPGPPSFPGPH--------------------RQTISVPGP 1188 G PG+ G G QGP G PGP GPP PG + T + GP Sbjct: 1381 PGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGP 1440 Query: 1189 PGP---PGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVR 1240 PGP GPPGPPGT + G + TR + + P+G L LYV+ Sbjct: 1441 PGPDGLQGPPGPPGTSSVAHGFLI--TRHSQTTDAPQCPQGTLQVYEGFSLLYVQ 1493 Score = 535 bits (1377), Expect = e-151 Identities = 365/926 (39%), Positives = 421/926 (45%), Gaps = 193/926 (20%) Query: 423 DSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQ 482 D G G+ G R G P LP P PP G +D + Sbjct: 39 DCSGIKGEKGE---------RGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPK 89 Query: 483 TTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSP 540 G PG+ + G PG + G G KG++G PG PG PG GPPG P Sbjct: 90 GIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPP 149 Query: 541 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGP---PGPPGRDGTPGRDGEPGDPGEDGKPG 597 +PG G P + + ++PGP+G PGPPG G PG G PG G G PG Sbjct: 150 GIPGMKGEPGSI--------IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPG 201 Query: 598 DTGPQGFPGTPGD--------VGPKGDKGDPGV--------------------------- 622 GP G PG PG GPKG+KG+ G+ Sbjct: 202 LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261 Query: 623 --GERGPPGP---QGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPG 677 G+RGPPGP +GPPGPPG + +K +G G G PG PG PG Sbjct: 262 LPGDRGPPGPPGIRGPPGPPGGE-KGEK----GEQGEPGKRGKPGKDGENGQPGIPGLPG 316 Query: 678 VPGLPGEPGRFG----VNSSDVPGP-------------------AGLPGVPGREGPPGFP 714 PG PGEPGR G + PGP GLPG+PG +G GFP Sbjct: 317 DPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFP 376 Query: 715 GLPGPPGPP--------GREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAG 766 G+ GPPG P G GPPG G++G G+ G PG G PG G G GL G Sbjct: 377 GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPG-ISIPGPPGLDGQPGAPGLPG 435 Query: 767 APGPAGP----------PGPPGPPGPPGPGLPAGFDDMEGSGGP--FWSTARSADGPQGP 814 PGPAGP PGPPGPPG PG G ++G G F GP G Sbjct: 436 PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495 Query: 815 PGLPGLKGDPGVPGLPGAKGE------VGADGVPGFPGLPGREGIAGPQGPKGD------ 862 PGLPGL G PG G PG KGE G G+PG PG PG G G +G GD Sbjct: 496 PGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG 555 Query: 863 -RGSRGEKGDPGKDGV----------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGR 911 +G +GE G PG G+ G PGLPGP G PG + + E+ GP G Sbjct: 556 MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGER--------GPPGN 607 Query: 912 PGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFR- 970 PG G PG GP G G G PGP GEKG G +P P G KG+PG Sbjct: 608 PGLPGLPGNIGPMGPPGF----GPPGPVGEKGIQGVAGNPG----QPGIPGPKGDPGQTI 659 Query: 971 ---GPPGPYGRPGYKGEIGF---PGRPGRPGMNGLKGEKGEPGDASLGF-------GMRG 1017 G PG G PG G++G PG PG+PG+ G+ G KGEPG +G G G Sbjct: 660 TQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPG 719 Query: 1018 MPGPPGPP---------GPPGPPGTPVYDSNV-FAESSRPGPPGLPGNQGPPGPKGAKGE 1067 +PGPPG P GPPGPPG P FA PGPPGLPG +G GPKG +G Sbjct: 720 IPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF 779 Query: 1068 VGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPR 1127 GPPGPPG+ D L G KGD G GQ G G PG G PGPPG PGP Sbjct: 780 PGPPGPPGRTGLDGL------PGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPI 833 Query: 1128 GYPGIPGPKGESIRGQPGPPG--PQGPPG-IGYEGRQGPPGPPGPPGPPSFPGP------ 1178 G PG+ G GE +G PGPPG GPPG G G G PGP GPPG P PG Sbjct: 834 GQPGLHGIPGE--KGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGF 891 Query: 1179 --HRQTISVPGPPGPPGPPGPPGTMG 1202 + + + GPPGPPGP G PG G Sbjct: 892 PGTKGEMGMMGPPGPPGPLGIPGRSG 917 Score = 528 bits (1360), Expect = e-149 Identities = 344/783 (43%), Positives = 387/783 (49%), Gaps = 131/783 (16%) Query: 508 TPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPG 567 +PG + G+KG+KGE G PG G G PG P GPPG G GP PG Sbjct: 33 SPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGP-----PG 87 Query: 568 PQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGP 627 P+G GPPG G PG G PG PG DG P GPQG PG G G +G G PG Sbjct: 88 PKGIRGPPGLPGFPGTPGLPGMPGHDGAP---GPQGIPGCNGTKGERGFPGSPGF----- 139 Query: 628 PGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGR 687 PG QGPPGPPG M+G + +L GP+G PG PGPPG+ GLPG G Sbjct: 140 PGLQGPPGPPG---------IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTG- 189 Query: 688 FGVNSSDVPGPAGLPGVPGREGPPGFPGLPGP--------------PGPPGREGPPGRTG 733 +PGP G PG PG GPPG PGLPGP G G +GPPG G Sbjct: 190 -------IPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPG 242 Query: 734 Q----------------KGSLGEAGAPGHKGSKGAPG-PAGARGESGLAGAPGPAGPPGP 776 Q +G G+ G PG G +G PG P G +GE G G PG G PG Sbjct: 243 QISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGK 302 Query: 777 PGPPGPPG-PGLPAGFDDMEGSGGPFWSTARSAD-GPQGPPGLP----------GLKGDP 824 G G PG PGLP G G G + D GP GPPGL G KG+ Sbjct: 303 DGENGQPGIPGLP-GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNI 361 Query: 825 GVPGLPGAKGEVGADGVPGFPGLPGREGIA--GPQGPKGDRGSRGEKGDPGKDGV----- 877 G+PGLPG KGE G G+ G PGLPG G A GP GP G G RG+KGD G G+ Sbjct: 362 GLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP 421 Query: 878 -------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSK 930 G PGLPGPPGP GP + S++ + PGP G PG G G G +G G K Sbjct: 422 PGLDGQPGAPGLPGPPGPAGPHIPPSDE----ICEPGPPGPPGSPGDKGLQGEQGVKGDK 477 Query: 931 GE-------RGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKG 983 G+ G GP G+ G PG + P G P QKG KG+ G GP G G PG G Sbjct: 478 GDTCFNCIGTGISGPPGQPGLPG-LPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPG 536 Query: 984 EIGFPGRPGR-------PGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTP-- 1034 GFPG G PGM G KGE G PG L G+ G PG G PG PGP G P Sbjct: 537 APGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP-GLPGTPGQDGLPGLPGPKGEPGG 595 Query: 1035 VYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGD 1094 + PG PGLPGN GP GP G GPPGP G+ + G G Sbjct: 596 ITFKGERGPPGNPGLPGLPGNIGPMGPPG----FGPPGPVGEKGIQGVAGNPGQPGIPGP 651 Query: 1095 RGDAG----QKGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIPGPKGE---SIRGQPGP 1146 +GD G Q G+ G PG G G LPG PG PG G PGIPG KGE G PGP Sbjct: 652 KGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP 711 Query: 1147 PGPQGPPGIGYEGRQGPPGPP------GPPGPPSFPGPHRQT-ISVPGPPGPPGPPGPPG 1199 PGP+G PGI G G PG P GPPGPP FPGP + ++PGPPGPPG PG G Sbjct: 712 PGPKGFPGI--PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG 769 Query: 1200 TMG 1202 +G Sbjct: 770 ALG 772 Score = 442 bits (1137), Expect = e-123 Identities = 277/640 (43%), Positives = 316/640 (49%), Gaps = 79/640 (12%) Query: 494 PGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPG--------- 544 PG + G PG V G G++G PG+PG PG GPPGSP LPG Sbjct: 836 PGLHGIPGEKGDPGPPGLDVP--GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPG 893 Query: 545 ---------PPGLPCPVSPLGPAG-PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDG 594 PPG P P+ G +G P L+ G QG PG PG G G GEPG PG G Sbjct: 894 TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG 953 Query: 595 --------KPGDTGPQGFPGTPGDVGPKGDKGDPG----VGERGPPGPQGPPGPPGPSFR 642 G+ G G PG PG GPKG +G PG G G PG GPPGP G Sbjct: 954 PMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGL 1013 Query: 643 HDKLTFIDMEG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPA-- 699 + I G G GD+ GP+G GPPGP GVPG PG PG G D P Sbjct: 1014 PGQPGLIGPPGLKGTIGDM-GFPGPQGVEGPPGPSGVPGQPGSPGLPG-QKGDKGDPGIS 1071 Query: 700 --GLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAG 757 GLPG+PG +G PG PG PG PG G G PG G G+ G G PG G G PGP G Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131 Query: 758 ARGESGLAGAPGPAGPPGP------PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGP 811 +G SG G PG G PGP PG PGPPG G D + G G + G Sbjct: 1132 PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGN 1191 Query: 812 QGPPGLPGL---KGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGE 868 GPPGLPGL KGD G+PG+PG G G G PGF G PG +G GP G G G Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP-ALEGP 1250 Query: 869 KGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNL 927 KG+PG G G+PGLPGP GPPG +G + G G+PG G PG G +G Sbjct: 1251 KGNPGPQGPPGRPGLPGPEGPPG-----LPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPP 1305 Query: 928 GSKGERGSPGPKGEKGEPGSIFSP-----DGGALGPAQKGAKGEPGFRGPPGPYGRPG-- 980 G +G G PG G KG+PG P G + P G +GEPG GPPGP G PG Sbjct: 1306 GLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPS 1365 Query: 981 -----YKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPV 1035 KG+ G PG PG+PG+ GL G +G +G+PGP GPPG PG G P Sbjct: 1366 GQSIIIKGDAGPPGIPGQPGLKGLPGPQGP----------QGLPGPTGPPGDPGRNGLPG 1415 Query: 1036 YDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPG 1075 +D PG PG PG +G GP G G GPPGPPG Sbjct: 1416 FD-GAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1454 Score = 399 bits (1026), Expect = e-111 Identities = 256/609 (42%), Positives = 291/609 (47%), Gaps = 112/609 (18%) Query: 445 ETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDG 504 E G+ +P LP PP P L G S+ E+ E G +PG + G Sbjct: 939 EKGSKGEPGLPGPPGPMDPNLLG------SKGEKGEP-------GLPGIPGVSGPKGYQG 985 Query: 505 SVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP-ALQ 563 PG + GL GQ G PG PGP G G PG P L GPPGL + +G GP ++ Sbjct: 986 LPGDPG----QPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVE 1041 Query: 564 TVPGPQGPPGPPGRDGTPGRDGEPGDPGED-----GKPGDTGPQGFPGTPGDVGPKGDKG 618 PGP G PG PG G PG+ G+ GDPG G PG G G PG PG+ G KG G Sbjct: 1042 GPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVG 1101 Query: 619 DPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPG 671 DPG+ G +G PG G PG PGP GP+G G Sbjct: 1102 DPGLPGLPGTPGAKGQPGLPGFPGTPGPP------------------------GPKGISG 1137 Query: 672 PPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP--GREGPP 729 PPG PG+PG PG G G PGP G G PG++G PG G G PG P G GPP Sbjct: 1138 PPGNPGLPGEPGPVG--GGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPP 1195 Query: 730 GRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPA 789 G G G G+ G PG G+ G PGP +GE G G PG GPPGPPG PGP Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGP---KGEPGFHGFPGVQGPPGPPGSPGP------- 1245 Query: 790 GFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPG 849 + +G+ GP GP G PGLPG +G PG+PG G KGE G G PG PGLPG Sbjct: 1246 ALEGPKGNPGP--------QGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPG 1297 Query: 850 REGIAGP---QGPKGDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSV 905 +G GP QG G G G KGDPG GV G PG+ GP G PG Sbjct: 1298 LKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSA------------- 1344 Query: 906 PGPEGRPGFAGFPGPAGPKGNLG-SKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAK 964 GPEG PG G PGP G G G S +G GP G G+PG KG Sbjct: 1345 -GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPG-------------LKGLP 1390 Query: 965 GEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGP 1024 G G +G PGP G PG G G PG G G G G G+PG G+ G PGP G Sbjct: 1391 GPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTR----GLDGPPGPDGL 1446 Query: 1025 PGPPGPPGT 1033 GPPGPPGT Sbjct: 1447 QGPPGPPGT 1455 Score = 398 bits (1022), Expect = e-110 Identities = 267/677 (39%), Positives = 316/677 (46%), Gaps = 147/677 (21%) Query: 605 PGTPGDV-GPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEAL 663 PG+ D G KG+KG ERG PG +G PG PG Sbjct: 34 PGSKCDCSGIKGEKG-----ERGFPGLEGHPGLPG------------------------F 64 Query: 664 RGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP 723 GP G PGP G G G+PG PG G+ GP GLPG PG PG PG+PG G P Sbjct: 65 PGPEGPPGPRGQKGDDGIPGPPGPKGIR-----GPPGLPGFPGT---PGLPGMPGHDGAP 116 Query: 724 GREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGA------PGPAGPPGPP 777 G +G PG G KG G G+PG G +G PGP G G G G+ PGP G PG P Sbjct: 117 GPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYP 176 Query: 778 GPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVG 837 GPPG G P G GP GPPG PGL G PG PGLPG KG +G Sbjct: 177 GPPGIQGLPGPTGIP-----------------GPIGPPGPPGLMGPPGPPGLPGPKGNMG 219 Query: 838 ADGVPGFPGLPGREGIAGPQGP----------------KGDRGSRGEKGDPGKDGVGQPG 881 + G G G +G+ GP GP KGD+G G++G PG PG Sbjct: 220 LN-FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP-----PG 273 Query: 882 LPGPPGPPGPVVYVSEQDGSV-----LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSP 936 + GPPGPPG + G G G+PG G PG G G G GE+G Sbjct: 274 IRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQK 333 Query: 937 GPKGEKGEPGSIFSPDG--------GALG----PAQKGAKGEPGFRGPPGPYGRPGYKGE 984 G G G PG + G G +G P +KG +G PG +GPPG G PG Sbjct: 334 GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG-AAV 392 Query: 985 IGFPGRPGRPGMNGLKGEKGEPGDASLGF-GMRGMPGPPGPPGPPGPPGTPVYDSNVFAE 1043 +G PG PG PG G KG++G PG + G G+ G PG PG PGPPGP G + S+ E Sbjct: 393 MGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICE 452 Query: 1044 SSRPGPPGLPGNQGPPGPKGAKGEVG-------------PPGPPGQFPFDFLQLEAEMKG 1090 PGPPG PG++G G +G KG+ G PPG PG G Sbjct: 453 PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512 Query: 1091 EKGDRGDAGQKGERG------EPGGGGFFGS--------SLPGPPGP------PGPRGYP 1130 +KG++G AG G +G PG GF GS + PG G PG G P Sbjct: 513 QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572 Query: 1131 GIPGPKGESIRGQPGPPGPQGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPP 1189 G+PG G+ G PG PGP+G PG I ++G +GPPG PG PG P GP GPP Sbjct: 573 GLPGTPGQD--GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPM-------GPP 623 Query: 1190 G--PPGPPGPPGTMGAS 1204 G PPGP G G G + Sbjct: 624 GFGPPGPVGEKGIQGVA 640 Score = 386 bits (992), Expect = e-107 Identities = 260/666 (39%), Positives = 299/666 (44%), Gaps = 151/666 (22%) Query: 680 GLPGEPGR-FGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSL 738 G P E +G + +G+ G G G PG G PG PG PG EGPPG GQKG Sbjct: 21 GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80 Query: 739 GEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSG 798 G G PG KG +G PG G G GL G PG G PGP G PG G GF G Sbjct: 81 GIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP 140 Query: 799 GPFWSTARSADGPQGPPGLPGLKGDPG---VPGLPGAKGEVGADGVPGFPGLPGREGIAG 855 G GP GPPG+PG+KG+PG + LPG KG G G PG GLPG GI G Sbjct: 141 G--------LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPG 192 Query: 856 PQGPKGDRGSRGEKGDPGKDG---------------VGQPGLPGPPGPPGPV-------- 892 P GP G G G G PG G G+ GL GPPGPPG + Sbjct: 193 PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252 Query: 893 VYVSEQDGSVLSVPGPEGRPGFAGFPGP----AGPKGNLGSKGERGSPGPKGEKGEPGSI 948 V + D + GP G PG G PGP G KG G G+RG PG GE G+PG Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312 Query: 949 FSP-DGGALG-PAQKGAKGEPGFRGPPGP----------------------YGRPGYKGE 984 P D G G P + G KG+ G GPPGP G PG KGE Sbjct: 313 GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372 Query: 985 IGFP-----------------GRPGRPGMNGLKGEKGEPGDASLGF----GMRGMPGPPG 1023 GFP G PG PG G +G+KG+ G + G+ G PG PG Sbjct: 373 RGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPG 432 Query: 1024 PPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE-------------VGP 1070 PGPPGP G + S+ E PGPPG PG++G G +G KG+ GP Sbjct: 433 LPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGP 492 Query: 1071 PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGER------GEPGGGGFFGS--------- 1115 PG PG G+KG++G AG G + G PG GF GS Sbjct: 493 PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT 552 Query: 1116 -----------------SLPGPPGPPGPRGYPGIPGPKGE----SIRGQPGPPGPQGPPG 1154 LPG PG PG G PG+PGPKGE + +G+ GPPG G PG Sbjct: 553 FPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPG 612 Query: 1155 I-GYEGRQGPP--GPPGP------------PGPPSFPGPH---RQTISVPGPPGPPGPPG 1196 + G G GPP GPPGP PG P PGP QTI+ PG PG PG PG Sbjct: 613 LPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPG 672 Query: 1197 PPGTMG 1202 G +G Sbjct: 673 RDGDVG 678 Score = 243 bits (621), Expect = 8e-64 Identities = 158/371 (42%), Positives = 183/371 (49%), Gaps = 63/371 (16%) Query: 861 GDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGP 920 G +G +GE+G PG +G PGLPG PGP GP PGP G+ G G PGP Sbjct: 42 GIKGEKGERGFPGLEG--HPGLPGFPGPEGP--------------PGPRGQKGDDGIPGP 85 Query: 921 AGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPG 980 GPKG G G G PG G G PG +P + P G KGE GF G PG G G Sbjct: 86 PGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGI-PGCNGTKGERGFPGSPGFPGLQG 144 Query: 981 YKGEIGFPGRPGRPG---MNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYD 1037 G G PG G PG M+ L G KG PG G++G+PGP G PGP GPPG P Sbjct: 145 PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPP-GIQGLPGPTGIPGPIGPPGPP--- 200 Query: 1038 SNVFAESSRPGPPGLPGN--------QGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMK 1089 PGPPGLPG QGP G KG +G GPPGPPGQ ++ E Sbjct: 201 ----GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEF- 255 Query: 1090 GEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPG-PKGESIRGQPGPPG 1148 QKG++G PG G PPGPPG RG PG PG KGE +G+ G PG Sbjct: 256 ----------QKGDQGLPGDRG--------PPGPPGIRGPPGPPGGEKGE--KGEQGEPG 295 Query: 1149 PQGPPGIGYEGRQGPPGPPGPPGPPSFPG-PHRQTISVPGPPGPPGPPGPPGTMGASSGV 1207 +G PG +G G PG PG PG P +PG P R G G GPPGPPG + G Sbjct: 296 KRGKPG--KDGENGQPGIPGLPGDPGYPGEPGRD--GEKGQKGDTGPPGPPGLVIPRPGT 351 Query: 1208 RLWATRQAMLG 1218 + + +G Sbjct: 352 GITIGEKGNIG 362 Score = 157 bits (398), Expect = 6e-38 Identities = 119/323 (36%), Positives = 142/323 (43%), Gaps = 43/323 (13%) Query: 997 NGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQ 1056 +G+KGEKGE G L G G+PG PGP GPPGP G + PGPPG G + Sbjct: 41 SGIKGEKGERGFPGLE-GHPGLPGFPGPEGPPGPRGQK-------GDDGIPGPPGPKGIR 92 Query: 1057 GPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSS 1116 GPPG G G G PG PG G +G G G KGERG PG GF Sbjct: 93 GPPGLPGFPGTPGLPGMPGH---------DGAPGPQGIPGCNGTKGERGFPGSPGF---- 139 Query: 1117 LPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFP 1176 PG GPPGP G PG+ G G I PGP+G PG GPPG G PGP P Sbjct: 140 -PGLQGPPGPPGIPGMKGEPGSIIMSSL--PGPKGNPGY-----PGPPGIQGLPGPTGIP 191 Query: 1177 GPHRQTISVPGPPGPPGPPGPPGTMG--ASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQ 1234 GP I PGPPG GPPGPPG G + G+ + Q + P G ++EQ Sbjct: 192 GP----IGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQ 247 Query: 1235 EE-LYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPW 1293 + + V Q G + P RG PP + + P +P Sbjct: 248 KRPIDVEFQKG------DQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPG 301 Query: 1294 R-ADDILASPPRLPEPQPYPGAP 1315 + ++ P LP YPG P Sbjct: 302 KDGENGQPGIPGLPGDPGYPGEP 324 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 541 bits (1394), Expect = e-153 Identities = 373/901 (41%), Positives = 425/901 (47%), Gaps = 194/901 (21%) Query: 495 GSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGP---PGSPCLPGPPGLP-C 550 G V+ G PG + G Q G+PG+PG PGR G PG P LPG PGLP Sbjct: 635 GIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGI 694 Query: 551 PVSPLGPAGPA--LQTVPGPQGP---PGPPGRDGTPGR---DGEPGDPGEDGK------- 595 P S P P L PGP+G PGPPG GTPGR +G PG PG G Sbjct: 695 PGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFA 754 Query: 596 -PGDTGPQGFPGTPGDVGPKGDKGDPG-------------------VGERGPPGPQGPPG 635 PG GP G PG G +GPKGD+G PG VG G PGP GPPG Sbjct: 755 LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPG 814 Query: 636 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 695 PG I ++G GP G PGP G PG+ G+PGE G G DV Sbjct: 815 LPG----------IGVQGP---------PGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV 855 Query: 696 PGP------AGLPGVPGREGPPGFPGLP------------------GPPGPPGREGPPGR 731 PGP G+PG PG GPPG PGLP GPPGPPG G PGR Sbjct: 856 PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915 Query: 732 TGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGP--------PGPPGPPGPP 783 +G G G+ G G G G G G++GE GL G PGP P G PG PG P Sbjct: 916 SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975 Query: 784 GPGLPAGFDDMEGS-GGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVP 842 G P G+ + G G P S GP GP G PGL G PG+ G PG KG +G G P Sbjct: 976 GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFP 1035 Query: 843 GFPGL---PGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPG-------PV 892 G G+ PG G+ G G G G +G+KGDPG +G PGLPGP G PG P Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPG 1095 Query: 893 VYVSEQDGSVLSVPGPEGR------PGFAGFPGPAGPK---------------GNLGSKG 931 + S D + +PG G PGF G PGP GPK G +G G Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155 Query: 932 ERGSPGPKGEKGEPGSIFSPDGGALGPA-QKGAKGEPGFRGPPGPYGRPGYKGEIGFPGR 990 G PGP GEKG+PG G GPA QKG G+PGF G PGP G PG G+ G G Sbjct: 1156 HPGQPGPPGEKGKPG-----QDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGL 1209 Query: 991 PGRPGMNGLKGEKGEPGDASLGF-GMRGMPGPPGPPGP--------PGPPGTPVYDSNVF 1041 PG PG GL G KGEPG GF G++G PGPPG PGP PGP G P Sbjct: 1210 PGIPGNPGLPGPKGEPG--FHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPP------- 1260 Query: 1042 AESSRPGPPGLPGNQGPP------GPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDR 1095 RPG GLPG +GPP G KG KG G PG PG Q ++G G Sbjct: 1261 ---GRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRP 1317 Query: 1096 GDAGQKGERGEPGGGGFFG----SSLPGPPGPP------GPRGYPGIPGPKGES--IRGQ 1143 G G KG+ G PG GF G S +PG GP GP G PG+PGP G+S I+G Sbjct: 1318 GLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGD 1377 Query: 1144 PGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPH--------------------RQT 1182 GPPG G PG+ G G QGP G PGP GPP PG + T Sbjct: 1378 AGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGT 1437 Query: 1183 ISVPGPPGP---PGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYV 1239 + GPPGP GPPGPPGT + G + TR + + P+G L LYV Sbjct: 1438 RGLDGPPGPDGLQGPPGPPGTSSVAHGFLI--TRHSQTTDAPQCPQGTLQVYEGFSLLYV 1495 Query: 1240 R 1240 + Sbjct: 1496 Q 1496 Score = 535 bits (1377), Expect = e-151 Identities = 365/926 (39%), Positives = 421/926 (45%), Gaps = 193/926 (20%) Query: 423 DSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQ 482 D G G+ G R G P LP P PP G +D + Sbjct: 39 DCSGIKGEKGE---------RGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPK 89 Query: 483 TTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSP 540 G PG+ + G PG + G G KG++G PG PG PG GPPG P Sbjct: 90 GIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPP 149 Query: 541 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGP---PGPPGRDGTPGRDGEPGDPGEDGKPG 597 +PG G P + + ++PGP+G PGPPG G PG G PG G G PG Sbjct: 150 GIPGMKGEPGSI--------IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPG 201 Query: 598 DTGPQGFPGTPGD--------VGPKGDKGDPGV--------------------------- 622 GP G PG PG GPKG+KG+ G+ Sbjct: 202 LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261 Query: 623 --GERGPPGP---QGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPG 677 G+RGPPGP +GPPGPPG + +K +G G G PG PG PG Sbjct: 262 LPGDRGPPGPPGIRGPPGPPGGE-KGEK----GEQGEPGKRGKPGKDGENGQPGIPGLPG 316 Query: 678 VPGLPGEPGRFG----VNSSDVPGP-------------------AGLPGVPGREGPPGFP 714 PG PGEPGR G + PGP GLPG+PG +G GFP Sbjct: 317 DPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFP 376 Query: 715 GLPGPPGPP--------GREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAG 766 G+ GPPG P G GPPG G++G G+ G PG G PG G G GL G Sbjct: 377 GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPG-ISIPGPPGLDGQPGAPGLPG 435 Query: 767 APGPAGP----------PGPPGPPGPPGPGLPAGFDDMEGSGGP--FWSTARSADGPQGP 814 PGPAGP PGPPGPPG PG G ++G G F GP G Sbjct: 436 PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495 Query: 815 PGLPGLKGDPGVPGLPGAKGE------VGADGVPGFPGLPGREGIAGPQGPKGD------ 862 PGLPGL G PG G PG KGE G G+PG PG PG G G +G GD Sbjct: 496 PGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG 555 Query: 863 -RGSRGEKGDPGKDGV----------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGR 911 +G +GE G PG G+ G PGLPGP G PG + + E+ GP G Sbjct: 556 MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGER--------GPPGN 607 Query: 912 PGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFR- 970 PG G PG GP G G G PGP GEKG G +P P G KG+PG Sbjct: 608 PGLPGLPGNIGPMGPPGF----GPPGPVGEKGIQGVAGNPG----QPGIPGPKGDPGQTI 659 Query: 971 ---GPPGPYGRPGYKGEIGF---PGRPGRPGMNGLKGEKGEPGDASLGF-------GMRG 1017 G PG G PG G++G PG PG+PG+ G+ G KGEPG +G G G Sbjct: 660 TQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPG 719 Query: 1018 MPGPPGPP---------GPPGPPGTPVYDSNV-FAESSRPGPPGLPGNQGPPGPKGAKGE 1067 +PGPPG P GPPGPPG P FA PGPPGLPG +G GPKG +G Sbjct: 720 IPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF 779 Query: 1068 VGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPR 1127 GPPGPPG+ D L G KGD G GQ G G PG G PGPPG PGP Sbjct: 780 PGPPGPPGRTGLDGL------PGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPI 833 Query: 1128 GYPGIPGPKGESIRGQPGPPG--PQGPPG-IGYEGRQGPPGPPGPPGPPSFPGP------ 1178 G PG+ G GE +G PGPPG GPPG G G G PGP GPPG P PG Sbjct: 834 GQPGLHGIPGE--KGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGF 891 Query: 1179 --HRQTISVPGPPGPPGPPGPPGTMG 1202 + + + GPPGPPGP G PG G Sbjct: 892 PGTKGEMGMMGPPGPPGPLGIPGRSG 917 Score = 528 bits (1360), Expect = e-149 Identities = 344/783 (43%), Positives = 387/783 (49%), Gaps = 131/783 (16%) Query: 508 TPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPG 567 +PG + G+KG+KGE G PG G G PG P GPPG G GP PG Sbjct: 33 SPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGP-----PG 87 Query: 568 PQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGP 627 P+G GPPG G PG G PG PG DG P GPQG PG G G +G G PG Sbjct: 88 PKGIRGPPGLPGFPGTPGLPGMPGHDGAP---GPQGIPGCNGTKGERGFPGSPGF----- 139 Query: 628 PGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGR 687 PG QGPPGPPG M+G + +L GP+G PG PGPPG+ GLPG G Sbjct: 140 PGLQGPPGPPG---------IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTG- 189 Query: 688 FGVNSSDVPGPAGLPGVPGREGPPGFPGLPGP--------------PGPPGREGPPGRTG 733 +PGP G PG PG GPPG PGLPGP G G +GPPG G Sbjct: 190 -------IPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPG 242 Query: 734 Q----------------KGSLGEAGAPGHKGSKGAPG-PAGARGESGLAGAPGPAGPPGP 776 Q +G G+ G PG G +G PG P G +GE G G PG G PG Sbjct: 243 QISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGK 302 Query: 777 PGPPGPPG-PGLPAGFDDMEGSGGPFWSTARSAD-GPQGPPGLP----------GLKGDP 824 G G PG PGLP G G G + D GP GPPGL G KG+ Sbjct: 303 DGENGQPGIPGLP-GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNI 361 Query: 825 GVPGLPGAKGEVGADGVPGFPGLPGREGIA--GPQGPKGDRGSRGEKGDPGKDGV----- 877 G+PGLPG KGE G G+ G PGLPG G A GP GP G G RG+KGD G G+ Sbjct: 362 GLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP 421 Query: 878 -------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSK 930 G PGLPGPPGP GP + S++ + PGP G PG G G G +G G K Sbjct: 422 PGLDGQPGAPGLPGPPGPAGPHIPPSDE----ICEPGPPGPPGSPGDKGLQGEQGVKGDK 477 Query: 931 GE-------RGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKG 983 G+ G GP G+ G PG + P G P QKG KG+ G GP G G PG G Sbjct: 478 GDTCFNCIGTGISGPPGQPGLPG-LPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPG 536 Query: 984 EIGFPGRPGR-------PGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTP-- 1034 GFPG G PGM G KGE G PG L G+ G PG G PG PGP G P Sbjct: 537 APGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP-GLPGTPGQDGLPGLPGPKGEPGG 595 Query: 1035 VYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGD 1094 + PG PGLPGN GP GP G GPPGP G+ + G G Sbjct: 596 ITFKGERGPPGNPGLPGLPGNIGPMGPPG----FGPPGPVGEKGIQGVAGNPGQPGIPGP 651 Query: 1095 RGDAG----QKGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIPGPKGE---SIRGQPGP 1146 +GD G Q G+ G PG G G LPG PG PG G PGIPG KGE G PGP Sbjct: 652 KGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP 711 Query: 1147 PGPQGPPGIGYEGRQGPPGPP------GPPGPPSFPGPHRQT-ISVPGPPGPPGPPGPPG 1199 PGP+G PGI G G PG P GPPGPP FPGP + ++PGPPGPPG PG G Sbjct: 712 PGPKGFPGI--PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG 769 Query: 1200 TMG 1202 +G Sbjct: 770 ALG 772 Score = 437 bits (1125), Expect = e-122 Identities = 275/644 (42%), Positives = 317/644 (49%), Gaps = 84/644 (13%) Query: 494 PGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPG--------- 544 PG + G PG V G G++G PG+PG PG GPPGSP LPG Sbjct: 836 PGLHGIPGEKGDPGPPGLDVP--GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPG 893 Query: 545 ---------PPGLPCPVSPLGPAG-PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDG 594 PPG P P+ G +G P L+ G QG PG PG G G GEPG PG G Sbjct: 894 TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG 953 Query: 595 --------KPGDTGPQGFPGTPGDVGPKGDKGDPG----VGERGPPGPQGPPGPPGPSFR 642 G+ G G PG PG GPKG +G PG G G PG GPPGP G Sbjct: 954 PMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGL 1013 Query: 643 HDKLTFIDMEG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPA-- 699 + I G G GD+ GP+G GPPGP GVPG PG PG G D P Sbjct: 1014 PGQPGLIGPPGLKGTIGDM-GFPGPQGVEGPPGPSGVPGQPGSPGLPG-QKGDKGDPGIS 1071 Query: 700 --GLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAG 757 GLPG+PG +G PG PG PG PG G G PG G G+ G G PG G G PGP G Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131 Query: 758 ARGESGLAGAPGPAGPPGP------PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGP 811 +G SG G PG G PGP PG PGPPG G D + G G + G Sbjct: 1132 PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGN 1191 Query: 812 QGPPGLPGL---KGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGP-----KGDR 863 GPPGLPGL KGD G+PG+PG G G G PGF G PG +G GP G +G + Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251 Query: 864 GSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGP 923 G+ G +G PG+ G GLPGP GPPG +G + G G+PG G PG G Sbjct: 1252 GNPGPQGPPGRPGF--QGLPGPEGPPG-----LPGNGGIKGEKGNPGQPGLPGLPGLKGD 1304 Query: 924 KGNLGSKGERGSPGPKGEKGEPGSIFSP-----DGGALGPAQKGAKGEPGFRGPPGPYGR 978 +G G +G G PG G KG+PG P G + P G +GEPG GPPGP G Sbjct: 1305 QGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGL 1364 Query: 979 PG-------YKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPP 1031 PG KG+ G PG PG+PG+ GL G +G +G+PGP GPPG PG Sbjct: 1365 PGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGP----------QGLPGPTGPPGDPGRN 1414 Query: 1032 GTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPG 1075 G P +D PG PG PG +G GP G G GPPGPPG Sbjct: 1415 GLPGFD-GAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1457 Score = 398 bits (1022), Expect = e-110 Identities = 267/677 (39%), Positives = 316/677 (46%), Gaps = 147/677 (21%) Query: 605 PGTPGDV-GPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEAL 663 PG+ D G KG+KG ERG PG +G PG PG Sbjct: 34 PGSKCDCSGIKGEKG-----ERGFPGLEGHPGLPG------------------------F 64 Query: 664 RGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP 723 GP G PGP G G G+PG PG G+ GP GLPG PG PG PG+PG G P Sbjct: 65 PGPEGPPGPRGQKGDDGIPGPPGPKGIR-----GPPGLPGFPGT---PGLPGMPGHDGAP 116 Query: 724 GREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGA------PGPAGPPGPP 777 G +G PG G KG G G+PG G +G PGP G G G G+ PGP G PG P Sbjct: 117 GPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYP 176 Query: 778 GPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVG 837 GPPG G P G GP GPPG PGL G PG PGLPG KG +G Sbjct: 177 GPPGIQGLPGPTGIP-----------------GPIGPPGPPGLMGPPGPPGLPGPKGNMG 219 Query: 838 ADGVPGFPGLPGREGIAGPQGP----------------KGDRGSRGEKGDPGKDGVGQPG 881 + G G G +G+ GP GP KGD+G G++G PG PG Sbjct: 220 LN-FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP-----PG 273 Query: 882 LPGPPGPPGPVVYVSEQDGSV-----LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSP 936 + GPPGPPG + G G G+PG G PG G G G GE+G Sbjct: 274 IRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQK 333 Query: 937 GPKGEKGEPGSIFSPDG--------GALG----PAQKGAKGEPGFRGPPGPYGRPGYKGE 984 G G G PG + G G +G P +KG +G PG +GPPG G PG Sbjct: 334 GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG-AAV 392 Query: 985 IGFPGRPGRPGMNGLKGEKGEPGDASLGF-GMRGMPGPPGPPGPPGPPGTPVYDSNVFAE 1043 +G PG PG PG G KG++G PG + G G+ G PG PG PGPPGP G + S+ E Sbjct: 393 MGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICE 452 Query: 1044 SSRPGPPGLPGNQGPPGPKGAKGEVG-------------PPGPPGQFPFDFLQLEAEMKG 1090 PGPPG PG++G G +G KG+ G PPG PG G Sbjct: 453 PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512 Query: 1091 EKGDRGDAGQKGERG------EPGGGGFFGS--------SLPGPPGP------PGPRGYP 1130 +KG++G AG G +G PG GF GS + PG G PG G P Sbjct: 513 QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572 Query: 1131 GIPGPKGESIRGQPGPPGPQGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPP 1189 G+PG G+ G PG PGP+G PG I ++G +GPPG PG PG P GP GPP Sbjct: 573 GLPGTPGQD--GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPM-------GPP 623 Query: 1190 G--PPGPPGPPGTMGAS 1204 G PPGP G G G + Sbjct: 624 GFGPPGPVGEKGIQGVA 640 Score = 394 bits (1011), Expect = e-109 Identities = 259/615 (42%), Positives = 294/615 (47%), Gaps = 121/615 (19%) Query: 445 ETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDG 504 E G+ +P LP PP P L G S+ E+ E G +PG + G Sbjct: 939 EKGSKGEPGLPGPPGPMDPNLLG------SKGEKGEP-------GLPGIPGVSGPKGYQG 985 Query: 505 SVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP-ALQ 563 PG + GL GQ G PG PGP G G PG P L GPPGL + +G GP ++ Sbjct: 986 LPGDPG----QPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVE 1041 Query: 564 TVPGPQGPPGPPGRDGTPGRDGEPGDPGED-----GKPGDTGPQGFPGTPGDVGPKGDKG 618 PGP G PG PG G PG+ G+ GDPG G PG G G PG PG+ G KG G Sbjct: 1042 GPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVG 1101 Query: 619 DPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPG 671 DPG+ G +G PG G PG PGP GP+G G Sbjct: 1102 DPGLPGLPGTPGAKGQPGLPGFPGTPGPP------------------------GPKGISG 1137 Query: 672 PPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP--GREGPP 729 PPG PG+PG PG G G PGP G G PG++G PG G G PG P G GPP Sbjct: 1138 PPGNPGLPGEPGPVG--GGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPP 1195 Query: 730 GRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPA 789 G G G G+ G PG G+ G PGP +GE G G PG GPPGPPG PGP Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGP---KGEPGFHGFPGVQGPPGPPGSPGPA------ 1246 Query: 790 GFDDMEGSGGPFWSTARSADGPQGPP------GLPGLKGDPGVPGLPGAKGEVGADGVPG 843 +EG G GPQGPP GLPG +G PG+PG G KGE G G PG Sbjct: 1247 ----LEGPKG--------NPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPG 1294 Query: 844 FPGLPGREGIAGP---QGPKGDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQD 899 PGLPG +G GP QG G G G KGDPG GV G PG+ GP G PG Sbjct: 1295 LPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSA------- 1347 Query: 900 GSVLSVPGPEGRPGFAGFPGPAGPKGNLG-SKGERGSPGPKGEKGEPGSIFSPDGGALGP 958 GPEG PG G PGP G G G S +G GP G G+PG G GP Sbjct: 1348 -------GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGL-----KGLPGP 1395 Query: 959 AQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGM 1018 +G +G PG GPPG GR G G G GR G PG+ G G +G + G Sbjct: 1396 --QGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRG----------LDGP 1443 Query: 1019 PGPPGPPGPPGPPGT 1033 PGP G GPPGPPGT Sbjct: 1444 PGPDGLQGPPGPPGT 1458 Score = 386 bits (992), Expect = e-107 Identities = 260/666 (39%), Positives = 299/666 (44%), Gaps = 151/666 (22%) Query: 680 GLPGEPGR-FGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSL 738 G P E +G + +G+ G G G PG G PG PG PG EGPPG GQKG Sbjct: 21 GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80 Query: 739 GEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSG 798 G G PG KG +G PG G G GL G PG G PGP G PG G GF G Sbjct: 81 GIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP 140 Query: 799 GPFWSTARSADGPQGPPGLPGLKGDPG---VPGLPGAKGEVGADGVPGFPGLPGREGIAG 855 G GP GPPG+PG+KG+PG + LPG KG G G PG GLPG GI G Sbjct: 141 G--------LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPG 192 Query: 856 PQGPKGDRGSRGEKGDPGKDG---------------VGQPGLPGPPGPPGPV-------- 892 P GP G G G G PG G G+ GL GPPGPPG + Sbjct: 193 PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252 Query: 893 VYVSEQDGSVLSVPGPEGRPGFAGFPGP----AGPKGNLGSKGERGSPGPKGEKGEPGSI 948 V + D + GP G PG G PGP G KG G G+RG PG GE G+PG Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312 Query: 949 FSP-DGGALG-PAQKGAKGEPGFRGPPGP----------------------YGRPGYKGE 984 P D G G P + G KG+ G GPPGP G PG KGE Sbjct: 313 GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372 Query: 985 IGFP-----------------GRPGRPGMNGLKGEKGEPGDASLGF----GMRGMPGPPG 1023 GFP G PG PG G +G+KG+ G + G+ G PG PG Sbjct: 373 RGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPG 432 Query: 1024 PPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE-------------VGP 1070 PGPPGP G + S+ E PGPPG PG++G G +G KG+ GP Sbjct: 433 LPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGP 492 Query: 1071 PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGER------GEPGGGGFFGS--------- 1115 PG PG G+KG++G AG G + G PG GF GS Sbjct: 493 PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT 552 Query: 1116 -----------------SLPGPPGPPGPRGYPGIPGPKGE----SIRGQPGPPGPQGPPG 1154 LPG PG PG G PG+PGPKGE + +G+ GPPG G PG Sbjct: 553 FPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPG 612 Query: 1155 I-GYEGRQGPP--GPPGP------------PGPPSFPGPH---RQTISVPGPPGPPGPPG 1196 + G G GPP GPPGP PG P PGP QTI+ PG PG PG PG Sbjct: 613 LPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPG 672 Query: 1197 PPGTMG 1202 G +G Sbjct: 673 RDGDVG 678 Score = 243 bits (621), Expect = 8e-64 Identities = 158/371 (42%), Positives = 183/371 (49%), Gaps = 63/371 (16%) Query: 861 GDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGP 920 G +G +GE+G PG +G PGLPG PGP GP PGP G+ G G PGP Sbjct: 42 GIKGEKGERGFPGLEG--HPGLPGFPGPEGP--------------PGPRGQKGDDGIPGP 85 Query: 921 AGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPG 980 GPKG G G G PG G G PG +P + P G KGE GF G PG G G Sbjct: 86 PGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGI-PGCNGTKGERGFPGSPGFPGLQG 144 Query: 981 YKGEIGFPGRPGRPG---MNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYD 1037 G G PG G PG M+ L G KG PG G++G+PGP G PGP GPPG P Sbjct: 145 PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPP-GIQGLPGPTGIPGPIGPPGPP--- 200 Query: 1038 SNVFAESSRPGPPGLPGN--------QGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMK 1089 PGPPGLPG QGP G KG +G GPPGPPGQ ++ E Sbjct: 201 ----GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEF- 255 Query: 1090 GEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPG-PKGESIRGQPGPPG 1148 QKG++G PG G PPGPPG RG PG PG KGE +G+ G PG Sbjct: 256 ----------QKGDQGLPGDRG--------PPGPPGIRGPPGPPGGEKGE--KGEQGEPG 295 Query: 1149 PQGPPGIGYEGRQGPPGPPGPPGPPSFPG-PHRQTISVPGPPGPPGPPGPPGTMGASSGV 1207 +G PG +G G PG PG PG P +PG P R G G GPPGPPG + G Sbjct: 296 KRGKPG--KDGENGQPGIPGLPGDPGYPGEPGRD--GEKGQKGDTGPPGPPGLVIPRPGT 351 Query: 1208 RLWATRQAMLG 1218 + + +G Sbjct: 352 GITIGEKGNIG 362 Score = 157 bits (398), Expect = 6e-38 Identities = 119/323 (36%), Positives = 142/323 (43%), Gaps = 43/323 (13%) Query: 997 NGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQ 1056 +G+KGEKGE G L G G+PG PGP GPPGP G + PGPPG G + Sbjct: 41 SGIKGEKGERGFPGLE-GHPGLPGFPGPEGPPGPRGQK-------GDDGIPGPPGPKGIR 92 Query: 1057 GPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSS 1116 GPPG G G G PG PG G +G G G KGERG PG GF Sbjct: 93 GPPGLPGFPGTPGLPGMPGH---------DGAPGPQGIPGCNGTKGERGFPGSPGF---- 139 Query: 1117 LPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFP 1176 PG GPPGP G PG+ G G I PGP+G PG GPPG G PGP P Sbjct: 140 -PGLQGPPGPPGIPGMKGEPGSIIMSSL--PGPKGNPGY-----PGPPGIQGLPGPTGIP 191 Query: 1177 GPHRQTISVPGPPGPPGPPGPPGTMG--ASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQ 1234 GP I PGPPG GPPGPPG G + G+ + Q + P G ++EQ Sbjct: 192 GP----IGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQ 247 Query: 1235 EE-LYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPW 1293 + + V Q G + P RG PP + + P +P Sbjct: 248 KRPIDVEFQKG------DQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPG 301 Query: 1294 R-ADDILASPPRLPEPQPYPGAP 1315 + ++ P LP YPG P Sbjct: 302 KDGENGQPGIPGLPGDPGYPGEP 324 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 540 bits (1391), Expect = e-153 Identities = 374/904 (41%), Positives = 426/904 (47%), Gaps = 197/904 (21%) Query: 495 GSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGP---PGSPCLPGPPGLP-C 550 G V+ G PG + G Q G+PG+PG PGR G PG P LPG PGLP Sbjct: 635 GIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGI 694 Query: 551 PVSPLGPAGPA--LQTVPGPQGP---PGPPGRDGTPGR---DGEPGDPGEDGK------- 595 P S P P L PGP+G PGPPG GTPGR +G PG PG G Sbjct: 695 PGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFA 754 Query: 596 -PGDTGPQGFPGTPGDVGPKGDKGDPG-------------------VGERGPPGPQGPPG 635 PG GP G PG G +GPKGD+G PG VG G PGP GPPG Sbjct: 755 LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPG 814 Query: 636 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 695 PG I ++G GP G PGP G PG+ G+PGE G G DV Sbjct: 815 LPG----------IGVQGP---------PGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV 855 Query: 696 PGP------AGLPGVPGREGPPGFPGLP------------------GPPGPPGREGPPGR 731 PGP G+PG PG GPPG PGLP GPPGPPG G PGR Sbjct: 856 PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915 Query: 732 TGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGP--------PGPPGPPGPP 783 +G G G+ G G G G G G++GE GL G PGP P G PG PG P Sbjct: 916 SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975 Query: 784 GPGLPAGFDDMEGS-GGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVP 842 G P G+ + G G P S GP GP G PGL G PG+ G PG KG +G G P Sbjct: 976 GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFP 1035 Query: 843 GFPGL---PGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPG-------PV 892 G G+ PG G+ G G G G +G+KGDPG +G PGLPGP G PG P Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPG 1095 Query: 893 VYVSEQDGSVLSVPGPEGR------PGFAGFPGPAGPK---------------GNLGSKG 931 + S D + +PG G PGF G PGP GPK G +G G Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155 Query: 932 ERGSPGPKGEKGEPGSIFSPDGGALGPA-QKGAKGEPGFRGPPGPYGRPGYKGEIGFPGR 990 G PGP GEKG+PG G GPA QKG G+PGF G PGP G PG G+ G G Sbjct: 1156 HPGQPGPPGEKGKPG-----QDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGL 1209 Query: 991 PGRPGMNGLKGEKGEPGDASLGF-GMRGMPGPPGPPGP--------PGPPGTPVYDSNVF 1041 PG PG GL G KGEPG GF G++G PGPPG PGP PGP G P Sbjct: 1210 PGIPGNPGLPGPKGEPG--FHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPP------- 1260 Query: 1042 AESSRPGP---PGLPGNQGPP------GPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEK 1092 RPGP GLPG +GPP G KG KG G PG PG Q ++G Sbjct: 1261 ---GRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNP 1317 Query: 1093 GDRGDAGQKGERGEPGGGGFFG----SSLPGPPGPP------GPRGYPGIPGPKGES--I 1140 G G G KG+ G PG GF G S +PG GP GP G PG+PGP G+S I Sbjct: 1318 GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIII 1377 Query: 1141 RGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPH-------------------- 1179 +G GPPG G PG+ G G QGP G PGP GPP PG + Sbjct: 1378 KGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQ 1437 Query: 1180 RQTISVPGPPGP---PGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEE 1236 T + GPPGP GPPGPPGT + G + TR + + P+G L Sbjct: 1438 PGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLI--TRHSQTTDAPQCPQGTLQVYEGFSL 1495 Query: 1237 LYVR 1240 LYV+ Sbjct: 1496 LYVQ 1499 Score = 535 bits (1377), Expect = e-151 Identities = 365/926 (39%), Positives = 421/926 (45%), Gaps = 193/926 (20%) Query: 423 DSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQ 482 D G G+ G R G P LP P PP G +D + Sbjct: 39 DCSGIKGEKGE---------RGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPK 89 Query: 483 TTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSP 540 G PG+ + G PG + G G KG++G PG PG PG GPPG P Sbjct: 90 GIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPP 149 Query: 541 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGP---PGPPGRDGTPGRDGEPGDPGEDGKPG 597 +PG G P + + ++PGP+G PGPPG G PG G PG G G PG Sbjct: 150 GIPGMKGEPGSI--------IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPG 201 Query: 598 DTGPQGFPGTPGD--------VGPKGDKGDPGV--------------------------- 622 GP G PG PG GPKG+KG+ G+ Sbjct: 202 LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261 Query: 623 --GERGPPGP---QGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPG 677 G+RGPPGP +GPPGPPG + +K +G G G PG PG PG Sbjct: 262 LPGDRGPPGPPGIRGPPGPPGGE-KGEK----GEQGEPGKRGKPGKDGENGQPGIPGLPG 316 Query: 678 VPGLPGEPGRFG----VNSSDVPGP-------------------AGLPGVPGREGPPGFP 714 PG PGEPGR G + PGP GLPG+PG +G GFP Sbjct: 317 DPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFP 376 Query: 715 GLPGPPGPP--------GREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAG 766 G+ GPPG P G GPPG G++G G+ G PG G PG G G GL G Sbjct: 377 GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPG-ISIPGPPGLDGQPGAPGLPG 435 Query: 767 APGPAGP----------PGPPGPPGPPGPGLPAGFDDMEGSGGP--FWSTARSADGPQGP 814 PGPAGP PGPPGPPG PG G ++G G F GP G Sbjct: 436 PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495 Query: 815 PGLPGLKGDPGVPGLPGAKGE------VGADGVPGFPGLPGREGIAGPQGPKGD------ 862 PGLPGL G PG G PG KGE G G+PG PG PG G G +G GD Sbjct: 496 PGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG 555 Query: 863 -RGSRGEKGDPGKDGV----------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGR 911 +G +GE G PG G+ G PGLPGP G PG + + E+ GP G Sbjct: 556 MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGER--------GPPGN 607 Query: 912 PGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFR- 970 PG G PG GP G G G PGP GEKG G +P P G KG+PG Sbjct: 608 PGLPGLPGNIGPMGPPGF----GPPGPVGEKGIQGVAGNPG----QPGIPGPKGDPGQTI 659 Query: 971 ---GPPGPYGRPGYKGEIGF---PGRPGRPGMNGLKGEKGEPGDASLGF-------GMRG 1017 G PG G PG G++G PG PG+PG+ G+ G KGEPG +G G G Sbjct: 660 TQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPG 719 Query: 1018 MPGPPGPP---------GPPGPPGTPVYDSNV-FAESSRPGPPGLPGNQGPPGPKGAKGE 1067 +PGPPG P GPPGPPG P FA PGPPGLPG +G GPKG +G Sbjct: 720 IPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF 779 Query: 1068 VGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPR 1127 GPPGPPG+ D L G KGD G GQ G G PG G PGPPG PGP Sbjct: 780 PGPPGPPGRTGLDGL------PGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPI 833 Query: 1128 GYPGIPGPKGESIRGQPGPPG--PQGPPG-IGYEGRQGPPGPPGPPGPPSFPGP------ 1178 G PG+ G GE +G PGPPG GPPG G G G PGP GPPG P PG Sbjct: 834 GQPGLHGIPGE--KGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGF 891 Query: 1179 --HRQTISVPGPPGPPGPPGPPGTMG 1202 + + + GPPGPPGP G PG G Sbjct: 892 PGTKGEMGMMGPPGPPGPLGIPGRSG 917 Score = 528 bits (1360), Expect = e-149 Identities = 344/783 (43%), Positives = 387/783 (49%), Gaps = 131/783 (16%) Query: 508 TPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPG 567 +PG + G+KG+KGE G PG G G PG P GPPG G GP PG Sbjct: 33 SPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGP-----PG 87 Query: 568 PQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGP 627 P+G GPPG G PG G PG PG DG P GPQG PG G G +G G PG Sbjct: 88 PKGIRGPPGLPGFPGTPGLPGMPGHDGAP---GPQGIPGCNGTKGERGFPGSPGF----- 139 Query: 628 PGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGR 687 PG QGPPGPPG M+G + +L GP+G PG PGPPG+ GLPG G Sbjct: 140 PGLQGPPGPPG---------IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTG- 189 Query: 688 FGVNSSDVPGPAGLPGVPGREGPPGFPGLPGP--------------PGPPGREGPPGRTG 733 +PGP G PG PG GPPG PGLPGP G G +GPPG G Sbjct: 190 -------IPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPG 242 Query: 734 Q----------------KGSLGEAGAPGHKGSKGAPG-PAGARGESGLAGAPGPAGPPGP 776 Q +G G+ G PG G +G PG P G +GE G G PG G PG Sbjct: 243 QISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGK 302 Query: 777 PGPPGPPG-PGLPAGFDDMEGSGGPFWSTARSAD-GPQGPPGLP----------GLKGDP 824 G G PG PGLP G G G + D GP GPPGL G KG+ Sbjct: 303 DGENGQPGIPGLP-GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNI 361 Query: 825 GVPGLPGAKGEVGADGVPGFPGLPGREGIA--GPQGPKGDRGSRGEKGDPGKDGV----- 877 G+PGLPG KGE G G+ G PGLPG G A GP GP G G RG+KGD G G+ Sbjct: 362 GLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP 421 Query: 878 -------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSK 930 G PGLPGPPGP GP + S++ + PGP G PG G G G +G G K Sbjct: 422 PGLDGQPGAPGLPGPPGPAGPHIPPSDE----ICEPGPPGPPGSPGDKGLQGEQGVKGDK 477 Query: 931 GE-------RGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKG 983 G+ G GP G+ G PG + P G P QKG KG+ G GP G G PG G Sbjct: 478 GDTCFNCIGTGISGPPGQPGLPG-LPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPG 536 Query: 984 EIGFPGRPGR-------PGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTP-- 1034 GFPG G PGM G KGE G PG L G+ G PG G PG PGP G P Sbjct: 537 APGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP-GLPGTPGQDGLPGLPGPKGEPGG 595 Query: 1035 VYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGD 1094 + PG PGLPGN GP GP G GPPGP G+ + G G Sbjct: 596 ITFKGERGPPGNPGLPGLPGNIGPMGPPG----FGPPGPVGEKGIQGVAGNPGQPGIPGP 651 Query: 1095 RGDAG----QKGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIPGPKGE---SIRGQPGP 1146 +GD G Q G+ G PG G G LPG PG PG G PGIPG KGE G PGP Sbjct: 652 KGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP 711 Query: 1147 PGPQGPPGIGYEGRQGPPGPP------GPPGPPSFPGPHRQT-ISVPGPPGPPGPPGPPG 1199 PGP+G PGI G G PG P GPPGPP FPGP + ++PGPPGPPG PG G Sbjct: 712 PGPKGFPGI--PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG 769 Query: 1200 TMG 1202 +G Sbjct: 770 ALG 772 Score = 440 bits (1131), Expect = e-123 Identities = 278/647 (42%), Positives = 315/647 (48%), Gaps = 87/647 (13%) Query: 494 PGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPG--------- 544 PG + G PG V G G++G PG+PG PG GPPGSP LPG Sbjct: 836 PGLHGIPGEKGDPGPPGLDVP--GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPG 893 Query: 545 ---------PPGLPCPVSPLGPAG-PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDG 594 PPG P P+ G +G P L+ G QG PG PG G G GEPG PG G Sbjct: 894 TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG 953 Query: 595 --------KPGDTGPQGFPGTPGDVGPKGDKGDPG----VGERGPPGPQGPPGPPGPSFR 642 G+ G G PG PG GPKG +G PG G G PG GPPGP G Sbjct: 954 PMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGL 1013 Query: 643 HDKLTFIDMEG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPA-- 699 + I G G GD+ GP+G GPPGP GVPG PG PG G D P Sbjct: 1014 PGQPGLIGPPGLKGTIGDM-GFPGPQGVEGPPGPSGVPGQPGSPGLPG-QKGDKGDPGIS 1071 Query: 700 --GLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAG 757 GLPG+PG +G PG PG PG PG G G PG G G+ G G PG G G PGP G Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131 Query: 758 ARGESGLAGAPGPAGPPGP------PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGP 811 +G SG G PG G PGP PG PGPPG G D + G G + G Sbjct: 1132 PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGN 1191 Query: 812 QGPPGLPGLKGD---------PGVPGLPGAKGEVGADGVPGFPGLPGREGIAGP--QGPK 860 GPPGLPGL G PG PGLPG KGE G G PG G PG G GP +GPK Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251 Query: 861 GDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGP 920 G+ G +G G PG G GLPGP GPPG +G + G G+PG G PG Sbjct: 1252 GNPGPQGPPGRPGPTGF--QGLPGPEGPPG-----LPGNGGIKGEKGNPGQPGLPGLPGL 1304 Query: 921 AGPKGNLGSKGERGSPGPKGEKGEPGSIFSP-----DGGALGPAQKGAKGEPGFRGPPGP 975 G +G G +G G PG G KG+PG P G + P G +GEPG GPPGP Sbjct: 1305 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1364 Query: 976 YGRPG-------YKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPP 1028 G PG KG+ G PG PG+PG+ GL G +G +G+PGP GPPG P Sbjct: 1365 PGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGP----------QGLPGPTGPPGDP 1414 Query: 1029 GPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPG 1075 G G P +D PG PG PG +G GP G G GPPGPPG Sbjct: 1415 GRNGLPGFD-GAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460 Score = 398 bits (1022), Expect = e-110 Identities = 267/677 (39%), Positives = 316/677 (46%), Gaps = 147/677 (21%) Query: 605 PGTPGDV-GPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEAL 663 PG+ D G KG+KG ERG PG +G PG PG Sbjct: 34 PGSKCDCSGIKGEKG-----ERGFPGLEGHPGLPG------------------------F 64 Query: 664 RGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP 723 GP G PGP G G G+PG PG G+ GP GLPG PG PG PG+PG G P Sbjct: 65 PGPEGPPGPRGQKGDDGIPGPPGPKGIR-----GPPGLPGFPGT---PGLPGMPGHDGAP 116 Query: 724 GREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGA------PGPAGPPGPP 777 G +G PG G KG G G+PG G +G PGP G G G G+ PGP G PG P Sbjct: 117 GPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYP 176 Query: 778 GPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVG 837 GPPG G P G GP GPPG PGL G PG PGLPG KG +G Sbjct: 177 GPPGIQGLPGPTGIP-----------------GPIGPPGPPGLMGPPGPPGLPGPKGNMG 219 Query: 838 ADGVPGFPGLPGREGIAGPQGP----------------KGDRGSRGEKGDPGKDGVGQPG 881 + G G G +G+ GP GP KGD+G G++G PG PG Sbjct: 220 LN-FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP-----PG 273 Query: 882 LPGPPGPPGPVVYVSEQDGSV-----LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSP 936 + GPPGPPG + G G G+PG G PG G G G GE+G Sbjct: 274 IRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQK 333 Query: 937 GPKGEKGEPGSIFSPDG--------GALG----PAQKGAKGEPGFRGPPGPYGRPGYKGE 984 G G G PG + G G +G P +KG +G PG +GPPG G PG Sbjct: 334 GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG-AAV 392 Query: 985 IGFPGRPGRPGMNGLKGEKGEPGDASLGF-GMRGMPGPPGPPGPPGPPGTPVYDSNVFAE 1043 +G PG PG PG G KG++G PG + G G+ G PG PG PGPPGP G + S+ E Sbjct: 393 MGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICE 452 Query: 1044 SSRPGPPGLPGNQGPPGPKGAKGEVG-------------PPGPPGQFPFDFLQLEAEMKG 1090 PGPPG PG++G G +G KG+ G PPG PG G Sbjct: 453 PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512 Query: 1091 EKGDRGDAGQKGERG------EPGGGGFFGS--------SLPGPPGP------PGPRGYP 1130 +KG++G AG G +G PG GF GS + PG G PG G P Sbjct: 513 QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572 Query: 1131 GIPGPKGESIRGQPGPPGPQGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPP 1189 G+PG G+ G PG PGP+G PG I ++G +GPPG PG PG P GP GPP Sbjct: 573 GLPGTPGQD--GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPM-------GPP 623 Query: 1190 G--PPGPPGPPGTMGAS 1204 G PPGP G G G + Sbjct: 624 GFGPPGPVGEKGIQGVA 640 Score = 397 bits (1019), Expect = e-110 Identities = 256/609 (42%), Positives = 291/609 (47%), Gaps = 106/609 (17%) Query: 445 ETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDG 504 E G+ +P LP PP P L G S+ E+ E G +PG + G Sbjct: 939 EKGSKGEPGLPGPPGPMDPNLLG------SKGEKGEP-------GLPGIPGVSGPKGYQG 985 Query: 505 SVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP-ALQ 563 PG + GL GQ G PG PGP G G PG P L GPPGL + +G GP ++ Sbjct: 986 LPGDPG----QPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVE 1041 Query: 564 TVPGPQGPPGPPGRDGTPGRDGEPGDPGED-----GKPGDTGPQGFPGTPGDVGPKGDKG 618 PGP G PG PG G PG+ G+ GDPG G PG G G PG PG+ G KG G Sbjct: 1042 GPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVG 1101 Query: 619 DPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPG 671 DPG+ G +G PG G PG PGP GP+G G Sbjct: 1102 DPGLPGLPGTPGAKGQPGLPGFPGTPGPP------------------------GPKGISG 1137 Query: 672 PPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP--GREGPP 729 PPG PG+PG PG G G PGP G G PG++G PG G G PG P G GPP Sbjct: 1138 PPGNPGLPGEPGPVG--GGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPP 1195 Query: 730 GRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPA 789 G G G G+ G PG G+ G PGP +GE G G PG GPPGPPG PGP Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGP---KGEPGFHGFPGVQGPPGPPGSPGP------- 1245 Query: 790 GFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPG 849 + +G+ GP R GP G GLPG +G PG+PG G KGE G G PG PGLPG Sbjct: 1246 ALEGPKGNPGPQGPPGR--PGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPG 1303 Query: 850 REGIAGP---QGPKGDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSV 905 +G GP QG G G G KGDPG GV G PG+ GP G PG Sbjct: 1304 LKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSA------------- 1350 Query: 906 PGPEGRPGFAGFPGPAGPKGNLG-SKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAK 964 GPEG PG G PGP G G G S +G GP G G+PG KG Sbjct: 1351 -GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPG-------------LKGLP 1396 Query: 965 GEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGP 1024 G G +G PGP G PG G G PG G G G G G+PG G+ G PGP G Sbjct: 1397 GPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTR----GLDGPPGPDGL 1452 Query: 1025 PGPPGPPGT 1033 GPPGPPGT Sbjct: 1453 QGPPGPPGT 1461 Score = 386 bits (992), Expect = e-107 Identities = 260/666 (39%), Positives = 299/666 (44%), Gaps = 151/666 (22%) Query: 680 GLPGEPGR-FGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSL 738 G P E +G + +G+ G G G PG G PG PG PG EGPPG GQKG Sbjct: 21 GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80 Query: 739 GEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSG 798 G G PG KG +G PG G G GL G PG G PGP G PG G GF G Sbjct: 81 GIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP 140 Query: 799 GPFWSTARSADGPQGPPGLPGLKGDPG---VPGLPGAKGEVGADGVPGFPGLPGREGIAG 855 G GP GPPG+PG+KG+PG + LPG KG G G PG GLPG GI G Sbjct: 141 G--------LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPG 192 Query: 856 PQGPKGDRGSRGEKGDPGKDG---------------VGQPGLPGPPGPPGPV-------- 892 P GP G G G G PG G G+ GL GPPGPPG + Sbjct: 193 PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252 Query: 893 VYVSEQDGSVLSVPGPEGRPGFAGFPGP----AGPKGNLGSKGERGSPGPKGEKGEPGSI 948 V + D + GP G PG G PGP G KG G G+RG PG GE G+PG Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312 Query: 949 FSP-DGGALG-PAQKGAKGEPGFRGPPGP----------------------YGRPGYKGE 984 P D G G P + G KG+ G GPPGP G PG KGE Sbjct: 313 GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372 Query: 985 IGFP-----------------GRPGRPGMNGLKGEKGEPGDASLGF----GMRGMPGPPG 1023 GFP G PG PG G +G+KG+ G + G+ G PG PG Sbjct: 373 RGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPG 432 Query: 1024 PPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE-------------VGP 1070 PGPPGP G + S+ E PGPPG PG++G G +G KG+ GP Sbjct: 433 LPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGP 492 Query: 1071 PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGER------GEPGGGGFFGS--------- 1115 PG PG G+KG++G AG G + G PG GF GS Sbjct: 493 PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT 552 Query: 1116 -----------------SLPGPPGPPGPRGYPGIPGPKGE----SIRGQPGPPGPQGPPG 1154 LPG PG PG G PG+PGPKGE + +G+ GPPG G PG Sbjct: 553 FPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPG 612 Query: 1155 I-GYEGRQGPP--GPPGP------------PGPPSFPGPH---RQTISVPGPPGPPGPPG 1196 + G G GPP GPPGP PG P PGP QTI+ PG PG PG PG Sbjct: 613 LPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPG 672 Query: 1197 PPGTMG 1202 G +G Sbjct: 673 RDGDVG 678 Score = 243 bits (621), Expect = 8e-64 Identities = 158/371 (42%), Positives = 183/371 (49%), Gaps = 63/371 (16%) Query: 861 GDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGP 920 G +G +GE+G PG +G PGLPG PGP GP PGP G+ G G PGP Sbjct: 42 GIKGEKGERGFPGLEG--HPGLPGFPGPEGP--------------PGPRGQKGDDGIPGP 85 Query: 921 AGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPG 980 GPKG G G G PG G G PG +P + P G KGE GF G PG G G Sbjct: 86 PGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGI-PGCNGTKGERGFPGSPGFPGLQG 144 Query: 981 YKGEIGFPGRPGRPG---MNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYD 1037 G G PG G PG M+ L G KG PG G++G+PGP G PGP GPPG P Sbjct: 145 PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPP-GIQGLPGPTGIPGPIGPPGPP--- 200 Query: 1038 SNVFAESSRPGPPGLPGN--------QGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMK 1089 PGPPGLPG QGP G KG +G GPPGPPGQ ++ E Sbjct: 201 ----GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEF- 255 Query: 1090 GEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPG-PKGESIRGQPGPPG 1148 QKG++G PG G PPGPPG RG PG PG KGE +G+ G PG Sbjct: 256 ----------QKGDQGLPGDRG--------PPGPPGIRGPPGPPGGEKGE--KGEQGEPG 295 Query: 1149 PQGPPGIGYEGRQGPPGPPGPPGPPSFPG-PHRQTISVPGPPGPPGPPGPPGTMGASSGV 1207 +G PG +G G PG PG PG P +PG P R G G GPPGPPG + G Sbjct: 296 KRGKPG--KDGENGQPGIPGLPGDPGYPGEPGRD--GEKGQKGDTGPPGPPGLVIPRPGT 351 Query: 1208 RLWATRQAMLG 1218 + + +G Sbjct: 352 GITIGEKGNIG 362 Score = 157 bits (398), Expect = 6e-38 Identities = 119/323 (36%), Positives = 142/323 (43%), Gaps = 43/323 (13%) Query: 997 NGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQ 1056 +G+KGEKGE G L G G+PG PGP GPPGP G + PGPPG G + Sbjct: 41 SGIKGEKGERGFPGLE-GHPGLPGFPGPEGPPGPRGQK-------GDDGIPGPPGPKGIR 92 Query: 1057 GPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSS 1116 GPPG G G G PG PG G +G G G KGERG PG GF Sbjct: 93 GPPGLPGFPGTPGLPGMPGH---------DGAPGPQGIPGCNGTKGERGFPGSPGF---- 139 Query: 1117 LPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFP 1176 PG GPPGP G PG+ G G I PGP+G PG GPPG G PGP P Sbjct: 140 -PGLQGPPGPPGIPGMKGEPGSIIMSSL--PGPKGNPGY-----PGPPGIQGLPGPTGIP 191 Query: 1177 GPHRQTISVPGPPGPPGPPGPPGTMG--ASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQ 1234 GP I PGPPG GPPGPPG G + G+ + Q + P G ++EQ Sbjct: 192 GP----IGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQ 247 Query: 1235 EE-LYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPW 1293 + + V Q G + P RG PP + + P +P Sbjct: 248 KRPIDVEFQKG------DQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPG 301 Query: 1294 R-ADDILASPPRLPEPQPYPGAP 1315 + ++ P LP YPG P Sbjct: 302 KDGENGQPGIPGLPGDPGYPGEP 324 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 536 bits (1381), Expect = e-152 Identities = 362/868 (41%), Positives = 411/868 (47%), Gaps = 153/868 (17%) Query: 455 PAPPPVTTPPLAG----GSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPG 510 P PPP PP G G + S E+ + G LPG G V PG Sbjct: 452 PPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPG 511 Query: 511 GRVKEG---------GLKGQKGEPGVPGPPGRAGPPGSPCLPGP---PGLPCPVSPLGPA 558 + ++G G KG+KG G+PGPPGR G G PG PGLP V GP Sbjct: 512 PKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQ 571 Query: 559 GPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE------DGKPGDTGPQGFPGTPGDVG 612 GP +PGP G G PG G G G G+ GE GKPGDTG QG PG G G Sbjct: 572 GPP--GLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAG 629 Query: 613 PKGDKGD------PGV-----------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSG 655 P+G+KGD PGV GE+G PGP+G G PGP I EG Sbjct: 630 PQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGP---IGPEGRD 686 Query: 656 FGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPG 715 L+ LRG +G GPPG PG+ GL G PG GV PGP G PG+PG G PG PG Sbjct: 687 GPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGP--PGPGGSPGLPGEIGFPGKPG 744 Query: 716 LPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPG 775 PGP GPPG++GP G G G+ GE G G G G PG G GE GLAG PG G G Sbjct: 745 PPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAG 804 Query: 776 PPGPPGPPGPGLPAGFDDMEGS-GGPFWSTARSAD---GPQGPPGLPGLKG----DPGVP 827 PG PG PG G +G G P R GP GPPGLPG P +P Sbjct: 805 LPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMP 864 Query: 828 GLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPP 886 G G KGE G G+PG PGL GR G GPQGP G G++G++G G G G PG PG Sbjct: 865 GEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHV 924 Query: 887 GPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPG 946 G PGP PG G PG G PG G +G G+ GE GSPGP G +G+PG Sbjct: 925 GAPGP-----------SGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPG 973 Query: 947 SIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPG--------------------YKGEIG 986 + G GP KG GEPG RG PG G G KG+ G Sbjct: 974 A-----PGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRG 1028 Query: 987 FPGRPGRPGM--------------NGLKGEKGEPGDASL-GF-------GMRGMPGPPGP 1024 PG PG PG +G G+KG PG L GF G G PG PG Sbjct: 1029 APGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGE 1088 Query: 1025 PGPPGPPGTPVY----DSNVFAE----SSRPGPPGL------------PGNQGPPGPKGA 1064 GPPG PG D N+ A+ PGPPGL PG G G +G Sbjct: 1089 RGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGK 1148 Query: 1065 KGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPP 1124 KGE GPPG PG + +GE+G G+ GQKG++G PG GF G PG PGPP Sbjct: 1149 KGEAGPPGLPGP---PGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGP--PGNPGPP 1203 Query: 1125 GPRGYPGIPGPKG-ESIRGQPGPPGPQGPPGI-------GYEGRQGPPGPPGPPGPPSFP 1176 G G G GP G + G+ GPPGPQGP G+ G EGR G PGPPG PG P Sbjct: 1204 GADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEP 1263 Query: 1177 GPHRQTISVPGPPGPPGPPGPPGTMGAS 1204 G +PGP G GPPG G G S Sbjct: 1264 G-------LPGPEGARGPPGFKGHTGDS 1284 Score = 510 bits (1313), Expect = e-144 Identities = 334/818 (40%), Positives = 384/818 (46%), Gaps = 151/818 (18%) Query: 481 EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSP 540 E+ G LPG+ S+ T R PG E G KG+KG+PG+PG PG G PG Sbjct: 838 EKGEAGPAGPPGLPGTTSLFT--PHPRMPG----EQGPKGEKGDPGLPGEPGLQGRPGEL 891 Query: 541 CLPGPPGLP----------CPVSPLGPAGPALQTVPGPQGPPGP---PGRDGTPGRDGEP 587 GP G P P + P P PGP GPPG PG GTPG+DGE Sbjct: 892 GPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGER 951 Query: 588 GDPG---EDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHD 644 G+ G E+G PG GP+G PG PG GP PG G+ G PG +G PG PGP Sbjct: 952 GEKGAAGEEGSPGPVGPRGDPGAPGLPGP------PGKGKDGEPGLRGSPGLPGPLGTKA 1005 Query: 645 KLTFI-DMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPG 703 + E GG + ++G RG PG PG PG G PG + + PGP+G PG Sbjct: 1006 ACGKVRGSENCALGG--QCVKGDRGAPGIPGSPGSRGDPG------IGVAGPPGPSGPPG 1057 Query: 704 VPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGA-------------------- 743 G G G PG PGP GP GR+G PG G++G G+ G Sbjct: 1058 DKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDC 1117 Query: 744 ----------PGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDD 793 PG KG KG PG G G G G GP G PGPPG GP G G D Sbjct: 1118 PPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADG 1177 Query: 794 MEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGI 853 G G QG PG+PG G PG PG PGA G GA G PG G PG+EG Sbjct: 1178 EVGQ-----------KGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGP 1226 Query: 854 AGPQGPKGDRGSRGEKGDPGKDG----------VGQPGLPGPPGPPGPVVYVSEQDGSVL 903 GPQGP G G GE+G G+DG G+PGLPGP G GP + S Sbjct: 1227 PGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDS-- 1284 Query: 904 SVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPD-----GGALGP 958 PGP G G G PG G G G G G GP+G +G PG SP G + P Sbjct: 1285 GAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTP 1344 Query: 959 AQKGAKGE------PGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLG 1012 QKG+KGE PGF GP GP G PG KG G G PG+PG G KGE+G+PG Sbjct: 1345 GQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPG----- 1399 Query: 1013 FGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPG 1072 ++G GPPG G PG PG P + + + GP GLPG GP GP G G+ G PG Sbjct: 1400 --IKGDKGPPGGKGQPGDPGIPGHKGH----TGLMGPQGLPGENGPVGPPGPPGQPGFPG 1453 Query: 1073 PPGQFP-FDFL----------QLE------------AEMKGEKGDRGDAGQKGERGEPGG 1109 G+ P + L QLE A MK +G G G G+ G PG Sbjct: 1454 LRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGR 1513 Query: 1110 GGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGP 1169 G G PG PG G G G GPKGE RG G PG PG+G G GPPG PG Sbjct: 1514 AGPMGE--PGRPGQGGLEGPSGPIGPKGE--RGAKGDPGA---PGVGLRGEMGPPGIPGQ 1566 Query: 1170 PGPPSF--------PGPHRQTISVPGPPGPPGPPGPPG 1199 PG P + PGP +T G PG PGPPGPPG Sbjct: 1567 PGEPGYAKDGLPGIPGPQGET-GPAGHPGLPGPPGPPG 1603 Score = 501 bits (1290), Expect = e-141 Identities = 333/822 (40%), Positives = 383/822 (46%), Gaps = 129/822 (15%) Query: 517 GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPG 576 GL+G G PGVPGPPG G PG P G PG P P P GP G GP GPPGPPG Sbjct: 711 GLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGK-----DGPNGPPGPPG 765 Query: 577 RDGTPGRDGEPGDPGEDG------------KPGDTGPQGFPGTPGDVGPKGDKGDPGV-- 622 G PG GE G PG+ G +PG+ G G PG PG G +G+KGD G Sbjct: 766 TKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKG 825 Query: 623 -----------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPG 671 GE+G GP GPPG PG T + G+ +GP+G G Sbjct: 826 ELGLPGLKGDRGEKGEAGPAGPPGLPGT-------TSLFTPHPRMPGE----QGPKGEKG 874 Query: 672 PPGPPGVPGLPGEPGRFGVNSSDVP-------GPAGLPGVPGREGPPGFPGLPGPPGPPG 724 PG PG PGL G PG G P G G PG G G PG G PGP GPPG Sbjct: 875 DPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPG 934 Query: 725 REGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGP-----PGPPGP 779 G PG G G GE G G G +G+PGP G RG+ G G PGP G PG G Sbjct: 935 SVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGS 994 Query: 780 PGPPGP-GLPAGFDDMEGS-----GGPFWSTARSADGPQGPPGLPGLKGDPG--VPGLPG 831 PG PGP G A + GS GG + G G PG PG +GDPG V G PG Sbjct: 995 PGLPGPLGTKAACGKVRGSENCALGG---QCVKGDRGAPGIPGSPGSRGDPGIGVAGPPG 1051 Query: 832 AKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPG------- 884 G G G PG GLPG G GP G G G+ GE+G PGK G+ PG Sbjct: 1052 PSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAK 1111 Query: 885 ------PPGPPG-PVVYVSEQDGSVLSVPGPEGR---------PGFAGFPGPAGPKGNLG 928 PPGPPG P + + D V PG EG PG G PG AGP+G+ G Sbjct: 1112 DVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQG 1171 Query: 929 SKGERGSPGPKGEKGEPG--SIFSPDGGALGPAQKG---AKGEPGFRGPPGPYGRPGYKG 983 +G G G KG++G PG P G P G A G PG +G PG G PG +G Sbjct: 1172 ERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQG 1231 Query: 984 EIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAE 1043 G PG PG G G G+ G PG+ G G PG PGP G GPPG + + A Sbjct: 1232 PSGLPGIPGEEGKEGRDGKPGPPGEP----GKAGEPGLPGPEGARGPPGFKGHTGDSGAP 1287 Query: 1044 SSR--------PGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDR 1095 R PG GLPG G GP G +G GP GPPG+ GE G Sbjct: 1288 GPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGK------NGSPGSPGEPGPS 1341 Query: 1096 GDAGQKGERGEPGGGGFFGSSLP-GPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG 1154 G GQKG +GE G G G P GPPG PG +G PG G G+ G+PG G +G PG Sbjct: 1342 GTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKP--GEPGFKGERGDPG 1399 Query: 1155 IGYEGRQGPPGPPGPPGPPSFPGPHRQT-----ISVPG------PPGPPGPPGPPGTMGA 1203 I +G +GPPG G PG P PG T +PG PPGPPG PG PG G Sbjct: 1400 I--KGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGE 1457 Query: 1204 SSGVR-LWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNG 1244 S + L Q LG+ E +L+ A+ Y++ G Sbjct: 1458 SPSMETLRRLIQEELGKQLETRLAYLL--AQMPPAYMKSSQG 1497 Score = 470 bits (1209), Expect = e-132 Identities = 335/848 (39%), Positives = 382/848 (45%), Gaps = 161/848 (18%) Query: 419 EEGDDSDGASGDSG-SGL-GDARELLREETGAALKPRLPAPPPVTTP-PLAGGSSTEDSR 475 E+GD G G+ G GL GD E + E G A P LP + TP P G E Sbjct: 817 EKGDQ--GEKGELGLPGLKGDRGE--KGEAGPAGPPGLPGTTSLFTPHPRMPG---EQGP 869 Query: 476 SEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPG---P 530 E + G Q PG G PG + +EG G G G PG PG Sbjct: 870 KGEKGDPGLPGEPGLQGRPGELGPQ---GPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGA 926 Query: 531 PGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQT-VPGPQGPPGPPGRDGTPG-----RD 584 PG +GPPGS PG G P G G A + PGP GP G PG G PG +D Sbjct: 927 PGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKD 986 Query: 585 GEPGDPGEDGKPGDTGPQ--------------------GFPGTPGDVGPKGDKGDPGVGE 624 GEPG G G PG G + G G PG G G +GDPG+G Sbjct: 987 GEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGV 1046 Query: 625 RGPPGPQGPPGPPGPSFRHDKLTFIDMEG----SGFGGDLEALRGPRGFPG--------- 671 GPPGP GPPG G F +G G G+ RGP G PG Sbjct: 1047 AGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGN-PGERGPPGKPGLSSLLSPGD 1105 Query: 672 ------------PPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPG- 718 PPGPPG+PGLPG G GV PG G G G GPPG PG PG Sbjct: 1106 INLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGK--PGREGTEGKKGEAGPPGLPGPPGI 1163 Query: 719 --PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGP 776 P G G G G GQKG G G PG G G PGP GA G +G AG PG G PG Sbjct: 1164 AGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGK 1223 Query: 777 PGPPGPPGP-GLPA-----GFDDMEGSGGPFWSTARSAD----GPQGPPGLPGLKGDPGV 826 GPPGP GP GLP G + +G GP ++ + GP+G G PG KG G Sbjct: 1224 EGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGD 1283 Query: 827 PGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGV-GQPGLPGP 885 G PG +GE GA G+PG GLPG++G GP GP+G +G RG PGK+G G PG PGP Sbjct: 1284 SGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGP---PGKNGSPGSPGEPGP 1340 Query: 886 PGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKG---------ERGSP 936 G PG Q GS G G PG GF GP GP G G KG + G P Sbjct: 1341 SGTPG-------QKGS----KGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEP 1389 Query: 937 GPKGEKGEPG--SIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRP 994 G KGE+G+PG P GG P G G G G GP G PG G +G PG PG+P Sbjct: 1390 GFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQP 1449 Query: 995 GMNGLKGEK--------------GEPGDASLGFGMRGMP--------GPPGPPGPPGPPG 1032 G GL+GE G+ + L + + MP G PGPPGPPG G Sbjct: 1450 GFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDG 1509 Query: 1033 TPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEK 1092 P + E RPG GL G GP GPKG +G G PG PG Sbjct: 1510 LPGR-AGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGV---------------- 1552 Query: 1093 GDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPG---PRGYPGIPGPKGESIRGQPGPPGP 1149 G RG+ G G G+PG G+ LPG PGP G P G+PG+PGP PGPPG Sbjct: 1553 GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGP--------PGPPGQ 1604 Query: 1150 QGPPGIGY 1157 P Y Sbjct: 1605 CDPSQCAY 1612 Score = 249 bits (635), Expect = 2e-65 Identities = 181/534 (33%), Positives = 219/534 (41%), Gaps = 139/534 (26%) Query: 426 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTT- 484 G GD G RE + G A P LP PP + P + G D + +Q Sbjct: 1129 GFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHP 1188 Query: 485 -----VASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAG-- 535 + G PG+D ++ G G KEG G +G G PG+PG G+ G Sbjct: 1189 GVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRD 1248 Query: 536 ----PPGSPCLPGPPGLPCPVSPLGPAG----------------------PALQTVPG-- 567 PPG P G PGLP P GP G P + +PG Sbjct: 1249 GKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKD 1308 Query: 568 ----------PQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDK 617 PQGP GPPG++G+PG GEPG G G+ G G G PG PG +GP+G Sbjct: 1309 GDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPP 1368 Query: 618 GDPGVGERGPPGPQGPPGPPG-PSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPP 676 G+PG E+G PG +G PG PG P F+ ++ GD ++G +G PG G P Sbjct: 1369 GEPG--EKGVPGKEGVPGKPGEPGFKGER------------GD-PGIKGDKGPPGGKGQP 1413 Query: 677 GVPGLPGEPGRFGV-NSSDVPGPAGLPGVPGREGPPGFPGL------------------- 716 G PG+PG G G+ +PG G G PG G PGFPGL Sbjct: 1414 GDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELG 1473 Query: 717 -------------------------PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKG 751 PGPPGPPG++G PGR G G G G G +G G Sbjct: 1474 KQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSG 1533 Query: 752 APGPAGARGESGLAGAPGPA-----GPPGPPGPPGPPG---PGLPAGFDDMEGSGGPFWS 803 GP G RG G GAPG GPPG PG PG PG GLP Sbjct: 1534 PIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLP--------------- 1578 Query: 804 TARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREG-IAGP 856 G GP G G G PG+PG PG G+ F L R G + GP Sbjct: 1579 ------GIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKGP 1626 Score = 131 bits (330), Expect = 4e-30 Identities = 100/259 (38%), Positives = 119/259 (45%), Gaps = 50/259 (19%) Query: 957 GPAQKGAKGEPGFRGPPGPYGRPGYKG--EIGFPGRPGRPGMNGLKGEKGEPGDASLGFG 1014 GP Q EP PP P RP G +IGF + GEKGE G A G Sbjct: 441 GPCQVTVVTEPP---PPPPPQRPPTPGSEQIGFLKTIN---CSCPAGEKGEMGVA----G 490 Query: 1015 MRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQG----PPGPKGAKGEVGP 1070 G+PGP G G GP G P GP G G+ G G KG KG +G Sbjct: 491 PMGLPGPKGDIGAIGPVGAP-------------GPKGEKGDVGIGPFGQGEKGEKGSLGL 537 Query: 1071 PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYP 1130 PGPPG+ G KG RG+ G+ GE G PG G G GPPG PGP G Sbjct: 538 PGPPGR------------DGSKGMRGEPGELGEPGLPGEVGMRGPQ--GPPGLPGPPGRV 583 Query: 1131 GIPGPKGESIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPP 1189 G PG +GE RG+ G G +G G+ G+ G+ G G G PGP GP + G Sbjct: 584 GAPGLQGE--RGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEK----GDV 637 Query: 1190 GPPGPPGPPGTMGASSGVR 1208 GP GPPG PG++ G++ Sbjct: 638 GPAGPPGVPGSVVQQEGLK 656 Score = 33.9 bits (76), Expect = 1.2 Identities = 56/218 (25%), Positives = 73/218 (33%), Gaps = 37/218 (16%) Query: 46 PEPQGP--LPVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAP 103 P PQGP LP P + G PG P P + E G P A P Sbjct: 1227 PGPQGPSGLPGIPGEE---------GKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGF 1277 Query: 104 EENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQE 163 + + GA G + +P + +T P GP GP P + Sbjct: 1278 KGHTGDSGAPGPRGESGAMGLPG--QEGLPGKD---GDT----GPTGPQGPQGPRGPPGK 1328 Query: 164 NGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWAP-LTGPSVPP--PSSERISE 220 NG S G P PG T P S G P P GP PP P + + Sbjct: 1329 NG-----SPGSPGEPGPSGT-----PGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPG 1378 Query: 221 EVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQ 258 + G+ G+P + + D G+ GP GQ Sbjct: 1379 KEGVPGKPGEPG----FKGERGDPGIKGDKGPPGGKGQ 1412 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 533 bits (1374), Expect = e-151 Identities = 395/1022 (38%), Positives = 445/1022 (43%), Gaps = 176/1022 (17%) Query: 421 GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 480 G S GA G+SG + G + PP T P G D Sbjct: 557 GPGSSGAKGESG------------DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPG 604 Query: 481 EQTTVASLGAQTLPG--SDSVSTWDGSVRTPGGRVKEGGLKGQKGE------PGVPGPPG 532 E G LPG D + + P G + G++G+ GE PG GP G Sbjct: 605 EPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG 664 Query: 533 RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE 592 GP G+P PG PG+ P GP G GPQG PGPPG+ G PG G PG G Sbjct: 665 LLGPRGTPGAPGQPGMAGVDGPPGPKGNM-----GPQGEPGPPGQQGNPGPQGLPGPQGP 719 Query: 593 DGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDK 645 G PG+ GPQG PG G G G G PG G GPPGPQGP G PGP Sbjct: 720 IGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 779 Query: 646 LTFIDMEGS----------GFGGDLEALR--------GPRGFPGPPGPPGVPGLPGEPGR 687 ++GS GF GD+ GPRG GP GP G G G+PG Sbjct: 780 DGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 839 Query: 688 FG-VNSSDVPGPAGLPGVPGREGP------PGFPG---------LPGPPGPPGREGPPGR 731 G G GLPG PGR+GP PGFPG + G PGP G+ GP G Sbjct: 840 SGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGP 899 Query: 732 TGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGL 787 G +G+ G G PG KG+ G GP G GE G G GP G PGP GPPGPPG PG Sbjct: 900 RGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGH 959 Query: 788 PA-----GFDDMEGSGGPFWSTARSADGPQGPPGLPGL---KGDPGVPGLPGAKGEVGAD 839 P GF G GP GPQGP G G +G PG PG PG +G GA Sbjct: 960 PGQRGETGFQGKTGPPGP-----GGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 1014 Query: 840 GVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQ 898 G G G PG +GI+G GP G RG GE+G PG G G G GP GPPGPV E+ Sbjct: 1015 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1074 Query: 899 DGSVLSVP-GPEGRPGFAGFPGPAGPKGNLGSKGERGS------------PGPKGEKGEP 945 + + P G GRPG G PGPAG KG G KG +G PGP G G P Sbjct: 1075 GSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSP 1134 Query: 946 GSIFSPDGGALG-PAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG 1004 G D G +G P QKG+KG+ G GPPGP G G G G G G PG G +G G Sbjct: 1135 GE--DGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFG 1192 Query: 1005 EPGDASLGFGMRGMPGPPGP---PGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGP 1061 + GD G RG PGPPGP G PGPPG + +V GPPG PG +GP GP Sbjct: 1193 QKGDE----GARGFPGPPGPIGLQGLPGPPGEKGENGDV----GPMGPPGPPGPRGPQGP 1244 Query: 1062 KGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFG------- 1114 GA G GPPG G GEKG+ G+AG G GE G GG G Sbjct: 1245 NGADGPQGPPGSVGS---------VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGE 1295 Query: 1115 SSLPGPPGPPGPRGYPGIPGPKGE----SIRGQPGPPGPQGPPGI----GYEGRQGPPGP 1166 + PG GPPG +G PG GPKG G PGPPG GP G G +G G PG Sbjct: 1296 AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1355 Query: 1167 PGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEV--- 1223 PGPPGP GPPGPPG GPPG GA RQ G E Sbjct: 1356 PGPPGPSG----------EAGPPGPPGKRGPPGAAGAEG-------RQGEKGAKGEAGAE 1398 Query: 1224 -PEGWLIFVAEQEELYVRVQNGFRKVQ---LEARTPLPRGTDNEVAALQPPVVQLHDSNP 1279 P G V Q G R + E P G D + PP + +P Sbjct: 1399 GPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP 1458 Query: 1280 YPRREHPHPTARPWRADDILASPP---------RLPEPQPYPGAPHHSSYVHLRPARPTS 1330 + E HP L PP LP Q PGA PA P Sbjct: 1459 GSKGEKGHPGLIG------LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIP--GPAGPLG 1510 Query: 1331 PP 1332 PP Sbjct: 1511 PP 1512 Score = 528 bits (1359), Expect = e-149 Identities = 340/784 (43%), Positives = 380/784 (48%), Gaps = 113/784 (14%) Query: 485 VASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPG 544 V +G + G + G PG + G KG+ G PG+PG PGR GP GS PG Sbjct: 813 VGQIGPRGEDGPEGPKGRAGPTGDPGPS-GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPG 871 Query: 545 PPGL------------PCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE 592 PG P P GP GP + G +GP G PG GT G DG PG PGE Sbjct: 872 FPGANGEKGARGVAGKPGPRGQRGPTGP--RGSRGARGPTGKPGPKGTSGGDGPPGPPGE 929 Query: 593 DGKPGDTGPQGFPGTPGDVGPKGDKGDPG-VGERGPPGPQGPPGPPGPSFRHDKLTFIDM 651 G G GP GFPG G GP G G PG G+RG G QG GPPGP + Sbjct: 930 RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG------GVVGP 983 Query: 652 EG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP-------GPAGLPG 703 +G +G G + G RG PGPPGPPG GLPG G+ G P GPAGL G Sbjct: 984 QGPTGETGPI----GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG 1039 Query: 704 VPGREGPPGFPGLPG------PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAG 757 PG G PG G PG P GPPG G PG G G+ G G PG G +G PGPAG Sbjct: 1040 FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG 1099 Query: 758 ARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGG----PFWSTARSADGPQG 813 +G G G GPAG G GP G PGP PAG +G G P ++ G G Sbjct: 1100 EKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1159 Query: 814 PPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPG 873 PPG PGL+G G PG+ G GE G G G G G EG G GP G G +G G PG Sbjct: 1160 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1219 Query: 874 KDG----VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKG---- 925 + G VG G PGPPGP GP +G+ GP+G PG G G G KG Sbjct: 1220 EKGENGDVGPMGPPGPPGPRGP----QGPNGA----DGPQGPPGSVGSVGGVGEKGEPGE 1271 Query: 926 --NLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKG 983 N G GE G GPKGE+GE G P GA GP GAKG PG GP G G G+ G Sbjct: 1272 AGNPGPPGEAGVGGPKGERGEKGEAGPP--GAAGPP--GAKGPPGDDGPKGNPGPVGFPG 1327 Query: 984 EIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAE 1043 + G PG PG G +G+ G+KGE GD G PGPPGP G GPPG P Sbjct: 1328 DPGPPGEPGPAGQDGVGGDKGEDGDP-------GQPGPPGPSGEAGPPGPP--------- 1371 Query: 1044 SSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGE 1103 + GPPG G +G G KGAKGE G GPPG+ Q A G +G RG G GE Sbjct: 1372 -GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGE 1430 Query: 1104 RGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGES----------------IRGQPGPP 1147 +G PG G G PGP GPPG G G PG KGE +G G P Sbjct: 1431 QGLPGAAGQDGP--PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1488 Query: 1148 GPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPH--RQTISVPGP---------PGPPGPP 1195 G QG PG G G GP GP GPPGPP PGP + GP PGPPG P Sbjct: 1489 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP 1548 Query: 1196 GPPG 1199 GPPG Sbjct: 1549 GPPG 1552 Score = 496 bits (1277), Expect = e-140 Identities = 339/846 (40%), Positives = 385/846 (45%), Gaps = 187/846 (22%) Query: 509 PGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPL----------GPA 558 P G G G +G G PG PG GPPG P LPG GLP P + G Sbjct: 458 PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 517 Query: 559 GP------------------ALQTVPGPQ------GPPGPPGRDGTPGRDGEP------- 587 GP AL+ PGP GP G PG G G G+P Sbjct: 518 GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 577 Query: 588 --------GDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV----GERGPPGPQGPPG 635 G PG+ G+PG G +G PG PG G +G G PG+ G RG GPQGPPG Sbjct: 578 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 637 Query: 636 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 695 PPG + I G L GPRG PG PG PG+ G+ G PG G Sbjct: 638 PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKG-----N 692 Query: 696 PGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGP 755 GP G PG PG++G PG GLPGP GP GPPG G +G G AG PG G G PG Sbjct: 693 MGPQGEPGPPGQQGNPGPQGLPGPQGP---IGPPGEKGPQGKPGLAGLPGADGPPGHPGK 749 Query: 756 AGARGESGLAGAPGPAGPPGPPGPPGPPG----------------PGLPAGFDDM--EGS 797 G GE G G PGP GP G PGP G G G P DM +G Sbjct: 750 EGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGD 809 Query: 798 GGPFWSTA-RSADGPQGPPGLPGLKGD---------------PGVPGLPGAKGEVGADGV 841 G R DGP+GP G G GD PG+PG PG +G G+ G Sbjct: 810 RGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 869 Query: 842 PGFPGL------------PGREGIAGPQGPKGDRGSRGEKGDPGKDGV-------GQPGL 882 PGFPG PG G GP GP+G RG+RG G PG G G PG Sbjct: 870 PGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGE 929 Query: 883 PGPPGPPGPVVYVSE--------QDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERG 934 GP GP GPV + +DG + PG G GF G GP GP G +G +G G Sbjct: 930 RGPQGPQGPVGFPGPKGPPGPPGKDG-LPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTG 988 Query: 935 SPGPKGEKGEPGSIFSP-DGGALGPAQK-GAKGEP---GFRGPPGPYGRPGYKGEIGFPG 989 GP GE+G PG P + G G A K GAKG+P G G GP G G+ GE G PG Sbjct: 989 ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 1048 Query: 990 RPGRPGMNGLKGEKGEPGD-------ASLG-FGMRGMPGPPGPPGPPGPPGTPVYDSNVF 1041 G PG+ G +G +G PG S G G G+PG PGP GPPGP G Sbjct: 1049 AQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG--------- 1099 Query: 1042 AESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQK 1101 G PG G QGP G G +G VG PGP G A GE GD+G+ G+ Sbjct: 1100 ----EKGAPGEKGPQGPAGRDGVQGPVGLPGPAG---------PAGSPGEDGDKGEIGEP 1146 Query: 1102 GERGEPGGGGFFGSSLPGPPGPPGPRGYPGI------PGPKG----------ESIRGQPG 1145 G++G G G G PGPPG GP G PGI PGP+G E RG PG Sbjct: 1147 GQKGSKGDKGENGP--PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1204 Query: 1146 PPGP---QGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTM 1201 PPGP QG PG G +G G GP GPPGPP GP GP G GP GPPG++ Sbjct: 1205 PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ-------GPNGADGPQGPPGSV 1257 Query: 1202 GASSGV 1207 G+ GV Sbjct: 1258 GSVGGV 1263 Score = 436 bits (1121), Expect = e-122 Identities = 333/880 (37%), Positives = 384/880 (43%), Gaps = 166/880 (18%) Query: 571 PPGPPGRDGTPGRDGEPG----DPGEDGKPGDTGPQGFPGT--PGDV--GPKGDKGDPGV 622 P PP + PG E G G+ G +G P PG + GP G G G+ Sbjct: 405 PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 464 Query: 623 GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLP 682 GPPG QGP GPPG G RG PG PG PG GLP Sbjct: 465 --MGPPGLQGPTGPPGDP------------------------GDRGPPGRPGLPGADGLP 498 Query: 683 GEPG-------RFGVNSSDVP---------------------GPAGLPGVPGREGPPGFP 714 G PG R+G + S P GP G G+ GR GP G P Sbjct: 499 GPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGP 558 Query: 715 GL---------PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLA 765 G PGP GP G +GPPG TG+ G G GA G +G G PG G RG GL Sbjct: 559 GSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLP 618 Query: 766 GAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGG-------PFWSTARSADGPQGPPGLP 818 G PG G G GP GPPG P G D M G G P + R GP+G PG P Sbjct: 619 GLPGDKGHRGERGPQGPPG---PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAP 675 Query: 819 GLKGDPGVPGLPGAKGEVGADGVPGFPGL---PGREGIAGPQGPKGDRGSRGEKGDPGKD 875 G G GV G PG KG +G G PG PG PG +G+ GPQGP G G +G +G PG Sbjct: 676 GQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLA 735 Query: 876 GVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGS 935 G+ PG GPPG PG E+ L PGP+G G+PGP G KG G +G +GS Sbjct: 736 GL--PGADGPPGHPGKEGQSGEK--GALGPPGPQGP---IGYPGPRGVKGADGVRGLKGS 788 Query: 936 PGPKGEKGEPGSIFSPDGGALGP----AQKGAKGEPGFRGP---------PGPYGRPGYK 982 G KGE G PG F D G G Q G +GE G GP PGP G+ G K Sbjct: 789 KGEKGEDGFPG--FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEK 846 Query: 983 GEIGFPGRPGRPGMNGLKGEKGEPG--DASLGFGMRGMPGPPGPPGPPGPPGT------- 1033 G++G PG PG PG G KG G PG A+ G RG+ G PGP G GP G Sbjct: 847 GKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGAR 906 Query: 1034 -PVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEK 1092 P S GPPG PG +GP GP+G G GP GPPG D L G Sbjct: 907 GPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL------PGHP 960 Query: 1093 GDRGDAGQKGERGEPGGGGFFG-------------SSLPGPPGPPGPRGYPGI------- 1132 G RG+ G +G+ G PG GG G PGPPGPPG +G PG Sbjct: 961 GQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAK 1020 Query: 1133 --PGPKGES-------IRGQPGP---PGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPH 1179 PGP+G S +RG PG PG QG PG+ G EG QGPPGP G PG G Sbjct: 1021 GDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGT- 1079 Query: 1180 RQTISVPGPPGPPGPPGPPGTMGA--SSGVRLWATRQAMLGQV----HEVPEGWLIFVAE 1233 I +PG PGP GPPGP G GA G + A R + G V P G + Sbjct: 1080 AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGD 1139 Query: 1234 QEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPW 1293 + E+ Q G + + E P P G V A P + D P PR + + Sbjct: 1140 KGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGA---PGIAGGDGEPGPRGQQGMFGQKGD 1196 Query: 1294 RADDILASPPRLPEPQPYPGAP-HHSSYVHLRPARPTSPP 1332 PP Q PG P + P P PP Sbjct: 1197 EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPP 1236 Score = 362 bits (929), Expect = 2e-99 Identities = 236/553 (42%), Positives = 260/553 (47%), Gaps = 103/553 (18%) Query: 489 GAQTLPGSDSVSTWDGSVRT---PGGRVKEG-----GLKGQKGEPGVPGPPGRAGPPGSP 540 GA+ PG +S DG PG R G GLKG +G G PGP G G GS Sbjct: 1018 GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA 1077 Query: 541 CLPGPPGLPCPVSPLGPAGPALQT-VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT 599 GP GLP P GP GPA + PG +GP GP GRDG G G PG G G PG+ Sbjct: 1078 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGED 1137 Query: 600 GPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS-GFGG 658 G +G G PG G KGDKG+ G GPPG QGP G PG + + +G G G Sbjct: 1138 GDKGEIGEPGQKGSKGDKGENG--PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKG 1195 Query: 659 DLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPG 718 D G RGFPGPPGP G+ GLPG PG G N DV GP G PG PG GP G G G Sbjct: 1196 D----EGARGFPGPPGPIGLQGLPGPPGEKGENG-DV-GPMGPPGPPGPRGPQGPNGADG 1249 Query: 719 PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPG 778 P GPPG G G G+KG GEAG PG G G GP G RGE G AG PG AGPPG G Sbjct: 1250 PQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG 1309 Query: 779 PPG------------------PPGPGLPAGFDDMEGS----GGPFWSTARSADGPQGPPG 816 PPG PPG PAG D + G G P G GPPG Sbjct: 1310 PPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG 1369 Query: 817 LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGP----------------- 859 PG +G PG G G +GE GA G G G PG+ G GPQGP Sbjct: 1370 PPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG 1429 Query: 860 -------------------------KGDRGSRGEKGDPGKDGV----------GQPGLPG 884 KGD GS+GEKG PG G+ G GLPG Sbjct: 1430 EQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1489 Query: 885 PPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGS------KGERGSPGP 938 G PG ++ DG + GP G PG G PGP GPKGN GS KG+ G PGP Sbjct: 1490 TQGSPG-----AKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP 1544 Query: 939 KGEKGEPGSIFSP 951 G G PG + P Sbjct: 1545 PGSPGPPGEVIQP 1557 Score = 347 bits (891), Expect = 4e-95 Identities = 226/509 (44%), Positives = 251/509 (49%), Gaps = 84/509 (16%) Query: 459 PVTTPPLAG--GSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPG------ 510 PV P AG GS ED E+ E S G + G G V PG Sbjct: 1121 PVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1180 Query: 511 --GRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP---VSPLGPAGPALQTV 565 G + G+ GQKG+ G G PG GP G LPGPPG V P+GP GP Sbjct: 1181 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP----- 1235 Query: 566 PGPQGPPGPPGRDGT---PGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV 622 PGP+GP GP G DG PG G G GE G+PG+ G G PG G GPKG++G+ G Sbjct: 1236 PGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG- 1294 Query: 623 GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLP 682 E GPPG GPPG GP G D GP+G PGP G PG PG P Sbjct: 1295 -EAGPPGAAGPPGAKGPP----------------GDD-----GPKGNPGPVGFPGDPGPP 1332 Query: 683 GEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAG 742 GEPG PAG GV G +G G PG PGPPGP G GPPG G++G G AG Sbjct: 1333 GEPG-----------PAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAG 1381 Query: 743 APGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFW 802 A G +G KGA G AGA G G G GP GP G PGP G G P G + G+ G Sbjct: 1382 AEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAG--- 1438 Query: 803 STARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGD 862 GP GPPGLPGLKGD PG+KGE G PGL G G G QG KGD Sbjct: 1439 --QDGPPGPMGPPGLPGLKGD------PGSKGE------KGHPGLIGLIGPPGEQGEKGD 1484 Query: 863 RGSRGEKGDPGKDGVGQ-PGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPA 921 RG G +G PG G G PG GP GPPGP +PGP+G G G GPA Sbjct: 1485 RGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP-----------GLPGPQGPKGNKGSTGPA 1533 Query: 922 GPKGNLGSKGERGSPGPKGEKGEPGSIFS 950 G KG+ G G GSPGP GE +P I S Sbjct: 1534 GQKGDSGLPGPPGSPGPPGEVIQPLPILS 1562 Score = 52.4 bits (124), Expect = 3e-06 Identities = 45/172 (26%), Positives = 71/172 (41%), Gaps = 10/172 (5%) Query: 247 AYVFGPDANSGQVARYHFPS-LFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKL 305 AY A + FP F DFS+LF ++P L +I + G++ Sbjct: 73 AYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYNEH------GIQQ 126 Query: 306 SGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFV-GQWTHLALSVAGGFVALYVDCEEFQ 364 GV+ G + L G FR G+W +A+SV V + VDC++ Sbjct: 127 IGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDCKKKT 186 Query: 365 RMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHC 416 PL RS R + G +F + D + F+G I + + DP+ + +C Sbjct: 187 TKPLDRSERAIVDTNGITVFGTRI--LDEEVFEGDIQQFLITGDPKAAYDYC 236 Score = 35.0 bits (79), Expect = 0.55 Identities = 28/106 (26%), Positives = 36/106 (33%), Gaps = 17/106 (16%) Query: 148 PVGPLALAGPSSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWAPLTG 207 P GP+ GP P G G+P PG P P + P P TG Sbjct: 935 PQGPVGFPGPKGPPGPPGKD-----GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGP-TG 988 Query: 208 PSVP-----------PPSSERISEEVGLLQLLGDPPPQQVTQTDDP 242 + P PP + + G GDP PQ ++ D P Sbjct: 989 ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGP 1034 Score = 31.2 bits (69), Expect = 8.0 Identities = 28/96 (29%), Positives = 39/96 (40%), Gaps = 14/96 (14%) Query: 150 GPLALAGPSSTPQENGTTLWPSRGIPSSPGAHTTEA-GTLPAPT-----PSPPSLGRPWA 203 G + L GP E G RG+P + G+ + G +P P P PP L P Sbjct: 1468 GLIGLIGPPGEQGEKG-----DRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQG 1522 Query: 204 PLTGPSVPPPSSERISEEVGLLQLLGDP-PPQQVTQ 238 P P+ ++ + GL G P PP +V Q Sbjct: 1523 PKGNKGSTGPAGQK--GDSGLPGPPGSPGPPGEVIQ 1556 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 533 bits (1374), Expect = e-151 Identities = 395/1022 (38%), Positives = 445/1022 (43%), Gaps = 176/1022 (17%) Query: 421 GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 480 G S GA G+SG + G + PP T P G D Sbjct: 506 GPGSSGAKGESG------------DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPG 553 Query: 481 EQTTVASLGAQTLPG--SDSVSTWDGSVRTPGGRVKEGGLKGQKGE------PGVPGPPG 532 E G LPG D + + P G + G++G+ GE PG GP G Sbjct: 554 EPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG 613 Query: 533 RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE 592 GP G+P PG PG+ P GP G GPQG PGPPG+ G PG G PG G Sbjct: 614 LLGPRGTPGAPGQPGMAGVDGPPGPKGNM-----GPQGEPGPPGQQGNPGPQGLPGPQGP 668 Query: 593 DGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDK 645 G PG+ GPQG PG G G G G PG G GPPGPQGP G PGP Sbjct: 669 IGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 728 Query: 646 LTFIDMEGS----------GFGGDLEALR--------GPRGFPGPPGPPGVPGLPGEPGR 687 ++GS GF GD+ GPRG GP GP G G G+PG Sbjct: 729 DGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 788 Query: 688 FG-VNSSDVPGPAGLPGVPGREGP------PGFPG---------LPGPPGPPGREGPPGR 731 G G GLPG PGR+GP PGFPG + G PGP G+ GP G Sbjct: 789 SGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGP 848 Query: 732 TGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGL 787 G +G+ G G PG KG+ G GP G GE G G GP G PGP GPPGPPG PG Sbjct: 849 RGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGH 908 Query: 788 PA-----GFDDMEGSGGPFWSTARSADGPQGPPGLPGL---KGDPGVPGLPGAKGEVGAD 839 P GF G GP GPQGP G G +G PG PG PG +G GA Sbjct: 909 PGQRGETGFQGKTGPPGP-----GGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 963 Query: 840 GVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQ 898 G G G PG +GI+G GP G RG GE+G PG G G G GP GPPGPV E+ Sbjct: 964 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1023 Query: 899 DGSVLSVP-GPEGRPGFAGFPGPAGPKGNLGSKGERGS------------PGPKGEKGEP 945 + + P G GRPG G PGPAG KG G KG +G PGP G G P Sbjct: 1024 GSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSP 1083 Query: 946 GSIFSPDGGALG-PAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG 1004 G D G +G P QKG+KG+ G GPPGP G G G G G G PG G +G G Sbjct: 1084 GE--DGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFG 1141 Query: 1005 EPGDASLGFGMRGMPGPPGP---PGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGP 1061 + GD G RG PGPPGP G PGPPG + +V GPPG PG +GP GP Sbjct: 1142 QKGDE----GARGFPGPPGPIGLQGLPGPPGEKGENGDV----GPMGPPGPPGPRGPQGP 1193 Query: 1062 KGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFG------- 1114 GA G GPPG G GEKG+ G+AG G GE G GG G Sbjct: 1194 NGADGPQGPPGSVGS---------VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGE 1244 Query: 1115 SSLPGPPGPPGPRGYPGIPGPKGE----SIRGQPGPPGPQGPPGI----GYEGRQGPPGP 1166 + PG GPPG +G PG GPKG G PGPPG GP G G +G G PG Sbjct: 1245 AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1304 Query: 1167 PGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEV--- 1223 PGPPGP GPPGPPG GPPG GA RQ G E Sbjct: 1305 PGPPGPSG----------EAGPPGPPGKRGPPGAAGAEG-------RQGEKGAKGEAGAE 1347 Query: 1224 -PEGWLIFVAEQEELYVRVQNGFRKVQ---LEARTPLPRGTDNEVAALQPPVVQLHDSNP 1279 P G V Q G R + E P G D + PP + +P Sbjct: 1348 GPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP 1407 Query: 1280 YPRREHPHPTARPWRADDILASPP---------RLPEPQPYPGAPHHSSYVHLRPARPTS 1330 + E HP L PP LP Q PGA PA P Sbjct: 1408 GSKGEKGHPGLIG------LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIP--GPAGPLG 1459 Query: 1331 PP 1332 PP Sbjct: 1460 PP 1461 Score = 528 bits (1359), Expect = e-149 Identities = 340/784 (43%), Positives = 380/784 (48%), Gaps = 113/784 (14%) Query: 485 VASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPG 544 V +G + G + G PG + G KG+ G PG+PG PGR GP GS PG Sbjct: 762 VGQIGPRGEDGPEGPKGRAGPTGDPGPS-GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPG 820 Query: 545 PPGL------------PCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE 592 PG P P GP GP + G +GP G PG GT G DG PG PGE Sbjct: 821 FPGANGEKGARGVAGKPGPRGQRGPTGP--RGSRGARGPTGKPGPKGTSGGDGPPGPPGE 878 Query: 593 DGKPGDTGPQGFPGTPGDVGPKGDKGDPG-VGERGPPGPQGPPGPPGPSFRHDKLTFIDM 651 G G GP GFPG G GP G G PG G+RG G QG GPPGP + Sbjct: 879 RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG------GVVGP 932 Query: 652 EG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP-------GPAGLPG 703 +G +G G + G RG PGPPGPPG GLPG G+ G P GPAGL G Sbjct: 933 QGPTGETGPI----GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG 988 Query: 704 VPGREGPPGFPGLPG------PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAG 757 PG G PG G PG P GPPG G PG G G+ G G PG G +G PGPAG Sbjct: 989 FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG 1048 Query: 758 ARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGG----PFWSTARSADGPQG 813 +G G G GPAG G GP G PGP PAG +G G P ++ G G Sbjct: 1049 EKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1108 Query: 814 PPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPG 873 PPG PGL+G G PG+ G GE G G G G G EG G GP G G +G G PG Sbjct: 1109 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1168 Query: 874 KDG----VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKG---- 925 + G VG G PGPPGP GP +G+ GP+G PG G G G KG Sbjct: 1169 EKGENGDVGPMGPPGPPGPRGP----QGPNGA----DGPQGPPGSVGSVGGVGEKGEPGE 1220 Query: 926 --NLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKG 983 N G GE G GPKGE+GE G P GA GP GAKG PG GP G G G+ G Sbjct: 1221 AGNPGPPGEAGVGGPKGERGEKGEAGPP--GAAGPP--GAKGPPGDDGPKGNPGPVGFPG 1276 Query: 984 EIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAE 1043 + G PG PG G +G+ G+KGE GD G PGPPGP G GPPG P Sbjct: 1277 DPGPPGEPGPAGQDGVGGDKGEDGDP-------GQPGPPGPSGEAGPPGPP--------- 1320 Query: 1044 SSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGE 1103 + GPPG G +G G KGAKGE G GPPG+ Q A G +G RG G GE Sbjct: 1321 -GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGE 1379 Query: 1104 RGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGES----------------IRGQPGPP 1147 +G PG G G PGP GPPG G G PG KGE +G G P Sbjct: 1380 QGLPGAAGQDGP--PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1437 Query: 1148 GPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPH--RQTISVPGP---------PGPPGPP 1195 G QG PG G G GP GP GPPGPP PGP + GP PGPPG P Sbjct: 1438 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP 1497 Query: 1196 GPPG 1199 GPPG Sbjct: 1498 GPPG 1501 Score = 496 bits (1277), Expect = e-140 Identities = 339/846 (40%), Positives = 385/846 (45%), Gaps = 187/846 (22%) Query: 509 PGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPL----------GPA 558 P G G G +G G PG PG GPPG P LPG GLP P + G Sbjct: 407 PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 466 Query: 559 GP------------------ALQTVPGPQ------GPPGPPGRDGTPGRDGEP------- 587 GP AL+ PGP GP G PG G G G+P Sbjct: 467 GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 526 Query: 588 --------GDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV----GERGPPGPQGPPG 635 G PG+ G+PG G +G PG PG G +G G PG+ G RG GPQGPPG Sbjct: 527 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 586 Query: 636 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 695 PPG + I G L GPRG PG PG PG+ G+ G PG G Sbjct: 587 PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKG-----N 641 Query: 696 PGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGP 755 GP G PG PG++G PG GLPGP GP GPPG G +G G AG PG G G PG Sbjct: 642 MGPQGEPGPPGQQGNPGPQGLPGPQGP---IGPPGEKGPQGKPGLAGLPGADGPPGHPGK 698 Query: 756 AGARGESGLAGAPGPAGPPGPPGPPGPPG----------------PGLPAGFDDM--EGS 797 G GE G G PGP GP G PGP G G G P DM +G Sbjct: 699 EGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGD 758 Query: 798 GGPFWSTA-RSADGPQGPPGLPGLKGD---------------PGVPGLPGAKGEVGADGV 841 G R DGP+GP G G GD PG+PG PG +G G+ G Sbjct: 759 RGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 818 Query: 842 PGFPGL------------PGREGIAGPQGPKGDRGSRGEKGDPGKDGV-------GQPGL 882 PGFPG PG G GP GP+G RG+RG G PG G G PG Sbjct: 819 PGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGE 878 Query: 883 PGPPGPPGPVVYVSE--------QDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERG 934 GP GP GPV + +DG + PG G GF G GP GP G +G +G G Sbjct: 879 RGPQGPQGPVGFPGPKGPPGPPGKDG-LPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTG 937 Query: 935 SPGPKGEKGEPGSIFSP-DGGALGPAQK-GAKGEP---GFRGPPGPYGRPGYKGEIGFPG 989 GP GE+G PG P + G G A K GAKG+P G G GP G G+ GE G PG Sbjct: 938 ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 997 Query: 990 RPGRPGMNGLKGEKGEPGD-------ASLG-FGMRGMPGPPGPPGPPGPPGTPVYDSNVF 1041 G PG+ G +G +G PG S G G G+PG PGP GPPGP G Sbjct: 998 AQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG--------- 1048 Query: 1042 AESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQK 1101 G PG G QGP G G +G VG PGP G A GE GD+G+ G+ Sbjct: 1049 ----EKGAPGEKGPQGPAGRDGVQGPVGLPGPAG---------PAGSPGEDGDKGEIGEP 1095 Query: 1102 GERGEPGGGGFFGSSLPGPPGPPGPRGYPGI------PGPKG----------ESIRGQPG 1145 G++G G G G PGPPG GP G PGI PGP+G E RG PG Sbjct: 1096 GQKGSKGDKGENGP--PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1153 Query: 1146 PPGP---QGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTM 1201 PPGP QG PG G +G G GP GPPGPP GP GP G GP GPPG++ Sbjct: 1154 PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ-------GPNGADGPQGPPGSV 1206 Query: 1202 GASSGV 1207 G+ GV Sbjct: 1207 GSVGGV 1212 Score = 461 bits (1185), Expect = e-129 Identities = 401/1208 (33%), Positives = 498/1208 (41%), Gaps = 217/1208 (17%) Query: 247 AYVFGPDANSGQVARYHFPS-LFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKL 305 AY A + FP F DFS+LF ++P L +I + G++ Sbjct: 73 AYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYNEH------GIQQ 126 Query: 306 SGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFV-GQWTHLALSVAGGFVALYVDCEEFQ 364 GV+ G + L G FR G+W +A+SV V + VDC++ Sbjct: 127 IGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDCKKKT 186 Query: 365 RMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDS 424 PL RS R + G +F + D + F+G I + + DP+ + +C + D Sbjct: 187 TKPLDRSERAIVDTNGITVFGTRI--LDEEVFEGDIQQFLITGDPKAAYDYC-EHYSPDC 243 Query: 425 DGASG----------DSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDS 474 D ++ D + + D +E G + AP V+ + E + Sbjct: 244 DSSAPKAAQAQEPQIDEANIVDDFQEY---NYGTMESYQTEAPRHVS-------GTNEPN 293 Query: 475 RSEEV--EEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPG 532 EE+ EE T +Q D++ + GR + + G GE Sbjct: 294 PVEEIFTEEYLTGEDYDSQRKNSEDTLY----ENKEIDGRDSDLLVDGDLGEYDFYEYKE 349 Query: 533 RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE 592 P SP P GP PA + + + G G+ G+ Sbjct: 350 YEDKPTSP----------PNEEFGPGVPAETDIT-----------ETSINGHGAYGEKGQ 388 Query: 593 DGKPGDTGPQGF-PGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDM 651 G+P P G PG GP G G PG+ GP GPPG PG Sbjct: 389 KGEPAVVEPGMLVEGPPGPAGPAGIMGPPGL-----QGPTGPPGDPGD------------ 431 Query: 652 EGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGE----PGRFGVNSSDVP----------- 696 RGP G PG PG G+PG PG P R+G + S P Sbjct: 432 ------------RGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQA 479 Query: 697 ----------GPAGLPGVPGREGPPGFPGL---------PGPPGPPGREGPPGRTGQKGS 737 GP G G+ GR GP G PG PGP GP G +GPPG TG+ G Sbjct: 480 ILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGK 539 Query: 738 LGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGS 797 G GA G +G G PG G RG GL G PG G G GP GPPG P G D M G Sbjct: 540 RGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG---PPGDDGMRGE 596 Query: 798 GG-------PFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGL--- 847 G P + R GP+G PG PG G GV G PG KG +G G PG PG Sbjct: 597 DGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGN 656 Query: 848 PGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPG 907 PG +G+ GPQGP G G +G +G PG G+ PG GPPG PG E+ L PG Sbjct: 657 PGPQGLPGPQGPIGPPGEKGPQGKPGLAGL--PGADGPPGHPGKEGQSGEK--GALGPPG 712 Query: 908 PEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGP----AQKGA 963 P+G G+PGP G KG G +G +GS G KGE G PG F D G G Q G Sbjct: 713 PQGP---IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG--FKGDMGLKGDRGEVGQIGP 767 Query: 964 KGEPGFRGP---------PGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPG--DASLG 1012 +GE G GP PGP G+ G KG++G PG PG PG G KG G PG A+ Sbjct: 768 RGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGE 827 Query: 1013 FGMRGMPGPPGPPGPPGPPGT--------PVYDSNVFAESSRPGPPGLPGNQGPPGPKGA 1064 G RG+ G PGP G GP G P S GPPG PG +GP GP+G Sbjct: 828 KGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP 887 Query: 1065 KGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFG---------- 1114 G GP GPPG D L G G RG+ G +G+ G PG GG G Sbjct: 888 VGFPGPKGPPGPPGKDGL------PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGP 941 Query: 1115 ---SSLPGPPGPPGPRGYPGI---------PGPKGES-------IRGQPGP---PGPQGP 1152 PGPPGPPG +G PG PGP+G S +RG PG PG QG Sbjct: 942 IGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA 1001 Query: 1153 PGI-GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGA--SSGVRL 1209 PG+ G EG QGPPGP G PG G I +PG PGP GPPGP G GA G + Sbjct: 1002 PGLKGGEGPQGPPGPVGSPGERGSAGT-AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQG 1060 Query: 1210 WATRQAMLGQV----HEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVA 1265 A R + G V P G ++ E+ Q G + + E P P G V Sbjct: 1061 PAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG 1120 Query: 1266 ALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAP-HHSSYVHLR 1324 A P + D P PR + + PP Q PG P + Sbjct: 1121 A---PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVG 1177 Query: 1325 PARPTSPP 1332 P P PP Sbjct: 1178 PMGPPGPP 1185 Score = 362 bits (929), Expect = 2e-99 Identities = 236/553 (42%), Positives = 260/553 (47%), Gaps = 103/553 (18%) Query: 489 GAQTLPGSDSVSTWDGSVRT---PGGRVKEG-----GLKGQKGEPGVPGPPGRAGPPGSP 540 GA+ PG +S DG PG R G GLKG +G G PGP G G GS Sbjct: 967 GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA 1026 Query: 541 CLPGPPGLPCPVSPLGPAGPALQT-VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT 599 GP GLP P GP GPA + PG +GP GP GRDG G G PG G G PG+ Sbjct: 1027 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGED 1086 Query: 600 GPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS-GFGG 658 G +G G PG G KGDKG+ G GPPG QGP G PG + + +G G G Sbjct: 1087 GDKGEIGEPGQKGSKGDKGENG--PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKG 1144 Query: 659 DLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPG 718 D G RGFPGPPGP G+ GLPG PG G N DV GP G PG PG GP G G G Sbjct: 1145 D----EGARGFPGPPGPIGLQGLPGPPGEKGENG-DV-GPMGPPGPPGPRGPQGPNGADG 1198 Query: 719 PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPG 778 P GPPG G G G+KG GEAG PG G G GP G RGE G AG PG AGPPG G Sbjct: 1199 PQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG 1258 Query: 779 PPG------------------PPGPGLPAGFDDMEGS----GGPFWSTARSADGPQGPPG 816 PPG PPG PAG D + G G P G GPPG Sbjct: 1259 PPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG 1318 Query: 817 LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGP----------------- 859 PG +G PG G G +GE GA G G G PG+ G GPQGP Sbjct: 1319 PPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG 1378 Query: 860 -------------------------KGDRGSRGEKGDPGKDGV----------GQPGLPG 884 KGD GS+GEKG PG G+ G GLPG Sbjct: 1379 EQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1438 Query: 885 PPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGS------KGERGSPGP 938 G PG ++ DG + GP G PG G PGP GPKGN GS KG+ G PGP Sbjct: 1439 TQGSPG-----AKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP 1493 Query: 939 KGEKGEPGSIFSP 951 G G PG + P Sbjct: 1494 PGSPGPPGEVIQP 1506 Score = 347 bits (891), Expect = 4e-95 Identities = 226/509 (44%), Positives = 251/509 (49%), Gaps = 84/509 (16%) Query: 459 PVTTPPLAG--GSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPG------ 510 PV P AG GS ED E+ E S G + G G V PG Sbjct: 1070 PVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1129 Query: 511 --GRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP---VSPLGPAGPALQTV 565 G + G+ GQKG+ G G PG GP G LPGPPG V P+GP GP Sbjct: 1130 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP----- 1184 Query: 566 PGPQGPPGPPGRDGT---PGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV 622 PGP+GP GP G DG PG G G GE G+PG+ G G PG G GPKG++G+ G Sbjct: 1185 PGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG- 1243 Query: 623 GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLP 682 E GPPG GPPG GP G D GP+G PGP G PG PG P Sbjct: 1244 -EAGPPGAAGPPGAKGPP----------------GDD-----GPKGNPGPVGFPGDPGPP 1281 Query: 683 GEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAG 742 GEPG PAG GV G +G G PG PGPPGP G GPPG G++G G AG Sbjct: 1282 GEPG-----------PAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAG 1330 Query: 743 APGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFW 802 A G +G KGA G AGA G G G GP GP G PGP G G P G + G+ G Sbjct: 1331 AEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAG--- 1387 Query: 803 STARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGD 862 GP GPPGLPGLKGD PG+KGE G PGL G G G QG KGD Sbjct: 1388 --QDGPPGPMGPPGLPGLKGD------PGSKGE------KGHPGLIGLIGPPGEQGEKGD 1433 Query: 863 RGSRGEKGDPGKDGVGQ-PGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPA 921 RG G +G PG G G PG GP GPPGP +PGP+G G G GPA Sbjct: 1434 RGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP-----------GLPGPQGPKGNKGSTGPA 1482 Query: 922 GPKGNLGSKGERGSPGPKGEKGEPGSIFS 950 G KG+ G G GSPGP GE +P I S Sbjct: 1483 GQKGDSGLPGPPGSPGPPGEVIQPLPILS 1511 Score = 35.0 bits (79), Expect = 0.55 Identities = 28/106 (26%), Positives = 36/106 (33%), Gaps = 17/106 (16%) Query: 148 PVGPLALAGPSSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWAPLTG 207 P GP+ GP P G G+P PG P P + P P TG Sbjct: 884 PQGPVGFPGPKGPPGPPGKD-----GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGP-TG 937 Query: 208 PSVP-----------PPSSERISEEVGLLQLLGDPPPQQVTQTDDP 242 + P PP + + G GDP PQ ++ D P Sbjct: 938 ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGP 983 Score = 31.2 bits (69), Expect = 8.0 Identities = 28/96 (29%), Positives = 39/96 (40%), Gaps = 14/96 (14%) Query: 150 GPLALAGPSSTPQENGTTLWPSRGIPSSPGAHTTEA-GTLPAPT-----PSPPSLGRPWA 203 G + L GP E G RG+P + G+ + G +P P P PP L P Sbjct: 1417 GLIGLIGPPGEQGEKG-----DRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQG 1471 Query: 204 PLTGPSVPPPSSERISEEVGLLQLLGDP-PPQQVTQ 238 P P+ ++ + GL G P PP +V Q Sbjct: 1472 PKGNKGSTGPAGQK--GDSGLPGPPGSPGPPGEVIQ 1505 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 533 bits (1374), Expect = e-151 Identities = 395/1022 (38%), Positives = 445/1022 (43%), Gaps = 176/1022 (17%) Query: 421 GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 480 G S GA G+SG + G + PP T P G D Sbjct: 545 GPGSSGAKGESG------------DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPG 592 Query: 481 EQTTVASLGAQTLPG--SDSVSTWDGSVRTPGGRVKEGGLKGQKGE------PGVPGPPG 532 E G LPG D + + P G + G++G+ GE PG GP G Sbjct: 593 EPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG 652 Query: 533 RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE 592 GP G+P PG PG+ P GP G GPQG PGPPG+ G PG G PG G Sbjct: 653 LLGPRGTPGAPGQPGMAGVDGPPGPKGNM-----GPQGEPGPPGQQGNPGPQGLPGPQGP 707 Query: 593 DGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDK 645 G PG+ GPQG PG G G G G PG G GPPGPQGP G PGP Sbjct: 708 IGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 767 Query: 646 LTFIDMEGS----------GFGGDLEALR--------GPRGFPGPPGPPGVPGLPGEPGR 687 ++GS GF GD+ GPRG GP GP G G G+PG Sbjct: 768 DGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 827 Query: 688 FG-VNSSDVPGPAGLPGVPGREGP------PGFPG---------LPGPPGPPGREGPPGR 731 G G GLPG PGR+GP PGFPG + G PGP G+ GP G Sbjct: 828 SGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGP 887 Query: 732 TGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGL 787 G +G+ G G PG KG+ G GP G GE G G GP G PGP GPPGPPG PG Sbjct: 888 RGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGH 947 Query: 788 PA-----GFDDMEGSGGPFWSTARSADGPQGPPGLPGL---KGDPGVPGLPGAKGEVGAD 839 P GF G GP GPQGP G G +G PG PG PG +G GA Sbjct: 948 PGQRGETGFQGKTGPPGP-----GGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 1002 Query: 840 GVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQ 898 G G G PG +GI+G GP G RG GE+G PG G G G GP GPPGPV E+ Sbjct: 1003 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1062 Query: 899 DGSVLSVP-GPEGRPGFAGFPGPAGPKGNLGSKGERGS------------PGPKGEKGEP 945 + + P G GRPG G PGPAG KG G KG +G PGP G G P Sbjct: 1063 GSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSP 1122 Query: 946 GSIFSPDGGALG-PAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG 1004 G D G +G P QKG+KG+ G GPPGP G G G G G G PG G +G G Sbjct: 1123 GE--DGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFG 1180 Query: 1005 EPGDASLGFGMRGMPGPPGP---PGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGP 1061 + GD G RG PGPPGP G PGPPG + +V GPPG PG +GP GP Sbjct: 1181 QKGDE----GARGFPGPPGPIGLQGLPGPPGEKGENGDV----GPMGPPGPPGPRGPQGP 1232 Query: 1062 KGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFG------- 1114 GA G GPPG G GEKG+ G+AG G GE G GG G Sbjct: 1233 NGADGPQGPPGSVGS---------VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGE 1283 Query: 1115 SSLPGPPGPPGPRGYPGIPGPKGE----SIRGQPGPPGPQGPPGI----GYEGRQGPPGP 1166 + PG GPPG +G PG GPKG G PGPPG GP G G +G G PG Sbjct: 1284 AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1343 Query: 1167 PGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEV--- 1223 PGPPGP GPPGPPG GPPG GA RQ G E Sbjct: 1344 PGPPGPSG----------EAGPPGPPGKRGPPGAAGAEG-------RQGEKGAKGEAGAE 1386 Query: 1224 -PEGWLIFVAEQEELYVRVQNGFRKVQ---LEARTPLPRGTDNEVAALQPPVVQLHDSNP 1279 P G V Q G R + E P G D + PP + +P Sbjct: 1387 GPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP 1446 Query: 1280 YPRREHPHPTARPWRADDILASPP---------RLPEPQPYPGAPHHSSYVHLRPARPTS 1330 + E HP L PP LP Q PGA PA P Sbjct: 1447 GSKGEKGHPGLIG------LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIP--GPAGPLG 1498 Query: 1331 PP 1332 PP Sbjct: 1499 PP 1500 Score = 528 bits (1359), Expect = e-149 Identities = 340/784 (43%), Positives = 380/784 (48%), Gaps = 113/784 (14%) Query: 485 VASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPG 544 V +G + G + G PG + G KG+ G PG+PG PGR GP GS PG Sbjct: 801 VGQIGPRGEDGPEGPKGRAGPTGDPGPS-GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPG 859 Query: 545 PPGL------------PCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE 592 PG P P GP GP + G +GP G PG GT G DG PG PGE Sbjct: 860 FPGANGEKGARGVAGKPGPRGQRGPTGP--RGSRGARGPTGKPGPKGTSGGDGPPGPPGE 917 Query: 593 DGKPGDTGPQGFPGTPGDVGPKGDKGDPG-VGERGPPGPQGPPGPPGPSFRHDKLTFIDM 651 G G GP GFPG G GP G G PG G+RG G QG GPPGP + Sbjct: 918 RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG------GVVGP 971 Query: 652 EG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP-------GPAGLPG 703 +G +G G + G RG PGPPGPPG GLPG G+ G P GPAGL G Sbjct: 972 QGPTGETGPI----GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG 1027 Query: 704 VPGREGPPGFPGLPG------PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAG 757 PG G PG G PG P GPPG G PG G G+ G G PG G +G PGPAG Sbjct: 1028 FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG 1087 Query: 758 ARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGG----PFWSTARSADGPQG 813 +G G G GPAG G GP G PGP PAG +G G P ++ G G Sbjct: 1088 EKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1147 Query: 814 PPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPG 873 PPG PGL+G G PG+ G GE G G G G G EG G GP G G +G G PG Sbjct: 1148 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1207 Query: 874 KDG----VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKG---- 925 + G VG G PGPPGP GP +G+ GP+G PG G G G KG Sbjct: 1208 EKGENGDVGPMGPPGPPGPRGP----QGPNGA----DGPQGPPGSVGSVGGVGEKGEPGE 1259 Query: 926 --NLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKG 983 N G GE G GPKGE+GE G P GA GP GAKG PG GP G G G+ G Sbjct: 1260 AGNPGPPGEAGVGGPKGERGEKGEAGPP--GAAGPP--GAKGPPGDDGPKGNPGPVGFPG 1315 Query: 984 EIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAE 1043 + G PG PG G +G+ G+KGE GD G PGPPGP G GPPG P Sbjct: 1316 DPGPPGEPGPAGQDGVGGDKGEDGDP-------GQPGPPGPSGEAGPPGPP--------- 1359 Query: 1044 SSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGE 1103 + GPPG G +G G KGAKGE G GPPG+ Q A G +G RG G GE Sbjct: 1360 -GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGE 1418 Query: 1104 RGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGES----------------IRGQPGPP 1147 +G PG G G PGP GPPG G G PG KGE +G G P Sbjct: 1419 QGLPGAAGQDGP--PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1476 Query: 1148 GPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPH--RQTISVPGP---------PGPPGPP 1195 G QG PG G G GP GP GPPGPP PGP + GP PGPPG P Sbjct: 1477 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP 1536 Query: 1196 GPPG 1199 GPPG Sbjct: 1537 GPPG 1540 Score = 496 bits (1277), Expect = e-140 Identities = 339/846 (40%), Positives = 385/846 (45%), Gaps = 187/846 (22%) Query: 509 PGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPL----------GPA 558 P G G G +G G PG PG GPPG P LPG GLP P + G Sbjct: 446 PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 505 Query: 559 GP------------------ALQTVPGPQ------GPPGPPGRDGTPGRDGEP------- 587 GP AL+ PGP GP G PG G G G+P Sbjct: 506 GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 565 Query: 588 --------GDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV----GERGPPGPQGPPG 635 G PG+ G+PG G +G PG PG G +G G PG+ G RG GPQGPPG Sbjct: 566 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 625 Query: 636 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 695 PPG + I G L GPRG PG PG PG+ G+ G PG G Sbjct: 626 PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKG-----N 680 Query: 696 PGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGP 755 GP G PG PG++G PG GLPGP GP GPPG G +G G AG PG G G PG Sbjct: 681 MGPQGEPGPPGQQGNPGPQGLPGPQGP---IGPPGEKGPQGKPGLAGLPGADGPPGHPGK 737 Query: 756 AGARGESGLAGAPGPAGPPGPPGPPGPPG----------------PGLPAGFDDM--EGS 797 G GE G G PGP GP G PGP G G G P DM +G Sbjct: 738 EGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGD 797 Query: 798 GGPFWSTA-RSADGPQGPPGLPGLKGD---------------PGVPGLPGAKGEVGADGV 841 G R DGP+GP G G GD PG+PG PG +G G+ G Sbjct: 798 RGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 857 Query: 842 PGFPGL------------PGREGIAGPQGPKGDRGSRGEKGDPGKDGV-------GQPGL 882 PGFPG PG G GP GP+G RG+RG G PG G G PG Sbjct: 858 PGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGE 917 Query: 883 PGPPGPPGPVVYVSE--------QDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERG 934 GP GP GPV + +DG + PG G GF G GP GP G +G +G G Sbjct: 918 RGPQGPQGPVGFPGPKGPPGPPGKDG-LPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTG 976 Query: 935 SPGPKGEKGEPGSIFSP-DGGALGPAQK-GAKGEP---GFRGPPGPYGRPGYKGEIGFPG 989 GP GE+G PG P + G G A K GAKG+P G G GP G G+ GE G PG Sbjct: 977 ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 1036 Query: 990 RPGRPGMNGLKGEKGEPGD-------ASLG-FGMRGMPGPPGPPGPPGPPGTPVYDSNVF 1041 G PG+ G +G +G PG S G G G+PG PGP GPPGP G Sbjct: 1037 AQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG--------- 1087 Query: 1042 AESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQK 1101 G PG G QGP G G +G VG PGP G A GE GD+G+ G+ Sbjct: 1088 ----EKGAPGEKGPQGPAGRDGVQGPVGLPGPAG---------PAGSPGEDGDKGEIGEP 1134 Query: 1102 GERGEPGGGGFFGSSLPGPPGPPGPRGYPGI------PGPKG----------ESIRGQPG 1145 G++G G G G PGPPG GP G PGI PGP+G E RG PG Sbjct: 1135 GQKGSKGDKGENGP--PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1192 Query: 1146 PPGP---QGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTM 1201 PPGP QG PG G +G G GP GPPGPP GP GP G GP GPPG++ Sbjct: 1193 PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ-------GPNGADGPQGPPGSV 1245 Query: 1202 GASSGV 1207 G+ GV Sbjct: 1246 GSVGGV 1251 Score = 457 bits (1177), Expect = e-128 Identities = 399/1213 (32%), Positives = 498/1213 (41%), Gaps = 188/1213 (15%) Query: 247 AYVFGPDANSGQVARYHFPS-LFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKL 305 AY A + FP F DFS+LF ++P L +I + G++ Sbjct: 73 AYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYNEH------GIQQ 126 Query: 306 SGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFV-GQWTHLALSVAGGFVALYVDCEEFQ 364 GV+ G + L G FR G+W +A+SV V + VDC++ Sbjct: 127 IGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDCKKKT 186 Query: 365 RMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDS 424 PL RS R + G +F + D + F+G I + + DP+ + +C + D Sbjct: 187 TKPLDRSERAIVDTNGITVFGTRI--LDEEVFEGDIQQFLITGDPKAAYDYC-EHYSPDC 243 Query: 425 DGASGDSGSG-------------------LGDAR----------ELLREETGAALKPRL- 454 D ++ + G+A + EET A + + Sbjct: 244 DSSAPKAAQAQEPQIDEYAPEDIIEYDYEYGEAEYKEAESVTEGPTVTEETIAQTEANIV 303 Query: 455 ---------PAPPPVTTPPLAGGSSTEDSRSEEV--EEQTTVASLGAQ------TLPGSD 497 T P + E + EE+ EE T +Q TL + Sbjct: 304 DDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGEDYDSQRKNSEDTLYENK 363 Query: 498 SVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGP 557 + D + G + + ++ E PP PG P ++ Sbjct: 364 EIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPA-------ETDITETSI 416 Query: 558 AGPALQTVPGPQGPPG--PPGR--DGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGP 613 G G +G P PG +G PG G G G G G TGP PG PGD GP Sbjct: 417 NGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGP---PGDPGDRGP 473 Query: 614 KGDKGDPGV-GERGPPGPQ-------GPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRG 665 G G PG G GPPG G G GP+ I + + L+ R Sbjct: 474 PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPT--------ISAQEAQAQAILQQAR- 524 Query: 666 PRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGR 725 GPPGP G+ G PG G PG +G G G GP G G+ GPPGP G+ Sbjct: 525 -IALRGPPGPMGLTGRPGPVGG--------PGSSGAKGESGDPGPQGPRGVQGPPGPTGK 575 Query: 726 EGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGP 785 G GR G G G G PG KG +G G G G+ G G GP GPPGPPG G G Sbjct: 576 PGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGE 635 Query: 786 GLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFP 845 G + G GP R GP+G PG PG G GV G PG KG +G G PG P Sbjct: 636 DGEIGPRGLPGEAGP-----RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPP 690 Query: 846 GL---PGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSV 902 G PG +G+ GPQGP G G +G +G PG G+ PG GPPG PG E+ Sbjct: 691 GQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGL--PGADGPPGHPGKEGQSGEK--GA 746 Query: 903 LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGP---- 958 L PGP+G G+PGP G KG G +G +GS G KGE G PG F D G G Sbjct: 747 LGPPGPQGP---IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG--FKGDMGLKGDRGEV 801 Query: 959 AQKGAKGEPGFRGP---------PGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPG-- 1007 Q G +GE G GP PGP G+ G KG++G PG PG PG G KG G PG Sbjct: 802 GQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFP 861 Query: 1008 DASLGFGMRGMPGPPGPPGPPGPPGT--------PVYDSNVFAESSRPGPPGLPGNQGPP 1059 A+ G RG+ G PGP G GP G P S GPPG PG +GP Sbjct: 862 GANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQ 921 Query: 1060 GPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFG----- 1114 GP+G G GP GPPG D L G G RG+ G +G+ G PG GG G Sbjct: 922 GPQGPVGFPGPKGPPGPPGKDGL------PGHPGQRGETGFQGKTGPPGPGGVVGPQGPT 975 Query: 1115 --------SSLPGPPGPPGPRGYPGI---------PGPKGES-------IRGQPGP---P 1147 PGPPGPPG +G PG PGP+G S +RG PG P Sbjct: 976 GETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLP 1035 Query: 1148 GPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGA--S 1204 G QG PG+ G EG QGPPGP G PG G I +PG PGP GPPGP G GA Sbjct: 1036 GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGT-AGPIGLPGRPGPQGPPGPAGEKGAPGE 1094 Query: 1205 SGVRLWATRQAMLGQV----HEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGT 1260 G + A R + G V P G ++ E+ Q G + + E P P G Sbjct: 1095 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1154 Query: 1261 DNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAP-HHSS 1319 V A P + D P PR + + PP Q PG P Sbjct: 1155 QGPVGA---PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGE 1211 Query: 1320 YVHLRPARPTSPP 1332 + P P PP Sbjct: 1212 NGDVGPMGPPGPP 1224 Score = 362 bits (929), Expect = 2e-99 Identities = 236/553 (42%), Positives = 260/553 (47%), Gaps = 103/553 (18%) Query: 489 GAQTLPGSDSVSTWDGSVRT---PGGRVKEG-----GLKGQKGEPGVPGPPGRAGPPGSP 540 GA+ PG +S DG PG R G GLKG +G G PGP G G GS Sbjct: 1006 GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA 1065 Query: 541 CLPGPPGLPCPVSPLGPAGPALQT-VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT 599 GP GLP P GP GPA + PG +GP GP GRDG G G PG G G PG+ Sbjct: 1066 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGED 1125 Query: 600 GPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS-GFGG 658 G +G G PG G KGDKG+ G GPPG QGP G PG + + +G G G Sbjct: 1126 GDKGEIGEPGQKGSKGDKGENG--PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKG 1183 Query: 659 DLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPG 718 D G RGFPGPPGP G+ GLPG PG G N DV GP G PG PG GP G G G Sbjct: 1184 D----EGARGFPGPPGPIGLQGLPGPPGEKGENG-DV-GPMGPPGPPGPRGPQGPNGADG 1237 Query: 719 PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPG 778 P GPPG G G G+KG GEAG PG G G GP G RGE G AG PG AGPPG G Sbjct: 1238 PQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG 1297 Query: 779 PPG------------------PPGPGLPAGFDDMEGS----GGPFWSTARSADGPQGPPG 816 PPG PPG PAG D + G G P G GPPG Sbjct: 1298 PPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG 1357 Query: 817 LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGP----------------- 859 PG +G PG G G +GE GA G G G PG+ G GPQGP Sbjct: 1358 PPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG 1417 Query: 860 -------------------------KGDRGSRGEKGDPGKDGV----------GQPGLPG 884 KGD GS+GEKG PG G+ G GLPG Sbjct: 1418 EQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1477 Query: 885 PPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGS------KGERGSPGP 938 G PG ++ DG + GP G PG G PGP GPKGN GS KG+ G PGP Sbjct: 1478 TQGSPG-----AKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP 1532 Query: 939 KGEKGEPGSIFSP 951 G G PG + P Sbjct: 1533 PGSPGPPGEVIQP 1545 Score = 347 bits (891), Expect = 4e-95 Identities = 226/509 (44%), Positives = 251/509 (49%), Gaps = 84/509 (16%) Query: 459 PVTTPPLAG--GSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPG------ 510 PV P AG GS ED E+ E S G + G G V PG Sbjct: 1109 PVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1168 Query: 511 --GRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP---VSPLGPAGPALQTV 565 G + G+ GQKG+ G G PG GP G LPGPPG V P+GP GP Sbjct: 1169 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP----- 1223 Query: 566 PGPQGPPGPPGRDGT---PGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV 622 PGP+GP GP G DG PG G G GE G+PG+ G G PG G GPKG++G+ G Sbjct: 1224 PGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG- 1282 Query: 623 GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLP 682 E GPPG GPPG GP G D GP+G PGP G PG PG P Sbjct: 1283 -EAGPPGAAGPPGAKGPP----------------GDD-----GPKGNPGPVGFPGDPGPP 1320 Query: 683 GEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAG 742 GEPG PAG GV G +G G PG PGPPGP G GPPG G++G G AG Sbjct: 1321 GEPG-----------PAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAG 1369 Query: 743 APGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFW 802 A G +G KGA G AGA G G G GP GP G PGP G G P G + G+ G Sbjct: 1370 AEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAG--- 1426 Query: 803 STARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGD 862 GP GPPGLPGLKGD PG+KGE G PGL G G G QG KGD Sbjct: 1427 --QDGPPGPMGPPGLPGLKGD------PGSKGE------KGHPGLIGLIGPPGEQGEKGD 1472 Query: 863 RGSRGEKGDPGKDGVGQ-PGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPA 921 RG G +G PG G G PG GP GPPGP +PGP+G G G GPA Sbjct: 1473 RGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP-----------GLPGPQGPKGNKGSTGPA 1521 Query: 922 GPKGNLGSKGERGSPGPKGEKGEPGSIFS 950 G KG+ G G GSPGP GE +P I S Sbjct: 1522 GQKGDSGLPGPPGSPGPPGEVIQPLPILS 1550 Score = 35.0 bits (79), Expect = 0.55 Identities = 28/106 (26%), Positives = 36/106 (33%), Gaps = 17/106 (16%) Query: 148 PVGPLALAGPSSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWAPLTG 207 P GP+ GP P G G+P PG P P + P P TG Sbjct: 923 PQGPVGFPGPKGPPGPPGKD-----GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGP-TG 976 Query: 208 PSVP-----------PPSSERISEEVGLLQLLGDPPPQQVTQTDDP 242 + P PP + + G GDP PQ ++ D P Sbjct: 977 ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGP 1022 Score = 31.2 bits (69), Expect = 8.0 Identities = 28/96 (29%), Positives = 39/96 (40%), Gaps = 14/96 (14%) Query: 150 GPLALAGPSSTPQENGTTLWPSRGIPSSPGAHTTEA-GTLPAPT-----PSPPSLGRPWA 203 G + L GP E G RG+P + G+ + G +P P P PP L P Sbjct: 1456 GLIGLIGPPGEQGEKG-----DRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQG 1510 Query: 204 PLTGPSVPPPSSERISEEVGLLQLLGDP-PPQQVTQ 238 P P+ ++ + GL G P PP +V Q Sbjct: 1511 PKGNKGSTGPAGQK--GDSGLPGPPGSPGPPGEVIQ 1544 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 530 bits (1365), Expect = e-150 Identities = 407/1117 (36%), Positives = 460/1117 (41%), Gaps = 252/1117 (22%) Query: 419 EEGDDSD-GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSE 477 E+G D G G+ G+ R+ E G P P PP PP GG+ Sbjct: 130 EQGPRGDRGDKGEKGAPGPRGRD---GEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGG 186 Query: 478 EVEEQTTVASLGAQTLP-GSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGP 536 +E+ A LG P G G PG + +G G+ GEPGV GP G GP Sbjct: 187 -FDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGN-PGEPGEPGVSGPMGPRGP 244 Query: 537 PGSPCLPGP------PGLPCPVSPLGPAG----PALQTVPGPQGPPGPPGRDGT------ 580 PG P PG PG P GP G P +PG +G G PG DG Sbjct: 245 PGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGA 304 Query: 581 PGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPS 640 PG GE G PGE+G PG GP+G PG G GP G G G G PGP GPPGP GP+ Sbjct: 305 PGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAG--ARGNDGQPGPAGPPGPVGPA 362 Query: 641 FRHDKLTFIDMEGSGFGG--------------DLEALRGPRGFPGPPGPPGVPGLPGEPG 686 G GF G E +GPRG PG PG PG G G PG Sbjct: 363 -----------GGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPG 411 Query: 687 RFGV----NSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAG 742 G+ S+ PG AG PG PG GPPG G GP GP G+ G PG G KG G G Sbjct: 412 TDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKG 471 Query: 743 APGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG------------------ 784 PG G +GAPGPAG G+ G G PG GP GPPG G PG Sbjct: 472 EPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPG 531 Query: 785 ----------------------PGLPA--GFDDMEGSGGPFW----STARSADGPQGPPG 816 PGLP G G GP S A DG GPPG Sbjct: 532 ERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPG 591 Query: 817 LPGLKGDPGVPGLPGAK---------GEVGADGVPGFPGLPGRE---GIAGPQGPKGDRG 864 G +G PGV G PG K GE G G PG GLPG++ G AGP GP G G Sbjct: 592 PQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAG 651 Query: 865 SRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPK 924 RGE+G PG G GLPGPPGPPG + G PG +G PG AG PG GP+ Sbjct: 652 ERGEQGAPGPSGF--QGLPGPPGPPG-------EGGK----PGDQGVPGEAGAPGLVGPR 698 Query: 925 GNLGSKGERGSPGPKGEKGEPGSIFSP--DG--GALGPA-QKGAKGEPGFR--------- 970 G G GERGSPG +G +G G +P DG GA GPA GA+G PG + Sbjct: 699 GERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAA 758 Query: 971 ---------------------------------GPPGPYGRPGYKGEIGFPGRPGRPGMN 997 GPPGP G G KGE+G PG G G Sbjct: 759 GIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGAR 818 Query: 998 GLKGEKGEPG-DASLGF----------------------GMRGMPGPPGPPGPPGPPGT- 1033 G GE+GE G GF G G PGP GP G PGP G Sbjct: 819 GAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPT 878 Query: 1034 -------------PVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGP------PGPP 1074 P + + R GPPG GN GPPGP G G+ GP GPP Sbjct: 879 GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP 938 Query: 1075 GQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIP 1133 G+ LQ A GEKG+ GD G G G PG G G + G PG G RG+PG+P Sbjct: 939 GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLP 998 Query: 1134 GPKGE-------SIRGQPGPPGPQGPPGI----GYEGRQGPPGPPGPPGPPSFPG----- 1177 GP GE G GPPGP GPPG+ G GR+G PG GPPG G Sbjct: 999 GPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDR 1058 Query: 1178 PHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLG----------QVHEVPEGW 1227 + PG PGPPG PGP G G G R A Q +G Q + P G Sbjct: 1059 GETGAVGAPGAPGPPGSPGPAGPTG-KQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGD 1117 Query: 1228 LIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQP-----PVVQLHDSNPYPR 1282 E E ++ GF +Q P P G P P + S Sbjct: 1118 KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGA 1177 Query: 1283 REHPHPTARPW----RADDILASPPRLPEPQPYPGAP 1315 P P P + A PP P P PG P Sbjct: 1178 NGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPP 1214 Score = 528 bits (1361), Expect = e-149 Identities = 351/888 (39%), Positives = 407/888 (45%), Gaps = 163/888 (18%) Query: 430 DSGSGLGDARELLREETGAALKPRLPAPP--PVTTPPLAGGSSTEDSRSEEVEEQTTVAS 487 D+G+ L D +++ E+ L P +P P+ LA S + ++ E Sbjct: 58 DTGTVLCD--DIICEDVKDCLSPEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDI 115 Query: 488 LGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPG 547 +G + PG P G G +G KGE G PGP GR G PG+P PGPPG Sbjct: 116 VGPKGPPGPQG----------PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPG 165 Query: 548 LPCPVSP---------------------------LGPAGPALQTVPGPQGPPGPPGRDGT 580 P P P GP GP GP+GPPGP G G Sbjct: 166 PPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM-----GPRGPPGPAGAPGP 220 Query: 581 PGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPG-VGERGPPGPQGP---PGP 636 G G PG+PGE G G GP+G PG PG G G+ G PG GERGPPGPQG PG Sbjct: 221 QGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGT 280 Query: 637 PGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFP---GPPGPPGVPGLPGEPGRFGV--- 690 PG + ++G+ ++G G P G PGP G GLPGE GR G Sbjct: 281 PGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGA 340 Query: 691 ----NSSDVPGPAGLPGVPGREGPPGFPGLPGPP---------GPPGREGPPGRTGQKGS 737 + PGPAG PG G G PGFPG PG GP G +GP G G GS Sbjct: 341 AGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGS 400 Query: 738 LGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLP------AGF 791 G AGA G+ G+ G PG G+ G G+AGAPG GP GPPGP G GP P G Sbjct: 401 PGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGI 460 Query: 792 DDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGAD---GVPGFPGLP 848 +G GP + GPQG PG G +G G G PG G +G G PG G P Sbjct: 461 AGFKGEQGPKGEPGPA--GPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFP 518 Query: 849 GREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQ-DGSVLSVPG 907 G++G+AGP+G G+RG G G G + G PG PG PG PG D G Sbjct: 519 GQDGLAGPKGAPGERGPSGLAGPKGAN--GDPGRPGEPGLPGARGLTGRPGDAGPQGKVG 576 Query: 908 PEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEP 967 P G PG G PGP GP+G G G G PGPKG GEPG GE Sbjct: 577 PSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGK----------------AGEK 620 Query: 968 GFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGP 1027 G G PG G PG GE G G PG G G +GE+G PG + G +G+PGPPGPPG Sbjct: 621 GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPS----GFQGLPGPPGPPGE 676 Query: 1028 PGPPGTPVYDSNVFAESSRP------------------------GPPGLPGNQGPPGPKG 1063 G PG D V E+ P GP GLPG G GPKG Sbjct: 677 GGKPG----DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKG 732 Query: 1064 AKGEVGPP---GPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGP 1120 A G GPP GPPG + A + G KGDRGD G+KG G PG G G L GP Sbjct: 733 ASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDG--GRGLTGP 790 Query: 1121 PGPPGP------RGYPGIPGPKGES-------IRGQPGPPGP---QGPPGI--------- 1155 GPPGP +G G PGP G + RG+ GPPGP GPPG Sbjct: 791 IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGE 850 Query: 1156 -GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1202 G G++G G PGP GP PGP T V GP G G GPPG G Sbjct: 851 QGEAGQKGDAGAPGPQGPSGAPGPQGPT-GVTGPKGARGAQGPPGATG 897 Score = 518 bits (1334), Expect = e-146 Identities = 331/766 (43%), Positives = 374/766 (48%), Gaps = 99/766 (12%) Query: 489 GAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGL 548 G + PG D ++ G PG R GL G KG G PG PG G PG+ L G PG Sbjct: 513 GNRGFPGQDGLA---GPKGAPGER-GPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGD 568 Query: 549 PCPVSPLGPAG-PALQTVPGPQGP------------PGPPGRDGTPGRDGE---PGDPGE 592 P +GP+G P PGP GP PGP G +G PG+ GE PG PG Sbjct: 569 AGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL 628 Query: 593 DGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDME 652 G PG G G G PG GP G++G+ G GP G QG PGPPGP K + Sbjct: 629 RGLPGKDGETGAAGPPGPAGPAGERGEQGAP--GPSGFQGLPGPPGPPGEGGKPGDQGVP 686 Query: 653 GSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP-GPAGLPGVPGREGPP 711 G L RG RGFPG G PG GL G G G +D P G +G G PG +GPP Sbjct: 687 GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPP 746 Query: 712 GFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA------PGPAGARGESGLA 765 G G+PG G G GP G G G G GAPG G +G PGPAGA GE G Sbjct: 747 GLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEV 806 Query: 766 GAPGPAGPPGP---------PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSAD----GPQ 812 G PGPAG G GPPGP G P G D G+ G + D GPQ Sbjct: 807 GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 866 Query: 813 GPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGR---------EGIAGPQGPKGDR 863 GP G PG +G GV G GA+G G G GFPG GR G GP GP G Sbjct: 867 GPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKD 926 Query: 864 GSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAG 922 G +G +GD G G G+PGL GP GPPG G G G +G GP G Sbjct: 927 GPKGARGDSGPPGRAGEPGLQGPAGPPGE--------------KGEPGDDGPSGAEGPPG 972 Query: 923 PKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYK 982 P+G G +G G PG +GE+G PG + P G P ++GA G G RGPPGP G PG Sbjct: 973 PQGLAGQRGIVGLPGQRGERGFPG-LPGPSGE---PGKQGAPGASGDRGPPGPVGPPGLT 1028 Query: 983 GEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFA 1042 G G PGR G PG +G G G G G RG G G PG PGPPG+P Sbjct: 1029 GPAGEPGREGSPGADGPPGRDGAAGVK----GDRGETGAVGAPGAPGPPGSP-------- 1076 Query: 1043 ESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKG 1102 GP G G QG G GA+G +GP GP G Q G +GD+G+AG+ G Sbjct: 1077 -----GPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQ------GPRGDKGEAGEPG 1125 Query: 1103 ERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI-GYEGRQ 1161 ERG G GF G L G PGPPGP G G GP G S G GPPGP GP G G G Sbjct: 1126 ERGLKGHRGFTG--LQGLPGPPGPSGDQGASGPAGPS--GPRGPPGPVGPSGKDGANGIP 1181 Query: 1162 GPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGV 1207 GP GPPGP G GP + PGPPGPPGPPGP M A +G+ Sbjct: 1182 GPIGPPGPRGRSGETGPAGPPGN-PGPPGPPGPPGPGIDMSAFAGL 1226 Score = 404 bits (1037), Expect = e-112 Identities = 280/742 (37%), Positives = 332/742 (44%), Gaps = 114/742 (15%) Query: 426 GASGDSGS----GLGDARELLREE-----------TGAALKPRLPAPPPVT----TPPLA 466 GA+GD G GL AR L +GA + P PP P + Sbjct: 543 GANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVM 602 Query: 467 GGSSTEDSRSE--EVEEQTTVASLGAQTLPGSDS---VSTWDGSVRTPGGRVKEG--GLK 519 G + + E + E+ + G + LPG D + G G R ++G G Sbjct: 603 GFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPS 662 Query: 520 GQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG-PALQTVPGPQGPPGPPGRD 578 G +G PG PGPPG G PG +PG G P V P G G P + PG QG GP G Sbjct: 663 GFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP 722 Query: 579 GTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGD------VGPKGDKGDPGVGERGPPGPQG 632 GTPG DG G G G PG GP G G PG+ GPKGD+GD VGE+GP G G Sbjct: 723 GTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD--VGEKGPEGAPG 780 Query: 633 ---------PPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPG 683 P GPPGP+ + + + G G RG GPPGP G G PG Sbjct: 781 KDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPG 840 Query: 684 EPGRFGVNSSD----------VPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTG 733 G+ G PGP G G PG +GP G + GP G G +GPPG TG Sbjct: 841 ADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTG---VTGPKGARGAQGPPGATG 897 Query: 734 QKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDD 793 G+ G G PG G+ G PGP G G+ G GA G +GPPG G PG GP P G Sbjct: 898 FPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG 957 Query: 794 MEGSGGPFWSTARSADGPQGPPG------LPGLKGDPGVPGLPGAKGEVGADGVPGF--- 844 G GP S A GPQG G LPG +G+ G PGLPG GE G G PG Sbjct: 958 EPGDDGP--SGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGD 1015 Query: 845 ---------PGL------PGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGP 888 PGL PGREG G GP G G+ G KGD G+ G VG PG PGPPG Sbjct: 1016 RGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS 1075 Query: 889 PGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSI 948 PGP G +G G AG GP GP G G++G +G GP+G+KGE G Sbjct: 1076 PGPA-----------GPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGE- 1123 Query: 949 FSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGD 1008 P ++G KG GF G G G PG G+ G G G G G G G G Sbjct: 1124 ---------PGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGK 1174 Query: 1009 ASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEV 1068 G G+PGP GPPGP G G ++ PGPPG PG GP A + Sbjct: 1175 D----GANGIPGPIGPPGPRGRSG----ETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGL 1226 Query: 1069 GPPGPPGQFPFDFLQLEAEMKG 1090 G P G P +++ + G Sbjct: 1227 G-PREKGPDPLQYMRADQAAGG 1247 Score = 372 bits (955), Expect = e-102 Identities = 258/648 (39%), Positives = 293/648 (45%), Gaps = 105/648 (16%) Query: 422 DDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEE 481 D GA+G G G A E R E GA P PP GG + E Sbjct: 635 DGETGAAGPPGPA-GPAGE--RGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA 691 Query: 482 QTTVA------------SLGAQTL---------PGSDSVSTWDGSVRTPGGRVKEG--GL 518 V S GAQ L PG+D G PG + G G+ Sbjct: 692 PGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGM 751 Query: 519 KGQKGEPGVPGPPG------RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPP 572 G++G G+ GP G GP G+P G GL P+ P GPAG G +G Sbjct: 752 PGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAG-----ANGEKGEV 806 Query: 573 GPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQ 631 GPPG G+ G G PG+ GE G PG G G PG G G KG++G+ G G+ G PGPQ Sbjct: 807 GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 866 Query: 632 GP---PGPPGPSFRHDKLTFIDMEG----SGFGGDLEALRGPRGFPGPPGPPGVPGLPGE 684 GP PGP GP+ +G +GF G + GP G G PGPPG PG G+ Sbjct: 867 GPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRV-GPPGSNGNPGPPGPPGPSGK 925 Query: 685 PGRFGVNS-SDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGA 743 G G S PG AG PG+ G GPPG G PG GP G EGPPG G G G G Sbjct: 926 DGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGL 985 Query: 744 PGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWS 803 PG +G +G PG G GE G GAPG +G GPPGP GPPG PAG EGS G Sbjct: 986 PGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPG---- 1041 Query: 804 TARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDR 863 ADGP G G G+KGD +GE GA G PG PG PG G AGP G +GDR Sbjct: 1042 ----ADGPPGRDGAAGVKGD---------RGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1088 Query: 864 GSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAG 922 G G +G G G G G+ GP GP G E L G G G G PGP G Sbjct: 1089 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLK--GHRGFTGLQGLPGPPG 1146 Query: 923 PKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYK 982 P G+ G+ G G GP+G G G P G + GA G PG GPPGP GR G Sbjct: 1147 PSGDQGASGPAGPSGPRGPPGPVG----PSG------KDGANGIPGPIGPPGPRGRSGET 1196 Query: 983 GEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGP 1030 G G PG P GPPGPPGPPGP Sbjct: 1197 GPAGPPGNP----------------------------GPPGPPGPPGP 1216 Score = 234 bits (598), Expect = 4e-61 Identities = 164/461 (35%), Positives = 188/461 (40%), Gaps = 58/461 (12%) Query: 426 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 485 G G +GS R ETG P P PP A G E ++ Sbjct: 807 GPPGPAGSAGARGAPGERGETGP------PGPAGFAGPPGADGQPGAKGEQGEAGQKGDA 860 Query: 486 ASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGP 545 + G Q G+ G G R G +G G G PG GR GPPGS PGP Sbjct: 861 GAPGPQGPSGAPGPQGPTGVTGPKGAR----GAQGPPGATGFPGAAGRVGPPGSNGNPGP 916 Query: 546 PGLPCPVSPLGPAG-------PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGK--- 595 PG P P GP G P PG QGP GPPG G PG DG G G G Sbjct: 917 PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 976 Query: 596 ---------PGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDK 645 PG G +GFPG PG G G +G PG G+RGPPGP GPPG GP+ + Sbjct: 977 AGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGR 1036 Query: 646 LTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSD----------- 694 +G ++G RG G G PG PG PG PG G Sbjct: 1037 EGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1096 Query: 695 --VPGPAGLPGVPGREGP---------PGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGA 743 GPAG G+ G +GP PG GL G G G +G PG G G G +G Sbjct: 1097 MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP 1156 Query: 744 PGHKGSKGAPGPAGARGESGLAGAPGPAGPPGP------PGPPGPPGPGLPAGFDDMEGS 797 G G +G PGP G G+ G G PGP GPPGP GP GPPG P G G Sbjct: 1157 AGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGP 1216 Query: 798 GGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGA 838 G + A +GP L ++ D GL EV A Sbjct: 1217 GIDMSAFAGLGPREKGPDPLQYMRADQAAGGLRQHDAEVDA 1257 Score = 88.6 bits (218), Expect = 4e-17 Identities = 79/244 (32%), Positives = 92/244 (37%), Gaps = 49/244 (20%) Query: 1096 GDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI 1155 G G KG++GEPG + GP GPPGP+G G GP+G+ RG G G GP Sbjct: 98 GQPGPKGQKGEPGDI----KDIVGPKGPPGPQGPAGEQGPRGD--RGDKGEKGAPGP--- 148 Query: 1156 GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQA 1215 GR G PG PG PGPP GPPGPPGPPG G A Sbjct: 149 --RGRDGEPGTPGNPGPP-------------GPPGPPGPPGLGGNFAAQ----------- 182 Query: 1216 MLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLH 1275 M G E G + V + G R A P P+G P V Sbjct: 183 MAGGFDEKAGGAQLGVMQGP----MGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGV--- 235 Query: 1276 DSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHS 1335 S P R P P +P DD A P + PG + P P P Sbjct: 236 -SGPMGPRGPPGPPGKP--GDDGEAGKPGKAGERGPPGPQGARGF----PGTPGLPGVKG 288 Query: 1336 HRDF 1339 HR + Sbjct: 289 HRGY 292 Score = 43.1 bits (100), Expect = 0.002 Identities = 50/172 (29%), Positives = 58/172 (33%), Gaps = 20/172 (11%) Query: 46 PEPQGPLPVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEE 105 P P GP P + EP G PP E E G D P+ AE P P+ Sbjct: 917 PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQ-GPAGPPGEKGEPGDDGPSGAEGPPGPQG 975 Query: 106 NIAGVGAEILNVAKGIRSFVQL-------WNDTVPTESLARAETLVLETPVGPLALAGPS 158 G L +G R F L P S R PVGP L GP+ Sbjct: 976 LAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGP----PGPVGPPGLTGPA 1031 Query: 159 STPQENGTTLWPSRGIPSSPGA-----HTTEAGTLPAP-TPSPPSLGRPWAP 204 P G+ + G P GA E G + AP P PP P P Sbjct: 1032 GEPGREGSP--GADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGP 1081 Score = 32.0 bits (71), Expect = 4.7 Identities = 42/165 (25%), Positives = 54/165 (32%), Gaps = 15/165 (9%) Query: 46 PEPQGPLPVQPTADTTTHVTPRNGSTEPATA--PGSPEPPSELLEDGQDTPTSAESPDAP 103 P P GP + P+ + EP A G P P G+D T A P P Sbjct: 587 PGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP 646 Query: 104 EENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSST--- 160 G + A G F L P + + G L GP Sbjct: 647 AGPAGERGEQ---GAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 703 Query: 161 PQENGTT----LWPSRGIPSSPGAHTTEAGTLPAPTP---SPPSL 198 P E G+ L RG+P +PG + + PA P PP L Sbjct: 704 PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGL 748 Score = 31.2 bits (69), Expect = 8.0 Identities = 49/191 (25%), Positives = 61/191 (31%), Gaps = 25/191 (13%) Query: 33 FNNEDTSHAATTIPEPQGPLPVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQD 92 F E S A + P+G LP P D G++ PA PG+ PP G+ Sbjct: 703 FPGERGSPGAQGLQGPRG-LPGTPGTDGP------KGASGPAGPPGAQGPPGLQGMPGER 755 Query: 93 TPTSAESPDAPEENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGPL 152 P ++ G E G R P + + P GP Sbjct: 756 GAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEV---GPPGPA 812 Query: 153 ALAGPSSTPQENGTTLWPS-RGIPSSPGA-----------HTTEAGTLPAPTPSPPS-LG 199 AG P E G T P G PGA + G AP P PS Sbjct: 813 GSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAP 872 Query: 200 RPWAP--LTGP 208 P P +TGP Sbjct: 873 GPQGPTGVTGP 883 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 530 bits (1365), Expect = e-150 Identities = 407/1117 (36%), Positives = 460/1117 (41%), Gaps = 252/1117 (22%) Query: 419 EEGDDSD-GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSE 477 E+G D G G+ G+ R+ E G P P PP PP GG+ Sbjct: 61 EQGPRGDRGDKGEKGAPGPRGRD---GEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGG 117 Query: 478 EVEEQTTVASLGAQTLP-GSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGP 536 +E+ A LG P G G PG + +G G+ GEPGV GP G GP Sbjct: 118 -FDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGN-PGEPGEPGVSGPMGPRGP 175 Query: 537 PGSPCLPGP------PGLPCPVSPLGPAG----PALQTVPGPQGPPGPPGRDGT------ 580 PG P PG PG P GP G P +PG +G G PG DG Sbjct: 176 PGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGA 235 Query: 581 PGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPS 640 PG GE G PGE+G PG GP+G PG G GP G G G G PGP GPPGP GP+ Sbjct: 236 PGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAG--ARGNDGQPGPAGPPGPVGPA 293 Query: 641 FRHDKLTFIDMEGSGFGG--------------DLEALRGPRGFPGPPGPPGVPGLPGEPG 686 G GF G E +GPRG PG PG PG G G PG Sbjct: 294 -----------GGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPG 342 Query: 687 RFGV----NSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAG 742 G+ S+ PG AG PG PG GPPG G GP GP G+ G PG G KG G G Sbjct: 343 TDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKG 402 Query: 743 APGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG------------------ 784 PG G +GAPGPAG G+ G G PG GP GPPG G PG Sbjct: 403 EPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPG 462 Query: 785 ----------------------PGLPA--GFDDMEGSGGPFW----STARSADGPQGPPG 816 PGLP G G GP S A DG GPPG Sbjct: 463 ERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPG 522 Query: 817 LPGLKGDPGVPGLPGAK---------GEVGADGVPGFPGLPGRE---GIAGPQGPKGDRG 864 G +G PGV G PG K GE G G PG GLPG++ G AGP GP G G Sbjct: 523 PQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAG 582 Query: 865 SRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPK 924 RGE+G PG G GLPGPPGPPG + G PG +G PG AG PG GP+ Sbjct: 583 ERGEQGAPGPSGF--QGLPGPPGPPG-------EGGK----PGDQGVPGEAGAPGLVGPR 629 Query: 925 GNLGSKGERGSPGPKGEKGEPGSIFSP--DG--GALGPA-QKGAKGEPGFR--------- 970 G G GERGSPG +G +G G +P DG GA GPA GA+G PG + Sbjct: 630 GERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAA 689 Query: 971 ---------------------------------GPPGPYGRPGYKGEIGFPGRPGRPGMN 997 GPPGP G G KGE+G PG G G Sbjct: 690 GIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGAR 749 Query: 998 GLKGEKGEPG-DASLGF----------------------GMRGMPGPPGPPGPPGPPGT- 1033 G GE+GE G GF G G PGP GP G PGP G Sbjct: 750 GAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPT 809 Query: 1034 -------------PVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGP------PGPP 1074 P + + R GPPG GN GPPGP G G+ GP GPP Sbjct: 810 GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP 869 Query: 1075 GQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIP 1133 G+ LQ A GEKG+ GD G G G PG G G + G PG G RG+PG+P Sbjct: 870 GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLP 929 Query: 1134 GPKGE-------SIRGQPGPPGPQGPPGI----GYEGRQGPPGPPGPPGPPSFPG----- 1177 GP GE G GPPGP GPPG+ G GR+G PG GPPG G Sbjct: 930 GPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDR 989 Query: 1178 PHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLG----------QVHEVPEGW 1227 + PG PGPPG PGP G G G R A Q +G Q + P G Sbjct: 990 GETGAVGAPGAPGPPGSPGPAGPTG-KQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGD 1048 Query: 1228 LIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQP-----PVVQLHDSNPYPR 1282 E E ++ GF +Q P P G P P + S Sbjct: 1049 KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGA 1108 Query: 1283 REHPHPTARPW----RADDILASPPRLPEPQPYPGAP 1315 P P P + A PP P P PG P Sbjct: 1109 NGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPP 1145 Score = 523 bits (1347), Expect = e-148 Identities = 335/807 (41%), Positives = 378/807 (46%), Gaps = 149/807 (18%) Query: 509 PGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSP-------------- 554 P G G +G KGE G PGP GR G PG+P PGPPG P P P Sbjct: 58 PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGG 117 Query: 555 -------------LGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGP 601 GP GP GP+GPPGP G G G G PG+PGE G G GP Sbjct: 118 FDEKAGGAQLGVMQGPMGPM-----GPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGP 172 Query: 602 QGFPGTPGDVGPKGDKGDPG-VGERGPPGPQGP---PGPPGPSFRHDKLTFIDMEGSGFG 657 +G PG PG G G+ G PG GERGPPGPQG PG PG + ++G+ Sbjct: 173 RGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGE 232 Query: 658 GDLEALRGPRGFP---GPPGPPGVPGLPGEPGRFGV-------NSSDVPGPAGLPGVPGR 707 ++G G P G PGP G GLPGE GR G + PGPAG PG G Sbjct: 233 AGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGP 292 Query: 708 EGPPGFPGLPGPP---------GPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGA 758 G PGFPG PG GP G +GP G G GS G AGA G+ G+ G PG G+ Sbjct: 293 AGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGS 352 Query: 759 RGESGLAGAPGPAGPPGPPGPPGPPGPGLP------AGFDDMEGSGGPFWSTARSADGPQ 812 G G+AGAPG GP GPPGP G GP P G +G GP + GPQ Sbjct: 353 AGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPA--GPQ 410 Query: 813 GPPGLPGLKGDPGVPGLPGAKGEVGAD---GVPGFPGLPGREGIAGPQGPKGDRGSRGEK 869 G PG G +G G G PG G +G G PG G PG++G+AGP+G G+RG G Sbjct: 411 GAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLA 470 Query: 870 GDPGKDGVGQPGLPGPPGPPGPVVYVSEQ-DGSVLSVPGPEGRPGFAGFPGPAGPKGNLG 928 G G + G PG PG PG PG D GP G PG G PGP GP+G G Sbjct: 471 GPKGAN--GDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARG 528 Query: 929 SKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFP 988 G G PGPKG GEPG GE G G PG G PG GE G Sbjct: 529 QPGVMGFPGPKGANGEPGK----------------AGEKGLPGAPGLRGLPGKDGETGAA 572 Query: 989 GRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRP- 1047 G PG G G +GE+G PG + G +G+PGPPGPPG G PG D V E+ P Sbjct: 573 GPPGPAGPAGERGEQGAPGPS----GFQGLPGPPGPPGEGGKPG----DQGVPGEAGAPG 624 Query: 1048 -----------------------GPPGLPGNQGPPGPKGAKGEVGPP---GPPGQFPFDF 1081 GP GLPG G GPKGA G GPP GPPG Sbjct: 625 LVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPG 684 Query: 1082 LQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGP------RGYPGIPGP 1135 + A + G KGDRGD G+KG G PG G G L GP GPPGP +G G PGP Sbjct: 685 ERGAAGIAGPKGDRGDVGEKGPEGAPGKDG--GRGLTGPIGPPGPAGANGEKGEVGPPGP 742 Query: 1136 KGES-------IRGQPGPPGP---QGPPGI----------GYEGRQGPPGPPGPPGPPSF 1175 G + RG+ GPPGP GPPG G G++G G PGP GP Sbjct: 743 AGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGA 802 Query: 1176 PGPHRQTISVPGPPGPPGPPGPPGTMG 1202 PGP T V GP G G GPPG G Sbjct: 803 PGPQGPT-GVTGPKGARGAQGPPGATG 828 Score = 518 bits (1334), Expect = e-146 Identities = 331/766 (43%), Positives = 374/766 (48%), Gaps = 99/766 (12%) Query: 489 GAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGL 548 G + PG D ++ G PG R GL G KG G PG PG G PG+ L G PG Sbjct: 444 GNRGFPGQDGLA---GPKGAPGER-GPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGD 499 Query: 549 PCPVSPLGPAG-PALQTVPGPQGP------------PGPPGRDGTPGRDGE---PGDPGE 592 P +GP+G P PGP GP PGP G +G PG+ GE PG PG Sbjct: 500 AGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL 559 Query: 593 DGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDME 652 G PG G G G PG GP G++G+ G GP G QG PGPPGP K + Sbjct: 560 RGLPGKDGETGAAGPPGPAGPAGERGEQGAP--GPSGFQGLPGPPGPPGEGGKPGDQGVP 617 Query: 653 GSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP-GPAGLPGVPGREGPP 711 G L RG RGFPG G PG GL G G G +D P G +G G PG +GPP Sbjct: 618 GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPP 677 Query: 712 GFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA------PGPAGARGESGLA 765 G G+PG G G GP G G G G GAPG G +G PGPAGA GE G Sbjct: 678 GLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEV 737 Query: 766 GAPGPAGPPGP---------PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSAD----GPQ 812 G PGPAG G GPPGP G P G D G+ G + D GPQ Sbjct: 738 GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 797 Query: 813 GPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGR---------EGIAGPQGPKGDR 863 GP G PG +G GV G GA+G G G GFPG GR G GP GP G Sbjct: 798 GPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKD 857 Query: 864 GSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAG 922 G +G +GD G G G+PGL GP GPPG G G G +G GP G Sbjct: 858 GPKGARGDSGPPGRAGEPGLQGPAGPPGE--------------KGEPGDDGPSGAEGPPG 903 Query: 923 PKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYK 982 P+G G +G G PG +GE+G PG + P G P ++GA G G RGPPGP G PG Sbjct: 904 PQGLAGQRGIVGLPGQRGERGFPG-LPGPSGE---PGKQGAPGASGDRGPPGPVGPPGLT 959 Query: 983 GEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFA 1042 G G PGR G PG +G G G G G RG G G PG PGPPG+P Sbjct: 960 GPAGEPGREGSPGADGPPGRDGAAGVK----GDRGETGAVGAPGAPGPPGSP-------- 1007 Query: 1043 ESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKG 1102 GP G G QG G GA+G +GP GP G Q G +GD+G+AG+ G Sbjct: 1008 -----GPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQ------GPRGDKGEAGEPG 1056 Query: 1103 ERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI-GYEGRQ 1161 ERG G GF G L G PGPPGP G G GP G S G GPPGP GP G G G Sbjct: 1057 ERGLKGHRGFTG--LQGLPGPPGPSGDQGASGPAGPS--GPRGPPGPVGPSGKDGANGIP 1112 Query: 1162 GPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGV 1207 GP GPPGP G GP + PGPPGPPGPPGP M A +G+ Sbjct: 1113 GPIGPPGPRGRSGETGPAGPPGN-PGPPGPPGPPGPGIDMSAFAGL 1157 Score = 404 bits (1037), Expect = e-112 Identities = 280/742 (37%), Positives = 332/742 (44%), Gaps = 114/742 (15%) Query: 426 GASGDSGS----GLGDARELLREE-----------TGAALKPRLPAPPPVT----TPPLA 466 GA+GD G GL AR L +GA + P PP P + Sbjct: 474 GANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVM 533 Query: 467 GGSSTEDSRSE--EVEEQTTVASLGAQTLPGSDS---VSTWDGSVRTPGGRVKEG--GLK 519 G + + E + E+ + G + LPG D + G G R ++G G Sbjct: 534 GFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPS 593 Query: 520 GQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG-PALQTVPGPQGPPGPPGRD 578 G +G PG PGPPG G PG +PG G P V P G G P + PG QG GP G Sbjct: 594 GFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP 653 Query: 579 GTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGD------VGPKGDKGDPGVGERGPPGPQG 632 GTPG DG G G G PG GP G G PG+ GPKGD+GD VGE+GP G G Sbjct: 654 GTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD--VGEKGPEGAPG 711 Query: 633 ---------PPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPG 683 P GPPGP+ + + + G G RG GPPGP G G PG Sbjct: 712 KDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPG 771 Query: 684 EPGRFGVNSSD----------VPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTG 733 G+ G PGP G G PG +GP G + GP G G +GPPG TG Sbjct: 772 ADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTG---VTGPKGARGAQGPPGATG 828 Query: 734 QKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDD 793 G+ G G PG G+ G PGP G G+ G GA G +GPPG G PG GP P G Sbjct: 829 FPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG 888 Query: 794 MEGSGGPFWSTARSADGPQGPPG------LPGLKGDPGVPGLPGAKGEVGADGVPGF--- 844 G GP S A GPQG G LPG +G+ G PGLPG GE G G PG Sbjct: 889 EPGDDGP--SGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGD 946 Query: 845 ---------PGL------PGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGP 888 PGL PGREG G GP G G+ G KGD G+ G VG PG PGPPG Sbjct: 947 RGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS 1006 Query: 889 PGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSI 948 PGP G +G G AG GP GP G G++G +G GP+G+KGE G Sbjct: 1007 PGPA-----------GPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGE- 1054 Query: 949 FSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGD 1008 P ++G KG GF G G G PG G+ G G G G G G G G Sbjct: 1055 ---------PGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGK 1105 Query: 1009 ASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEV 1068 G G+PGP GPPGP G G ++ PGPPG PG GP A + Sbjct: 1106 D----GANGIPGPIGPPGPRGRSG----ETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGL 1157 Query: 1069 GPPGPPGQFPFDFLQLEAEMKG 1090 G P G P +++ + G Sbjct: 1158 G-PREKGPDPLQYMRADQAAGG 1178 Score = 376 bits (966), Expect = e-104 Identities = 251/624 (40%), Positives = 277/624 (44%), Gaps = 162/624 (25%) Query: 702 PGVPGREGPPG-FPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARG 760 PG G++G PG + GP GPPG +GP G G +G G+ KG KGAPGP G G Sbjct: 31 PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGD------KGEKGAPGPRGRDG 84 Query: 761 ESGLAGAPGPAGPPGPPGPP------------------------------------GPPG 784 E G G PGP GPPGPPGPP GPPG Sbjct: 85 EPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPG 144 Query: 785 PG---LPAGFDDMEG----------------------------SGGPFWSTARSADGPQ- 812 P P GF G +G P + R GPQ Sbjct: 145 PAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQG 204 Query: 813 -----GPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRG 867 G PGLPG+KG G PGL GAKGE GA GV G G PG G GP GP+G G RG Sbjct: 205 ARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERG 264 Query: 868 EKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGN 926 G G G G G PGP GPPGPV GP G PGF G PG G G Sbjct: 265 RTGPAGAAGARGNDGQPGPAGPPGPV--------------GPAGGPGFPGAPGAKGEAGP 310 Query: 927 LGSKGERGSPGPKGEKGEPGS--------------IFSPDGGALGPAQKGAKGEPGFRGP 972 G++G G+ GP+GE G PGS I G A P GA G PG RGP Sbjct: 311 TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP 370 Query: 973 PGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASL-----------GFGMRGMPGP 1021 PGP G G G G G PG G G +G KGEPG A G RG PG Sbjct: 371 PGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGG 430 Query: 1022 PGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGP---PGPKGAKGEVGPPGPPGQFP 1078 GP GPPG G P + + GP G PG +GP GPKGA G+ G PG PG Sbjct: 431 VGPIGPPGERGAP-GNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPG--- 486 Query: 1079 FDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGI---PGP 1135 L + G GD G G+ G G PG G PGPPGP G RG PG+ PGP Sbjct: 487 ---LPGARGLTGRPGDAGPQGKVGPSGAPGEDG-----RPGPPGPQGARGQPGVMGFPGP 538 Query: 1136 KGES-------IRGQPGPPGPQGPPG-IGYEGRQGPPGPPGP---------PGPPSFPGP 1178 KG + +G PG PG +G PG G G GPPGP GP PGP F G Sbjct: 539 KGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQG- 597 Query: 1179 HRQTISVPGPPGPPGPPGPPGTMG 1202 +PGPPGPPG G PG G Sbjct: 598 ------LPGPPGPPGEGGKPGDQG 615 Score = 372 bits (955), Expect = e-102 Identities = 258/648 (39%), Positives = 293/648 (45%), Gaps = 105/648 (16%) Query: 422 DDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEE 481 D GA+G G G A E R E GA P PP GG + E Sbjct: 566 DGETGAAGPPGPA-GPAGE--RGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA 622 Query: 482 QTTVA------------SLGAQTL---------PGSDSVSTWDGSVRTPGGRVKEG--GL 518 V S GAQ L PG+D G PG + G G+ Sbjct: 623 PGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGM 682 Query: 519 KGQKGEPGVPGPPG------RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPP 572 G++G G+ GP G GP G+P G GL P+ P GPAG G +G Sbjct: 683 PGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAG-----ANGEKGEV 737 Query: 573 GPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQ 631 GPPG G+ G G PG+ GE G PG G G PG G G KG++G+ G G+ G PGPQ Sbjct: 738 GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 797 Query: 632 GP---PGPPGPSFRHDKLTFIDMEG----SGFGGDLEALRGPRGFPGPPGPPGVPGLPGE 684 GP PGP GP+ +G +GF G + GP G G PGPPG PG G+ Sbjct: 798 GPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRV-GPPGSNGNPGPPGPPGPSGK 856 Query: 685 PGRFGVNS-SDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGA 743 G G S PG AG PG+ G GPPG G PG GP G EGPPG G G G G Sbjct: 857 DGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGL 916 Query: 744 PGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWS 803 PG +G +G PG G GE G GAPG +G GPPGP GPPG PAG EGS G Sbjct: 917 PGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPG---- 972 Query: 804 TARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDR 863 ADGP G G G+KGD +GE GA G PG PG PG G AGP G +GDR Sbjct: 973 ----ADGPPGRDGAAGVKGD---------RGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1019 Query: 864 GSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAG 922 G G +G G G G G+ GP GP G E L G G G G PGP G Sbjct: 1020 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLK--GHRGFTGLQGLPGPPG 1077 Query: 923 PKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYK 982 P G+ G+ G G GP+G G G P G + GA G PG GPPGP GR G Sbjct: 1078 PSGDQGASGPAGPSGPRGPPGPVG----PSG------KDGANGIPGPIGPPGPRGRSGET 1127 Query: 983 GEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGP 1030 G G PG P GPPGPPGPPGP Sbjct: 1128 GPAGPPGNP----------------------------GPPGPPGPPGP 1147 Score = 234 bits (598), Expect = 4e-61 Identities = 164/461 (35%), Positives = 188/461 (40%), Gaps = 58/461 (12%) Query: 426 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 485 G G +GS R ETG P P PP A G E ++ Sbjct: 738 GPPGPAGSAGARGAPGERGETGP------PGPAGFAGPPGADGQPGAKGEQGEAGQKGDA 791 Query: 486 ASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGP 545 + G Q G+ G G R G +G G G PG GR GPPGS PGP Sbjct: 792 GAPGPQGPSGAPGPQGPTGVTGPKGAR----GAQGPPGATGFPGAAGRVGPPGSNGNPGP 847 Query: 546 PGLPCPVSPLGPAG-------PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGK--- 595 PG P P GP G P PG QGP GPPG G PG DG G G G Sbjct: 848 PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 907 Query: 596 ---------PGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDK 645 PG G +GFPG PG G G +G PG G+RGPPGP GPPG GP+ + Sbjct: 908 AGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGR 967 Query: 646 LTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSD----------- 694 +G ++G RG G G PG PG PG PG G Sbjct: 968 EGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1027 Query: 695 --VPGPAGLPGVPGREGP---------PGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGA 743 GPAG G+ G +GP PG GL G G G +G PG G G G +G Sbjct: 1028 MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP 1087 Query: 744 PGHKGSKGAPGPAGARGESGLAGAPGPAGPPGP------PGPPGPPGPGLPAGFDDMEGS 797 G G +G PGP G G+ G G PGP GPPGP GP GPPG P G G Sbjct: 1088 AGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGP 1147 Query: 798 GGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGA 838 G + A +GP L ++ D GL EV A Sbjct: 1148 GIDMSAFAGLGPREKGPDPLQYMRADQAAGGLRQHDAEVDA 1188 Score = 99.0 bits (245), Expect = 3e-20 Identities = 58/148 (39%), Positives = 74/148 (50%), Gaps = 20/148 (13%) Query: 1072 GPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPG 1131 G P L + A ++ + D G KG++GEPG + GP GPPGP+G G Sbjct: 5 GAPQTLVLLTLLVAAVLRCQGQDVRQPGPKGQKGEPGD----IKDIVGPKGPPGPQGPAG 60 Query: 1132 IPGPKGE-SIRGQPGPPGPQGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTIS----- 1184 GP+G+ +G+ G PGP+G G G G GPPGPPGPPGPP G ++ Sbjct: 61 EQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDE 120 Query: 1185 ---------VPGPPGPPGPPGPPGTMGA 1203 + GP GP GP GPPG GA Sbjct: 121 KAGGAQLGVMQGPMGPMGPRGPPGPAGA 148 Score = 43.1 bits (100), Expect = 0.002 Identities = 50/172 (29%), Positives = 58/172 (33%), Gaps = 20/172 (11%) Query: 46 PEPQGPLPVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEE 105 P P GP P + EP G PP E E G D P+ AE P P+ Sbjct: 848 PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQ-GPAGPPGEKGEPGDDGPSGAEGPPGPQG 906 Query: 106 NIAGVGAEILNVAKGIRSFVQL-------WNDTVPTESLARAETLVLETPVGPLALAGPS 158 G L +G R F L P S R PVGP L GP+ Sbjct: 907 LAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGP----PGPVGPPGLTGPA 962 Query: 159 STPQENGTTLWPSRGIPSSPGA-----HTTEAGTLPAP-TPSPPSLGRPWAP 204 P G+ + G P GA E G + AP P PP P P Sbjct: 963 GEPGREGSP--GADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGP 1012 Score = 32.0 bits (71), Expect = 4.7 Identities = 42/165 (25%), Positives = 54/165 (32%), Gaps = 15/165 (9%) Query: 46 PEPQGPLPVQPTADTTTHVTPRNGSTEPATA--PGSPEPPSELLEDGQDTPTSAESPDAP 103 P P GP + P+ + EP A G P P G+D T A P P Sbjct: 518 PGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP 577 Query: 104 EENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSST--- 160 G + A G F L P + + G L GP Sbjct: 578 AGPAGERGEQ---GAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 634 Query: 161 PQENGTT----LWPSRGIPSSPGAHTTEAGTLPAPTP---SPPSL 198 P E G+ L RG+P +PG + + PA P PP L Sbjct: 635 PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGL 679 Score = 31.2 bits (69), Expect = 8.0 Identities = 49/191 (25%), Positives = 61/191 (31%), Gaps = 25/191 (13%) Query: 33 FNNEDTSHAATTIPEPQGPLPVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQD 92 F E S A + P+G LP P D G++ PA PG+ PP G+ Sbjct: 634 FPGERGSPGAQGLQGPRG-LPGTPGTDGP------KGASGPAGPPGAQGPPGLQGMPGER 686 Query: 93 TPTSAESPDAPEENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGPL 152 P ++ G E G R P + + P GP Sbjct: 687 GAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEV---GPPGPA 743 Query: 153 ALAGPSSTPQENGTTLWPS-RGIPSSPGA-----------HTTEAGTLPAPTPSPPS-LG 199 AG P E G T P G PGA + G AP P PS Sbjct: 744 GSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAP 803 Query: 200 RPWAP--LTGP 208 P P +TGP Sbjct: 804 GPQGPTGVTGP 814 >gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo sapiens] Length = 1629 Score = 528 bits (1359), Expect = e-149 Identities = 387/1039 (37%), Positives = 474/1039 (45%), Gaps = 161/1039 (15%) Query: 246 LAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIR--PATEGPGVLFAITDSAQAMVLLGV 303 +AY A R FP F +DFSLL +R P + P + SAQ + LG+ Sbjct: 58 VAYRVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLY---SAQGVRQLGL 114 Query: 304 KLSGVQDGHQDISLLYTEP-GAGQTHTAASFR-LPAFVGQWTHLALSVAGGFVALYVDCE 361 +L + + LY + G Q + FR L G+W +A++V G V L VDC+ Sbjct: 115 ELG------RPVRFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCK 168 Query: 362 EFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEG 421 + PL RS+R + G +F A+ D + F+G + EL + Q + C +E Sbjct: 169 KRVTRPLPRSARPVLDTHGVIIFGARI--LDEEVFEGDVQELAIVPGVQAAYESCEQKE- 225 Query: 422 DDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEE 481 L E G +P+ P P S +++E + Sbjct: 226 --------------------LECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQS 265 Query: 482 QTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGL---------KGQKGEPGVPGPPG 532 Q G + G +V V P G GL G G+PG GPPG Sbjct: 266 QAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPG 325 Query: 533 RAGPPGSPCLPGPPGLPCPV-----SPLGPAGPAL------------QTVPGPQGPPGPP 575 RAG PGS PGPPG + S G GP + Q +GPPGP Sbjct: 326 RAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPM 385 Query: 576 GRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPG 635 G G PG G+PG PG G+ GD GPQG G G GP G G G G G +G PG Sbjct: 386 GYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRG--RAGADGARGMPG 443 Query: 636 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 695 PG + D+ GF G L L G +G G G G+PG PGE G G + Sbjct: 444 DPG--VKGDR---------GFDG-LPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI- 490 Query: 696 PGPAGLPGVPGREG---PPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGS--- 749 GP GLPG G G P G PG+PGPPG G +GP G G G GE G PG +G+ Sbjct: 491 -GPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT 549 Query: 750 KGAPGPAGA---RGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTAR 806 +G PGP GA GE G G PG G PG GPPG PG P G +G GP Sbjct: 550 QGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGP------ 603 Query: 807 SADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPG------------LPGREGIA 854 GP G PG G+KG G+ GL G KGE G DG PGF G +PG G Sbjct: 604 --QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED 661 Query: 855 GPQGPKGDRGSRGEKGDPG----KDGVGQPGLPGPPGPPGPVVYVSEQDGSV--LSVPGP 908 GP+GPKG G G+ G PG K +G PGLPG PG GP GS+ PG Sbjct: 662 GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGP-------KGSLGFPGFPGA 714 Query: 909 EGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDG-------GALG-PAQ 960 G G G G +GP+G G G RG GP+G G+ G+ + G G G P Sbjct: 715 SGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGP 774 Query: 961 KGAKGEPGFRGPPGPYGR------PGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFG 1014 +G G PG +GPPGP G+ PG +GE+GF G+ G PG G+ G +G G+ G Sbjct: 775 QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG-PMG 833 Query: 1015 MRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPP 1074 RG PGPPGPPG G PGT + PGPPG PG GP G +G GE G PG Sbjct: 834 ERGHPGPPGPPGEQGLPGTAGKEGT----KGDPGPPGAPGKDGPAGLRGFPGERGLPGTA 889 Query: 1075 GQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIP 1133 G +G G G AG GERG G GG G PGP GPPG G G+P Sbjct: 890 GGPGLK------GNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVP 943 Query: 1134 GPKG-------ESIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPHRQTISV 1185 G KG + ++G G PGP GPPG+ G +G +G G PG G G H Sbjct: 944 GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEH------ 997 Query: 1186 PGPPGPPGPPGPPGTMGAS 1204 GPPGPPGP GP G GA+ Sbjct: 998 -GPPGPPGPIGPVGQPGAA 1015 Score = 523 bits (1346), Expect = e-148 Identities = 358/865 (41%), Positives = 397/865 (45%), Gaps = 193/865 (22%) Query: 489 GAQTLPGSDSVSTWDGSVRTPG--GRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPP 546 GAQ LPG PG G + G G +G PG GP G GP G P +PGPP Sbjct: 470 GAQGLPGP------------PGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPP 517 Query: 547 GLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPG 606 G+ P GP G GPQG PGPPG+ GTPG G PG G G G+ GPQG PG Sbjct: 518 GVRGMDGPQGPKGSL-----GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPG 572 Query: 607 TPGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS----- 654 PG G G G PG G +GP GPQGP G PGP ++G Sbjct: 573 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 632 Query: 655 -----GFGGDL-----------------EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNS 692 GF GD+ + GP+G GP G PG PGL GE G+ GV Sbjct: 633 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGV-- 690 Query: 693 SDVPGPAGLPGVPGREGP------PGFPG---------LPGPPGPPGREGPPGRTGQKGS 737 GLPG PGR+GP PGFPG L G GP G GP G GQ+G Sbjct: 691 ------PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGP 744 Query: 738 LGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGLPA---- 789 G G G KG+ G GP G GE GL G GP G PGP GPPGPPG PG P Sbjct: 745 RGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGE 804 Query: 790 -GFDDMEGSGGPFWSTA-------------RSADGPQGPPGLPGL---------KGDPGV 826 GF G GP R GP GPPG GL KGDPG Sbjct: 805 VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGP 864 Query: 827 PGLPGAKGEVGADGVPGFPGLPGR------EGIAGPQGPKGDRGSRGEKGDPGKDG-VGQ 879 PG PG G G G PG GLPG +G GP GP G GS GE+G G G +G Sbjct: 865 PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGP 924 Query: 880 PGLPGPPGPPGPVVY--VSEQDGSVLSVPGPEGRPGF---AGFPGPAGP---------KG 925 PG PGP GPPG V + G + GP GR G G PGPAGP KG Sbjct: 925 PGRPGPQGPPGAAGEKGVPGEKGPI----GPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 980 Query: 926 NLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEI 985 +G G++G+ G KGE G PG P G P GA GEPG RGP G +G G +G Sbjct: 981 EVGDPGQKGTKGNKGEHGPPGPP-GPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1039 Query: 986 GFPGRPGRPGMNGL---KGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFA 1042 GF G PG G+ GL GEKGE GD G G PGPPGP GP GP G Sbjct: 1040 GFNGPPGPIGLQGLPGPSGEKGETGDV----GPMGPPGPPGPRGPAGPNGA--------- 1086 Query: 1043 ESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKG 1102 GPPG GN GPPG KG GE G PG +Q E +KG +G+RG+ G+ G Sbjct: 1087 -DGPQGPPGGVGNLGPPGEKGEPGESGSPG---------IQGEPGVKGPRGERGEKGESG 1136 Query: 1103 ERGEPGGGGFFG-SSLPGPPGPPGPRGYPGIPGPKGES----------IRGQPGPPGPQG 1151 + GEPG G G + GP G PGP G+PG PGP GE RG+ G PG G Sbjct: 1137 QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG 1196 Query: 1152 PPGIGYEGRQGPPGPPGPPGPPSFPGPHRQ-----------TISVPG------PPGPPGP 1194 PG G GPPGP G GP PG + I PG P GP G Sbjct: 1197 SPGP--TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1254 Query: 1195 PGPPGTMGASSGV----RLWATRQA 1215 PGP G G V R AT QA Sbjct: 1255 PGPDGLRGLPGSVGQQGRPGATGQA 1279 Score = 432 bits (1112), Expect = e-121 Identities = 306/763 (40%), Positives = 350/763 (45%), Gaps = 146/763 (19%) Query: 489 GAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGL 548 GA G+ S DG PG R GL G +G G PGP G GPPG LPG PG Sbjct: 746 GATGKSGAKGTSGGDGPHGPPGER----GLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQ 801 Query: 549 ------------PCPVSPLGPAGPALQTVP----GPQGPPGPPGRDGTPG---RDGEPGD 589 P P +GP G A +T P G GPPGPPG G PG ++G GD Sbjct: 802 RGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD 861 Query: 590 PGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTF 648 PG G PG GP G G PG+ G G G PG+ G GP GP GP G PG Sbjct: 862 PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG---------- 911 Query: 649 IDMEGSGFGGDLEALRGPRGFPGPPGPPGVPG---LPGEPGRFGVNSSD-------VPGP 698 + +G GG + GP G PGP GPPG G +PGE G G D +PGP Sbjct: 912 -ERGAAGSGGPI----GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGP 966 Query: 699 AGLPGV------------PGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGH 746 AG PGV PG++G G G GPPGPPG GP G+ G G+ GE GA G Sbjct: 967 AGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGP 1026 Query: 747 KGSKGAPGPAGARGESG------LAGAPGPAGPPG------PPGPPGPPGPGLPAGFDDM 794 +G GA G G RG +G L G PGP+G G P GPPGPPGP PAG + Sbjct: 1027 QGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGA 1086 Query: 795 EGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIA 854 +G GP GP G G PG G PG+ G PG KG G G G G PG G Sbjct: 1087 DGPQGPPGGVGNL--GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1144 Query: 855 GPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGF 914 GP+GP GD G KG+PG VG PG PGPPG GP QDG+ G +G PG Sbjct: 1145 GPKGPTGDDGP---KGNPGP--VGFPGDPGPPGEGGP----RGQDGAK-GDRGEDGEPGQ 1194 Query: 915 AGFPGPAG---PKGNLGSKGERGSPGP------KGEKGEPGSIFSPDG----GALGPAQK 961 G PGP G P G LG +G GSPG KG KG+PG+I +P G GPA K Sbjct: 1195 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1254 Query: 962 -------------------GAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGE 1002 GA G+ G GP GP G PG +G+ G G G PG+ GL G Sbjct: 1255 PGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGP 1314 Query: 1003 KGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPK 1062 GE G+ G RG+PGP G PG G G P + GPPGLPG GP G K Sbjct: 1315 PGEQGEK----GDRGLPGPQGSPGQKGEMGIPGASGPI----GPGGPPGLPGPAGPKGAK 1366 Query: 1063 GAKGEVGP------------PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGG 1110 GA G GP PGPPG+ L ++ K + G + + P GG Sbjct: 1367 GATGPGGPKGEKGVQGPPGHPGPPGEV-IQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGG 1425 Query: 1111 GFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPP 1153 PG PG G G E I P G Q P Sbjct: 1426 A------PGSPG--GLEEIFGSLDSLREEIEQMRRPTGTQDSP 1460 Score = 380 bits (975), Expect = e-105 Identities = 264/644 (40%), Positives = 293/644 (45%), Gaps = 111/644 (17%) Query: 443 REETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTW 502 R E G K P PP V P A G E E G Q LPG+ Sbjct: 802 RGEVGFQGKTGPPGPPGVVGPQGAAG---ETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 858 Query: 503 DGSVRTPGGRVKEG-----------GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP 551 G PG K+G GL G G PG+ G G +GPPG PG G Sbjct: 859 KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 918 Query: 552 VSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG---PQGFPGTP 608 P+GP G PGPQGPPG G G PG G G G DG G G P G PG Sbjct: 919 GGPIGPPGR-----PGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA 973 Query: 609 GDVGPKGDKGDPGV-------GERGPPGPQGPPGP---PGPSFRHDKLTFIDMEGS-GFG 657 G+ G KG+ GDPG GE GPPGP GP GP PG + + +G G Sbjct: 974 GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK 1033 Query: 658 GDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLP 717 GD G RGF GPPGP G+ GLPG G G + DV GP G PG PG GP G G Sbjct: 1034 GD----EGTRGFNGPPGPIGLQGLPGPSGEKG-ETGDV-GPMGPPGPPGPRGPAGPNGAD 1087 Query: 718 GPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPP 777 GP GPPG G G G+KG GE+G+PG +G G GP G RGE G +G PG GPPGP Sbjct: 1088 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK 1147 Query: 778 GP------------------PGPPGPGLPAGFDDMEGSGG----PFWSTARSADGPQGPP 815 GP PGPPG G P G D +G G P + G GPP Sbjct: 1148 GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPP 1207 Query: 816 GLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKD 875 G G +G G PG G +G GA G PG G PG+ G GP GP G G G +G PG Sbjct: 1208 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1267 Query: 876 GV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERG 934 G G+PG G GPPGPV GP G PG G G G KG+ G G G Sbjct: 1268 GQQGRPGATGQAGPPGPV--------------GPPGLPGLRGDAGAKGEKGHPGLIGLIG 1313 Query: 935 SPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGP---------PGPYGRPGYKGEI 985 PG +GEKG+ G + P G P QKG G PG GP PGP G G KG Sbjct: 1314 PPGEQGEKGDRG-LPGPQGS---PGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGAT 1369 Query: 986 GFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPG 1029 G PG P KGEK G+ GPPG PGPPG Sbjct: 1370 G-PGGP--------KGEK-------------GVQGPPGHPGPPG 1391 Score = 35.8 bits (81), Expect = 0.32 Identities = 64/245 (26%), Positives = 73/245 (29%), Gaps = 68/245 (27%) Query: 47 EPQGPLPVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEEN 106 EP P P PT D G+ P PG P PP E GQD D Sbjct: 1140 EPGPPGPKGPTGDDGP-----KGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQ 1194 Query: 107 IAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGT 166 G PT P GPL GP+ +P G Sbjct: 1195 PGSPG---------------------PTGE---------NGPPGPLGKRGPAGSPGSEGR 1224 Query: 167 TLWPSRGIPSSPGA-----HTTEAGTL-PAPTPSPPSL----------GRPWAP-LTGPS 209 +G PGA T G PA P P L GRP A GP Sbjct: 1225 Q--GGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPP 1282 Query: 210 VP--PPSSERISEEVGLLQLLGDP-------PPQQVTQTDDPDVGLAYVFGPDANSGQVA 260 P PP + + G G P PP + Q + D GL GP + GQ Sbjct: 1283 GPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGE--QGEKGDRGLP---GPQGSPGQKG 1337 Query: 261 RYHFP 265 P Sbjct: 1338 EMGIP 1342 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 527 bits (1358), Expect = e-149 Identities = 364/889 (40%), Positives = 418/889 (47%), Gaps = 149/889 (16%) Query: 426 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 485 G +G +G+ + + R ETG P PV +P L G T+ + Sbjct: 387 GEAGPTGARGPEGPQGQRGETGP--------PGPVGSPGLPGAIGTDGTP---------- 428 Query: 486 ASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG-----GLKGQKGEPGVPGPPGRAGPPGSP 540 GA+ GS S GS PG +G G++GQ G+PGVPG G AGP G P Sbjct: 429 ---GAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEP 485 Query: 541 CLPGPPGLPCPVSPLGPAGP-ALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT 599 GP G+ P+ P G G + PG GPPGP G G PG G PG DG PG Sbjct: 486 ---GPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGS---DGLPGPK 539 Query: 600 GPQGFPGTPGDVGPKGDKGDPG-VGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS---- 654 G QG G G GPKG +GDPG GE G PG +G G PG KL + G Sbjct: 540 GAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRP 599 Query: 655 ---------GFGGDLEALRGPRGFPGPPGPPG------VPGLPGEPGRFG-VNSSDVPGP 698 G G + L GP+G G PG PG VPG G PG+ G V S GP Sbjct: 600 GPPGSIGIRGQPGSM-GLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGP 658 Query: 699 AGLPGVPGREGPPG---FPGLPGPPGPPGR------EGPPGRTGQKGSLGEAGAPGHKGS 749 GL G G +GPPG F GLPGPPGPPG +G PG G G LG G G+ G Sbjct: 659 PGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGE 718 Query: 750 KGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSAD 809 +G PG G GE G+AG GP GP G PGP G PG P G M G G + D Sbjct: 719 RGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGD 778 Query: 810 -------------------------GPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGF 844 GP GP G G KG+PG GL G G G G G Sbjct: 779 RGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGE 838 Query: 845 PGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG----VGQPGLPGPPGPPGPVVYVSEQDG 900 G G G AGPQGP G G +GE G+PG+ G G GL G PGP GP + G Sbjct: 839 NGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGG 898 Query: 901 -SVLSVPGPEGRPGFAGF---PGPAGPKGNLGSKGERGSPGPKGEKGEPGSIF-----SP 951 PG G PG AG PGPAG G G GE G GP G +G+PGS P Sbjct: 899 RGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGP 958 Query: 952 DGGALGPAQKGAKGE---PGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGD 1008 G GP KG GE PG GPPGP G G +G +G PG+ G GM GL G G PG Sbjct: 959 AGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGK 1018 Query: 1009 ASL--GFGMRGMPGP------------PGPPGPPGPPGTPVYDSNVFAESSR--PGPPGL 1052 G +G PGP PGP GP G GTP D V R PGP GL Sbjct: 1019 VGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGL 1078 Query: 1053 PGNQGPPG---PKGAKGEVG---------PPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQ 1100 PG+QG PG P GA G+ G P GPPG+ L +G +GD+GD G Sbjct: 1079 PGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLP---GPQGPRGDKGDHGD 1135 Query: 1101 KGERGEPGGGGFFG-SSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEG 1159 +G+RG+ G GF G LPGPPGP G +G GIPGP G GPPGP GP G Sbjct: 1136 RGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPR-----GPPGPVGP-----SG 1185 Query: 1160 RQGPPGPPGPPGPPSFPGPHRQT--ISVPGPPGPPGPPGPPGTMGASSG 1206 ++G PGP GP GPP G + PG PGPPGPPGPPG + A+ G Sbjct: 1186 KEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALG 1234 Score = 514 bits (1323), Expect = e-145 Identities = 337/780 (43%), Positives = 376/780 (48%), Gaps = 143/780 (18%) Query: 511 GRVKEGGLKGQKGEPGVPGPPGRAGP---PGSPCLPGPPGLPCPVSPLG---PAGPALQT 564 GR+ G GQ+G G+PG PG GP PGS PG PG+ P G P GP Q Sbjct: 345 GRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQR 404 Query: 565 ----VPGPQGPPGPPGR---DGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGP---K 614 PGP G PG PG DGTPG G G PG G PG GP G PG G GP + Sbjct: 405 GETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIR 464 Query: 615 GDKGDPGV----------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALR 664 G GDPGV GE GP G QGP GPPG E R Sbjct: 465 GQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGE---------------------EGKR 503 Query: 665 GPRGFPGPPGPPGVPGLPGEPGRFGVNSSD-VPGPAGLPGV---------PGREGPPGFP 714 GPRG PG GPPG G G PG G SD +PGP G G G +G PG P Sbjct: 504 GPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRP 563 Query: 715 GLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPP 774 G PG PG G G PG G +G LG GAPG G G PG G RG+ G G PGP G Sbjct: 564 GEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSS 623 Query: 775 GPPGPPGPPG-PGLPA--GFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPG--- 828 G PG PG G G+P G +G GP GP GPPGL G +G+ G PG Sbjct: 624 GDPGKPGEAGNAGVPGQRGAPGKDGEVGP--------SGPVGPPGLAGERGEQGPPGPTG 675 Query: 829 ---LPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGV-GQPGLPG 884 LPG G G G PG G+PG G GP GP+G+RG+ GE+G+PG G+ G+ G+ G Sbjct: 676 FQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAG 735 Query: 885 PPGPPGPVVYVSEQDGSVLSVPGPEGRPG---------------FAGFPGPAGPKGNLGS 929 GP GP GS PGP G PG AG PGP G +G +G Sbjct: 736 GHGPDGP-------KGS----PGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGE 784 Query: 930 KGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRG---PPGPYGRPGYKGE-- 984 KG G+ G G +G PG + P G GP G KGEPG RG PPG G PG +GE Sbjct: 785 KGAEGTAGNDGARGLPGPLGPP--GPAGPT--GEKGEPGPRGLVGPPGSRGNPGSRGENG 840 Query: 985 ----IGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPG---PPGPPGPPGTPVYD 1037 +GF G G G G+KGE GEPG G G PGP G PGP GP G P Sbjct: 841 PTGAVGFAGPQGPDGQPGVKGEPGEPGQK----GDAGSPGPQGLAGSPGPHGPNGVPGLK 896 Query: 1038 SNVFAESSRPGPPGLPGNQG---PPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGD 1094 + PG G PG+ G PPGP GA G GP G PG+ L+ + G GD Sbjct: 897 GGRGTQGP-PGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGD 955 Query: 1095 RGDAGQKGERGEPGGGGFFGSSLPGPPGPPGP------RGYPGIPGPKGESIRGQPGPPG 1148 RG AG G G+ G G G PGP GPPGP RG G+PG +GE RG PG PG Sbjct: 956 RGPAGPPGGPGDKGDPGEDGQ--PGPDGPPGPAGTTGQRGIVGMPGQRGE--RGMPGLPG 1011 Query: 1149 PQGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGV 1207 P G PG +G G G GPPGP GPP GP G PGP GP G GT G V Sbjct: 1012 PAGTPGKVGPTGATGDKGPPGPVGPPGSNGP-------VGEPGPEGPAGNDGTPGRDGAV 1064 Score = 504 bits (1299), Expect = e-142 Identities = 343/848 (40%), Positives = 390/848 (45%), Gaps = 130/848 (15%) Query: 455 PAPPPVTTPPLA----GGSSTEDSRSEEVEEQT-----TVASLGAQTLPGSDSVSTWDGS 505 P PP P+ GG +T R + ++ V + + P S Sbjct: 85 PVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRG 144 Query: 506 VRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP-------------- 551 R P GR G +G GEPGVPG PG GPPG P PGP GL P Sbjct: 145 ERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGL 204 Query: 552 ----------VSPLGPAGP-ALQTVPGPQGPPGPPGRDGTPGR---------DGEPGDPG 591 V P+GP GP LQ G GP GPPG G PG +G PG PG Sbjct: 205 GSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPG 264 Query: 592 EDGKPG------------DTGPQGFPGTPGDVGPKGDKGDPGV----GERGPPGPQGPPG 635 EDG+PG G +GFPG PG G KG +G G+ GE G PG +G G Sbjct: 265 EDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAG 324 Query: 636 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 695 P GP G G L GPRG PG G G G PG+ G G+ Sbjct: 325 PTGPM--------------GAMGPL----GPRGMPGERGRLGPQGAPGQRGAHGMPGK-- 364 Query: 696 PGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGP 755 PGP G G+PG G PG PG+ G GP G GP G GQ+G G G G G GA G Sbjct: 365 PGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGT 424 Query: 756 AGARGESGLAGAPGPAGPPGPPGPPGPPGP----------GLPA--GFDDMEGSGGPFWS 803 G G G G+PG +GPPG GPPG PGP G P G +G GP Sbjct: 425 DGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGE 484 Query: 804 TA-RSADGPQGPPGLPGL---KGDPGVPGLPGAKGEVGADGVPGFP---GLPGREGIAGP 856 GP GPPG G +GDPG G PG GE GA G GFP GLPG +G G Sbjct: 485 PGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGE 544 Query: 857 QGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAG 916 +GP G G +G +GDPG+ G+PGLPG G G V +G + GP G PG G Sbjct: 545 RGPVGSSGPKGSQGDPGRP--GEPGLPGARGLTGN-PGVQGPEGKL----GPLGAPGEDG 597 Query: 917 FPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPY 976 PGP G G G G G PGPKG G+PG G A P Q+GA G+ G GP GP Sbjct: 598 RPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKP-GEAGNAGVPGQRGAPGKDGEVGPSGPV 656 Query: 977 GRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVY 1036 G PG GE G G PG G GL G G PG+ G +G+PG PG GP GP G Sbjct: 657 GPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKP-GDQGVPGDPGAVGPLGPRG---- 711 Query: 1037 DSNVFAESSRPGPPGLPGNQ------GPPGPKGAKGEVGPP---GPPGQFPFDFLQLEAE 1087 + E PG GLPG + GP GPKG+ G G P GPPG + A Sbjct: 712 ERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAG 771 Query: 1088 MKGEKGDRGDAGQKGERGEPGGGGFFGSSLP-GPPGPPGPRGYPGIPGPKG----ESIRG 1142 G KGDRG G+KG G G G G P GPPGP GP G G PGP+G RG Sbjct: 772 TPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRG 831 Query: 1143 QPGPPGPQGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGP---PGPPGPPGPP 1198 PG G GP G +G+ G QGP G PG G P PG + PGP G PGP GP Sbjct: 832 NPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPG-QKGDAGSPGPQGLAGSPGPHGPN 890 Query: 1199 GTMGASSG 1206 G G G Sbjct: 891 GVPGLKGG 898 Score = 503 bits (1296), Expect = e-142 Identities = 343/845 (40%), Positives = 388/845 (45%), Gaps = 184/845 (21%) Query: 463 PPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQK 522 PP G E R+ E S GA+ PG+ + GLKG + Sbjct: 259 PPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLP----------------GLKGHR 302 Query: 523 GEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPG 582 G G+ GP G G PGS GP G P+ +GP GP + +PG +G GP G G G Sbjct: 303 GHKGLEGPKGEVGAPGSKGEAGPTG---PMGAMGPLGP--RGMPGERGRLGPQGAPGQRG 357 Query: 583 RDGEPGDPGEDGKPGDTGPQGFPGTPG---DVGPKGDKGDPGV----GERGPPGPQGPPG 635 G PG PG G G G GFPG PG + GP G +G G GE GPPGP G PG Sbjct: 358 AHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPG 417 Query: 636 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSD- 694 PG I +G+ +GP G PG GPPG G PG PG G Sbjct: 418 LPGA---------IGTDGT------PGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQG 462 Query: 695 ---VPGPAGLPGVPGREGPPGFPG---LPGPPGPPGREGP------PGRTGQKGSLGEAG 742 PG G+PG G GP G PG + GP GPPG EG PG G G +GE G Sbjct: 463 IRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERG 522 Query: 743 APGHKG---SKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG-PGLPA-----GFDD 793 APG++G S G PGP GA+GE G G+ GP G G PG PG PG PG G Sbjct: 523 APGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQG 582 Query: 794 MEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKG---------EVGADGVPGF 844 EG GP A DG GPPG G++G PG GLPG KG E G GVPG Sbjct: 583 PEGKLGPLG--APGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQ 640 Query: 845 PGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVL 903 G PG++G GP GP G G GE+G+ G G G GLPGPPGPPG + G Sbjct: 641 RGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPG-------EGGK-- 691 Query: 904 SVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSI--FSPDGGALGPAQK 961 PG +G PG G GP GP+G G+ GERG PG G GE G PDG P Sbjct: 692 --PGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSP--- 746 Query: 962 GAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGP 1021 G G PG GPPG G PG +G G PG G G G KG +G G+ G RG+PGP Sbjct: 747 GPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGND----GARGLPGP 802 Query: 1022 PGPPGPPGPPGTPVYDSNVFAESSRPGPPGL---------PGNQGPPGPKGAKGEVGPPG 1072 GPPGP GP G E PGP GL PG++G GP GA G GP G Sbjct: 803 LGPPGPAGPTG----------EKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQG 852 Query: 1073 PPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLP-------------- 1118 P GQ G KG+ G+ GQKG+ G PG G GS P Sbjct: 853 PDGQ------------PGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRG 900 Query: 1119 --GPPG------------PPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI-GYEGRQGP 1163 GPPG PPGP G PG GP GE G+ GPPG +G PG G G +GP Sbjct: 901 TQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEP--GKEGPPGLRGDPGSHGRVGDRGP 958 Query: 1164 PGPPGPPGPPSFPGPHRQTISVPGPPGPPGP---------------------PGPPGTMG 1202 GPPG PG PG Q PGP GPPGP PG PG G Sbjct: 959 AGPPGGPGDKGDPGEDGQ----PGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAG 1014 Query: 1203 ASSGV 1207 V Sbjct: 1015 TPGKV 1019 Score = 390 bits (1002), Expect = e-108 Identities = 261/638 (40%), Positives = 300/638 (47%), Gaps = 73/638 (11%) Query: 489 GAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGE------------PGVPGPPGRAGP 536 G +PG DG V P G V GL G++GE PG PGPPG G Sbjct: 633 GNAGVPGQRGAPGKDGEVG-PSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGK 691 Query: 537 PGSPCLPGPPGLPCPVSPLGPAG-PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGK 595 PG +PG PG P+ P G G P + PG G PG G G G DG G PG G Sbjct: 692 PGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGT 751 Query: 596 PGDTGPQGFPGTPGD------VGPKGDKGDPGV----------GERGPPGPQGPPGPPGP 639 PGDTGP G G PG+ GPKGD+G G G RG PGP GPPGP GP Sbjct: 752 PGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGP 811 Query: 640 SFRHDK---LTFIDMEGSGFGGDLEALRGPRG---FPGPPGPPGVPGLPGEPGRFGVNS- 692 + + + GS GP G F GP GP G PG+ GEPG G Sbjct: 812 TGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGD 871 Query: 693 SDVPGPAGLPGVPGREGPPGFPGLPG---PPGPPGREGPPGRTGQKGSLGEAGAPGHKGS 749 + PGP GL G PG GP G PGL G GPPG G PG G+ G G AGAPG G Sbjct: 872 AGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGP 931 Query: 750 KGAPG---PAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTAR 806 G PG P G RG+ G G G GP GPPG PG G G +G GP +T + Sbjct: 932 LGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQ 991 Query: 807 SA-------DGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGP 859 G +G PGLPG G PG G GA G+ G G G PG G G GP+GP Sbjct: 992 RGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGP 1051 Query: 860 KGDRGS---------RGEKGDPGKDGV----GQPGLPGPPGPPGPVVYVSEQDGSVLSVP 906 G+ G+ RG++GDPG G+ G PG PGP G PG D Sbjct: 1052 AGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAG--QRGDPGSRGPI 1109 Query: 907 GPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGP-AQKGAKG 965 GP GR G G PGP GP+G+ G G+RG G KG +G G P G GP ++G+ G Sbjct: 1110 GPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLP--GPPGPNGEQGSAG 1167 Query: 966 EPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPP 1025 PG GP GP G G G+ G PG G G G++G GE G G G PGPPGPP Sbjct: 1168 IPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPE----GPPGEPGPPGPP 1223 Query: 1026 GPPGPPGTPVYDSNVFAESSRPGP-PGLPGNQGPPGPK 1062 GPPG + D + S P P P +Q P K Sbjct: 1224 GPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDK 1261 Score = 373 bits (957), Expect = e-103 Identities = 245/586 (41%), Positives = 279/586 (47%), Gaps = 83/586 (14%) Query: 655 GFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFP 714 G G + + G RG PGP GPPG G GE G G PGP G G+ G G PG P Sbjct: 116 GEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGR-----PGPRGPQGIDGEPGVPGQP 170 Query: 715 GLPGPPGPPGREGPPGRT----GQKGSLGEAGAPGHKGS--KGAPGPAGARGESGLAGAP 768 G PGPPG P GP G + Q L E G + G+ GP G RG GL G Sbjct: 171 GAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQ 230 Query: 769 GPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPG 828 G AGP GPPG PG PGP P G + GP+GPPG PG G+PG G Sbjct: 231 GGAGPTGPPGEPGDPGPMGPIG-----------------SRGPEGPPGKPGEDGEPGRNG 273 Query: 829 LPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGP 888 PG G G+ G GFPG PG G+ G +G KG G +GE G PG G + G GP G Sbjct: 274 NPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKG--EAGPTGPMGA 331 Query: 889 PGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSI 948 GP+ GP G PG G GP G G G+ G G PGP G G PGS Sbjct: 332 MGPL--------------GPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSS 377 Query: 949 FSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGD 1008 P P KG G G RGP GP G+ +GE G PG G PG+ G G G PG Sbjct: 378 GFPGN----PGMKGEAGPTGARGPEGPQGQ---RGETGPPGPVGSPGLPGAIGTDGTPGA 430 Query: 1009 ASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR--PGPPGLPGNQGPPGPKGAKG 1066 G G PG GPPG GPPG+P + + R PG PG+PG +G GPKG G Sbjct: 431 K----GPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPG 486 Query: 1067 E---VGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSS-LPGPPG 1122 GP GPPG+ + + +G+ G G G GERG PG GF GS LPGP G Sbjct: 487 PHGIQGPIGPPGE------EGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKG 540 Query: 1123 PPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI----------GYEGRQGP---PGPPGP 1169 G RG G GPKG +G PG PG G PG G EG+ GP PG G Sbjct: 541 AQGERGPVGSSGPKGS--QGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGR 598 Query: 1170 PGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQA 1215 PGPP G Q S+ G PGP G G PG G + + R A Sbjct: 599 PGPPGSIGIRGQPGSM-GLPGPKGSSGDPGKPGEAGNAGVPGQRGA 643 Score = 71.6 bits (174), Expect = 5e-12 Identities = 47/114 (41%), Positives = 55/114 (48%), Gaps = 14/114 (12%) Query: 1107 PGGGGF-FGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPG 1165 PGGG FG G G +G PG+ P IRG+PGP GP G G G +GP G Sbjct: 100 PGGGNTNFGR------GRKGQKGEPGLV-PVVTGIRGRPGPAGPPGSQGP--RGERGPKG 150 Query: 1166 PPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQ 1219 PGP GP G VPG PG PGPPG P G R ++ + A L + Sbjct: 151 RPGPRGPQGIDGEP----GVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDE 200 Score = 33.1 bits (74), Expect = 2.1 Identities = 38/138 (27%), Positives = 49/138 (35%), Gaps = 9/138 (6%) Query: 69 GSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEENIAGVGAEILNVAKGIRSFVQLW 128 G P PGS P G+ PT A P+ P+ G + G+ + Sbjct: 366 GPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPG--AIG 423 Query: 129 NDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGTTLWPS--RGIPSSPGAHTTEAG 186 D P A+ T T GP AGP +P G+T P RG P PG + Sbjct: 424 TDGTPG---AKGPTGSPGTS-GPPGSAGPPGSPGPQGST-GPQGIRGQPGDPGVPGFKGE 478 Query: 187 TLPAPTPSPPSLGRPWAP 204 P P P + P P Sbjct: 479 AGPKGEPGPHGIQGPIGP 496 Score = 32.3 bits (72), Expect = 3.6 Identities = 48/176 (27%), Positives = 53/176 (30%), Gaps = 16/176 (9%) Query: 46 PEPQGPL-------PVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAE 98 P P GPL P D +H R G PA PG P + EDGQ P Sbjct: 926 PGPAGPLGEPGKEGPPGLRGDPGSH--GRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPP 983 Query: 99 SPDAPEENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPS 158 P VG +G+ PVGP GP Sbjct: 984 GPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPV 1043 Query: 159 STPQENGTTLWPSRGIPSSPGAHTTEAGTL--PAPTPSPPSLGRPWAPLTGPSVPP 212 P G + G P GA E G P P P S G P P GP P Sbjct: 1044 GEPGPEGPA--GNDGTPGRDGA-VGERGDRGDPGPAGLPGSQGAPGTP--GPVGAP 1094 >gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo sapiens] Length = 1650 Score = 524 bits (1350), Expect = e-148 Identities = 393/1062 (37%), Positives = 482/1062 (45%), Gaps = 186/1062 (17%) Query: 246 LAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIR--PATEGPGVLFAITDSAQAMVLLGV 303 +AY A R FP F +DFSLL +R P + P + SAQ + LG+ Sbjct: 58 VAYRVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLY---SAQGVRQLGL 114 Query: 304 KLSGVQDGHQDISLLYTEP-GAGQTHTAASFR-LPAFVGQWTHLALSVAGGFVALYVDCE 361 +L + + LY + G Q + FR L G+W +A++V G V L VDC+ Sbjct: 115 ELG------RPVRFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCK 168 Query: 362 EFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEG 421 + PL RS+R + G +F A+ D + F+G + EL + Q + C +E Sbjct: 169 KRVTRPLPRSARPVLDTHGVIIFGARI--LDEEVFEGDVQELAIVPGVQAAYESCEQKE- 225 Query: 422 DDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEE 481 L E G +P+ P P S +++E + Sbjct: 226 --------------------LECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQS 265 Query: 482 QTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGV-------PGPPG 532 Q PG + + S+ P G GLKG+KGEP V GPPG Sbjct: 266 QDPT--------PGEEE-EILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPG 316 Query: 533 RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQT-VPGPQGPPGPPG-------RDGTPGRD 584 GP G PG G P PV G GP + +PG G PGPPG R G+ G D Sbjct: 317 PEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGD 376 Query: 585 GEP---------------------GDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVG 623 P G PG G G GP G PG+PG G GD +G Sbjct: 377 KGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGD-----LG 431 Query: 624 ERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS-GFGGDLEALRGPRGFPGPPGPPG----- 677 +GP GPQG GPPG + R + +G+ G GD ++G RGF G PG PG Sbjct: 432 PQGPRGPQGLTGPPGKAGRRGRA---GADGARGMPGD-PGVKGDRGFDGLPGLPGEKGHR 487 Query: 678 ----VPGLPGEPGRFGVNSSDVP-GPAGLPGVPGREG---PPGFPGLPGPPGPPGREGPP 729 GLPG PG G D GP GLPG G G P G PG+PGPPG G +GP Sbjct: 488 GDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQ 547 Query: 730 GRTGQKGSLGEAGAPGHKGS---KGAPGPAGA---RGESGLAGAPGPAGPPGPPGPPGPP 783 G G G GE G PG +G+ +G PGP GA GE G G PG G PG GPPG P Sbjct: 548 GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP 607 Query: 784 GPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPG 843 G P G +G GP GP G PG G+KG G+ GL G KGE G DG PG Sbjct: 608 GKEGPPGTKGNQGPSGP--------QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPG 659 Query: 844 FPG------------LPGREGIAGPQGPKGDRGSRGEKGDPG----KDGVGQPGLPGPPG 887 F G +PG G GP+GPKG G G+ G PG K +G PGLPG PG Sbjct: 660 FKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPG 719 Query: 888 PPGPVVYVSEQDGSV--LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEP 945 GP GS+ PG G G G G +GP+G G G RG GP+G G+ Sbjct: 720 RQGP-------KGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKS 772 Query: 946 GSIFSPDG-------GALG-PAQKGAKGEPGFRGPPGPYGR------PGYKGEIGFPGRP 991 G+ + G G G P +G G PG +GPPGP G+ PG +GE+GF G+ Sbjct: 773 GAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKT 832 Query: 992 GRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPG 1051 G PG G+ G +G G+ G RG PGPPGPPG G PGT + PGPPG Sbjct: 833 GPPGPPGVVGPQGAAGETG-PMGERGHPGPPGPPGEQGLPGTAGKEGT----KGDPGPPG 887 Query: 1052 LPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGG 1111 PG GP G +G GE G PG G +G G G AG GERG G GG Sbjct: 888 APGKDGPAGLRGFPGERGLPGTAGGPGLK------GNEGPSGPPGPAGSPGERGAAGSGG 941 Query: 1112 FFGS-SLPGPPGPPGPRGYPGIPGPKG-------ESIRGQPGPPGPQGPPGI-GYEGRQG 1162 G PGP GPPG G G+PG KG + ++G G PGP GPPG+ G +G +G Sbjct: 942 PIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 1001 Query: 1163 PPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGAS 1204 G PG G G H GPPGPPGP GP G GA+ Sbjct: 1002 EVGDPGQKGTKGNKGEH-------GPPGPPGPIGPVGQPGAA 1036 Score = 523 bits (1346), Expect = e-148 Identities = 358/865 (41%), Positives = 397/865 (45%), Gaps = 193/865 (22%) Query: 489 GAQTLPGSDSVSTWDGSVRTPG--GRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPP 546 GAQ LPG PG G + G G +G PG GP G GP G P +PGPP Sbjct: 491 GAQGLPGP------------PGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPP 538 Query: 547 GLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPG 606 G+ P GP G GPQG PGPPG+ GTPG G PG G G G+ GPQG PG Sbjct: 539 GVRGMDGPQGPKGSL-----GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPG 593 Query: 607 TPGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS----- 654 PG G G G PG G +GP GPQGP G PGP ++G Sbjct: 594 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 653 Query: 655 -----GFGGDL-----------------EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNS 692 GF GD+ + GP+G GP G PG PGL GE G+ GV Sbjct: 654 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGV-- 711 Query: 693 SDVPGPAGLPGVPGREGP------PGFPG---------LPGPPGPPGREGPPGRTGQKGS 737 GLPG PGR+GP PGFPG L G GP G GP G GQ+G Sbjct: 712 ------PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGP 765 Query: 738 LGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGLPA---- 789 G G G KG+ G GP G GE GL G GP G PGP GPPGPPG PG P Sbjct: 766 RGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGE 825 Query: 790 -GFDDMEGSGGPFWSTA-------------RSADGPQGPPGLPGL---------KGDPGV 826 GF G GP R GP GPPG GL KGDPG Sbjct: 826 VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGP 885 Query: 827 PGLPGAKGEVGADGVPGFPGLPGR------EGIAGPQGPKGDRGSRGEKGDPGKDG-VGQ 879 PG PG G G G PG GLPG +G GP GP G GS GE+G G G +G Sbjct: 886 PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGP 945 Query: 880 PGLPGPPGPPGPVVY--VSEQDGSVLSVPGPEGRPGF---AGFPGPAGP---------KG 925 PG PGP GPPG V + G + GP GR G G PGPAGP KG Sbjct: 946 PGRPGPQGPPGAAGEKGVPGEKGPI----GPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 1001 Query: 926 NLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEI 985 +G G++G+ G KGE G PG P G P GA GEPG RGP G +G G +G Sbjct: 1002 EVGDPGQKGTKGNKGEHGPPGPP-GPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1060 Query: 986 GFPGRPGRPGMNGL---KGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFA 1042 GF G PG G+ GL GEKGE GD G G PGPPGP GP GP G Sbjct: 1061 GFNGPPGPIGLQGLPGPSGEKGETGDV----GPMGPPGPPGPRGPAGPNGA--------- 1107 Query: 1043 ESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKG 1102 GPPG GN GPPG KG GE G PG +Q E +KG +G+RG+ G+ G Sbjct: 1108 -DGPQGPPGGVGNLGPPGEKGEPGESGSPG---------IQGEPGVKGPRGERGEKGESG 1157 Query: 1103 ERGEPGGGGFFG-SSLPGPPGPPGPRGYPGIPGPKGES----------IRGQPGPPGPQG 1151 + GEPG G G + GP G PGP G+PG PGP GE RG+ G PG G Sbjct: 1158 QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG 1217 Query: 1152 PPGIGYEGRQGPPGPPGPPGPPSFPGPHRQ-----------TISVPG------PPGPPGP 1194 PG G GPPGP G GP PG + I PG P GP G Sbjct: 1218 SPGP--TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1275 Query: 1195 PGPPGTMGASSGV----RLWATRQA 1215 PGP G G V R AT QA Sbjct: 1276 PGPDGLRGLPGSVGQQGRPGATGQA 1300 Score = 432 bits (1112), Expect = e-121 Identities = 306/763 (40%), Positives = 350/763 (45%), Gaps = 146/763 (19%) Query: 489 GAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGL 548 GA G+ S DG PG R GL G +G G PGP G GPPG LPG PG Sbjct: 767 GATGKSGAKGTSGGDGPHGPPGER----GLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQ 822 Query: 549 ------------PCPVSPLGPAGPALQTVP----GPQGPPGPPGRDGTPG---RDGEPGD 589 P P +GP G A +T P G GPPGPPG G PG ++G GD Sbjct: 823 RGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD 882 Query: 590 PGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTF 648 PG G PG GP G G PG+ G G G PG+ G GP GP GP G PG Sbjct: 883 PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG---------- 932 Query: 649 IDMEGSGFGGDLEALRGPRGFPGPPGPPGVPG---LPGEPGRFGVNSSD-------VPGP 698 + +G GG + GP G PGP GPPG G +PGE G G D +PGP Sbjct: 933 -ERGAAGSGGPI----GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGP 987 Query: 699 AGLPGV------------PGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGH 746 AG PGV PG++G G G GPPGPPG GP G+ G G+ GE GA G Sbjct: 988 AGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGP 1047 Query: 747 KGSKGAPGPAGARGESG------LAGAPGPAGPPG------PPGPPGPPGPGLPAGFDDM 794 +G GA G G RG +G L G PGP+G G P GPPGPPGP PAG + Sbjct: 1048 QGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGA 1107 Query: 795 EGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIA 854 +G GP GP G G PG G PG+ G PG KG G G G G PG G Sbjct: 1108 DGPQGPPGGVGNL--GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1165 Query: 855 GPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGF 914 GP+GP GD G KG+PG VG PG PGPPG GP QDG+ G +G PG Sbjct: 1166 GPKGPTGDDGP---KGNPGP--VGFPGDPGPPGEGGP----RGQDGAK-GDRGEDGEPGQ 1215 Query: 915 AGFPGPAG---PKGNLGSKGERGSPGP------KGEKGEPGSIFSPDG----GALGPAQK 961 G PGP G P G LG +G GSPG KG KG+PG+I +P G GPA K Sbjct: 1216 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1275 Query: 962 -------------------GAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGE 1002 GA G+ G GP GP G PG +G+ G G G PG+ GL G Sbjct: 1276 PGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGP 1335 Query: 1003 KGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPK 1062 GE G+ G RG+PGP G PG G G P + GPPGLPG GP G K Sbjct: 1336 PGEQGEK----GDRGLPGPQGSPGQKGEMGIPGASGPI----GPGGPPGLPGPAGPKGAK 1387 Query: 1063 GAKGEVGP------------PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGG 1110 GA G GP PGPPG+ L ++ K + G + + P GG Sbjct: 1388 GATGPGGPKGEKGVQGPPGHPGPPGEV-IQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGG 1446 Query: 1111 GFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPP 1153 PG PG G G E I P G Q P Sbjct: 1447 A------PGSPG--GLEEIFGSLDSLREEIEQMRRPTGTQDSP 1481 Score = 380 bits (975), Expect = e-105 Identities = 264/644 (40%), Positives = 293/644 (45%), Gaps = 111/644 (17%) Query: 443 REETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTW 502 R E G K P PP V P A G E E G Q LPG+ Sbjct: 823 RGEVGFQGKTGPPGPPGVVGPQGAAG---ETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 879 Query: 503 DGSVRTPGGRVKEG-----------GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP 551 G PG K+G GL G G PG+ G G +GPPG PG G Sbjct: 880 KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 939 Query: 552 VSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG---PQGFPGTP 608 P+GP G PGPQGPPG G G PG G G G DG G G P G PG Sbjct: 940 GGPIGPPGR-----PGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA 994 Query: 609 GDVGPKGDKGDPGV-------GERGPPGPQGPPGP---PGPSFRHDKLTFIDMEGS-GFG 657 G+ G KG+ GDPG GE GPPGP GP GP PG + + +G G Sbjct: 995 GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK 1054 Query: 658 GDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLP 717 GD G RGF GPPGP G+ GLPG G G + DV GP G PG PG GP G G Sbjct: 1055 GD----EGTRGFNGPPGPIGLQGLPGPSGEKG-ETGDV-GPMGPPGPPGPRGPAGPNGAD 1108 Query: 718 GPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPP 777 GP GPPG G G G+KG GE+G+PG +G G GP G RGE G +G PG GPPGP Sbjct: 1109 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK 1168 Query: 778 GP------------------PGPPGPGLPAGFDDMEGSGG----PFWSTARSADGPQGPP 815 GP PGPPG G P G D +G G P + G GPP Sbjct: 1169 GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPP 1228 Query: 816 GLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKD 875 G G +G G PG G +G GA G PG G PG+ G GP GP G G G +G PG Sbjct: 1229 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1288 Query: 876 GV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERG 934 G G+PG G GPPGPV GP G PG G G G KG+ G G G Sbjct: 1289 GQQGRPGATGQAGPPGPV--------------GPPGLPGLRGDAGAKGEKGHPGLIGLIG 1334 Query: 935 SPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGP---------PGPYGRPGYKGEI 985 PG +GEKG+ G + P G P QKG G PG GP PGP G G KG Sbjct: 1335 PPGEQGEKGDRG-LPGPQGS---PGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGAT 1390 Query: 986 GFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPG 1029 G PG P KGEK G+ GPPG PGPPG Sbjct: 1391 G-PGGP--------KGEK-------------GVQGPPGHPGPPG 1412 Score = 35.8 bits (81), Expect = 0.32 Identities = 64/245 (26%), Positives = 73/245 (29%), Gaps = 68/245 (27%) Query: 47 EPQGPLPVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEEN 106 EP P P PT D G+ P PG P PP E GQD D Sbjct: 1161 EPGPPGPKGPTGDDGP-----KGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQ 1215 Query: 107 IAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGT 166 G PT P GPL GP+ +P G Sbjct: 1216 PGSPG---------------------PTGE---------NGPPGPLGKRGPAGSPGSEGR 1245 Query: 167 TLWPSRGIPSSPGA-----HTTEAGTL-PAPTPSPPSL----------GRPWAP-LTGPS 209 +G PGA T G PA P P L GRP A GP Sbjct: 1246 Q--GGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPP 1303 Query: 210 VP--PPSSERISEEVGLLQLLGDP-------PPQQVTQTDDPDVGLAYVFGPDANSGQVA 260 P PP + + G G P PP + Q + D GL GP + GQ Sbjct: 1304 GPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGE--QGEKGDRGLP---GPQGSPGQKG 1358 Query: 261 RYHFP 265 P Sbjct: 1359 EMGIP 1363 >gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] Length = 1669 Score = 523 bits (1347), Expect = e-148 Identities = 358/878 (40%), Positives = 414/878 (47%), Gaps = 159/878 (18%) Query: 504 GSVRTPGGRVKEGGLKGQKGEPG----VPGPPGRAGPPGSPCLPGP------------PG 547 G PGG G L G KGEPG +PGPPG G PGSP PGP PG Sbjct: 618 GQAGFPGGPGSPG-LPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPG 676 Query: 548 LPCPVSPLG--------PAGP-ALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGD 598 LP +G P GP + +PG GPPG PGR G G G PG G+ G+PG Sbjct: 677 LPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGV 736 Query: 599 -----TGPQGFPGTPGDVGPKGDKGDPGV----GERGPPGPQGPPGPPGPSFRHDKLTFI 649 G G PG PG G KG G PGV G GPPG QG G PGP + Sbjct: 737 GLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSP 796 Query: 650 DMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGP----------- 698 + G G G RGP G GPPG G PG+ GE G G D+PGP Sbjct: 797 GVPGIGPPG----ARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPG 852 Query: 699 ----AGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPG 754 +GLPG+PG++G PG PG PG G G G PG+ G G +G G PG KG G PG Sbjct: 853 ITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPG 912 Query: 755 PAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGS-------------GGPF 801 +G RG+ GL G G G PG PG G G +G G P Sbjct: 913 SSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPG 972 Query: 802 WSTARSADGPQGPPGLPGLKGDPGV------PGLPGAKGEVGADGVPGFPGLPGREGIAG 855 DG G PG PG KGDPG+ PGLPG KG VG G+PG PG G GI G Sbjct: 973 TPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPG 1032 Query: 856 PQGP---KGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSE-----QDGSVLSVPG 907 PQG GD+G++GEKG G G+G PGL G G G + + GS+ +PG Sbjct: 1033 PQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSI-GIPG 1091 Query: 908 PEGRPGFAGFPGPAGPKGNLGSKGERGS---------PGPKGEKGEPGSIFSPDG--GAL 956 G PG G PG G G+ G GE+G PG KGE G PG+ P G G Sbjct: 1092 MPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTP-GPTGPAGQK 1150 Query: 957 G-------PAQKGAKGEP-----GFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEK- 1003 G P G KGEP GF G PG G G KGE+GFPG G PG+ G KGE+ Sbjct: 1151 GEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQG 1210 Query: 1004 --------------GEPGDASLG----FGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESS 1045 G PG A+ G G +G PG PG PGP GPPG P D V + Sbjct: 1211 FMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGID-GVKGDKG 1269 Query: 1046 RPGPPGLPGNQGP---------------PGPKGAKGEVGPPGPPG-QFPFDFLQLEAEMK 1089 PG PG PG GP PG G+KG++GPPG PG Q P L+ +K Sbjct: 1270 NPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQG-IK 1328 Query: 1090 GEKGDRGDAGQKGERGEPGGGGFFG-----SSLPGPPGPPGPRGYPGIPGPKG-ESIRGQ 1143 G++GD+G G KG G PG G + LPGP GPPG +G G+PGPKG + + G Sbjct: 1329 GDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGL 1388 Query: 1144 PGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1202 G PGP G PG G G++G GP GP GP FPGP PGP G PG GPPGT Sbjct: 1389 VGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGP-------PGPDGLPGSMGPPGTPS 1441 Query: 1203 ASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVR 1240 G TR + + P G I LYV+ Sbjct: 1442 VDHG--FLVTRHSQTIDDPQCPSGTKILYHGYSLLYVQ 1477 Score = 491 bits (1264), Expect = e-138 Identities = 340/851 (39%), Positives = 385/851 (45%), Gaps = 177/851 (20%) Query: 489 GAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGS---PCLPGP 545 G + LPG V + G ++ P G G KG GEPG+PG G GPPG+ P PG Sbjct: 49 GERGLPGLQGVIGFPG-MQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGL 107 Query: 546 PGLPCPVSPLGPAG-PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT----- 599 PG+P P GP G P G +GP GPPG G G G PG PG G PG+ Sbjct: 108 PGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVP 167 Query: 600 -----GPQGFPGTPGDVGPKGDKGDPGV----GERGPPGPQGPPGPPGPSFRHDKLTFID 650 G +GFPG PG GP G G G G GPPGP GPPGPPG Sbjct: 168 GMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPG------------ 215 Query: 651 MEGSGFGGDLEALRGPRGFPGPPGPPGVPGL--------------------PGEPGRFGV 690 E G + +G +G G GPPGVPG PG G GV Sbjct: 216 -EKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGV 274 Query: 691 NSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSK 750 PG G G PG++G G G PG PG PG G GR G +G GEAG PG G Sbjct: 275 GEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIV 334 Query: 751 GAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGLPA-------GFDDMEGSGG 799 GP G +GE G G PGP G PGP G PG PG PGLP GF G G Sbjct: 335 IGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKG 394 Query: 800 PFWSTARSADGPQGPPGLPGLKGDPGVPGLPG--------AKGEVGADGVPGFPGLPGRE 851 S GP G GLPG G PG PG PG G G G PG PG PG Sbjct: 395 DRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFI 454 Query: 852 GIAGPQGPKGD----------RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDG 900 G G +G KG+ RG G +G PG+ G GQPG G G PG +DG Sbjct: 455 GEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPG-------RDG 507 Query: 901 SVLSVPGPEGRPGF-------------------------AGFPGPAGPKGNLGSKGERGS 935 V VPGP+G PG GFPG G G GS G G Sbjct: 508 -VAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGH 566 Query: 936 PGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGY--------KGEIGF 987 PG G KG PGS+ G GP G G PG RG GP G PGY KG+ GF Sbjct: 567 PGLPGPKGSPGSVGLK--GERGP--PGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGF 622 Query: 988 PGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRP 1047 PG PG PG+ G KGE G+ G G+PG PG PGP G G P P Sbjct: 623 PGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFP----------GTP 672 Query: 1048 GPPGLPGNQ-----------GPPGPKGA---KGEVGPPGPPGQFPFDFLQLEAEMKGEKG 1093 G PGLPG + GPPGPKG G++GPPG PG+ F+ L ++G+KG Sbjct: 673 GRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKG 732 Query: 1094 DRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKG-------ESIRGQPGP 1146 + G G G +G PG G +PG PG G G PG+PG G + IRG+PGP Sbjct: 733 EPG-VGLPGLKGLPGLPG-----IPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGP 786 Query: 1147 P------GPQGPPGIGYEGRQGPPGPPGPP---GPPSFPG----PHRQTISVPGPPGPPG 1193 P G G PGIG G +GPPG GPP GPP G P + +PGP G G Sbjct: 787 PGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKG 846 Query: 1194 PPGPPGTMGAS 1204 G PG G S Sbjct: 847 AQGLPGITGQS 857 Score = 446 bits (1148), Expect = e-125 Identities = 313/767 (40%), Positives = 353/767 (46%), Gaps = 160/767 (20%) Query: 565 VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDV---GPKGDKGDPG 621 V G +G G PG G G G G G G PG G G PG PG GP G G PG Sbjct: 44 VKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPG 103 Query: 622 -VGERGPPGPQGPPGPPG-PSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVP 679 G G PG GPPGPPG P K G G L G GF G PGPPG+P Sbjct: 104 NPGLPGIPGQDGPPGPPGIPGCNGTK---------GERGPL-GPPGLPGFAGNPGPPGLP 153 Query: 680 GLPGEPGRF--GVNSSDVPGPAGLPGVPGREGPPGFPGL---------PGPPGPPGREGP 728 G+ G+PG V + G G PG+PG GPPG PGL GPPGPPG GP Sbjct: 154 GMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGP 213 Query: 729 PGRTGQ-----------KGSLGEAGAPG--------HKGSKGAPGPAGARGESGLAGAP- 768 PG GQ KG G +G PG KG G G +GE G G P Sbjct: 214 PGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPG 273 Query: 769 -GPAGPPGPPGPPGPPG----------PGLPA--GFDDMEGSGGPFWSTARSADGPQGPP 815 G G PG PGP G PG PG P G+ + G GP + GP GPP Sbjct: 274 VGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGP--QGEKGEAGPPGPP 331 Query: 816 GLP------GLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREG--IAGPQGPKGDRGSRG 867 G+ G KG+ G PG PG +GE G G PG PG PG G + G G G G RG Sbjct: 332 GIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERG 391 Query: 868 EKGDPGKDGV------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGP---------EGRP 912 EKGD G G G+ GLPGPPG PGP +G V PGP G+P Sbjct: 392 EKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQP 451 Query: 913 GFAGF----------------------PGPAGPKGNL------GSKGERGSPGPKGEKGE 944 GF G PGP GP G + G+KG+RG PG G G Sbjct: 452 GFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGV 511 Query: 945 PGSIFSP----DGGALG-PAQ-------KGAKGEPGFRGPPGPYGR---PGYKGEIGFPG 989 PG +P GA G P + KG KG+PGF G PG GR PG G G PG Sbjct: 512 PGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPG 571 Query: 990 RPGRPGMNGLKGEKGEPGDASLGF-GMRGMPGPPGPP--GPPGPPGTPVYDSNVFAESSR 1046 G PG GLKGE+G PG +GF G RG GPPGPP GP GP G + + Sbjct: 572 PKGSPGSVGLKGERGPPG--GVGFPGSRGDTGPPGPPGYGPAGPIG----------DKGQ 619 Query: 1047 PGPPGLPGNQGPPGPKGAKGEVGP-PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERG 1105 G PG PG+ G PGPKG G++ P PGPPG + L G +GDRG G G G Sbjct: 620 AGFPGGPGSPGLPGPKGEPGKIVPLPGPPGA---EGLPGSPGFPGPQGDRGFPGTPGRPG 676 Query: 1106 EPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKG----------ESIRGQPGPPGPQGPPGI 1155 PG G G G PGPPGP+G G+PG G + G PG G +G PG+ Sbjct: 677 LPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGV 736 Query: 1156 GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1202 G G +G PG PG PG P G +I VPG PG G GPPG G Sbjct: 737 GLPGLKGLPGLPGIPGTPGEKG----SIGVPGVPGEHGAIGPPGLQG 779 Score = 324 bits (830), Expect = 5e-88 Identities = 232/590 (39%), Positives = 259/590 (43%), Gaps = 156/590 (26%) Query: 739 GEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG-PGLPAGFDDMEGS 797 G+ G KG KG G G +G G G GP GP GPPG G G PGLP +G+ Sbjct: 37 GKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPG----TKGT 92 Query: 798 GGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQ 857 GP A G G PG+PG G PG PG+PG G G G G PGLPG G GP Sbjct: 93 RGP--PGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPP 150 Query: 858 GPKGDRGSRGE----------KGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPG 907 G G +G GE KG+ G G+ PG PGPPG PG + G Sbjct: 151 GLPGMKGDPGEILGHVPGMLLKGERGFPGI--PGTPGPPGLPG--------------LQG 194 Query: 908 PEGRPGFAGFPGPAGPKGNLGSKGERGSP--GPKGEKGEPGSIFSPDGGALGPAQ----- 960 P G PGF G PGP GP G G KG+ G GPKG+KG+ G P G G AQ Sbjct: 195 PVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPP--GVPGQAQVQEKG 252 Query: 961 -------KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPG-DASLG 1012 KG KGEPGF+G PG G KGE G PG G+PG +G KGEKG PG G Sbjct: 253 DFATKGEKGQKGEPGFQGMPGV----GEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPG 308 Query: 1013 F-GMRGMPGPPGPPGPPGPPGTP--VYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVG 1069 + G+ G GP G G GPPG P V + E G PG PG +G PGPKG G G Sbjct: 309 YPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPG 368 Query: 1070 PPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGP------PGP 1123 PGPPG P G G G GERGE G GF G+SLPGP PGP Sbjct: 369 QPGPPG-LPVP------------GQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGP 415 Query: 1124 PGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI-----------------------GYEGR 1160 PG G PG PG + QPGPPG QGPPGI +G Sbjct: 416 PGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGY 475 Query: 1161 QGPPGPPGPPGPPSFPG----------PHRQTIS-VPGPPGPPG---------------- 1193 +GPPGP GPPG FPG P R ++ VPGP G PG Sbjct: 476 RGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYF 535 Query: 1194 ------------------------------PPGPPGTMGASSGVRLWATR 1213 PG PG G+ V L R Sbjct: 536 DLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGER 585 Score = 298 bits (762), Expect = 3e-80 Identities = 194/479 (40%), Positives = 222/479 (46%), Gaps = 87/479 (18%) Query: 424 SDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRS--EEVEE 481 S G GD G+ + E G A PP + P L G + E Sbjct: 1036 SPGLPGDKGA---------KGEKGQA------GPPGIGIPGLRGEKGDQGIAGFPGSPGE 1080 Query: 482 QTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPC 541 + S+G +PGS + GSV PG GL G+KG+ G+PG G G G Sbjct: 1081 KGEKGSIGIPGMPGSPGLKGSPGSVGYPG----SPGLPGEKGDKGLPGLDGIPGVKGEAG 1136 Query: 542 LPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGE--PGDPGEDGKPGDT 599 LPG PG P GPAG + PG G PG G G PG G PG PG G G Sbjct: 1137 LPGTPG------PTGPAGQ--KGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSK 1188 Query: 600 GPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGD 659 G GFPG G G G KG+ G GPPGPQG PG P G Sbjct: 1189 GEVGFPGLAGSPGIPGSKGEQGF--MGPPGPQGQPGLP-------------------GSP 1227 Query: 660 LEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGP 719 A GP+G GP G PG+PGLPG G PG G+ GV G +G PG+PG PG Sbjct: 1228 GHATEGPKGDRGPQGQPGLPGLPGPMG--------PPGLPGIDGVKGDKGNPGWPGAPGV 1279 Query: 720 PGP---------PGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGP 770 PGP PG G PG TG KG +G G PG +G KG PG G +G+ G G PG Sbjct: 1280 PGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGA 1339 Query: 771 AGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLP 830 G PGPPGPPGP +D ++G G GP+GPPGL GL+G PG G Sbjct: 1340 KGLPGPPGPPGP--------YDIIKGEPG--------LPGPEGPPGLKGLQGLPGPKGQQ 1383 Query: 831 GAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPP 889 G G VG G PG PG G G G GP G G RG G PG DG+ PG GPPG P Sbjct: 1384 GVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGL--PGSMGPPGTP 1440 Score = 76.3 bits (186), Expect = 2e-13 Identities = 61/199 (30%), Positives = 73/199 (36%), Gaps = 47/199 (23%) Query: 425 DGASGDSGSGLGDARELLREETGAALKPRLPAP---PPVTTPPLAGGSSTEDSRSEEVEE 481 DG GD G+ G P +P P P P GGS ++ Sbjct: 1262 DGVKGDKGN------------PGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGP 1309 Query: 482 QTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGG---------LKGQKGEPGVPGPPG 532 G + LPG + G PG + G +KG+ G PG GPPG Sbjct: 1310 PGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPG 1369 Query: 533 R------------------AGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGP 574 G PG P +PG G P +GPAGP GP+G PGP Sbjct: 1370 LKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPT-----GPRGFPGP 1424 Query: 575 PGRDGTPGRDGEPGDPGED 593 PG DG PG G PG P D Sbjct: 1425 PGPDGLPGSMGPPGTPSVD 1443 >gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo sapiens] Length = 1736 Score = 523 bits (1346), Expect = e-148 Identities = 358/865 (41%), Positives = 397/865 (45%), Gaps = 193/865 (22%) Query: 489 GAQTLPGSDSVSTWDGSVRTPG--GRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPP 546 GAQ LPG PG G + G G +G PG GP G GP G P +PGPP Sbjct: 577 GAQGLPGP------------PGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPP 624 Query: 547 GLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPG 606 G+ P GP G GPQG PGPPG+ GTPG G PG G G G+ GPQG PG Sbjct: 625 GVRGMDGPQGPKGSL-----GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPG 679 Query: 607 TPGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS----- 654 PG G G G PG G +GP GPQGP G PGP ++G Sbjct: 680 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 739 Query: 655 -----GFGGDL-----------------EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNS 692 GF GD+ + GP+G GP G PG PGL GE G+ GV Sbjct: 740 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGV-- 797 Query: 693 SDVPGPAGLPGVPGREGP------PGFPG---------LPGPPGPPGREGPPGRTGQKGS 737 GLPG PGR+GP PGFPG L G GP G GP G GQ+G Sbjct: 798 ------PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGP 851 Query: 738 LGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGLPA---- 789 G G G KG+ G GP G GE GL G GP G PGP GPPGPPG PG P Sbjct: 852 RGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGE 911 Query: 790 -GFDDMEGSGGPFWSTA-------------RSADGPQGPPGLPGL---------KGDPGV 826 GF G GP R GP GPPG GL KGDPG Sbjct: 912 VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGP 971 Query: 827 PGLPGAKGEVGADGVPGFPGLPGR------EGIAGPQGPKGDRGSRGEKGDPGKDG-VGQ 879 PG PG G G G PG GLPG +G GP GP G GS GE+G G G +G Sbjct: 972 PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGP 1031 Query: 880 PGLPGPPGPPGPVVY--VSEQDGSVLSVPGPEGRPGF---AGFPGPAGP---------KG 925 PG PGP GPPG V + G + GP GR G G PGPAGP KG Sbjct: 1032 PGRPGPQGPPGAAGEKGVPGEKGPI----GPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 1087 Query: 926 NLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEI 985 +G G++G+ G KGE G PG P G P GA GEPG RGP G +G G +G Sbjct: 1088 EVGDPGQKGTKGNKGEHGPPGPP-GPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1146 Query: 986 GFPGRPGRPGMNGL---KGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFA 1042 GF G PG G+ GL GEKGE GD G G PGPPGP GP GP G Sbjct: 1147 GFNGPPGPIGLQGLPGPSGEKGETGDV----GPMGPPGPPGPRGPAGPNGA--------- 1193 Query: 1043 ESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKG 1102 GPPG GN GPPG KG GE G PG +Q E +KG +G+RG+ G+ G Sbjct: 1194 -DGPQGPPGGVGNLGPPGEKGEPGESGSPG---------IQGEPGVKGPRGERGEKGESG 1243 Query: 1103 ERGEPGGGGFFG-SSLPGPPGPPGPRGYPGIPGPKGES----------IRGQPGPPGPQG 1151 + GEPG G G + GP G PGP G+PG PGP GE RG+ G PG G Sbjct: 1244 QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG 1303 Query: 1152 PPGIGYEGRQGPPGPPGPPGPPSFPGPHRQ-----------TISVPG------PPGPPGP 1194 PG G GPPGP G GP PG + I PG P GP G Sbjct: 1304 SPGP--TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1361 Query: 1195 PGPPGTMGASSGV----RLWATRQA 1215 PGP G G V R AT QA Sbjct: 1362 PGPDGLRGLPGSVGQQGRPGATGQA 1386 Score = 497 bits (1280), Expect = e-140 Identities = 393/1112 (35%), Positives = 481/1112 (43%), Gaps = 199/1112 (17%) Query: 246 LAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIR--PATEGPGVLFAITDSAQAMVLLGV 303 +AY A R FP F +DFSLL +R P + P + SAQ + LG+ Sbjct: 58 VAYRVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLY---SAQGVRQLGL 114 Query: 304 KLSGVQDGHQDISLLYTEP-GAGQTHTAASFR-LPAFVGQWTHLALSVAGGFVALYVDCE 361 +L + + LY + G Q + FR L G+W +A++V G V L VDC+ Sbjct: 115 ELG------RPVRFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCK 168 Query: 362 EFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEG 421 + PL RS+R + G +F A+ D + F+G + EL + Q + C +E Sbjct: 169 KRVTRPLPRSARPVLDTHGVIIFGARI--LDEEVFEGDVQELAIVPGVQAAYESCEQKEL 226 Query: 422 DDSDG-ASGDSGSGLGDARELLREETGAALKPRLPAP-------------PP----VTTP 463 + G A+ +++ +P+ P PP +TT Sbjct: 227 ECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQPTESLYYDYEPPYYDVMTTG 286 Query: 464 PLAGGSSTEDSRSEEVEEQTTVASL-----GAQTLPGSDSVST---WDGSVRTPGGRVK- 514 EE+ E + + L Q P +D +G P G Sbjct: 287 TTPDYQDPTPGEEEEILESSLLPPLEEEQTDLQVPPTADRFQAEEYGEGGTDPPEGPYDY 346 Query: 515 EGGLKGQKGEPGVPGPP-------GRAGPPGSPCLPGPPGLPC----------PVSPLGP 557 G E GP A G L G G P P P GP Sbjct: 347 TYGYGDDYREETELGPALSAETAHSGAAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGP 406 Query: 558 AG----PALQTVPGPQGPP---GPPGRDGTPGRDGEPGDPGED----------------- 593 AG P +Q PGP G P GPPGR G PG DG PG PG Sbjct: 407 AGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPV 466 Query: 594 --------------------GKPGDTGPQGFPGTPGDVGPKGDKGDPG-VGERGPPGPQG 632 G PG G G PG G G G KG+ G +G +GP GPQG Sbjct: 467 VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 526 Query: 633 PPGPPGPSFRHDKLTFIDMEGS-GFGGDLEALRGPRGFPGPPGPP---------GVPGLP 682 GPPG + R + +G+ G GD ++G RGF G PG P G GLP Sbjct: 527 LTGPPGKAGRRGR---AGADGARGMPGD-PGVKGDRGFDGLPGLPGEKGHRGDTGAQGLP 582 Query: 683 GEPGRFGVNSSDVP-GPAGLPGVPGRE---GPPGFPGLPGPPGPPGREGPPGRTGQKGSL 738 G PG G D GP GLPG G GP G PG+PGPPG G +GP G G G Sbjct: 583 GPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQ 642 Query: 739 GEAGAPGHK---GSKGAPGPAGA---RGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFD 792 GE G PG + G++G PGP GA GE G G PG G PG GPPG PG P G Sbjct: 643 GEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTK 702 Query: 793 DMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFP------- 845 +G GP GP G PG G+KG G+ GL G KGE G DG PGF Sbjct: 703 GNQGPSGP--------QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKG 754 Query: 846 -----GLPGREGIAGPQGPKGDRGSRGEKGDPG----KDGVGQPGLPGPPGPPGPVVYVS 896 G+PG G GP+GPKG G G+ G PG K +G PGLPG PG GP Sbjct: 755 DRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGP----- 809 Query: 897 EQDGSV--LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGS------- 947 GS+ PG G G G G +GP+G G G RG GP+G G+ G+ Sbjct: 810 --KGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGD 867 Query: 948 -IFSPDGGALGPAQKGAKGEPGFRGPPGPYGR------PGYKGEIGFPGRPGRPGMNGLK 1000 P G P +G G PG +GPPGP G+ PG +GE+GF G+ G PG G+ Sbjct: 868 GPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVV 927 Query: 1001 GEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPG 1060 G +G G+ G RG PGPPGPPG G PGT + PGPPG PG GP G Sbjct: 928 GPQGAAGETG-PMGERGHPGPPGPPGEQGLPGTAGKEGT----KGDPGPPGAPGKDGPAG 982 Query: 1061 PKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFG-SSLPG 1119 +G GE G PG G +G G G AG GERG G GG G PG Sbjct: 983 LRGFPGERGLPGTAGGPGL------KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPG 1036 Query: 1120 PPGPPGPRGYPGIPGPKG-------ESIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPG 1171 P GPPG G G+PG KG + ++G G PGP GPPG+ G +G +G G PG G Sbjct: 1037 PQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKG 1096 Query: 1172 PPSFPGPHRQTISVPGPPGPPGPPGPPGTMGA 1203 G H PGPPGP GP G PG GA Sbjct: 1097 TKGNKGEH----GPPGPPGPIGPVGQPGAAGA 1124 Score = 491 bits (1264), Expect = e-138 Identities = 341/853 (39%), Positives = 400/853 (46%), Gaps = 131/853 (15%) Query: 419 EEGDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEE 478 E G D D G GD REET L P L A T A + E+ Sbjct: 334 EGGTDPPEGPYDYTYGYGDD---YREET--ELGPALSAE---TAHSGAAAHGPRGLKGEK 385 Query: 479 VEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPG 538 E + + PG + + G + PG + G G G+PG GPPGRAG PG Sbjct: 386 GEPAVLEPGMLVEGPPGPEGPA---GLIGPPGIQ----GNPGPVGDPGERGPPGRAGLPG 438 Query: 539 SPCLPGPPGLPCPV-----SPLGPAGPAL------------QTVPGPQGPPGPPGRDGTP 581 S PGPPG + S G GP + Q +GPPGP G G P Sbjct: 439 SDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRP 498 Query: 582 GRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSF 641 G G+PG PG G+ GD GPQG G G GP G G G G G +G PG PG Sbjct: 499 GPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRG--RAGADGARGMPGDPG--V 554 Query: 642 RHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGL 701 + D+ GF G L L G +G G G G+PG PGE G G + GP GL Sbjct: 555 KGDR---------GFDG-LPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI--GPRGL 602 Query: 702 PGVPGREG---PPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGS---KGAPGP 755 PG G G P G PG+PGPPG G +GP G G G GE G PG +G+ +G PGP Sbjct: 603 PGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGP 662 Query: 756 AGA---RGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQ 812 GA GE G G PG G PG GPPG PG P G +G GP GP Sbjct: 663 QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGP--------QGPL 714 Query: 813 GPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPG------------LPGREGIAGPQGPK 860 G PG G+KG G+ GL G KGE G DG PGF G +PG G GP+GPK Sbjct: 715 GYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPK 774 Query: 861 GDRGSRGEKGDPG----KDGVGQPGLPGPPGPPGPVVYVSEQDGSV--LSVPGPEGRPGF 914 G G G+ G PG K +G PGLPG PG GP GS+ PG G G Sbjct: 775 GRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGP-------KGSLGFPGFPGASGEKGA 827 Query: 915 AGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDG-------GALG-PAQKGAKGE 966 G G +GP+G G G RG GP+G G+ G+ + G G G P +G G Sbjct: 828 RGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGF 887 Query: 967 PGFRGPPGPYGR------PGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPG 1020 PG +GPPGP G+ PG +GE+GF G+ G PG G+ G +G G+ G RG PG Sbjct: 888 PGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG-PMGERGHPG 946 Query: 1021 PPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFD 1080 PPGPPG G PGT + PGPPG PG GP G +G GE G PG G Sbjct: 947 PPGPPGEQGLPGTAGKEGT----KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLK 1002 Query: 1081 FLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIPGPKG-- 1137 +G G G AG GERG G GG G PGP GPPG G G+PG KG Sbjct: 1003 ------GNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPI 1056 Query: 1138 -----ESIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGP 1191 + ++G G PGP GPPG+ G +G +G G PG G G H GPPGP Sbjct: 1057 GPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEH-------GPPGP 1109 Query: 1192 PGPPGPPGTMGAS 1204 PGP GP G GA+ Sbjct: 1110 PGPIGPVGQPGAA 1122 Score = 489 bits (1258), Expect = e-137 Identities = 323/767 (42%), Positives = 366/767 (47%), Gaps = 125/767 (16%) Query: 518 LKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVP----------- 566 L+G G G G PG G PGSP L G G + P GP GP T P Sbjct: 485 LRGPPGPMGYTGRPGPLGQPGSPGLKGESG---DLGPQGPRGPQGLTGPPGKAGRRGRAG 541 Query: 567 --GPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-- 622 G +G PG PG G G DG PG PGE G GDTG QG PG PG+ G +GD G+ G Sbjct: 542 ADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRG 601 Query: 623 -----GERGPPGPQGPPGPPGPSFRHDKLTFIDMEG-SGFGGDLEALRGPRGFPGPPGPP 676 G RG GP+GPPG PGP M+G G G L GP+G PGPPG Sbjct: 602 LPGESGPRGLLGPKGPPGIPGPPGVRG------MDGPQGPKGSL----GPQGEPGPPGQQ 651 Query: 677 GVPG---LPGEPGRFGVNSSDVP-GPAGLPGVPGREGPPGFPGLPGPPGPPGREGP---- 728 G PG LPG G G + P G GLPG+PG +GPPG PG GPPG G +GP Sbjct: 652 GTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQ 711 Query: 729 -----PGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPP 783 PG G KG G G GHKG KG G G +G+ G+ G G G PG G GP Sbjct: 712 GPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPE 771 Query: 784 GPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPG 843 GP +G GP G GPPGL G KG GVPGLPG G G G G Sbjct: 772 GP---------KGRTGP--------TGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLG 814 Query: 844 FPGLPG------------REGIAGPQGPKGDRGSRGEKGDPGKDGV-GQPGLPGPPGPPG 890 FPG PG + G G +GP G RG RG +G GK G G G GP GPPG Sbjct: 815 FPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPG 874 Query: 891 PVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGN---LGSKGERGSPGPKGEKGEPG- 946 +PGP+G GF G GP GP G G G+RG G +G+ G PG Sbjct: 875 E-----------RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP 923 Query: 947 -SIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPG---------M 996 + P G A G +G PG GPPG G PG G+ G G PG PG + Sbjct: 924 PGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGL 983 Query: 997 NGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQ 1056 G GE+G PG A G G++G GP GPPGP G PG + GPPG PG Q Sbjct: 984 RGFPGERGLPGTAG-GPGLKGNEGPSGPPGPAGSPG----ERGAAGSGGPIGPPGRPGPQ 1038 Query: 1057 GPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSS 1116 GPPG G KG G GP G D +Q + G G G AG+ G++GE G G G+ Sbjct: 1039 GPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTK 1098 Query: 1117 ----LPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPG 1171 GPPGPPGP G G PG G G+PG GPQG G G EG +G GPPGP G Sbjct: 1099 GNKGEHGPPGPPGPIGPVGQPGAAGAD--GEPGARGPQGHFGAKGDEGTRGFNGPPGPIG 1156 Query: 1172 PPSFPGPHRQT--------ISVPGPPGP---PGPPGPPGTMGASSGV 1207 PGP + + PGPPGP GP G G G GV Sbjct: 1157 LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGV 1203 Score = 432 bits (1112), Expect = e-121 Identities = 306/763 (40%), Positives = 350/763 (45%), Gaps = 146/763 (19%) Query: 489 GAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGL 548 GA G+ S DG PG R GL G +G G PGP G GPPG LPG PG Sbjct: 853 GATGKSGAKGTSGGDGPHGPPGER----GLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQ 908 Query: 549 ------------PCPVSPLGPAGPALQTVP----GPQGPPGPPGRDGTPG---RDGEPGD 589 P P +GP G A +T P G GPPGPPG G PG ++G GD Sbjct: 909 RGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD 968 Query: 590 PGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTF 648 PG G PG GP G G PG+ G G G PG+ G GP GP GP G PG Sbjct: 969 PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG---------- 1018 Query: 649 IDMEGSGFGGDLEALRGPRGFPGPPGPPGVPG---LPGEPGRFGVNSSD-------VPGP 698 + +G GG + GP G PGP GPPG G +PGE G G D +PGP Sbjct: 1019 -ERGAAGSGGPI----GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGP 1073 Query: 699 AGLPGV------------PGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGH 746 AG PGV PG++G G G GPPGPPG GP G+ G G+ GE GA G Sbjct: 1074 AGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGP 1133 Query: 747 KGSKGAPGPAGARGESG------LAGAPGPAGPPG------PPGPPGPPGPGLPAGFDDM 794 +G GA G G RG +G L G PGP+G G P GPPGPPGP PAG + Sbjct: 1134 QGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGA 1193 Query: 795 EGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIA 854 +G GP GP G G PG G PG+ G PG KG G G G G PG G Sbjct: 1194 DGPQGPPGGVGNL--GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1251 Query: 855 GPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGF 914 GP+GP GD G KG+PG VG PG PGPPG GP QDG+ G +G PG Sbjct: 1252 GPKGPTGDDGP---KGNPGP--VGFPGDPGPPGEGGP----RGQDGAK-GDRGEDGEPGQ 1301 Query: 915 AGFPGPAG---PKGNLGSKGERGSPGP------KGEKGEPGSIFSPDG----GALGPAQK 961 G PGP G P G LG +G GSPG KG KG+PG+I +P G GPA K Sbjct: 1302 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1361 Query: 962 -------------------GAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGE 1002 GA G+ G GP GP G PG +G+ G G G PG+ GL G Sbjct: 1362 PGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGP 1421 Query: 1003 KGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPK 1062 GE G+ G RG+PGP G PG G G P + GPPGLPG GP G K Sbjct: 1422 PGEQGEK----GDRGLPGPQGSPGQKGEMGIPGASGPI----GPGGPPGLPGPAGPKGAK 1473 Query: 1063 GAKGEVGP------------PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGG 1110 GA G GP PGPPG+ L ++ K + G + + P GG Sbjct: 1474 GATGPGGPKGEKGVQGPPGHPGPPGEV-IQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGG 1532 Query: 1111 GFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPP 1153 PG PG G G E I P G Q P Sbjct: 1533 A------PGSPG--GLEEIFGSLDSLREEIEQMRRPTGTQDSP 1567 Score = 380 bits (975), Expect = e-105 Identities = 264/644 (40%), Positives = 293/644 (45%), Gaps = 111/644 (17%) Query: 443 REETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTW 502 R E G K P PP V P A G E E G Q LPG+ Sbjct: 909 RGEVGFQGKTGPPGPPGVVGPQGAAG---ETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 965 Query: 503 DGSVRTPGGRVKEG-----------GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP 551 G PG K+G GL G G PG+ G G +GPPG PG G Sbjct: 966 KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 1025 Query: 552 VSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG---PQGFPGTP 608 P+GP G PGPQGPPG G G PG G G G DG G G P G PG Sbjct: 1026 GGPIGPPGR-----PGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA 1080 Query: 609 GDVGPKGDKGDPGV-------GERGPPGPQGPPGP---PGPSFRHDKLTFIDMEGS-GFG 657 G+ G KG+ GDPG GE GPPGP GP GP PG + + +G G Sbjct: 1081 GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK 1140 Query: 658 GDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLP 717 GD G RGF GPPGP G+ GLPG G G + DV GP G PG PG GP G G Sbjct: 1141 GD----EGTRGFNGPPGPIGLQGLPGPSGEKG-ETGDV-GPMGPPGPPGPRGPAGPNGAD 1194 Query: 718 GPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPP 777 GP GPPG G G G+KG GE+G+PG +G G GP G RGE G +G PG GPPGP Sbjct: 1195 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK 1254 Query: 778 GP------------------PGPPGPGLPAGFDDMEGSGG----PFWSTARSADGPQGPP 815 GP PGPPG G P G D +G G P + G GPP Sbjct: 1255 GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPP 1314 Query: 816 GLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKD 875 G G +G G PG G +G GA G PG G PG+ G GP GP G G G +G PG Sbjct: 1315 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1374 Query: 876 GV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERG 934 G G+PG G GPPGPV GP G PG G G G KG+ G G G Sbjct: 1375 GQQGRPGATGQAGPPGPV--------------GPPGLPGLRGDAGAKGEKGHPGLIGLIG 1420 Query: 935 SPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGP---------PGPYGRPGYKGEI 985 PG +GEKG+ G + P G P QKG G PG GP PGP G G KG Sbjct: 1421 PPGEQGEKGDRG-LPGPQGS---PGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGAT 1476 Query: 986 GFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPG 1029 G PG P KGEK G+ GPPG PGPPG Sbjct: 1477 G-PGGP--------KGEK-------------GVQGPPGHPGPPG 1498 Score = 35.8 bits (81), Expect = 0.32 Identities = 64/245 (26%), Positives = 73/245 (29%), Gaps = 68/245 (27%) Query: 47 EPQGPLPVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEEN 106 EP P P PT D G+ P PG P PP E GQD D Sbjct: 1247 EPGPPGPKGPTGDDGP-----KGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQ 1301 Query: 107 IAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGT 166 G PT P GPL GP+ +P G Sbjct: 1302 PGSPG---------------------PTGE---------NGPPGPLGKRGPAGSPGSEGR 1331 Query: 167 TLWPSRGIPSSPGA-----HTTEAGTL-PAPTPSPPSL----------GRPWAP-LTGPS 209 +G PGA T G PA P P L GRP A GP Sbjct: 1332 Q--GGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPP 1389 Query: 210 VP--PPSSERISEEVGLLQLLGDP-------PPQQVTQTDDPDVGLAYVFGPDANSGQVA 260 P PP + + G G P PP + Q + D GL GP + GQ Sbjct: 1390 GPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGE--QGEKGDRGLP---GPQGSPGQKG 1444 Query: 261 RYHFP 265 P Sbjct: 1445 EMGIP 1449 >gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] Length = 1690 Score = 514 bits (1325), Expect = e-145 Identities = 345/830 (41%), Positives = 398/830 (47%), Gaps = 127/830 (15%) Query: 455 PAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVK 514 P PP PP G + S + + + G DG PG + Sbjct: 529 PGPPGAEGPP---GLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPG-QPG 584 Query: 515 EGGLKGQKGEPGVPGPPG--RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPP 572 G G GE G PGPPG PG PGP G P P+GP G PG +G P Sbjct: 585 SHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHP 644 Query: 573 GPPGRDGTPGRDGEPGDPGEDGK-----PGDTGPQGFPGTPGDVGPKGDKGDPGV----G 623 G PG G G DG G G+ PG GP GF G PG G G +G PG+ G Sbjct: 645 GVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDG 704 Query: 624 ERGPPGPQGP---PGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPG 680 +G PG G PGPPG FR D M GFGG+ + P G PGPPG PGV G Sbjct: 705 HKGRPGTPGTAEIPGPPG--FRGD------MGDPGFGGEKGS--SPVGPPGPPGSPGVNG 754 Query: 681 LPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP------GREGPPGRTGQ 734 G PG PG GL GVPG +GP G PG PG GP G +GP GR G Sbjct: 755 QKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGH 814 Query: 735 KGSLGEAGAPGH---KGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGL 787 G G G PGH +G+ G PG G G G GAPG G PG GPPGP G PGL Sbjct: 815 AGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGL 874 Query: 788 PA-----GFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVP 842 P G + G GPF DG GPPG G +G PG PG PG +G+ GA+G P Sbjct: 875 PGRPGAHGPPGLPGIPGPF-----GDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCP 929 Query: 843 GFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG----VGQPGLPGPPGPPGPVVYVSEQ 898 G G PG +G++G G +G RG++G G PG +G + Q G PG PGPPG + E+ Sbjct: 930 GAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGER 989 Query: 899 DGSVLSVPGPEGR---------PGF----------AGFPGPAGPKGNLGSKGERGSPGPK 939 PG +GR PGF G PGP GP G+ G +G G PG Sbjct: 990 GDK--GTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLP 1047 Query: 940 GEKGEPGSI----FSPDGGALGPAQKGAKGEPGFR-GPPGPYGRPGYKGEIGFPGRPGRP 994 G++GEPGS FS GA GP KG KG+P GPPGP KGE PG PG P Sbjct: 1048 GDQGEPGSPGPPGFSGIDGARGP--KGNKGDPASHFGPPGP------KGE---PGSPGCP 1096 Query: 995 GMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPG 1054 G G GE+G PG G RG PG PGPPG GPPG P + PG G PG Sbjct: 1097 GHFGASGEQGLPGIQ----GPRGSPGRPGPPGSSGPPGCP-------GDHGMPGLRGQPG 1145 Query: 1055 NQGPPGPKGAKGEVGPPGPPG-QFPFDFLQLEA--EMKGEKGDRGDA------------- 1098 G PGP+G +G+ G PGPPG + P L +KG+KG +G + Sbjct: 1146 EMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGI 1205 Query: 1099 -GQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRG-----QPGPPGPQGP 1152 G KGERG+PG G G GPPGP G G PGP G + R PGPPG QGP Sbjct: 1206 PGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGP 1265 Query: 1153 PGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1202 P G +G +G PGPPG PG +PGPPGPPGPPGPPG G Sbjct: 1266 P--GPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKG 1313 Score = 512 bits (1318), Expect = e-144 Identities = 357/877 (40%), Positives = 408/877 (46%), Gaps = 153/877 (17%) Query: 447 GAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSV 506 GA P LP + PP G+ + S + G PG DG Sbjct: 533 GAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHA 592 Query: 507 RTPGGRVKEG----GLKGQKGEPGVPGPPGRAGPPGSPCL--PGPPG------LPCPVSP 554 G G G KG PG GPPG+AGP G P L PGPPG +P Sbjct: 593 GEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGV 652 Query: 555 LGPAGPALQ---------TVPGPQGPPG---PPGRDGTPGRDGEPGDPGEDGKPGDTGPQ 602 GP G Q T PG GPPG PPG G PG G PG G DG G G Sbjct: 653 RGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTP 712 Query: 603 GFPGTPGDVGPKGDKGDPGVG-ERG--PPGPQGPPGPPG----------PSFRHDKLTFI 649 G PG G +GD GDPG G E+G P GP GPPG PG P+F H + Sbjct: 713 GTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGH-----L 767 Query: 650 DMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPG--- 706 G + ++GPRG PG PG G G+PG G G + G AG PGVPG Sbjct: 768 GPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGRE--GHAGFPGVPGPPG 825 Query: 707 ---REGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESG 763 G PG PG PG PG PG G PG GQ G +G G G KG G PG GA G G Sbjct: 826 HSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPG 885 Query: 764 LAGAPGPAGPPGPPGPPGPPGP-GLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKG 822 L G PGP G G PGPPGP GP GLP GF G G A G +G PG G+ G Sbjct: 886 LPGIPGPFGDDGLPGPPGPKGPRGLP-GFPGFPGERGK--PGAEGCPGAKGEPGEKGMSG 942 Query: 823 DPGVPGLPGAKGEVGADG------------VPGFPGLPGREGIAGPQGPKGDRGSRGEKG 870 PG GL GAKG +G G PG PG PG +G G +G KG G +G +G Sbjct: 943 LPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRG 1002 Query: 871 DPGKDGV--------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAG 922 +PG+ G G+ G PGPPGPPGP PG G GF GFPG G Sbjct: 1003 EPGRYGPPGFHRGEPGEKGQPGPPGPPGP--------------PGSTGLRGFIGFPGLPG 1048 Query: 923 PKGNLGSKGERG------SPGPKGEKGEPGSIFSPDG-----GALG-PAQKGAKGE---P 967 +G GS G G + GPKG KG+P S F P G G+ G P GA GE P Sbjct: 1049 DQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLP 1108 Query: 968 GFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGP 1027 G +GP G GRPG G G PG PG GM GL+G+ GE GD G++G PG PGPPG Sbjct: 1109 GIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPR-GLQGDPGIPGPPGI 1167 Query: 1028 PGPPGTPVYDSNVFAESSRPGPPGLPG--NQGPPGP---KGAKGEVGPPGPPGQFPFDFL 1082 GP G+P + + + G G G + GPPGP G KGE G PG PG P Sbjct: 1168 KGPSGSPGLNG-LHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISP---- 1222 Query: 1083 QLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSS---LP--------GPPGPPGPRGYPG 1131 G +G +G G G G PG G G + +P GPPGP GPRG PG Sbjct: 1223 ------PGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPG 1276 Query: 1132 IPGPKGE-----------SIRGQPGPPGPQGPPGI-------GYEGRQGPPGPPGPPGPP 1173 PG G + G PGPPGP GPPG G +G++GP G PGP GP Sbjct: 1277 PPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPH 1336 Query: 1174 SFPGPHRQTISVPGPPG---PPGPPGPPGTMGASSGV 1207 FPGP + +PGPPG P G PGP G G + V Sbjct: 1337 GFPGPPGEK-GLPGPPGRKGPTGLPGPRGEPGPPADV 1372 Score = 491 bits (1265), Expect = e-138 Identities = 352/876 (40%), Positives = 396/876 (45%), Gaps = 176/876 (20%) Query: 486 ASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGS------ 539 A+ G + PG G V PG + G G++G PGVPG PG GP G Sbjct: 607 ATPGGKGFPGPLGPPGKAGPVGPPG--LGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGD 664 Query: 540 --------PCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPG 591 P GPPG P P G GP Q PG G G GR GTPG PG PG Sbjct: 665 TISCNVTYPGRHGPPGFDGPPGPKGFPGP--QGAPGLSGSDGHKGRPGTPGTAEIPGPPG 722 Query: 592 EDGKPGD-----------TGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPS 640 G GD GP G PG+PG G KG GDP G GPPG +G G PG Sbjct: 723 FRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIK 782 Query: 641 FRHDKLTFIDMEG-SGFGGDLEALRGPRG------FPGPPGPPG------VPGLPGEPGR 687 EG +G G L L+GP+G FPG PGPPG PG+PG+PG Sbjct: 783 GPRGDPGCPGAEGPAGIPGFL-GLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGL 841 Query: 688 FGVNSS-----------DV--PGPAG------LPGVPGREGPPGFPGLPGP------PGP 722 G S DV PGPAG LPG PG GPPG PG+PGP PGP Sbjct: 842 PGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGP 901 Query: 723 PGREGP------PGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGP 776 PG +GP PG G++G G G PG KG G G +G G+ GL GA G GPPG Sbjct: 902 PGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGD 961 Query: 777 PGP---------PGPPGPGLPAGFDDMEGSGG-PFWSTARSADGPQGPPGL----PGLKG 822 G PG PGP GF G G P R G GPPG PG KG Sbjct: 962 EGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKG 1021 Query: 823 DPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKG------DRGSRGEKGDPGKDG 876 PG PG PG G G G GFPGLPG +G G GP G RG +G KGDP Sbjct: 1022 QPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASH- 1080 Query: 877 VGQPGLPGPPGPPG-PVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGN--------- 926 G PG G PG PG P + + + + + GP G PG G PG +GP G Sbjct: 1081 FGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGL 1140 Query: 927 LGSKGERGSPGPKGEKGEPGSIFSPDGGALGPA-------------QKGAKGEPGFR--G 971 G GE G PGP+G +G+PG P G GP+ QKG KG G G Sbjct: 1141 RGQPGEMGDPGPRGLQGDPGIPGPP--GIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVG 1198 Query: 972 PPGPYGRPGYKGEIGFPGRPG--RPGMNGLKGEKGEPGDA-------SLGFGMRGMP--G 1020 PPGP G PG KGE G PG PG PG G KG G PG + + G + +P G Sbjct: 1199 PPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPG 1258 Query: 1021 PPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGN----QGPPGPKGAKGEVGPPGPPGQ 1076 PPG GPPGP G PGPPGLPG+ +G PG G G GPPGPPG Sbjct: 1259 PPGDQGPPGPDGP----------RGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGP 1308 Query: 1077 FPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYP---GIP 1133 + G+KG G G +G G PG G G LPGPPG GP G P G P Sbjct: 1309 PGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKG--LPGPPGRKGPTGLPGPRGEP 1366 Query: 1134 GPKGE-----SIRGQPGPPGPQGPPGI------------------GYEGRQGPPGPPGPP 1170 GP + I G PG PG +GP G G +GR+G G PG P Sbjct: 1367 GPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSP 1426 Query: 1171 GPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSG 1206 GPP G + PG PGPPGP G PG G G Sbjct: 1427 GPPGRKGDTGED-GYPGGPGPPGPIGDPGPKGFGPG 1461 Score = 466 bits (1199), Expect = e-131 Identities = 378/1011 (37%), Positives = 433/1011 (42%), Gaps = 279/1011 (27%) Query: 445 ETGAALKPRLPAPP----PVTTPPLAGGSSTEDSRSEE-----VEEQTTVASLGAQTLPG 495 E G+ P P P P+ P G S + R + ++ G PG Sbjct: 60 EKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPG 119 Query: 496 SDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSPCLPGP-------- 545 D + G PG R K G G G +G+PG PG G GP G PG Sbjct: 120 LDGIPGHPGP---PGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSV 176 Query: 546 ------------------PGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEP 587 PGLP GPAGP PG G GPPG+ G PG G P Sbjct: 177 FILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPT--GYPGEPGLVGPPGQPGRPGLKGNP 234 Query: 588 G--------DPGEDGKPGDTGP------------------QGFPGTPGDVGPKGDKGDPG 621 G DPGE G+ G GP +G PG G GP G KG+ G Sbjct: 235 GVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESG 294 Query: 622 VGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS-GFGGD--LEALRGPRGFPGP---PGP 675 +G +G G G PGP G + F ++G G GD L L GP+G PG PGP Sbjct: 295 IGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGP 354 Query: 676 PGV-----------PGLPGEPGRFGVNSSDV--PGPAGLPGVPGRE--------GPPGFP 714 PGV PG PG PGR+G + DV PGP GL G PG GP GFP Sbjct: 355 PGVLVTPPLPLKGPPGDPGFPGRYG-ETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFP 413 Query: 715 GLPGPPGP---PGR-EGPPGRTGQKGSLGEAGAPGHKG---------SKGAPGPAGARGE 761 GLPG PG PGR + PG+ G+ GS G GAPG +G S G PGP G +G+ Sbjct: 414 GLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGK 473 Query: 762 SGLAGAPGPAGP----------PGPPGPPGPPG-PGLPAGFDDMEGSGGPFWSTARSADG 810 G G GP G PGP GPPGPPG PG D+ G P W + G Sbjct: 474 VGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDL---GLPGWLGTKGDPG 530 Query: 811 P---QGPPGLPGLKGDPGVPGLPGAKGEV------------GADGVPGFPGLPGREGIAG 855 P +GPPGLPG G G PG GAKG++ G DG PGFPG PG G G Sbjct: 531 PPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDG 590 Query: 856 PQGPKGDRGSRGEK--------------GDPGKDG-VGQPGL--PGPPGPPG-------P 891 G KGD G G+ G PGK G VG PGL PGPPG G P Sbjct: 591 HAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHP 650 Query: 892 VVY----VSEQDGSVLSV----PGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKG 943 V + Q G +S PG G PGF G PGP G G G+ G GS G KG G Sbjct: 651 GVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPG 710 Query: 944 EPGSIFSPDGGALGPAQKGAKGEPGFRG--------PPGPYGRPGYKGEIGFPGRP---- 991 PG+ P P +G G+PGF G PPGP G PG G+ G PG P Sbjct: 711 TPGTAEIPGP----PGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGH 766 Query: 992 -------GRPGMNGLKGEKGEPGDASL-------GF----GMRGMPGPPGPPGPPGPPGT 1033 G G+ G+KG +G+PG GF G +G G G PG PGPPG Sbjct: 767 LGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGH 826 Query: 1034 PVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKG 1093 + +PG PG PG+ G PG KG G+VGPPGP G MKG G Sbjct: 827 SC-ERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAG------------MKGLPG 873 Query: 1094 DRGDAGQKGERGEPGGGGFFGSS-LPGPPGPPGPRGYPGIPGPKGESIRGQPGP---PGP 1149 G G G G PG G FG LPGPPGP GPRG PG PG GE RG+PG PG Sbjct: 874 LPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGE--RGKPGAEGCPGA 931 Query: 1150 QGPPG-------------------IGYEG---------RQGPPGPPGPPGPPSFPGP--- 1178 +G PG IG G ++G PG PGPPG FPG Sbjct: 932 KGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGD 991 Query: 1179 ---------------------HRQTISVPGPPGPPGPPGPPGTMGASSGVR 1208 HR PG G PGPPGPPG G S+G+R Sbjct: 992 KGTPGMQGRRGEPGRYGPPGFHR---GEPGEKGQPGPPGPPGPPG-STGLR 1038 Score = 407 bits (1047), Expect = e-113 Identities = 287/720 (39%), Positives = 332/720 (46%), Gaps = 148/720 (20%) Query: 489 GAQTLPGSDSVSTWDGSVRTPGGRVKEG-----GLKGQKGEPGVPGPPGRAGPPGSPCLP 543 GA +PG + + GS PGG+ + G G G KG PG+PG PG GPPG P +P Sbjct: 831 GAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIP 890 Query: 544 GP---PGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG 600 GP GLP P P GP G L PG G G PG +G PG GEPG+ G G PGD Sbjct: 891 GPFGDDGLPGPPGPKGPRG--LPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGD-- 946 Query: 601 PQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPG-PSFRHDKLTFIDMEGS---- 654 +G G G +GP GD+G+ + ++G PG GPPG G P R DK T M+G Sbjct: 947 -RGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGT-PGMQGRRGEP 1004 Query: 655 ---GFGGDLEALRGPRGFPGPPGPPGVPG---------LPGEPGRFGVNSSDVPGPAGLP 702 G G G +G PGPPGPPG PG PG PG G S PGP G Sbjct: 1005 GRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGS--PGPPGFS 1062 Query: 703 GVPGREGPPGFPGLP----GPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGA 758 G+ G GP G G P GPPGP G G PG G G+ GE G PG +G +G+PG G Sbjct: 1063 GIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGP 1122 Query: 759 RGESG------------LAGAPGPAGPPGP------PGPPGPPG-------PGLPAGFDD 793 G SG L G PG G PGP PG PGPPG PGL G Sbjct: 1123 PGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLN-GLHG 1181 Query: 794 MEGSGGPFWSTARSADGPQGPPGLPGLK---GDPGVPGL--PGAKGEVGADGVPGFPGLP 848 ++G G ++ GP GP G+PGLK GDPG PG+ PG +G+ G G PG G P Sbjct: 1182 LKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPP 1241 Query: 849 GREGIA-------------GPQGPKGDRGSRGEKGDPGKDG-----------VGQPGLPG 884 G G G QGP G G RG G PG G G PG PG Sbjct: 1242 GPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPG 1301 Query: 885 PPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGE 944 PPGPPGP Y G +G+ G GFPGP GP G G GE+G PGP G KG Sbjct: 1302 PPGPPGPPGY-----KGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKG- 1355 Query: 945 PGSIFSPDGGALGPAQ-------KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMN 997 P + P G PA G G PG RGP G G PG +G G PG G PG++ Sbjct: 1356 PTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSG-PGCKGEPGLD 1414 Query: 998 GLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQG 1057 G + G+ G+PG PGPPG G G E PG PG PG G Sbjct: 1415 GRR-------------GVDGVPGSPGPPGRKGDTG----------EDGYPGGPGPPGPIG 1451 Query: 1058 PPGPKG-AKGEVG----------------PPGPPGQFP-FDFLQLEAEMKGEKGDRGDAG 1099 PGPKG G +G P G P + + L LE + K D G AG Sbjct: 1452 DPGPKGFGPGYLGGFLLVLHSQTDQEPTCPLGMPRLWTGYSLLYLEGQEKAHNQDLGLAG 1511 Score = 301 bits (770), Expect = 4e-81 Identities = 212/507 (41%), Positives = 236/507 (46%), Gaps = 83/507 (16%) Query: 754 GPAGARG--------ESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTA 805 GP G R E G G PGP GP GP GP G PGP +G M G GP + Sbjct: 45 GPCGGRDCSVCHCVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAG 104 Query: 806 RSAD-GPQGPPGLPGLKGDPGVPGLPGAKGEVGA---DGVPGFPGLPGREGIAGPQGPKG 861 D GP G PG PGL G PG PG PG +G+ G +G G PG PG G GP GP G Sbjct: 105 DKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLG 164 Query: 862 DRGSRGEKGDP--------GKDGV-GQPGLPGPPG------PPGPVVYVSEQDGSVLSVP 906 G +GEKG+ G G G PGLPG PG P GP Y E ++ P Sbjct: 165 HPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEP--GLVGPP 222 Query: 907 GPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGS--IFSPDGGALGPAQKGAK 964 G GRPG G PG +G KG+ G PG G++G PG + P L +KG K Sbjct: 223 GQPGRPGLKGNPG-------VGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIK 275 Query: 965 GEPGFRGPPGPYGR--------------PGYKGEIGFPGRPGRPGMNGLKGEKGEPGDAS 1010 G PG G PGP GR PG+ G G PG G PG GLKGE G GD Sbjct: 276 GIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPG 335 Query: 1011 LGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGP-PGLPGNQGPPGPKGAKGEVG 1069 L FG+ G G PG G PGPPG V + P P G PG+ G PG G G+VG Sbjct: 336 L-FGLIGPKGDPGNRGHPGPPGVLV---------TPPLPLKGPPGDPGFPGRYGETGDVG 385 Query: 1070 PPGPPGQFPFDFLQLEAEM-KGEKGDRGDAGQKGERGEPGGGGFFG--SSLPGPPGPPGP 1126 PPGPPG L E G G G G G G PG G G S PG PG PG Sbjct: 386 PPGPPG-----LLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGS 440 Query: 1127 RGYPGIPG----PKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQT 1182 G PG PG P I G PGPQG +G+ GPPG GP G G Sbjct: 441 PGLPGAPGLQGLPGSSVIYCSVGNPGPQG-----IKGKVGPPGGRGPKGEKGNEG---LC 492 Query: 1183 ISVPGPPGPPGPPGPPGTMGASSGVRL 1209 PGP GPPGPPG PG G+ + L Sbjct: 493 ACEPGPMGPPGPPGLPGRQGSKGDLGL 519 Score = 191 bits (486), Expect = 4e-48 Identities = 145/357 (40%), Positives = 163/357 (45%), Gaps = 53/357 (14%) Query: 894 YVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDG 953 Y+ G SV G G PGP GP+G +G G G G GEKG G P G Sbjct: 43 YIGPCGGRDCSVCHCVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGD-RGPPG 101 Query: 954 GALGPAQKGAKGEPGF---------RGPPGPYGRPGYKGEIGFPGRPGRPGMNGL----- 999 A KG G PGF GPPGP G+PG G G G PG PG G Sbjct: 102 AAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGG 161 Query: 1000 ----KGEKGEPGDASLGFG-MRGMPGPPGPPGPPGPPGT-----PVYDSNVFAESSRPGP 1049 GEKGE G++ G ++G+ G G PG PG PG+ P + E GP Sbjct: 162 PLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGP 221 Query: 1050 PGLPGNQGPPGPK--GAKGEVGPPGPPGQ--FPFDFLQLEAE----MKGEKGDRGDAGQK 1101 PG PG G G G KG++G PG GQ P L +E KGEKG +G G Sbjct: 222 PGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMV 281 Query: 1102 GERGEPGGGGFFG---------SSLPGPPGPPGPRGYPGIPGPKGE-SIRGQPGPPGPQG 1151 G G PG G G PGP G PG G PG PG KGE + G PG G G Sbjct: 282 GLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIG 341 Query: 1152 PPG-IGYEGRQGPPG----PP----GPPGPPSFPGPHRQTISVPGPPGPPGPPGPPG 1199 P G G G GPPG PP GPPG P FPG + +T V GPPGPPG G PG Sbjct: 342 PKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDV-GPPGPPGLLGRPG 397 Score = 122 bits (307), Expect = 2e-27 Identities = 87/223 (39%), Positives = 96/223 (43%), Gaps = 29/223 (13%) Query: 418 DEEGDDSDGASGDSGS-GLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRS 476 D+ DG G G GL + +LLR E G P P PP PP Sbjct: 1262 DQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPP------------ 1309 Query: 477 EEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGP 536 G + PG D G V PG + G G GE G+PGPPGR GP Sbjct: 1310 ------------GYKGFPGCDGKDGQKGPVGFPGPQGPH-GFPGPPGEKGLPGPPGRKGP 1356 Query: 537 PGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKP 596 G P G PG P V P P L PG +GP G G G G G PG GE G Sbjct: 1357 TGLPGPRGEPGPPADVDDC-PRIPGLPGAPGMRGPEGAMGLPGMRGPSG-PGCKGEPGLD 1414 Query: 597 GDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPG 638 G G G PG+PG G KGD G+ G G GPPGP G PGP G Sbjct: 1415 GRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKG 1457 >gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] Length = 1745 Score = 514 bits (1325), Expect = e-145 Identities = 344/829 (41%), Positives = 401/829 (48%), Gaps = 114/829 (13%) Query: 463 PPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQK 522 PP G + E + + + G + G D G+V PG G +G Sbjct: 588 PPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPG-EPGPPGQQGNH 646 Query: 523 GEPGVPGP------PGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPG--- 573 G G+PGP PG GPPG+P +PG PG P+ G GP + G QGPPG Sbjct: 647 GSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEK--GAQGPPGSAG 704 Query: 574 PPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQG 632 PPG G G G G+ G G+ G+ G GFPG GDVG KGD+G PG G RG GP+G Sbjct: 705 PPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEG 764 Query: 633 PPG---------PPGPSFRHDKLTFIDMEGS----------GFGGDL------------- 660 P G PPG + KL + G GF G L Sbjct: 765 PKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTG 824 Query: 661 -EALRGPRGFPGPPGPPGVPGLPGEPGRFG-VNSSDVPGPAGLPGVPGREGPPGFPGLPG 718 L G RG PG G G PG G+PG G V PG G G+PG +GPPGFPG G Sbjct: 825 QPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKG 884 Query: 719 PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPG 778 PPG G++G PG GQ+G L G +G G PGPAG G G G GP G GPPG Sbjct: 885 PPGHQGKDGRPGHPGQRGEL------GFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPG 938 Query: 779 PPGPPG-PGLPAGFDDMEGSGGPFWSTA-RSADGPQGPPGLPGLKGDPGVPGLPGAKGE- 835 PPGPPG GLP G + EG+ G +GP G G PG KG PG PG G KG+ Sbjct: 939 PPGPPGEQGLP-GLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDK 997 Query: 836 -----VGADGVPGFP---------GLPGREGIAGPQGPKGDRGSRGEKGDPGKDGV-GQP 880 VGA+G PG GLPG+ G GP GP G +GSRGE+G PG G G P Sbjct: 998 GPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIP 1057 Query: 881 GLPGPPGPPGPVVYVSEQ-DGSVLSVP------------GPEGRPGFAGFPGPAGPKGNL 927 G GP GPPG E+ D + P GP G+PG G G GP G Sbjct: 1058 GPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGAD 1117 Query: 928 GSKGERGSPGPKGEKGEPG-----SIFSPDG--GALG-PAQKGAKGEPGFRGP---PGPY 976 G++G RG PG G+KG+ G + P G G G P +KG G+ G GP PGP Sbjct: 1118 GAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPR 1177 Query: 977 GRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVY 1036 G G G G PG PG G G GEKGE GDA G PGPPG PG PGP G Sbjct: 1178 GPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDA-------GDPGPPGAPGIPGPKG---- 1226 Query: 1037 DSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRG 1096 D +S G G PG +GPPG GAKG VGP G PG + + G G++G Sbjct: 1227 DIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKG 1286 Query: 1097 DAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-I 1155 D G G G PG G G+ PGPPG GP G+ G G +GE +G G PGP GPPG Sbjct: 1287 DPGDVGGPGPPGASGEPGA--PGPPGKRGPSGHMGREGREGE--KGAKGEPGPDGPPGRT 1342 Query: 1156 GYEGRQGPPGPPGPPGPPSFPGPHRQ--TISVPGPPGPPGPPGPPGTMG 1202 G G +GPPG GP G PGP + + PG GPPGP GP G G Sbjct: 1343 GPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPG 1391 Score = 510 bits (1313), Expect = e-144 Identities = 349/869 (40%), Positives = 417/869 (47%), Gaps = 134/869 (15%) Query: 424 SDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEE-- 481 SDG G G + + G+A P P P V +G + + E+ E+ Sbjct: 678 SDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGT--SGNRGLQGEKGEKGEDGF 735 Query: 482 ---QTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPG 538 + V G Q PG+ DG P G + G G++G PG G G+ G PG Sbjct: 736 PGFKGDVGLKGDQGKPGAPGPRGEDG----PEGPKGQAGQAGEEGPPGSAGEKGKLGVPG 791 Query: 539 SPCLPGPPG------LPCPVSPLGPAGPALQT----VPGPQGPPGPPGRDGTPG------ 582 P PG PG P P+ P+G G + +T + G +GPPG G G PG Sbjct: 792 LPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPG 851 Query: 583 ------RDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPG-VGERGPPGPQGPPG 635 +DG PG PGE G PG GP GFPG G G +G G PG G+RG G QG G Sbjct: 852 PKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTG 911 Query: 636 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 695 PPGP+ + G G++ L G RG PGPPGPPG GLPG GR G Sbjct: 912 PPGPAGV--------LGPQGKTGEVGPL-GERGPPGPPGPPGEQGLPGLEGREGAKGELG 962 Query: 696 P-------GPAGLPGVPGREGPPGFPGLPG------PPGPPGREGPPGRTGQKGSLGEAG 742 P GPAGL G PG +G PG PG G PPGP G G PG G G G G Sbjct: 963 PPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIG 1022 Query: 743 APGHKGSKGAPGPAGARGESGLAGAPGPAGP---PGPPGPPGPPGPGLPAGFDDMEGS-G 798 PG GS+G GPAG +G G G PGP G PGP GP GPPG P+G + +G G Sbjct: 1023 LPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVG 1082 Query: 799 GPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAG--- 855 P ++ G GPPG PG++G G PG PGA G G G PG G G +G+ G Sbjct: 1083 APGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVG 1142 Query: 856 ---PQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGR 911 P G +G G GEKG+ G G +G G PGP GP GP + +G+ +PG G+ Sbjct: 1143 VIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGP----TGSEGTP-GLPGGVGQ 1197 Query: 912 PGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRG 971 PG G G G G+ G G G PGPKG+ GE G P G A P +KG GE G +G Sbjct: 1198 PGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDS-GPSGAAGPPGKKGPPGEDGAKG 1256 Query: 972 PPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPP 1031 GP G PG ++G PG PG G++G GEKG+PGD G PGPPG G PG P Sbjct: 1257 SVGPTGLPG---DLGPPGDPGVSGIDGSPGEKGDPGDV-------GGPGPPGASGEPGAP 1306 Query: 1032 GTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGE 1091 G P + GP G G +G G KGAKGE GP GPPG+ G Sbjct: 1307 GPP----------GKRGPSGHMGREGREGEKGAKGEPGPDGPPGR---------TGPMGA 1347 Query: 1092 KGDRGDAGQKGERGEPGGGGFFG----SSLPGPPGPPGPRGYPGIPG---PKGES----I 1140 +G G G +G RG PG G G GPPGP GP G PG+ G PKGE + Sbjct: 1348 RGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGL 1407 Query: 1141 RGQPGPPGP------QGPPGI-GYEGRQGPPGPPGP------PGPPSFPGPHRQ------ 1181 G GPPG QG PG+ G G +G PGPPGP PGPP GP Q Sbjct: 1408 IGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGS 1467 Query: 1182 --TISVPGPPGPPGPPGPPGTMGASSGVR 1208 ++ G GP GPPGPPG G+R Sbjct: 1468 PGSMGPRGDTGPAGPPGPPGAPAELHGLR 1496 Score = 508 bits (1308), Expect = e-143 Identities = 403/1158 (34%), Positives = 483/1158 (41%), Gaps = 260/1158 (22%) Query: 263 HFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYTEP 322 HFP +FSLL +R VL +I D A L G+ L + LL Sbjct: 85 HFPE----NFSLLITLRGQPANQSVLLSIYDERGARQL-GLALGPA------LGLL---- 129 Query: 323 GAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPGAG 382 G ++ G+W +A+S+ G V L DCE Q L R + + AG Sbjct: 130 --GDPFRPLPQQVNLTDGRWHRVAVSIDGEMVTLVADCEA-QPPVLGHGPRFISI---AG 183 Query: 383 LFVAQAGGADPDKFQGVIAELKVRRDPQ---------------VSPMHCLDEEGDDSDGA 427 L V F+G I EL + DPQ ++P + +G+ Sbjct: 184 LTVLGTQDLGEKTFEGDIQELLISPDPQAAFQACERYLPDCDNLAPAATVAPQGEPETPR 243 Query: 428 SGDSGSGLG-------------------------------DARELLREETGAALKPRLPA 456 G G G + ++ + ET A P P Sbjct: 244 PRRKGKGKGRKKGRGRKGKGRKKNKEIWTSSPPPDSAENQTSTDIPKTETPAPNLPPTPT 303 Query: 457 PPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKE- 515 P VT+ G ++T RS + + T + +L + + D S P R E Sbjct: 304 PLVVTSTVTTGLNATILERSLDPDSGTELGTLETKAAREDEE---GDDSTMGPDFRAAEY 360 Query: 516 -----------GGLKGQKGE-------------PGVPGPPGRAGPPGSPCLPGPPGLPCP 551 G KG KGE PG PGP G GP G PGPPG P Sbjct: 361 PSRTQFQIFPGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGP---PGPPGFPGD 417 Query: 552 VSPLGPAG----PALQTVPGP--------------------------------------- 568 P GPAG P + + GP Sbjct: 418 PGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSM 477 Query: 569 QGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQ------------------------GF 604 +GPPGP G G PG G PG PG G+ G GPQ G Sbjct: 478 KGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGA 537 Query: 605 PGTPGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFG 657 G PGD GPKGD+G G+ G+RG G G PGPPG G Sbjct: 538 RGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGE 597 Query: 658 GDLEALRGPRGFPGPPGPPGV---------------PGLPGEPGRFGVNSSD-VPGPAGL 701 L GPRG PGP G PGV PG PG PG+ G + S +PGP GL Sbjct: 598 PGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGL 657 Query: 702 PGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGE 761 G PG +GPPG PG+PG PG G G PG G G G G PG G G PGP G +G Sbjct: 658 IGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGT 717 Query: 762 SGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLK 821 SG G G G G G PG G G G+ GP R DGP+GP G G Sbjct: 718 SGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGP-----RGEDGPEGPKGQAGQA 772 Query: 822 GDPGVPGLPGAKGEVGADGVPGFPGLPGRE---GIAGPQGPKGDRGSRGEKGDPGKDGV- 877 G+ G PG G KG++G G+PG+PG PG + G GP GP G++G G+ G PG +G Sbjct: 773 GEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGER 832 Query: 878 ---------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGF---AGFPGPAGPKG 925 GQPG G PGP G V QDG+ +PG +G PG GFPGP GP G Sbjct: 833 GPPGSRGERGQPGATGQPGPKGDV----GQDGAP-GIPGEKGLPGLQGPPGFPGPKGPPG 887 Query: 926 NLGSKGERGSPGPKGEKGEPGSIFSP-DGGALGPAQK-GAKGEPGFRGPPGPYGRPGYKG 983 + G G G PG +GE G G P G LGP K G G G RGPPGP G PG +G Sbjct: 888 HQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQG 947 Query: 984 EIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGT--------PV 1035 G GR G G G G G+ G A G+RG PGP G PG PGP G PV Sbjct: 948 LPGLEGREGAKGELGPPGPLGKEGPA----GLRGFPGPKGGPGDPGPTGLKGDKGPPGPV 1003 Query: 1036 YDSNVFAESSRPGP------PGLPGNQGPPGP---KGAKGEVGPPGPPGQ--FPFDFLQL 1084 + E GP PG G++GP GP KG++GE GPPGP G+ P L Sbjct: 1004 GANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPL 1063 Query: 1085 ----EAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKG-ES 1139 A GE+GD+GD G G +G G G G PG PG GP G+PG PG G + Sbjct: 1064 GPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGP--PGQPGIRGPAGHPGPPGADGAQG 1121 Query: 1140 IRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPGPP---------SFPGPHRQTISVPGPP 1189 RG PG G +G G+ G+ G GPPG G PGPP GPH PGP Sbjct: 1122 RRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPH----GAPGPR 1177 Query: 1190 GPPGPPGPPGTMGASSGV 1207 GP GP G GT G GV Sbjct: 1178 GPQGPTGSEGTPGLPGGV 1195 Score = 487 bits (1254), Expect = e-137 Identities = 331/805 (41%), Positives = 378/805 (46%), Gaps = 114/805 (14%) Query: 489 GAQTLPGSDSVST---WDGSVRTPGGRVKEG-----------GLKGQKGEPGVPGPPGRA 534 GA+ LPG +DG PG + + G G G++G G PGP G+A Sbjct: 536 GARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQA 595 Query: 535 GPPGSPCLPGPPGLPCPVSPLGPAG----PALQTVPGPQGPPGPPGRDGTPGRDGEPGDP 590 G PG L GP G P P G G P + GP G PGPPG+ G G G PG Sbjct: 596 GEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQ 655 Query: 591 GEDGKPGDTGPQGFPGTPGDVGPKGDKGDPG-------VGERGPPGPQGPPGPPGPSFRH 643 G G PG+ GP G PG PG G G G PG G +GPPG GPPG PGP Sbjct: 656 GLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVK 715 Query: 644 DKLTFIDMEGS----------GFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSS 693 ++G GF GD+ L+G +G PG PGP G G G G+ G Sbjct: 716 GTSGNRGLQGEKGEKGEDGFPGFKGDV-GLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGE 774 Query: 694 DVP----------GPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGA 743 + P G GLPG PGR GP G G PGP GP G +G G+TGQ G GE G Sbjct: 775 EGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGP 834 Query: 744 PGHKGSKGAPG------PAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGS 797 PG +G +G PG P G G+ G G PG G PG GPPG PGP P G +G Sbjct: 835 PGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGR 894 Query: 798 GG-PFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPG------FPGLPGR 850 G P G GPPG G+ G G G G GE G G PG PGL GR Sbjct: 895 PGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGR 954 Query: 851 EGIAG---PQGPKGDRGSRGEKGDPG-KDGVGQPG---LPGPPGPPGPV-VYVSEQDGSV 902 EG G P GP G G G +G PG K G G PG L G GPPGPV S + Sbjct: 955 EGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGP 1014 Query: 903 LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDG--GALGPAQ 960 L G G PG +G GP GP G GS+GERG PGP G+ G PG + P G GA GP+ Sbjct: 1015 LGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPL-GPLGPPGAAGPSG 1073 Query: 961 K----------GAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG---EPG 1007 + G KG G +G GP G+PG +G G PG PG G G +G G + G Sbjct: 1074 EEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKG 1133 Query: 1008 DASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE 1067 D + G G+ GPPG G PGPPG + + GP G PG +GP GP G++G Sbjct: 1134 DDGVR-GFVGVIGPPGLQGLPGPPG----EKGEVGDVGSMGPHGAPGPRGPQGPTGSEGT 1188 Query: 1068 VGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFG-------SSLPGP 1120 G PG GQ GEKG+RGDAG G G PG G G S G Sbjct: 1189 PGLPGGVGQ---------PGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGA 1239 Query: 1121 PGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPH 1179 GPPG +G PG G KG G G PG GPPG G G G PG G PG PGP Sbjct: 1240 AGPPGKKGPPGEDGAKGSV--GPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGP- 1296 Query: 1180 RQTISVPGPPGPPGPPGPPGTMGAS 1204 PG G PG PGPPG G S Sbjct: 1297 ------PGASGEPGAPGPPGKRGPS 1315 Score = 342 bits (877), Expect = 2e-93 Identities = 243/623 (39%), Positives = 275/623 (44%), Gaps = 107/623 (17%) Query: 489 GAQTLPGSDSVSTWDGSVRTPGGRVKEG-----GLKGQKGEPGVPGPPGRAGPPGSPCLP 543 G Q LPG + G + PG KEG G G KG PG PGP G G G P Sbjct: 944 GEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPV 1003 Query: 544 GPPGLPCPVSPLGPAGP-ALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQ 602 G G P PLGPAG L G +GP GP G+ G+ G G PG G+DG PG GP Sbjct: 1004 GANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPL 1063 Query: 603 GFPGTPGDVGPKGDKGDPGV----------GERGPPG------PQGPPGPPGPSFRHDKL 646 G PG G G +GDKGD G G+ GPPG P G PGPPG + Sbjct: 1064 GPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRR 1123 Query: 647 TFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFG-------VNSSDVPGPA 699 + G G D G RGF G GPPG+ GLPG PG G + PGP Sbjct: 1124 GPPGLFGQK-GDD-----GVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPR 1177 Query: 700 G---------LPGVPGR------------------EGPPGFPGLPGPPG----------- 721 G PG+PG GPPG PG+PGP G Sbjct: 1178 GPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPS 1237 Query: 722 ----PPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPP 777 PPG++GPPG G KGS+G G PG G G PG +G G G G PG G PGPP Sbjct: 1238 GAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPP 1297 Query: 778 GP------PGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPG 831 G PGPPG P+G EG G A+ GP GPPG G G G PG G Sbjct: 1298 GASGEPGAPGPPGKRGPSGHMGREGREGE--KGAKGEPGPDGPPGRTGPMGARGPPGRVG 1355 Query: 832 AKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPG 890 +G G G G PGL G G GP GP G G G KGD G G G GL G GPPG Sbjct: 1356 PEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPG 1415 Query: 891 PVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFS 950 +Q +PG +G PG G PGP GP G+LG G G GP G+KG GS Sbjct: 1416 EAGEKGDQ-----GLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGS--- 1467 Query: 951 PDGGALGPAQKGAKGEPGFRGPPGPYGRP----GYKGEIGFPGRPGRPGMNGLKGEKGEP 1006 P G +G+ G GPPGP G P G + F P GL E+ Sbjct: 1468 -------PGSMGPRGDTGPAGPPGPPGAPAELHGLRRRRRFVPVPLPVVEGGL--EEVLA 1518 Query: 1007 GDASLGFGMRGMPGPPGPPGPPG 1029 SL + + PPG PG Sbjct: 1519 SLTSLSLELEQLRRPPGTAERPG 1541 Score = 266 bits (679), Expect = 1e-70 Identities = 178/455 (39%), Positives = 199/455 (43%), Gaps = 64/455 (14%) Query: 419 EEGDDSD-------GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSST 471 EEGD D G+ GD G + +R G P PP G Sbjct: 1074 EEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKG 1133 Query: 472 EDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRT------PGGRVKEG--------G 517 +D V + G Q LPG G V + PG R +G G Sbjct: 1134 DDGVRGFVG---VIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPG 1190 Query: 518 LKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGR 577 L G G+PG G G G G P PG PG+P P +G G + GP G GPPG+ Sbjct: 1191 LPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDS-----GPSGAAGPPGK 1245 Query: 578 DGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPG-VGERGPPGPQGPPGP 636 G PG DG G G G PGD GP G PG G G G+KGDPG VG GPPG G PG Sbjct: 1246 KGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGA 1305 Query: 637 PGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPG---LPGEPGRFGVNSS 693 PGP + + EG E +G +G PGP GPPG G G PGR G Sbjct: 1306 PGPPGKRGPSGHMGREGR------EGEKGAKGEPGPDGPPGRTGPMGARGPPGRVG---- 1355 Query: 694 DVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAP 753 P GL G+PG G PG G PG GPPG GP G G KG G G GH G G Sbjct: 1356 ----PEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLI 1411 Query: 754 GPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQG 813 GP G GE G G PG GPPGP G PGPPGP + G P GP G Sbjct: 1412 GPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGP--------IGSLGHP---------GPPG 1454 Query: 814 PPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLP 848 G G KG G PG G +G+ G G PG PG P Sbjct: 1455 VAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAP 1489 Score = 77.4 bits (189), Expect = 1e-13 Identities = 92/292 (31%), Positives = 112/292 (38%), Gaps = 47/292 (16%) Query: 949 FSPDGGALGPAQKGA-KGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEK---- 1003 + PD L PA A +GEP P P + KG GR G+ G K K Sbjct: 220 YLPDCDNLAPAATVAPQGEPE---TPRPRRKGKGKGRKKGRGRKGK----GRKKNKEIWT 272 Query: 1004 -GEPGDASLGFGMRGMPGP--PGPPGPPGPPGTPVYDSNVFAES------SRPGPPGLPG 1054 P D++ +P P P PP P TP+ ++ R P Sbjct: 273 SSPPPDSAENQTSTDIPKTETPAPNLPPTP--TPLVVTSTVTTGLNATILERSLDPDSGT 330 Query: 1055 NQGPPGPKGAK----GEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGG 1110 G K A+ G+ GP DF E + + AG+KG +GEP Sbjct: 331 ELGTLETKAAREDEEGDDSTMGP------DFRAAEYPSRTQFQIFPGAGEKGAKGEPAVI 384 Query: 1111 GFFGSSLPGPPGPPGPRGYPGIPGPKGE-SIRGQPGPPGPQGPPGI-GYEGRQGPPGPP- 1167 G GPPG PGP+G G GP G G PGPPGP G PGI G +G +GPPG Sbjct: 385 EK-GQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVI 443 Query: 1168 ---------GPPGPP-SFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRL 1209 GPP SF Q + GPPGP G G V L Sbjct: 444 MMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGL 495 >gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo sapiens] Length = 1424 Score = 512 bits (1318), Expect = e-144 Identities = 357/880 (40%), Positives = 410/880 (46%), Gaps = 160/880 (18%) Query: 426 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 485 G GD G LR + G +P P V P G E + S E +Q Sbjct: 551 GVPGDPG---------LRGQPGRKGLDGIPGTPGVKGLP---GPKGELALSGEKGDQGPP 598 Query: 486 ASLGAQTLPGSDSVSTWDGSVRTPG-GRVKEGGLKGQKGEPGVPGPPGRAGPPG----SP 540 G+ PG G PG G E GL+G +G PG PGPPG AGP G S Sbjct: 599 GDPGSPGSPGPA------GPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652 Query: 541 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGR------DGTPGRDGEPGDPGED- 593 +PGPPG P GP G PGPQGPPG PG G PG DGEPG PG Sbjct: 653 PVPGPPGPP------GPPGH-----PGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF 701 Query: 594 -GKPGDTGPQGFPGT---------------PGDVGPKGDKGDPGVGERGPPGPQGPPGPP 637 G PG G QGFPGT PG G G KG+P V G PG G PG Sbjct: 702 PGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGER 761 Query: 638 GPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPG 697 G S H ++ + G E L GPRG PG PGPPG G PG + +PG Sbjct: 762 GNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPG 821 Query: 698 PAGLPGVPGREG---PPGFPGLPG--PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA 752 GL G GR G P G PG+PG G PG G PG G +G +G G G+ G+ G Sbjct: 822 LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGI 881 Query: 753 PGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGLPAGFDDMEGSGGPFWSTARSA 808 GP G G G+ G PG GPPGPPG PG PG PG+P G G+ G A+ Sbjct: 882 LGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIP-GVKGQRGTPG-----AKGE 935 Query: 809 DGPQGPPG------LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGD 862 G +G PG + G KG+PG+ G G GE G GVPG PGL G +G+ GP GP G Sbjct: 936 QGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGP 995 Query: 863 RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGF---- 917 RG G G+PG+ G+ G PG G G PG S+ L PG GRPG G Sbjct: 996 RGDLGSTGNPGEPGLRGIPGSMGNMGMPG-----SKGKRGTLGFPGRAGRPGLPGIHGLQ 1050 Query: 918 -------------PGPAGPKGN------LGSKGERGSPGPKGE------KGEPGSIFSPD 952 PGP GP G+ +G KGE G PGP G +G PGS SP Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110 Query: 953 -GGALGP-------AQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG 1004 G GP KG G PG RGPPG G PG G +G G GR G+ G GEKG Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170 Query: 1005 EPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR-----------PGPPGLP 1053 E G G RG PG G G G PG P A PGPPGLP Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230 Query: 1054 G--------NQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERG 1105 G N+GPPG +G+ G GPPGPPG + + G KGD+G G G +G Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPG----------SHVIGIKGDKGSMGHPGPKG 1280 Query: 1106 EPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE-SIRGQPGPPGPQGPPGIGYEGRQGPP 1164 PG G G PPG G G PG+PGP+G+ +G PG G +G PG + G GPP Sbjct: 1281 PPGTAGDMG-----PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG--FLGSIGPP 1333 Query: 1165 GPPGPPGPPSFPGPHR--QTISVPGPPGPPGPPGPPGTMG 1202 GP GP GPP G + IS+PG PGPPG PG PG G Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373 Score = 480 bits (1235), Expect = e-135 Identities = 351/939 (37%), Positives = 415/939 (44%), Gaps = 186/939 (19%) Query: 423 DSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQ 482 D+ GD G+ R G + P +P P + P L G + + E Sbjct: 348 DTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERG 407 Query: 483 TTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCL 542 A PGS + G +PG G + +KG PG G PG G PG P + Sbjct: 408 RP--GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGV 465 Query: 543 PGP---PGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT 599 GP PGL C P P P L +PG G G PGR G G G PG PG G PG Sbjct: 466 DGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGF- 524 Query: 600 GPQGFPGTPGDVGPKGDK-------------GDPGV-GERGPPGPQGPPGPPGPSFRHDK 645 GFPG GD G KG+K GDPG+ G+ G G G PG PG Sbjct: 525 --PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG------- 575 Query: 646 LTFIDMEG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRF---GVNSSDVPGPAGL 701 ++G G G+L AL G +G GPPG PG PG PG G G PG G Sbjct: 576 -----VKGLPGPKGEL-ALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGT 629 Query: 702 PGVPGREGPPG-------------FPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKG 748 GVPG GPPG PG PGPPGPPG GP G G GSLG+ G PG G Sbjct: 630 QGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPG 689 Query: 749 SKGA--------PGPAGARGESGLAGAPGPAGPPGPPGPPGPPG-PGLPAGFDDME---- 795 G PGP G +G+ G G G G PG G PG PG PGLP + Sbjct: 690 PDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMP 749 Query: 796 -GSGGPFWSTARSADGPQGP---PGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGR- 850 G G P + R G G PGLPGL G PG GL G +G+ G G PG G PGR Sbjct: 750 GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809 Query: 851 ----------EGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQ-- 898 G+ G +G +G RG G KGDPG G+ + G PG G PG + E Sbjct: 810 IEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGP 869 Query: 899 --------DGSVLSVPGPEGRPGFAGFP---GPAGPKGNLGS------------KGERGS 935 + +L PG +G G GFP GP GP GN G+ KG+RG+ Sbjct: 870 LGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929 Query: 936 PGPKGEKGEPGSIFSPD--------------GGALGPAQKGAKGEP------GFRGPPGP 975 PG KGE+G+ G+ + G A P +KG +G P G +G PGP Sbjct: 930 PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989 Query: 976 YGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPG-------DASLGF-GMRGMPGPPGPPGP 1027 G PG +G++G G PG PG+ G+ G G G +LGF G G PG PG G Sbjct: 990 AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049 Query: 1028 PGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQF------PFDF 1081 G G P Y +E +RPGPPG G+ G PG G KGE+G PGPPG Sbjct: 1050 QGDKGEPGY-----SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPG 1104 Query: 1082 LQLEAEMKGEKGDRGDAGQK---------GERGEPGGGGFFGS-------------SLPG 1119 + G+ G GD G K G RG PG GF GS +PG Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG 1164 Query: 1120 PPG----------PPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-IGYEGRQGPPGPPG 1168 P G PPGPRG PG G KG+ RG PG PG G G +G G +GP G G Sbjct: 1165 PAGEKGETGLLRAPPGPRGNPGAQGAKGD--RGAPGFPGLPGRKGAMGDAGPRGPTGIEG 1222 Query: 1169 PPGPPSFPGP-------HRQTISVPGPPGPPGPPGPPGT 1200 PGPP PG +R G PG PGPPGPPG+ Sbjct: 1223 FPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGS 1261 Score = 470 bits (1209), Expect = e-132 Identities = 340/890 (38%), Positives = 403/890 (45%), Gaps = 195/890 (21%) Query: 489 GAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSPCLPGP- 545 G + LPG + G G + G GL G G PG+PG PG GP G +PG Sbjct: 67 GPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCS 126 Query: 546 --------PGLPCPVSPLG-PAGPALQTVPGPQGPP-----------GPPGRDGTPGRDG 585 PGLP LG P P + G +G P G PG G PG G Sbjct: 127 GSKGEQGFPGLP---GTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQG 183 Query: 586 EPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPG---VGERGPPGPQGPPGPPGPSFR 642 PG PG G G GP GF G PG +GP+G KG G +G +G G +G GPPGP Sbjct: 184 LPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGP--- 240 Query: 643 HDKLTFIDMEGSGFGGDLEALRGPRGF---PGPPGP--------------PGVPGLPGEP 685 + + G DL+ +G +G PGPPGP PG PGL G+P Sbjct: 241 -PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKP 299 Query: 686 GRFGV----NSSDVPGPAGLPGVPGRE---------GPPGF---------------PGLP 717 G+ GV S V G G PG+ G + GPPGF G P Sbjct: 300 GKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTP 359 Query: 718 GPPGP-----------------------PGREGPPGRTGQKGSLGEAGAPGHKGSKGAPG 754 GPPGP PG G PG G KGS GE G PG K + G PG Sbjct: 360 GPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGTPG 418 Query: 755 PAGARGESGLAGAPGPAGPP-------GPPGPPGPPG----PGLPAGFDDMEGSGGPFWS 803 G G GL G+PGP GPP GPPG G PG PG+P G D +G G + Sbjct: 419 SPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIP-GVDGPKGEPGLLCT 477 Query: 804 TARSADGPQGPPGLPGLKGDPGVP------GLPGAKGEVGADGVPGFPGLPGREGIAGPQ 857 GP G PGLPGL G G+P GL G+ G G G+PGFPG PG +G G + Sbjct: 478 QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK 537 Query: 858 GPK-------------GDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVL 903 G K GD G RG+ G G DG+ G PG+ G PGP G + E+ Sbjct: 538 GEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ-- 595 Query: 904 SVPGPEGRPGFAGFPGPAGPKGN-----------LGSKGERGSPGPKGEKGEPG--SIFS 950 GP G PG G PGPAGP G G++G G+PGP GE G G S+ + Sbjct: 596 ---GPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652 Query: 951 PDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGL--------KGE 1002 P G GP G G PG +GPPG G G G+ G PG G PG+ G+ KG+ Sbjct: 653 PVPGPPGP--PGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGD 710 Query: 1003 KGEPG-DASLG----FGMRGMPGPPGPPGP--------PGPPGTPVY-----DSNVFAES 1044 +G PG SLG G G+PG PG PG PG PGTP + +S E Sbjct: 711 QGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEI 770 Query: 1045 SRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAE--------MKGEKGDRG 1096 PG PGLPG G G G +G+ G PGPPG+ +E + G KG +G Sbjct: 771 GLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQG 830 Query: 1097 DAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-- 1154 G+ G +G+PG G S PG G PG G+ G GP G+ RG PG PG GPPG Sbjct: 831 RRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ--RGYPGNPGILGPPGED 888 Query: 1155 --IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1202 IG G G GPPGPPG P PG R + +PG G G PG G G Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGTPG-QRGSPGIPGVKGQRGTPGAKGEQG 937 Score = 464 bits (1193), Expect = e-130 Identities = 352/942 (37%), Positives = 404/942 (42%), Gaps = 223/942 (23%) Query: 447 GAALKPRLPAPPPVTTP-PLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGS 505 G + P LP P T P L G S+ E+ +LG +PG+ G Sbjct: 100 GFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLP-GTLGYPGIPGAA------GL 152 Query: 506 VRTPGGRVKEGGLK-GQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP------------- 551 G KE ++ KG+PG+PG PG G PG P PGP G P P Sbjct: 153 KGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPR 212 Query: 552 ----------------------VSPLGPAGPALQTVPGPQ---------------GPPGP 574 P GP G + T+ GP G PGP Sbjct: 213 GPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGP 272 Query: 575 PGRDGTPGRD-----GEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV----GER 625 PG G PG G PGDPG GKPG G GFPG+ G KG++G PG+ G + Sbjct: 273 PGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEG---VKGNRGFPGLMGEDGIK 329 Query: 626 GPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEP 685 G G GPPG GP+ +D T+ + G G GPRG GP GP G PG+PG P Sbjct: 330 GQKGDIGPPGFRGPTEYYD--TYQEKGDEGTPGP----PGPRGARGPQGPSGPPGVPGSP 383 Query: 686 GRFGVNSSDVPGPAGL-----------------PGVPGREGPPGFPGLPGPPGPPG---- 724 G PG GL PG PG G PG PG PGPPGPPG Sbjct: 384 GSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVF 443 Query: 725 REGPPGRTGQKGSLGEAGAPGHKGSKGAPGPA-----------------GARGESGLAGA 767 R+GPPG G G LG G PG G KG PG G G G+ G Sbjct: 444 RKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGR 503 Query: 768 PGPAGPPGPPGPPGPPG-PGLPAGFDDMEGSGGPFWSTARSA--DGPQGPPGLPGLKGDP 824 G AG G PG PG G PG P GF +G G + +G G PG PGL+G P Sbjct: 504 QGAAGLKGSPGSPGNTGLPGFP-GFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQP 562 Query: 825 G------------VPGLPGAKGEV------GADGVPGFPGLPGREGIAGPQGPKGDRGSR 866 G V GLPG KGE+ G G PG PG PG G AGP GP G Sbjct: 563 GRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG----Y 618 Query: 867 GEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKG 925 G +G+PG G G PG PGPPG GP +S VPGP G PG G PGP GP G Sbjct: 619 GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST----PVPGPPGPPGPPGHPGPQGPPG 674 Query: 926 ---NLGSKGERGSPGPKGEKGEPGSIFSPDGGALG----PAQKGAKGEPGFRGPPGPYGR 978 +LG G+ G PGP GE G PG F G G P KG+ G PG G PG G+ Sbjct: 675 IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGK 734 Query: 979 PGY---KGE--IGFPGRPGRPGMNGLKGEKGEPGDASLGF--------------GMRGMP 1019 PG KGE + PG PG PG G +G GE G+ L G RG P Sbjct: 735 PGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDP 794 Query: 1020 GPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPF 1079 G PGPPG GPPG + E R G GLPG G G +G +G+ GP G PG Sbjct: 795 GQPGPPGEQGPPGRCI-------EGPR-GAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGL 846 Query: 1080 DFLQLEAEM--KGEKGDRGDAGQKGERGEPGGGGFFGS-------------------SLP 1118 D E G G +G+ G G+RG PG G G P Sbjct: 847 DRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPP 906 Query: 1119 GPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI----------------GYEGRQG 1162 G PG PG RG PGIPG KG+ RG PG G QG G G +G G Sbjct: 907 GNPGTPGQRGSPGIPGVKGQ--RGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAG 964 Query: 1163 PPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGAS 1204 PG G G P PG + G PGP GPPGP G +G++ Sbjct: 965 NPGEKGNRGVPGMPGLK----GLKGLPGPAGPPGPRGDLGST 1002 Score = 458 bits (1178), Expect = e-128 Identities = 322/776 (41%), Positives = 365/776 (47%), Gaps = 129/776 (16%) Query: 517 GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPG 576 G KG+KGE G PGPPG G G GP GLP P P G G +PG G G G Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKG---FTGPEGLPGPQGPKGFPG-----LPGLTGSKGVRG 94 Query: 577 RDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPG 635 G PG G PG PG PG+TGP G G PG G KG++G PG+ G G PG G G Sbjct: 95 ISGLPGFSGSPGLPGT---PGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAG 151 Query: 636 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 695 G K I+++ G G L GP+G PGPPG PG G PG PG FG + Sbjct: 152 LKGQKGAPAKEEDIELDAKGDPG-LPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMG 210 Query: 696 P-GPAGLPG--VPGREGPPGFPGLPGPPGPPGR-----EGPPGRT---GQKGSLGEAGAP 744 P GP G G V G +G G GL GPPGPPG GP RT G+KG G G P Sbjct: 211 PRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEP 270 Query: 745 GHKGSKGAPGPA-----GARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGG 799 G G G PG + GA G+ GL G PG G PG PG G G GF + G G Sbjct: 271 GPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN---RGFPGLMGEDG 327 Query: 800 PFWSTARSADGPQGPPGLPGL---------KGDPGVPGLPG---AKGEVGADGVPGFPGL 847 + G GPPG G KGD G PG PG A+G G G PG PG Sbjct: 328 -----IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGS 382 Query: 848 PG--REGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSV 905 PG R G+ G G G +GS+GE+G PGKD +G PG PG G PG + Sbjct: 383 PGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPG-----------LPGS 431 Query: 906 PGPEGRPGFAGF-PGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFS-------PDGGALG 957 PGP G PG F GP G G G G G PG G KGEPG + + P G Sbjct: 432 PGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGL 491 Query: 958 PAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNG---LKGEKGE--------- 1005 P G KG PG +G G G PG G G PG PG PG G LKGEKGE Sbjct: 492 PGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVG 551 Query: 1006 -PGDASLGF-----GMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPP 1059 PGD L G+ G+PG PG G PGP G + + E GPPG PG+ G P Sbjct: 552 VPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKG----ELALSGEKGDQGPPGDPGSPGSP 607 Query: 1060 GPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPG 1119 GP GP GPPG P Q E ++G +G G G GE G P G + +PG Sbjct: 608 GP------AGPAGPPGYGP----QGEPGLQGTQGVPGAPGPPGEAG-PRGELSVSTPVPG 656 Query: 1120 PPGPPGPRGYPGIPGPKGESIR----GQPGPPGPQGPPGIGYEGRQGPPGP--------- 1166 PPGPPGP G+PG GP G G PG PGP G PGI G GPPGP Sbjct: 657 PPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGT 716 Query: 1167 ------------PGPPGPPSFPGPHRQ-TISVPGPPGPPGPPGPPGTMGASSGVRL 1209 PG PG P PG + +++PG PG PG PG G G + L Sbjct: 717 KGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGL 772 Score = 404 bits (1038), Expect = e-112 Identities = 289/717 (40%), Positives = 332/717 (46%), Gaps = 161/717 (22%) Query: 616 DKG----DPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPG 671 DKG D GE+G G GPPG PG GF GP G PG Sbjct: 35 DKGQCFCDGAKGEKGEKGFPGPPGSPGQK--------------GF-------TGPEGLPG 73 Query: 672 PPGPPGVPGLPGEPGRFGVNS-SDVPG---PAGLPGVPGREGPPGFPGLPGPPGPPGREG 727 P GP G PGLPG G GV S +PG GLPG PG GP G G+PG G G +G Sbjct: 74 PQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQG 133 Query: 728 PPGRTGQKGSLGEAGAPGHKGSKGAPGPA-----GARGESGLAGAPGPAGPPGPPGPPGP 782 PG G G G GA G KG KGAP A+G+ GL GAPGP G PGPPG PGP Sbjct: 134 FPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGP 193 Query: 783 PGPGLPAGFDDMEGSGGPFWSTARSAD---------------GPQGPPG----------- 816 GP P GF G+ GP + GP GPPG Sbjct: 194 VGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDN 253 Query: 817 ---LPGLKGDPGVPGLPGAKG-----------EVGADGVPGFPGLPGREGIAGPQGPKGD 862 L G KGD G G PG G E GA G PG G PG++G+ G G +G Sbjct: 254 RTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGV 313 Query: 863 RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSE-QDGSVLSVPGPEGRPGFAGFPGP 920 +G+RG G G+DG+ GQ G GPPG GP Y Q+ PGP G G G GP Sbjct: 314 KGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGP 373 Query: 921 AGPKGNLGSKGE-----RGSPGPKGEKGEPGSIFSPDGGALG----PAQKGAKGEPGFRG 971 +GP G GS G RG+PG G KG G P A+G P G+ G PG G Sbjct: 374 SGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPG 433 Query: 972 PPGPYG----RPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLG--------------- 1012 PPGP G R G G+ G PG G PG+ G+ G KGEPG Sbjct: 434 PPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493 Query: 1013 -FGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE---- 1067 G++G+PG G G G PG+P + PG PG PG QG PG KG KGE Sbjct: 494 LHGVKGIPGRQGAAGLKGSPGSP-------GNTGLPGFPGFPGAQGDPGLKGEKGETLQP 546 Query: 1068 ---VGPPGPPG------QFPFDFLQLEAEMKGEKGDRGD---AGQKGERGEPGGGGFFGS 1115 VG PG PG + D + +KG G +G+ +G+KG++G PG G GS Sbjct: 547 EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606 Query: 1116 SLPGPPGPPGPRGY--------------PGIPGPKGES-IRGQ-------PGPPGPQGPP 1153 PGP GP GP GY PG PGP GE+ RG+ PGPPGP GPP Sbjct: 607 --PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664 Query: 1154 GIGYEGRQGPPGPP---GPPGPPSFPGPHRQT----ISVPGPPGPPGPPGPPGTMGA 1203 G + G QGPPG P G G P PGP + I PGPPGP G G PGT G+ Sbjct: 665 G--HPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719 Score = 398 bits (1022), Expect = e-110 Identities = 276/703 (39%), Positives = 313/703 (44%), Gaps = 142/703 (20%) Query: 452 PRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGG 511 P P PP PP G E R GAQ LPG + + G G Sbjct: 794 PGQPGPPGEQGPP---GRCIEGPR-------------GAQGLPGLNGLKGQQGRRGKTGP 837 Query: 512 RVKEG-------GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQT 564 + G G G+ G PG+PG G GP G PG PG+ P G G + Sbjct: 838 KGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIG--MMG 895 Query: 565 VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPK------GDKG 618 PG GPPGPPG GTPG+ G PG PG G+ G G +G G G+ GP GDKG Sbjct: 896 FPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKG 955 Query: 619 DPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP----- 672 +PG+ G G PG +G G PG G G L+ L GP G PGP Sbjct: 956 EPGLKGFAGNPGEKGNRGVPGMP--------------GLKG-LKGLPGPAGPPGPRGDLG 1000 Query: 673 ----PGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGL------------ 716 PG PG+ G+PG G G+ S G G G PGR G PG PG+ Sbjct: 1001 STGNPGEPGLRGIPGSMGNMGMPGSK--GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGY 1058 Query: 717 -----PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPA 771 PGPPGP G G PG G+KG +G+ G PGH G G G G+ G GL G PGP Sbjct: 1059 SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPH 1118 Query: 772 GPPG---------PPGPPGPPG-PGLPAGFDDMEGSGGPFWSTA-RSADGPQGPPGLPG- 819 G G PPG GPPG PG P GS GP + DG GP G G Sbjct: 1119 GDLGFKGIKGLLGPPGIRGPPGLPGFP-------GSPGPMGIRGDQGRDGIPGPAGEKGE 1171 Query: 820 ---LKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG 876 L+ PG G PGA+G G G PGFPGLPGR+G G GP+G G G G PG G Sbjct: 1172 TGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPG 1231 Query: 877 V---------------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPA 921 G PG PGPPGPPG V + D + PGP+G PG AG Sbjct: 1232 AIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG---DM 1288 Query: 922 GPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGY 981 GP G LG+ G G PGP+G+ G G P KG KG PGF G GP G G Sbjct: 1289 GPPGRLGAPGTPGLPGPRGDPGFQGF----------PGVKGEKGNPGFLGSIGPPGPIGP 1338 Query: 982 KGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVF 1041 KG G G PG + L G G PG GM+G PGPPGPPG GP G Sbjct: 1339 KGPPGVRGDPGTLKIISLPGSPGPPGTPGEP-GMQGEPGPPGPPGNLGPCG--------- 1388 Query: 1042 AESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQL 1084 P G PG G PG G GE G G G+ F QL Sbjct: 1389 -------PRGKPGKDGKPGTPGPAGEKGNKGSKGEPESLFHQL 1424 Score = 327 bits (839), Expect = 4e-89 Identities = 229/609 (37%), Positives = 272/609 (44%), Gaps = 112/609 (18%) Query: 421 GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 480 G D G G++GS + E G + P P + PP G + Sbjct: 845 GLDRSGFPGETGSPGIPGHQ---GEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIG 901 Query: 481 EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGG-----------LKGQKGEPGV-- 527 + G GS + G TPG + ++G + G KGEPG+ Sbjct: 902 PPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKG 961 Query: 528 ----PGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG----------PALQTVPGPQGPPG 573 PG G G PG P L G GLP P P GP G P L+ +PG G G Sbjct: 962 FAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMG 1021 Query: 574 PPGRDGT------PGRDGEPGDPGEDG--------------KPGDTGPQGFPGTPGDVGP 613 PG G PGR G PG PG G +PG GP G PG PGD+G Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGK 1081 Query: 614 KGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP 672 KG+ G PG G GP GP+G PG PG K G GDL +G +G GP Sbjct: 1082 KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK--------PGPHGDL-GFKGIKGLLGP 1132 Query: 673 PG---PPGVPGLPGEPGRFGVNSSD----VPGPAGLPGVPGR----EGPPGFPGLPGPPG 721 PG PPG+PG PG PG G+ +PGPAG G G GP G PG G G Sbjct: 1133 PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKG 1192 Query: 722 PPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARG-----ESGLAGAPGPAGPPGP 776 G G PG G+KG++G+AG G G +G PGP G G ++G G PG G PG Sbjct: 1193 DRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGA 1252 Query: 777 PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGL------PGLKGDPGVPGLP 830 PGPPGPPG + D G P GP+GPPG PG G PG PGLP Sbjct: 1253 PGPPGPPGSHVIGIKGDKGSMGHP---------GPKGPPGTAGDMGPPGRLGAPGTPGLP 1303 Query: 831 GAKGEVGADGVPGFPGL---PGREGIAGPQGPKGDRGSRGEKGDPGK-DGVGQPGLPGPP 886 G +G+ G G PG G PG G GP GP G +G G +GDPG + PG PGPP Sbjct: 1304 GPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPP 1363 Query: 887 GPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPG---PAGPKGNLGSKGERGSPGPKGEKG 943 G PG PG +G PG G PG P GP+G G G+ G+PGP GEKG Sbjct: 1364 GTPGE--------------PGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409 Query: 944 EPGSIFSPD 952 GS P+ Sbjct: 1410 NKGSKGEPE 1418 Score = 276 bits (706), Expect = 1e-73 Identities = 201/508 (39%), Positives = 230/508 (45%), Gaps = 106/508 (20%) Query: 747 KGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTAR 806 KG G G +GE G G PG G G GP G PGP P GF + G G Sbjct: 36 KGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTG------- 88 Query: 807 SADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPG---------FPGLP---GREGIA 854 + G +G GLPG G PG+PG PG G G GVPG FPGLP G GI Sbjct: 89 -SKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIP 147 Query: 855 GPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGF 914 G G KG +G+ ++ D D G PGLPG PGP+G PG Sbjct: 148 GAAGLKGQKGAPAKEEDIELDAKGDPGLPG--------------------APGPQGLPGP 187 Query: 915 AGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPG 974 GFPGP GP G G G G+ GP+G KG G +G KG +G G GPPG Sbjct: 188 PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGE------RVIG--HKGERGVKGLTGPPG 239 Query: 975 PYGR--------------PGYKGEIGFPGRPGRPGMNGLKGE-----KGEPGDASLGFGM 1015 P G G KG+ G G PG PG +GL GE KG PGD G+ Sbjct: 240 PPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDP----GL 295 Query: 1016 RGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPG 1075 +G PG G PG PG G G G PG G G KG KG++GPPG G Sbjct: 296 QGKPGKDGVPGFPGSEGVK-------------GNRGFPGLMGEDGIKGQKGDIGPPGFRG 342 Query: 1076 QFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGP--PGPRGYPGIP 1133 P ++ E KG++G G G +G RG G G G +PG PG PG RG PG P Sbjct: 343 --PTEYYDTYQE-KGDEGTPGPPGPRGARGPQGPSGPPG--VPGSPGSSRPGLRGAPGWP 397 Query: 1134 GPKG-ESIRGQPGPP--GPQGPPGI-GYEGRQGPPGPPGPPGPPSF----PGPHRQTISV 1185 G KG + RG+PG G G PG G G G PGPPGPPG F PG H Sbjct: 398 GLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH------ 451 Query: 1186 PGPPGPPGPPGPPGTMGASSGVRLWATR 1213 G PG G PG PG G L T+ Sbjct: 452 -GLPGYLGSPGIPGVDGPKGEPGLLCTQ 478 Score = 168 bits (426), Expect = 3e-41 Identities = 118/312 (37%), Positives = 134/312 (42%), Gaps = 72/312 (23%) Query: 946 GSIFSPDGGALGPAQKGAKGEPGFRGPP---------GPYGRPGYKGEIGFPGRPGRPGM 996 G + G KG KGE GF GPP GP G PG +G GFPG PG G Sbjct: 30 GCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGS 89 Query: 997 NGLKGEKGEPGDASLGFGMRGMPGPPGPPGP------------------PGPPGT----- 1033 G++G G PG + G G+PG PG GP PG PGT Sbjct: 90 KGVRGISGLPGFS----GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145 Query: 1034 -------------PVYDSNVFAES-SRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPF 1079 P + ++ ++ PG PG PG QG PGP G G VGPPGPPG F F Sbjct: 146 IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205 Query: 1080 DFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPP--------GPRGYPG 1131 KG G+R G KGERG G L GPPGPP GP Sbjct: 206 PGAMGPRGPKGHMGER-VIGHKGERGVKG--------LTGPPGPPGTVIVTLTGPDNRTD 256 Query: 1132 IPGPKGE-SIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPG 1190 + G KG+ G+PGPPGP G PG Y +G PG PG G P G PG G Sbjct: 257 LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDG----VPGFPGSEG 312 Query: 1191 PPGPPGPPGTMG 1202 G G PG MG Sbjct: 313 VKGNRGFPGLMG 324 Score = 34.7 bits (78), Expect = 0.72 Identities = 33/112 (29%), Positives = 41/112 (36%), Gaps = 11/112 (9%) Query: 150 GPLALAGPSSTPQENGTTLWPSRGIPSSPG--AHTTEAGTLPAPTPSPPSLGRPWAP-LT 206 GP AGP + L ++G+P +PG G L TP P G P P Sbjct: 608 GPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHP 667 Query: 207 GPSVPPPSSERISEEVGLLQLLGDPP-PQQVTQTDDPDVGLAYVFGPDANSG 257 GP PP G L GDP P + P +G GP + G Sbjct: 668 GPQGPPGIP-------GSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQG 712 >gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo sapiens] Length = 1494 Score = 512 bits (1318), Expect = e-144 Identities = 357/880 (40%), Positives = 410/880 (46%), Gaps = 160/880 (18%) Query: 426 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 485 G GD G LR + G +P P V P G E + S E +Q Sbjct: 551 GVPGDPG---------LRGQPGRKGLDGIPGTPGVKGLP---GPKGELALSGEKGDQGPP 598 Query: 486 ASLGAQTLPGSDSVSTWDGSVRTPG-GRVKEGGLKGQKGEPGVPGPPGRAGPPG----SP 540 G+ PG G PG G E GL+G +G PG PGPPG AGP G S Sbjct: 599 GDPGSPGSPGPA------GPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652 Query: 541 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGR------DGTPGRDGEPGDPGED- 593 +PGPPG P GP G PGPQGPPG PG G PG DGEPG PG Sbjct: 653 PVPGPPGPP------GPPGH-----PGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF 701 Query: 594 -GKPGDTGPQGFPGT---------------PGDVGPKGDKGDPGVGERGPPGPQGPPGPP 637 G PG G QGFPGT PG G G KG+P V G PG G PG Sbjct: 702 PGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGER 761 Query: 638 GPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPG 697 G S H ++ + G E L GPRG PG PGPPG G PG + +PG Sbjct: 762 GNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPG 821 Query: 698 PAGLPGVPGREG---PPGFPGLPG--PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA 752 GL G GR G P G PG+PG G PG G PG G +G +G G G+ G+ G Sbjct: 822 LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGI 881 Query: 753 PGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGLPAGFDDMEGSGGPFWSTARSA 808 GP G G G+ G PG GPPGPPG PG PG PG+P G G+ G A+ Sbjct: 882 LGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIP-GVKGQRGTPG-----AKGE 935 Query: 809 DGPQGPPG------LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGD 862 G +G PG + G KG+PG+ G G GE G GVPG PGL G +G+ GP GP G Sbjct: 936 QGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGP 995 Query: 863 RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGF---- 917 RG G G+PG+ G+ G PG G G PG S+ L PG GRPG G Sbjct: 996 RGDLGSTGNPGEPGLRGIPGSMGNMGMPG-----SKGKRGTLGFPGRAGRPGLPGIHGLQ 1050 Query: 918 -------------PGPAGPKGN------LGSKGERGSPGPKGE------KGEPGSIFSPD 952 PGP GP G+ +G KGE G PGP G +G PGS SP Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110 Query: 953 -GGALGP-------AQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG 1004 G GP KG G PG RGPPG G PG G +G G GR G+ G GEKG Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170 Query: 1005 EPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR-----------PGPPGLP 1053 E G G RG PG G G G PG P A PGPPGLP Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230 Query: 1054 G--------NQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERG 1105 G N+GPPG +G+ G GPPGPPG + + G KGD+G G G +G Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPG----------SHVIGIKGDKGSMGHPGPKG 1280 Query: 1106 EPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE-SIRGQPGPPGPQGPPGIGYEGRQGPP 1164 PG G G PPG G G PG+PGP+G+ +G PG G +G PG + G GPP Sbjct: 1281 PPGTAGDMG-----PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG--FLGSIGPP 1333 Query: 1165 GPPGPPGPPSFPGPHR--QTISVPGPPGPPGPPGPPGTMG 1202 GP GP GPP G + IS+PG PGPPG PG PG G Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373 Score = 480 bits (1235), Expect = e-135 Identities = 351/939 (37%), Positives = 415/939 (44%), Gaps = 186/939 (19%) Query: 423 DSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQ 482 D+ GD G+ R G + P +P P + P L G + + E Sbjct: 348 DTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERG 407 Query: 483 TTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCL 542 A PGS + G +PG G + +KG PG G PG G PG P + Sbjct: 408 RP--GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGV 465 Query: 543 PGP---PGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT 599 GP PGL C P P P L +PG G G PGR G G G PG PG G PG Sbjct: 466 DGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGF- 524 Query: 600 GPQGFPGTPGDVGPKGDK-------------GDPGV-GERGPPGPQGPPGPPGPSFRHDK 645 GFPG GD G KG+K GDPG+ G+ G G G PG PG Sbjct: 525 --PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG------- 575 Query: 646 LTFIDMEG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRF---GVNSSDVPGPAGL 701 ++G G G+L AL G +G GPPG PG PG PG G G PG G Sbjct: 576 -----VKGLPGPKGEL-ALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGT 629 Query: 702 PGVPGREGPPG-------------FPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKG 748 GVPG GPPG PG PGPPGPPG GP G G GSLG+ G PG G Sbjct: 630 QGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPG 689 Query: 749 SKGA--------PGPAGARGESGLAGAPGPAGPPGPPGPPGPPG-PGLPAGFDDME---- 795 G PGP G +G+ G G G G PG G PG PG PGLP + Sbjct: 690 PDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMP 749 Query: 796 -GSGGPFWSTARSADGPQGP---PGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGR- 850 G G P + R G G PGLPGL G PG GL G +G+ G G PG G PGR Sbjct: 750 GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809 Query: 851 ----------EGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQ-- 898 G+ G +G +G RG G KGDPG G+ + G PG G PG + E Sbjct: 810 IEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGP 869 Query: 899 --------DGSVLSVPGPEGRPGFAGFP---GPAGPKGNLGS------------KGERGS 935 + +L PG +G G GFP GP GP GN G+ KG+RG+ Sbjct: 870 LGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929 Query: 936 PGPKGEKGEPGSIFSPD--------------GGALGPAQKGAKGEP------GFRGPPGP 975 PG KGE+G+ G+ + G A P +KG +G P G +G PGP Sbjct: 930 PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989 Query: 976 YGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPG-------DASLGF-GMRGMPGPPGPPGP 1027 G PG +G++G G PG PG+ G+ G G G +LGF G G PG PG G Sbjct: 990 AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049 Query: 1028 PGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQF------PFDF 1081 G G P Y +E +RPGPPG G+ G PG G KGE+G PGPPG Sbjct: 1050 QGDKGEPGY-----SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPG 1104 Query: 1082 LQLEAEMKGEKGDRGDAGQK---------GERGEPGGGGFFGS-------------SLPG 1119 + G+ G GD G K G RG PG GF GS +PG Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG 1164 Query: 1120 PPG----------PPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-IGYEGRQGPPGPPG 1168 P G PPGPRG PG G KG+ RG PG PG G G +G G +GP G G Sbjct: 1165 PAGEKGETGLLRAPPGPRGNPGAQGAKGD--RGAPGFPGLPGRKGAMGDAGPRGPTGIEG 1222 Query: 1169 PPGPPSFPGP-------HRQTISVPGPPGPPGPPGPPGT 1200 PGPP PG +R G PG PGPPGPPG+ Sbjct: 1223 FPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGS 1261 Score = 470 bits (1209), Expect = e-132 Identities = 340/890 (38%), Positives = 403/890 (45%), Gaps = 195/890 (21%) Query: 489 GAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSPCLPGP- 545 G + LPG + G G + G GL G G PG+PG PG GP G +PG Sbjct: 67 GPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCS 126 Query: 546 --------PGLPCPVSPLG-PAGPALQTVPGPQGPP-----------GPPGRDGTPGRDG 585 PGLP LG P P + G +G P G PG G PG G Sbjct: 127 GSKGEQGFPGLP---GTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQG 183 Query: 586 EPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPG---VGERGPPGPQGPPGPPGPSFR 642 PG PG G G GP GF G PG +GP+G KG G +G +G G +G GPPGP Sbjct: 184 LPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGP--- 240 Query: 643 HDKLTFIDMEGSGFGGDLEALRGPRGF---PGPPGP--------------PGVPGLPGEP 685 + + G DL+ +G +G PGPPGP PG PGL G+P Sbjct: 241 -PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKP 299 Query: 686 GRFGV----NSSDVPGPAGLPGVPGRE---------GPPGF---------------PGLP 717 G+ GV S V G G PG+ G + GPPGF G P Sbjct: 300 GKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTP 359 Query: 718 GPPGP-----------------------PGREGPPGRTGQKGSLGEAGAPGHKGSKGAPG 754 GPPGP PG G PG G KGS GE G PG K + G PG Sbjct: 360 GPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGTPG 418 Query: 755 PAGARGESGLAGAPGPAGPP-------GPPGPPGPPG----PGLPAGFDDMEGSGGPFWS 803 G G GL G+PGP GPP GPPG G PG PG+P G D +G G + Sbjct: 419 SPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIP-GVDGPKGEPGLLCT 477 Query: 804 TARSADGPQGPPGLPGLKGDPGVP------GLPGAKGEVGADGVPGFPGLPGREGIAGPQ 857 GP G PGLPGL G G+P GL G+ G G G+PGFPG PG +G G + Sbjct: 478 QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK 537 Query: 858 GPK-------------GDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVL 903 G K GD G RG+ G G DG+ G PG+ G PGP G + E+ Sbjct: 538 GEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ-- 595 Query: 904 SVPGPEGRPGFAGFPGPAGPKGN-----------LGSKGERGSPGPKGEKGEPG--SIFS 950 GP G PG G PGPAGP G G++G G+PGP GE G G S+ + Sbjct: 596 ---GPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652 Query: 951 PDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGL--------KGE 1002 P G GP G G PG +GPPG G G G+ G PG G PG+ G+ KG+ Sbjct: 653 PVPGPPGP--PGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGD 710 Query: 1003 KGEPG-DASLG----FGMRGMPGPPGPPGP--------PGPPGTPVY-----DSNVFAES 1044 +G PG SLG G G+PG PG PG PG PGTP + +S E Sbjct: 711 QGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEI 770 Query: 1045 SRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAE--------MKGEKGDRG 1096 PG PGLPG G G G +G+ G PGPPG+ +E + G KG +G Sbjct: 771 GLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQG 830 Query: 1097 DAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-- 1154 G+ G +G+PG G S PG G PG G+ G GP G+ RG PG PG GPPG Sbjct: 831 RRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ--RGYPGNPGILGPPGED 888 Query: 1155 --IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1202 IG G G GPPGPPG P PG R + +PG G G PG G G Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGTPG-QRGSPGIPGVKGQRGTPGAKGEQG 937 Score = 454 bits (1168), Expect = e-127 Identities = 322/796 (40%), Positives = 364/796 (45%), Gaps = 144/796 (18%) Query: 517 GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP-ALQTVPGPQGPPGPP 575 G KG+KGE G PGPPG PG G P GP GP +PG G G Sbjct: 43 GAKGEKGEKGFPGPPGS---------PGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVR 93 Query: 576 GRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPP 634 G G PG G PG P G PG+TGP G G PG G KG++G PG+ G G PG G Sbjct: 94 GISGLPGFSGSPGLP---GTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAA 150 Query: 635 GPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSD 694 G G K I+++ G G L GP+G PGPPG PG G PG PG FG + Sbjct: 151 GLKGQKGAPAKEEDIELDAKGDPG-LPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM 209 Query: 695 VP-GPAGLPG--VPGREGPPGFPGLPGPPGPPGR-----EGPPGRT---GQKGSLGEAGA 743 P GP G G V G +G G GL GPPGPPG GP RT G+KG G G Sbjct: 210 GPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE 269 Query: 744 PGHKGSKGAPGPA-----GARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSG 798 PG G G PG + GA G+ GL G PG G PG PG G G GF + G Sbjct: 270 PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG---NRGFPGLMGED 326 Query: 799 GPFWSTARSADGPQGPPGLPG---------LKGDPGVPGLP---GAKGEVGADGVPGFPG 846 G + G GPPG G KGD G PG P GA+G G G PG PG Sbjct: 327 G-----IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPG 381 Query: 847 LPG--REGIAGPQGPKGDRGSRGEKGDPGKDGVGQ------------PGLPGPPGPPGPV 892 PG R G+ G G G +GS+GE+G PGKD +G PG PGPPGPPG + Sbjct: 382 SPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDI 441 Query: 893 VYVSEQDG----------------------------SVLSVPGPEGRPGFAGFPGPAGPK 924 V+ G +PGP G PG G G G Sbjct: 442 VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIP 501 Query: 925 GNLGSKGERGSPGPKGEKGEPGSIFSPDGGALG-PAQKGAKGEP-------GFRGPPGPY 976 G G+ G +GSPG G G PG F GA G P KG KGE G G PG Sbjct: 502 GRQGAAGLKGSPGSPGNTGLPG--FPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLR 559 Query: 977 GRPGYKGEIGFPGRPGRPGMNGLKGE---KGEPGDASLGFGMRGMPGPPGPPGPPGPPGT 1033 G+PG KG G PG PG G+ G KGE GE GD G G PG PG PGP GP G Sbjct: 560 GQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ----GPPGDPGSPGSPGPAGPAGP 615 Query: 1034 PVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEV-------GPPGPPGQFPFDFLQLEA 1086 P Y E G G+PG GPPG G +GE+ GPPGPPG Q Sbjct: 616 PGYGPQ--GEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPP 673 Query: 1087 EMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYP------GIPGPKGE-S 1139 + G G GD G G GEP G G PGPPGP G +G+P G PG GE Sbjct: 674 GIPGSLGKCGDPGLPGPDGEP---GIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPG 730 Query: 1140 IRGQPGPPGPQGPPGIGYEGRQGPPGPPGP------------PGPPSFPG-PHRQTISVP 1186 + G+PG PG +G P + G G PG PG PG P PG P + + Sbjct: 731 LPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNE--GLD 788 Query: 1187 GPPGPPGPPGPPGTMG 1202 GP G PG PGPPG G Sbjct: 789 GPRGDPGQPGPPGEQG 804 Score = 404 bits (1038), Expect = e-112 Identities = 289/717 (40%), Positives = 332/717 (46%), Gaps = 161/717 (22%) Query: 616 DKG----DPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPG 671 DKG D GE+G G GPPG PG GF GP G PG Sbjct: 35 DKGQCFCDGAKGEKGEKGFPGPPGSPGQK--------------GF-------TGPEGLPG 73 Query: 672 PPGPPGVPGLPGEPGRFGVNS-SDVPG---PAGLPGVPGREGPPGFPGLPGPPGPPGREG 727 P GP G PGLPG G GV S +PG GLPG PG GP G G+PG G G +G Sbjct: 74 PQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQG 133 Query: 728 PPGRTGQKGSLGEAGAPGHKGSKGAPGPA-----GARGESGLAGAPGPAGPPGPPGPPGP 782 PG G G G GA G KG KGAP A+G+ GL GAPGP G PGPPG PGP Sbjct: 134 FPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGP 193 Query: 783 PGPGLPAGFDDMEGSGGPFWSTARSAD---------------GPQGPPG----------- 816 GP P GF G+ GP + GP GPPG Sbjct: 194 VGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDN 253 Query: 817 ---LPGLKGDPGVPGLPGAKG-----------EVGADGVPGFPGLPGREGIAGPQGPKGD 862 L G KGD G G PG G E GA G PG G PG++G+ G G +G Sbjct: 254 RTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGV 313 Query: 863 RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSE-QDGSVLSVPGPEGRPGFAGFPGP 920 +G+RG G G+DG+ GQ G GPPG GP Y Q+ PGP G G G GP Sbjct: 314 KGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGP 373 Query: 921 AGPKGNLGSKGE-----RGSPGPKGEKGEPGSIFSPDGGALG----PAQKGAKGEPGFRG 971 +GP G GS G RG+PG G KG G P A+G P G+ G PG G Sbjct: 374 SGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPG 433 Query: 972 PPGPYG----RPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLG--------------- 1012 PPGP G R G G+ G PG G PG+ G+ G KGEPG Sbjct: 434 PPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493 Query: 1013 -FGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE---- 1067 G++G+PG G G G PG+P + PG PG PG QG PG KG KGE Sbjct: 494 LHGVKGIPGRQGAAGLKGSPGSP-------GNTGLPGFPGFPGAQGDPGLKGEKGETLQP 546 Query: 1068 ---VGPPGPPG------QFPFDFLQLEAEMKGEKGDRGD---AGQKGERGEPGGGGFFGS 1115 VG PG PG + D + +KG G +G+ +G+KG++G PG G GS Sbjct: 547 EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606 Query: 1116 SLPGPPGPPGPRGY--------------PGIPGPKGES-IRGQ-------PGPPGPQGPP 1153 PGP GP GP GY PG PGP GE+ RG+ PGPPGP GPP Sbjct: 607 --PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664 Query: 1154 GIGYEGRQGPPGPP---GPPGPPSFPGPHRQT----ISVPGPPGPPGPPGPPGTMGA 1203 G + G QGPPG P G G P PGP + I PGPPGP G G PGT G+ Sbjct: 665 G--HPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719 Score = 385 bits (990), Expect = e-106 Identities = 274/701 (39%), Positives = 309/701 (44%), Gaps = 147/701 (20%) Query: 452 PRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGG 511 P P PP PP G E R GAQ LPG + + G G Sbjct: 794 PGQPGPPGEQGPP---GRCIEGPR-------------GAQGLPGLNGLKGQQGRRGKTGP 837 Query: 512 RVKEG-------GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQT 564 + G G G+ G PG+PG G GP G PG PG+ P G G + Sbjct: 838 KGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIG--MMG 895 Query: 565 VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPK------GDKG 618 PG GPPGPPG GTPG+ G PG PG G+ G G +G G G+ GP GDKG Sbjct: 896 FPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKG 955 Query: 619 DPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP----- 672 +PG+ G G PG +G G PG G G L+ L GP G PGP Sbjct: 956 EPGLKGFAGNPGEKGNRGVPGMP--------------GLKG-LKGLPGPAGPPGPRGDLG 1000 Query: 673 ----PGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGL------------ 716 PG PG+ G+PG G G+ S G G G PGR G PG PG+ Sbjct: 1001 STGNPGEPGLRGIPGSMGNMGMPGSK--GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGY 1058 Query: 717 -----PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGP- 770 PGPPGP G G PG G+KG +G+ G PGH G G G G+ G GL G PGP Sbjct: 1059 SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPH 1118 Query: 771 -----------AGPPGPPGPPGPPG-PGLPA--------GFDDMEGSGGPFWSTA--RSA 808 GPPG GPPG PG PG P G D + G G T R+ Sbjct: 1119 GDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAP 1178 Query: 809 DGPQGPPGLPGLKGD---PGVPGLPGAKGEVG---------ADGVPGFPGLPGR--EGIA 854 GP+G PG G KGD PG PGLPG KG +G +G PG PGLPG G Sbjct: 1179 PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT 1238 Query: 855 GPQGPKGDRGSRGEKGDPGKDGV---------GQPGLPGPPGPPGPVVYVSEQDG----S 901 G +GP G RGS G G PG G G G PGP GPPG + Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPG 1298 Query: 902 VLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGAL----- 956 +PGP G PGF GFPG G KGN G G G PGP G KG PG D G L Sbjct: 1299 TPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG--VRGDPGTLKIISL 1356 Query: 957 --GPAQKGAKGEPGFRGPPGPYGRPGY---------KGEIGFPGRPGRPGMNGLKGEKGE 1005 P G GEPG +G PGP G PG G+ G PG PG G G KG KGE Sbjct: 1357 PGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGE 1416 Query: 1006 PGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR 1046 PG A G G+PG G G G P T VF S+ Sbjct: 1417 PGPA----GSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQ 1453 Score = 338 bits (868), Expect = 2e-92 Identities = 242/644 (37%), Positives = 286/644 (44%), Gaps = 119/644 (18%) Query: 421 GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 480 G D G G++GS + E G + P P + PP G + Sbjct: 845 GLDRSGFPGETGSPGIPGHQ---GEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIG 901 Query: 481 EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGG-----------LKGQKGEPGV-- 527 + G GS + G TPG + ++G + G KGEPG+ Sbjct: 902 PPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKG 961 Query: 528 ----PGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG----------PALQTVPGPQGPPG 573 PG G G PG P L G GLP P P GP G P L+ +PG G G Sbjct: 962 FAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMG 1021 Query: 574 PPGRDGT------PGRDGEPGDPGEDG--------------KPGDTGPQGFPGTPGDVGP 613 PG G PGR G PG PG G +PG GP G PG PGD+G Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGK 1081 Query: 614 KGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP 672 KG+ G PG G GP GP+G PG PG K G GDL +G +G GP Sbjct: 1082 KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK--------PGPHGDL-GFKGIKGLLGP 1132 Query: 673 PG---PPGVPGLPGEPGRFGVNSSD----VPGPAGLPGVPGR----EGPPGFPGLPGPPG 721 PG PPG+PG PG PG G+ +PGPAG G G GP G PG G G Sbjct: 1133 PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKG 1192 Query: 722 PPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARG-----ESGLAGAPGPAGPPGP 776 G G PG G+KG++G+AG G G +G PGP G G ++G G PG G PG Sbjct: 1193 DRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGA 1252 Query: 777 PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGL------PGLKGDPGVPGLP 830 PGPPGPPG + D G P GP+GPPG PG G PG PGLP Sbjct: 1253 PGPPGPPGSHVIGIKGDKGSMGHP---------GPKGPPGTAGDMGPPGRLGAPGTPGLP 1303 Query: 831 GAKGEVGADGVPGFPGL---PGREGIAGPQGPKGDRGSRGEKGDPGK-DGVGQPGLPGPP 886 G +G+ G G PG G PG G GP GP G +G G +GDPG + PG PGPP Sbjct: 1304 GPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPP 1363 Query: 887 GPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPG---PAGPKGNLGSKGERGSPGPKGEKG 943 G PG PG +G PG G PG P GP+G G G+ G+PGP GEKG Sbjct: 1364 GTPGE--------------PGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409 Query: 944 EPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGF 987 GS P GPA G+ G PG +G G G P GF Sbjct: 1410 NKGSKGEP-----GPA--GSDGLPGLKGKRGDSGSPATWTTRGF 1446 Score = 276 bits (706), Expect = 1e-73 Identities = 201/508 (39%), Positives = 230/508 (45%), Gaps = 106/508 (20%) Query: 747 KGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTAR 806 KG G G +GE G G PG G G GP G PGP P GF + G G Sbjct: 36 KGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTG------- 88 Query: 807 SADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPG---------FPGLP---GREGIA 854 + G +G GLPG G PG+PG PG G G GVPG FPGLP G GI Sbjct: 89 -SKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIP 147 Query: 855 GPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGF 914 G G KG +G+ ++ D D G PGLPG PGP+G PG Sbjct: 148 GAAGLKGQKGAPAKEEDIELDAKGDPGLPG--------------------APGPQGLPGP 187 Query: 915 AGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPG 974 GFPGP GP G G G G+ GP+G KG G +G KG +G G GPPG Sbjct: 188 PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGE------RVIG--HKGERGVKGLTGPPG 239 Query: 975 PYGR--------------PGYKGEIGFPGRPGRPGMNGLKGE-----KGEPGDASLGFGM 1015 P G G KG+ G G PG PG +GL GE KG PGD G+ Sbjct: 240 PPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDP----GL 295 Query: 1016 RGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPG 1075 +G PG G PG PG G G G PG G G KG KG++GPPG G Sbjct: 296 QGKPGKDGVPGFPGSEGVK-------------GNRGFPGLMGEDGIKGQKGDIGPPGFRG 342 Query: 1076 QFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGP--PGPRGYPGIP 1133 P ++ E KG++G G G +G RG G G G +PG PG PG RG PG P Sbjct: 343 --PTEYYDTYQE-KGDEGTPGPPGPRGARGPQGPSGPPG--VPGSPGSSRPGLRGAPGWP 397 Query: 1134 GPKG-ESIRGQPGPP--GPQGPPGI-GYEGRQGPPGPPGPPGPPSF----PGPHRQTISV 1185 G KG + RG+PG G G PG G G G PGPPGPPG F PG H Sbjct: 398 GLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH------ 451 Query: 1186 PGPPGPPGPPGPPGTMGASSGVRLWATR 1213 G PG G PG PG G L T+ Sbjct: 452 -GLPGYLGSPGIPGVDGPKGEPGLLCTQ 478 Score = 168 bits (426), Expect = 3e-41 Identities = 118/312 (37%), Positives = 134/312 (42%), Gaps = 72/312 (23%) Query: 946 GSIFSPDGGALGPAQKGAKGEPGFRGPP---------GPYGRPGYKGEIGFPGRPGRPGM 996 G + G KG KGE GF GPP GP G PG +G GFPG PG G Sbjct: 30 GCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGS 89 Query: 997 NGLKGEKGEPGDASLGFGMRGMPGPPGPPGP------------------PGPPGT----- 1033 G++G G PG + G G+PG PG GP PG PGT Sbjct: 90 KGVRGISGLPGFS----GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145 Query: 1034 -------------PVYDSNVFAES-SRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPF 1079 P + ++ ++ PG PG PG QG PGP G G VGPPGPPG F F Sbjct: 146 IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205 Query: 1080 DFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPP--------GPRGYPG 1131 KG G+R G KGERG G L GPPGPP GP Sbjct: 206 PGAMGPRGPKGHMGER-VIGHKGERGVKG--------LTGPPGPPGTVIVTLTGPDNRTD 256 Query: 1132 IPGPKGE-SIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPG 1190 + G KG+ G+PGPPGP G PG Y +G PG PG G P G PG G Sbjct: 257 LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDG----VPGFPGSEG 312 Query: 1191 PPGPPGPPGTMG 1202 G G PG MG Sbjct: 313 VKGNRGFPGLMG 324 Score = 34.7 bits (78), Expect = 0.72 Identities = 33/112 (29%), Positives = 41/112 (36%), Gaps = 11/112 (9%) Query: 150 GPLALAGPSSTPQENGTTLWPSRGIPSSPG--AHTTEAGTLPAPTPSPPSLGRPWAP-LT 206 GP AGP + L ++G+P +PG G L TP P G P P Sbjct: 608 GPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHP 667 Query: 207 GPSVPPPSSERISEEVGLLQLLGDPP-PQQVTQTDDPDVGLAYVFGPDANSG 257 GP PP G L GDP P + P +G GP + G Sbjct: 668 GPQGPPGIP-------GSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQG 712 >gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo sapiens] Length = 1637 Score = 512 bits (1318), Expect = e-144 Identities = 357/880 (40%), Positives = 410/880 (46%), Gaps = 160/880 (18%) Query: 426 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 485 G GD G LR + G +P P V P G E + S E +Q Sbjct: 551 GVPGDPG---------LRGQPGRKGLDGIPGTPGVKGLP---GPKGELALSGEKGDQGPP 598 Query: 486 ASLGAQTLPGSDSVSTWDGSVRTPG-GRVKEGGLKGQKGEPGVPGPPGRAGPPG----SP 540 G+ PG G PG G E GL+G +G PG PGPPG AGP G S Sbjct: 599 GDPGSPGSPGPA------GPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652 Query: 541 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGR------DGTPGRDGEPGDPGED- 593 +PGPPG P GP G PGPQGPPG PG G PG DGEPG PG Sbjct: 653 PVPGPPGPP------GPPGH-----PGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF 701 Query: 594 -GKPGDTGPQGFPGT---------------PGDVGPKGDKGDPGVGERGPPGPQGPPGPP 637 G PG G QGFPGT PG G G KG+P V G PG G PG Sbjct: 702 PGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGER 761 Query: 638 GPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPG 697 G S H ++ + G E L GPRG PG PGPPG G PG + +PG Sbjct: 762 GNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPG 821 Query: 698 PAGLPGVPGREG---PPGFPGLPG--PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA 752 GL G GR G P G PG+PG G PG G PG G +G +G G G+ G+ G Sbjct: 822 LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGI 881 Query: 753 PGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGLPAGFDDMEGSGGPFWSTARSA 808 GP G G G+ G PG GPPGPPG PG PG PG+P G G+ G A+ Sbjct: 882 LGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIP-GVKGQRGTPG-----AKGE 935 Query: 809 DGPQGPPG------LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGD 862 G +G PG + G KG+PG+ G G GE G GVPG PGL G +G+ GP GP G Sbjct: 936 QGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGP 995 Query: 863 RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGF---- 917 RG G G+PG+ G+ G PG G G PG S+ L PG GRPG G Sbjct: 996 RGDLGSTGNPGEPGLRGIPGSMGNMGMPG-----SKGKRGTLGFPGRAGRPGLPGIHGLQ 1050 Query: 918 -------------PGPAGPKGN------LGSKGERGSPGPKGE------KGEPGSIFSPD 952 PGP GP G+ +G KGE G PGP G +G PGS SP Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110 Query: 953 -GGALGP-------AQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG 1004 G GP KG G PG RGPPG G PG G +G G GR G+ G GEKG Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170 Query: 1005 EPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR-----------PGPPGLP 1053 E G G RG PG G G G PG P A PGPPGLP Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230 Query: 1054 G--------NQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERG 1105 G N+GPPG +G+ G GPPGPPG + + G KGD+G G G +G Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPG----------SHVIGIKGDKGSMGHPGPKG 1280 Query: 1106 EPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE-SIRGQPGPPGPQGPPGIGYEGRQGPP 1164 PG G G PPG G G PG+PGP+G+ +G PG G +G PG + G GPP Sbjct: 1281 PPGTAGDMG-----PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG--FLGSIGPP 1333 Query: 1165 GPPGPPGPPSFPGPHR--QTISVPGPPGPPGPPGPPGTMG 1202 GP GP GPP G + IS+PG PGPPG PG PG G Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373 Score = 480 bits (1235), Expect = e-135 Identities = 351/939 (37%), Positives = 415/939 (44%), Gaps = 186/939 (19%) Query: 423 DSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQ 482 D+ GD G+ R G + P +P P + P L G + + E Sbjct: 348 DTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERG 407 Query: 483 TTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCL 542 A PGS + G +PG G + +KG PG G PG G PG P + Sbjct: 408 RP--GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGV 465 Query: 543 PGP---PGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT 599 GP PGL C P P P L +PG G G PGR G G G PG PG G PG Sbjct: 466 DGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGF- 524 Query: 600 GPQGFPGTPGDVGPKGDK-------------GDPGV-GERGPPGPQGPPGPPGPSFRHDK 645 GFPG GD G KG+K GDPG+ G+ G G G PG PG Sbjct: 525 --PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG------- 575 Query: 646 LTFIDMEG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRF---GVNSSDVPGPAGL 701 ++G G G+L AL G +G GPPG PG PG PG G G PG G Sbjct: 576 -----VKGLPGPKGEL-ALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGT 629 Query: 702 PGVPGREGPPG-------------FPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKG 748 GVPG GPPG PG PGPPGPPG GP G G GSLG+ G PG G Sbjct: 630 QGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPG 689 Query: 749 SKGA--------PGPAGARGESGLAGAPGPAGPPGPPGPPGPPG-PGLPAGFDDME---- 795 G PGP G +G+ G G G G PG G PG PG PGLP + Sbjct: 690 PDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMP 749 Query: 796 -GSGGPFWSTARSADGPQGP---PGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGR- 850 G G P + R G G PGLPGL G PG GL G +G+ G G PG G PGR Sbjct: 750 GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809 Query: 851 ----------EGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQ-- 898 G+ G +G +G RG G KGDPG G+ + G PG G PG + E Sbjct: 810 IEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGP 869 Query: 899 --------DGSVLSVPGPEGRPGFAGFP---GPAGPKGNLGS------------KGERGS 935 + +L PG +G G GFP GP GP GN G+ KG+RG+ Sbjct: 870 LGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929 Query: 936 PGPKGEKGEPGSIFSPD--------------GGALGPAQKGAKGEP------GFRGPPGP 975 PG KGE+G+ G+ + G A P +KG +G P G +G PGP Sbjct: 930 PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989 Query: 976 YGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPG-------DASLGF-GMRGMPGPPGPPGP 1027 G PG +G++G G PG PG+ G+ G G G +LGF G G PG PG G Sbjct: 990 AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049 Query: 1028 PGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQF------PFDF 1081 G G P Y +E +RPGPPG G+ G PG G KGE+G PGPPG Sbjct: 1050 QGDKGEPGY-----SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPG 1104 Query: 1082 LQLEAEMKGEKGDRGDAGQK---------GERGEPGGGGFFGS-------------SLPG 1119 + G+ G GD G K G RG PG GF GS +PG Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG 1164 Query: 1120 PPG----------PPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-IGYEGRQGPPGPPG 1168 P G PPGPRG PG G KG+ RG PG PG G G +G G +GP G G Sbjct: 1165 PAGEKGETGLLRAPPGPRGNPGAQGAKGD--RGAPGFPGLPGRKGAMGDAGPRGPTGIEG 1222 Query: 1169 PPGPPSFPGP-------HRQTISVPGPPGPPGPPGPPGT 1200 PGPP PG +R G PG PGPPGPPG+ Sbjct: 1223 FPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGS 1261 Score = 470 bits (1209), Expect = e-132 Identities = 340/890 (38%), Positives = 403/890 (45%), Gaps = 195/890 (21%) Query: 489 GAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSPCLPGP- 545 G + LPG + G G + G GL G G PG+PG PG GP G +PG Sbjct: 67 GPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCS 126 Query: 546 --------PGLPCPVSPLG-PAGPALQTVPGPQGPP-----------GPPGRDGTPGRDG 585 PGLP LG P P + G +G P G PG G PG G Sbjct: 127 GSKGEQGFPGLP---GTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQG 183 Query: 586 EPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPG---VGERGPPGPQGPPGPPGPSFR 642 PG PG G G GP GF G PG +GP+G KG G +G +G G +G GPPGP Sbjct: 184 LPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGP--- 240 Query: 643 HDKLTFIDMEGSGFGGDLEALRGPRGF---PGPPGP--------------PGVPGLPGEP 685 + + G DL+ +G +G PGPPGP PG PGL G+P Sbjct: 241 -PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKP 299 Query: 686 GRFGV----NSSDVPGPAGLPGVPGRE---------GPPGF---------------PGLP 717 G+ GV S V G G PG+ G + GPPGF G P Sbjct: 300 GKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTP 359 Query: 718 GPPGP-----------------------PGREGPPGRTGQKGSLGEAGAPGHKGSKGAPG 754 GPPGP PG G PG G KGS GE G PG K + G PG Sbjct: 360 GPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGTPG 418 Query: 755 PAGARGESGLAGAPGPAGPP-------GPPGPPGPPG----PGLPAGFDDMEGSGGPFWS 803 G G GL G+PGP GPP GPPG G PG PG+P G D +G G + Sbjct: 419 SPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIP-GVDGPKGEPGLLCT 477 Query: 804 TARSADGPQGPPGLPGLKGDPGVP------GLPGAKGEVGADGVPGFPGLPGREGIAGPQ 857 GP G PGLPGL G G+P GL G+ G G G+PGFPG PG +G G + Sbjct: 478 QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK 537 Query: 858 GPK-------------GDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVL 903 G K GD G RG+ G G DG+ G PG+ G PGP G + E+ Sbjct: 538 GEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ-- 595 Query: 904 SVPGPEGRPGFAGFPGPAGPKGN-----------LGSKGERGSPGPKGEKGEPG--SIFS 950 GP G PG G PGPAGP G G++G G+PGP GE G G S+ + Sbjct: 596 ---GPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652 Query: 951 PDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGL--------KGE 1002 P G GP G G PG +GPPG G G G+ G PG G PG+ G+ KG+ Sbjct: 653 PVPGPPGP--PGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGD 710 Query: 1003 KGEPG-DASLG----FGMRGMPGPPGPPGP--------PGPPGTPVY-----DSNVFAES 1044 +G PG SLG G G+PG PG PG PG PGTP + +S E Sbjct: 711 QGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEI 770 Query: 1045 SRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAE--------MKGEKGDRG 1096 PG PGLPG G G G +G+ G PGPPG+ +E + G KG +G Sbjct: 771 GLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQG 830 Query: 1097 DAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-- 1154 G+ G +G+PG G S PG G PG G+ G GP G+ RG PG PG GPPG Sbjct: 831 RRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ--RGYPGNPGILGPPGED 888 Query: 1155 --IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1202 IG G G GPPGPPG P PG R + +PG G G PG G G Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGTPG-QRGSPGIPGVKGQRGTPGAKGEQG 937 Score = 454 bits (1168), Expect = e-127 Identities = 322/796 (40%), Positives = 364/796 (45%), Gaps = 144/796 (18%) Query: 517 GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP-ALQTVPGPQGPPGPP 575 G KG+KGE G PGPPG PG G P GP GP +PG G G Sbjct: 43 GAKGEKGEKGFPGPPGS---------PGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVR 93 Query: 576 GRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPP 634 G G PG G PG P G PG+TGP G G PG G KG++G PG+ G G PG G Sbjct: 94 GISGLPGFSGSPGLP---GTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAA 150 Query: 635 GPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSD 694 G G K I+++ G G L GP+G PGPPG PG G PG PG FG + Sbjct: 151 GLKGQKGAPAKEEDIELDAKGDPG-LPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM 209 Query: 695 VP-GPAGLPG--VPGREGPPGFPGLPGPPGPPGR-----EGPPGRT---GQKGSLGEAGA 743 P GP G G V G +G G GL GPPGPPG GP RT G+KG G G Sbjct: 210 GPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE 269 Query: 744 PGHKGSKGAPGPA-----GARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSG 798 PG G G PG + GA G+ GL G PG G PG PG G G GF + G Sbjct: 270 PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG---NRGFPGLMGED 326 Query: 799 GPFWSTARSADGPQGPPGLPG---------LKGDPGVPGLP---GAKGEVGADGVPGFPG 846 G + G GPPG G KGD G PG P GA+G G G PG PG Sbjct: 327 G-----IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPG 381 Query: 847 LPG--REGIAGPQGPKGDRGSRGEKGDPGKDGVGQ------------PGLPGPPGPPGPV 892 PG R G+ G G G +GS+GE+G PGKD +G PG PGPPGPPG + Sbjct: 382 SPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDI 441 Query: 893 VYVSEQDG----------------------------SVLSVPGPEGRPGFAGFPGPAGPK 924 V+ G +PGP G PG G G G Sbjct: 442 VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIP 501 Query: 925 GNLGSKGERGSPGPKGEKGEPGSIFSPDGGALG-PAQKGAKGEP-------GFRGPPGPY 976 G G+ G +GSPG G G PG F GA G P KG KGE G G PG Sbjct: 502 GRQGAAGLKGSPGSPGNTGLPG--FPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLR 559 Query: 977 GRPGYKGEIGFPGRPGRPGMNGLKGE---KGEPGDASLGFGMRGMPGPPGPPGPPGPPGT 1033 G+PG KG G PG PG G+ G KGE GE GD G G PG PG PGP GP G Sbjct: 560 GQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ----GPPGDPGSPGSPGPAGPAGP 615 Query: 1034 PVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEV-------GPPGPPGQFPFDFLQLEA 1086 P Y E G G+PG GPPG G +GE+ GPPGPPG Q Sbjct: 616 PGYGPQ--GEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPP 673 Query: 1087 EMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYP------GIPGPKGE-S 1139 + G G GD G G GEP G G PGPPGP G +G+P G PG GE Sbjct: 674 GIPGSLGKCGDPGLPGPDGEP---GIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPG 730 Query: 1140 IRGQPGPPGPQGPPGIGYEGRQGPPGPPGP------------PGPPSFPG-PHRQTISVP 1186 + G+PG PG +G P + G G PG PG PG P PG P + + Sbjct: 731 LPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNE--GLD 788 Query: 1187 GPPGPPGPPGPPGTMG 1202 GP G PG PGPPG G Sbjct: 789 GPRGDPGQPGPPGEQG 804 Score = 404 bits (1038), Expect = e-112 Identities = 289/717 (40%), Positives = 332/717 (46%), Gaps = 161/717 (22%) Query: 616 DKG----DPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPG 671 DKG D GE+G G GPPG PG GF GP G PG Sbjct: 35 DKGQCFCDGAKGEKGEKGFPGPPGSPGQK--------------GF-------TGPEGLPG 73 Query: 672 PPGPPGVPGLPGEPGRFGVNS-SDVPG---PAGLPGVPGREGPPGFPGLPGPPGPPGREG 727 P GP G PGLPG G GV S +PG GLPG PG GP G G+PG G G +G Sbjct: 74 PQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQG 133 Query: 728 PPGRTGQKGSLGEAGAPGHKGSKGAPGPA-----GARGESGLAGAPGPAGPPGPPGPPGP 782 PG G G G GA G KG KGAP A+G+ GL GAPGP G PGPPG PGP Sbjct: 134 FPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGP 193 Query: 783 PGPGLPAGFDDMEGSGGPFWSTARSAD---------------GPQGPPG----------- 816 GP P GF G+ GP + GP GPPG Sbjct: 194 VGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDN 253 Query: 817 ---LPGLKGDPGVPGLPGAKG-----------EVGADGVPGFPGLPGREGIAGPQGPKGD 862 L G KGD G G PG G E GA G PG G PG++G+ G G +G Sbjct: 254 RTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGV 313 Query: 863 RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSE-QDGSVLSVPGPEGRPGFAGFPGP 920 +G+RG G G+DG+ GQ G GPPG GP Y Q+ PGP G G G GP Sbjct: 314 KGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGP 373 Query: 921 AGPKGNLGSKGE-----RGSPGPKGEKGEPGSIFSPDGGALG----PAQKGAKGEPGFRG 971 +GP G GS G RG+PG G KG G P A+G P G+ G PG G Sbjct: 374 SGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPG 433 Query: 972 PPGPYG----RPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLG--------------- 1012 PPGP G R G G+ G PG G PG+ G+ G KGEPG Sbjct: 434 PPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493 Query: 1013 -FGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE---- 1067 G++G+PG G G G PG+P + PG PG PG QG PG KG KGE Sbjct: 494 LHGVKGIPGRQGAAGLKGSPGSP-------GNTGLPGFPGFPGAQGDPGLKGEKGETLQP 546 Query: 1068 ---VGPPGPPG------QFPFDFLQLEAEMKGEKGDRGD---AGQKGERGEPGGGGFFGS 1115 VG PG PG + D + +KG G +G+ +G+KG++G PG G GS Sbjct: 547 EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606 Query: 1116 SLPGPPGPPGPRGY--------------PGIPGPKGES-IRGQ-------PGPPGPQGPP 1153 PGP GP GP GY PG PGP GE+ RG+ PGPPGP GPP Sbjct: 607 --PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664 Query: 1154 GIGYEGRQGPPGPP---GPPGPPSFPGPHRQT----ISVPGPPGPPGPPGPPGTMGA 1203 G + G QGPPG P G G P PGP + I PGPPGP G G PGT G+ Sbjct: 665 G--HPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719 Score = 385 bits (990), Expect = e-106 Identities = 274/701 (39%), Positives = 309/701 (44%), Gaps = 147/701 (20%) Query: 452 PRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGG 511 P P PP PP G E R GAQ LPG + + G G Sbjct: 794 PGQPGPPGEQGPP---GRCIEGPR-------------GAQGLPGLNGLKGQQGRRGKTGP 837 Query: 512 RVKEG-------GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQT 564 + G G G+ G PG+PG G GP G PG PG+ P G G + Sbjct: 838 KGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIG--MMG 895 Query: 565 VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPK------GDKG 618 PG GPPGPPG GTPG+ G PG PG G+ G G +G G G+ GP GDKG Sbjct: 896 FPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKG 955 Query: 619 DPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP----- 672 +PG+ G G PG +G G PG G G L+ L GP G PGP Sbjct: 956 EPGLKGFAGNPGEKGNRGVPGMP--------------GLKG-LKGLPGPAGPPGPRGDLG 1000 Query: 673 ----PGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGL------------ 716 PG PG+ G+PG G G+ S G G G PGR G PG PG+ Sbjct: 1001 STGNPGEPGLRGIPGSMGNMGMPGSK--GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGY 1058 Query: 717 -----PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGP- 770 PGPPGP G G PG G+KG +G+ G PGH G G G G+ G GL G PGP Sbjct: 1059 SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPH 1118 Query: 771 -----------AGPPGPPGPPGPPG-PGLPA--------GFDDMEGSGGPFWSTA--RSA 808 GPPG GPPG PG PG P G D + G G T R+ Sbjct: 1119 GDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAP 1178 Query: 809 DGPQGPPGLPGLKGD---PGVPGLPGAKGEVG---------ADGVPGFPGLPGR--EGIA 854 GP+G PG G KGD PG PGLPG KG +G +G PG PGLPG G Sbjct: 1179 PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT 1238 Query: 855 GPQGPKGDRGSRGEKGDPGKDGV---------GQPGLPGPPGPPGPVVYVSEQDG----S 901 G +GP G RGS G G PG G G G PGP GPPG + Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPG 1298 Query: 902 VLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGAL----- 956 +PGP G PGF GFPG G KGN G G G PGP G KG PG D G L Sbjct: 1299 TPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG--VRGDPGTLKIISL 1356 Query: 957 --GPAQKGAKGEPGFRGPPGPYGRPGY---------KGEIGFPGRPGRPGMNGLKGEKGE 1005 P G GEPG +G PGP G PG G+ G PG PG G G KG KGE Sbjct: 1357 PGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGE 1416 Query: 1006 PGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR 1046 PG A G G+PG G G G P T VF S+ Sbjct: 1417 PGPA----GSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQ 1453 Score = 338 bits (868), Expect = 2e-92 Identities = 242/644 (37%), Positives = 286/644 (44%), Gaps = 119/644 (18%) Query: 421 GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 480 G D G G++GS + E G + P P + PP G + Sbjct: 845 GLDRSGFPGETGSPGIPGHQ---GEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIG 901 Query: 481 EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGG-----------LKGQKGEPGV-- 527 + G GS + G TPG + ++G + G KGEPG+ Sbjct: 902 PPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKG 961 Query: 528 ----PGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG----------PALQTVPGPQGPPG 573 PG G G PG P L G GLP P P GP G P L+ +PG G G Sbjct: 962 FAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMG 1021 Query: 574 PPGRDGT------PGRDGEPGDPGEDG--------------KPGDTGPQGFPGTPGDVGP 613 PG G PGR G PG PG G +PG GP G PG PGD+G Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGK 1081 Query: 614 KGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP 672 KG+ G PG G GP GP+G PG PG K G GDL +G +G GP Sbjct: 1082 KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK--------PGPHGDL-GFKGIKGLLGP 1132 Query: 673 PG---PPGVPGLPGEPGRFGVNSSD----VPGPAGLPGVPGR----EGPPGFPGLPGPPG 721 PG PPG+PG PG PG G+ +PGPAG G G GP G PG G G Sbjct: 1133 PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKG 1192 Query: 722 PPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARG-----ESGLAGAPGPAGPPGP 776 G G PG G+KG++G+AG G G +G PGP G G ++G G PG G PG Sbjct: 1193 DRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGA 1252 Query: 777 PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGL------PGLKGDPGVPGLP 830 PGPPGPPG + D G P GP+GPPG PG G PG PGLP Sbjct: 1253 PGPPGPPGSHVIGIKGDKGSMGHP---------GPKGPPGTAGDMGPPGRLGAPGTPGLP 1303 Query: 831 GAKGEVGADGVPGFPGL---PGREGIAGPQGPKGDRGSRGEKGDPGK-DGVGQPGLPGPP 886 G +G+ G G PG G PG G GP GP G +G G +GDPG + PG PGPP Sbjct: 1304 GPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPP 1363 Query: 887 GPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPG---PAGPKGNLGSKGERGSPGPKGEKG 943 G PG PG +G PG G PG P GP+G G G+ G+PGP GEKG Sbjct: 1364 GTPGE--------------PGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409 Query: 944 EPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGF 987 GS P GPA G+ G PG +G G G P GF Sbjct: 1410 NKGSKGEP-----GPA--GSDGLPGLKGKRGDSGSPATWTTRGF 1446 Score = 276 bits (706), Expect = 1e-73 Identities = 201/508 (39%), Positives = 230/508 (45%), Gaps = 106/508 (20%) Query: 747 KGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTAR 806 KG G G +GE G G PG G G GP G PGP P GF + G G Sbjct: 36 KGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTG------- 88 Query: 807 SADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPG---------FPGLP---GREGIA 854 + G +G GLPG G PG+PG PG G G GVPG FPGLP G GI Sbjct: 89 -SKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIP 147 Query: 855 GPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGF 914 G G KG +G+ ++ D D G PGLPG PGP+G PG Sbjct: 148 GAAGLKGQKGAPAKEEDIELDAKGDPGLPG--------------------APGPQGLPGP 187 Query: 915 AGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPG 974 GFPGP GP G G G G+ GP+G KG G +G KG +G G GPPG Sbjct: 188 PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGE------RVIG--HKGERGVKGLTGPPG 239 Query: 975 PYGR--------------PGYKGEIGFPGRPGRPGMNGLKGE-----KGEPGDASLGFGM 1015 P G G KG+ G G PG PG +GL GE KG PGD G+ Sbjct: 240 PPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDP----GL 295 Query: 1016 RGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPG 1075 +G PG G PG PG G G G PG G G KG KG++GPPG G Sbjct: 296 QGKPGKDGVPGFPGSEGVK-------------GNRGFPGLMGEDGIKGQKGDIGPPGFRG 342 Query: 1076 QFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGP--PGPRGYPGIP 1133 P ++ E KG++G G G +G RG G G G +PG PG PG RG PG P Sbjct: 343 --PTEYYDTYQE-KGDEGTPGPPGPRGARGPQGPSGPPG--VPGSPGSSRPGLRGAPGWP 397 Query: 1134 GPKG-ESIRGQPGPP--GPQGPPGI-GYEGRQGPPGPPGPPGPPSF----PGPHRQTISV 1185 G KG + RG+PG G G PG G G G PGPPGPPG F PG H Sbjct: 398 GLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH------ 451 Query: 1186 PGPPGPPGPPGPPGTMGASSGVRLWATR 1213 G PG G PG PG G L T+ Sbjct: 452 -GLPGYLGSPGIPGVDGPKGEPGLLCTQ 478 Score = 168 bits (426), Expect = 3e-41 Identities = 118/312 (37%), Positives = 134/312 (42%), Gaps = 72/312 (23%) Query: 946 GSIFSPDGGALGPAQKGAKGEPGFRGPP---------GPYGRPGYKGEIGFPGRPGRPGM 996 G + G KG KGE GF GPP GP G PG +G GFPG PG G Sbjct: 30 GCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGS 89 Query: 997 NGLKGEKGEPGDASLGFGMRGMPGPPGPPGP------------------PGPPGT----- 1033 G++G G PG + G G+PG PG GP PG PGT Sbjct: 90 KGVRGISGLPGFS----GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145 Query: 1034 -------------PVYDSNVFAES-SRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPF 1079 P + ++ ++ PG PG PG QG PGP G G VGPPGPPG F F Sbjct: 146 IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205 Query: 1080 DFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPP--------GPRGYPG 1131 KG G+R G KGERG G L GPPGPP GP Sbjct: 206 PGAMGPRGPKGHMGER-VIGHKGERGVKG--------LTGPPGPPGTVIVTLTGPDNRTD 256 Query: 1132 IPGPKGE-SIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPG 1190 + G KG+ G+PGPPGP G PG Y +G PG PG G P G PG G Sbjct: 257 LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDG----VPGFPGSEG 312 Query: 1191 PPGPPGPPGTMG 1202 G G PG MG Sbjct: 313 VKGNRGFPGLMG 324 Score = 34.7 bits (78), Expect = 0.72 Identities = 33/112 (29%), Positives = 41/112 (36%), Gaps = 11/112 (9%) Query: 150 GPLALAGPSSTPQENGTTLWPSRGIPSSPG--AHTTEAGTLPAPTPSPPSLGRPWAP-LT 206 GP AGP + L ++G+P +PG G L TP P G P P Sbjct: 608 GPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHP 667 Query: 207 GPSVPPPSSERISEEVGLLQLLGDPP-PQQVTQTDDPDVGLAYVFGPDANSG 257 GP PP G L GDP P + P +G GP + G Sbjct: 668 GPQGPPGIP-------GSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQG 712 >gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo sapiens] Length = 1670 Score = 512 bits (1318), Expect = e-144 Identities = 357/880 (40%), Positives = 410/880 (46%), Gaps = 160/880 (18%) Query: 426 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 485 G GD G LR + G +P P V P G E + S E +Q Sbjct: 551 GVPGDPG---------LRGQPGRKGLDGIPGTPGVKGLP---GPKGELALSGEKGDQGPP 598 Query: 486 ASLGAQTLPGSDSVSTWDGSVRTPG-GRVKEGGLKGQKGEPGVPGPPGRAGPPG----SP 540 G+ PG G PG G E GL+G +G PG PGPPG AGP G S Sbjct: 599 GDPGSPGSPGPA------GPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652 Query: 541 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGR------DGTPGRDGEPGDPGED- 593 +PGPPG P GP G PGPQGPPG PG G PG DGEPG PG Sbjct: 653 PVPGPPGPP------GPPGH-----PGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF 701 Query: 594 -GKPGDTGPQGFPGT---------------PGDVGPKGDKGDPGVGERGPPGPQGPPGPP 637 G PG G QGFPGT PG G G KG+P V G PG G PG Sbjct: 702 PGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGER 761 Query: 638 GPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPG 697 G S H ++ + G E L GPRG PG PGPPG G PG + +PG Sbjct: 762 GNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPG 821 Query: 698 PAGLPGVPGREG---PPGFPGLPG--PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA 752 GL G GR G P G PG+PG G PG G PG G +G +G G G+ G+ G Sbjct: 822 LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGI 881 Query: 753 PGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGLPAGFDDMEGSGGPFWSTARSA 808 GP G G G+ G PG GPPGPPG PG PG PG+P G G+ G A+ Sbjct: 882 LGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIP-GVKGQRGTPG-----AKGE 935 Query: 809 DGPQGPPG------LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGD 862 G +G PG + G KG+PG+ G G GE G GVPG PGL G +G+ GP GP G Sbjct: 936 QGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGP 995 Query: 863 RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGF---- 917 RG G G+PG+ G+ G PG G G PG S+ L PG GRPG G Sbjct: 996 RGDLGSTGNPGEPGLRGIPGSMGNMGMPG-----SKGKRGTLGFPGRAGRPGLPGIHGLQ 1050 Query: 918 -------------PGPAGPKGN------LGSKGERGSPGPKGE------KGEPGSIFSPD 952 PGP GP G+ +G KGE G PGP G +G PGS SP Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110 Query: 953 -GGALGP-------AQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG 1004 G GP KG G PG RGPPG G PG G +G G GR G+ G GEKG Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170 Query: 1005 EPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR-----------PGPPGLP 1053 E G G RG PG G G G PG P A PGPPGLP Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230 Query: 1054 G--------NQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERG 1105 G N+GPPG +G+ G GPPGPPG + + G KGD+G G G +G Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPG----------SHVIGIKGDKGSMGHPGPKG 1280 Query: 1106 EPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE-SIRGQPGPPGPQGPPGIGYEGRQGPP 1164 PG G G PPG G G PG+PGP+G+ +G PG G +G PG + G GPP Sbjct: 1281 PPGTAGDMG-----PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG--FLGSIGPP 1333 Query: 1165 GPPGPPGPPSFPGPHR--QTISVPGPPGPPGPPGPPGTMG 1202 GP GP GPP G + IS+PG PGPPG PG PG G Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373 Score = 480 bits (1235), Expect = e-135 Identities = 351/939 (37%), Positives = 415/939 (44%), Gaps = 186/939 (19%) Query: 423 DSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQ 482 D+ GD G+ R G + P +P P + P L G + + E Sbjct: 348 DTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERG 407 Query: 483 TTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCL 542 A PGS + G +PG G + +KG PG G PG G PG P + Sbjct: 408 RP--GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGV 465 Query: 543 PGP---PGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT 599 GP PGL C P P P L +PG G G PGR G G G PG PG G PG Sbjct: 466 DGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGF- 524 Query: 600 GPQGFPGTPGDVGPKGDK-------------GDPGV-GERGPPGPQGPPGPPGPSFRHDK 645 GFPG GD G KG+K GDPG+ G+ G G G PG PG Sbjct: 525 --PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG------- 575 Query: 646 LTFIDMEG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRF---GVNSSDVPGPAGL 701 ++G G G+L AL G +G GPPG PG PG PG G G PG G Sbjct: 576 -----VKGLPGPKGEL-ALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGT 629 Query: 702 PGVPGREGPPG-------------FPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKG 748 GVPG GPPG PG PGPPGPPG GP G G GSLG+ G PG G Sbjct: 630 QGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPG 689 Query: 749 SKGA--------PGPAGARGESGLAGAPGPAGPPGPPGPPGPPG-PGLPAGFDDME---- 795 G PGP G +G+ G G G G PG G PG PG PGLP + Sbjct: 690 PDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMP 749 Query: 796 -GSGGPFWSTARSADGPQGP---PGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGR- 850 G G P + R G G PGLPGL G PG GL G +G+ G G PG G PGR Sbjct: 750 GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809 Query: 851 ----------EGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQ-- 898 G+ G +G +G RG G KGDPG G+ + G PG G PG + E Sbjct: 810 IEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGP 869 Query: 899 --------DGSVLSVPGPEGRPGFAGFP---GPAGPKGNLGS------------KGERGS 935 + +L PG +G G GFP GP GP GN G+ KG+RG+ Sbjct: 870 LGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929 Query: 936 PGPKGEKGEPGSIFSPD--------------GGALGPAQKGAKGEP------GFRGPPGP 975 PG KGE+G+ G+ + G A P +KG +G P G +G PGP Sbjct: 930 PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989 Query: 976 YGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPG-------DASLGF-GMRGMPGPPGPPGP 1027 G PG +G++G G PG PG+ G+ G G G +LGF G G PG PG G Sbjct: 990 AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049 Query: 1028 PGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQF------PFDF 1081 G G P Y +E +RPGPPG G+ G PG G KGE+G PGPPG Sbjct: 1050 QGDKGEPGY-----SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPG 1104 Query: 1082 LQLEAEMKGEKGDRGDAGQK---------GERGEPGGGGFFGS-------------SLPG 1119 + G+ G GD G K G RG PG GF GS +PG Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG 1164 Query: 1120 PPG----------PPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-IGYEGRQGPPGPPG 1168 P G PPGPRG PG G KG+ RG PG PG G G +G G +GP G G Sbjct: 1165 PAGEKGETGLLRAPPGPRGNPGAQGAKGD--RGAPGFPGLPGRKGAMGDAGPRGPTGIEG 1222 Query: 1169 PPGPPSFPGP-------HRQTISVPGPPGPPGPPGPPGT 1200 PGPP PG +R G PG PGPPGPPG+ Sbjct: 1223 FPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGS 1261 Score = 470 bits (1209), Expect = e-132 Identities = 340/890 (38%), Positives = 403/890 (45%), Gaps = 195/890 (21%) Query: 489 GAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSPCLPGP- 545 G + LPG + G G + G GL G G PG+PG PG GP G +PG Sbjct: 67 GPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCS 126 Query: 546 --------PGLPCPVSPLG-PAGPALQTVPGPQGPP-----------GPPGRDGTPGRDG 585 PGLP LG P P + G +G P G PG G PG G Sbjct: 127 GSKGEQGFPGLP---GTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQG 183 Query: 586 EPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPG---VGERGPPGPQGPPGPPGPSFR 642 PG PG G G GP GF G PG +GP+G KG G +G +G G +G GPPGP Sbjct: 184 LPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGP--- 240 Query: 643 HDKLTFIDMEGSGFGGDLEALRGPRGF---PGPPGP--------------PGVPGLPGEP 685 + + G DL+ +G +G PGPPGP PG PGL G+P Sbjct: 241 -PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKP 299 Query: 686 GRFGV----NSSDVPGPAGLPGVPGRE---------GPPGF---------------PGLP 717 G+ GV S V G G PG+ G + GPPGF G P Sbjct: 300 GKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTP 359 Query: 718 GPPGP-----------------------PGREGPPGRTGQKGSLGEAGAPGHKGSKGAPG 754 GPPGP PG G PG G KGS GE G PG K + G PG Sbjct: 360 GPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGTPG 418 Query: 755 PAGARGESGLAGAPGPAGPP-------GPPGPPGPPG----PGLPAGFDDMEGSGGPFWS 803 G G GL G+PGP GPP GPPG G PG PG+P G D +G G + Sbjct: 419 SPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIP-GVDGPKGEPGLLCT 477 Query: 804 TARSADGPQGPPGLPGLKGDPGVP------GLPGAKGEVGADGVPGFPGLPGREGIAGPQ 857 GP G PGLPGL G G+P GL G+ G G G+PGFPG PG +G G + Sbjct: 478 QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK 537 Query: 858 GPK-------------GDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVL 903 G K GD G RG+ G G DG+ G PG+ G PGP G + E+ Sbjct: 538 GEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ-- 595 Query: 904 SVPGPEGRPGFAGFPGPAGPKGN-----------LGSKGERGSPGPKGEKGEPG--SIFS 950 GP G PG G PGPAGP G G++G G+PGP GE G G S+ + Sbjct: 596 ---GPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652 Query: 951 PDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGL--------KGE 1002 P G GP G G PG +GPPG G G G+ G PG G PG+ G+ KG+ Sbjct: 653 PVPGPPGP--PGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGD 710 Query: 1003 KGEPG-DASLG----FGMRGMPGPPGPPGP--------PGPPGTPVY-----DSNVFAES 1044 +G PG SLG G G+PG PG PG PG PGTP + +S E Sbjct: 711 QGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEI 770 Query: 1045 SRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAE--------MKGEKGDRG 1096 PG PGLPG G G G +G+ G PGPPG+ +E + G KG +G Sbjct: 771 GLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQG 830 Query: 1097 DAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-- 1154 G+ G +G+PG G S PG G PG G+ G GP G+ RG PG PG GPPG Sbjct: 831 RRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ--RGYPGNPGILGPPGED 888 Query: 1155 --IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1202 IG G G GPPGPPG P PG R + +PG G G PG G G Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGTPG-QRGSPGIPGVKGQRGTPGAKGEQG 937 Score = 454 bits (1168), Expect = e-127 Identities = 322/796 (40%), Positives = 364/796 (45%), Gaps = 144/796 (18%) Query: 517 GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP-ALQTVPGPQGPPGPP 575 G KG+KGE G PGPPG PG G P GP GP +PG G G Sbjct: 43 GAKGEKGEKGFPGPPGS---------PGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVR 93 Query: 576 GRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPP 634 G G PG G PG P G PG+TGP G G PG G KG++G PG+ G G PG G Sbjct: 94 GISGLPGFSGSPGLP---GTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAA 150 Query: 635 GPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSD 694 G G K I+++ G G L GP+G PGPPG PG G PG PG FG + Sbjct: 151 GLKGQKGAPAKEEDIELDAKGDPG-LPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM 209 Query: 695 VP-GPAGLPG--VPGREGPPGFPGLPGPPGPPGR-----EGPPGRT---GQKGSLGEAGA 743 P GP G G V G +G G GL GPPGPPG GP RT G+KG G G Sbjct: 210 GPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE 269 Query: 744 PGHKGSKGAPGPA-----GARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSG 798 PG G G PG + GA G+ GL G PG G PG PG G G GF + G Sbjct: 270 PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG---NRGFPGLMGED 326 Query: 799 GPFWSTARSADGPQGPPGLPG---------LKGDPGVPGLP---GAKGEVGADGVPGFPG 846 G + G GPPG G KGD G PG P GA+G G G PG PG Sbjct: 327 G-----IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPG 381 Query: 847 LPG--REGIAGPQGPKGDRGSRGEKGDPGKDGVGQ------------PGLPGPPGPPGPV 892 PG R G+ G G G +GS+GE+G PGKD +G PG PGPPGPPG + Sbjct: 382 SPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDI 441 Query: 893 VYVSEQDG----------------------------SVLSVPGPEGRPGFAGFPGPAGPK 924 V+ G +PGP G PG G G G Sbjct: 442 VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIP 501 Query: 925 GNLGSKGERGSPGPKGEKGEPGSIFSPDGGALG-PAQKGAKGEP-------GFRGPPGPY 976 G G+ G +GSPG G G PG F GA G P KG KGE G G PG Sbjct: 502 GRQGAAGLKGSPGSPGNTGLPG--FPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLR 559 Query: 977 GRPGYKGEIGFPGRPGRPGMNGLKGE---KGEPGDASLGFGMRGMPGPPGPPGPPGPPGT 1033 G+PG KG G PG PG G+ G KGE GE GD G G PG PG PGP GP G Sbjct: 560 GQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ----GPPGDPGSPGSPGPAGPAGP 615 Query: 1034 PVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEV-------GPPGPPGQFPFDFLQLEA 1086 P Y E G G+PG GPPG G +GE+ GPPGPPG Q Sbjct: 616 PGYGPQ--GEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPP 673 Query: 1087 EMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYP------GIPGPKGE-S 1139 + G G GD G G GEP G G PGPPGP G +G+P G PG GE Sbjct: 674 GIPGSLGKCGDPGLPGPDGEP---GIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPG 730 Query: 1140 IRGQPGPPGPQGPPGIGYEGRQGPPGPPGP------------PGPPSFPG-PHRQTISVP 1186 + G+PG PG +G P + G G PG PG PG P PG P + + Sbjct: 731 LPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNE--GLD 788 Query: 1187 GPPGPPGPPGPPGTMG 1202 GP G PG PGPPG G Sbjct: 789 GPRGDPGQPGPPGEQG 804 Score = 404 bits (1038), Expect = e-112 Identities = 289/717 (40%), Positives = 332/717 (46%), Gaps = 161/717 (22%) Query: 616 DKG----DPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPG 671 DKG D GE+G G GPPG PG GF GP G PG Sbjct: 35 DKGQCFCDGAKGEKGEKGFPGPPGSPGQK--------------GF-------TGPEGLPG 73 Query: 672 PPGPPGVPGLPGEPGRFGVNS-SDVPG---PAGLPGVPGREGPPGFPGLPGPPGPPGREG 727 P GP G PGLPG G GV S +PG GLPG PG GP G G+PG G G +G Sbjct: 74 PQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQG 133 Query: 728 PPGRTGQKGSLGEAGAPGHKGSKGAPGPA-----GARGESGLAGAPGPAGPPGPPGPPGP 782 PG G G G GA G KG KGAP A+G+ GL GAPGP G PGPPG PGP Sbjct: 134 FPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGP 193 Query: 783 PGPGLPAGFDDMEGSGGPFWSTARSAD---------------GPQGPPG----------- 816 GP P GF G+ GP + GP GPPG Sbjct: 194 VGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDN 253 Query: 817 ---LPGLKGDPGVPGLPGAKG-----------EVGADGVPGFPGLPGREGIAGPQGPKGD 862 L G KGD G G PG G E GA G PG G PG++G+ G G +G Sbjct: 254 RTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGV 313 Query: 863 RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSE-QDGSVLSVPGPEGRPGFAGFPGP 920 +G+RG G G+DG+ GQ G GPPG GP Y Q+ PGP G G G GP Sbjct: 314 KGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGP 373 Query: 921 AGPKGNLGSKGE-----RGSPGPKGEKGEPGSIFSPDGGALG----PAQKGAKGEPGFRG 971 +GP G GS G RG+PG G KG G P A+G P G+ G PG G Sbjct: 374 SGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPG 433 Query: 972 PPGPYG----RPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLG--------------- 1012 PPGP G R G G+ G PG G PG+ G+ G KGEPG Sbjct: 434 PPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493 Query: 1013 -FGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE---- 1067 G++G+PG G G G PG+P + PG PG PG QG PG KG KGE Sbjct: 494 LHGVKGIPGRQGAAGLKGSPGSP-------GNTGLPGFPGFPGAQGDPGLKGEKGETLQP 546 Query: 1068 ---VGPPGPPG------QFPFDFLQLEAEMKGEKGDRGD---AGQKGERGEPGGGGFFGS 1115 VG PG PG + D + +KG G +G+ +G+KG++G PG G GS Sbjct: 547 EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606 Query: 1116 SLPGPPGPPGPRGY--------------PGIPGPKGES-IRGQ-------PGPPGPQGPP 1153 PGP GP GP GY PG PGP GE+ RG+ PGPPGP GPP Sbjct: 607 --PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664 Query: 1154 GIGYEGRQGPPGPP---GPPGPPSFPGPHRQT----ISVPGPPGPPGPPGPPGTMGA 1203 G + G QGPPG P G G P PGP + I PGPPGP G G PGT G+ Sbjct: 665 G--HPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719 Score = 385 bits (990), Expect = e-106 Identities = 274/701 (39%), Positives = 309/701 (44%), Gaps = 147/701 (20%) Query: 452 PRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGG 511 P P PP PP G E R GAQ LPG + + G G Sbjct: 794 PGQPGPPGEQGPP---GRCIEGPR-------------GAQGLPGLNGLKGQQGRRGKTGP 837 Query: 512 RVKEG-------GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQT 564 + G G G+ G PG+PG G GP G PG PG+ P G G + Sbjct: 838 KGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIG--MMG 895 Query: 565 VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPK------GDKG 618 PG GPPGPPG GTPG+ G PG PG G+ G G +G G G+ GP GDKG Sbjct: 896 FPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKG 955 Query: 619 DPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP----- 672 +PG+ G G PG +G G PG G G L+ L GP G PGP Sbjct: 956 EPGLKGFAGNPGEKGNRGVPGMP--------------GLKG-LKGLPGPAGPPGPRGDLG 1000 Query: 673 ----PGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGL------------ 716 PG PG+ G+PG G G+ S G G G PGR G PG PG+ Sbjct: 1001 STGNPGEPGLRGIPGSMGNMGMPGSK--GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGY 1058 Query: 717 -----PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGP- 770 PGPPGP G G PG G+KG +G+ G PGH G G G G+ G GL G PGP Sbjct: 1059 SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPH 1118 Query: 771 -----------AGPPGPPGPPGPPG-PGLPA--------GFDDMEGSGGPFWSTA--RSA 808 GPPG GPPG PG PG P G D + G G T R+ Sbjct: 1119 GDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAP 1178 Query: 809 DGPQGPPGLPGLKGD---PGVPGLPGAKGEVG---------ADGVPGFPGLPGR--EGIA 854 GP+G PG G KGD PG PGLPG KG +G +G PG PGLPG G Sbjct: 1179 PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT 1238 Query: 855 GPQGPKGDRGSRGEKGDPGKDGV---------GQPGLPGPPGPPGPVVYVSEQDG----S 901 G +GP G RGS G G PG G G G PGP GPPG + Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPG 1298 Query: 902 VLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGAL----- 956 +PGP G PGF GFPG G KGN G G G PGP G KG PG D G L Sbjct: 1299 TPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG--VRGDPGTLKIISL 1356 Query: 957 --GPAQKGAKGEPGFRGPPGPYGRPGY---------KGEIGFPGRPGRPGMNGLKGEKGE 1005 P G GEPG +G PGP G PG G+ G PG PG G G KG KGE Sbjct: 1357 PGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGE 1416 Query: 1006 PGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR 1046 PG A G G+PG G G G P T VF S+ Sbjct: 1417 PGPA----GSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQ 1453 Score = 338 bits (868), Expect = 2e-92 Identities = 242/644 (37%), Positives = 286/644 (44%), Gaps = 119/644 (18%) Query: 421 GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 480 G D G G++GS + E G + P P + PP G + Sbjct: 845 GLDRSGFPGETGSPGIPGHQ---GEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIG 901 Query: 481 EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGG-----------LKGQKGEPGV-- 527 + G GS + G TPG + ++G + G KGEPG+ Sbjct: 902 PPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKG 961 Query: 528 ----PGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG----------PALQTVPGPQGPPG 573 PG G G PG P L G GLP P P GP G P L+ +PG G G Sbjct: 962 FAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMG 1021 Query: 574 PPGRDGT------PGRDGEPGDPGEDG--------------KPGDTGPQGFPGTPGDVGP 613 PG G PGR G PG PG G +PG GP G PG PGD+G Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGK 1081 Query: 614 KGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP 672 KG+ G PG G GP GP+G PG PG K G GDL +G +G GP Sbjct: 1082 KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK--------PGPHGDL-GFKGIKGLLGP 1132 Query: 673 PG---PPGVPGLPGEPGRFGVNSSD----VPGPAGLPGVPGR----EGPPGFPGLPGPPG 721 PG PPG+PG PG PG G+ +PGPAG G G GP G PG G G Sbjct: 1133 PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKG 1192 Query: 722 PPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARG-----ESGLAGAPGPAGPPGP 776 G G PG G+KG++G+AG G G +G PGP G G ++G G PG G PG Sbjct: 1193 DRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGA 1252 Query: 777 PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGL------PGLKGDPGVPGLP 830 PGPPGPPG + D G P GP+GPPG PG G PG PGLP Sbjct: 1253 PGPPGPPGSHVIGIKGDKGSMGHP---------GPKGPPGTAGDMGPPGRLGAPGTPGLP 1303 Query: 831 GAKGEVGADGVPGFPGL---PGREGIAGPQGPKGDRGSRGEKGDPGK-DGVGQPGLPGPP 886 G +G+ G G PG G PG G GP GP G +G G +GDPG + PG PGPP Sbjct: 1304 GPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPP 1363 Query: 887 GPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPG---PAGPKGNLGSKGERGSPGPKGEKG 943 G PG PG +G PG G PG P GP+G G G+ G+PGP GEKG Sbjct: 1364 GTPGE--------------PGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409 Query: 944 EPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGF 987 GS P GPA G+ G PG +G G G P GF Sbjct: 1410 NKGSKGEP-----GPA--GSDGLPGLKGKRGDSGSPATWTTRGF 1446 Score = 276 bits (706), Expect = 1e-73 Identities = 201/508 (39%), Positives = 230/508 (45%), Gaps = 106/508 (20%) Query: 747 KGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTAR 806 KG G G +GE G G PG G G GP G PGP P GF + G G Sbjct: 36 KGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTG------- 88 Query: 807 SADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPG---------FPGLP---GREGIA 854 + G +G GLPG G PG+PG PG G G GVPG FPGLP G GI Sbjct: 89 -SKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIP 147 Query: 855 GPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGF 914 G G KG +G+ ++ D D G PGLPG PGP+G PG Sbjct: 148 GAAGLKGQKGAPAKEEDIELDAKGDPGLPG--------------------APGPQGLPGP 187 Query: 915 AGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPG 974 GFPGP GP G G G G+ GP+G KG G +G KG +G G GPPG Sbjct: 188 PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGE------RVIG--HKGERGVKGLTGPPG 239 Query: 975 PYGR--------------PGYKGEIGFPGRPGRPGMNGLKGE-----KGEPGDASLGFGM 1015 P G G KG+ G G PG PG +GL GE KG PGD G+ Sbjct: 240 PPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDP----GL 295 Query: 1016 RGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPG 1075 +G PG G PG PG G G G PG G G KG KG++GPPG G Sbjct: 296 QGKPGKDGVPGFPGSEGVK-------------GNRGFPGLMGEDGIKGQKGDIGPPGFRG 342 Query: 1076 QFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGP--PGPRGYPGIP 1133 P ++ E KG++G G G +G RG G G G +PG PG PG RG PG P Sbjct: 343 --PTEYYDTYQE-KGDEGTPGPPGPRGARGPQGPSGPPG--VPGSPGSSRPGLRGAPGWP 397 Query: 1134 GPKG-ESIRGQPGPP--GPQGPPGI-GYEGRQGPPGPPGPPGPPSF----PGPHRQTISV 1185 G KG + RG+PG G G PG G G G PGPPGPPG F PG H Sbjct: 398 GLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH------ 451 Query: 1186 PGPPGPPGPPGPPGTMGASSGVRLWATR 1213 G PG G PG PG G L T+ Sbjct: 452 -GLPGYLGSPGIPGVDGPKGEPGLLCTQ 478 Score = 168 bits (426), Expect = 3e-41 Identities = 118/312 (37%), Positives = 134/312 (42%), Gaps = 72/312 (23%) Query: 946 GSIFSPDGGALGPAQKGAKGEPGFRGPP---------GPYGRPGYKGEIGFPGRPGRPGM 996 G + G KG KGE GF GPP GP G PG +G GFPG PG G Sbjct: 30 GCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGS 89 Query: 997 NGLKGEKGEPGDASLGFGMRGMPGPPGPPGP------------------PGPPGT----- 1033 G++G G PG + G G+PG PG GP PG PGT Sbjct: 90 KGVRGISGLPGFS----GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145 Query: 1034 -------------PVYDSNVFAES-SRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPF 1079 P + ++ ++ PG PG PG QG PGP G G VGPPGPPG F F Sbjct: 146 IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205 Query: 1080 DFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPP--------GPRGYPG 1131 KG G+R G KGERG G L GPPGPP GP Sbjct: 206 PGAMGPRGPKGHMGER-VIGHKGERGVKG--------LTGPPGPPGTVIVTLTGPDNRTD 256 Query: 1132 IPGPKGE-SIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPG 1190 + G KG+ G+PGPPGP G PG Y +G PG PG G P G PG G Sbjct: 257 LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDG----VPGFPGSEG 312 Query: 1191 PPGPPGPPGTMG 1202 G G PG MG Sbjct: 313 VKGNRGFPGLMG 324 Score = 34.7 bits (78), Expect = 0.72 Identities = 33/112 (29%), Positives = 41/112 (36%), Gaps = 11/112 (9%) Query: 150 GPLALAGPSSTPQENGTTLWPSRGIPSSPG--AHTTEAGTLPAPTPSPPSLGRPWAP-LT 206 GP AGP + L ++G+P +PG G L TP P G P P Sbjct: 608 GPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHP 667 Query: 207 GPSVPPPSSERISEEVGLLQLLGDPP-PQQVTQTDDPDVGLAYVFGPDANSG 257 GP PP G L GDP P + P +G GP + G Sbjct: 668 GPQGPPGIP-------GSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQG 712 >gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] Length = 1073 Score = 504 bits (1297), Expect = e-142 Identities = 337/832 (40%), Positives = 383/832 (46%), Gaps = 134/832 (16%) Query: 468 GSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGV 527 G ED + + + G PG + G+ PG R ++G +G+KGE G+ Sbjct: 253 GERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGD-QGEKGELGL 311 Query: 528 PG------PPGRAGPPGSPCLPGP-------PGLPCPVSPLG-------PAGPALQTVPG 567 PG G AGP G P LPG P +P P G P P LQ PG Sbjct: 312 PGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPG 371 Query: 568 ---PQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-- 622 PQGP GPPG G G G PG G G PG G G G PG VG G +G PG Sbjct: 372 ELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDG 431 Query: 623 --GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP------PG 674 GE+G G +G PGP GP G G G+ LRG G PGP G Sbjct: 432 ERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGE-PGLRGSPGLPGPLGTKGDRG 490 Query: 675 PPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREG-----PP 729 PG+PG PG G G+ + PGP+G PG G G G PG PGP GP GR+G P Sbjct: 491 APGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSP 550 Query: 730 GRTG----------QKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGP 779 G G G G PG KG KG PG G G G G GP G PGPPG Sbjct: 551 GDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGI 610 Query: 780 PGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGAD 839 GP G G D G G QG PG+PG G PG PG PGA G GA Sbjct: 611 AGPQGSQGERGADGEVGQ-----------KGDQGHPGVPGFMGPPGNPGPPGADGIAGAA 659 Query: 840 GVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG----------VGQPGLPGPPGPP 889 G PG G PG+EG GPQGP G G GE+G G+DG G+PGLPGP G Sbjct: 660 GPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGAR 719 Query: 890 GPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIF 949 GP + S PGP G G G PG G G G G G GP+G +G PG Sbjct: 720 GPPGFKGHTGDS--GAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNG 777 Query: 950 SPD-----GGALGPAQKGAKGE------PGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNG 998 SP G + P QKG+KGE PGF GP GP G PG KG G G PG+PG G Sbjct: 778 SPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPG 837 Query: 999 LKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGP 1058 KGE+G+PG ++G GPPG G PG PG P + + + GP GLPG GP Sbjct: 838 FKGERGDPG-------IKGDKGPPGGKGQPGDPGIPGHKGH----TGLMGPQGLPGENGP 886 Query: 1059 PGPKGAKGEVGPPGPPGQFP-FDFL----------QLE------------AEMKGEKGDR 1095 GP G G+ G PG G+ P + L QLE A MK +G Sbjct: 887 VGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRP 946 Query: 1096 GDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI 1155 G G G+ G PG G G PG PG G G G GPKGE RG G PG PG+ Sbjct: 947 GPPGPPGKDGLPGRAGPMGE--PGRPGQGGLEGPSGPIGPKGE--RGAKGDPGA---PGV 999 Query: 1156 GYEGRQGPPGPPGPPGPPSF--------PGPHRQTISVPGPPGPPGPPGPPG 1199 G G GPPG PG PG P + PGP +T G PG PGPPGPPG Sbjct: 1000 GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGET-GPAGHPGLPGPPGPPG 1050 Score = 497 bits (1280), Expect = e-140 Identities = 326/790 (41%), Positives = 378/790 (47%), Gaps = 122/790 (15%) Query: 505 SVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG-PALQ 563 + +T G + G G++GE G+PG PG G G L G PG G AG P Sbjct: 238 AAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPG------EKGEAGLPGAP 291 Query: 564 TVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGT----------PGDVGP 613 PG +G G G G G G GD GE G+ G GP G PGT PG+ GP Sbjct: 292 GFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGP 351 Query: 614 KGDKGDPGV----------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEAL 663 KG+KGDPG+ GE GP GP GPPG G H G G+ A Sbjct: 352 KGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHG--------APGAAGNPGA- 402 Query: 664 RGPRGFPGPPGPPG---VPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP 720 G G PGP GPPG PGL G PG+ G G AG G PG GP G PG PG P Sbjct: 403 PGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEK--GAAGEEGSPGPVGPRGDPGAPGLP 460 Query: 721 GPPGR--EGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGL--AGAPGPAGPPGP 776 GPPG+ +G PG G G G G G +G+ G PG G+RG+ G+ AG PGP+GPPG Sbjct: 461 GPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGD 520 Query: 777 PGPPGP------PGPGLPAGFDDMEGSGGPFWSTARSAD-------GPQGPPGLPGLKGD 823 G PG PGP PAG D + P + D GP G PGLPG KGD Sbjct: 521 KGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGD 580 Query: 824 PGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGL 882 GVPG PG +G G G G PGLPG GIAGPQG +G+RG+ GE G G G G PG Sbjct: 581 KGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGF 640 Query: 883 PGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEK 942 GPPG PGP ++ PG +G PG G PGP GP G G GE G G G+ Sbjct: 641 MGPPGNPGPPG--ADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKP 698 Query: 943 GEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGE 1002 G PG L P +GA+G PGF+G G G PG +GE G G PG+ G+ G G+ Sbjct: 699 GPPGEPGKAGEPGL-PGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGD 757 Query: 1003 KGEPGDASLGFGMRGMPGP---PGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPP 1059 G G G RG PG PG PG PGP GTP + E+ PG PG G +GPP Sbjct: 758 TGPTGPQGPQ-GPRGPPGKNGSPGSPGEPGPSGTPGQKGSK-GENGSPGLPGFLGPRGPP 815 Query: 1060 GP---KGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSS 1116 G KG G+ G PG PG+ F + + +KG+KG G GQ G+ G PG G G Sbjct: 816 GEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLM 875 Query: 1117 LP-------GPPGPPGPRGYPGIPGPKGES------------------------------ 1139 P GP GPPGP G PG PG +GES Sbjct: 876 GPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMP 935 Query: 1140 ------IRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPG 1193 +G+PGPPGP G G+ GR GP G PG PG GP GP GP G Sbjct: 936 PAYMKSSQGRPGPPGPPGKDGL--PGRAGPMGEPGRPGQGGLEGPS-------GPIGPKG 986 Query: 1194 PPGPPGTMGA 1203 G G GA Sbjct: 987 ERGAKGDPGA 996 Score = 471 bits (1211), Expect = e-132 Identities = 323/799 (40%), Positives = 363/799 (45%), Gaps = 154/799 (19%) Query: 426 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 485 G GD G L E G +P P T PP A G Sbjct: 353 GEKGDPG---------LPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPG------AA 397 Query: 486 ASLGAQTLPGSDSVSTWDGSVRTPG-----GRVKEGGLKGQKGEPGVPGPPGRAGPPGSP 540 + GA G+ S GSV PG G+ E G KG GE G PGP G G PG+P Sbjct: 398 GNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAP 457 Query: 541 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG 600 LPGPPG G G PG +G PG PG GT G G PG PG G GD G Sbjct: 458 GLPGPPGK-------GKDGE-----PGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPG 505 Query: 601 PQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDL 660 G G PG GP GDKG P G RG PG GP GP G L+ GD+ Sbjct: 506 -IGVAGPPGPSGPPGDKGSP--GSRGLPGFPGPQGPAGRDGLSSLLS---------PGDI 553 Query: 661 EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLP--- 717 L PPGPPG+PGLPG G GV PG G G G GPPG PG P Sbjct: 554 NLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGK--PGREGTEGKKGEAGPPGLPGPPGIA 611 Query: 718 GPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPP 777 GP G G G G GQKG G G PG G G PGP GA G +G AG PG G PG Sbjct: 612 GPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKE 671 Query: 778 GPPGPPGP-GLPA-----GFDDMEGSGGPFWSTARSAD----GPQGPPGLPGLKGDPGVP 827 GPPGP GP GLP G + +G GP ++ + GP+G G PG KG G Sbjct: 672 GPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDS 731 Query: 828 GLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPP 886 G PG +GE GA G+PG GLPG++G GP GP+G +G R G PGK+G G PG PGP Sbjct: 732 GAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPR---GPPGKNGSPGSPGEPGPS 788 Query: 887 GPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPG 946 G PG Q GS G G PG GF GP GP G G KG G G G+ GEPG Sbjct: 789 GTPG-------QKGS----KGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPG 837 Query: 947 SIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEP 1006 KG +G+PG +G GP PG KG+ G PG PG G GL G +G P Sbjct: 838 F-------------KGERGDPGIKGDKGP---PGGKGQPGDPGIPGHKGHTGLMGPQGLP 881 Query: 1007 GDASLGFGMRGMPGPPGPPGPPGPPG---------------------------------- 1032 G+ G GPPGPPG PG PG Sbjct: 882 GE-------NGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQM 934 Query: 1033 TPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEK 1092 P Y + + RPGPPG PG G PG G GE G PG G ++G Sbjct: 935 PPAY---MKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGG------------LEGPS 979 Query: 1093 GDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGP 1152 G G G++G +G+PG G L G GPPG G PG PG + + G PGP G GP Sbjct: 980 GPIGPKGERGAKGDPGAPGV---GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGP 1036 Query: 1153 PGIGYEGRQGPPGPPGPPG 1171 G G PGPPGPPG Sbjct: 1037 -----AGHPGLPGPPGPPG 1050 Score = 447 bits (1151), Expect = e-125 Identities = 302/771 (39%), Positives = 356/771 (46%), Gaps = 154/771 (19%) Query: 529 GPPGRAGPPGSPCLPGPPGLPCPV---------SPLGPAGPALQ-------------TVP 566 G G G + LP C + + LG GPA Q T P Sbjct: 184 GAQGACGRGNTSVLPSSVAPQCSMPKGTGHEFSAALGTQGPADQRADARASCILAAKTAP 243 Query: 567 GPQ---GPPGPPGRDGTPGRDGEPGDPGEDG---KPGDTGPQGFPGTPGDVGPKGDKGDP 620 G + G PG G DG PG+ G G+ GE G +PG+ G G PG PG G +G+KGD Sbjct: 244 GLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQ 303 Query: 621 GV-------------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPR 667 G GE+G GP GPPG PG T + G+ +GP+ Sbjct: 304 GEKGELGLPGLKGDRGEKGEAGPAGPPGLPGT-------TSLFTPHPRMPGE----QGPK 352 Query: 668 GFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREG 727 G G PG PG PGL G PG G GP G PG G+EG G PG G PG PG G Sbjct: 353 GEKGDPGLPGEPGLQGRPGELGPQ-----GPTGPPGAKGQEGAHGAPGAAGNPGAPGHVG 407 Query: 728 PPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGL 787 PG +G GS+G APG +G+ G G G +G +G G+PGP GP G PG PG PGP Sbjct: 408 APGPSGPPGSVG---APGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPP- 463 Query: 788 PAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGL 847 +G G PGL+G PG+PG G KG+ GA G+PG PG Sbjct: 464 -----------------------GKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGS 500 Query: 848 PGREGIA-----GPQGPKGDRGSRGEKGDPGKDG----VGQPGL-----PG--------- 884 G GI GP GP GD+GS G +G PG G G+ GL PG Sbjct: 501 RGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDV 560 Query: 885 ----PPGPPG-PVVYVSEQDGSVLSVPGPEGR---------PGFAGFPGPAGPKGNLGSK 930 PPGPPG P + + D V PG EG PG G PG AGP+G+ G + Sbjct: 561 CNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGER 620 Query: 931 GERGSPGPKGEKGEPG--SIFSPDGGALGPAQ---KGAKGEPGFRGPPGPYGRPGYKGEI 985 G G G KG++G PG P G P GA G PG +G PG G PG +G Sbjct: 621 GADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPS 680 Query: 986 GFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESS 1045 G PG PG G G G+ G PG+ G G PG PGP G GPPG + + A Sbjct: 681 GLPGIPGEEGKEGRDGKPGPPGEP----GKAGEPGLPGPEGARGPPGFKGHTGDSGAPGP 736 Query: 1046 R--------PGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGD 1097 R PG GLPG G GP G +G GP GPPG+ GE G G Sbjct: 737 RGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGK------NGSPGSPGEPGPSGT 790 Query: 1098 AGQKGERGEPGGGGFFGSSLP-GPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIG 1156 GQKG +GE G G G P GPPG PG +G PG G G+ G+PG G +G PGI Sbjct: 791 PGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKP--GEPGFKGERGDPGI- 847 Query: 1157 YEGRQGPPGPPGPPGPPSFPGPHRQT-----ISVPGPPGPPGPPGPPGTMG 1202 +G +GPPG G PG P PG T +PG GP GPPGPPG G Sbjct: 848 -KGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPG 897 Score = 329 bits (844), Expect = 1e-89 Identities = 212/505 (41%), Positives = 241/505 (47%), Gaps = 76/505 (15%) Query: 494 PGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGP--------------- 536 PG + + G PG +EG G KG+ G PG+PGPPG AGP Sbjct: 569 PGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQ 628 Query: 537 ------PGSPCLPGPPGLPCPVSPLGPAG----PALQTVPGPQGPPGPPGRDGTPGRDGE 586 PG P GPPG P P G AG P +Q PG +GPPGP G G PG GE Sbjct: 629 KGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGE 688 Query: 587 PGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKL 646 G G DGKPG G G G PG GP+G +G PG +G G G PGP G S + Sbjct: 689 EGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGF--KGHTGDSGAPGPRGES---GAM 743 Query: 647 TFIDMEG-SGFGGDLEAL--RGPRGFPGPPGPPGVPGLPGEPGRFGV-NSSDVPGPAGLP 702 EG G GD +GP+G GPPG G PG PGEPG G G G P Sbjct: 744 GLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSP 803 Query: 703 GVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGES 762 G+PG GP G PG PG G PG+EG PG+ G+ G GE G PG KG KG PG G G+ Sbjct: 804 GLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDP 863 Query: 763 GL------------AGAPGPAGPPGPPGPPGPPG-PGLPAGFDDME-------GSGGPFW 802 G+ G PG GP GPPGPPG PG PGL ME G Sbjct: 864 GIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQL 923 Query: 803 STARSADGPQGPPG-LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKG 861 T + Q PP + +G PG PG PG G G G G PG PG+ G+ GP GP G Sbjct: 924 ETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIG 983 Query: 862 DRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFA--GFPG 919 +G RG KGDPG GVG G GPPG +PG G PG+A G PG Sbjct: 984 PKGERGAKGDPGAPGVGLRGEMGPPG-----------------IPGQPGEPGYAKDGLPG 1026 Query: 920 PAGPKGNLGSKGERGSPGPKGEKGE 944 GP+G G G G PGP G G+ Sbjct: 1027 IPGPQGETGPAGHPGLPGPPGPPGQ 1051 Score = 249 bits (635), Expect = 2e-65 Identities = 181/534 (33%), Positives = 219/534 (41%), Gaps = 139/534 (26%) Query: 426 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTT- 484 G GD G RE + G A P LP PP + P + G D + +Q Sbjct: 576 GFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHP 635 Query: 485 -----VASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAG-- 535 + G PG+D ++ G G KEG G +G G PG+PG G+ G Sbjct: 636 GVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRD 695 Query: 536 ----PPGSPCLPGPPGLPCPVSPLGPAG----------------------PALQTVPG-- 567 PPG P G PGLP P GP G P + +PG Sbjct: 696 GKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKD 755 Query: 568 ----------PQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDK 617 PQGP GPPG++G+PG GEPG G G+ G G G PG PG +GP+G Sbjct: 756 GDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPP 815 Query: 618 GDPGVGERGPPGPQGPPGPPG-PSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPP 676 G+PG E+G PG +G PG PG P F+ ++ GD ++G +G PG G P Sbjct: 816 GEPG--EKGVPGKEGVPGKPGEPGFKGER------------GD-PGIKGDKGPPGGKGQP 860 Query: 677 GVPGLPGEPGRFGV-NSSDVPGPAGLPGVPGREGPPGFPGL------------------- 716 G PG+PG G G+ +PG G G PG G PGFPGL Sbjct: 861 GDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELG 920 Query: 717 -------------------------PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKG 751 PGPPGPPG++G PGR G G G G G +G G Sbjct: 921 KQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSG 980 Query: 752 APGPAGARGESGLAGAPGPA-----GPPGPPGPPGPPG---PGLPAGFDDMEGSGGPFWS 803 GP G RG G GAPG GPPG PG PG PG GLP Sbjct: 981 PIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLP--------------- 1025 Query: 804 TARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREG-IAGP 856 G GP G G G PG+PG PG G+ F L R G + GP Sbjct: 1026 ------GIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKGP 1073 Score = 33.9 bits (76), Expect = 1.2 Identities = 56/218 (25%), Positives = 73/218 (33%), Gaps = 37/218 (16%) Query: 46 PEPQGP--LPVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAP 103 P PQGP LP P + G PG P P + E G P A P Sbjct: 674 PGPQGPSGLPGIPGEE---------GKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGF 724 Query: 104 EENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQE 163 + + GA G + +P + +T P GP GP P + Sbjct: 725 KGHTGDSGAPGPRGESGAMGLPG--QEGLPGKD---GDT----GPTGPQGPQGPRGPPGK 775 Query: 164 NGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWAP-LTGPSVPP--PSSERISE 220 NG S G P PG T P S G P P GP PP P + + Sbjct: 776 NG-----SPGSPGEPGPSGT-----PGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPG 825 Query: 221 EVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQ 258 + G+ G+P + + D G+ GP GQ Sbjct: 826 KEGVPGKPGEPG----FKGERGDPGIKGDKGPPGGKGQ 859 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 504 bits (1297), Expect = e-142 Identities = 377/1049 (35%), Positives = 439/1049 (41%), Gaps = 280/1049 (26%) Query: 411 VSPMHCLDEEGDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSS 470 V P E+GD DGA G G + G+ + PP P G Sbjct: 1438 VGPPGKKGEKGDSEDGAPGLPG------------QPGSPGEQGPRGPPGAIGPKGDRGFP 1485 Query: 471 TEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPG--GRVKEGGLKGQKGEPGVP 528 + E E+ G++ LPG G PG GR E G G+ G+P V Sbjct: 1486 GPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVV 1545 Query: 529 GP----------------------------------PGRAGPPGSPCLPGPPGLPCPVSP 554 GP PG GP G P GP GL P Sbjct: 1546 GPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGP 1605 Query: 555 LGPAGPALQTV----PGPQGPPGPPGRDGTPGRDGE---PGDPGEDGKPGDTGPQGFPGT 607 G +GP + PGP GP GP GRDG G G+ PGDPG GK G+ G +G PG Sbjct: 1606 PGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGV 1665 Query: 608 PGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDL 660 G VG KGD+GDPG G GP G +G PGPPGP R + +G G Sbjct: 1666 RGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGR--------LVDTGPGARE 1717 Query: 661 EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNS-SDVPGPAGLPGV--------------- 704 + G RG GP GP G PGLPG PG G+ PGP G PGV Sbjct: 1718 KGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGL 1777 Query: 705 ---------------------------PGREGPPGF---PGLPGPPGPPGREGPPGRTGQ 734 PGR+G PG GLPGP GPPG G PG G+ Sbjct: 1778 DGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGK 1837 Query: 735 ---KGSLGEAGAPGHKGSKGAPGPAGA---------RGESGLAGAPGPAGPPGPPGPPGP 782 G GE G PG G KG G +GA +GE G G GP GPPG PGP GP Sbjct: 1838 PGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGP 1897 Query: 783 PG---PGLPAG------------------------------------------------- 790 PG PG+P G Sbjct: 1898 PGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALR 1957 Query: 791 --FDDMEGSGGPFWSTARSADGP------QGPPGLPGLKGDPGVPGLPGAKGEVGADGVP 842 + + S G F GP QGPPG G G PG GL G +G+ G G P Sbjct: 1958 EIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPP 2017 Query: 843 ----------------------GFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG---- 876 G PGLPGR G G G G+RG RGEKG+ G+ G Sbjct: 2018 GLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGP 2077 Query: 877 VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGP------EGRPGFAGFPGPAGPKGNLGSK 930 G PG PGPPGPPGP V V E + GP +G PG G GP G +G G K Sbjct: 2078 PGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIK 2137 Query: 931 GERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGP---YGRPGYKGEIGF 987 G+RG PGP+G+ G PG + G GP +G G G RGPPGP +G PG G G Sbjct: 2138 GDRGEPGPRGQDGNPG--LPGERGMAGP--EGKPGLQGPRGPPGPVGGHGDPGPPGAPGL 2193 Query: 988 PGRPGRPGMNGLKGEKGEPGDASLGF----GMRGMPGPPGPPGPPGPPGTPVYDSNVFAE 1043 G G G +GLKGE GE G G G G+PGPPGP G GP G+P V E Sbjct: 2194 AGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQV-GE 2252 Query: 1044 SSRP---------------GPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFL------ 1082 + +P G PG+PG+ G PGP G KGE GP G PGQ Sbjct: 2253 TGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEK 2312 Query: 1083 ----QLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE 1138 L ++ GE G +GD G G RGE G G G PG PG G +G PG G KG+ Sbjct: 2313 GAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGE--PGDPGEDGQKGAPGPKGFKGD 2370 Query: 1139 SIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGP--HRQTISVPGP-------- 1188 G PG PGP GPPG+ +G G PG PG PG FPG R + PGP Sbjct: 2371 PGVGVPGSPGPPGPPGV--KGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAG 2428 Query: 1189 -------PGPPGPPGPPGTMG--ASSGVR 1208 PGP GPPGPPG++G +SG++ Sbjct: 2429 PPGREGIPGPLGPPGPPGSVGPPGASGLK 2457 Score = 495 bits (1274), Expect = e-139 Identities = 364/988 (36%), Positives = 429/988 (43%), Gaps = 220/988 (22%) Query: 409 PQVSPMHCLDEEGDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGG 468 P+ P++C G G+ G +G LR + G P LP P G Sbjct: 1244 PEPCPVYC-------PKGQKGEPGE-MG-----LRGQVGPPGDPGLPGRTGAPGPQGPPG 1290 Query: 469 SSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPG 526 S+T S G PG+ GS PG R G G +G KGEPG Sbjct: 1291 SATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPG 1350 Query: 527 VPGP---------PGRAGPP------------GSPCLPGPPGLPCP-------------- 551 PG PGR G P G P GPPGLP Sbjct: 1351 APGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGP 1410 Query: 552 -------VSPLGPAGPALQTVPGPQGPPGPPGRDGTPG--RDGEPGDPGEDGKPGDTGPQ 602 ++P P P L PGPQGP GPPG+ G G DG PG PG+ G PG+ GP+ Sbjct: 1411 PGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPR 1470 Query: 603 GFPGTPGDVGPKGDKGDPG-------VGERGPPGP---------------QGPPGPPGPS 640 G PG +GPKGD+G PG GERGPPGP +GP GPPGP+ Sbjct: 1471 ---GPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPT 1527 Query: 641 FRHDKLTFIDMEG--SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGP 698 R + G + G + +G +G GP GP G G+ GE G G+ PGP Sbjct: 1528 GRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGP 1587 Query: 699 AGLP------GVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA 752 G P G+ GR GPPG G PG G PGR GPPG G +G GE G G +G G Sbjct: 1588 KGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGD 1647 Query: 753 PGPAGARGESGLAGAP---------------------------GPAGPPGPPGPPGPPGP 785 PG G GE GL GAP GP G G PGPPGPPG Sbjct: 1648 PGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGR 1707 Query: 786 GLPAGFDDMEGSGGPFWSTARSADGPQGPPGLP---------GLKGDPGVPGLPGAKGEV 836 + G E G P GP+G PGLP G +G PG G PG +G Sbjct: 1708 LVDTGPGARE-KGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPA 1766 Query: 837 GADGVPGFPGLPGREGI---AGPQGPKGDRGSRGEKGDPGKDGV----GQPGLPGPPGPP 889 G G G PGL GR G+ G GP G G+ G+ GDPG+DG+ G+ GLPGP GPP Sbjct: 1767 GEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPP 1826 Query: 890 GPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIF 949 G + +DG + G G PG G G G KG+ G+ G G GPKGE+G PG I Sbjct: 1827 G-LPGKPGEDGKP-GLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPG-IL 1883 Query: 950 SPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG----- 1004 P G P G G+ GF G PG G G +GE G G G PG GL+GE G Sbjct: 1884 GPQGPPGLPGPVGPPGQ-GFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNV 1942 Query: 1005 ------------------EPGDASLGF---------GMRGMPGPPGPPGPPGPPGTPVYD 1037 E D S G G +G G GPPG GP G P + Sbjct: 1943 DRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFP-GE 2001 Query: 1038 SNVFAESSRPGPPGLP----GNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKG 1093 + + PGP G P G +GPPGP G GE G PG PG EA GE+G Sbjct: 2002 RGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERG 2061 Query: 1094 DRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPR--------------GYPGIPGPKGE- 1138 +RG+ G++GE+G G G G+ PGPPGPPGP+ G PG+ G KGE Sbjct: 2062 ERGEKGERGEQGRDGPPGLPGT--PGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEP 2119 Query: 1139 ------------------SIRGQPGPPGPQGPPGI----GYEGRQGPPGPPGPPGPPSFP 1176 RG+PGP G G PG+ G G +G PG GP GPP Sbjct: 2120 GSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPV 2179 Query: 1177 GPHRQTISVPGPPGPPGPPGPPGTMGAS 1204 G H PGPPG PG GP G G S Sbjct: 2180 GGHGD----PGPPGAPGLAGPAGPQGPS 2203 Score = 479 bits (1233), Expect = e-135 Identities = 383/1082 (35%), Positives = 459/1082 (42%), Gaps = 248/1082 (22%) Query: 418 DEEGDDSDGASGDSGSGLGDARELLREETGAA--LKPRLP-------APPPVTTPPLAGG 468 D D G GDSG+ + R+ + E GA L P+ P PP P + GG Sbjct: 1849 DPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGG 1908 Query: 469 SSTEDSRSEEVE--EQTTVASLGAQTLPGS-------------------DSVSTWD---- 503 + + R E EQ G + PGS + V TWD Sbjct: 1909 TGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSG 1968 Query: 504 ----------------GSVRTPG-----GRVKEGGLKGQKGEPGVPGPPGRA----GPPG 538 G PG G E GLKG +G+PG GPPG A GPPG Sbjct: 1969 SFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPG 2028 Query: 539 ------SPCLPGPPGLPCPVSPLGPAG-PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPG 591 P PG PGLP +G AG P + G +G G GRDG PG G PG PG Sbjct: 2029 PSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPG 2088 Query: 592 -----------------EDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGP 633 E G PG G +G PG+ GD GPKGD+G PG+ G+RG PGP+G Sbjct: 2089 PPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQ 2148 Query: 634 PGPPG-PSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNS 692 G PG P R G L+GPRG PGP G G PG PG PG G Sbjct: 2149 DGNPGLPGER----------GMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAG--P 2196 Query: 693 SDVPGPAGLPGVPGREGPPG--------FPGLPGPPGPPGREGP---PGRTGQKGSLGEA 741 + GP+GL G PG GPPG GLPGPPGP G GP PG GQ G G+ Sbjct: 2197 AGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKP 2256 Query: 742 GAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGP---GLPA--------- 789 GAPG G+ G G G+ G G G PGP GP G PGP G PG GLP Sbjct: 2257 GAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPG 2316 Query: 790 -------------GFDDMEGSGGPFWSTARSA-------DGPQGPPGLPGLKGDPGV--- 826 G + G G R+ DG +G PG G KGDPGV Sbjct: 2317 GLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVP 2376 Query: 827 -----PGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKG---DPGKDGV- 877 PG PG KG++G G+PG PG+ G G GP+G G G GE+G PG++G+ Sbjct: 2377 GSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIP 2436 Query: 878 ---GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGP------------EGRPGFAG---FPG 919 G PG PG GPPG ++ + +PGP +GRPG G G Sbjct: 2437 GPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTG 2496 Query: 920 PAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDG--GALG-------------------- 957 P G +G G KG+ GS G KG+KG+ I P G GA G Sbjct: 2497 PPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDN 2556 Query: 958 --PAQKGAKGEPG---------FRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEP 1006 P KG+KGEPG RG GP G+PG G G PG PG+ G+ G++GEKG+ Sbjct: 2557 GDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDV 2616 Query: 1007 GDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGP------PG 1060 G G RG+ G G G G G + E+ PG PGL G++G PG Sbjct: 2617 GF----MGPRGLKGERGVKGACGLDG----EKGDKGEAGPPGRPGLAGHKGEMGEPGVPG 2668 Query: 1061 PKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGP 1120 GA G+ G GP G FD G+ G +GD G+KGERG PG GGF G S G Sbjct: 2669 QSGAPGKEGLIGPKGDRGFD---------GQPGPKGDQGEKGERGTPGIGGFPGPS--GN 2717 Query: 1121 PGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHR 1180 G GP G PG GP+G G G G +GPPG G G PG PG G Sbjct: 2718 DGSAGPPGPPGSVGPRGPE--GLQGQKGERGPPGERVVGAPGVPGAPGERGE-------- 2767 Query: 1181 QTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVR 1240 G PGP GP G G + RQ M H +G F+A Sbjct: 2768 -----QGRPGPAGPRGEKGEAALTEDDIRGFVRQEM--SQHCACQGQ--FIASGSRPLPS 2818 Query: 1241 VQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILA 1300 QL A L E + P + + + Y E+ P A PW +DD + Sbjct: 2819 YAADTAGSQLHAVPVLRVSHAEEEERVPPEDDEYSEYSEYSVEEYQDPEA-PWDSDDPCS 2877 Query: 1301 SP 1302 P Sbjct: 2878 LP 2879 Score = 373 bits (957), Expect = e-103 Identities = 246/580 (42%), Positives = 281/580 (48%), Gaps = 63/580 (10%) Query: 671 GPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPG 730 GP V GL + + P P + G++G PG GL G GPPG G PG Sbjct: 1219 GPSLDQAVSGLATALCQASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPG 1278 Query: 731 RTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAG 790 RTG G G G+ KG +G PG G G G AG PG G PG G PG PGP G Sbjct: 1279 RTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPG 1338 Query: 791 FDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGR 850 G G + + G PGLPG KGDPG G PG +G +G G G PGLPG Sbjct: 1339 ERGPRGPKGEPGAPGQVIGGE--GPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPG- 1395 Query: 851 EGIAGPQGPKGDRGSRGEKGDPGKDGV--GQPGLPGPPGPPGPVVYV------SEQDGSV 902 +G KGDRG RG G PG+ G+ G+PGLPG PG PGP V E+ S Sbjct: 1396 ---TAMKGDKGDRGERGPPG-PGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSE 1451 Query: 903 LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKG 962 PG G+PG G GP GP G +G KG+RG PGP GE GE G P G A G Sbjct: 1452 DGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGE-RGPPGPAGSRGLPG 1510 Query: 963 AKGEPGFRGPPGPYGRPGYKGEIGFPGRPG-----RPGMNGLKGEKGEPGDASL--GFGM 1015 G PG +GP GP G G +GE G PGRPG P + G KGEKG+ G A G+ Sbjct: 1511 VAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGV 1570 Query: 1016 RGMPGP-----PGPPGPPGPPGT-----------PVYDSNVFAESSRPGPPGLPGNQGPP 1059 +G GP PG PGP G PG P DS E PG PG PG GP Sbjct: 1571 QGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPR 1630 Query: 1060 GPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPG 1119 G G GE G GPPG E ++G G RG G+KG++G+PG G GS PG Sbjct: 1631 GRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGS--PG 1688 Query: 1120 PPGPPGPRGYPGIPGPKGESI--------------RGQPGPPGPQGPPGI-GYEGRQGPP 1164 GP G RG PG PGP G + RGQ GP GP+G PG+ G G +G Sbjct: 1689 SSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIE 1748 Query: 1165 GPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGAS 1204 G GPPGP PG V GP G G GPPG G S Sbjct: 1749 GFRGPPGPQGDPG-------VRGPAGEKGDRGPPGLDGRS 1781 Score = 148 bits (374), Expect = 3e-35 Identities = 103/262 (39%), Positives = 118/262 (45%), Gaps = 47/262 (17%) Query: 952 DGGALGPAQKG---AKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGD 1008 DG +L A G A + F P P P Y + G+ G PG GL+G+ G PGD Sbjct: 1218 DGPSLDQAVSGLATALCQASFTTQPRPEPCPVYCPK----GQKGEPGEMGLRGQVGPPGD 1273 Query: 1009 ASLGFGMRGMPGPPGPPGPPGPPG--TPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKG 1066 G+PG G PGP GPPG T + RPG PG GN G PG G KG Sbjct: 1274 P-------GLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKG 1326 Query: 1067 EVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGG-GFFGSSLPGPPGPPG 1125 G PGP +G+ G+RG G KGE G PG G G LPG G PG Sbjct: 1327 SPGLPGP---------------RGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPG 1371 Query: 1126 PRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISV 1185 P G PG GP G+ PGP GP G PG +G +G G GPPGP Sbjct: 1372 PSGPPGPRGPLGD-----PGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIA------- 1419 Query: 1186 PGPPGPPGPPGPPGTMGASSGV 1207 PG PG PG PG+ G V Sbjct: 1420 ---PGEPGLPGLPGSPGPQGPV 1438 Score = 144 bits (362), Expect = 8e-34 Identities = 134/397 (33%), Positives = 159/397 (40%), Gaps = 59/397 (14%) Query: 373 RGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDP-QVSPMHCLDEEGDDSDGASGDS 431 RG +PG + G A P +G+ L P V P +GD D G Sbjct: 2412 RGEMGQPGPS---GERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLP 2468 Query: 432 GSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQ 491 G +R E G +P P +T PP + G E E+ V S G + Sbjct: 2469 GPRGERGEPGIRGEDG---RPGQEGPRGLTGPPGSRG---------ERGEKGDVGSAGLK 2516 Query: 492 TLPGSDSVSTWDGSVRTPGGRVKEGG---LKGQKGEPGVPGPPGRAGPPGSPCLPGPPGL 548 G +V R G + E G L G KG G G PG G G P G GL Sbjct: 2517 GDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGL 2576 Query: 549 PCPVSPLGPAG-PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE--------------- 592 P LGP G P +PG PG PG+DG PG GE GD G Sbjct: 2577 PGLRGLLGPQGQPGAAGIPGD---PGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGA 2633 Query: 593 ---DGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPG-------PSF 641 DG+ GD G G PG PG G KG+ G+PGV G+ G PG +G GP G P Sbjct: 2634 CGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGP 2693 Query: 642 RHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSD----VPG 697 + D+ + G GG GP G G GPPG PG G G G+ PG Sbjct: 2694 KGDQGEKGERGTPGIGG----FPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPG 2749 Query: 698 P--AGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRT 732 G PGVPG G G G PGP GP G +G T Sbjct: 2750 ERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALT 2786 Score = 32.7 bits (73), Expect = 2.7 Identities = 48/187 (25%), Positives = 61/187 (32%), Gaps = 14/187 (7%) Query: 77 PGSPEPPSELLEDGQDTPTSAESPDAPEENIAG-VGAEILNVAKGIRSFVQLWNDTVPTE 135 PG P PP L++ G E D +E G G L A G R P Sbjct: 1699 PGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQG 1758 Query: 136 SLARAETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSP 195 + P G GP +G P PS P +AG P P Sbjct: 1759 DPG------VRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGD-PGRDGLP 1811 Query: 196 PSLGRPWAPLTGPSVPP--PSSERISEEVGLLQLLGDP--PPQQVTQTDDPDVGLAYVFG 251 G P GPS PP P + GL G+P P + + + D G + G Sbjct: 1812 GLRGEQGLP--GPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREG 1869 Query: 252 PDANSGQ 258 D G+ Sbjct: 1870 RDGPKGE 1876 >gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] Length = 1860 Score = 490 bits (1262), Expect = e-138 Identities = 371/982 (37%), Positives = 431/982 (43%), Gaps = 226/982 (23%) Query: 408 DPQVSPMHCLDEEGDDSDGASGDSG-SGLGD-----ARELLREETGAALKPRLPAPPPVT 461 DP +SP G DGA GD G GL R+ + G A P P Sbjct: 677 DPGLSP-------GKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPE 729 Query: 462 TPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLK 519 P A G V + S G LPG + DG PG K G G+ Sbjct: 730 GSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMP 789 Query: 520 GQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP------------------- 560 G G G GPPG G PG LPGPPG+P + LG GP Sbjct: 790 GFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEP 849 Query: 561 ------ALQTVPG------------PQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQ 602 Q VPG QG PG PG G PG G+ GD G G PG GP+ Sbjct: 850 GLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPE 909 Query: 603 GFPGT---PGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDME 652 GFPG PGD GP+G KG PG G+ GP G +GP GPPG Sbjct: 910 GFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAP------------ 957 Query: 653 GSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFG-------------------VNSS 693 LE G +GFPG PG GV G PG+PGR G V Sbjct: 958 ------GLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEK 1011 Query: 694 DVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAP 753 G G PGVPG +G G PG+PG G PG GP G G +G G GA G +G +G Sbjct: 1012 GDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPD 1071 Query: 754 GPAGARGESGLAGAPGPAGPPGPPGP---------------PGPPGPGLPAGFDDMEGSG 798 GPAG +G GL G PGP G PG PG PG PGP P G + G Sbjct: 1072 GPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEP 1131 Query: 799 GPFWSTARSADGPQGPPGL------PGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREG 852 GP + GP GPPG PG G+PG+PG G KG++G G PG GL G+ G Sbjct: 1132 GP-----QGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRG 1186 Query: 853 ---IAGPQGPKGDRGSRGEKGDPGKDGV----GQPGLPGPPGPPGPVVYVSEQDGSVLSV 905 + G GP G G +G++GDPG DG GQ GL G GPPGP V V Sbjct: 1187 EPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPP--------GVTGV 1238 Query: 906 PGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDG--GALGPA---- 959 GPEG+ G G G G KG G +G+ G G G+ G PG+ P G G+LGP Sbjct: 1239 RGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTP-GPKGSRGSLGPTGAPG 1297 Query: 960 QKGAKGEPGFRG------------PPGPYGRPGYKGEIGF----PGRPGRPGMNGLKGEK 1003 + GA+GEPG G PPGP G G +GE G PG PG G G +G++ Sbjct: 1298 RMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDR 1357 Query: 1004 GEPGDASLGF-----GMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR--------PGPP 1050 GEPGD G+RG PG G PG PGP G P + AE + PG Sbjct: 1358 GEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRR 1417 Query: 1051 GLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKG---ERGEP 1107 G+ G QG PGP+G G G G G +A +GE+GD GD G G +RG P Sbjct: 1418 GVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNP 1477 Query: 1108 GGGGFFG----------SSLPGPPGPPGPRGYPG---IPGPKGE-SIRGQPGPPG----- 1148 G G G S LPG GPPG RG G +PG +GE +GQPG G Sbjct: 1478 GVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFP 1537 Query: 1149 -------PQGPPG-IGYEGRQGPPGPPGPPG------------PPSFPGPH-----RQTI 1183 P+GPPG IG++G QGP GPPG G P PGP R Sbjct: 1538 GMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDW 1597 Query: 1184 SVPGPPGPPGP---PGPPGTMG 1202 + GP GPPGP PGPPG G Sbjct: 1598 GLQGPRGPPGPRGRPGPPGPPG 1619 Score = 489 bits (1258), Expect = e-137 Identities = 346/882 (39%), Positives = 394/882 (44%), Gaps = 144/882 (16%) Query: 438 ARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSD 497 AR++ + PR P P TTP L + S S + T + L GS Sbjct: 563 ARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSP----RPTSSGYSIFHLAGST 618 Query: 498 SVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGP 557 G P G + GL G G PG+PG PG GP G P G PGLP P G Sbjct: 619 PFPLLMG----PPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQ 674 Query: 558 AG-PALQT------------VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGP--- 601 G P L +PG G PGPPGR G G G G PGE G+PG G Sbjct: 675 KGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGA 734 Query: 602 ------QGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS 654 QG PG GD GPKG +G G+ G G PG G G PG + K M Sbjct: 735 KGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGK-----MGMP 789 Query: 655 GFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFG----VNSSDVPGPAGLPGVPGREGP 710 GF G + RGP G G PG G+PG PG PG G + PGP G+ G+ G G Sbjct: 790 GFPG-VFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGE 848 Query: 711 PGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGP 770 PG G G G PG G PG G KGS G PG G++G PGP G G+ G G PGP Sbjct: 849 PGLKGDKGEQGVPGVSGDPGFQGDKGS---QGLPGFPGARGKPGPLGKVGDKGSIGFPGP 905 Query: 771 AGPPGPPGPPGPPGPGLPAGFDDMEGS---GGPFWSTARSAD-GPQGPPGLPGLKGDPGV 826 GP G PG GPPG P G G+ GP D GP GPPG PGL+G PG Sbjct: 906 PGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGR 965 Query: 827 PGLPGAKGEVGADGVPGFPGLPGREGIAGPQ---------------GPKGDRGSRGEKGD 871 G P G G DGV G PG PGR G G Q G KGDRG G G Sbjct: 966 KGFP---GRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGV 1022 Query: 872 PG-KDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFP------------ 918 PG K +G PG+PG G PG PGP+G PG G P Sbjct: 1023 PGPKGSMGHPGMPGGMGTPGE--------------PGPQGPPGSRGPPGMRGAKGRRGPR 1068 Query: 919 GPAGPKGNLGSKGERGSPGPKGEKGEPGSI-FSPDGGALG-------------PAQKGAK 964 GP GP G GS+G +G PGP+G G PG + + G LG P KG Sbjct: 1069 GPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLP 1128 Query: 965 GEPGFRGPPGPYGRPGY------KGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGM 1018 GEPG +GP GP G PG G +G PG PG GM G G G PG+ L G RG Sbjct: 1129 GEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGL-IGQRGE 1187 Query: 1019 PGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFP 1078 PG G GP GP G G PG G G G +G GE GPPGPPG Sbjct: 1188 PGLEGDSGPMGPDGL----------KGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTG 1237 Query: 1079 FDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE 1138 + ++ +GEKG G G KG +G+ G G G PGPPG PGP+G G GP Sbjct: 1238 VRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGD--PGPPGTPGPKGSRGSLGP--- 1292 Query: 1139 SIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGP 1197 G PG G QG PG+ GY+G +G GP GPPGP G + GPPGPPG GP Sbjct: 1293 --TGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGP 1350 Query: 1198 PGTMG-----------ASSGVRLWATRQAMLGQV-HEVPEGW 1227 G G GV+ + GQ H P GW Sbjct: 1351 VGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGW 1392 Score = 449 bits (1154), Expect = e-125 Identities = 315/778 (40%), Positives = 357/778 (45%), Gaps = 149/778 (19%) Query: 489 GAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSPCLPGPP 546 G+Q LPG G + G + G G G +G PG GPPG GP G PG Sbjct: 874 GSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGAR 933 Query: 547 GLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPG---------DPGEDGKPG 597 GLP P LGP G GP GPPG PG +G PGR G PG +PG+ G+PG Sbjct: 934 GLPGPRGQLGPEGDE-----GPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPG 988 Query: 598 DTGPQGFPG---------------------TPGDVGPKGDKGDPGV----GERGPPGPQG 632 G QGF G PG GPKG G PG+ G G PGPQG Sbjct: 989 PVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQG 1048 Query: 633 PPGPPGP-SFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVN 691 PPG GP R K G G+ +G RG GPPGP G PG PG+ G G Sbjct: 1049 PPGSRGPPGMRGAKGRRGPRGPDGPAGE----QGSRGLKGPPGPQGRPGRPGQQGVAGER 1104 Query: 692 SSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGP---PGRTGQKG---SLGEAGAPG 745 G G PG+PG GPPG GLPG PGP G +GP PG G KG ++GE G PG Sbjct: 1105 GH--LGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPG 1162 Query: 746 HKGSKGAPGPAGA---------RGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEG 796 G KG GP G RGE GL G GP GP G G G PGP G EG Sbjct: 1163 EAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEG 1222 Query: 797 SGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPG------LPGR 850 G DGP GPPG+ G++G G G G KG GA G G+ G +PG Sbjct: 1223 LMGE--------DGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGD 1274 Query: 851 EGIAGPQGPKGDRGSRGEKGDPGKDGV-GQPGLPG---------PPGPPGPVVYVSEQ-- 898 G G GPKG RGS G G PG+ G G+PGL G P GPPGP EQ Sbjct: 1275 PGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGE 1334 Query: 899 DGSVLSVPGP------------EGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPG 946 DG PGP G PG G+PG G +G G G++G PG G +G PG Sbjct: 1335 DGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPG 1394 Query: 947 SIFSP--------DGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNG 998 S G A P ++G +G G GP G GR G +G G G PGR G G Sbjct: 1395 PKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAG 1454 Query: 999 LKGEKGEPGDAS-LG-FGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPG---PPG-- 1051 +GE+G+ GD +G G RG PG G PG GPPG ES PG PPG Sbjct: 1455 QQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFK-------GESGLPGQLGPPGKR 1507 Query: 1052 -------LPGNQGPPGPKGAKGE------------VGPPGPPGQFPFDFLQLEAE---MK 1089 LPGNQG PG KG G+ GP GPPG F +Q + Sbjct: 1508 GTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLM 1567 Query: 1090 GEKGDRGDAGQKGERGEPGGGGFFGS----SLPGPPGPPGPRGYPGIPGPKGESIRGQ 1143 G++G G G G G PG G GS L GP GPPGPRG PG PGP G I+ Q Sbjct: 1568 GKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGPIQLQ 1625 Score = 396 bits (1018), Expect = e-110 Identities = 309/864 (35%), Positives = 361/864 (41%), Gaps = 163/864 (18%) Query: 457 PPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG 516 P + T P A +S +S ++T +S LP V V R E Sbjct: 365 PKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPAEK 424 Query: 517 GLKGQKGEPGVPGPPGRAGPPGSPCLPGP-PGLPCPVSPLG-----PAGPALQTVPGPQG 570 ++ G P P P R PP + P P L + + PA T P Sbjct: 425 PIQRNPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPF 484 Query: 571 PPGPPGRDGTPGRDGEPGDPGEDGKP--GDTGPQGFPG--TPGDVGPKGDK---GDPGVG 623 TPG P P G + P+ P TPG P G K G Sbjct: 485 TALSSSPAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSA-PTGSKKPIGSEASK 543 Query: 624 ERGPPGPQGPPGP--PGPSFRHDKLTFIDMEGS--------------------------- 654 + GP P P PG + R L+ + S Sbjct: 544 KAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPR 603 Query: 655 --GFGGDLEALRGPRGFP---GPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVP---- 705 G + L G FP GPPGP G GLPG PG LPG+P Sbjct: 604 PTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPG--------------LPGLPGIPG 649 Query: 706 -----GREGPPGFPGLPGPPGPPGREGPPG------RTGQKGSL------GEAGAPGHKG 748 G GP G PGLPGPPG G++G PG G KG + G G PG KG Sbjct: 650 ARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKG 709 Query: 749 SKGAPGPAGARGES---------GLAGAPGPAGPPGPPGPPGPPGP----GLPAGFDDME 795 KG PGPAG GE G G PG G PGP G PGP G GLP F Sbjct: 710 HKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPG 769 Query: 796 GSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAG 855 G G G PG PG+ G+ G PGL G GE+G G PG PGL G G+ G Sbjct: 770 SDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLG 829 Query: 856 P---QGPKGDRGSRGEKGDPG-KDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGR 911 P GPKG +G G G+PG K G+ G+PG G PG G +G Sbjct: 830 PIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPG-----------FQGDKGSQGL 878 Query: 912 PGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSP-DGGALG----------PAQ 960 PGF G G GP G +G KG G PGP G +G PG I P D G G P Sbjct: 879 PGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGP 938 Query: 961 KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPG-------DASLGF 1013 +G G G GP GP G PG +G+ G G PGRPG++G+KGE G+PG +GF Sbjct: 939 RGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGF 998 Query: 1014 -------------GMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPG 1060 G RGM GPPG PGP G G P + PGP G PG++GPPG Sbjct: 999 IGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGM-GTPGEPGPQGPPGSRGPPG 1057 Query: 1061 PKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGP 1120 +GAKG GP GP G GE+G RG G G +G PG G G + G Sbjct: 1058 MRGAKGRRGPRGPDGP------------AGEQGSRGLKGPPGPQGRPGRPGQQG--VAGE 1103 Query: 1121 PGPPGPRGYPGIPGPKG-ESIRGQPGPPGPQGPPG-IGYEGRQGPPGPPGPPGPPSFPGP 1178 G G RG+PGIPGP G +G PG PGPQGP G IG G GP GPPG G P PG Sbjct: 1104 RGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPG- 1162 Query: 1179 HRQTISVPGPPGPPGPPGPPGTMG 1202 + G GP G PG G +G Sbjct: 1163 ---EAGMKGDLGPLGTPGEQGLIG 1183 Score = 390 bits (1001), Expect = e-108 Identities = 362/1054 (34%), Positives = 426/1054 (40%), Gaps = 231/1054 (21%) Query: 330 AASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPGAGLFVAQAG 389 + +F L G+W HLAL + G V L C + + L R L+PG G F+ Sbjct: 144 SVAFDLDMHDGRWHHLALELRGRTVTLVTACGQRRVPVLLPFHRDPALDPG-GSFLFGKM 202 Query: 390 GADPDKFQGVIAELKVRRDPQVSPMHC--LDEEGDDSDG--------ASGDSGSGLGDAR 439 +F+G + + + QV+ +C L ++ +D S DSG Sbjct: 203 NPHAVQFEGALCQFSIYPVTQVAHNYCTHLRKQCGQADTYQSPLGPLFSQDSGRPFTFQS 262 Query: 440 E--LLREETGAALKPRLPAPPPVTTP--PLAGGSSTEDSRSEEVEEQTTVASLG-AQT-- 492 + LL E P L + P P +A + T+ R+ +A G AQT Sbjct: 263 DLALLGLENLTTATPALGSLPAGRGPRGTVAPATPTKPQRTSPTNPHQHMAVGGPAQTPL 322 Query: 493 LPGSDSVS---------TWDGSVRTPGGRV-----KEGGLKGQKGEPGVPGPPGRA-GPP 537 LP S S + GS RTP K K K P P P + P Sbjct: 323 LPAKLSASNALDPMLPASVGGSTRTPRPAAAQPSQKITATKIPKSLPTKPSAPSTSIVPI 382 Query: 538 GSP--------------CLP-----GPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRD 578 SP LP P P P PA +Q PG PP P R Sbjct: 383 KSPHPTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPAEKPIQRNPGMPRPPPPSTRP 442 Query: 579 --------------------------------------------------GTPGRDGEPG 588 TPG Sbjct: 443 LPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSPAPTPGSTRSTR 502 Query: 589 DPGEDGKP--GDTGPQGFPG--TPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHD 644 P P G + P+ P TPG P G K G GP+ P P P Sbjct: 503 PPATMVPPTSGTSTPRTAPAVPTPGS-APTGSKKPIGSEASKKAGPKSSPRKPVPLRPGK 561 Query: 645 KLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP-------- 696 + + DL PR P P L P +F ++SS P Sbjct: 562 AARDVPL------SDLTTRPSPR--QPQPSQQTTPALVLAPAQF-LSSSPRPTSSGYSIF 612 Query: 697 ------------GPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAP 744 GP G G G GPPG PGLPG PG G GPPG G G G GA Sbjct: 613 HLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAK 672 Query: 745 GHKGSKG-APGPA--GARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPF 801 G KG G +PG A GA+G+ GL G G GPPG G G PG PAG +G GP Sbjct: 673 GQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPG---PAGHPGEQGQPGPE 729 Query: 802 WSTARSA----DGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQ 857 S G GP G PG KG G GLPG G G+DG G PG+PG+ G Sbjct: 730 GSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKR---GKM 786 Query: 858 GPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAG 916 G G G GE+G PG DG G+ GLPGPPG PG + G G G G Sbjct: 787 GMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLI--------------GDLGVLGPIG 832 Query: 917 FPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGF---RGPP 973 +PGP G KG +GS GE G G KGE+G PG S D G G KG++G PGF RG P Sbjct: 833 YPGPKGMKGLMGSVGEPGLKGDKGEQGVPG--VSGDPGFQG--DKGSQGLPGFPGARGKP 888 Query: 974 GPYGRPGYKGEIGFPGRP---------GRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGP 1024 GP G+ G KG IGFPG P G PG NG +G KG+PG L G RG GP G Sbjct: 889 GPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLP-GPRGQLGPEGD 947 Query: 1025 PGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPF-DFLQ 1083 GP GPPG P + +PG G PG G G KG G+ G PGP G+ F F+ Sbjct: 948 EGPMGPPGAPGLE-------GQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIG 1000 Query: 1084 LEAE--MKGEKGDR------GDAGQKGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIPG 1134 L E + GEKGDR G G KG G PG G G+ PGP GPPG RG PG+ G Sbjct: 1001 LVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRG 1060 Query: 1135 PKG-------------ESIRGQPGPPGPQGPPG-------------IGYEGRQGPPGPPG 1168 KG + RG GPPGPQG PG +G G G PGP G Sbjct: 1061 AKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSG 1120 Query: 1169 PPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1202 PPG PG PGP GP GP GPPG MG Sbjct: 1121 PPGTKGLPGE-------PGPQGPQGPIGPPGEMG 1147 Score = 205 bits (522), Expect = 2e-52 Identities = 165/471 (35%), Positives = 194/471 (41%), Gaps = 93/471 (19%) Query: 420 EGDDS----DGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTT---PPLAGGSSTE 472 EGD DG GD G D + + G + P PP VT P G E Sbjct: 1191 EGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGE 1250 Query: 473 DSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPG 532 R+ + LG +PG G TPG KG +G G G PG Sbjct: 1251 KGRTGAKGAKGYQGQLGEMGVPGDP------GPPGTPGP-------KGSRGSLGPTGAPG 1297 Query: 533 RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQT--------VPGPQGPPGPPGRDGTPGRD 584 R G G P L G G V PLGP GP + GP GPPG G G G Sbjct: 1298 RMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDR 1357 Query: 585 GEPGDPG---------------EDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV----GER 625 GEPGDPG + G+PG GP+G+PG G G +G KG G G R Sbjct: 1358 GEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRR 1417 Query: 626 GPPGPQGPPGPPGPSFRHDKLTFIDMEG----SGFGGDLEALRGPRGFPGPPGP------ 675 G G QG PGP G R +G G G + +G G PGP GP Sbjct: 1418 GVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQ-QGEQGDDGDPGPMGPAGKRGN 1476 Query: 676 PGVPGLPGEPGRFGVNS-SDVPGPAGLPG---------VPGREGPPG------------F 713 PGV GLPG G G S +PG G PG +PG +G PG F Sbjct: 1477 PGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGF 1536 Query: 714 PGLPG---PPGPPGR---------EGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGE 761 PG+ G P GPPG GPPG G++G +G G G G G G G+RG+ Sbjct: 1537 PGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGD 1596 Query: 762 SGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQ 812 GL G GP GP G PGPPGPPG + DD+ G+ W A P+ Sbjct: 1597 WGLQGPRGPPGPRGRPGPPGPPGGPIQLQQDDL-GAAFQTWMDTSGALRPE 1646 Score = 34.7 bits (78), Expect = 0.72 Identities = 48/182 (26%), Positives = 68/182 (37%), Gaps = 22/182 (12%) Query: 42 ATTIPEPQGPLPVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESP- 100 AT IP+ LP +P+A +T+ V ++ TAP S S L Q PTS P Sbjct: 361 ATKIPKS---LPTKPSAPSTSIVPIKSPHPTQKTAPSS-FTKSALPTQKQVPPTSRPVPA 416 Query: 101 ------DAPEENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGPLAL 154 + P + G+ + + +PT LAR E + P + Sbjct: 417 RVSRPAEKPIQRNPGMPRPPPPSTRPLPPTTSSSKKPIPT--LARTEAKITSHASKPASA 474 Query: 155 AGPSSTPQENGTTLWPSRGIPSSPGAHT-TEAGTLPAPTPSPPSLGRPWAPLTGPSVPPP 213 + P P + SSP + T P T PP+ G P T P+VP P Sbjct: 475 RTSTHKPP-------PFTALSSSPAPTPGSTRSTRPPATMVPPTSGTS-TPRTAPAVPTP 526 Query: 214 SS 215 S Sbjct: 527 GS 528 Score = 32.0 bits (71), Expect = 4.7 Identities = 56/237 (23%), Positives = 82/237 (34%), Gaps = 16/237 (6%) Query: 38 TSHAATTIPEPQGPLPVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSA 97 T+ +++ P P +P A T V P +G++ P TAP P P S G P + Sbjct: 485 TALSSSPAPTPGSTRSTRPPA---TMVPPTSGTSTPRTAPAVPTPGS--APTGSKKPIGS 539 Query: 98 ESPDAPEENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETP---VGPLAL 154 E+ + L K R V L +D S + + TP + P Sbjct: 540 EASKKAGPKSSPRKPVPLRPGKAARD-VPL-SDLTTRPSPRQPQPSQQTTPALVLAPAQF 597 Query: 155 AGPSSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPSL-GRPWAP-LTGPSVPP 212 S P +G +++ G P P PP L G P P GP PP Sbjct: 598 LSSSPRPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPP 657 Query: 213 P--SSERISEEVGLLQLLGDP--PPQQVTQTDDPDVGLAYVFGPDANSGQVARYHFP 265 + + G GDP P + D+GL + G G+ +P Sbjct: 658 GPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYP 714 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.141 0.451 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 109,700,050 Number of Sequences: 37866 Number of extensions: 10047328 Number of successful extensions: 399547 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 794 Number of HSP's successfully gapped in prelim test: 2120 Number of HSP's that attempted gapping in prelim test: 39510 Number of HSP's gapped (non-prelim): 52928 length of query: 1516 length of database: 18,247,518 effective HSP length: 115 effective length of query: 1401 effective length of database: 13,892,928 effective search space: 19463992128 effective search space used: 19463992128 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.