BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Homo sapiens] (1336 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Ho... 2848 0.0 gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Ho... 2776 0.0 gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho... 2775 0.0 gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens] 780 0.0 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 552 e-157 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 547 e-155 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 545 e-155 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 543 e-154 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 541 e-153 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 540 e-153 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 536 e-152 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 533 e-151 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 533 e-151 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 533 e-151 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 530 e-150 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 530 e-150 gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 528 e-149 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 527 e-149 gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 524 e-148 gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 523 e-148 gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 523 e-148 gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 514 e-145 gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 514 e-145 gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 512 e-144 gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 512 e-144 gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 512 e-144 gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 512 e-144 gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 504 e-142 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 504 e-142 gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 490 e-138 >gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Homo sapiens] Length = 1336 Score = 2848 bits (7382), Expect = 0.0 Identities = 1336/1336 (100%), Positives = 1336/1336 (100%) Query: 1 MAPRCPWPWPRRRRLLDVLAPLVLLLGVRAASAEPERISEEVGLLQLLGDPPPQQVTQTD 60 MAPRCPWPWPRRRRLLDVLAPLVLLLGVRAASAEPERISEEVGLLQLLGDPPPQQVTQTD Sbjct: 1 MAPRCPWPWPRRRRLLDVLAPLVLLLGVRAASAEPERISEEVGLLQLLGDPPPQQVTQTD 60 Query: 61 DPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVL 120 DPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVL Sbjct: 61 DPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVL 120 Query: 121 LGVKLSGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDC 180 LGVKLSGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDC Sbjct: 121 LGVKLSGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDC 180 Query: 181 EEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEE 240 EEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEE Sbjct: 181 EEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEE 240 Query: 241 GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 300 GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE Sbjct: 241 GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 300 Query: 301 EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSP 360 EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSP Sbjct: 301 EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSP 360 Query: 361 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG 420 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG Sbjct: 361 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG 420 Query: 421 PQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDL 480 PQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDL Sbjct: 421 PQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDL 480 Query: 481 EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP 540 EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP Sbjct: 481 EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP 540 Query: 541 GPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPP 600 GPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPP Sbjct: 541 GPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPP 600 Query: 601 GPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADG 660 GPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADG Sbjct: 601 GPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADG 660 Query: 661 VPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDG 720 VPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDG Sbjct: 661 VPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDG 720 Query: 721 SVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQ 780 SVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQ Sbjct: 721 SVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQ 780 Query: 781 KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPG 840 KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPG Sbjct: 781 KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPG 840 Query: 841 PPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFD 900 PPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFD Sbjct: 841 PPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFD 900 Query: 901 FLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESI 960 FLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESI Sbjct: 901 FLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESI 960 Query: 961 RGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGT 1020 RGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGT Sbjct: 961 RGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGT 1020 Query: 1021 MGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGT 1080 MGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGT Sbjct: 1021 MGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGT 1080 Query: 1081 DNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSY 1140 DNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSY Sbjct: 1081 DNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSY 1140 Query: 1141 VHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFR 1200 VHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFR Sbjct: 1141 VHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFR 1200 Query: 1201 AFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKD 1260 AFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKD Sbjct: 1201 AFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKD 1260 Query: 1261 VLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHH 1320 VLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHH Sbjct: 1261 VLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHH 1320 Query: 1321 AYIVLCIENSFMTASK 1336 AYIVLCIENSFMTASK Sbjct: 1321 AYIVLCIENSFMTASK 1336 >gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Homo sapiens] Length = 1516 Score = 2776 bits (7197), Expect = 0.0 Identities = 1304/1316 (99%), Positives = 1304/1316 (99%) Query: 21 PLVLLLGVRAASAEPERISEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVA 80 P L G ERISEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVA Sbjct: 201 PWAPLTGPSVPPPSSERISEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVA 260 Query: 81 RYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYT 140 RYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYT Sbjct: 261 RYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYT 320 Query: 141 EPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPG 200 EPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPG Sbjct: 321 EPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPG 380 Query: 201 AGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSGLGDARE 260 AGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSGLGDARE Sbjct: 381 AGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSGLGDARE 440 Query: 261 LLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVS 320 LLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVS Sbjct: 441 LLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVS 500 Query: 321 TWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP 380 TWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP Sbjct: 501 TWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP 560 Query: 381 ALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDP 440 ALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDP Sbjct: 561 ALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDP 620 Query: 441 GVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPG 500 GVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPG Sbjct: 621 GVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPG 680 Query: 501 LPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGE 560 LPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGE Sbjct: 681 LPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGE 740 Query: 561 AGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGP 620 AGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGP Sbjct: 741 AGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGP 800 Query: 621 FWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPK 680 FWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPK Sbjct: 801 FWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPK 860 Query: 681 GDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGP 740 GDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGP Sbjct: 861 GDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGP 920 Query: 741 AGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPG 800 AGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPG Sbjct: 921 AGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPG 980 Query: 801 YKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNV 860 YKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNV Sbjct: 981 YKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNV 1040 Query: 861 FAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQ 920 FAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQ Sbjct: 1041 FAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQ 1100 Query: 921 KGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGR 980 KGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGR Sbjct: 1101 KGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGR 1160 Query: 981 QGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQV 1040 QGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQV Sbjct: 1161 QGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQV 1220 Query: 1041 HEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPY 1100 HEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPY Sbjct: 1221 HEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPY 1280 Query: 1101 PRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSHRDFQ 1160 PRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSHRDFQ Sbjct: 1281 PRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSHRDFQ 1340 Query: 1161 PVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRA 1220 PVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRA Sbjct: 1341 PVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRA 1400 Query: 1221 AVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNG 1280 AVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNG Sbjct: 1401 AVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNG 1460 Query: 1281 RRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK 1336 RRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK Sbjct: 1461 RRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK 1516 Score = 33.1 bits (74), Expect = 1.8 Identities = 49/183 (26%), Positives = 60/183 (32%), Gaps = 31/183 (16%) Query: 381 ALQTVPGPQGP-PGPPGRDGT---------------PGRDGEPGDPGEDGKPGDTGPQGF 424 A T+P PQGP P P D T PG P + EDG+ T + Sbjct: 41 AATTIPEPQGPLPVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAES- 99 Query: 425 PGTPGD--VGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEA 482 P P + G + + G R P R + L G A Sbjct: 100 PDAPEENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGP------LA 153 Query: 483 LRGPRGFPGPPGPPGVP--GLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP 540 L GP P G P G+P PG + +P P P GR P L GP Sbjct: 154 LAGPSSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWAP----LTGPS 209 Query: 541 GPP 543 PP Sbjct: 210 VPP 212 >gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo sapiens] Length = 1751 Score = 2775 bits (7193), Expect = 0.0 Identities = 1301/1301 (100%), Positives = 1301/1301 (100%) Query: 36 ERISEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLL 95 ERISEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLL Sbjct: 451 ERISEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLL 510 Query: 96 FHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYTEPGAGQTHTAASFRL 155 FHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYTEPGAGQTHTAASFRL Sbjct: 511 FHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYTEPGAGQTHTAASFRL 570 Query: 156 PAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDK 215 PAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDK Sbjct: 571 PAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDK 630 Query: 216 FQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSGLGDARELLREETGAALKPRLP 275 FQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSGLGDARELLREETGAALKPRLP Sbjct: 631 FQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSGLGDARELLREETGAALKPRLP 690 Query: 276 APPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKE 335 APPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKE Sbjct: 691 APPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKE 750 Query: 336 GGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPP 395 GGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPP Sbjct: 751 GGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPP 810 Query: 396 GRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPG 455 GRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPG Sbjct: 811 GRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPG 870 Query: 456 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 515 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV Sbjct: 871 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 930 Query: 516 PGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGP 575 PGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGP Sbjct: 931 PGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGP 990 Query: 576 AGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPP 635 AGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPP Sbjct: 991 AGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPP 1050 Query: 636 GLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKD 695 GLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKD Sbjct: 1051 GLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKD 1110 Query: 696 GVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGS 755 GVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGS Sbjct: 1111 GVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGS 1170 Query: 756 PGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPG 815 PGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPG Sbjct: 1171 PGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPG 1230 Query: 816 MNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGN 875 MNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGN Sbjct: 1231 MNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGN 1290 Query: 876 QGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGS 935 QGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGS Sbjct: 1291 QGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGS 1350 Query: 936 SLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSF 995 SLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSF Sbjct: 1351 SLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSF 1410 Query: 996 PGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQE 1055 PGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQE Sbjct: 1411 PGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQE 1470 Query: 1056 ELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRA 1115 ELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRA Sbjct: 1471 ELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRA 1530 Query: 1116 DDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGG 1175 DDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGG Sbjct: 1531 DDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGG 1590 Query: 1176 MRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPS 1235 MRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPS Sbjct: 1591 MRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPS 1650 Query: 1236 WEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEA 1295 WEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEA Sbjct: 1651 WEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEA 1710 Query: 1296 PSATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK 1336 PSATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK Sbjct: 1711 PSATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK 1751 Score = 37.0 bits (84), Expect = 0.13 Identities = 74/301 (24%), Positives = 93/301 (30%), Gaps = 45/301 (14%) Query: 381 ALQTVPGPQGP-PGPPGRDGT---------------PGRDGEPGDPGEDGKPGDTGPQGF 424 A T+P PQGP P P D T PG P + EDG+ T + Sbjct: 41 AATTIPEPQGPLPVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAES- 99 Query: 425 PGTPGD--VGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEA 482 P P + G + + G R P R + L G A Sbjct: 100 PDAPEENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGP------LA 153 Query: 483 LRGPRGFPGPPGPPGVP--GLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP 540 L GP P G P G+P PG + +P P P GR P L GP Sbjct: 154 LAGPSSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWAP----LTGPS 209 Query: 541 GPPGREGPP------GRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGA---PGPA 591 PP G G GSL + + G + AP R + L P Sbjct: 210 VPPPSSGRASLSSLLGGAPPWGSLQDPDSQGLSPAAAAPSQQLQRPDVRLRTPLLHPLVM 269 Query: 592 GPPGPPGPPGPPGPGLPAGFDD-----MEGSGGPFWSTARSADGPQGPPGLPGLKGDPGV 646 G G P GLP + G + S ++ GP L DP Sbjct: 270 GSLGKHAAPSAFSSGLPGALSQVAVTTLTRDSGAWVSHVANSVGPGLANNSALLGADPEA 329 Query: 647 P 647 P Sbjct: 330 P 330 Score = 33.5 bits (75), Expect = 1.4 Identities = 85/361 (23%), Positives = 106/361 (29%), Gaps = 51/361 (14%) Query: 266 TGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVST---- 321 T A P P PP + L G T S + +A +GA+ L + + + Sbjct: 71 TEPATAPGSPEPP---SELLEDGQDTPTSAESPDAPEENIAGVGAEILNVAKGIRSFVQL 127 Query: 322 WDGSVRTPGGRVKEGGLKGQKGEPGVP-GPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP 380 W+ +V T E + + P GP AGP +P G P P P Sbjct: 128 WNDTVPT------ESLARAETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSPGAH 181 Query: 381 ALQTVPGPQGPPGPPGRDGTPGRDGEPGDP--GEDGKPGDTGPQGFPGTPGDVGPKGDKG 438 + P P PP G P P G P +G G P G Sbjct: 182 TTEAGTLPAPTPSPPSL-------GRPWAPLTGPSVPPPSSGRASLSSLLGGAPPWGSLQ 234 Query: 439 DPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGV 498 DP P P R + G G PG V Sbjct: 235 DPDSQGLSPAAAAPSQQLQRPDVRLRTPLLHPLVMGSLGKHAAPSAFSSGLPGALSQVAV 294 Query: 499 PGLPGEPGRF--GVNSSDVPGPAGLPGVPGR--EGPPGFPGLPGPPGPPGREGPPGRTGQ 554 L + G + V +S PG A + G E P G LP PP P G G Sbjct: 295 TTLTRDSGAWVSHVANSVGPGLANNSALLGADPEAPAG-RCLPLPPSLP----VCGHLG- 348 Query: 555 KGSLGEAGAPGH-KGSKGAPGPAGARGESGLAGA--------------PGPAGPPGPPGP 599 + P H G AGAR GL P G PP P Sbjct: 349 ---ISRFWLPNHLHHESGEQVRAGARAWGGLLQTHCHPFLAWFFCLLLVPPCGSVPPPAP 405 Query: 600 P 600 P Sbjct: 406 P 406 Score = 32.3 bits (72), Expect = 3.1 Identities = 74/299 (24%), Positives = 95/299 (31%), Gaps = 56/299 (18%) Query: 589 GPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGP-PGLPGLKGDPGVP 647 G P PG P PP L G D T SA+ P P + G+ G Sbjct: 69 GSTEPATAPGSPEPPSELLEDGQD-----------TPTSAESPDAPEENIAGV----GAE 113 Query: 648 GLPGAKG-----EVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGL 702 L AKG ++ D VP L E + + P G G P ++G Sbjct: 114 ILNVAKGIRSFVQLWNDTVP-TESLARAETLV-LETPVGPLALAGPSSTPQENGTTLWPS 171 Query: 703 PGPPGPPGPVVYVSEQDGSVLSVPGPE--GRPGFAGFPGPAGPKGNLGSKGERGSPGPKG 760 G P PG + +E P P GRP +A GP+ P S G G Sbjct: 172 RGIPSSPG--AHTTEAGTLPAPTPSPPSLGRP-WAPLTGPSVPP---PSSGRASLSSLLG 225 Query: 761 EKGEPGSIFSPDGGALGPAQKGAKGE--------------PGFRGPPGPYGRPGYKGEIG 806 GS+ PD L PA + P G G + P G Sbjct: 226 GAPPWGSLQDPDSQGLSPAAAAPSQQLQRPDVRLRTPLLHPLVMGSLGKHAAPSAFSS-G 284 Query: 807 FPGRPGRPGMNGLKGEKGE----------PGDASLGFGMRGMPGPPGPPGPPGPPGTPV 855 PG + + L + G PG A+ + P P P PP PV Sbjct: 285 LPGALSQVAVTTLTRDSGAWVSHVANSVGPGLANNSALLGADPEAPAGRCLPLPPSLPV 343 >gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens] Length = 1388 Score = 780 bits (2015), Expect = 0.0 Identities = 536/1474 (36%), Positives = 690/1474 (46%), Gaps = 254/1474 (17%) Query: 15 LLDVLAPLVLLLGVRAASAEPERISEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDA 74 LL V PL + R A+ + + L QL+G P P V+ AY FGP A Sbjct: 16 LLSVSTPLPAVTQTRGATETASQ--GHLDLTQLIGVPLPSSVSFVTGYGGFPAYSFGPGA 73 Query: 75 NSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQD 134 N G+ AR PS FFRDF++ ++P++ GVLFAITD+ Q ++ LG++LSGV+DGHQ Sbjct: 74 NVGRPARTLIPSTFFRDFAISVVVKPSSTRGGVLFAITDAFQKVIYLGLRLSGVEDGHQR 133 Query: 135 ISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRG 194 I L YTEPG+ + AA+F +P +W A+ V G V L V+CEE R+P RSS+ Sbjct: 134 IILYYTEPGSHVSQEAAAFSVPVMTHRWNRFAMIVQGEEVTLLVNCEEHSRIPFQRSSQA 193 Query: 195 LELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSG 254 L E AG+F+ AG ++F G + +L V DP+ C EE ASG++ SG Sbjct: 194 LAFESSAGIFMGNAGATGLERFTGSLQQLTVHPDPRTPEELCDPEESS----ASGET-SG 248 Query: 255 LGDA---RELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQ 311 L +A E+L T P+ P+ TPP + S E + T+ + Sbjct: 249 LQEADGVAEILEAVTYTQASPKEAKVEPINTPPTPSSPFEDMELSGEPVPEGTLETTNMS 308 Query: 312 TLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP 371 + S S + G + L+G G P +G + L Sbjct: 309 IIQHS--------SPKQGSGEILNDTLEGVHSVDGDPITDSGSGAGAFLDIAEEKNLAAT 360 Query: 372 VS-----PLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG--PQGF 424 + P+ AG A + P G P P PG E+ + Sbjct: 361 AAGLAEVPISTAGEA-EASSVPTGGPTLSMSTENPEEGVTPGPDNEERLAATAAGEAEAL 419 Query: 425 PGTPGDVGPKG--------DKGDPGVGERGPPGPQGPPG--PPGPSFRHDKLTFIDMEGS 474 PG+V G +GE GP + TF D E S Sbjct: 420 ASMPGEVEASGVAPGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEAS 479 Query: 475 GFGGD----LEALRGPR------------------------------GFPGPPGPPGVPG 500 G D L A P G P P GPP +P Sbjct: 480 GVPTDGLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPDGPP-LPL 538 Query: 501 LPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPG-----LPGPPGPPGREGPPGRTGQK 555 P R+ P G+ G+ GP G G LPGPP P G GP + Sbjct: 539 PTVAPERW-----ITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAE 593 Query: 556 GSLGEAGAPGHKGS----------KGAPGPAGARGESGLAGAPG------PAGPPGPPGP 599 GS G+ GS +G PGP G G G+ G PG P G PG GP Sbjct: 594 GSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGP 653 Query: 600 PGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGAD 659 G PGP P G ++G+ G + G +GP G G KGDPG GLPG G+ G Sbjct: 654 AGEPGPPGPEGQPGVDGATG--LPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQA 711 Query: 660 GVPGFPGLPGREGIAGPQGP----------------------------------KGDRGS 685 G PG G PG G GP GP KG++G Sbjct: 712 GPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGD 771 Query: 686 RGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSV-------------LSVPGPEGRP 732 RG KG+ G DG G PGP GPPG + +S ++ + PGP+G P Sbjct: 772 RGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLP 831 Query: 733 GFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQK--GAKGEPGFR 790 G GFPGP GPKG+ G G G G +GEKGEPG+I + D P ++ G KGEPG Sbjct: 832 GLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDI----PLERLMGKKGEPGMH 887 Query: 791 GPPGPYGR---PGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGP 847 G PGP G PG+KGE G PGRPGRPG+NGLKG KG+PG M+G PG PGPPGP Sbjct: 888 GAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVI-----MQGPPGLPGPPGP 942 Query: 848 PGPPGTPVYDSNVF------------AESSRPGPP---------GLPGNQGPPGPKGAKG 886 PGPPG + +++ PG P G G+ G PG KG KG Sbjct: 943 PGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKG 1002 Query: 887 EVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPG--GGGFFGSSLPGPPGPP 944 + G GPPG P D L + KG+ GD G KGE+GE G G F S PG PG P Sbjct: 1003 DQGAQGPPGP-PLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNP 1061 Query: 945 GPRGYPG--IPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQT 1002 GP G G + GP+G PG PG GPPG G G GPPGPPGPPGPP+ G Sbjct: 1062 GPAGQKGETVVGPQGP-----PGAPGLPGPPGFGRPGDPGPPGPPGPPGPPAILGA---A 1113 Query: 1003 ISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQ 1062 +++PGPPGPPG PG PG+ V ++ ML + H V EG I++ + E ++RV+ Sbjct: 1114 VALPGPPGPPGQPGLPGSRNL---VTAFSNMDDMLQKAHLVIEGTFIYLRDSTEFFIRVR 1170 Query: 1063 NGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASP 1122 +G++K+QL P+P A PP L SNP+ Sbjct: 1171 DGWKKLQLGELIPIP--------ADSPPPPAL-SSNPHQL-------------------- 1201 Query: 1123 PRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGA 1182 LP P P A + +P LHL ALN P SG +R A Sbjct: 1202 --LPPPNPISSANYE----------------------KPALHLAALNMPFSGDIR----A 1233 Query: 1183 DFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSG 1242 DFQCF+QARA GL T+RAFLSS LQDL +IVR+A+R ++PIVNLK ++LF +W+++FSG Sbjct: 1234 DFQCFKQARAAGLLSTYRAFLSSHLQDLSTIVRKAERYSLPIVNLKGQVLFNNWDSIFSG 1293 Query: 1243 SEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQA 1302 G I+SFDG+D++ P+WPQK +WHGS P+G RL ++YCE WRT + TG A Sbjct: 1294 HGGQFNMHIPIYSFDGRDIMTDPSWPQKVIWHGSSPHGVRLVDNYCEAWRTADTAVTGLA 1353 Query: 1303 SSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK 1336 S L G++L Q A SC + IVLCIENSFMT ++ Sbjct: 1354 SPLSTGKILDQKAYSCANRLIVLCIENSFMTDAR 1387 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 552 bits (1422), Expect = e-157 Identities = 392/966 (40%), Positives = 433/966 (44%), Gaps = 216/966 (22%) Query: 246 GASGDSGSG--------------LGDARELLREETGAALKPRLPAPPPVTTPPLAGGSST 291 G GD+GS L AR LR G P P PP +GG Sbjct: 527 GGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGP---VGPPGSGGLKG 583 Query: 292 EDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--------GLKGQKG 343 E + G PG + DG+ PG +G GL G+KG Sbjct: 584 EPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKG 643 Query: 344 EPGVPGPPGRAGPPGS---------------PCLPGPPGLPCPVSPLGPAGP----ALQT 384 G PGP G GPPG P PGP GL P P GP GP + Sbjct: 644 HRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDG 703 Query: 385 VPGP------QGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKG 438 PGP QG PGPPG+ G PG G PG G G PG+ GP G PG PG G G G Sbjct: 704 QPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPG 763 Query: 439 DPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS----------GFGGDLE 481 PG G +GPPGPQGP G PGP ++G+ GF GD+ Sbjct: 764 HPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDM- 822 Query: 482 ALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP----------GPAGLPGVPGREGP- 530 ++G RG GPPGP G G G GR G N P G GLPG PGR+GP Sbjct: 823 GIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPK 882 Query: 531 -----PGFPGL---------PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPA 576 PGFPG PG PGP G+ GP G G++G G G PG KG+ G GPA Sbjct: 883 GSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPA 942 Query: 577 GARGESGLAGAPGPAGPPGPPGPPGPPG----PGLP-----AGFDDMEGSGGPFWSTA-- 625 G GE G G GP G PGP GPPGPPG PG P GF G GP Sbjct: 943 GPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQ 1002 Query: 626 -----------RSADGPQGPP---GLPGL------KGDPGVPGLPGAKGEVGADGVPGFP 665 R GP GPP GLPGL KGDPG GLPG G G G PG Sbjct: 1003 GPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDR 1062 Query: 666 GLP------GREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQ 718 GLP G +G GP GP G GS GE+G G G +G PG PGP GPPGP E+ Sbjct: 1063 GLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGP---AGEK 1119 Query: 719 DGSVLSVP-GPEGRPGF---AGFPGPAGP---------KGNLGSKGERGSPGPKGEKGEP 765 P GP GR G G PGPAGP KG +G G++GS G KGE+G P Sbjct: 1120 GAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPP 1179 Query: 766 GSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGL---KGE 822 G P G P GA GEPG RG G +G+ G +G GFPG PG G+ GL GE Sbjct: 1180 GPT-GPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGE 1238 Query: 823 KGEPGDASLGFGMRGMPGPPGPPGPPGPPGTP--------VYDSNVFAESSRP---GPPG 871 KGE GD G G PGPPGP GP G PG + + E P G PG Sbjct: 1239 KGETGDV----GQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPG 1294 Query: 872 LPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGG 931 LPG GPPGPKG +GE G GP G G G +G G G +G PG G Sbjct: 1295 LPGEGGPPGPKGERGEKGESGPSG------------AAGPPGPKGPPGDDGPKGSPGPVG 1342 Query: 932 FFGSSLPGPPGPPGPRGYPGIPGPKGE----SIRGQPGP---PGPQGPPG-------IGY 977 F G PGPPG PGP G G PG KG+ G PGP PGP GPPG G Sbjct: 1343 FPGD--PGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGP 1400 Query: 978 EGRQ------------GPP---GPPGPPGPPSFPGPHRQTISVPGP------PGPPGPPG 1016 EGRQ GPP GP GP G P PGP +PGP PG PGP G Sbjct: 1401 EGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLR-GIPGPVGEQGLPGSPGPDG 1459 Query: 1017 PPGTMG 1022 PPG MG Sbjct: 1460 PPGPMG 1465 Score = 529 bits (1363), Expect = e-150 Identities = 375/945 (39%), Positives = 425/945 (44%), Gaps = 164/945 (17%) Query: 193 RGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSD-GASGDS 251 RGL EPG + G P GV D Q P + +G+ G G+ Sbjct: 672 RGLPGEPGPRGLLGPKGPPGPPGPPGVTG-----MDGQPGPKGNVGPQGEPGPPGQQGNP 726 Query: 252 GS-GLGDARELLRE--ETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASL 308 G+ GL + + E G KP LP P PP G ++ E Q Sbjct: 727 GAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPP---GHPGKEGPPGEKGGQGPPGPQ 783 Query: 309 GAQTLPGSDSVSTWDGSVRTPGGRVKEG-----------GLKGQKGEPGVPGPPGRAGPP 357 G PG V DG G + ++G G+KG +GE G PGP G GP Sbjct: 784 GPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPE 843 Query: 358 GSPCLPGPPGLPCPVSPLGPAG----PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGED 413 G GP G P P+ P G G P L PG QGP G G G PG +GE G G Sbjct: 844 GPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTP 903 Query: 414 GKPGDTGPQGFPGTPGDVGPKGDKGDPGV-------------GERGPPGPQGPPG----- 455 GKPG G +G G G+ GP+G G PG GERGP GPQGP G Sbjct: 904 GKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPK 963 Query: 456 -PPGPSFRHDKLTFIDMEG-SGFGGDL-----------------EALRGPRGFPGPPGPP 496 PPGP + G +GF G G RG PGPPGPP Sbjct: 964 GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPP 1023 Query: 497 GVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKG 556 G GLPG G+ G PGPAGLPG ++GPPG G PG G PG P G G KG Sbjct: 1024 GEQGLPGLAGKEGTKGD--PGPAGLPG---KDGPPGLRGFPGDRGLPG---PVGALGLKG 1075 Query: 557 SLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG---PGLPAGFDD 613 + G G PG GS G GPAGA G G+ G PGP GPPGP G G PG P PAG D Sbjct: 1076 NEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1135 Query: 614 MEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPG------L 667 ++G G GP GPPG G KG+ G PG G+KG+ G G PG G Sbjct: 1136 LQGPVG-----LPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQ 1190 Query: 668 PGREGIAGPQGPKGDRGSRGEKGDPGKDG-------VGQPGLPGPPGPPGPVVYVSEQDG 720 PG G G GP+G +G G+KGD G G VG GLPGPPG G V + Sbjct: 1191 PGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGP 1250 Query: 721 SVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGP-- 778 PGP G G G GP GP G +G+ G G G GE GEPG +GG GP Sbjct: 1251 P--GPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPG--LPGEGGPPGPKG 1306 Query: 779 --AQKGAKGEPGFRGPPGPYGRPG------YKGEIGFPGRPGRPGMNGLKGEKGEPGDAS 830 +KG G G GPPGP G PG G +GFPG PG PG G G+ G PGD Sbjct: 1307 ERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKG 1366 Query: 831 LGF--GMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEV 888 G G PGP G PGP GPPG + GPPG G +G G KGAKGE Sbjct: 1367 DDGEPGQTGSPGPTGEPGPSGPPG-------------KRGPPGPAGPEGRQGEKGAKGEA 1413 Query: 889 GPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRG 948 G GPPG+ Q G G RG G GE+G PG PGP GPPGP G Sbjct: 1414 GLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGS--------PGPDGPPGPMG 1465 Query: 949 YPGIPGPKGES-------------------------IRGQPGPPGPQGPPGI-GYEGRQG 982 PG+PG KG+S RG PGP G GP G G G G Sbjct: 1466 PPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSG 1525 Query: 983 PPGPPGPPGPPSFPGPH--RQTISVPGP------PGPPGPPGPPG 1019 P GPPGPPG P PGP + + GP PGPPGPPGPPG Sbjct: 1526 PIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPG 1570 Score = 512 bits (1319), Expect = e-145 Identities = 327/744 (43%), Positives = 373/744 (50%), Gaps = 94/744 (12%) Query: 307 SLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSPCLPG 364 S+G PG++ G+ PG R + G G +G++G G+ G PG G G G Sbjct: 884 SIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAG 943 Query: 365 PPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGF 424 PPG P P GP G PGP+GPPGPPG+DG PG PG GE G G TGP Sbjct: 944 PPGERGPNGPQGPTG-----FPGPKGPPGPPGKDGLPGH---PGQRGETGFQGKTGP--- 992 Query: 425 PGTPGDVGPKGDKGDPG-VGERGPPGPQGPPGPPG-PSFRHDKLTFIDMEGSGFGGD--- 479 PG PG VGP+G G+ G +GERG PGP GPPG G P + T D +G G Sbjct: 993 PGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGP 1052 Query: 480 --LEALRGPRGFPGP---------PGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGRE 528 L G RG PGP GPPG PG G PG G + GP G+PG PG + Sbjct: 1053 PGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERG--PAGAAGPIGIPGRPGPQ 1110 Query: 529 GPPG------FPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA---PGPAGAR 579 GPPG PG GP GP GR+G G G G G G PG G KG PG G++ Sbjct: 1111 GPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSK 1170 Query: 580 GESGLAGAPGPAGPPGPPGPPGP------PGPGLPAGFDDMEGSGGPFWSTARSADGPQG 633 G+ G G PGP GP GP G PGP PGP G +G GP R GP G Sbjct: 1171 GDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGP-----RGFPGPPG 1225 Query: 634 PPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKG---DRGSRGEKG 690 P GL GL G PG G G G++G G PG G G G GPQGP G + G+ GEKG Sbjct: 1226 PVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKG 1285 Query: 691 DPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSK 750 +PG+ G+PGLPG GPPGP G +G G +G GP GPKG G Sbjct: 1286 EPGE--AGEPGLPGEGGPPGPK-----------GERGEKGESGPSGAAGPPGPKGPPGDD 1332 Query: 751 GERGSPGPKGEKGEPGSIFSPD--GGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFP 808 G +GSPGP G G+PG P G P KG GEPG G PGP G PG G G Sbjct: 1333 GPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKR 1392 Query: 809 GRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPG 868 G PG G G +GEKG G+A G+ G PG GP GP G PG P D PG Sbjct: 1393 GPPGPAGPEGRQGEKGAKGEA----GLEGPPGKTGPIGPQGAPGKPGPDGL----RGIPG 1444 Query: 869 PPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPG 928 P G G G PGP G G +GPPG PG L+ ++ KGEKG G G G GE G Sbjct: 1445 PVGEQGLPGSPGPDGPPGPMGPPGLPG------LKGDSGPKGEKGHPGLIGLIGPPGEQG 1498 Query: 929 GGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI-GYEGRQGPPGP- 986 G G LPGP G GP+G GI GP G G PGPPG GPPG G +G GP GP Sbjct: 1499 EKGDRG--LPGPQGSSGPKGEQGITGPSGPI--GPPGPPGLPGPPGPKGAKGSSGPTGPK 1554 Query: 987 -----PGPPGPPSFPGPHRQTISV 1005 PGPPGPP PG Q + + Sbjct: 1555 GEAGHPGPPGPPGPPGEVIQPLPI 1578 Score = 495 bits (1275), Expect = e-139 Identities = 413/1202 (34%), Positives = 498/1202 (41%), Gaps = 258/1202 (21%) Query: 18 VLAPLVLLLGVRAASAEPERISEEVGLLQLLG-DPPPQQVTQTDD----------PDVGL 66 +L PL+LLL + P R ++ LL++L P +T+T PDV Sbjct: 19 LLPPLLLLL---LWAPPPSRAAQPADLLKVLDFHNLPDGITKTTGFCATRRSSKGPDV-- 73 Query: 67 AYVFGPDANSGQVARYHFP-SLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKL 125 AY DA + +P S F DFS+L ++ L +I + G++ Sbjct: 74 AYRVTKDAQLSAPTKQLYPASAFPEDFSILTTVKAKKGSQAFLVSIYNEQ------GIQQ 127 Query: 126 SGVQDGHQDISLLYTEPGAGQTHTAASFR-LPAFVGQWTHLALSVAGGFVALYVDCEEFQ 184 G++ G + L G FR + G+W +ALSV V L +DC++ Sbjct: 128 IGLELGRSPVFLYEDHTGKPGPEDYPLFRGINLSDGKWHRIALSVHKKNVTLILDCKKKT 187 Query: 185 RMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDS 244 L RS + G+ V D + F+G I +L D + + +C + D Sbjct: 188 TKFLDRSDH--PMIDINGIIVFGTRILDEEVFEGDIQQLLFVSDHRAAYDYC-EHYSPDC 244 Query: 245 DGASGDS--------------GSGLG-----------DARELLREETGA-----ALKPRL 274 D A D+ G G G D +L +E T + A K Sbjct: 245 DTAVPDTPQSQDPNPDEYYTEGDGEGETYYYEYPYYEDPEDLGKEPTPSKKPVEAAKETT 304 Query: 275 PAPPPVTTPPL---------AGGSSTED-------------------------SRSEEVE 300 P +T P G ED EE Sbjct: 305 EVPEELTPTPTEAAPMPETSEGAGKEEDVGIGDYDYVPSEDYYTPSPYDDLTYGEGEENP 364 Query: 301 EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGE---------------- 344 +Q T GA+ + S PG + L+G+ E Sbjct: 365 DQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADD--LEGEFTEETIRNLDENYYDPYYD 422 Query: 345 ---------PGVPGP-----PGRAGPPGSPCLPGPPGLPCP----VSPLGPAGPA-LQTV 385 PG+P G GP G G P + P P GP GPA L Sbjct: 423 PTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGP 482 Query: 386 PGPQGPP---------GPPGRDGTPGRDGEPGDPG-------EDGKPGD----------- 418 PG GP GPPGR G PG DG PG PG G GD Sbjct: 483 PGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQ 542 Query: 419 ------------------TGPQGFPGTPGDVGPKGD---KGDPG-VGERGPPGPQGPPGP 456 GP G G PG VGP G KG+PG VG +GP G QGPPGP Sbjct: 543 ESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGP 602 Query: 457 PGPSFRHDKLTFIDMEG----------SGFGG--DLEALRGPRGFPGPPGPPGVPGLPGE 504 G R + G GF G L +G RG PGP GPPG PG GE Sbjct: 603 AGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGE 662 Query: 505 PGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAP 564 G G GP GLPG PG G G G PGPPGPPG G G+ G KG++G G P Sbjct: 663 RGDDG-----EVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEP 717 Query: 565 GHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWST 624 G G +G PG G G G G PG GP G PG PG PG P G EG G Sbjct: 718 GPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGE--KG 775 Query: 625 ARSADGPQGPPGLP---GLKGDPGVPGLPGAKGEVGADGVPGFP---GLPGREGIAGPQG 678 + GPQGP G P G+KG G+ GL G KGE G DG PGF G+ G G GP G Sbjct: 776 GQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPG 835 Query: 679 PKGDRGSRGEK------GDPG-------KDGVGQPGLPGPPGPPGPVVYVSEQDGSV--L 723 P+G+ G G K GDPG K +G PGLPG PG GP GS+ Sbjct: 836 PRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGP-------KGSIGFP 888 Query: 724 SVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGA 783 PG G G G PG GP+G G G RG GP+G G+PG P G + G G Sbjct: 889 GFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPG----PKGNSGG---DGP 941 Query: 784 KGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPG 843 G PG RGP GP G G+ G G PG PG+ G+ G G++GE G +G GPPG Sbjct: 942 AGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGET-------GFQGKTGPPG 994 Query: 844 PPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQ 903 PPG GP G P ++ E PGPPG PG QG PG G +G G PGP G Sbjct: 995 PPGVVGPQG-PTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAG-------- 1045 Query: 904 LEAEMKGEKGDRGDAGQKGERGEPGGGGFFG-SSLPGPPGPPGPRGYPGIPGPKGES-IR 961 + G+ G G G G+RG PG G G GPPGPPGP G PG GP G + Sbjct: 1046 ----LPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPI 1101 Query: 962 GQPGPPGPQGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGT 1020 G PG PGPQGPPG G +G G GP GP G GP + +PGP GP GPPG G Sbjct: 1102 GIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGP----VGLPGPAGPVGPPGEDGD 1157 Query: 1021 MG 1022 G Sbjct: 1158 KG 1159 Score = 447 bits (1151), Expect = e-125 Identities = 284/636 (44%), Positives = 314/636 (49%), Gaps = 64/636 (10%) Query: 263 REETGAALKPRLPAPPPVTTP---------------PLAGGSSTEDSRSEEVEEQTTVAS 307 R ETG K P PP V P P G E ++ T Sbjct: 981 RGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGD 1040 Query: 308 LGAQTLPGSDSVSTWDGSVRTPG--GRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGP 365 G LPG D G G G V GLKG +G PG PGP G G G GP Sbjct: 1041 PGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGP 1100 Query: 366 PGLPCPVSPLGPAGPALQT-VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGF 424 G+P P GP GPA + PG +GP GP GRDG G G PG G G PG+ G +G Sbjct: 1101 IGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGE 1160 Query: 425 PGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS-GFGGDLEAL 483 G PG G KGDKG+ G GP GPQGP G PGPS + +G G GD Sbjct: 1161 IGEPGQKGSKGDKGEQG--PPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGD---- 1214 Query: 484 RGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP 543 GPRGFPGPPGP G+ GLPG PG G + DV G G PG PG GP G PG GP GPP Sbjct: 1215 EGPRGFPGPPGPVGLQGLPGPPGEKG-ETGDV-GQMGPPGPPGPRGPSGAPGADGPQGPP 1272 Query: 544 GREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPP 603 G G PG G+KG GEAG PG G G PGP G RGE G +G G AGPPGP GPPG Sbjct: 1273 GGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDD 1332 Query: 604 GPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPG 663 GP G G GP + G GPPG G G+PG G PG GE G G PG Sbjct: 1333 GPKGSPGPVGFPGDPGPPGEPGPA--GQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPG 1390 Query: 664 FPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSV 722 G PG G G QG KG +G G +G PGK G +G G PG PGP G + Sbjct: 1391 KRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDG-----------L 1439 Query: 723 LSVPGPEGRPGFAGFPGPAGPKGNLGS---KGERGSPGPKGEKGEPGSIFSPDGGALGPA 779 +PGP G G G PGP GP G +G G +G GPKGEKG PG I G +GP Sbjct: 1440 RGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLI-----GLIGP- 1493 Query: 780 QKGAKGEPGFRGPPGPYGRPGYKGE---------IGFPGRPGRPGMNGLKGEKGEPGDAS 830 G +GE G RG PGP G G KGE IG PG PG PG G KG KG G Sbjct: 1494 -PGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPT- 1551 Query: 831 LGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR 866 G +G G PGPPGPPGPPG + + A +R Sbjct: 1552 ---GPKGEAGHPGPPGPPGPPGEVIQPLPIQASRTR 1584 Score = 52.4 bits (124), Expect = 3e-06 Identities = 57/209 (27%), Positives = 73/209 (34%), Gaps = 32/209 (15%) Query: 845 PGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQL 904 P P P ++ E P P + P P+ ++G G G +D++ Sbjct: 290 PTPSKKPVEAAKETTEVPEELTPTP-----TEAAPMPETSEG-AGKEEDVGIGDYDYVPS 343 Query: 905 EAEMKGEKGDRGDAGQKGERGE----PGGGGFFGSSLPGP-----PGPPGPRGYPGIPGP 955 E D G+ E + PG G +S P PP G + G Sbjct: 344 EDYYTPSPYDDLTYGEGEENPDQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGE 403 Query: 956 -KGESIRG--------------QPGPPGPQGPPGIG--YEGRQGPPGPPGPPGPPSFPGP 998 E+IR P GP P YEG GP G G G P+ P Sbjct: 404 FTEETIRNLDENYYDPYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEP 463 Query: 999 HRQTISVPGPPGPPGPPGPPGTMGASSGV 1027 PGP GP G PGPPGTMG + V Sbjct: 464 GMLIEGPPGPEGPAGLPGPPGTMGPTGQV 492 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 547 bits (1410), Expect = e-155 Identities = 354/832 (42%), Positives = 392/832 (47%), Gaps = 129/832 (15%) Query: 275 PAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVK 334 P P P G + E ++ E G +PG DG +PG Sbjct: 416 PGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGA 475 Query: 335 EG--GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG-PALQTVPGPQGP 391 G G G++G PG GP G G PG G G P P P G AG P VPG G Sbjct: 476 NGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGM 535 Query: 392 PGPPGRDGTPGRDGEPGDPGEDGK------PGDTGPQGFPGTPGDVGPKGDKGDPGV-GE 444 G PG G PG DG+PG PG G+ PG +GP+G PG G GPKG+ G PG GE Sbjct: 536 RGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGE 595 Query: 445 RGPPG---PQGPPG---------PPGPSFRHDKLTFIDMEGSGFGGDL-----EALRGPR 487 RG PG PQGPPG PPGP+ G GGD +G + Sbjct: 596 RGGPGGPGPQGPPGKNGETGPQGPPGPT--------------GPGGDKGDTGPPGPQGLQ 641 Query: 488 GFPGPPGPPGVPGLPGEPGRFG-VNSSDVPGPAGLPGVPGREGPPGFPGLPG-------- 538 G PG GPPG G PGEPG G + PG G G PG GPPG G PG Sbjct: 642 GLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPP 701 Query: 539 ----------PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAP 588 PPGPPG G PG G G G G+PG KG KG PG GA G G G Sbjct: 702 GPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPR 761 Query: 589 GPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTA-RSADGPQGP---PGLPGLKGDP 644 GP GP GPPGP G PG G + G GP S R GP GP PG PG G+P Sbjct: 762 GPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEP 821 Query: 645 GVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGV-GQPGLP 703 G G GA GE G G PG G PG G AGP GP+G +G RG G PG G G GLP Sbjct: 822 GGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLP 881 Query: 704 GPPG------PPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPG 757 GPPG PPGP + DG PGP G G G PG +GPKG+ G GE+GSPG Sbjct: 882 GPPGSNGNPGPPGPSGSPGK-DGP----PGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPG 936 Query: 758 PKGEKGEPG-----------SIFSPDG-----GALGP-------AQKGAKGEPGFRGPPG 794 +G G PG + P G G+ GP + GA G G RGPPG Sbjct: 937 AQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPG 996 Query: 795 PYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTP 854 P G PG G G PGR G PG +GL G G PG G G PG PG PG PGPPG P Sbjct: 997 PQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKG-DRGENGSPGAPGAPGHPGPPG-P 1054 Query: 855 VYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGD 914 V + + GP G G PGP G++G GP GP G KGE G+ Sbjct: 1055 VGPAGKSGDRGESGPAG---PAGAPGPAGSRGAPGPQGPRGD------------KGETGE 1099 Query: 915 RGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG 974 RG AG KG RG PG G PG PGP G +G G PGP G GP GP GPPG Sbjct: 1100 RGAAGIKGHRGFPGNPG-----APGSPGPAGQQGAIGSPGPAGPR-----GPVGPSGPPG 1149 Query: 975 IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSG 1026 +G G PGP GPPGP G R + PG PG PGPPGPPG G G Sbjct: 1150 --KDGTSGHPGPIGPPGPRGNRG-ERGSEGSPGHPGQPGPPGPPGAPGPCCG 1198 Score = 528 bits (1359), Expect = e-149 Identities = 350/882 (39%), Positives = 396/882 (44%), Gaps = 152/882 (17%) Query: 246 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 305 G SG +G R E G P + P + P G D R+ E E Sbjct: 222 GPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAP 281 Query: 306 ASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG-----------GLKGQKGEPGVPGPPGRA 354 G LPG + G PG R + G G +G G+PG PGPPG A Sbjct: 282 GLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTA 341 Query: 355 GPPGSPCL---------------------------------PGPPGL---PCPVSPLGPA 378 G PGSP PGPPG+ P +GPA Sbjct: 342 GFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPA 401 Query: 379 G-PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQG------FPGTPGDV 431 G P + G +GPPGP G +G PG G G+PG++G G+ GP+G PG PG Sbjct: 402 GIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAK 461 Query: 432 GPKGDKGDPG----------VGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLE 481 G G G PG GERG PG +GP GP G + Sbjct: 462 GEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNG---------------------IP 500 Query: 482 ALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPG 541 +GP G G PGP G G GEPGR GV PG G+PG PG G G PG PG G Sbjct: 501 GEKGPAGERGAPGPAGPRGAAGEPGRDGVPGG--PGMRGMPGSPGGPGSDGKPGPPGSQG 558 Query: 542 PPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPG 601 GR GPPG +G +G G G PG KG+ GAPG G RG G G GP G G GP G Sbjct: 559 ESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQG 618 Query: 602 PPGPGLPA------------GFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGL 649 PPGP P G + G+GGP G G PG PG KGD G PG Sbjct: 619 PPGPTGPGGDKGDTGPPGPQGLQGLPGTGGP--------PGENGKPGEPGPKGDAGAPGA 670 Query: 650 PGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGP 708 PG KG+ GA G G PGL G G+ G GP G G +G G PG G G PGL G PG Sbjct: 671 PGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGE 730 Query: 709 PGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSI 768 G + + PG G G G GP GP G +G G G PG KGE G PG Sbjct: 731 RGGLGSPGPKGDK--GEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGL- 787 Query: 769 FSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGD 828 G GP +G+ GE G GPPGP G PG G+ G PG G G G KGE G PG Sbjct: 788 ----PGIAGP--RGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGV 841 Query: 829 ASL--GFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKG 886 A G G G PGP G G G PG P + PGPPG GN GPPGP G+ G Sbjct: 842 AGPPGGSGPAGPPGPQGVKGERGSPGGP-GAAGFPGARGLPGPPGSNGNPGPPGPSGSPG 900 Query: 887 EVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGS----------- 935 + GPPGP G G G +GDAGQ GE+G PG G G+ Sbjct: 901 KDGPPGPAGNTG------APGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITG 954 Query: 936 --SLPGPPGPPGPRGYPGIPGPKGES-------IRGQPGPPGPQGPPGI----GYEGRQG 982 L GPPG PGPRG PG G KGES + G+ GPPGPQG PG+ G GR G Sbjct: 955 ARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDG 1014 Query: 983 PPGPPGPPGPPSFPG--PHRQTISVPGPPGPPGPPGPPGTMG 1022 PG G PG PG R PG PG PG PGPPG +G Sbjct: 1015 NPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVG 1056 Score = 527 bits (1358), Expect = e-149 Identities = 336/797 (42%), Positives = 376/797 (47%), Gaps = 133/797 (16%) Query: 327 RTPGGRVKEGGLKGQKGEPGVPG---PPGRAGPPGSPCLPGPPGL--PCPVSPL------ 375 R P G+ +G KG G PG+PG PG G PGSP PGPPG+ CP P Sbjct: 97 RPPNGQGPQGP-KGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQY 155 Query: 376 -------GPAGPALQTVPGPQGPP---GPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFP 425 G A L PGP GPP GPPG G PG G PG G G+PG GP G P Sbjct: 156 DSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPP 215 Query: 426 GTPGDVGPKGDKGDPG-VGERGPPGPQGPPGPPGPSFRHDKLTFIDMEG-SGFGG----- 478 G PG +GP G G G G G PG +G PGPPG F M+G GF G Sbjct: 216 GPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEK 275 Query: 479 ---------DLEALRGPRGFPGPPGPPGVP---GLPGEPGRFGVNSSD-VPGPAGLPGVP 525 L G G PGP GP G P G PG PG G +D G G PG P Sbjct: 276 GETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPP 335 Query: 526 GREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLA 585 G G GFPG PG G G G PG G G GE G GH G++G PGP G G G Sbjct: 336 GPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGK 395 Query: 586 GAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPG 645 G GPAG PG PG G GP PAG + G G + +G +G PG G +G+ G Sbjct: 396 GEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGK--NGAKGEPGPRGERGEAG 453 Query: 646 VPGLPGAKGEVGADGVPGFP------------------------GLPGREGIAGPQGPKG 681 +PG+PGAKGE G DG PG P G+PG +G AG +G G Sbjct: 454 IPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPG 513 Query: 682 DRGSRGEKGDPGKDGV----GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGF 737 G RG G+PG+DGV G G+PG PG PG DG PGP G G +G Sbjct: 514 PAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPG-------SDGK----PGPPGSQGESGR 562 Query: 738 PGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYG 797 PGP GP G G G G PGPKG G PG GG GP +G G+ G GP GP G Sbjct: 563 PGPPGPSGPRGQPGVMGFPGPKGNDGAPGK-NGERGGPGGPGPQGPPGKNGETGPQGPPG 621 Query: 798 RPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYD 857 G G+ G G PG G+ GL G G PG+ G PG PGP G G PG P Sbjct: 622 PTGPGGDKGDTGPPGPQGLQGLPGTGGPPGE-------NGKPGEPGPKGDAGAPGAPGGK 674 Query: 858 SNVFAESSR-----PGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEK 912 + A R G PGL G GPPGP+G KG GPPGPPG LQ M GE+ Sbjct: 675 GDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQ---GMPGER 731 Query: 913 GDRGDAGQKGERGEPGGGGFFG-------SSLPGPPGPPGPR------------GYPGIP 953 G G G KG++GEPGG G G GP GPPGP G PGI Sbjct: 732 GGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIA 791 Query: 954 GPKGE-SIRGQPGPPGPQGPPGI-------GYEGRQGPPGPPGPPGPPSFPGPHRQTISV 1005 GP+G RG+ GPPGP G PG G +G +G PG G GPP GP Sbjct: 792 GPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGP------- 844 Query: 1006 PGPPGPPGPPGPPGTMG 1022 PG GP GPPGP G G Sbjct: 845 PGGSGPAGPPGPQGVKG 861 Score = 469 bits (1206), Expect = e-131 Identities = 312/728 (42%), Positives = 335/728 (46%), Gaps = 137/728 (18%) Query: 370 CPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPG 429 CP P P P GPQGP G PG G PGR+G+PG PG+ PG+PG Sbjct: 88 CPQPPTAPTRPP--NGQGPQGPKGDPGPPGIPGRNGDPGIPGQ------------PGSPG 133 Query: 430 DVGPKG----------------DKGD--PGV---GERGPPGPQGPPGPPGPSFRHDKLTF 468 GP G D D GV G G PGP GPPGPPGP Sbjct: 134 SPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPP-------- 185 Query: 469 IDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP-------GPAGL 521 G G PG PG PG G PGEPG+ G + P GPAG Sbjct: 186 ----------------GTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGK 229 Query: 522 PGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGE 581 G GR G PG GLPGPPG G G PG G KG G G G KG GAPG G G Sbjct: 230 DGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGL 289 Query: 582 SGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLK 641 G GAPGP GP G PG G PG AG +G AR +DG GPPG P Sbjct: 290 PGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDG--------ARGSDGQPGPPGPP--- 338 Query: 642 GDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQ---------GPKGDRGSRGEKGDP 692 G G PG PGAKGEVG G PG G PG+ G GPQ GP G GS G KG+ Sbjct: 339 GTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEM 398 Query: 693 GKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKG 751 G G+ G PGL G GPPGP + G G PG G G GP+G G G Sbjct: 399 GPAGIPGAPGLMGARGPPGPA-----GANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAG 453 Query: 752 ERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRP 811 G PG KGE G+ GS P L P G +G PGFRGP GP G PG KG G G P Sbjct: 454 IPGVPGAKGEDGKDGSPGEPGANGL-PGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAP 512 Query: 812 GRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPP- 870 G G G GE G G G GMRGMPG PG PG G PG P ES RPGPP Sbjct: 513 GPAGPRGAAGEPGRDGVPG-GPGMRGMPGSPGGPGSDGKPGPP----GSQGESGRPGPPG 567 Query: 871 -----GLPGNQGPPGPK------GAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAG 919 G PG G PGPK G GE G PG PG E +G G G G Sbjct: 568 PSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGG 627 Query: 920 QKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGES-------IRGQPGPPGPQGP 972 KG+ G PG G G LPG GPPG G PG PGPKG++ +G G PG +GP Sbjct: 628 DKGDTGPPGPQGLQG--LPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGP 685 Query: 973 PGI----GYEGRQGPPGP------PGPPGPPSFPGP--------HRQTISVPGPPGPPGP 1014 PG+ G G GPPGP GPPGPP G R + PGP G G Sbjct: 686 PGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGE 745 Query: 1015 PGPPGTMG 1022 PG PG G Sbjct: 746 PGGPGADG 753 Score = 238 bits (606), Expect = 4e-62 Identities = 154/369 (41%), Positives = 171/369 (46%), Gaps = 68/369 (18%) Query: 675 GPQGPKGDRGSRGEKGDPGKDGV-GQPGLPGPPGPPG--------PVVYVSEQDGSVLSV 725 GPQGPKGD G G G G G+ GQPG PG PGPPG P Y + D V Sbjct: 103 GPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDS--YDV 160 Query: 726 PGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKG 785 G AG+PGPAGP G PGP G G PGS G Sbjct: 161 KSGVAVGGLAGYPGPAGPPG---------PPGPPGTSGHPGS----------------PG 195 Query: 786 EPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPP 845 PG++GPPG G+ G G G PG G G G GE G PG G RG+PGPPG Sbjct: 196 SPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRP----GERGLPGPPGIK 251 Query: 846 GPPGPPGTPVYDSNVF-----AESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFD 900 GP G PG P + E G PGL G G PG GA G +GP G PG+ Sbjct: 252 GPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGE---- 307 Query: 901 FLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE-- 958 +G G G AG +G G G G PGPPGPPG G+PG PG KGE Sbjct: 308 --------RGRPGLPGAAGARGNDGARGSDG-----QPGPPGPPGTAGFPGSPGAKGEVG 354 Query: 959 --SIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPP 1015 G G PG +G PG G+ G QGPPGPPG G P G +PG PG G Sbjct: 355 PAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKG-EMGPAGIPGAPGLMGAR 413 Query: 1016 GPPGTMGAS 1024 GPPG GA+ Sbjct: 414 GPPGPAGAN 422 Score = 209 bits (531), Expect = 2e-53 Identities = 147/362 (40%), Positives = 161/362 (44%), Gaps = 73/362 (20%) Query: 676 PQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFA 735 P P +G +G KGDPG PG+PG G PG G+PG Sbjct: 95 PTRPPNGQGPQGPKGDPGP-----PGIPGRNGD-----------------PGIPGQPGSP 132 Query: 736 GFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGP 795 G PGP G E GP+ + S G A+G G G PG GPPGP Sbjct: 133 GSPGPPGIC-------ESCPTGPQNYSPQYDSYDVKSGVAVG----GLAGYPGPAGPPGP 181 Query: 796 YGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPV 855 G PG G PG PG G +G GEPG A G G PGPPG GP GP G Sbjct: 182 PGPPGTSGH------PGSPGSPGYQGPPGEPGQA----GPSGPPGPPGAIGPSGPAGKD- 230 Query: 856 YDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDR 915 ES RPG PG G GPPG KG G G PG G FD GEKG+ Sbjct: 231 ------GESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFD------GRNGEKGET 278 Query: 916 GDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKG----ESIRGQPGPPGPQG 971 G G KGE G PG G G GP G PG RG PG+PG G + RG G PGP G Sbjct: 279 GAPGLKGENGLPGENGAPGPM--GPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPG 336 Query: 972 PPGI----GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPG---PPGPPGPPGTMGAS 1024 PPG G G +G GP G PG PG + PGP G GPPGPPG G+ Sbjct: 337 PPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGE----PGPQGHAGAQGPPGPPGINGSP 392 Query: 1025 SG 1026 G Sbjct: 393 GG 394 Score = 187 bits (476), Expect = 4e-47 Identities = 125/310 (40%), Positives = 142/310 (45%), Gaps = 61/310 (19%) Query: 752 ERGSPGPKGEKGE-----PGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIG 806 E P P+ GE P +P G +G KG+PG G PG G PG G+ G Sbjct: 71 ELDCPNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPG 130 Query: 807 FPGRPGRPGM-----NGLKG--EKGEPGDASLGF---GMRGMPGPPGPPGPPGPPGTPVY 856 PG PG PG+ G + + + D G G+ G PGP GPPGPPGPPGT Sbjct: 131 SPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGT--- 187 Query: 857 DSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRG 916 S PG PG PG QGPPG G G GPPGPPG G G Sbjct: 188 -------SGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAI---------------GPSG 225 Query: 917 DAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE-------SIRGQPGPPGP 969 AG+ GE G PG G G LPGPPG GP G PG PG KG +G+ G PG Sbjct: 226 PAGKDGESGRPGRPGERG--LPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGL 283 Query: 970 QGPPGI----GYEGRQGPPGPPGPPGPPSFPGPH--------RQTISVPGPPGPPGPPGP 1017 +G G+ G G GP G PG G P PG R + PGPPGPPG G Sbjct: 284 KGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGF 343 Query: 1018 PGTMGASSGV 1027 PG+ GA V Sbjct: 344 PGSPGAKGEV 353 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 545 bits (1405), Expect = e-155 Identities = 366/891 (41%), Positives = 413/891 (46%), Gaps = 163/891 (18%) Query: 238 DEEGDDSDGASGDSG--SGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSR 295 D+E +G GD+G G A R+ G +P LP PP PP G Sbjct: 104 DQETTGVEGPKGDTGPRGPRGPAGPPGRD--GIPGQPGLPGPPGPPGPPGPPGLG----- 156 Query: 296 SEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAG 355 + Q G D ST SV P G G +G G PG PGP G G Sbjct: 157 ----------GNFAPQLSYGYDEKSTGGISVPGPMG---PSGPRGLPGPPGAPGPQGFQG 203 Query: 356 PPGSPCLPGPPGLPCPVSPLGPAGPALQTV----------PGPQGPPGPPGRDGTPGR-- 403 PPG P G PG P+ P GP GP + PG +GPPGP G G PG Sbjct: 204 PPGEP---GEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAG 260 Query: 404 -------------------------DGEPGDPGEDGKPGDTGPQGFPGT---PGDVGPKG 435 GEPG PGE+G PG GP+G PG PG GP G Sbjct: 261 LPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAG 320 Query: 436 DKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPG 494 +G+ G G GPPGP GP GPPG F + G G E +G RG PGPPG Sbjct: 321 ARGNDGATGAAGPPGPTGPAGPPG--FPGAVGAKGEAGPQGPRGS-EGPQGVRGEPGPPG 377 Query: 495 PPGV------PGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGP 548 P G PG G+PG G N + PG AG PG PG GP G G GPPGP G G Sbjct: 378 PAGAAGPAGNPGADGQPGAKGANGA--PGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGE 435 Query: 549 PGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLP 608 PG G KG G G PG G +G PGPAG G+ G G PGP G PGPPG G PG Sbjct: 436 PGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGF 495 Query: 609 AGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVP------ 662 G D + G GP + R + GP GP G PG G PG GLPGAKG G+ G P Sbjct: 496 PGADGVAGPKGP--AGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKT 553 Query: 663 GFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-------VGQPGLPGPP--------- 706 G PG G++G GP GP G RG G G PG G G+ G+PGPP Sbjct: 554 GPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKD 613 Query: 707 ------GPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGER------G 754 GPPGP E+ GP G PGF G PGPAGP G G GE+ G Sbjct: 614 GEAGAQGPPGPAGPAGER-----GEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLG 668 Query: 755 SPGPKGEKGEPG-----SIFSPDG-----GALG-PAQKGAKGEPGFRGPPGPYGRPGYKG 803 +PGP G +GE G + P G GA G P GAKG+ G G PG G PG +G Sbjct: 669 APGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQG 728 Query: 804 EIGFPGRPGRPGMNGLKGEKGEPG-DASLG-FGMRGMPGPPGPPGPPGPPGTPVYDSNVF 861 G G G PG G +G+ G G D S G G+RG+ GP GPPGP G PG +S Sbjct: 729 MPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDK-GESGPS 787 Query: 862 AESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQK 921 + G G PG++G PGP G G GPPG GQ G KG+ GDAG K Sbjct: 788 GPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQ------------PGAKGEPGDAGAK 835 Query: 922 GERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI------ 975 G+ G PG GP GPPGP G G PG KG RG GPPG G PG Sbjct: 836 GDAGPPGPA--------GPAGPPGPIGNVGAPGAKG--ARGSAGPPGATGFPGAAGRVGP 885 Query: 976 -GYEGRQGPPGPPGPPGPPSFPGPHRQT--ISVPGPPGPPGPPGPPGTMGA 1023 G G GPPGPPGP G GP +T PG GPPGPPGP G G+ Sbjct: 886 PGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGS 936 Score = 533 bits (1372), Expect = e-151 Identities = 370/933 (39%), Positives = 420/933 (45%), Gaps = 157/933 (16%) Query: 187 PLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQ-----VSPMHCLDEEG 241 P +RG + GA G A P F G + K PQ P E G Sbjct: 316 PGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGA-KGEAGPQGPRGSEGPQGVRGEPG 374 Query: 242 DDSD-GASGDSGSGLGDARELLREETGA---ALKPRLPAPPPVTTPPLAGGSSTEDSRSE 297 GA+G +G+ D + + GA A P P + P GG S Sbjct: 375 PPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSG 434 Query: 298 EVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPP 357 E + GA+ PG V G P G + G +G+ G G+PGPPG G P Sbjct: 435 EPGAPGSKGDTGAKGEPGPVGVQGPPG----PAGEEGKRGARGEPGPTGLPGPPGERGGP 490 Query: 358 GSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGR---------DGEPG 408 GS PG G+ P P G G PGP GP G PG G PG G PG Sbjct: 491 GSRGFPGADGVAGPKGPAGERGS-----PGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPG 545 Query: 409 DPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV----------------GERGPPGP-- 450 PG DGK G GP G G PG GP G +G GV GERG PGP Sbjct: 546 SPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPG 605 Query: 451 -------------QGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPG 497 QGPPGP GP+ + G G G +G PGP GPPG Sbjct: 606 AVGPAGKDGEAGAQGPPGPAGPAGERGE--------QGPAGS----PGFQGLPGPAGPPG 653 Query: 498 VPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPG---LPGPPGPPGREGPPGRTGQ 554 G PGE G VPG G PG G G GFPG + GPPGP G G G G Sbjct: 654 EAGKPGEQG--------VPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGN 705 Query: 555 KGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDM 614 G+ G+AGAPG GS+GAPG G GE G AG PGP G G GP G G G D + Sbjct: 706 DGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGS---PGKDGV 762 Query: 615 EGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIA 674 G GP GP GP G PG KG+ G G G G GA G G PG PG G A Sbjct: 763 RGLTGPI--------GPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFA 814 Query: 675 GPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGS----VLSVPGPE 729 GP G G G++GE GD G G G PG GP GPPGP+ V PG Sbjct: 815 GPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGAT 874 Query: 730 GRPGFAGFPGPAGPKGNLGSKG------ERGSPGPKGEKG---EPGSIFSPDGGALGPAQ 780 G PG AG GP GP GN G G + G GP+GE G PG + P G GPA Sbjct: 875 GFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPP--GPPGPA- 931 Query: 781 KGAKGEPGFRGP------PGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDA--SLG 832 G KG PG GP PGP G G +G +G PG+ G G GL G GEPG S Sbjct: 932 -GEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGA 990 Query: 833 FGMRGMPGPPGPPGPPGPPG------------TPVYDSNVFAESSR-----------PGP 869 G RG PGP GPPG GPPG +P D + A+ R PG Sbjct: 991 SGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGA 1050 Query: 870 PGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGG 929 PG PG GP G G +GE GP GP G + A +G +GD+G+ G++G+RG G Sbjct: 1051 PGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGH 1110 Query: 930 GGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI----GYEGRQGPPG 985 GF G L GPPGPPG PG GP G S GP GP+GPPG G +G G PG Sbjct: 1111 RGFSG--LQGPPGPPGS---PGEQGPSGAS-----GPAGPRGPPGSAGAPGKDGLNGLPG 1160 Query: 986 PPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPP 1018 P GPPGP G + PGPPGPPGPPGPP Sbjct: 1161 PIGPPGPRGRTGD-AGPVGPPGPPGPPGPPGPP 1192 Score = 528 bits (1361), Expect = e-149 Identities = 352/818 (43%), Positives = 394/818 (48%), Gaps = 170/818 (20%) Query: 337 GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP-------ALQ------ 383 G++G KG+ G GP G AGPPG +PG PGLP P P GP GP A Q Sbjct: 109 GVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYD 168 Query: 384 -------TVPGPQGP------PGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGD 430 +VPGP GP PGPPG G G G PG+PGE G G GP+G PG PG Sbjct: 169 EKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGK 228 Query: 431 VGPKGDKGDPG-VGERGPPGPQGPPGPPG----PSFR-HDKLTFIDMEGSGFGGDLEALR 484 G G+ G PG GERGPPGPQG G PG P + H + +D G GD Sbjct: 229 NGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLD----GAKGDAGPA- 283 Query: 485 GPRGFPGPPGPPGVPG------LPGEPGRFGV-------NSSDVPGPAGLPGVPGREGPP 531 GP+G PG PG G PG LPGE GR G + G AG PG G GPP Sbjct: 284 GPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPP 343 Query: 532 GFPGL------PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA---PGPAGARGES 582 GFPG GP GP G EGP G G+ G G AGA G G+ GA PG GA G Sbjct: 344 GFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAP 403 Query: 583 GLAGAPG------PAGPPGPPGPPGPPG----PGLPAGFDDMEGSGGPFWSTARSADGPQ 632 G+AGAPG P+GP GP GPPGP G PG P D G P + GP Sbjct: 404 GIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPA 463 Query: 633 GPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGS---RGEK 689 G G G +G+PG GLPG GE G PG G PG +G+AGP+GP G+RGS G K Sbjct: 464 GEEGKRGARGEPGPTGLPGPPGERGG---PGSRGFPGADGVAGPKGPAGERGSPGPAGPK 520 Query: 690 GDPGKDG-------------VGQPGLPGPPG---PPGPVVYVSEQDG--SVLSVPGPEGR 731 G PG+ G G PG PGP G PPGP + QDG PG G+ Sbjct: 521 GSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGP----AGQDGRPGPPGPPGARGQ 576 Query: 732 PGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGP----------AQK 781 G GFPGP G G G GERG PGP G G G + GA GP ++ Sbjct: 577 AGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGK--DGEAGAQGPPGPAGPAGERGEQ 634 Query: 782 GAKGEPGFRGPPGPYGRPGYKG---EIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGM 838 G G PGF+G PGP G PG G E G PG G PG +G +GE+G PG+ RG+ Sbjct: 635 GPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGE-------RGV 687 Query: 839 PGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFP 898 GPPGP GP G G P D G PG PG+QG PG +G GE G G PG Sbjct: 688 QGPPGPAGPRGANGAPGNDG----AKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGP-- 741 Query: 899 FDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE 958 KGDRGDAG KG G PG G G L GP GPPGP G PG G G Sbjct: 742 -------------KGDRGDAGPKGADGSPGKDGVRG--LTGPIGPPGPAGAPGDKGESGP 786 Query: 959 S-------------IRGQPGPPGPQG---PPGI----------GYEGRQGPPGPPGPPGP 992 S RG+PGPPGP G PPG G G +G GPPGP GP Sbjct: 787 SGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGP 846 Query: 993 PSFPGPHRQTISVPGPPGP---PGPPGPPGTMGASSGV 1027 PGP + PG G GPPG G GA+ V Sbjct: 847 AGPPGPIGN-VGAPGAKGARGSAGPPGATGFPGAAGRV 883 Score = 527 bits (1357), Expect = e-149 Identities = 347/839 (41%), Positives = 386/839 (46%), Gaps = 111/839 (13%) Query: 245 DGASGDSGSGLGDARELLREETGAA--LKPR-LPAPPPVTTPPLAGGSSTEDSRSEEVEE 301 DGA GD+G E GA + PR LP P G+ D + Sbjct: 274 DGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGP 333 Query: 302 QTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPC 361 G PG+ G G R EG +G +GEPG PGP G AGP G+P Sbjct: 334 PGPTGPAGPPGFPGAVGAK---GEAGPQGPRGSEGP-QGVRGEPGPPGPAGAAGPAGNPG 389 Query: 362 LPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGP 421 G PG G AG PG +GP GP G G PG G G+PG G GDTG Sbjct: 390 ADGQPGAKGANGAPGIAGAP--GFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGA 447 Query: 422 QGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDL 480 +G PG G GP G G+ G G RG PGP G PGPPG F +G + Sbjct: 448 KGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADG------V 501 Query: 481 EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP 540 +GP G G PGP G G PGE GR G + +PG GL G PG GP G G PGP Sbjct: 502 AGPKGPAGERGSPGPAGPKGSPGEAGRPG--EAGLPGAKGLTGSPGSPGPDGKTGPPGPA 559 Query: 541 GPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPP 600 G GR GPPG G +G G G PG KG+ G PG AG RG G GA GPAG G G Sbjct: 560 GQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQ 619 Query: 601 GPPGPGLPAGFDDMEGSGGPFWSTA-RSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGAD 659 GPPGP PAG G GP S + GP GPPG G G+ GVPG GA G GA Sbjct: 620 GPPGPAGPAG---ERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGAR 676 Query: 660 GVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQ 718 G GFPG G+ GP GP G RG+ G G+ G G G PG PG G PG Sbjct: 677 GERGFPG---ERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPG-------- 725 Query: 719 DGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGP 778 + G G G AG PGP G +G+ G KG GSPG G +G G I P G A P Sbjct: 726 ------LQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPI-GPPGPAGAP 778 Query: 779 AQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPG---RPGMNGLKGEKGEPGDASLGFGM 835 KG G G GP G G PG +GE G PG G PG +G G KGEPGDA G Sbjct: 779 GDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDA----GA 834 Query: 836 RGMPGPPGPPGPPGPPGT-----------------PVYDSNVFAESSRPGPPGLPGNQGP 878 +G GPPGP GP GPPG P + + R GPPG GN GP Sbjct: 835 KGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGP 894 Query: 879 PGPKGAKG------------------EVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQ 920 PGP G G EVGPPGPPG GEKG G G Sbjct: 895 PGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGP------------AGEKGSPGADGP 942 Query: 921 KGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIPGPKGE-------SIRGQPGPPGPQGP 972 G G PG G G + G PG G RG+PG+PGP GE G+ GPPGP GP Sbjct: 943 AGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGP 1002 Query: 973 PGI----GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGV 1027 PG+ G GR+G PG G PG PG G GP GPPG PG GA V Sbjct: 1003 PGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDR----GETGPAGPPGAPGAPGAPGPV 1057 Score = 495 bits (1274), Expect = e-139 Identities = 335/844 (39%), Positives = 374/844 (44%), Gaps = 187/844 (22%) Query: 351 PGRAGPPGSPCLPGPPGLPCPVSP--LGPAGPALQTVP-GPQGPPGPPGRDGTPGRDGEP 407 PG P G C P G P G GP T P GP+GP GPPGRDG PG+ G P Sbjct: 82 PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLP 141 Query: 408 GDPGEDGKPGDTGPQGFPGTP---GDVGPK-----GDKGDPGVGERGPPGPQGPPGPPGP 459 G PG P G PG P G+ P+ +K G+ GP GP GP G PGP Sbjct: 142 GPPG---------PPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGP 192 Query: 460 SFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFG-------VNS 512 F G GPRG PGPPG G G G+PGR G + Sbjct: 193 PGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGA 252 Query: 513 SDVPGPAGLPGVPGREGPPGFPGL---PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGS 569 +PG AGLPG+ G G G G GP GP G G PG G G +G G PG +G Sbjct: 253 RGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGR 312 Query: 570 KGAPGPAGARGE---SGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTAR 626 GAPGPAGARG +G AG PGP GP GPPG PG G AG GS GP R Sbjct: 313 PGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGP--QGVR 370 Query: 627 SADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSR 686 GP GP G G G+PG G PGAKG GA G+ G PG PG G +GPQGP G G + Sbjct: 371 GEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPK 430 Query: 687 GEKGDPGKDG-------VGQPGLPGPPGPPGPVVYVSEQ----DGSVLSVPGPEGR---P 732 G G+PG G G+PG G GPPGP ++ + +PGP G P Sbjct: 431 GNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGP 490 Query: 733 GFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGP 792 G GFPG G G G GERGSPGP G KG PG P L P KG G PG GP Sbjct: 491 GSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGL-PGAKGLTGSPGSPGP 549 Query: 793 PGPYGRPGYKGEIGFPGRPGRPGMNGL---------KGEKGEPGDASLGFGMRGMPGPP- 842 G G PG G+ G PG PG PG G KG GEPG A G RG+PGPP Sbjct: 550 DGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA----GERGVPGPPG 605 Query: 843 --------------GPPGP---------PGPPGTPVYD-----SNVFAESSRPGPPGLPG 874 GPPGP GP G+P + + E+ +PG G+PG Sbjct: 606 AVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPG 665 Query: 875 NQGPPGPKGAKGE---------VGPPGP------------------------------PG 895 + G PGP GA+GE GPPGP PG Sbjct: 666 DLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPG 725 Query: 896 QFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGP 955 + A + G KGDRGDAG KG G PG G G L GP GPPGP G PG G Sbjct: 726 LQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRG--LTGPIGPPGPAGAPGDKGE 783 Query: 956 KGES-------------IRGQPGPPGP---QGPPG-------------IGYEGRQGPPGP 986 G S RG+PGPPGP GPPG G +G GPPGP Sbjct: 784 SGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGP 843 Query: 987 PGPPGPP------------------------SFPGPHRQTISVPGPPGPPGPPGPPGTMG 1022 GP GPP FPG + + PGP G GPPGPPG G Sbjct: 844 AGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGR-VGPPGPSGNAGPPGPPGPAG 902 Query: 1023 ASSG 1026 G Sbjct: 903 KEGG 906 Score = 408 bits (1048), Expect = e-113 Identities = 271/667 (40%), Positives = 304/667 (45%), Gaps = 97/667 (14%) Query: 267 GAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSV 326 GAA +P V PP A G + +D + GAQ PG Sbjct: 587 GAAGEPGKAGERGVPGPPGAVGPAGKDGEA------------GAQGPPG----------- 623 Query: 327 RTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG------- 379 P G E G +G G PG G PG AGPPG PG G+P + GP+G Sbjct: 624 --PAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGF 681 Query: 380 PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGD------VGP 433 P + V GP GP GP G +G PG DG GD G G PG G G G PG+ GP Sbjct: 682 PGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGP 741 Query: 434 KGDKGDPG----------------VGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFG 477 KGD+GD G G GPPGP G PG G S G+ Sbjct: 742 KGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGD 801 Query: 478 GDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNS-SDVPGPAGLPGVPGREGPPGFPGL 536 GP GF GPPG G PG GEPG G + PGPAG G PG P G G Sbjct: 802 RGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPG---PIGNVGA 858 Query: 537 PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGP 596 PG G G GPPG TG G+ G G PG G+ G PGP G G+ G G G GP G Sbjct: 859 PGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGR 918 Query: 597 PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPG------LPGLKGDPGVPGLP 650 PG GPPGP PAG G+ GP + A GPQG G LPG +G+ G PGLP Sbjct: 919 PGEVGPPGPPGPAGEKGSPGADGP--AGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLP 976 Query: 651 GAKGEVG------ADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-------- 696 G GE G A G G PG G G+AGP G G G+ G +G PG+DG Sbjct: 977 GPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDR 1036 Query: 697 -----VGQPGLPGPPGPPGPVVYVSEQ-DGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSK 750 G PG PG PG PGPV + D GP G G G GPAGP+G G K Sbjct: 1037 GETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDK 1096 Query: 751 GERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGR 810 GE G G +G KG G FS G GP G G PG +GP G G G +G G G Sbjct: 1097 GETGEQGDRGIKGHRG--FS---GLQGPP--GPPGSPGEQGPSGASGPAGPRGPPGSAGA 1149 Query: 811 PGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPP 870 PG+ G+NGL G G PG G G GP GPPGPPGPPG P S F S P PP Sbjct: 1150 PGKDGLNGLPGPIGPPGPR----GRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPP 1205 Query: 871 GLPGNQG 877 + G Sbjct: 1206 QEKAHDG 1212 Score = 242 bits (618), Expect = 2e-63 Identities = 163/426 (38%), Positives = 180/426 (42%), Gaps = 64/426 (15%) Query: 246 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 305 G G+SG R G +P P P PP A G + E + Sbjct: 779 GDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADG---QPGAKGEPGDAGAK 835 Query: 306 ASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGP 365 G G G+V PG + G G G G PG GR GPPG GP Sbjct: 836 GDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSA-GPPGATGFPGAAGRVGPPGPSGNAGP 894 Query: 366 PGLPCPVSPLGPAGPALQTVP-------GPQGPPGPPGRDGTPGRDGEPGDPGEDGK--- 415 PG P P G GP +T P GP GPPGP G G+PG DG G PG G Sbjct: 895 PGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGI 954 Query: 416 ---------PGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDK 465 PG G +GFPG PG G G +G G GERGPPGP GPPG GP + Sbjct: 955 AGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGR 1014 Query: 466 LTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGV-------NSSDVPGP 518 EGS +G RG GP GPPG PG PG PG G + GP Sbjct: 1015 EGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGP 1074 Query: 519 AGLPGVPGREGPPG------------------------FPGLPGPPGPPG---REGPPGR 551 AG G G GP G F GL GPPGPPG +GP G Sbjct: 1075 AGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGA 1134 Query: 552 TGQ---KGSLGEAGAPGHKGSKGAPGPAGA---RGESGLAGAPGPAGPPGPPGPPGPPGP 605 +G +G G AGAPG G G PGP G RG +G AG GP GPPGPPGPPGPP Sbjct: 1135 SGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSA 1194 Query: 606 GLPAGF 611 G F Sbjct: 1195 GFDFSF 1200 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 543 bits (1398), Expect = e-154 Identities = 372/895 (41%), Positives = 424/895 (47%), Gaps = 185/895 (20%) Query: 315 GSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGP---PGSPCLPGPPGLP-C 370 G V+ G PG + G Q G+PG+PG PGR G PG P LPG PGLP Sbjct: 635 GIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGI 694 Query: 371 PVSPLGPAGPA--LQTVPGPQGP---PGPPGRDGTPGR---DGEPGDPGEDGK------- 415 P S P P L PGP+G PGPPG GTPGR +G PG PG G Sbjct: 695 PGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFA 754 Query: 416 -PGDTGPQGFPGTPGDVGPKGDKGDPG-------------------VGERGPPGPQGPPG 455 PG GP G PG G +GPKGD+G PG VG G PGP GPPG Sbjct: 755 LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPG 814 Query: 456 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 515 PG I ++G GP G PGP G PG+ G+PGE G G DV Sbjct: 815 LPG----------IGVQGP---------PGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV 855 Query: 516 PGP------AGLPGVPGREGPPGFPGLP------------------GPPGPPGREGPPGR 551 PGP G+PG PG GPPG PGLP GPPGPPG G PGR Sbjct: 856 PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915 Query: 552 TGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGP--------PGPPGPPGPP 603 +G G G+ G G G G G G++GE GL G PGP P G PG PG P Sbjct: 916 SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975 Query: 604 GPGLPAGFDDMEGS-GGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVP 662 G P G+ + G G P S GP GP G PGL G PG+ G PG KG +G G P Sbjct: 976 GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFP 1035 Query: 663 GFPGL---PGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPG-------PV 712 G G+ PG G+ G G G G +G+KGDPG +G PGLPGP G PG P Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPG 1095 Query: 713 VYVSEQDGSVLSVPGPEGR------PGFAGFPGPAGPK---------------GNLGSKG 751 + S D + +PG G PGF G PGP GPK G +G G Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155 Query: 752 ERGSPGPKGEKGEPGSIFSPDGGALGPA-QKGAKGEPGFRGPPGPYGRPGYKGEIGFPGR 810 G PGP GEKG+PG G GPA QKG G+PGF G PGP G PG G+ G G Sbjct: 1156 HPGQPGPPGEKGKPG-----QDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGL 1209 Query: 811 PGRPGMNGLKGEKGEPGDASLGF-GMRGMPGPPGPPGP--PGPPGTPVYDSNVFAESSRP 867 PG PG GL G KGEPG GF G++G PGPPG PGP GP G P P Sbjct: 1210 PGIPGNPGLPGPKGEPG--FHGFPGVQGPPGPPGSPGPALEGPKGNP-------GPQGPP 1260 Query: 868 GPPGLPGNQGPP------GPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQK 921 G PGLPG +GPP G KG KG G PG PG Q ++G G G G K Sbjct: 1261 GRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMK 1320 Query: 922 GERGEPGGGGFFG----SSLPGPPGPP------GPRGYPGIPGPKGES--IRGQPGPPGP 969 G+ G PG GF G S +PG GP GP G PG+PGP G+S I+G GPPG Sbjct: 1321 GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGI 1380 Query: 970 QGPPGI-GYEGRQGPPGPPGPPGPPSFPGPH--------------------RQTISVPGP 1008 G PG+ G G QGP G PGP GPP PG + T + GP Sbjct: 1381 PGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGP 1440 Query: 1009 PGP---PGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVR 1060 PGP GPPGPPGT + G + TR + + P+G L LYV+ Sbjct: 1441 PGPDGLQGPPGPPGTSSVAHGFLI--TRHSQTTDAPQCPQGTLQVYEGFSLLYVQ 1493 Score = 535 bits (1377), Expect = e-151 Identities = 365/926 (39%), Positives = 421/926 (45%), Gaps = 193/926 (20%) Query: 243 DSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQ 302 D G G+ G R G P LP P PP G +D + Sbjct: 39 DCSGIKGEKGE---------RGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPK 89 Query: 303 TTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSP 360 G PG+ + G PG + G G KG++G PG PG PG GPPG P Sbjct: 90 GIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPP 149 Query: 361 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGP---PGPPGRDGTPGRDGEPGDPGEDGKPG 417 +PG G P + + ++PGP+G PGPPG G PG G PG G G PG Sbjct: 150 GIPGMKGEPGSI--------IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPG 201 Query: 418 DTGPQGFPGTPGD--------VGPKGDKGDPGV--------------------------- 442 GP G PG PG GPKG+KG+ G+ Sbjct: 202 LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261 Query: 443 --GERGPPGP---QGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPG 497 G+RGPPGP +GPPGPPG + +K +G G G PG PG PG Sbjct: 262 LPGDRGPPGPPGIRGPPGPPGGE-KGEK----GEQGEPGKRGKPGKDGENGQPGIPGLPG 316 Query: 498 VPGLPGEPGRFG----VNSSDVPGP-------------------AGLPGVPGREGPPGFP 534 PG PGEPGR G + PGP GLPG+PG +G GFP Sbjct: 317 DPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFP 376 Query: 535 GLPGPPGPP--------GREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAG 586 G+ GPPG P G GPPG G++G G+ G PG G PG G G GL G Sbjct: 377 GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPG-ISIPGPPGLDGQPGAPGLPG 435 Query: 587 APGPAGP----------PGPPGPPGPPGPGLPAGFDDMEGSGGP--FWSTARSADGPQGP 634 PGPAGP PGPPGPPG PG G ++G G F GP G Sbjct: 436 PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495 Query: 635 PGLPGLKGDPGVPGLPGAKGE------VGADGVPGFPGLPGREGIAGPQGPKGD------ 682 PGLPGL G PG G PG KGE G G+PG PG PG G G +G GD Sbjct: 496 PGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG 555 Query: 683 -RGSRGEKGDPGKDGV----------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGR 731 +G +GE G PG G+ G PGLPGP G PG + + E+ GP G Sbjct: 556 MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGER--------GPPGN 607 Query: 732 PGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFR- 790 PG G PG GP G G G PGP GEKG G +P P G KG+PG Sbjct: 608 PGLPGLPGNIGPMGPPGF----GPPGPVGEKGIQGVAGNPG----QPGIPGPKGDPGQTI 659 Query: 791 ---GPPGPYGRPGYKGEIGF---PGRPGRPGMNGLKGEKGEPGDASLGF-------GMRG 837 G PG G PG G++G PG PG+PG+ G+ G KGEPG +G G G Sbjct: 660 TQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPG 719 Query: 838 MPGPPGPP---------GPPGPPGTPVYDSNV-FAESSRPGPPGLPGNQGPPGPKGAKGE 887 +PGPPG P GPPGPPG P FA PGPPGLPG +G GPKG +G Sbjct: 720 IPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF 779 Query: 888 VGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPR 947 GPPGPPG+ D L G KGD G GQ G G PG G PGPPG PGP Sbjct: 780 PGPPGPPGRTGLDGL------PGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPI 833 Query: 948 GYPGIPGPKGESIRGQPGPPG--PQGPPG-IGYEGRQGPPGPPGPPGPPSFPGP------ 998 G PG+ G GE +G PGPPG GPPG G G G PGP GPPG P PG Sbjct: 834 GQPGLHGIPGE--KGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGF 891 Query: 999 --HRQTISVPGPPGPPGPPGPPGTMG 1022 + + + GPPGPPGP G PG G Sbjct: 892 PGTKGEMGMMGPPGPPGPLGIPGRSG 917 Score = 528 bits (1360), Expect = e-149 Identities = 344/783 (43%), Positives = 387/783 (49%), Gaps = 131/783 (16%) Query: 328 TPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPG 387 +PG + G+KG+KGE G PG G G PG P GPPG G GP PG Sbjct: 33 SPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGP-----PG 87 Query: 388 PQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGP 447 P+G GPPG G PG G PG PG DG P GPQG PG G G +G G PG Sbjct: 88 PKGIRGPPGLPGFPGTPGLPGMPGHDGAP---GPQGIPGCNGTKGERGFPGSPGF----- 139 Query: 448 PGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGR 507 PG QGPPGPPG M+G + +L GP+G PG PGPPG+ GLPG G Sbjct: 140 PGLQGPPGPPG---------IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTG- 189 Query: 508 FGVNSSDVPGPAGLPGVPGREGPPGFPGLPGP--------------PGPPGREGPPGRTG 553 +PGP G PG PG GPPG PGLPGP G G +GPPG G Sbjct: 190 -------IPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPG 242 Query: 554 Q----------------KGSLGEAGAPGHKGSKGAPG-PAGARGESGLAGAPGPAGPPGP 596 Q +G G+ G PG G +G PG P G +GE G G PG G PG Sbjct: 243 QISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGK 302 Query: 597 PGPPGPPG-PGLPAGFDDMEGSGGPFWSTARSAD-GPQGPPGLP----------GLKGDP 644 G G PG PGLP G G G + D GP GPPGL G KG+ Sbjct: 303 DGENGQPGIPGLP-GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNI 361 Query: 645 GVPGLPGAKGEVGADGVPGFPGLPGREGIA--GPQGPKGDRGSRGEKGDPGKDGV----- 697 G+PGLPG KGE G G+ G PGLPG G A GP GP G G RG+KGD G G+ Sbjct: 362 GLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP 421 Query: 698 -------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSK 750 G PGLPGPPGP GP + S++ + PGP G PG G G G +G G K Sbjct: 422 PGLDGQPGAPGLPGPPGPAGPHIPPSDE----ICEPGPPGPPGSPGDKGLQGEQGVKGDK 477 Query: 751 GE-------RGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKG 803 G+ G GP G+ G PG + P G P QKG KG+ G GP G G PG G Sbjct: 478 GDTCFNCIGTGISGPPGQPGLPG-LPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPG 536 Query: 804 EIGFPGRPGR-------PGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTP-- 854 GFPG G PGM G KGE G PG L G+ G PG G PG PGP G P Sbjct: 537 APGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP-GLPGTPGQDGLPGLPGPKGEPGG 595 Query: 855 VYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGD 914 + PG PGLPGN GP GP G GPPGP G+ + G G Sbjct: 596 ITFKGERGPPGNPGLPGLPGNIGPMGPPG----FGPPGPVGEKGIQGVAGNPGQPGIPGP 651 Query: 915 RGDAG----QKGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIPGPKGE---SIRGQPGP 966 +GD G Q G+ G PG G G LPG PG PG G PGIPG KGE G PGP Sbjct: 652 KGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP 711 Query: 967 PGPQGPPGIGYEGRQGPPGPP------GPPGPPSFPGPHRQT-ISVPGPPGPPGPPGPPG 1019 PGP+G PGI G G PG P GPPGPP FPGP + ++PGPPGPPG PG G Sbjct: 712 PGPKGFPGI--PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG 769 Query: 1020 TMG 1022 +G Sbjct: 770 ALG 772 Score = 442 bits (1137), Expect = e-123 Identities = 277/640 (43%), Positives = 316/640 (49%), Gaps = 79/640 (12%) Query: 314 PGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPG--------- 364 PG + G PG V G G++G PG+PG PG GPPGSP LPG Sbjct: 836 PGLHGIPGEKGDPGPPGLDVP--GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPG 893 Query: 365 ---------PPGLPCPVSPLGPAG-PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDG 414 PPG P P+ G +G P L+ G QG PG PG G G GEPG PG G Sbjct: 894 TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG 953 Query: 415 --------KPGDTGPQGFPGTPGDVGPKGDKGDPG----VGERGPPGPQGPPGPPGPSFR 462 G+ G G PG PG GPKG +G PG G G PG GPPGP G Sbjct: 954 PMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGL 1013 Query: 463 HDKLTFIDMEG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPA-- 519 + I G G GD+ GP+G GPPGP GVPG PG PG G D P Sbjct: 1014 PGQPGLIGPPGLKGTIGDM-GFPGPQGVEGPPGPSGVPGQPGSPGLPG-QKGDKGDPGIS 1071 Query: 520 --GLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAG 577 GLPG+PG +G PG PG PG PG G G PG G G+ G G PG G G PGP G Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131 Query: 578 ARGESGLAGAPGPAGPPGP------PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGP 631 +G SG G PG G PGP PG PGPPG G D + G G + G Sbjct: 1132 PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGN 1191 Query: 632 QGPPGLPGL---KGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGE 688 GPPGLPGL KGD G+PG+PG G G G PGF G PG +G GP G G G Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP-ALEGP 1250 Query: 689 KGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNL 747 KG+PG G G+PGLPGP GPPG +G + G G+PG G PG G +G Sbjct: 1251 KGNPGPQGPPGRPGLPGPEGPPG-----LPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPP 1305 Query: 748 GSKGERGSPGPKGEKGEPGSIFSP-----DGGALGPAQKGAKGEPGFRGPPGPYGRPG-- 800 G +G G PG G KG+PG P G + P G +GEPG GPPGP G PG Sbjct: 1306 GLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPS 1365 Query: 801 -----YKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPV 855 KG+ G PG PG+PG+ GL G +G +G+PGP GPPG PG G P Sbjct: 1366 GQSIIIKGDAGPPGIPGQPGLKGLPGPQGP----------QGLPGPTGPPGDPGRNGLPG 1415 Query: 856 YDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPG 895 +D PG PG PG +G GP G G GPPGPPG Sbjct: 1416 FD-GAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1454 Score = 399 bits (1026), Expect = e-111 Identities = 256/609 (42%), Positives = 291/609 (47%), Gaps = 112/609 (18%) Query: 265 ETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDG 324 E G+ +P LP PP P L G S+ E+ E G +PG + G Sbjct: 939 EKGSKGEPGLPGPPGPMDPNLLG------SKGEKGEP-------GLPGIPGVSGPKGYQG 985 Query: 325 SVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP-ALQ 383 PG + GL GQ G PG PGP G G PG P L GPPGL + +G GP ++ Sbjct: 986 LPGDPG----QPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVE 1041 Query: 384 TVPGPQGPPGPPGRDGTPGRDGEPGDPGED-----GKPGDTGPQGFPGTPGDVGPKGDKG 438 PGP G PG PG G PG+ G+ GDPG G PG G G PG PG+ G KG G Sbjct: 1042 GPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVG 1101 Query: 439 DPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPG 491 DPG+ G +G PG G PG PGP GP+G G Sbjct: 1102 DPGLPGLPGTPGAKGQPGLPGFPGTPGPP------------------------GPKGISG 1137 Query: 492 PPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP--GREGPP 549 PPG PG+PG PG G G PGP G G PG++G PG G G PG P G GPP Sbjct: 1138 PPGNPGLPGEPGPVG--GGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPP 1195 Query: 550 GRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPA 609 G G G G+ G PG G+ G PGP +GE G G PG GPPGPPG PGP Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGP---KGEPGFHGFPGVQGPPGPPGSPGP------- 1245 Query: 610 GFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPG 669 + +G+ GP GP G PGLPG +G PG+PG G KGE G G PG PGLPG Sbjct: 1246 ALEGPKGNPGP--------QGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPG 1297 Query: 670 REGIAGP---QGPKGDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSV 725 +G GP QG G G G KGDPG GV G PG+ GP G PG Sbjct: 1298 LKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSA------------- 1344 Query: 726 PGPEGRPGFAGFPGPAGPKGNLG-SKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAK 784 GPEG PG G PGP G G G S +G GP G G+PG KG Sbjct: 1345 -GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPG-------------LKGLP 1390 Query: 785 GEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGP 844 G G +G PGP G PG G G PG G G G G G+PG G+ G PGP G Sbjct: 1391 GPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTR----GLDGPPGPDGL 1446 Query: 845 PGPPGPPGT 853 GPPGPPGT Sbjct: 1447 QGPPGPPGT 1455 Score = 398 bits (1022), Expect = e-110 Identities = 267/677 (39%), Positives = 316/677 (46%), Gaps = 147/677 (21%) Query: 425 PGTPGDV-GPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEAL 483 PG+ D G KG+KG ERG PG +G PG PG Sbjct: 34 PGSKCDCSGIKGEKG-----ERGFPGLEGHPGLPG------------------------F 64 Query: 484 RGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP 543 GP G PGP G G G+PG PG G+ GP GLPG PG PG PG+PG G P Sbjct: 65 PGPEGPPGPRGQKGDDGIPGPPGPKGIR-----GPPGLPGFPGT---PGLPGMPGHDGAP 116 Query: 544 GREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGA------PGPAGPPGPP 597 G +G PG G KG G G+PG G +G PGP G G G G+ PGP G PG P Sbjct: 117 GPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYP 176 Query: 598 GPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVG 657 GPPG G P G GP GPPG PGL G PG PGLPG KG +G Sbjct: 177 GPPGIQGLPGPTGIP-----------------GPIGPPGPPGLMGPPGPPGLPGPKGNMG 219 Query: 658 ADGVPGFPGLPGREGIAGPQGP----------------KGDRGSRGEKGDPGKDGVGQPG 701 + G G G +G+ GP GP KGD+G G++G PG PG Sbjct: 220 LN-FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP-----PG 273 Query: 702 LPGPPGPPGPVVYVSEQDGSV-----LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSP 756 + GPPGPPG + G G G+PG G PG G G G GE+G Sbjct: 274 IRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQK 333 Query: 757 GPKGEKGEPGSIFSPDG--------GALG----PAQKGAKGEPGFRGPPGPYGRPGYKGE 804 G G G PG + G G +G P +KG +G PG +GPPG G PG Sbjct: 334 GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG-AAV 392 Query: 805 IGFPGRPGRPGMNGLKGEKGEPGDASLGF-GMRGMPGPPGPPGPPGPPGTPVYDSNVFAE 863 +G PG PG PG G KG++G PG + G G+ G PG PG PGPPGP G + S+ E Sbjct: 393 MGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICE 452 Query: 864 SSRPGPPGLPGNQGPPGPKGAKGEVG-------------PPGPPGQFPFDFLQLEAEMKG 910 PGPPG PG++G G +G KG+ G PPG PG G Sbjct: 453 PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512 Query: 911 EKGDRGDAGQKGERG------EPGGGGFFGS--------SLPGPPGP------PGPRGYP 950 +KG++G AG G +G PG GF GS + PG G PG G P Sbjct: 513 QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572 Query: 951 GIPGPKGESIRGQPGPPGPQGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPP 1009 G+PG G+ G PG PGP+G PG I ++G +GPPG PG PG P GP GPP Sbjct: 573 GLPGTPGQD--GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPM-------GPP 623 Query: 1010 G--PPGPPGPPGTMGAS 1024 G PPGP G G G + Sbjct: 624 GFGPPGPVGEKGIQGVA 640 Score = 386 bits (992), Expect = e-107 Identities = 260/666 (39%), Positives = 299/666 (44%), Gaps = 151/666 (22%) Query: 500 GLPGEPGR-FGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSL 558 G P E +G + +G+ G G G PG G PG PG PG EGPPG GQKG Sbjct: 21 GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80 Query: 559 GEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSG 618 G G PG KG +G PG G G GL G PG G PGP G PG G GF G Sbjct: 81 GIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP 140 Query: 619 GPFWSTARSADGPQGPPGLPGLKGDPG---VPGLPGAKGEVGADGVPGFPGLPGREGIAG 675 G GP GPPG+PG+KG+PG + LPG KG G G PG GLPG GI G Sbjct: 141 G--------LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPG 192 Query: 676 PQGPKGDRGSRGEKGDPGKDG---------------VGQPGLPGPPGPPGPV-------- 712 P GP G G G G PG G G+ GL GPPGPPG + Sbjct: 193 PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252 Query: 713 VYVSEQDGSVLSVPGPEGRPGFAGFPGP----AGPKGNLGSKGERGSPGPKGEKGEPGSI 768 V + D + GP G PG G PGP G KG G G+RG PG GE G+PG Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312 Query: 769 FSP-DGGALG-PAQKGAKGEPGFRGPPGP----------------------YGRPGYKGE 804 P D G G P + G KG+ G GPPGP G PG KGE Sbjct: 313 GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372 Query: 805 IGFP-----------------GRPGRPGMNGLKGEKGEPGDASLGF----GMRGMPGPPG 843 GFP G PG PG G +G+KG+ G + G+ G PG PG Sbjct: 373 RGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPG 432 Query: 844 PPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE-------------VGP 890 PGPPGP G + S+ E PGPPG PG++G G +G KG+ GP Sbjct: 433 LPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGP 492 Query: 891 PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGER------GEPGGGGFFGS--------- 935 PG PG G+KG++G AG G + G PG GF GS Sbjct: 493 PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT 552 Query: 936 -----------------SLPGPPGPPGPRGYPGIPGPKGE----SIRGQPGPPGPQGPPG 974 LPG PG PG G PG+PGPKGE + +G+ GPPG G PG Sbjct: 553 FPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPG 612 Query: 975 I-GYEGRQGPP--GPPGP------------PGPPSFPGPH---RQTISVPGPPGPPGPPG 1016 + G G GPP GPPGP PG P PGP QTI+ PG PG PG PG Sbjct: 613 LPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPG 672 Query: 1017 PPGTMG 1022 G +G Sbjct: 673 RDGDVG 678 Score = 243 bits (621), Expect = 7e-64 Identities = 158/371 (42%), Positives = 183/371 (49%), Gaps = 63/371 (16%) Query: 681 GDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGP 740 G +G +GE+G PG +G PGLPG PGP GP PGP G+ G G PGP Sbjct: 42 GIKGEKGERGFPGLEG--HPGLPGFPGPEGP--------------PGPRGQKGDDGIPGP 85 Query: 741 AGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPG 800 GPKG G G G PG G G PG +P + P G KGE GF G PG G G Sbjct: 86 PGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGI-PGCNGTKGERGFPGSPGFPGLQG 144 Query: 801 YKGEIGFPGRPGRPG---MNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYD 857 G G PG G PG M+ L G KG PG G++G+PGP G PGP GPPG P Sbjct: 145 PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPP-GIQGLPGPTGIPGPIGPPGPP--- 200 Query: 858 SNVFAESSRPGPPGLPGN--------QGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMK 909 PGPPGLPG QGP G KG +G GPPGPPGQ ++ E Sbjct: 201 ----GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEF- 255 Query: 910 GEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPG-PKGESIRGQPGPPG 968 QKG++G PG G PPGPPG RG PG PG KGE +G+ G PG Sbjct: 256 ----------QKGDQGLPGDRG--------PPGPPGIRGPPGPPGGEKGE--KGEQGEPG 295 Query: 969 PQGPPGIGYEGRQGPPGPPGPPGPPSFPG-PHRQTISVPGPPGPPGPPGPPGTMGASSGV 1027 +G PG +G G PG PG PG P +PG P R G G GPPGPPG + G Sbjct: 296 KRGKPG--KDGENGQPGIPGLPGDPGYPGEPGRD--GEKGQKGDTGPPGPPGLVIPRPGT 351 Query: 1028 RLWATRQAMLG 1038 + + +G Sbjct: 352 GITIGEKGNIG 362 Score = 157 bits (398), Expect = 5e-38 Identities = 119/323 (36%), Positives = 142/323 (43%), Gaps = 43/323 (13%) Query: 817 NGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQ 876 +G+KGEKGE G L G G+PG PGP GPPGP G + PGPPG G + Sbjct: 41 SGIKGEKGERGFPGLE-GHPGLPGFPGPEGPPGPRGQK-------GDDGIPGPPGPKGIR 92 Query: 877 GPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSS 936 GPPG G G G PG PG G +G G G KGERG PG GF Sbjct: 93 GPPGLPGFPGTPGLPGMPGH---------DGAPGPQGIPGCNGTKGERGFPGSPGF---- 139 Query: 937 LPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFP 996 PG GPPGP G PG+ G G I PGP+G PG GPPG G PGP P Sbjct: 140 -PGLQGPPGPPGIPGMKGEPGSIIMSSL--PGPKGNPGY-----PGPPGIQGLPGPTGIP 191 Query: 997 GPHRQTISVPGPPGPPGPPGPPGTMG--ASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQ 1054 GP I PGPPG GPPGPPG G + G+ + Q + P G ++EQ Sbjct: 192 GP----IGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQ 247 Query: 1055 EE-LYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPW 1113 + + V Q G + P RG PP + + P +P Sbjct: 248 KRPIDVEFQKG------DQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPG 301 Query: 1114 R-ADDILASPPRLPEPQPYPGAP 1135 + ++ P LP YPG P Sbjct: 302 KDGENGQPGIPGLPGDPGYPGEP 324 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 541 bits (1394), Expect = e-153 Identities = 373/901 (41%), Positives = 425/901 (47%), Gaps = 194/901 (21%) Query: 315 GSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGP---PGSPCLPGPPGLP-C 370 G V+ G PG + G Q G+PG+PG PGR G PG P LPG PGLP Sbjct: 635 GIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGI 694 Query: 371 PVSPLGPAGPA--LQTVPGPQGP---PGPPGRDGTPGR---DGEPGDPGEDGK------- 415 P S P P L PGP+G PGPPG GTPGR +G PG PG G Sbjct: 695 PGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFA 754 Query: 416 -PGDTGPQGFPGTPGDVGPKGDKGDPG-------------------VGERGPPGPQGPPG 455 PG GP G PG G +GPKGD+G PG VG G PGP GPPG Sbjct: 755 LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPG 814 Query: 456 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 515 PG I ++G GP G PGP G PG+ G+PGE G G DV Sbjct: 815 LPG----------IGVQGP---------PGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV 855 Query: 516 PGP------AGLPGVPGREGPPGFPGLP------------------GPPGPPGREGPPGR 551 PGP G+PG PG GPPG PGLP GPPGPPG G PGR Sbjct: 856 PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915 Query: 552 TGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGP--------PGPPGPPGPP 603 +G G G+ G G G G G G++GE GL G PGP P G PG PG P Sbjct: 916 SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975 Query: 604 GPGLPAGFDDMEGS-GGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVP 662 G P G+ + G G P S GP GP G PGL G PG+ G PG KG +G G P Sbjct: 976 GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFP 1035 Query: 663 GFPGL---PGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPG-------PV 712 G G+ PG G+ G G G G +G+KGDPG +G PGLPGP G PG P Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPG 1095 Query: 713 VYVSEQDGSVLSVPGPEGR------PGFAGFPGPAGPK---------------GNLGSKG 751 + S D + +PG G PGF G PGP GPK G +G G Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155 Query: 752 ERGSPGPKGEKGEPGSIFSPDGGALGPA-QKGAKGEPGFRGPPGPYGRPGYKGEIGFPGR 810 G PGP GEKG+PG G GPA QKG G+PGF G PGP G PG G+ G G Sbjct: 1156 HPGQPGPPGEKGKPG-----QDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGL 1209 Query: 811 PGRPGMNGLKGEKGEPGDASLGF-GMRGMPGPPGPPGP--------PGPPGTPVYDSNVF 861 PG PG GL G KGEPG GF G++G PGPPG PGP PGP G P Sbjct: 1210 PGIPGNPGLPGPKGEPG--FHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPP------- 1260 Query: 862 AESSRPGPPGLPGNQGPP------GPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDR 915 RPG GLPG +GPP G KG KG G PG PG Q ++G G Sbjct: 1261 ---GRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRP 1317 Query: 916 GDAGQKGERGEPGGGGFFG----SSLPGPPGPP------GPRGYPGIPGPKGES--IRGQ 963 G G KG+ G PG GF G S +PG GP GP G PG+PGP G+S I+G Sbjct: 1318 GLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGD 1377 Query: 964 PGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPH--------------------RQT 1002 GPPG G PG+ G G QGP G PGP GPP PG + T Sbjct: 1378 AGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGT 1437 Query: 1003 ISVPGPPGP---PGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYV 1059 + GPPGP GPPGPPGT + G + TR + + P+G L LYV Sbjct: 1438 RGLDGPPGPDGLQGPPGPPGTSSVAHGFLI--TRHSQTTDAPQCPQGTLQVYEGFSLLYV 1495 Query: 1060 R 1060 + Sbjct: 1496 Q 1496 Score = 535 bits (1377), Expect = e-151 Identities = 365/926 (39%), Positives = 421/926 (45%), Gaps = 193/926 (20%) Query: 243 DSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQ 302 D G G+ G R G P LP P PP G +D + Sbjct: 39 DCSGIKGEKGE---------RGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPK 89 Query: 303 TTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSP 360 G PG+ + G PG + G G KG++G PG PG PG GPPG P Sbjct: 90 GIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPP 149 Query: 361 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGP---PGPPGRDGTPGRDGEPGDPGEDGKPG 417 +PG G P + + ++PGP+G PGPPG G PG G PG G G PG Sbjct: 150 GIPGMKGEPGSI--------IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPG 201 Query: 418 DTGPQGFPGTPGD--------VGPKGDKGDPGV--------------------------- 442 GP G PG PG GPKG+KG+ G+ Sbjct: 202 LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261 Query: 443 --GERGPPGP---QGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPG 497 G+RGPPGP +GPPGPPG + +K +G G G PG PG PG Sbjct: 262 LPGDRGPPGPPGIRGPPGPPGGE-KGEK----GEQGEPGKRGKPGKDGENGQPGIPGLPG 316 Query: 498 VPGLPGEPGRFG----VNSSDVPGP-------------------AGLPGVPGREGPPGFP 534 PG PGEPGR G + PGP GLPG+PG +G GFP Sbjct: 317 DPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFP 376 Query: 535 GLPGPPGPP--------GREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAG 586 G+ GPPG P G GPPG G++G G+ G PG G PG G G GL G Sbjct: 377 GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPG-ISIPGPPGLDGQPGAPGLPG 435 Query: 587 APGPAGP----------PGPPGPPGPPGPGLPAGFDDMEGSGGP--FWSTARSADGPQGP 634 PGPAGP PGPPGPPG PG G ++G G F GP G Sbjct: 436 PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495 Query: 635 PGLPGLKGDPGVPGLPGAKGE------VGADGVPGFPGLPGREGIAGPQGPKGD------ 682 PGLPGL G PG G PG KGE G G+PG PG PG G G +G GD Sbjct: 496 PGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG 555 Query: 683 -RGSRGEKGDPGKDGV----------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGR 731 +G +GE G PG G+ G PGLPGP G PG + + E+ GP G Sbjct: 556 MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGER--------GPPGN 607 Query: 732 PGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFR- 790 PG G PG GP G G G PGP GEKG G +P P G KG+PG Sbjct: 608 PGLPGLPGNIGPMGPPGF----GPPGPVGEKGIQGVAGNPG----QPGIPGPKGDPGQTI 659 Query: 791 ---GPPGPYGRPGYKGEIGF---PGRPGRPGMNGLKGEKGEPGDASLGF-------GMRG 837 G PG G PG G++G PG PG+PG+ G+ G KGEPG +G G G Sbjct: 660 TQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPG 719 Query: 838 MPGPPGPP---------GPPGPPGTPVYDSNV-FAESSRPGPPGLPGNQGPPGPKGAKGE 887 +PGPPG P GPPGPPG P FA PGPPGLPG +G GPKG +G Sbjct: 720 IPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF 779 Query: 888 VGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPR 947 GPPGPPG+ D L G KGD G GQ G G PG G PGPPG PGP Sbjct: 780 PGPPGPPGRTGLDGL------PGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPI 833 Query: 948 GYPGIPGPKGESIRGQPGPPG--PQGPPG-IGYEGRQGPPGPPGPPGPPSFPGP------ 998 G PG+ G GE +G PGPPG GPPG G G G PGP GPPG P PG Sbjct: 834 GQPGLHGIPGE--KGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGF 891 Query: 999 --HRQTISVPGPPGPPGPPGPPGTMG 1022 + + + GPPGPPGP G PG G Sbjct: 892 PGTKGEMGMMGPPGPPGPLGIPGRSG 917 Score = 528 bits (1360), Expect = e-149 Identities = 344/783 (43%), Positives = 387/783 (49%), Gaps = 131/783 (16%) Query: 328 TPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPG 387 +PG + G+KG+KGE G PG G G PG P GPPG G GP PG Sbjct: 33 SPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGP-----PG 87 Query: 388 PQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGP 447 P+G GPPG G PG G PG PG DG P GPQG PG G G +G G PG Sbjct: 88 PKGIRGPPGLPGFPGTPGLPGMPGHDGAP---GPQGIPGCNGTKGERGFPGSPGF----- 139 Query: 448 PGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGR 507 PG QGPPGPPG M+G + +L GP+G PG PGPPG+ GLPG G Sbjct: 140 PGLQGPPGPPG---------IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTG- 189 Query: 508 FGVNSSDVPGPAGLPGVPGREGPPGFPGLPGP--------------PGPPGREGPPGRTG 553 +PGP G PG PG GPPG PGLPGP G G +GPPG G Sbjct: 190 -------IPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPG 242 Query: 554 Q----------------KGSLGEAGAPGHKGSKGAPG-PAGARGESGLAGAPGPAGPPGP 596 Q +G G+ G PG G +G PG P G +GE G G PG G PG Sbjct: 243 QISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGK 302 Query: 597 PGPPGPPG-PGLPAGFDDMEGSGGPFWSTARSAD-GPQGPPGLP----------GLKGDP 644 G G PG PGLP G G G + D GP GPPGL G KG+ Sbjct: 303 DGENGQPGIPGLP-GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNI 361 Query: 645 GVPGLPGAKGEVGADGVPGFPGLPGREGIA--GPQGPKGDRGSRGEKGDPGKDGV----- 697 G+PGLPG KGE G G+ G PGLPG G A GP GP G G RG+KGD G G+ Sbjct: 362 GLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP 421 Query: 698 -------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSK 750 G PGLPGPPGP GP + S++ + PGP G PG G G G +G G K Sbjct: 422 PGLDGQPGAPGLPGPPGPAGPHIPPSDE----ICEPGPPGPPGSPGDKGLQGEQGVKGDK 477 Query: 751 GE-------RGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKG 803 G+ G GP G+ G PG + P G P QKG KG+ G GP G G PG G Sbjct: 478 GDTCFNCIGTGISGPPGQPGLPG-LPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPG 536 Query: 804 EIGFPGRPGR-------PGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTP-- 854 GFPG G PGM G KGE G PG L G+ G PG G PG PGP G P Sbjct: 537 APGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP-GLPGTPGQDGLPGLPGPKGEPGG 595 Query: 855 VYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGD 914 + PG PGLPGN GP GP G GPPGP G+ + G G Sbjct: 596 ITFKGERGPPGNPGLPGLPGNIGPMGPPG----FGPPGPVGEKGIQGVAGNPGQPGIPGP 651 Query: 915 RGDAG----QKGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIPGPKGE---SIRGQPGP 966 +GD G Q G+ G PG G G LPG PG PG G PGIPG KGE G PGP Sbjct: 652 KGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP 711 Query: 967 PGPQGPPGIGYEGRQGPPGPP------GPPGPPSFPGPHRQT-ISVPGPPGPPGPPGPPG 1019 PGP+G PGI G G PG P GPPGPP FPGP + ++PGPPGPPG PG G Sbjct: 712 PGPKGFPGI--PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG 769 Query: 1020 TMG 1022 +G Sbjct: 770 ALG 772 Score = 437 bits (1125), Expect = e-122 Identities = 275/644 (42%), Positives = 317/644 (49%), Gaps = 84/644 (13%) Query: 314 PGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPG--------- 364 PG + G PG V G G++G PG+PG PG GPPGSP LPG Sbjct: 836 PGLHGIPGEKGDPGPPGLDVP--GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPG 893 Query: 365 ---------PPGLPCPVSPLGPAG-PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDG 414 PPG P P+ G +G P L+ G QG PG PG G G GEPG PG G Sbjct: 894 TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG 953 Query: 415 --------KPGDTGPQGFPGTPGDVGPKGDKGDPG----VGERGPPGPQGPPGPPGPSFR 462 G+ G G PG PG GPKG +G PG G G PG GPPGP G Sbjct: 954 PMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGL 1013 Query: 463 HDKLTFIDMEG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPA-- 519 + I G G GD+ GP+G GPPGP GVPG PG PG G D P Sbjct: 1014 PGQPGLIGPPGLKGTIGDM-GFPGPQGVEGPPGPSGVPGQPGSPGLPG-QKGDKGDPGIS 1071 Query: 520 --GLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAG 577 GLPG+PG +G PG PG PG PG G G PG G G+ G G PG G G PGP G Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131 Query: 578 ARGESGLAGAPGPAGPPGP------PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGP 631 +G SG G PG G PGP PG PGPPG G D + G G + G Sbjct: 1132 PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGN 1191 Query: 632 QGPPGLPGL---KGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGP-----KGDR 683 GPPGLPGL KGD G+PG+PG G G G PGF G PG +G GP G +G + Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251 Query: 684 GSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGP 743 G+ G +G PG+ G GLPGP GPPG +G + G G+PG G PG G Sbjct: 1252 GNPGPQGPPGRPGF--QGLPGPEGPPG-----LPGNGGIKGEKGNPGQPGLPGLPGLKGD 1304 Query: 744 KGNLGSKGERGSPGPKGEKGEPGSIFSP-----DGGALGPAQKGAKGEPGFRGPPGPYGR 798 +G G +G G PG G KG+PG P G + P G +GEPG GPPGP G Sbjct: 1305 QGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGL 1364 Query: 799 PG-------YKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPP 851 PG KG+ G PG PG+PG+ GL G +G +G+PGP GPPG PG Sbjct: 1365 PGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGP----------QGLPGPTGPPGDPGRN 1414 Query: 852 GTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPG 895 G P +D PG PG PG +G GP G G GPPGPPG Sbjct: 1415 GLPGFD-GAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1457 Score = 398 bits (1022), Expect = e-110 Identities = 267/677 (39%), Positives = 316/677 (46%), Gaps = 147/677 (21%) Query: 425 PGTPGDV-GPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEAL 483 PG+ D G KG+KG ERG PG +G PG PG Sbjct: 34 PGSKCDCSGIKGEKG-----ERGFPGLEGHPGLPG------------------------F 64 Query: 484 RGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP 543 GP G PGP G G G+PG PG G+ GP GLPG PG PG PG+PG G P Sbjct: 65 PGPEGPPGPRGQKGDDGIPGPPGPKGIR-----GPPGLPGFPGT---PGLPGMPGHDGAP 116 Query: 544 GREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGA------PGPAGPPGPP 597 G +G PG G KG G G+PG G +G PGP G G G G+ PGP G PG P Sbjct: 117 GPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYP 176 Query: 598 GPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVG 657 GPPG G P G GP GPPG PGL G PG PGLPG KG +G Sbjct: 177 GPPGIQGLPGPTGIP-----------------GPIGPPGPPGLMGPPGPPGLPGPKGNMG 219 Query: 658 ADGVPGFPGLPGREGIAGPQGP----------------KGDRGSRGEKGDPGKDGVGQPG 701 + G G G +G+ GP GP KGD+G G++G PG PG Sbjct: 220 LN-FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP-----PG 273 Query: 702 LPGPPGPPGPVVYVSEQDGSV-----LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSP 756 + GPPGPPG + G G G+PG G PG G G G GE+G Sbjct: 274 IRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQK 333 Query: 757 GPKGEKGEPGSIFSPDG--------GALG----PAQKGAKGEPGFRGPPGPYGRPGYKGE 804 G G G PG + G G +G P +KG +G PG +GPPG G PG Sbjct: 334 GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG-AAV 392 Query: 805 IGFPGRPGRPGMNGLKGEKGEPGDASLGF-GMRGMPGPPGPPGPPGPPGTPVYDSNVFAE 863 +G PG PG PG G KG++G PG + G G+ G PG PG PGPPGP G + S+ E Sbjct: 393 MGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICE 452 Query: 864 SSRPGPPGLPGNQGPPGPKGAKGEVG-------------PPGPPGQFPFDFLQLEAEMKG 910 PGPPG PG++G G +G KG+ G PPG PG G Sbjct: 453 PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512 Query: 911 EKGDRGDAGQKGERG------EPGGGGFFGS--------SLPGPPGP------PGPRGYP 950 +KG++G AG G +G PG GF GS + PG G PG G P Sbjct: 513 QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572 Query: 951 GIPGPKGESIRGQPGPPGPQGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPP 1009 G+PG G+ G PG PGP+G PG I ++G +GPPG PG PG P GP GPP Sbjct: 573 GLPGTPGQD--GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPM-------GPP 623 Query: 1010 G--PPGPPGPPGTMGAS 1024 G PPGP G G G + Sbjct: 624 GFGPPGPVGEKGIQGVA 640 Score = 394 bits (1011), Expect = e-109 Identities = 259/615 (42%), Positives = 294/615 (47%), Gaps = 121/615 (19%) Query: 265 ETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDG 324 E G+ +P LP PP P L G S+ E+ E G +PG + G Sbjct: 939 EKGSKGEPGLPGPPGPMDPNLLG------SKGEKGEP-------GLPGIPGVSGPKGYQG 985 Query: 325 SVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP-ALQ 383 PG + GL GQ G PG PGP G G PG P L GPPGL + +G GP ++ Sbjct: 986 LPGDPG----QPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVE 1041 Query: 384 TVPGPQGPPGPPGRDGTPGRDGEPGDPGED-----GKPGDTGPQGFPGTPGDVGPKGDKG 438 PGP G PG PG G PG+ G+ GDPG G PG G G PG PG+ G KG G Sbjct: 1042 GPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVG 1101 Query: 439 DPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPG 491 DPG+ G +G PG G PG PGP GP+G G Sbjct: 1102 DPGLPGLPGTPGAKGQPGLPGFPGTPGPP------------------------GPKGISG 1137 Query: 492 PPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP--GREGPP 549 PPG PG+PG PG G G PGP G G PG++G PG G G PG P G GPP Sbjct: 1138 PPGNPGLPGEPGPVG--GGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPP 1195 Query: 550 GRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPA 609 G G G G+ G PG G+ G PGP +GE G G PG GPPGPPG PGP Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGP---KGEPGFHGFPGVQGPPGPPGSPGPA------ 1246 Query: 610 GFDDMEGSGGPFWSTARSADGPQGPP------GLPGLKGDPGVPGLPGAKGEVGADGVPG 663 +EG G GPQGPP GLPG +G PG+PG G KGE G G PG Sbjct: 1247 ----LEGPKG--------NPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPG 1294 Query: 664 FPGLPGREGIAGP---QGPKGDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQD 719 PGLPG +G GP QG G G G KGDPG GV G PG+ GP G PG Sbjct: 1295 LPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSA------- 1347 Query: 720 GSVLSVPGPEGRPGFAGFPGPAGPKGNLG-SKGERGSPGPKGEKGEPGSIFSPDGGALGP 778 GPEG PG G PGP G G G S +G GP G G+PG G GP Sbjct: 1348 -------GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGL-----KGLPGP 1395 Query: 779 AQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGM 838 +G +G PG GPPG GR G G G GR G PG+ G G +G + G Sbjct: 1396 --QGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRG----------LDGP 1443 Query: 839 PGPPGPPGPPGPPGT 853 PGP G GPPGPPGT Sbjct: 1444 PGPDGLQGPPGPPGT 1458 Score = 386 bits (992), Expect = e-107 Identities = 260/666 (39%), Positives = 299/666 (44%), Gaps = 151/666 (22%) Query: 500 GLPGEPGR-FGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSL 558 G P E +G + +G+ G G G PG G PG PG PG EGPPG GQKG Sbjct: 21 GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80 Query: 559 GEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSG 618 G G PG KG +G PG G G GL G PG G PGP G PG G GF G Sbjct: 81 GIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP 140 Query: 619 GPFWSTARSADGPQGPPGLPGLKGDPG---VPGLPGAKGEVGADGVPGFPGLPGREGIAG 675 G GP GPPG+PG+KG+PG + LPG KG G G PG GLPG GI G Sbjct: 141 G--------LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPG 192 Query: 676 PQGPKGDRGSRGEKGDPGKDG---------------VGQPGLPGPPGPPGPV-------- 712 P GP G G G G PG G G+ GL GPPGPPG + Sbjct: 193 PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252 Query: 713 VYVSEQDGSVLSVPGPEGRPGFAGFPGP----AGPKGNLGSKGERGSPGPKGEKGEPGSI 768 V + D + GP G PG G PGP G KG G G+RG PG GE G+PG Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312 Query: 769 FSP-DGGALG-PAQKGAKGEPGFRGPPGP----------------------YGRPGYKGE 804 P D G G P + G KG+ G GPPGP G PG KGE Sbjct: 313 GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372 Query: 805 IGFP-----------------GRPGRPGMNGLKGEKGEPGDASLGF----GMRGMPGPPG 843 GFP G PG PG G +G+KG+ G + G+ G PG PG Sbjct: 373 RGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPG 432 Query: 844 PPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE-------------VGP 890 PGPPGP G + S+ E PGPPG PG++G G +G KG+ GP Sbjct: 433 LPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGP 492 Query: 891 PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGER------GEPGGGGFFGS--------- 935 PG PG G+KG++G AG G + G PG GF GS Sbjct: 493 PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT 552 Query: 936 -----------------SLPGPPGPPGPRGYPGIPGPKGE----SIRGQPGPPGPQGPPG 974 LPG PG PG G PG+PGPKGE + +G+ GPPG G PG Sbjct: 553 FPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPG 612 Query: 975 I-GYEGRQGPP--GPPGP------------PGPPSFPGPH---RQTISVPGPPGPPGPPG 1016 + G G GPP GPPGP PG P PGP QTI+ PG PG PG PG Sbjct: 613 LPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPG 672 Query: 1017 PPGTMG 1022 G +G Sbjct: 673 RDGDVG 678 Score = 243 bits (621), Expect = 7e-64 Identities = 158/371 (42%), Positives = 183/371 (49%), Gaps = 63/371 (16%) Query: 681 GDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGP 740 G +G +GE+G PG +G PGLPG PGP GP PGP G+ G G PGP Sbjct: 42 GIKGEKGERGFPGLEG--HPGLPGFPGPEGP--------------PGPRGQKGDDGIPGP 85 Query: 741 AGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPG 800 GPKG G G G PG G G PG +P + P G KGE GF G PG G G Sbjct: 86 PGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGI-PGCNGTKGERGFPGSPGFPGLQG 144 Query: 801 YKGEIGFPGRPGRPG---MNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYD 857 G G PG G PG M+ L G KG PG G++G+PGP G PGP GPPG P Sbjct: 145 PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPP-GIQGLPGPTGIPGPIGPPGPP--- 200 Query: 858 SNVFAESSRPGPPGLPGN--------QGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMK 909 PGPPGLPG QGP G KG +G GPPGPPGQ ++ E Sbjct: 201 ----GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEF- 255 Query: 910 GEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPG-PKGESIRGQPGPPG 968 QKG++G PG G PPGPPG RG PG PG KGE +G+ G PG Sbjct: 256 ----------QKGDQGLPGDRG--------PPGPPGIRGPPGPPGGEKGE--KGEQGEPG 295 Query: 969 PQGPPGIGYEGRQGPPGPPGPPGPPSFPG-PHRQTISVPGPPGPPGPPGPPGTMGASSGV 1027 +G PG +G G PG PG PG P +PG P R G G GPPGPPG + G Sbjct: 296 KRGKPG--KDGENGQPGIPGLPGDPGYPGEPGRD--GEKGQKGDTGPPGPPGLVIPRPGT 351 Query: 1028 RLWATRQAMLG 1038 + + +G Sbjct: 352 GITIGEKGNIG 362 Score = 157 bits (398), Expect = 5e-38 Identities = 119/323 (36%), Positives = 142/323 (43%), Gaps = 43/323 (13%) Query: 817 NGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQ 876 +G+KGEKGE G L G G+PG PGP GPPGP G + PGPPG G + Sbjct: 41 SGIKGEKGERGFPGLE-GHPGLPGFPGPEGPPGPRGQK-------GDDGIPGPPGPKGIR 92 Query: 877 GPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSS 936 GPPG G G G PG PG G +G G G KGERG PG GF Sbjct: 93 GPPGLPGFPGTPGLPGMPGH---------DGAPGPQGIPGCNGTKGERGFPGSPGF---- 139 Query: 937 LPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFP 996 PG GPPGP G PG+ G G I PGP+G PG GPPG G PGP P Sbjct: 140 -PGLQGPPGPPGIPGMKGEPGSIIMSSL--PGPKGNPGY-----PGPPGIQGLPGPTGIP 191 Query: 997 GPHRQTISVPGPPGPPGPPGPPGTMG--ASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQ 1054 GP I PGPPG GPPGPPG G + G+ + Q + P G ++EQ Sbjct: 192 GP----IGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQ 247 Query: 1055 EE-LYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPW 1113 + + V Q G + P RG PP + + P +P Sbjct: 248 KRPIDVEFQKG------DQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPG 301 Query: 1114 R-ADDILASPPRLPEPQPYPGAP 1135 + ++ P LP YPG P Sbjct: 302 KDGENGQPGIPGLPGDPGYPGEP 324 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 540 bits (1391), Expect = e-153 Identities = 374/904 (41%), Positives = 426/904 (47%), Gaps = 197/904 (21%) Query: 315 GSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGP---PGSPCLPGPPGLP-C 370 G V+ G PG + G Q G+PG+PG PGR G PG P LPG PGLP Sbjct: 635 GIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGI 694 Query: 371 PVSPLGPAGPA--LQTVPGPQGP---PGPPGRDGTPGR---DGEPGDPGEDGK------- 415 P S P P L PGP+G PGPPG GTPGR +G PG PG G Sbjct: 695 PGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFA 754 Query: 416 -PGDTGPQGFPGTPGDVGPKGDKGDPG-------------------VGERGPPGPQGPPG 455 PG GP G PG G +GPKGD+G PG VG G PGP GPPG Sbjct: 755 LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPG 814 Query: 456 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 515 PG I ++G GP G PGP G PG+ G+PGE G G DV Sbjct: 815 LPG----------IGVQGP---------PGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV 855 Query: 516 PGP------AGLPGVPGREGPPGFPGLP------------------GPPGPPGREGPPGR 551 PGP G+PG PG GPPG PGLP GPPGPPG G PGR Sbjct: 856 PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915 Query: 552 TGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGP--------PGPPGPPGPP 603 +G G G+ G G G G G G++GE GL G PGP P G PG PG P Sbjct: 916 SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975 Query: 604 GPGLPAGFDDMEGS-GGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVP 662 G P G+ + G G P S GP GP G PGL G PG+ G PG KG +G G P Sbjct: 976 GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFP 1035 Query: 663 GFPGL---PGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPG-------PV 712 G G+ PG G+ G G G G +G+KGDPG +G PGLPGP G PG P Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPG 1095 Query: 713 VYVSEQDGSVLSVPGPEGR------PGFAGFPGPAGPK---------------GNLGSKG 751 + S D + +PG G PGF G PGP GPK G +G G Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155 Query: 752 ERGSPGPKGEKGEPGSIFSPDGGALGPA-QKGAKGEPGFRGPPGPYGRPGYKGEIGFPGR 810 G PGP GEKG+PG G GPA QKG G+PGF G PGP G PG G+ G G Sbjct: 1156 HPGQPGPPGEKGKPG-----QDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGL 1209 Query: 811 PGRPGMNGLKGEKGEPGDASLGF-GMRGMPGPPGPPGP--------PGPPGTPVYDSNVF 861 PG PG GL G KGEPG GF G++G PGPPG PGP PGP G P Sbjct: 1210 PGIPGNPGLPGPKGEPG--FHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPP------- 1260 Query: 862 AESSRPGP---PGLPGNQGPP------GPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEK 912 RPGP GLPG +GPP G KG KG G PG PG Q ++G Sbjct: 1261 ---GRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNP 1317 Query: 913 GDRGDAGQKGERGEPGGGGFFG----SSLPGPPGPP------GPRGYPGIPGPKGES--I 960 G G G KG+ G PG GF G S +PG GP GP G PG+PGP G+S I Sbjct: 1318 GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIII 1377 Query: 961 RGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPH-------------------- 999 +G GPPG G PG+ G G QGP G PGP GPP PG + Sbjct: 1378 KGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQ 1437 Query: 1000 RQTISVPGPPGP---PGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEE 1056 T + GPPGP GPPGPPGT + G + TR + + P+G L Sbjct: 1438 PGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLI--TRHSQTTDAPQCPQGTLQVYEGFSL 1495 Query: 1057 LYVR 1060 LYV+ Sbjct: 1496 LYVQ 1499 Score = 535 bits (1377), Expect = e-151 Identities = 365/926 (39%), Positives = 421/926 (45%), Gaps = 193/926 (20%) Query: 243 DSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQ 302 D G G+ G R G P LP P PP G +D + Sbjct: 39 DCSGIKGEKGE---------RGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPK 89 Query: 303 TTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSP 360 G PG+ + G PG + G G KG++G PG PG PG GPPG P Sbjct: 90 GIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPP 149 Query: 361 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGP---PGPPGRDGTPGRDGEPGDPGEDGKPG 417 +PG G P + + ++PGP+G PGPPG G PG G PG G G PG Sbjct: 150 GIPGMKGEPGSI--------IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPG 201 Query: 418 DTGPQGFPGTPGD--------VGPKGDKGDPGV--------------------------- 442 GP G PG PG GPKG+KG+ G+ Sbjct: 202 LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261 Query: 443 --GERGPPGP---QGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPG 497 G+RGPPGP +GPPGPPG + +K +G G G PG PG PG Sbjct: 262 LPGDRGPPGPPGIRGPPGPPGGE-KGEK----GEQGEPGKRGKPGKDGENGQPGIPGLPG 316 Query: 498 VPGLPGEPGRFG----VNSSDVPGP-------------------AGLPGVPGREGPPGFP 534 PG PGEPGR G + PGP GLPG+PG +G GFP Sbjct: 317 DPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFP 376 Query: 535 GLPGPPGPP--------GREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAG 586 G+ GPPG P G GPPG G++G G+ G PG G PG G G GL G Sbjct: 377 GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPG-ISIPGPPGLDGQPGAPGLPG 435 Query: 587 APGPAGP----------PGPPGPPGPPGPGLPAGFDDMEGSGGP--FWSTARSADGPQGP 634 PGPAGP PGPPGPPG PG G ++G G F GP G Sbjct: 436 PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495 Query: 635 PGLPGLKGDPGVPGLPGAKGE------VGADGVPGFPGLPGREGIAGPQGPKGD------ 682 PGLPGL G PG G PG KGE G G+PG PG PG G G +G GD Sbjct: 496 PGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG 555 Query: 683 -RGSRGEKGDPGKDGV----------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGR 731 +G +GE G PG G+ G PGLPGP G PG + + E+ GP G Sbjct: 556 MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGER--------GPPGN 607 Query: 732 PGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFR- 790 PG G PG GP G G G PGP GEKG G +P P G KG+PG Sbjct: 608 PGLPGLPGNIGPMGPPGF----GPPGPVGEKGIQGVAGNPG----QPGIPGPKGDPGQTI 659 Query: 791 ---GPPGPYGRPGYKGEIGF---PGRPGRPGMNGLKGEKGEPGDASLGF-------GMRG 837 G PG G PG G++G PG PG+PG+ G+ G KGEPG +G G G Sbjct: 660 TQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPG 719 Query: 838 MPGPPGPP---------GPPGPPGTPVYDSNV-FAESSRPGPPGLPGNQGPPGPKGAKGE 887 +PGPPG P GPPGPPG P FA PGPPGLPG +G GPKG +G Sbjct: 720 IPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF 779 Query: 888 VGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPR 947 GPPGPPG+ D L G KGD G GQ G G PG G PGPPG PGP Sbjct: 780 PGPPGPPGRTGLDGL------PGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPI 833 Query: 948 GYPGIPGPKGESIRGQPGPPG--PQGPPG-IGYEGRQGPPGPPGPPGPPSFPGP------ 998 G PG+ G GE +G PGPPG GPPG G G G PGP GPPG P PG Sbjct: 834 GQPGLHGIPGE--KGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGF 891 Query: 999 --HRQTISVPGPPGPPGPPGPPGTMG 1022 + + + GPPGPPGP G PG G Sbjct: 892 PGTKGEMGMMGPPGPPGPLGIPGRSG 917 Score = 528 bits (1360), Expect = e-149 Identities = 344/783 (43%), Positives = 387/783 (49%), Gaps = 131/783 (16%) Query: 328 TPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPG 387 +PG + G+KG+KGE G PG G G PG P GPPG G GP PG Sbjct: 33 SPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGP-----PG 87 Query: 388 PQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGP 447 P+G GPPG G PG G PG PG DG P GPQG PG G G +G G PG Sbjct: 88 PKGIRGPPGLPGFPGTPGLPGMPGHDGAP---GPQGIPGCNGTKGERGFPGSPGF----- 139 Query: 448 PGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGR 507 PG QGPPGPPG M+G + +L GP+G PG PGPPG+ GLPG G Sbjct: 140 PGLQGPPGPPG---------IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTG- 189 Query: 508 FGVNSSDVPGPAGLPGVPGREGPPGFPGLPGP--------------PGPPGREGPPGRTG 553 +PGP G PG PG GPPG PGLPGP G G +GPPG G Sbjct: 190 -------IPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPG 242 Query: 554 Q----------------KGSLGEAGAPGHKGSKGAPG-PAGARGESGLAGAPGPAGPPGP 596 Q +G G+ G PG G +G PG P G +GE G G PG G PG Sbjct: 243 QISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGK 302 Query: 597 PGPPGPPG-PGLPAGFDDMEGSGGPFWSTARSAD-GPQGPPGLP----------GLKGDP 644 G G PG PGLP G G G + D GP GPPGL G KG+ Sbjct: 303 DGENGQPGIPGLP-GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNI 361 Query: 645 GVPGLPGAKGEVGADGVPGFPGLPGREGIA--GPQGPKGDRGSRGEKGDPGKDGV----- 697 G+PGLPG KGE G G+ G PGLPG G A GP GP G G RG+KGD G G+ Sbjct: 362 GLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP 421 Query: 698 -------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSK 750 G PGLPGPPGP GP + S++ + PGP G PG G G G +G G K Sbjct: 422 PGLDGQPGAPGLPGPPGPAGPHIPPSDE----ICEPGPPGPPGSPGDKGLQGEQGVKGDK 477 Query: 751 GE-------RGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKG 803 G+ G GP G+ G PG + P G P QKG KG+ G GP G G PG G Sbjct: 478 GDTCFNCIGTGISGPPGQPGLPG-LPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPG 536 Query: 804 EIGFPGRPGR-------PGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTP-- 854 GFPG G PGM G KGE G PG L G+ G PG G PG PGP G P Sbjct: 537 APGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP-GLPGTPGQDGLPGLPGPKGEPGG 595 Query: 855 VYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGD 914 + PG PGLPGN GP GP G GPPGP G+ + G G Sbjct: 596 ITFKGERGPPGNPGLPGLPGNIGPMGPPG----FGPPGPVGEKGIQGVAGNPGQPGIPGP 651 Query: 915 RGDAG----QKGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIPGPKGE---SIRGQPGP 966 +GD G Q G+ G PG G G LPG PG PG G PGIPG KGE G PGP Sbjct: 652 KGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP 711 Query: 967 PGPQGPPGIGYEGRQGPPGPP------GPPGPPSFPGPHRQT-ISVPGPPGPPGPPGPPG 1019 PGP+G PGI G G PG P GPPGPP FPGP + ++PGPPGPPG PG G Sbjct: 712 PGPKGFPGI--PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG 769 Query: 1020 TMG 1022 +G Sbjct: 770 ALG 772 Score = 440 bits (1131), Expect = e-123 Identities = 278/647 (42%), Positives = 315/647 (48%), Gaps = 87/647 (13%) Query: 314 PGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPG--------- 364 PG + G PG V G G++G PG+PG PG GPPGSP LPG Sbjct: 836 PGLHGIPGEKGDPGPPGLDVP--GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPG 893 Query: 365 ---------PPGLPCPVSPLGPAG-PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDG 414 PPG P P+ G +G P L+ G QG PG PG G G GEPG PG G Sbjct: 894 TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG 953 Query: 415 --------KPGDTGPQGFPGTPGDVGPKGDKGDPG----VGERGPPGPQGPPGPPGPSFR 462 G+ G G PG PG GPKG +G PG G G PG GPPGP G Sbjct: 954 PMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGL 1013 Query: 463 HDKLTFIDMEG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPA-- 519 + I G G GD+ GP+G GPPGP GVPG PG PG G D P Sbjct: 1014 PGQPGLIGPPGLKGTIGDM-GFPGPQGVEGPPGPSGVPGQPGSPGLPG-QKGDKGDPGIS 1071 Query: 520 --GLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAG 577 GLPG+PG +G PG PG PG PG G G PG G G+ G G PG G G PGP G Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131 Query: 578 ARGESGLAGAPGPAGPPGP------PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGP 631 +G SG G PG G PGP PG PGPPG G D + G G + G Sbjct: 1132 PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGN 1191 Query: 632 QGPPGLPGLKGD---------PGVPGLPGAKGEVGADGVPGFPGLPGREGIAGP--QGPK 680 GPPGLPGL G PG PGLPG KGE G G PG G PG G GP +GPK Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251 Query: 681 GDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGP 740 G+ G +G G PG G GLPGP GPPG +G + G G+PG G PG Sbjct: 1252 GNPGPQGPPGRPGPTGF--QGLPGPEGPPG-----LPGNGGIKGEKGNPGQPGLPGLPGL 1304 Query: 741 AGPKGNLGSKGERGSPGPKGEKGEPGSIFSP-----DGGALGPAQKGAKGEPGFRGPPGP 795 G +G G +G G PG G KG+PG P G + P G +GEPG GPPGP Sbjct: 1305 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1364 Query: 796 YGRPG-------YKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPP 848 G PG KG+ G PG PG+PG+ GL G +G +G+PGP GPPG P Sbjct: 1365 PGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGP----------QGLPGPTGPPGDP 1414 Query: 849 GPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPG 895 G G P +D PG PG PG +G GP G G GPPGPPG Sbjct: 1415 GRNGLPGFD-GAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460 Score = 398 bits (1022), Expect = e-110 Identities = 267/677 (39%), Positives = 316/677 (46%), Gaps = 147/677 (21%) Query: 425 PGTPGDV-GPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEAL 483 PG+ D G KG+KG ERG PG +G PG PG Sbjct: 34 PGSKCDCSGIKGEKG-----ERGFPGLEGHPGLPG------------------------F 64 Query: 484 RGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP 543 GP G PGP G G G+PG PG G+ GP GLPG PG PG PG+PG G P Sbjct: 65 PGPEGPPGPRGQKGDDGIPGPPGPKGIR-----GPPGLPGFPGT---PGLPGMPGHDGAP 116 Query: 544 GREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGA------PGPAGPPGPP 597 G +G PG G KG G G+PG G +G PGP G G G G+ PGP G PG P Sbjct: 117 GPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYP 176 Query: 598 GPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVG 657 GPPG G P G GP GPPG PGL G PG PGLPG KG +G Sbjct: 177 GPPGIQGLPGPTGIP-----------------GPIGPPGPPGLMGPPGPPGLPGPKGNMG 219 Query: 658 ADGVPGFPGLPGREGIAGPQGP----------------KGDRGSRGEKGDPGKDGVGQPG 701 + G G G +G+ GP GP KGD+G G++G PG PG Sbjct: 220 LN-FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP-----PG 273 Query: 702 LPGPPGPPGPVVYVSEQDGSV-----LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSP 756 + GPPGPPG + G G G+PG G PG G G G GE+G Sbjct: 274 IRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQK 333 Query: 757 GPKGEKGEPGSIFSPDG--------GALG----PAQKGAKGEPGFRGPPGPYGRPGYKGE 804 G G G PG + G G +G P +KG +G PG +GPPG G PG Sbjct: 334 GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG-AAV 392 Query: 805 IGFPGRPGRPGMNGLKGEKGEPGDASLGF-GMRGMPGPPGPPGPPGPPGTPVYDSNVFAE 863 +G PG PG PG G KG++G PG + G G+ G PG PG PGPPGP G + S+ E Sbjct: 393 MGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICE 452 Query: 864 SSRPGPPGLPGNQGPPGPKGAKGEVG-------------PPGPPGQFPFDFLQLEAEMKG 910 PGPPG PG++G G +G KG+ G PPG PG G Sbjct: 453 PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512 Query: 911 EKGDRGDAGQKGERG------EPGGGGFFGS--------SLPGPPGP------PGPRGYP 950 +KG++G AG G +G PG GF GS + PG G PG G P Sbjct: 513 QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572 Query: 951 GIPGPKGESIRGQPGPPGPQGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPP 1009 G+PG G+ G PG PGP+G PG I ++G +GPPG PG PG P GP GPP Sbjct: 573 GLPGTPGQD--GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPM-------GPP 623 Query: 1010 G--PPGPPGPPGTMGAS 1024 G PPGP G G G + Sbjct: 624 GFGPPGPVGEKGIQGVA 640 Score = 397 bits (1019), Expect = e-110 Identities = 256/609 (42%), Positives = 291/609 (47%), Gaps = 106/609 (17%) Query: 265 ETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDG 324 E G+ +P LP PP P L G S+ E+ E G +PG + G Sbjct: 939 EKGSKGEPGLPGPPGPMDPNLLG------SKGEKGEP-------GLPGIPGVSGPKGYQG 985 Query: 325 SVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP-ALQ 383 PG + GL GQ G PG PGP G G PG P L GPPGL + +G GP ++ Sbjct: 986 LPGDPG----QPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVE 1041 Query: 384 TVPGPQGPPGPPGRDGTPGRDGEPGDPGED-----GKPGDTGPQGFPGTPGDVGPKGDKG 438 PGP G PG PG G PG+ G+ GDPG G PG G G PG PG+ G KG G Sbjct: 1042 GPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVG 1101 Query: 439 DPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPG 491 DPG+ G +G PG G PG PGP GP+G G Sbjct: 1102 DPGLPGLPGTPGAKGQPGLPGFPGTPGPP------------------------GPKGISG 1137 Query: 492 PPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP--GREGPP 549 PPG PG+PG PG G G PGP G G PG++G PG G G PG P G GPP Sbjct: 1138 PPGNPGLPGEPGPVG--GGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPP 1195 Query: 550 GRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPA 609 G G G G+ G PG G+ G PGP +GE G G PG GPPGPPG PGP Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGP---KGEPGFHGFPGVQGPPGPPGSPGP------- 1245 Query: 610 GFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPG 669 + +G+ GP R GP G GLPG +G PG+PG G KGE G G PG PGLPG Sbjct: 1246 ALEGPKGNPGPQGPPGR--PGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPG 1303 Query: 670 REGIAGP---QGPKGDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSV 725 +G GP QG G G G KGDPG GV G PG+ GP G PG Sbjct: 1304 LKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSA------------- 1350 Query: 726 PGPEGRPGFAGFPGPAGPKGNLG-SKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAK 784 GPEG PG G PGP G G G S +G GP G G+PG KG Sbjct: 1351 -GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPG-------------LKGLP 1396 Query: 785 GEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGP 844 G G +G PGP G PG G G PG G G G G G+PG G+ G PGP G Sbjct: 1397 GPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTR----GLDGPPGPDGL 1452 Query: 845 PGPPGPPGT 853 GPPGPPGT Sbjct: 1453 QGPPGPPGT 1461 Score = 386 bits (992), Expect = e-107 Identities = 260/666 (39%), Positives = 299/666 (44%), Gaps = 151/666 (22%) Query: 500 GLPGEPGR-FGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSL 558 G P E +G + +G+ G G G PG G PG PG PG EGPPG GQKG Sbjct: 21 GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80 Query: 559 GEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSG 618 G G PG KG +G PG G G GL G PG G PGP G PG G GF G Sbjct: 81 GIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP 140 Query: 619 GPFWSTARSADGPQGPPGLPGLKGDPG---VPGLPGAKGEVGADGVPGFPGLPGREGIAG 675 G GP GPPG+PG+KG+PG + LPG KG G G PG GLPG GI G Sbjct: 141 G--------LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPG 192 Query: 676 PQGPKGDRGSRGEKGDPGKDG---------------VGQPGLPGPPGPPGPV-------- 712 P GP G G G G PG G G+ GL GPPGPPG + Sbjct: 193 PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252 Query: 713 VYVSEQDGSVLSVPGPEGRPGFAGFPGP----AGPKGNLGSKGERGSPGPKGEKGEPGSI 768 V + D + GP G PG G PGP G KG G G+RG PG GE G+PG Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312 Query: 769 FSP-DGGALG-PAQKGAKGEPGFRGPPGP----------------------YGRPGYKGE 804 P D G G P + G KG+ G GPPGP G PG KGE Sbjct: 313 GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372 Query: 805 IGFP-----------------GRPGRPGMNGLKGEKGEPGDASLGF----GMRGMPGPPG 843 GFP G PG PG G +G+KG+ G + G+ G PG PG Sbjct: 373 RGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPG 432 Query: 844 PPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE-------------VGP 890 PGPPGP G + S+ E PGPPG PG++G G +G KG+ GP Sbjct: 433 LPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGP 492 Query: 891 PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGER------GEPGGGGFFGS--------- 935 PG PG G+KG++G AG G + G PG GF GS Sbjct: 493 PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT 552 Query: 936 -----------------SLPGPPGPPGPRGYPGIPGPKGE----SIRGQPGPPGPQGPPG 974 LPG PG PG G PG+PGPKGE + +G+ GPPG G PG Sbjct: 553 FPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPG 612 Query: 975 I-GYEGRQGPP--GPPGP------------PGPPSFPGPH---RQTISVPGPPGPPGPPG 1016 + G G GPP GPPGP PG P PGP QTI+ PG PG PG PG Sbjct: 613 LPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPG 672 Query: 1017 PPGTMG 1022 G +G Sbjct: 673 RDGDVG 678 Score = 243 bits (621), Expect = 7e-64 Identities = 158/371 (42%), Positives = 183/371 (49%), Gaps = 63/371 (16%) Query: 681 GDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGP 740 G +G +GE+G PG +G PGLPG PGP GP PGP G+ G G PGP Sbjct: 42 GIKGEKGERGFPGLEG--HPGLPGFPGPEGP--------------PGPRGQKGDDGIPGP 85 Query: 741 AGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPG 800 GPKG G G G PG G G PG +P + P G KGE GF G PG G G Sbjct: 86 PGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGI-PGCNGTKGERGFPGSPGFPGLQG 144 Query: 801 YKGEIGFPGRPGRPG---MNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYD 857 G G PG G PG M+ L G KG PG G++G+PGP G PGP GPPG P Sbjct: 145 PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPP-GIQGLPGPTGIPGPIGPPGPP--- 200 Query: 858 SNVFAESSRPGPPGLPGN--------QGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMK 909 PGPPGLPG QGP G KG +G GPPGPPGQ ++ E Sbjct: 201 ----GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEF- 255 Query: 910 GEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPG-PKGESIRGQPGPPG 968 QKG++G PG G PPGPPG RG PG PG KGE +G+ G PG Sbjct: 256 ----------QKGDQGLPGDRG--------PPGPPGIRGPPGPPGGEKGE--KGEQGEPG 295 Query: 969 PQGPPGIGYEGRQGPPGPPGPPGPPSFPG-PHRQTISVPGPPGPPGPPGPPGTMGASSGV 1027 +G PG +G G PG PG PG P +PG P R G G GPPGPPG + G Sbjct: 296 KRGKPG--KDGENGQPGIPGLPGDPGYPGEPGRD--GEKGQKGDTGPPGPPGLVIPRPGT 351 Query: 1028 RLWATRQAMLG 1038 + + +G Sbjct: 352 GITIGEKGNIG 362 Score = 157 bits (398), Expect = 5e-38 Identities = 119/323 (36%), Positives = 142/323 (43%), Gaps = 43/323 (13%) Query: 817 NGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQ 876 +G+KGEKGE G L G G+PG PGP GPPGP G + PGPPG G + Sbjct: 41 SGIKGEKGERGFPGLE-GHPGLPGFPGPEGPPGPRGQK-------GDDGIPGPPGPKGIR 92 Query: 877 GPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSS 936 GPPG G G G PG PG G +G G G KGERG PG GF Sbjct: 93 GPPGLPGFPGTPGLPGMPGH---------DGAPGPQGIPGCNGTKGERGFPGSPGF---- 139 Query: 937 LPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFP 996 PG GPPGP G PG+ G G I PGP+G PG GPPG G PGP P Sbjct: 140 -PGLQGPPGPPGIPGMKGEPGSIIMSSL--PGPKGNPGY-----PGPPGIQGLPGPTGIP 191 Query: 997 GPHRQTISVPGPPGPPGPPGPPGTMG--ASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQ 1054 GP I PGPPG GPPGPPG G + G+ + Q + P G ++EQ Sbjct: 192 GP----IGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQ 247 Query: 1055 EE-LYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPW 1113 + + V Q G + P RG PP + + P +P Sbjct: 248 KRPIDVEFQKG------DQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPG 301 Query: 1114 R-ADDILASPPRLPEPQPYPGAP 1135 + ++ P LP YPG P Sbjct: 302 KDGENGQPGIPGLPGDPGYPGEP 324 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 536 bits (1381), Expect = e-152 Identities = 362/868 (41%), Positives = 411/868 (47%), Gaps = 153/868 (17%) Query: 275 PAPPPVTTPPLAG----GSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPG 330 P PPP PP G G + S E+ + G LPG G V PG Sbjct: 452 PPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPG 511 Query: 331 GRVKEG---------GLKGQKGEPGVPGPPGRAGPPGSPCLPGP---PGLPCPVSPLGPA 378 + ++G G KG+KG G+PGPPGR G G PG PGLP V GP Sbjct: 512 PKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQ 571 Query: 379 GPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE------DGKPGDTGPQGFPGTPGDVG 432 GP +PGP G G PG G G G G+ GE GKPGDTG QG PG G G Sbjct: 572 GPP--GLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAG 629 Query: 433 PKGDKGD------PGV-----------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSG 475 P+G+KGD PGV GE+G PGP+G G PGP I EG Sbjct: 630 PQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGP---IGPEGRD 686 Query: 476 FGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPG 535 L+ LRG +G GPPG PG+ GL G PG GV PGP G PG+PG G PG PG Sbjct: 687 GPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGP--PGPGGSPGLPGEIGFPGKPG 744 Query: 536 LPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPG 595 PGP GPPG++GP G G G+ GE G G G G PG G GE GLAG PG G G Sbjct: 745 PPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAG 804 Query: 596 PPGPPGPPGPGLPAGFDDMEGS-GGPFWSTARSAD---GPQGPPGLPGLKG----DPGVP 647 PG PG PG G +G G P R GP GPPGLPG P +P Sbjct: 805 LPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMP 864 Query: 648 GLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPP 706 G G KGE G G+PG PGL GR G GPQGP G G++G++G G G G PG PG Sbjct: 865 GEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHV 924 Query: 707 GPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPG 766 G PGP PG G PG G PG G +G G+ GE GSPGP G +G+PG Sbjct: 925 GAPGP-----------SGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPG 973 Query: 767 SIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPG--------------------YKGEIG 806 + G GP KG GEPG RG PG G G KG+ G Sbjct: 974 A-----PGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRG 1028 Query: 807 FPGRPGRPGM--------------NGLKGEKGEPGDASL-GF-------GMRGMPGPPGP 844 PG PG PG +G G+KG PG L GF G G PG PG Sbjct: 1029 APGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGE 1088 Query: 845 PGPPGPPGTPVY----DSNVFAE----SSRPGPPGL------------PGNQGPPGPKGA 884 GPPG PG D N+ A+ PGPPGL PG G G +G Sbjct: 1089 RGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGK 1148 Query: 885 KGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPP 944 KGE GPPG PG + +GE+G G+ GQKG++G PG GF G PG PGPP Sbjct: 1149 KGEAGPPGLPGP---PGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGP--PGNPGPP 1203 Query: 945 GPRGYPGIPGPKG-ESIRGQPGPPGPQGPPGI-------GYEGRQGPPGPPGPPGPPSFP 996 G G G GP G + G+ GPPGPQGP G+ G EGR G PGPPG PG P Sbjct: 1204 GADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEP 1263 Query: 997 GPHRQTISVPGPPGPPGPPGPPGTMGAS 1024 G +PGP G GPPG G G S Sbjct: 1264 G-------LPGPEGARGPPGFKGHTGDS 1284 Score = 510 bits (1313), Expect = e-144 Identities = 334/818 (40%), Positives = 384/818 (46%), Gaps = 151/818 (18%) Query: 301 EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSP 360 E+ G LPG+ S+ T R PG E G KG+KG+PG+PG PG G PG Sbjct: 838 EKGEAGPAGPPGLPGTTSLFT--PHPRMPG----EQGPKGEKGDPGLPGEPGLQGRPGEL 891 Query: 361 CLPGPPGLP----------CPVSPLGPAGPALQTVPGPQGPPGP---PGRDGTPGRDGEP 407 GP G P P + P P PGP GPPG PG GTPG+DGE Sbjct: 892 GPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGER 951 Query: 408 GDPG---EDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHD 464 G+ G E+G PG GP+G PG PG GP PG G+ G PG +G PG PGP Sbjct: 952 GEKGAAGEEGSPGPVGPRGDPGAPGLPGP------PGKGKDGEPGLRGSPGLPGPLGTKA 1005 Query: 465 KLTFI-DMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPG 523 + E GG + ++G RG PG PG PG G PG + + PGP+G PG Sbjct: 1006 ACGKVRGSENCALGG--QCVKGDRGAPGIPGSPGSRGDPG------IGVAGPPGPSGPPG 1057 Query: 524 VPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGA-------------------- 563 G G G PG PGP GP GR+G PG G++G G+ G Sbjct: 1058 DKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDC 1117 Query: 564 ----------PGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDD 613 PG KG KG PG G G G G GP G PGPPG GP G G D Sbjct: 1118 PPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADG 1177 Query: 614 MEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGI 673 G G QG PG+PG G PG PG PGA G GA G PG G PG+EG Sbjct: 1178 EVGQ-----------KGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGP 1226 Query: 674 AGPQGPKGDRGSRGEKGDPGKDG----------VGQPGLPGPPGPPGPVVYVSEQDGSVL 723 GPQGP G G GE+G G+DG G+PGLPGP G GP + S Sbjct: 1227 PGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDS-- 1284 Query: 724 SVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPD-----GGALGP 778 PGP G G G PG G G G G G GP+G +G PG SP G + P Sbjct: 1285 GAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTP 1344 Query: 779 AQKGAKGE------PGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLG 832 QKG+KGE PGF GP GP G PG KG G G PG+PG G KGE+G+PG Sbjct: 1345 GQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPG----- 1399 Query: 833 FGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPG 892 ++G GPPG G PG PG P + + + GP GLPG GP GP G G+ G PG Sbjct: 1400 --IKGDKGPPGGKGQPGDPGIPGHKGH----TGLMGPQGLPGENGPVGPPGPPGQPGFPG 1453 Query: 893 PPGQFP-FDFL----------QLE------------AEMKGEKGDRGDAGQKGERGEPGG 929 G+ P + L QLE A MK +G G G G+ G PG Sbjct: 1454 LRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGR 1513 Query: 930 GGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGP 989 G G PG PG G G G GPKGE RG G PG PG+G G GPPG PG Sbjct: 1514 AGPMGE--PGRPGQGGLEGPSGPIGPKGE--RGAKGDPGA---PGVGLRGEMGPPGIPGQ 1566 Query: 990 PGPPSF--------PGPHRQTISVPGPPGPPGPPGPPG 1019 PG P + PGP +T G PG PGPPGPPG Sbjct: 1567 PGEPGYAKDGLPGIPGPQGET-GPAGHPGLPGPPGPPG 1603 Score = 501 bits (1290), Expect = e-141 Identities = 333/822 (40%), Positives = 383/822 (46%), Gaps = 129/822 (15%) Query: 337 GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPG 396 GL+G G PGVPGPPG G PG P G PG P P P GP G GP GPPGPPG Sbjct: 711 GLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGK-----DGPNGPPGPPG 765 Query: 397 RDGTPGRDGEPGDPGEDG------------KPGDTGPQGFPGTPGDVGPKGDKGDPGV-- 442 G PG GE G PG+ G +PG+ G G PG PG G +G+KGD G Sbjct: 766 TKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKG 825 Query: 443 -----------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPG 491 GE+G GP GPPG PG T + G+ +GP+G G Sbjct: 826 ELGLPGLKGDRGEKGEAGPAGPPGLPGT-------TSLFTPHPRMPGE----QGPKGEKG 874 Query: 492 PPGPPGVPGLPGEPGRFGVNSSDVP-------GPAGLPGVPGREGPPGFPGLPGPPGPPG 544 PG PG PGL G PG G P G G PG G G PG G PGP GPPG Sbjct: 875 DPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPG 934 Query: 545 REGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGP-----PGPPGP 599 G PG G G GE G G G +G+PGP G RG+ G G PGP G PG G Sbjct: 935 SVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGS 994 Query: 600 PGPPGP-GLPAGFDDMEGS-----GGPFWSTARSADGPQGPPGLPGLKGDPG--VPGLPG 651 PG PGP G A + GS GG + G G PG PG +GDPG V G PG Sbjct: 995 PGLPGPLGTKAACGKVRGSENCALGG---QCVKGDRGAPGIPGSPGSRGDPGIGVAGPPG 1051 Query: 652 AKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPG------- 704 G G G PG GLPG G GP G G G+ GE+G PGK G+ PG Sbjct: 1052 PSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAK 1111 Query: 705 ------PPGPPG-PVVYVSEQDGSVLSVPGPEGR---------PGFAGFPGPAGPKGNLG 748 PPGPPG P + + D V PG EG PG G PG AGP+G+ G Sbjct: 1112 DVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQG 1171 Query: 749 SKGERGSPGPKGEKGEPG--SIFSPDGGALGPAQKG---AKGEPGFRGPPGPYGRPGYKG 803 +G G G KG++G PG P G P G A G PG +G PG G PG +G Sbjct: 1172 ERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQG 1231 Query: 804 EIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAE 863 G PG PG G G G+ G PG+ G G PG PGP G GPPG + + A Sbjct: 1232 PSGLPGIPGEEGKEGRDGKPGPPGEP----GKAGEPGLPGPEGARGPPGFKGHTGDSGAP 1287 Query: 864 SSR--------PGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDR 915 R PG GLPG G GP G +G GP GPPG+ GE G Sbjct: 1288 GPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGK------NGSPGSPGEPGPS 1341 Query: 916 GDAGQKGERGEPGGGGFFGSSLP-GPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG 974 G GQKG +GE G G G P GPPG PG +G PG G G+ G+PG G +G PG Sbjct: 1342 GTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKP--GEPGFKGERGDPG 1399 Query: 975 IGYEGRQGPPGPPGPPGPPSFPGPHRQT-----ISVPG------PPGPPGPPGPPGTMGA 1023 I +G +GPPG G PG P PG T +PG PPGPPG PG PG G Sbjct: 1400 I--KGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGE 1457 Query: 1024 SSGVR-LWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNG 1064 S + L Q LG+ E +L+ A+ Y++ G Sbjct: 1458 SPSMETLRRLIQEELGKQLETRLAYLL--AQMPPAYMKSSQG 1497 Score = 470 bits (1209), Expect = e-132 Identities = 335/848 (39%), Positives = 382/848 (45%), Gaps = 161/848 (18%) Query: 239 EEGDDSDGASGDSG-SGL-GDARELLREETGAALKPRLPAPPPVTTP-PLAGGSSTEDSR 295 E+GD G G+ G GL GD E + E G A P LP + TP P G E Sbjct: 817 EKGDQ--GEKGELGLPGLKGDRGE--KGEAGPAGPPGLPGTTSLFTPHPRMPG---EQGP 869 Query: 296 SEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPG---P 350 E + G Q PG G PG + +EG G G G PG PG Sbjct: 870 KGEKGDPGLPGEPGLQGRPGELGPQ---GPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGA 926 Query: 351 PGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQT-VPGPQGPPGPPGRDGTPG-----RD 404 PG +GPPGS PG G P G G A + PGP GP G PG G PG +D Sbjct: 927 PGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKD 986 Query: 405 GEPGDPGEDGKPGDTGPQ--------------------GFPGTPGDVGPKGDKGDPGVGE 444 GEPG G G PG G + G G PG G G +GDPG+G Sbjct: 987 GEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGV 1046 Query: 445 RGPPGPQGPPGPPGPSFRHDKLTFIDMEG----SGFGGDLEALRGPRGFPG--------- 491 GPPGP GPPG G F +G G G+ RGP G PG Sbjct: 1047 AGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGN-PGERGPPGKPGLSSLLSPGD 1105 Query: 492 ------------PPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPG- 538 PPGPPG+PGLPG G GV PG G G G GPPG PG PG Sbjct: 1106 INLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGK--PGREGTEGKKGEAGPPGLPGPPGI 1163 Query: 539 --PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGP 596 P G G G G GQKG G G PG G G PGP GA G +G AG PG G PG Sbjct: 1164 AGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGK 1223 Query: 597 PGPPGPPGP-GLPA-----GFDDMEGSGGPFWSTARSAD----GPQGPPGLPGLKGDPGV 646 GPPGP GP GLP G + +G GP ++ + GP+G G PG KG G Sbjct: 1224 EGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGD 1283 Query: 647 PGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGV-GQPGLPGP 705 G PG +GE GA G+PG GLPG++G GP GP+G +G RG PGK+G G PG PGP Sbjct: 1284 SGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGP---PGKNGSPGSPGEPGP 1340 Query: 706 PGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKG---------ERGSP 756 G PG Q GS G G PG GF GP GP G G KG + G P Sbjct: 1341 SGTPG-------QKGS----KGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEP 1389 Query: 757 GPKGEKGEPG--SIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRP 814 G KGE+G+PG P GG P G G G G GP G PG G +G PG PG+P Sbjct: 1390 GFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQP 1449 Query: 815 GMNGLKGEK--------------GEPGDASLGFGMRGMP--------GPPGPPGPPGPPG 852 G GL+GE G+ + L + + MP G PGPPGPPG G Sbjct: 1450 GFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDG 1509 Query: 853 TPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEK 912 P + E RPG GL G GP GPKG +G G PG PG Sbjct: 1510 LPGR-AGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGV---------------- 1552 Query: 913 GDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPG---PRGYPGIPGPKGESIRGQPGPPGP 969 G RG+ G G G+PG G+ LPG PGP G P G+PG+PGP PGPPG Sbjct: 1553 GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGP--------PGPPGQ 1604 Query: 970 QGPPGIGY 977 P Y Sbjct: 1605 CDPSQCAY 1612 Score = 249 bits (635), Expect = 2e-65 Identities = 181/534 (33%), Positives = 219/534 (41%), Gaps = 139/534 (26%) Query: 246 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTT- 304 G GD G RE + G A P LP PP + P + G D + +Q Sbjct: 1129 GFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHP 1188 Query: 305 -----VASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAG-- 355 + G PG+D ++ G G KEG G +G G PG+PG G+ G Sbjct: 1189 GVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRD 1248 Query: 356 ----PPGSPCLPGPPGLPCPVSPLGPAG----------------------PALQTVPG-- 387 PPG P G PGLP P GP G P + +PG Sbjct: 1249 GKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKD 1308 Query: 388 ----------PQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDK 437 PQGP GPPG++G+PG GEPG G G+ G G G PG PG +GP+G Sbjct: 1309 GDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPP 1368 Query: 438 GDPGVGERGPPGPQGPPGPPG-PSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPP 496 G+PG E+G PG +G PG PG P F+ ++ GD ++G +G PG G P Sbjct: 1369 GEPG--EKGVPGKEGVPGKPGEPGFKGER------------GD-PGIKGDKGPPGGKGQP 1413 Query: 497 GVPGLPGEPGRFGV-NSSDVPGPAGLPGVPGREGPPGFPGL------------------- 536 G PG+PG G G+ +PG G G PG G PGFPGL Sbjct: 1414 GDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELG 1473 Query: 537 -------------------------PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKG 571 PGPPGPPG++G PGR G G G G G +G G Sbjct: 1474 KQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSG 1533 Query: 572 APGPAGARGESGLAGAPGPA-----GPPGPPGPPGPPG---PGLPAGFDDMEGSGGPFWS 623 GP G RG G GAPG GPPG PG PG PG GLP Sbjct: 1534 PIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLP--------------- 1578 Query: 624 TARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREG-IAGP 676 G GP G G G PG+PG PG G+ F L R G + GP Sbjct: 1579 ------GIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKGP 1626 Score = 131 bits (330), Expect = 4e-30 Identities = 100/259 (38%), Positives = 119/259 (45%), Gaps = 50/259 (19%) Query: 777 GPAQKGAKGEPGFRGPPGPYGRPGYKG--EIGFPGRPGRPGMNGLKGEKGEPGDASLGFG 834 GP Q EP PP P RP G +IGF + GEKGE G A G Sbjct: 441 GPCQVTVVTEPP---PPPPPQRPPTPGSEQIGFLKTIN---CSCPAGEKGEMGVA----G 490 Query: 835 MRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQG----PPGPKGAKGEVGP 890 G+PGP G G GP G P GP G G+ G G KG KG +G Sbjct: 491 PMGLPGPKGDIGAIGPVGAP-------------GPKGEKGDVGIGPFGQGEKGEKGSLGL 537 Query: 891 PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYP 950 PGPPG+ G KG RG+ G+ GE G PG G G GPPG PGP G Sbjct: 538 PGPPGR------------DGSKGMRGEPGELGEPGLPGEVGMRGPQ--GPPGLPGPPGRV 583 Query: 951 GIPGPKGESIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPP 1009 G PG +GE RG+ G G +G G+ G+ G+ G G G PGP GP + G Sbjct: 584 GAPGLQGE--RGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEK----GDV 637 Query: 1010 GPPGPPGPPGTMGASSGVR 1028 GP GPPG PG++ G++ Sbjct: 638 GPAGPPGVPGSVVQQEGLK 656 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 533 bits (1374), Expect = e-151 Identities = 395/1022 (38%), Positives = 445/1022 (43%), Gaps = 176/1022 (17%) Query: 241 GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 300 G S GA G+SG + G + PP T P G D Sbjct: 557 GPGSSGAKGESG------------DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPG 604 Query: 301 EQTTVASLGAQTLPG--SDSVSTWDGSVRTPGGRVKEGGLKGQKGE------PGVPGPPG 352 E G LPG D + + P G + G++G+ GE PG GP G Sbjct: 605 EPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG 664 Query: 353 RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE 412 GP G+P PG PG+ P GP G GPQG PGPPG+ G PG G PG G Sbjct: 665 LLGPRGTPGAPGQPGMAGVDGPPGPKGNM-----GPQGEPGPPGQQGNPGPQGLPGPQGP 719 Query: 413 DGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDK 465 G PG+ GPQG PG G G G G PG G GPPGPQGP G PGP Sbjct: 720 IGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 779 Query: 466 LTFIDMEGS----------GFGGDLEALR--------GPRGFPGPPGPPGVPGLPGEPGR 507 ++GS GF GD+ GPRG GP GP G G G+PG Sbjct: 780 DGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 839 Query: 508 FG-VNSSDVPGPAGLPGVPGREGP------PGFPG---------LPGPPGPPGREGPPGR 551 G G GLPG PGR+GP PGFPG + G PGP G+ GP G Sbjct: 840 SGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGP 899 Query: 552 TGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGL 607 G +G+ G G PG KG+ G GP G GE G G GP G PGP GPPGPPG PG Sbjct: 900 RGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGH 959 Query: 608 PA-----GFDDMEGSGGPFWSTARSADGPQGPPGLPGL---KGDPGVPGLPGAKGEVGAD 659 P GF G GP GPQGP G G +G PG PG PG +G GA Sbjct: 960 PGQRGETGFQGKTGPPGP-----GGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 1014 Query: 660 GVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQ 718 G G G PG +GI+G GP G RG GE+G PG G G G GP GPPGPV E+ Sbjct: 1015 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1074 Query: 719 DGSVLSVP-GPEGRPGFAGFPGPAGPKGNLGSKGERGS------------PGPKGEKGEP 765 + + P G GRPG G PGPAG KG G KG +G PGP G G P Sbjct: 1075 GSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSP 1134 Query: 766 GSIFSPDGGALG-PAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG 824 G D G +G P QKG+KG+ G GPPGP G G G G G G PG G +G G Sbjct: 1135 GE--DGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFG 1192 Query: 825 EPGDASLGFGMRGMPGPPGP---PGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGP 881 + GD G RG PGPPGP G PGPPG + +V GPPG PG +GP GP Sbjct: 1193 QKGDE----GARGFPGPPGPIGLQGLPGPPGEKGENGDV----GPMGPPGPPGPRGPQGP 1244 Query: 882 KGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFG------- 934 GA G GPPG G GEKG+ G+AG G GE G GG G Sbjct: 1245 NGADGPQGPPGSVGS---------VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGE 1295 Query: 935 SSLPGPPGPPGPRGYPGIPGPKGE----SIRGQPGPPGPQGPPGI----GYEGRQGPPGP 986 + PG GPPG +G PG GPKG G PGPPG GP G G +G G PG Sbjct: 1296 AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1355 Query: 987 PGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEV--- 1043 PGPPGP GPPGPPG GPPG GA RQ G E Sbjct: 1356 PGPPGPSG----------EAGPPGPPGKRGPPGAAGAEG-------RQGEKGAKGEAGAE 1398 Query: 1044 -PEGWLIFVAEQEELYVRVQNGFRKVQ---LEARTPLPRGTDNEVAALQPPVVQLHDSNP 1099 P G V Q G R + E P G D + PP + +P Sbjct: 1399 GPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP 1458 Query: 1100 YPRREHPHPTARPWRADDILASPP---------RLPEPQPYPGAPHHSSYVHLRPARPTS 1150 + E HP L PP LP Q PGA PA P Sbjct: 1459 GSKGEKGHPGLIG------LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIP--GPAGPLG 1510 Query: 1151 PP 1152 PP Sbjct: 1511 PP 1512 Score = 528 bits (1359), Expect = e-149 Identities = 340/784 (43%), Positives = 380/784 (48%), Gaps = 113/784 (14%) Query: 305 VASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPG 364 V +G + G + G PG + G KG+ G PG+PG PGR GP GS PG Sbjct: 813 VGQIGPRGEDGPEGPKGRAGPTGDPGPS-GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPG 871 Query: 365 PPGL------------PCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE 412 PG P P GP GP + G +GP G PG GT G DG PG PGE Sbjct: 872 FPGANGEKGARGVAGKPGPRGQRGPTGP--RGSRGARGPTGKPGPKGTSGGDGPPGPPGE 929 Query: 413 DGKPGDTGPQGFPGTPGDVGPKGDKGDPG-VGERGPPGPQGPPGPPGPSFRHDKLTFIDM 471 G G GP GFPG G GP G G PG G+RG G QG GPPGP + Sbjct: 930 RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG------GVVGP 983 Query: 472 EG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP-------GPAGLPG 523 +G +G G + G RG PGPPGPPG GLPG G+ G P GPAGL G Sbjct: 984 QGPTGETGPI----GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG 1039 Query: 524 VPGREGPPGFPGLPG------PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAG 577 PG G PG G PG P GPPG G PG G G+ G G PG G +G PGPAG Sbjct: 1040 FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG 1099 Query: 578 ARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGG----PFWSTARSADGPQG 633 +G G G GPAG G GP G PGP PAG +G G P ++ G G Sbjct: 1100 EKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1159 Query: 634 PPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPG 693 PPG PGL+G G PG+ G GE G G G G G EG G GP G G +G G PG Sbjct: 1160 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1219 Query: 694 KDG----VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKG---- 745 + G VG G PGPPGP GP +G+ GP+G PG G G G KG Sbjct: 1220 EKGENGDVGPMGPPGPPGPRGP----QGPNGA----DGPQGPPGSVGSVGGVGEKGEPGE 1271 Query: 746 --NLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKG 803 N G GE G GPKGE+GE G P GA GP GAKG PG GP G G G+ G Sbjct: 1272 AGNPGPPGEAGVGGPKGERGEKGEAGPP--GAAGPP--GAKGPPGDDGPKGNPGPVGFPG 1327 Query: 804 EIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAE 863 + G PG PG G +G+ G+KGE GD G PGPPGP G GPPG P Sbjct: 1328 DPGPPGEPGPAGQDGVGGDKGEDGDP-------GQPGPPGPSGEAGPPGPP--------- 1371 Query: 864 SSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGE 923 + GPPG G +G G KGAKGE G GPPG+ Q A G +G RG G GE Sbjct: 1372 -GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGE 1430 Query: 924 RGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGES----------------IRGQPGPP 967 +G PG G G PGP GPPG G G PG KGE +G G P Sbjct: 1431 QGLPGAAGQDGP--PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1488 Query: 968 GPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPH--RQTISVPGP---------PGPPGPP 1015 G QG PG G G GP GP GPPGPP PGP + GP PGPPG P Sbjct: 1489 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP 1548 Query: 1016 GPPG 1019 GPPG Sbjct: 1549 GPPG 1552 Score = 496 bits (1277), Expect = e-140 Identities = 339/846 (40%), Positives = 385/846 (45%), Gaps = 187/846 (22%) Query: 329 PGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPL----------GPA 378 P G G G +G G PG PG GPPG P LPG GLP P + G Sbjct: 458 PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 517 Query: 379 GP------------------ALQTVPGPQ------GPPGPPGRDGTPGRDGEP------- 407 GP AL+ PGP GP G PG G G G+P Sbjct: 518 GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 577 Query: 408 --------GDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV----GERGPPGPQGPPG 455 G PG+ G+PG G +G PG PG G +G G PG+ G RG GPQGPPG Sbjct: 578 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 637 Query: 456 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 515 PPG + I G L GPRG PG PG PG+ G+ G PG G Sbjct: 638 PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKG-----N 692 Query: 516 PGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGP 575 GP G PG PG++G PG GLPGP GP GPPG G +G G AG PG G G PG Sbjct: 693 MGPQGEPGPPGQQGNPGPQGLPGPQGP---IGPPGEKGPQGKPGLAGLPGADGPPGHPGK 749 Query: 576 AGARGESGLAGAPGPAGPPGPPGPPGPPG----------------PGLPAGFDDM--EGS 617 G GE G G PGP GP G PGP G G G P DM +G Sbjct: 750 EGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGD 809 Query: 618 GGPFWSTA-RSADGPQGPPGLPGLKGD---------------PGVPGLPGAKGEVGADGV 661 G R DGP+GP G G GD PG+PG PG +G G+ G Sbjct: 810 RGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 869 Query: 662 PGFPGL------------PGREGIAGPQGPKGDRGSRGEKGDPGKDGV-------GQPGL 702 PGFPG PG G GP GP+G RG+RG G PG G G PG Sbjct: 870 PGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGE 929 Query: 703 PGPPGPPGPVVYVSE--------QDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERG 754 GP GP GPV + +DG + PG G GF G GP GP G +G +G G Sbjct: 930 RGPQGPQGPVGFPGPKGPPGPPGKDG-LPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTG 988 Query: 755 SPGPKGEKGEPGSIFSP-DGGALGPAQK-GAKGEP---GFRGPPGPYGRPGYKGEIGFPG 809 GP GE+G PG P + G G A K GAKG+P G G GP G G+ GE G PG Sbjct: 989 ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 1048 Query: 810 RPGRPGMNGLKGEKGEPGD-------ASLG-FGMRGMPGPPGPPGPPGPPGTPVYDSNVF 861 G PG+ G +G +G PG S G G G+PG PGP GPPGP G Sbjct: 1049 AQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG--------- 1099 Query: 862 AESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQK 921 G PG G QGP G G +G VG PGP G A GE GD+G+ G+ Sbjct: 1100 ----EKGAPGEKGPQGPAGRDGVQGPVGLPGPAG---------PAGSPGEDGDKGEIGEP 1146 Query: 922 GERGEPGGGGFFGSSLPGPPGPPGPRGYPGI------PGPKG----------ESIRGQPG 965 G++G G G G PGPPG GP G PGI PGP+G E RG PG Sbjct: 1147 GQKGSKGDKGENGP--PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1204 Query: 966 PPGP---QGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTM 1021 PPGP QG PG G +G G GP GPPGPP GP GP G GP GPPG++ Sbjct: 1205 PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ-------GPNGADGPQGPPGSV 1257 Query: 1022 GASSGV 1027 G+ GV Sbjct: 1258 GSVGGV 1263 Score = 436 bits (1121), Expect = e-122 Identities = 333/880 (37%), Positives = 384/880 (43%), Gaps = 166/880 (18%) Query: 391 PPGPPGRDGTPGRDGEPG----DPGEDGKPGDTGPQGFPGT--PGDV--GPKGDKGDPGV 442 P PP + PG E G G+ G +G P PG + GP G G G+ Sbjct: 405 PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 464 Query: 443 GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLP 502 GPPG QGP GPPG G RG PG PG PG GLP Sbjct: 465 --MGPPGLQGPTGPPGDP------------------------GDRGPPGRPGLPGADGLP 498 Query: 503 GEPG-------RFGVNSSDVP---------------------GPAGLPGVPGREGPPGFP 534 G PG R+G + S P GP G G+ GR GP G P Sbjct: 499 GPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGP 558 Query: 535 GL---------PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLA 585 G PGP GP G +GPPG TG+ G G GA G +G G PG G RG GL Sbjct: 559 GSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLP 618 Query: 586 GAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGG-------PFWSTARSADGPQGPPGLP 638 G PG G G GP GPPG P G D M G G P + R GP+G PG P Sbjct: 619 GLPGDKGHRGERGPQGPPG---PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAP 675 Query: 639 GLKGDPGVPGLPGAKGEVGADGVPGFPGL---PGREGIAGPQGPKGDRGSRGEKGDPGKD 695 G G GV G PG KG +G G PG PG PG +G+ GPQGP G G +G +G PG Sbjct: 676 GQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLA 735 Query: 696 GVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGS 755 G+ PG GPPG PG E+ L PGP+G G+PGP G KG G +G +GS Sbjct: 736 GL--PGADGPPGHPGKEGQSGEK--GALGPPGPQGP---IGYPGPRGVKGADGVRGLKGS 788 Query: 756 PGPKGEKGEPGSIFSPDGGALGP----AQKGAKGEPGFRGP---------PGPYGRPGYK 802 G KGE G PG F D G G Q G +GE G GP PGP G+ G K Sbjct: 789 KGEKGEDGFPG--FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEK 846 Query: 803 GEIGFPGRPGRPGMNGLKGEKGEPG--DASLGFGMRGMPGPPGPPGPPGPPGT------- 853 G++G PG PG PG G KG G PG A+ G RG+ G PGP G GP G Sbjct: 847 GKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGAR 906 Query: 854 -PVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEK 912 P S GPPG PG +GP GP+G G GP GPPG D L G Sbjct: 907 GPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL------PGHP 960 Query: 913 GDRGDAGQKGERGEPGGGGFFG-------------SSLPGPPGPPGPRGYPGI------- 952 G RG+ G +G+ G PG GG G PGPPGPPG +G PG Sbjct: 961 GQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAK 1020 Query: 953 --PGPKGES-------IRGQPGP---PGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPH 999 PGP+G S +RG PG PG QG PG+ G EG QGPPGP G PG G Sbjct: 1021 GDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGT- 1079 Query: 1000 RQTISVPGPPGPPGPPGPPGTMGA--SSGVRLWATRQAMLGQV----HEVPEGWLIFVAE 1053 I +PG PGP GPPGP G GA G + A R + G V P G + Sbjct: 1080 AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGD 1139 Query: 1054 QEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPW 1113 + E+ Q G + + E P P G V A P + D P PR + + Sbjct: 1140 KGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGA---PGIAGGDGEPGPRGQQGMFGQKGD 1196 Query: 1114 RADDILASPPRLPEPQPYPGAP-HHSSYVHLRPARPTSPP 1152 PP Q PG P + P P PP Sbjct: 1197 EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPP 1236 Score = 362 bits (929), Expect = 1e-99 Identities = 236/553 (42%), Positives = 260/553 (47%), Gaps = 103/553 (18%) Query: 309 GAQTLPGSDSVSTWDGSVRT---PGGRVKEG-----GLKGQKGEPGVPGPPGRAGPPGSP 360 GA+ PG +S DG PG R G GLKG +G G PGP G G GS Sbjct: 1018 GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA 1077 Query: 361 CLPGPPGLPCPVSPLGPAGPALQT-VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT 419 GP GLP P GP GPA + PG +GP GP GRDG G G PG G G PG+ Sbjct: 1078 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGED 1137 Query: 420 GPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS-GFGG 478 G +G G PG G KGDKG+ G GPPG QGP G PG + + +G G G Sbjct: 1138 GDKGEIGEPGQKGSKGDKGENG--PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKG 1195 Query: 479 DLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPG 538 D G RGFPGPPGP G+ GLPG PG G N DV GP G PG PG GP G G G Sbjct: 1196 D----EGARGFPGPPGPIGLQGLPGPPGEKGENG-DV-GPMGPPGPPGPRGPQGPNGADG 1249 Query: 539 PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPG 598 P GPPG G G G+KG GEAG PG G G GP G RGE G AG PG AGPPG G Sbjct: 1250 PQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG 1309 Query: 599 PPG------------------PPGPGLPAGFDDMEGS----GGPFWSTARSADGPQGPPG 636 PPG PPG PAG D + G G P G GPPG Sbjct: 1310 PPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG 1369 Query: 637 LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGP----------------- 679 PG +G PG G G +GE GA G G G PG+ G GPQGP Sbjct: 1370 PPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG 1429 Query: 680 -------------------------KGDRGSRGEKGDPGKDGV----------GQPGLPG 704 KGD GS+GEKG PG G+ G GLPG Sbjct: 1430 EQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1489 Query: 705 PPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGS------KGERGSPGP 758 G PG ++ DG + GP G PG G PGP GPKGN GS KG+ G PGP Sbjct: 1490 TQGSPG-----AKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP 1544 Query: 759 KGEKGEPGSIFSP 771 G G PG + P Sbjct: 1545 PGSPGPPGEVIQP 1557 Score = 347 bits (891), Expect = 3e-95 Identities = 226/509 (44%), Positives = 251/509 (49%), Gaps = 84/509 (16%) Query: 279 PVTTPPLAG--GSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPG------ 330 PV P AG GS ED E+ E S G + G G V PG Sbjct: 1121 PVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1180 Query: 331 --GRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP---VSPLGPAGPALQTV 385 G + G+ GQKG+ G G PG GP G LPGPPG V P+GP GP Sbjct: 1181 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP----- 1235 Query: 386 PGPQGPPGPPGRDGT---PGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV 442 PGP+GP GP G DG PG G G GE G+PG+ G G PG G GPKG++G+ G Sbjct: 1236 PGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG- 1294 Query: 443 GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLP 502 E GPPG GPPG GP G D GP+G PGP G PG PG P Sbjct: 1295 -EAGPPGAAGPPGAKGPP----------------GDD-----GPKGNPGPVGFPGDPGPP 1332 Query: 503 GEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAG 562 GEPG PAG GV G +G G PG PGPPGP G GPPG G++G G AG Sbjct: 1333 GEPG-----------PAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAG 1381 Query: 563 APGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFW 622 A G +G KGA G AGA G G G GP GP G PGP G G P G + G+ G Sbjct: 1382 AEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAG--- 1438 Query: 623 STARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGD 682 GP GPPGLPGLKGD PG+KGE G PGL G G G QG KGD Sbjct: 1439 --QDGPPGPMGPPGLPGLKGD------PGSKGE------KGHPGLIGLIGPPGEQGEKGD 1484 Query: 683 RGSRGEKGDPGKDGVGQ-PGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPA 741 RG G +G PG G G PG GP GPPGP +PGP+G G G GPA Sbjct: 1485 RGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP-----------GLPGPQGPKGNKGSTGPA 1533 Query: 742 GPKGNLGSKGERGSPGPKGEKGEPGSIFS 770 G KG+ G G GSPGP GE +P I S Sbjct: 1534 GQKGDSGLPGPPGSPGPPGEVIQPLPILS 1562 Score = 52.4 bits (124), Expect = 3e-06 Identities = 45/172 (26%), Positives = 71/172 (41%), Gaps = 10/172 (5%) Query: 67 AYVFGPDANSGQVARYHFPS-LFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKL 125 AY A + FP F DFS+LF ++P L +I + G++ Sbjct: 73 AYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYNEH------GIQQ 126 Query: 126 SGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFV-GQWTHLALSVAGGFVALYVDCEEFQ 184 GV+ G + L G FR G+W +A+SV V + VDC++ Sbjct: 127 IGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDCKKKT 186 Query: 185 RMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHC 236 PL RS R + G +F + D + F+G I + + DP+ + +C Sbjct: 187 TKPLDRSERAIVDTNGITVFGTRI--LDEEVFEGDIQQFLITGDPKAAYDYC 236 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 533 bits (1374), Expect = e-151 Identities = 395/1022 (38%), Positives = 445/1022 (43%), Gaps = 176/1022 (17%) Query: 241 GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 300 G S GA G+SG + G + PP T P G D Sbjct: 506 GPGSSGAKGESG------------DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPG 553 Query: 301 EQTTVASLGAQTLPG--SDSVSTWDGSVRTPGGRVKEGGLKGQKGE------PGVPGPPG 352 E G LPG D + + P G + G++G+ GE PG GP G Sbjct: 554 EPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG 613 Query: 353 RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE 412 GP G+P PG PG+ P GP G GPQG PGPPG+ G PG G PG G Sbjct: 614 LLGPRGTPGAPGQPGMAGVDGPPGPKGNM-----GPQGEPGPPGQQGNPGPQGLPGPQGP 668 Query: 413 DGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDK 465 G PG+ GPQG PG G G G G PG G GPPGPQGP G PGP Sbjct: 669 IGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 728 Query: 466 LTFIDMEGS----------GFGGDLEALR--------GPRGFPGPPGPPGVPGLPGEPGR 507 ++GS GF GD+ GPRG GP GP G G G+PG Sbjct: 729 DGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 788 Query: 508 FG-VNSSDVPGPAGLPGVPGREGP------PGFPG---------LPGPPGPPGREGPPGR 551 G G GLPG PGR+GP PGFPG + G PGP G+ GP G Sbjct: 789 SGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGP 848 Query: 552 TGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGL 607 G +G+ G G PG KG+ G GP G GE G G GP G PGP GPPGPPG PG Sbjct: 849 RGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGH 908 Query: 608 PA-----GFDDMEGSGGPFWSTARSADGPQGPPGLPGL---KGDPGVPGLPGAKGEVGAD 659 P GF G GP GPQGP G G +G PG PG PG +G GA Sbjct: 909 PGQRGETGFQGKTGPPGP-----GGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 963 Query: 660 GVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQ 718 G G G PG +GI+G GP G RG GE+G PG G G G GP GPPGPV E+ Sbjct: 964 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1023 Query: 719 DGSVLSVP-GPEGRPGFAGFPGPAGPKGNLGSKGERGS------------PGPKGEKGEP 765 + + P G GRPG G PGPAG KG G KG +G PGP G G P Sbjct: 1024 GSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSP 1083 Query: 766 GSIFSPDGGALG-PAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG 824 G D G +G P QKG+KG+ G GPPGP G G G G G G PG G +G G Sbjct: 1084 GE--DGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFG 1141 Query: 825 EPGDASLGFGMRGMPGPPGP---PGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGP 881 + GD G RG PGPPGP G PGPPG + +V GPPG PG +GP GP Sbjct: 1142 QKGDE----GARGFPGPPGPIGLQGLPGPPGEKGENGDV----GPMGPPGPPGPRGPQGP 1193 Query: 882 KGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFG------- 934 GA G GPPG G GEKG+ G+AG G GE G GG G Sbjct: 1194 NGADGPQGPPGSVGS---------VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGE 1244 Query: 935 SSLPGPPGPPGPRGYPGIPGPKGE----SIRGQPGPPGPQGPPGI----GYEGRQGPPGP 986 + PG GPPG +G PG GPKG G PGPPG GP G G +G G PG Sbjct: 1245 AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1304 Query: 987 PGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEV--- 1043 PGPPGP GPPGPPG GPPG GA RQ G E Sbjct: 1305 PGPPGPSG----------EAGPPGPPGKRGPPGAAGAEG-------RQGEKGAKGEAGAE 1347 Query: 1044 -PEGWLIFVAEQEELYVRVQNGFRKVQ---LEARTPLPRGTDNEVAALQPPVVQLHDSNP 1099 P G V Q G R + E P G D + PP + +P Sbjct: 1348 GPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP 1407 Query: 1100 YPRREHPHPTARPWRADDILASPP---------RLPEPQPYPGAPHHSSYVHLRPARPTS 1150 + E HP L PP LP Q PGA PA P Sbjct: 1408 GSKGEKGHPGLIG------LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIP--GPAGPLG 1459 Query: 1151 PP 1152 PP Sbjct: 1460 PP 1461 Score = 528 bits (1359), Expect = e-149 Identities = 340/784 (43%), Positives = 380/784 (48%), Gaps = 113/784 (14%) Query: 305 VASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPG 364 V +G + G + G PG + G KG+ G PG+PG PGR GP GS PG Sbjct: 762 VGQIGPRGEDGPEGPKGRAGPTGDPGPS-GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPG 820 Query: 365 PPGL------------PCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE 412 PG P P GP GP + G +GP G PG GT G DG PG PGE Sbjct: 821 FPGANGEKGARGVAGKPGPRGQRGPTGP--RGSRGARGPTGKPGPKGTSGGDGPPGPPGE 878 Query: 413 DGKPGDTGPQGFPGTPGDVGPKGDKGDPG-VGERGPPGPQGPPGPPGPSFRHDKLTFIDM 471 G G GP GFPG G GP G G PG G+RG G QG GPPGP + Sbjct: 879 RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG------GVVGP 932 Query: 472 EG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP-------GPAGLPG 523 +G +G G + G RG PGPPGPPG GLPG G+ G P GPAGL G Sbjct: 933 QGPTGETGPI----GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG 988 Query: 524 VPGREGPPGFPGLPG------PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAG 577 PG G PG G PG P GPPG G PG G G+ G G PG G +G PGPAG Sbjct: 989 FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG 1048 Query: 578 ARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGG----PFWSTARSADGPQG 633 +G G G GPAG G GP G PGP PAG +G G P ++ G G Sbjct: 1049 EKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1108 Query: 634 PPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPG 693 PPG PGL+G G PG+ G GE G G G G G EG G GP G G +G G PG Sbjct: 1109 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1168 Query: 694 KDG----VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKG---- 745 + G VG G PGPPGP GP +G+ GP+G PG G G G KG Sbjct: 1169 EKGENGDVGPMGPPGPPGPRGP----QGPNGA----DGPQGPPGSVGSVGGVGEKGEPGE 1220 Query: 746 --NLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKG 803 N G GE G GPKGE+GE G P GA GP GAKG PG GP G G G+ G Sbjct: 1221 AGNPGPPGEAGVGGPKGERGEKGEAGPP--GAAGPP--GAKGPPGDDGPKGNPGPVGFPG 1276 Query: 804 EIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAE 863 + G PG PG G +G+ G+KGE GD G PGPPGP G GPPG P Sbjct: 1277 DPGPPGEPGPAGQDGVGGDKGEDGDP-------GQPGPPGPSGEAGPPGPP--------- 1320 Query: 864 SSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGE 923 + GPPG G +G G KGAKGE G GPPG+ Q A G +G RG G GE Sbjct: 1321 -GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGE 1379 Query: 924 RGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGES----------------IRGQPGPP 967 +G PG G G PGP GPPG G G PG KGE +G G P Sbjct: 1380 QGLPGAAGQDGP--PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1437 Query: 968 GPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPH--RQTISVPGP---------PGPPGPP 1015 G QG PG G G GP GP GPPGPP PGP + GP PGPPG P Sbjct: 1438 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP 1497 Query: 1016 GPPG 1019 GPPG Sbjct: 1498 GPPG 1501 Score = 496 bits (1277), Expect = e-140 Identities = 339/846 (40%), Positives = 385/846 (45%), Gaps = 187/846 (22%) Query: 329 PGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPL----------GPA 378 P G G G +G G PG PG GPPG P LPG GLP P + G Sbjct: 407 PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 466 Query: 379 GP------------------ALQTVPGPQ------GPPGPPGRDGTPGRDGEP------- 407 GP AL+ PGP GP G PG G G G+P Sbjct: 467 GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 526 Query: 408 --------GDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV----GERGPPGPQGPPG 455 G PG+ G+PG G +G PG PG G +G G PG+ G RG GPQGPPG Sbjct: 527 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 586 Query: 456 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 515 PPG + I G L GPRG PG PG PG+ G+ G PG G Sbjct: 587 PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKG-----N 641 Query: 516 PGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGP 575 GP G PG PG++G PG GLPGP GP GPPG G +G G AG PG G G PG Sbjct: 642 MGPQGEPGPPGQQGNPGPQGLPGPQGP---IGPPGEKGPQGKPGLAGLPGADGPPGHPGK 698 Query: 576 AGARGESGLAGAPGPAGPPGPPGPPGPPG----------------PGLPAGFDDM--EGS 617 G GE G G PGP GP G PGP G G G P DM +G Sbjct: 699 EGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGD 758 Query: 618 GGPFWSTA-RSADGPQGPPGLPGLKGD---------------PGVPGLPGAKGEVGADGV 661 G R DGP+GP G G GD PG+PG PG +G G+ G Sbjct: 759 RGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 818 Query: 662 PGFPGL------------PGREGIAGPQGPKGDRGSRGEKGDPGKDGV-------GQPGL 702 PGFPG PG G GP GP+G RG+RG G PG G G PG Sbjct: 819 PGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGE 878 Query: 703 PGPPGPPGPVVYVSE--------QDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERG 754 GP GP GPV + +DG + PG G GF G GP GP G +G +G G Sbjct: 879 RGPQGPQGPVGFPGPKGPPGPPGKDG-LPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTG 937 Query: 755 SPGPKGEKGEPGSIFSP-DGGALGPAQK-GAKGEP---GFRGPPGPYGRPGYKGEIGFPG 809 GP GE+G PG P + G G A K GAKG+P G G GP G G+ GE G PG Sbjct: 938 ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 997 Query: 810 RPGRPGMNGLKGEKGEPGD-------ASLG-FGMRGMPGPPGPPGPPGPPGTPVYDSNVF 861 G PG+ G +G +G PG S G G G+PG PGP GPPGP G Sbjct: 998 AQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG--------- 1048 Query: 862 AESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQK 921 G PG G QGP G G +G VG PGP G A GE GD+G+ G+ Sbjct: 1049 ----EKGAPGEKGPQGPAGRDGVQGPVGLPGPAG---------PAGSPGEDGDKGEIGEP 1095 Query: 922 GERGEPGGGGFFGSSLPGPPGPPGPRGYPGI------PGPKG----------ESIRGQPG 965 G++G G G G PGPPG GP G PGI PGP+G E RG PG Sbjct: 1096 GQKGSKGDKGENGP--PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1153 Query: 966 PPGP---QGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTM 1021 PPGP QG PG G +G G GP GPPGPP GP GP G GP GPPG++ Sbjct: 1154 PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ-------GPNGADGPQGPPGSV 1206 Query: 1022 GASSGV 1027 G+ GV Sbjct: 1207 GSVGGV 1212 Score = 461 bits (1185), Expect = e-129 Identities = 401/1208 (33%), Positives = 498/1208 (41%), Gaps = 217/1208 (17%) Query: 67 AYVFGPDANSGQVARYHFPS-LFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKL 125 AY A + FP F DFS+LF ++P L +I + G++ Sbjct: 73 AYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYNEH------GIQQ 126 Query: 126 SGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFV-GQWTHLALSVAGGFVALYVDCEEFQ 184 GV+ G + L G FR G+W +A+SV V + VDC++ Sbjct: 127 IGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDCKKKT 186 Query: 185 RMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDS 244 PL RS R + G +F + D + F+G I + + DP+ + +C + D Sbjct: 187 TKPLDRSERAIVDTNGITVFGTRI--LDEEVFEGDIQQFLITGDPKAAYDYC-EHYSPDC 243 Query: 245 DGASG----------DSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDS 294 D ++ D + + D +E G + AP V+ + E + Sbjct: 244 DSSAPKAAQAQEPQIDEANIVDDFQEY---NYGTMESYQTEAPRHVS-------GTNEPN 293 Query: 295 RSEEV--EEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPG 352 EE+ EE T +Q D++ + GR + + G GE Sbjct: 294 PVEEIFTEEYLTGEDYDSQRKNSEDTLY----ENKEIDGRDSDLLVDGDLGEYDFYEYKE 349 Query: 353 RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE 412 P SP P GP PA + + + G G+ G+ Sbjct: 350 YEDKPTSP----------PNEEFGPGVPAETDIT-----------ETSINGHGAYGEKGQ 388 Query: 413 DGKPGDTGPQGF-PGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDM 471 G+P P G PG GP G G PG+ GP GPPG PG Sbjct: 389 KGEPAVVEPGMLVEGPPGPAGPAGIMGPPGL-----QGPTGPPGDPGD------------ 431 Query: 472 EGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGE----PGRFGVNSSDVP----------- 516 RGP G PG PG G+PG PG P R+G + S P Sbjct: 432 ------------RGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQA 479 Query: 517 ----------GPAGLPGVPGREGPPGFPGL---------PGPPGPPGREGPPGRTGQKGS 557 GP G G+ GR GP G PG PGP GP G +GPPG TG+ G Sbjct: 480 ILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGK 539 Query: 558 LGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGS 617 G GA G +G G PG G RG GL G PG G G GP GPPG P G D M G Sbjct: 540 RGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG---PPGDDGMRGE 596 Query: 618 GG-------PFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGL--- 667 G P + R GP+G PG PG G GV G PG KG +G G PG PG Sbjct: 597 DGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGN 656 Query: 668 PGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPG 727 PG +G+ GPQGP G G +G +G PG G+ PG GPPG PG E+ L PG Sbjct: 657 PGPQGLPGPQGPIGPPGEKGPQGKPGLAGL--PGADGPPGHPGKEGQSGEK--GALGPPG 712 Query: 728 PEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGP----AQKGA 783 P+G G+PGP G KG G +G +GS G KGE G PG F D G G Q G Sbjct: 713 PQGP---IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG--FKGDMGLKGDRGEVGQIGP 767 Query: 784 KGEPGFRGP---------PGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPG--DASLG 832 +GE G GP PGP G+ G KG++G PG PG PG G KG G PG A+ Sbjct: 768 RGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGE 827 Query: 833 FGMRGMPGPPGPPGPPGPPGT--------PVYDSNVFAESSRPGPPGLPGNQGPPGPKGA 884 G RG+ G PGP G GP G P S GPPG PG +GP GP+G Sbjct: 828 KGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP 887 Query: 885 KGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFG---------- 934 G GP GPPG D L G G RG+ G +G+ G PG GG G Sbjct: 888 VGFPGPKGPPGPPGKDGL------PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGP 941 Query: 935 ---SSLPGPPGPPGPRGYPGI---------PGPKGES-------IRGQPGP---PGPQGP 972 PGPPGPPG +G PG PGP+G S +RG PG PG QG Sbjct: 942 IGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA 1001 Query: 973 PGI-GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGA--SSGVRL 1029 PG+ G EG QGPPGP G PG G I +PG PGP GPPGP G GA G + Sbjct: 1002 PGLKGGEGPQGPPGPVGSPGERGSAGT-AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQG 1060 Query: 1030 WATRQAMLGQV----HEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVA 1085 A R + G V P G ++ E+ Q G + + E P P G V Sbjct: 1061 PAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG 1120 Query: 1086 ALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAP-HHSSYVHLR 1144 A P + D P PR + + PP Q PG P + Sbjct: 1121 A---PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVG 1177 Query: 1145 PARPTSPP 1152 P P PP Sbjct: 1178 PMGPPGPP 1185 Score = 362 bits (929), Expect = 1e-99 Identities = 236/553 (42%), Positives = 260/553 (47%), Gaps = 103/553 (18%) Query: 309 GAQTLPGSDSVSTWDGSVRT---PGGRVKEG-----GLKGQKGEPGVPGPPGRAGPPGSP 360 GA+ PG +S DG PG R G GLKG +G G PGP G G GS Sbjct: 967 GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA 1026 Query: 361 CLPGPPGLPCPVSPLGPAGPALQT-VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT 419 GP GLP P GP GPA + PG +GP GP GRDG G G PG G G PG+ Sbjct: 1027 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGED 1086 Query: 420 GPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS-GFGG 478 G +G G PG G KGDKG+ G GPPG QGP G PG + + +G G G Sbjct: 1087 GDKGEIGEPGQKGSKGDKGENG--PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKG 1144 Query: 479 DLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPG 538 D G RGFPGPPGP G+ GLPG PG G N DV GP G PG PG GP G G G Sbjct: 1145 D----EGARGFPGPPGPIGLQGLPGPPGEKGENG-DV-GPMGPPGPPGPRGPQGPNGADG 1198 Query: 539 PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPG 598 P GPPG G G G+KG GEAG PG G G GP G RGE G AG PG AGPPG G Sbjct: 1199 PQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG 1258 Query: 599 PPG------------------PPGPGLPAGFDDMEGS----GGPFWSTARSADGPQGPPG 636 PPG PPG PAG D + G G P G GPPG Sbjct: 1259 PPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG 1318 Query: 637 LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGP----------------- 679 PG +G PG G G +GE GA G G G PG+ G GPQGP Sbjct: 1319 PPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG 1378 Query: 680 -------------------------KGDRGSRGEKGDPGKDGV----------GQPGLPG 704 KGD GS+GEKG PG G+ G GLPG Sbjct: 1379 EQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1438 Query: 705 PPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGS------KGERGSPGP 758 G PG ++ DG + GP G PG G PGP GPKGN GS KG+ G PGP Sbjct: 1439 TQGSPG-----AKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP 1493 Query: 759 KGEKGEPGSIFSP 771 G G PG + P Sbjct: 1494 PGSPGPPGEVIQP 1506 Score = 347 bits (891), Expect = 3e-95 Identities = 226/509 (44%), Positives = 251/509 (49%), Gaps = 84/509 (16%) Query: 279 PVTTPPLAG--GSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPG------ 330 PV P AG GS ED E+ E S G + G G V PG Sbjct: 1070 PVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1129 Query: 331 --GRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP---VSPLGPAGPALQTV 385 G + G+ GQKG+ G G PG GP G LPGPPG V P+GP GP Sbjct: 1130 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP----- 1184 Query: 386 PGPQGPPGPPGRDGT---PGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV 442 PGP+GP GP G DG PG G G GE G+PG+ G G PG G GPKG++G+ G Sbjct: 1185 PGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG- 1243 Query: 443 GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLP 502 E GPPG GPPG GP G D GP+G PGP G PG PG P Sbjct: 1244 -EAGPPGAAGPPGAKGPP----------------GDD-----GPKGNPGPVGFPGDPGPP 1281 Query: 503 GEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAG 562 GEPG PAG GV G +G G PG PGPPGP G GPPG G++G G AG Sbjct: 1282 GEPG-----------PAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAG 1330 Query: 563 APGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFW 622 A G +G KGA G AGA G G G GP GP G PGP G G P G + G+ G Sbjct: 1331 AEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAG--- 1387 Query: 623 STARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGD 682 GP GPPGLPGLKGD PG+KGE G PGL G G G QG KGD Sbjct: 1388 --QDGPPGPMGPPGLPGLKGD------PGSKGE------KGHPGLIGLIGPPGEQGEKGD 1433 Query: 683 RGSRGEKGDPGKDGVGQ-PGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPA 741 RG G +G PG G G PG GP GPPGP +PGP+G G G GPA Sbjct: 1434 RGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP-----------GLPGPQGPKGNKGSTGPA 1482 Query: 742 GPKGNLGSKGERGSPGPKGEKGEPGSIFS 770 G KG+ G G GSPGP GE +P I S Sbjct: 1483 GQKGDSGLPGPPGSPGPPGEVIQPLPILS 1511 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 533 bits (1374), Expect = e-151 Identities = 395/1022 (38%), Positives = 445/1022 (43%), Gaps = 176/1022 (17%) Query: 241 GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 300 G S GA G+SG + G + PP T P G D Sbjct: 545 GPGSSGAKGESG------------DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPG 592 Query: 301 EQTTVASLGAQTLPG--SDSVSTWDGSVRTPGGRVKEGGLKGQKGE------PGVPGPPG 352 E G LPG D + + P G + G++G+ GE PG GP G Sbjct: 593 EPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG 652 Query: 353 RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE 412 GP G+P PG PG+ P GP G GPQG PGPPG+ G PG G PG G Sbjct: 653 LLGPRGTPGAPGQPGMAGVDGPPGPKGNM-----GPQGEPGPPGQQGNPGPQGLPGPQGP 707 Query: 413 DGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDK 465 G PG+ GPQG PG G G G G PG G GPPGPQGP G PGP Sbjct: 708 IGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 767 Query: 466 LTFIDMEGS----------GFGGDLEALR--------GPRGFPGPPGPPGVPGLPGEPGR 507 ++GS GF GD+ GPRG GP GP G G G+PG Sbjct: 768 DGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 827 Query: 508 FG-VNSSDVPGPAGLPGVPGREGP------PGFPG---------LPGPPGPPGREGPPGR 551 G G GLPG PGR+GP PGFPG + G PGP G+ GP G Sbjct: 828 SGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGP 887 Query: 552 TGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGL 607 G +G+ G G PG KG+ G GP G GE G G GP G PGP GPPGPPG PG Sbjct: 888 RGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGH 947 Query: 608 PA-----GFDDMEGSGGPFWSTARSADGPQGPPGLPGL---KGDPGVPGLPGAKGEVGAD 659 P GF G GP GPQGP G G +G PG PG PG +G GA Sbjct: 948 PGQRGETGFQGKTGPPGP-----GGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 1002 Query: 660 GVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQ 718 G G G PG +GI+G GP G RG GE+G PG G G G GP GPPGPV E+ Sbjct: 1003 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1062 Query: 719 DGSVLSVP-GPEGRPGFAGFPGPAGPKGNLGSKGERGS------------PGPKGEKGEP 765 + + P G GRPG G PGPAG KG G KG +G PGP G G P Sbjct: 1063 GSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSP 1122 Query: 766 GSIFSPDGGALG-PAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG 824 G D G +G P QKG+KG+ G GPPGP G G G G G G PG G +G G Sbjct: 1123 GE--DGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFG 1180 Query: 825 EPGDASLGFGMRGMPGPPGP---PGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGP 881 + GD G RG PGPPGP G PGPPG + +V GPPG PG +GP GP Sbjct: 1181 QKGDE----GARGFPGPPGPIGLQGLPGPPGEKGENGDV----GPMGPPGPPGPRGPQGP 1232 Query: 882 KGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFG------- 934 GA G GPPG G GEKG+ G+AG G GE G GG G Sbjct: 1233 NGADGPQGPPGSVGS---------VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGE 1283 Query: 935 SSLPGPPGPPGPRGYPGIPGPKGE----SIRGQPGPPGPQGPPGI----GYEGRQGPPGP 986 + PG GPPG +G PG GPKG G PGPPG GP G G +G G PG Sbjct: 1284 AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1343 Query: 987 PGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEV--- 1043 PGPPGP GPPGPPG GPPG GA RQ G E Sbjct: 1344 PGPPGPSG----------EAGPPGPPGKRGPPGAAGAEG-------RQGEKGAKGEAGAE 1386 Query: 1044 -PEGWLIFVAEQEELYVRVQNGFRKVQ---LEARTPLPRGTDNEVAALQPPVVQLHDSNP 1099 P G V Q G R + E P G D + PP + +P Sbjct: 1387 GPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP 1446 Query: 1100 YPRREHPHPTARPWRADDILASPP---------RLPEPQPYPGAPHHSSYVHLRPARPTS 1150 + E HP L PP LP Q PGA PA P Sbjct: 1447 GSKGEKGHPGLIG------LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIP--GPAGPLG 1498 Query: 1151 PP 1152 PP Sbjct: 1499 PP 1500 Score = 528 bits (1359), Expect = e-149 Identities = 340/784 (43%), Positives = 380/784 (48%), Gaps = 113/784 (14%) Query: 305 VASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPG 364 V +G + G + G PG + G KG+ G PG+PG PGR GP GS PG Sbjct: 801 VGQIGPRGEDGPEGPKGRAGPTGDPGPS-GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPG 859 Query: 365 PPGL------------PCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE 412 PG P P GP GP + G +GP G PG GT G DG PG PGE Sbjct: 860 FPGANGEKGARGVAGKPGPRGQRGPTGP--RGSRGARGPTGKPGPKGTSGGDGPPGPPGE 917 Query: 413 DGKPGDTGPQGFPGTPGDVGPKGDKGDPG-VGERGPPGPQGPPGPPGPSFRHDKLTFIDM 471 G G GP GFPG G GP G G PG G+RG G QG GPPGP + Sbjct: 918 RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG------GVVGP 971 Query: 472 EG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP-------GPAGLPG 523 +G +G G + G RG PGPPGPPG GLPG G+ G P GPAGL G Sbjct: 972 QGPTGETGPI----GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG 1027 Query: 524 VPGREGPPGFPGLPG------PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAG 577 PG G PG G PG P GPPG G PG G G+ G G PG G +G PGPAG Sbjct: 1028 FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG 1087 Query: 578 ARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGG----PFWSTARSADGPQG 633 +G G G GPAG G GP G PGP PAG +G G P ++ G G Sbjct: 1088 EKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1147 Query: 634 PPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPG 693 PPG PGL+G G PG+ G GE G G G G G EG G GP G G +G G PG Sbjct: 1148 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1207 Query: 694 KDG----VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKG---- 745 + G VG G PGPPGP GP +G+ GP+G PG G G G KG Sbjct: 1208 EKGENGDVGPMGPPGPPGPRGP----QGPNGA----DGPQGPPGSVGSVGGVGEKGEPGE 1259 Query: 746 --NLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKG 803 N G GE G GPKGE+GE G P GA GP GAKG PG GP G G G+ G Sbjct: 1260 AGNPGPPGEAGVGGPKGERGEKGEAGPP--GAAGPP--GAKGPPGDDGPKGNPGPVGFPG 1315 Query: 804 EIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAE 863 + G PG PG G +G+ G+KGE GD G PGPPGP G GPPG P Sbjct: 1316 DPGPPGEPGPAGQDGVGGDKGEDGDP-------GQPGPPGPSGEAGPPGPP--------- 1359 Query: 864 SSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGE 923 + GPPG G +G G KGAKGE G GPPG+ Q A G +G RG G GE Sbjct: 1360 -GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGE 1418 Query: 924 RGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGES----------------IRGQPGPP 967 +G PG G G PGP GPPG G G PG KGE +G G P Sbjct: 1419 QGLPGAAGQDGP--PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1476 Query: 968 GPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPH--RQTISVPGP---------PGPPGPP 1015 G QG PG G G GP GP GPPGPP PGP + GP PGPPG P Sbjct: 1477 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP 1536 Query: 1016 GPPG 1019 GPPG Sbjct: 1537 GPPG 1540 Score = 496 bits (1277), Expect = e-140 Identities = 339/846 (40%), Positives = 385/846 (45%), Gaps = 187/846 (22%) Query: 329 PGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPL----------GPA 378 P G G G +G G PG PG GPPG P LPG GLP P + G Sbjct: 446 PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 505 Query: 379 GP------------------ALQTVPGPQ------GPPGPPGRDGTPGRDGEP------- 407 GP AL+ PGP GP G PG G G G+P Sbjct: 506 GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 565 Query: 408 --------GDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV----GERGPPGPQGPPG 455 G PG+ G+PG G +G PG PG G +G G PG+ G RG GPQGPPG Sbjct: 566 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 625 Query: 456 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 515 PPG + I G L GPRG PG PG PG+ G+ G PG G Sbjct: 626 PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKG-----N 680 Query: 516 PGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGP 575 GP G PG PG++G PG GLPGP GP GPPG G +G G AG PG G G PG Sbjct: 681 MGPQGEPGPPGQQGNPGPQGLPGPQGP---IGPPGEKGPQGKPGLAGLPGADGPPGHPGK 737 Query: 576 AGARGESGLAGAPGPAGPPGPPGPPGPPG----------------PGLPAGFDDM--EGS 617 G GE G G PGP GP G PGP G G G P DM +G Sbjct: 738 EGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGD 797 Query: 618 GGPFWSTA-RSADGPQGPPGLPGLKGD---------------PGVPGLPGAKGEVGADGV 661 G R DGP+GP G G GD PG+PG PG +G G+ G Sbjct: 798 RGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 857 Query: 662 PGFPGL------------PGREGIAGPQGPKGDRGSRGEKGDPGKDGV-------GQPGL 702 PGFPG PG G GP GP+G RG+RG G PG G G PG Sbjct: 858 PGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGE 917 Query: 703 PGPPGPPGPVVYVSE--------QDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERG 754 GP GP GPV + +DG + PG G GF G GP GP G +G +G G Sbjct: 918 RGPQGPQGPVGFPGPKGPPGPPGKDG-LPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTG 976 Query: 755 SPGPKGEKGEPGSIFSP-DGGALGPAQK-GAKGEP---GFRGPPGPYGRPGYKGEIGFPG 809 GP GE+G PG P + G G A K GAKG+P G G GP G G+ GE G PG Sbjct: 977 ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 1036 Query: 810 RPGRPGMNGLKGEKGEPGD-------ASLG-FGMRGMPGPPGPPGPPGPPGTPVYDSNVF 861 G PG+ G +G +G PG S G G G+PG PGP GPPGP G Sbjct: 1037 AQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG--------- 1087 Query: 862 AESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQK 921 G PG G QGP G G +G VG PGP G A GE GD+G+ G+ Sbjct: 1088 ----EKGAPGEKGPQGPAGRDGVQGPVGLPGPAG---------PAGSPGEDGDKGEIGEP 1134 Query: 922 GERGEPGGGGFFGSSLPGPPGPPGPRGYPGI------PGPKG----------ESIRGQPG 965 G++G G G G PGPPG GP G PGI PGP+G E RG PG Sbjct: 1135 GQKGSKGDKGENGP--PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1192 Query: 966 PPGP---QGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTM 1021 PPGP QG PG G +G G GP GPPGPP GP GP G GP GPPG++ Sbjct: 1193 PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ-------GPNGADGPQGPPGSV 1245 Query: 1022 GASSGV 1027 G+ GV Sbjct: 1246 GSVGGV 1251 Score = 457 bits (1177), Expect = e-128 Identities = 399/1213 (32%), Positives = 498/1213 (41%), Gaps = 188/1213 (15%) Query: 67 AYVFGPDANSGQVARYHFPS-LFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKL 125 AY A + FP F DFS+LF ++P L +I + G++ Sbjct: 73 AYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYNEH------GIQQ 126 Query: 126 SGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFV-GQWTHLALSVAGGFVALYVDCEEFQ 184 GV+ G + L G FR G+W +A+SV V + VDC++ Sbjct: 127 IGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDCKKKT 186 Query: 185 RMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDS 244 PL RS R + G +F + D + F+G I + + DP+ + +C + D Sbjct: 187 TKPLDRSERAIVDTNGITVFGTRI--LDEEVFEGDIQQFLITGDPKAAYDYC-EHYSPDC 243 Query: 245 DGASGDSGSG-------------------LGDAR----------ELLREETGAALKPRL- 274 D ++ + G+A + EET A + + Sbjct: 244 DSSAPKAAQAQEPQIDEYAPEDIIEYDYEYGEAEYKEAESVTEGPTVTEETIAQTEANIV 303 Query: 275 ---------PAPPPVTTPPLAGGSSTEDSRSEEV--EEQTTVASLGAQ------TLPGSD 317 T P + E + EE+ EE T +Q TL + Sbjct: 304 DDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGEDYDSQRKNSEDTLYENK 363 Query: 318 SVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGP 377 + D + G + + ++ E PP PG P ++ Sbjct: 364 EIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPA-------ETDITETSI 416 Query: 378 AGPALQTVPGPQGPPG--PPGR--DGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGP 433 G G +G P PG +G PG G G G G G TGP PG PGD GP Sbjct: 417 NGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGP---PGDPGDRGP 473 Query: 434 KGDKGDPGV-GERGPPGPQ-------GPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRG 485 G G PG G GPPG G G GP+ I + + L+ R Sbjct: 474 PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPT--------ISAQEAQAQAILQQAR- 524 Query: 486 PRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGR 545 GPPGP G+ G PG G PG +G G G GP G G+ GPPGP G+ Sbjct: 525 -IALRGPPGPMGLTGRPGPVGG--------PGSSGAKGESGDPGPQGPRGVQGPPGPTGK 575 Query: 546 EGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGP 605 G GR G G G G PG KG +G G G G+ G G GP GPPGPPG G G Sbjct: 576 PGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGE 635 Query: 606 GLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFP 665 G + G GP R GP+G PG PG G GV G PG KG +G G PG P Sbjct: 636 DGEIGPRGLPGEAGP-----RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPP 690 Query: 666 GL---PGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSV 722 G PG +G+ GPQGP G G +G +G PG G+ PG GPPG PG E+ Sbjct: 691 GQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGL--PGADGPPGHPGKEGQSGEK--GA 746 Query: 723 LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGP---- 778 L PGP+G G+PGP G KG G +G +GS G KGE G PG F D G G Sbjct: 747 LGPPGPQGP---IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG--FKGDMGLKGDRGEV 801 Query: 779 AQKGAKGEPGFRGP---------PGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPG-- 827 Q G +GE G GP PGP G+ G KG++G PG PG PG G KG G PG Sbjct: 802 GQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFP 861 Query: 828 DASLGFGMRGMPGPPGPPGPPGPPGT--------PVYDSNVFAESSRPGPPGLPGNQGPP 879 A+ G RG+ G PGP G GP G P S GPPG PG +GP Sbjct: 862 GANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQ 921 Query: 880 GPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFG----- 934 GP+G G GP GPPG D L G G RG+ G +G+ G PG GG G Sbjct: 922 GPQGPVGFPGPKGPPGPPGKDGL------PGHPGQRGETGFQGKTGPPGPGGVVGPQGPT 975 Query: 935 --------SSLPGPPGPPGPRGYPGI---------PGPKGES-------IRGQPGP---P 967 PGPPGPPG +G PG PGP+G S +RG PG P Sbjct: 976 GETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLP 1035 Query: 968 GPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGA--S 1024 G QG PG+ G EG QGPPGP G PG G I +PG PGP GPPGP G GA Sbjct: 1036 GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGT-AGPIGLPGRPGPQGPPGPAGEKGAPGE 1094 Query: 1025 SGVRLWATRQAMLGQV----HEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGT 1080 G + A R + G V P G ++ E+ Q G + + E P P G Sbjct: 1095 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1154 Query: 1081 DNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAP-HHSS 1139 V A P + D P PR + + PP Q PG P Sbjct: 1155 QGPVGA---PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGE 1211 Query: 1140 YVHLRPARPTSPP 1152 + P P PP Sbjct: 1212 NGDVGPMGPPGPP 1224 Score = 362 bits (929), Expect = 1e-99 Identities = 236/553 (42%), Positives = 260/553 (47%), Gaps = 103/553 (18%) Query: 309 GAQTLPGSDSVSTWDGSVRT---PGGRVKEG-----GLKGQKGEPGVPGPPGRAGPPGSP 360 GA+ PG +S DG PG R G GLKG +G G PGP G G GS Sbjct: 1006 GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA 1065 Query: 361 CLPGPPGLPCPVSPLGPAGPALQT-VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT 419 GP GLP P GP GPA + PG +GP GP GRDG G G PG G G PG+ Sbjct: 1066 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGED 1125 Query: 420 GPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS-GFGG 478 G +G G PG G KGDKG+ G GPPG QGP G PG + + +G G G Sbjct: 1126 GDKGEIGEPGQKGSKGDKGENG--PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKG 1183 Query: 479 DLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPG 538 D G RGFPGPPGP G+ GLPG PG G N DV GP G PG PG GP G G G Sbjct: 1184 D----EGARGFPGPPGPIGLQGLPGPPGEKGENG-DV-GPMGPPGPPGPRGPQGPNGADG 1237 Query: 539 PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPG 598 P GPPG G G G+KG GEAG PG G G GP G RGE G AG PG AGPPG G Sbjct: 1238 PQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG 1297 Query: 599 PPG------------------PPGPGLPAGFDDMEGS----GGPFWSTARSADGPQGPPG 636 PPG PPG PAG D + G G P G GPPG Sbjct: 1298 PPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG 1357 Query: 637 LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGP----------------- 679 PG +G PG G G +GE GA G G G PG+ G GPQGP Sbjct: 1358 PPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG 1417 Query: 680 -------------------------KGDRGSRGEKGDPGKDGV----------GQPGLPG 704 KGD GS+GEKG PG G+ G GLPG Sbjct: 1418 EQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1477 Query: 705 PPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGS------KGERGSPGP 758 G PG ++ DG + GP G PG G PGP GPKGN GS KG+ G PGP Sbjct: 1478 TQGSPG-----AKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP 1532 Query: 759 KGEKGEPGSIFSP 771 G G PG + P Sbjct: 1533 PGSPGPPGEVIQP 1545 Score = 347 bits (891), Expect = 3e-95 Identities = 226/509 (44%), Positives = 251/509 (49%), Gaps = 84/509 (16%) Query: 279 PVTTPPLAG--GSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPG------ 330 PV P AG GS ED E+ E S G + G G V PG Sbjct: 1109 PVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1168 Query: 331 --GRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP---VSPLGPAGPALQTV 385 G + G+ GQKG+ G G PG GP G LPGPPG V P+GP GP Sbjct: 1169 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP----- 1223 Query: 386 PGPQGPPGPPGRDGT---PGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV 442 PGP+GP GP G DG PG G G GE G+PG+ G G PG G GPKG++G+ G Sbjct: 1224 PGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG- 1282 Query: 443 GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLP 502 E GPPG GPPG GP G D GP+G PGP G PG PG P Sbjct: 1283 -EAGPPGAAGPPGAKGPP----------------GDD-----GPKGNPGPVGFPGDPGPP 1320 Query: 503 GEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAG 562 GEPG PAG GV G +G G PG PGPPGP G GPPG G++G G AG Sbjct: 1321 GEPG-----------PAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAG 1369 Query: 563 APGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFW 622 A G +G KGA G AGA G G G GP GP G PGP G G P G + G+ G Sbjct: 1370 AEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAG--- 1426 Query: 623 STARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGD 682 GP GPPGLPGLKGD PG+KGE G PGL G G G QG KGD Sbjct: 1427 --QDGPPGPMGPPGLPGLKGD------PGSKGE------KGHPGLIGLIGPPGEQGEKGD 1472 Query: 683 RGSRGEKGDPGKDGVGQ-PGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPA 741 RG G +G PG G G PG GP GPPGP +PGP+G G G GPA Sbjct: 1473 RGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP-----------GLPGPQGPKGNKGSTGPA 1521 Query: 742 GPKGNLGSKGERGSPGPKGEKGEPGSIFS 770 G KG+ G G GSPGP GE +P I S Sbjct: 1522 GQKGDSGLPGPPGSPGPPGEVIQPLPILS 1550 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 530 bits (1365), Expect = e-150 Identities = 407/1117 (36%), Positives = 460/1117 (41%), Gaps = 252/1117 (22%) Query: 239 EEGDDSD-GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSE 297 E+G D G G+ G+ R+ E G P P PP PP GG+ Sbjct: 130 EQGPRGDRGDKGEKGAPGPRGRD---GEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGG 186 Query: 298 EVEEQTTVASLGAQTLP-GSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGP 356 +E+ A LG P G G PG + +G G+ GEPGV GP G GP Sbjct: 187 -FDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGN-PGEPGEPGVSGPMGPRGP 244 Query: 357 PGSPCLPGP------PGLPCPVSPLGPAG----PALQTVPGPQGPPGPPGRDGT------ 400 PG P PG PG P GP G P +PG +G G PG DG Sbjct: 245 PGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGA 304 Query: 401 PGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPS 460 PG GE G PGE+G PG GP+G PG G GP G G G G PGP GPPGP GP+ Sbjct: 305 PGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAG--ARGNDGQPGPAGPPGPVGPA 362 Query: 461 FRHDKLTFIDMEGSGFGG--------------DLEALRGPRGFPGPPGPPGVPGLPGEPG 506 G GF G E +GPRG PG PG PG G G PG Sbjct: 363 -----------GGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPG 411 Query: 507 RFGV----NSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAG 562 G+ S+ PG AG PG PG GPPG G GP GP G+ G PG G KG G G Sbjct: 412 TDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKG 471 Query: 563 APGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG------------------ 604 PG G +GAPGPAG G+ G G PG GP GPPG G PG Sbjct: 472 EPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPG 531 Query: 605 ----------------------PGLPA--GFDDMEGSGGPFW----STARSADGPQGPPG 636 PGLP G G GP S A DG GPPG Sbjct: 532 ERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPG 591 Query: 637 LPGLKGDPGVPGLPGAK---------GEVGADGVPGFPGLPGRE---GIAGPQGPKGDRG 684 G +G PGV G PG K GE G G PG GLPG++ G AGP GP G G Sbjct: 592 PQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAG 651 Query: 685 SRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPK 744 RGE+G PG G GLPGPPGPPG + G PG +G PG AG PG GP+ Sbjct: 652 ERGEQGAPGPSGF--QGLPGPPGPPG-------EGGK----PGDQGVPGEAGAPGLVGPR 698 Query: 745 GNLGSKGERGSPGPKGEKGEPGSIFSP--DG--GALGPA-QKGAKGEPGFR--------- 790 G G GERGSPG +G +G G +P DG GA GPA GA+G PG + Sbjct: 699 GERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAA 758 Query: 791 ---------------------------------GPPGPYGRPGYKGEIGFPGRPGRPGMN 817 GPPGP G G KGE+G PG G G Sbjct: 759 GIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGAR 818 Query: 818 GLKGEKGEPG-DASLGF----------------------GMRGMPGPPGPPGPPGPPGT- 853 G GE+GE G GF G G PGP GP G PGP G Sbjct: 819 GAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPT 878 Query: 854 -------------PVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGP------PGPP 894 P + + R GPPG GN GPPGP G G+ GP GPP Sbjct: 879 GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP 938 Query: 895 GQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIP 953 G+ LQ A GEKG+ GD G G G PG G G + G PG G RG+PG+P Sbjct: 939 GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLP 998 Query: 954 GPKGE-------SIRGQPGPPGPQGPPGI----GYEGRQGPPGPPGPPGPPSFPG----- 997 GP GE G GPPGP GPPG+ G GR+G PG GPPG G Sbjct: 999 GPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDR 1058 Query: 998 PHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLG----------QVHEVPEGW 1047 + PG PGPPG PGP G G G R A Q +G Q + P G Sbjct: 1059 GETGAVGAPGAPGPPGSPGPAGPTG-KQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGD 1117 Query: 1048 LIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQP-----PVVQLHDSNPYPR 1102 E E ++ GF +Q P P G P P + S Sbjct: 1118 KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGA 1177 Query: 1103 REHPHPTARPW----RADDILASPPRLPEPQPYPGAP 1135 P P P + A PP P P PG P Sbjct: 1178 NGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPP 1214 Score = 528 bits (1361), Expect = e-149 Identities = 351/888 (39%), Positives = 407/888 (45%), Gaps = 163/888 (18%) Query: 250 DSGSGLGDARELLREETGAALKPRLPAPP--PVTTPPLAGGSSTEDSRSEEVEEQTTVAS 307 D+G+ L D +++ E+ L P +P P+ LA S + ++ E Sbjct: 58 DTGTVLCD--DIICEDVKDCLSPEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDI 115 Query: 308 LGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPG 367 +G + PG P G G +G KGE G PGP GR G PG+P PGPPG Sbjct: 116 VGPKGPPGPQG----------PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPG 165 Query: 368 LPCPVSP---------------------------LGPAGPALQTVPGPQGPPGPPGRDGT 400 P P P GP GP GP+GPPGP G G Sbjct: 166 PPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM-----GPRGPPGPAGAPGP 220 Query: 401 PGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPG-VGERGPPGPQGP---PGP 456 G G PG+PGE G G GP+G PG PG G G+ G PG GERGPPGPQG PG Sbjct: 221 QGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGT 280 Query: 457 PGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFP---GPPGPPGVPGLPGEPGRFGV--- 510 PG + ++G+ ++G G P G PGP G GLPGE GR G Sbjct: 281 PGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGA 340 Query: 511 ----NSSDVPGPAGLPGVPGREGPPGFPGLPGPP---------GPPGREGPPGRTGQKGS 557 + PGPAG PG G G PGFPG PG GP G +GP G G GS Sbjct: 341 AGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGS 400 Query: 558 LGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLP------AGF 611 G AGA G+ G+ G PG G+ G G+AGAPG GP GPPGP G GP P G Sbjct: 401 PGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGI 460 Query: 612 DDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGAD---GVPGFPGLP 668 +G GP + GPQG PG G +G G G PG G +G G PG G P Sbjct: 461 AGFKGEQGPKGEPGPA--GPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFP 518 Query: 669 GREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQ-DGSVLSVPG 727 G++G+AGP+G G+RG G G G + G PG PG PG PG D G Sbjct: 519 GQDGLAGPKGAPGERGPSGLAGPKGAN--GDPGRPGEPGLPGARGLTGRPGDAGPQGKVG 576 Query: 728 PEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEP 787 P G PG G PGP GP+G G G G PGPKG GEPG GE Sbjct: 577 PSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGK----------------AGEK 620 Query: 788 GFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGP 847 G G PG G PG GE G G PG G G +GE+G PG + G +G+PGPPGPPG Sbjct: 621 GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPS----GFQGLPGPPGPPGE 676 Query: 848 PGPPGTPVYDSNVFAESSRP------------------------GPPGLPGNQGPPGPKG 883 G PG D V E+ P GP GLPG G GPKG Sbjct: 677 GGKPG----DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKG 732 Query: 884 AKGEVGPP---GPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGP 940 A G GPP GPPG + A + G KGDRGD G+KG G PG G G L GP Sbjct: 733 ASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDG--GRGLTGP 790 Query: 941 PGPPGP------RGYPGIPGPKGES-------IRGQPGPPGP---QGPPGI--------- 975 GPPGP +G G PGP G + RG+ GPPGP GPPG Sbjct: 791 IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGE 850 Query: 976 -GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1022 G G++G G PGP GP PGP T V GP G G GPPG G Sbjct: 851 QGEAGQKGDAGAPGPQGPSGAPGPQGPT-GVTGPKGARGAQGPPGATG 897 Score = 518 bits (1334), Expect = e-146 Identities = 331/766 (43%), Positives = 374/766 (48%), Gaps = 99/766 (12%) Query: 309 GAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGL 368 G + PG D ++ G PG R GL G KG G PG PG G PG+ L G PG Sbjct: 513 GNRGFPGQDGLA---GPKGAPGER-GPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGD 568 Query: 369 PCPVSPLGPAG-PALQTVPGPQGP------------PGPPGRDGTPGRDGE---PGDPGE 412 P +GP+G P PGP GP PGP G +G PG+ GE PG PG Sbjct: 569 AGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL 628 Query: 413 DGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDME 472 G PG G G G PG GP G++G+ G GP G QG PGPPGP K + Sbjct: 629 RGLPGKDGETGAAGPPGPAGPAGERGEQGAP--GPSGFQGLPGPPGPPGEGGKPGDQGVP 686 Query: 473 GSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP-GPAGLPGVPGREGPP 531 G L RG RGFPG G PG GL G G G +D P G +G G PG +GPP Sbjct: 687 GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPP 746 Query: 532 GFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA------PGPAGARGESGLA 585 G G+PG G G GP G G G G GAPG G +G PGPAGA GE G Sbjct: 747 GLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEV 806 Query: 586 GAPGPAGPPGP---------PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSAD----GPQ 632 G PGPAG G GPPGP G P G D G+ G + D GPQ Sbjct: 807 GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 866 Query: 633 GPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGR---------EGIAGPQGPKGDR 683 GP G PG +G GV G GA+G G G GFPG GR G GP GP G Sbjct: 867 GPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKD 926 Query: 684 GSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAG 742 G +G +GD G G G+PGL GP GPPG G G G +G GP G Sbjct: 927 GPKGARGDSGPPGRAGEPGLQGPAGPPGE--------------KGEPGDDGPSGAEGPPG 972 Query: 743 PKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYK 802 P+G G +G G PG +GE+G PG + P G P ++GA G G RGPPGP G PG Sbjct: 973 PQGLAGQRGIVGLPGQRGERGFPG-LPGPSGE---PGKQGAPGASGDRGPPGPVGPPGLT 1028 Query: 803 GEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFA 862 G G PGR G PG +G G G G G RG G G PG PGPPG+P Sbjct: 1029 GPAGEPGREGSPGADGPPGRDGAAGVK----GDRGETGAVGAPGAPGPPGSP-------- 1076 Query: 863 ESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKG 922 GP G G QG G GA+G +GP GP G Q G +GD+G+AG+ G Sbjct: 1077 -----GPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQ------GPRGDKGEAGEPG 1125 Query: 923 ERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI-GYEGRQ 981 ERG G GF G L G PGPPGP G G GP G S G GPPGP GP G G G Sbjct: 1126 ERGLKGHRGFTG--LQGLPGPPGPSGDQGASGPAGPS--GPRGPPGPVGPSGKDGANGIP 1181 Query: 982 GPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGV 1027 GP GPPGP G GP + PGPPGPPGPPGP M A +G+ Sbjct: 1182 GPIGPPGPRGRSGETGPAGPPGN-PGPPGPPGPPGPGIDMSAFAGL 1226 Score = 404 bits (1037), Expect = e-112 Identities = 280/742 (37%), Positives = 332/742 (44%), Gaps = 114/742 (15%) Query: 246 GASGDSGS----GLGDARELLREE-----------TGAALKPRLPAPPPVT----TPPLA 286 GA+GD G GL AR L +GA + P PP P + Sbjct: 543 GANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVM 602 Query: 287 GGSSTEDSRSE--EVEEQTTVASLGAQTLPGSDS---VSTWDGSVRTPGGRVKEG--GLK 339 G + + E + E+ + G + LPG D + G G R ++G G Sbjct: 603 GFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPS 662 Query: 340 GQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG-PALQTVPGPQGPPGPPGRD 398 G +G PG PGPPG G PG +PG G P V P G G P + PG QG GP G Sbjct: 663 GFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP 722 Query: 399 GTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGD------VGPKGDKGDPGVGERGPPGPQG 452 GTPG DG G G G PG GP G G PG+ GPKGD+GD VGE+GP G G Sbjct: 723 GTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD--VGEKGPEGAPG 780 Query: 453 ---------PPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPG 503 P GPPGP+ + + + G G RG GPPGP G G PG Sbjct: 781 KDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPG 840 Query: 504 EPGRFGVNSSD----------VPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTG 553 G+ G PGP G G PG +GP G + GP G G +GPPG TG Sbjct: 841 ADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTG---VTGPKGARGAQGPPGATG 897 Query: 554 QKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDD 613 G+ G G PG G+ G PGP G G+ G GA G +GPPG G PG GP P G Sbjct: 898 FPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG 957 Query: 614 MEGSGGPFWSTARSADGPQGPPG------LPGLKGDPGVPGLPGAKGEVGADGVPGF--- 664 G GP S A GPQG G LPG +G+ G PGLPG GE G G PG Sbjct: 958 EPGDDGP--SGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGD 1015 Query: 665 ---------PGL------PGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGP 708 PGL PGREG G GP G G+ G KGD G+ G VG PG PGPPG Sbjct: 1016 RGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS 1075 Query: 709 PGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSI 768 PGP G +G G AG GP GP G G++G +G GP+G+KGE G Sbjct: 1076 PGPA-----------GPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGE- 1123 Query: 769 FSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGD 828 P ++G KG GF G G G PG G+ G G G G G G G G Sbjct: 1124 ---------PGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGK 1174 Query: 829 ASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEV 888 G G+PGP GPPGP G G ++ PGPPG PG GP A + Sbjct: 1175 D----GANGIPGPIGPPGPRGRSG----ETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGL 1226 Query: 889 GPPGPPGQFPFDFLQLEAEMKG 910 G P G P +++ + G Sbjct: 1227 G-PREKGPDPLQYMRADQAAGG 1247 Score = 372 bits (955), Expect = e-102 Identities = 258/648 (39%), Positives = 293/648 (45%), Gaps = 105/648 (16%) Query: 242 DDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEE 301 D GA+G G G A E R E GA P PP GG + E Sbjct: 635 DGETGAAGPPGPA-GPAGE--RGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA 691 Query: 302 QTTVA------------SLGAQTL---------PGSDSVSTWDGSVRTPGGRVKEG--GL 338 V S GAQ L PG+D G PG + G G+ Sbjct: 692 PGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGM 751 Query: 339 KGQKGEPGVPGPPG------RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPP 392 G++G G+ GP G GP G+P G GL P+ P GPAG G +G Sbjct: 752 PGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAG-----ANGEKGEV 806 Query: 393 GPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQ 451 GPPG G+ G G PG+ GE G PG G G PG G G KG++G+ G G+ G PGPQ Sbjct: 807 GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 866 Query: 452 GP---PGPPGPSFRHDKLTFIDMEG----SGFGGDLEALRGPRGFPGPPGPPGVPGLPGE 504 GP PGP GP+ +G +GF G + GP G G PGPPG PG G+ Sbjct: 867 GPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRV-GPPGSNGNPGPPGPPGPSGK 925 Query: 505 PGRFGVNS-SDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGA 563 G G S PG AG PG+ G GPPG G PG GP G EGPPG G G G G Sbjct: 926 DGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGL 985 Query: 564 PGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWS 623 PG +G +G PG G GE G GAPG +G GPPGP GPPG PAG EGS G Sbjct: 986 PGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPG---- 1041 Query: 624 TARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDR 683 ADGP G G G+KGD +GE GA G PG PG PG G AGP G +GDR Sbjct: 1042 ----ADGPPGRDGAAGVKGD---------RGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1088 Query: 684 GSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAG 742 G G +G G G G G+ GP GP G E L G G G G PGP G Sbjct: 1089 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLK--GHRGFTGLQGLPGPPG 1146 Query: 743 PKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYK 802 P G+ G+ G G GP+G G G P G + GA G PG GPPGP GR G Sbjct: 1147 PSGDQGASGPAGPSGPRGPPGPVG----PSG------KDGANGIPGPIGPPGPRGRSGET 1196 Query: 803 GEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGP 850 G G PG P GPPGPPGPPGP Sbjct: 1197 GPAGPPGNP----------------------------GPPGPPGPPGP 1216 Score = 234 bits (598), Expect = 3e-61 Identities = 164/461 (35%), Positives = 188/461 (40%), Gaps = 58/461 (12%) Query: 246 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 305 G G +GS R ETG P P PP A G E ++ Sbjct: 807 GPPGPAGSAGARGAPGERGETGP------PGPAGFAGPPGADGQPGAKGEQGEAGQKGDA 860 Query: 306 ASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGP 365 + G Q G+ G G R G +G G G PG GR GPPGS PGP Sbjct: 861 GAPGPQGPSGAPGPQGPTGVTGPKGAR----GAQGPPGATGFPGAAGRVGPPGSNGNPGP 916 Query: 366 PGLPCPVSPLGPAG-------PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGK--- 415 PG P P GP G P PG QGP GPPG G PG DG G G G Sbjct: 917 PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 976 Query: 416 ---------PGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDK 465 PG G +GFPG PG G G +G PG G+RGPPGP GPPG GP+ + Sbjct: 977 AGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGR 1036 Query: 466 LTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSD----------- 514 +G ++G RG G G PG PG PG PG G Sbjct: 1037 EGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1096 Query: 515 --VPGPAGLPGVPGREGP---------PGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGA 563 GPAG G+ G +GP PG GL G G G +G PG G G G +G Sbjct: 1097 MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP 1156 Query: 564 PGHKGSKGAPGPAGARGESGLAGAPGPAGPPGP------PGPPGPPGPGLPAGFDDMEGS 617 G G +G PGP G G+ G G PGP GPPGP GP GPPG P G G Sbjct: 1157 AGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGP 1216 Query: 618 GGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGA 658 G + A +GP L ++ D GL EV A Sbjct: 1217 GIDMSAFAGLGPREKGPDPLQYMRADQAAGGLRQHDAEVDA 1257 Score = 88.6 bits (218), Expect = 4e-17 Identities = 79/244 (32%), Positives = 92/244 (37%), Gaps = 49/244 (20%) Query: 916 GDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI 975 G G KG++GEPG + GP GPPGP+G G GP+G+ RG G G GP Sbjct: 98 GQPGPKGQKGEPGDI----KDIVGPKGPPGPQGPAGEQGPRGD--RGDKGEKGAPGP--- 148 Query: 976 GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQA 1035 GR G PG PG PGPP GPPGPPGPPG G A Sbjct: 149 --RGRDGEPGTPGNPGPP-------------GPPGPPGPPGLGGNFAAQ----------- 182 Query: 1036 MLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLH 1095 M G E G + V + G R A P P+G P V Sbjct: 183 MAGGFDEKAGGAQLGVMQGP----MGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGV--- 235 Query: 1096 DSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHS 1155 S P R P P +P DD A P + PG + P P P Sbjct: 236 -SGPMGPRGPPGPPGKP--GDDGEAGKPGKAGERGPPGPQGARGF----PGTPGLPGVKG 288 Query: 1156 HRDF 1159 HR + Sbjct: 289 HRGY 292 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 530 bits (1365), Expect = e-150 Identities = 407/1117 (36%), Positives = 460/1117 (41%), Gaps = 252/1117 (22%) Query: 239 EEGDDSD-GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSE 297 E+G D G G+ G+ R+ E G P P PP PP GG+ Sbjct: 61 EQGPRGDRGDKGEKGAPGPRGRD---GEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGG 117 Query: 298 EVEEQTTVASLGAQTLP-GSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGP 356 +E+ A LG P G G PG + +G G+ GEPGV GP G GP Sbjct: 118 -FDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGN-PGEPGEPGVSGPMGPRGP 175 Query: 357 PGSPCLPGP------PGLPCPVSPLGPAG----PALQTVPGPQGPPGPPGRDGT------ 400 PG P PG PG P GP G P +PG +G G PG DG Sbjct: 176 PGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGA 235 Query: 401 PGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPS 460 PG GE G PGE+G PG GP+G PG G GP G G G G PGP GPPGP GP+ Sbjct: 236 PGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAG--ARGNDGQPGPAGPPGPVGPA 293 Query: 461 FRHDKLTFIDMEGSGFGG--------------DLEALRGPRGFPGPPGPPGVPGLPGEPG 506 G GF G E +GPRG PG PG PG G G PG Sbjct: 294 -----------GGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPG 342 Query: 507 RFGV----NSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAG 562 G+ S+ PG AG PG PG GPPG G GP GP G+ G PG G KG G G Sbjct: 343 TDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKG 402 Query: 563 APGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG------------------ 604 PG G +GAPGPAG G+ G G PG GP GPPG G PG Sbjct: 403 EPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPG 462 Query: 605 ----------------------PGLPA--GFDDMEGSGGPFW----STARSADGPQGPPG 636 PGLP G G GP S A DG GPPG Sbjct: 463 ERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPG 522 Query: 637 LPGLKGDPGVPGLPGAK---------GEVGADGVPGFPGLPGRE---GIAGPQGPKGDRG 684 G +G PGV G PG K GE G G PG GLPG++ G AGP GP G G Sbjct: 523 PQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAG 582 Query: 685 SRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPK 744 RGE+G PG G GLPGPPGPPG + G PG +G PG AG PG GP+ Sbjct: 583 ERGEQGAPGPSGF--QGLPGPPGPPG-------EGGK----PGDQGVPGEAGAPGLVGPR 629 Query: 745 GNLGSKGERGSPGPKGEKGEPGSIFSP--DG--GALGPA-QKGAKGEPGFR--------- 790 G G GERGSPG +G +G G +P DG GA GPA GA+G PG + Sbjct: 630 GERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAA 689 Query: 791 ---------------------------------GPPGPYGRPGYKGEIGFPGRPGRPGMN 817 GPPGP G G KGE+G PG G G Sbjct: 690 GIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGAR 749 Query: 818 GLKGEKGEPG-DASLGF----------------------GMRGMPGPPGPPGPPGPPGT- 853 G GE+GE G GF G G PGP GP G PGP G Sbjct: 750 GAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPT 809 Query: 854 -------------PVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGP------PGPP 894 P + + R GPPG GN GPPGP G G+ GP GPP Sbjct: 810 GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP 869 Query: 895 GQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIP 953 G+ LQ A GEKG+ GD G G G PG G G + G PG G RG+PG+P Sbjct: 870 GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLP 929 Query: 954 GPKGE-------SIRGQPGPPGPQGPPGI----GYEGRQGPPGPPGPPGPPSFPG----- 997 GP GE G GPPGP GPPG+ G GR+G PG GPPG G Sbjct: 930 GPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDR 989 Query: 998 PHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLG----------QVHEVPEGW 1047 + PG PGPPG PGP G G G R A Q +G Q + P G Sbjct: 990 GETGAVGAPGAPGPPGSPGPAGPTG-KQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGD 1048 Query: 1048 LIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQP-----PVVQLHDSNPYPR 1102 E E ++ GF +Q P P G P P + S Sbjct: 1049 KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGA 1108 Query: 1103 REHPHPTARPW----RADDILASPPRLPEPQPYPGAP 1135 P P P + A PP P P PG P Sbjct: 1109 NGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPP 1145 Score = 523 bits (1347), Expect = e-148 Identities = 335/807 (41%), Positives = 378/807 (46%), Gaps = 149/807 (18%) Query: 329 PGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSP-------------- 374 P G G +G KGE G PGP GR G PG+P PGPPG P P P Sbjct: 58 PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGG 117 Query: 375 -------------LGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGP 421 GP GP GP+GPPGP G G G G PG+PGE G G GP Sbjct: 118 FDEKAGGAQLGVMQGPMGPM-----GPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGP 172 Query: 422 QGFPGTPGDVGPKGDKGDPG-VGERGPPGPQGP---PGPPGPSFRHDKLTFIDMEGSGFG 477 +G PG PG G G+ G PG GERGPPGPQG PG PG + ++G+ Sbjct: 173 RGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGE 232 Query: 478 GDLEALRGPRGFP---GPPGPPGVPGLPGEPGRFGV-------NSSDVPGPAGLPGVPGR 527 ++G G P G PGP G GLPGE GR G + PGPAG PG G Sbjct: 233 AGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGP 292 Query: 528 EGPPGFPGLPGPP---------GPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGA 578 G PGFPG PG GP G +GP G G GS G AGA G+ G+ G PG G+ Sbjct: 293 AGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGS 352 Query: 579 RGESGLAGAPGPAGPPGPPGPPGPPGPGLP------AGFDDMEGSGGPFWSTARSADGPQ 632 G G+AGAPG GP GPPGP G GP P G +G GP + GPQ Sbjct: 353 AGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPA--GPQ 410 Query: 633 GPPGLPGLKGDPGVPGLPGAKGEVGAD---GVPGFPGLPGREGIAGPQGPKGDRGSRGEK 689 G PG G +G G G PG G +G G PG G PG++G+AGP+G G+RG G Sbjct: 411 GAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLA 470 Query: 690 GDPGKDGVGQPGLPGPPGPPGPVVYVSEQ-DGSVLSVPGPEGRPGFAGFPGPAGPKGNLG 748 G G + G PG PG PG PG D GP G PG G PGP GP+G G Sbjct: 471 GPKGAN--GDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARG 528 Query: 749 SKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFP 808 G G PGPKG GEPG GE G G PG G PG GE G Sbjct: 529 QPGVMGFPGPKGANGEPGK----------------AGEKGLPGAPGLRGLPGKDGETGAA 572 Query: 809 GRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRP- 867 G PG G G +GE+G PG + G +G+PGPPGPPG G PG D V E+ P Sbjct: 573 GPPGPAGPAGERGEQGAPGPS----GFQGLPGPPGPPGEGGKPG----DQGVPGEAGAPG 624 Query: 868 -----------------------GPPGLPGNQGPPGPKGAKGEVGPP---GPPGQFPFDF 901 GP GLPG G GPKGA G GPP GPPG Sbjct: 625 LVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPG 684 Query: 902 LQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGP------RGYPGIPGP 955 + A + G KGDRGD G+KG G PG G G L GP GPPGP +G G PGP Sbjct: 685 ERGAAGIAGPKGDRGDVGEKGPEGAPGKDG--GRGLTGPIGPPGPAGANGEKGEVGPPGP 742 Query: 956 KGES-------IRGQPGPPGP---QGPPGI----------GYEGRQGPPGPPGPPGPPSF 995 G + RG+ GPPGP GPPG G G++G G PGP GP Sbjct: 743 AGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGA 802 Query: 996 PGPHRQTISVPGPPGPPGPPGPPGTMG 1022 PGP T V GP G G GPPG G Sbjct: 803 PGPQGPT-GVTGPKGARGAQGPPGATG 828 Score = 518 bits (1334), Expect = e-146 Identities = 331/766 (43%), Positives = 374/766 (48%), Gaps = 99/766 (12%) Query: 309 GAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGL 368 G + PG D ++ G PG R GL G KG G PG PG G PG+ L G PG Sbjct: 444 GNRGFPGQDGLA---GPKGAPGER-GPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGD 499 Query: 369 PCPVSPLGPAG-PALQTVPGPQGP------------PGPPGRDGTPGRDGE---PGDPGE 412 P +GP+G P PGP GP PGP G +G PG+ GE PG PG Sbjct: 500 AGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL 559 Query: 413 DGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDME 472 G PG G G G PG GP G++G+ G GP G QG PGPPGP K + Sbjct: 560 RGLPGKDGETGAAGPPGPAGPAGERGEQGAP--GPSGFQGLPGPPGPPGEGGKPGDQGVP 617 Query: 473 GSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP-GPAGLPGVPGREGPP 531 G L RG RGFPG G PG GL G G G +D P G +G G PG +GPP Sbjct: 618 GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPP 677 Query: 532 GFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA------PGPAGARGESGLA 585 G G+PG G G GP G G G G GAPG G +G PGPAGA GE G Sbjct: 678 GLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEV 737 Query: 586 GAPGPAGPPGP---------PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSAD----GPQ 632 G PGPAG G GPPGP G P G D G+ G + D GPQ Sbjct: 738 GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 797 Query: 633 GPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGR---------EGIAGPQGPKGDR 683 GP G PG +G GV G GA+G G G GFPG GR G GP GP G Sbjct: 798 GPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKD 857 Query: 684 GSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAG 742 G +G +GD G G G+PGL GP GPPG G G G +G GP G Sbjct: 858 GPKGARGDSGPPGRAGEPGLQGPAGPPGE--------------KGEPGDDGPSGAEGPPG 903 Query: 743 PKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYK 802 P+G G +G G PG +GE+G PG + P G P ++GA G G RGPPGP G PG Sbjct: 904 PQGLAGQRGIVGLPGQRGERGFPG-LPGPSGE---PGKQGAPGASGDRGPPGPVGPPGLT 959 Query: 803 GEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFA 862 G G PGR G PG +G G G G G RG G G PG PGPPG+P Sbjct: 960 GPAGEPGREGSPGADGPPGRDGAAGVK----GDRGETGAVGAPGAPGPPGSP-------- 1007 Query: 863 ESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKG 922 GP G G QG G GA+G +GP GP G Q G +GD+G+AG+ G Sbjct: 1008 -----GPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQ------GPRGDKGEAGEPG 1056 Query: 923 ERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI-GYEGRQ 981 ERG G GF G L G PGPPGP G G GP G S G GPPGP GP G G G Sbjct: 1057 ERGLKGHRGFTG--LQGLPGPPGPSGDQGASGPAGPS--GPRGPPGPVGPSGKDGANGIP 1112 Query: 982 GPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGV 1027 GP GPPGP G GP + PGPPGPPGPPGP M A +G+ Sbjct: 1113 GPIGPPGPRGRSGETGPAGPPGN-PGPPGPPGPPGPGIDMSAFAGL 1157 Score = 404 bits (1037), Expect = e-112 Identities = 280/742 (37%), Positives = 332/742 (44%), Gaps = 114/742 (15%) Query: 246 GASGDSGS----GLGDARELLREE-----------TGAALKPRLPAPPPVT----TPPLA 286 GA+GD G GL AR L +GA + P PP P + Sbjct: 474 GANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVM 533 Query: 287 GGSSTEDSRSE--EVEEQTTVASLGAQTLPGSDS---VSTWDGSVRTPGGRVKEG--GLK 339 G + + E + E+ + G + LPG D + G G R ++G G Sbjct: 534 GFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPS 593 Query: 340 GQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG-PALQTVPGPQGPPGPPGRD 398 G +G PG PGPPG G PG +PG G P V P G G P + PG QG GP G Sbjct: 594 GFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP 653 Query: 399 GTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGD------VGPKGDKGDPGVGERGPPGPQG 452 GTPG DG G G G PG GP G G PG+ GPKGD+GD VGE+GP G G Sbjct: 654 GTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD--VGEKGPEGAPG 711 Query: 453 ---------PPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPG 503 P GPPGP+ + + + G G RG GPPGP G G PG Sbjct: 712 KDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPG 771 Query: 504 EPGRFGVNSSD----------VPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTG 553 G+ G PGP G G PG +GP G + GP G G +GPPG TG Sbjct: 772 ADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTG---VTGPKGARGAQGPPGATG 828 Query: 554 QKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDD 613 G+ G G PG G+ G PGP G G+ G GA G +GPPG G PG GP P G Sbjct: 829 FPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG 888 Query: 614 MEGSGGPFWSTARSADGPQGPPG------LPGLKGDPGVPGLPGAKGEVGADGVPGF--- 664 G GP S A GPQG G LPG +G+ G PGLPG GE G G PG Sbjct: 889 EPGDDGP--SGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGD 946 Query: 665 ---------PGL------PGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGP 708 PGL PGREG G GP G G+ G KGD G+ G VG PG PGPPG Sbjct: 947 RGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS 1006 Query: 709 PGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSI 768 PGP G +G G AG GP GP G G++G +G GP+G+KGE G Sbjct: 1007 PGPA-----------GPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGE- 1054 Query: 769 FSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGD 828 P ++G KG GF G G G PG G+ G G G G G G G G Sbjct: 1055 ---------PGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGK 1105 Query: 829 ASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEV 888 G G+PGP GPPGP G G ++ PGPPG PG GP A + Sbjct: 1106 D----GANGIPGPIGPPGPRGRSG----ETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGL 1157 Query: 889 GPPGPPGQFPFDFLQLEAEMKG 910 G P G P +++ + G Sbjct: 1158 G-PREKGPDPLQYMRADQAAGG 1178 Score = 376 bits (966), Expect = e-104 Identities = 251/624 (40%), Positives = 277/624 (44%), Gaps = 162/624 (25%) Query: 522 PGVPGREGPPG-FPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARG 580 PG G++G PG + GP GPPG +GP G G +G G+ KG KGAPGP G G Sbjct: 31 PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGD------KGEKGAPGPRGRDG 84 Query: 581 ESGLAGAPGPAGPPGPPGPP------------------------------------GPPG 604 E G G PGP GPPGPPGPP GPPG Sbjct: 85 EPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPG 144 Query: 605 PG---LPAGFDDMEG----------------------------SGGPFWSTARSADGPQ- 632 P P GF G +G P + R GPQ Sbjct: 145 PAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQG 204 Query: 633 -----GPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRG 687 G PGLPG+KG G PGL GAKGE GA GV G G PG G GP GP+G G RG Sbjct: 205 ARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERG 264 Query: 688 EKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGN 746 G G G G G PGP GPPGPV GP G PGF G PG G G Sbjct: 265 RTGPAGAAGARGNDGQPGPAGPPGPV--------------GPAGGPGFPGAPGAKGEAGP 310 Query: 747 LGSKGERGSPGPKGEKGEPGS--------------IFSPDGGALGPAQKGAKGEPGFRGP 792 G++G G+ GP+GE G PGS I G A P GA G PG RGP Sbjct: 311 TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP 370 Query: 793 PGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASL-----------GFGMRGMPGP 841 PGP G G G G G PG G G +G KGEPG A G RG PG Sbjct: 371 PGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGG 430 Query: 842 PGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGP---PGPKGAKGEVGPPGPPGQFP 898 GP GPPG G P + + GP G PG +GP GPKGA G+ G PG PG Sbjct: 431 VGPIGPPGERGAP-GNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPG--- 486 Query: 899 FDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGI---PGP 955 L + G GD G G+ G G PG G PGPPGP G RG PG+ PGP Sbjct: 487 ---LPGARGLTGRPGDAGPQGKVGPSGAPGEDG-----RPGPPGPQGARGQPGVMGFPGP 538 Query: 956 KGES-------IRGQPGPPGPQGPPG-IGYEGRQGPPGPPGP---------PGPPSFPGP 998 KG + +G PG PG +G PG G G GPPGP GP PGP F G Sbjct: 539 KGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQG- 597 Query: 999 HRQTISVPGPPGPPGPPGPPGTMG 1022 +PGPPGPPG G PG G Sbjct: 598 ------LPGPPGPPGEGGKPGDQG 615 Score = 372 bits (955), Expect = e-102 Identities = 258/648 (39%), Positives = 293/648 (45%), Gaps = 105/648 (16%) Query: 242 DDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEE 301 D GA+G G G A E R E GA P PP GG + E Sbjct: 566 DGETGAAGPPGPA-GPAGE--RGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA 622 Query: 302 QTTVA------------SLGAQTL---------PGSDSVSTWDGSVRTPGGRVKEG--GL 338 V S GAQ L PG+D G PG + G G+ Sbjct: 623 PGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGM 682 Query: 339 KGQKGEPGVPGPPG------RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPP 392 G++G G+ GP G GP G+P G GL P+ P GPAG G +G Sbjct: 683 PGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAG-----ANGEKGEV 737 Query: 393 GPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQ 451 GPPG G+ G G PG+ GE G PG G G PG G G KG++G+ G G+ G PGPQ Sbjct: 738 GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 797 Query: 452 GP---PGPPGPSFRHDKLTFIDMEG----SGFGGDLEALRGPRGFPGPPGPPGVPGLPGE 504 GP PGP GP+ +G +GF G + GP G G PGPPG PG G+ Sbjct: 798 GPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRV-GPPGSNGNPGPPGPPGPSGK 856 Query: 505 PGRFGVNS-SDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGA 563 G G S PG AG PG+ G GPPG G PG GP G EGPPG G G G G Sbjct: 857 DGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGL 916 Query: 564 PGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWS 623 PG +G +G PG G GE G GAPG +G GPPGP GPPG PAG EGS G Sbjct: 917 PGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPG---- 972 Query: 624 TARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDR 683 ADGP G G G+KGD +GE GA G PG PG PG G AGP G +GDR Sbjct: 973 ----ADGPPGRDGAAGVKGD---------RGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1019 Query: 684 GSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAG 742 G G +G G G G G+ GP GP G E L G G G G PGP G Sbjct: 1020 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLK--GHRGFTGLQGLPGPPG 1077 Query: 743 PKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYK 802 P G+ G+ G G GP+G G G P G + GA G PG GPPGP GR G Sbjct: 1078 PSGDQGASGPAGPSGPRGPPGPVG----PSG------KDGANGIPGPIGPPGPRGRSGET 1127 Query: 803 GEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGP 850 G G PG P GPPGPPGPPGP Sbjct: 1128 GPAGPPGNP----------------------------GPPGPPGPPGP 1147 Score = 234 bits (598), Expect = 3e-61 Identities = 164/461 (35%), Positives = 188/461 (40%), Gaps = 58/461 (12%) Query: 246 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 305 G G +GS R ETG P P PP A G E ++ Sbjct: 738 GPPGPAGSAGARGAPGERGETGP------PGPAGFAGPPGADGQPGAKGEQGEAGQKGDA 791 Query: 306 ASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGP 365 + G Q G+ G G R G +G G G PG GR GPPGS PGP Sbjct: 792 GAPGPQGPSGAPGPQGPTGVTGPKGAR----GAQGPPGATGFPGAAGRVGPPGSNGNPGP 847 Query: 366 PGLPCPVSPLGPAG-------PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGK--- 415 PG P P GP G P PG QGP GPPG G PG DG G G G Sbjct: 848 PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 907 Query: 416 ---------PGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDK 465 PG G +GFPG PG G G +G PG G+RGPPGP GPPG GP+ + Sbjct: 908 AGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGR 967 Query: 466 LTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSD----------- 514 +G ++G RG G G PG PG PG PG G Sbjct: 968 EGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1027 Query: 515 --VPGPAGLPGVPGREGP---------PGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGA 563 GPAG G+ G +GP PG GL G G G +G PG G G G +G Sbjct: 1028 MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP 1087 Query: 564 PGHKGSKGAPGPAGARGESGLAGAPGPAGPPGP------PGPPGPPGPGLPAGFDDMEGS 617 G G +G PGP G G+ G G PGP GPPGP GP GPPG P G G Sbjct: 1088 AGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGP 1147 Query: 618 GGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGA 658 G + A +GP L ++ D GL EV A Sbjct: 1148 GIDMSAFAGLGPREKGPDPLQYMRADQAAGGLRQHDAEVDA 1188 Score = 99.0 bits (245), Expect = 3e-20 Identities = 58/148 (39%), Positives = 74/148 (50%), Gaps = 20/148 (13%) Query: 892 GPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPG 951 G P L + A ++ + D G KG++GEPG + GP GPPGP+G G Sbjct: 5 GAPQTLVLLTLLVAAVLRCQGQDVRQPGPKGQKGEPGD----IKDIVGPKGPPGPQGPAG 60 Query: 952 IPGPKGE-SIRGQPGPPGPQGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTIS----- 1004 GP+G+ +G+ G PGP+G G G G GPPGPPGPPGPP G ++ Sbjct: 61 EQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDE 120 Query: 1005 ---------VPGPPGPPGPPGPPGTMGA 1023 + GP GP GP GPPG GA Sbjct: 121 KAGGAQLGVMQGPMGPMGPRGPPGPAGA 148 >gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo sapiens] Length = 1629 Score = 528 bits (1359), Expect = e-149 Identities = 387/1039 (37%), Positives = 474/1039 (45%), Gaps = 161/1039 (15%) Query: 66 LAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIR--PATEGPGVLFAITDSAQAMVLLGV 123 +AY A R FP F +DFSLL +R P + P + SAQ + LG+ Sbjct: 58 VAYRVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLY---SAQGVRQLGL 114 Query: 124 KLSGVQDGHQDISLLYTEP-GAGQTHTAASFR-LPAFVGQWTHLALSVAGGFVALYVDCE 181 +L + + LY + G Q + FR L G+W +A++V G V L VDC+ Sbjct: 115 ELG------RPVRFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCK 168 Query: 182 EFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEG 241 + PL RS+R + G +F A+ D + F+G + EL + Q + C +E Sbjct: 169 KRVTRPLPRSARPVLDTHGVIIFGARI--LDEEVFEGDVQELAIVPGVQAAYESCEQKE- 225 Query: 242 DDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEE 301 L E G +P+ P P S +++E + Sbjct: 226 --------------------LECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQS 265 Query: 302 QTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGL---------KGQKGEPGVPGPPG 352 Q G + G +V V P G GL G G+PG GPPG Sbjct: 266 QAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPG 325 Query: 353 RAGPPGSPCLPGPPGLPCPV-----SPLGPAGPAL------------QTVPGPQGPPGPP 395 RAG PGS PGPPG + S G GP + Q +GPPGP Sbjct: 326 RAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPM 385 Query: 396 GRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPG 455 G G PG G+PG PG G+ GD GPQG G G GP G G G G G +G PG Sbjct: 386 GYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRG--RAGADGARGMPG 443 Query: 456 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 515 PG + D+ GF G L L G +G G G G+PG PGE G G + Sbjct: 444 DPG--VKGDR---------GFDG-LPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI- 490 Query: 516 PGPAGLPGVPGREG---PPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGS--- 569 GP GLPG G G P G PG+PGPPG G +GP G G G GE G PG +G+ Sbjct: 491 -GPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT 549 Query: 570 KGAPGPAGA---RGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTAR 626 +G PGP GA GE G G PG G PG GPPG PG P G +G GP Sbjct: 550 QGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGP------ 603 Query: 627 SADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPG------------LPGREGIA 674 GP G PG G+KG G+ GL G KGE G DG PGF G +PG G Sbjct: 604 --QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED 661 Query: 675 GPQGPKGDRGSRGEKGDPG----KDGVGQPGLPGPPGPPGPVVYVSEQDGSV--LSVPGP 728 GP+GPKG G G+ G PG K +G PGLPG PG GP GS+ PG Sbjct: 662 GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGP-------KGSLGFPGFPGA 714 Query: 729 EGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDG-------GALG-PAQ 780 G G G G +GP+G G G RG GP+G G+ G+ + G G G P Sbjct: 715 SGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGP 774 Query: 781 KGAKGEPGFRGPPGPYGR------PGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFG 834 +G G PG +GPPGP G+ PG +GE+GF G+ G PG G+ G +G G+ G Sbjct: 775 QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG-PMG 833 Query: 835 MRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPP 894 RG PGPPGPPG G PGT + PGPPG PG GP G +G GE G PG Sbjct: 834 ERGHPGPPGPPGEQGLPGTAGKEGT----KGDPGPPGAPGKDGPAGLRGFPGERGLPGTA 889 Query: 895 GQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIP 953 G +G G G AG GERG G GG G PGP GPPG G G+P Sbjct: 890 GGPGLK------GNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVP 943 Query: 954 GPKG-------ESIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPHRQTISV 1005 G KG + ++G G PGP GPPG+ G +G +G G PG G G H Sbjct: 944 GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEH------ 997 Query: 1006 PGPPGPPGPPGPPGTMGAS 1024 GPPGPPGP GP G GA+ Sbjct: 998 -GPPGPPGPIGPVGQPGAA 1015 Score = 523 bits (1346), Expect = e-148 Identities = 358/865 (41%), Positives = 397/865 (45%), Gaps = 193/865 (22%) Query: 309 GAQTLPGSDSVSTWDGSVRTPG--GRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPP 366 GAQ LPG PG G + G G +G PG GP G GP G P +PGPP Sbjct: 470 GAQGLPGP------------PGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPP 517 Query: 367 GLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPG 426 G+ P GP G GPQG PGPPG+ GTPG G PG G G G+ GPQG PG Sbjct: 518 GVRGMDGPQGPKGSL-----GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPG 572 Query: 427 TPGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS----- 474 PG G G G PG G +GP GPQGP G PGP ++G Sbjct: 573 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 632 Query: 475 -----GFGGDL-----------------EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNS 512 GF GD+ + GP+G GP G PG PGL GE G+ GV Sbjct: 633 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGV-- 690 Query: 513 SDVPGPAGLPGVPGREGP------PGFPG---------LPGPPGPPGREGPPGRTGQKGS 557 GLPG PGR+GP PGFPG L G GP G GP G GQ+G Sbjct: 691 ------PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGP 744 Query: 558 LGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGLPA---- 609 G G G KG+ G GP G GE GL G GP G PGP GPPGPPG PG P Sbjct: 745 RGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGE 804 Query: 610 -GFDDMEGSGGPFWSTA-------------RSADGPQGPPGLPGL---------KGDPGV 646 GF G GP R GP GPPG GL KGDPG Sbjct: 805 VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGP 864 Query: 647 PGLPGAKGEVGADGVPGFPGLPGR------EGIAGPQGPKGDRGSRGEKGDPGKDG-VGQ 699 PG PG G G G PG GLPG +G GP GP G GS GE+G G G +G Sbjct: 865 PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGP 924 Query: 700 PGLPGPPGPPGPVVY--VSEQDGSVLSVPGPEGRPGF---AGFPGPAGP---------KG 745 PG PGP GPPG V + G + GP GR G G PGPAGP KG Sbjct: 925 PGRPGPQGPPGAAGEKGVPGEKGPI----GPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 980 Query: 746 NLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEI 805 +G G++G+ G KGE G PG P G P GA GEPG RGP G +G G +G Sbjct: 981 EVGDPGQKGTKGNKGEHGPPGPP-GPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1039 Query: 806 GFPGRPGRPGMNGL---KGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFA 862 GF G PG G+ GL GEKGE GD G G PGPPGP GP GP G Sbjct: 1040 GFNGPPGPIGLQGLPGPSGEKGETGDV----GPMGPPGPPGPRGPAGPNGA--------- 1086 Query: 863 ESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKG 922 GPPG GN GPPG KG GE G PG +Q E +KG +G+RG+ G+ G Sbjct: 1087 -DGPQGPPGGVGNLGPPGEKGEPGESGSPG---------IQGEPGVKGPRGERGEKGESG 1136 Query: 923 ERGEPGGGGFFG-SSLPGPPGPPGPRGYPGIPGPKGES----------IRGQPGPPGPQG 971 + GEPG G G + GP G PGP G+PG PGP GE RG+ G PG G Sbjct: 1137 QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG 1196 Query: 972 PPGIGYEGRQGPPGPPGPPGPPSFPGPHRQ-----------TISVPG------PPGPPGP 1014 PG G GPPGP G GP PG + I PG P GP G Sbjct: 1197 SPGP--TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1254 Query: 1015 PGPPGTMGASSGV----RLWATRQA 1035 PGP G G V R AT QA Sbjct: 1255 PGPDGLRGLPGSVGQQGRPGATGQA 1279 Score = 432 bits (1112), Expect = e-121 Identities = 306/763 (40%), Positives = 350/763 (45%), Gaps = 146/763 (19%) Query: 309 GAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGL 368 GA G+ S DG PG R GL G +G G PGP G GPPG LPG PG Sbjct: 746 GATGKSGAKGTSGGDGPHGPPGER----GLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQ 801 Query: 369 ------------PCPVSPLGPAGPALQTVP----GPQGPPGPPGRDGTPG---RDGEPGD 409 P P +GP G A +T P G GPPGPPG G PG ++G GD Sbjct: 802 RGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD 861 Query: 410 PGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTF 468 PG G PG GP G G PG+ G G G PG+ G GP GP GP G PG Sbjct: 862 PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG---------- 911 Query: 469 IDMEGSGFGGDLEALRGPRGFPGPPGPPGVPG---LPGEPGRFGVNSSD-------VPGP 518 + +G GG + GP G PGP GPPG G +PGE G G D +PGP Sbjct: 912 -ERGAAGSGGPI----GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGP 966 Query: 519 AGLPGV------------PGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGH 566 AG PGV PG++G G G GPPGPPG GP G+ G G+ GE GA G Sbjct: 967 AGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGP 1026 Query: 567 KGSKGAPGPAGARGESG------LAGAPGPAGPPG------PPGPPGPPGPGLPAGFDDM 614 +G GA G G RG +G L G PGP+G G P GPPGPPGP PAG + Sbjct: 1027 QGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGA 1086 Query: 615 EGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIA 674 +G GP GP G G PG G PG+ G PG KG G G G G PG G Sbjct: 1087 DGPQGPPGGVGNL--GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1144 Query: 675 GPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGF 734 GP+GP GD G KG+PG VG PG PGPPG GP QDG+ G +G PG Sbjct: 1145 GPKGPTGDDGP---KGNPGP--VGFPGDPGPPGEGGP----RGQDGAK-GDRGEDGEPGQ 1194 Query: 735 AGFPGPAG---PKGNLGSKGERGSPGP------KGEKGEPGSIFSPDG----GALGPAQK 781 G PGP G P G LG +G GSPG KG KG+PG+I +P G GPA K Sbjct: 1195 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1254 Query: 782 -------------------GAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGE 822 GA G+ G GP GP G PG +G+ G G G PG+ GL G Sbjct: 1255 PGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGP 1314 Query: 823 KGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPK 882 GE G+ G RG+PGP G PG G G P + GPPGLPG GP G K Sbjct: 1315 PGEQGEK----GDRGLPGPQGSPGQKGEMGIPGASGPI----GPGGPPGLPGPAGPKGAK 1366 Query: 883 GAKGEVGP------------PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGG 930 GA G GP PGPPG+ L ++ K + G + + P GG Sbjct: 1367 GATGPGGPKGEKGVQGPPGHPGPPGEV-IQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGG 1425 Query: 931 GFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPP 973 PG PG G G E I P G Q P Sbjct: 1426 A------PGSPG--GLEEIFGSLDSLREEIEQMRRPTGTQDSP 1460 Score = 380 bits (975), Expect = e-105 Identities = 264/644 (40%), Positives = 293/644 (45%), Gaps = 111/644 (17%) Query: 263 REETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTW 322 R E G K P PP V P A G E E G Q LPG+ Sbjct: 802 RGEVGFQGKTGPPGPPGVVGPQGAAG---ETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 858 Query: 323 DGSVRTPGGRVKEG-----------GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP 371 G PG K+G GL G G PG+ G G +GPPG PG G Sbjct: 859 KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 918 Query: 372 VSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG---PQGFPGTP 428 P+GP G PGPQGPPG G G PG G G G DG G G P G PG Sbjct: 919 GGPIGPPGR-----PGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA 973 Query: 429 GDVGPKGDKGDPGV-------GERGPPGPQGPPGP---PGPSFRHDKLTFIDMEGS-GFG 477 G+ G KG+ GDPG GE GPPGP GP GP PG + + +G G Sbjct: 974 GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK 1033 Query: 478 GDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLP 537 GD G RGF GPPGP G+ GLPG G G + DV GP G PG PG GP G G Sbjct: 1034 GD----EGTRGFNGPPGPIGLQGLPGPSGEKG-ETGDV-GPMGPPGPPGPRGPAGPNGAD 1087 Query: 538 GPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPP 597 GP GPPG G G G+KG GE+G+PG +G G GP G RGE G +G PG GPPGP Sbjct: 1088 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK 1147 Query: 598 GP------------------PGPPGPGLPAGFDDMEGSGG----PFWSTARSADGPQGPP 635 GP PGPPG G P G D +G G P + G GPP Sbjct: 1148 GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPP 1207 Query: 636 GLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKD 695 G G +G G PG G +G GA G PG G PG+ G GP GP G G G +G PG Sbjct: 1208 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1267 Query: 696 GV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERG 754 G G+PG G GPPGPV GP G PG G G G KG+ G G G Sbjct: 1268 GQQGRPGATGQAGPPGPV--------------GPPGLPGLRGDAGAKGEKGHPGLIGLIG 1313 Query: 755 SPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGP---------PGPYGRPGYKGEI 805 PG +GEKG+ G + P G P QKG G PG GP PGP G G KG Sbjct: 1314 PPGEQGEKGDRG-LPGPQGS---PGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGAT 1369 Query: 806 GFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPG 849 G PG P KGEK G+ GPPG PGPPG Sbjct: 1370 G-PGGP--------KGEK-------------GVQGPPGHPGPPG 1391 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 527 bits (1358), Expect = e-149 Identities = 364/889 (40%), Positives = 418/889 (47%), Gaps = 149/889 (16%) Query: 246 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 305 G +G +G+ + + R ETG P PV +P L G T+ + Sbjct: 387 GEAGPTGARGPEGPQGQRGETGP--------PGPVGSPGLPGAIGTDGTP---------- 428 Query: 306 ASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG-----GLKGQKGEPGVPGPPGRAGPPGSP 360 GA+ GS S GS PG +G G++GQ G+PGVPG G AGP G P Sbjct: 429 ---GAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEP 485 Query: 361 CLPGPPGLPCPVSPLGPAGP-ALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT 419 GP G+ P+ P G G + PG GPPGP G G PG G PG DG PG Sbjct: 486 ---GPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGS---DGLPGPK 539 Query: 420 GPQGFPGTPGDVGPKGDKGDPG-VGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS---- 474 G QG G G GPKG +GDPG GE G PG +G G PG KL + G Sbjct: 540 GAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRP 599 Query: 475 ---------GFGGDLEALRGPRGFPGPPGPPG------VPGLPGEPGRFG-VNSSDVPGP 518 G G + L GP+G G PG PG VPG G PG+ G V S GP Sbjct: 600 GPPGSIGIRGQPGSM-GLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGP 658 Query: 519 AGLPGVPGREGPPG---FPGLPGPPGPPGR------EGPPGRTGQKGSLGEAGAPGHKGS 569 GL G G +GPPG F GLPGPPGPPG +G PG G G LG G G+ G Sbjct: 659 PGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGE 718 Query: 570 KGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSAD 629 +G PG G GE G+AG GP GP G PGP G PG P G M G G + D Sbjct: 719 RGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGD 778 Query: 630 -------------------------GPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGF 664 GP GP G G KG+PG GL G G G G G Sbjct: 779 RGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGE 838 Query: 665 PGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG----VGQPGLPGPPGPPGPVVYVSEQDG 720 G G G AGPQGP G G +GE G+PG+ G G GL G PGP GP + G Sbjct: 839 NGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGG 898 Query: 721 -SVLSVPGPEGRPGFAGF---PGPAGPKGNLGSKGERGSPGPKGEKGEPGSIF-----SP 771 PG G PG AG PGPAG G G GE G GP G +G+PGS P Sbjct: 899 RGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGP 958 Query: 772 DGGALGPAQKGAKGE---PGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGD 828 G GP KG GE PG GPPGP G G +G +G PG+ G GM GL G G PG Sbjct: 959 AGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGK 1018 Query: 829 ASL--GFGMRGMPGP------------PGPPGPPGPPGTPVYDSNVFAESSR--PGPPGL 872 G +G PGP PGP GP G GTP D V R PGP GL Sbjct: 1019 VGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGL 1078 Query: 873 PGNQGPPG---PKGAKGEVG---------PPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQ 920 PG+QG PG P GA G+ G P GPPG+ L +G +GD+GD G Sbjct: 1079 PGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLP---GPQGPRGDKGDHGD 1135 Query: 921 KGERGEPGGGGFFG-SSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEG 979 +G+RG+ G GF G LPGPPGP G +G GIPGP G GPPGP GP G Sbjct: 1136 RGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPR-----GPPGPVGP-----SG 1185 Query: 980 RQGPPGPPGPPGPPSFPGPHRQT--ISVPGPPGPPGPPGPPGTMGASSG 1026 ++G PGP GP GPP G + PG PGPPGPPGPPG + A+ G Sbjct: 1186 KEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALG 1234 Score = 514 bits (1323), Expect = e-145 Identities = 337/780 (43%), Positives = 376/780 (48%), Gaps = 143/780 (18%) Query: 331 GRVKEGGLKGQKGEPGVPGPPGRAGP---PGSPCLPGPPGLPCPVSPLG---PAGPALQT 384 GR+ G GQ+G G+PG PG GP PGS PG PG+ P G P GP Q Sbjct: 345 GRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQR 404 Query: 385 ----VPGPQGPPGPPGR---DGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGP---K 434 PGP G PG PG DGTPG G G PG G PG GP G PG G GP + Sbjct: 405 GETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIR 464 Query: 435 GDKGDPGV----------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALR 484 G GDPGV GE GP G QGP GPPG E R Sbjct: 465 GQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGE---------------------EGKR 503 Query: 485 GPRGFPGPPGPPGVPGLPGEPGRFGVNSSD-VPGPAGLPGV---------PGREGPPGFP 534 GPRG PG GPPG G G PG G SD +PGP G G G +G PG P Sbjct: 504 GPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRP 563 Query: 535 GLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPP 594 G PG PG G G PG G +G LG GAPG G G PG G RG+ G G PGP G Sbjct: 564 GEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSS 623 Query: 595 GPPGPPGPPG-PGLPA--GFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPG--- 648 G PG PG G G+P G +G GP GP GPPGL G +G+ G PG Sbjct: 624 GDPGKPGEAGNAGVPGQRGAPGKDGEVGP--------SGPVGPPGLAGERGEQGPPGPTG 675 Query: 649 ---LPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGV-GQPGLPG 704 LPG G G G PG G+PG G GP GP+G+RG+ GE+G+PG G+ G+ G+ G Sbjct: 676 FQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAG 735 Query: 705 PPGPPGPVVYVSEQDGSVLSVPGPEGRPG---------------FAGFPGPAGPKGNLGS 749 GP GP GS PGP G PG AG PGP G +G +G Sbjct: 736 GHGPDGP-------KGS----PGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGE 784 Query: 750 KGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRG---PPGPYGRPGYKGE-- 804 KG G+ G G +G PG + P G GP G KGEPG RG PPG G PG +GE Sbjct: 785 KGAEGTAGNDGARGLPGPLGPP--GPAGPT--GEKGEPGPRGLVGPPGSRGNPGSRGENG 840 Query: 805 ----IGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPG---PPGPPGPPGTPVYD 857 +GF G G G G+KGE GEPG G G PGP G PGP GP G P Sbjct: 841 PTGAVGFAGPQGPDGQPGVKGEPGEPGQK----GDAGSPGPQGLAGSPGPHGPNGVPGLK 896 Query: 858 SNVFAESSRPGPPGLPGNQG---PPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGD 914 + PG G PG+ G PPGP GA G GP G PG+ L+ + G GD Sbjct: 897 GGRGTQGP-PGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGD 955 Query: 915 RGDAGQKGERGEPGGGGFFGSSLPGPPGPPGP------RGYPGIPGPKGESIRGQPGPPG 968 RG AG G G+ G G G PGP GPPGP RG G+PG +GE RG PG PG Sbjct: 956 RGPAGPPGGPGDKGDPGEDGQ--PGPDGPPGPAGTTGQRGIVGMPGQRGE--RGMPGLPG 1011 Query: 969 PQGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGV 1027 P G PG +G G G GPPGP GPP GP G PGP GP G GT G V Sbjct: 1012 PAGTPGKVGPTGATGDKGPPGPVGPPGSNGP-------VGEPGPEGPAGNDGTPGRDGAV 1064 Score = 504 bits (1299), Expect = e-142 Identities = 343/848 (40%), Positives = 390/848 (45%), Gaps = 130/848 (15%) Query: 275 PAPPPVTTPPLA----GGSSTEDSRSEEVEEQT-----TVASLGAQTLPGSDSVSTWDGS 325 P PP P+ GG +T R + ++ V + + P S Sbjct: 85 PVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRG 144 Query: 326 VRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP-------------- 371 R P GR G +G GEPGVPG PG GPPG P PGP GL P Sbjct: 145 ERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGL 204 Query: 372 ----------VSPLGPAGP-ALQTVPGPQGPPGPPGRDGTPGR---------DGEPGDPG 411 V P+GP GP LQ G GP GPPG G PG +G PG PG Sbjct: 205 GSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPG 264 Query: 412 EDGKPG------------DTGPQGFPGTPGDVGPKGDKGDPGV----GERGPPGPQGPPG 455 EDG+PG G +GFPG PG G KG +G G+ GE G PG +G G Sbjct: 265 EDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAG 324 Query: 456 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 515 P GP G G L GPRG PG G G G PG+ G G+ Sbjct: 325 PTGPM--------------GAMGPL----GPRGMPGERGRLGPQGAPGQRGAHGMPGK-- 364 Query: 516 PGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGP 575 PGP G G+PG G PG PG+ G GP G GP G GQ+G G G G G GA G Sbjct: 365 PGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGT 424 Query: 576 AGARGESGLAGAPGPAGPPGPPGPPGPPGP----------GLPA--GFDDMEGSGGPFWS 623 G G G G+PG +GPPG GPPG PGP G P G +G GP Sbjct: 425 DGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGE 484 Query: 624 TA-RSADGPQGPPGLPGL---KGDPGVPGLPGAKGEVGADGVPGFP---GLPGREGIAGP 676 GP GPPG G +GDPG G PG GE GA G GFP GLPG +G G Sbjct: 485 PGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGE 544 Query: 677 QGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAG 736 +GP G G +G +GDPG+ G+PGLPG G G V +G + GP G PG G Sbjct: 545 RGPVGSSGPKGSQGDPGRP--GEPGLPGARGLTGN-PGVQGPEGKL----GPLGAPGEDG 597 Query: 737 FPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPY 796 PGP G G G G G PGPKG G+PG G A P Q+GA G+ G GP GP Sbjct: 598 RPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKP-GEAGNAGVPGQRGAPGKDGEVGPSGPV 656 Query: 797 GRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVY 856 G PG GE G G PG G GL G G PG+ G +G+PG PG GP GP G Sbjct: 657 GPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKP-GDQGVPGDPGAVGPLGPRG---- 711 Query: 857 DSNVFAESSRPGPPGLPGNQ------GPPGPKGAKGEVGPP---GPPGQFPFDFLQLEAE 907 + E PG GLPG + GP GPKG+ G G P GPPG + A Sbjct: 712 ERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAG 771 Query: 908 MKGEKGDRGDAGQKGERGEPGGGGFFGSSLP-GPPGPPGPRGYPGIPGPKG----ESIRG 962 G KGDRG G+KG G G G G P GPPGP GP G G PGP+G RG Sbjct: 772 TPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRG 831 Query: 963 QPGPPGPQGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGP---PGPPGPPGPP 1018 PG G GP G +G+ G QGP G PG G P PG + PGP G PGP GP Sbjct: 832 NPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPG-QKGDAGSPGPQGLAGSPGPHGPN 890 Query: 1019 GTMGASSG 1026 G G G Sbjct: 891 GVPGLKGG 898 Score = 503 bits (1296), Expect = e-142 Identities = 343/845 (40%), Positives = 388/845 (45%), Gaps = 184/845 (21%) Query: 283 PPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQK 342 PP G E R+ E S GA+ PG+ + GLKG + Sbjct: 259 PPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLP----------------GLKGHR 302 Query: 343 GEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPG 402 G G+ GP G G PGS GP G P+ +GP GP + +PG +G GP G G G Sbjct: 303 GHKGLEGPKGEVGAPGSKGEAGPTG---PMGAMGPLGP--RGMPGERGRLGPQGAPGQRG 357 Query: 403 RDGEPGDPGEDGKPGDTGPQGFPGTPG---DVGPKGDKGDPGV----GERGPPGPQGPPG 455 G PG PG G G G GFPG PG + GP G +G G GE GPPGP G PG Sbjct: 358 AHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPG 417 Query: 456 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSD- 514 PG I +G+ +GP G PG GPPG G PG PG G Sbjct: 418 LPGA---------IGTDGT------PGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQG 462 Query: 515 ---VPGPAGLPGVPGREGPPGFPG---LPGPPGPPGREGP------PGRTGQKGSLGEAG 562 PG G+PG G GP G PG + GP GPPG EG PG G G +GE G Sbjct: 463 IRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERG 522 Query: 563 APGHKG---SKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG-PGLPA-----GFDD 613 APG++G S G PGP GA+GE G G+ GP G G PG PG PG PG G Sbjct: 523 APGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQG 582 Query: 614 MEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKG---------EVGADGVPGF 664 EG GP A DG GPPG G++G PG GLPG KG E G GVPG Sbjct: 583 PEGKLGPLG--APGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQ 640 Query: 665 PGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVL 723 G PG++G GP GP G G GE+G+ G G G GLPGPPGPPG + G Sbjct: 641 RGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPG-------EGGK-- 691 Query: 724 SVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSI--FSPDGGALGPAQK 781 PG +G PG G GP GP+G G+ GERG PG G GE G PDG P Sbjct: 692 --PGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSP--- 746 Query: 782 GAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGP 841 G G PG GPPG G PG +G G PG G G G KG +G G+ G RG+PGP Sbjct: 747 GPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGND----GARGLPGP 802 Query: 842 PGPPGPPGPPGTPVYDSNVFAESSRPGPPGL---------PGNQGPPGPKGAKGEVGPPG 892 GPPGP GP G E PGP GL PG++G GP GA G GP G Sbjct: 803 LGPPGPAGPTG----------EKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQG 852 Query: 893 PPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLP-------------- 938 P GQ G KG+ G+ GQKG+ G PG G GS P Sbjct: 853 PDGQ------------PGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRG 900 Query: 939 --GPPG------------PPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI-GYEGRQGP 983 GPPG PPGP G PG GP GE G+ GPPG +G PG G G +GP Sbjct: 901 TQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEP--GKEGPPGLRGDPGSHGRVGDRGP 958 Query: 984 PGPPGPPGPPSFPGPHRQTISVPGPPGPPGP---------------------PGPPGTMG 1022 GPPG PG PG Q PGP GPPGP PG PG G Sbjct: 959 AGPPGGPGDKGDPGEDGQ----PGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAG 1014 Query: 1023 ASSGV 1027 V Sbjct: 1015 TPGKV 1019 Score = 390 bits (1002), Expect = e-108 Identities = 261/638 (40%), Positives = 300/638 (47%), Gaps = 73/638 (11%) Query: 309 GAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGE------------PGVPGPPGRAGP 356 G +PG DG V P G V GL G++GE PG PGPPG G Sbjct: 633 GNAGVPGQRGAPGKDGEVG-PSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGK 691 Query: 357 PGSPCLPGPPGLPCPVSPLGPAG-PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGK 415 PG +PG PG P+ P G G P + PG G PG G G G DG G PG G Sbjct: 692 PGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGT 751 Query: 416 PGDTGPQGFPGTPGD------VGPKGDKGDPGV----------GERGPPGPQGPPGPPGP 459 PGDTGP G G PG+ GPKGD+G G G RG PGP GPPGP GP Sbjct: 752 PGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGP 811 Query: 460 SFRHDK---LTFIDMEGSGFGGDLEALRGPRG---FPGPPGPPGVPGLPGEPGRFGVNS- 512 + + + GS GP G F GP GP G PG+ GEPG G Sbjct: 812 TGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGD 871 Query: 513 SDVPGPAGLPGVPGREGPPGFPGLPG---PPGPPGREGPPGRTGQKGSLGEAGAPGHKGS 569 + PGP GL G PG GP G PGL G GPPG G PG G+ G G AGAPG G Sbjct: 872 AGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGP 931 Query: 570 KGAPG---PAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTAR 626 G PG P G RG+ G G G GP GPPG PG G G +G GP +T + Sbjct: 932 LGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQ 991 Query: 627 SA-------DGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGP 679 G +G PGLPG G PG G GA G+ G G G PG G G GP+GP Sbjct: 992 RGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGP 1051 Query: 680 KGDRGS---------RGEKGDPGKDGV----GQPGLPGPPGPPGPVVYVSEQDGSVLSVP 726 G+ G+ RG++GDPG G+ G PG PGP G PG D Sbjct: 1052 AGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAG--QRGDPGSRGPI 1109 Query: 727 GPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGP-AQKGAKG 785 GP GR G G PGP GP+G+ G G+RG G KG +G G P G GP ++G+ G Sbjct: 1110 GPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLP--GPPGPNGEQGSAG 1167 Query: 786 EPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPP 845 PG GP GP G G G+ G PG G G G++G GE G G G PGPPGPP Sbjct: 1168 IPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPE----GPPGEPGPPGPP 1223 Query: 846 GPPGPPGTPVYDSNVFAESSRPGP-PGLPGNQGPPGPK 882 GPPG + D + S P P P +Q P K Sbjct: 1224 GPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDK 1261 Score = 373 bits (957), Expect = e-103 Identities = 245/586 (41%), Positives = 279/586 (47%), Gaps = 83/586 (14%) Query: 475 GFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFP 534 G G + + G RG PGP GPPG G GE G G PGP G G+ G G PG P Sbjct: 116 GEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGR-----PGPRGPQGIDGEPGVPGQP 170 Query: 535 GLPGPPGPPGREGPPGRT----GQKGSLGEAGAPGHKGS--KGAPGPAGARGESGLAGAP 588 G PGPPG P GP G + Q L E G + G+ GP G RG GL G Sbjct: 171 GAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQ 230 Query: 589 GPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPG 648 G AGP GPPG PG PGP P G + GP+GPPG PG G+PG G Sbjct: 231 GGAGPTGPPGEPGDPGPMGPIG-----------------SRGPEGPPGKPGEDGEPGRNG 273 Query: 649 LPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGP 708 PG G G+ G GFPG PG G+ G +G KG G +GE G PG G + G GP G Sbjct: 274 NPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKG--EAGPTGPMGA 331 Query: 709 PGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSI 768 GP+ GP G PG G GP G G G+ G G PGP G G PGS Sbjct: 332 MGPL--------------GPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSS 377 Query: 769 FSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGD 828 P P KG G G RGP GP G+ +GE G PG G PG+ G G G PG Sbjct: 378 GFPGN----PGMKGEAGPTGARGPEGPQGQ---RGETGPPGPVGSPGLPGAIGTDGTPGA 430 Query: 829 ASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR--PGPPGLPGNQGPPGPKGAKG 886 G G PG GPPG GPPG+P + + R PG PG+PG +G GPKG G Sbjct: 431 K----GPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPG 486 Query: 887 E---VGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSS-LPGPPG 942 GP GPPG+ + + +G+ G G G GERG PG GF GS LPGP G Sbjct: 487 PHGIQGPIGPPGE------EGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKG 540 Query: 943 PPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI----------GYEGRQGP---PGPPGP 989 G RG G GPKG +G PG PG G PG G EG+ GP PG G Sbjct: 541 AQGERGPVGSSGPKGS--QGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGR 598 Query: 990 PGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQA 1035 PGPP G Q S+ G PGP G G PG G + + R A Sbjct: 599 PGPPGSIGIRGQPGSM-GLPGPKGSSGDPGKPGEAGNAGVPGQRGA 643 Score = 71.6 bits (174), Expect = 5e-12 Identities = 47/114 (41%), Positives = 55/114 (48%), Gaps = 14/114 (12%) Query: 927 PGGGGF-FGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPG 985 PGGG FG G G +G PG+ P IRG+PGP GP G G G +GP G Sbjct: 100 PGGGNTNFGR------GRKGQKGEPGLV-PVVTGIRGRPGPAGPPGSQGP--RGERGPKG 150 Query: 986 PPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQ 1039 PGP GP G VPG PG PGPPG P G R ++ + A L + Sbjct: 151 RPGPRGPQGIDGEP----GVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDE 200 >gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo sapiens] Length = 1650 Score = 524 bits (1350), Expect = e-148 Identities = 393/1062 (37%), Positives = 482/1062 (45%), Gaps = 186/1062 (17%) Query: 66 LAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIR--PATEGPGVLFAITDSAQAMVLLGV 123 +AY A R FP F +DFSLL +R P + P + SAQ + LG+ Sbjct: 58 VAYRVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLY---SAQGVRQLGL 114 Query: 124 KLSGVQDGHQDISLLYTEP-GAGQTHTAASFR-LPAFVGQWTHLALSVAGGFVALYVDCE 181 +L + + LY + G Q + FR L G+W +A++V G V L VDC+ Sbjct: 115 ELG------RPVRFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCK 168 Query: 182 EFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEG 241 + PL RS+R + G +F A+ D + F+G + EL + Q + C +E Sbjct: 169 KRVTRPLPRSARPVLDTHGVIIFGARI--LDEEVFEGDVQELAIVPGVQAAYESCEQKE- 225 Query: 242 DDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEE 301 L E G +P+ P P S +++E + Sbjct: 226 --------------------LECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQS 265 Query: 302 QTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGV-------PGPPG 352 Q PG + + S+ P G GLKG+KGEP V GPPG Sbjct: 266 QDPT--------PGEEE-EILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPG 316 Query: 353 RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQT-VPGPQGPPGPPG-------RDGTPGRD 404 GP G PG G P PV G GP + +PG G PGPPG R G+ G D Sbjct: 317 PEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGD 376 Query: 405 GEP---------------------GDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVG 443 P G PG G G GP G PG+PG G GD +G Sbjct: 377 KGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGD-----LG 431 Query: 444 ERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS-GFGGDLEALRGPRGFPGPPGPPG----- 497 +GP GPQG GPPG + R + +G+ G GD ++G RGF G PG PG Sbjct: 432 PQGPRGPQGLTGPPGKAGRRGRA---GADGARGMPGD-PGVKGDRGFDGLPGLPGEKGHR 487 Query: 498 ----VPGLPGEPGRFGVNSSDVP-GPAGLPGVPGREG---PPGFPGLPGPPGPPGREGPP 549 GLPG PG G D GP GLPG G G P G PG+PGPPG G +GP Sbjct: 488 GDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQ 547 Query: 550 GRTGQKGSLGEAGAPGHKGS---KGAPGPAGA---RGESGLAGAPGPAGPPGPPGPPGPP 603 G G G GE G PG +G+ +G PGP GA GE G G PG G PG GPPG P Sbjct: 548 GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP 607 Query: 604 GPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPG 663 G P G +G GP GP G PG G+KG G+ GL G KGE G DG PG Sbjct: 608 GKEGPPGTKGNQGPSGP--------QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPG 659 Query: 664 FPG------------LPGREGIAGPQGPKGDRGSRGEKGDPG----KDGVGQPGLPGPPG 707 F G +PG G GP+GPKG G G+ G PG K +G PGLPG PG Sbjct: 660 FKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPG 719 Query: 708 PPGPVVYVSEQDGSV--LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEP 765 GP GS+ PG G G G G +GP+G G G RG GP+G G+ Sbjct: 720 RQGP-------KGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKS 772 Query: 766 GSIFSPDG-------GALG-PAQKGAKGEPGFRGPPGPYGR------PGYKGEIGFPGRP 811 G+ + G G G P +G G PG +GPPGP G+ PG +GE+GF G+ Sbjct: 773 GAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKT 832 Query: 812 GRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPG 871 G PG G+ G +G G+ G RG PGPPGPPG G PGT + PGPPG Sbjct: 833 GPPGPPGVVGPQGAAGETG-PMGERGHPGPPGPPGEQGLPGTAGKEGT----KGDPGPPG 887 Query: 872 LPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGG 931 PG GP G +G GE G PG G +G G G AG GERG G GG Sbjct: 888 APGKDGPAGLRGFPGERGLPGTAGGPGLK------GNEGPSGPPGPAGSPGERGAAGSGG 941 Query: 932 FFGS-SLPGPPGPPGPRGYPGIPGPKG-------ESIRGQPGPPGPQGPPGI-GYEGRQG 982 G PGP GPPG G G+PG KG + ++G G PGP GPPG+ G +G +G Sbjct: 942 PIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 1001 Query: 983 PPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGAS 1024 G PG G G H GPPGPPGP GP G GA+ Sbjct: 1002 EVGDPGQKGTKGNKGEH-------GPPGPPGPIGPVGQPGAA 1036 Score = 523 bits (1346), Expect = e-148 Identities = 358/865 (41%), Positives = 397/865 (45%), Gaps = 193/865 (22%) Query: 309 GAQTLPGSDSVSTWDGSVRTPG--GRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPP 366 GAQ LPG PG G + G G +G PG GP G GP G P +PGPP Sbjct: 491 GAQGLPGP------------PGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPP 538 Query: 367 GLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPG 426 G+ P GP G GPQG PGPPG+ GTPG G PG G G G+ GPQG PG Sbjct: 539 GVRGMDGPQGPKGSL-----GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPG 593 Query: 427 TPGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS----- 474 PG G G G PG G +GP GPQGP G PGP ++G Sbjct: 594 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 653 Query: 475 -----GFGGDL-----------------EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNS 512 GF GD+ + GP+G GP G PG PGL GE G+ GV Sbjct: 654 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGV-- 711 Query: 513 SDVPGPAGLPGVPGREGP------PGFPG---------LPGPPGPPGREGPPGRTGQKGS 557 GLPG PGR+GP PGFPG L G GP G GP G GQ+G Sbjct: 712 ------PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGP 765 Query: 558 LGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGLPA---- 609 G G G KG+ G GP G GE GL G GP G PGP GPPGPPG PG P Sbjct: 766 RGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGE 825 Query: 610 -GFDDMEGSGGPFWSTA-------------RSADGPQGPPGLPGL---------KGDPGV 646 GF G GP R GP GPPG GL KGDPG Sbjct: 826 VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGP 885 Query: 647 PGLPGAKGEVGADGVPGFPGLPGR------EGIAGPQGPKGDRGSRGEKGDPGKDG-VGQ 699 PG PG G G G PG GLPG +G GP GP G GS GE+G G G +G Sbjct: 886 PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGP 945 Query: 700 PGLPGPPGPPGPVVY--VSEQDGSVLSVPGPEGRPGF---AGFPGPAGP---------KG 745 PG PGP GPPG V + G + GP GR G G PGPAGP KG Sbjct: 946 PGRPGPQGPPGAAGEKGVPGEKGPI----GPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 1001 Query: 746 NLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEI 805 +G G++G+ G KGE G PG P G P GA GEPG RGP G +G G +G Sbjct: 1002 EVGDPGQKGTKGNKGEHGPPGPP-GPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1060 Query: 806 GFPGRPGRPGMNGL---KGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFA 862 GF G PG G+ GL GEKGE GD G G PGPPGP GP GP G Sbjct: 1061 GFNGPPGPIGLQGLPGPSGEKGETGDV----GPMGPPGPPGPRGPAGPNGA--------- 1107 Query: 863 ESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKG 922 GPPG GN GPPG KG GE G PG +Q E +KG +G+RG+ G+ G Sbjct: 1108 -DGPQGPPGGVGNLGPPGEKGEPGESGSPG---------IQGEPGVKGPRGERGEKGESG 1157 Query: 923 ERGEPGGGGFFG-SSLPGPPGPPGPRGYPGIPGPKGES----------IRGQPGPPGPQG 971 + GEPG G G + GP G PGP G+PG PGP GE RG+ G PG G Sbjct: 1158 QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG 1217 Query: 972 PPGIGYEGRQGPPGPPGPPGPPSFPGPHRQ-----------TISVPG------PPGPPGP 1014 PG G GPPGP G GP PG + I PG P GP G Sbjct: 1218 SPGP--TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1275 Query: 1015 PGPPGTMGASSGV----RLWATRQA 1035 PGP G G V R AT QA Sbjct: 1276 PGPDGLRGLPGSVGQQGRPGATGQA 1300 Score = 432 bits (1112), Expect = e-121 Identities = 306/763 (40%), Positives = 350/763 (45%), Gaps = 146/763 (19%) Query: 309 GAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGL 368 GA G+ S DG PG R GL G +G G PGP G GPPG LPG PG Sbjct: 767 GATGKSGAKGTSGGDGPHGPPGER----GLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQ 822 Query: 369 ------------PCPVSPLGPAGPALQTVP----GPQGPPGPPGRDGTPG---RDGEPGD 409 P P +GP G A +T P G GPPGPPG G PG ++G GD Sbjct: 823 RGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD 882 Query: 410 PGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTF 468 PG G PG GP G G PG+ G G G PG+ G GP GP GP G PG Sbjct: 883 PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG---------- 932 Query: 469 IDMEGSGFGGDLEALRGPRGFPGPPGPPGVPG---LPGEPGRFGVNSSD-------VPGP 518 + +G GG + GP G PGP GPPG G +PGE G G D +PGP Sbjct: 933 -ERGAAGSGGPI----GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGP 987 Query: 519 AGLPGV------------PGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGH 566 AG PGV PG++G G G GPPGPPG GP G+ G G+ GE GA G Sbjct: 988 AGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGP 1047 Query: 567 KGSKGAPGPAGARGESG------LAGAPGPAGPPG------PPGPPGPPGPGLPAGFDDM 614 +G GA G G RG +G L G PGP+G G P GPPGPPGP PAG + Sbjct: 1048 QGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGA 1107 Query: 615 EGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIA 674 +G GP GP G G PG G PG+ G PG KG G G G G PG G Sbjct: 1108 DGPQGPPGGVGNL--GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1165 Query: 675 GPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGF 734 GP+GP GD G KG+PG VG PG PGPPG GP QDG+ G +G PG Sbjct: 1166 GPKGPTGDDGP---KGNPGP--VGFPGDPGPPGEGGP----RGQDGAK-GDRGEDGEPGQ 1215 Query: 735 AGFPGPAG---PKGNLGSKGERGSPGP------KGEKGEPGSIFSPDG----GALGPAQK 781 G PGP G P G LG +G GSPG KG KG+PG+I +P G GPA K Sbjct: 1216 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1275 Query: 782 -------------------GAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGE 822 GA G+ G GP GP G PG +G+ G G G PG+ GL G Sbjct: 1276 PGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGP 1335 Query: 823 KGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPK 882 GE G+ G RG+PGP G PG G G P + GPPGLPG GP G K Sbjct: 1336 PGEQGEK----GDRGLPGPQGSPGQKGEMGIPGASGPI----GPGGPPGLPGPAGPKGAK 1387 Query: 883 GAKGEVGP------------PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGG 930 GA G GP PGPPG+ L ++ K + G + + P GG Sbjct: 1388 GATGPGGPKGEKGVQGPPGHPGPPGEV-IQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGG 1446 Query: 931 GFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPP 973 PG PG G G E I P G Q P Sbjct: 1447 A------PGSPG--GLEEIFGSLDSLREEIEQMRRPTGTQDSP 1481 Score = 380 bits (975), Expect = e-105 Identities = 264/644 (40%), Positives = 293/644 (45%), Gaps = 111/644 (17%) Query: 263 REETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTW 322 R E G K P PP V P A G E E G Q LPG+ Sbjct: 823 RGEVGFQGKTGPPGPPGVVGPQGAAG---ETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 879 Query: 323 DGSVRTPGGRVKEG-----------GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP 371 G PG K+G GL G G PG+ G G +GPPG PG G Sbjct: 880 KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 939 Query: 372 VSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG---PQGFPGTP 428 P+GP G PGPQGPPG G G PG G G G DG G G P G PG Sbjct: 940 GGPIGPPGR-----PGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA 994 Query: 429 GDVGPKGDKGDPGV-------GERGPPGPQGPPGP---PGPSFRHDKLTFIDMEGS-GFG 477 G+ G KG+ GDPG GE GPPGP GP GP PG + + +G G Sbjct: 995 GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK 1054 Query: 478 GDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLP 537 GD G RGF GPPGP G+ GLPG G G + DV GP G PG PG GP G G Sbjct: 1055 GD----EGTRGFNGPPGPIGLQGLPGPSGEKG-ETGDV-GPMGPPGPPGPRGPAGPNGAD 1108 Query: 538 GPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPP 597 GP GPPG G G G+KG GE+G+PG +G G GP G RGE G +G PG GPPGP Sbjct: 1109 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK 1168 Query: 598 GP------------------PGPPGPGLPAGFDDMEGSGG----PFWSTARSADGPQGPP 635 GP PGPPG G P G D +G G P + G GPP Sbjct: 1169 GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPP 1228 Query: 636 GLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKD 695 G G +G G PG G +G GA G PG G PG+ G GP GP G G G +G PG Sbjct: 1229 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1288 Query: 696 GV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERG 754 G G+PG G GPPGPV GP G PG G G G KG+ G G G Sbjct: 1289 GQQGRPGATGQAGPPGPV--------------GPPGLPGLRGDAGAKGEKGHPGLIGLIG 1334 Query: 755 SPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGP---------PGPYGRPGYKGEI 805 PG +GEKG+ G + P G P QKG G PG GP PGP G G KG Sbjct: 1335 PPGEQGEKGDRG-LPGPQGS---PGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGAT 1390 Query: 806 GFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPG 849 G PG P KGEK G+ GPPG PGPPG Sbjct: 1391 G-PGGP--------KGEK-------------GVQGPPGHPGPPG 1412 >gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] Length = 1669 Score = 523 bits (1347), Expect = e-148 Identities = 358/878 (40%), Positives = 414/878 (47%), Gaps = 159/878 (18%) Query: 324 GSVRTPGGRVKEGGLKGQKGEPG----VPGPPGRAGPPGSPCLPGP------------PG 367 G PGG G L G KGEPG +PGPPG G PGSP PGP PG Sbjct: 618 GQAGFPGGPGSPG-LPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPG 676 Query: 368 LPCPVSPLG--------PAGP-ALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGD 418 LP +G P GP + +PG GPPG PGR G G G PG G+ G+PG Sbjct: 677 LPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGV 736 Query: 419 -----TGPQGFPGTPGDVGPKGDKGDPGV----GERGPPGPQGPPGPPGPSFRHDKLTFI 469 G G PG PG G KG G PGV G GPPG QG G PGP + Sbjct: 737 GLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSP 796 Query: 470 DMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGP----------- 518 + G G G RGP G GPPG G PG+ GE G G D+PGP Sbjct: 797 GVPGIGPPG----ARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPG 852 Query: 519 ----AGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPG 574 +GLPG+PG++G PG PG PG G G G PG+ G G +G G PG KG G PG Sbjct: 853 ITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPG 912 Query: 575 PAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGS-------------GGPF 621 +G RG+ GL G G G PG PG G G +G G P Sbjct: 913 SSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPG 972 Query: 622 WSTARSADGPQGPPGLPGLKGDPGV------PGLPGAKGEVGADGVPGFPGLPGREGIAG 675 DG G PG PG KGDPG+ PGLPG KG VG G+PG PG G GI G Sbjct: 973 TPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPG 1032 Query: 676 PQGP---KGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSE-----QDGSVLSVPG 727 PQG GD+G++GEKG G G+G PGL G G G + + GS+ +PG Sbjct: 1033 PQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSI-GIPG 1091 Query: 728 PEGRPGFAGFPGPAGPKGNLGSKGERGS---------PGPKGEKGEPGSIFSPDG--GAL 776 G PG G PG G G+ G GE+G PG KGE G PG+ P G G Sbjct: 1092 MPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTP-GPTGPAGQK 1150 Query: 777 G-------PAQKGAKGEP-----GFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEK- 823 G P G KGEP GF G PG G G KGE+GFPG G PG+ G KGE+ Sbjct: 1151 GEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQG 1210 Query: 824 --------------GEPGDASLG----FGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESS 865 G PG A+ G G +G PG PG PGP GPPG P D V + Sbjct: 1211 FMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGID-GVKGDKG 1269 Query: 866 RPGPPGLPGNQGP---------------PGPKGAKGEVGPPGPPG-QFPFDFLQLEAEMK 909 PG PG PG GP PG G+KG++GPPG PG Q P L+ +K Sbjct: 1270 NPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQG-IK 1328 Query: 910 GEKGDRGDAGQKGERGEPGGGGFFG-----SSLPGPPGPPGPRGYPGIPGPKG-ESIRGQ 963 G++GD+G G KG G PG G + LPGP GPPG +G G+PGPKG + + G Sbjct: 1329 GDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGL 1388 Query: 964 PGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1022 G PGP G PG G G++G GP GP GP FPGP PGP G PG GPPGT Sbjct: 1389 VGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGP-------PGPDGLPGSMGPPGTPS 1441 Query: 1023 ASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVR 1060 G TR + + P G I LYV+ Sbjct: 1442 VDHG--FLVTRHSQTIDDPQCPSGTKILYHGYSLLYVQ 1477 Score = 491 bits (1264), Expect = e-138 Identities = 340/851 (39%), Positives = 385/851 (45%), Gaps = 177/851 (20%) Query: 309 GAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGS---PCLPGP 365 G + LPG V + G ++ P G G KG GEPG+PG G GPPG+ P PG Sbjct: 49 GERGLPGLQGVIGFPG-MQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGL 107 Query: 366 PGLPCPVSPLGPAG-PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT----- 419 PG+P P GP G P G +GP GPPG G G G PG PG G PG+ Sbjct: 108 PGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVP 167 Query: 420 -----GPQGFPGTPGDVGPKGDKGDPGV----GERGPPGPQGPPGPPGPSFRHDKLTFID 470 G +GFPG PG GP G G G G GPPGP GPPGPPG Sbjct: 168 GMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPG------------ 215 Query: 471 MEGSGFGGDLEALRGPRGFPGPPGPPGVPGL--------------------PGEPGRFGV 510 E G + +G +G G GPPGVPG PG G GV Sbjct: 216 -EKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGV 274 Query: 511 NSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSK 570 PG G G PG++G G G PG PG PG G GR G +G GEAG PG G Sbjct: 275 GEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIV 334 Query: 571 GAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGLPA-------GFDDMEGSGG 619 GP G +GE G G PGP G PGP G PG PG PGLP GF G G Sbjct: 335 IGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKG 394 Query: 620 PFWSTARSADGPQGPPGLPGLKGDPGVPGLPG--------AKGEVGADGVPGFPGLPGRE 671 S GP G GLPG G PG PG PG G G G PG PG PG Sbjct: 395 DRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFI 454 Query: 672 GIAGPQGPKGD----------RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDG 720 G G +G KG+ RG G +G PG+ G GQPG G G PG +DG Sbjct: 455 GEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPG-------RDG 507 Query: 721 SVLSVPGPEGRPGF-------------------------AGFPGPAGPKGNLGSKGERGS 755 V VPGP+G PG GFPG G G GS G G Sbjct: 508 -VAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGH 566 Query: 756 PGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGY--------KGEIGF 807 PG G KG PGS+ G GP G G PG RG GP G PGY KG+ GF Sbjct: 567 PGLPGPKGSPGSVGLK--GERGP--PGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGF 622 Query: 808 PGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRP 867 PG PG PG+ G KGE G+ G G+PG PG PGP G G P P Sbjct: 623 PGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFP----------GTP 672 Query: 868 GPPGLPGNQ-----------GPPGPKGA---KGEVGPPGPPGQFPFDFLQLEAEMKGEKG 913 G PGLPG + GPPGPKG G++GPPG PG+ F+ L ++G+KG Sbjct: 673 GRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKG 732 Query: 914 DRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKG-------ESIRGQPGP 966 + G G G +G PG G +PG PG G G PG+PG G + IRG+PGP Sbjct: 733 EPG-VGLPGLKGLPGLPG-----IPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGP 786 Query: 967 P------GPQGPPGIGYEGRQGPPGPPGPP---GPPSFPG----PHRQTISVPGPPGPPG 1013 P G G PGIG G +GPPG GPP GPP G P + +PGP G G Sbjct: 787 PGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKG 846 Query: 1014 PPGPPGTMGAS 1024 G PG G S Sbjct: 847 AQGLPGITGQS 857 Score = 446 bits (1148), Expect = e-125 Identities = 313/767 (40%), Positives = 353/767 (46%), Gaps = 160/767 (20%) Query: 385 VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDV---GPKGDKGDPG 441 V G +G G PG G G G G G G PG G G PG PG GP G G PG Sbjct: 44 VKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPG 103 Query: 442 -VGERGPPGPQGPPGPPG-PSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVP 499 G G PG GPPGPPG P K G G L G GF G PGPPG+P Sbjct: 104 NPGLPGIPGQDGPPGPPGIPGCNGTK---------GERGPL-GPPGLPGFAGNPGPPGLP 153 Query: 500 GLPGEPGRF--GVNSSDVPGPAGLPGVPGREGPPGFPGL---------PGPPGPPGREGP 548 G+ G+PG V + G G PG+PG GPPG PGL GPPGPPG GP Sbjct: 154 GMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGP 213 Query: 549 PGRTGQ-----------KGSLGEAGAPG--------HKGSKGAPGPAGARGESGLAGAP- 588 PG GQ KG G +G PG KG G G +GE G G P Sbjct: 214 PGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPG 273 Query: 589 -GPAGPPGPPGPPGPPG----------PGLPA--GFDDMEGSGGPFWSTARSADGPQGPP 635 G G PG PGP G PG PG P G+ + G GP + GP GPP Sbjct: 274 VGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGP--QGEKGEAGPPGPP 331 Query: 636 GLP------GLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREG--IAGPQGPKGDRGSRG 687 G+ G KG+ G PG PG +GE G G PG PG PG G + G G G G RG Sbjct: 332 GIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERG 391 Query: 688 EKGDPGKDGV------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGP---------EGRP 732 EKGD G G G+ GLPGPPG PGP +G V PGP G+P Sbjct: 392 EKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQP 451 Query: 733 GFAGF----------------------PGPAGPKGNL------GSKGERGSPGPKGEKGE 764 GF G PGP GP G + G+KG+RG PG G G Sbjct: 452 GFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGV 511 Query: 765 PGSIFSP----DGGALG-PAQ-------KGAKGEPGFRGPPGPYGR---PGYKGEIGFPG 809 PG +P GA G P + KG KG+PGF G PG GR PG G G PG Sbjct: 512 PGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPG 571 Query: 810 RPGRPGMNGLKGEKGEPGDASLGF-GMRGMPGPPGPP--GPPGPPGTPVYDSNVFAESSR 866 G PG GLKGE+G PG +GF G RG GPPGPP GP GP G + + Sbjct: 572 PKGSPGSVGLKGERGPPG--GVGFPGSRGDTGPPGPPGYGPAGPIG----------DKGQ 619 Query: 867 PGPPGLPGNQGPPGPKGAKGEVGP-PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERG 925 G PG PG+ G PGPKG G++ P PGPPG + L G +GDRG G G G Sbjct: 620 AGFPGGPGSPGLPGPKGEPGKIVPLPGPPGA---EGLPGSPGFPGPQGDRGFPGTPGRPG 676 Query: 926 EPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKG----------ESIRGQPGPPGPQGPPGI 975 PG G G G PGPPGP+G G+PG G + G PG G +G PG+ Sbjct: 677 LPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGV 736 Query: 976 GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1022 G G +G PG PG PG P G +I VPG PG G GPPG G Sbjct: 737 GLPGLKGLPGLPGIPGTPGEKG----SIGVPGVPGEHGAIGPPGLQG 779 Score = 324 bits (830), Expect = 4e-88 Identities = 232/590 (39%), Positives = 259/590 (43%), Gaps = 156/590 (26%) Query: 559 GEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG-PGLPAGFDDMEGS 617 G+ G KG KG G G +G G G GP GP GPPG G G PGLP +G+ Sbjct: 37 GKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPG----TKGT 92 Query: 618 GGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQ 677 GP A G G PG+PG G PG PG+PG G G G G PGLPG G GP Sbjct: 93 RGP--PGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPP 150 Query: 678 GPKGDRGSRGE----------KGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPG 727 G G +G GE KG+ G G+ PG PGPPG PG + G Sbjct: 151 GLPGMKGDPGEILGHVPGMLLKGERGFPGI--PGTPGPPGLPG--------------LQG 194 Query: 728 PEGRPGFAGFPGPAGPKGNLGSKGERGSP--GPKGEKGEPGSIFSPDGGALGPAQ----- 780 P G PGF G PGP GP G G KG+ G GPKG+KG+ G P G G AQ Sbjct: 195 PVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPP--GVPGQAQVQEKG 252 Query: 781 -------KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPG-DASLG 832 KG KGEPGF+G PG G KGE G PG G+PG +G KGEKG PG G Sbjct: 253 DFATKGEKGQKGEPGFQGMPGV----GEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPG 308 Query: 833 F-GMRGMPGPPGPPGPPGPPGTP--VYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVG 889 + G+ G GP G G GPPG P V + E G PG PG +G PGPKG G G Sbjct: 309 YPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPG 368 Query: 890 PPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGP------PGP 943 PGPPG P G G G GERGE G GF G+SLPGP PGP Sbjct: 369 QPGPPG-LPVP------------GQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGP 415 Query: 944 PGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI-----------------------GYEGR 980 PG G PG PG + QPGPPG QGPPGI +G Sbjct: 416 PGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGY 475 Query: 981 QGPPGPPGPPGPPSFPG----------PHRQTIS-VPGPPGPPG---------------- 1013 +GPPGP GPPG FPG P R ++ VPGP G PG Sbjct: 476 RGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYF 535 Query: 1014 ------------------------------PPGPPGTMGASSGVRLWATR 1033 PG PG G+ V L R Sbjct: 536 DLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGER 585 Score = 298 bits (762), Expect = 3e-80 Identities = 194/479 (40%), Positives = 222/479 (46%), Gaps = 87/479 (18%) Query: 244 SDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRS--EEVEE 301 S G GD G+ + E G A PP + P L G + E Sbjct: 1036 SPGLPGDKGA---------KGEKGQA------GPPGIGIPGLRGEKGDQGIAGFPGSPGE 1080 Query: 302 QTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPC 361 + S+G +PGS + GSV PG GL G+KG+ G+PG G G G Sbjct: 1081 KGEKGSIGIPGMPGSPGLKGSPGSVGYPG----SPGLPGEKGDKGLPGLDGIPGVKGEAG 1136 Query: 362 LPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGE--PGDPGEDGKPGDT 419 LPG PG P GPAG + PG G PG G G PG G PG PG G G Sbjct: 1137 LPGTPG------PTGPAGQ--KGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSK 1188 Query: 420 GPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGD 479 G GFPG G G G KG+ G GPPGPQG PG P G Sbjct: 1189 GEVGFPGLAGSPGIPGSKGEQGF--MGPPGPQGQPGLP-------------------GSP 1227 Query: 480 LEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGP 539 A GP+G GP G PG+PGLPG G PG G+ GV G +G PG+PG PG Sbjct: 1228 GHATEGPKGDRGPQGQPGLPGLPGPMG--------PPGLPGIDGVKGDKGNPGWPGAPGV 1279 Query: 540 PGP---------PGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGP 590 PGP PG G PG TG KG +G G PG +G KG PG G +G+ G G PG Sbjct: 1280 PGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGA 1339 Query: 591 AGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLP 650 G PGPPGPPGP +D ++G G GP+GPPGL GL+G PG G Sbjct: 1340 KGLPGPPGPPGP--------YDIIKGEPG--------LPGPEGPPGLKGLQGLPGPKGQQ 1383 Query: 651 GAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPP 709 G G VG G PG PG G G G GP G G RG G PG DG+ PG GPPG P Sbjct: 1384 GVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGL--PGSMGPPGTP 1440 Score = 76.3 bits (186), Expect = 2e-13 Identities = 61/199 (30%), Positives = 73/199 (36%), Gaps = 47/199 (23%) Query: 245 DGASGDSGSGLGDARELLREETGAALKPRLPAP---PPVTTPPLAGGSSTEDSRSEEVEE 301 DG GD G+ G P +P P P P GGS ++ Sbjct: 1262 DGVKGDKGN------------PGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGP 1309 Query: 302 QTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGG---------LKGQKGEPGVPGPPG 352 G + LPG + G PG + G +KG+ G PG GPPG Sbjct: 1310 PGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPG 1369 Query: 353 R------------------AGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGP 394 G PG P +PG G P +GPAGP GP+G PGP Sbjct: 1370 LKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPT-----GPRGFPGP 1424 Query: 395 PGRDGTPGRDGEPGDPGED 413 PG DG PG G PG P D Sbjct: 1425 PGPDGLPGSMGPPGTPSVD 1443 >gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo sapiens] Length = 1736 Score = 523 bits (1346), Expect = e-148 Identities = 358/865 (41%), Positives = 397/865 (45%), Gaps = 193/865 (22%) Query: 309 GAQTLPGSDSVSTWDGSVRTPG--GRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPP 366 GAQ LPG PG G + G G +G PG GP G GP G P +PGPP Sbjct: 577 GAQGLPGP------------PGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPP 624 Query: 367 GLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPG 426 G+ P GP G GPQG PGPPG+ GTPG G PG G G G+ GPQG PG Sbjct: 625 GVRGMDGPQGPKGSL-----GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPG 679 Query: 427 TPGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS----- 474 PG G G G PG G +GP GPQGP G PGP ++G Sbjct: 680 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 739 Query: 475 -----GFGGDL-----------------EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNS 512 GF GD+ + GP+G GP G PG PGL GE G+ GV Sbjct: 740 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGV-- 797 Query: 513 SDVPGPAGLPGVPGREGP------PGFPG---------LPGPPGPPGREGPPGRTGQKGS 557 GLPG PGR+GP PGFPG L G GP G GP G GQ+G Sbjct: 798 ------PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGP 851 Query: 558 LGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGLPA---- 609 G G G KG+ G GP G GE GL G GP G PGP GPPGPPG PG P Sbjct: 852 RGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGE 911 Query: 610 -GFDDMEGSGGPFWSTA-------------RSADGPQGPPGLPGL---------KGDPGV 646 GF G GP R GP GPPG GL KGDPG Sbjct: 912 VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGP 971 Query: 647 PGLPGAKGEVGADGVPGFPGLPGR------EGIAGPQGPKGDRGSRGEKGDPGKDG-VGQ 699 PG PG G G G PG GLPG +G GP GP G GS GE+G G G +G Sbjct: 972 PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGP 1031 Query: 700 PGLPGPPGPPGPVVY--VSEQDGSVLSVPGPEGRPGF---AGFPGPAGP---------KG 745 PG PGP GPPG V + G + GP GR G G PGPAGP KG Sbjct: 1032 PGRPGPQGPPGAAGEKGVPGEKGPI----GPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 1087 Query: 746 NLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEI 805 +G G++G+ G KGE G PG P G P GA GEPG RGP G +G G +G Sbjct: 1088 EVGDPGQKGTKGNKGEHGPPGPP-GPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1146 Query: 806 GFPGRPGRPGMNGL---KGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFA 862 GF G PG G+ GL GEKGE GD G G PGPPGP GP GP G Sbjct: 1147 GFNGPPGPIGLQGLPGPSGEKGETGDV----GPMGPPGPPGPRGPAGPNGA--------- 1193 Query: 863 ESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKG 922 GPPG GN GPPG KG GE G PG +Q E +KG +G+RG+ G+ G Sbjct: 1194 -DGPQGPPGGVGNLGPPGEKGEPGESGSPG---------IQGEPGVKGPRGERGEKGESG 1243 Query: 923 ERGEPGGGGFFG-SSLPGPPGPPGPRGYPGIPGPKGES----------IRGQPGPPGPQG 971 + GEPG G G + GP G PGP G+PG PGP GE RG+ G PG G Sbjct: 1244 QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG 1303 Query: 972 PPGIGYEGRQGPPGPPGPPGPPSFPGPHRQ-----------TISVPG------PPGPPGP 1014 PG G GPPGP G GP PG + I PG P GP G Sbjct: 1304 SPGP--TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1361 Query: 1015 PGPPGTMGASSGV----RLWATRQA 1035 PGP G G V R AT QA Sbjct: 1362 PGPDGLRGLPGSVGQQGRPGATGQA 1386 Score = 497 bits (1280), Expect = e-140 Identities = 393/1112 (35%), Positives = 481/1112 (43%), Gaps = 199/1112 (17%) Query: 66 LAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIR--PATEGPGVLFAITDSAQAMVLLGV 123 +AY A R FP F +DFSLL +R P + P + SAQ + LG+ Sbjct: 58 VAYRVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLY---SAQGVRQLGL 114 Query: 124 KLSGVQDGHQDISLLYTEP-GAGQTHTAASFR-LPAFVGQWTHLALSVAGGFVALYVDCE 181 +L + + LY + G Q + FR L G+W +A++V G V L VDC+ Sbjct: 115 ELG------RPVRFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCK 168 Query: 182 EFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEG 241 + PL RS+R + G +F A+ D + F+G + EL + Q + C +E Sbjct: 169 KRVTRPLPRSARPVLDTHGVIIFGARI--LDEEVFEGDVQELAIVPGVQAAYESCEQKEL 226 Query: 242 DDSDG-ASGDSGSGLGDARELLREETGAALKPRLPAP-------------PP----VTTP 283 + G A+ +++ +P+ P PP +TT Sbjct: 227 ECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQPTESLYYDYEPPYYDVMTTG 286 Query: 284 PLAGGSSTEDSRSEEVEEQTTVASL-----GAQTLPGSDSVST---WDGSVRTPGGRVK- 334 EE+ E + + L Q P +D +G P G Sbjct: 287 TTPDYQDPTPGEEEEILESSLLPPLEEEQTDLQVPPTADRFQAEEYGEGGTDPPEGPYDY 346 Query: 335 EGGLKGQKGEPGVPGPP-------GRAGPPGSPCLPGPPGLPC----------PVSPLGP 377 G E GP A G L G G P P P GP Sbjct: 347 TYGYGDDYREETELGPALSAETAHSGAAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGP 406 Query: 378 AG----PALQTVPGPQGPP---GPPGRDGTPGRDGEPGDPGED----------------- 413 AG P +Q PGP G P GPPGR G PG DG PG PG Sbjct: 407 AGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPV 466 Query: 414 --------------------GKPGDTGPQGFPGTPGDVGPKGDKGDPG-VGERGPPGPQG 452 G PG G G PG G G G KG+ G +G +GP GPQG Sbjct: 467 VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 526 Query: 453 PPGPPGPSFRHDKLTFIDMEGS-GFGGDLEALRGPRGFPGPPGPP---------GVPGLP 502 GPPG + R + +G+ G GD ++G RGF G PG P G GLP Sbjct: 527 LTGPPGKAGRRGR---AGADGARGMPGD-PGVKGDRGFDGLPGLPGEKGHRGDTGAQGLP 582 Query: 503 GEPGRFGVNSSDVP-GPAGLPGVPGRE---GPPGFPGLPGPPGPPGREGPPGRTGQKGSL 558 G PG G D GP GLPG G GP G PG+PGPPG G +GP G G G Sbjct: 583 GPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQ 642 Query: 559 GEAGAPGHK---GSKGAPGPAGA---RGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFD 612 GE G PG + G++G PGP GA GE G G PG G PG GPPG PG P G Sbjct: 643 GEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTK 702 Query: 613 DMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFP------- 665 +G GP GP G PG G+KG G+ GL G KGE G DG PGF Sbjct: 703 GNQGPSGP--------QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKG 754 Query: 666 -----GLPGREGIAGPQGPKGDRGSRGEKGDPG----KDGVGQPGLPGPPGPPGPVVYVS 716 G+PG G GP+GPKG G G+ G PG K +G PGLPG PG GP Sbjct: 755 DRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGP----- 809 Query: 717 EQDGSV--LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGS------- 767 GS+ PG G G G G +GP+G G G RG GP+G G+ G+ Sbjct: 810 --KGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGD 867 Query: 768 -IFSPDGGALGPAQKGAKGEPGFRGPPGPYGR------PGYKGEIGFPGRPGRPGMNGLK 820 P G P +G G PG +GPPGP G+ PG +GE+GF G+ G PG G+ Sbjct: 868 GPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVV 927 Query: 821 GEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPG 880 G +G G+ G RG PGPPGPPG G PGT + PGPPG PG GP G Sbjct: 928 GPQGAAGETG-PMGERGHPGPPGPPGEQGLPGTAGKEGT----KGDPGPPGAPGKDGPAG 982 Query: 881 PKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFG-SSLPG 939 +G GE G PG G +G G G AG GERG G GG G PG Sbjct: 983 LRGFPGERGLPGTAGGPGL------KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPG 1036 Query: 940 PPGPPGPRGYPGIPGPKG-------ESIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPG 991 P GPPG G G+PG KG + ++G G PGP GPPG+ G +G +G G PG G Sbjct: 1037 PQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKG 1096 Query: 992 PPSFPGPHRQTISVPGPPGPPGPPGPPGTMGA 1023 G H PGPPGP GP G PG GA Sbjct: 1097 TKGNKGEH----GPPGPPGPIGPVGQPGAAGA 1124 Score = 491 bits (1264), Expect = e-138 Identities = 341/853 (39%), Positives = 400/853 (46%), Gaps = 131/853 (15%) Query: 239 EEGDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEE 298 E G D D G GD REET L P L A T A + E+ Sbjct: 334 EGGTDPPEGPYDYTYGYGDD---YREET--ELGPALSAE---TAHSGAAAHGPRGLKGEK 385 Query: 299 VEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPG 358 E + + PG + + G + PG + G G G+PG GPPGRAG PG Sbjct: 386 GEPAVLEPGMLVEGPPGPEGPA---GLIGPPGIQ----GNPGPVGDPGERGPPGRAGLPG 438 Query: 359 SPCLPGPPGLPCPV-----SPLGPAGPAL------------QTVPGPQGPPGPPGRDGTP 401 S PGPPG + S G GP + Q +GPPGP G G P Sbjct: 439 SDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRP 498 Query: 402 GRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSF 461 G G+PG PG G+ GD GPQG G G GP G G G G G +G PG PG Sbjct: 499 GPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRG--RAGADGARGMPGDPG--V 554 Query: 462 RHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGL 521 + D+ GF G L L G +G G G G+PG PGE G G + GP GL Sbjct: 555 KGDR---------GFDG-LPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI--GPRGL 602 Query: 522 PGVPGREG---PPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGS---KGAPGP 575 PG G G P G PG+PGPPG G +GP G G G GE G PG +G+ +G PGP Sbjct: 603 PGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGP 662 Query: 576 AGA---RGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQ 632 GA GE G G PG G PG GPPG PG P G +G GP GP Sbjct: 663 QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGP--------QGPL 714 Query: 633 GPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPG------------LPGREGIAGPQGPK 680 G PG G+KG G+ GL G KGE G DG PGF G +PG G GP+GPK Sbjct: 715 GYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPK 774 Query: 681 GDRGSRGEKGDPG----KDGVGQPGLPGPPGPPGPVVYVSEQDGSV--LSVPGPEGRPGF 734 G G G+ G PG K +G PGLPG PG GP GS+ PG G G Sbjct: 775 GRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGP-------KGSLGFPGFPGASGEKGA 827 Query: 735 AGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDG-------GALG-PAQKGAKGE 786 G G +GP+G G G RG GP+G G+ G+ + G G G P +G G Sbjct: 828 RGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGF 887 Query: 787 PGFRGPPGPYGR------PGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPG 840 PG +GPPGP G+ PG +GE+GF G+ G PG G+ G +G G+ G RG PG Sbjct: 888 PGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG-PMGERGHPG 946 Query: 841 PPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFD 900 PPGPPG G PGT + PGPPG PG GP G +G GE G PG G Sbjct: 947 PPGPPGEQGLPGTAGKEGT----KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLK 1002 Query: 901 FLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIPGPKG-- 957 +G G G AG GERG G GG G PGP GPPG G G+PG KG Sbjct: 1003 ------GNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPI 1056 Query: 958 -----ESIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGP 1011 + ++G G PGP GPPG+ G +G +G G PG G G H GPPGP Sbjct: 1057 GPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEH-------GPPGP 1109 Query: 1012 PGPPGPPGTMGAS 1024 PGP GP G GA+ Sbjct: 1110 PGPIGPVGQPGAA 1122 Score = 489 bits (1258), Expect = e-138 Identities = 323/767 (42%), Positives = 366/767 (47%), Gaps = 125/767 (16%) Query: 338 LKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVP----------- 386 L+G G G G PG G PGSP L G G + P GP GP T P Sbjct: 485 LRGPPGPMGYTGRPGPLGQPGSPGLKGESG---DLGPQGPRGPQGLTGPPGKAGRRGRAG 541 Query: 387 --GPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-- 442 G +G PG PG G G DG PG PGE G GDTG QG PG PG+ G +GD G+ G Sbjct: 542 ADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRG 601 Query: 443 -----GERGPPGPQGPPGPPGPSFRHDKLTFIDMEG-SGFGGDLEALRGPRGFPGPPGPP 496 G RG GP+GPPG PGP M+G G G L GP+G PGPPG Sbjct: 602 LPGESGPRGLLGPKGPPGIPGPPGVRG------MDGPQGPKGSL----GPQGEPGPPGQQ 651 Query: 497 GVPG---LPGEPGRFGVNSSDVP-GPAGLPGVPGREGPPGFPGLPGPPGPPGREGP---- 548 G PG LPG G G + P G GLPG+PG +GPPG PG GPPG G +GP Sbjct: 652 GTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQ 711 Query: 549 -----PGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPP 603 PG G KG G G GHKG KG G G +G+ G+ G G G PG G GP Sbjct: 712 GPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPE 771 Query: 604 GPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPG 663 GP +G GP G GPPGL G KG GVPGLPG G G G G Sbjct: 772 GP---------KGRTGP--------TGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLG 814 Query: 664 FPGLPG------------REGIAGPQGPKGDRGSRGEKGDPGKDGV-GQPGLPGPPGPPG 710 FPG PG + G G +GP G RG RG +G GK G G G GP GPPG Sbjct: 815 FPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPG 874 Query: 711 PVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGN---LGSKGERGSPGPKGEKGEPG- 766 +PGP+G GF G GP GP G G G+RG G +G+ G PG Sbjct: 875 E-----------RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP 923 Query: 767 -SIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPG---------M 816 + P G A G +G PG GPPG G PG G+ G G PG PG + Sbjct: 924 PGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGL 983 Query: 817 NGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQ 876 G GE+G PG A G G++G GP GPPGP G PG + GPPG PG Q Sbjct: 984 RGFPGERGLPGTAG-GPGLKGNEGPSGPPGPAGSPG----ERGAAGSGGPIGPPGRPGPQ 1038 Query: 877 GPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSS 936 GPPG G KG G GP G D +Q + G G G AG+ G++GE G G G+ Sbjct: 1039 GPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTK 1098 Query: 937 ----LPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPG 991 GPPGPPGP G G PG G G+PG GPQG G G EG +G GPPGP G Sbjct: 1099 GNKGEHGPPGPPGPIGPVGQPGAAGAD--GEPGARGPQGHFGAKGDEGTRGFNGPPGPIG 1156 Query: 992 PPSFPGPHRQT--------ISVPGPPGP---PGPPGPPGTMGASSGV 1027 PGP + + PGPPGP GP G G G GV Sbjct: 1157 LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGV 1203 Score = 432 bits (1112), Expect = e-121 Identities = 306/763 (40%), Positives = 350/763 (45%), Gaps = 146/763 (19%) Query: 309 GAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGL 368 GA G+ S DG PG R GL G +G G PGP G GPPG LPG PG Sbjct: 853 GATGKSGAKGTSGGDGPHGPPGER----GLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQ 908 Query: 369 ------------PCPVSPLGPAGPALQTVP----GPQGPPGPPGRDGTPG---RDGEPGD 409 P P +GP G A +T P G GPPGPPG G PG ++G GD Sbjct: 909 RGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD 968 Query: 410 PGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTF 468 PG G PG GP G G PG+ G G G PG+ G GP GP GP G PG Sbjct: 969 PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG---------- 1018 Query: 469 IDMEGSGFGGDLEALRGPRGFPGPPGPPGVPG---LPGEPGRFGVNSSD-------VPGP 518 + +G GG + GP G PGP GPPG G +PGE G G D +PGP Sbjct: 1019 -ERGAAGSGGPI----GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGP 1073 Query: 519 AGLPGV------------PGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGH 566 AG PGV PG++G G G GPPGPPG GP G+ G G+ GE GA G Sbjct: 1074 AGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGP 1133 Query: 567 KGSKGAPGPAGARGESG------LAGAPGPAGPPG------PPGPPGPPGPGLPAGFDDM 614 +G GA G G RG +G L G PGP+G G P GPPGPPGP PAG + Sbjct: 1134 QGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGA 1193 Query: 615 EGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIA 674 +G GP GP G G PG G PG+ G PG KG G G G G PG G Sbjct: 1194 DGPQGPPGGVGNL--GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1251 Query: 675 GPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGF 734 GP+GP GD G KG+PG VG PG PGPPG GP QDG+ G +G PG Sbjct: 1252 GPKGPTGDDGP---KGNPGP--VGFPGDPGPPGEGGP----RGQDGAK-GDRGEDGEPGQ 1301 Query: 735 AGFPGPAG---PKGNLGSKGERGSPGP------KGEKGEPGSIFSPDG----GALGPAQK 781 G PGP G P G LG +G GSPG KG KG+PG+I +P G GPA K Sbjct: 1302 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1361 Query: 782 -------------------GAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGE 822 GA G+ G GP GP G PG +G+ G G G PG+ GL G Sbjct: 1362 PGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGP 1421 Query: 823 KGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPK 882 GE G+ G RG+PGP G PG G G P + GPPGLPG GP G K Sbjct: 1422 PGEQGEK----GDRGLPGPQGSPGQKGEMGIPGASGPI----GPGGPPGLPGPAGPKGAK 1473 Query: 883 GAKGEVGP------------PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGG 930 GA G GP PGPPG+ L ++ K + G + + P GG Sbjct: 1474 GATGPGGPKGEKGVQGPPGHPGPPGEV-IQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGG 1532 Query: 931 GFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPP 973 PG PG G G E I P G Q P Sbjct: 1533 A------PGSPG--GLEEIFGSLDSLREEIEQMRRPTGTQDSP 1567 Score = 380 bits (975), Expect = e-105 Identities = 264/644 (40%), Positives = 293/644 (45%), Gaps = 111/644 (17%) Query: 263 REETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTW 322 R E G K P PP V P A G E E G Q LPG+ Sbjct: 909 RGEVGFQGKTGPPGPPGVVGPQGAAG---ETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 965 Query: 323 DGSVRTPGGRVKEG-----------GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP 371 G PG K+G GL G G PG+ G G +GPPG PG G Sbjct: 966 KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 1025 Query: 372 VSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG---PQGFPGTP 428 P+GP G PGPQGPPG G G PG G G G DG G G P G PG Sbjct: 1026 GGPIGPPGR-----PGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA 1080 Query: 429 GDVGPKGDKGDPGV-------GERGPPGPQGPPGP---PGPSFRHDKLTFIDMEGS-GFG 477 G+ G KG+ GDPG GE GPPGP GP GP PG + + +G G Sbjct: 1081 GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK 1140 Query: 478 GDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLP 537 GD G RGF GPPGP G+ GLPG G G + DV GP G PG PG GP G G Sbjct: 1141 GD----EGTRGFNGPPGPIGLQGLPGPSGEKG-ETGDV-GPMGPPGPPGPRGPAGPNGAD 1194 Query: 538 GPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPP 597 GP GPPG G G G+KG GE+G+PG +G G GP G RGE G +G PG GPPGP Sbjct: 1195 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK 1254 Query: 598 GP------------------PGPPGPGLPAGFDDMEGSGG----PFWSTARSADGPQGPP 635 GP PGPPG G P G D +G G P + G GPP Sbjct: 1255 GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPP 1314 Query: 636 GLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKD 695 G G +G G PG G +G GA G PG G PG+ G GP GP G G G +G PG Sbjct: 1315 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1374 Query: 696 GV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERG 754 G G+PG G GPPGPV GP G PG G G G KG+ G G G Sbjct: 1375 GQQGRPGATGQAGPPGPV--------------GPPGLPGLRGDAGAKGEKGHPGLIGLIG 1420 Query: 755 SPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGP---------PGPYGRPGYKGEI 805 PG +GEKG+ G + P G P QKG G PG GP PGP G G KG Sbjct: 1421 PPGEQGEKGDRG-LPGPQGS---PGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGAT 1476 Query: 806 GFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPG 849 G PG P KGEK G+ GPPG PGPPG Sbjct: 1477 G-PGGP--------KGEK-------------GVQGPPGHPGPPG 1498 >gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] Length = 1690 Score = 514 bits (1325), Expect = e-145 Identities = 345/830 (41%), Positives = 398/830 (47%), Gaps = 127/830 (15%) Query: 275 PAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVK 334 P PP PP G + S + + + G DG PG + Sbjct: 529 PGPPGAEGPP---GLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPG-QPG 584 Query: 335 EGGLKGQKGEPGVPGPPG--RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPP 392 G G GE G PGPPG PG PGP G P P+GP G PG +G P Sbjct: 585 SHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHP 644 Query: 393 GPPGRDGTPGRDGEPGDPGEDGK-----PGDTGPQGFPGTPGDVGPKGDKGDPGV----G 443 G PG G G DG G G+ PG GP GF G PG G G +G PG+ G Sbjct: 645 GVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDG 704 Query: 444 ERGPPGPQGP---PGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPG 500 +G PG G PGPPG FR D M GFGG+ + P G PGPPG PGV G Sbjct: 705 HKGRPGTPGTAEIPGPPG--FRGD------MGDPGFGGEKGS--SPVGPPGPPGSPGVNG 754 Query: 501 LPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP------GREGPPGRTGQ 554 G PG PG GL GVPG +GP G PG PG GP G +GP GR G Sbjct: 755 QKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGH 814 Query: 555 KGSLGEAGAPGH---KGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGL 607 G G G PGH +G+ G PG G G G GAPG G PG GPPGP G PGL Sbjct: 815 AGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGL 874 Query: 608 PA-----GFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVP 662 P G + G GPF DG GPPG G +G PG PG PG +G+ GA+G P Sbjct: 875 PGRPGAHGPPGLPGIPGPF-----GDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCP 929 Query: 663 GFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG----VGQPGLPGPPGPPGPVVYVSEQ 718 G G PG +G++G G +G RG++G G PG +G + Q G PG PGPPG + E+ Sbjct: 930 GAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGER 989 Query: 719 DGSVLSVPGPEGR---------PGF----------AGFPGPAGPKGNLGSKGERGSPGPK 759 PG +GR PGF G PGP GP G+ G +G G PG Sbjct: 990 GDK--GTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLP 1047 Query: 760 GEKGEPGSI----FSPDGGALGPAQKGAKGEPGFR-GPPGPYGRPGYKGEIGFPGRPGRP 814 G++GEPGS FS GA GP KG KG+P GPPGP KGE PG PG P Sbjct: 1048 GDQGEPGSPGPPGFSGIDGARGP--KGNKGDPASHFGPPGP------KGE---PGSPGCP 1096 Query: 815 GMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPG 874 G G GE+G PG G RG PG PGPPG GPPG P + PG G PG Sbjct: 1097 GHFGASGEQGLPGIQ----GPRGSPGRPGPPGSSGPPGCP-------GDHGMPGLRGQPG 1145 Query: 875 NQGPPGPKGAKGEVGPPGPPG-QFPFDFLQLEA--EMKGEKGDRGDA------------- 918 G PGP+G +G+ G PGPPG + P L +KG+KG +G + Sbjct: 1146 EMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGI 1205 Query: 919 -GQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRG-----QPGPPGPQGP 972 G KGERG+PG G G GPPGP G G PGP G + R PGPPG QGP Sbjct: 1206 PGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGP 1265 Query: 973 PGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1022 P G +G +G PGPPG PG +PGPPGPPGPPGPPG G Sbjct: 1266 P--GPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKG 1313 Score = 512 bits (1318), Expect = e-144 Identities = 357/877 (40%), Positives = 408/877 (46%), Gaps = 153/877 (17%) Query: 267 GAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSV 326 GA P LP + PP G+ + S + G PG DG Sbjct: 533 GAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHA 592 Query: 327 RTPGGRVKEG----GLKGQKGEPGVPGPPGRAGPPGSPCL--PGPPG------LPCPVSP 374 G G G KG PG GPPG+AGP G P L PGPPG +P Sbjct: 593 GEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGV 652 Query: 375 LGPAGPALQ---------TVPGPQGPPG---PPGRDGTPGRDGEPGDPGEDGKPGDTGPQ 422 GP G Q T PG GPPG PPG G PG G PG G DG G G Sbjct: 653 RGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTP 712 Query: 423 GFPGTPGDVGPKGDKGDPGVG-ERG--PPGPQGPPGPPG----------PSFRHDKLTFI 469 G PG G +GD GDPG G E+G P GP GPPG PG P+F H + Sbjct: 713 GTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGH-----L 767 Query: 470 DMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPG--- 526 G + ++GPRG PG PG G G+PG G G + G AG PGVPG Sbjct: 768 GPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGRE--GHAGFPGVPGPPG 825 Query: 527 ---REGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESG 583 G PG PG PG PG PG G PG GQ G +G G G KG G PG GA G G Sbjct: 826 HSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPG 885 Query: 584 LAGAPGPAGPPGPPGPPGPPGP-GLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKG 642 L G PGP G G PGPPGP GP GLP GF G G A G +G PG G+ G Sbjct: 886 LPGIPGPFGDDGLPGPPGPKGPRGLP-GFPGFPGERGK--PGAEGCPGAKGEPGEKGMSG 942 Query: 643 DPGVPGLPGAKGEVGADG------------VPGFPGLPGREGIAGPQGPKGDRGSRGEKG 690 PG GL GAKG +G G PG PG PG +G G +G KG G +G +G Sbjct: 943 LPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRG 1002 Query: 691 DPGKDGV--------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAG 742 +PG+ G G+ G PGPPGPPGP PG G GF GFPG G Sbjct: 1003 EPGRYGPPGFHRGEPGEKGQPGPPGPPGP--------------PGSTGLRGFIGFPGLPG 1048 Query: 743 PKGNLGSKGERG------SPGPKGEKGEPGSIFSPDG-----GALG-PAQKGAKGE---P 787 +G GS G G + GPKG KG+P S F P G G+ G P GA GE P Sbjct: 1049 DQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLP 1108 Query: 788 GFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGP 847 G +GP G GRPG G G PG PG GM GL+G+ GE GD G++G PG PGPPG Sbjct: 1109 GIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPR-GLQGDPGIPGPPGI 1167 Query: 848 PGPPGTPVYDSNVFAESSRPGPPGLPG--NQGPPGP---KGAKGEVGPPGPPGQFPFDFL 902 GP G+P + + + G G G + GPPGP G KGE G PG PG P Sbjct: 1168 KGPSGSPGLNG-LHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISP---- 1222 Query: 903 QLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSS---LP--------GPPGPPGPRGYPG 951 G +G +G G G G PG G G + +P GPPGP GPRG PG Sbjct: 1223 ------PGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPG 1276 Query: 952 IPGPKGE-----------SIRGQPGPPGPQGPPGI-------GYEGRQGPPGPPGPPGPP 993 PG G + G PGPPGP GPPG G +G++GP G PGP GP Sbjct: 1277 PPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPH 1336 Query: 994 SFPGPHRQTISVPGPPG---PPGPPGPPGTMGASSGV 1027 FPGP + +PGPPG P G PGP G G + V Sbjct: 1337 GFPGPPGEK-GLPGPPGRKGPTGLPGPRGEPGPPADV 1372 Score = 491 bits (1265), Expect = e-138 Identities = 352/876 (40%), Positives = 396/876 (45%), Gaps = 176/876 (20%) Query: 306 ASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGS------ 359 A+ G + PG G V PG + G G++G PGVPG PG GP G Sbjct: 607 ATPGGKGFPGPLGPPGKAGPVGPPG--LGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGD 664 Query: 360 --------PCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPG 411 P GPPG P P G GP Q PG G G GR GTPG PG PG Sbjct: 665 TISCNVTYPGRHGPPGFDGPPGPKGFPGP--QGAPGLSGSDGHKGRPGTPGTAEIPGPPG 722 Query: 412 EDGKPGD-----------TGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPS 460 G GD GP G PG+PG G KG GDP G GPPG +G G PG Sbjct: 723 FRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIK 782 Query: 461 FRHDKLTFIDMEG-SGFGGDLEALRGPRG------FPGPPGPPG------VPGLPGEPGR 507 EG +G G L L+GP+G FPG PGPPG PG+PG+PG Sbjct: 783 GPRGDPGCPGAEGPAGIPGFL-GLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGL 841 Query: 508 FGVNSS-----------DV--PGPAG------LPGVPGREGPPGFPGLPGP------PGP 542 G S DV PGPAG LPG PG GPPG PG+PGP PGP Sbjct: 842 PGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGP 901 Query: 543 PGREGP------PGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGP 596 PG +GP PG G++G G G PG KG G G +G G+ GL GA G GPPG Sbjct: 902 PGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGD 961 Query: 597 PGP---------PGPPGPGLPAGFDDMEGSGG-PFWSTARSADGPQGPPGL----PGLKG 642 G PG PGP GF G G P R G GPPG PG KG Sbjct: 962 EGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKG 1021 Query: 643 DPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKG------DRGSRGEKGDPGKDG 696 PG PG PG G G G GFPGLPG +G G GP G RG +G KGDP Sbjct: 1022 QPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASH- 1080 Query: 697 VGQPGLPGPPGPPG-PVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGN--------- 746 G PG G PG PG P + + + + + GP G PG G PG +GP G Sbjct: 1081 FGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGL 1140 Query: 747 LGSKGERGSPGPKGEKGEPGSIFSPDGGALGPA-------------QKGAKGEPGFR--G 791 G GE G PGP+G +G+PG P G GP+ QKG KG G G Sbjct: 1141 RGQPGEMGDPGPRGLQGDPGIPGPP--GIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVG 1198 Query: 792 PPGPYGRPGYKGEIGFPGRPG--RPGMNGLKGEKGEPGDA-------SLGFGMRGMP--G 840 PPGP G PG KGE G PG PG PG G KG G PG + + G + +P G Sbjct: 1199 PPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPG 1258 Query: 841 PPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGN----QGPPGPKGAKGEVGPPGPPGQ 896 PPG GPPGP G PGPPGLPG+ +G PG G G GPPGPPG Sbjct: 1259 PPGDQGPPGPDGP----------RGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGP 1308 Query: 897 FPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYP---GIP 953 + G+KG G G +G G PG G G LPGPPG GP G P G P Sbjct: 1309 PGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKG--LPGPPGRKGPTGLPGPRGEP 1366 Query: 954 GPKGE-----SIRGQPGPPGPQGPPGI------------------GYEGRQGPPGPPGPP 990 GP + I G PG PG +GP G G +GR+G G PG P Sbjct: 1367 GPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSP 1426 Query: 991 GPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSG 1026 GPP G + PG PGPPGP G PG G G Sbjct: 1427 GPPGRKGDTGED-GYPGGPGPPGPIGDPGPKGFGPG 1461 Score = 466 bits (1199), Expect = e-131 Identities = 378/1011 (37%), Positives = 433/1011 (42%), Gaps = 279/1011 (27%) Query: 265 ETGAALKPRLPAPP----PVTTPPLAGGSSTEDSRSEE-----VEEQTTVASLGAQTLPG 315 E G+ P P P P+ P G S + R + ++ G PG Sbjct: 60 EKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPG 119 Query: 316 SDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSPCLPGP-------- 365 D + G PG R K G G G +G+PG PG G GP G PG Sbjct: 120 LDGIPGHPGP---PGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSV 176 Query: 366 ------------------PGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEP 407 PGLP GPAGP PG G GPPG+ G PG G P Sbjct: 177 FILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPT--GYPGEPGLVGPPGQPGRPGLKGNP 234 Query: 408 G--------DPGEDGKPGDTGP------------------QGFPGTPGDVGPKGDKGDPG 441 G DPGE G+ G GP +G PG G GP G KG+ G Sbjct: 235 GVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESG 294 Query: 442 VGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS-GFGGD--LEALRGPRGFPGP---PGP 495 +G +G G G PGP G + F ++G G GD L L GP+G PG PGP Sbjct: 295 IGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGP 354 Query: 496 PGV-----------PGLPGEPGRFGVNSSDV--PGPAGLPGVPGRE--------GPPGFP 534 PGV PG PG PGR+G + DV PGP GL G PG GP GFP Sbjct: 355 PGVLVTPPLPLKGPPGDPGFPGRYG-ETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFP 413 Query: 535 GLPGPPGP---PGR-EGPPGRTGQKGSLGEAGAPGHKG---------SKGAPGPAGARGE 581 GLPG PG PGR + PG+ G+ GS G GAPG +G S G PGP G +G+ Sbjct: 414 GLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGK 473 Query: 582 SGLAGAPGPAGP----------PGPPGPPGPPG-PGLPAGFDDMEGSGGPFWSTARSADG 630 G G GP G PGP GPPGPPG PG D+ G P W + G Sbjct: 474 VGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDL---GLPGWLGTKGDPG 530 Query: 631 P---QGPPGLPGLKGDPGVPGLPGAKGEV------------GADGVPGFPGLPGREGIAG 675 P +GPPGLPG G G PG GAKG++ G DG PGFPG PG G G Sbjct: 531 PPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDG 590 Query: 676 PQGPKGDRGSRGEK--------------GDPGKDG-VGQPGL--PGPPGPPG-------P 711 G KGD G G+ G PGK G VG PGL PGPPG G P Sbjct: 591 HAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHP 650 Query: 712 VVY----VSEQDGSVLSV----PGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKG 763 V + Q G +S PG G PGF G PGP G G G+ G GS G KG G Sbjct: 651 GVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPG 710 Query: 764 EPGSIFSPDGGALGPAQKGAKGEPGFRG--------PPGPYGRPGYKGEIGFPGRP---- 811 PG+ P P +G G+PGF G PPGP G PG G+ G PG P Sbjct: 711 TPGTAEIPGP----PGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGH 766 Query: 812 -------GRPGMNGLKGEKGEPGDASL-------GF----GMRGMPGPPGPPGPPGPPGT 853 G G+ G+KG +G+PG GF G +G G G PG PGPPG Sbjct: 767 LGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGH 826 Query: 854 PVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKG 913 + +PG PG PG+ G PG KG G+VGPPGP G MKG G Sbjct: 827 SC-ERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAG------------MKGLPG 873 Query: 914 DRGDAGQKGERGEPGGGGFFGSS-LPGPPGPPGPRGYPGIPGPKGESIRGQPGP---PGP 969 G G G G PG G FG LPGPPGP GPRG PG PG GE RG+PG PG Sbjct: 874 LPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGE--RGKPGAEGCPGA 931 Query: 970 QGPPG-------------------IGYEG---------RQGPPGPPGPPGPPSFPGP--- 998 +G PG IG G ++G PG PGPPG FPG Sbjct: 932 KGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGD 991 Query: 999 ---------------------HRQTISVPGPPGPPGPPGPPGTMGASSGVR 1028 HR PG G PGPPGPPG G S+G+R Sbjct: 992 KGTPGMQGRRGEPGRYGPPGFHR---GEPGEKGQPGPPGPPGPPG-STGLR 1038 Score = 407 bits (1047), Expect = e-113 Identities = 287/720 (39%), Positives = 332/720 (46%), Gaps = 148/720 (20%) Query: 309 GAQTLPGSDSVSTWDGSVRTPGGRVKEG-----GLKGQKGEPGVPGPPGRAGPPGSPCLP 363 GA +PG + + GS PGG+ + G G G KG PG+PG PG GPPG P +P Sbjct: 831 GAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIP 890 Query: 364 GP---PGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG 420 GP GLP P P GP G L PG G G PG +G PG GEPG+ G G PGD Sbjct: 891 GPFGDDGLPGPPGPKGPRG--LPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGD-- 946 Query: 421 PQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPG-PSFRHDKLTFIDMEGS---- 474 +G G G +GP GD+G+ + ++G PG GPPG G P R DK T M+G Sbjct: 947 -RGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGT-PGMQGRRGEP 1004 Query: 475 ---GFGGDLEALRGPRGFPGPPGPPGVPG---------LPGEPGRFGVNSSDVPGPAGLP 522 G G G +G PGPPGPPG PG PG PG G S PGP G Sbjct: 1005 GRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGS--PGPPGFS 1062 Query: 523 GVPGREGPPGFPGLP----GPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGA 578 G+ G GP G G P GPPGP G G PG G G+ GE G PG +G +G+PG G Sbjct: 1063 GIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGP 1122 Query: 579 RGESG------------LAGAPGPAGPPGP------PGPPGPPG-------PGLPAGFDD 613 G SG L G PG G PGP PG PGPPG PGL G Sbjct: 1123 PGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLN-GLHG 1181 Query: 614 MEGSGGPFWSTARSADGPQGPPGLPGLK---GDPGVPGL--PGAKGEVGADGVPGFPGLP 668 ++G G ++ GP GP G+PGLK GDPG PG+ PG +G+ G G PG G P Sbjct: 1182 LKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPP 1241 Query: 669 GREGIA-------------GPQGPKGDRGSRGEKGDPGKDG-----------VGQPGLPG 704 G G G QGP G G RG G PG G G PG PG Sbjct: 1242 GPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPG 1301 Query: 705 PPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGE 764 PPGPPGP Y G +G+ G GFPGP GP G G GE+G PGP G KG Sbjct: 1302 PPGPPGPPGY-----KGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKG- 1355 Query: 765 PGSIFSPDGGALGPAQ-------KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMN 817 P + P G PA G G PG RGP G G PG +G G PG G PG++ Sbjct: 1356 PTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSG-PGCKGEPGLD 1414 Query: 818 GLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQG 877 G + G+ G+PG PGPPG G G E PG PG PG G Sbjct: 1415 GRR-------------GVDGVPGSPGPPGRKGDTG----------EDGYPGGPGPPGPIG 1451 Query: 878 PPGPKG-AKGEVG----------------PPGPPGQFP-FDFLQLEAEMKGEKGDRGDAG 919 PGPKG G +G P G P + + L LE + K D G AG Sbjct: 1452 DPGPKGFGPGYLGGFLLVLHSQTDQEPTCPLGMPRLWTGYSLLYLEGQEKAHNQDLGLAG 1511 Score = 301 bits (770), Expect = 4e-81 Identities = 212/507 (41%), Positives = 236/507 (46%), Gaps = 83/507 (16%) Query: 574 GPAGARG--------ESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTA 625 GP G R E G G PGP GP GP GP G PGP +G M G GP + Sbjct: 45 GPCGGRDCSVCHCVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAG 104 Query: 626 RSAD-GPQGPPGLPGLKGDPGVPGLPGAKGEVGA---DGVPGFPGLPGREGIAGPQGPKG 681 D GP G PG PGL G PG PG PG +G+ G +G G PG PG G GP GP G Sbjct: 105 DKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLG 164 Query: 682 DRGSRGEKGDP--------GKDGV-GQPGLPGPPG------PPGPVVYVSEQDGSVLSVP 726 G +GEKG+ G G G PGLPG PG P GP Y E ++ P Sbjct: 165 HPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEP--GLVGPP 222 Query: 727 GPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGS--IFSPDGGALGPAQKGAK 784 G GRPG G PG +G KG+ G PG G++G PG + P L +KG K Sbjct: 223 GQPGRPGLKGNPG-------VGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIK 275 Query: 785 GEPGFRGPPGPYGR--------------PGYKGEIGFPGRPGRPGMNGLKGEKGEPGDAS 830 G PG G PGP GR PG+ G G PG G PG GLKGE G GD Sbjct: 276 GIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPG 335 Query: 831 LGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGP-PGLPGNQGPPGPKGAKGEVG 889 L FG+ G G PG G PGPPG V + P P G PG+ G PG G G+VG Sbjct: 336 L-FGLIGPKGDPGNRGHPGPPGVLV---------TPPLPLKGPPGDPGFPGRYGETGDVG 385 Query: 890 PPGPPGQFPFDFLQLEAEM-KGEKGDRGDAGQKGERGEPGGGGFFG--SSLPGPPGPPGP 946 PPGPPG L E G G G G G G PG G G S PG PG PG Sbjct: 386 PPGPPG-----LLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGS 440 Query: 947 RGYPGIPG----PKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQT 1002 G PG PG P I G PGPQG +G+ GPPG GP G G Sbjct: 441 PGLPGAPGLQGLPGSSVIYCSVGNPGPQG-----IKGKVGPPGGRGPKGEKGNEG---LC 492 Query: 1003 ISVPGPPGPPGPPGPPGTMGASSGVRL 1029 PGP GPPGPPG PG G+ + L Sbjct: 493 ACEPGPMGPPGPPGLPGRQGSKGDLGL 519 Score = 191 bits (486), Expect = 3e-48 Identities = 145/357 (40%), Positives = 163/357 (45%), Gaps = 53/357 (14%) Query: 714 YVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDG 773 Y+ G SV G G PGP GP+G +G G G G GEKG G P G Sbjct: 43 YIGPCGGRDCSVCHCVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGD-RGPPG 101 Query: 774 GALGPAQKGAKGEPGF---------RGPPGPYGRPGYKGEIGFPGRPGRPGMNGL----- 819 A KG G PGF GPPGP G+PG G G G PG PG G Sbjct: 102 AAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGG 161 Query: 820 ----KGEKGEPGDASLGFG-MRGMPGPPGPPGPPGPPGT-----PVYDSNVFAESSRPGP 869 GEKGE G++ G ++G+ G G PG PG PG+ P + E GP Sbjct: 162 PLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGP 221 Query: 870 PGLPGNQGPPGPK--GAKGEVGPPGPPGQ--FPFDFLQLEAE----MKGEKGDRGDAGQK 921 PG PG G G G KG++G PG GQ P L +E KGEKG +G G Sbjct: 222 PGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMV 281 Query: 922 GERGEPGGGGFFG---------SSLPGPPGPPGPRGYPGIPGPKGE-SIRGQPGPPGPQG 971 G G PG G G PGP G PG G PG PG KGE + G PG G G Sbjct: 282 GLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIG 341 Query: 972 PPG-IGYEGRQGPPG----PP----GPPGPPSFPGPHRQTISVPGPPGPPGPPGPPG 1019 P G G G GPPG PP GPPG P FPG + +T V GPPGPPG G PG Sbjct: 342 PKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDV-GPPGPPGLLGRPG 397 Score = 122 bits (307), Expect = 2e-27 Identities = 87/223 (39%), Positives = 96/223 (43%), Gaps = 29/223 (13%) Query: 238 DEEGDDSDGASGDSGS-GLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRS 296 D+ DG G G GL + +LLR E G P P PP PP Sbjct: 1262 DQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPP------------ 1309 Query: 297 EEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGP 356 G + PG D G V PG + G G GE G+PGPPGR GP Sbjct: 1310 ------------GYKGFPGCDGKDGQKGPVGFPGPQGPH-GFPGPPGEKGLPGPPGRKGP 1356 Query: 357 PGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKP 416 G P G PG P V P P L PG +GP G G G G G PG GE G Sbjct: 1357 TGLPGPRGEPGPPADVDDC-PRIPGLPGAPGMRGPEGAMGLPGMRGPSG-PGCKGEPGLD 1414 Query: 417 GDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPG 458 G G G PG+PG G KGD G+ G G GPPGP G PGP G Sbjct: 1415 GRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKG 1457 >gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] Length = 1745 Score = 514 bits (1325), Expect = e-145 Identities = 344/829 (41%), Positives = 401/829 (48%), Gaps = 114/829 (13%) Query: 283 PPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQK 342 PP G + E + + + G + G D G+V PG G +G Sbjct: 588 PPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPG-EPGPPGQQGNH 646 Query: 343 GEPGVPGP------PGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPG--- 393 G G+PGP PG GPPG+P +PG PG P+ G GP + G QGPPG Sbjct: 647 GSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEK--GAQGPPGSAG 704 Query: 394 PPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQG 452 PPG G G G G+ G G+ G+ G GFPG GDVG KGD+G PG G RG GP+G Sbjct: 705 PPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEG 764 Query: 453 PPG---------PPGPSFRHDKLTFIDMEGS----------GFGGDL------------- 480 P G PPG + KL + G GF G L Sbjct: 765 PKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTG 824 Query: 481 -EALRGPRGFPGPPGPPGVPGLPGEPGRFG-VNSSDVPGPAGLPGVPGREGPPGFPGLPG 538 L G RG PG G G PG G+PG G V PG G G+PG +GPPGFPG G Sbjct: 825 QPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKG 884 Query: 539 PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPG 598 PPG G++G PG GQ+G L G +G G PGPAG G G G GP G GPPG Sbjct: 885 PPGHQGKDGRPGHPGQRGEL------GFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPG 938 Query: 599 PPGPPG-PGLPAGFDDMEGSGGPFWSTA-RSADGPQGPPGLPGLKGDPGVPGLPGAKGE- 655 PPGPPG GLP G + EG+ G +GP G G PG KG PG PG G KG+ Sbjct: 939 PPGPPGEQGLP-GLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDK 997 Query: 656 -----VGADGVPGFP---------GLPGREGIAGPQGPKGDRGSRGEKGDPGKDGV-GQP 700 VGA+G PG GLPG+ G GP GP G +GSRGE+G PG G G P Sbjct: 998 GPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIP 1057 Query: 701 GLPGPPGPPGPVVYVSEQ-DGSVLSVP------------GPEGRPGFAGFPGPAGPKGNL 747 G GP GPPG E+ D + P GP G+PG G G GP G Sbjct: 1058 GPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGAD 1117 Query: 748 GSKGERGSPGPKGEKGEPG-----SIFSPDG--GALG-PAQKGAKGEPGFRGP---PGPY 796 G++G RG PG G+KG+ G + P G G G P +KG G+ G GP PGP Sbjct: 1118 GAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPR 1177 Query: 797 GRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVY 856 G G G G PG PG G G GEKGE GDA G PGPPG PG PGP G Sbjct: 1178 GPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDA-------GDPGPPGAPGIPGPKG---- 1226 Query: 857 DSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRG 916 D +S G G PG +GPPG GAKG VGP G PG + + G G++G Sbjct: 1227 DIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKG 1286 Query: 917 DAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-I 975 D G G G PG G G+ PGPPG GP G+ G G +GE +G G PGP GPPG Sbjct: 1287 DPGDVGGPGPPGASGEPGA--PGPPGKRGPSGHMGREGREGE--KGAKGEPGPDGPPGRT 1342 Query: 976 GYEGRQGPPGPPGPPGPPSFPGPHRQ--TISVPGPPGPPGPPGPPGTMG 1022 G G +GPPG GP G PGP + + PG GPPGP GP G G Sbjct: 1343 GPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPG 1391 Score = 510 bits (1313), Expect = e-144 Identities = 349/869 (40%), Positives = 417/869 (47%), Gaps = 134/869 (15%) Query: 244 SDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEE-- 301 SDG G G + + G+A P P P V +G + + E+ E+ Sbjct: 678 SDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGT--SGNRGLQGEKGEKGEDGF 735 Query: 302 ---QTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPG 358 + V G Q PG+ DG P G + G G++G PG G G+ G PG Sbjct: 736 PGFKGDVGLKGDQGKPGAPGPRGEDG----PEGPKGQAGQAGEEGPPGSAGEKGKLGVPG 791 Query: 359 SPCLPGPPG------LPCPVSPLGPAGPALQT----VPGPQGPPGPPGRDGTPG------ 402 P PG PG P P+ P+G G + +T + G +GPPG G G PG Sbjct: 792 LPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPG 851 Query: 403 ------RDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPG-VGERGPPGPQGPPG 455 +DG PG PGE G PG GP GFPG G G +G G PG G+RG G QG G Sbjct: 852 PKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTG 911 Query: 456 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 515 PPGP+ + G G++ L G RG PGPPGPPG GLPG GR G Sbjct: 912 PPGPAGV--------LGPQGKTGEVGPL-GERGPPGPPGPPGEQGLPGLEGREGAKGELG 962 Query: 516 P-------GPAGLPGVPGREGPPGFPGLPG------PPGPPGREGPPGRTGQKGSLGEAG 562 P GPAGL G PG +G PG PG G PPGP G G PG G G G G Sbjct: 963 PPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIG 1022 Query: 563 APGHKGSKGAPGPAGARGESGLAGAPGPAGP---PGPPGPPGPPGPGLPAGFDDMEGS-G 618 PG GS+G GPAG +G G G PGP G PGP GP GPPG P+G + +G G Sbjct: 1023 LPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVG 1082 Query: 619 GPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAG--- 675 P ++ G GPPG PG++G G PG PGA G G G PG G G +G+ G Sbjct: 1083 APGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVG 1142 Query: 676 ---PQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGR 731 P G +G G GEKG+ G G +G G PGP GP GP + +G+ +PG G+ Sbjct: 1143 VIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGP----TGSEGTP-GLPGGVGQ 1197 Query: 732 PGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRG 791 PG G G G G+ G G G PGPKG+ GE G P G A P +KG GE G +G Sbjct: 1198 PGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDS-GPSGAAGPPGKKGPPGEDGAKG 1256 Query: 792 PPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPP 851 GP G PG ++G PG PG G++G GEKG+PGD G PGPPG G PG P Sbjct: 1257 SVGPTGLPG---DLGPPGDPGVSGIDGSPGEKGDPGDV-------GGPGPPGASGEPGAP 1306 Query: 852 GTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGE 911 G P + GP G G +G G KGAKGE GP GPPG+ G Sbjct: 1307 GPP----------GKRGPSGHMGREGREGEKGAKGEPGPDGPPGR---------TGPMGA 1347 Query: 912 KGDRGDAGQKGERGEPGGGGFFG----SSLPGPPGPPGPRGYPGIPG---PKGES----I 960 +G G G +G RG PG G G GPPGP GP G PG+ G PKGE + Sbjct: 1348 RGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGL 1407 Query: 961 RGQPGPPGP------QGPPGI-GYEGRQGPPGPPGP------PGPPSFPGPHRQ------ 1001 G GPPG QG PG+ G G +G PGPPGP PGPP GP Q Sbjct: 1408 IGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGS 1467 Query: 1002 --TISVPGPPGPPGPPGPPGTMGASSGVR 1028 ++ G GP GPPGPPG G+R Sbjct: 1468 PGSMGPRGDTGPAGPPGPPGAPAELHGLR 1496 Score = 509 bits (1311), Expect = e-144 Identities = 420/1231 (34%), Positives = 510/1231 (41%), Gaps = 261/1231 (21%) Query: 12 RRRLLDVLAPLVLLLGVRAASAEPERISEEVGLLQ-LLGDPPPQQVTQTDDPDVGLAYVF 70 R L +LA L LL G +A +P + + +G+ G P P+ A+ Sbjct: 11 RAGLCLLLAALQLLPGTQA---DPVDVLKALGVQGGQAGVPEGPGFCPQRTPEGDRAFRI 67 Query: 71 GPDANSGQVARYHFPSLFF-RDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQ 129 G + G FP F +FSLL +R VL +I D A L G+ L Sbjct: 68 GQASTLGIPTWELFPEGHFPENFSLLITLRGQPANQSVLLSIYDERGARQL-GLALGPA- 125 Query: 130 DGHQDISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLA 189 + LL G ++ G+W +A+S+ G V L DCE Q L Sbjct: 126 -----LGLL------GDPFRPLPQQVNLTDGRWHRVAVSIDGEMVTLVADCEA-QPPVLG 173 Query: 190 RSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQ---------------VSPM 234 R + + AGL V F+G I EL + DPQ ++P Sbjct: 174 HGPRFISI---AGLTVLGTQDLGEKTFEGDIQELLISPDPQAAFQACERYLPDCDNLAPA 230 Query: 235 HCLDEEGDDSDGASGDSGSGLG-------------------------------DARELLR 263 + +G+ G G G + ++ + Sbjct: 231 ATVAPQGEPETPRPRRKGKGKGRKKGRGRKGKGRKKNKEIWTSSPPPDSAENQTSTDIPK 290 Query: 264 EETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWD 323 ET A P P P VT+ G ++T RS + + T + +L + + D Sbjct: 291 TETPAPNLPPTPTPLVVTSTVTTGLNATILERSLDPDSGTELGTLETKAAREDEE---GD 347 Query: 324 GSVRTPGGRVKE------------GGLKGQKGE-------------PGVPGPPGRAGPPG 358 S P R E G KG KGE PG PGP G GP G Sbjct: 348 DSTMGPDFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSG 407 Query: 359 SPCLPGPPGLPCPVSPLGPAG----PALQTVPGP-------------------------- 388 PGPPG P P GPAG P + + GP Sbjct: 408 P---PGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQA 464 Query: 389 -------------QGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQ------------- 422 +GPPGP G G PG G PG PG G+ G GPQ Sbjct: 465 QAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPG 524 Query: 423 -----------GFPGTPGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHD 464 G G PGD GPKGD+G G+ G+RG G G PGPPG Sbjct: 525 RVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERG 584 Query: 465 KLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGV---------------PGLPGEPGRFG 509 G L GPRG PGP G PGV PG PG PG+ G Sbjct: 585 AEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQG 644 Query: 510 VNSSD-VPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKG 568 + S +PGP GL G PG +GPPG PG+PG PG G G PG G G G G PG G Sbjct: 645 NHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAG 704 Query: 569 SKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSA 628 G PGP G +G SG G G G G G PG G G G+ GP R Sbjct: 705 PPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGP-----RGE 759 Query: 629 DGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGRE---GIAGPQGPKGDRGS 685 DGP+GP G G G+ G PG G KG++G G+PG+PG PG + G GP GP G++G Sbjct: 760 DGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGK 819 Query: 686 RGEKGDPGKDGV----------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGF- 734 G+ G PG +G GQPG G PGP G V QDG+ +PG +G PG Sbjct: 820 SGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDV----GQDGAP-GIPGEKGLPGLQ 874 Query: 735 --AGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSP-DGGALGPAQK-GAKGEPGFR 790 GFPGP GP G+ G G G PG +GE G G P G LGP K G G G R Sbjct: 875 GPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGER 934 Query: 791 GPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGP 850 GPPGP G PG +G G GR G G G G G+ G A G+RG PGP G PG PGP Sbjct: 935 GPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPA----GLRGFPGPKGGPGDPGP 990 Query: 851 PGT--------PVYDSNVFAESSRPGP------PGLPGNQGPPGP---KGAKGEVGPPGP 893 G PV + E GP PG G++GP GP KG++GE GPPGP Sbjct: 991 TGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGP 1050 Query: 894 PGQ--FPFDFLQL----EAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPR 947 G+ P L A GE+GD+GD G G +G G G G PG PG GP Sbjct: 1051 TGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGP--PGQPGIRGPA 1108 Query: 948 GYPGIPGPKG-ESIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPGPP---------SFP 996 G+PG PG G + RG PG G +G G+ G+ G GPPG G PGPP Sbjct: 1109 GHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSM 1168 Query: 997 GPHRQTISVPGPPGPPGPPGPPGTMGASSGV 1027 GPH PGP GP GP G GT G GV Sbjct: 1169 GPH----GAPGPRGPQGPTGSEGTPGLPGGV 1195 Score = 487 bits (1254), Expect = e-137 Identities = 331/805 (41%), Positives = 378/805 (46%), Gaps = 114/805 (14%) Query: 309 GAQTLPGSDSVST---WDGSVRTPGGRVKEG-----------GLKGQKGEPGVPGPPGRA 354 GA+ LPG +DG PG + + G G G++G G PGP G+A Sbjct: 536 GARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQA 595 Query: 355 GPPGSPCLPGPPGLPCPVSPLGPAG----PALQTVPGPQGPPGPPGRDGTPGRDGEPGDP 410 G PG L GP G P P G G P + GP G PGPPG+ G G G PG Sbjct: 596 GEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQ 655 Query: 411 GEDGKPGDTGPQGFPGTPGDVGPKGDKGDPG-------VGERGPPGPQGPPGPPGPSFRH 463 G G PG+ GP G PG PG G G G PG G +GPPG GPPG PGP Sbjct: 656 GLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVK 715 Query: 464 DKLTFIDMEGS----------GFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSS 513 ++G GF GD+ L+G +G PG PGP G G G G+ G Sbjct: 716 GTSGNRGLQGEKGEKGEDGFPGFKGDV-GLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGE 774 Query: 514 DVP----------GPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGA 563 + P G GLPG PGR GP G G PGP GP G +G G+TGQ G GE G Sbjct: 775 EGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGP 834 Query: 564 PGHKGSKGAPG------PAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGS 617 PG +G +G PG P G G+ G G PG G PG GPPG PGP P G +G Sbjct: 835 PGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGR 894 Query: 618 GG-PFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPG------FPGLPGR 670 G P G GPPG G+ G G G G GE G G PG PGL GR Sbjct: 895 PGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGR 954 Query: 671 EGIAG---PQGPKGDRGSRGEKGDPG-KDGVGQPG---LPGPPGPPGPV-VYVSEQDGSV 722 EG G P GP G G G +G PG K G G PG L G GPPGPV S + Sbjct: 955 EGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGP 1014 Query: 723 LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDG--GALGPAQ 780 L G G PG +G GP GP G GS+GERG PGP G+ G PG + P G GA GP+ Sbjct: 1015 LGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPL-GPLGPPGAAGPSG 1073 Query: 781 K----------GAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG---EPG 827 + G KG G +G GP G+PG +G G PG PG G G +G G + G Sbjct: 1074 EEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKG 1133 Query: 828 DASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE 887 D + G G+ GPPG G PGPPG + + GP G PG +GP GP G++G Sbjct: 1134 DDGVR-GFVGVIGPPGLQGLPGPPG----EKGEVGDVGSMGPHGAPGPRGPQGPTGSEGT 1188 Query: 888 VGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFG-------SSLPGP 940 G PG GQ GEKG+RGDAG G G PG G G S G Sbjct: 1189 PGLPGGVGQ---------PGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGA 1239 Query: 941 PGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPH 999 GPPG +G PG G KG G G PG GPPG G G G PG G PG PGP Sbjct: 1240 AGPPGKKGPPGEDGAKGSV--GPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGP- 1296 Query: 1000 RQTISVPGPPGPPGPPGPPGTMGAS 1024 PG G PG PGPPG G S Sbjct: 1297 ------PGASGEPGAPGPPGKRGPS 1315 Score = 342 bits (877), Expect = 1e-93 Identities = 243/623 (39%), Positives = 275/623 (44%), Gaps = 107/623 (17%) Query: 309 GAQTLPGSDSVSTWDGSVRTPGGRVKEG-----GLKGQKGEPGVPGPPGRAGPPGSPCLP 363 G Q LPG + G + PG KEG G G KG PG PGP G G G P Sbjct: 944 GEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPV 1003 Query: 364 GPPGLPCPVSPLGPAGP-ALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQ 422 G G P PLGPAG L G +GP GP G+ G+ G G PG G+DG PG GP Sbjct: 1004 GANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPL 1063 Query: 423 GFPGTPGDVGPKGDKGDPGV----------GERGPPG------PQGPPGPPGPSFRHDKL 466 G PG G G +GDKGD G G+ GPPG P G PGPPG + Sbjct: 1064 GPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRR 1123 Query: 467 TFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFG-------VNSSDVPGPA 519 + G G D G RGF G GPPG+ GLPG PG G + PGP Sbjct: 1124 GPPGLFGQK-GDD-----GVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPR 1177 Query: 520 G---------LPGVPGR------------------EGPPGFPGLPGPPG----------- 541 G PG+PG GPPG PG+PGP G Sbjct: 1178 GPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPS 1237 Query: 542 ----PPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPP 597 PPG++GPPG G KGS+G G PG G G PG +G G G G PG G PGPP Sbjct: 1238 GAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPP 1297 Query: 598 GP------PGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPG 651 G PGPPG P+G EG G A+ GP GPPG G G G PG G Sbjct: 1298 GASGEPGAPGPPGKRGPSGHMGREGREGE--KGAKGEPGPDGPPGRTGPMGARGPPGRVG 1355 Query: 652 AKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPG 710 +G G G G PGL G G GP GP G G G KGD G G G GL G GPPG Sbjct: 1356 PEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPG 1415 Query: 711 PVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFS 770 +Q +PG +G PG G PGP GP G+LG G G GP G+KG GS Sbjct: 1416 EAGEKGDQ-----GLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGS--- 1467 Query: 771 PDGGALGPAQKGAKGEPGFRGPPGPYGRP----GYKGEIGFPGRPGRPGMNGLKGEKGEP 826 P G +G+ G GPPGP G P G + F P GL E+ Sbjct: 1468 -------PGSMGPRGDTGPAGPPGPPGAPAELHGLRRRRRFVPVPLPVVEGGL--EEVLA 1518 Query: 827 GDASLGFGMRGMPGPPGPPGPPG 849 SL + + PPG PG Sbjct: 1519 SLTSLSLELEQLRRPPGTAERPG 1541 Score = 266 bits (679), Expect = 1e-70 Identities = 178/455 (39%), Positives = 199/455 (43%), Gaps = 64/455 (14%) Query: 239 EEGDDSD-------GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSST 291 EEGD D G+ GD G + +R G P PP G Sbjct: 1074 EEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKG 1133 Query: 292 EDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRT------PGGRVKEG--------G 337 +D V + G Q LPG G V + PG R +G G Sbjct: 1134 DDGVRGFVG---VIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPG 1190 Query: 338 LKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGR 397 L G G+PG G G G G P PG PG+P P +G G + GP G GPPG+ Sbjct: 1191 LPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDS-----GPSGAAGPPGK 1245 Query: 398 DGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPG-VGERGPPGPQGPPGP 456 G PG DG G G G PGD GP G PG G G G+KGDPG VG GPPG G PG Sbjct: 1246 KGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGA 1305 Query: 457 PGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPG---LPGEPGRFGVNSS 513 PGP + + EG E +G +G PGP GPPG G G PGR G Sbjct: 1306 PGPPGKRGPSGHMGREGR------EGEKGAKGEPGPDGPPGRTGPMGARGPPGRVG---- 1355 Query: 514 DVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAP 573 P GL G+PG G PG G PG GPPG GP G G KG G G GH G G Sbjct: 1356 ----PEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLI 1411 Query: 574 GPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQG 633 GP G GE G G PG GPPGP G PGPPGP + G P GP G Sbjct: 1412 GPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGP--------IGSLGHP---------GPPG 1454 Query: 634 PPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLP 668 G G KG G PG G +G+ G G PG PG P Sbjct: 1455 VAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAP 1489 Score = 77.4 bits (189), Expect = 8e-14 Identities = 92/292 (31%), Positives = 112/292 (38%), Gaps = 47/292 (16%) Query: 769 FSPDGGALGPAQKGA-KGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEK---- 823 + PD L PA A +GEP P P + KG GR G+ G K K Sbjct: 220 YLPDCDNLAPAATVAPQGEPE---TPRPRRKGKGKGRKKGRGRKGK----GRKKNKEIWT 272 Query: 824 -GEPGDASLGFGMRGMPGP--PGPPGPPGPPGTPVYDSNVFAES------SRPGPPGLPG 874 P D++ +P P P PP P TP+ ++ R P Sbjct: 273 SSPPPDSAENQTSTDIPKTETPAPNLPPTP--TPLVVTSTVTTGLNATILERSLDPDSGT 330 Query: 875 NQGPPGPKGAK----GEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGG 930 G K A+ G+ GP DF E + + AG+KG +GEP Sbjct: 331 ELGTLETKAAREDEEGDDSTMGP------DFRAAEYPSRTQFQIFPGAGEKGAKGEPAVI 384 Query: 931 GFFGSSLPGPPGPPGPRGYPGIPGPKGE-SIRGQPGPPGPQGPPGI-GYEGRQGPPGPP- 987 G GPPG PGP+G G GP G G PGPPGP G PGI G +G +GPPG Sbjct: 385 EK-GQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVI 443 Query: 988 ---------GPPGPP-SFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRL 1029 GPP SF Q + GPPGP G G V L Sbjct: 444 MMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGL 495 >gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo sapiens] Length = 1424 Score = 512 bits (1318), Expect = e-144 Identities = 357/880 (40%), Positives = 410/880 (46%), Gaps = 160/880 (18%) Query: 246 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 305 G GD G LR + G +P P V P G E + S E +Q Sbjct: 551 GVPGDPG---------LRGQPGRKGLDGIPGTPGVKGLP---GPKGELALSGEKGDQGPP 598 Query: 306 ASLGAQTLPGSDSVSTWDGSVRTPG-GRVKEGGLKGQKGEPGVPGPPGRAGPPG----SP 360 G+ PG G PG G E GL+G +G PG PGPPG AGP G S Sbjct: 599 GDPGSPGSPGPA------GPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652 Query: 361 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGR------DGTPGRDGEPGDPGED- 413 +PGPPG P GP G PGPQGPPG PG G PG DGEPG PG Sbjct: 653 PVPGPPGPP------GPPGH-----PGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF 701 Query: 414 -GKPGDTGPQGFPGT---------------PGDVGPKGDKGDPGVGERGPPGPQGPPGPP 457 G PG G QGFPGT PG G G KG+P V G PG G PG Sbjct: 702 PGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGER 761 Query: 458 GPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPG 517 G S H ++ + G E L GPRG PG PGPPG G PG + +PG Sbjct: 762 GNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPG 821 Query: 518 PAGLPGVPGREG---PPGFPGLPG--PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA 572 GL G GR G P G PG+PG G PG G PG G +G +G G G+ G+ G Sbjct: 822 LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGI 881 Query: 573 PGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGLPAGFDDMEGSGGPFWSTARSA 628 GP G G G+ G PG GPPGPPG PG PG PG+P G G+ G A+ Sbjct: 882 LGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIP-GVKGQRGTPG-----AKGE 935 Query: 629 DGPQGPPG------LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGD 682 G +G PG + G KG+PG+ G G GE G GVPG PGL G +G+ GP GP G Sbjct: 936 QGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGP 995 Query: 683 RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGF---- 737 RG G G+PG+ G+ G PG G G PG S+ L PG GRPG G Sbjct: 996 RGDLGSTGNPGEPGLRGIPGSMGNMGMPG-----SKGKRGTLGFPGRAGRPGLPGIHGLQ 1050 Query: 738 -------------PGPAGPKGN------LGSKGERGSPGPKGE------KGEPGSIFSPD 772 PGP GP G+ +G KGE G PGP G +G PGS SP Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110 Query: 773 -GGALGP-------AQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG 824 G GP KG G PG RGPPG G PG G +G G GR G+ G GEKG Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170 Query: 825 EPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR-----------PGPPGLP 873 E G G RG PG G G G PG P A PGPPGLP Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230 Query: 874 G--------NQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERG 925 G N+GPPG +G+ G GPPGPPG + + G KGD+G G G +G Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPG----------SHVIGIKGDKGSMGHPGPKG 1280 Query: 926 EPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE-SIRGQPGPPGPQGPPGIGYEGRQGPP 984 PG G G PPG G G PG+PGP+G+ +G PG G +G PG + G GPP Sbjct: 1281 PPGTAGDMG-----PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG--FLGSIGPP 1333 Query: 985 GPPGPPGPPSFPGPHR--QTISVPGPPGPPGPPGPPGTMG 1022 GP GP GPP G + IS+PG PGPPG PG PG G Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373 Score = 480 bits (1235), Expect = e-135 Identities = 351/939 (37%), Positives = 415/939 (44%), Gaps = 186/939 (19%) Query: 243 DSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQ 302 D+ GD G+ R G + P +P P + P L G + + E Sbjct: 348 DTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERG 407 Query: 303 TTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCL 362 A PGS + G +PG G + +KG PG G PG G PG P + Sbjct: 408 RP--GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGV 465 Query: 363 PGP---PGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT 419 GP PGL C P P P L +PG G G PGR G G G PG PG G PG Sbjct: 466 DGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGF- 524 Query: 420 GPQGFPGTPGDVGPKGDK-------------GDPGV-GERGPPGPQGPPGPPGPSFRHDK 465 GFPG GD G KG+K GDPG+ G+ G G G PG PG Sbjct: 525 --PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG------- 575 Query: 466 LTFIDMEG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRF---GVNSSDVPGPAGL 521 ++G G G+L AL G +G GPPG PG PG PG G G PG G Sbjct: 576 -----VKGLPGPKGEL-ALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGT 629 Query: 522 PGVPGREGPPG-------------FPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKG 568 GVPG GPPG PG PGPPGPPG GP G G GSLG+ G PG G Sbjct: 630 QGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPG 689 Query: 569 SKGA--------PGPAGARGESGLAGAPGPAGPPGPPGPPGPPG-PGLPAGFDDME---- 615 G PGP G +G+ G G G G PG G PG PG PGLP + Sbjct: 690 PDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMP 749 Query: 616 -GSGGPFWSTARSADGPQGP---PGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGR- 670 G G P + R G G PGLPGL G PG GL G +G+ G G PG G PGR Sbjct: 750 GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809 Query: 671 ----------EGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQ-- 718 G+ G +G +G RG G KGDPG G+ + G PG G PG + E Sbjct: 810 IEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGP 869 Query: 719 --------DGSVLSVPGPEGRPGFAGFP---GPAGPKGNLGS------------KGERGS 755 + +L PG +G G GFP GP GP GN G+ KG+RG+ Sbjct: 870 LGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929 Query: 756 PGPKGEKGEPGSIFSPD--------------GGALGPAQKGAKGEP------GFRGPPGP 795 PG KGE+G+ G+ + G A P +KG +G P G +G PGP Sbjct: 930 PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989 Query: 796 YGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPG-------DASLGF-GMRGMPGPPGPPGP 847 G PG +G++G G PG PG+ G+ G G G +LGF G G PG PG G Sbjct: 990 AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049 Query: 848 PGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQF------PFDF 901 G G P Y +E +RPGPPG G+ G PG G KGE+G PGPPG Sbjct: 1050 QGDKGEPGY-----SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPG 1104 Query: 902 LQLEAEMKGEKGDRGDAGQK---------GERGEPGGGGFFGS-------------SLPG 939 + G+ G GD G K G RG PG GF GS +PG Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG 1164 Query: 940 PPG----------PPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-IGYEGRQGPPGPPG 988 P G PPGPRG PG G KG+ RG PG PG G G +G G +GP G G Sbjct: 1165 PAGEKGETGLLRAPPGPRGNPGAQGAKGD--RGAPGFPGLPGRKGAMGDAGPRGPTGIEG 1222 Query: 989 PPGPPSFPGP-------HRQTISVPGPPGPPGPPGPPGT 1020 PGPP PG +R G PG PGPPGPPG+ Sbjct: 1223 FPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGS 1261 Score = 470 bits (1209), Expect = e-132 Identities = 340/890 (38%), Positives = 403/890 (45%), Gaps = 195/890 (21%) Query: 309 GAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSPCLPGP- 365 G + LPG + G G + G GL G G PG+PG PG GP G +PG Sbjct: 67 GPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCS 126 Query: 366 --------PGLPCPVSPLG-PAGPALQTVPGPQGPP-----------GPPGRDGTPGRDG 405 PGLP LG P P + G +G P G PG G PG G Sbjct: 127 GSKGEQGFPGLP---GTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQG 183 Query: 406 EPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPG---VGERGPPGPQGPPGPPGPSFR 462 PG PG G G GP GF G PG +GP+G KG G +G +G G +G GPPGP Sbjct: 184 LPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGP--- 240 Query: 463 HDKLTFIDMEGSGFGGDLEALRGPRGF---PGPPGP--------------PGVPGLPGEP 505 + + G DL+ +G +G PGPPGP PG PGL G+P Sbjct: 241 -PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKP 299 Query: 506 GRFGV----NSSDVPGPAGLPGVPGRE---------GPPGF---------------PGLP 537 G+ GV S V G G PG+ G + GPPGF G P Sbjct: 300 GKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTP 359 Query: 538 GPPGP-----------------------PGREGPPGRTGQKGSLGEAGAPGHKGSKGAPG 574 GPPGP PG G PG G KGS GE G PG K + G PG Sbjct: 360 GPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGTPG 418 Query: 575 PAGARGESGLAGAPGPAGPP-------GPPGPPGPPG----PGLPAGFDDMEGSGGPFWS 623 G G GL G+PGP GPP GPPG G PG PG+P G D +G G + Sbjct: 419 SPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIP-GVDGPKGEPGLLCT 477 Query: 624 TARSADGPQGPPGLPGLKGDPGVP------GLPGAKGEVGADGVPGFPGLPGREGIAGPQ 677 GP G PGLPGL G G+P GL G+ G G G+PGFPG PG +G G + Sbjct: 478 QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK 537 Query: 678 GPK-------------GDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVL 723 G K GD G RG+ G G DG+ G PG+ G PGP G + E+ Sbjct: 538 GEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ-- 595 Query: 724 SVPGPEGRPGFAGFPGPAGPKGN-----------LGSKGERGSPGPKGEKGEPG--SIFS 770 GP G PG G PGPAGP G G++G G+PGP GE G G S+ + Sbjct: 596 ---GPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652 Query: 771 PDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGL--------KGE 822 P G GP G G PG +GPPG G G G+ G PG G PG+ G+ KG+ Sbjct: 653 PVPGPPGP--PGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGD 710 Query: 823 KGEPG-DASLG----FGMRGMPGPPGPPGP--------PGPPGTPVY-----DSNVFAES 864 +G PG SLG G G+PG PG PG PG PGTP + +S E Sbjct: 711 QGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEI 770 Query: 865 SRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAE--------MKGEKGDRG 916 PG PGLPG G G G +G+ G PGPPG+ +E + G KG +G Sbjct: 771 GLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQG 830 Query: 917 DAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-- 974 G+ G +G+PG G S PG G PG G+ G GP G+ RG PG PG GPPG Sbjct: 831 RRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ--RGYPGNPGILGPPGED 888 Query: 975 --IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1022 IG G G GPPGPPG P PG R + +PG G G PG G G Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGTPG-QRGSPGIPGVKGQRGTPGAKGEQG 937 Score = 464 bits (1193), Expect = e-130 Identities = 352/942 (37%), Positives = 404/942 (42%), Gaps = 223/942 (23%) Query: 267 GAALKPRLPAPPPVTTP-PLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGS 325 G + P LP P T P L G S+ E+ +LG +PG+ G Sbjct: 100 GFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLP-GTLGYPGIPGAA------GL 152 Query: 326 VRTPGGRVKEGGLK-GQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP------------- 371 G KE ++ KG+PG+PG PG G PG P PGP G P P Sbjct: 153 KGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPR 212 Query: 372 ----------------------VSPLGPAGPALQTVPGPQ---------------GPPGP 394 P GP G + T+ GP G PGP Sbjct: 213 GPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGP 272 Query: 395 PGRDGTPGRD-----GEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV----GER 445 PG G PG G PGDPG GKPG G GFPG+ G KG++G PG+ G + Sbjct: 273 PGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEG---VKGNRGFPGLMGEDGIK 329 Query: 446 GPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEP 505 G G GPPG GP+ +D T+ + G G GPRG GP GP G PG+PG P Sbjct: 330 GQKGDIGPPGFRGPTEYYD--TYQEKGDEGTPGP----PGPRGARGPQGPSGPPGVPGSP 383 Query: 506 GRFGVNSSDVPGPAGL-----------------PGVPGREGPPGFPGLPGPPGPPG---- 544 G PG GL PG PG G PG PG PGPPGPPG Sbjct: 384 GSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVF 443 Query: 545 REGPPGRTGQKGSLGEAGAPGHKGSKGAPGPA-----------------GARGESGLAGA 587 R+GPPG G G LG G PG G KG PG G G G+ G Sbjct: 444 RKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGR 503 Query: 588 PGPAGPPGPPGPPGPPG-PGLPAGFDDMEGSGGPFWSTARSA--DGPQGPPGLPGLKGDP 644 G AG G PG PG G PG P GF +G G + +G G PG PGL+G P Sbjct: 504 QGAAGLKGSPGSPGNTGLPGFP-GFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQP 562 Query: 645 G------------VPGLPGAKGEV------GADGVPGFPGLPGREGIAGPQGPKGDRGSR 686 G V GLPG KGE+ G G PG PG PG G AGP GP G Sbjct: 563 GRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG----Y 618 Query: 687 GEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKG 745 G +G+PG G G PG PGPPG GP +S VPGP G PG G PGP GP G Sbjct: 619 GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST----PVPGPPGPPGPPGHPGPQGPPG 674 Query: 746 ---NLGSKGERGSPGPKGEKGEPGSIFSPDGGALG----PAQKGAKGEPGFRGPPGPYGR 798 +LG G+ G PGP GE G PG F G G P KG+ G PG G PG G+ Sbjct: 675 IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGK 734 Query: 799 PGY---KGE--IGFPGRPGRPGMNGLKGEKGEPGDASLGF--------------GMRGMP 839 PG KGE + PG PG PG G +G GE G+ L G RG P Sbjct: 735 PGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDP 794 Query: 840 GPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPF 899 G PGPPG GPPG + E R G GLPG G G +G +G+ GP G PG Sbjct: 795 GQPGPPGEQGPPGRCI-------EGPR-GAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGL 846 Query: 900 DFLQLEAEM--KGEKGDRGDAGQKGERGEPGGGGFFGS-------------------SLP 938 D E G G +G+ G G+RG PG G G P Sbjct: 847 DRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPP 906 Query: 939 GPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI----------------GYEGRQG 982 G PG PG RG PGIPG KG+ RG PG G QG G G +G G Sbjct: 907 GNPGTPGQRGSPGIPGVKGQ--RGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAG 964 Query: 983 PPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGAS 1024 PG G G P PG + G PGP GPPGP G +G++ Sbjct: 965 NPGEKGNRGVPGMPGLK----GLKGLPGPAGPPGPRGDLGST 1002 Score = 458 bits (1178), Expect = e-128 Identities = 322/776 (41%), Positives = 365/776 (47%), Gaps = 129/776 (16%) Query: 337 GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPG 396 G KG+KGE G PGPPG G G GP GLP P P G G +PG G G G Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKG---FTGPEGLPGPQGPKGFPG-----LPGLTGSKGVRG 94 Query: 397 RDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPG 455 G PG G PG PG PG+TGP G G PG G KG++G PG+ G G PG G G Sbjct: 95 ISGLPGFSGSPGLPGT---PGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAG 151 Query: 456 PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 515 G K I+++ G G L GP+G PGPPG PG G PG PG FG + Sbjct: 152 LKGQKGAPAKEEDIELDAKGDPG-LPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMG 210 Query: 516 P-GPAGLPG--VPGREGPPGFPGLPGPPGPPGR-----EGPPGRT---GQKGSLGEAGAP 564 P GP G G V G +G G GL GPPGPPG GP RT G+KG G G P Sbjct: 211 PRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEP 270 Query: 565 GHKGSKGAPGPA-----GARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGG 619 G G G PG + GA G+ GL G PG G PG PG G G GF + G G Sbjct: 271 GPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN---RGFPGLMGEDG 327 Query: 620 PFWSTARSADGPQGPPGLPGL---------KGDPGVPGLPG---AKGEVGADGVPGFPGL 667 + G GPPG G KGD G PG PG A+G G G PG PG Sbjct: 328 -----IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGS 382 Query: 668 PG--REGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSV 725 PG R G+ G G G +GS+GE+G PGKD +G PG PG G PG + Sbjct: 383 PGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPG-----------LPGS 431 Query: 726 PGPEGRPGFAGF-PGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFS-------PDGGALG 777 PGP G PG F GP G G G G G PG G KGEPG + + P G Sbjct: 432 PGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGL 491 Query: 778 PAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNG---LKGEKGE--------- 825 P G KG PG +G G G PG G G PG PG PG G LKGEKGE Sbjct: 492 PGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVG 551 Query: 826 -PGDASLGF-----GMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPP 879 PGD L G+ G+PG PG G PGP G + + E GPPG PG+ G P Sbjct: 552 VPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKG----ELALSGEKGDQGPPGDPGSPGSP 607 Query: 880 GPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPG 939 GP GP GPPG P Q E ++G +G G G GE G P G + +PG Sbjct: 608 GP------AGPAGPPGYGP----QGEPGLQGTQGVPGAPGPPGEAG-PRGELSVSTPVPG 656 Query: 940 PPGPPGPRGYPGIPGPKGESIR----GQPGPPGPQGPPGIGYEGRQGPPGP--------- 986 PPGPPGP G+PG GP G G PG PGP G PGI G GPPGP Sbjct: 657 PPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGT 716 Query: 987 ------------PGPPGPPSFPGPHRQ-TISVPGPPGPPGPPGPPGTMGASSGVRL 1029 PG PG P PG + +++PG PG PG PG G G + L Sbjct: 717 KGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGL 772 Score = 404 bits (1038), Expect = e-112 Identities = 289/717 (40%), Positives = 332/717 (46%), Gaps = 161/717 (22%) Query: 436 DKG----DPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPG 491 DKG D GE+G G GPPG PG GF GP G PG Sbjct: 35 DKGQCFCDGAKGEKGEKGFPGPPGSPGQK--------------GF-------TGPEGLPG 73 Query: 492 PPGPPGVPGLPGEPGRFGVNS-SDVPG---PAGLPGVPGREGPPGFPGLPGPPGPPGREG 547 P GP G PGLPG G GV S +PG GLPG PG GP G G+PG G G +G Sbjct: 74 PQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQG 133 Query: 548 PPGRTGQKGSLGEAGAPGHKGSKGAPGPA-----GARGESGLAGAPGPAGPPGPPGPPGP 602 PG G G G GA G KG KGAP A+G+ GL GAPGP G PGPPG PGP Sbjct: 134 FPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGP 193 Query: 603 PGPGLPAGFDDMEGSGGPFWSTARSAD---------------GPQGPPG----------- 636 GP P GF G+ GP + GP GPPG Sbjct: 194 VGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDN 253 Query: 637 ---LPGLKGDPGVPGLPGAKG-----------EVGADGVPGFPGLPGREGIAGPQGPKGD 682 L G KGD G G PG G E GA G PG G PG++G+ G G +G Sbjct: 254 RTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGV 313 Query: 683 RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSE-QDGSVLSVPGPEGRPGFAGFPGP 740 +G+RG G G+DG+ GQ G GPPG GP Y Q+ PGP G G G GP Sbjct: 314 KGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGP 373 Query: 741 AGPKGNLGSKGE-----RGSPGPKGEKGEPGSIFSPDGGALG----PAQKGAKGEPGFRG 791 +GP G GS G RG+PG G KG G P A+G P G+ G PG G Sbjct: 374 SGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPG 433 Query: 792 PPGPYG----RPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLG--------------- 832 PPGP G R G G+ G PG G PG+ G+ G KGEPG Sbjct: 434 PPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493 Query: 833 -FGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE---- 887 G++G+PG G G G PG+P + PG PG PG QG PG KG KGE Sbjct: 494 LHGVKGIPGRQGAAGLKGSPGSP-------GNTGLPGFPGFPGAQGDPGLKGEKGETLQP 546 Query: 888 ---VGPPGPPG------QFPFDFLQLEAEMKGEKGDRGD---AGQKGERGEPGGGGFFGS 935 VG PG PG + D + +KG G +G+ +G+KG++G PG G GS Sbjct: 547 EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606 Query: 936 SLPGPPGPPGPRGY--------------PGIPGPKGES-IRGQ-------PGPPGPQGPP 973 PGP GP GP GY PG PGP GE+ RG+ PGPPGP GPP Sbjct: 607 --PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664 Query: 974 GIGYEGRQGPPGPP---GPPGPPSFPGPHRQT----ISVPGPPGPPGPPGPPGTMGA 1023 G + G QGPPG P G G P PGP + I PGPPGP G G PGT G+ Sbjct: 665 G--HPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719 Score = 398 bits (1022), Expect = e-110 Identities = 276/703 (39%), Positives = 313/703 (44%), Gaps = 142/703 (20%) Query: 272 PRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGG 331 P P PP PP G E R GAQ LPG + + G G Sbjct: 794 PGQPGPPGEQGPP---GRCIEGPR-------------GAQGLPGLNGLKGQQGRRGKTGP 837 Query: 332 RVKEG-------GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQT 384 + G G G+ G PG+PG G GP G PG PG+ P G G + Sbjct: 838 KGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIG--MMG 895 Query: 385 VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPK------GDKG 438 PG GPPGPPG GTPG+ G PG PG G+ G G +G G G+ GP GDKG Sbjct: 896 FPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKG 955 Query: 439 DPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP----- 492 +PG+ G G PG +G G PG G G L+ L GP G PGP Sbjct: 956 EPGLKGFAGNPGEKGNRGVPGMP--------------GLKG-LKGLPGPAGPPGPRGDLG 1000 Query: 493 ----PGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGL------------ 536 PG PG+ G+PG G G+ S G G G PGR G PG PG+ Sbjct: 1001 STGNPGEPGLRGIPGSMGNMGMPGSK--GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGY 1058 Query: 537 -----PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPA 591 PGPPGP G G PG G+KG +G+ G PGH G G G G+ G GL G PGP Sbjct: 1059 SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPH 1118 Query: 592 GPPG---------PPGPPGPPG-PGLPAGFDDMEGSGGPFWSTA-RSADGPQGPPGLPG- 639 G G PPG GPPG PG P GS GP + DG GP G G Sbjct: 1119 GDLGFKGIKGLLGPPGIRGPPGLPGFP-------GSPGPMGIRGDQGRDGIPGPAGEKGE 1171 Query: 640 ---LKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG 696 L+ PG G PGA+G G G PGFPGLPGR+G G GP+G G G G PG G Sbjct: 1172 TGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPG 1231 Query: 697 V---------------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPA 741 G PG PGPPGPPG V + D + PGP+G PG AG Sbjct: 1232 AIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG---DM 1288 Query: 742 GPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGY 801 GP G LG+ G G PGP+G+ G G P KG KG PGF G GP G G Sbjct: 1289 GPPGRLGAPGTPGLPGPRGDPGFQGF----------PGVKGEKGNPGFLGSIGPPGPIGP 1338 Query: 802 KGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVF 861 KG G G PG + L G G PG GM+G PGPPGPPG GP G Sbjct: 1339 KGPPGVRGDPGTLKIISLPGSPGPPGTPGEP-GMQGEPGPPGPPGNLGPCG--------- 1388 Query: 862 AESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQL 904 P G PG G PG G GE G G G+ F QL Sbjct: 1389 -------PRGKPGKDGKPGTPGPAGEKGNKGSKGEPESLFHQL 1424 Score = 327 bits (839), Expect = 4e-89 Identities = 229/609 (37%), Positives = 272/609 (44%), Gaps = 112/609 (18%) Query: 241 GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 300 G D G G++GS + E G + P P + PP G + Sbjct: 845 GLDRSGFPGETGSPGIPGHQ---GEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIG 901 Query: 301 EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGG-----------LKGQKGEPGV-- 347 + G GS + G TPG + ++G + G KGEPG+ Sbjct: 902 PPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKG 961 Query: 348 ----PGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG----------PALQTVPGPQGPPG 393 PG G G PG P L G GLP P P GP G P L+ +PG G G Sbjct: 962 FAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMG 1021 Query: 394 PPGRDGT------PGRDGEPGDPGEDG--------------KPGDTGPQGFPGTPGDVGP 433 PG G PGR G PG PG G +PG GP G PG PGD+G Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGK 1081 Query: 434 KGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP 492 KG+ G PG G GP GP+G PG PG K G GDL +G +G GP Sbjct: 1082 KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK--------PGPHGDL-GFKGIKGLLGP 1132 Query: 493 PG---PPGVPGLPGEPGRFGVNSSD----VPGPAGLPGVPGR----EGPPGFPGLPGPPG 541 PG PPG+PG PG PG G+ +PGPAG G G GP G PG G G Sbjct: 1133 PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKG 1192 Query: 542 PPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARG-----ESGLAGAPGPAGPPGP 596 G G PG G+KG++G+AG G G +G PGP G G ++G G PG G PG Sbjct: 1193 DRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGA 1252 Query: 597 PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGL------PGLKGDPGVPGLP 650 PGPPGPPG + D G P GP+GPPG PG G PG PGLP Sbjct: 1253 PGPPGPPGSHVIGIKGDKGSMGHP---------GPKGPPGTAGDMGPPGRLGAPGTPGLP 1303 Query: 651 GAKGEVGADGVPGFPGL---PGREGIAGPQGPKGDRGSRGEKGDPGK-DGVGQPGLPGPP 706 G +G+ G G PG G PG G GP GP G +G G +GDPG + PG PGPP Sbjct: 1304 GPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPP 1363 Query: 707 GPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPG---PAGPKGNLGSKGERGSPGPKGEKG 763 G PG PG +G PG G PG P GP+G G G+ G+PGP GEKG Sbjct: 1364 GTPGE--------------PGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409 Query: 764 EPGSIFSPD 772 GS P+ Sbjct: 1410 NKGSKGEPE 1418 Score = 276 bits (706), Expect = 1e-73 Identities = 201/508 (39%), Positives = 230/508 (45%), Gaps = 106/508 (20%) Query: 567 KGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTAR 626 KG G G +GE G G PG G G GP G PGP P GF + G G Sbjct: 36 KGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTG------- 88 Query: 627 SADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPG---------FPGLP---GREGIA 674 + G +G GLPG G PG+PG PG G G GVPG FPGLP G GI Sbjct: 89 -SKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIP 147 Query: 675 GPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGF 734 G G KG +G+ ++ D D G PGLPG PGP+G PG Sbjct: 148 GAAGLKGQKGAPAKEEDIELDAKGDPGLPG--------------------APGPQGLPGP 187 Query: 735 AGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPG 794 GFPGP GP G G G G+ GP+G KG G +G KG +G G GPPG Sbjct: 188 PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGE------RVIG--HKGERGVKGLTGPPG 239 Query: 795 PYGR--------------PGYKGEIGFPGRPGRPGMNGLKGE-----KGEPGDASLGFGM 835 P G G KG+ G G PG PG +GL GE KG PGD G+ Sbjct: 240 PPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDP----GL 295 Query: 836 RGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPG 895 +G PG G PG PG G G G PG G G KG KG++GPPG G Sbjct: 296 QGKPGKDGVPGFPGSEGVK-------------GNRGFPGLMGEDGIKGQKGDIGPPGFRG 342 Query: 896 QFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGP--PGPRGYPGIP 953 P ++ E KG++G G G +G RG G G G +PG PG PG RG PG P Sbjct: 343 --PTEYYDTYQE-KGDEGTPGPPGPRGARGPQGPSGPPG--VPGSPGSSRPGLRGAPGWP 397 Query: 954 GPKG-ESIRGQPGPP--GPQGPPGI-GYEGRQGPPGPPGPPGPPSF----PGPHRQTISV 1005 G KG + RG+PG G G PG G G G PGPPGPPG F PG H Sbjct: 398 GLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH------ 451 Query: 1006 PGPPGPPGPPGPPGTMGASSGVRLWATR 1033 G PG G PG PG G L T+ Sbjct: 452 -GLPGYLGSPGIPGVDGPKGEPGLLCTQ 478 Score = 168 bits (426), Expect = 3e-41 Identities = 118/312 (37%), Positives = 134/312 (42%), Gaps = 72/312 (23%) Query: 766 GSIFSPDGGALGPAQKGAKGEPGFRGPP---------GPYGRPGYKGEIGFPGRPGRPGM 816 G + G KG KGE GF GPP GP G PG +G GFPG PG G Sbjct: 30 GCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGS 89 Query: 817 NGLKGEKGEPGDASLGFGMRGMPGPPGPPGP------------------PGPPGT----- 853 G++G G PG + G G+PG PG GP PG PGT Sbjct: 90 KGVRGISGLPGFS----GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145 Query: 854 -------------PVYDSNVFAES-SRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPF 899 P + ++ ++ PG PG PG QG PGP G G VGPPGPPG F F Sbjct: 146 IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205 Query: 900 DFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPP--------GPRGYPG 951 KG G+R G KGERG G L GPPGPP GP Sbjct: 206 PGAMGPRGPKGHMGER-VIGHKGERGVKG--------LTGPPGPPGTVIVTLTGPDNRTD 256 Query: 952 IPGPKGE-SIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPG 1010 + G KG+ G+PGPPGP G PG Y +G PG PG G P G PG G Sbjct: 257 LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDG----VPGFPGSEG 312 Query: 1011 PPGPPGPPGTMG 1022 G G PG MG Sbjct: 313 VKGNRGFPGLMG 324 >gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo sapiens] Length = 1494 Score = 512 bits (1318), Expect = e-144 Identities = 357/880 (40%), Positives = 410/880 (46%), Gaps = 160/880 (18%) Query: 246 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 305 G GD G LR + G +P P V P G E + S E +Q Sbjct: 551 GVPGDPG---------LRGQPGRKGLDGIPGTPGVKGLP---GPKGELALSGEKGDQGPP 598 Query: 306 ASLGAQTLPGSDSVSTWDGSVRTPG-GRVKEGGLKGQKGEPGVPGPPGRAGPPG----SP 360 G+ PG G PG G E GL+G +G PG PGPPG AGP G S Sbjct: 599 GDPGSPGSPGPA------GPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652 Query: 361 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGR------DGTPGRDGEPGDPGED- 413 +PGPPG P GP G PGPQGPPG PG G PG DGEPG PG Sbjct: 653 PVPGPPGPP------GPPGH-----PGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF 701 Query: 414 -GKPGDTGPQGFPGT---------------PGDVGPKGDKGDPGVGERGPPGPQGPPGPP 457 G PG G QGFPGT PG G G KG+P V G PG G PG Sbjct: 702 PGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGER 761 Query: 458 GPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPG 517 G S H ++ + G E L GPRG PG PGPPG G PG + +PG Sbjct: 762 GNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPG 821 Query: 518 PAGLPGVPGREG---PPGFPGLPG--PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA 572 GL G GR G P G PG+PG G PG G PG G +G +G G G+ G+ G Sbjct: 822 LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGI 881 Query: 573 PGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGLPAGFDDMEGSGGPFWSTARSA 628 GP G G G+ G PG GPPGPPG PG PG PG+P G G+ G A+ Sbjct: 882 LGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIP-GVKGQRGTPG-----AKGE 935 Query: 629 DGPQGPPG------LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGD 682 G +G PG + G KG+PG+ G G GE G GVPG PGL G +G+ GP GP G Sbjct: 936 QGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGP 995 Query: 683 RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGF---- 737 RG G G+PG+ G+ G PG G G PG S+ L PG GRPG G Sbjct: 996 RGDLGSTGNPGEPGLRGIPGSMGNMGMPG-----SKGKRGTLGFPGRAGRPGLPGIHGLQ 1050 Query: 738 -------------PGPAGPKGN------LGSKGERGSPGPKGE------KGEPGSIFSPD 772 PGP GP G+ +G KGE G PGP G +G PGS SP Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110 Query: 773 -GGALGP-------AQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG 824 G GP KG G PG RGPPG G PG G +G G GR G+ G GEKG Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170 Query: 825 EPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR-----------PGPPGLP 873 E G G RG PG G G G PG P A PGPPGLP Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230 Query: 874 G--------NQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERG 925 G N+GPPG +G+ G GPPGPPG + + G KGD+G G G +G Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPG----------SHVIGIKGDKGSMGHPGPKG 1280 Query: 926 EPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE-SIRGQPGPPGPQGPPGIGYEGRQGPP 984 PG G G PPG G G PG+PGP+G+ +G PG G +G PG + G GPP Sbjct: 1281 PPGTAGDMG-----PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG--FLGSIGPP 1333 Query: 985 GPPGPPGPPSFPGPHR--QTISVPGPPGPPGPPGPPGTMG 1022 GP GP GPP G + IS+PG PGPPG PG PG G Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373 Score = 480 bits (1235), Expect = e-135 Identities = 351/939 (37%), Positives = 415/939 (44%), Gaps = 186/939 (19%) Query: 243 DSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQ 302 D+ GD G+ R G + P +P P + P L G + + E Sbjct: 348 DTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERG 407 Query: 303 TTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCL 362 A PGS + G +PG G + +KG PG G PG G PG P + Sbjct: 408 RP--GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGV 465 Query: 363 PGP---PGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT 419 GP PGL C P P P L +PG G G PGR G G G PG PG G PG Sbjct: 466 DGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGF- 524 Query: 420 GPQGFPGTPGDVGPKGDK-------------GDPGV-GERGPPGPQGPPGPPGPSFRHDK 465 GFPG GD G KG+K GDPG+ G+ G G G PG PG Sbjct: 525 --PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG------- 575 Query: 466 LTFIDMEG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRF---GVNSSDVPGPAGL 521 ++G G G+L AL G +G GPPG PG PG PG G G PG G Sbjct: 576 -----VKGLPGPKGEL-ALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGT 629 Query: 522 PGVPGREGPPG-------------FPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKG 568 GVPG GPPG PG PGPPGPPG GP G G GSLG+ G PG G Sbjct: 630 QGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPG 689 Query: 569 SKGA--------PGPAGARGESGLAGAPGPAGPPGPPGPPGPPG-PGLPAGFDDME---- 615 G PGP G +G+ G G G G PG G PG PG PGLP + Sbjct: 690 PDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMP 749 Query: 616 -GSGGPFWSTARSADGPQGP---PGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGR- 670 G G P + R G G PGLPGL G PG GL G +G+ G G PG G PGR Sbjct: 750 GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809 Query: 671 ----------EGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQ-- 718 G+ G +G +G RG G KGDPG G+ + G PG G PG + E Sbjct: 810 IEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGP 869 Query: 719 --------DGSVLSVPGPEGRPGFAGFP---GPAGPKGNLGS------------KGERGS 755 + +L PG +G G GFP GP GP GN G+ KG+RG+ Sbjct: 870 LGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929 Query: 756 PGPKGEKGEPGSIFSPD--------------GGALGPAQKGAKGEP------GFRGPPGP 795 PG KGE+G+ G+ + G A P +KG +G P G +G PGP Sbjct: 930 PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989 Query: 796 YGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPG-------DASLGF-GMRGMPGPPGPPGP 847 G PG +G++G G PG PG+ G+ G G G +LGF G G PG PG G Sbjct: 990 AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049 Query: 848 PGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQF------PFDF 901 G G P Y +E +RPGPPG G+ G PG G KGE+G PGPPG Sbjct: 1050 QGDKGEPGY-----SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPG 1104 Query: 902 LQLEAEMKGEKGDRGDAGQK---------GERGEPGGGGFFGS-------------SLPG 939 + G+ G GD G K G RG PG GF GS +PG Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG 1164 Query: 940 PPG----------PPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-IGYEGRQGPPGPPG 988 P G PPGPRG PG G KG+ RG PG PG G G +G G +GP G G Sbjct: 1165 PAGEKGETGLLRAPPGPRGNPGAQGAKGD--RGAPGFPGLPGRKGAMGDAGPRGPTGIEG 1222 Query: 989 PPGPPSFPGP-------HRQTISVPGPPGPPGPPGPPGT 1020 PGPP PG +R G PG PGPPGPPG+ Sbjct: 1223 FPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGS 1261 Score = 470 bits (1209), Expect = e-132 Identities = 340/890 (38%), Positives = 403/890 (45%), Gaps = 195/890 (21%) Query: 309 GAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSPCLPGP- 365 G + LPG + G G + G GL G G PG+PG PG GP G +PG Sbjct: 67 GPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCS 126 Query: 366 --------PGLPCPVSPLG-PAGPALQTVPGPQGPP-----------GPPGRDGTPGRDG 405 PGLP LG P P + G +G P G PG G PG G Sbjct: 127 GSKGEQGFPGLP---GTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQG 183 Query: 406 EPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPG---VGERGPPGPQGPPGPPGPSFR 462 PG PG G G GP GF G PG +GP+G KG G +G +G G +G GPPGP Sbjct: 184 LPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGP--- 240 Query: 463 HDKLTFIDMEGSGFGGDLEALRGPRGF---PGPPGP--------------PGVPGLPGEP 505 + + G DL+ +G +G PGPPGP PG PGL G+P Sbjct: 241 -PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKP 299 Query: 506 GRFGV----NSSDVPGPAGLPGVPGRE---------GPPGF---------------PGLP 537 G+ GV S V G G PG+ G + GPPGF G P Sbjct: 300 GKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTP 359 Query: 538 GPPGP-----------------------PGREGPPGRTGQKGSLGEAGAPGHKGSKGAPG 574 GPPGP PG G PG G KGS GE G PG K + G PG Sbjct: 360 GPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGTPG 418 Query: 575 PAGARGESGLAGAPGPAGPP-------GPPGPPGPPG----PGLPAGFDDMEGSGGPFWS 623 G G GL G+PGP GPP GPPG G PG PG+P G D +G G + Sbjct: 419 SPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIP-GVDGPKGEPGLLCT 477 Query: 624 TARSADGPQGPPGLPGLKGDPGVP------GLPGAKGEVGADGVPGFPGLPGREGIAGPQ 677 GP G PGLPGL G G+P GL G+ G G G+PGFPG PG +G G + Sbjct: 478 QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK 537 Query: 678 GPK-------------GDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVL 723 G K GD G RG+ G G DG+ G PG+ G PGP G + E+ Sbjct: 538 GEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ-- 595 Query: 724 SVPGPEGRPGFAGFPGPAGPKGN-----------LGSKGERGSPGPKGEKGEPG--SIFS 770 GP G PG G PGPAGP G G++G G+PGP GE G G S+ + Sbjct: 596 ---GPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652 Query: 771 PDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGL--------KGE 822 P G GP G G PG +GPPG G G G+ G PG G PG+ G+ KG+ Sbjct: 653 PVPGPPGP--PGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGD 710 Query: 823 KGEPG-DASLG----FGMRGMPGPPGPPGP--------PGPPGTPVY-----DSNVFAES 864 +G PG SLG G G+PG PG PG PG PGTP + +S E Sbjct: 711 QGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEI 770 Query: 865 SRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAE--------MKGEKGDRG 916 PG PGLPG G G G +G+ G PGPPG+ +E + G KG +G Sbjct: 771 GLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQG 830 Query: 917 DAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-- 974 G+ G +G+PG G S PG G PG G+ G GP G+ RG PG PG GPPG Sbjct: 831 RRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ--RGYPGNPGILGPPGED 888 Query: 975 --IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1022 IG G G GPPGPPG P PG R + +PG G G PG G G Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGTPG-QRGSPGIPGVKGQRGTPGAKGEQG 937 Score = 454 bits (1168), Expect = e-127 Identities = 322/796 (40%), Positives = 364/796 (45%), Gaps = 144/796 (18%) Query: 337 GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP-ALQTVPGPQGPPGPP 395 G KG+KGE G PGPPG PG G P GP GP +PG G G Sbjct: 43 GAKGEKGEKGFPGPPGS---------PGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVR 93 Query: 396 GRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPP 454 G G PG G PG P G PG+TGP G G PG G KG++G PG+ G G PG G Sbjct: 94 GISGLPGFSGSPGLP---GTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAA 150 Query: 455 GPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSD 514 G G K I+++ G G L GP+G PGPPG PG G PG PG FG + Sbjct: 151 GLKGQKGAPAKEEDIELDAKGDPG-LPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM 209 Query: 515 VP-GPAGLPG--VPGREGPPGFPGLPGPPGPPGR-----EGPPGRT---GQKGSLGEAGA 563 P GP G G V G +G G GL GPPGPPG GP RT G+KG G G Sbjct: 210 GPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE 269 Query: 564 PGHKGSKGAPGPA-----GARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSG 618 PG G G PG + GA G+ GL G PG G PG PG G G GF + G Sbjct: 270 PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG---NRGFPGLMGED 326 Query: 619 GPFWSTARSADGPQGPPGLPG---------LKGDPGVPGLP---GAKGEVGADGVPGFPG 666 G + G GPPG G KGD G PG P GA+G G G PG PG Sbjct: 327 G-----IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPG 381 Query: 667 LPG--REGIAGPQGPKGDRGSRGEKGDPGKDGVGQ------------PGLPGPPGPPGPV 712 PG R G+ G G G +GS+GE+G PGKD +G PG PGPPGPPG + Sbjct: 382 SPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDI 441 Query: 713 VYVSEQDG----------------------------SVLSVPGPEGRPGFAGFPGPAGPK 744 V+ G +PGP G PG G G G Sbjct: 442 VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIP 501 Query: 745 GNLGSKGERGSPGPKGEKGEPGSIFSPDGGALG-PAQKGAKGEP-------GFRGPPGPY 796 G G+ G +GSPG G G PG F GA G P KG KGE G G PG Sbjct: 502 GRQGAAGLKGSPGSPGNTGLPG--FPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLR 559 Query: 797 GRPGYKGEIGFPGRPGRPGMNGLKGE---KGEPGDASLGFGMRGMPGPPGPPGPPGPPGT 853 G+PG KG G PG PG G+ G KGE GE GD G G PG PG PGP GP G Sbjct: 560 GQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ----GPPGDPGSPGSPGPAGPAGP 615 Query: 854 PVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEV-------GPPGPPGQFPFDFLQLEA 906 P Y E G G+PG GPPG G +GE+ GPPGPPG Q Sbjct: 616 PGYGPQ--GEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPP 673 Query: 907 EMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYP------GIPGPKGE-S 959 + G G GD G G GEP G G PGPPGP G +G+P G PG GE Sbjct: 674 GIPGSLGKCGDPGLPGPDGEP---GIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPG 730 Query: 960 IRGQPGPPGPQGPPGIGYEGRQGPPGPPGP------------PGPPSFPG-PHRQTISVP 1006 + G+PG PG +G P + G G PG PG PG P PG P + + Sbjct: 731 LPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNE--GLD 788 Query: 1007 GPPGPPGPPGPPGTMG 1022 GP G PG PGPPG G Sbjct: 789 GPRGDPGQPGPPGEQG 804 Score = 404 bits (1038), Expect = e-112 Identities = 289/717 (40%), Positives = 332/717 (46%), Gaps = 161/717 (22%) Query: 436 DKG----DPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPG 491 DKG D GE+G G GPPG PG GF GP G PG Sbjct: 35 DKGQCFCDGAKGEKGEKGFPGPPGSPGQK--------------GF-------TGPEGLPG 73 Query: 492 PPGPPGVPGLPGEPGRFGVNS-SDVPG---PAGLPGVPGREGPPGFPGLPGPPGPPGREG 547 P GP G PGLPG G GV S +PG GLPG PG GP G G+PG G G +G Sbjct: 74 PQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQG 133 Query: 548 PPGRTGQKGSLGEAGAPGHKGSKGAPGPA-----GARGESGLAGAPGPAGPPGPPGPPGP 602 PG G G G GA G KG KGAP A+G+ GL GAPGP G PGPPG PGP Sbjct: 134 FPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGP 193 Query: 603 PGPGLPAGFDDMEGSGGPFWSTARSAD---------------GPQGPPG----------- 636 GP P GF G+ GP + GP GPPG Sbjct: 194 VGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDN 253 Query: 637 ---LPGLKGDPGVPGLPGAKG-----------EVGADGVPGFPGLPGREGIAGPQGPKGD 682 L G KGD G G PG G E GA G PG G PG++G+ G G +G Sbjct: 254 RTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGV 313 Query: 683 RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSE-QDGSVLSVPGPEGRPGFAGFPGP 740 +G+RG G G+DG+ GQ G GPPG GP Y Q+ PGP G G G GP Sbjct: 314 KGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGP 373 Query: 741 AGPKGNLGSKGE-----RGSPGPKGEKGEPGSIFSPDGGALG----PAQKGAKGEPGFRG 791 +GP G GS G RG+PG G KG G P A+G P G+ G PG G Sbjct: 374 SGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPG 433 Query: 792 PPGPYG----RPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLG--------------- 832 PPGP G R G G+ G PG G PG+ G+ G KGEPG Sbjct: 434 PPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493 Query: 833 -FGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE---- 887 G++G+PG G G G PG+P + PG PG PG QG PG KG KGE Sbjct: 494 LHGVKGIPGRQGAAGLKGSPGSP-------GNTGLPGFPGFPGAQGDPGLKGEKGETLQP 546 Query: 888 ---VGPPGPPG------QFPFDFLQLEAEMKGEKGDRGD---AGQKGERGEPGGGGFFGS 935 VG PG PG + D + +KG G +G+ +G+KG++G PG G GS Sbjct: 547 EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606 Query: 936 SLPGPPGPPGPRGY--------------PGIPGPKGES-IRGQ-------PGPPGPQGPP 973 PGP GP GP GY PG PGP GE+ RG+ PGPPGP GPP Sbjct: 607 --PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664 Query: 974 GIGYEGRQGPPGPP---GPPGPPSFPGPHRQT----ISVPGPPGPPGPPGPPGTMGA 1023 G + G QGPPG P G G P PGP + I PGPPGP G G PGT G+ Sbjct: 665 G--HPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719 Score = 385 bits (990), Expect = e-106 Identities = 274/701 (39%), Positives = 309/701 (44%), Gaps = 147/701 (20%) Query: 272 PRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGG 331 P P PP PP G E R GAQ LPG + + G G Sbjct: 794 PGQPGPPGEQGPP---GRCIEGPR-------------GAQGLPGLNGLKGQQGRRGKTGP 837 Query: 332 RVKEG-------GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQT 384 + G G G+ G PG+PG G GP G PG PG+ P G G + Sbjct: 838 KGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIG--MMG 895 Query: 385 VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPK------GDKG 438 PG GPPGPPG GTPG+ G PG PG G+ G G +G G G+ GP GDKG Sbjct: 896 FPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKG 955 Query: 439 DPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP----- 492 +PG+ G G PG +G G PG G G L+ L GP G PGP Sbjct: 956 EPGLKGFAGNPGEKGNRGVPGMP--------------GLKG-LKGLPGPAGPPGPRGDLG 1000 Query: 493 ----PGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGL------------ 536 PG PG+ G+PG G G+ S G G G PGR G PG PG+ Sbjct: 1001 STGNPGEPGLRGIPGSMGNMGMPGSK--GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGY 1058 Query: 537 -----PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGP- 590 PGPPGP G G PG G+KG +G+ G PGH G G G G+ G GL G PGP Sbjct: 1059 SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPH 1118 Query: 591 -----------AGPPGPPGPPGPPG-PGLPA--------GFDDMEGSGGPFWSTA--RSA 628 GPPG GPPG PG PG P G D + G G T R+ Sbjct: 1119 GDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAP 1178 Query: 629 DGPQGPPGLPGLKGD---PGVPGLPGAKGEVG---------ADGVPGFPGLPGR--EGIA 674 GP+G PG G KGD PG PGLPG KG +G +G PG PGLPG G Sbjct: 1179 PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT 1238 Query: 675 GPQGPKGDRGSRGEKGDPGKDGV---------GQPGLPGPPGPPGPVVYVSEQDG----S 721 G +GP G RGS G G PG G G G PGP GPPG + Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPG 1298 Query: 722 VLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGAL----- 776 +PGP G PGF GFPG G KGN G G G PGP G KG PG D G L Sbjct: 1299 TPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG--VRGDPGTLKIISL 1356 Query: 777 --GPAQKGAKGEPGFRGPPGPYGRPGY---------KGEIGFPGRPGRPGMNGLKGEKGE 825 P G GEPG +G PGP G PG G+ G PG PG G G KG KGE Sbjct: 1357 PGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGE 1416 Query: 826 PGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR 866 PG A G G+PG G G G P T VF S+ Sbjct: 1417 PGPA----GSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQ 1453 Score = 338 bits (868), Expect = 2e-92 Identities = 242/644 (37%), Positives = 286/644 (44%), Gaps = 119/644 (18%) Query: 241 GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 300 G D G G++GS + E G + P P + PP G + Sbjct: 845 GLDRSGFPGETGSPGIPGHQ---GEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIG 901 Query: 301 EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGG-----------LKGQKGEPGV-- 347 + G GS + G TPG + ++G + G KGEPG+ Sbjct: 902 PPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKG 961 Query: 348 ----PGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG----------PALQTVPGPQGPPG 393 PG G G PG P L G GLP P P GP G P L+ +PG G G Sbjct: 962 FAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMG 1021 Query: 394 PPGRDGT------PGRDGEPGDPGEDG--------------KPGDTGPQGFPGTPGDVGP 433 PG G PGR G PG PG G +PG GP G PG PGD+G Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGK 1081 Query: 434 KGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP 492 KG+ G PG G GP GP+G PG PG K G GDL +G +G GP Sbjct: 1082 KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK--------PGPHGDL-GFKGIKGLLGP 1132 Query: 493 PG---PPGVPGLPGEPGRFGVNSSD----VPGPAGLPGVPGR----EGPPGFPGLPGPPG 541 PG PPG+PG PG PG G+ +PGPAG G G GP G PG G G Sbjct: 1133 PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKG 1192 Query: 542 PPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARG-----ESGLAGAPGPAGPPGP 596 G G PG G+KG++G+AG G G +G PGP G G ++G G PG G PG Sbjct: 1193 DRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGA 1252 Query: 597 PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGL------PGLKGDPGVPGLP 650 PGPPGPPG + D G P GP+GPPG PG G PG PGLP Sbjct: 1253 PGPPGPPGSHVIGIKGDKGSMGHP---------GPKGPPGTAGDMGPPGRLGAPGTPGLP 1303 Query: 651 GAKGEVGADGVPGFPGL---PGREGIAGPQGPKGDRGSRGEKGDPGK-DGVGQPGLPGPP 706 G +G+ G G PG G PG G GP GP G +G G +GDPG + PG PGPP Sbjct: 1304 GPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPP 1363 Query: 707 GPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPG---PAGPKGNLGSKGERGSPGPKGEKG 763 G PG PG +G PG G PG P GP+G G G+ G+PGP GEKG Sbjct: 1364 GTPGE--------------PGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409 Query: 764 EPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGF 807 GS P GPA G+ G PG +G G G P GF Sbjct: 1410 NKGSKGEP-----GPA--GSDGLPGLKGKRGDSGSPATWTTRGF 1446 Score = 276 bits (706), Expect = 1e-73 Identities = 201/508 (39%), Positives = 230/508 (45%), Gaps = 106/508 (20%) Query: 567 KGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTAR 626 KG G G +GE G G PG G G GP G PGP P GF + G G Sbjct: 36 KGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTG------- 88 Query: 627 SADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPG---------FPGLP---GREGIA 674 + G +G GLPG G PG+PG PG G G GVPG FPGLP G GI Sbjct: 89 -SKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIP 147 Query: 675 GPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGF 734 G G KG +G+ ++ D D G PGLPG PGP+G PG Sbjct: 148 GAAGLKGQKGAPAKEEDIELDAKGDPGLPG--------------------APGPQGLPGP 187 Query: 735 AGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPG 794 GFPGP GP G G G G+ GP+G KG G +G KG +G G GPPG Sbjct: 188 PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGE------RVIG--HKGERGVKGLTGPPG 239 Query: 795 PYGR--------------PGYKGEIGFPGRPGRPGMNGLKGE-----KGEPGDASLGFGM 835 P G G KG+ G G PG PG +GL GE KG PGD G+ Sbjct: 240 PPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDP----GL 295 Query: 836 RGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPG 895 +G PG G PG PG G G G PG G G KG KG++GPPG G Sbjct: 296 QGKPGKDGVPGFPGSEGVK-------------GNRGFPGLMGEDGIKGQKGDIGPPGFRG 342 Query: 896 QFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGP--PGPRGYPGIP 953 P ++ E KG++G G G +G RG G G G +PG PG PG RG PG P Sbjct: 343 --PTEYYDTYQE-KGDEGTPGPPGPRGARGPQGPSGPPG--VPGSPGSSRPGLRGAPGWP 397 Query: 954 GPKG-ESIRGQPGPP--GPQGPPGI-GYEGRQGPPGPPGPPGPPSF----PGPHRQTISV 1005 G KG + RG+PG G G PG G G G PGPPGPPG F PG H Sbjct: 398 GLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH------ 451 Query: 1006 PGPPGPPGPPGPPGTMGASSGVRLWATR 1033 G PG G PG PG G L T+ Sbjct: 452 -GLPGYLGSPGIPGVDGPKGEPGLLCTQ 478 Score = 168 bits (426), Expect = 3e-41 Identities = 118/312 (37%), Positives = 134/312 (42%), Gaps = 72/312 (23%) Query: 766 GSIFSPDGGALGPAQKGAKGEPGFRGPP---------GPYGRPGYKGEIGFPGRPGRPGM 816 G + G KG KGE GF GPP GP G PG +G GFPG PG G Sbjct: 30 GCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGS 89 Query: 817 NGLKGEKGEPGDASLGFGMRGMPGPPGPPGP------------------PGPPGT----- 853 G++G G PG + G G+PG PG GP PG PGT Sbjct: 90 KGVRGISGLPGFS----GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145 Query: 854 -------------PVYDSNVFAES-SRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPF 899 P + ++ ++ PG PG PG QG PGP G G VGPPGPPG F F Sbjct: 146 IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205 Query: 900 DFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPP--------GPRGYPG 951 KG G+R G KGERG G L GPPGPP GP Sbjct: 206 PGAMGPRGPKGHMGER-VIGHKGERGVKG--------LTGPPGPPGTVIVTLTGPDNRTD 256 Query: 952 IPGPKGE-SIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPG 1010 + G KG+ G+PGPPGP G PG Y +G PG PG G P G PG G Sbjct: 257 LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDG----VPGFPGSEG 312 Query: 1011 PPGPPGPPGTMG 1022 G G PG MG Sbjct: 313 VKGNRGFPGLMG 324 >gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo sapiens] Length = 1637 Score = 512 bits (1318), Expect = e-144 Identities = 357/880 (40%), Positives = 410/880 (46%), Gaps = 160/880 (18%) Query: 246 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 305 G GD G LR + G +P P V P G E + S E +Q Sbjct: 551 GVPGDPG---------LRGQPGRKGLDGIPGTPGVKGLP---GPKGELALSGEKGDQGPP 598 Query: 306 ASLGAQTLPGSDSVSTWDGSVRTPG-GRVKEGGLKGQKGEPGVPGPPGRAGPPG----SP 360 G+ PG G PG G E GL+G +G PG PGPPG AGP G S Sbjct: 599 GDPGSPGSPGPA------GPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652 Query: 361 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGR------DGTPGRDGEPGDPGED- 413 +PGPPG P GP G PGPQGPPG PG G PG DGEPG PG Sbjct: 653 PVPGPPGPP------GPPGH-----PGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF 701 Query: 414 -GKPGDTGPQGFPGT---------------PGDVGPKGDKGDPGVGERGPPGPQGPPGPP 457 G PG G QGFPGT PG G G KG+P V G PG G PG Sbjct: 702 PGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGER 761 Query: 458 GPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPG 517 G S H ++ + G E L GPRG PG PGPPG G PG + +PG Sbjct: 762 GNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPG 821 Query: 518 PAGLPGVPGREG---PPGFPGLPG--PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA 572 GL G GR G P G PG+PG G PG G PG G +G +G G G+ G+ G Sbjct: 822 LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGI 881 Query: 573 PGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGLPAGFDDMEGSGGPFWSTARSA 628 GP G G G+ G PG GPPGPPG PG PG PG+P G G+ G A+ Sbjct: 882 LGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIP-GVKGQRGTPG-----AKGE 935 Query: 629 DGPQGPPG------LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGD 682 G +G PG + G KG+PG+ G G GE G GVPG PGL G +G+ GP GP G Sbjct: 936 QGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGP 995 Query: 683 RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGF---- 737 RG G G+PG+ G+ G PG G G PG S+ L PG GRPG G Sbjct: 996 RGDLGSTGNPGEPGLRGIPGSMGNMGMPG-----SKGKRGTLGFPGRAGRPGLPGIHGLQ 1050 Query: 738 -------------PGPAGPKGN------LGSKGERGSPGPKGE------KGEPGSIFSPD 772 PGP GP G+ +G KGE G PGP G +G PGS SP Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110 Query: 773 -GGALGP-------AQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG 824 G GP KG G PG RGPPG G PG G +G G GR G+ G GEKG Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170 Query: 825 EPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR-----------PGPPGLP 873 E G G RG PG G G G PG P A PGPPGLP Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230 Query: 874 G--------NQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERG 925 G N+GPPG +G+ G GPPGPPG + + G KGD+G G G +G Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPG----------SHVIGIKGDKGSMGHPGPKG 1280 Query: 926 EPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE-SIRGQPGPPGPQGPPGIGYEGRQGPP 984 PG G G PPG G G PG+PGP+G+ +G PG G +G PG + G GPP Sbjct: 1281 PPGTAGDMG-----PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG--FLGSIGPP 1333 Query: 985 GPPGPPGPPSFPGPHR--QTISVPGPPGPPGPPGPPGTMG 1022 GP GP GPP G + IS+PG PGPPG PG PG G Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373 Score = 480 bits (1235), Expect = e-135 Identities = 351/939 (37%), Positives = 415/939 (44%), Gaps = 186/939 (19%) Query: 243 DSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQ 302 D+ GD G+ R G + P +P P + P L G + + E Sbjct: 348 DTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERG 407 Query: 303 TTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCL 362 A PGS + G +PG G + +KG PG G PG G PG P + Sbjct: 408 RP--GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGV 465 Query: 363 PGP---PGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT 419 GP PGL C P P P L +PG G G PGR G G G PG PG G PG Sbjct: 466 DGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGF- 524 Query: 420 GPQGFPGTPGDVGPKGDK-------------GDPGV-GERGPPGPQGPPGPPGPSFRHDK 465 GFPG GD G KG+K GDPG+ G+ G G G PG PG Sbjct: 525 --PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG------- 575 Query: 466 LTFIDMEG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRF---GVNSSDVPGPAGL 521 ++G G G+L AL G +G GPPG PG PG PG G G PG G Sbjct: 576 -----VKGLPGPKGEL-ALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGT 629 Query: 522 PGVPGREGPPG-------------FPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKG 568 GVPG GPPG PG PGPPGPPG GP G G GSLG+ G PG G Sbjct: 630 QGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPG 689 Query: 569 SKGA--------PGPAGARGESGLAGAPGPAGPPGPPGPPGPPG-PGLPAGFDDME---- 615 G PGP G +G+ G G G G PG G PG PG PGLP + Sbjct: 690 PDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMP 749 Query: 616 -GSGGPFWSTARSADGPQGP---PGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGR- 670 G G P + R G G PGLPGL G PG GL G +G+ G G PG G PGR Sbjct: 750 GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809 Query: 671 ----------EGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQ-- 718 G+ G +G +G RG G KGDPG G+ + G PG G PG + E Sbjct: 810 IEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGP 869 Query: 719 --------DGSVLSVPGPEGRPGFAGFP---GPAGPKGNLGS------------KGERGS 755 + +L PG +G G GFP GP GP GN G+ KG+RG+ Sbjct: 870 LGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929 Query: 756 PGPKGEKGEPGSIFSPD--------------GGALGPAQKGAKGEP------GFRGPPGP 795 PG KGE+G+ G+ + G A P +KG +G P G +G PGP Sbjct: 930 PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989 Query: 796 YGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPG-------DASLGF-GMRGMPGPPGPPGP 847 G PG +G++G G PG PG+ G+ G G G +LGF G G PG PG G Sbjct: 990 AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049 Query: 848 PGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQF------PFDF 901 G G P Y +E +RPGPPG G+ G PG G KGE+G PGPPG Sbjct: 1050 QGDKGEPGY-----SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPG 1104 Query: 902 LQLEAEMKGEKGDRGDAGQK---------GERGEPGGGGFFGS-------------SLPG 939 + G+ G GD G K G RG PG GF GS +PG Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG 1164 Query: 940 PPG----------PPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-IGYEGRQGPPGPPG 988 P G PPGPRG PG G KG+ RG PG PG G G +G G +GP G G Sbjct: 1165 PAGEKGETGLLRAPPGPRGNPGAQGAKGD--RGAPGFPGLPGRKGAMGDAGPRGPTGIEG 1222 Query: 989 PPGPPSFPGP-------HRQTISVPGPPGPPGPPGPPGT 1020 PGPP PG +R G PG PGPPGPPG+ Sbjct: 1223 FPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGS 1261 Score = 470 bits (1209), Expect = e-132 Identities = 340/890 (38%), Positives = 403/890 (45%), Gaps = 195/890 (21%) Query: 309 GAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSPCLPGP- 365 G + LPG + G G + G GL G G PG+PG PG GP G +PG Sbjct: 67 GPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCS 126 Query: 366 --------PGLPCPVSPLG-PAGPALQTVPGPQGPP-----------GPPGRDGTPGRDG 405 PGLP LG P P + G +G P G PG G PG G Sbjct: 127 GSKGEQGFPGLP---GTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQG 183 Query: 406 EPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPG---VGERGPPGPQGPPGPPGPSFR 462 PG PG G G GP GF G PG +GP+G KG G +G +G G +G GPPGP Sbjct: 184 LPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGP--- 240 Query: 463 HDKLTFIDMEGSGFGGDLEALRGPRGF---PGPPGP--------------PGVPGLPGEP 505 + + G DL+ +G +G PGPPGP PG PGL G+P Sbjct: 241 -PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKP 299 Query: 506 GRFGV----NSSDVPGPAGLPGVPGRE---------GPPGF---------------PGLP 537 G+ GV S V G G PG+ G + GPPGF G P Sbjct: 300 GKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTP 359 Query: 538 GPPGP-----------------------PGREGPPGRTGQKGSLGEAGAPGHKGSKGAPG 574 GPPGP PG G PG G KGS GE G PG K + G PG Sbjct: 360 GPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGTPG 418 Query: 575 PAGARGESGLAGAPGPAGPP-------GPPGPPGPPG----PGLPAGFDDMEGSGGPFWS 623 G G GL G+PGP GPP GPPG G PG PG+P G D +G G + Sbjct: 419 SPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIP-GVDGPKGEPGLLCT 477 Query: 624 TARSADGPQGPPGLPGLKGDPGVP------GLPGAKGEVGADGVPGFPGLPGREGIAGPQ 677 GP G PGLPGL G G+P GL G+ G G G+PGFPG PG +G G + Sbjct: 478 QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK 537 Query: 678 GPK-------------GDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVL 723 G K GD G RG+ G G DG+ G PG+ G PGP G + E+ Sbjct: 538 GEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ-- 595 Query: 724 SVPGPEGRPGFAGFPGPAGPKGN-----------LGSKGERGSPGPKGEKGEPG--SIFS 770 GP G PG G PGPAGP G G++G G+PGP GE G G S+ + Sbjct: 596 ---GPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652 Query: 771 PDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGL--------KGE 822 P G GP G G PG +GPPG G G G+ G PG G PG+ G+ KG+ Sbjct: 653 PVPGPPGP--PGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGD 710 Query: 823 KGEPG-DASLG----FGMRGMPGPPGPPGP--------PGPPGTPVY-----DSNVFAES 864 +G PG SLG G G+PG PG PG PG PGTP + +S E Sbjct: 711 QGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEI 770 Query: 865 SRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAE--------MKGEKGDRG 916 PG PGLPG G G G +G+ G PGPPG+ +E + G KG +G Sbjct: 771 GLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQG 830 Query: 917 DAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-- 974 G+ G +G+PG G S PG G PG G+ G GP G+ RG PG PG GPPG Sbjct: 831 RRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ--RGYPGNPGILGPPGED 888 Query: 975 --IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1022 IG G G GPPGPPG P PG R + +PG G G PG G G Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGTPG-QRGSPGIPGVKGQRGTPGAKGEQG 937 Score = 454 bits (1168), Expect = e-127 Identities = 322/796 (40%), Positives = 364/796 (45%), Gaps = 144/796 (18%) Query: 337 GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP-ALQTVPGPQGPPGPP 395 G KG+KGE G PGPPG PG G P GP GP +PG G G Sbjct: 43 GAKGEKGEKGFPGPPGS---------PGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVR 93 Query: 396 GRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPP 454 G G PG G PG P G PG+TGP G G PG G KG++G PG+ G G PG G Sbjct: 94 GISGLPGFSGSPGLP---GTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAA 150 Query: 455 GPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSD 514 G G K I+++ G G L GP+G PGPPG PG G PG PG FG + Sbjct: 151 GLKGQKGAPAKEEDIELDAKGDPG-LPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM 209 Query: 515 VP-GPAGLPG--VPGREGPPGFPGLPGPPGPPGR-----EGPPGRT---GQKGSLGEAGA 563 P GP G G V G +G G GL GPPGPPG GP RT G+KG G G Sbjct: 210 GPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE 269 Query: 564 PGHKGSKGAPGPA-----GARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSG 618 PG G G PG + GA G+ GL G PG G PG PG G G GF + G Sbjct: 270 PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG---NRGFPGLMGED 326 Query: 619 GPFWSTARSADGPQGPPGLPG---------LKGDPGVPGLP---GAKGEVGADGVPGFPG 666 G + G GPPG G KGD G PG P GA+G G G PG PG Sbjct: 327 G-----IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPG 381 Query: 667 LPG--REGIAGPQGPKGDRGSRGEKGDPGKDGVGQ------------PGLPGPPGPPGPV 712 PG R G+ G G G +GS+GE+G PGKD +G PG PGPPGPPG + Sbjct: 382 SPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDI 441 Query: 713 VYVSEQDG----------------------------SVLSVPGPEGRPGFAGFPGPAGPK 744 V+ G +PGP G PG G G G Sbjct: 442 VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIP 501 Query: 745 GNLGSKGERGSPGPKGEKGEPGSIFSPDGGALG-PAQKGAKGEP-------GFRGPPGPY 796 G G+ G +GSPG G G PG F GA G P KG KGE G G PG Sbjct: 502 GRQGAAGLKGSPGSPGNTGLPG--FPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLR 559 Query: 797 GRPGYKGEIGFPGRPGRPGMNGLKGE---KGEPGDASLGFGMRGMPGPPGPPGPPGPPGT 853 G+PG KG G PG PG G+ G KGE GE GD G G PG PG PGP GP G Sbjct: 560 GQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ----GPPGDPGSPGSPGPAGPAGP 615 Query: 854 PVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEV-------GPPGPPGQFPFDFLQLEA 906 P Y E G G+PG GPPG G +GE+ GPPGPPG Q Sbjct: 616 PGYGPQ--GEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPP 673 Query: 907 EMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYP------GIPGPKGE-S 959 + G G GD G G GEP G G PGPPGP G +G+P G PG GE Sbjct: 674 GIPGSLGKCGDPGLPGPDGEP---GIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPG 730 Query: 960 IRGQPGPPGPQGPPGIGYEGRQGPPGPPGP------------PGPPSFPG-PHRQTISVP 1006 + G+PG PG +G P + G G PG PG PG P PG P + + Sbjct: 731 LPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNE--GLD 788 Query: 1007 GPPGPPGPPGPPGTMG 1022 GP G PG PGPPG G Sbjct: 789 GPRGDPGQPGPPGEQG 804 Score = 404 bits (1038), Expect = e-112 Identities = 289/717 (40%), Positives = 332/717 (46%), Gaps = 161/717 (22%) Query: 436 DKG----DPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPG 491 DKG D GE+G G GPPG PG GF GP G PG Sbjct: 35 DKGQCFCDGAKGEKGEKGFPGPPGSPGQK--------------GF-------TGPEGLPG 73 Query: 492 PPGPPGVPGLPGEPGRFGVNS-SDVPG---PAGLPGVPGREGPPGFPGLPGPPGPPGREG 547 P GP G PGLPG G GV S +PG GLPG PG GP G G+PG G G +G Sbjct: 74 PQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQG 133 Query: 548 PPGRTGQKGSLGEAGAPGHKGSKGAPGPA-----GARGESGLAGAPGPAGPPGPPGPPGP 602 PG G G G GA G KG KGAP A+G+ GL GAPGP G PGPPG PGP Sbjct: 134 FPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGP 193 Query: 603 PGPGLPAGFDDMEGSGGPFWSTARSAD---------------GPQGPPG----------- 636 GP P GF G+ GP + GP GPPG Sbjct: 194 VGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDN 253 Query: 637 ---LPGLKGDPGVPGLPGAKG-----------EVGADGVPGFPGLPGREGIAGPQGPKGD 682 L G KGD G G PG G E GA G PG G PG++G+ G G +G Sbjct: 254 RTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGV 313 Query: 683 RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSE-QDGSVLSVPGPEGRPGFAGFPGP 740 +G+RG G G+DG+ GQ G GPPG GP Y Q+ PGP G G G GP Sbjct: 314 KGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGP 373 Query: 741 AGPKGNLGSKGE-----RGSPGPKGEKGEPGSIFSPDGGALG----PAQKGAKGEPGFRG 791 +GP G GS G RG+PG G KG G P A+G P G+ G PG G Sbjct: 374 SGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPG 433 Query: 792 PPGPYG----RPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLG--------------- 832 PPGP G R G G+ G PG G PG+ G+ G KGEPG Sbjct: 434 PPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493 Query: 833 -FGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE---- 887 G++G+PG G G G PG+P + PG PG PG QG PG KG KGE Sbjct: 494 LHGVKGIPGRQGAAGLKGSPGSP-------GNTGLPGFPGFPGAQGDPGLKGEKGETLQP 546 Query: 888 ---VGPPGPPG------QFPFDFLQLEAEMKGEKGDRGD---AGQKGERGEPGGGGFFGS 935 VG PG PG + D + +KG G +G+ +G+KG++G PG G GS Sbjct: 547 EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606 Query: 936 SLPGPPGPPGPRGY--------------PGIPGPKGES-IRGQ-------PGPPGPQGPP 973 PGP GP GP GY PG PGP GE+ RG+ PGPPGP GPP Sbjct: 607 --PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664 Query: 974 GIGYEGRQGPPGPP---GPPGPPSFPGPHRQT----ISVPGPPGPPGPPGPPGTMGA 1023 G + G QGPPG P G G P PGP + I PGPPGP G G PGT G+ Sbjct: 665 G--HPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719 Score = 385 bits (990), Expect = e-106 Identities = 274/701 (39%), Positives = 309/701 (44%), Gaps = 147/701 (20%) Query: 272 PRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGG 331 P P PP PP G E R GAQ LPG + + G G Sbjct: 794 PGQPGPPGEQGPP---GRCIEGPR-------------GAQGLPGLNGLKGQQGRRGKTGP 837 Query: 332 RVKEG-------GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQT 384 + G G G+ G PG+PG G GP G PG PG+ P G G + Sbjct: 838 KGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIG--MMG 895 Query: 385 VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPK------GDKG 438 PG GPPGPPG GTPG+ G PG PG G+ G G +G G G+ GP GDKG Sbjct: 896 FPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKG 955 Query: 439 DPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP----- 492 +PG+ G G PG +G G PG G G L+ L GP G PGP Sbjct: 956 EPGLKGFAGNPGEKGNRGVPGMP--------------GLKG-LKGLPGPAGPPGPRGDLG 1000 Query: 493 ----PGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGL------------ 536 PG PG+ G+PG G G+ S G G G PGR G PG PG+ Sbjct: 1001 STGNPGEPGLRGIPGSMGNMGMPGSK--GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGY 1058 Query: 537 -----PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGP- 590 PGPPGP G G PG G+KG +G+ G PGH G G G G+ G GL G PGP Sbjct: 1059 SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPH 1118 Query: 591 -----------AGPPGPPGPPGPPG-PGLPA--------GFDDMEGSGGPFWSTA--RSA 628 GPPG GPPG PG PG P G D + G G T R+ Sbjct: 1119 GDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAP 1178 Query: 629 DGPQGPPGLPGLKGD---PGVPGLPGAKGEVG---------ADGVPGFPGLPGR--EGIA 674 GP+G PG G KGD PG PGLPG KG +G +G PG PGLPG G Sbjct: 1179 PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT 1238 Query: 675 GPQGPKGDRGSRGEKGDPGKDGV---------GQPGLPGPPGPPGPVVYVSEQDG----S 721 G +GP G RGS G G PG G G G PGP GPPG + Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPG 1298 Query: 722 VLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGAL----- 776 +PGP G PGF GFPG G KGN G G G PGP G KG PG D G L Sbjct: 1299 TPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG--VRGDPGTLKIISL 1356 Query: 777 --GPAQKGAKGEPGFRGPPGPYGRPGY---------KGEIGFPGRPGRPGMNGLKGEKGE 825 P G GEPG +G PGP G PG G+ G PG PG G G KG KGE Sbjct: 1357 PGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGE 1416 Query: 826 PGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR 866 PG A G G+PG G G G P T VF S+ Sbjct: 1417 PGPA----GSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQ 1453 Score = 338 bits (868), Expect = 2e-92 Identities = 242/644 (37%), Positives = 286/644 (44%), Gaps = 119/644 (18%) Query: 241 GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 300 G D G G++GS + E G + P P + PP G + Sbjct: 845 GLDRSGFPGETGSPGIPGHQ---GEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIG 901 Query: 301 EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGG-----------LKGQKGEPGV-- 347 + G GS + G TPG + ++G + G KGEPG+ Sbjct: 902 PPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKG 961 Query: 348 ----PGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG----------PALQTVPGPQGPPG 393 PG G G PG P L G GLP P P GP G P L+ +PG G G Sbjct: 962 FAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMG 1021 Query: 394 PPGRDGT------PGRDGEPGDPGEDG--------------KPGDTGPQGFPGTPGDVGP 433 PG G PGR G PG PG G +PG GP G PG PGD+G Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGK 1081 Query: 434 KGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP 492 KG+ G PG G GP GP+G PG PG K G GDL +G +G GP Sbjct: 1082 KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK--------PGPHGDL-GFKGIKGLLGP 1132 Query: 493 PG---PPGVPGLPGEPGRFGVNSSD----VPGPAGLPGVPGR----EGPPGFPGLPGPPG 541 PG PPG+PG PG PG G+ +PGPAG G G GP G PG G G Sbjct: 1133 PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKG 1192 Query: 542 PPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARG-----ESGLAGAPGPAGPPGP 596 G G PG G+KG++G+AG G G +G PGP G G ++G G PG G PG Sbjct: 1193 DRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGA 1252 Query: 597 PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGL------PGLKGDPGVPGLP 650 PGPPGPPG + D G P GP+GPPG PG G PG PGLP Sbjct: 1253 PGPPGPPGSHVIGIKGDKGSMGHP---------GPKGPPGTAGDMGPPGRLGAPGTPGLP 1303 Query: 651 GAKGEVGADGVPGFPGL---PGREGIAGPQGPKGDRGSRGEKGDPGK-DGVGQPGLPGPP 706 G +G+ G G PG G PG G GP GP G +G G +GDPG + PG PGPP Sbjct: 1304 GPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPP 1363 Query: 707 GPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPG---PAGPKGNLGSKGERGSPGPKGEKG 763 G PG PG +G PG G PG P GP+G G G+ G+PGP GEKG Sbjct: 1364 GTPGE--------------PGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409 Query: 764 EPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGF 807 GS P GPA G+ G PG +G G G P GF Sbjct: 1410 NKGSKGEP-----GPA--GSDGLPGLKGKRGDSGSPATWTTRGF 1446 Score = 276 bits (706), Expect = 1e-73 Identities = 201/508 (39%), Positives = 230/508 (45%), Gaps = 106/508 (20%) Query: 567 KGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTAR 626 KG G G +GE G G PG G G GP G PGP P GF + G G Sbjct: 36 KGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTG------- 88 Query: 627 SADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPG---------FPGLP---GREGIA 674 + G +G GLPG G PG+PG PG G G GVPG FPGLP G GI Sbjct: 89 -SKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIP 147 Query: 675 GPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGF 734 G G KG +G+ ++ D D G PGLPG PGP+G PG Sbjct: 148 GAAGLKGQKGAPAKEEDIELDAKGDPGLPG--------------------APGPQGLPGP 187 Query: 735 AGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPG 794 GFPGP GP G G G G+ GP+G KG G +G KG +G G GPPG Sbjct: 188 PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGE------RVIG--HKGERGVKGLTGPPG 239 Query: 795 PYGR--------------PGYKGEIGFPGRPGRPGMNGLKGE-----KGEPGDASLGFGM 835 P G G KG+ G G PG PG +GL GE KG PGD G+ Sbjct: 240 PPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDP----GL 295 Query: 836 RGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPG 895 +G PG G PG PG G G G PG G G KG KG++GPPG G Sbjct: 296 QGKPGKDGVPGFPGSEGVK-------------GNRGFPGLMGEDGIKGQKGDIGPPGFRG 342 Query: 896 QFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGP--PGPRGYPGIP 953 P ++ E KG++G G G +G RG G G G +PG PG PG RG PG P Sbjct: 343 --PTEYYDTYQE-KGDEGTPGPPGPRGARGPQGPSGPPG--VPGSPGSSRPGLRGAPGWP 397 Query: 954 GPKG-ESIRGQPGPP--GPQGPPGI-GYEGRQGPPGPPGPPGPPSF----PGPHRQTISV 1005 G KG + RG+PG G G PG G G G PGPPGPPG F PG H Sbjct: 398 GLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH------ 451 Query: 1006 PGPPGPPGPPGPPGTMGASSGVRLWATR 1033 G PG G PG PG G L T+ Sbjct: 452 -GLPGYLGSPGIPGVDGPKGEPGLLCTQ 478 Score = 168 bits (426), Expect = 3e-41 Identities = 118/312 (37%), Positives = 134/312 (42%), Gaps = 72/312 (23%) Query: 766 GSIFSPDGGALGPAQKGAKGEPGFRGPP---------GPYGRPGYKGEIGFPGRPGRPGM 816 G + G KG KGE GF GPP GP G PG +G GFPG PG G Sbjct: 30 GCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGS 89 Query: 817 NGLKGEKGEPGDASLGFGMRGMPGPPGPPGP------------------PGPPGT----- 853 G++G G PG + G G+PG PG GP PG PGT Sbjct: 90 KGVRGISGLPGFS----GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145 Query: 854 -------------PVYDSNVFAES-SRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPF 899 P + ++ ++ PG PG PG QG PGP G G VGPPGPPG F F Sbjct: 146 IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205 Query: 900 DFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPP--------GPRGYPG 951 KG G+R G KGERG G L GPPGPP GP Sbjct: 206 PGAMGPRGPKGHMGER-VIGHKGERGVKG--------LTGPPGPPGTVIVTLTGPDNRTD 256 Query: 952 IPGPKGE-SIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPG 1010 + G KG+ G+PGPPGP G PG Y +G PG PG G P G PG G Sbjct: 257 LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDG----VPGFPGSEG 312 Query: 1011 PPGPPGPPGTMG 1022 G G PG MG Sbjct: 313 VKGNRGFPGLMG 324 >gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo sapiens] Length = 1670 Score = 512 bits (1318), Expect = e-144 Identities = 357/880 (40%), Positives = 410/880 (46%), Gaps = 160/880 (18%) Query: 246 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 305 G GD G LR + G +P P V P G E + S E +Q Sbjct: 551 GVPGDPG---------LRGQPGRKGLDGIPGTPGVKGLP---GPKGELALSGEKGDQGPP 598 Query: 306 ASLGAQTLPGSDSVSTWDGSVRTPG-GRVKEGGLKGQKGEPGVPGPPGRAGPPG----SP 360 G+ PG G PG G E GL+G +G PG PGPPG AGP G S Sbjct: 599 GDPGSPGSPGPA------GPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652 Query: 361 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGR------DGTPGRDGEPGDPGED- 413 +PGPPG P GP G PGPQGPPG PG G PG DGEPG PG Sbjct: 653 PVPGPPGPP------GPPGH-----PGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF 701 Query: 414 -GKPGDTGPQGFPGT---------------PGDVGPKGDKGDPGVGERGPPGPQGPPGPP 457 G PG G QGFPGT PG G G KG+P V G PG G PG Sbjct: 702 PGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGER 761 Query: 458 GPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPG 517 G S H ++ + G E L GPRG PG PGPPG G PG + +PG Sbjct: 762 GNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPG 821 Query: 518 PAGLPGVPGREG---PPGFPGLPG--PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA 572 GL G GR G P G PG+PG G PG G PG G +G +G G G+ G+ G Sbjct: 822 LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGI 881 Query: 573 PGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGLPAGFDDMEGSGGPFWSTARSA 628 GP G G G+ G PG GPPGPPG PG PG PG+P G G+ G A+ Sbjct: 882 LGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIP-GVKGQRGTPG-----AKGE 935 Query: 629 DGPQGPPG------LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGD 682 G +G PG + G KG+PG+ G G GE G GVPG PGL G +G+ GP GP G Sbjct: 936 QGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGP 995 Query: 683 RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGF---- 737 RG G G+PG+ G+ G PG G G PG S+ L PG GRPG G Sbjct: 996 RGDLGSTGNPGEPGLRGIPGSMGNMGMPG-----SKGKRGTLGFPGRAGRPGLPGIHGLQ 1050 Query: 738 -------------PGPAGPKGN------LGSKGERGSPGPKGE------KGEPGSIFSPD 772 PGP GP G+ +G KGE G PGP G +G PGS SP Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110 Query: 773 -GGALGP-------AQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG 824 G GP KG G PG RGPPG G PG G +G G GR G+ G GEKG Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170 Query: 825 EPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR-----------PGPPGLP 873 E G G RG PG G G G PG P A PGPPGLP Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230 Query: 874 G--------NQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERG 925 G N+GPPG +G+ G GPPGPPG + + G KGD+G G G +G Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPG----------SHVIGIKGDKGSMGHPGPKG 1280 Query: 926 EPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE-SIRGQPGPPGPQGPPGIGYEGRQGPP 984 PG G G PPG G G PG+PGP+G+ +G PG G +G PG + G GPP Sbjct: 1281 PPGTAGDMG-----PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG--FLGSIGPP 1333 Query: 985 GPPGPPGPPSFPGPHR--QTISVPGPPGPPGPPGPPGTMG 1022 GP GP GPP G + IS+PG PGPPG PG PG G Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373 Score = 480 bits (1235), Expect = e-135 Identities = 351/939 (37%), Positives = 415/939 (44%), Gaps = 186/939 (19%) Query: 243 DSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQ 302 D+ GD G+ R G + P +P P + P L G + + E Sbjct: 348 DTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERG 407 Query: 303 TTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCL 362 A PGS + G +PG G + +KG PG G PG G PG P + Sbjct: 408 RP--GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGV 465 Query: 363 PGP---PGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT 419 GP PGL C P P P L +PG G G PGR G G G PG PG G PG Sbjct: 466 DGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGF- 524 Query: 420 GPQGFPGTPGDVGPKGDK-------------GDPGV-GERGPPGPQGPPGPPGPSFRHDK 465 GFPG GD G KG+K GDPG+ G+ G G G PG PG Sbjct: 525 --PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG------- 575 Query: 466 LTFIDMEG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRF---GVNSSDVPGPAGL 521 ++G G G+L AL G +G GPPG PG PG PG G G PG G Sbjct: 576 -----VKGLPGPKGEL-ALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGT 629 Query: 522 PGVPGREGPPG-------------FPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKG 568 GVPG GPPG PG PGPPGPPG GP G G GSLG+ G PG G Sbjct: 630 QGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPG 689 Query: 569 SKGA--------PGPAGARGESGLAGAPGPAGPPGPPGPPGPPG-PGLPAGFDDME---- 615 G PGP G +G+ G G G G PG G PG PG PGLP + Sbjct: 690 PDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMP 749 Query: 616 -GSGGPFWSTARSADGPQGP---PGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGR- 670 G G P + R G G PGLPGL G PG GL G +G+ G G PG G PGR Sbjct: 750 GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809 Query: 671 ----------EGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQ-- 718 G+ G +G +G RG G KGDPG G+ + G PG G PG + E Sbjct: 810 IEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGP 869 Query: 719 --------DGSVLSVPGPEGRPGFAGFP---GPAGPKGNLGS------------KGERGS 755 + +L PG +G G GFP GP GP GN G+ KG+RG+ Sbjct: 870 LGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929 Query: 756 PGPKGEKGEPGSIFSPD--------------GGALGPAQKGAKGEP------GFRGPPGP 795 PG KGE+G+ G+ + G A P +KG +G P G +G PGP Sbjct: 930 PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989 Query: 796 YGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPG-------DASLGF-GMRGMPGPPGPPGP 847 G PG +G++G G PG PG+ G+ G G G +LGF G G PG PG G Sbjct: 990 AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049 Query: 848 PGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQF------PFDF 901 G G P Y +E +RPGPPG G+ G PG G KGE+G PGPPG Sbjct: 1050 QGDKGEPGY-----SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPG 1104 Query: 902 LQLEAEMKGEKGDRGDAGQK---------GERGEPGGGGFFGS-------------SLPG 939 + G+ G GD G K G RG PG GF GS +PG Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG 1164 Query: 940 PPG----------PPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-IGYEGRQGPPGPPG 988 P G PPGPRG PG G KG+ RG PG PG G G +G G +GP G G Sbjct: 1165 PAGEKGETGLLRAPPGPRGNPGAQGAKGD--RGAPGFPGLPGRKGAMGDAGPRGPTGIEG 1222 Query: 989 PPGPPSFPGP-------HRQTISVPGPPGPPGPPGPPGT 1020 PGPP PG +R G PG PGPPGPPG+ Sbjct: 1223 FPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGS 1261 Score = 470 bits (1209), Expect = e-132 Identities = 340/890 (38%), Positives = 403/890 (45%), Gaps = 195/890 (21%) Query: 309 GAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSPCLPGP- 365 G + LPG + G G + G GL G G PG+PG PG GP G +PG Sbjct: 67 GPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCS 126 Query: 366 --------PGLPCPVSPLG-PAGPALQTVPGPQGPP-----------GPPGRDGTPGRDG 405 PGLP LG P P + G +G P G PG G PG G Sbjct: 127 GSKGEQGFPGLP---GTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQG 183 Query: 406 EPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPG---VGERGPPGPQGPPGPPGPSFR 462 PG PG G G GP GF G PG +GP+G KG G +G +G G +G GPPGP Sbjct: 184 LPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGP--- 240 Query: 463 HDKLTFIDMEGSGFGGDLEALRGPRGF---PGPPGP--------------PGVPGLPGEP 505 + + G DL+ +G +G PGPPGP PG PGL G+P Sbjct: 241 -PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKP 299 Query: 506 GRFGV----NSSDVPGPAGLPGVPGRE---------GPPGF---------------PGLP 537 G+ GV S V G G PG+ G + GPPGF G P Sbjct: 300 GKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTP 359 Query: 538 GPPGP-----------------------PGREGPPGRTGQKGSLGEAGAPGHKGSKGAPG 574 GPPGP PG G PG G KGS GE G PG K + G PG Sbjct: 360 GPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGTPG 418 Query: 575 PAGARGESGLAGAPGPAGPP-------GPPGPPGPPG----PGLPAGFDDMEGSGGPFWS 623 G G GL G+PGP GPP GPPG G PG PG+P G D +G G + Sbjct: 419 SPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIP-GVDGPKGEPGLLCT 477 Query: 624 TARSADGPQGPPGLPGLKGDPGVP------GLPGAKGEVGADGVPGFPGLPGREGIAGPQ 677 GP G PGLPGL G G+P GL G+ G G G+PGFPG PG +G G + Sbjct: 478 QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK 537 Query: 678 GPK-------------GDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVL 723 G K GD G RG+ G G DG+ G PG+ G PGP G + E+ Sbjct: 538 GEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ-- 595 Query: 724 SVPGPEGRPGFAGFPGPAGPKGN-----------LGSKGERGSPGPKGEKGEPG--SIFS 770 GP G PG G PGPAGP G G++G G+PGP GE G G S+ + Sbjct: 596 ---GPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652 Query: 771 PDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGL--------KGE 822 P G GP G G PG +GPPG G G G+ G PG G PG+ G+ KG+ Sbjct: 653 PVPGPPGP--PGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGD 710 Query: 823 KGEPG-DASLG----FGMRGMPGPPGPPGP--------PGPPGTPVY-----DSNVFAES 864 +G PG SLG G G+PG PG PG PG PGTP + +S E Sbjct: 711 QGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEI 770 Query: 865 SRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAE--------MKGEKGDRG 916 PG PGLPG G G G +G+ G PGPPG+ +E + G KG +G Sbjct: 771 GLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQG 830 Query: 917 DAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-- 974 G+ G +G+PG G S PG G PG G+ G GP G+ RG PG PG GPPG Sbjct: 831 RRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ--RGYPGNPGILGPPGED 888 Query: 975 --IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1022 IG G G GPPGPPG P PG R + +PG G G PG G G Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGTPG-QRGSPGIPGVKGQRGTPGAKGEQG 937 Score = 454 bits (1168), Expect = e-127 Identities = 322/796 (40%), Positives = 364/796 (45%), Gaps = 144/796 (18%) Query: 337 GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP-ALQTVPGPQGPPGPP 395 G KG+KGE G PGPPG PG G P GP GP +PG G G Sbjct: 43 GAKGEKGEKGFPGPPGS---------PGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVR 93 Query: 396 GRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPP 454 G G PG G PG P G PG+TGP G G PG G KG++G PG+ G G PG G Sbjct: 94 GISGLPGFSGSPGLP---GTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAA 150 Query: 455 GPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSD 514 G G K I+++ G G L GP+G PGPPG PG G PG PG FG + Sbjct: 151 GLKGQKGAPAKEEDIELDAKGDPG-LPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM 209 Query: 515 VP-GPAGLPG--VPGREGPPGFPGLPGPPGPPGR-----EGPPGRT---GQKGSLGEAGA 563 P GP G G V G +G G GL GPPGPPG GP RT G+KG G G Sbjct: 210 GPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE 269 Query: 564 PGHKGSKGAPGPA-----GARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSG 618 PG G G PG + GA G+ GL G PG G PG PG G G GF + G Sbjct: 270 PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG---NRGFPGLMGED 326 Query: 619 GPFWSTARSADGPQGPPGLPG---------LKGDPGVPGLP---GAKGEVGADGVPGFPG 666 G + G GPPG G KGD G PG P GA+G G G PG PG Sbjct: 327 G-----IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPG 381 Query: 667 LPG--REGIAGPQGPKGDRGSRGEKGDPGKDGVGQ------------PGLPGPPGPPGPV 712 PG R G+ G G G +GS+GE+G PGKD +G PG PGPPGPPG + Sbjct: 382 SPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDI 441 Query: 713 VYVSEQDG----------------------------SVLSVPGPEGRPGFAGFPGPAGPK 744 V+ G +PGP G PG G G G Sbjct: 442 VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIP 501 Query: 745 GNLGSKGERGSPGPKGEKGEPGSIFSPDGGALG-PAQKGAKGEP-------GFRGPPGPY 796 G G+ G +GSPG G G PG F GA G P KG KGE G G PG Sbjct: 502 GRQGAAGLKGSPGSPGNTGLPG--FPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLR 559 Query: 797 GRPGYKGEIGFPGRPGRPGMNGLKGE---KGEPGDASLGFGMRGMPGPPGPPGPPGPPGT 853 G+PG KG G PG PG G+ G KGE GE GD G G PG PG PGP GP G Sbjct: 560 GQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ----GPPGDPGSPGSPGPAGPAGP 615 Query: 854 PVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEV-------GPPGPPGQFPFDFLQLEA 906 P Y E G G+PG GPPG G +GE+ GPPGPPG Q Sbjct: 616 PGYGPQ--GEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPP 673 Query: 907 EMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYP------GIPGPKGE-S 959 + G G GD G G GEP G G PGPPGP G +G+P G PG GE Sbjct: 674 GIPGSLGKCGDPGLPGPDGEP---GIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPG 730 Query: 960 IRGQPGPPGPQGPPGIGYEGRQGPPGPPGP------------PGPPSFPG-PHRQTISVP 1006 + G+PG PG +G P + G G PG PG PG P PG P + + Sbjct: 731 LPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNE--GLD 788 Query: 1007 GPPGPPGPPGPPGTMG 1022 GP G PG PGPPG G Sbjct: 789 GPRGDPGQPGPPGEQG 804 Score = 404 bits (1038), Expect = e-112 Identities = 289/717 (40%), Positives = 332/717 (46%), Gaps = 161/717 (22%) Query: 436 DKG----DPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPG 491 DKG D GE+G G GPPG PG GF GP G PG Sbjct: 35 DKGQCFCDGAKGEKGEKGFPGPPGSPGQK--------------GF-------TGPEGLPG 73 Query: 492 PPGPPGVPGLPGEPGRFGVNS-SDVPG---PAGLPGVPGREGPPGFPGLPGPPGPPGREG 547 P GP G PGLPG G GV S +PG GLPG PG GP G G+PG G G +G Sbjct: 74 PQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQG 133 Query: 548 PPGRTGQKGSLGEAGAPGHKGSKGAPGPA-----GARGESGLAGAPGPAGPPGPPGPPGP 602 PG G G G GA G KG KGAP A+G+ GL GAPGP G PGPPG PGP Sbjct: 134 FPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGP 193 Query: 603 PGPGLPAGFDDMEGSGGPFWSTARSAD---------------GPQGPPG----------- 636 GP P GF G+ GP + GP GPPG Sbjct: 194 VGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDN 253 Query: 637 ---LPGLKGDPGVPGLPGAKG-----------EVGADGVPGFPGLPGREGIAGPQGPKGD 682 L G KGD G G PG G E GA G PG G PG++G+ G G +G Sbjct: 254 RTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGV 313 Query: 683 RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSE-QDGSVLSVPGPEGRPGFAGFPGP 740 +G+RG G G+DG+ GQ G GPPG GP Y Q+ PGP G G G GP Sbjct: 314 KGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGP 373 Query: 741 AGPKGNLGSKGE-----RGSPGPKGEKGEPGSIFSPDGGALG----PAQKGAKGEPGFRG 791 +GP G GS G RG+PG G KG G P A+G P G+ G PG G Sbjct: 374 SGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPG 433 Query: 792 PPGPYG----RPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLG--------------- 832 PPGP G R G G+ G PG G PG+ G+ G KGEPG Sbjct: 434 PPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493 Query: 833 -FGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE---- 887 G++G+PG G G G PG+P + PG PG PG QG PG KG KGE Sbjct: 494 LHGVKGIPGRQGAAGLKGSPGSP-------GNTGLPGFPGFPGAQGDPGLKGEKGETLQP 546 Query: 888 ---VGPPGPPG------QFPFDFLQLEAEMKGEKGDRGD---AGQKGERGEPGGGGFFGS 935 VG PG PG + D + +KG G +G+ +G+KG++G PG G GS Sbjct: 547 EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606 Query: 936 SLPGPPGPPGPRGY--------------PGIPGPKGES-IRGQ-------PGPPGPQGPP 973 PGP GP GP GY PG PGP GE+ RG+ PGPPGP GPP Sbjct: 607 --PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664 Query: 974 GIGYEGRQGPPGPP---GPPGPPSFPGPHRQT----ISVPGPPGPPGPPGPPGTMGA 1023 G + G QGPPG P G G P PGP + I PGPPGP G G PGT G+ Sbjct: 665 G--HPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719 Score = 385 bits (990), Expect = e-106 Identities = 274/701 (39%), Positives = 309/701 (44%), Gaps = 147/701 (20%) Query: 272 PRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGG 331 P P PP PP G E R GAQ LPG + + G G Sbjct: 794 PGQPGPPGEQGPP---GRCIEGPR-------------GAQGLPGLNGLKGQQGRRGKTGP 837 Query: 332 RVKEG-------GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQT 384 + G G G+ G PG+PG G GP G PG PG+ P G G + Sbjct: 838 KGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIG--MMG 895 Query: 385 VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPK------GDKG 438 PG GPPGPPG GTPG+ G PG PG G+ G G +G G G+ GP GDKG Sbjct: 896 FPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKG 955 Query: 439 DPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP----- 492 +PG+ G G PG +G G PG G G L+ L GP G PGP Sbjct: 956 EPGLKGFAGNPGEKGNRGVPGMP--------------GLKG-LKGLPGPAGPPGPRGDLG 1000 Query: 493 ----PGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGL------------ 536 PG PG+ G+PG G G+ S G G G PGR G PG PG+ Sbjct: 1001 STGNPGEPGLRGIPGSMGNMGMPGSK--GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGY 1058 Query: 537 -----PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGP- 590 PGPPGP G G PG G+KG +G+ G PGH G G G G+ G GL G PGP Sbjct: 1059 SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPH 1118 Query: 591 -----------AGPPGPPGPPGPPG-PGLPA--------GFDDMEGSGGPFWSTA--RSA 628 GPPG GPPG PG PG P G D + G G T R+ Sbjct: 1119 GDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAP 1178 Query: 629 DGPQGPPGLPGLKGD---PGVPGLPGAKGEVG---------ADGVPGFPGLPGR--EGIA 674 GP+G PG G KGD PG PGLPG KG +G +G PG PGLPG G Sbjct: 1179 PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT 1238 Query: 675 GPQGPKGDRGSRGEKGDPGKDGV---------GQPGLPGPPGPPGPVVYVSEQDG----S 721 G +GP G RGS G G PG G G G PGP GPPG + Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPG 1298 Query: 722 VLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGAL----- 776 +PGP G PGF GFPG G KGN G G G PGP G KG PG D G L Sbjct: 1299 TPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG--VRGDPGTLKIISL 1356 Query: 777 --GPAQKGAKGEPGFRGPPGPYGRPGY---------KGEIGFPGRPGRPGMNGLKGEKGE 825 P G GEPG +G PGP G PG G+ G PG PG G G KG KGE Sbjct: 1357 PGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGE 1416 Query: 826 PGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR 866 PG A G G+PG G G G P T VF S+ Sbjct: 1417 PGPA----GSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQ 1453 Score = 338 bits (868), Expect = 2e-92 Identities = 242/644 (37%), Positives = 286/644 (44%), Gaps = 119/644 (18%) Query: 241 GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 300 G D G G++GS + E G + P P + PP G + Sbjct: 845 GLDRSGFPGETGSPGIPGHQ---GEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIG 901 Query: 301 EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGG-----------LKGQKGEPGV-- 347 + G GS + G TPG + ++G + G KGEPG+ Sbjct: 902 PPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKG 961 Query: 348 ----PGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG----------PALQTVPGPQGPPG 393 PG G G PG P L G GLP P P GP G P L+ +PG G G Sbjct: 962 FAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMG 1021 Query: 394 PPGRDGT------PGRDGEPGDPGEDG--------------KPGDTGPQGFPGTPGDVGP 433 PG G PGR G PG PG G +PG GP G PG PGD+G Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGK 1081 Query: 434 KGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP 492 KG+ G PG G GP GP+G PG PG K G GDL +G +G GP Sbjct: 1082 KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK--------PGPHGDL-GFKGIKGLLGP 1132 Query: 493 PG---PPGVPGLPGEPGRFGVNSSD----VPGPAGLPGVPGR----EGPPGFPGLPGPPG 541 PG PPG+PG PG PG G+ +PGPAG G G GP G PG G G Sbjct: 1133 PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKG 1192 Query: 542 PPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARG-----ESGLAGAPGPAGPPGP 596 G G PG G+KG++G+AG G G +G PGP G G ++G G PG G PG Sbjct: 1193 DRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGA 1252 Query: 597 PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGL------PGLKGDPGVPGLP 650 PGPPGPPG + D G P GP+GPPG PG G PG PGLP Sbjct: 1253 PGPPGPPGSHVIGIKGDKGSMGHP---------GPKGPPGTAGDMGPPGRLGAPGTPGLP 1303 Query: 651 GAKGEVGADGVPGFPGL---PGREGIAGPQGPKGDRGSRGEKGDPGK-DGVGQPGLPGPP 706 G +G+ G G PG G PG G GP GP G +G G +GDPG + PG PGPP Sbjct: 1304 GPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPP 1363 Query: 707 GPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPG---PAGPKGNLGSKGERGSPGPKGEKG 763 G PG PG +G PG G PG P GP+G G G+ G+PGP GEKG Sbjct: 1364 GTPGE--------------PGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409 Query: 764 EPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGF 807 GS P GPA G+ G PG +G G G P GF Sbjct: 1410 NKGSKGEP-----GPA--GSDGLPGLKGKRGDSGSPATWTTRGF 1446 Score = 276 bits (706), Expect = 1e-73 Identities = 201/508 (39%), Positives = 230/508 (45%), Gaps = 106/508 (20%) Query: 567 KGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTAR 626 KG G G +GE G G PG G G GP G PGP P GF + G G Sbjct: 36 KGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTG------- 88 Query: 627 SADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPG---------FPGLP---GREGIA 674 + G +G GLPG G PG+PG PG G G GVPG FPGLP G GI Sbjct: 89 -SKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIP 147 Query: 675 GPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGF 734 G G KG +G+ ++ D D G PGLPG PGP+G PG Sbjct: 148 GAAGLKGQKGAPAKEEDIELDAKGDPGLPG--------------------APGPQGLPGP 187 Query: 735 AGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPG 794 GFPGP GP G G G G+ GP+G KG G +G KG +G G GPPG Sbjct: 188 PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGE------RVIG--HKGERGVKGLTGPPG 239 Query: 795 PYGR--------------PGYKGEIGFPGRPGRPGMNGLKGE-----KGEPGDASLGFGM 835 P G G KG+ G G PG PG +GL GE KG PGD G+ Sbjct: 240 PPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDP----GL 295 Query: 836 RGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPG 895 +G PG G PG PG G G G PG G G KG KG++GPPG G Sbjct: 296 QGKPGKDGVPGFPGSEGVK-------------GNRGFPGLMGEDGIKGQKGDIGPPGFRG 342 Query: 896 QFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGP--PGPRGYPGIP 953 P ++ E KG++G G G +G RG G G G +PG PG PG RG PG P Sbjct: 343 --PTEYYDTYQE-KGDEGTPGPPGPRGARGPQGPSGPPG--VPGSPGSSRPGLRGAPGWP 397 Query: 954 GPKG-ESIRGQPGPP--GPQGPPGI-GYEGRQGPPGPPGPPGPPSF----PGPHRQTISV 1005 G KG + RG+PG G G PG G G G PGPPGPPG F PG H Sbjct: 398 GLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH------ 451 Query: 1006 PGPPGPPGPPGPPGTMGASSGVRLWATR 1033 G PG G PG PG G L T+ Sbjct: 452 -GLPGYLGSPGIPGVDGPKGEPGLLCTQ 478 Score = 168 bits (426), Expect = 3e-41 Identities = 118/312 (37%), Positives = 134/312 (42%), Gaps = 72/312 (23%) Query: 766 GSIFSPDGGALGPAQKGAKGEPGFRGPP---------GPYGRPGYKGEIGFPGRPGRPGM 816 G + G KG KGE GF GPP GP G PG +G GFPG PG G Sbjct: 30 GCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGS 89 Query: 817 NGLKGEKGEPGDASLGFGMRGMPGPPGPPGP------------------PGPPGT----- 853 G++G G PG + G G+PG PG GP PG PGT Sbjct: 90 KGVRGISGLPGFS----GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145 Query: 854 -------------PVYDSNVFAES-SRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPF 899 P + ++ ++ PG PG PG QG PGP G G VGPPGPPG F F Sbjct: 146 IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205 Query: 900 DFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPP--------GPRGYPG 951 KG G+R G KGERG G L GPPGPP GP Sbjct: 206 PGAMGPRGPKGHMGER-VIGHKGERGVKG--------LTGPPGPPGTVIVTLTGPDNRTD 256 Query: 952 IPGPKGE-SIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPG 1010 + G KG+ G+PGPPGP G PG Y +G PG PG G P G PG G Sbjct: 257 LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDG----VPGFPGSEG 312 Query: 1011 PPGPPGPPGTMG 1022 G G PG MG Sbjct: 313 VKGNRGFPGLMG 324 >gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] Length = 1073 Score = 504 bits (1297), Expect = e-142 Identities = 337/832 (40%), Positives = 383/832 (46%), Gaps = 134/832 (16%) Query: 288 GSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGV 347 G ED + + + G PG + G+ PG R ++G +G+KGE G+ Sbjct: 253 GERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGD-QGEKGELGL 311 Query: 348 PG------PPGRAGPPGSPCLPGP-------PGLPCPVSPLG-------PAGPALQTVPG 387 PG G AGP G P LPG P +P P G P P LQ PG Sbjct: 312 PGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPG 371 Query: 388 ---PQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-- 442 PQGP GPPG G G G PG G G PG G G G PG VG G +G PG Sbjct: 372 ELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDG 431 Query: 443 --GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP------PG 494 GE+G G +G PGP GP G G G+ LRG G PGP G Sbjct: 432 ERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGE-PGLRGSPGLPGPLGTKGDRG 490 Query: 495 PPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREG-----PP 549 PG+PG PG G G+ + PGP+G PG G G G PG PGP GP GR+G P Sbjct: 491 APGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSP 550 Query: 550 GRTG----------QKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGP 599 G G G G PG KG KG PG G G G G GP G PGPPG Sbjct: 551 GDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGI 610 Query: 600 PGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGAD 659 GP G G D G G QG PG+PG G PG PG PGA G GA Sbjct: 611 AGPQGSQGERGADGEVGQ-----------KGDQGHPGVPGFMGPPGNPGPPGADGIAGAA 659 Query: 660 GVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG----------VGQPGLPGPPGPP 709 G PG G PG+EG GPQGP G G GE+G G+DG G+PGLPGP G Sbjct: 660 GPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGAR 719 Query: 710 GPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIF 769 GP + S PGP G G G PG G G G G G GP+G +G PG Sbjct: 720 GPPGFKGHTGDS--GAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNG 777 Query: 770 SPD-----GGALGPAQKGAKGE------PGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNG 818 SP G + P QKG+KGE PGF GP GP G PG KG G G PG+PG G Sbjct: 778 SPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPG 837 Query: 819 LKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGP 878 KGE+G+PG ++G GPPG G PG PG P + + + GP GLPG GP Sbjct: 838 FKGERGDPG-------IKGDKGPPGGKGQPGDPGIPGHKGH----TGLMGPQGLPGENGP 886 Query: 879 PGPKGAKGEVGPPGPPGQFP-FDFL----------QLE------------AEMKGEKGDR 915 GP G G+ G PG G+ P + L QLE A MK +G Sbjct: 887 VGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRP 946 Query: 916 GDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI 975 G G G+ G PG G G PG PG G G G GPKGE RG G PG PG+ Sbjct: 947 GPPGPPGKDGLPGRAGPMGE--PGRPGQGGLEGPSGPIGPKGE--RGAKGDPGA---PGV 999 Query: 976 GYEGRQGPPGPPGPPGPPSF--------PGPHRQTISVPGPPGPPGPPGPPG 1019 G G GPPG PG PG P + PGP +T G PG PGPPGPPG Sbjct: 1000 GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGET-GPAGHPGLPGPPGPPG 1050 Score = 497 bits (1280), Expect = e-140 Identities = 326/790 (41%), Positives = 378/790 (47%), Gaps = 122/790 (15%) Query: 325 SVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG-PALQ 383 + +T G + G G++GE G+PG PG G G L G PG G AG P Sbjct: 238 AAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPG------EKGEAGLPGAP 291 Query: 384 TVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGT----------PGDVGP 433 PG +G G G G G G GD GE G+ G GP G PGT PG+ GP Sbjct: 292 GFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGP 351 Query: 434 KGDKGDPGV----------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEAL 483 KG+KGDPG+ GE GP GP GPPG G H G G+ A Sbjct: 352 KGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHG--------APGAAGNPGA- 402 Query: 484 RGPRGFPGPPGPPG---VPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP 540 G G PGP GPPG PGL G PG+ G G AG G PG GP G PG PG P Sbjct: 403 PGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEK--GAAGEEGSPGPVGPRGDPGAPGLP 460 Query: 541 GPPGR--EGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGL--AGAPGPAGPPGP 596 GPPG+ +G PG G G G G G +G+ G PG G+RG+ G+ AG PGP+GPPG Sbjct: 461 GPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGD 520 Query: 597 PGPPGP------PGPGLPAGFDDMEGSGGPFWSTARSAD-------GPQGPPGLPGLKGD 643 G PG PGP PAG D + P + D GP G PGLPG KGD Sbjct: 521 KGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGD 580 Query: 644 PGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGL 702 GVPG PG +G G G G PGLPG GIAGPQG +G+RG+ GE G G G G PG Sbjct: 581 KGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGF 640 Query: 703 PGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEK 762 GPPG PGP ++ PG +G PG G PGP GP G G GE G G G+ Sbjct: 641 MGPPGNPGPPG--ADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKP 698 Query: 763 GEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGE 822 G PG L P +GA+G PGF+G G G PG +GE G G PG+ G+ G G+ Sbjct: 699 GPPGEPGKAGEPGL-PGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGD 757 Query: 823 KGEPGDASLGFGMRGMPGP---PGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPP 879 G G G RG PG PG PG PGP GTP + E+ PG PG G +GPP Sbjct: 758 TGPTGPQGPQ-GPRGPPGKNGSPGSPGEPGPSGTPGQKGSK-GENGSPGLPGFLGPRGPP 815 Query: 880 GP---KGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSS 936 G KG G+ G PG PG+ F + + +KG+KG G GQ G+ G PG G G Sbjct: 816 GEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLM 875 Query: 937 LP-------GPPGPPGPRGYPGIPGPKGES------------------------------ 959 P GP GPPGP G PG PG +GES Sbjct: 876 GPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMP 935 Query: 960 ------IRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPG 1013 +G+PGPPGP G G+ GR GP G PG PG GP GP GP G Sbjct: 936 PAYMKSSQGRPGPPGPPGKDGL--PGRAGPMGEPGRPGQGGLEGPS-------GPIGPKG 986 Query: 1014 PPGPPGTMGA 1023 G G GA Sbjct: 987 ERGAKGDPGA 996 Score = 471 bits (1211), Expect = e-132 Identities = 323/799 (40%), Positives = 363/799 (45%), Gaps = 154/799 (19%) Query: 246 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 305 G GD G L E G +P P T PP A G Sbjct: 353 GEKGDPG---------LPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPG------AA 397 Query: 306 ASLGAQTLPGSDSVSTWDGSVRTPG-----GRVKEGGLKGQKGEPGVPGPPGRAGPPGSP 360 + GA G+ S GSV PG G+ E G KG GE G PGP G G PG+P Sbjct: 398 GNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAP 457 Query: 361 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG 420 LPGPPG G G PG +G PG PG GT G G PG PG G GD G Sbjct: 458 GLPGPPGK-------GKDGE-----PGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPG 505 Query: 421 PQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDL 480 G G PG GP GDKG P G RG PG GP GP G L+ GD+ Sbjct: 506 -IGVAGPPGPSGPPGDKGSP--GSRGLPGFPGPQGPAGRDGLSSLLS---------PGDI 553 Query: 481 EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLP--- 537 L PPGPPG+PGLPG G GV PG G G G GPPG PG P Sbjct: 554 NLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGK--PGREGTEGKKGEAGPPGLPGPPGIA 611 Query: 538 GPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPP 597 GP G G G G GQKG G G PG G G PGP GA G +G AG PG G PG Sbjct: 612 GPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKE 671 Query: 598 GPPGPPGP-GLPA-----GFDDMEGSGGPFWSTARSAD----GPQGPPGLPGLKGDPGVP 647 GPPGP GP GLP G + +G GP ++ + GP+G G PG KG G Sbjct: 672 GPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDS 731 Query: 648 GLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPP 706 G PG +GE GA G+PG GLPG++G GP GP+G +G R G PGK+G G PG PGP Sbjct: 732 GAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPR---GPPGKNGSPGSPGEPGPS 788 Query: 707 GPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPG 766 G PG Q GS G G PG GF GP GP G G KG G G G+ GEPG Sbjct: 789 GTPG-------QKGS----KGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPG 837 Query: 767 SIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEP 826 KG +G+PG +G GP PG KG+ G PG PG G GL G +G P Sbjct: 838 F-------------KGERGDPGIKGDKGP---PGGKGQPGDPGIPGHKGHTGLMGPQGLP 881 Query: 827 GDASLGFGMRGMPGPPGPPGPPGPPG---------------------------------- 852 G+ G GPPGPPG PG PG Sbjct: 882 GE-------NGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQM 934 Query: 853 TPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEK 912 P Y + + RPGPPG PG G PG G GE G PG G ++G Sbjct: 935 PPAY---MKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGG------------LEGPS 979 Query: 913 GDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGP 972 G G G++G +G+PG G L G GPPG G PG PG + + G PGP G GP Sbjct: 980 GPIGPKGERGAKGDPGAPGV---GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGP 1036 Query: 973 PGIGYEGRQGPPGPPGPPG 991 G G PGPPGPPG Sbjct: 1037 -----AGHPGLPGPPGPPG 1050 Score = 447 bits (1151), Expect = e-125 Identities = 302/771 (39%), Positives = 356/771 (46%), Gaps = 154/771 (19%) Query: 349 GPPGRAGPPGSPCLPGPPGLPCPV---------SPLGPAGPALQ-------------TVP 386 G G G + LP C + + LG GPA Q T P Sbjct: 184 GAQGACGRGNTSVLPSSVAPQCSMPKGTGHEFSAALGTQGPADQRADARASCILAAKTAP 243 Query: 387 GPQ---GPPGPPGRDGTPGRDGEPGDPGEDG---KPGDTGPQGFPGTPGDVGPKGDKGDP 440 G + G PG G DG PG+ G G+ GE G +PG+ G G PG PG G +G+KGD Sbjct: 244 GLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQ 303 Query: 441 GV-------------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPR 487 G GE+G GP GPPG PG T + G+ +GP+ Sbjct: 304 GEKGELGLPGLKGDRGEKGEAGPAGPPGLPGT-------TSLFTPHPRMPGE----QGPK 352 Query: 488 GFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREG 547 G G PG PG PGL G PG G GP G PG G+EG G PG G PG PG G Sbjct: 353 GEKGDPGLPGEPGLQGRPGELGPQ-----GPTGPPGAKGQEGAHGAPGAAGNPGAPGHVG 407 Query: 548 PPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGL 607 PG +G GS+G APG +G+ G G G +G +G G+PGP GP G PG PG PGP Sbjct: 408 APGPSGPPGSVG---APGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPP- 463 Query: 608 PAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGL 667 +G G PGL+G PG+PG G KG+ GA G+PG PG Sbjct: 464 -----------------------GKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGS 500 Query: 668 PGREGIA-----GPQGPKGDRGSRGEKGDPGKDG----VGQPGL-----PG--------- 704 G GI GP GP GD+GS G +G PG G G+ GL PG Sbjct: 501 RGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDV 560 Query: 705 ----PPGPPG-PVVYVSEQDGSVLSVPGPEGR---------PGFAGFPGPAGPKGNLGSK 750 PPGPPG P + + D V PG EG PG G PG AGP+G+ G + Sbjct: 561 CNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGER 620 Query: 751 GERGSPGPKGEKGEPG--SIFSPDGGALGPAQ---KGAKGEPGFRGPPGPYGRPGYKGEI 805 G G G KG++G PG P G P GA G PG +G PG G PG +G Sbjct: 621 GADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPS 680 Query: 806 GFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESS 865 G PG PG G G G+ G PG+ G G PG PGP G GPPG + + A Sbjct: 681 GLPGIPGEEGKEGRDGKPGPPGEP----GKAGEPGLPGPEGARGPPGFKGHTGDSGAPGP 736 Query: 866 R--------PGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGD 917 R PG GLPG G GP G +G GP GPPG+ GE G G Sbjct: 737 RGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGK------NGSPGSPGEPGPSGT 790 Query: 918 AGQKGERGEPGGGGFFGSSLP-GPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIG 976 GQKG +GE G G G P GPPG PG +G PG G G+ G+PG G +G PGI Sbjct: 791 PGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKP--GEPGFKGERGDPGI- 847 Query: 977 YEGRQGPPGPPGPPGPPSFPGPHRQT-----ISVPGPPGPPGPPGPPGTMG 1022 +G +GPPG G PG P PG T +PG GP GPPGPPG G Sbjct: 848 -KGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPG 897 Score = 329 bits (844), Expect = 9e-90 Identities = 212/505 (41%), Positives = 241/505 (47%), Gaps = 76/505 (15%) Query: 314 PGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGP--------------- 356 PG + + G PG +EG G KG+ G PG+PGPPG AGP Sbjct: 569 PGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQ 628 Query: 357 ------PGSPCLPGPPGLPCPVSPLGPAG----PALQTVPGPQGPPGPPGRDGTPGRDGE 406 PG P GPPG P P G AG P +Q PG +GPPGP G G PG GE Sbjct: 629 KGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGE 688 Query: 407 PGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKL 466 G G DGKPG G G G PG GP+G +G PG +G G G PGP G S + Sbjct: 689 EGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGF--KGHTGDSGAPGPRGES---GAM 743 Query: 467 TFIDMEG-SGFGGDLEAL--RGPRGFPGPPGPPGVPGLPGEPGRFGV-NSSDVPGPAGLP 522 EG G GD +GP+G GPPG G PG PGEPG G G G P Sbjct: 744 GLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSP 803 Query: 523 GVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGES 582 G+PG GP G PG PG G PG+EG PG+ G+ G GE G PG KG KG PG G G+ Sbjct: 804 GLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDP 863 Query: 583 GL------------AGAPGPAGPPGPPGPPGPPG-PGLPAGFDDME-------GSGGPFW 622 G+ G PG GP GPPGPPG PG PGL ME G Sbjct: 864 GIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQL 923 Query: 623 STARSADGPQGPPG-LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKG 681 T + Q PP + +G PG PG PG G G G G PG PG+ G+ GP GP G Sbjct: 924 ETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIG 983 Query: 682 DRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFA--GFPG 739 +G RG KGDPG GVG G GPPG +PG G PG+A G PG Sbjct: 984 PKGERGAKGDPGAPGVGLRGEMGPPG-----------------IPGQPGEPGYAKDGLPG 1026 Query: 740 PAGPKGNLGSKGERGSPGPKGEKGE 764 GP+G G G G PGP G G+ Sbjct: 1027 IPGPQGETGPAGHPGLPGPPGPPGQ 1051 Score = 249 bits (635), Expect = 2e-65 Identities = 181/534 (33%), Positives = 219/534 (41%), Gaps = 139/534 (26%) Query: 246 GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTT- 304 G GD G RE + G A P LP PP + P + G D + +Q Sbjct: 576 GFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHP 635 Query: 305 -----VASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAG-- 355 + G PG+D ++ G G KEG G +G G PG+PG G+ G Sbjct: 636 GVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRD 695 Query: 356 ----PPGSPCLPGPPGLPCPVSPLGPAG----------------------PALQTVPG-- 387 PPG P G PGLP P GP G P + +PG Sbjct: 696 GKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKD 755 Query: 388 ----------PQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDK 437 PQGP GPPG++G+PG GEPG G G+ G G G PG PG +GP+G Sbjct: 756 GDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPP 815 Query: 438 GDPGVGERGPPGPQGPPGPPG-PSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPP 496 G+PG E+G PG +G PG PG P F+ ++ GD ++G +G PG G P Sbjct: 816 GEPG--EKGVPGKEGVPGKPGEPGFKGER------------GD-PGIKGDKGPPGGKGQP 860 Query: 497 GVPGLPGEPGRFGV-NSSDVPGPAGLPGVPGREGPPGFPGL------------------- 536 G PG+PG G G+ +PG G G PG G PGFPGL Sbjct: 861 GDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELG 920 Query: 537 -------------------------PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKG 571 PGPPGPPG++G PGR G G G G G +G G Sbjct: 921 KQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSG 980 Query: 572 APGPAGARGESGLAGAPGPA-----GPPGPPGPPGPPG---PGLPAGFDDMEGSGGPFWS 623 GP G RG G GAPG GPPG PG PG PG GLP Sbjct: 981 PIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLP--------------- 1025 Query: 624 TARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREG-IAGP 676 G GP G G G PG+PG PG G+ F L R G + GP Sbjct: 1026 ------GIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKGP 1073 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 504 bits (1297), Expect = e-142 Identities = 377/1049 (35%), Positives = 439/1049 (41%), Gaps = 280/1049 (26%) Query: 231 VSPMHCLDEEGDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSS 290 V P E+GD DGA G G + G+ + PP P G Sbjct: 1438 VGPPGKKGEKGDSEDGAPGLPG------------QPGSPGEQGPRGPPGAIGPKGDRGFP 1485 Query: 291 TEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPG--GRVKEGGLKGQKGEPGVP 348 + E E+ G++ LPG G PG GR E G G+ G+P V Sbjct: 1486 GPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVV 1545 Query: 349 GP----------------------------------PGRAGPPGSPCLPGPPGLPCPVSP 374 GP PG GP G P GP GL P Sbjct: 1546 GPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGP 1605 Query: 375 LGPAGPALQTV----PGPQGPPGPPGRDGTPGRDGE---PGDPGEDGKPGDTGPQGFPGT 427 G +GP + PGP GP GP GRDG G G+ PGDPG GK G+ G +G PG Sbjct: 1606 PGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGV 1665 Query: 428 PGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDL 480 G VG KGD+GDPG G GP G +G PGPPGP R + +G G Sbjct: 1666 RGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGR--------LVDTGPGARE 1717 Query: 481 EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNS-SDVPGPAGLPGV--------------- 524 + G RG GP GP G PGLPG PG G+ PGP G PGV Sbjct: 1718 KGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGL 1777 Query: 525 ---------------------------PGREGPPGF---PGLPGPPGPPGREGPPGRTGQ 554 PGR+G PG GLPGP GPPG G PG G+ Sbjct: 1778 DGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGK 1837 Query: 555 ---KGSLGEAGAPGHKGSKGAPGPAGA---------RGESGLAGAPGPAGPPGPPGPPGP 602 G GE G PG G KG G +GA +GE G G GP GPPG PGP GP Sbjct: 1838 PGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGP 1897 Query: 603 PG---PGLPAG------------------------------------------------- 610 PG PG+P G Sbjct: 1898 PGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALR 1957 Query: 611 --FDDMEGSGGPFWSTARSADGP------QGPPGLPGLKGDPGVPGLPGAKGEVGADGVP 662 + + S G F GP QGPPG G G PG GL G +G+ G G P Sbjct: 1958 EIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPP 2017 Query: 663 ----------------------GFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG---- 696 G PGLPGR G G G G+RG RGEKG+ G+ G Sbjct: 2018 GLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGP 2077 Query: 697 VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGP------EGRPGFAGFPGPAGPKGNLGSK 750 G PG PGPPGPPGP V V E + GP +G PG G GP G +G G K Sbjct: 2078 PGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIK 2137 Query: 751 GERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGP---YGRPGYKGEIGF 807 G+RG PGP+G+ G PG + G GP +G G G RGPPGP +G PG G G Sbjct: 2138 GDRGEPGPRGQDGNPG--LPGERGMAGP--EGKPGLQGPRGPPGPVGGHGDPGPPGAPGL 2193 Query: 808 PGRPGRPGMNGLKGEKGEPGDASLGF----GMRGMPGPPGPPGPPGPPGTPVYDSNVFAE 863 G G G +GLKGE GE G G G G+PGPPGP G GP G+P V E Sbjct: 2194 AGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQV-GE 2252 Query: 864 SSRP---------------GPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFL------ 902 + +P G PG+PG+ G PGP G KGE GP G PGQ Sbjct: 2253 TGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEK 2312 Query: 903 ----QLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE 958 L ++ GE G +GD G G RGE G G G PG PG G +G PG G KG+ Sbjct: 2313 GAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGE--PGDPGEDGQKGAPGPKGFKGD 2370 Query: 959 SIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGP--HRQTISVPGP-------- 1008 G PG PGP GPPG+ +G G PG PG PG FPG R + PGP Sbjct: 2371 PGVGVPGSPGPPGPPGV--KGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAG 2428 Query: 1009 -------PGPPGPPGPPGTMG--ASSGVR 1028 PGP GPPGPPG++G +SG++ Sbjct: 2429 PPGREGIPGPLGPPGPPGSVGPPGASGLK 2457 Score = 495 bits (1274), Expect = e-139 Identities = 364/988 (36%), Positives = 429/988 (43%), Gaps = 220/988 (22%) Query: 229 PQVSPMHCLDEEGDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGG 288 P+ P++C G G+ G +G LR + G P LP P G Sbjct: 1244 PEPCPVYC-------PKGQKGEPGE-MG-----LRGQVGPPGDPGLPGRTGAPGPQGPPG 1290 Query: 289 SSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPG 346 S+T S G PG+ GS PG R G G +G KGEPG Sbjct: 1291 SATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPG 1350 Query: 347 VPGP---------PGRAGPP------------GSPCLPGPPGLPCP-------------- 371 PG PGR G P G P GPPGLP Sbjct: 1351 APGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGP 1410 Query: 372 -------VSPLGPAGPALQTVPGPQGPPGPPGRDGTPG--RDGEPGDPGEDGKPGDTGPQ 422 ++P P P L PGPQGP GPPG+ G G DG PG PG+ G PG+ GP+ Sbjct: 1411 PGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPR 1470 Query: 423 GFPGTPGDVGPKGDKGDPG-------VGERGPPGP---------------QGPPGPPGPS 460 G PG +GPKGD+G PG GERGPPGP +GP GPPGP+ Sbjct: 1471 ---GPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPT 1527 Query: 461 FRHDKLTFIDMEG--SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGP 518 R + G + G + +G +G GP GP G G+ GE G G+ PGP Sbjct: 1528 GRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGP 1587 Query: 519 AGLP------GVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA 572 G P G+ GR GPPG G PG G PGR GPPG G +G GE G G +G G Sbjct: 1588 KGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGD 1647 Query: 573 PGPAGARGESGLAGAP---------------------------GPAGPPGPPGPPGPPGP 605 PG G GE GL GAP GP G G PGPPGPPG Sbjct: 1648 PGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGR 1707 Query: 606 GLPAGFDDMEGSGGPFWSTARSADGPQGPPGLP---------GLKGDPGVPGLPGAKGEV 656 + G E G P GP+G PGLP G +G PG G PG +G Sbjct: 1708 LVDTGPGARE-KGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPA 1766 Query: 657 GADGVPGFPGLPGREGI---AGPQGPKGDRGSRGEKGDPGKDGV----GQPGLPGPPGPP 709 G G G PGL GR G+ G GP G G+ G+ GDPG+DG+ G+ GLPGP GPP Sbjct: 1767 GEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPP 1826 Query: 710 GPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIF 769 G + +DG + G G PG G G G KG+ G+ G G GPKGE+G PG I Sbjct: 1827 G-LPGKPGEDGKP-GLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPG-IL 1883 Query: 770 SPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG----- 824 P G P G G+ GF G PG G G +GE G G G PG GL+GE G Sbjct: 1884 GPQGPPGLPGPVGPPGQ-GFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNV 1942 Query: 825 ------------------EPGDASLGF---------GMRGMPGPPGPPGPPGPPGTPVYD 857 E D S G G +G G GPPG GP G P + Sbjct: 1943 DRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFP-GE 2001 Query: 858 SNVFAESSRPGPPGLP----GNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKG 913 + + PGP G P G +GPPGP G GE G PG PG EA GE+G Sbjct: 2002 RGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERG 2061 Query: 914 DRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPR--------------GYPGIPGPKGE- 958 +RG+ G++GE+G G G G+ PGPPGPPGP+ G PG+ G KGE Sbjct: 2062 ERGEKGERGEQGRDGPPGLPGT--PGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEP 2119 Query: 959 ------------------SIRGQPGPPGPQGPPGI----GYEGRQGPPGPPGPPGPPSFP 996 RG+PGP G G PG+ G G +G PG GP GPP Sbjct: 2120 GSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPV 2179 Query: 997 GPHRQTISVPGPPGPPGPPGPPGTMGAS 1024 G H PGPPG PG GP G G S Sbjct: 2180 GGHGD----PGPPGAPGLAGPAGPQGPS 2203 Score = 479 bits (1233), Expect = e-135 Identities = 383/1082 (35%), Positives = 459/1082 (42%), Gaps = 248/1082 (22%) Query: 238 DEEGDDSDGASGDSGSGLGDARELLREETGAA--LKPRLP-------APPPVTTPPLAGG 288 D D G GDSG+ + R+ + E GA L P+ P PP P + GG Sbjct: 1849 DPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGG 1908 Query: 289 SSTEDSRSEEVE--EQTTVASLGAQTLPGS-------------------DSVSTWD---- 323 + + R E EQ G + PGS + V TWD Sbjct: 1909 TGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSG 1968 Query: 324 ----------------GSVRTPG-----GRVKEGGLKGQKGEPGVPGPPGRA----GPPG 358 G PG G E GLKG +G+PG GPPG A GPPG Sbjct: 1969 SFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPG 2028 Query: 359 ------SPCLPGPPGLPCPVSPLGPAG-PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPG 411 P PG PGLP +G AG P + G +G G GRDG PG G PG PG Sbjct: 2029 PSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPG 2088 Query: 412 -----------------EDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGP 453 E G PG G +G PG+ GD GPKGD+G PG+ G+RG PGP+G Sbjct: 2089 PPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQ 2148 Query: 454 PGPPG-PSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNS 512 G PG P R G L+GPRG PGP G G PG PG PG G Sbjct: 2149 DGNPGLPGER----------GMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAG--P 2196 Query: 513 SDVPGPAGLPGVPGREGPPG--------FPGLPGPPGPPGREGP---PGRTGQKGSLGEA 561 + GP+GL G PG GPPG GLPGPPGP G GP PG GQ G G+ Sbjct: 2197 AGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKP 2256 Query: 562 GAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGP---GLPA--------- 609 GAPG G+ G G G+ G G G PGP GP G PGP G PG GLP Sbjct: 2257 GAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPG 2316 Query: 610 -------------GFDDMEGSGGPFWSTARSA-------DGPQGPPGLPGLKGDPGV--- 646 G + G G R+ DG +G PG G KGDPGV Sbjct: 2317 GLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVP 2376 Query: 647 -----PGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKG---DPGKDGV- 697 PG PG KG++G G+PG PG+ G G GP+G G G GE+G PG++G+ Sbjct: 2377 GSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIP 2436 Query: 698 ---GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGP------------EGRPGFAG---FPG 739 G PG PG GPPG ++ + +PGP +GRPG G G Sbjct: 2437 GPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTG 2496 Query: 740 PAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDG--GALG-------------------- 777 P G +G G KG+ GS G KG+KG+ I P G GA G Sbjct: 2497 PPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDN 2556 Query: 778 --PAQKGAKGEPG---------FRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEP 826 P KG+KGEPG RG GP G+PG G G PG PG+ G+ G++GEKG+ Sbjct: 2557 GDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDV 2616 Query: 827 GDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGP------PG 880 G G RG+ G G G G G + E+ PG PGL G++G PG Sbjct: 2617 GF----MGPRGLKGERGVKGACGLDG----EKGDKGEAGPPGRPGLAGHKGEMGEPGVPG 2668 Query: 881 PKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGP 940 GA G+ G GP G FD G+ G +GD G+KGERG PG GGF G S G Sbjct: 2669 QSGAPGKEGLIGPKGDRGFD---------GQPGPKGDQGEKGERGTPGIGGFPGPS--GN 2717 Query: 941 PGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHR 1000 G GP G PG GP+G G G G +GPPG G G PG PG G Sbjct: 2718 DGSAGPPGPPGSVGPRGPE--GLQGQKGERGPPGERVVGAPGVPGAPGERGE-------- 2767 Query: 1001 QTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVR 1060 G PGP GP G G + RQ M H +G F+A Sbjct: 2768 -----QGRPGPAGPRGEKGEAALTEDDIRGFVRQEM--SQHCACQGQ--FIASGSRPLPS 2818 Query: 1061 VQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILA 1120 QL A L E + P + + + Y E+ P A PW +DD + Sbjct: 2819 YAADTAGSQLHAVPVLRVSHAEEEERVPPEDDEYSEYSEYSVEEYQDPEA-PWDSDDPCS 2877 Query: 1121 SP 1122 P Sbjct: 2878 LP 2879 Score = 373 bits (957), Expect = e-103 Identities = 246/580 (42%), Positives = 281/580 (48%), Gaps = 63/580 (10%) Query: 491 GPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPG 550 GP V GL + + P P + G++G PG GL G GPPG G PG Sbjct: 1219 GPSLDQAVSGLATALCQASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPG 1278 Query: 551 RTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAG 610 RTG G G G+ KG +G PG G G G AG PG G PG G PG PGP G Sbjct: 1279 RTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPG 1338 Query: 611 FDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGR 670 G G + + G PGLPG KGDPG G PG +G +G G G PGLPG Sbjct: 1339 ERGPRGPKGEPGAPGQVIGGE--GPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPG- 1395 Query: 671 EGIAGPQGPKGDRGSRGEKGDPGKDGV--GQPGLPGPPGPPGPVVYV------SEQDGSV 722 +G KGDRG RG G PG+ G+ G+PGLPG PG PGP V E+ S Sbjct: 1396 ---TAMKGDKGDRGERGPPG-PGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSE 1451 Query: 723 LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKG 782 PG G+PG G GP GP G +G KG+RG PGP GE GE G P G A G Sbjct: 1452 DGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGE-RGPPGPAGSRGLPG 1510 Query: 783 AKGEPGFRGPPGPYGRPGYKGEIGFPGRPG-----RPGMNGLKGEKGEPGDASL--GFGM 835 G PG +GP GP G G +GE G PGRPG P + G KGEKG+ G A G+ Sbjct: 1511 VAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGV 1570 Query: 836 RGMPGP-----PGPPGPPGPPGT-----------PVYDSNVFAESSRPGPPGLPGNQGPP 879 +G GP PG PGP G PG P DS E PG PG PG GP Sbjct: 1571 QGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPR 1630 Query: 880 GPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPG 939 G G GE G GPPG E ++G G RG G+KG++G+PG G GS PG Sbjct: 1631 GRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGS--PG 1688 Query: 940 PPGPPGPRGYPGIPGPKGESI--------------RGQPGPPGPQGPPGI-GYEGRQGPP 984 GP G RG PG PGP G + RGQ GP GP+G PG+ G G +G Sbjct: 1689 SSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIE 1748 Query: 985 GPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGAS 1024 G GPPGP PG V GP G G GPPG G S Sbjct: 1749 GFRGPPGPQGDPG-------VRGPAGEKGDRGPPGLDGRS 1781 Score = 148 bits (374), Expect = 3e-35 Identities = 103/262 (39%), Positives = 118/262 (45%), Gaps = 47/262 (17%) Query: 772 DGGALGPAQKG---AKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGD 828 DG +L A G A + F P P P Y + G+ G PG GL+G+ G PGD Sbjct: 1218 DGPSLDQAVSGLATALCQASFTTQPRPEPCPVYCPK----GQKGEPGEMGLRGQVGPPGD 1273 Query: 829 ASLGFGMRGMPGPPGPPGPPGPPG--TPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKG 886 G+PG G PGP GPPG T + RPG PG GN G PG G KG Sbjct: 1274 P-------GLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKG 1326 Query: 887 EVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGG-GFFGSSLPGPPGPPG 945 G PGP +G+ G+RG G KGE G PG G G LPG G PG Sbjct: 1327 SPGLPGP---------------RGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPG 1371 Query: 946 PRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISV 1005 P G PG GP G+ PGP GP G PG +G +G G GPPGP Sbjct: 1372 PSGPPGPRGPLGD-----PGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIA------- 1419 Query: 1006 PGPPGPPGPPGPPGTMGASSGV 1027 PG PG PG PG+ G V Sbjct: 1420 ---PGEPGLPGLPGSPGPQGPV 1438 Score = 144 bits (362), Expect = 7e-34 Identities = 134/397 (33%), Positives = 159/397 (40%), Gaps = 59/397 (14%) Query: 193 RGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDP-QVSPMHCLDEEGDDSDGASGDS 251 RG +PG + G A P +G+ L P V P +GD D G Sbjct: 2412 RGEMGQPGPS---GERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLP 2468 Query: 252 GSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQ 311 G +R E G +P P +T PP + G E E+ V S G + Sbjct: 2469 GPRGERGEPGIRGEDG---RPGQEGPRGLTGPPGSRG---------ERGEKGDVGSAGLK 2516 Query: 312 TLPGSDSVSTWDGSVRTPGGRVKEGG---LKGQKGEPGVPGPPGRAGPPGSPCLPGPPGL 368 G +V R G + E G L G KG G G PG G G P G GL Sbjct: 2517 GDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGL 2576 Query: 369 PCPVSPLGPAG-PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE--------------- 412 P LGP G P +PG PG PG+DG PG GE GD G Sbjct: 2577 PGLRGLLGPQGQPGAAGIPGD---PGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGA 2633 Query: 413 ---DGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPG-------PSF 461 DG+ GD G G PG PG G KG+ G+PGV G+ G PG +G GP G P Sbjct: 2634 CGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGP 2693 Query: 462 RHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSD----VPG 517 + D+ + G GG GP G G GPPG PG G G G+ PG Sbjct: 2694 KGDQGEKGERGTPGIGG----FPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPG 2749 Query: 518 P--AGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRT 552 G PGVPG G G G PGP GP G +G T Sbjct: 2750 ERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALT 2786 >gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] Length = 1860 Score = 490 bits (1262), Expect = e-138 Identities = 371/982 (37%), Positives = 431/982 (43%), Gaps = 226/982 (23%) Query: 228 DPQVSPMHCLDEEGDDSDGASGDSG-SGLGD-----ARELLREETGAALKPRLPAPPPVT 281 DP +SP G DGA GD G GL R+ + G A P P Sbjct: 677 DPGLSP-------GKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPE 729 Query: 282 TPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLK 339 P A G V + S G LPG + DG PG K G G+ Sbjct: 730 GSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMP 789 Query: 340 GQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP------------------- 380 G G G GPPG G PG LPGPPG+P + LG GP Sbjct: 790 GFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEP 849 Query: 381 ------ALQTVPG------------PQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQ 422 Q VPG QG PG PG G PG G+ GD G G PG GP+ Sbjct: 850 GLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPE 909 Query: 423 GFPGT---PGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDME 472 GFPG PGD GP+G KG PG G+ GP G +GP GPPG Sbjct: 910 GFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAP------------ 957 Query: 473 GSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFG-------------------VNSS 513 LE G +GFPG PG GV G PG+PGR G V Sbjct: 958 ------GLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEK 1011 Query: 514 DVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAP 573 G G PGVPG +G G PG+PG G PG GP G G +G G GA G +G +G Sbjct: 1012 GDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPD 1071 Query: 574 GPAGARGESGLAGAPGPAGPPGPPGP---------------PGPPGPGLPAGFDDMEGSG 618 GPAG +G GL G PGP G PG PG PG PGP P G + G Sbjct: 1072 GPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEP 1131 Query: 619 GPFWSTARSADGPQGPPGL------PGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREG 672 GP + GP GPPG PG G+PG+PG G KG++G G PG GL G+ G Sbjct: 1132 GP-----QGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRG 1186 Query: 673 ---IAGPQGPKGDRGSRGEKGDPGKDGV----GQPGLPGPPGPPGPVVYVSEQDGSVLSV 725 + G GP G G +G++GDPG DG GQ GL G GPPGP V V Sbjct: 1187 EPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPP--------GVTGV 1238 Query: 726 PGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDG--GALGPA---- 779 GPEG+ G G G G KG G +G+ G G G+ G PG+ P G G+LGP Sbjct: 1239 RGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTP-GPKGSRGSLGPTGAPG 1297 Query: 780 QKGAKGEPGFRG------------PPGPYGRPGYKGEIGF----PGRPGRPGMNGLKGEK 823 + GA+GEPG G PPGP G G +GE G PG PG G G +G++ Sbjct: 1298 RMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDR 1357 Query: 824 GEPGDASLGF-----GMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR--------PGPP 870 GEPGD G+RG PG G PG PGP G P + AE + PG Sbjct: 1358 GEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRR 1417 Query: 871 GLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKG---ERGEP 927 G+ G QG PGP+G G G G G +A +GE+GD GD G G +RG P Sbjct: 1418 GVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNP 1477 Query: 928 GGGGFFG----------SSLPGPPGPPGPRGYPG---IPGPKGE-SIRGQPGPPG----- 968 G G G S LPG GPPG RG G +PG +GE +GQPG G Sbjct: 1478 GVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFP 1537 Query: 969 -------PQGPPG-IGYEGRQGPPGPPGPPG------------PPSFPGPH-----RQTI 1003 P+GPPG IG++G QGP GPPG G P PGP R Sbjct: 1538 GMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDW 1597 Query: 1004 SVPGPPGPPGP---PGPPGTMG 1022 + GP GPPGP PGPPG G Sbjct: 1598 GLQGPRGPPGPRGRPGPPGPPG 1619 Score = 489 bits (1258), Expect = e-138 Identities = 346/882 (39%), Positives = 394/882 (44%), Gaps = 144/882 (16%) Query: 258 ARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSD 317 AR++ + PR P P TTP L + S S + T + L GS Sbjct: 563 ARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSP----RPTSSGYSIFHLAGST 618 Query: 318 SVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGP 377 G P G + GL G G PG+PG PG GP G P G PGLP P G Sbjct: 619 PFPLLMG----PPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQ 674 Query: 378 AG-PALQT------------VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGP--- 421 G P L +PG G PGPPGR G G G G PGE G+PG G Sbjct: 675 KGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGA 734 Query: 422 ------QGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS 474 QG PG GD GPKG +G G+ G G PG G G PG + K M Sbjct: 735 KGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGK-----MGMP 789 Query: 475 GFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFG----VNSSDVPGPAGLPGVPGREGP 530 GF G + RGP G G PG G+PG PG PG G + PGP G+ G+ G G Sbjct: 790 GFPG-VFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGE 848 Query: 531 PGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGP 590 PG G G G PG G PG G KGS G PG G++G PGP G G+ G G PGP Sbjct: 849 PGLKGDKGEQGVPGVSGDPGFQGDKGS---QGLPGFPGARGKPGPLGKVGDKGSIGFPGP 905 Query: 591 AGPPGPPGPPGPPGPGLPAGFDDMEGS---GGPFWSTARSAD-GPQGPPGLPGLKGDPGV 646 GP G PG GPPG P G G+ GP D GP GPPG PGL+G PG Sbjct: 906 PGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGR 965 Query: 647 PGLPGAKGEVGADGVPGFPGLPGREGIAGPQ---------------GPKGDRGSRGEKGD 691 G P G G DGV G PG PGR G G Q G KGDRG G G Sbjct: 966 KGFP---GRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGV 1022 Query: 692 PG-KDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFP------------ 738 PG K +G PG+PG G PG PGP+G PG G P Sbjct: 1023 PGPKGSMGHPGMPGGMGTPGE--------------PGPQGPPGSRGPPGMRGAKGRRGPR 1068 Query: 739 GPAGPKGNLGSKGERGSPGPKGEKGEPGSI-FSPDGGALG-------------PAQKGAK 784 GP GP G GS+G +G PGP+G G PG + + G LG P KG Sbjct: 1069 GPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLP 1128 Query: 785 GEPGFRGPPGPYGRPGY------KGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGM 838 GEPG +GP GP G PG G +G PG PG GM G G G PG+ L G RG Sbjct: 1129 GEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGL-IGQRGE 1187 Query: 839 PGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFP 898 PG G GP GP G G PG G G G +G GE GPPGPPG Sbjct: 1188 PGLEGDSGPMGPDGL----------KGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTG 1237 Query: 899 FDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE 958 + ++ +GEKG G G KG +G+ G G G PGPPG PGP+G G GP Sbjct: 1238 VRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGD--PGPPGTPGPKGSRGSLGP--- 1292 Query: 959 SIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGP 1017 G PG G QG PG+ GY+G +G GP GPPGP G + GPPGPPG GP Sbjct: 1293 --TGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGP 1350 Query: 1018 PGTMG-----------ASSGVRLWATRQAMLGQV-HEVPEGW 1047 G G GV+ + GQ H P GW Sbjct: 1351 VGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGW 1392 Score = 449 bits (1154), Expect = e-125 Identities = 315/778 (40%), Positives = 357/778 (45%), Gaps = 149/778 (19%) Query: 309 GAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSPCLPGPP 366 G+Q LPG G + G + G G G +G PG GPPG GP G PG Sbjct: 874 GSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGAR 933 Query: 367 GLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPG---------DPGEDGKPG 417 GLP P LGP G GP GPPG PG +G PGR G PG +PG+ G+PG Sbjct: 934 GLPGPRGQLGPEGDE-----GPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPG 988 Query: 418 DTGPQGFPG---------------------TPGDVGPKGDKGDPGV----GERGPPGPQG 452 G QGF G PG GPKG G PG+ G G PGPQG Sbjct: 989 PVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQG 1048 Query: 453 PPGPPGP-SFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVN 511 PPG GP R K G G+ +G RG GPPGP G PG PG+ G G Sbjct: 1049 PPGSRGPPGMRGAKGRRGPRGPDGPAGE----QGSRGLKGPPGPQGRPGRPGQQGVAGER 1104 Query: 512 SSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGP---PGRTGQKG---SLGEAGAPG 565 G G PG+PG GPPG GLPG PGP G +GP PG G KG ++GE G PG Sbjct: 1105 GH--LGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPG 1162 Query: 566 HKGSKGAPGPAGA---------RGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEG 616 G KG GP G RGE GL G GP GP G G G PGP G EG Sbjct: 1163 EAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEG 1222 Query: 617 SGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPG------LPGR 670 G DGP GPPG+ G++G G G G KG GA G G+ G +PG Sbjct: 1223 LMGE--------DGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGD 1274 Query: 671 EGIAGPQGPKGDRGSRGEKGDPGKDGV-GQPGLPG---------PPGPPGPVVYVSEQ-- 718 G G GPKG RGS G G PG+ G G+PGL G P GPPGP EQ Sbjct: 1275 PGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGE 1334 Query: 719 DGSVLSVPGP------------EGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPG 766 DG PGP G PG G+PG G +G G G++G PG G +G PG Sbjct: 1335 DGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPG 1394 Query: 767 SIFSP--------DGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNG 818 S G A P ++G +G G GP G GR G +G G G PGR G G Sbjct: 1395 PKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAG 1454 Query: 819 LKGEKGEPGDAS-LG-FGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPG---PPG-- 871 +GE+G+ GD +G G RG PG G PG GPPG ES PG PPG Sbjct: 1455 QQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFK-------GESGLPGQLGPPGKR 1507 Query: 872 -------LPGNQGPPGPKGAKGE------------VGPPGPPGQFPFDFLQLEAE---MK 909 LPGNQG PG KG G+ GP GPPG F +Q + Sbjct: 1508 GTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLM 1567 Query: 910 GEKGDRGDAGQKGERGEPGGGGFFGS----SLPGPPGPPGPRGYPGIPGPKGESIRGQ 963 G++G G G G G PG G GS L GP GPPGPRG PG PGP G I+ Q Sbjct: 1568 GKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGPIQLQ 1625 Score = 396 bits (1018), Expect = e-110 Identities = 309/864 (35%), Positives = 361/864 (41%), Gaps = 163/864 (18%) Query: 277 PPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG 336 P + T P A +S +S ++T +S LP V V R E Sbjct: 365 PKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPAEK 424 Query: 337 GLKGQKGEPGVPGPPGRAGPPGSPCLPGP-PGLPCPVSPLG-----PAGPALQTVPGPQG 390 ++ G P P P R PP + P P L + + PA T P Sbjct: 425 PIQRNPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPF 484 Query: 391 PPGPPGRDGTPGRDGEPGDPGEDGKP--GDTGPQGFPG--TPGDVGPKGDK---GDPGVG 443 TPG P P G + P+ P TPG P G K G Sbjct: 485 TALSSSPAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSA-PTGSKKPIGSEASK 543 Query: 444 ERGPPGPQGPPGP--PGPSFRHDKLTFIDMEGS--------------------------- 474 + GP P P PG + R L+ + S Sbjct: 544 KAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPR 603 Query: 475 --GFGGDLEALRGPRGFP---GPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVP---- 525 G + L G FP GPPGP G GLPG PG LPG+P Sbjct: 604 PTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPG--------------LPGLPGIPG 649 Query: 526 -----GREGPPGFPGLPGPPGPPGREGPPG------RTGQKGSL------GEAGAPGHKG 568 G GP G PGLPGPPG G++G PG G KG + G G PG KG Sbjct: 650 ARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKG 709 Query: 569 SKGAPGPAGARGES---------GLAGAPGPAGPPGPPGPPGPPGP----GLPAGFDDME 615 KG PGPAG GE G G PG G PGP G PGP G GLP F Sbjct: 710 HKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPG 769 Query: 616 GSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAG 675 G G G PG PG+ G+ G PGL G GE+G G PG PGL G G+ G Sbjct: 770 SDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLG 829 Query: 676 P---QGPKGDRGSRGEKGDPG-KDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGR 731 P GPKG +G G G+PG K G+ G+PG G PG G +G Sbjct: 830 PIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPG-----------FQGDKGSQGL 878 Query: 732 PGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSP-DGGALG----------PAQ 780 PGF G G GP G +G KG G PGP G +G PG I P D G G P Sbjct: 879 PGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGP 938 Query: 781 KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPG-------DASLGF 833 +G G G GP GP G PG +G+ G G PGRPG++G+KGE G+PG +GF Sbjct: 939 RGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGF 998 Query: 834 -------------GMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPG 880 G RGM GPPG PGP G G P + PGP G PG++GPPG Sbjct: 999 IGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGM-GTPGEPGPQGPPGSRGPPG 1057 Query: 881 PKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGP 940 +GAKG GP GP G GE+G RG G G +G PG G G + G Sbjct: 1058 MRGAKGRRGPRGPDGP------------AGEQGSRGLKGPPGPQGRPGRPGQQG--VAGE 1103 Query: 941 PGPPGPRGYPGIPGPKG-ESIRGQPGPPGPQGPPG-IGYEGRQGPPGPPGPPGPPSFPGP 998 G G RG+PGIPGP G +G PG PGPQGP G IG G GP GPPG G P PG Sbjct: 1104 RGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPG- 1162 Query: 999 HRQTISVPGPPGPPGPPGPPGTMG 1022 + G GP G PG G +G Sbjct: 1163 ---EAGMKGDLGPLGTPGEQGLIG 1183 Score = 390 bits (1001), Expect = e-108 Identities = 362/1054 (34%), Positives = 426/1054 (40%), Gaps = 231/1054 (21%) Query: 150 AASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPGAGLFVAQAG 209 + +F L G+W HLAL + G V L C + + L R L+PG G F+ Sbjct: 144 SVAFDLDMHDGRWHHLALELRGRTVTLVTACGQRRVPVLLPFHRDPALDPG-GSFLFGKM 202 Query: 210 GADPDKFQGVIAELKVRRDPQVSPMHC--LDEEGDDSDG--------ASGDSGSGLGDAR 259 +F+G + + + QV+ +C L ++ +D S DSG Sbjct: 203 NPHAVQFEGALCQFSIYPVTQVAHNYCTHLRKQCGQADTYQSPLGPLFSQDSGRPFTFQS 262 Query: 260 E--LLREETGAALKPRLPAPPPVTTP--PLAGGSSTEDSRSEEVEEQTTVASLG-AQT-- 312 + LL E P L + P P +A + T+ R+ +A G AQT Sbjct: 263 DLALLGLENLTTATPALGSLPAGRGPRGTVAPATPTKPQRTSPTNPHQHMAVGGPAQTPL 322 Query: 313 LPGSDSVS---------TWDGSVRTPGGRV-----KEGGLKGQKGEPGVPGPPGRA-GPP 357 LP S S + GS RTP K K K P P P + P Sbjct: 323 LPAKLSASNALDPMLPASVGGSTRTPRPAAAQPSQKITATKIPKSLPTKPSAPSTSIVPI 382 Query: 358 GSP--------------CLP-----GPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRD 398 SP LP P P P PA +Q PG PP P R Sbjct: 383 KSPHPTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPAEKPIQRNPGMPRPPPPSTRP 442 Query: 399 --------------------------------------------------GTPGRDGEPG 408 TPG Sbjct: 443 LPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSPAPTPGSTRSTR 502 Query: 409 DPGEDGKP--GDTGPQGFPG--TPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHD 464 P P G + P+ P TPG P G K G GP+ P P P Sbjct: 503 PPATMVPPTSGTSTPRTAPAVPTPGS-APTGSKKPIGSEASKKAGPKSSPRKPVPLRPGK 561 Query: 465 KLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP-------- 516 + + DL PR P P L P +F ++SS P Sbjct: 562 AARDVPL------SDLTTRPSPR--QPQPSQQTTPALVLAPAQF-LSSSPRPTSSGYSIF 612 Query: 517 ------------GPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAP 564 GP G G G GPPG PGLPG PG G GPPG G G G GA Sbjct: 613 HLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAK 672 Query: 565 GHKGSKG-APGPA--GARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPF 621 G KG G +PG A GA+G+ GL G G GPPG G G PG PAG +G GP Sbjct: 673 GQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPG---PAGHPGEQGQPGPE 729 Query: 622 WSTARSA----DGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQ 677 S G GP G PG KG G GLPG G G+DG G PG+PG+ G Sbjct: 730 GSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKR---GKM 786 Query: 678 GPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAG 736 G G G GE+G PG DG G+ GLPGPPG PG + G G G G Sbjct: 787 GMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLI--------------GDLGVLGPIG 832 Query: 737 FPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGF---RGPP 793 +PGP G KG +GS GE G G KGE+G PG S D G G KG++G PGF RG P Sbjct: 833 YPGPKGMKGLMGSVGEPGLKGDKGEQGVPG--VSGDPGFQG--DKGSQGLPGFPGARGKP 888 Query: 794 GPYGRPGYKGEIGFPGRP---------GRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGP 844 GP G+ G KG IGFPG P G PG NG +G KG+PG L G RG GP G Sbjct: 889 GPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLP-GPRGQLGPEGD 947 Query: 845 PGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPF-DFLQ 903 GP GPPG P + +PG G PG G G KG G+ G PGP G+ F F+ Sbjct: 948 EGPMGPPGAPGLE-------GQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIG 1000 Query: 904 LEAE--MKGEKGDR------GDAGQKGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIPG 954 L E + GEKGDR G G KG G PG G G+ PGP GPPG RG PG+ G Sbjct: 1001 LVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRG 1060 Query: 955 PKG-------------ESIRGQPGPPGPQGPPG-------------IGYEGRQGPPGPPG 988 KG + RG GPPGPQG PG +G G G PGP G Sbjct: 1061 AKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSG 1120 Query: 989 PPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1022 PPG PG PGP GP GP GPPG MG Sbjct: 1121 PPGTKGLPGE-------PGPQGPQGPIGPPGEMG 1147 Score = 205 bits (522), Expect = 2e-52 Identities = 165/471 (35%), Positives = 194/471 (41%), Gaps = 93/471 (19%) Query: 240 EGDDS----DGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTT---PPLAGGSSTE 292 EGD DG GD G D + + G + P PP VT P G E Sbjct: 1191 EGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGE 1250 Query: 293 DSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPG 352 R+ + LG +PG G TPG KG +G G G PG Sbjct: 1251 KGRTGAKGAKGYQGQLGEMGVPGDP------GPPGTPGP-------KGSRGSLGPTGAPG 1297 Query: 353 RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQT--------VPGPQGPPGPPGRDGTPGRD 404 R G G P L G G V PLGP GP + GP GPPG G G G Sbjct: 1298 RMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDR 1357 Query: 405 GEPGDPG---------------EDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV----GER 445 GEPGDPG + G+PG GP+G+PG G G +G KG G G R Sbjct: 1358 GEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRR 1417 Query: 446 GPPGPQGPPGPPGPSFRHDKLTFIDMEG----SGFGGDLEALRGPRGFPGPPGP------ 495 G G QG PGP G R +G G G + +G G PGP GP Sbjct: 1418 GVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQ-QGEQGDDGDPGPMGPAGKRGN 1476 Query: 496 PGVPGLPGEPGRFGVNS-SDVPGPAGLPG---------VPGREGPPG------------F 533 PGV GLPG G G S +PG G PG +PG +G PG F Sbjct: 1477 PGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGF 1536 Query: 534 PGLPG---PPGPPGR---------EGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGE 581 PG+ G P GPPG GPPG G++G +G G G G G G G+RG+ Sbjct: 1537 PGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGD 1596 Query: 582 SGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQ 632 GL G GP GP G PGPPGPPG + DD+ G+ W A P+ Sbjct: 1597 WGLQGPRGPPGPRGRPGPPGPPGGPIQLQQDDL-GAAFQTWMDTSGALRPE 1646 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.142 0.459 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 98,932,408 Number of Sequences: 37866 Number of extensions: 9245670 Number of successful extensions: 389828 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 869 Number of HSP's successfully gapped in prelim test: 2032 Number of HSP's that attempted gapping in prelim test: 34754 Number of HSP's gapped (non-prelim): 48004 length of query: 1336 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1222 effective length of database: 13,930,794 effective search space: 17023430268 effective search space used: 17023430268 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.