Guide to the Human Genome
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Search of human proteins with 14916433

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14916433 naked cuticle homolog 1 [Homo sapiens]
         (470 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14916433 naked cuticle homolog 1 [Homo sapiens]                    967   0.0  
gi|14916427 naked cuticle homolog 2 [Homo sapiens]                    311   8e-85
gi|239757043 PREDICTED: functional smad suppressing element 18 [...    52   2e-06
gi|239751555 PREDICTED: functional smad suppressing element 18 [...    52   2e-06
gi|239746067 PREDICTED: functional smad suppressing element 18 [...    52   2e-06
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    44   2e-04
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    44   2e-04
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    44   2e-04
gi|124107614 PR domain containing 13 [Homo sapiens]                    44   4e-04
gi|32698730 nuclear fragile X mental retardation protein interac...    43   7e-04
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        42   0.001
gi|197304786 IQ motif and Sec7 domain 1 isoform a [Homo sapiens]       42   0.001
gi|148762982 hypothetical protein LOC387640 [Homo sapiens]             42   0.001
gi|61966923 forkhead box B2 [Homo sapiens]                             42   0.001
gi|84105335 mesenchyme homeobox 2 [Homo sapiens]                       42   0.001
gi|192447423 frequenin homolog isoform 2 [Homo sapiens]                42   0.002
gi|17738308 frequenin homolog isoform 1 [Homo sapiens]                 42   0.002
gi|27894361 nuclear receptor subfamily 4, group A, member 3 isof...    41   0.002
gi|27894359 nuclear receptor subfamily 4, group A, member 3 isof...    41   0.002
gi|27894357 nuclear receptor subfamily 4, group A, member 3 isof...    41   0.002
gi|27894355 nuclear receptor subfamily 4, group A, member 3 isof...    41   0.002
gi|21361559 visinin-like 1 [Homo sapiens]                              40   0.003
gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo s...    40   0.006
gi|187828880 calcium channel, alpha 1A subunit isoform 3 [Homo s...    40   0.006
gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regula...    40   0.006
gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regula...    40   0.006
gi|19913446 hippocalcin [Homo sapiens]                                 40   0.006
gi|40288197 GATA binding protein 6 [Homo sapiens]                      39   0.008
gi|55770830 chromobox homolog 4 [Homo sapiens]                         39   0.010
gi|122937233 discs, large (Drosophila) homolog-associated protei...    39   0.013

>gi|14916433 naked cuticle homolog 1 [Homo sapiens]
          Length = 470

 Score =  967 bits (2499), Expect = 0.0
 Identities = 470/470 (100%), Positives = 470/470 (100%)

Query: 1   MGKLHSKPAAVCKRRESPEGDSFAVSAAWARKGIEEWIGRQRCPGGVSGPRQLRLAGTIG 60
           MGKLHSKPAAVCKRRESPEGDSFAVSAAWARKGIEEWIGRQRCPGGVSGPRQLRLAGTIG
Sbjct: 1   MGKLHSKPAAVCKRRESPEGDSFAVSAAWARKGIEEWIGRQRCPGGVSGPRQLRLAGTIG 60

Query: 61  RSTRELVGDVLRDTLSEEEEDDFRLEVALPPEKTDGLGSGDEKKMERVSEPCPGSKKQLK 120
           RSTRELVGDVLRDTLSEEEEDDFRLEVALPPEKTDGLGSGDEKKMERVSEPCPGSKKQLK
Sbjct: 61  RSTRELVGDVLRDTLSEEEEDDFRLEVALPPEKTDGLGSGDEKKMERVSEPCPGSKKQLK 120

Query: 121 FEELQCDVSMEEDSRQEWTFTLYDFDNNGKVTREDITSLLHTIYEVVDSSVNHSPTSSKM 180
           FEELQCDVSMEEDSRQEWTFTLYDFDNNGKVTREDITSLLHTIYEVVDSSVNHSPTSSKM
Sbjct: 121 FEELQCDVSMEEDSRQEWTFTLYDFDNNGKVTREDITSLLHTIYEVVDSSVNHSPTSSKM 180

Query: 181 LRVKLTVAPDGSQSKRSVLVNQADLQSARPRAETKPTEDLRSWEKKQRAPLRFQGDSRLE 240
           LRVKLTVAPDGSQSKRSVLVNQADLQSARPRAETKPTEDLRSWEKKQRAPLRFQGDSRLE
Sbjct: 181 LRVKLTVAPDGSQSKRSVLVNQADLQSARPRAETKPTEDLRSWEKKQRAPLRFQGDSRLE 240

Query: 241 QSGCYHHCVDENIERRNHYLDLAGIENYTSQFGPGSPSVAQKSELPPRTSNPTRSRSHEP 300
           QSGCYHHCVDENIERRNHYLDLAGIENYTSQFGPGSPSVAQKSELPPRTSNPTRSRSHEP
Sbjct: 241 QSGCYHHCVDENIERRNHYLDLAGIENYTSQFGPGSPSVAQKSELPPRTSNPTRSRSHEP 300

Query: 301 EAIHIPHRKPQGVDPASFHFLDTPIAKVSELQQRLRGTQDGSKHFVRSPKAQGKSVGVGH 360
           EAIHIPHRKPQGVDPASFHFLDTPIAKVSELQQRLRGTQDGSKHFVRSPKAQGKSVGVGH
Sbjct: 301 EAIHIPHRKPQGVDPASFHFLDTPIAKVSELQQRLRGTQDGSKHFVRSPKAQGKSVGVGH 360

Query: 361 VARGARNKPPLGPAIPAVSPSAHLAASPALLPSLAPLGHKKHKHRAKESQQGCRGLQAPL 420
           VARGARNKPPLGPAIPAVSPSAHLAASPALLPSLAPLGHKKHKHRAKESQQGCRGLQAPL
Sbjct: 361 VARGARNKPPLGPAIPAVSPSAHLAASPALLPSLAPLGHKKHKHRAKESQQGCRGLQAPL 420

Query: 421 ASGGPVLGREHLRELPALVVYESQAGQPVQRHEHHHHHEHHHHYHHFYQT 470
           ASGGPVLGREHLRELPALVVYESQAGQPVQRHEHHHHHEHHHHYHHFYQT
Sbjct: 421 ASGGPVLGREHLRELPALVVYESQAGQPVQRHEHHHHHEHHHHYHHFYQT 470


>gi|14916427 naked cuticle homolog 2 [Homo sapiens]
          Length = 451

 Score =  311 bits (797), Expect = 8e-85
 Identities = 208/482 (43%), Positives = 263/482 (54%), Gaps = 49/482 (10%)

Query: 1   MGKLHSKPAAVC-KRRESPEGDSFAVSA-AWARKGIEEWIGRQRCPGGVSGPRQLRLAGT 58
           MGKL SK AA   KRRESPEGDSF  SA A  RKG EE                   A  
Sbjct: 1   MGKLQSKHAAAARKRRESPEGDSFVASAYASGRKGAEE-------------------AER 41

Query: 59  IGRSTRELVGDVLRDTLSEEEEDDFRLEVALPPEKTDG-------LGSGDEKKMERVSEP 111
             R  +EL     ++      ED   L+VALP EK +G       L + D ++      P
Sbjct: 42  RARDKQELPNGDPKE--GPFREDQCPLQVALPAEKAEGREHPGQLLSADDGERAANREGP 99

Query: 112 CPGSKKQLKFEELQCDVSMEEDSRQEWTFTLYDFDNNGKVTREDITSLLHTIYEVVDSSV 171
                ++L  + LQCDVS+EED RQEWTFTLYDFDN GKVTRED++SL+HTIYEVVD+SV
Sbjct: 100 RGPGGQRLNIDALQCDVSVEEDDRQEWTFTLYDFDNCGKVTREDMSSLMHTIYEVVDASV 159

Query: 172 NHSPTSSKMLRVKLTVAPDGSQSKRSVLVNQADLQSARPRAETKPTEDLRSWEKKQRAPL 231
           NHS  SSK LRVKLTV+P+ S  ++       D +  R R E +  E+ R  +++  A +
Sbjct: 160 NHSSGSSKTLRVKLTVSPEPSSKRKEGPPAGQDREPTRCRMEGELAEEPRVADRRLSAHV 219

Query: 232 RFQGDSRLEQSGCYHHCVDENIERRNHYLDLAGIENYTSQFGPGSPSVAQKSELPPRTSN 291
           R         S    +CVDEN ERRNHYLDLAGIENYTS+FGPGSP V  K E   R S+
Sbjct: 220 RRPSTDPQPCSERGPYCVDENTERRNHYLDLAGIENYTSRFGPGSPPVQAKQEPQGRASH 279

Query: 292 -PTRSRSHEPEAIHIPHRKPQ----GVDPASFHFLDTPIAKVSELQQRLRGTQDGSKHFV 346
              RSRS EP+   + HR+ Q     V PAS      P A+  + Q R +G +   K F+
Sbjct: 280 LQARSRSQEPDTHAVHHRRSQVLVEHVVPAS-----EPAARALDTQPRPKGPE---KQFL 331

Query: 347 RSPKAQGKSVGVGHVARGARNKPPLGPAIPAVSPSAHLAASPALLPSLAPLGHKKHKHRA 406
           +SPK  GK  GV   ++  +      PA+  + P A         P   P GHK+++ + 
Sbjct: 332 KSPKGSGKPPGVPASSKSGKAFSYYLPAV--LPPQAPQDGHHLPQPPPPPYGHKRYRQKG 389

Query: 407 KESQQGCRGLQAPLASGGPVLGREHLRELPALVVYESQAGQPVQRHEHHHHHEHHHHYHH 466
           +E   G   L+AP A    V   E +R+LP     E  A   +QRHEHHHHHEHHHH+HH
Sbjct: 390 RE---GHSPLKAPHAQPATV-EHEVVRDLPPTPAGEGYAVPVIQRHEHHHHHEHHHHHHH 445

Query: 467 FY 468
            +
Sbjct: 446 HH 447


>gi|239757043 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 996

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 32/102 (31%), Positives = 44/102 (43%), Gaps = 5/102 (4%)

Query: 365 ARNKPPLGPAIPAVSPSAHLAASPALLPSLAPLGHKKHKHRAKESQQGCRGLQAPLASGG 424
           A + PP      A + +A   + PA   S  P  H  H     E ++   G     ++  
Sbjct: 571 AGSTPPADSVAAAGAGAAAAGSGPA--GSRVPAPHHPH---LLEGRKAGGGSYHHSSAFR 625

Query: 425 PVLGREHLRELPALVVYESQAGQPVQRHEHHHHHEHHHHYHH 466
           PV G++    L  L    + A    Q H HHHHH HHHH+HH
Sbjct: 626 PVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHH 667


>gi|239751555 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 32/102 (31%), Positives = 44/102 (43%), Gaps = 5/102 (4%)

Query: 365 ARNKPPLGPAIPAVSPSAHLAASPALLPSLAPLGHKKHKHRAKESQQGCRGLQAPLASGG 424
           A + PP      A + +A   + PA   S  P  H  H     E ++   G     ++  
Sbjct: 571 AGSTPPADSVAAAGAGAAAAGSGPA--GSRVPAPHHPH---LLEGRKAGGGSYHHSSAFR 625

Query: 425 PVLGREHLRELPALVVYESQAGQPVQRHEHHHHHEHHHHYHH 466
           PV G++    L  L    + A    Q H HHHHH HHHH+HH
Sbjct: 626 PVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHH 667


>gi|239746067 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 32/102 (31%), Positives = 44/102 (43%), Gaps = 5/102 (4%)

Query: 365 ARNKPPLGPAIPAVSPSAHLAASPALLPSLAPLGHKKHKHRAKESQQGCRGLQAPLASGG 424
           A + PP      A + +A   + PA   S  P  H  H     E ++   G     ++  
Sbjct: 571 AGSTPPADSVAAAGAGAAAAGSGPA--GSRVPAPHHPH---LLEGRKAGGGSYHHSSAFR 625

Query: 425 PVLGREHLRELPALVVYESQAGQPVQRHEHHHHHEHHHHYHH 466
           PV G++    L  L    + A    Q H HHHHH HHHH+HH
Sbjct: 626 PVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHH 667


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
           [Homo sapiens]
          Length = 2191

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 17/30 (56%), Positives = 20/30 (66%), Gaps = 1/30 (3%)

Query: 440 VYESQAGQPVQRHEHHHH-HEHHHHYHHFY 468
           V E+ A  P Q+H HHHH H HHHH HH +
Sbjct: 14  VGEAPAAPPHQQHHHHHHAHHHHHHAHHLH 43


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
           [Homo sapiens]
          Length = 2231

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 17/30 (56%), Positives = 20/30 (66%), Gaps = 1/30 (3%)

Query: 440 VYESQAGQPVQRHEHHHH-HEHHHHYHHFY 468
           V E+ A  P Q+H HHHH H HHHH HH +
Sbjct: 14  VGEAPAAPPHQQHHHHHHAHHHHHHAHHLH 43


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
           [Homo sapiens]
          Length = 2178

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 17/30 (56%), Positives = 20/30 (66%), Gaps = 1/30 (3%)

Query: 440 VYESQAGQPVQRHEHHHH-HEHHHHYHHFY 468
           V E+ A  P Q+H HHHH H HHHH HH +
Sbjct: 14  VGEAPAAPPHQQHHHHHHAHHHHHHAHHLH 43


>gi|124107614 PR domain containing 13 [Homo sapiens]
          Length = 707

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 37/124 (29%), Positives = 42/124 (33%), Gaps = 11/124 (8%)

Query: 341 GSKHFVRSPKAQGKSVGVGHVARGARNKPPLGPAIPAVSPSAHLAASPALLPSLAPLGHK 400
           G +   R+    G + G GH   G       G    A  P    A  PA L   A   H 
Sbjct: 251 GKEQLDRALDMSGAARGQGHFL-GIVGGSSAGVGSLAFYPGVRSAFKPAGLARAAAAAHG 309

Query: 401 KHKHRAKESQQGCRGLQAPLASGGPVLGREHLRELPALVVYESQAGQPVQRHEHHHHHEH 460
                   S+QG       L  GG   GR    E        S AG       HHHHH H
Sbjct: 310 DPYREESSSKQGAGLALGRLLGGGRACGRPGSGE-------NSAAGGA---GHHHHHHAH 359

Query: 461 HHHY 464
           HHH+
Sbjct: 360 HHHH 363


>gi|32698730 nuclear fragile X mental retardation protein
           interacting protein 2 [Homo sapiens]
          Length = 695

 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 16/36 (44%), Positives = 20/36 (55%), Gaps = 9/36 (25%)

Query: 442 ESQAGQPVQRHEHHHHHEHH---------HHYHHFY 468
           E + GQP  +H H HHH HH         HH+HH+Y
Sbjct: 2   EEKPGQPQPQHHHSHHHPHHHPQQQQQQPHHHHHYY 37



 Score = 35.8 bits (81), Expect = 0.086
 Identities = 13/27 (48%), Positives = 17/27 (62%), Gaps = 4/27 (14%)

Query: 447 QPVQRHEHHHH----HEHHHHYHHFYQ 469
           Q  Q H HHH+    H H+HH+HH +Q
Sbjct: 26  QQQQPHHHHHYYFYNHSHNHHHHHHHQ 52



 Score = 33.1 bits (74), Expect = 0.56
 Identities = 10/17 (58%), Positives = 11/17 (64%)

Query: 452 HEHHHHHEHHHHYHHFY 468
           H H+HHH HHH   H Y
Sbjct: 41  HSHNHHHHHHHQQPHQY 57



 Score = 30.0 bits (66), Expect = 4.7
 Identities = 12/33 (36%), Positives = 16/33 (48%), Gaps = 5/33 (15%)

Query: 442 ESQAGQPVQRHE-----HHHHHEHHHHYHHFYQ 469
           + Q  QP   H      H H+H HHHH+   +Q
Sbjct: 24  QQQQQQPHHHHHYYFYNHSHNHHHHHHHQQPHQ 56



 Score = 29.3 bits (64), Expect = 8.1
 Identities = 10/18 (55%), Positives = 11/18 (61%), Gaps = 1/18 (5%)

Query: 452 HEHHHHHEHHHHYHHFYQ 469
           H HHHHH HH   H + Q
Sbjct: 43  HNHHHHH-HHQQPHQYLQ 59


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 61/251 (24%), Positives = 95/251 (37%), Gaps = 31/251 (12%)

Query: 175  PTSSKMLRVKLTVAPDGSQSKRSVLVNQADLQSARPRAETKPTEDLRSWEKKQRAPLRFQ 234
            P S    R+ + ++ + + S+ S  ++  +  S R R    P +DL     ++R     Q
Sbjct: 1048 PGSRPRSRIPVLLSEEDTGSEPSGSLSAKERWSKRAR----PQQDLARLVMEKR-----Q 1098

Query: 235  GDSRLEQSGCYHHCVDENIERRNHYLDLAGIENYTSQFGPGSP-------SVAQKSELPP 287
            G   L  +        E   R +  L   G E  T    P +        + A +S +P 
Sbjct: 1099 GRLLLRLASGASSSSSEEQRRASETLSGTGSEEDTPASEPAAALPRKSGRAAATRSRIP- 1157

Query: 288  RTSNPTRSRSHEPEAIHIPHRKPQGVDPASFHFLDTPIAKVSELQQRLRGTQDGSKHF-- 345
                P   R   P A   P  +  G  PA    LDT I    +LQ     T  GS     
Sbjct: 1158 ---RPIGLRMPMPVAAQQPASRSHGAAPA----LDTAITSRLQLQ-----TPPGSATAAD 1205

Query: 346  VRSPKAQGKSVGVGHVARGARNKPPLGPAIPAVSPSAHLAASPALLPSLAPLGHKKHKHR 405
            +R  +  G+ +G G    GAR   P  P +PA + +A  A++     SL+        H+
Sbjct: 1206 LRPKQPPGRGLGPGRAQAGARPPAPRSPRLPASTSAARNASASPRSQSLSRRESPSPSHQ 1265

Query: 406  AKESQQGCRGL 416
            A+      RG+
Sbjct: 1266 ARPGVPPPRGV 1276


>gi|197304786 IQ motif and Sec7 domain 1 isoform a [Homo sapiens]
          Length = 1114

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 69/311 (22%), Positives = 110/311 (35%), Gaps = 88/311 (28%)

Query: 183  VKLTVAPDGSQSKRSVLVNQADLQSARPRAETKPTEDLRSWEKKQRAPLRFQGDSRLEQS 242
            ++LT +  G+  K  VL+N     +  P+   K T+DLR              +S  E  
Sbjct: 811  IRLTSSVPGADIK--VLIN---FNAPNPQDRKKFTDDLR--------------ESIAEVQ 851

Query: 243  GCYHHCVDENIERRNHYLDLAGIENYTSQFGPGSPSVAQKSELPPRTSNPTRSRSHEPEA 302
                H ++  +E+               Q G   PS++Q S L   + N T SR+     
Sbjct: 852  EMEKHRIESELEK---------------QKGVVRPSMSQCSSLKKESGNGTLSRA----C 892

Query: 303  IHIPHRKPQGVDPASFHFLDTPIAKVSELQQRLRGTQDGSKH------FVRSPKAQGKSV 356
            +   +   +G+  ++   L + +  +SE  +R R +  GS         + SP  + ++ 
Sbjct: 893  LDDSYASGEGLKRSA---LSSSLRDLSEAGKRGRRSSAGSLESNVEGSIISSPHMRRRAT 949

Query: 357  G------------------VGHVARGARNKPPLGPAIPAVSPSAHLAASPALLPSLAPLG 398
                               +G +    R KPP         P AHL ++PAL P   P+ 
Sbjct: 950  STRECPSRPHQTMPNSSSLLGSLFGSKRGKPP---------PQAHLPSAPALPPPHPPVV 1000

Query: 399  HKKHKHRAKESQQGCRGLQAPLASGGPVLGREHLRELPALVVYESQAGQPVQRHEHHH-- 456
                +H       G        A  G      H++  P           P   H HHH  
Sbjct: 1001 LPHLQHSVAGHHLGPPEGLPQAAMHGHHTQYCHMQNPP-----------PYHHHHHHHPP 1049

Query: 457  -HHEHHHHYHH 466
             H +H H YHH
Sbjct: 1050 QHIQHAHQYHH 1060


>gi|148762982 hypothetical protein LOC387640 [Homo sapiens]
          Length = 908

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 12/15 (80%), Positives = 13/15 (86%)

Query: 452 HEHHHHHEHHHHYHH 466
           H HHHHH HHHH+HH
Sbjct: 337 HHHHHHHHHHHHHHH 351



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 12/18 (66%), Positives = 13/18 (72%)

Query: 448 PVQRHEHHHHHEHHHHYH 465
           P   H HHHHH HHHH+H
Sbjct: 334 PPPHHHHHHHHHHHHHHH 351



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 11/16 (68%), Positives = 14/16 (87%)

Query: 454 HHHHHEHHHHYHHFYQ 469
           HHHHH HHHH+HH ++
Sbjct: 337 HHHHHHHHHHHHHHHR 352


>gi|61966923 forkhead box B2 [Homo sapiens]
          Length = 432

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 14/22 (63%), Positives = 15/22 (68%)

Query: 445 AGQPVQRHEHHHHHEHHHHYHH 466
           AG     H HHHHH HHHH+HH
Sbjct: 130 AGPGGHLHPHHHHHPHHHHHHH 151



 Score = 37.0 bits (84), Expect = 0.039
 Identities = 12/17 (70%), Positives = 13/17 (76%), Gaps = 2/17 (11%)

Query: 452 HEHHHHHE--HHHHYHH 466
           H HHHHH   HHHH+HH
Sbjct: 145 HHHHHHHAAAHHHHHHH 161



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 12/24 (50%), Positives = 14/24 (58%), Gaps = 3/24 (12%)

Query: 448 PVQRHEHHHHHEHH---HHYHHFY 468
           P   H  HHHH HH   HH+HH +
Sbjct: 138 PHHHHHPHHHHHHHAAAHHHHHHH 161



 Score = 33.9 bits (76), Expect = 0.33
 Identities = 10/17 (58%), Positives = 12/17 (70%)

Query: 452 HEHHHHHEHHHHYHHFY 468
           H H HHH H HH+HH +
Sbjct: 135 HLHPHHHHHPHHHHHHH 151


>gi|84105335 mesenchyme homeobox 2 [Homo sapiens]
          Length = 304

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 15/31 (48%), Positives = 19/31 (61%), Gaps = 2/31 (6%)

Query: 441 YESQAGQPVQRHE--HHHHHEHHHHYHHFYQ 469
           Y ++ G    +H   HHHHH HHHH+HH  Q
Sbjct: 53  YPNEEGMFASQHHRGHHHHHHHHHHHHHQQQ 83



 Score = 36.6 bits (83), Expect = 0.050
 Identities = 11/18 (61%), Positives = 12/18 (66%)

Query: 452 HEHHHHHEHHHHYHHFYQ 469
           H HHHHH HHHH    +Q
Sbjct: 69  HHHHHHHHHHHHQQQQHQ 86



 Score = 33.5 bits (75), Expect = 0.43
 Identities = 11/27 (40%), Positives = 14/27 (51%)

Query: 440 VYESQAGQPVQRHEHHHHHEHHHHYHH 466
           ++ SQ  +    H HHHHH HH    H
Sbjct: 59  MFASQHHRGHHHHHHHHHHHHHQQQQH 85



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 10/19 (52%), Positives = 10/19 (52%)

Query: 452 HEHHHHHEHHHHYHHFYQT 470
           H HHHHH H    H   QT
Sbjct: 72  HHHHHHHHHQQQQHQALQT 90


>gi|192447423 frequenin homolog isoform 2 [Homo sapiens]
          Length = 172

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 15/39 (38%), Positives = 26/39 (66%)

Query: 133 DSRQEWTFTLYDFDNNGKVTREDITSLLHTIYEVVDSSV 171
           D +  W F LYD DN+G +TR ++  ++  IY++V ++V
Sbjct: 80  DEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGNTV 118


>gi|17738308 frequenin homolog isoform 1 [Homo sapiens]
          Length = 190

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 15/39 (38%), Positives = 26/39 (66%)

Query: 133 DSRQEWTFTLYDFDNNGKVTREDITSLLHTIYEVVDSSV 171
           D +  W F LYD DN+G +TR ++  ++  IY++V ++V
Sbjct: 98  DEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGNTV 136


>gi|27894361 nuclear receptor subfamily 4, group A, member 3 isoform
           b [Homo sapiens]
          Length = 637

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 16/34 (47%), Positives = 20/34 (58%), Gaps = 2/34 (5%)

Query: 436 PALVVYESQAGQPVQRHEHHHHHEHHHHYHHFYQ 469
           P + V E +A  P   H HHHHH HHHH+   +Q
Sbjct: 93  PLIKVEEGRA--PSYHHHHHHHHHHHHHHQQQHQ 124



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 17/39 (43%), Positives = 20/39 (51%), Gaps = 7/39 (17%)

Query: 434 ELPALVVYESQA-------GQPVQRHEHHHHHEHHHHYH 465
           EL    VY+ Q        G+    H HHHHH HHHH+H
Sbjct: 81  ELKPSCVYQMQRPLIKVEEGRAPSYHHHHHHHHHHHHHH 119



 Score = 37.4 bits (85), Expect = 0.030
 Identities = 13/32 (40%), Positives = 14/32 (43%)

Query: 438 LVVYESQAGQPVQRHEHHHHHEHHHHYHHFYQ 469
           L+  E         H HHHHH HHHH     Q
Sbjct: 94  LIKVEEGRAPSYHHHHHHHHHHHHHHQQQHQQ 125


>gi|27894359 nuclear receptor subfamily 4, group A, member 3 isoform
           c [Homo sapiens]
          Length = 443

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 16/34 (47%), Positives = 20/34 (58%), Gaps = 2/34 (5%)

Query: 436 PALVVYESQAGQPVQRHEHHHHHEHHHHYHHFYQ 469
           P + V E +A  P   H HHHHH HHHH+   +Q
Sbjct: 82  PLIKVEEGRA--PSYHHHHHHHHHHHHHHQQQHQ 113



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 17/39 (43%), Positives = 20/39 (51%), Gaps = 7/39 (17%)

Query: 434 ELPALVVYESQA-------GQPVQRHEHHHHHEHHHHYH 465
           EL    VY+ Q        G+    H HHHHH HHHH+H
Sbjct: 70  ELKPSCVYQMQRPLIKVEEGRAPSYHHHHHHHHHHHHHH 108



 Score = 37.4 bits (85), Expect = 0.030
 Identities = 13/32 (40%), Positives = 14/32 (43%)

Query: 438 LVVYESQAGQPVQRHEHHHHHEHHHHYHHFYQ 469
           L+  E         H HHHHH HHHH     Q
Sbjct: 83  LIKVEEGRAPSYHHHHHHHHHHHHHHQQQHQQ 114


>gi|27894357 nuclear receptor subfamily 4, group A, member 3 isoform
           a [Homo sapiens]
          Length = 626

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 16/34 (47%), Positives = 20/34 (58%), Gaps = 2/34 (5%)

Query: 436 PALVVYESQAGQPVQRHEHHHHHEHHHHYHHFYQ 469
           P + V E +A  P   H HHHHH HHHH+   +Q
Sbjct: 82  PLIKVEEGRA--PSYHHHHHHHHHHHHHHQQQHQ 113



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 17/39 (43%), Positives = 20/39 (51%), Gaps = 7/39 (17%)

Query: 434 ELPALVVYESQA-------GQPVQRHEHHHHHEHHHHYH 465
           EL    VY+ Q        G+    H HHHHH HHHH+H
Sbjct: 70  ELKPSCVYQMQRPLIKVEEGRAPSYHHHHHHHHHHHHHH 108



 Score = 37.4 bits (85), Expect = 0.030
 Identities = 13/32 (40%), Positives = 14/32 (43%)

Query: 438 LVVYESQAGQPVQRHEHHHHHEHHHHYHHFYQ 469
           L+  E         H HHHHH HHHH     Q
Sbjct: 83  LIKVEEGRAPSYHHHHHHHHHHHHHHQQQHQQ 114


>gi|27894355 nuclear receptor subfamily 4, group A, member 3 isoform
           a [Homo sapiens]
          Length = 626

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 16/34 (47%), Positives = 20/34 (58%), Gaps = 2/34 (5%)

Query: 436 PALVVYESQAGQPVQRHEHHHHHEHHHHYHHFYQ 469
           P + V E +A  P   H HHHHH HHHH+   +Q
Sbjct: 82  PLIKVEEGRA--PSYHHHHHHHHHHHHHHQQQHQ 113



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 17/39 (43%), Positives = 20/39 (51%), Gaps = 7/39 (17%)

Query: 434 ELPALVVYESQA-------GQPVQRHEHHHHHEHHHHYH 465
           EL    VY+ Q        G+    H HHHHH HHHH+H
Sbjct: 70  ELKPSCVYQMQRPLIKVEEGRAPSYHHHHHHHHHHHHHH 108



 Score = 37.4 bits (85), Expect = 0.030
 Identities = 13/32 (40%), Positives = 14/32 (43%)

Query: 438 LVVYESQAGQPVQRHEHHHHHEHHHHYHHFYQ 469
           L+  E         H HHHHH HHHH     Q
Sbjct: 83  LIKVEEGRAPSYHHHHHHHHHHHHHHQQQHQQ 114


>gi|21361559 visinin-like 1 [Homo sapiens]
          Length = 191

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 16/57 (28%), Positives = 32/57 (56%), Gaps = 4/57 (7%)

Query: 119 LKFEELQCDVSMEE----DSRQEWTFTLYDFDNNGKVTREDITSLLHTIYEVVDSSV 171
           + F E  C +S+      + +  W F +YD D +GK+TR ++  ++  IY++V + +
Sbjct: 80  IDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVEMLEIIEAIYKMVGTVI 136


>gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo
            sapiens]
          Length = 2506

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 48/220 (21%), Positives = 85/220 (38%), Gaps = 31/220 (14%)

Query: 269  TSQFGPGSPSVAQKSELPPRTSNPTRSRSH--EPEAIHIPHRKPQGVDPASFHFLDTPIA 326
            ++Q  PG   +A +S L    S  T+      +      P + P    P S      P +
Sbjct: 2008 STQLDPGGALMAHESGLKESPSWVTQRAQEMFQKTGTWSPEQGPPTDMPNS-----QPNS 2062

Query: 327  KVSELQQRLRGTQDGSKHFVRSPKAQGKSVGVGHVA--RGARNKPPLGPAIPAVSPSAHL 384
            +  E+++  R     S+H++   + QG++  +  +      R   P G  +  +S ++ +
Sbjct: 2063 QSVEMREMGRDGYSDSEHYLPM-EGQGRAASMPRLPAENQRRRGRPRGNNLSTISDTSPM 2121

Query: 385  AASPALLPSLA------------PLGHKKH-------KHRAKESQQGCRGLQAPLASGGP 425
              S ++L   A            P  +++H        HRA E   G R        G  
Sbjct: 2122 KRSASVLGPKARRLDDYSLERVPPEENQRHHQRRRDRSHRASERSLG-RYTDVDTGLGTD 2180

Query: 426  VLGREHLRELPALVVYESQAGQPVQRHEHHHHHEHHHHYH 465
            +       +LP+    + + G+P  R    HHH HHHH+H
Sbjct: 2181 LSMTTQSGDLPSKE-RDQERGRPKDRKHRQHHHHHHHHHH 2219


>gi|187828880 calcium channel, alpha 1A subunit isoform 3 [Homo
            sapiens]
          Length = 2261

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 48/220 (21%), Positives = 85/220 (38%), Gaps = 31/220 (14%)

Query: 269  TSQFGPGSPSVAQKSELPPRTSNPTRSRSH--EPEAIHIPHRKPQGVDPASFHFLDTPIA 326
            ++Q  PG   +A +S L    S  T+      +      P + P    P S      P +
Sbjct: 2009 STQLDPGGALMAHESGLKESPSWVTQRAQEMFQKTGTWSPEQGPPTDMPNS-----QPNS 2063

Query: 327  KVSELQQRLRGTQDGSKHFVRSPKAQGKSVGVGHVA--RGARNKPPLGPAIPAVSPSAHL 384
            +  E+++  R     S+H++   + QG++  +  +      R   P G  +  +S ++ +
Sbjct: 2064 QSVEMREMGRDGYSDSEHYLPM-EGQGRAASMPRLPAENQRRRGRPRGNNLSTISDTSPM 2122

Query: 385  AASPALLPSLA------------PLGHKKH-------KHRAKESQQGCRGLQAPLASGGP 425
              S ++L   A            P  +++H        HRA E   G R        G  
Sbjct: 2123 KRSASVLGPKARRLDDYSLERVPPEENQRHHQRRRDRSHRASERSLG-RYTDVDTGLGTD 2181

Query: 426  VLGREHLRELPALVVYESQAGQPVQRHEHHHHHEHHHHYH 465
            +       +LP+    + + G+P  R    HHH HHHH+H
Sbjct: 2182 LSMTTQSGDLPSKE-RDQERGRPKDRKHRQHHHHHHHHHH 2220


>gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 1A isoform 2 [Homo sapiens]
          Length = 754

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 12/16 (75%), Positives = 13/16 (81%)

Query: 454 HHHHHEHHHHYHHFYQ 469
           HHHHH HHHH+HH  Q
Sbjct: 598 HHHHHHHHHHHHHGQQ 613



 Score = 36.2 bits (82), Expect = 0.066
 Identities = 10/13 (76%), Positives = 11/13 (84%)

Query: 452 HEHHHHHEHHHHY 464
           H HHHHH HHHH+
Sbjct: 598 HHHHHHHHHHHHH 610



 Score = 35.8 bits (81), Expect = 0.086
 Identities = 18/47 (38%), Positives = 21/47 (44%), Gaps = 12/47 (25%)

Query: 434 ELPALVVYESQAGQ-------PVQRHEHHHH-----HEHHHHYHHFY 468
           E P  V  E+   Q       P Q   HHHH     H HHHH+HH +
Sbjct: 563 EAPTQVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHH 609



 Score = 33.5 bits (75), Expect = 0.43
 Identities = 10/17 (58%), Positives = 10/17 (58%)

Query: 446 GQPVQRHEHHHHHEHHH 462
           G     H HHHHH HHH
Sbjct: 594 GNSSHHHHHHHHHHHHH 610


>gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 1A isoform 1 [Homo sapiens]
          Length = 763

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 12/16 (75%), Positives = 13/16 (81%)

Query: 454 HHHHHEHHHHYHHFYQ 469
           HHHHH HHHH+HH  Q
Sbjct: 607 HHHHHHHHHHHHHGQQ 622



 Score = 36.2 bits (82), Expect = 0.066
 Identities = 10/13 (76%), Positives = 11/13 (84%)

Query: 452 HEHHHHHEHHHHY 464
           H HHHHH HHHH+
Sbjct: 607 HHHHHHHHHHHHH 619



 Score = 35.8 bits (81), Expect = 0.086
 Identities = 18/47 (38%), Positives = 21/47 (44%), Gaps = 12/47 (25%)

Query: 434 ELPALVVYESQAGQ-------PVQRHEHHHH-----HEHHHHYHHFY 468
           E P  V  E+   Q       P Q   HHHH     H HHHH+HH +
Sbjct: 572 EAPTQVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHH 618



 Score = 33.5 bits (75), Expect = 0.43
 Identities = 10/17 (58%), Positives = 10/17 (58%)

Query: 446 GQPVQRHEHHHHHEHHH 462
           G     H HHHHH HHH
Sbjct: 603 GNSSHHHHHHHHHHHHH 619


>gi|19913446 hippocalcin [Homo sapiens]
          Length = 193

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 18/55 (32%), Positives = 31/55 (56%), Gaps = 4/55 (7%)

Query: 119 LKFEELQCDVSMEEDSRQE----WTFTLYDFDNNGKVTREDITSLLHTIYEVVDS 169
           + F E    +S+    R E    W F++YD D NG ++RE++  ++  IY++V S
Sbjct: 80  IDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSS 134


>gi|40288197 GATA binding protein 6 [Homo sapiens]
          Length = 595

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 34/114 (29%), Positives = 43/114 (37%), Gaps = 11/114 (9%)

Query: 351 AQGKSVGVGHVARGARNKPPLGPAIPAVSPSAHLAASPALLPSLAPLGHKKHKHRAKESQ 410
           A     G G  A G     P G    A   SA    SP+  P +A    ++    A    
Sbjct: 230 ADSPPYGSGGGAAGGGAAGPGGAGSAAAHVSARFPYSPS--PPMANGAAREPGGYAAAGS 287

Query: 411 QGCRGLQAPLASGGPVLGREHLRELPALVVYES-QAGQPVQRHEHHHHHEHHHH 463
            G  G+    +S   + GRE          Y S  A +P+    HHHHH HHHH
Sbjct: 288 GGAGGVSGGGSSLAAMGGREPQ--------YSSLSAARPLNGTYHHHHHHHHHH 333


>gi|55770830 chromobox homolog 4 [Homo sapiens]
          Length = 560

 Score = 38.9 bits (89), Expect = 0.010
 Identities = 11/14 (78%), Positives = 12/14 (85%)

Query: 452 HEHHHHHEHHHHYH 465
           H HHHHH HHHH+H
Sbjct: 387 HPHHHHHHHHHHHH 400



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 13/22 (59%), Positives = 14/22 (63%), Gaps = 3/22 (13%)

Query: 448 PVQRHEH---HHHHEHHHHYHH 466
           P   H H   HHHH HHHH+HH
Sbjct: 379 PPSHHPHPHPHHHHHHHHHHHH 400



 Score = 32.7 bits (73), Expect = 0.73
 Identities = 11/33 (33%), Positives = 16/33 (48%)

Query: 436 PALVVYESQAGQPVQRHEHHHHHEHHHHYHHFY 468
           P L+ ++         H  H H  HHHH+HH +
Sbjct: 366 PDLLAWDPARNTHPPSHHPHPHPHHHHHHHHHH 398


>gi|122937233 discs, large (Drosophila) homolog-associated protein 3
           [Homo sapiens]
          Length = 979

 Score = 38.5 bits (88), Expect = 0.013
 Identities = 11/15 (73%), Positives = 12/15 (80%)

Query: 452 HEHHHHHEHHHHYHH 466
           H  HHHH HHHH+HH
Sbjct: 220 HTSHHHHHHHHHHHH 234



 Score = 38.1 bits (87), Expect = 0.017
 Identities = 12/19 (63%), Positives = 13/19 (68%)

Query: 445 AGQPVQRHEHHHHHEHHHH 463
           +G P   H HHHHH HHHH
Sbjct: 216 SGGPHTSHHHHHHHHHHHH 234



 Score = 35.8 bits (81), Expect = 0.086
 Identities = 11/21 (52%), Positives = 11/21 (52%)

Query: 446 GQPVQRHEHHHHHEHHHHYHH 466
           G     H HHHHH HHH   H
Sbjct: 218 GPHTSHHHHHHHHHHHHQSRH 238



 Score = 34.7 bits (78), Expect = 0.19
 Identities = 10/17 (58%), Positives = 13/17 (76%)

Query: 454 HHHHHEHHHHYHHFYQT 470
           H  HH HHHH+HH +Q+
Sbjct: 220 HTSHHHHHHHHHHHHQS 236


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,506,070
Number of Sequences: 37866
Number of extensions: 1122498
Number of successful extensions: 6339
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 152
Number of HSP's successfully gapped in prelim test: 88
Number of HSP's that attempted gapping in prelim test: 4423
Number of HSP's gapped (non-prelim): 929
length of query: 470
length of database: 18,247,518
effective HSP length: 106
effective length of query: 364
effective length of database: 14,233,722
effective search space: 5181074808
effective search space used: 5181074808
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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