BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|93004092 nuclear factor I/B [Homo sapiens] (420 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|93004092 nuclear factor I/B [Homo sapiens] 875 0.0 gi|45505149 nuclear factor I/C isoform 1 [Homo sapiens] 528 e-150 gi|224465184 nuclear factor I/A isoform 4 [Homo sapiens] 502 e-142 gi|45505151 nuclear factor I/C isoform 2 [Homo sapiens] 502 e-142 gi|30840980 nuclear factor I/A isoform 2 [Homo sapiens] 502 e-142 gi|197927284 nuclear factor I/A isoform 1 [Homo sapiens] 502 e-142 gi|224465182 nuclear factor I/A isoform 3 [Homo sapiens] 483 e-136 gi|56549649 nuclear factor I/X (CCAAT-binding transcription fact... 467 e-131 gi|50345881 cytoplasmic polyadenylation element binding protein ... 46 6e-05 gi|50345997 E1A binding protein p300 [Homo sapiens] 46 7e-05 gi|238859651 pleckstrin homology domain containing family A memb... 44 4e-04 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 44 4e-04 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 44 4e-04 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 44 4e-04 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 44 4e-04 gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 44 4e-04 gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 43 6e-04 gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 43 6e-04 gi|19923345 RNA binding motif protein 12 [Homo sapiens] 43 6e-04 gi|23510462 RNA binding motif protein 12 [Homo sapiens] 43 6e-04 gi|46852390 coiled-coil domain containing 6 [Homo sapiens] 43 6e-04 gi|11386183 WAS protein family, member 2 [Homo sapiens] 42 8e-04 gi|151301154 mucin 6, gastric [Homo sapiens] 42 8e-04 gi|40788007 FYN binding protein (FYB-120/130) isoform 2 [Homo sa... 42 8e-04 gi|42476118 FYN binding protein (FYB-120/130) isoform 1 [Homo sa... 42 8e-04 gi|150170729 microtubule associated serine/threonine kinase 3 [H... 42 8e-04 gi|28558973 mediator complex subunit 14 [Homo sapiens] 42 0.001 gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens] 42 0.001 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 41 0.002 gi|116875765 tight junction protein 1 isoform b [Homo sapiens] 41 0.002 >gi|93004092 nuclear factor I/B [Homo sapiens] Length = 420 Score = 875 bits (2262), Expect = 0.0 Identities = 420/420 (100%), Positives = 420/420 (100%) Query: 1 MMYSPICLTQDEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDE 60 MMYSPICLTQDEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDE Sbjct: 1 MMYSPICLTQDEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDE 60 Query: 61 LLSEKPEIKQKWASRLLAKLRKDIRQEYREDFVLTVTGKKHPCCVLSNPDQKGKIRRIDC 120 LLSEKPEIKQKWASRLLAKLRKDIRQEYREDFVLTVTGKKHPCCVLSNPDQKGKIRRIDC Sbjct: 61 LLSEKPEIKQKWASRLLAKLRKDIRQEYREDFVLTVTGKKHPCCVLSNPDQKGKIRRIDC 120 Query: 121 LRQADKVWRLDLVMVILFKGIPLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFL 180 LRQADKVWRLDLVMVILFKGIPLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFL Sbjct: 121 LRQADKVWRLDLVMVILFKGIPLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFL 180 Query: 181 AYYVQEQDSGQSGSPSHNDPAKNPPGYLEDSFVKSGVFNVSELVRVSRTPITQGTGVNFP 240 AYYVQEQDSGQSGSPSHNDPAKNPPGYLEDSFVKSGVFNVSELVRVSRTPITQGTGVNFP Sbjct: 181 AYYVQEQDSGQSGSPSHNDPAKNPPGYLEDSFVKSGVFNVSELVRVSRTPITQGTGVNFP 240 Query: 241 IGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGS 300 IGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGS Sbjct: 241 IGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGS 300 Query: 301 RTWHERDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTP 360 RTWHERDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTP Sbjct: 301 RTWHERDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTP 360 Query: 361 PPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQTSQSWYLG 420 PPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQTSQSWYLG Sbjct: 361 PPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQTSQSWYLG 420 >gi|45505149 nuclear factor I/C isoform 1 [Homo sapiens] Length = 428 Score = 528 bits (1361), Expect = e-150 Identities = 280/432 (64%), Positives = 329/432 (76%), Gaps = 16/432 (3%) Query: 1 MMYSPICLTQDEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDE 60 M SP+CLTQDEFHPFIEALLPHVRA AYTWFNLQARKRKYFKKHEKRMSKDEERAVKDE Sbjct: 1 MYSSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDE 60 Query: 61 LLSEKPEIKQKWASRLLAKLRKDIRQEYREDFVLTVTGKKHPCCVLSNPDQKGKIRRIDC 120 LL EKPE+KQKWASRLLAKLRKDIR E REDFVL++TGKK P CVLSNPDQKGK+RRIDC Sbjct: 61 LLGEKPEVKQKWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDC 120 Query: 121 LRQADKVWRLDLVMVILFKGIPLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFL 180 LRQADKVWRLDLVMVILFKGIPLESTDGERL+K+ C +P LCVQPHHI V+VKELDL+L Sbjct: 121 LRQADKVWRLDLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYL 180 Query: 181 AYYVQEQDSGQSGSP---SHNDPAKNPPGYL-----EDSFVKSGVFNVSELVRVSRTPIT 232 AY+V+E+D+ QSGSP +D + P L ++SFV SGVF+V+EL++VSRTP+ Sbjct: 181 AYFVRERDAEQSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVV 240 Query: 233 QGTGVNFPIGEIPSQPYYHDMNSGVNLQRSLSSPPS--SKRPKTISIDENMEPSPTGDFY 290 GTG NF +GE+ Y + L+R+L S S SKR K+ S++E+++ SP GD+Y Sbjct: 241 TGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYY 300 Query: 291 PSPSSPAAGSRTWHE-RDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPG 349 SPSSP + SR W E + +SSP + +K F+S SPQD SPRLS+F QHH P I Sbjct: 301 TSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQD-SPRLSSFTQHHRPVI-- 357 Query: 350 VAHSVISTRTPPPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVP-SYDP 408 HS I+ R+P P S L FPT +ILP S+YF H IRYPPHLNPQD LK+ V + DP Sbjct: 358 AVHSGIA-RSPHPSSALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDP 416 Query: 409 SSPQTSQSWYLG 420 +S Q SWYLG Sbjct: 417 ASQQPGPSWYLG 428 >gi|224465184 nuclear factor I/A isoform 4 [Homo sapiens] Length = 554 Score = 502 bits (1293), Expect = e-142 Identities = 274/422 (64%), Positives = 314/422 (74%), Gaps = 22/422 (5%) Query: 1 MMYSPICLTQDEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDE 60 +MYSP+CLTQDEFHPFIEALLPHVRA AYTWFNLQARKRKYFKKHEKRMSK+EERAVKDE Sbjct: 45 VMYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDE 104 Query: 61 LLSEKPEIKQKWASRLLAKLRKDIRQEYREDFVLTVTGKKHPCCVLSNPDQKGKIRRIDC 120 LLSEKPE+KQKWASRLLAKLRKDIR EYREDFVLTVTGKK PCCVLSNPDQKGK+RRIDC Sbjct: 105 LLSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDC 164 Query: 121 LRQADKVWRLDLVMVILFKGIPLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFL 180 LRQADKVWRLDLVMVILFKGIPLESTDGERL+KSP C+NP LCVQPHHI VSVKELDL+L Sbjct: 165 LRQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYL 224 Query: 181 AYYVQEQDSGQSGSPSHNDPA--KNPP--GYL--EDSFVKSGVFNVSELVRVSRTPITQG 234 AY+V DS QS SPS A K+ P G+L +DSFV SGVF+V+ELVRVS+TPI G Sbjct: 225 AYFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAG 284 Query: 235 TGVNFPIGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTI-SIDENMEPSPTGDFYPSP 293 TG NF + ++ S YY M+ G ++RSL S S+ K + S+++ M+ FY Sbjct: 285 TGPNFSLSDLESSSYY-SMSPGA-MRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQ 342 Query: 294 S-SPAAGSRT--WHERDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGV 350 SP +GS++ WHE + M SPTT+KK EK FSS SP +S + F QHH P I G Sbjct: 343 GRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGP 402 Query: 351 AHSVISTRTPPPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSS 410 S +T PS L FPT I+ P YFSHP IRY +PQ+TLK +V P + Sbjct: 403 RASPHAT-----PSTLHFPTSPII-QQPGPYFSHPAIRY----HPQETLKEFVQLVCPDA 452 Query: 411 PQ 412 Q Sbjct: 453 GQ 454 >gi|45505151 nuclear factor I/C isoform 2 [Homo sapiens] Length = 499 Score = 502 bits (1293), Expect = e-142 Identities = 268/414 (64%), Positives = 316/414 (76%), Gaps = 16/414 (3%) Query: 11 DEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLSEKPEIKQ 70 DEFHPFIEALLPHVRA AYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELL EKPE+KQ Sbjct: 2 DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVKQ 61 Query: 71 KWASRLLAKLRKDIRQEYREDFVLTVTGKKHPCCVLSNPDQKGKIRRIDCLRQADKVWRL 130 KWASRLLAKLRKDIR E REDFVL++TGKK P CVLSNPDQKGK+RRIDCLRQADKVWRL Sbjct: 62 KWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWRL 121 Query: 131 DLVMVILFKGIPLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFLAYYVQEQDSG 190 DLVMVILFKGIPLESTDGERL+K+ C +P LCVQPHHI V+VKELDL+LAY+V+E+D+ Sbjct: 122 DLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDAE 181 Query: 191 QSGSP---SHNDPAKNPPGYL-----EDSFVKSGVFNVSELVRVSRTPITQGTGVNFPIG 242 QSGSP +D + P L ++SFV SGVF+V+EL++VSRTP+ GTG NF +G Sbjct: 182 QSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLG 241 Query: 243 EIPSQPYYHDMNSGVNLQRSLSSPPS--SKRPKTISIDENMEPSPTGDFYPSPSSPAAGS 300 E+ Y + L+R+L S S SKR K+ S++E+++ SP GD+Y SPSSP + S Sbjct: 242 ELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSS 301 Query: 301 RTWHE-RDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRT 359 R W E + +SSP + +K F+S SPQD SPRLS+F QHH P I HS I+ R+ Sbjct: 302 RNWTEDMEGGISSPVKKTEMDKSPFNSPSPQD-SPRLSSFTQHHRPVI--AVHSGIA-RS 357 Query: 360 PPPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVP-SYDPSSPQ 412 P P S L FPT +ILP S+YF H IRYPPHLNPQD LK+ V + DP+S Q Sbjct: 358 PHPSSALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQ 411 >gi|30840980 nuclear factor I/A isoform 2 [Homo sapiens] Length = 498 Score = 502 bits (1292), Expect = e-142 Identities = 274/421 (65%), Positives = 313/421 (74%), Gaps = 22/421 (5%) Query: 2 MYSPICLTQDEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDEL 61 MYSP+CLTQDEFHPFIEALLPHVRA AYTWFNLQARKRKYFKKHEKRMSK+EERAVKDEL Sbjct: 1 MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 60 Query: 62 LSEKPEIKQKWASRLLAKLRKDIRQEYREDFVLTVTGKKHPCCVLSNPDQKGKIRRIDCL 121 LSEKPE+KQKWASRLLAKLRKDIR EYREDFVLTVTGKK PCCVLSNPDQKGK+RRIDCL Sbjct: 61 LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 120 Query: 122 RQADKVWRLDLVMVILFKGIPLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFLA 181 RQADKVWRLDLVMVILFKGIPLESTDGERL+KSP C+NP LCVQPHHI VSVKELDL+LA Sbjct: 121 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 180 Query: 182 YYVQEQDSGQSGSPSHNDPA--KNPP--GYL--EDSFVKSGVFNVSELVRVSRTPITQGT 235 Y+V DS QS SPS A K+ P G+L +DSFV SGVF+V+ELVRVS+TPI GT Sbjct: 181 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 240 Query: 236 GVNFPIGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTI-SIDENMEPSPTGDFYPSPS 294 G NF + ++ S YY M+ G ++RSL S S+ K + S+++ M+ FY Sbjct: 241 GPNFSLSDLESSSYY-SMSPGA-MRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQG 298 Query: 295 -SPAAGSRT--WHERDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGVA 351 SP +GS++ WHE + M SPTT+KK EK FSS SP +S + F QHH P I G Sbjct: 299 RSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR 358 Query: 352 HSVISTRTPPPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSP 411 S +T PS L FPT I+ P YFSHP IRY +PQ+TLK +V P + Sbjct: 359 ASPHAT-----PSTLHFPTSPII-QQPGPYFSHPAIRY----HPQETLKEFVQLVCPDAG 408 Query: 412 Q 412 Q Sbjct: 409 Q 409 >gi|197927284 nuclear factor I/A isoform 1 [Homo sapiens] Length = 509 Score = 502 bits (1292), Expect = e-142 Identities = 274/421 (65%), Positives = 313/421 (74%), Gaps = 22/421 (5%) Query: 2 MYSPICLTQDEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDEL 61 MYSP+CLTQDEFHPFIEALLPHVRA AYTWFNLQARKRKYFKKHEKRMSK+EERAVKDEL Sbjct: 1 MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 60 Query: 62 LSEKPEIKQKWASRLLAKLRKDIRQEYREDFVLTVTGKKHPCCVLSNPDQKGKIRRIDCL 121 LSEKPE+KQKWASRLLAKLRKDIR EYREDFVLTVTGKK PCCVLSNPDQKGK+RRIDCL Sbjct: 61 LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 120 Query: 122 RQADKVWRLDLVMVILFKGIPLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFLA 181 RQADKVWRLDLVMVILFKGIPLESTDGERL+KSP C+NP LCVQPHHI VSVKELDL+LA Sbjct: 121 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 180 Query: 182 YYVQEQDSGQSGSPSHNDPA--KNPP--GYL--EDSFVKSGVFNVSELVRVSRTPITQGT 235 Y+V DS QS SPS A K+ P G+L +DSFV SGVF+V+ELVRVS+TPI GT Sbjct: 181 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 240 Query: 236 GVNFPIGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTI-SIDENMEPSPTGDFYPSPS 294 G NF + ++ S YY M+ G ++RSL S S+ K + S+++ M+ FY Sbjct: 241 GPNFSLSDLESSSYY-SMSPGA-MRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQG 298 Query: 295 -SPAAGSRT--WHERDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGVA 351 SP +GS++ WHE + M SPTT+KK EK FSS SP +S + F QHH P I G Sbjct: 299 RSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR 358 Query: 352 HSVISTRTPPPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSP 411 S +T PS L FPT I+ P YFSHP IRY +PQ+TLK +V P + Sbjct: 359 ASPHAT-----PSTLHFPTSPII-QQPGPYFSHPAIRY----HPQETLKEFVQLVCPDAG 408 Query: 412 Q 412 Q Sbjct: 409 Q 409 >gi|224465182 nuclear factor I/A isoform 3 [Homo sapiens] Length = 501 Score = 483 bits (1244), Expect = e-136 Identities = 266/412 (64%), Positives = 304/412 (73%), Gaps = 22/412 (5%) Query: 11 DEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLSEKPEIKQ 70 DEFHPFIEALLPHVRA AYTWFNLQARKRKYFKKHEKRMSK+EERAVKDELLSEKPE+KQ Sbjct: 2 DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ 61 Query: 71 KWASRLLAKLRKDIRQEYREDFVLTVTGKKHPCCVLSNPDQKGKIRRIDCLRQADKVWRL 130 KWASRLLAKLRKDIR EYREDFVLTVTGKK PCCVLSNPDQKGK+RRIDCLRQADKVWRL Sbjct: 62 KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL 121 Query: 131 DLVMVILFKGIPLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFLAYYVQEQDSG 190 DLVMVILFKGIPLESTDGERL+KSP C+NP LCVQPHHI VSVKELDL+LAY+V DS Sbjct: 122 DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS 181 Query: 191 QSGSPSHNDPA--KNPP--GYL--EDSFVKSGVFNVSELVRVSRTPITQGTGVNFPIGEI 244 QS SPS A K+ P G+L +DSFV SGVF+V+ELVRVS+TPI GTG NF + ++ Sbjct: 182 QSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDL 241 Query: 245 PSQPYYHDMNSGVNLQRSLSSPPSSKRPKTI-SIDENMEPSPTGDFYPSPS-SPAAGSRT 302 S YY M+ G ++RSL S S+ K + S+++ M+ FY SP +GS++ Sbjct: 242 ESSSYY-SMSPGA-MRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQS 299 Query: 303 --WHERDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTP 360 WHE + M SPTT+KK EK FSS SP +S + F QHH P I G S +T Sbjct: 300 SGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHAT--- 356 Query: 361 PPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQ 412 PS L FPT I+ P YFSHP IRY +PQ+TLK +V P + Q Sbjct: 357 --PSTLHFPTSPII-QQPGPYFSHPAIRY----HPQETLKEFVQLVCPDAGQ 401 >gi|56549649 nuclear factor I/X (CCAAT-binding transcription factor) [Homo sapiens] Length = 441 Score = 467 bits (1201), Expect = e-131 Identities = 264/414 (63%), Positives = 308/414 (74%), Gaps = 22/414 (5%) Query: 2 MYSPICLTQDEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDEL 61 MYSP CLTQDEFHPFIEALLPHVRA +YTWFNLQARKRKYFKKHEKRMSKDEERAVKDEL Sbjct: 1 MYSPYCLTQDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMSKDEERAVKDEL 60 Query: 62 LSEKPEIKQKWASRLLAKLRKDIRQEYREDFVLTVTGKKHPCCVLSNPDQKGKIRRIDCL 121 L EKPEIKQKWASRLLAKLRKDIR E+REDFVLT+TGKK PCCVLSNPDQKGKIRRIDCL Sbjct: 61 LGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCL 120 Query: 122 RQADKVWRLDLVMVILFKGIPLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFLA 181 RQADKVWRLDLVMVILFKGIPLESTDGERL KSP C+NP LCVQPHHI V++KELDL+LA Sbjct: 121 RQADKVWRLDLVMVILFKGIPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLA 180 Query: 182 YYVQEQDSGQSGSPSHNDPAKNPP---GYL--EDSFVKSGVFNVSELVRVSRTPITQGTG 236 Y+V +SGQS S + A P G+L +D FV SGV+NV+ELVRVS+TP+ +G Sbjct: 181 YFVHTPESGQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVRVSQTPVATASG 240 Query: 237 VNFPIGEIPSQPYYHDMNSGVNLQRSLSSPPS---SKRPKTISIDENMEPSPTGD-FYPS 292 NF + ++ S P Y+++N +RS++SPPS +KRPK SID++ SP D FYP Sbjct: 241 PNFSLADLES-PSYYNINQVTLGRRSITSPPSTSTTKRPK--SIDDSEMESPVDDVFYPG 297 Query: 293 PS-SPAAGSRTWHERDQDM-SSPTTMKKPEKPLFSSA-SPQDSSPRLSTFPQHHHPGIPG 349 SPAAGS D+ + P ++KK K F SA S Q SSPR++ F H P + G Sbjct: 298 TGRSPAAGSSQSSGWPNDVDAGPASLKKSGKLDFCSALSSQGSSPRMA-FTHHPLPVLAG 356 Query: 350 VAHSVISTRTPPPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYV 403 V S R S L FP+ +I+ + S YF+HPTIRY H + QD+LK +V Sbjct: 357 VRPG--SPRA--TASALHFPSTSIIQQS-SPYFTHPTIRYHHH-HGQDSLKEFV 404 >gi|50345881 cytoplasmic polyadenylation element binding protein 3 [Homo sapiens] Length = 698 Score = 46.2 bits (108), Expect = 6e-05 Identities = 38/153 (24%), Positives = 56/153 (36%), Gaps = 19/153 (12%) Query: 241 IGEIPSQPYYHDM-----NSGVNLQRSLSSPPSSKRPKTISIDENMEPSPTGDFY----- 290 + E PS P + NS V ++PP+ P + ++ + P + F+ Sbjct: 32 VSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLS--FHQPPQQ 89 Query: 291 -PSPSSPAAGSRTWHERDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPG 349 P P PAA + S T E F +P + + FP H +P G Sbjct: 90 PPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHVNPVFGG 149 Query: 350 VAHSVIST------RTPPPPSPLPFPTQAILPP 376 I + PPPP+P P P Q PP Sbjct: 150 TFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPP 182 >gi|50345997 E1A binding protein p300 [Homo sapiens] Length = 2414 Score = 45.8 bits (107), Expect = 7e-05 Identities = 51/196 (26%), Positives = 65/196 (33%), Gaps = 30/196 (15%) Query: 240 PIGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTISIDENMEPSPTGDFYPSPSSPAAG 299 PI + P H G Q +PP P+ +PS G F P P+ G Sbjct: 724 PIVPRQTPPLQHH---GQLAQPGALNPPMGYGPRM------QQPSNQGQFLPQTQFPSQG 774 Query: 300 SRTWH-----ERDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSV 354 + Q S M P+ S P S PQ P + + S Sbjct: 775 MNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSP 834 Query: 355 ISTRTPPP----PS-----------PLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTL 399 + +RTP P PS P P PT +PP P S HP R P P L Sbjct: 835 VPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTP-TPPTTQL 893 Query: 400 KNYVPSYDPSSPQTSQ 415 V P++P Q Sbjct: 894 PQQVQPSLPAAPSADQ 909 Score = 41.2 bits (95), Expect = 0.002 Identities = 46/205 (22%), Positives = 78/205 (38%), Gaps = 12/205 (5%) Query: 221 SELVRVSRTPITQGTGVNFPIGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTISIDEN 280 S+ + V+ P+ +G P+ + +NS + S S + ++ +N Sbjct: 772 SQGMNVTNIPLAPSSG-QAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQN 830 Query: 281 MEPSPTGDFYPSP--SSPAAGSRTWHERDQDMSSPTTMKKPEKPLFSSASP---QDSSPR 335 PSP P+P + P+ G++ PT P P + P Q +P Sbjct: 831 -SPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPP 889 Query: 336 LSTFPQHHHPGIPGVAHSVISTRTP----PPPSPLPFPTQAILPPAPSSYFSHPTIRYPP 391 + PQ P +P + + P + +P PT +LPP P++ S P + Sbjct: 890 TTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEG 949 Query: 392 HL-NPQDTLKNYVPSYDPSSPQTSQ 415 + NP T V S + Q SQ Sbjct: 950 QVSNPPSTSSTEVNSQAIAEKQPSQ 974 Score = 32.3 bits (72), Expect = 0.83 Identities = 39/172 (22%), Positives = 67/172 (38%), Gaps = 22/172 (12%) Query: 243 EIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRT 302 ++ Q H + L+R ++S +R + + + PSPT +P++P Sbjct: 1812 KLRQQQLQHRLQQAQMLRRRMAS---MQRTGVVGQQQGL-PSPTP---ATPTTPTG---- 1860 Query: 303 WHERDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPP 362 PTT + P+ +P +S P Q P G A ++ TPP Sbjct: 1861 --------QQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQ 1912 Query: 363 PS--PLPFPTQAILPPAPSSYFSHPTIRYPPHLNP-QDTLKNYVPSYDPSSP 411 + PLP P A + A + T R H+ Q +++ +P P +P Sbjct: 1913 TAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAP 1964 >gi|238859651 pleckstrin homology domain containing family A member 4 isoform 1 [Homo sapiens] Length = 779 Score = 43.5 bits (101), Expect = 4e-04 Identities = 55/208 (26%), Positives = 78/208 (37%), Gaps = 30/208 (14%) Query: 188 DSGQSGSPSHNDPAKNPPGYLEDSFVKSG-VFNVSELVRVSRTPITQGTGVNFPIGEIPS 246 D GQ SP+ P + P G V G +SE V+R +++G G + P+ Sbjct: 158 DYGQPRSPARPQPGEGPGGPGGPPEVSRGEEGRISESPEVTR--LSRGRGRPRLLTPSPT 215 Query: 247 QPYYHDMNSGVNLQRS--------LSSPPSS-KRPKTISIDENMEPSPTGDFYPSPSSPA 297 D++SG+ ++R+ LS PPS P+ S P+P+GD P Sbjct: 216 T----DLHSGLQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRPPAPSGDTAPPARPHT 271 Query: 298 AGSR-------TWHERDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGV 350 SR W + Q +S P T ++ P S PQH Sbjct: 272 PLSRIDVRPPLDWGPQRQTLSRPPTPRRGPPSEAGGGKPPRS-------PQHWSQEPRTQ 324 Query: 351 AHSVISTRTPPPPSPLPFPTQAILPPAP 378 AHS T PP P +L P P Sbjct: 325 AHSGSPTYLQLPPRPPGTRASMVLLPGP 352 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 43.5 bits (101), Expect = 4e-04 Identities = 34/106 (32%), Positives = 48/106 (45%), Gaps = 15/106 (14%) Query: 264 SSPPSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSSPTTMKKPEKPL 323 S P+ PK + EP+PT P+P++P T E +S+PTT K+P Sbjct: 681 SDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSE----VSTPTTTKEPTT-- 734 Query: 324 FSSASPQDSSPRLSTFPQ----HHHPGIPGVAHSVISTRTPPPPSP 365 SP +S+P LS P + P PGV +T+TP P Sbjct: 735 -IHKSPDESTPELSAEPTPKALENSPKEPGVP----TTKTPAATKP 775 Score = 43.1 bits (100), Expect = 5e-04 Identities = 37/156 (23%), Positives = 60/156 (38%), Gaps = 20/156 (12%) Query: 267 PSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSSPTTMKKPEKPLFSS 326 P+ PK + EP+PT P+P++P ++PTT+K+P Sbjct: 615 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG------------TAPTTLKEPAPTTPKK 662 Query: 327 ASPQDSSPRLSTFPQHHHPGIPG-VAHSVISTRTPPPPSPL----PFPTQAILPPAPSSY 381 +P++ +P + P P + TP P+P P PT PP +S Sbjct: 663 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSE 722 Query: 382 FSHPTIRYPP---HLNPQDTLKNYVPSYDPSSPQTS 414 S PT P H +P ++ P + + S Sbjct: 723 VSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENS 758 Score = 40.4 bits (93), Expect = 0.003 Identities = 38/149 (25%), Positives = 57/149 (38%), Gaps = 19/149 (12%) Query: 267 PSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHER--DQDMSSPTTMKKPEKPLF 324 P+ PK + EPSPT P+P++ + T E S+PTT K+P Sbjct: 364 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 423 Query: 325 SSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPPSPL-PFPTQAILPPAPSSYFS 383 +P T P+ P P + P P +P P PT PAP+ Sbjct: 424 KEPAPTTPKEPAPTTPKKPAPTTP---------KEPAPTTPKEPAPT-TTKKPAPT---- 469 Query: 384 HPTIRYPPHLNPQDTLKNYVPSYDPSSPQ 412 T + P P++T P++P+ Sbjct: 470 --TPKEPAPTTPKETAPTTPKKLTPTTPE 496 Score = 38.1 bits (87), Expect = 0.015 Identities = 41/177 (23%), Positives = 66/177 (37%), Gaps = 18/177 (10%) Query: 240 PIGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTISIDENMEPSPTGDFYPSPSSPAAG 299 P P +P + S + + + P T EP+PT P+P++P Sbjct: 224 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK-----EPAPTTTKEPAPTTPKEP 278 Query: 300 SRTWHER---DQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVIS 356 + T + S+PTT K+P +P T P+ P P + Sbjct: 279 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP--KEPAPT 336 Query: 357 TRTPPPPSPL-PFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQ 412 T+ P P +P P PT A PAP+ T + P P++ P++P+ Sbjct: 337 TKEPAPTTPKEPAPT-APKKPAPT------TPKEPAPTTPKEPAPTTTKEPSPTTPK 386 Score = 37.7 bits (86), Expect = 0.020 Identities = 38/153 (24%), Positives = 57/153 (37%), Gaps = 16/153 (10%) Query: 267 PSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHER----DQDMSSPTTMKKPEKP 322 P+ PK + +P+PT P+P++P + T ++ + +PTT +KP Sbjct: 450 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT 509 Query: 323 LFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPPSPL----PFPTQAILPPAP 378 +P T P+ P P A + TP P+P P PT P P Sbjct: 510 TPEELAPTTPEEPTPTTPEEPAPTTPKAA----APNTPKEPAPTTPKEPAPT---TPKEP 562 Query: 379 SSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSP 411 + T P TLK P+ P P Sbjct: 563 APTTPKETAPTTPKGTAPTTLKEPAPT-TPKKP 594 Score = 37.4 bits (85), Expect = 0.026 Identities = 36/157 (22%), Positives = 64/157 (40%), Gaps = 20/157 (12%) Query: 267 PSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSSPTTMKK-----PEK 321 P+ PK + EP+PT P+P++P + T E +PTT K+ P+K Sbjct: 301 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE-----PAPTTPKEPAPTAPKK 355 Query: 322 PLFSS------ASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPPSPLPFPTQAILP 375 P ++ +P++ +P + P P P + +T++ P + P PT Sbjct: 356 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP----APTTTKSAPTTTKEPAPTTTKSA 411 Query: 376 PAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQ 412 P S T + P P++ P++P+ Sbjct: 412 PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 448 Score = 37.0 bits (84), Expect = 0.034 Identities = 39/163 (23%), Positives = 64/163 (39%), Gaps = 20/163 (12%) Query: 267 PSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDM----SSPTTMKK---- 318 P+ PK + + EP+PT P+P++P + T + ++PTT+K+ Sbjct: 530 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 589 Query: 319 -PEKPLFSSASPQDSSPRLSTFPQHHHPGIP-GVAHSV------ISTRTPPPPSPLPFPT 370 P+KP +P + ST P P G A + + + P P +P Sbjct: 590 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 649 Query: 371 QAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQT 413 + PAP++ P P L P T + D +P T Sbjct: 650 TTLKEPAPTT----PKKPAPKELAPTTTKGPTSTTSDKPAPTT 688 Score = 36.6 bits (83), Expect = 0.044 Identities = 37/148 (25%), Positives = 61/148 (41%), Gaps = 18/148 (12%) Query: 267 PSSKRPKTISIDENMEPSPTGDFYPSPSSP-AAGSRTWHERDQDMSSPTTMKKPEKPLFS 325 P+ P+ ++ EP+PT P+P++P AA T E +PTT K+P + Sbjct: 506 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE-----PAPTTPKEP-----A 555 Query: 326 SASPQDSSPRLSTFPQHHHPGIP-GVAHSVISTRTPPPPSPLPFPTQAILPPAPSSYFSH 384 +P++ +P T P+ P P G A + + P P P L P + + Sbjct: 556 PTTPKEPAP---TTPKETAPTTPKGTAPTTLKEPAPTTPKK---PAPKELAPTTTKEPTS 609 Query: 385 PTIRYPPHLNPQDTLKNYVPSYDPSSPQ 412 T P P+ T P++P+ Sbjct: 610 TTCDKPAPTTPKGTAPTTPKEPAPTTPK 637 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 43.5 bits (101), Expect = 4e-04 Identities = 34/106 (32%), Positives = 48/106 (45%), Gaps = 15/106 (14%) Query: 264 SSPPSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSSPTTMKKPEKPL 323 S P+ PK + EP+PT P+P++P T E +S+PTT K+P Sbjct: 722 SDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSE----VSTPTTTKEPTT-- 775 Query: 324 FSSASPQDSSPRLSTFPQ----HHHPGIPGVAHSVISTRTPPPPSP 365 SP +S+P LS P + P PGV +T+TP P Sbjct: 776 -IHKSPDESTPELSAEPTPKALENSPKEPGVP----TTKTPAATKP 816 Score = 43.1 bits (100), Expect = 5e-04 Identities = 37/156 (23%), Positives = 60/156 (38%), Gaps = 20/156 (12%) Query: 267 PSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSSPTTMKKPEKPLFSS 326 P+ PK + EP+PT P+P++P ++PTT+K+P Sbjct: 656 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG------------TAPTTLKEPAPTTPKK 703 Query: 327 ASPQDSSPRLSTFPQHHHPGIPG-VAHSVISTRTPPPPSPL----PFPTQAILPPAPSSY 381 +P++ +P + P P + TP P+P P PT PP +S Sbjct: 704 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSE 763 Query: 382 FSHPTIRYPP---HLNPQDTLKNYVPSYDPSSPQTS 414 S PT P H +P ++ P + + S Sbjct: 764 VSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENS 799 Score = 40.4 bits (93), Expect = 0.003 Identities = 38/149 (25%), Positives = 57/149 (38%), Gaps = 19/149 (12%) Query: 267 PSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHER--DQDMSSPTTMKKPEKPLF 324 P+ PK + EPSPT P+P++ + T E S+PTT K+P Sbjct: 405 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 464 Query: 325 SSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPPSPL-PFPTQAILPPAPSSYFS 383 +P T P+ P P + P P +P P PT PAP+ Sbjct: 465 KEPAPTTPKEPAPTTPKKPAPTTP---------KEPAPTTPKEPAPT-TTKKPAPT---- 510 Query: 384 HPTIRYPPHLNPQDTLKNYVPSYDPSSPQ 412 T + P P++T P++P+ Sbjct: 511 --TPKEPAPTTPKETAPTTPKKLTPTTPE 537 Score = 38.1 bits (87), Expect = 0.015 Identities = 41/177 (23%), Positives = 66/177 (37%), Gaps = 18/177 (10%) Query: 240 PIGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTISIDENMEPSPTGDFYPSPSSPAAG 299 P P +P + S + + + P T EP+PT P+P++P Sbjct: 265 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK-----EPAPTTTKEPAPTTPKEP 319 Query: 300 SRTWHER---DQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVIS 356 + T + S+PTT K+P +P T P+ P P + Sbjct: 320 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP--KEPAPT 377 Query: 357 TRTPPPPSPL-PFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQ 412 T+ P P +P P PT A PAP+ T + P P++ P++P+ Sbjct: 378 TKEPAPTTPKEPAPT-APKKPAPT------TPKEPAPTTPKEPAPTTTKEPSPTTPK 427 Score = 37.7 bits (86), Expect = 0.020 Identities = 38/153 (24%), Positives = 57/153 (37%), Gaps = 16/153 (10%) Query: 267 PSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHER----DQDMSSPTTMKKPEKP 322 P+ PK + +P+PT P+P++P + T ++ + +PTT +KP Sbjct: 491 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT 550 Query: 323 LFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPPSPL----PFPTQAILPPAP 378 +P T P+ P P A + TP P+P P PT P P Sbjct: 551 TPEELAPTTPEEPTPTTPEEPAPTTPKAA----APNTPKEPAPTTPKEPAPT---TPKEP 603 Query: 379 SSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSP 411 + T P TLK P+ P P Sbjct: 604 APTTPKETAPTTPKGTAPTTLKEPAPT-TPKKP 635 Score = 37.4 bits (85), Expect = 0.026 Identities = 36/157 (22%), Positives = 64/157 (40%), Gaps = 20/157 (12%) Query: 267 PSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSSPTTMKK-----PEK 321 P+ PK + EP+PT P+P++P + T E +PTT K+ P+K Sbjct: 342 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE-----PAPTTPKEPAPTAPKK 396 Query: 322 PLFSS------ASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPPSPLPFPTQAILP 375 P ++ +P++ +P + P P P + +T++ P + P PT Sbjct: 397 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP----APTTTKSAPTTTKEPAPTTTKSA 452 Query: 376 PAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQ 412 P S T + P P++ P++P+ Sbjct: 453 PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 489 Score = 37.0 bits (84), Expect = 0.034 Identities = 39/163 (23%), Positives = 64/163 (39%), Gaps = 20/163 (12%) Query: 267 PSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDM----SSPTTMKK---- 318 P+ PK + + EP+PT P+P++P + T + ++PTT+K+ Sbjct: 571 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 630 Query: 319 -PEKPLFSSASPQDSSPRLSTFPQHHHPGIP-GVAHSV------ISTRTPPPPSPLPFPT 370 P+KP +P + ST P P G A + + + P P +P Sbjct: 631 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 690 Query: 371 QAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQT 413 + PAP++ P P L P T + D +P T Sbjct: 691 TTLKEPAPTT----PKKPAPKELAPTTTKGPTSTTSDKPAPTT 729 Score = 36.6 bits (83), Expect = 0.044 Identities = 37/148 (25%), Positives = 61/148 (41%), Gaps = 18/148 (12%) Query: 267 PSSKRPKTISIDENMEPSPTGDFYPSPSSP-AAGSRTWHERDQDMSSPTTMKKPEKPLFS 325 P+ P+ ++ EP+PT P+P++P AA T E +PTT K+P + Sbjct: 547 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE-----PAPTTPKEP-----A 596 Query: 326 SASPQDSSPRLSTFPQHHHPGIP-GVAHSVISTRTPPPPSPLPFPTQAILPPAPSSYFSH 384 +P++ +P T P+ P P G A + + P P P L P + + Sbjct: 597 PTTPKEPAP---TTPKETAPTTPKGTAPTTLKEPAPTTPKK---PAPKELAPTTTKEPTS 650 Query: 385 PTIRYPPHLNPQDTLKNYVPSYDPSSPQ 412 T P P+ T P++P+ Sbjct: 651 TTCDKPAPTTPKGTAPTTPKEPAPTTPK 678 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 43.5 bits (101), Expect = 4e-04 Identities = 34/106 (32%), Positives = 48/106 (45%), Gaps = 15/106 (14%) Query: 264 SSPPSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSSPTTMKKPEKPL 323 S P+ PK + EP+PT P+P++P T E +S+PTT K+P Sbjct: 774 SDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSE----VSTPTTTKEPTT-- 827 Query: 324 FSSASPQDSSPRLSTFPQ----HHHPGIPGVAHSVISTRTPPPPSP 365 SP +S+P LS P + P PGV +T+TP P Sbjct: 828 -IHKSPDESTPELSAEPTPKALENSPKEPGVP----TTKTPAATKP 868 Score = 43.1 bits (100), Expect = 5e-04 Identities = 37/156 (23%), Positives = 60/156 (38%), Gaps = 20/156 (12%) Query: 267 PSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSSPTTMKKPEKPLFSS 326 P+ PK + EP+PT P+P++P ++PTT+K+P Sbjct: 708 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG------------TAPTTLKEPAPTTPKK 755 Query: 327 ASPQDSSPRLSTFPQHHHPGIPG-VAHSVISTRTPPPPSPL----PFPTQAILPPAPSSY 381 +P++ +P + P P + TP P+P P PT PP +S Sbjct: 756 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSE 815 Query: 382 FSHPTIRYPP---HLNPQDTLKNYVPSYDPSSPQTS 414 S PT P H +P ++ P + + S Sbjct: 816 VSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENS 851 Score = 40.4 bits (93), Expect = 0.003 Identities = 38/149 (25%), Positives = 57/149 (38%), Gaps = 19/149 (12%) Query: 267 PSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHER--DQDMSSPTTMKKPEKPLF 324 P+ PK + EPSPT P+P++ + T E S+PTT K+P Sbjct: 457 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 516 Query: 325 SSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPPSPL-PFPTQAILPPAPSSYFS 383 +P T P+ P P + P P +P P PT PAP+ Sbjct: 517 KEPAPTTPKEPAPTTPKKPAPTTP---------KEPAPTTPKEPAPT-TTKKPAPT---- 562 Query: 384 HPTIRYPPHLNPQDTLKNYVPSYDPSSPQ 412 T + P P++T P++P+ Sbjct: 563 --TPKEPAPTTPKETAPTTPKKLTPTTPE 589 Score = 38.1 bits (87), Expect = 0.015 Identities = 41/177 (23%), Positives = 66/177 (37%), Gaps = 18/177 (10%) Query: 240 PIGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTISIDENMEPSPTGDFYPSPSSPAAG 299 P P +P + S + + + P T EP+PT P+P++P Sbjct: 317 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK-----EPAPTTTKEPAPTTPKEP 371 Query: 300 SRTWHER---DQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVIS 356 + T + S+PTT K+P +P T P+ P P + Sbjct: 372 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP--KEPAPT 429 Query: 357 TRTPPPPSPL-PFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQ 412 T+ P P +P P PT A PAP+ T + P P++ P++P+ Sbjct: 430 TKEPAPTTPKEPAPT-APKKPAPT------TPKEPAPTTPKEPAPTTTKEPSPTTPK 479 Score = 37.7 bits (86), Expect = 0.020 Identities = 38/153 (24%), Positives = 57/153 (37%), Gaps = 16/153 (10%) Query: 267 PSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHER----DQDMSSPTTMKKPEKP 322 P+ PK + +P+PT P+P++P + T ++ + +PTT +KP Sbjct: 543 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT 602 Query: 323 LFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPPSPL----PFPTQAILPPAP 378 +P T P+ P P A + TP P+P P PT P P Sbjct: 603 TPEELAPTTPEEPTPTTPEEPAPTTPKAA----APNTPKEPAPTTPKEPAPT---TPKEP 655 Query: 379 SSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSP 411 + T P TLK P+ P P Sbjct: 656 APTTPKETAPTTPKGTAPTTLKEPAPT-TPKKP 687 Score = 37.4 bits (85), Expect = 0.026 Identities = 36/157 (22%), Positives = 64/157 (40%), Gaps = 20/157 (12%) Query: 267 PSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSSPTTMKK-----PEK 321 P+ PK + EP+PT P+P++P + T E +PTT K+ P+K Sbjct: 394 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE-----PAPTTPKEPAPTAPKK 448 Query: 322 PLFSS------ASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPPSPLPFPTQAILP 375 P ++ +P++ +P + P P P + +T++ P + P PT Sbjct: 449 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP----APTTTKSAPTTTKEPAPTTTKSA 504 Query: 376 PAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQ 412 P S T + P P++ P++P+ Sbjct: 505 PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 541 Score = 37.0 bits (84), Expect = 0.034 Identities = 39/163 (23%), Positives = 64/163 (39%), Gaps = 20/163 (12%) Query: 267 PSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDM----SSPTTMKK---- 318 P+ PK + + EP+PT P+P++P + T + ++PTT+K+ Sbjct: 623 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 682 Query: 319 -PEKPLFSSASPQDSSPRLSTFPQHHHPGIP-GVAHSV------ISTRTPPPPSPLPFPT 370 P+KP +P + ST P P G A + + + P P +P Sbjct: 683 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 742 Query: 371 QAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQT 413 + PAP++ P P L P T + D +P T Sbjct: 743 TTLKEPAPTT----PKKPAPKELAPTTTKGPTSTTSDKPAPTT 781 Score = 36.6 bits (83), Expect = 0.044 Identities = 37/148 (25%), Positives = 61/148 (41%), Gaps = 18/148 (12%) Query: 267 PSSKRPKTISIDENMEPSPTGDFYPSPSSP-AAGSRTWHERDQDMSSPTTMKKPEKPLFS 325 P+ P+ ++ EP+PT P+P++P AA T E +PTT K+P + Sbjct: 599 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE-----PAPTTPKEP-----A 648 Query: 326 SASPQDSSPRLSTFPQHHHPGIP-GVAHSVISTRTPPPPSPLPFPTQAILPPAPSSYFSH 384 +P++ +P T P+ P P G A + + P P P L P + + Sbjct: 649 PTTPKEPAP---TTPKETAPTTPKGTAPTTLKEPAPTTPKK---PAPKELAPTTTKEPTS 702 Query: 385 PTIRYPPHLNPQDTLKNYVPSYDPSSPQ 412 T P P+ T P++P+ Sbjct: 703 TTCDKPAPTTPKGTAPTTPKEPAPTTPK 730 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 43.5 bits (101), Expect = 4e-04 Identities = 34/106 (32%), Positives = 48/106 (45%), Gaps = 15/106 (14%) Query: 264 SSPPSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSSPTTMKKPEKPL 323 S P+ PK + EP+PT P+P++P T E +S+PTT K+P Sbjct: 815 SDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSE----VSTPTTTKEPTT-- 868 Query: 324 FSSASPQDSSPRLSTFPQ----HHHPGIPGVAHSVISTRTPPPPSP 365 SP +S+P LS P + P PGV +T+TP P Sbjct: 869 -IHKSPDESTPELSAEPTPKALENSPKEPGVP----TTKTPAATKP 909 Score = 43.1 bits (100), Expect = 5e-04 Identities = 37/156 (23%), Positives = 60/156 (38%), Gaps = 20/156 (12%) Query: 267 PSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSSPTTMKKPEKPLFSS 326 P+ PK + EP+PT P+P++P ++PTT+K+P Sbjct: 749 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG------------TAPTTLKEPAPTTPKK 796 Query: 327 ASPQDSSPRLSTFPQHHHPGIPG-VAHSVISTRTPPPPSPL----PFPTQAILPPAPSSY 381 +P++ +P + P P + TP P+P P PT PP +S Sbjct: 797 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSE 856 Query: 382 FSHPTIRYPP---HLNPQDTLKNYVPSYDPSSPQTS 414 S PT P H +P ++ P + + S Sbjct: 857 VSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENS 892 Score = 40.4 bits (93), Expect = 0.003 Identities = 38/149 (25%), Positives = 57/149 (38%), Gaps = 19/149 (12%) Query: 267 PSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHER--DQDMSSPTTMKKPEKPLF 324 P+ PK + EPSPT P+P++ + T E S+PTT K+P Sbjct: 498 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 557 Query: 325 SSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPPSPL-PFPTQAILPPAPSSYFS 383 +P T P+ P P + P P +P P PT PAP+ Sbjct: 558 KEPAPTTPKEPAPTTPKKPAPTTP---------KEPAPTTPKEPAPT-TTKKPAPT---- 603 Query: 384 HPTIRYPPHLNPQDTLKNYVPSYDPSSPQ 412 T + P P++T P++P+ Sbjct: 604 --TPKEPAPTTPKETAPTTPKKLTPTTPE 630 Score = 38.1 bits (87), Expect = 0.015 Identities = 41/177 (23%), Positives = 66/177 (37%), Gaps = 18/177 (10%) Query: 240 PIGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTISIDENMEPSPTGDFYPSPSSPAAG 299 P P +P + S + + + P T EP+PT P+P++P Sbjct: 358 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK-----EPAPTTTKEPAPTTPKEP 412 Query: 300 SRTWHER---DQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVIS 356 + T + S+PTT K+P +P T P+ P P + Sbjct: 413 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP--KEPAPT 470 Query: 357 TRTPPPPSPL-PFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQ 412 T+ P P +P P PT A PAP+ T + P P++ P++P+ Sbjct: 471 TKEPAPTTPKEPAPT-APKKPAPT------TPKEPAPTTPKEPAPTTTKEPSPTTPK 520 Score = 37.7 bits (86), Expect = 0.020 Identities = 38/153 (24%), Positives = 57/153 (37%), Gaps = 16/153 (10%) Query: 267 PSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHER----DQDMSSPTTMKKPEKP 322 P+ PK + +P+PT P+P++P + T ++ + +PTT +KP Sbjct: 584 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT 643 Query: 323 LFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPPSPL----PFPTQAILPPAP 378 +P T P+ P P A + TP P+P P PT P P Sbjct: 644 TPEELAPTTPEEPTPTTPEEPAPTTPKAA----APNTPKEPAPTTPKEPAPT---TPKEP 696 Query: 379 SSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSP 411 + T P TLK P+ P P Sbjct: 697 APTTPKETAPTTPKGTAPTTLKEPAPT-TPKKP 728 Score = 37.4 bits (85), Expect = 0.026 Identities = 36/157 (22%), Positives = 64/157 (40%), Gaps = 20/157 (12%) Query: 267 PSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSSPTTMKK-----PEK 321 P+ PK + EP+PT P+P++P + T E +PTT K+ P+K Sbjct: 435 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE-----PAPTTPKEPAPTAPKK 489 Query: 322 PLFSS------ASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPPSPLPFPTQAILP 375 P ++ +P++ +P + P P P + +T++ P + P PT Sbjct: 490 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP----APTTTKSAPTTTKEPAPTTTKSA 545 Query: 376 PAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQ 412 P S T + P P++ P++P+ Sbjct: 546 PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 582 Score = 37.0 bits (84), Expect = 0.034 Identities = 39/163 (23%), Positives = 64/163 (39%), Gaps = 20/163 (12%) Query: 267 PSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDM----SSPTTMKK---- 318 P+ PK + + EP+PT P+P++P + T + ++PTT+K+ Sbjct: 664 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 723 Query: 319 -PEKPLFSSASPQDSSPRLSTFPQHHHPGIP-GVAHSV------ISTRTPPPPSPLPFPT 370 P+KP +P + ST P P G A + + + P P +P Sbjct: 724 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 783 Query: 371 QAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQT 413 + PAP++ P P L P T + D +P T Sbjct: 784 TTLKEPAPTT----PKKPAPKELAPTTTKGPTSTTSDKPAPTT 822 Score = 36.6 bits (83), Expect = 0.044 Identities = 37/148 (25%), Positives = 61/148 (41%), Gaps = 18/148 (12%) Query: 267 PSSKRPKTISIDENMEPSPTGDFYPSPSSP-AAGSRTWHERDQDMSSPTTMKKPEKPLFS 325 P+ P+ ++ EP+PT P+P++P AA T E +PTT K+P + Sbjct: 640 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE-----PAPTTPKEP-----A 689 Query: 326 SASPQDSSPRLSTFPQHHHPGIP-GVAHSVISTRTPPPPSPLPFPTQAILPPAPSSYFSH 384 +P++ +P T P+ P P G A + + P P P L P + + Sbjct: 690 PTTPKEPAP---TTPKETAPTTPKGTAPTTLKEPAPTTPKK---PAPKELAPTTTKEPTS 743 Query: 385 PTIRYPPHLNPQDTLKNYVPSYDPSSPQ 412 T P P+ T P++P+ Sbjct: 744 TTCDKPAPTTPKGTAPTTPKEPAPTTPK 771 >gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] Length = 1970 Score = 43.5 bits (101), Expect = 4e-04 Identities = 74/285 (25%), Positives = 97/285 (34%), Gaps = 30/285 (10%) Query: 142 PLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFLAYYVQEQDSGQSGSPSHN--D 199 P + G SP+ +P + P + S Y + S SPS++ Sbjct: 1567 PTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTS 1626 Query: 200 PAKNP--PGYLEDSFVKSGVFNVSELVRVSRTPITQGTGVNFPIGEIPSQPYYHDMNSGV 257 P+ +P P Y S S S +P + P P+ P Y + Sbjct: 1627 PSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP-SYSPTSPSYSPTSPSY 1685 Query: 258 NLQRSLSSPPSSKRPKTISIDENMEPS--PTGDFYPSPSSPAAGSRTWHERDQDMSSPTT 315 + SP S T PS PT Y SP+SP+ + SPT+ Sbjct: 1686 SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY-SPTSPS------YSPTSPSYSPTS 1738 Query: 316 MK-KPEKPLFSSASPQ--DSSPRLSTFPQHHHPGIPGVAHSVISTRTPP---PPSPLPFP 369 P P +S SP +SP S + P P T T P P SP P Sbjct: 1739 PSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNY------TPTSPNYSPTSPSYSP 1792 Query: 370 TQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQTS 414 T P SY S + RY P T PSY PSSP S Sbjct: 1793 TSPSYSPTSPSY-SPSSPRYTPQ---SPTYTPSSPSYSPSSPSYS 1833 Score = 41.6 bits (96), Expect = 0.001 Identities = 67/253 (26%), Positives = 92/253 (36%), Gaps = 24/253 (9%) Query: 183 YVQEQDSGQSGSPSHNDPA---KNPPGYLEDSFVKSGVFNVSELVRVSRTPITQGTGVNF 239 Y+ S S S PA ++P GY S S S +P + Sbjct: 1581 YIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTS 1640 Query: 240 PIGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTISIDENMEPS--PTGDFYPSPSSPA 297 P P+ P Y + + SP S T PS PT Y SP+SP+ Sbjct: 1641 P-SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY-SPTSPS 1698 Query: 298 AG--SRTWHERDQDMSSPTTMKKPEKPLFSSASPQDS--SPRLSTFPQHHHPGIPGVAHS 353 S ++ S + P P +S SP S SP S ++ P P + Sbjct: 1699 YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPT 1758 Query: 354 VIS-TRTPP---PPSPLPFPTQAILPPAPSSY------FSHPTIRYPPHLNPQDTLKNYV 403 S + T P P SP PT P SY +S + Y P +P+ T ++ Sbjct: 1759 SPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPS-SPRYTPQS-- 1815 Query: 404 PSYDPSSPQTSQS 416 P+Y PSSP S S Sbjct: 1816 PTYTPSSPSYSPS 1828 Score = 41.2 bits (95), Expect = 0.002 Identities = 51/182 (28%), Positives = 67/182 (36%), Gaps = 16/182 (8%) Query: 245 PSQPYYHDMNSGVNLQRSLSSPPSSKRPKTISIDENMEP-----SPTGDFYPSPSSPAAG 299 P+ P Y + G +S S P+S P + P SPT Y SP+SP+ Sbjct: 1595 PTSPAYEPRSPGGYTPQSPSYSPTS--PSYSPTSPSYSPTSPNYSPTSPSY-SPTSPSYS 1651 Query: 300 --SRTWHERDQDMSSPTTMKKPEKPLFSSASPQDS--SPRLSTFPQHHHPGIPGVAHSVI 355 S ++ S + P P +S SP S SP S + P P + + Sbjct: 1652 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP 1711 Query: 356 STRTPPPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQTSQ 415 S P SP PT P SY P N T NY P+ PS TS Sbjct: 1712 SYS---PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTS-PSYSPTSP 1767 Query: 416 SW 417 S+ Sbjct: 1768 SY 1769 Score = 38.5 bits (88), Expect = 0.012 Identities = 62/245 (25%), Positives = 82/245 (33%), Gaps = 34/245 (13%) Query: 190 GQSGSPSHNDP-AKNPPGYLEDSFVKSGVFNVSELVRVSRTPITQGTGVNFPIGEIPSQP 248 G GSP + P +P G + S+ +P + P G P P Sbjct: 1570 GSPGSPGPSSPYIPSPGGAMSPSY----------------SPTSPAYEPRSPGGYTPQSP 1613 Query: 249 YYHDMNSGVNLQRSLSSPPSSKRPKTISIDENMEPS--PTGDFYP------SPSSPAAG- 299 Y + + SP S T PS PT Y SP+SP+ Sbjct: 1614 SYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1673 Query: 300 -SRTWHERDQDMSSPTTMKKPEKPLFSSASPQDS--SPRLSTFPQHHHPGIPGVAHSVIS 356 S ++ S + P P +S SP S SP S + P P + + S Sbjct: 1674 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1733 Query: 357 -TRTPP---PPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQ 412 + T P P SP PT P SY P N T NY P+ PS Sbjct: 1734 YSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTS-PSYSP 1792 Query: 413 TSQSW 417 TS S+ Sbjct: 1793 TSPSY 1797 >gi|116284398 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 42.7 bits (99), Expect = 6e-04 Identities = 35/139 (25%), Positives = 50/139 (35%), Gaps = 15/139 (10%) Query: 264 SSPPSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSSPTTMKKPEKPL 323 SSP + P P PT +P A G + + SSP + + P P Sbjct: 196 SSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPT 255 Query: 324 FSSA---------SPQDSSPRLSTF------PQHHHPGIPGVAHSVISTRTPPPPSPLPF 368 S A P + P + PQ++ P +P S++ PPPP P Sbjct: 256 PSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSR 315 Query: 369 PTQAILPPAPSSYFSHPTI 387 P LPP+ S P + Sbjct: 316 PGPPPLPPSSSGNDETPRL 334 Score = 40.0 bits (92), Expect = 0.004 Identities = 44/145 (30%), Positives = 54/145 (37%), Gaps = 30/145 (20%) Query: 264 SSPPSSKRPKTISIDENMEPSPTG--DFYPSPSSPAAGSRTWHERDQDMSSPTTMKKPEK 321 SS P S RP + P+P+ D P P P G+R R+ P KP Sbjct: 242 SSSPFSNRPP-------LPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPV 294 Query: 322 PLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSV---------------ISTRTPPPPSPL 366 P S+ P SS P PG P + S +S+ TPP PSP Sbjct: 295 P--STPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSP- 351 Query: 367 PFPTQAILPPAPSSYFSHPTIRYPP 391 LPP PS P +R PP Sbjct: 352 --GRSGPLPPPPSER-PPPPVRDPP 373 Score = 37.4 bits (85), Expect = 0.026 Identities = 37/124 (29%), Positives = 49/124 (39%), Gaps = 15/124 (12%) Query: 266 PPSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSSPTTMKKP-EKPLF 324 PP RP +I + P P + P PS+P + + Q P +P PL Sbjct: 269 PPVGNRP-SIHREAVPPPPPQNNKPPVPSTPRPSASS-----QAPPPPPPPSRPGPPPLP 322 Query: 325 SSASPQDSSPRL--------STFPQHHHPGIPGVAHSVISTRTPPPPSPLPFPTQAILPP 376 S+S D +PRL S+ P PG G S R PPP P + + PP Sbjct: 323 PSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPP 382 Query: 377 APSS 380 P S Sbjct: 383 PPVS 386 >gi|38373695 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 42.7 bits (99), Expect = 6e-04 Identities = 35/139 (25%), Positives = 50/139 (35%), Gaps = 15/139 (10%) Query: 264 SSPPSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSSPTTMKKPEKPL 323 SSP + P P PT +P A G + + SSP + + P P Sbjct: 196 SSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPT 255 Query: 324 FSSA---------SPQDSSPRLSTF------PQHHHPGIPGVAHSVISTRTPPPPSPLPF 368 S A P + P + PQ++ P +P S++ PPPP P Sbjct: 256 PSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSR 315 Query: 369 PTQAILPPAPSSYFSHPTI 387 P LPP+ S P + Sbjct: 316 PGPPPLPPSSSGNDETPRL 334 Score = 40.0 bits (92), Expect = 0.004 Identities = 44/145 (30%), Positives = 54/145 (37%), Gaps = 30/145 (20%) Query: 264 SSPPSSKRPKTISIDENMEPSPTG--DFYPSPSSPAAGSRTWHERDQDMSSPTTMKKPEK 321 SS P S RP + P+P+ D P P P G+R R+ P KP Sbjct: 242 SSSPFSNRPP-------LPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPV 294 Query: 322 PLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSV---------------ISTRTPPPPSPL 366 P S+ P SS P PG P + S +S+ TPP PSP Sbjct: 295 P--STPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSP- 351 Query: 367 PFPTQAILPPAPSSYFSHPTIRYPP 391 LPP PS P +R PP Sbjct: 352 --GRSGPLPPPPSER-PPPPVRDPP 373 Score = 37.4 bits (85), Expect = 0.026 Identities = 37/124 (29%), Positives = 49/124 (39%), Gaps = 15/124 (12%) Query: 266 PPSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSSPTTMKKP-EKPLF 324 PP RP +I + P P + P PS+P + + Q P +P PL Sbjct: 269 PPVGNRP-SIHREAVPPPPPQNNKPPVPSTPRPSASS-----QAPPPPPPPSRPGPPPLP 322 Query: 325 SSASPQDSSPRL--------STFPQHHHPGIPGVAHSVISTRTPPPPSPLPFPTQAILPP 376 S+S D +PRL S+ P PG G S R PPP P + + PP Sbjct: 323 PSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPP 382 Query: 377 APSS 380 P S Sbjct: 383 PPVS 386 >gi|19923345 RNA binding motif protein 12 [Homo sapiens] Length = 932 Score = 42.7 bits (99), Expect = 6e-04 Identities = 44/162 (27%), Positives = 64/162 (39%), Gaps = 23/162 (14%) Query: 258 NLQRSLSSPPSSKRPKTISIDENMEPSPTGDFY-PSPSSPAAGSRTWHERDQDMSSPTTM 316 N RS PPSS +++ P+ +F PSPS A + HE ++++ + +T Sbjct: 101 NASRS-GPPPSSGMSSRVNL-----PTTVSNFNNPSPSVVTATTSV-HESNKNIQTFSTA 153 Query: 317 KKPE----------KPLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPPSPL 366 P FSS P +SP ++T P P IP + PP P P Sbjct: 154 SVGTAPPNMGASFGSPTFSSTVPSTASP-MNTVPPPPIPPIPAMPSLPPMPSIPPIPVPP 212 Query: 367 PFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDP 408 P PT +PP P P + P + P + P P Sbjct: 213 PVPTLPPVPPVPPI----PPVPSVPPMTPLPPMSGMPPLNPP 250 >gi|23510462 RNA binding motif protein 12 [Homo sapiens] Length = 932 Score = 42.7 bits (99), Expect = 6e-04 Identities = 44/162 (27%), Positives = 64/162 (39%), Gaps = 23/162 (14%) Query: 258 NLQRSLSSPPSSKRPKTISIDENMEPSPTGDFY-PSPSSPAAGSRTWHERDQDMSSPTTM 316 N RS PPSS +++ P+ +F PSPS A + HE ++++ + +T Sbjct: 101 NASRS-GPPPSSGMSSRVNL-----PTTVSNFNNPSPSVVTATTSV-HESNKNIQTFSTA 153 Query: 317 KKPE----------KPLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPPSPL 366 P FSS P +SP ++T P P IP + PP P P Sbjct: 154 SVGTAPPNMGASFGSPTFSSTVPSTASP-MNTVPPPPIPPIPAMPSLPPMPSIPPIPVPP 212 Query: 367 PFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDP 408 P PT +PP P P + P + P + P P Sbjct: 213 PVPTLPPVPPVPPI----PPVPSVPPMTPLPPMSGMPPLNPP 250 >gi|46852390 coiled-coil domain containing 6 [Homo sapiens] Length = 474 Score = 42.7 bits (99), Expect = 6e-04 Identities = 41/155 (26%), Positives = 64/155 (41%), Gaps = 24/155 (15%) Query: 243 EIPSQPYYHDMNSGVNLQRSLSSP------PSSKRPKTISIDENMEPSPTGDFYPSPSSP 296 E+ + Y+++M++ R++SSP PSS RP + + S T F P S Sbjct: 330 EMDDERYFNEMSAQGLRPRTVSSPIPYTPSPSSSRPISPGLSY---ASHTVGFTPPTSLT 386 Query: 297 AAGSRTWHERDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFP-QHHHPGIPGVAHSVI 355 AG ++ + T +P SPR S P + P P ++ Sbjct: 387 RAGMSYYNSPGLHVQHMGTSHGITRP----------SPRRSNSPDKFKRPTPPPSPNTQT 436 Query: 356 STRTPPPPSPLPF----PTQAILPPAPSSYFSHPT 386 + PPPP P P P+ A P PS + +HP+ Sbjct: 437 PVQPPPPPPPPPMQPTVPSAATSQPTPSQHSAHPS 471 >gi|11386183 WAS protein family, member 2 [Homo sapiens] Length = 498 Score = 42.4 bits (98), Expect = 8e-04 Identities = 48/166 (28%), Positives = 61/166 (36%), Gaps = 15/166 (9%) Query: 258 NLQRSLSSPP----SSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSSP 313 N+ S PP S+ P ++N+ P P YP + GS + + SP Sbjct: 240 NVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQ--RGSGLAGPKRSSVVSP 297 Query: 314 TTMKKPEKPLFSSASPQD--SSPRLSTFPQHHHPGIPGVAHSVI--STRTPPPPSPLPFP 369 + P PL S P+ + P P GIP V S TPPPPSP FP Sbjct: 298 SH-PPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFP 356 Query: 370 TQ----AILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSP 411 A PP P +PT+ PP P P P P Sbjct: 357 PHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGP 402 Score = 33.5 bits (75), Expect = 0.37 Identities = 53/226 (23%), Positives = 76/226 (33%), Gaps = 50/226 (22%) Query: 186 EQDSGQSGSPSHNDPAKNPP----GYLEDSFVKSGVFNV--SELVRVSRTPITQGTGVNF 239 + DS S SPS ++ PP Y D+ SG+ S +V S P Sbjct: 251 QSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAP------ 304 Query: 240 PIGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTISIDENMEPSPTGDFYPSPSSPAAG 299 P+G P + + PP+ P I P P G + SP +P Sbjct: 305 PLGSPPGP------------KPGFAPPPAPPPPPPPMIGIPPPPPPVG--FGSPGTPPP- 349 Query: 300 SRTWHERDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRT 359 P+ P P F++ P P +P +P S + Sbjct: 350 -------------PSPPSFPPHPDFAAPPPPPPPPAAD------YPTLPPPPLSQPTGGA 390 Query: 360 PPPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPS 405 PPPP P P P PP P + PP L+ K+ +P+ Sbjct: 391 PPPPPPPPPPG----PPPPPFTGADGQPAIPPPLSDTTKPKSSLPA 432 >gi|151301154 mucin 6, gastric [Homo sapiens] Length = 2439 Score = 42.4 bits (98), Expect = 8e-04 Identities = 44/149 (29%), Positives = 56/149 (37%), Gaps = 30/149 (20%) Query: 285 PTGDFYPSPSSPAAGSRTWHERDQDMSSPTTMKKPEKPL-FSSASPQDSSPRLSTFPQHH 343 PTG P + A GS +PTT + P FS+A S P ++ H Sbjct: 1873 PTGTIPPPTTIKATGST----HTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTS--STH 1926 Query: 344 HPGIPGVA-------HSVISTRTP------PPPSPLPFPTQAILPPAPSSYFS------- 383 HP + + H+ TRTP S LP P PP SS FS Sbjct: 1927 HPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTA 1986 Query: 384 ---HPTIRYPPHLNPQDTLKNYVPSYDPS 409 T YP +PQ TL +VP + S Sbjct: 1987 TSFQTTTTYPTPSHPQTTLPTHVPPFSTS 2015 Score = 40.4 bits (93), Expect = 0.003 Identities = 41/172 (23%), Positives = 66/172 (38%), Gaps = 16/172 (9%) Query: 248 PYYHDMNSGVNLQRSLSSPPSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERD 307 P H + + + Q + S+ S TI ++ + + P + +G+ H Sbjct: 1457 PSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSF 1516 Query: 308 QDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPPSPLP 367 +PT++ S+ ++ P P VAH+ +T + PPP P Sbjct: 1517 STNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTP-VAHTNSATSSRPPP---P 1572 Query: 368 FPTQAILPPAPSSYFSHP----------TIRYPPHLNPQDTLKNYVPSYDPS 409 F T + PP SS FS T YP +PQ TL +VP + S Sbjct: 1573 FTTHS--PPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTS 1622 Score = 35.8 bits (81), Expect = 0.075 Identities = 55/244 (22%), Positives = 84/244 (34%), Gaps = 34/244 (13%) Query: 167 HHITVSVKELDLFLAYYVQEQDSGQSGSPSHNDPAKNPPGYLEDSFVKSGVFNVSELVRV 226 +H S + L A + + SG P A P SG+ + L Sbjct: 1243 NHTPASPTQTPLLPATLTSSKPTASSGEPPRPTTAVTPQA-------TSGLPPTATLRST 1295 Query: 227 SRTP-ITQGTGVNFPIGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTISIDENMEPSP 285 + P +TQ T S S +L +P +S T+ N E Sbjct: 1296 ATKPTVTQAT--TRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPG 1353 Query: 286 TGDFYPSPSSPAAGSRTWHERDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHP 345 T + P S T PTT +P +P +A+ + + T ++ P Sbjct: 1354 TTATQTTGPRPTPASTT---------GPTT-PQPGQPTRPTAT---ETTQTRTTTEYTTP 1400 Query: 346 GIPGVAHSVISTRTPPPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPS 405 P HS PP + P P+ P ++ F H T YP +P+ TL +VP Sbjct: 1401 QTPHTTHS-------PPTAGSPVPSTG---PVTATSF-HATTTYPTPSHPETTLPTHVPP 1449 Query: 406 YDPS 409 + S Sbjct: 1450 FSTS 1453 Score = 33.1 bits (74), Expect = 0.48 Identities = 37/139 (26%), Positives = 54/139 (38%), Gaps = 14/139 (10%) Query: 280 NMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSSPTTMKKPEKPLFSSASPQ-DSSPRLST 338 N+ P+PT P + +G+ + S+ T S+ P+ S+ S Sbjct: 1713 NITPNPTSTGTPPMTVTTSGTS---QSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSI 1769 Query: 339 FPQHHHPGI-PGVAH--SVISTRTPPP-----PSPLPFPTQAILPPAPSSYFSHPTIRYP 390 P H G VAH S S+R P P P P + P +S+ T YP Sbjct: 1770 TPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSF--QTTTTYP 1827 Query: 391 PHLNPQDTLKNYVPSYDPS 409 +P TL +VPS+ S Sbjct: 1828 TPSHPHTTLPTHVPSFSTS 1846 Score = 29.3 bits (64), Expect = 7.0 Identities = 36/126 (28%), Positives = 50/126 (39%), Gaps = 14/126 (11%) Query: 266 PPSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSSP-TTMKKPEKPLF 324 P + P T+S + P T P+PSS A S S+P TT P F Sbjct: 2213 PHTISSPFTLSA---LLPISTVTVSPTPSSHLASSTIAFP-----STPRTTASTHTAPAF 2264 Query: 325 SSASPQDSSPRLST-FPQHHH----PGIPGVAHSVISTRTPPPPSPLPFPTQAILPPAPS 379 SS S S L+T P G+ G+ S ++ T P P PT L + + Sbjct: 2265 SSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLT 2324 Query: 380 SYFSHP 385 ++ S P Sbjct: 2325 AHGSTP 2330 >gi|40788007 FYN binding protein (FYB-120/130) isoform 2 [Homo sapiens] Length = 783 Score = 42.4 bits (98), Expect = 8e-04 Identities = 40/145 (27%), Positives = 60/145 (41%), Gaps = 18/145 (12%) Query: 275 ISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQ---DMSSPTTMKKPEKPLFSSASPQD 331 I+ +E +P F +PS G +++ D +S T +KP PLF+ P Sbjct: 299 INQEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPP 358 Query: 332 SSPR-----LSTFPQHHHPGIPGVAHSVISTRTPPPPSPLPFPTQAILPPAPSSYFSHPT 386 R L+ F + + ST + PPP P +Q PP P+S+ S P Sbjct: 359 KPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQ---PPLPASHPSQPP 415 Query: 387 IRYPPHLNPQDTLKNYVPSYDPSSP 411 + P L P +N P +D SP Sbjct: 416 V---PSLPP----RNIKPPFDLKSP 433 >gi|42476118 FYN binding protein (FYB-120/130) isoform 1 [Homo sapiens] Length = 829 Score = 42.4 bits (98), Expect = 8e-04 Identities = 40/145 (27%), Positives = 60/145 (41%), Gaps = 18/145 (12%) Query: 275 ISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQ---DMSSPTTMKKPEKPLFSSASPQD 331 I+ +E +P F +PS G +++ D +S T +KP PLF+ P Sbjct: 299 INQEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPP 358 Query: 332 SSPR-----LSTFPQHHHPGIPGVAHSVISTRTPPPPSPLPFPTQAILPPAPSSYFSHPT 386 R L+ F + + ST + PPP P +Q PP P+S+ S P Sbjct: 359 KPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQ---PPLPASHPSQPP 415 Query: 387 IRYPPHLNPQDTLKNYVPSYDPSSP 411 + P L P +N P +D SP Sbjct: 416 V---PSLPP----RNIKPPFDLKSP 433 >gi|150170729 microtubule associated serine/threonine kinase 3 [Homo sapiens] Length = 1309 Score = 42.4 bits (98), Expect = 8e-04 Identities = 36/128 (28%), Positives = 52/128 (40%), Gaps = 18/128 (14%) Query: 268 SSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSSPTTMKKPEKPLFSSA 327 SS ++S E++ SPT PSP++P D+ + TT P SA Sbjct: 1093 SSGLHHSLSSSESLPGSPTHSLSPSPTTPCRSPA------PDVPADTTASPP------SA 1140 Query: 328 SPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPPSPLPFPTQAILPPAPSSYFSHPTI 387 SP SSP H P H + + PP P + + +PP+P + P I Sbjct: 1141 SPSSSSPASPAAAGHTR---PSSLHGLAAKLGPPRPKTGRRKSTSSIPPSP---LACPPI 1194 Query: 388 RYPPHLNP 395 PP +P Sbjct: 1195 SAPPPRSP 1202 >gi|28558973 mediator complex subunit 14 [Homo sapiens] Length = 1454 Score = 41.6 bits (96), Expect = 0.001 Identities = 58/260 (22%), Positives = 86/260 (33%), Gaps = 54/260 (20%) Query: 176 LDLFLAYYVQEQDSGQSGSPSHNDPAKNPPGYLEDSFVKSGVFNVSELVRVSRTPITQGT 235 L FL +V + S + +D NPP + + S + + + P GT Sbjct: 959 LKTFLNMFVDSNQDARRRSVNEDD---NPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGT 1015 Query: 236 GVNFPIGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTISIDENMEPSPTGDFYPSPS- 294 +P+ P+ Y+ +N ++ + S P + + PSP F P+P Sbjct: 1016 SGAYPLTSPPTS-YHSTVNQSPSMMHTQS--PGNLHAASSPSGALRAPSPAS-FVPTPPP 1071 Query: 295 -------SPAAGSRTWHERDQDMSSPTTMKKPE--------KPLFSSASPQDSSPRLSTF 339 P A + H D SSP TM P P S SP P +S Sbjct: 1072 SSHGISIGPGASFASPHGT-LDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPA 1130 Query: 340 PQHHHPGIPGVAHS--------VISTRTPPPPSP----------------------LPFP 369 H +P +HS + T PPP LP P Sbjct: 1131 NPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSP 1190 Query: 370 TQAILPPAPSSYFSHPTIRY 389 T ++P SY P R+ Sbjct: 1191 TPGLVPGLAGSYLCSPLERF 1210 >gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens] Length = 753 Score = 41.6 bits (96), Expect = 0.001 Identities = 44/158 (27%), Positives = 61/158 (38%), Gaps = 29/158 (18%) Query: 264 SSPPS-SKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMS-------SPTT 315 +SPPS S I + P+ T P P SPA + E D+ S + Sbjct: 241 TSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSP 300 Query: 316 MKKPEKPLFSSASPQD-------------SSPRLSTFPQHHHPGIPGVAHSVISTRTPPP 362 K KP+ S+ PQ ++ LST P ++ P S + + P Sbjct: 301 AKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPA 360 Query: 363 PS-----PLPFPTQAILPPAPSSYFSHPTIRYPPHLNP 395 PS P P+ QA+ PPAPS T PP + P Sbjct: 361 PSHNSGTPAPY-AQAVAPPAPSG--PSTTQPRPPSVQP 395 Score = 34.3 bits (77), Expect = 0.22 Identities = 43/171 (25%), Positives = 67/171 (39%), Gaps = 19/171 (11%) Query: 201 AKNPPGYLEDSFVKSGVFNVSELVRVSRTPITQGTGVNFPIGEIPS----QPYYHDMNSG 256 A +PP + S ++ +FN S S TP + T + PI P+ + D G Sbjct: 240 ATSPPSH---SHMEDEIFNQS-----SSTPTS--TTSSSPIPPSPANCTTENSEDDKKRG 289 Query: 257 VNLQRSLSSPPSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSSPTTM 316 + +S P+ K + +++ + YPS PAA + + + + +P Sbjct: 290 RSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAA- 348 Query: 317 KKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPPSPLP 367 P L ASP S S P + + A S ST P PPS P Sbjct: 349 --PPSALGPKASPAPS--HNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQP 395 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 41.2 bits (95), Expect = 0.002 Identities = 61/229 (26%), Positives = 89/229 (38%), Gaps = 30/229 (13%) Query: 194 SPSHNDPAKNPPGYLEDSFVKSGVFNV-SELVRVSRTPITQGTGVNFPIGEIPSQPYYHD 252 SP P +P LE+S + + S + +P + + ++ P E P P + Sbjct: 501 SPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEE 560 Query: 253 MNSGVNLQRSLSSPPSSKRPKTISIDENMEPSPTGDFYPSPSSPAA-GSRTWHERDQDMS 311 + + + S SPP + P M P P SP SP SR + ++ Sbjct: 561 LPTSPPPEASRLSPPPEESP--------MSPPPE----ESPMSPPPEASRLFPPFEE--- 605 Query: 312 SPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPP----SPLP 367 SP + E PL SP + RLS P P P S +S PPP SPLP Sbjct: 606 SPLSPPPEESPL----SPPPEASRLSP-PPEDSPMSPPPEESPMS---PPPEVSRLSPLP 657 Query: 368 FPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQTSQS 416 ++ + PP S S P P P+ + + P P+SP S Sbjct: 658 VVSR-LSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDS 705 Score = 38.5 bits (88), Expect = 0.012 Identities = 56/253 (22%), Positives = 85/253 (33%), Gaps = 46/253 (18%) Query: 188 DSGQSGSPSHNDPAKNPPGYLEDSFVKSGVFNVSELVRVSRTPITQGTGVNFPIGEIPSQ 247 + + P + PA PP EDS + P+ + P+ +P + Sbjct: 694 EDSPTSPPPEDSPASPPP---EDSLMS--------------LPLEES-----PLLPLPEE 731 Query: 248 PYYHDMNSGVNLQRSLSSPPSSKRPKTISI-----DENMEPSPTGDFY------PSPSSP 296 P + G +L P S RP+ + + ++ P P P S Sbjct: 732 PQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQ 791 Query: 297 AAGSRTWHERDQDMSSPTTMKK-----PEKPLFSSA------SPQDSSPRLSTFPQHHH- 344 A G + ++ SP T + PE+P S SPQ P LS P+ H Sbjct: 792 AEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHL 851 Query: 345 -PGIPGVAHSVISTRTPPPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYV 403 P + S + P P P P + L P P P + P P + + + Sbjct: 852 SPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPL 911 Query: 404 PSYDPSSPQTSQS 416 P P SP S Sbjct: 912 PEELPLSPSGEPS 924 Score = 37.7 bits (86), Expect = 0.020 Identities = 49/211 (23%), Positives = 76/211 (36%), Gaps = 23/211 (10%) Query: 229 TPITQGTGVNFPIGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKT-------------- 274 +P + + ++ P E+P+ P ++ L+ S SPP + P + Sbjct: 459 SPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEES 518 Query: 275 -ISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSSPTTMKKPEKPLFSSASPQDSS 333 +S E PSP + SP A+ E P + P S SP Sbjct: 519 PLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEE 578 Query: 334 PRLSTFPQHHHPGIPGVAHSVI-----STRTPPP-PSPLPFPTQA--ILPPAPSSYFSHP 385 +S P+ P A + S +PPP SPL P +A + PP S S P Sbjct: 579 SPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPP 638 Query: 386 TIRYPPHLNPQDTLKNYVPSYDPSSPQTSQS 416 P P+ + + +P SP +S Sbjct: 639 PEESPMSPPPEVSRLSPLPVVSRLSPPPEES 669 Score = 36.6 bits (83), Expect = 0.044 Identities = 55/246 (22%), Positives = 84/246 (34%), Gaps = 46/246 (18%) Query: 154 SPHCTNPALCVQPHHITVSVKELDLFLAYYVQEQDSGQSGSPSHNDPAKNPPGYL---ED 210 SP P L QP + +S + + L+ +E SH P P E+ Sbjct: 789 SPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEE 848 Query: 211 SFVKSGVFNVSELVRVSRTPITQG---TGVNFPIGEIPSQPYYHDMNSGVNLQRSLSSPP 267 S + + R + P G P+ P +P + L PP Sbjct: 849 SHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEP-GEPP 907 Query: 268 SSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSSPTTMKKPEKPLFSSA 327 S P+ + + + EPS + P P + P P+ ++A Sbjct: 908 LSPLPEELPLSPSGEPSLSPQLMP---------------------PDPLPPPLSPIITAA 946 Query: 328 SPQDSSPRLSTFPQHHHP-GIPG-------VAHSVISTRTPPPP-----SPLPFPTQAIL 374 +P P LS + +P G G +A ++ T PPP P P P IL Sbjct: 947 AP----PALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPM-IL 1001 Query: 375 PPAPSS 380 PP+P S Sbjct: 1002 PPSPGS 1007 Score = 36.2 bits (82), Expect = 0.057 Identities = 46/180 (25%), Positives = 69/180 (38%), Gaps = 31/180 (17%) Query: 244 IPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTISIDENMEPSPTGDFYPSPS-----SPAA 298 +P P + G + LS PP + K + + + E + Y P+ SP++ Sbjct: 2257 VPESP---GVGGGKASEPLLSPPPFGESRKALEVKKE-ELGASSPSYGPPNLGFVDSPSS 2312 Query: 299 GSRTWHERDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQH------------HHPG 346 G+ H ++ +P K P P S PQ SP L PQ HP Sbjct: 2313 GT---HLGGLELKTPDVFKAPLTPRASQVEPQ--SPGLGLRPQEPPPAQALAPSPPSHPD 2367 Query: 347 I--PGVAHSVISTRTPPPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVP 404 I PG +++ + P P P P P ++ P S S P R P +PQ + P Sbjct: 2368 IFRPG-SYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVP--ASPQSQSSSQSP 2424 Score = 29.3 bits (64), Expect = 7.0 Identities = 33/130 (25%), Positives = 43/130 (33%), Gaps = 9/130 (6%) Query: 259 LQRSLSSPPSSKRPKTISIDENMEP----SPTGDFYP---SPSSPAAGSRTWHERDQDMS 311 L+ +S PP + + + P SP G P P P H S Sbjct: 978 LETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNS 1037 Query: 312 SPTTMKKPEKPLF--SSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPPSPLPFP 369 P+ P PL S SP +S + H V+ P SPLP P Sbjct: 1038 PPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSP 1097 Query: 370 TQAILPPAPS 379 + PAPS Sbjct: 1098 MGDLSCPAPS 1107 >gi|116875765 tight junction protein 1 isoform b [Homo sapiens] Length = 1668 Score = 40.8 bits (94), Expect = 0.002 Identities = 38/126 (30%), Positives = 52/126 (41%), Gaps = 10/126 (7%) Query: 257 VNLQRSLSS----PPSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSS 312 ++ Q SL S PPS +P T N E + FYP S P E+ Q + Sbjct: 1383 LDFQNSLVSKPDPPPSQNKPATFR-PPNREDTAQAAFYPQKSFPDKAPVNGTEQTQKTVT 1441 Query: 313 PTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPG-VAHSV-ISTRTPPPPSPLPFPT 370 P + KP SSA P + R P+ +H +P AH +S++TP P L Sbjct: 1442 PAYNRFTPKPYTSSARPFE---RKFESPKFNHNLLPSETAHKPDLSSKTPTSPKTLVKSH 1498 Query: 371 QAILPP 376 PP Sbjct: 1499 SLAQPP 1504 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.132 0.409 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,605,888 Number of Sequences: 37866 Number of extensions: 1233767 Number of successful extensions: 10629 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 107 Number of HSP's successfully gapped in prelim test: 645 Number of HSP's that attempted gapping in prelim test: 7792 Number of HSP's gapped (non-prelim): 2436 length of query: 420 length of database: 18,247,518 effective HSP length: 105 effective length of query: 315 effective length of database: 14,271,588 effective search space: 4495550220 effective search space used: 4495550220 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.