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Search of human proteins with 13775208
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13775208 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 31 [Homo sapiens]
(315 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13775208 solute carrier family 25 (mitochondrial carrier; ade... 632 0.0
gi|55749577 solute carrier family 25 (mitochondrial carrier; ade... 437 e-123
gi|156071462 solute carrier family 25, member A6 [Homo sapiens] 434 e-122
gi|156071459 solute carrier family 25, member 5 [Homo sapiens] 428 e-120
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 132 4e-31
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 132 4e-31
gi|27544933 solute carrier family 25, member 16 [Homo sapiens] 125 6e-29
gi|21361103 solute carrier family 25, member 12 [Homo sapiens] 118 8e-27
gi|60460887 solute carrier family 25, member 42 [Homo sapiens] 117 1e-26
gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s... 117 2e-26
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo... 117 2e-26
gi|48476342 solute carrier family 25, member 23 [Homo sapiens] 116 2e-26
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 116 3e-26
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 116 3e-26
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 116 3e-26
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 116 3e-26
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ... 116 3e-26
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ... 116 3e-26
gi|149274607 solute carrier family 25, member 41 [Homo sapiens] 110 2e-24
gi|13375983 mitochondrial glutamate carrier 1 [Homo sapiens] 109 3e-24
gi|21687151 mitochondrial solute carrier protein [Homo sapiens] 102 4e-22
gi|13899342 solute carrier [Homo sapiens] 102 6e-22
gi|21314739 solute carrier family 25, member 32 [Homo sapiens] 97 1e-20
gi|13449279 solute carrier family 25 (mitochondrial oxodicarboxy... 96 4e-20
gi|108860679 solute carrier family 25, member 27 [Homo sapiens] 95 7e-20
gi|58197562 solute carrier family 25, member 30 [Homo sapiens] 94 1e-19
gi|186928856 solute carrier family 25, member 19 [Homo sapiens] 94 2e-19
gi|186928860 solute carrier family 25, member 19 [Homo sapiens] 94 2e-19
gi|186928858 solute carrier family 25, member 19 [Homo sapiens] 94 2e-19
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 93 3e-19
>gi|13775208 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 31 [Homo
sapiens]
Length = 315
Score = 632 bits (1629), Expect = 0.0
Identities = 315/315 (100%), Positives = 315/315 (100%)
Query: 1 MHREPAKKKAEKRLFDASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPE 60
MHREPAKKKAEKRLFDASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPE
Sbjct: 1 MHREPAKKKAEKRLFDASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPE 60
Query: 61 ARYKGMVDCLVRIPREQGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQ 120
ARYKGMVDCLVRIPREQGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQ
Sbjct: 61 ARYKGMVDCLVRIPREQGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQ 120
Query: 121 FWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSD 180
FWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSD
Sbjct: 121 FWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSD 180
Query: 181 GIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKKTPFLVSFFIAQVVTTCSGILS 240
GIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKKTPFLVSFFIAQVVTTCSGILS
Sbjct: 181 GIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKKTPFLVSFFIAQVVTTCSGILS 240
Query: 241 YPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGGALVLVL 300
YPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGGALVLVL
Sbjct: 241 YPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGGALVLVL 300
Query: 301 YDKIKEFFHIDIGGR 315
YDKIKEFFHIDIGGR
Sbjct: 301 YDKIKEFFHIDIGGR 315
>gi|55749577 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 4 [Homo
sapiens]
Length = 298
Score = 437 bits (1123), Expect = e-123
Identities = 216/293 (73%), Positives = 247/293 (84%), Gaps = 2/293 (0%)
Query: 17 ASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPRE 76
A SF KD LAGGVAAAVSKTAVAPIERVKLLLQVQ +SKQIS E +YKG++DC+VRIP+E
Sbjct: 5 AWSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKE 64
Query: 77 QGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAG 136
QGF SFWRGNLANVIRYFPTQALNFAFKDKYKQLF+ GV++ KQFWR+F NLASGGAAG
Sbjct: 65 QGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAG 124
Query: 137 ATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGI 196
ATSLC VYPLDFARTRL D+GKG +R+F GLGDCI+KI KSDG+ GLYQGF VSVQGI
Sbjct: 125 ATSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGI 184
Query: 197 IVYRASYFGAYDTVKGLLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGE 256
I+YRA+YFG YDT KG+LP PK VS+ IAQ VT +G++SYPFDTVRRRMMMQSG
Sbjct: 185 IIYRAAYFGVYDTAKGMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGR 244
Query: 257 --AKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGGALVLVLYDKIKEF 307
A Y GT+DC+ KI + EG +FF+GA+SNVLRG GGA VLVLYD+IK++
Sbjct: 245 KGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFVLVLYDEIKKY 297
>gi|156071462 solute carrier family 25, member A6 [Homo sapiens]
Length = 298
Score = 434 bits (1117), Expect = e-122
Identities = 211/292 (72%), Positives = 247/292 (84%), Gaps = 2/292 (0%)
Query: 17 ASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPRE 76
A SF KD LAGG+AAA+SKTAVAPIERVKLLLQVQ +SKQI+ + +YKG+VDC+VRIP+E
Sbjct: 5 AISFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKE 64
Query: 77 QGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAG 136
QG SFWRGNLANVIRYFPTQALNFAFKDKYKQ+F+ GV+K QFWR+F NLASGGAAG
Sbjct: 65 QGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGAAG 124
Query: 137 ATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGI 196
ATSLC VYPLDFARTRL D+GK ER+F+GLGDC++KI KSDGI GLYQGF VSVQGI
Sbjct: 125 ATSLCFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQGI 184
Query: 197 IVYRASYFGAYDTVKGLLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGE 256
I+YRA+YFG YDT KG+LP PK T +VS+ IAQ VT +G++SYPFDTVRRRMMMQSG
Sbjct: 185 IIYRAAYFGVYDTAKGMLPDPKNTHIVVSWMIAQTVTAVAGVVSYPFDTVRRRMMMQSGR 244
Query: 257 --AKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGGALVLVLYDKIKE 306
A Y GT+DC+ KI++ EG +FF+GA+SNVLRG GGA VLVLYD++K+
Sbjct: 245 KGADIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLRGMGGAFVLVLYDELKK 296
>gi|156071459 solute carrier family 25, member 5 [Homo sapiens]
Length = 298
Score = 428 bits (1101), Expect = e-120
Identities = 210/293 (71%), Positives = 244/293 (83%), Gaps = 2/293 (0%)
Query: 17 ASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPRE 76
A SF KD LAGGVAAA+SKTAVAPIERVKLLLQVQ +SKQI+ + +YKG++DC+VRIP+E
Sbjct: 5 AVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKE 64
Query: 77 QGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAG 136
QG SFWRGNLANVIRYFPTQALNFAFKDKYKQ+F+ GV+K QFW +F NLASGGAAG
Sbjct: 65 QGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAG 124
Query: 137 ATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGI 196
ATSLC VYPLDFARTRL D+GK ER+F+GLGDC++KI KSDGI GLYQGF VSVQGI
Sbjct: 125 ATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGI 184
Query: 197 IVYRASYFGAYDTVKGLLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGE 256
I+YRA+YFG YDT KG+LP PK T ++S+ IAQ VT +G+ SYPFDTVRRRMMMQSG
Sbjct: 185 IIYRAAYFGIYDTAKGMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGR 244
Query: 257 --AKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGGALVLVLYDKIKEF 307
Y GTLDC+ KI + EG +FF+GA+SNVLRG GGA VLVLYD+IK++
Sbjct: 245 KGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFVLVLYDEIKKY 297
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 132 bits (332), Expect = 4e-31
Identities = 94/294 (31%), Positives = 145/294 (49%), Gaps = 28/294 (9%)
Query: 22 KDLLAGGVAAAVSKTAVAPIERVKLLLQVQAS-SKQISPEARYKGMVDCLVRIPREQGFF 80
+ LLAGG+A AVS+T+ AP++R+K+++QV S S +++ ++ MV +E G
Sbjct: 196 RQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMV-------KEGGIR 248
Query: 81 SFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSL 140
S WRGN NVI+ P A+ F ++YK+L K F R+ SG AGAT+
Sbjct: 249 SLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFI-----SGSMAGATAQ 303
Query: 141 CVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYR 200
+YP++ +TRL V + Q+ G+ DC KI K +G+ Y+G+ ++ GII Y
Sbjct: 304 TFIYPMEVMKTRLAVG-----KTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYA 358
Query: 201 ASYFGAYDTVKGL----LPKPKKTP-FLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSG 255
Y+ +K K P +V + +TC + SYP VR RM Q+
Sbjct: 359 GIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAM 418
Query: 256 EAKRQYKGTLDCFVKIYQHEGISSFFRGA---FSNVLRGTGGALVLVLYDKIKE 306
+ F +I EGI +RG F VL G + V+Y+ +K+
Sbjct: 419 LEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVG--ISYVVYENMKQ 470
Score = 57.8 bits (138), Expect = 1e-08
Identities = 44/196 (22%), Positives = 86/196 (43%), Gaps = 12/196 (6%)
Query: 25 LAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSFWR 84
++G +A A ++T + P+E +K L V + + Y G+ DC +I + +G +F++
Sbjct: 293 ISGSMAGATAQTFIYPMEVMKTRLAVGKTGQ-------YSGIYDCAKKILKHEGLGAFYK 345
Query: 85 GNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVVY 144
G + N++ P ++ A + K ++ K+ + L G + Y
Sbjct: 346 GYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVN-PGVMVLLGCGALSSTCGQLASY 404
Query: 145 PLDFARTRLGVD-IGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRASY 203
PL RTR+ + +G + GL +I +GI GLY+G + ++
Sbjct: 405 PLALVRTRMQAQAMLEGSPQLNMVGL---FRRIISKEGIPGLYRGITPNFMKVLPAVGIS 461
Query: 204 FGAYDTVKGLLPKPKK 219
+ Y+ +K L +K
Sbjct: 462 YVVYENMKQTLGVTQK 477
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 132 bits (332), Expect = 4e-31
Identities = 94/294 (31%), Positives = 145/294 (49%), Gaps = 28/294 (9%)
Query: 22 KDLLAGGVAAAVSKTAVAPIERVKLLLQVQAS-SKQISPEARYKGMVDCLVRIPREQGFF 80
+ LLAGG+A AVS+T+ AP++R+K+++QV S S +++ ++ MV +E G
Sbjct: 177 RQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMV-------KEGGIR 229
Query: 81 SFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSL 140
S WRGN NVI+ P A+ F ++YK+L K F R+ SG AGAT+
Sbjct: 230 SLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFI-----SGSMAGATAQ 284
Query: 141 CVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYR 200
+YP++ +TRL V + Q+ G+ DC KI K +G+ Y+G+ ++ GII Y
Sbjct: 285 TFIYPMEVMKTRLAVG-----KTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYA 339
Query: 201 ASYFGAYDTVKGL----LPKPKKTP-FLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSG 255
Y+ +K K P +V + +TC + SYP VR RM Q+
Sbjct: 340 GIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAM 399
Query: 256 EAKRQYKGTLDCFVKIYQHEGISSFFRGA---FSNVLRGTGGALVLVLYDKIKE 306
+ F +I EGI +RG F VL G + V+Y+ +K+
Sbjct: 400 LEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVG--ISYVVYENMKQ 451
Score = 57.8 bits (138), Expect = 1e-08
Identities = 44/196 (22%), Positives = 86/196 (43%), Gaps = 12/196 (6%)
Query: 25 LAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSFWR 84
++G +A A ++T + P+E +K L V + + Y G+ DC +I + +G +F++
Sbjct: 274 ISGSMAGATAQTFIYPMEVMKTRLAVGKTGQ-------YSGIYDCAKKILKHEGLGAFYK 326
Query: 85 GNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVVY 144
G + N++ P ++ A + K ++ K+ + L G + Y
Sbjct: 327 GYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVN-PGVMVLLGCGALSSTCGQLASY 385
Query: 145 PLDFARTRLGVD-IGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRASY 203
PL RTR+ + +G + GL +I +GI GLY+G + ++
Sbjct: 386 PLALVRTRMQAQAMLEGSPQLNMVGL---FRRIISKEGIPGLYRGITPNFMKVLPAVGIS 442
Query: 204 FGAYDTVKGLLPKPKK 219
+ Y+ +K L +K
Sbjct: 443 YVVYENMKQTLGVTQK 458
>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
Length = 332
Score = 125 bits (313), Expect = 6e-29
Identities = 96/311 (30%), Positives = 144/311 (46%), Gaps = 37/311 (11%)
Query: 22 KDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFS 81
+ LAGG+A +KT VAP++RVK+LLQ + ++ G+ L +P+++GF
Sbjct: 38 RSFLAGGIAGCCAKTTVAPLDRVKVLLQAH------NHHYKHLGVFSALRAVPQKEGFLG 91
Query: 82 FWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLC 141
++GN A +IR FP A+ F + YK L + + R L +G AG T++
Sbjct: 92 LYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVHR-----LMAGSMAGMTAVI 146
Query: 142 VVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKI-AKSDGIAGLYQGFGVSVQGIIVYR 200
YPLD R RL + KG E + G+ I AK G G Y+G ++ G+ Y
Sbjct: 147 CTYPLDMVRVRLAFQV-KG--EHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYA 203
Query: 201 ASYFGAYDTVKG--------LLPKPKKTPFLVSFFIAQVVTTCSGI-------LSYPFDT 245
F + T+K LL +P V V C G+ +SYPFD
Sbjct: 204 GVSFFTFGTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAGAIAQTISYPFDV 263
Query: 246 VRRRMMMQSGEAKRQYKGTL---DCFVKIYQHEGI-SSFFRGAFSNVLRG-TGGALVLVL 300
RRR MQ G +++ L D +Y H GI +RG N +R A+
Sbjct: 264 TRRR--MQLGTVLPEFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTT 321
Query: 301 YDKIKEFFHID 311
Y+ +K+FFH++
Sbjct: 322 YELMKQFFHLN 332
Score = 57.0 bits (136), Expect = 2e-08
Identities = 46/170 (27%), Positives = 74/170 (43%), Gaps = 11/170 (6%)
Query: 124 WFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLG--DCIMKIAKSDG 181
++L + +GG AG + V PLD + L +K LG + + + +G
Sbjct: 35 YWLRSFLAGGIAGCCAKTTVAPLDRVKVLLQA------HNHHYKHLGVFSALRAVPQKEG 88
Query: 182 IAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKKTPFLVSFFIAQVVTTCSGIL-S 240
GLY+G G + I Y A F A++ K L+ V +A + + ++ +
Sbjct: 89 FLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVHRLMAGSMAGMTAVICT 148
Query: 241 YPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHE-GISSFFRGAFSNVL 289
YP D VR R+ Q + + Y G + F IY E G F+RG +L
Sbjct: 149 YPLDMVRVRLAFQV-KGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTIL 197
>gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
Length = 678
Score = 118 bits (295), Expect = 8e-27
Identities = 87/292 (29%), Positives = 131/292 (44%), Gaps = 17/292 (5%)
Query: 27 GGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSFWRGN 86
G VA AV TAV PI+ VK +Q Q S + E YK DC ++ R +GFF +RG
Sbjct: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGL 392
Query: 87 LANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVVYPL 146
+ +I P +A+ D + F A + +GG AG + + PL
Sbjct: 393 IPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVP-----LPAEVLAGGCAGGSQVIFTNPL 447
Query: 147 DFARTRLGV--DIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRASYF 204
+ + RL V +I GP L D GI GLY+G I + A YF
Sbjct: 448 EIVKIRLQVAGEITTGPRVSALNVLRDL--------GIFGLYKGAKACFLRDIPFSAIYF 499
Query: 205 GAYDTVKGLLPKPKKTPFLVSFFIAQVVT-TCSGILSYPFDTVRRRMMMQSGEAKRQYKG 263
Y K LL ++ A + + L P D ++ R+ + + + Y G
Sbjct: 500 PVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSG 559
Query: 264 TLDCFVKIYQHEGISSFFRGAFSNVLRGTGG-ALVLVLYDKIKEFFHIDIGG 314
+DCF KI + EG S+F++G + V R + + LV Y+ ++ +F+ID GG
Sbjct: 560 VIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGG 611
Score = 53.5 bits (127), Expect = 2e-07
Identities = 48/177 (27%), Positives = 76/177 (42%), Gaps = 27/177 (15%)
Query: 23 DLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSF 82
++LAGG A P+E VK+ LQV + +I+ R + + R+ G F
Sbjct: 429 EVLAGGCAGGSQVIFTNPLEIVKIRLQV---AGEITTGPRVSAL-----NVLRDLGIFGL 480
Query: 83 WRGNLANVIRYFPTQALNFAFKDKYKQLF------MSGVNKEKQFWRWFLANLASGGAAG 136
++G A +R P A+ F K L + G+N LA+G AG
Sbjct: 481 YKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNL-----------LAAGAMAG 529
Query: 137 ATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSV 193
+ +V P D +TRL V G + + G+ DC KI + +G + ++G V
Sbjct: 530 VPAASLVTPADVIKTRLQVAARAG--QTTYSGVIDCFRKILREEGPSAFWKGTAARV 584
>gi|60460887 solute carrier family 25, member 42 [Homo sapiens]
Length = 318
Score = 117 bits (294), Expect = 1e-26
Identities = 84/277 (30%), Positives = 142/277 (51%), Gaps = 27/277 (9%)
Query: 24 LLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSFW 83
LL G +A A++KTAVAP++R K++ QV SSK+ S + ++ + + +GF S W
Sbjct: 37 LLPGALAGALAKTAVAPLDRTKIIFQV--SSKRFSAKEAFRVLYYTYLN----EGFLSLW 90
Query: 84 RGNLANVIRYFPTQALNFAFKDKYKQLFMSGVN-KEKQFWRWFLANLASGGAAGATSLCV 142
RGN A ++R P A+ F+ ++YK++ S + + W L +G AG T+ +
Sbjct: 91 RGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPW--PRLFAGALAGTTAASL 148
Query: 143 VYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRAS 202
YPLD R R+ V P+E + + ++I++ +G+ LY GF +V G+I Y
Sbjct: 149 TYPLDLVRARMAVT----PKE-MYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGL 203
Query: 203 YFGAYDTVKGLLPK--PKKTPFLVSFFIAQVVTTCSGIL----SYPFDTVRRRMMMQ--S 254
F Y+T+K L + ++ P+ F + C+G++ SYP D VRRRM +
Sbjct: 204 SFFTYETLKSLHREYSGRRQPYP---FERMIFGACAGLIGQSASYPLDVVRRRMQTAGVT 260
Query: 255 GEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRG 291
G + TL V+ + + ++G N ++G
Sbjct: 261 GYPRASIARTLRTIVR--EEGAVRGLYKGLSMNWVKG 295
Score = 57.0 bits (136), Expect = 2e-08
Identities = 52/210 (24%), Positives = 88/210 (41%), Gaps = 14/210 (6%)
Query: 112 MSGVNKEKQFWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGD 171
+S K+ R L++L G AGA + V PLD + V + + F+ L
Sbjct: 20 LSSSVSSKRDHRQVLSSLLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYY 79
Query: 172 CIMKIAKSDGIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLP-----KPKKTPFLVSF 226
+ ++G L++G ++ ++ Y A F A++ K +L + + P
Sbjct: 80 TYL----NEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRL 135
Query: 227 FIAQVVTTCSGILSYPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFS 286
F + T + L+YP D VR RM + K Y F++I + EG+ + + G
Sbjct: 136 FAGALAGTTAASLTYPLDLVRARMAV---TPKEMYSNIFHVFIRISREEGLKTLYHGFMP 192
Query: 287 NVLRGTGGA-LVLVLYDKIKEFFHIDIGGR 315
VL A L Y+ +K H + GR
Sbjct: 193 TVLGVIPYAGLSFFTYETLKS-LHREYSGR 221
>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
sapiens]
Length = 675
Score = 117 bits (292), Expect = 2e-26
Identities = 83/292 (28%), Positives = 131/292 (44%), Gaps = 17/292 (5%)
Query: 27 GGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSFWRGN 86
G VA AV TAV PI+ VK +Q Q S+ E YK DC ++ R +GFF +RG
Sbjct: 335 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 394
Query: 87 LANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVVYPL 146
L ++ P +A+ D + FM K A + +GG AG + + PL
Sbjct: 395 LPQLLGVAPEKAIKLTVNDFVRDKFM-----HKDGSVPLAAEILAGGCAGGSQVIFTNPL 449
Query: 147 DFARTRLGV--DIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRASYF 204
+ + RL V +I GP + + + G G+Y+G I + A YF
Sbjct: 450 EIVKIRLQVAGEITTGPRV--------SALSVVRDLGFFGIYKGAKACFLRDIPFSAIYF 501
Query: 205 GAYDTVKGLLPKPKKTPFLVSFFIAQVVTTC-SGILSYPFDTVRRRMMMQSGEAKRQYKG 263
Y VK S +A + + L P D ++ R+ + + + Y G
Sbjct: 502 PCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSG 561
Query: 264 TLDCFVKIYQHEGISSFFRGAFSNVLRGTGG-ALVLVLYDKIKEFFHIDIGG 314
+DCF KI + EG + ++GA + V R + + L+ Y+ ++ +F+ID GG
Sbjct: 562 VIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWFYIDFGG 613
Score = 60.5 bits (145), Expect = 2e-09
Identities = 51/171 (29%), Positives = 79/171 (46%), Gaps = 15/171 (8%)
Query: 23 DLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSF 82
++LAGG A P+E VK+ LQV + +I+ R + + R+ GFF
Sbjct: 431 EILAGGCAGGSQVIFTNPLEIVKIRLQV---AGEITTGPRVSAL-----SVVRDLGFFGI 482
Query: 83 WRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCV 142
++G A +R P A+ F Y + S N++ Q L L +G AG + +
Sbjct: 483 YKGAKACFLRDIPFSAIYFPC---YAHVKASFANEDGQVSPGSL--LLAGAIAGMPAASL 537
Query: 143 VYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSV 193
V P D +TRL V G + + G+ DC KI + +G L++G G V
Sbjct: 538 VTPADVIKTRLQVAARAG--QTTYSGVIDCFRKILREEGPKALWKGAGARV 586
Score = 48.9 bits (115), Expect = 6e-06
Identities = 28/75 (37%), Positives = 41/75 (54%), Gaps = 4/75 (5%)
Query: 21 GKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFF 80
G LLAG +A + + V P + +K LQV A + Q + Y G++DC +I RE+G
Sbjct: 521 GSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTT----YSGVIDCFRKILREEGPK 576
Query: 81 SFWRGNLANVIRYFP 95
+ W+G A V R P
Sbjct: 577 ALWKGAGARVFRSSP 591
>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
sapiens]
Length = 676
Score = 117 bits (292), Expect = 2e-26
Identities = 83/292 (28%), Positives = 131/292 (44%), Gaps = 17/292 (5%)
Query: 27 GGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSFWRGN 86
G VA AV TAV PI+ VK +Q Q S+ E YK DC ++ R +GFF +RG
Sbjct: 336 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 395
Query: 87 LANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVVYPL 146
L ++ P +A+ D + FM K A + +GG AG + + PL
Sbjct: 396 LPQLLGVAPEKAIKLTVNDFVRDKFM-----HKDGSVPLAAEILAGGCAGGSQVIFTNPL 450
Query: 147 DFARTRLGV--DIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRASYF 204
+ + RL V +I GP + + + G G+Y+G I + A YF
Sbjct: 451 EIVKIRLQVAGEITTGPRV--------SALSVVRDLGFFGIYKGAKACFLRDIPFSAIYF 502
Query: 205 GAYDTVKGLLPKPKKTPFLVSFFIAQVVTTC-SGILSYPFDTVRRRMMMQSGEAKRQYKG 263
Y VK S +A + + L P D ++ R+ + + + Y G
Sbjct: 503 PCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSG 562
Query: 264 TLDCFVKIYQHEGISSFFRGAFSNVLRGTGG-ALVLVLYDKIKEFFHIDIGG 314
+DCF KI + EG + ++GA + V R + + L+ Y+ ++ +F+ID GG
Sbjct: 563 VIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWFYIDFGG 614
Score = 60.5 bits (145), Expect = 2e-09
Identities = 51/171 (29%), Positives = 79/171 (46%), Gaps = 15/171 (8%)
Query: 23 DLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSF 82
++LAGG A P+E VK+ LQV + +I+ R + + R+ GFF
Sbjct: 432 EILAGGCAGGSQVIFTNPLEIVKIRLQV---AGEITTGPRVSAL-----SVVRDLGFFGI 483
Query: 83 WRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCV 142
++G A +R P A+ F Y + S N++ Q L L +G AG + +
Sbjct: 484 YKGAKACFLRDIPFSAIYFPC---YAHVKASFANEDGQVSPGSL--LLAGAIAGMPAASL 538
Query: 143 VYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSV 193
V P D +TRL V G + + G+ DC KI + +G L++G G V
Sbjct: 539 VTPADVIKTRLQVAARAG--QTTYSGVIDCFRKILREEGPKALWKGAGARV 587
Score = 48.9 bits (115), Expect = 6e-06
Identities = 28/75 (37%), Positives = 41/75 (54%), Gaps = 4/75 (5%)
Query: 21 GKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFF 80
G LLAG +A + + V P + +K LQV A + Q + Y G++DC +I RE+G
Sbjct: 522 GSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTT----YSGVIDCFRKILREEGPK 577
Query: 81 SFWRGNLANVIRYFP 95
+ W+G A V R P
Sbjct: 578 ALWKGAGARVFRSSP 592
>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
Length = 468
Score = 116 bits (291), Expect = 2e-26
Identities = 86/291 (29%), Positives = 135/291 (46%), Gaps = 22/291 (7%)
Query: 22 KDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFS 81
K L+AG VA AVS+T AP++R+K+ +QV AS + ++ L + E G S
Sbjct: 187 KQLVAGAVAGAVSRTGTAPLDRLKVFMQVHAS------KTNRLNILGGLRSMVLEGGIRS 240
Query: 82 FWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLC 141
WRGN NV++ P A+ F ++ K+ + G + F+A G AGAT+
Sbjct: 241 LWRGNGINVLKIAPESAIKFMAYEQIKRAIL-GQQETLHVQERFVA----GSLAGATAQT 295
Query: 142 VVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRA 201
++YP++ +TRL + Q+KGL DC +I + +G Y+G+ +V GII Y
Sbjct: 296 IIYPMEVLKTRLTL-----RRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAG 350
Query: 202 SYFGAYDTVKG-----LLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGE 256
Y+T+K LV + +TC I SYP VR RM Q+
Sbjct: 351 IDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASI 410
Query: 257 AKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGG-ALVLVLYDKIKE 306
L I EG+ +RG N ++ ++ V+Y+ +K+
Sbjct: 411 EGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQ 461
Score = 65.9 bits (159), Expect = 5e-11
Identities = 54/194 (27%), Positives = 92/194 (47%), Gaps = 10/194 (5%)
Query: 117 KEKQFWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKI 176
+EK W+ L +G AGA S PLD + + V K GL +++
Sbjct: 178 QEKLTGMWW-KQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLE- 235
Query: 177 AKSDGIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKKTPFLVSFFIA-QVVTTC 235
GI L++G G++V I A F AY+ +K + ++T + F+A +
Sbjct: 236 ---GGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGAT 292
Query: 236 SGILSYPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGGA 295
+ + YP + ++ R+ ++ QYKG LDC +I + EG +F+RG NVL A
Sbjct: 293 AQTIIYPMEVLKTRLTLR---RTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYA 349
Query: 296 -LVLVLYDKIKEFF 308
+ L +Y+ +K ++
Sbjct: 350 GIDLAVYETLKNWW 363
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 116 bits (290), Expect = 3e-26
Identities = 83/290 (28%), Positives = 137/290 (47%), Gaps = 22/290 (7%)
Query: 22 KDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFS 81
+ L+AGG A AVS+T AP++R+K+L+QV AS + G+V ++ RE G S
Sbjct: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS------RSNNMGIVGGFTQMIREGGARS 241
Query: 82 FWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLC 141
WRGN NV++ P A+ F ++ K+L V +++ R L +G AGA +
Sbjct: 242 LWRGNGINVLKIAPESAIKFMAYEQIKRL----VGSDQETLR-IHERLVAGSLAGAIAQS 296
Query: 142 VVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRA 201
+YP++ +TR+ + + Q+ G+ DC +I +G+A Y+G+ ++ GII Y
Sbjct: 297 SIYPMEVLKTRMAL-----RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
Query: 202 SYFGAYDTVKG-----LLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGE 256
Y+T+K V + +TC + SYP VR RM Q+
Sbjct: 352 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 411
Query: 257 AKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGG-ALVLVLYDKIK 305
F I + EG +RG N ++ ++ V+Y+ +K
Sbjct: 412 EGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
Score = 62.0 bits (149), Expect = 7e-10
Identities = 49/177 (27%), Positives = 84/177 (47%), Gaps = 15/177 (8%)
Query: 117 KEKQFWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKI 176
+E+Q W+ +A GG AGA S PLD + + V + G+ ++
Sbjct: 179 EERQTGMWWRHLVA-GGGAGAVSRTCTAPLDRLKVLMQVHASRSNN----MGIVGGFTQM 233
Query: 177 AKSDGIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKKT----PFLVSFFIAQVV 232
+ G L++G G++V I A F AY+ +K L+ ++T LV+ +A +
Sbjct: 234 IREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAI 293
Query: 233 TTCSGILSYPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVL 289
S YP + ++ RM ++ QY G LDC +I EG+++F++G N+L
Sbjct: 294 AQSS---IYPMEVLKTRMALRK---TGQYSGMLDCARRILAREGVAAFYKGYVPNML 344
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 116 bits (290), Expect = 3e-26
Identities = 83/290 (28%), Positives = 137/290 (47%), Gaps = 22/290 (7%)
Query: 22 KDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFS 81
+ L+AGG A AVS+T AP++R+K+L+QV AS + G+V ++ RE G S
Sbjct: 222 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS------RSNNMGIVGGFTQMIREGGARS 275
Query: 82 FWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLC 141
WRGN NV++ P A+ F ++ K+L V +++ R L +G AGA +
Sbjct: 276 LWRGNGINVLKIAPESAIKFMAYEQIKRL----VGSDQETLR-IHERLVAGSLAGAIAQS 330
Query: 142 VVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRA 201
+YP++ +TR+ + + Q+ G+ DC +I +G+A Y+G+ ++ GII Y
Sbjct: 331 SIYPMEVLKTRMAL-----RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 385
Query: 202 SYFGAYDTVKG-----LLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGE 256
Y+T+K V + +TC + SYP VR RM Q+
Sbjct: 386 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 445
Query: 257 AKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGG-ALVLVLYDKIK 305
F I + EG +RG N ++ ++ V+Y+ +K
Sbjct: 446 EGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
Score = 62.0 bits (149), Expect = 7e-10
Identities = 49/177 (27%), Positives = 84/177 (47%), Gaps = 15/177 (8%)
Query: 117 KEKQFWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKI 176
+E+Q W+ +A GG AGA S PLD + + V + G+ ++
Sbjct: 213 EERQTGMWWRHLVA-GGGAGAVSRTCTAPLDRLKVLMQVHASRSNN----MGIVGGFTQM 267
Query: 177 AKSDGIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKKT----PFLVSFFIAQVV 232
+ G L++G G++V I A F AY+ +K L+ ++T LV+ +A +
Sbjct: 268 IREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAI 327
Query: 233 TTCSGILSYPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVL 289
S YP + ++ RM ++ QY G LDC +I EG+++F++G N+L
Sbjct: 328 AQSS---IYPMEVLKTRMALRK---TGQYSGMLDCARRILAREGVAAFYKGYVPNML 378
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 116 bits (290), Expect = 3e-26
Identities = 83/290 (28%), Positives = 137/290 (47%), Gaps = 22/290 (7%)
Query: 22 KDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFS 81
+ L+AGG A AVS+T AP++R+K+L+QV AS + G+V ++ RE G S
Sbjct: 208 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS------RSNNMGIVGGFTQMIREGGARS 261
Query: 82 FWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLC 141
WRGN NV++ P A+ F ++ K+L V +++ R L +G AGA +
Sbjct: 262 LWRGNGINVLKIAPESAIKFMAYEQIKRL----VGSDQETLR-IHERLVAGSLAGAIAQS 316
Query: 142 VVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRA 201
+YP++ +TR+ + + Q+ G+ DC +I +G+A Y+G+ ++ GII Y
Sbjct: 317 SIYPMEVLKTRMAL-----RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 371
Query: 202 SYFGAYDTVKG-----LLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGE 256
Y+T+K V + +TC + SYP VR RM Q+
Sbjct: 372 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 431
Query: 257 AKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGG-ALVLVLYDKIK 305
F I + EG +RG N ++ ++ V+Y+ +K
Sbjct: 432 EGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 481
Score = 62.0 bits (149), Expect = 7e-10
Identities = 49/177 (27%), Positives = 84/177 (47%), Gaps = 15/177 (8%)
Query: 117 KEKQFWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKI 176
+E+Q W+ +A GG AGA S PLD + + V + G+ ++
Sbjct: 199 EERQTGMWWRHLVA-GGGAGAVSRTCTAPLDRLKVLMQVHASRSNN----MGIVGGFTQM 253
Query: 177 AKSDGIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKKT----PFLVSFFIAQVV 232
+ G L++G G++V I A F AY+ +K L+ ++T LV+ +A +
Sbjct: 254 IREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAI 313
Query: 233 TTCSGILSYPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVL 289
S YP + ++ RM ++ QY G LDC +I EG+++F++G N+L
Sbjct: 314 AQSS---IYPMEVLKTRMALRK---TGQYSGMLDCARRILAREGVAAFYKGYVPNML 364
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 116 bits (290), Expect = 3e-26
Identities = 83/290 (28%), Positives = 137/290 (47%), Gaps = 22/290 (7%)
Query: 22 KDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFS 81
+ L+AGG A AVS+T AP++R+K+L+QV AS + G+V ++ RE G S
Sbjct: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS------RSNNMGIVGGFTQMIREGGARS 241
Query: 82 FWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLC 141
WRGN NV++ P A+ F ++ K+L V +++ R L +G AGA +
Sbjct: 242 LWRGNGINVLKIAPESAIKFMAYEQIKRL----VGSDQETLR-IHERLVAGSLAGAIAQS 296
Query: 142 VVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRA 201
+YP++ +TR+ + + Q+ G+ DC +I +G+A Y+G+ ++ GII Y
Sbjct: 297 SIYPMEVLKTRMAL-----RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
Query: 202 SYFGAYDTVKG-----LLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGE 256
Y+T+K V + +TC + SYP VR RM Q+
Sbjct: 352 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 411
Query: 257 AKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGG-ALVLVLYDKIK 305
F I + EG +RG N ++ ++ V+Y+ +K
Sbjct: 412 EGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
Score = 62.0 bits (149), Expect = 7e-10
Identities = 49/177 (27%), Positives = 84/177 (47%), Gaps = 15/177 (8%)
Query: 117 KEKQFWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKI 176
+E+Q W+ +A GG AGA S PLD + + V + G+ ++
Sbjct: 179 EERQTGMWWRHLVA-GGGAGAVSRTCTAPLDRLKVLMQVHASRSNN----MGIVGGFTQM 233
Query: 177 AKSDGIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKKT----PFLVSFFIAQVV 232
+ G L++G G++V I A F AY+ +K L+ ++T LV+ +A +
Sbjct: 234 IREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAI 293
Query: 233 TTCSGILSYPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVL 289
S YP + ++ RM ++ QY G LDC +I EG+++F++G N+L
Sbjct: 294 AQSS---IYPMEVLKTRMALRK---TGQYSGMLDCARRILAREGVAAFYKGYVPNML 344
>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
sapiens]
Length = 366
Score = 116 bits (290), Expect = 3e-26
Identities = 83/290 (28%), Positives = 137/290 (47%), Gaps = 22/290 (7%)
Query: 22 KDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFS 81
+ L+AGG A AVS+T AP++R+K+L+QV AS + G+V ++ RE G S
Sbjct: 85 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS------RSNNMGIVGGFTQMIREGGARS 138
Query: 82 FWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLC 141
WRGN NV++ P A+ F ++ K+L V +++ R L +G AGA +
Sbjct: 139 LWRGNGINVLKIAPESAIKFMAYEQIKRL----VGSDQETLR-IHERLVAGSLAGAIAQS 193
Query: 142 VVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRA 201
+YP++ +TR+ + + Q+ G+ DC +I +G+A Y+G+ ++ GII Y
Sbjct: 194 SIYPMEVLKTRMAL-----RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 248
Query: 202 SYFGAYDTVKG-----LLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGE 256
Y+T+K V + +TC + SYP VR RM Q+
Sbjct: 249 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 308
Query: 257 AKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGG-ALVLVLYDKIK 305
F I + EG +RG N ++ ++ V+Y+ +K
Sbjct: 309 EGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 358
Score = 62.0 bits (149), Expect = 7e-10
Identities = 49/177 (27%), Positives = 84/177 (47%), Gaps = 15/177 (8%)
Query: 117 KEKQFWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKI 176
+E+Q W+ +A GG AGA S PLD + + V + G+ ++
Sbjct: 76 EERQTGMWWRHLVA-GGGAGAVSRTCTAPLDRLKVLMQVHASRSNN----MGIVGGFTQM 130
Query: 177 AKSDGIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKKT----PFLVSFFIAQVV 232
+ G L++G G++V I A F AY+ +K L+ ++T LV+ +A +
Sbjct: 131 IREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAI 190
Query: 233 TTCSGILSYPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVL 289
S YP + ++ RM ++ QY G LDC +I EG+++F++G N+L
Sbjct: 191 AQSS---IYPMEVLKTRMALRK---TGQYSGMLDCARRILAREGVAAFYKGYVPNML 241
>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
sapiens]
Length = 503
Score = 116 bits (290), Expect = 3e-26
Identities = 83/290 (28%), Positives = 137/290 (47%), Gaps = 22/290 (7%)
Query: 22 KDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFS 81
+ L+AGG A AVS+T AP++R+K+L+QV AS + G+V ++ RE G S
Sbjct: 222 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS------RSNNMGIVGGFTQMIREGGARS 275
Query: 82 FWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLC 141
WRGN NV++ P A+ F ++ K+L V +++ R L +G AGA +
Sbjct: 276 LWRGNGINVLKIAPESAIKFMAYEQIKRL----VGSDQETLR-IHERLVAGSLAGAIAQS 330
Query: 142 VVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRA 201
+YP++ +TR+ + + Q+ G+ DC +I +G+A Y+G+ ++ GII Y
Sbjct: 331 SIYPMEVLKTRMAL-----RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 385
Query: 202 SYFGAYDTVKG-----LLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGE 256
Y+T+K V + +TC + SYP VR RM Q+
Sbjct: 386 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 445
Query: 257 AKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGG-ALVLVLYDKIK 305
F I + EG +RG N ++ ++ V+Y+ +K
Sbjct: 446 EGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
Score = 62.0 bits (149), Expect = 7e-10
Identities = 49/177 (27%), Positives = 84/177 (47%), Gaps = 15/177 (8%)
Query: 117 KEKQFWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKI 176
+E+Q W+ +A GG AGA S PLD + + V + G+ ++
Sbjct: 213 EERQTGMWWRHLVA-GGGAGAVSRTCTAPLDRLKVLMQVHASRSNN----MGIVGGFTQM 267
Query: 177 AKSDGIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKKT----PFLVSFFIAQVV 232
+ G L++G G++V I A F AY+ +K L+ ++T LV+ +A +
Sbjct: 268 IREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAI 327
Query: 233 TTCSGILSYPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVL 289
S YP + ++ RM ++ QY G LDC +I EG+++F++G N+L
Sbjct: 328 AQSS---IYPMEVLKTRMALRK---TGQYSGMLDCARRILAREGVAAFYKGYVPNML 378
>gi|149274607 solute carrier family 25, member 41 [Homo sapiens]
Length = 370
Score = 110 bits (275), Expect = 2e-24
Identities = 86/292 (29%), Positives = 140/292 (47%), Gaps = 26/292 (8%)
Query: 22 KDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFS 81
K LL+G +A AVS+T AP++R K+ +QV +S + + ++ L + +E GF S
Sbjct: 94 KFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSS------KTNFTNLLGGLQSMVQEGGFRS 147
Query: 82 FWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLC 141
WRGN NV++ P A+ F+ ++ K F G+ F LA G A A S
Sbjct: 148 LWRGNGINVLKIAPEYAIKFSVFEQCKNYFC-GIQGSPPFQERLLA----GSLAVAISQT 202
Query: 142 VVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRA 201
++ P++ +TRL + Q+KGL DC +I + +G LY+G+ ++ GII Y
Sbjct: 203 LINPMEVLKTRLTLR-----RTGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYAC 257
Query: 202 SYFGAYDTVKGLLPKPKK----TPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQS--G 255
+ Y+ ++ K + LVS + TTC + SYP VR RM Q
Sbjct: 258 TDLAVYEMLQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTVE 317
Query: 256 EAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRG-TGGALVLVLYDKIKE 306
+ +G L +I +G +RG +L+ G + V+Y+ +K+
Sbjct: 318 GSNPTMRGVLQ---RILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
Score = 56.2 bits (134), Expect = 4e-08
Identities = 50/206 (24%), Positives = 87/206 (42%), Gaps = 34/206 (16%)
Query: 20 FGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGF 79
F + LLAG +A A+S+T + P+E +K L ++ + +YKG++DC +I + +G
Sbjct: 186 FQERLLAGSLAVAISQTLINPMEVLKTRLTLRRT-------GQYKGLLDCARQILQREGT 238
Query: 80 FSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATS 139
+ +RG L N++ P + A + Q F W + G +G S
Sbjct: 239 RALYRGYLPNMLGIIPYACTDLAVYEML-QCF------------WVKSGRDMGDPSGLVS 285
Query: 140 LCVV-----------YPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQG 188
L V YPL RTR+ +G+ + +I G GLY+G
Sbjct: 286 LSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEGSNPTMRGV---LQRILAQQGWLGLYRG 342
Query: 189 FGVSVQGIIVYRASYFGAYDTVKGLL 214
++ ++ + Y+ +K L
Sbjct: 343 MTPTLLKVLPAGGISYVVYEAMKKTL 368
>gi|13375983 mitochondrial glutamate carrier 1 [Homo sapiens]
Length = 323
Score = 109 bits (273), Expect = 3e-24
Identities = 82/293 (27%), Positives = 132/293 (45%), Gaps = 38/293 (12%)
Query: 24 LLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSFW 83
L+ GG+A + T V PI+ K LQ Q + +++ Y M DCL++ R +G+F +
Sbjct: 12 LINGGIAGLIGVTCVFPIDLAKTRLQNQQNGQRV-----YTSMSDCLIKTVRSEGYFGMY 66
Query: 84 RGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVV 143
RG N+ P +A+ A D F ++K+ Q L + +G AG + V
Sbjct: 67 RGAAVNLTLVTPEKAIKLAAND----FFRHQLSKDGQKLT-LLKEMLAGCGAGTCQVIVT 121
Query: 144 YPLDFARTRLGVDIGKGPEER-------QFKGLGDC-----------------IMKIAKS 179
P++ + +L D G+ +R Q G + +S
Sbjct: 122 TPMEMLKIQLQ-DAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRPTATQLTRDLLRS 180
Query: 180 DGIAGLYQGFGVSVQGIIVYRASYFGAYDTVK--GLLPKPKKTPFLVSFFIAQVVTTCSG 237
GIAGLY+G G ++ + + YF + + G +K+PF VSF V + +
Sbjct: 181 RGIAGLYKGLGATLLRDVPFSVVYFPLFANLNQLGRPASEEKSPFYVSFLAGCVAGSAAA 240
Query: 238 ILSYPFDTVRRRMM-MQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVL 289
+ P D V+ R+ +Q G + Y G LDC KI +HEG S+F +GA+ L
Sbjct: 241 VAVNPCDVVKTRLQSLQRGVNEDTYSGILDCARKILRHEGPSAFLKGAYCRAL 293
Score = 55.1 bits (131), Expect = 8e-08
Identities = 34/122 (27%), Positives = 60/122 (49%), Gaps = 4/122 (3%)
Query: 127 ANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLY 186
A L +GG AG + V+P+D A+TRL + +R + + DC++K +S+G G+Y
Sbjct: 10 AKLINGGIAGLIGVTCVFPIDLAKTRLQ---NQQNGQRVYTSMSDCLIKTVRSEGYFGMY 66
Query: 187 QGFGVSVQGIIVYRASYFGAYDTVKGLLPKP-KKTPFLVSFFIAQVVTTCSGILSYPFDT 245
+G V++ + +A A D + L K +K L TC I++ P +
Sbjct: 67 RGAAVNLTLVTPEKAIKLAANDFFRHQLSKDGQKLTLLKEMLAGCGAGTCQVIVTTPMEM 126
Query: 246 VR 247
++
Sbjct: 127 LK 128
Score = 53.1 bits (126), Expect = 3e-07
Identities = 56/229 (24%), Positives = 95/229 (41%), Gaps = 43/229 (18%)
Query: 22 KDLLAGGVAAAVSKTAVAPIERVKLLLQ----------VQASSKQISPEARYKGMVDC-- 69
K++LAG A P+E +K+ LQ + A+ Q+S + + V+
Sbjct: 105 KEMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPA 164
Query: 70 --------LVR-IPREQGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQ 120
L R + R +G ++G A ++R P + F QL ++
Sbjct: 165 APRPTATQLTRDLLRSRGIAGLYKGLGATLLRDVPFSVVYFPLFANLNQLGRPASEEKSP 224
Query: 121 FWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSD 180
F+ FLA +G AA V P D +TRL + +G E + G+ DC KI + +
Sbjct: 225 FYVSFLAGCVAGSAAAVA----VNPCDVVKTRL-QSLQRGVNEDTYSGILDCARKILRHE 279
Query: 181 GIAGLYQG-----------FGVSVQGIIVYRASYFGAYDTVKGLLPKPK 218
G + +G FG++ +VY + G +++ GLL P+
Sbjct: 280 GPSAFLKGAYCRALVIAPLFGIAQ---VVY---FLGIAESLLGLLQDPQ 322
Score = 37.0 bits (84), Expect = 0.023
Identities = 25/70 (35%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
Query: 16 DASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPR 75
+ S F LAG VA + + AV P + VK LQ S ++ E Y G++DC +I R
Sbjct: 221 EKSPFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQ---SLQRGVNEDTYSGILDCARKILR 277
Query: 76 EQGFFSFWRG 85
+G +F +G
Sbjct: 278 HEGPSAFLKG 287
>gi|21687151 mitochondrial solute carrier protein [Homo sapiens]
Length = 341
Score = 102 bits (254), Expect = 4e-22
Identities = 78/280 (27%), Positives = 128/280 (45%), Gaps = 27/280 (9%)
Query: 21 GKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFF 80
G+ LL G+A +S + AP+E +L QV +G R+ R +G
Sbjct: 13 GQRLLCAGLAGTLSLSLTAPLELATVLAQVGVV------RGHARGPWATGHRVWRAEGLR 66
Query: 81 SFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSL 140
+ W+GN +R FP A+ A K+ LF + Q+ +++ +G AG S
Sbjct: 67 ALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQW-----SSIMAGSLAGMVST 121
Query: 141 CVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYR 200
V YP D +TRL I + E ++GL I + +G LY+G ++V G + +
Sbjct: 122 IVTYPTDLIKTRL---IMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFS 178
Query: 201 ASYFGAYDTVKGLLPKPKKTPFLVSFF----IAQVVTTCSGILSYPFDTVRRRMMMQ--- 253
A Y ++ + P+ L F +A VT LS+PF+TV+R+M Q
Sbjct: 179 AGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQ---TLSFPFETVKRKMQAQSPY 235
Query: 254 ---SGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLR 290
SG + G +DCF +I + +G+ + G +N+L+
Sbjct: 236 LPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLK 275
Score = 50.8 bits (120), Expect = 2e-06
Identities = 44/192 (22%), Positives = 78/192 (40%), Gaps = 14/192 (7%)
Query: 24 LLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSFW 83
++AG +A VS P + +K L +Q E Y+G++ I +++GF + +
Sbjct: 110 IMAGSLAGMVSTIVTYPTDLIKTRLIMQNIL-----EPSYRGLLHAFSTIYQQEGFLALY 164
Query: 84 RGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVV 143
RG V+ P A + Y L QF N A+ A A + +
Sbjct: 165 RGVSLTVVGALPFSAGSLLV---YMNLEKIWNGPRDQFS--LPQNFANVCLAAAVTQTLS 219
Query: 144 YPLDFARTRLGVDIG----KGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVY 199
+P + + ++ G + F G DC +I K+ G+ GL+ G ++ I+ Y
Sbjct: 220 FPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPY 279
Query: 200 RASYFGAYDTVK 211
F ++ K
Sbjct: 280 FGIMFSTFEFCK 291
>gi|13899342 solute carrier [Homo sapiens]
Length = 315
Score = 102 bits (253), Expect = 6e-22
Identities = 84/316 (26%), Positives = 136/316 (43%), Gaps = 42/316 (13%)
Query: 24 LLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSFW 83
L+ GGVA V T V PI+ K LQ Q +A YKGM+DCL++ R +GFF +
Sbjct: 12 LINGGVAGLVGVTCVFPIDLAKTRLQNQHG------KAMYKGMIDCLMKTARAEGFFGMY 65
Query: 84 RGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVV 143
RG N+ P +A+ A D +++L M E R + +G AG + V
Sbjct: 66 RGAAVNLTLVTPEKAIKLAANDFFRRLLM-----EDGMQRNLKMEMLAGCGAGMCQVVVT 120
Query: 144 YPLDFARTRLGVDIGK----------GPEERQFKGLGDC-----------IMKIAKSDGI 182
P++ + +L D G+ P + G ++ ++ G+
Sbjct: 121 CPMEMLKIQL-QDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGL 179
Query: 183 AGLYQGFGVSVQGIIVYRASYFGAYDTVK--GLLPKPKKTPFLVSFFIAQVVTTCSGILS 240
AGLY+G G ++ I + YF + + G K F SF V + + +
Sbjct: 180 AGLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAV 239
Query: 241 YPFDTVRRRMM-MQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGGALVLV 299
P D ++ R+ ++ G + Y G DC K++ EG S+F +GA G ++
Sbjct: 240 TPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGA------GCRALVIAP 293
Query: 300 LYDKIKEFFHIDIGGR 315
L+ + + I IG R
Sbjct: 294 LFGIAQGVYFIGIGER 309
Score = 61.2 bits (147), Expect = 1e-09
Identities = 52/190 (27%), Positives = 84/190 (44%), Gaps = 33/190 (17%)
Query: 127 ANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLY 186
A L +GG AG + V+P+D A+TRL GK +KG+ DC+MK A+++G G+Y
Sbjct: 10 AKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKA----MYKGMIDCLMKTARAEGFFGMY 65
Query: 187 QGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKKTPFLVSFFIA-------QVVTTC---- 235
+G V++ + +A A D + LL + L +A QVV TC
Sbjct: 66 RGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPMEM 125
Query: 236 ---------------SGILSYPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSF 280
G S P + R S R+ TL + ++ + +G++
Sbjct: 126 LKIQLQDAGRLAVHHQGSASAP--STSRSYTTGSASTHRRPSATLIAW-ELLRTQGLAGL 182
Query: 281 FRGAFSNVLR 290
+RG + +LR
Sbjct: 183 YRGLGATLLR 192
Score = 45.1 bits (105), Expect = 8e-05
Identities = 47/186 (25%), Positives = 72/186 (38%), Gaps = 23/186 (12%)
Query: 23 DLLAGGVAAAVSKTAVAPIERVKLLLQV--------QASSKQISPEARYKGMVDCLVRIP 74
++LAG A P+E +K+ LQ Q S+ S Y R P
Sbjct: 105 EMLAGCGAGMCQVVVTCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRP 164
Query: 75 ----------REQGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRW 124
R QG +RG A ++R P + F L + + + F
Sbjct: 165 SATLIAWELLRTQGLAGLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHS 224
Query: 125 FLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAG 184
F+ SG AG+ + V PLD +TR+ + KG E + G+ DC K+ +G +
Sbjct: 225 FV----SGCVAGSIAAVAVTPLDVLKTRIQT-LKKGLGEDMYSGITDCARKLWIQEGPSA 279
Query: 185 LYQGFG 190
+G G
Sbjct: 280 FMKGAG 285
Score = 34.7 bits (78), Expect = 0.11
Identities = 19/68 (27%), Positives = 38/68 (55%), Gaps = 3/68 (4%)
Query: 18 SSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQ 77
+SF ++G VA +++ AV P++ +K +Q + K+ E Y G+ DC ++ ++
Sbjct: 219 ASFAHSFVSGCVAGSIAAVAVTPLDVLKTRIQ---TLKKGLGEDMYSGITDCARKLWIQE 275
Query: 78 GFFSFWRG 85
G +F +G
Sbjct: 276 GPSAFMKG 283
>gi|21314739 solute carrier family 25, member 32 [Homo sapiens]
Length = 315
Score = 97.4 bits (241), Expect = 1e-20
Identities = 79/296 (26%), Positives = 137/296 (46%), Gaps = 23/296 (7%)
Query: 22 KDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFS 81
++L+AG +S A+ P++ VK+ V S + +Y G++ CL I + G
Sbjct: 24 ENLIAGVSGGVLSNLALHPLDLVKIRFAV---SDGLELRPKYNGILHCLTTIWKLDGLRG 80
Query: 82 FWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLC 141
++G N+ + L F F + K G + + + L S AGA +LC
Sbjct: 81 LYQGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLEATEY----LVSAAEAGAMTLC 136
Query: 142 VVYPLDFARTRLGV--DIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVY 199
+ PL +TRL + D RQ+KG+ D ++KI K +G+ GLY+GF + G +
Sbjct: 137 ITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYKGFVPGLFGTS-H 195
Query: 200 RASYFGAYDTVK-------GLLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMM 252
A F AY+ +K LP+ + + + +A + + +YP+ VR R+
Sbjct: 196 GALQFMAYELLKLKYNQHINRLPEAQLST-VEYISVAALSKIFAVAATYPYQVVRARLQD 254
Query: 253 QSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGG-ALVLVLYDKIKEF 307
Q Y G +D K ++ EG+ F++G N++R T + V+Y+ + F
Sbjct: 255 QH----MFYSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYENVSHF 306
Score = 49.3 bits (116), Expect = 4e-06
Identities = 43/193 (22%), Positives = 80/193 (41%), Gaps = 11/193 (5%)
Query: 24 LLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSFW 83
L++ A A++ P+ K L +Q + SP +YKGM D LV+I + +G +
Sbjct: 124 LVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLY 183
Query: 84 RGNLANVIRYFPTQ--ALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLC 141
+G + + F T AL F + K + +N+ + + ++ + ++
Sbjct: 184 KGFVPGL---FGTSHGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVA 240
Query: 142 VVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRA 201
YP R RL + + G+ D I K + +G+ G Y+G ++ +
Sbjct: 241 ATYPYQVVRARL------QDQHMFYSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACC 294
Query: 202 SYFGAYDTVKGLL 214
F Y+ V L
Sbjct: 295 ITFVVYENVSHFL 307
Score = 32.0 bits (71), Expect = 0.73
Identities = 24/93 (25%), Positives = 39/93 (41%), Gaps = 12/93 (12%)
Query: 31 AAVSK----TAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSFWRGN 86
AA+SK A P + V+ LQ Q Y G++D + + R++G F++G
Sbjct: 231 AALSKIFAVAATYPYQVVRARLQDQ--------HMFYSGVIDVITKTWRKEGVGGFYKGI 282
Query: 87 LANVIRYFPTQALNFAFKDKYKQLFMSGVNKEK 119
N+IR P + F + + K K
Sbjct: 283 APNLIRVTPACCITFVVYENVSHFLLDLREKRK 315
>gi|13449279 solute carrier family 25 (mitochondrial
oxodicarboxylate carrier), member 21 [Homo sapiens]
Length = 299
Score = 95.9 bits (237), Expect = 4e-20
Identities = 76/285 (26%), Positives = 133/285 (46%), Gaps = 14/285 (4%)
Query: 22 KDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFS 81
+ ++AGG A V + P++ VK Q+Q + + YK +VD I + +G F
Sbjct: 15 RQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNS---YKSLVDSFRMIFQMEGLFG 71
Query: 82 FWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLC 141
F++G L ++ P +A+ F ++YK+L G + +A L S G T
Sbjct: 72 FYKGILPPILAETPKRAVKFFTFEQYKKLL--GYVSLSPALTFAIAGLGS----GLTEAI 125
Query: 142 VVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRA 201
VV P + + L + E+ G I+K + G+ GL +G ++ V+
Sbjct: 126 VVNPFEVVKVGLQANRNTFAEQPSTVGYARQIIK-KEGWGLQGLNKGLTATLGRHGVFNM 184
Query: 202 SYFGAYDTVKGLLP--KPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMM-MQSGEAK 258
YFG Y VK ++P K F F I + T + +++ PFD + R+ Q +
Sbjct: 185 VYFGFYYNVKNMIPVNKDPILEFWRKFGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGE 244
Query: 259 RQYKGTLDCFVKIYQHEGISSFFRGAFSNVLR-GTGGALVLVLYD 302
+Y+ +YQ EGI + ++G ++R G GGA++L++Y+
Sbjct: 245 IKYRTCFKTMATVYQEEGILALYKGLLPKIMRLGPGGAVMLLVYE 289
>gi|108860679 solute carrier family 25, member 27 [Homo sapiens]
Length = 323
Score = 95.1 bits (235), Expect = 7e-20
Identities = 79/298 (26%), Positives = 139/298 (46%), Gaps = 21/298 (7%)
Query: 25 LAGGVAAAVSKTAVAPIERVKLLLQVQ--ASSKQISPEAR----YKGMVDCLVRIPREQG 78
L G AA V++ A P++ K LQ+Q A+ ++ AR Y+GMV + I E+G
Sbjct: 24 LLSGCAATVAELATFPLDLTKTRLQMQGEAALARLGDGARESAPYRGMVRTALGIIEEEG 83
Query: 79 FFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGAT 138
F W+G + R+ + +++ G ++++ + W ++ G AG
Sbjct: 84 FLKLWQGVTPAIYRHVVYSGGRMVTYEHLREVVF-GKSEDEHYPLW--KSVIGGMMAGVI 140
Query: 139 SLCVVYPLDFARTRLGVDIGKGPEER--QFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGI 196
+ P D + ++ ++ + E + +F+G+ KI GI GL+ G+ ++Q
Sbjct: 141 GQFLANPTDLVKVQMQMEGKRKLEGKPLRFRGVHHAFAKILAEGGIRGLWAGWVPNIQRA 200
Query: 197 IVYRASYFGAYDTVKGLLPKPKKTPFLVSFFIAQVVTTCSG----ILSYPFDTVRRRMMM 252
+ YDTVK L TP + + + CSG IL P D ++ R+M
Sbjct: 201 ALVNMGDLTTYDTVKHYL--VLNTPLEDNIMTHGLSSLCSGLVASILGTPADVIKSRIMN 258
Query: 253 QSGEAKRQ---YKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGGALVLVL-YDKIKE 306
Q + + + YK + DC ++ Q EG S ++G + LR T ++V L Y+KI+E
Sbjct: 259 QPRDKQGRGLLYKSSTDCLIQAVQGEGFMSLYKGFLPSWLRMTPWSMVFWLTYEKIRE 316
Score = 52.8 bits (125), Expect = 4e-07
Identities = 40/173 (23%), Positives = 71/173 (41%), Gaps = 13/173 (7%)
Query: 22 KDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFS 81
K ++ G +A + + P + VK+ +Q++ K R++G+ +I E G
Sbjct: 129 KSVIGGMMAGVIGQFLANPTDLVKVQMQMEGKRKLEGKPLRFRGVHHAFAKILAEGGIRG 188
Query: 82 FWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLC 141
W G + N+ R + D K + E L++L SG A
Sbjct: 189 LWAGWVPNIQRAALVNMGDLTTYDTVKHYLVLNTPLEDNIMTHGLSSLCSGLVASILGT- 247
Query: 142 VVYPLDFARTRLGVDIGKGPEERQFKGL-----GDCIMKIAKSDGIAGLYQGF 189
P D ++R I P ++Q +GL DC+++ + +G LY+GF
Sbjct: 248 ---PADVIKSR----IMNQPRDKQGRGLLYKSSTDCLIQAVQGEGFMSLYKGF 293
Score = 37.4 bits (85), Expect = 0.017
Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 6/96 (6%)
Query: 21 GKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFF 80
G L G+ A++ T P + +K + Q KQ YK DCL++ + +GF
Sbjct: 232 GLSSLCSGLVASILGT---PADVIKSRIMNQPRDKQ-GRGLLYKSSTDCLIQAVQGEGFM 287
Query: 81 SFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVN 116
S ++G L + +R P + + +K ++ MSGV+
Sbjct: 288 SLYKGFLPSWLRMTPWSMVFWLTYEKIRE--MSGVS 321
Score = 34.7 bits (78), Expect = 0.11
Identities = 25/107 (23%), Positives = 49/107 (45%), Gaps = 15/107 (14%)
Query: 213 LLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQS-------GEAKRQ---YK 262
LLP ++ P F ++ T + + ++P D + R+ MQ G+ R+ Y+
Sbjct: 10 LLPLTQRWPRASKFLLSGCAATVAELATFPLDLTKTRLQMQGEAALARLGDGARESAPYR 69
Query: 263 GTLDCFVKIYQHEGISSFFRGAFSNVLRG---TGGALVLVLYDKIKE 306
G + + I + EG ++G + R +GG +V Y+ ++E
Sbjct: 70 GMVRTALGIIEEEGFLKLWQGVTPAIYRHVVYSGGR--MVTYEHLRE 114
>gi|58197562 solute carrier family 25, member 30 [Homo sapiens]
Length = 291
Score = 94.4 bits (233), Expect = 1e-19
Identities = 80/300 (26%), Positives = 130/300 (43%), Gaps = 33/300 (11%)
Query: 22 KDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQIS-PEARYKGMVDCLVRIPREQGFF 80
K + GG+A+ ++ PI+ K LQ+Q + E RY+GM+ LVRI RE+G
Sbjct: 7 KPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLK 66
Query: 81 SFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSL 140
+ + G ++R + K+LF+ E N+ G +G S
Sbjct: 67 ALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDET-----LPINVICGILSGVISS 121
Query: 141 CVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYR 200
+ P D + R+ + G+ M I + +G GL++G ++ Q +
Sbjct: 122 TIANPTDVLKIRM-----QAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVV 176
Query: 201 ASYFGAYDTVK------GLLPKPKKTPFLVSFFIAQVVTTC---SGILSYPFDTVRRRMM 251
YD K GL+ T FL SF TC + S P D VR RMM
Sbjct: 177 GVELPVYDITKKHLILSGLMGDTVYTHFLSSF-------TCGLAGALASNPVDVVRTRMM 229
Query: 252 ----MQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLR-GTGGALVLVLYDKIKE 306
++ G Y GTLDC ++ +++EG + ++G + N LR G + V Y+++K+
Sbjct: 230 NQRVLRDGRCS-GYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288
Score = 34.7 bits (78), Expect = 0.11
Identities = 15/48 (31%), Positives = 28/48 (58%)
Query: 63 YKGMVDCLVRIPREQGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQL 110
Y G +DCL++ + +GFF+ ++G N +R P + F ++ K+L
Sbjct: 242 YTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKKL 289
>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 94.0 bits (232), Expect = 2e-19
Identities = 70/279 (25%), Positives = 124/279 (44%), Gaps = 20/279 (7%)
Query: 25 LAGGVAAAVSKTAVAPIERVKLLLQVQASSKQIS-PEARYKGMVDCLVRIPREQGFFSFW 83
+AG V+ V++ ++P + +K+ Q+Q S P A+Y G++ +I +E+G +FW
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 84 RGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVV 143
+G++ I A+ F + +L G + R F + GG A + V
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDA---REFSVHFVCGGLAACMATLTV 136
Query: 144 YPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRASY 203
+P+D RTR E + + L + + +S+G Y+G ++ I Y
Sbjct: 137 HPVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQ 192
Query: 204 FGAYDTVKGLLP-----KPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGEAK 258
F Y ++K L + KK L + S L+YP D ++R+ + E
Sbjct: 193 FSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHA 252
Query: 259 R-------QYKGTLDCFVKIYQHEGISSFFRGAFSNVLR 290
R +YKG +DC ++ Q EG FF+G ++L+
Sbjct: 253 RAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLK 291
Score = 67.8 bits (164), Expect = 1e-11
Identities = 50/200 (25%), Positives = 88/200 (44%), Gaps = 12/200 (6%)
Query: 14 LFDASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRI 73
++DA F + GG+AA ++ V P++ ++ Q K Y + + +
Sbjct: 112 VYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKV------YNTLRHAVGTM 165
Query: 74 PREQGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGG 133
R +G F++G +I FP L F+ K L+ + E + L NL G
Sbjct: 166 YRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKK-NENLQNLLCGS 224
Query: 134 AAGATSLCVVYPLDFARTRL---GVDIGKGP--EERQFKGLGDCIMKIAKSDGIAGLYQG 188
AG S + YPLD + RL G + + + R++KGL DC ++ + +G G ++G
Sbjct: 225 GAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKG 284
Query: 189 FGVSVQGIIVYRASYFGAYD 208
S+ + F +Y+
Sbjct: 285 LSPSLLKAALSTGFMFFSYE 304
>gi|186928860 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 94.0 bits (232), Expect = 2e-19
Identities = 70/279 (25%), Positives = 124/279 (44%), Gaps = 20/279 (7%)
Query: 25 LAGGVAAAVSKTAVAPIERVKLLLQVQASSKQIS-PEARYKGMVDCLVRIPREQGFFSFW 83
+AG V+ V++ ++P + +K+ Q+Q S P A+Y G++ +I +E+G +FW
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 84 RGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVV 143
+G++ I A+ F + +L G + R F + GG A + V
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDA---REFSVHFVCGGLAACMATLTV 136
Query: 144 YPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRASY 203
+P+D RTR E + + L + + +S+G Y+G ++ I Y
Sbjct: 137 HPVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQ 192
Query: 204 FGAYDTVKGLLP-----KPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGEAK 258
F Y ++K L + KK L + S L+YP D ++R+ + E
Sbjct: 193 FSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHA 252
Query: 259 R-------QYKGTLDCFVKIYQHEGISSFFRGAFSNVLR 290
R +YKG +DC ++ Q EG FF+G ++L+
Sbjct: 253 RAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLK 291
Score = 67.8 bits (164), Expect = 1e-11
Identities = 50/200 (25%), Positives = 88/200 (44%), Gaps = 12/200 (6%)
Query: 14 LFDASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRI 73
++DA F + GG+AA ++ V P++ ++ Q K Y + + +
Sbjct: 112 VYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKV------YNTLRHAVGTM 165
Query: 74 PREQGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGG 133
R +G F++G +I FP L F+ K L+ + E + L NL G
Sbjct: 166 YRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKK-NENLQNLLCGS 224
Query: 134 AAGATSLCVVYPLDFARTRL---GVDIGKGP--EERQFKGLGDCIMKIAKSDGIAGLYQG 188
AG S + YPLD + RL G + + + R++KGL DC ++ + +G G ++G
Sbjct: 225 GAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKG 284
Query: 189 FGVSVQGIIVYRASYFGAYD 208
S+ + F +Y+
Sbjct: 285 LSPSLLKAALSTGFMFFSYE 304
>gi|186928858 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 94.0 bits (232), Expect = 2e-19
Identities = 70/279 (25%), Positives = 124/279 (44%), Gaps = 20/279 (7%)
Query: 25 LAGGVAAAVSKTAVAPIERVKLLLQVQASSKQIS-PEARYKGMVDCLVRIPREQGFFSFW 83
+AG V+ V++ ++P + +K+ Q+Q S P A+Y G++ +I +E+G +FW
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 84 RGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVV 143
+G++ I A+ F + +L G + R F + GG A + V
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDA---REFSVHFVCGGLAACMATLTV 136
Query: 144 YPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRASY 203
+P+D RTR E + + L + + +S+G Y+G ++ I Y
Sbjct: 137 HPVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQ 192
Query: 204 FGAYDTVKGLLP-----KPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGEAK 258
F Y ++K L + KK L + S L+YP D ++R+ + E
Sbjct: 193 FSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHA 252
Query: 259 R-------QYKGTLDCFVKIYQHEGISSFFRGAFSNVLR 290
R +YKG +DC ++ Q EG FF+G ++L+
Sbjct: 253 RAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLK 291
Score = 67.8 bits (164), Expect = 1e-11
Identities = 50/200 (25%), Positives = 88/200 (44%), Gaps = 12/200 (6%)
Query: 14 LFDASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRI 73
++DA F + GG+AA ++ V P++ ++ Q K Y + + +
Sbjct: 112 VYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKV------YNTLRHAVGTM 165
Query: 74 PREQGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGG 133
R +G F++G +I FP L F+ K L+ + E + L NL G
Sbjct: 166 YRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKK-NENLQNLLCGS 224
Query: 134 AAGATSLCVVYPLDFARTRL---GVDIGKGP--EERQFKGLGDCIMKIAKSDGIAGLYQG 188
AG S + YPLD + RL G + + + R++KGL DC ++ + +G G ++G
Sbjct: 225 GAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKG 284
Query: 189 FGVSVQGIIVYRASYFGAYD 208
S+ + F +Y+
Sbjct: 285 LSPSLLKAALSTGFMFFSYE 304
>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
sapiens]
Length = 325
Score = 93.2 bits (230), Expect = 3e-19
Identities = 78/292 (26%), Positives = 132/292 (45%), Gaps = 20/292 (6%)
Query: 22 KDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQIS-PEARYKGMVDCLVRIPREQGFF 80
K + GG+A+ V++ P++ K LQVQ S E +Y+GM L RI +E+G
Sbjct: 42 KPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVL 101
Query: 81 SFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSL 140
+ + G ++R + K+LF+ + E L N+ G +G S
Sbjct: 102 ALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDET-----LLINMICGVVSGVISS 156
Query: 141 CVVYPLDFARTRLGVDIGKGPEERQFKG--LGDCIMKIAKSDGIAGLYQGFGVSVQGIIV 198
+ P D + R+ + F+G +G I I + +G GL++G + Q +
Sbjct: 157 TIANPTDVLKIRMQA------QGSLFQGSMIGSFI-DIYQQEGTRGLWRGVVPTAQRAAI 209
Query: 199 YRASYFGAYD-TVKGLLPKPKKTPFLVSFFIAQVVTTCSGIL-SYPFDTVRRRMMMQSGE 256
YD T K L+ +++ F++ +G L S P D VR RMM Q
Sbjct: 210 VVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAI 269
Query: 257 AKRQ--YKGTLDCFVKIYQHEGISSFFRGAFSNVLR-GTGGALVLVLYDKIK 305
YKGT+D +K+++HEG + ++G + N LR G + + Y+++K
Sbjct: 270 VGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 321
Score = 33.5 bits (75), Expect = 0.25
Identities = 15/48 (31%), Positives = 29/48 (60%)
Query: 63 YKGMVDCLVRIPREQGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQL 110
YKG VD ++++ + +GFF+ ++G N +R P + F ++ K+L
Sbjct: 276 YKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRL 323
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.140 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,920,908
Number of Sequences: 37866
Number of extensions: 437256
Number of successful extensions: 1521
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 931
Number of HSP's gapped (non-prelim): 183
length of query: 315
length of database: 18,247,518
effective HSP length: 102
effective length of query: 213
effective length of database: 14,385,186
effective search space: 3064044618
effective search space used: 3064044618
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.