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Search of human proteins with 6005709
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens]
(1103 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens] 2178 0.0
gi|22325356 PALM2-AKAP2 protein isoform 2 [Homo sapiens] 2144 0.0
gi|51873058 A kinase (PRKA) anchor protein 2 isoform 1 [Homo sap... 1773 0.0
gi|211971074 A kinase (PRKA) anchor protein 2 isoform 2 [Homo sa... 1696 0.0
gi|82524851 paralemmin 2 isoform a [Homo sapiens] 326 9e-89
gi|82617626 paralemmin 2 isoform b [Homo sapiens] 252 2e-66
gi|8923243 palmdelphin [Homo sapiens] 120 9e-27
gi|93141031 paralemmin isoform 1 [Homo sapiens] 110 7e-24
gi|93141029 paralemmin isoform 2 [Homo sapiens] 109 1e-23
gi|222537747 hypothetical protein LOC342979 [Homo sapiens] 71 5e-12
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap... 54 8e-07
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa... 54 1e-06
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 52 3e-06
gi|150170670 piccolo isoform 2 [Homo sapiens] 52 3e-06
gi|150378539 piccolo isoform 1 [Homo sapiens] 52 3e-06
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 51 5e-06
gi|29826321 adducin 1 (alpha) isoform b [Homo sapiens] 50 2e-05
gi|110611218 ribosome binding protein 1 [Homo sapiens] 49 3e-05
gi|110611220 ribosome binding protein 1 [Homo sapiens] 49 3e-05
gi|109240550 paraspeckle protein 1 [Homo sapiens] 49 3e-05
gi|221139761 zinc finger protein 853 [Homo sapiens] 48 6e-05
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa... 47 8e-05
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa... 47 8e-05
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens] 47 8e-05
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 47 8e-05
gi|29826319 adducin 1 (alpha) isoform a [Homo sapiens] 47 1e-04
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa... 46 2e-04
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa... 46 2e-04
gi|148746195 trichohyalin [Homo sapiens] 46 2e-04
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 46 2e-04
>gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens]
Length = 1103
Score = 2178 bits (5644), Expect = 0.0
Identities = 1103/1103 (100%), Positives = 1103/1103 (100%)
Query: 1 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA 60
MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA
Sbjct: 1 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA 60
Query: 61 EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK 120
EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK
Sbjct: 61 EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK 120
Query: 121 DFQKGFSSTDGDAVNYISSQLPDLPILCSRTAEPSPGQDGTSRAAGVGWENVLLKEGESA 180
DFQKGFSSTDGDAVNYISSQLPDLPILCSRTAEPSPGQDGTSRAAGVGWENVLLKEGESA
Sbjct: 121 DFQKGFSSTDGDAVNYISSQLPDLPILCSRTAEPSPGQDGTSRAAGVGWENVLLKEGESA 180
Query: 181 SNATETSGPDMTIKKPPQLSEDDIWLKSEGDNYSATLLEPAASSLSPDHKNMEIEVSVAE 240
SNATETSGPDMTIKKPPQLSEDDIWLKSEGDNYSATLLEPAASSLSPDHKNMEIEVSVAE
Sbjct: 181 SNATETSGPDMTIKKPPQLSEDDIWLKSEGDNYSATLLEPAASSLSPDHKNMEIEVSVAE 240
Query: 241 CKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVLEANCCDSAV 300
CKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVLEANCCDSAV
Sbjct: 241 CKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVLEANCCDSAV 300
Query: 301 DGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNSSPDPMAEAE 360
DGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNSSPDPMAEAE
Sbjct: 301 DGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNSSPDPMAEAE 360
Query: 361 RTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKK 420
RTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKK
Sbjct: 361 RTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKK 420
Query: 421 PSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKT 480
PSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKT
Sbjct: 421 PSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKT 480
Query: 481 IEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMI 540
IEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMI
Sbjct: 481 IEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMI 540
Query: 541 DKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLT 600
DKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLT
Sbjct: 541 DKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLT 600
Query: 601 NPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKRGPLSK 660
NPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKRGPLSK
Sbjct: 601 NPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKRGPLSK 660
Query: 661 LWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLE 720
LWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLE
Sbjct: 661 LWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLE 720
Query: 721 TLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGVSKSFSDHGF 780
TLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGVSKSFSDHGF
Sbjct: 721 TLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGVSKSFSDHGF 780
Query: 781 YSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQQGPEATVEE 840
YSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQQGPEATVEE
Sbjct: 781 YSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQQGPEATVEE 840
Query: 841 AEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSGPI 900
AEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSGPI
Sbjct: 841 AEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSGPI 900
Query: 901 NMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAA 960
NMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAA
Sbjct: 901 NMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAA 960
Query: 961 QEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPTTEGPSLQPD 1020
QEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPTTEGPSLQPD
Sbjct: 961 QEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPTTEGPSLQPD 1020
Query: 1021 LAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSYTSKLLSCKVTSEVLEATRVNR 1080
LAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSYTSKLLSCKVTSEVLEATRVNR
Sbjct: 1021 LAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSYTSKLLSCKVTSEVLEATRVNR 1080
Query: 1081 RKSALALRWEAGIYANQEEEDNE 1103
RKSALALRWEAGIYANQEEEDNE
Sbjct: 1081 RKSALALRWEAGIYANQEEEDNE 1103
>gi|22325356 PALM2-AKAP2 protein isoform 2 [Homo sapiens]
Length = 1090
Score = 2144 bits (5555), Expect = 0.0
Identities = 1090/1103 (98%), Positives = 1090/1103 (98%), Gaps = 13/1103 (1%)
Query: 1 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA 60
MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA
Sbjct: 1 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA 60
Query: 61 EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK 120
EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK
Sbjct: 61 EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK 120
Query: 121 DFQKGFSSTDGDAVNYISSQLPDLPILCSRTAEPSPGQDGTSRAAGVGWENVLLKEGESA 180
DFQKGFSSTDGDAVNYISSQLPDLPILCSRTAEPSPGQDGTSRAAGVGWENVLLKEGESA
Sbjct: 121 DFQKGFSSTDGDAVNYISSQLPDLPILCSRTAEPSPGQDGTSRAAGVGWENVLLKEGESA 180
Query: 181 SNATETSGPDMTIKKPPQLSEDDIWLKSEGDNYSATLLEPAASSLSPDHKNMEIEVSVAE 240
SNATETSGPDMTIKKPPQLSEDDIWLKSEGDNYSATLLEPAASSLSPDHKNMEIEVSVAE
Sbjct: 181 SNATETSGPDMTIKKPPQLSEDDIWLKSEGDNYSATLLEPAASSLSPDHKNMEIEVSVAE 240
Query: 241 CKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVLEANCCDSAV 300
CKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVLEANCCDSAV
Sbjct: 241 CKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVLEANCCDSAV 300
Query: 301 DGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNSSPDPMAEAE 360
DGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNSSPDPMAEAE
Sbjct: 301 DGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNSSPDPMAEAE 360
Query: 361 RTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKK 420
RTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKK
Sbjct: 361 RTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKK 420
Query: 421 PSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKT 480
PSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKT
Sbjct: 421 PSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKT 480
Query: 481 IEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMI 540
IEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMI
Sbjct: 481 IEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMI 540
Query: 541 DKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLT 600
DKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLT
Sbjct: 541 DKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLT 600
Query: 601 NPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKRGPLSK 660
NPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKRGPLSK
Sbjct: 601 NPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKRGPLSK 660
Query: 661 LWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLE 720
LWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLE
Sbjct: 661 LWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLE 720
Query: 721 TLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGVSKSFSDHGF 780
TLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGVSKSFSDHGF
Sbjct: 721 TLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGVSKSFSDHGF 780
Query: 781 YSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQQGPEATVEE 840
YSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQQGPEATVEE
Sbjct: 781 YSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQQGPEATVEE 840
Query: 841 AEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSGPI 900
AEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSGPI
Sbjct: 841 AEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSGPI 900
Query: 901 NMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAA 960
NMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAA
Sbjct: 901 NMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAA 960
Query: 961 QEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPTTEGPSLQPD 1020
QEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPTTEGPSLQPD
Sbjct: 961 QEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPTTEGPSLQPD 1020
Query: 1021 LAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSYTSKLLSCKVTSEVLEATRVNR 1080
LAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSS VLEATRVNR
Sbjct: 1021 LAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSS-------------VLEATRVNR 1067
Query: 1081 RKSALALRWEAGIYANQEEEDNE 1103
RKSALALRWEAGIYANQEEEDNE
Sbjct: 1068 RKSALALRWEAGIYANQEEEDNE 1090
>gi|51873058 A kinase (PRKA) anchor protein 2 isoform 1 [Homo sapiens]
Length = 948
Score = 1773 bits (4591), Expect = 0.0
Identities = 904/949 (95%), Positives = 906/949 (95%), Gaps = 22/949 (2%)
Query: 155 SPGQDGTSRAAGVGWENVLLKEGESASNATETSGPDMTIKKPPQLSEDDIWLKSEGDNYS 214
SPG AA W ++ S E KPPQLSEDDIWLKSEGDNYS
Sbjct: 22 SPGPPEREAAAARRWTGAEPQDCAPGSGRPE---------KPPQLSEDDIWLKSEGDNYS 72
Query: 215 ATLLEPAASSLSPDHKNMEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHE 274
ATLLEPAASSLSPDHKNMEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHE
Sbjct: 73 ATLLEPAASSLSPDHKNMEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHE 132
Query: 275 SLDNDVAREIRYLDEVLEANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPT 334
SLDNDVAREIRYLDEVLEANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPT
Sbjct: 133 SLDNDVAREIRYLDEVLEANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPT 192
Query: 335 ERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSS 394
ERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSS
Sbjct: 193 ERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSS 252
Query: 395 RDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERR 454
RDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERR
Sbjct: 253 RDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERR 312
Query: 455 ELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQ 514
ELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQ
Sbjct: 313 ELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQ 372
Query: 515 LQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKG 574
LQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKG
Sbjct: 373 LQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKG 432
Query: 575 QSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAA 634
QSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAA
Sbjct: 433 QSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAA 492
Query: 635 GSQGNTASQGKEGPYSEPSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVN 694
GSQGNTASQGKEGPYSEPSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVN
Sbjct: 493 GSQGNTASQGKEGPYSEPSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVN 552
Query: 695 VSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSL 754
VSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSL
Sbjct: 553 VSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSL 612
Query: 755 PQTPQTDNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIA 814
PQTPQTDNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIA
Sbjct: 613 PQTPQTDNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIA 672
Query: 815 EQVDKAVSKTSRDGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKI 874
EQVDKAVSKTSRDGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKI
Sbjct: 673 EQVDKAVSKTSRDGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKI 732
Query: 875 LPAEDRALRERGPPQPLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESD 934
LPAEDRALRERGPPQPLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESD
Sbjct: 733 LPAEDRALRERGPPQPLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESD 792
Query: 935 VMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCY 994
VMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCY
Sbjct: 793 VMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCY 852
Query: 995 KTAPGKIEKVKPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERM 1054
KTAPGKIEKVKPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERM
Sbjct: 853 KTAPGKIEKVKPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERM 912
Query: 1055 DDSSYTSKLLSCKVTSEVLEATRVNRRKSALALRWEAGIYANQEEEDNE 1103
DDSS VLEATRVNRRKSALALRWEAGIYANQEEEDNE
Sbjct: 913 DDSS-------------VLEATRVNRRKSALALRWEAGIYANQEEEDNE 948
>gi|211971074 A kinase (PRKA) anchor protein 2 isoform 2 [Homo
sapiens]
Length = 859
Score = 1696 bits (4392), Expect = 0.0
Identities = 859/872 (98%), Positives = 859/872 (98%), Gaps = 13/872 (1%)
Query: 232 MEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVL 291
MEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVL
Sbjct: 1 MEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVL 60
Query: 292 EANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNS 351
EANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNS
Sbjct: 61 EANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNS 120
Query: 352 SPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFE 411
SPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFE
Sbjct: 121 SPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFE 180
Query: 412 LRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAK 471
LRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAK
Sbjct: 181 LRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAK 240
Query: 472 WWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPA 531
WWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPA
Sbjct: 241 WWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPA 300
Query: 532 SSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLG 591
SSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLG
Sbjct: 301 SSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLG 360
Query: 592 SVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSE 651
SVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSE
Sbjct: 361 SVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSE 420
Query: 652 PSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSV 711
PSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSV
Sbjct: 421 PSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSV 480
Query: 712 RSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGV 771
RSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGV
Sbjct: 481 RSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGV 540
Query: 772 SKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQ 831
SKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQ
Sbjct: 541 SKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQ 600
Query: 832 QGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPL 891
QGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPL
Sbjct: 601 QGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPL 660
Query: 892 PAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLS 951
PAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLS
Sbjct: 661 PAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLS 720
Query: 952 MIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPT 1011
MIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPT
Sbjct: 721 MIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPT 780
Query: 1012 TEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSYTSKLLSCKVTSE 1071
TEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSS
Sbjct: 781 TEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSS------------- 827
Query: 1072 VLEATRVNRRKSALALRWEAGIYANQEEEDNE 1103
VLEATRVNRRKSALALRWEAGIYANQEEEDNE
Sbjct: 828 VLEATRVNRRKSALALRWEAGIYANQEEEDNE 859
>gi|82524851 paralemmin 2 isoform a [Homo sapiens]
Length = 413
Score = 326 bits (835), Expect = 9e-89
Identities = 174/206 (84%), Positives = 185/206 (89%), Gaps = 4/206 (1%)
Query: 1 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA 60
MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA
Sbjct: 3 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA 62
Query: 61 EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK 120
EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK
Sbjct: 63 EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK 122
Query: 121 DFQKGFSSTDGDAVNYISSQLPDLPILCSRTAEPSPGQDGTSRAAGVGWENVLLKE---- 176
DFQKGFSSTDGDAVNYISSQLPDLPILCSRTAEPSPGQDGTSRAA V + +++
Sbjct: 123 DFQKGFSSTDGDAVNYISSQLPDLPILCSRTAEPSPGQDGTSRAAAVYAMEINVEKDKQT 182
Query: 177 GESASNATETSGPDMTIKKPPQLSED 202
GE+ +T T GP+ +K ++ +D
Sbjct: 183 GETKILSTSTIGPEGVHQKGVKVYDD 208
>gi|82617626 paralemmin 2 isoform b [Homo sapiens]
Length = 379
Score = 252 bits (643), Expect = 2e-66
Identities = 173/353 (49%), Positives = 203/353 (57%), Gaps = 20/353 (5%)
Query: 1 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA 60
MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA
Sbjct: 3 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA 62
Query: 61 EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK 120
EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK
Sbjct: 63 EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK 122
Query: 121 DFQKGFSSTDGDA----VNY-ISSQLPDLPILCSRTAEPSPGQDGTSRAAGVGWENVL-L 174
DFQKGFSSTDG +N Q + IL + T P + G + V +
Sbjct: 123 DFQKGFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVYEV 182
Query: 175 KEG----ESASNATETSGPDMTIKKPPQLSEDDIWLKSEGDNYSATLLEPAASSLSPDHK 230
+ G E+ + T + I+K Q S + +L P L + K
Sbjct: 183 RSGGTVVENGVHKLSTKDVEELIQKAGQSSLGGGHVSERTVIADGSLSHPKEHMLCKEAK 242
Query: 231 NMEIEVSVAECKS-VPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDE 289
+ S + S PG + P A P + + D + +++ DE
Sbjct: 243 LEMVHKSRKDHSSGNPGQQAQAPSAAGPEANLDQPVTMIFMGYQNIEDEEETKKVLGYDE 302
Query: 290 VLEANCC-------DSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTE 335
++A S + T S+ + A LV G PV + T+P E
Sbjct: 303 TIKAELVLIDEDDEKSLREKTVTDVSTIDGNAAELVSG--RPVSDTTEPSSPE 353
>gi|8923243 palmdelphin [Homo sapiens]
Length = 551
Score = 120 bits (300), Expect = 9e-27
Identities = 68/149 (45%), Positives = 97/149 (65%), Gaps = 6/149 (4%)
Query: 1 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA 60
M EAEL K RLQAI +KRK Q EI KR +++E L QH K K LREKWLL GI +G
Sbjct: 1 MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSG-- 58
Query: 61 EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK 120
+E+E ++Q+++D+ +++ LE +I RLE+EIQ LE E QIS KE+ IL+KLK E++ +
Sbjct: 59 KEQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTE 118
Query: 121 DFQKGF----SSTDGDAVNYISSQLPDLP 145
D + +++ I + +PDLP
Sbjct: 119 DIIRSVKVEREERAEESIEDIYANIPDLP 147
>gi|93141031 paralemmin isoform 1 [Homo sapiens]
Length = 387
Score = 110 bits (275), Expect = 7e-24
Identities = 83/258 (32%), Positives = 132/258 (51%), Gaps = 16/258 (6%)
Query: 2 AEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAE 61
AE +ERLQAIAEKRKRQ EIE KR+QL+++ LQH KSK LRE+WLL+G P+ +E
Sbjct: 6 AETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASE 65
Query: 62 EEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLE-SEESQISAKEQI-----ILEKLKET 115
+E RRQ ++DE + + LED++ RLE+EI+ LE + + +AKE +
Sbjct: 66 GDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRAPAPSP 125
Query: 116 EKSFKDFQKGFSSTDGDAVNYISSQLPDLPILCSRTAEPSPGQDGTSRAAGVGWENVLLK 175
K + + +S ++ + P+ RT + SP +AA E + K
Sbjct: 126 AKEERKTEVVMNSQQTPVGTPKDKRVSNTPL---RTVDGSP----MMKAAMYSVEITVEK 178
Query: 176 E---GESASNATETSGPDMTIKKPPQLSEDDIWLKSEGDNYSATLLEPAASSLSPDHKNM 232
+ GE+ ++ T P + ++ ED+ + D + + P +SS + +
Sbjct: 179 DKVTGETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAVDGTAENGIHPLSSSEVDELIHK 238
Query: 233 EIEVSVAECKSVPGITST 250
EV+++E S G T
Sbjct: 239 ADEVTLSEAGSTAGAAET 256
>gi|93141029 paralemmin isoform 2 [Homo sapiens]
Length = 343
Score = 109 bits (273), Expect = 1e-23
Identities = 56/105 (53%), Positives = 77/105 (73%), Gaps = 1/105 (0%)
Query: 2 AEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAE 61
AE +ERLQAIAEKRKRQ EIE KR+QL+++ LQH KSK LRE+WLL+G P+ +E
Sbjct: 6 AETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASE 65
Query: 62 EEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLE-SEESQISAKE 105
+E RRQ ++DE + + LED++ RLE+EI+ LE + + +AKE
Sbjct: 66 GDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKE 110
>gi|222537747 hypothetical protein LOC342979 [Homo sapiens]
Length = 673
Score = 71.2 bits (173), Expect = 5e-12
Identities = 38/100 (38%), Positives = 66/100 (66%), Gaps = 4/100 (4%)
Query: 1 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPA--G 58
MAE+ L+++RL+ IAEKR+ Q EI R++++E+ L ++ K K LRE+WL+ G A
Sbjct: 1 MAESSLYRQRLEVIAEKRRLQEEIRAARREVEEEKLRVERLKRKSLRERWLMDGAAAVPE 60
Query: 59 TAEEEEARRRQSEED--EFRVKQLEDNIQRLEQEIQTLES 96
+E+ ++ QS E + R++ LED++ L+ ++Q L+S
Sbjct: 61 PSEDPTSKDPQSPEGQAQARIRNLEDSLFTLQSQLQLLQS 100
>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo
sapiens]
Length = 1360
Score = 53.9 bits (128), Expect = 8e-07
Identities = 113/506 (22%), Positives = 202/506 (39%), Gaps = 48/506 (9%)
Query: 3 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEE 62
E E HK +L +AE++KR E + +R++L+EQ + + + RE+ +
Sbjct: 379 ENEEHKRQL--LAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQ---RRHYEEQMRR 433
Query: 63 EEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKDF 122
EE RRR E E+ +QLE+ ++LE Q L E++ + ++ LE+ ++ E+ +
Sbjct: 434 EEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQL 493
Query: 123 QKGFSSTDGDAVNYISSQLPDLPILCSRTAEPSP---GQDGTSRAAGVGWENVLLKEGES 179
++ + D + + Q + R E P ++G S + W KE E
Sbjct: 494 KQ-----ERDYLVSLQHQRQE-----QRPVEKKPLYHYKEGMSPSEKPAW----AKEVEE 539
Query: 180 ASNATETSGPDMTIKKPPQLSEDDIWLKSEGDNYSATLLEPAASSLSPDHKNMEIEVSVA 239
S S P M K ++S+ ++ +SE ++S + ++PA + + +I VA
Sbjct: 540 RSRLNRQSSPAMPHKVANRISDPNLPPRSE--SFSISGVQPARTPPMLRPVDPQIPHLVA 597
Query: 240 ECKSVPGITSTPHPMDHPSAFYSPPHNGL-LTDHHESL---DNDVAREIRYLDEVLEANC 295
P +T++ + P+ S L +T H + ++D E L +E
Sbjct: 598 VKSQGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFD 657
Query: 296 CDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNSS--- 352
S + P +SP + P R I SN
Sbjct: 658 RSSWL----RQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRR 713
Query: 353 PDPMAEA--ERTNGHSPSQPRDALGDSLQVPVS-PSSTTSSRCSSRDGEFTLTTLKKEAK 409
+P+ E+ +RT+ S S S P S PSS S+ S+ G T ++ +K
Sbjct: 714 TEPILESPLQRTSSGSSS--------SSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSK 765
Query: 410 FELRAF--HEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPG 467
E HE K D + K E++ L KE REL + +
Sbjct: 766 SEGSPVLPHEPAKVKPEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKK 825
Query: 468 IAAKWWNPPQEKTIEEQLDEEHLESH 493
+ + + ++ EE+ ++ E+H
Sbjct: 826 VTDYSSSSEESESSEEEEEDGESETH 851
Score = 46.2 bits (108), Expect = 2e-04
Identities = 57/277 (20%), Positives = 113/277 (40%), Gaps = 35/277 (12%)
Query: 326 HEATQPEPTERTASRQAPPHIELSNSSPDPMAEAE-RTNGHSPSQPRDALGDSLQVPVSP 384
H + +P ER Q HI+ + E E +G + + G+ + P
Sbjct: 286 HPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLP 345
Query: 385 SSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSE 444
+T R +F L + + E A + + E++EH+++ R+ R
Sbjct: 346 GESTLRR------DFLRLQLANKERSE--ALRRQQLEQQQRENEEHKRQLLAERQKR--- 394
Query: 445 EMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKE--R 502
+E +KE+R + Q + EK + +Q + E +++ R+E R
Sbjct: 395 --IEEQKEQRRRLEEQQRR--------------EKELRKQQEREQRRHYEEQMRREEERR 438
Query: 503 RAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQ 562
RA+ EQ +++QL+++Q+Q HE+A +++ ++ + EQ ++Q +
Sbjct: 439 RAEHEQEYIRRQLEEEQRQLE---ILQQQLLHEQALLLEYKRKQL-EEQRQAERLQRQLK 494
Query: 563 LMENSRQAVAKGQSTPRLFSIKPFYR-PLGSVNSDKP 598
+ ++ + R KP Y G S+KP
Sbjct: 495 QERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKP 531
>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
sapiens]
Length = 1352
Score = 53.5 bits (127), Expect = 1e-06
Identities = 115/506 (22%), Positives = 209/506 (41%), Gaps = 56/506 (11%)
Query: 3 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEE 62
E E HK +L +AE++KR E + +R++L+EQ + + + RE+ +
Sbjct: 379 ENEEHKRQL--LAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQ---RRHYEEQMRR 433
Query: 63 EEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKDF 122
EE RRR E E+ +QLE+ ++LE Q L E++ + ++ LE+ ++ E+ +
Sbjct: 434 EEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQL 493
Query: 123 QKGFSSTDGDAVNYISSQLPDLPILCSRTAEPSP---GQDGTSRAAGVGWENVLLKEGES 179
++ + D + + Q + R E P ++G S + W KE E
Sbjct: 494 KQ-----ERDYLVSLQHQRQE-----QRPVEKKPLYHYKEGMSPSEKPAW----AKEVEE 539
Query: 180 ASNATETSGPDMTIKKPPQLSEDDIWLKSEGDNYSATLLEPAASSLSPDHKNMEIEVSVA 239
S S P M K ++S+ ++ +SE ++S + ++PA + + +I VA
Sbjct: 540 RSRLNRQSSPAMPHKVANRISDPNLPPRSE--SFSISGVQPARTPPMLRPVDPQIPHLVA 597
Query: 240 ECKSVPGITSTPHPMDHPSAFYSPPHNGL-LTDHHESL---DNDVAREIRYLDEVLEANC 295
P +T++ + P+ S L +T H + ++D E L +E
Sbjct: 598 VKSQGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFD 657
Query: 296 CDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNSS--- 352
S + P +SP + P R I SN
Sbjct: 658 RSSWL----RQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRR 713
Query: 353 PDPMAEA--ERTNGHSPSQPRDALGDSLQVPVS-PSSTTSSRCSSRDGEFTLTTLKKEAK 409
+P+ E+ +RT+ S S S P S PSS S+ S+ G T ++ +K
Sbjct: 714 TEPILESPLQRTSSGSSS--------SSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSK 765
Query: 410 FELRAF--HEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPG 467
E HE P+K+ + E+ + R RP+ ++ L KE REL + +
Sbjct: 766 SEGSPVLPHE---PAKV----KPEESRDITRPSRPA-DLTALAKELRELRIEETNRPMKK 817
Query: 468 IAAKWWNPPQEKTIEEQLDEEHLESH 493
+ + + ++ EE+ ++ E+H
Sbjct: 818 VTDYSSSSEESESSEEEEEDGESETH 843
Score = 46.2 bits (108), Expect = 2e-04
Identities = 57/277 (20%), Positives = 113/277 (40%), Gaps = 35/277 (12%)
Query: 326 HEATQPEPTERTASRQAPPHIELSNSSPDPMAEAE-RTNGHSPSQPRDALGDSLQVPVSP 384
H + +P ER Q HI+ + E E +G + + G+ + P
Sbjct: 286 HPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLP 345
Query: 385 SSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSE 444
+T R +F L + + E A + + E++EH+++ R+ R
Sbjct: 346 GESTLRR------DFLRLQLANKERSE--ALRRQQLEQQQRENEEHKRQLLAERQKR--- 394
Query: 445 EMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKE--R 502
+E +KE+R + Q + EK + +Q + E +++ R+E R
Sbjct: 395 --IEEQKEQRRRLEEQQRR--------------EKELRKQQEREQRRHYEEQMRREEERR 438
Query: 503 RAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQ 562
RA+ EQ +++QL+++Q+Q HE+A +++ ++ + EQ ++Q +
Sbjct: 439 RAEHEQEYIRRQLEEEQRQLE---ILQQQLLHEQALLLEYKRKQL-EEQRQAERLQRQLK 494
Query: 563 LMENSRQAVAKGQSTPRLFSIKPFYR-PLGSVNSDKP 598
+ ++ + R KP Y G S+KP
Sbjct: 495 QERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKP 531
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 52.0 bits (123), Expect = 3e-06
Identities = 57/235 (24%), Positives = 93/235 (39%), Gaps = 41/235 (17%)
Query: 322 SPPVHEATQPEPTERTASRQAPPHI-ELSNSSP----DPMAEAERTNGHSPSQP-RDALG 375
S P + +PEP + S +AP H+ + P P+ N P P +D
Sbjct: 1122 SEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQK 1181
Query: 376 DSLQVPVSPSSTTSSRCSSRDGEFTL---TTLKKEAKFELRAFHEDKKPSKLFEDDEHEK 432
+ PV+P + TT AK +F + ++ ++ E +E EK
Sbjct: 1182 QEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAR--EKEEREK 1239
Query: 433 EQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLES 492
++ E E EKER +++ + + DE+ LE
Sbjct: 1240 ------ALKAQAEHAEKEKERL----------------------RQERMRSREDEDALEQ 1271
Query: 493 HKKYKERKERRAQQEQLLLQKQLQQQQQQPP--SQLCTAPASSHERASMIDKAKE 545
++ E RR +Q+Q Q+Q QQQQQQ + T A S + SM+D+ +E
Sbjct: 1272 ARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRE 1326
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 52.0 bits (123), Expect = 3e-06
Identities = 139/696 (19%), Positives = 272/696 (39%), Gaps = 116/696 (16%)
Query: 63 EEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK-D 121
+E ++++ E +Q +D +++ Q+L SE +I+ E+ I E +E + +FK D
Sbjct: 1429 DEKSEKKTQPHEVSPEQPKD-----QEKTQSL-SETLEITISEEEIKESQEERKDTFKKD 1482
Query: 122 FQKGFSSTD-----GDAVNYISSQL-PDLPILCSRTAEPSPGQDGTSRAAGVGWENVLLK 175
Q+ S+ + V+ I+++ P + S +E SP R + + K
Sbjct: 1483 SQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYK 1542
Query: 176 EGESASNATETSGPDMTIKKPPQLSEDDIWLKSEGDNYSATLLEPAASSLSPDHKNMEIE 235
+ +S + E D K+ ++S D+ SE D + L+ +SS K
Sbjct: 1543 QEDSQGSGEEE---DFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKE---- 1595
Query: 236 VSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVLEANC 295
E K IT+ H L S+D D R + DE EA
Sbjct: 1596 ----ETKGKGKITAGKH-------------RRLTRKSSTSIDEDAGRRHSWHDEDDEA-- 1636
Query: 296 CDSAVDGTYNGTSSPEPGAVVLVGG----------LSPPVHEATQPEPTERTASR--QAP 343
D + + Y T S E +V+ GG L+ + + E +++ S
Sbjct: 1637 FDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEE 1696
Query: 344 PHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTT 403
P +E+ + + P +R+ G S S SP+S +S D + + +
Sbjct: 1697 PELEMESLTDSP---EDRSRGEGSSSLH---ASSFTPGTSPTSVSSL---DEDSDSSPSH 1747
Query: 404 LKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVK 463
K E+K + +A H P +D E+E+ +R EE+L+ ++++RE
Sbjct: 1748 KKGESKQQRKARHRPHGPLLPTIEDSSEEEE-----LREEEELLKEQEKQRE-------- 1794
Query: 464 KNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPP 523
IE+Q + S K K++ E RAQ+ +++ + PP
Sbjct: 1795 -----------------IEQQ--QRKSSSKKSKKDKDELRAQRR--------RERPKTPP 1827
Query: 524 SQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSI 583
S L S E AS ++ ++ E++ S+ + +E+ + S ++ +
Sbjct: 1828 SNL-----SPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEGFE--ISPEKIIEV 1880
Query: 584 KPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQ 643
+ Y+ +V+ L +P E S + ++ + + A++
Sbjct: 1881 QKVYKLPTAVS----LYSPTDEQSIMQKEGSQKALKSAEEMYEEMMHKTHKYKAFPAANE 1936
Query: 644 GKEGPYSEPSKRGPLSKLW-----AEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLT 698
E EP G L + + ED S L +++++G + Q R + L+
Sbjct: 1937 RDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEENGFMQQKGREQKIRLS 1996
Query: 699 QEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDS 734
++ + + +++ ++ LE+L + ++I S
Sbjct: 1997 EQIYEDPMQKITDLQKEFYELESLHSVVPQEDIVSS 2032
Score = 43.9 bits (102), Expect = 8e-04
Identities = 202/1025 (19%), Positives = 365/1025 (35%), Gaps = 177/1025 (17%)
Query: 157 GQDGTSRAAGVGWENVLLKEGESASNATETSGPDMTIKKPPQLSEDDIWLKSEGDNYSAT 216
GQ G +G G +K+ + S + GP + + P I +K E +A
Sbjct: 950 GQPGPHSQSGPG---APMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAE 1006
Query: 217 LLEPAASSLSPDHKNMEIEVSVAECKSVPGITSTPHPMDHPSAF---------------- 260
LEP A +P K E E K +T+ P P+
Sbjct: 1007 KLEPKAEQ-APTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTE 1065
Query: 261 -----YSPPHNGLLTDHHESLDNDVA-REIRYLDEVLEANCCDSAVDGTYNGTSSPEPGA 314
PP+ T+ + N +L E+ E C + +G + G
Sbjct: 1066 LNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISG----QLGD 1121
Query: 315 VVLVGGLSPPVHEATQPEPTERTASRQA-PPHIEL-SNSSPDPMAEAERTNGHSPSQPRD 372
+ + + P PTE ++ + A PP ++L + EAE+ +
Sbjct: 1122 IRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKV-------ILE 1174
Query: 373 ALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEK 432
+ ++L + P T+ + + E L K A E + E+KK E E+
Sbjct: 1175 KVKETLSMEKIPPMVTTDQ---KQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEE 1231
Query: 433 EQYCIRKVRPSEEMLEL---------EKERRELIRSQ---AVKKNPGIAA----KWWNPP 476
++ + + +P+ E +L E+++ +L++SQ A +K G A + P
Sbjct: 1232 KKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQP 1291
Query: 477 QEKT------IEEQLDEEHLESHKKYKERKER--RAQQEQLLLQKQLQQ----------- 517
Q K + L +E ++ K KE+ + A+ +Q+ K+ +
Sbjct: 1292 QTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSS 1351
Query: 518 QQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQA----VAK 573
QQ + P L SS +S + + I T++ D K+ + S + +AK
Sbjct: 1352 QQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAK 1411
Query: 574 GQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSA 633
+ST L ++ L S+K T P S P + K Q LE +
Sbjct: 1412 LESTV-LSILEAQASTLADEKSEKK-TQPHEVSPEQPKDQE-----KTQSLSETLEITIS 1464
Query: 634 AGSQGNTASQGKEGPYSEPSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSV 693
+ + K+ + + P SK E EF + + + +++ S S
Sbjct: 1465 EEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDD----ITTRREPYDSVEESSESE 1520
Query: 694 NVSLTQEEL-----DSGLDELSVR-SQDTTVLETLSNDFSMDNISDSGASNETTNALQEN 747
N + Q + S DE SQ + E ++ +D AS + N
Sbjct: 1521 NSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRN 1580
Query: 748 SLADFSLPQTPQTDNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQN 807
L + S + ++ E +G+G + SST ++ AG ++
Sbjct: 1581 QLKEIS--SSTESQKKEETKGKGKITAGKHRRLTRKSST---------SIDEDAGR--RH 1627
Query: 808 AIQQAIAEQVDKAVSKTSRDGAEQQGPEATVEEA-----------------EAAAFGSEK 850
+ E D++ R+ Q+ E V + +A S+K
Sbjct: 1628 SWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQK 1687
Query: 851 PQSMF--EPPQV------SSPVQEKR----------DVLPKILPAEDRALRERGPPQPLP 892
S++ E P++ SP R P P +L E P
Sbjct: 1688 KTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSH 1747
Query: 893 AVQPSGPINMEETRPEGSY---FSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRT 949
S RP G SE ELR LL QE + + +S +++
Sbjct: 1748 KKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKS 1807
Query: 950 LSMIEEEIRAAQERE------------------EELKRQRQVLQSTQSPRTKNAPSLPS- 990
++E+RA + RE EEL++ ++ + +S ++ +PS+ S
Sbjct: 1808 -KKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESD 1866
Query: 991 RTCYKTAPGKIEKV----KPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQTLMED--YE 1044
++ +P KI +V K P + + P+ + + +E G+Q+ + + E+ ++
Sbjct: 1867 PEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKE--GSQKALKSAEEMYEEMMHK 1924
Query: 1045 THKSK 1049
THK K
Sbjct: 1925 THKYK 1929
Score = 32.0 bits (71), Expect = 3.3
Identities = 55/270 (20%), Positives = 106/270 (39%), Gaps = 47/270 (17%)
Query: 725 DFSMDNISDSG---ASNETTNALQENSLADFSLPQTPQT------DNPSEGRGEGVSKSF 775
+ M++++DS + E +++L +S + P + + +PS +GE +
Sbjct: 1698 ELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRK 1757
Query: 776 SDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQQGPE 835
+ H + P + ++ L + LL + Q+ I +Q K+ SK S+ ++ +
Sbjct: 1758 ARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQ 1817
Query: 836 ATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQ 895
E + P S P + +SP +E R AE L + P++
Sbjct: 1818 RRRERPKT-------PPSNLSPIEDASPTEELRQA------AEMEELHRSSCSEYSPSI- 1863
Query: 896 PSGPINMEETRPEGSYFS-----KYSEAAELRSTASLLA-TQESDVMVGPFKLRSRKQRT 949
E+ PEG S + + +L + SL + T E +M ++ K
Sbjct: 1864 --------ESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAE 1915
Query: 950 LSMIEEEIR---------AAQEREEELKRQ 970
M EE + AA ER+E +++
Sbjct: 1916 -EMYEEMMHKTHKYKAFPAANERDEVFEKE 1944
Score = 30.8 bits (68), Expect = 7.4
Identities = 29/122 (23%), Positives = 60/122 (49%), Gaps = 24/122 (19%)
Query: 417 EDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPP 476
EDK+ +L + E+E + K++ ELE ER+E+ R +
Sbjct: 3207 EDKQQQQL----DLERELLELEKIKQQRFAEELEWERQEIQRFRE--------------- 3247
Query: 477 QEKT-IEEQLDE-EHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSH 534
QEK ++++L+E + ++ H +++ +ER+AQ +++++ QQQ Q+ H
Sbjct: 3248 QEKIMVQKKLEELQSMKQHLLFQQEEERQAQ---FMMRQETLAQQQLQLEQIQQLQQQLH 3304
Query: 535 ER 536
++
Sbjct: 3305 QQ 3306
Score = 30.4 bits (67), Expect = 9.6
Identities = 63/309 (20%), Positives = 111/309 (35%), Gaps = 50/309 (16%)
Query: 756 QTPQTDNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLEYQA-------------- 801
Q+ + +P G+SKS + F S G SP E ++
Sbjct: 95 QSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMP 154
Query: 802 GLLVQNAIQQAIAEQVDKAVSKTSRDGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVS 861
G L + A++ V+K + + E T ++ + KP+ + +PP
Sbjct: 155 GFLSEVNALSAVSSVVNK-FNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQ 213
Query: 862 SPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSG----------PINMEETRPEGSY 911
P + +PK L++ G P+ + + QP PI P+ +
Sbjct: 214 QPPKP----IPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDH 269
Query: 912 FSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQR 971
L+ AS T+++D++ G S + I++ ++ +
Sbjct: 270 AK-----LPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKS 324
Query: 972 QVLQSTQSPRTKNAPSLPSRTCYKTA--PGKIEKVKPPPSP--TTEGPS--LQPDLAPEE 1025
Q P P+ PS A PG VKPP P TT+ P+ L P P +
Sbjct: 325 Q-------PGPAKPPAQPSGLTKPLAQQPGT---VKPPVQPPGTTKPPAQPLGPAKPPAQ 374
Query: 1026 AAGTQRPKN 1034
G+++P +
Sbjct: 375 QTGSEKPSS 383
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 52.0 bits (123), Expect = 3e-06
Identities = 139/696 (19%), Positives = 272/696 (39%), Gaps = 116/696 (16%)
Query: 63 EEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK-D 121
+E ++++ E +Q +D +++ Q+L SE +I+ E+ I E +E + +FK D
Sbjct: 1429 DEKSEKKTQPHEVSPEQPKD-----QEKTQSL-SETLEITISEEEIKESQEERKDTFKKD 1482
Query: 122 FQKGFSSTD-----GDAVNYISSQL-PDLPILCSRTAEPSPGQDGTSRAAGVGWENVLLK 175
Q+ S+ + V+ I+++ P + S +E SP R + + K
Sbjct: 1483 SQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYK 1542
Query: 176 EGESASNATETSGPDMTIKKPPQLSEDDIWLKSEGDNYSATLLEPAASSLSPDHKNMEIE 235
+ +S + E D K+ ++S D+ SE D + L+ +SS K
Sbjct: 1543 QEDSQGSGEEE---DFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKE---- 1595
Query: 236 VSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVLEANC 295
E K IT+ H L S+D D R + DE EA
Sbjct: 1596 ----ETKGKGKITAGKH-------------RRLTRKSSTSIDEDAGRRHSWHDEDDEA-- 1636
Query: 296 CDSAVDGTYNGTSSPEPGAVVLVGG----------LSPPVHEATQPEPTERTASR--QAP 343
D + + Y T S E +V+ GG L+ + + E +++ S
Sbjct: 1637 FDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEE 1696
Query: 344 PHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTT 403
P +E+ + + P +R+ G S S SP+S +S D + + +
Sbjct: 1697 PELEMESLTDSP---EDRSRGEGSSSLH---ASSFTPGTSPTSVSSL---DEDSDSSPSH 1747
Query: 404 LKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVK 463
K E+K + +A H P +D E+E+ +R EE+L+ ++++RE
Sbjct: 1748 KKGESKQQRKARHRPHGPLLPTIEDSSEEEE-----LREEEELLKEQEKQRE-------- 1794
Query: 464 KNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPP 523
IE+Q + S K K++ E RAQ+ +++ + PP
Sbjct: 1795 -----------------IEQQ--QRKSSSKKSKKDKDELRAQRR--------RERPKTPP 1827
Query: 524 SQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSI 583
S L S E AS ++ ++ E++ S+ + +E+ + S ++ +
Sbjct: 1828 SNL-----SPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEGFE--ISPEKIIEV 1880
Query: 584 KPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQ 643
+ Y+ +V+ L +P E S + ++ + + A++
Sbjct: 1881 QKVYKLPTAVS----LYSPTDEQSIMQKEGSQKALKSAEEMYEEMMHKTHKYKAFPAANE 1936
Query: 644 GKEGPYSEPSKRGPLSKLW-----AEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLT 698
E EP G L + + ED S L +++++G + Q R + L+
Sbjct: 1937 RDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEENGFMQQKGREQKIRLS 1996
Query: 699 QEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDS 734
++ + + +++ ++ LE+L + ++I S
Sbjct: 1997 EQIYEDPMQKITDLQKEFYELESLHSVVPQEDIVSS 2032
Score = 43.9 bits (102), Expect = 8e-04
Identities = 202/1025 (19%), Positives = 365/1025 (35%), Gaps = 177/1025 (17%)
Query: 157 GQDGTSRAAGVGWENVLLKEGESASNATETSGPDMTIKKPPQLSEDDIWLKSEGDNYSAT 216
GQ G +G G +K+ + S + GP + + P I +K E +A
Sbjct: 950 GQPGPHSQSGPG---APMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAE 1006
Query: 217 LLEPAASSLSPDHKNMEIEVSVAECKSVPGITSTPHPMDHPSAF---------------- 260
LEP A +P K E E K +T+ P P+
Sbjct: 1007 KLEPKAEQ-APTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTE 1065
Query: 261 -----YSPPHNGLLTDHHESLDNDVA-REIRYLDEVLEANCCDSAVDGTYNGTSSPEPGA 314
PP+ T+ + N +L E+ E C + +G + G
Sbjct: 1066 LNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISG----QLGD 1121
Query: 315 VVLVGGLSPPVHEATQPEPTERTASRQA-PPHIEL-SNSSPDPMAEAERTNGHSPSQPRD 372
+ + + P PTE ++ + A PP ++L + EAE+ +
Sbjct: 1122 IRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKV-------ILE 1174
Query: 373 ALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEK 432
+ ++L + P T+ + + E L K A E + E+KK E E+
Sbjct: 1175 KVKETLSMEKIPPMVTTDQ---KQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEE 1231
Query: 433 EQYCIRKVRPSEEMLEL---------EKERRELIRSQ---AVKKNPGIAA----KWWNPP 476
++ + + +P+ E +L E+++ +L++SQ A +K G A + P
Sbjct: 1232 KKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQP 1291
Query: 477 QEKT------IEEQLDEEHLESHKKYKERKER--RAQQEQLLLQKQLQQ----------- 517
Q K + L +E ++ K KE+ + A+ +Q+ K+ +
Sbjct: 1292 QTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSS 1351
Query: 518 QQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQA----VAK 573
QQ + P L SS +S + + I T++ D K+ + S + +AK
Sbjct: 1352 QQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAK 1411
Query: 574 GQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSA 633
+ST L ++ L S+K T P S P + K Q LE +
Sbjct: 1412 LESTV-LSILEAQASTLADEKSEKK-TQPHEVSPEQPKDQE-----KTQSLSETLEITIS 1464
Query: 634 AGSQGNTASQGKEGPYSEPSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSV 693
+ + K+ + + P SK E EF + + + +++ S S
Sbjct: 1465 EEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDD----ITTRREPYDSVEESSESE 1520
Query: 694 NVSLTQEEL-----DSGLDELSVR-SQDTTVLETLSNDFSMDNISDSGASNETTNALQEN 747
N + Q + S DE SQ + E ++ +D AS + N
Sbjct: 1521 NSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRN 1580
Query: 748 SLADFSLPQTPQTDNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQN 807
L + S + ++ E +G+G + SST ++ AG ++
Sbjct: 1581 QLKEIS--SSTESQKKEETKGKGKITAGKHRRLTRKSST---------SIDEDAGR--RH 1627
Query: 808 AIQQAIAEQVDKAVSKTSRDGAEQQGPEATVEEA-----------------EAAAFGSEK 850
+ E D++ R+ Q+ E V + +A S+K
Sbjct: 1628 SWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQK 1687
Query: 851 PQSMF--EPPQV------SSPVQEKR----------DVLPKILPAEDRALRERGPPQPLP 892
S++ E P++ SP R P P +L E P
Sbjct: 1688 KTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSH 1747
Query: 893 AVQPSGPINMEETRPEGSY---FSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRT 949
S RP G SE ELR LL QE + + +S +++
Sbjct: 1748 KKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKS 1807
Query: 950 LSMIEEEIRAAQERE------------------EELKRQRQVLQSTQSPRTKNAPSLPS- 990
++E+RA + RE EEL++ ++ + +S ++ +PS+ S
Sbjct: 1808 -KKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESD 1866
Query: 991 RTCYKTAPGKIEKV----KPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQTLMED--YE 1044
++ +P KI +V K P + + P+ + + +E G+Q+ + + E+ ++
Sbjct: 1867 PEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKE--GSQKALKSAEEMYEEMMHK 1924
Query: 1045 THKSK 1049
THK K
Sbjct: 1925 THKYK 1929
Score = 32.0 bits (71), Expect = 3.3
Identities = 55/270 (20%), Positives = 106/270 (39%), Gaps = 47/270 (17%)
Query: 725 DFSMDNISDSG---ASNETTNALQENSLADFSLPQTPQT------DNPSEGRGEGVSKSF 775
+ M++++DS + E +++L +S + P + + +PS +GE +
Sbjct: 1698 ELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRK 1757
Query: 776 SDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQQGPE 835
+ H + P + ++ L + LL + Q+ I +Q K+ SK S+ ++ +
Sbjct: 1758 ARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQ 1817
Query: 836 ATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQ 895
E + P S P + +SP +E R AE L + P++
Sbjct: 1818 RRRERPKT-------PPSNLSPIEDASPTEELRQA------AEMEELHRSSCSEYSPSI- 1863
Query: 896 PSGPINMEETRPEGSYFS-----KYSEAAELRSTASLLA-TQESDVMVGPFKLRSRKQRT 949
E+ PEG S + + +L + SL + T E +M ++ K
Sbjct: 1864 --------ESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAE 1915
Query: 950 LSMIEEEIR---------AAQEREEELKRQ 970
M EE + AA ER+E +++
Sbjct: 1916 -EMYEEMMHKTHKYKAFPAANERDEVFEKE 1944
Score = 30.8 bits (68), Expect = 7.4
Identities = 29/122 (23%), Positives = 60/122 (49%), Gaps = 24/122 (19%)
Query: 417 EDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPP 476
EDK+ +L + E+E + K++ ELE ER+E+ R +
Sbjct: 3207 EDKQQQQL----DLERELLELEKIKQQRFAEELEWERQEIQRFRE--------------- 3247
Query: 477 QEKT-IEEQLDE-EHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSH 534
QEK ++++L+E + ++ H +++ +ER+AQ +++++ QQQ Q+ H
Sbjct: 3248 QEKIMVQKKLEELQSMKQHLLFQQEEERQAQ---FMMRQETLAQQQLQLEQIQQLQQQLH 3304
Query: 535 ER 536
++
Sbjct: 3305 QQ 3306
Score = 30.4 bits (67), Expect = 9.6
Identities = 63/309 (20%), Positives = 111/309 (35%), Gaps = 50/309 (16%)
Query: 756 QTPQTDNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLEYQA-------------- 801
Q+ + +P G+SKS + F S G SP E ++
Sbjct: 95 QSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMP 154
Query: 802 GLLVQNAIQQAIAEQVDKAVSKTSRDGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVS 861
G L + A++ V+K + + E T ++ + KP+ + +PP
Sbjct: 155 GFLSEVNALSAVSSVVNK-FNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQ 213
Query: 862 SPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSG----------PINMEETRPEGSY 911
P + +PK L++ G P+ + + QP PI P+ +
Sbjct: 214 QPPKP----IPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDH 269
Query: 912 FSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQR 971
L+ AS T+++D++ G S + I++ ++ +
Sbjct: 270 AK-----LPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKS 324
Query: 972 QVLQSTQSPRTKNAPSLPSRTCYKTA--PGKIEKVKPPPSP--TTEGPS--LQPDLAPEE 1025
Q P P+ PS A PG VKPP P TT+ P+ L P P +
Sbjct: 325 Q-------PGPAKPPAQPSGLTKPLAQQPGT---VKPPVQPPGTTKPPAQPLGPAKPPAQ 374
Query: 1026 AAGTQRPKN 1034
G+++P +
Sbjct: 375 QTGSEKPSS 383
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 51.2 bits (121), Expect = 5e-06
Identities = 104/499 (20%), Positives = 195/499 (39%), Gaps = 99/499 (19%)
Query: 5 ELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLR--------EKWLLQGIP 56
E + + Q +AE++KR + + +R++L+EQ + ++ + R EK L+ +
Sbjct: 383 EQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELE 442
Query: 57 AGTAEEEEARRRQSEEDEFRVKQLEDNIQR-LEQEIQTLESEESQISAKEQIILEKLKET 115
EEEE RR++EE++ RV++ ++ I+R LE+E + LE + Q+ ++ ++LE
Sbjct: 443 RRRKEEEE--RRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWRE 500
Query: 116 EKSFKDFQKGFSSTDGDAVNYISSQLPDLPILCSRTAEPSPGQDGTSRAAGVGWENVL-- 173
+ + ++ + +S Q + +P P Q S+ + E
Sbjct: 501 MEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQHSQQPPPPQQERSKPSFHAPEPKAHY 560
Query: 174 -----LKEGESASNATETSGPDMTIK------KPPQLSEDDIWLKSEGDNYSATLLEPAA 222
+E E T S P+ K +PP S + + ++ L PA
Sbjct: 561 EPADRAREVEDRFRKTNHSSPEAQSKQTGRVLEPPVPSRSESFSNGNSESVHPALQRPAE 620
Query: 223 SSLSPDHKNMEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAR 282
+ H +A K+ S H PS ++ HH D
Sbjct: 621 PQVQWSH--------LASLKNNVSPVSRSHSFSDPSPKFA---------HHHLRSQDPCP 663
Query: 283 EIRYLDEVLEANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASR-- 340
R EVL + DS ++ P+PT++ SR
Sbjct: 664 PSR--SEVL-SQSSDS----------------------------KSEAPDPTQKAWSRSD 692
Query: 341 --QAPPHIELSNSSPDPM---------------AEAERTNGHSPSQPR---DALGDSLQV 380
+ PP + + +S P+ ++A + N S +PR + + +
Sbjct: 693 SDEVPPRVPVRTTSRSPVLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPR 752
Query: 381 PVSPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDK-KPSKLFED--DEHEKEQYCI 437
P S SS+ SS S+ G + +F +R+ + + PS+ E+ + E ++
Sbjct: 753 PGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVF 812
Query: 438 RKVRPSEE--MLELEKERR 454
R ++P+ E + L KE R
Sbjct: 813 RPLKPAGEVDLTALAKELR 831
Score = 40.8 bits (94), Expect = 0.007
Identities = 40/203 (19%), Positives = 84/203 (41%), Gaps = 19/203 (9%)
Query: 326 HEATQPEPTERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQPRDAL---GDSLQVPV 382
H + +P ER Q HI+ + E E S + + G+ +
Sbjct: 286 HPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVN 345
Query: 383 SPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRP 442
P +T R R L++E K A ++ L E E+E+Y + +
Sbjct: 346 VPGESTLRRDFLR--------LQQENKERSEAL---RRQQLLQEQQLREQEEYKRQLLAE 394
Query: 443 SEEMLELEKERRELI-----RSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYK 497
++ +E +KE+R + R + ++ + +++ +EE E ++
Sbjct: 395 RQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRA 454
Query: 498 ERKERRAQQEQLLLQKQLQQQQQ 520
E ++RR ++EQ +++QL+++Q+
Sbjct: 455 EEEKRRVEREQEYIRRQLEEEQR 477
Score = 39.7 bits (91), Expect = 0.016
Identities = 27/124 (21%), Positives = 65/124 (52%), Gaps = 8/124 (6%)
Query: 7 HKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEAR 66
+KER +A+ +R++ + + R+Q + + LL + ++ ++K + + E EAR
Sbjct: 363 NKERSEAL--RRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREAR 420
Query: 67 RRQSEEDEFRVKQLEDNIQRL------EQEIQTLESEESQISAKEQIILEKLKETEKSFK 120
R+Q E R ++ + ++ L E+E + E E+ ++ +++ I +L+E ++ +
Sbjct: 421 RQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLE 480
Query: 121 DFQK 124
Q+
Sbjct: 481 VLQQ 484
Score = 37.7 bits (86), Expect = 0.060
Identities = 35/145 (24%), Positives = 63/145 (43%), Gaps = 15/145 (10%)
Query: 404 LKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERR------ELI 457
L+++ + E A + ++ + E +E + + R+ + EE E+E+R E I
Sbjct: 409 LEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYI 468
Query: 458 RSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLL------ 511
R Q ++ + QE+ + + +E H++ ER +R+ QQEQ L
Sbjct: 469 RRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQ-AERLQRQLQQEQAYLLSLQHD 527
Query: 512 --QKQLQQQQQQPPSQLCTAPASSH 534
+ Q QQ PP Q + S H
Sbjct: 528 HRRPHPQHSQQPPPPQQERSKPSFH 552
Score = 32.3 bits (72), Expect = 2.5
Identities = 33/121 (27%), Positives = 57/121 (47%), Gaps = 15/121 (12%)
Query: 405 KKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKK 464
K E ++E E+++ E E E E I V P E L RR+ +R Q K
Sbjct: 316 KDETEYEYSGSEEEEE-----EVPEQEGEPSSIVNV-PGESTL-----RRDFLRLQQENK 364
Query: 465 NPGIAAKWWNPPQEKTIEEQLDEEH---LESHKKYKERKE-RRAQQEQLLLQKQLQQQQQ 520
A + QE+ + EQ + + E K+ +++KE RR +EQ +++ ++QQ+
Sbjct: 365 ERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQE 424
Query: 521 Q 521
+
Sbjct: 425 R 425
>gi|29826321 adducin 1 (alpha) isoform b [Homo sapiens]
Length = 768
Score = 49.7 bits (117), Expect = 2e-05
Identities = 76/337 (22%), Positives = 125/337 (37%), Gaps = 40/337 (11%)
Query: 333 PTERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQP--------RDALGDSLQVPVS- 383
P + +Q NS A E NG SP D + LQ S
Sbjct: 432 PLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDHVKPLLQSLSSG 491
Query: 384 ---PSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKV 440
PS T+ + DG T T+ L + K + + E+ I+
Sbjct: 492 VCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNT---NPKEVQEMRNKIREQNLQDIKTA 548
Query: 441 RPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNP--------PQEKTIEEQLDEEHLES 492
P ++L R L++ + V + I K + P P T L + LE
Sbjct: 549 GPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTT---LTDRELEE 605
Query: 493 HKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQI 552
+++ ERK++ +++ L + +Q+++ PP Q PA H S K +ED+V E
Sbjct: 606 YRREVERKQKGSEEN---LDEAREQKEKSPPDQ----PAVPHPPPSTPIKLEEDLVPEPT 658
Query: 553 ---DFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGG 609
D AA + L + S ++ P L + +RP + + P
Sbjct: 659 TGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAP 718
Query: 610 PPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKE 646
E++ SA + GA P + GS G + S+ K+
Sbjct: 719 VAEEAAPSAVE----EGAAADPGSDGSPGKSPSKKKK 751
Score = 32.0 bits (71), Expect = 3.3
Identities = 24/103 (23%), Positives = 43/103 (41%), Gaps = 3/103 (2%)
Query: 798 EYQAGLLVQNAIQQAIAEQVDKAVSKTSRD-GAEQQGPEATVEEAEAAAFGSEKPQSMFE 856
EYQ ++V D+ + + R+ +Q+G E ++EA S Q
Sbjct: 580 EYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVP 639
Query: 857 PPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSGP 899
P S+P++ + D++P+ +D P LP + P P
Sbjct: 640 HPPPSTPIKLEEDLVPEPTTGDDSDAATFKP--TLPDLSPDEP 680
>gi|110611218 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 48.9 bits (115), Expect = 3e-05
Identities = 38/165 (23%), Positives = 75/165 (45%), Gaps = 18/165 (10%)
Query: 4 AELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEE 63
AELH + + AE R + E+ G QL E ++ + LL+ A A++
Sbjct: 483 AELHSKLQSSEAEVRSKCEELSGLHGQLQEARAENSQLTERIRSIEALLEAGQARDAQDV 542
Query: 64 EARRRQSEEDEFRVKQLEDNIQRLEQE-IQTLESEESQ-----------------ISAKE 105
+A + ++++ + R+K+LE + LE+E I+ E+ E Q ++ E
Sbjct: 543 QASQAEADQQQTRLKELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALATAE 602
Query: 106 QIILEKLKETEKSFKDFQKGFSSTDGDAVNYISSQLPDLPILCSR 150
Q EKL ++ ++ +K + + + + LP+L +L +
Sbjct: 603 QACKEKLHSLTQAKEESEKQLCLIEAQTMEALLALLPELSVLAQQ 647
>gi|110611220 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 48.9 bits (115), Expect = 3e-05
Identities = 38/165 (23%), Positives = 75/165 (45%), Gaps = 18/165 (10%)
Query: 4 AELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEE 63
AELH + + AE R + E+ G QL E ++ + LL+ A A++
Sbjct: 483 AELHSKLQSSEAEVRSKCEELSGLHGQLQEARAENSQLTERIRSIEALLEAGQARDAQDV 542
Query: 64 EARRRQSEEDEFRVKQLEDNIQRLEQE-IQTLESEESQ-----------------ISAKE 105
+A + ++++ + R+K+LE + LE+E I+ E+ E Q ++ E
Sbjct: 543 QASQAEADQQQTRLKELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALATAE 602
Query: 106 QIILEKLKETEKSFKDFQKGFSSTDGDAVNYISSQLPDLPILCSR 150
Q EKL ++ ++ +K + + + + LP+L +L +
Sbjct: 603 QACKEKLHSLTQAKEESEKQLCLIEAQTMEALLALLPELSVLAQQ 647
>gi|109240550 paraspeckle protein 1 [Homo sapiens]
Length = 523
Score = 48.5 bits (114), Expect = 3e-05
Identities = 68/305 (22%), Positives = 116/305 (38%), Gaps = 44/305 (14%)
Query: 384 PSSTTSSRCSSRDGEFTLTTLKKEAKFE-LRAFH-EDKKPSKLFEDDE--HEKEQYCIRK 439
P+ RC DG F LTT + E + F ED P KL + + H++ + R
Sbjct: 208 PARKALERCG--DGAFLLTTTPRPVIVEPMEQFDDEDGLPEKLMQKTQQYHKEREQPPRF 265
Query: 440 VRPS----------EEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEH 489
+P + + E+EK++RE + +EK E H
Sbjct: 266 AQPGTFEFEYASRWKALDEMEKQQREQVDRNI------------REAKEKLEAEMEAARH 313
Query: 490 LESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERAS---MIDKAKED 546
H+ R++ +QE+L ++L+ Q+ Q Q+ H R + + +E+
Sbjct: 314 --EHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRHREQEE 371
Query: 547 IVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPS 606
+ +Q F MEN Q + G PR +I +G S P N PP
Sbjct: 372 LRRQQEGFKP-----NYMENREQEMRMGDMGPR-GAIN-----MGDAFSPAPAGNQGPPP 420
Query: 607 VGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKRGPLSKLWAEDG 666
+ G ++ A+ PG P A + G +++ +GP S++ + G
Sbjct: 421 MMGMNMNNRATIPGPPMGPGPAMGPEGAANMGTPMMPDNGAVHNDRFPQGPPSQMGSPMG 480
Query: 667 EFTSA 671
T +
Sbjct: 481 SRTGS 485
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 47.8 bits (112), Expect = 6e-05
Identities = 61/278 (21%), Positives = 123/278 (44%), Gaps = 38/278 (13%)
Query: 312 PGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNSSPDPMAE-AERTNG------ 364
PG L GG S + EP ER +S Q P + S+P +E AE T
Sbjct: 37 PGPDTLSGG-SGGSESQEEEEPQERNSSPQRP-----AVSAPVGASEIAEETRPGQRELQ 90
Query: 365 -----HSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDK 419
P + + LQ P P + +DG+ L+ L++E + H++
Sbjct: 91 LQQLEQQPEPQQQPQHEQLQQP-QPHLELQQQ-PQQDGQQQLSQLQQEKHQSVH--HQEL 146
Query: 420 KPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEK 479
KP H+++Q ++V +E L++++ +L QA ++ Q++
Sbjct: 147 KPELQLM---HQQQQLQPQQV---QEQQRLQQQQEQLQTQQAQEQQV--------LQQQE 192
Query: 480 TIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQ--QPPSQLCTAPASSHERA 537
+++Q+ E+ L ++ + ++++ QQ++ L Q+Q QQQQ+ Q QL +
Sbjct: 193 QLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQ 252
Query: 538 SMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQ 575
++ + + + + ++ A+ Q QL+ ++ + + Q
Sbjct: 253 QLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQ 290
Score = 38.9 bits (89), Expect = 0.027
Identities = 46/239 (19%), Positives = 100/239 (41%), Gaps = 28/239 (11%)
Query: 429 EHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQL--- 485
E ++ Q + + +E L+ +++++ L + Q + + P +E+ +E +L
Sbjct: 268 EQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPV 327
Query: 486 ---DEEHLESHKKYKERK-ERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMID 541
E+ LE ++ ER+ E QQEQ LQ +LQ++ QQ QL ++ ++
Sbjct: 328 DLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQL-------EQQQQQLE 380
Query: 542 KAKEDIVTEQIDFSAARKQFQL----------MENSRQAVAKGQSTP----RLFSIKPFY 587
+ + + ++ A +++ QL +E A G + P + P Y
Sbjct: 381 QQEVQLELTPVELGAQQQEVQLELTPVQPELQLELVPAAGGGGAAVPGAPAAVVVAPPGY 440
Query: 588 RPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKE 646
+ + + P ++ GP + + A+ ++ A + P+ G G S+ +
Sbjct: 441 VVVQELMVLPAVAAPAVVAIPGPAGSAALTPARQRRRRRARDRPTICGECGKGFSRSTD 499
Score = 34.7 bits (78), Expect = 0.51
Identities = 33/138 (23%), Positives = 72/138 (52%), Gaps = 23/138 (16%)
Query: 3 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEE 62
+ +L ++ LQ + + +Q +E ++ QL +Q+LL Q + + +++ LLQ ++
Sbjct: 247 QGQLQQQLLQQ-QQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQ------QQQ 299
Query: 63 EEARRRQ--------SEEDEFRVKQLEDNI---QRLEQEIQTLESEESQISAKEQIIL-- 109
E+ +++Q EE+E ++ + ++ Q LEQ+ Q LE ++ +EQ L
Sbjct: 300 EQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQL 359
Query: 110 ---EKLKETEKSFKDFQK 124
E+L++ E+ + Q+
Sbjct: 360 KLQEELQQLEQQLEQQQQ 377
>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
sapiens]
Length = 1268
Score = 47.4 bits (111), Expect = 8e-05
Identities = 57/222 (25%), Positives = 96/222 (43%), Gaps = 30/222 (13%)
Query: 3 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEE 62
E E HK +L +AE++KR E + +R++L+EQ + + + RE+ +
Sbjct: 379 ENEEHKRQL--LAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQ---RRHYEEQMRR 433
Query: 63 EEARRRQSEEDEFRVKQLEDNIQRLEQEIQ-TLESEESQISAKEQIILEKLKETEKSFKD 121
EE RRR E E++ KQLE+ QR + +Q L+ E + + + E+ +K
Sbjct: 434 EEERRRAEHEQEYKRKQLEE--QRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYH 491
Query: 122 FQKGFSSTDGDA-------VNYISSQLPDLPILCSRTAEPSPGQDGTSRAAGVGWENVLL 174
+++G S ++ A + + SQ P L S +P+ G G A V V +
Sbjct: 492 YKEGMSPSEKPAWAKEIPHLVAVKSQGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEM 551
Query: 175 KEGESASNATETSGPDMTIKKPP-----QLSEDDIWLKSEGD 211
S D T + PP + + WL+ E D
Sbjct: 552 PRQNS----------DPTSENPPLPTRIEKFDRSSWLRQEED 583
Score = 43.5 bits (101), Expect = 0.001
Identities = 44/198 (22%), Positives = 82/198 (41%), Gaps = 30/198 (15%)
Query: 326 HEATQPEPTERTASRQAPPHIELSNSSPDPMAEAE-RTNGHSPSQPRDALGDSLQVPVSP 384
H + +P ER Q HI+ + E E +G + + G+ + P
Sbjct: 286 HPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLP 345
Query: 385 SSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSE 444
+T R +F L + + E A + + E++EH+++ R+ R
Sbjct: 346 GESTLRR------DFLRLQLANKERSE--ALRRQQLEQQQRENEEHKRQLLAERQKR--- 394
Query: 445 EMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKE--R 502
+E +KE+R + Q + EK + +Q + E +++ R+E R
Sbjct: 395 --IEEQKEQRRRLEEQQRR--------------EKELRKQQEREQRRHYEEQMRREEERR 438
Query: 503 RAQQEQLLLQKQLQQQQQ 520
RA+ EQ +KQL++Q+Q
Sbjct: 439 RAEHEQEYKRKQLEEQRQ 456
>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
sapiens]
Length = 1276
Score = 47.4 bits (111), Expect = 8e-05
Identities = 57/222 (25%), Positives = 96/222 (43%), Gaps = 30/222 (13%)
Query: 3 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEE 62
E E HK +L +AE++KR E + +R++L+EQ + + + RE+ +
Sbjct: 379 ENEEHKRQL--LAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQ---RRHYEEQMRR 433
Query: 63 EEARRRQSEEDEFRVKQLEDNIQRLEQEIQ-TLESEESQISAKEQIILEKLKETEKSFKD 121
EE RRR E E++ KQLE+ QR + +Q L+ E + + + E+ +K
Sbjct: 434 EEERRRAEHEQEYKRKQLEE--QRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYH 491
Query: 122 FQKGFSSTDGDA-------VNYISSQLPDLPILCSRTAEPSPGQDGTSRAAGVGWENVLL 174
+++G S ++ A + + SQ P L S +P+ G G A V V +
Sbjct: 492 YKEGMSPSEKPAWAKEIPHLVAVKSQGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEM 551
Query: 175 KEGESASNATETSGPDMTIKKPP-----QLSEDDIWLKSEGD 211
S D T + PP + + WL+ E D
Sbjct: 552 PRQNS----------DPTSENPPLPTRIEKFDRSSWLRQEED 583
Score = 43.5 bits (101), Expect = 0.001
Identities = 44/198 (22%), Positives = 82/198 (41%), Gaps = 30/198 (15%)
Query: 326 HEATQPEPTERTASRQAPPHIELSNSSPDPMAEAE-RTNGHSPSQPRDALGDSLQVPVSP 384
H + +P ER Q HI+ + E E +G + + G+ + P
Sbjct: 286 HPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLP 345
Query: 385 SSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSE 444
+T R +F L + + E A + + E++EH+++ R+ R
Sbjct: 346 GESTLRR------DFLRLQLANKERSE--ALRRQQLEQQQRENEEHKRQLLAERQKR--- 394
Query: 445 EMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKE--R 502
+E +KE+R + Q + EK + +Q + E +++ R+E R
Sbjct: 395 --IEEQKEQRRRLEEQQRR--------------EKELRKQQEREQRRHYEEQMRREEERR 438
Query: 503 RAQQEQLLLQKQLQQQQQ 520
RA+ EQ +KQL++Q+Q
Sbjct: 439 RAEHEQEYKRKQLEEQRQ 456
>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
Length = 1312
Score = 47.4 bits (111), Expect = 8e-05
Identities = 83/367 (22%), Positives = 134/367 (36%), Gaps = 57/367 (15%)
Query: 332 EPTERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSR 391
+PTER Q HI+ S E E +S S+ D DS PSS +
Sbjct: 292 QPTERQVRIQLKDHIDRSRKKRGEKEETEYE--YSGSEEED---DSHGEEGEPSSIMNV- 345
Query: 392 CSSRDGEFTLTT----LKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEML 447
GE TL L++E K A K+ +L + + + E + + + +
Sbjct: 346 ----PGESTLRREFLRLQQENKSNSEAL---KQQQQLQQQQQRDPEAHIKHLLHQRQRRI 398
Query: 448 ELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEE------QLDEEHLESHKKYK---- 497
E +KE R + Q ++ K Q++ +E+ + + E ++YK
Sbjct: 399 EEQKEERRRVEEQQRRERE--QRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKRKQL 456
Query: 498 ------ERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASM------IDKAKE 545
ER +R+ QQE L+ QQQQQQ + +R + ++ A +
Sbjct: 457 EEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRGMNPADK 516
Query: 546 DIVTEQIDFSAARKQFQLMENSRQAVAKGQST---PRLFSIKPFYRPLGSVNSDKPLTNP 602
+++ R + +NS A +K ST P + P P G ++ P+ P
Sbjct: 517 PAWAREVE---ERTRMNKQQNSPLAKSKPGSTGPEPPIPQASP--GPPGPLSQTPPMQRP 571
Query: 603 RPPSVG-------GPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKR 655
P G P + A A P A+ P+A S + P SE
Sbjct: 572 VEPQEGPHKSLQDQPTRNLAAFPASHDPDP-AIPAPTATPSARGAVIRQNSDPTSEGPGP 630
Query: 656 GPLSKLW 662
P W
Sbjct: 631 SPNPPAW 637
Score = 39.3 bits (90), Expect = 0.021
Identities = 31/134 (23%), Positives = 65/134 (48%), Gaps = 17/134 (12%)
Query: 9 ERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRR 68
+R + I E+++ + +E ++++ EQ L + + + L + L+ EE RR+
Sbjct: 393 QRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALR--------REEERRQ 444
Query: 69 QSEEDEFRVKQLEDNIQ--RLEQEIQ-------TLESEESQISAKEQIILEKLKETEKSF 119
E E++ KQLE+ Q RL++++Q +L+ ++ Q ++Q + L K
Sbjct: 445 AEREQEYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPL 504
Query: 120 KDFQKGFSSTDGDA 133
+ +G + D A
Sbjct: 505 YHYGRGMNPADKPA 518
Score = 32.0 bits (71), Expect = 3.3
Identities = 44/210 (20%), Positives = 82/210 (39%), Gaps = 6/210 (2%)
Query: 878 EDRALRERGPPQPLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMV 937
ED + E G P + V + E R + S SEA L+ L Q+ D
Sbjct: 329 EDDSHGEEGEPSSIMNVPGESTLRREFLRLQQENKSN-SEA--LKQQQQLQQQQQRDPEA 385
Query: 938 GPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTA 997
L ++QR + +EE R +E++ + QR++ + Q R ++ +L + A
Sbjct: 386 HIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQA 445
Query: 998 PGKIEKVKPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDS 1057
+ E + + LQ L E A + Q ++ + + +R
Sbjct: 446 EREQEYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLY 505
Query: 1058 SYTSKLLSCKVTS---EVLEATRVNRRKSA 1084
Y + + EV E TR+N+++++
Sbjct: 506 HYGRGMNPADKPAWAREVEERTRMNKQQNS 535
Score = 32.0 bits (71), Expect = 3.3
Identities = 31/131 (23%), Positives = 66/131 (50%), Gaps = 16/131 (12%)
Query: 3 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQIL---------LLQHSKSKVLREKWLLQ 53
E+ L +E L+ + ++ K +E ++QQL +Q LL + ++ +K +
Sbjct: 348 ESTLRREFLR-LQQENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERR 406
Query: 54 GIPAGTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLK 113
+ E E R+ Q +E + ++LED +Q L +E + ++E Q ++Q LE+ +
Sbjct: 407 RVEEQQRREREQRKLQEKEQQ---RRLED-MQALRREEERRQAEREQEYKRKQ--LEEQR 460
Query: 114 ETEKSFKDFQK 124
++E+ + Q+
Sbjct: 461 QSERLQRQLQQ 471
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 47.4 bits (111), Expect = 8e-05
Identities = 34/120 (28%), Positives = 65/120 (54%), Gaps = 10/120 (8%)
Query: 1 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA 60
MA +E + +AEKR++ E +++ +EQ LQ + K +RE+ L + A
Sbjct: 590 MAGTTDREEATRLLAEKRRQARE----QREREEQERRLQAERDKRMREEQLAREAEARAE 645
Query: 61 EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK 120
E EARRR+ +E + + ++ +RL++ + EE++ ++E+ ++L E EK F+
Sbjct: 646 REAEARRREEQEAREKAQAEQEEQERLQK-----QKEEAEARSREEAERQRL-EREKHFQ 699
Score = 45.4 bits (106), Expect = 3e-04
Identities = 69/321 (21%), Positives = 122/321 (38%), Gaps = 57/321 (17%)
Query: 331 PEPTERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSS 390
P P+ + APP E P AE S P A PV+PS +
Sbjct: 545 PAPSPAPSPTPAPPQKE------QPPAETPTDAAVLTSPPAPA------PPVTPSKPMAG 592
Query: 391 RCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELE 450
+ L +++A+ + E +E E+ R R EE L E
Sbjct: 593 TTDREEATRLLAEKRRQAREQR-------------EREEQERRLQAERDKRMREEQLARE 639
Query: 451 KERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKER-RAQQEQL 509
E R ++A ++ A +EK EQ ++E L+ K+ E + R A++++L
Sbjct: 640 AEARAEREAEARRREEQEA-------REKAQAEQEEQERLQKQKEEAEARSREEAERQRL 692
Query: 510 LLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQ 569
+K QQQ+Q+ ER +++ + T + + S +++ ++S++
Sbjct: 693 EREKHFQQQEQE-----------RQERRKRLEEIMKR--TRKSEVSETKQK----QDSKE 735
Query: 570 AVAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALE 629
A A G S + +++ L K P+ P P ++ AS G +
Sbjct: 736 ANANGSSPEPVKAVEARSPGLQKEAVQKEEPIPQEPQWSLPSKELPASLVNGLQ------ 789
Query: 630 TPSAAGSQGNTASQGKEGPYS 650
P A + ++ G G S
Sbjct: 790 -PLPAHQENGFSTNGPSGDKS 809
Score = 43.1 bits (100), Expect = 0.001
Identities = 47/209 (22%), Positives = 89/209 (42%), Gaps = 21/209 (10%)
Query: 3 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEE 62
E E + RLQA +KR R+ ++ + + E+ + + + REK AE+
Sbjct: 615 EREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREK--------AQAEQ 666
Query: 63 EEARRRQSEEDEFRVKQLED-NIQRLEQE--IQTLESEESQISAKEQIILEK-----LKE 114
EE R Q +++E + E+ QRLE+E Q E E + + + I+++ + E
Sbjct: 667 EEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSE 726
Query: 115 TEKSFKDFQKGFSSTDGDAVNYISSQLPDLPILCSRTAEPSPGQDG---TSRAAGVGWEN 171
T++ + + + + V + ++ P L + EP P + S+ N
Sbjct: 727 TKQKQDSKEANANGSSPEPVKAVEARSPGLQKEAVQKEEPIPQEPQWSLPSKELPASLVN 786
Query: 172 VLLKEGESASNATETSGP--DMTIKKPPQ 198
L N T+GP D ++ + P+
Sbjct: 787 GLQPLPAHQENGFSTNGPSGDKSLSRTPE 815
Score = 40.0 bits (92), Expect = 0.012
Identities = 48/213 (22%), Positives = 87/213 (40%), Gaps = 23/213 (10%)
Query: 317 LVGGLSPPVHEATQPEPTERTASRQAPPHIELSNSSPD------PMAEAERTNGHSPSQP 370
L G P V T PEP +PP +S PD P + ++ P +P
Sbjct: 9 LGAGAPPAVVARTPPEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEP 68
Query: 371 RDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEH 430
G P P + S + G ++A+ R+ P+ + D
Sbjct: 69 ESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRS--SQPSPTAVPASDSP 126
Query: 431 EKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAK--WWNPPQEKTIEEQLDEE 488
+Q +V+ + E +L KERRE ++ +AAK W +EK + L E+
Sbjct: 127 PTKQ----EVKKAGERHKLAKERRE-------ERAKYLAAKKAVWLEKEEKA--KALREK 173
Query: 489 HLESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 521
L+ ++ E + +A+Q + L+++ +Q+ ++
Sbjct: 174 QLQERRRRLEEQRLKAEQRRAALEERQRQKLEK 206
Score = 31.2 bits (69), Expect = 5.7
Identities = 33/147 (22%), Positives = 53/147 (36%), Gaps = 22/147 (14%)
Query: 857 PPQVSSPVQEKRD---VLPKILPAEDRALRERGPPQPLPAVQPSGPINMEETRPEGSYFS 913
PPQ SP E + P + P + R R P P P +E + G
Sbjct: 81 PPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHK 140
Query: 914 KYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQV 973
E E R A LA +++ +E+E +A RE++L+ +R+
Sbjct: 141 LAKERREER--AKYLAAKKA-----------------VWLEKEEKAKALREKQLQERRRR 181
Query: 974 LQSTQSPRTKNAPSLPSRTCYKTAPGK 1000
L+ + + +L R K K
Sbjct: 182 LEEQRLKAEQRRAALEERQRQKLEKNK 208
Score = 30.4 bits (67), Expect = 9.6
Identities = 21/74 (28%), Positives = 37/74 (50%)
Query: 19 KRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEEDEFRVK 78
K + E K + + L + K+K LREK L + + +A +R++ +E + +
Sbjct: 143 KERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLKAEQRRAALEERQRQ 202
Query: 79 QLEDNIQRLEQEIQ 92
+LE N +R E IQ
Sbjct: 203 KLEKNKERYEAAIQ 216
>gi|29826319 adducin 1 (alpha) isoform a [Homo sapiens]
Length = 737
Score = 46.6 bits (109), Expect = 1e-04
Identities = 63/275 (22%), Positives = 109/275 (39%), Gaps = 30/275 (10%)
Query: 383 SPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRP 442
SP S T + + DG T T+ L + K + + E+ I+ P
Sbjct: 465 SPKSKT--KWTKEDGHRTSTSAVPNLFVPLNT---NPKEVQEMRNKIREQNLQDIKTAGP 519
Query: 443 SEEMLELEKERRELIRSQAVKKNPGIAAKWWNP--------PQEKTIEEQLDEEHLESHK 494
++L R L++ + V + I K + P P T L + LE ++
Sbjct: 520 QSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTT---LTDRELEEYR 576
Query: 495 KYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQI-- 552
+ ERK++ +++ L + +Q+++ PP Q PA H S K +ED+V E
Sbjct: 577 REVERKQKGSEEN---LDEAREQKEKSPPDQ----PAVPHPPPSTPIKLEEDLVPEPTTG 629
Query: 553 -DFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPP 611
D AA + L + S ++ P L + +RP + + P
Sbjct: 630 DDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA 689
Query: 612 EDSGASAAKGQKSPGALETPSAAGSQGNTASQGKE 646
E++ SA + GA P + GS G + S+ K+
Sbjct: 690 EEAAPSAVE----EGAAADPGSDGSPGKSPSKKKK 720
Score = 32.0 bits (71), Expect = 3.3
Identities = 24/103 (23%), Positives = 43/103 (41%), Gaps = 3/103 (2%)
Query: 798 EYQAGLLVQNAIQQAIAEQVDKAVSKTSRD-GAEQQGPEATVEEAEAAAFGSEKPQSMFE 856
EYQ ++V D+ + + R+ +Q+G E ++EA S Q
Sbjct: 549 EYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVP 608
Query: 857 PPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSGP 899
P S+P++ + D++P+ +D P LP + P P
Sbjct: 609 HPPPSTPIKLEEDLVPEPTTGDDSDAATFKP--TLPDLSPDEP 649
>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
sapiens]
Length = 1297
Score = 46.2 bits (108), Expect = 2e-04
Identities = 57/277 (20%), Positives = 113/277 (40%), Gaps = 35/277 (12%)
Query: 326 HEATQPEPTERTASRQAPPHIELSNSSPDPMAEAE-RTNGHSPSQPRDALGDSLQVPVSP 384
H + +P ER Q HI+ + E E +G + + G+ + P
Sbjct: 286 HPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLP 345
Query: 385 SSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSE 444
+T R +F L + + E A + + E++EH+++ R+ R
Sbjct: 346 GESTLRR------DFLRLQLANKERSE--ALRRQQLEQQQRENEEHKRQLLAERQKR--- 394
Query: 445 EMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKE--R 502
+E +KE+R + Q + EK + +Q + E +++ R+E R
Sbjct: 395 --IEEQKEQRRRLEEQQRR--------------EKELRKQQEREQRRHYEEQMRREEERR 438
Query: 503 RAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQ 562
RA+ EQ +++QL+++Q+Q HE+A +++ ++ + EQ ++Q +
Sbjct: 439 RAEHEQEYIRRQLEEEQRQLE---ILQQQLLHEQALLLEYKRKQL-EEQRQAERLQRQLK 494
Query: 563 LMENSRQAVAKGQSTPRLFSIKPFYR-PLGSVNSDKP 598
+ ++ + R KP Y G S+KP
Sbjct: 495 QERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKP 531
Score = 41.6 bits (96), Expect = 0.004
Identities = 34/115 (29%), Positives = 62/115 (53%), Gaps = 5/115 (4%)
Query: 3 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEE 62
E E HK +L +AE++KR E + +R++L+EQ + + + RE+ +
Sbjct: 379 ENEEHKRQL--LAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQ---RRHYEEQMRR 433
Query: 63 EEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEK 117
EE RRR E E+ +QLE+ ++LE Q L E++ + ++ LE+ ++ E+
Sbjct: 434 EEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAER 488
>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
sapiens]
Length = 1305
Score = 46.2 bits (108), Expect = 2e-04
Identities = 57/277 (20%), Positives = 113/277 (40%), Gaps = 35/277 (12%)
Query: 326 HEATQPEPTERTASRQAPPHIELSNSSPDPMAEAE-RTNGHSPSQPRDALGDSLQVPVSP 384
H + +P ER Q HI+ + E E +G + + G+ + P
Sbjct: 286 HPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLP 345
Query: 385 SSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSE 444
+T R +F L + + E A + + E++EH+++ R+ R
Sbjct: 346 GESTLRR------DFLRLQLANKERSE--ALRRQQLEQQQRENEEHKRQLLAERQKR--- 394
Query: 445 EMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKE--R 502
+E +KE+R + Q + EK + +Q + E +++ R+E R
Sbjct: 395 --IEEQKEQRRRLEEQQRR--------------EKELRKQQEREQRRHYEEQMRREEERR 438
Query: 503 RAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQ 562
RA+ EQ +++QL+++Q+Q HE+A +++ ++ + EQ ++Q +
Sbjct: 439 RAEHEQEYIRRQLEEEQRQLE---ILQQQLLHEQALLLEYKRKQL-EEQRQAERLQRQLK 494
Query: 563 LMENSRQAVAKGQSTPRLFSIKPFYR-PLGSVNSDKP 598
+ ++ + R KP Y G S+KP
Sbjct: 495 QERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKP 531
Score = 41.6 bits (96), Expect = 0.004
Identities = 34/115 (29%), Positives = 62/115 (53%), Gaps = 5/115 (4%)
Query: 3 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEE 62
E E HK +L +AE++KR E + +R++L+EQ + + + RE+ +
Sbjct: 379 ENEEHKRQL--LAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQ---RRHYEEQMRR 433
Query: 63 EEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEK 117
EE RRR E E+ +QLE+ ++LE Q L E++ + ++ LE+ ++ E+
Sbjct: 434 EEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAER 488
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 46.2 bits (108), Expect = 2e-04
Identities = 38/120 (31%), Positives = 59/120 (49%), Gaps = 11/120 (9%)
Query: 3 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQIL-------LLQHSKSKVLREKWLLQGI 55
E L +ER + ++R+RQ + K QQ +EQ+L Q + K E+ L Q
Sbjct: 941 EQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEE 1000
Query: 56 PAGTAEEEEARRRQSEEDEFRVK----QLEDNIQRLEQEIQTLESEESQISAKEQIILEK 111
EE E RRRQ E ++R K Q E+ + R E+E + L+ E Q +E++ E+
Sbjct: 1001 EQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEE 1060
Score = 43.5 bits (101), Expect = 0.001
Identities = 31/141 (21%), Positives = 69/141 (48%), Gaps = 3/141 (2%)
Query: 413 RAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSE--EMLELEKERRELIRSQAVKKNPGIAA 470
R F E+++ + KE+ +++ P E+ E E++ R+L R + ++
Sbjct: 236 RVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQ 295
Query: 471 KWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAP 530
+ +E+ + + +EE E ++ +E++ERR QQE+ ++QL+++Q++ Q
Sbjct: 296 QQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE-RREQQLRREQEERREQQLRRE 354
Query: 531 ASSHERASMIDKAKEDIVTEQ 551
R + + +E+ EQ
Sbjct: 355 QEEERREQQLRREQEEERREQ 375
Score = 43.1 bits (100), Expect = 0.001
Identities = 41/187 (21%), Positives = 91/187 (48%), Gaps = 12/187 (6%)
Query: 404 LKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKE-RRELIRSQAV 462
L +E + EL+ +K+ + E E+EQ + E++L E+E RR R +
Sbjct: 905 LLQEEEEELQREEREKRRRQEQERQYREEEQL----QQEEEQLLREEREKRRRQERERQY 960
Query: 463 KKNPGIAAKWWNPPQEKTIEEQLDEEHL-ESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 521
+K+ + K +E+ + E+ ++ E KKY+E +E + ++EQLL +++ ++++Q+
Sbjct: 961 RKDKKLQQK-----EEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQE 1015
Query: 522 PPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLF 581
Q E ++ + +E ++ + R++ +L + Q + + + T R
Sbjct: 1016 WERQYRKKDELQQEEEQLLREEREKRRLQERE-RQYREEEELQQEEEQLLGEERETRRRQ 1074
Query: 582 SIKPFYR 588
++ YR
Sbjct: 1075 ELERQYR 1081
Score = 41.6 bits (96), Expect = 0.004
Identities = 29/152 (19%), Positives = 69/152 (45%)
Query: 411 ELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAA 470
E R E+++ +L + E +EQ R+ +L +E+ E R Q +++ +
Sbjct: 326 ERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRR 385
Query: 471 KWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAP 530
+ +++ EQ + ++ + R+E++ ++EQ L ++Q +++ +Q Q
Sbjct: 386 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQ 445
Query: 531 ASSHERASMIDKAKEDIVTEQIDFSAARKQFQ 562
E+ D K + TE+ + ++Q +
Sbjct: 446 RLKREQEERRDWLKREEETERHEQERRKQQLK 477
Score = 41.6 bits (96), Expect = 0.004
Identities = 35/176 (19%), Positives = 84/176 (47%), Gaps = 9/176 (5%)
Query: 404 LKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVK 463
L++E + + ++++ +L + +E ++Q R R EE LE +R E+ R + +
Sbjct: 558 LEQERREQRLKREQEERRDQLLKREEERRQQ---RLKREQEERLEQRLKREEVERLEQEE 614
Query: 464 KNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPP 523
+ + P+E+ ++ L E E ++ + R+E++ ++EQ L +++ +++ +Q
Sbjct: 615 RREQRLKR--EEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRL 672
Query: 524 SQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPR 579
+ R + + +++ E+I + Q+QL + +K S PR
Sbjct: 673 KR----EHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPR 724
Score = 41.6 bits (96), Expect = 0.004
Identities = 43/185 (23%), Positives = 79/185 (42%), Gaps = 36/185 (19%)
Query: 405 KKEAKFELRAFHEDKKPSK-----LFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRS 459
K+ + R + +DKK + L E+ E + Q +K R EE L++E +L+R
Sbjct: 950 KRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEE---LQQEEEQLLRE 1006
Query: 460 QAVKKNPGIAAKWWNPPQEKTIEEQLDEEHL-----------ESHKKYKERKERRAQQEQ 508
+ K+ + W K E Q +EE L E ++Y+E +E + ++EQ
Sbjct: 1007 EREKRR----RQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQ 1062
Query: 509 LL-----------LQKQLQQQQ--QQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFS 555
LL L++Q ++++ QQ QL R + +E+ +Q +
Sbjct: 1063 LLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQ 1122
Query: 556 AARKQ 560
R++
Sbjct: 1123 LLREE 1127
Score = 41.6 bits (96), Expect = 0.004
Identities = 34/132 (25%), Positives = 68/132 (51%), Gaps = 8/132 (6%)
Query: 397 GEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERREL 456
GE T ++E + + R E ++ + +E EK + R+ R E EL++E +L
Sbjct: 1065 GEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERE-RQCREEEELQQEEEQL 1123
Query: 457 IRSQAVKKNPGIAAKWWNPPQE-KTIEEQLDEEHLESHKK------YKERKERRAQQEQL 509
+R + K+ + + +E + EEQL E E ++ Y+E +E + ++EQL
Sbjct: 1124 LREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQL 1183
Query: 510 LLQKQLQQQQQQ 521
L ++Q +++Q++
Sbjct: 1184 LREEQEKRRQER 1195
Score = 41.2 bits (95), Expect = 0.005
Identities = 45/194 (23%), Positives = 89/194 (45%), Gaps = 23/194 (11%)
Query: 395 RDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERR 454
RD +F L K + + R F ED++ + ++ + + Q RK R E++L+ E+E +
Sbjct: 1577 RDRKFRLEEQKVRRQEQERKFMEDEQQLRR-QEGQQQLRQERDRKFREDEQLLQ-EREEQ 1634
Query: 455 ELIRSQAVKKNPGIAAKWWNPPQEKTI----------EEQLDEEHLESHKKYKERKERRA 504
+L R + +K + +E+ + EEQL +E E + +ER +
Sbjct: 1635 QLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFR 1694
Query: 505 QQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLM 564
++EQ L +++ +++ Q QL R + K +E+ EQ+ ++Q +
Sbjct: 1695 EEEQQLRRQERERKFLQEEQQL--------RRQELERKFREE---EQLRQETEQEQLRRQ 1743
Query: 565 ENSRQAVAKGQSTP 578
E R+ + + Q P
Sbjct: 1744 ERYRKILEEEQLRP 1757
Score = 40.0 bits (92), Expect = 0.012
Identities = 35/125 (28%), Positives = 64/125 (51%), Gaps = 19/125 (15%)
Query: 3 EAELHKERLQAIAEKR----KRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAG 58
E E ++RL+ E+R KR+ E E Q+ +Q L+ + + RE+WL
Sbjct: 439 EQERREQRLKREQEERRDWLKREEETERHEQERRKQ--QLKRDQEEERRERWL------- 489
Query: 59 TAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEE---SQISAKEQIILEKLKET 115
EEE RR Q E E ++++ ++ +R EQ ++ E EE ++ +++Q+ E+ +
Sbjct: 490 -KLEEEERREQQERREQQLRREQE--ERREQRLKRQEEEERLQQRLRSEQQLRREQEERR 546
Query: 116 EKSFK 120
E+ K
Sbjct: 547 EQLLK 551
Score = 40.0 bits (92), Expect = 0.012
Identities = 37/132 (28%), Positives = 63/132 (47%), Gaps = 17/132 (12%)
Query: 3 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQIL-------LLQHSKSKVLREKWLLQGI 55
E L +ER + ++R+RQ E + QQ +EQ+L Q + + +E+ L Q
Sbjct: 1031 EQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEE 1090
Query: 56 PAGTAEEEEARRRQSEE----DEFRVKQLEDNIQRLE------QEIQTLESEESQISAKE 105
EE E RRRQ E +E ++Q E+ + R E QE++ EE ++ +E
Sbjct: 1091 EQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEE 1150
Query: 106 QIILEKLKETEK 117
+ +L + E +
Sbjct: 1151 EQLLREEPEKRR 1162
Score = 38.9 bits (89), Expect = 0.027
Identities = 34/117 (29%), Positives = 57/117 (48%), Gaps = 17/117 (14%)
Query: 8 KERLQAIAEKRKRQTEIEGK-------RQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA 60
+ER E++ R+ E+E K RQ+ +++ L Q K+L E+ L
Sbjct: 1705 RERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRP------E 1758
Query: 61 EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEK 117
EE+ RRQ + +FR E+ R E+E Q L S+ES +E+ L + +E ++
Sbjct: 1759 REEQQLRRQERDRKFR----EEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQ 1811
Score = 38.5 bits (88), Expect = 0.035
Identities = 32/138 (23%), Positives = 66/138 (47%), Gaps = 17/138 (12%)
Query: 416 HEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNP 475
HE ++ + + ++ E+ + R+ E E E+ +++L R Q ++ + W
Sbjct: 438 HEQERREQRLKREQEERRDWLKRE--EETERHEQERRKQQLKRDQEEERR-----ERWLK 490
Query: 476 PQEKTIEEQLDEEHLESHKKYKERKERRA--QQEQLLLQKQLQQQQQQPPSQLCTAPASS 533
+E+ EQ + + ++ +ER+E+R Q+E+ LQ++L+ +QQ Q
Sbjct: 491 LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ-------- 542
Query: 534 HERASMIDKAKEDIVTEQ 551
ER + K +E+ EQ
Sbjct: 543 EERREQLLKREEEKRLEQ 560
Score = 38.5 bits (88), Expect = 0.035
Identities = 35/127 (27%), Positives = 65/127 (51%), Gaps = 16/127 (12%)
Query: 3 EAELHKERLQAIAEK--------RKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQG 54
E EL +E Q + E+ R+RQ E + QQ +EQ LL+ + K R++ Q
Sbjct: 1083 EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQ--LLREEREKRRRQELERQY 1140
Query: 55 IPAGTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKE 114
++EE + + E ++ R ++LE R +E + L+ EE Q+ +EQ ++ +E
Sbjct: 1141 REEEEVQQEEEQLLREEPEKRRRQELE----RQYREEEELQQEEEQLLREEQ--EKRRQE 1194
Query: 115 TEKSFKD 121
E+ +++
Sbjct: 1195 RERQYRE 1201
Score = 38.5 bits (88), Expect = 0.035
Identities = 37/144 (25%), Positives = 70/144 (48%), Gaps = 19/144 (13%)
Query: 391 RCSSRDGEFT---LTTLKKEAKF--ELRAFHEDKKPSKLFEDDEH--------EKEQYCI 437
R RD +F L + + E KF E + H ++ K ++++ ++ Q
Sbjct: 1495 RRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRD 1554
Query: 438 RKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHL---ESHK 494
RK R EE L E+E ++L R + +K K QE+ E DE+ L E +
Sbjct: 1555 RKFR-EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFME--DEQQLRRQEGQQ 1611
Query: 495 KYKERKERRAQQEQLLLQKQLQQQ 518
+ ++ ++R+ ++++ LLQ++ +QQ
Sbjct: 1612 QLRQERDRKFREDEQLLQEREEQQ 1635
Score = 38.5 bits (88), Expect = 0.035
Identities = 33/120 (27%), Positives = 56/120 (46%), Gaps = 11/120 (9%)
Query: 1 MAEAELHKERLQAIAEKRKRQT---EIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPA 57
+ E +L ER + +++R E E RQ+ +EQ L Q S K E+ L Q
Sbjct: 1750 LEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQ---- 1805
Query: 58 GTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEK 117
EE+ R Q + ++R + E+ +Q EQE + + + Q A+EQ ++ E+
Sbjct: 1806 --EREEQQLRPQQRDGKYRWE--EEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREE 1861
Score = 38.1 bits (87), Expect = 0.046
Identities = 29/106 (27%), Positives = 54/106 (50%), Gaps = 11/106 (10%)
Query: 426 EDDEHEKEQYCIRKV-----RPSEEMLELEKERRELI--RSQAVKKNPGIAAKWWNPPQE 478
E E E++Q +R+ + EE E ++ERRE R Q ++ + +E
Sbjct: 289 ERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERRE 348
Query: 479 KTIEEQLDEEHLESHKKYKERKERRAQQ----EQLLLQKQLQQQQQ 520
+ + + +EE E + ++ +ERR QQ +QL ++QL+++QQ
Sbjct: 349 QQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQ 394
Score = 38.1 bits (87), Expect = 0.046
Identities = 25/101 (24%), Positives = 53/101 (52%), Gaps = 3/101 (2%)
Query: 8 KERLQAIAEKRKRQTEIEGKRQQL--DEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEA 65
+E + + ++ KR+ E E + Q+L +EQ + KS++ + +W L+ A + +
Sbjct: 662 EEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLES-EADARQSKVY 720
Query: 66 RRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQ 106
R + +E + R ++ E+ +R E E+Q E E + +E+
Sbjct: 721 SRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEE 761
Score = 38.1 bits (87), Expect = 0.046
Identities = 43/186 (23%), Positives = 81/186 (43%), Gaps = 21/186 (11%)
Query: 398 EFTLTTLKKEAKF--ELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRE 455
E L +++ KF E + ++ K ++++ + Q RK R EE L E E+ +
Sbjct: 1681 EQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFR-EEEQLRQETEQEQ 1739
Query: 456 LIRSQAVKKNPGIAAKWWNPPQEKTI------------EEQLDEEHLESHKKYKERKERR 503
L R + +K + + P +E+ EEQL +E E + +E +
Sbjct: 1740 LRRQERYRKI--LEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKF 1797
Query: 504 AQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQL 563
++EQL +Q +++QQ P Q E +++ ++ + E+ A +QF
Sbjct: 1798 REEEQL---RQEREEQQLRPQQR-DGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFAT 1853
Query: 564 MENSRQ 569
E SR+
Sbjct: 1854 QEKSRR 1859
Score = 37.7 bits (86), Expect = 0.060
Identities = 34/153 (22%), Positives = 67/153 (43%), Gaps = 10/153 (6%)
Query: 424 LFEDDEHEKEQYCIRKVRPSEEMLELE--KERRELIRSQAVKKNPGIAAKWWNPPQEKTI 481
L +D E++Q R+ P + LE E + RR+ + Q + G E+
Sbjct: 109 LLQDRRQEEDQ---RRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRD 165
Query: 482 EEQLDEEHLESHKKYKERKERRAQQEQLLLQK-----QLQQQQQQPPSQLCTAPASSHER 536
++ DEE ++++ER+ERRA++EQL K + ++Q +L E
Sbjct: 166 RQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREE 225
Query: 537 ASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQ 569
+ ++D V ++ + RK+ ++ +
Sbjct: 226 KQQQRRERQDRVFQEEEEKEWRKRETVLRKEEE 258
Score = 37.7 bits (86), Expect = 0.060
Identities = 27/107 (25%), Positives = 55/107 (51%), Gaps = 6/107 (5%)
Query: 16 EKRKRQTEIEGKRQQLD---EQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEE 72
EKR+RQ + R++ + E+ LL+ + K R++W Q ++EE + + E
Sbjct: 979 EKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREER 1038
Query: 73 DEFRVKQLEDNI---QRLEQEIQTLESEESQISAKEQIILEKLKETE 116
++ R+++ E + L+QE + L EE + ++++ + KE E
Sbjct: 1039 EKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE 1085
Score = 37.7 bits (86), Expect = 0.060
Identities = 32/148 (21%), Positives = 69/148 (46%), Gaps = 10/148 (6%)
Query: 405 KKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKK 464
++E ++ + ++ L E+ E + Q R+ R EE L++E +L+R + K+
Sbjct: 1045 ERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE---LQQEEEQLLREEPEKR 1101
Query: 465 NPGIAAKWWNPPQE-KTIEEQLDEEHLESHKK------YKERKERRAQQEQLLLQKQLQQ 517
+ +E + EEQL E E ++ Y+E +E + ++EQLL ++ ++
Sbjct: 1102 RRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKR 1161
Query: 518 QQQQPPSQLCTAPASSHERASMIDKAKE 545
++Q+ Q E ++ + +E
Sbjct: 1162 RRQELERQYREEEELQQEEEQLLREEQE 1189
Score = 37.4 bits (85), Expect = 0.079
Identities = 34/136 (25%), Positives = 70/136 (51%), Gaps = 26/136 (19%)
Query: 405 KKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKK 464
++E + R E +K + E++E + + ++++ E+ L+ ++ERR RSQ ++
Sbjct: 814 EEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERR---RSQEQRR 870
Query: 465 NPGIAAKW-WNPPQEK-----------TIEEQLDEEHL-----ESHKKYKERKERRAQQE 507
+ KW W +E+ ++EQL +E E + +ER++RR Q++
Sbjct: 871 DQ----KWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQ 926
Query: 508 --QLLLQKQLQQQQQQ 521
Q ++QLQQ+++Q
Sbjct: 927 ERQYREEEQLQQEEEQ 942
Score = 37.4 bits (85), Expect = 0.079
Identities = 30/130 (23%), Positives = 65/130 (50%), Gaps = 21/130 (16%)
Query: 395 RDGEFTLTTLKKEAKF---ELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEK 451
R+ E L+ +++ KF E + ++++ L E+ + +E++ RK R E++L+ E+
Sbjct: 1417 REEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERH--RKFREEEQLLQ-ER 1473
Query: 452 ERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLL 511
E ++L R + K +EE+ E +K++E++ R + E+ L
Sbjct: 1474 EEQQLHRQER---------------DRKFLEEEQQLRRQERDRKFREQELRSQEPERKFL 1518
Query: 512 QKQLQQQQQQ 521
+++ Q +QQ
Sbjct: 1519 EEEQQLHRQQ 1528
Score = 36.6 bits (83), Expect = 0.13
Identities = 30/122 (24%), Positives = 60/122 (49%), Gaps = 10/122 (8%)
Query: 3 EAELHKERLQAIAEKRKRQTEIEGK--------RQQLDEQILLLQHSKSKVLREKWLLQG 54
E L KE + E+ +RQ E++ + RQ+L + + + ++ RE+ L +
Sbjct: 250 ETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRK 309
Query: 55 IPAGTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQE--IQTLESEESQISAKEQIILEKL 112
E++E RR Q E E + ++ E ++R ++E Q L E+ + ++Q+ E+
Sbjct: 310 QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQE 369
Query: 113 KE 114
+E
Sbjct: 370 EE 371
Score = 36.6 bits (83), Expect = 0.13
Identities = 27/106 (25%), Positives = 55/106 (51%), Gaps = 6/106 (5%)
Query: 417 EDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPP 476
+ ++ L E+ E + Q R+ R EE+ ++E +L+R + K+ + +
Sbjct: 1117 QQEEEQLLREEREKRRRQELERQYREEEEV---QQEEEQLLREEPEKRRRQELERQYREE 1173
Query: 477 QE-KTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 521
+E + EEQL E E K+ +ER+ + ++E+L QK+ Q+ + +
Sbjct: 1174 EELQQEEEQLLRE--EQEKRRQERERQYREEEELQRQKRKQRYRDE 1217
Score = 36.6 bits (83), Expect = 0.13
Identities = 23/128 (17%), Positives = 60/128 (46%), Gaps = 7/128 (5%)
Query: 398 EFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEML-------ELE 450
E L +++ KF ++ K E+++ + Q RK E+ L +L
Sbjct: 1350 EQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLR 1409
Query: 451 KERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLL 510
++R R + + + + + +++ ++ + + LE ++ ++ + R+ ++E+ L
Sbjct: 1410 QDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQL 1469
Query: 511 LQKQLQQQ 518
LQ++ +QQ
Sbjct: 1470 LQEREEQQ 1477
Score = 36.2 bits (82), Expect = 0.18
Identities = 29/109 (26%), Positives = 61/109 (55%), Gaps = 6/109 (5%)
Query: 10 RLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREK-WLLQGIPAGTAEEEEARRR 68
R + + E R++ E E ++Q+ + Q + Q + K R++ +L+ EEE R+R
Sbjct: 211 RRRELLELRRKGRE-EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQR 269
Query: 69 QSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEK 117
+ +E+E ++++LE Q L +E Q E ++ ++ ++Q L + +E E+
Sbjct: 270 ELQEEEEQLRKLER--QELRRERQEEEQQQQRLRREQQ--LRRKQEEER 314
Score = 36.2 bits (82), Expect = 0.18
Identities = 28/110 (25%), Positives = 57/110 (51%), Gaps = 26/110 (23%)
Query: 411 ELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAA 470
+LR E+++ +L +E E+ Q +R SE+ L E+E R R Q +K+
Sbjct: 506 QLRREQEERREQRLKRQEEEERLQQRLR----SEQQLRREQEER---REQLLKRE----- 553
Query: 471 KWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQ 520
+EK +E++ E+ L ++E+ +++QLL +++ ++QQ+
Sbjct: 554 ------EEKRLEQERREQRL--------KREQEERRDQLLKREEERRQQR 589
Score = 36.2 bits (82), Expect = 0.18
Identities = 32/120 (26%), Positives = 59/120 (49%), Gaps = 6/120 (5%)
Query: 3 EAELHKERLQAIAEKRKRQ----TEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAG 58
E E ++RL+ E+R Q E+E + +Q + + L+ + + R + LL+
Sbjct: 582 EEERRQQRLKREQEERLEQRLKREEVE-RLEQEERREQRLKREEPEEERRQQLLKSEEQE 640
Query: 59 TAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKS 118
+++ RR Q E E R+K+ E+ +RLEQ ++ EE + + E+ +E KS
Sbjct: 641 ERRQQQLRREQQERREQRLKR-EEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699
Score = 36.2 bits (82), Expect = 0.18
Identities = 34/116 (29%), Positives = 52/116 (44%), Gaps = 13/116 (11%)
Query: 16 EKRKRQT------EIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQ 69
EKR+RQ E E Q+ +EQ L Q K E+ Q EEE+ RRQ
Sbjct: 1327 EKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQ 1386
Query: 70 SEEDEFRVKQLEDNIQRLEQEI-----QTLESEESQISAKEQIILEKLKETEKSFK 120
E +F ++ + Q EQ++ + EE Q+S +E+ K +E E+ +
Sbjct: 1387 ERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERD--RKFREEEQQVR 1440
Score = 36.2 bits (82), Expect = 0.18
Identities = 28/114 (24%), Positives = 57/114 (50%), Gaps = 1/114 (0%)
Query: 413 RAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKW 472
R F E + S+ E E+EQ R+ R + L+ E++ R R Q +++ +
Sbjct: 1501 RKFREQELRSQEPERKFLEEEQQLHRQQR-QRKFLQEEQQLRRQERGQQRRQDRDRKFRE 1559
Query: 473 WNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQL 526
+++ E+QL + + + +E+K RR +QE+ ++ + Q ++Q+ QL
Sbjct: 1560 EEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQL 1613
Score = 35.8 bits (81), Expect = 0.23
Identities = 27/99 (27%), Positives = 50/99 (50%), Gaps = 2/99 (2%)
Query: 8 KERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARR 67
+ER + E+ R E E K + +EQ L Q + K L+E+ L+ G ++ R
Sbjct: 1497 QERDRKFREQELRSQEPERKFLE-EEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDR 1555
Query: 68 RQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQ 106
+ EE++ R ++ E + R E++ + EE ++ +EQ
Sbjct: 1556 KFREEEQLRQEREEQQLSRQERD-RKFRLEEQKVRRQEQ 1593
Score = 35.4 bits (80), Expect = 0.30
Identities = 25/94 (26%), Positives = 48/94 (51%), Gaps = 18/94 (19%)
Query: 428 DEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDE 487
++ KEQ ++ EE EL++E RE R Q ++ + EEQL +
Sbjct: 897 EQLRKEQQLLQ-----EEEEELQREEREKRRRQEQER-------------QYREEEQLQQ 938
Query: 488 EHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 521
E + ++ +E++ R+ ++ Q K+LQQ+++Q
Sbjct: 939 EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQ 972
Score = 35.0 bits (79), Expect = 0.39
Identities = 29/127 (22%), Positives = 60/127 (47%), Gaps = 18/127 (14%)
Query: 395 RDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERR 454
RD E + + + E RA E + K E +E E+ R+ E+LEL ++ R
Sbjct: 169 RDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRR-----ELLELRRKGR 223
Query: 455 ELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQ 514
E + Q ++ Q++ +E+ +E+ + ++E + Q+E+ Q++
Sbjct: 224 EEKQQQRRER------------QDRVFQEE-EEKEWRKRETVLRKEEEKLQEEEPQRQRE 270
Query: 515 LQQQQQQ 521
LQ++++Q
Sbjct: 271 LQEEEEQ 277
Score = 35.0 bits (79), Expect = 0.39
Identities = 35/123 (28%), Positives = 58/123 (47%), Gaps = 18/123 (14%)
Query: 3 EAELHKERLQAIAEKRKRQTEIEGKRQ--------QLDEQILLLQHSK------SKVLRE 48
E EL +E Q + E+R+++ E +RQ Q +EQ+L + K + RE
Sbjct: 1113 EEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYRE 1172
Query: 49 KWLLQGIPAGTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQII 108
+ LQ EE+ +RRQ E ++R E+ +QR +++ Q E+ + K Q
Sbjct: 1173 EEELQQEEEQLLREEQEKRRQERERQYRE---EEELQRQKRK-QRYRDEDQRSDLKWQWE 1228
Query: 109 LEK 111
EK
Sbjct: 1229 PEK 1231
Score = 34.7 bits (78), Expect = 0.51
Identities = 26/104 (25%), Positives = 55/104 (52%), Gaps = 9/104 (8%)
Query: 8 KERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARR 67
+ER + E+ ++ E +R+ L+E+ L Q K E+ LLQ EE++ R
Sbjct: 1426 QERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQ-----EREEQQLHR 1480
Query: 68 RQSE----EDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQI 107
++ + E+E ++++ E + + EQE+++ E E + ++Q+
Sbjct: 1481 QERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQL 1524
Score = 34.3 bits (77), Expect = 0.67
Identities = 29/127 (22%), Positives = 62/127 (48%), Gaps = 11/127 (8%)
Query: 395 RDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERR 454
R+ E LK+E + E HE ++ + + D+ E+ + K+ E + E+ +
Sbjct: 449 REQEERRDWLKREEETER---HEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQ 505
Query: 455 ELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQ 514
+L R Q ++ + QE+ EE+L + + +E++ERR Q + +K+
Sbjct: 506 QLRREQEERREQRLKR------QEE--EERLQQRLRSEQQLRREQEERREQLLKREEEKR 557
Query: 515 LQQQQQQ 521
L+Q++++
Sbjct: 558 LEQERRE 564
Score = 34.3 bits (77), Expect = 0.67
Identities = 32/120 (26%), Positives = 63/120 (52%), Gaps = 18/120 (15%)
Query: 411 ELRAFHEDKKPSKLFEDDEH---EKEQYCIR------KVRPSEEMLELEKERRELIRSQA 461
+LR+ D+K F ++E E+E+ +R K R EE L+LE++ + L +
Sbjct: 1787 QLRSQESDRK----FREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQ--- 1839
Query: 462 VKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 521
+++ A+ QEK+ E+ + E K+ +ER ER+ ++E + Q++ +Q+ +Q
Sbjct: 1840 -ERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQER-ERKLREEHIRRQQKEEQRHRQ 1897
Score = 33.9 bits (76), Expect = 0.87
Identities = 36/164 (21%), Positives = 69/164 (42%), Gaps = 11/164 (6%)
Query: 413 RAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELE-------KERRELIRSQAVKKN 465
R F E+++ + E D +EQ +R P + LE E ++R+ L Q +++
Sbjct: 1485 RKFLEEEQQLRRQERDRKFREQE-LRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQ 1543
Query: 466 PGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQ 525
+ + ++ EEQL +E E +ER + +EQ + +++ +++ + Q
Sbjct: 1544 ERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQ 1603
Query: 526 LCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQ 569
L R K +ED EQ+ +Q E R+
Sbjct: 1604 LRRQEGQQQLRQERDRKFRED---EQLLQEREEQQLHRQERDRK 1644
Score = 33.5 bits (75), Expect = 1.1
Identities = 28/123 (22%), Positives = 59/123 (47%), Gaps = 10/123 (8%)
Query: 5 ELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEE 64
E + R Q + + +++ E E + Q+L + + + ++L+ + + +EE
Sbjct: 541 EQEERREQLLKREEEKRLEQERREQRLKRE---QEERRDQLLKREEERRQQRLKREQEER 597
Query: 65 ARRRQSEEDEFRVKQLEDNIQRLEQE-------IQTLESEESQISAKEQIILEKLKETEK 117
+R E+ R++Q E QRL++E Q L+SEE + ++Q+ E+ + E+
Sbjct: 598 LEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQ 657
Query: 118 SFK 120
K
Sbjct: 658 RLK 660
Score = 33.1 bits (74), Expect = 1.5
Identities = 27/133 (20%), Positives = 62/133 (46%), Gaps = 15/133 (11%)
Query: 417 EDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPP 476
++++P + E E E++ + + E E E++++ L R Q +++
Sbjct: 261 QEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRK----------- 309
Query: 477 QEKTIEEQLDE--EHLESHKKYKERKER--RAQQEQLLLQKQLQQQQQQPPSQLCTAPAS 532
QE+ EQ +E E E ++ +ER+E+ R +QE+ Q+ ++Q+++ Q
Sbjct: 310 QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQE 369
Query: 533 SHERASMIDKAKE 545
R + + ++
Sbjct: 370 EERREQQLRREQQ 382
Score = 33.1 bits (74), Expect = 1.5
Identities = 31/127 (24%), Positives = 65/127 (51%), Gaps = 16/127 (12%)
Query: 3 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEE 62
E +L +++ + E+++ + E + +R+Q +E+ + + RE+ L + E+
Sbjct: 303 EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRR-------EQ 355
Query: 63 EEARR----RQSEEDEFRVKQLEDNIQ-RLEQEIQTLESEESQISAKEQIILEKLKETEK 117
EE RR R+ +E+E R +QL Q R EQ+++ E Q+ ++Q+ E+ E+
Sbjct: 356 EEERREQQLRREQEEERREQQLRREQQLRREQQLR----REQQLRREQQLRREQQLRREQ 411
Query: 118 SFKDFQK 124
+ Q+
Sbjct: 412 QLRREQQ 418
Score = 33.1 bits (74), Expect = 1.5
Identities = 25/111 (22%), Positives = 51/111 (45%), Gaps = 4/111 (3%)
Query: 411 ELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAA 470
+LR + ++ +L + + +EQ R+ + E+ERRE Q +K+
Sbjct: 400 QLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERRE----QRLKREQEERR 455
Query: 471 KWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 521
W +E EQ + + +ER+ER + E+ ++Q ++++QQ
Sbjct: 456 DWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ 506
Score = 33.1 bits (74), Expect = 1.5
Identities = 28/118 (23%), Positives = 55/118 (46%), Gaps = 23/118 (19%)
Query: 3 EAELHKERLQA---IAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGT 59
++E ++RL A + E+R+RQ E +RQQ +++ L P
Sbjct: 776 KSERGRQRLSARPPLREQRERQLRAE-ERQQREQRFL-------------------PEEE 815
Query: 60 AEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEK 117
+E+ R+R+ E E + + E+ +QR E+ Q E E+ +E+ ++ + +K
Sbjct: 816 EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQK 873
Score = 33.1 bits (74), Expect = 1.5
Identities = 34/116 (29%), Positives = 57/116 (49%), Gaps = 13/116 (11%)
Query: 3 EAEL-HKERLQAIAEKRKRQTEIEGKRQQL-DEQILLLQHSKSKVLREKWLLQGIPAGTA 60
E EL H+E+ + E+ +R E +R+ L +EQ L Q RE+ L Q
Sbjct: 1364 EEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQE------REQQLRQDRDRKFR 1417
Query: 61 EEEEA-----RRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEK 111
EEE+ R R+ E+E +V++ E + LE+E Q + + +EQ++ E+
Sbjct: 1418 EEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQER 1473
Score = 32.7 bits (73), Expect = 1.9
Identities = 38/175 (21%), Positives = 81/175 (46%), Gaps = 10/175 (5%)
Query: 405 KKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKK 464
++ K +L+ E+++ + + +E E+ + R+ E+ L E+E R R + ++
Sbjct: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQERR----EQQLRREQEERREQRLKRQEE 524
Query: 465 NPGIAAKWWNPPQEKTIEEQLDEEHL---ESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 521
+ + + Q + +E+ E+ L E + +ER+E+R ++EQ + QL +++++
Sbjct: 525 EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEE 584
Query: 522 PPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAAR-KQFQLMENSRQAVAKGQ 575
Q ER K +E EQ + R K+ + E RQ + K +
Sbjct: 585 RRQQ--RLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSE 637
Score = 32.7 bits (73), Expect = 1.9
Identities = 33/140 (23%), Positives = 68/140 (48%), Gaps = 26/140 (18%)
Query: 8 KERLQAIAEKRKRQTEIEGK--RQQLDEQILLLQHS-------KSKVLREKWLLQGIPAG 58
++ LQ E+R+ Q + + R QL+E+ +H+ + ++ +E+ LLQ
Sbjct: 853 EDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEE 912
Query: 59 TAEEEEARRRQSEE-----DEFRVKQLEDNIQRLEQEIQTLESEESQ------ISAKEQI 107
EE +RR+ E+ +E +++Q E+ + R E+E + + E Q + KE+
Sbjct: 913 LQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQ 972
Query: 108 IL------EKLKETEKSFKD 121
+L + +E EK +++
Sbjct: 973 LLGEEPEKRRRQEREKKYRE 992
Score = 32.7 bits (73), Expect = 1.9
Identities = 32/117 (27%), Positives = 61/117 (52%), Gaps = 16/117 (13%)
Query: 3 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEE 62
E EL +E EKR+RQ E +RQ +E+ LQ + ++LRE+ + +E
Sbjct: 910 EEELQREE----REKRRRQ---EQERQYREEE--QLQQEEEQLLREEREKR-----RRQE 955
Query: 63 EEARRRQSEEDEFRVKQL--EDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEK 117
E + R+ ++ + + +QL E+ +R QE + EE ++ +E+ +L + +E +
Sbjct: 956 RERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR 1012
Score = 32.7 bits (73), Expect = 1.9
Identities = 24/119 (20%), Positives = 58/119 (48%), Gaps = 24/119 (20%)
Query: 3 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEE 62
E +LH++ +++ + E + +RQ+ ++Q L+H + + RE
Sbjct: 1633 EQQLHRQE----RDRKFLEEEPQLRRQEREQQ---LRHDRDRKFRE-------------- 1671
Query: 63 EEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKD 121
EE ++ EE + R ++ + + EQ+++ E E + ++Q+ + +E E+ F++
Sbjct: 1672 EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQL---RRQELERKFRE 1727
Score = 32.7 bits (73), Expect = 1.9
Identities = 28/114 (24%), Positives = 56/114 (49%), Gaps = 4/114 (3%)
Query: 413 RAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKW 472
R F E+++ + +++ + Q RK R EE L E+E ++L Q K +
Sbjct: 1771 RKFREEEQ-LRQEREEQQLRSQESDRKFR-EEEQLRQEREEQQLRPQQRDGKYRWEEEQL 1828
Query: 473 WNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQL 526
QE+ + ++ D ++ + + K RR +QE L Q++ Q+++Q+ +L
Sbjct: 1829 QLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQE--LWQEEEQKRRQERERKL 1880
Score = 32.0 bits (71), Expect = 3.3
Identities = 28/177 (15%), Positives = 80/177 (45%), Gaps = 10/177 (5%)
Query: 413 RAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERR-----ELIRSQAVKKNPG 467
R E+++ +L + E E+ + +R+ + +L +E++ +L R Q +++
Sbjct: 353 REQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 412
Query: 468 IAAKWWNPPQEKTIEEQLDE----EHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPP 523
+ + +++ EQ +E +H + ++ + ++E+ +++ L +++ ++ +Q+
Sbjct: 413 LRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR 472
Query: 524 SQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRL 580
Q R + K +E+ EQ + + + + E Q + + + RL
Sbjct: 473 KQQLKRDQEEERRERWL-KLEEEERREQQERREQQLRREQEERREQRLKRQEEEERL 528
Score = 32.0 bits (71), Expect = 3.3
Identities = 28/119 (23%), Positives = 57/119 (47%), Gaps = 5/119 (4%)
Query: 3 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEE 62
E +L +E+ ++ +R+ E E Q+ +++ + + + R WL + E+
Sbjct: 410 EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQ 469
Query: 63 E----EARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEK 117
E + +R Q EE R +LE+ +R +QE + + Q +EQ L++ +E E+
Sbjct: 470 ERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQ-RLKRQEEEER 527
Score = 32.0 bits (71), Expect = 3.3
Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 8/105 (7%)
Query: 8 KERLQAIAEKRKRQ-TEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEAR 66
+ER Q + R R+ E E Q+ +EQ L Q K E+ L+ +E R
Sbjct: 1655 QEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLR-------RQERER 1707
Query: 67 RRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEK 111
+ EE + R ++LE + EQ Q E E+ + + + ILE+
Sbjct: 1708 KFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEE 1752
Score = 32.0 bits (71), Expect = 3.3
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 10/124 (8%)
Query: 3 EAELHKERLQAIAEKRKRQTEI---EGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGT 59
E +L +E Q +++R +I E R + +EQ L Q K E+ L Q
Sbjct: 1728 EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQ------ 1781
Query: 60 AEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSF 119
E EE + R E D ++ + +R EQ+++ + + +EQ+ LE+ ++ +
Sbjct: 1782 -EREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQE 1840
Query: 120 KDFQ 123
+D Q
Sbjct: 1841 RDRQ 1844
Score = 31.6 bits (70), Expect = 4.3
Identities = 31/111 (27%), Positives = 60/111 (54%), Gaps = 13/111 (11%)
Query: 16 EKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARR----RQ-S 70
E++ R+ E E K Q +EQ L Q + K E+ L Q E+E+ RR R+
Sbjct: 1697 EQQLRRQERERKFLQ-EEQQLRRQELERKFREEEQLRQ-----ETEQEQLRRQERYRKIL 1750
Query: 71 EEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKD 121
EE++ R ++ E ++R E++ + E E+ + +EQ + + +E+++ F++
Sbjct: 1751 EEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQL--RSQESDRKFRE 1799
Score = 31.2 bits (69), Expect = 5.7
Identities = 29/119 (24%), Positives = 60/119 (50%), Gaps = 16/119 (13%)
Query: 3 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEE 62
E +LH+++ Q ++ Q E + +RQ+ +Q + + + RE+ L+ E
Sbjct: 1521 EQQLHRQQRQ----RKFLQEEQQLRRQERGQQ---RRQDRDRKFREEEQLR-----QERE 1568
Query: 63 EEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKD 121
E+ RQ + +FR++ E ++R EQE + +E E+ + Q L +E ++ F++
Sbjct: 1569 EQQLSRQERDRKFRLE--EQKVRRQEQERKFMEDEQQLRRQEGQQQLR--QERDRKFRE 1623
Score = 31.2 bits (69), Expect = 5.7
Identities = 25/120 (20%), Positives = 58/120 (48%), Gaps = 7/120 (5%)
Query: 8 KERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARR 67
++R + E++ R+ E E K + DEQ L Q + ++ +E+ +E E ++
Sbjct: 1577 RDRKFRLEEQKVRRQEQERKFME-DEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQ 1635
Query: 68 RQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILE------KLKETEKSFKD 121
+E + + + E ++R E+E Q + + +EQ++ E + +E ++ F++
Sbjct: 1636 LHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFRE 1695
Score = 30.4 bits (67), Expect = 9.6
Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 13/123 (10%)
Query: 1 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA 60
+AE E E+ + + ++ +++ + E RQ+ + Q + + E+ LQ
Sbjct: 148 LAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQ------EREERRAEEEQLQSCKGHET 201
Query: 61 EE--EEARRRQSEEDEFRVKQLEDNIQ-RLEQEIQTLESEESQISAKEQIIL----EKLK 113
EE +E + R+ E E R K E+ Q R E++ + + EE + K + +L EKL+
Sbjct: 202 EEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQ 261
Query: 114 ETE 116
E E
Sbjct: 262 EEE 264
Score = 30.4 bits (67), Expect = 9.6
Identities = 27/115 (23%), Positives = 54/115 (46%), Gaps = 22/115 (19%)
Query: 8 KERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARR 67
+E+LQ ++ Q E +G ++ + + S+ + +KW Q EEE RR
Sbjct: 837 EEQLQRRERAQQLQEEEDGLQEDQERR-----RSQEQRRDQKWRWQ------LEEERKRR 885
Query: 68 R-----------QSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEK 111
R Q +++ +++ E+ +QR E+E + + +E Q +EQ+ E+
Sbjct: 886 RHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEE 940
Score = 30.4 bits (67), Expect = 9.6
Identities = 33/185 (17%), Positives = 81/185 (43%), Gaps = 14/185 (7%)
Query: 406 KEAKFELRAFHEDKK----PSKLFEDDEH---EKEQYCIRKVRPS----EEMLELEKERR 454
+E K LR E+K+ + F ++E E+E+ +R+ EE L +++ R
Sbjct: 1315 QEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGR 1374
Query: 455 ELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQ 514
+ + + + K+ Q+ +E+ + + +K++E +++ ++QE+ ++
Sbjct: 1375 KFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQER---DRK 1431
Query: 515 LQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKG 574
++++QQ Q E+ ++ ++ EQ+ +Q E R+ + +
Sbjct: 1432 FREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEE 1491
Query: 575 QSTPR 579
Q R
Sbjct: 1492 QQLRR 1496
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 46.2 bits (108), Expect = 2e-04
Identities = 34/109 (31%), Positives = 60/109 (55%), Gaps = 9/109 (8%)
Query: 14 IAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEED 73
+A+ + E+E +++QL + + LL+ S K R + QG+ E + ++ E
Sbjct: 720 MAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDI----ENQRLQKTLENS 775
Query: 74 EFRVKQLEDNIQRLEQEIQTLES--EESQISAKEQIILEKLKETEKSFK 120
+++QLE +Q LE E QTL+ EE +IS+K LE+L++ KS +
Sbjct: 776 NKKIQQLESELQDLEMENQTLQKNLEELKISSKR---LEQLEKENKSLE 821
Score = 36.6 bits (83), Expect = 0.13
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 23/199 (11%)
Query: 388 TSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEH--EKEQYCIRKVRPS-- 443
TSS+ S + E K++ K EL + E + ++ E++ H EKE ++K +
Sbjct: 599 TSSKLSKIEFE------KRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLK 652
Query: 444 ---EEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEE--QLDEEHLESHKKYKE 498
E++ LE+E EL R K + K E +E QLDEE+LE + +
Sbjct: 653 ITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVES 712
Query: 499 RKERRAQQEQLLLQ-KQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAA 557
K + QL L+ K+L+ +++Q L AS + + ++ + +D
Sbjct: 713 LKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERL------EVSYQGLDIENQ 766
Query: 558 RKQFQLMENSRQAVAKGQS 576
R Q + +ENS + + + +S
Sbjct: 767 RLQ-KTLENSNKKIQQLES 784
Score = 33.1 bits (74), Expect = 1.5
Identities = 33/125 (26%), Positives = 62/125 (49%), Gaps = 16/125 (12%)
Query: 1 MAEAELHKERLQAIAEKRKRQTEIEGKR-QQLDEQILLLQHSKSKVLREKWLLQGIPAGT 59
+ + E+ + LQ K + +I KR +QL+++ L+ S++ ++K L+
Sbjct: 786 LQDLEMENQTLQ----KNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLE------ 835
Query: 60 AEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSF 119
+E + R+Q+E + +++ I LE+E +TL E KE + +LKE EK
Sbjct: 836 -KENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIG--IYKESCV--RLKELEKEN 890
Query: 120 KDFQK 124
K+ K
Sbjct: 891 KELVK 895
Score = 31.2 bits (69), Expect = 5.7
Identities = 28/119 (23%), Positives = 56/119 (47%), Gaps = 5/119 (4%)
Query: 2 AEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAE 61
+E E K+ L+ + K+ +E Q LD + LQ + ++ L+
Sbjct: 732 SEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEM 791
Query: 62 EEEARRRQSEEDEF---RVKQLEDNIQRLEQEIQTLESEESQISAKEQIILE--KLKET 115
E + ++ EE + R++QLE + LEQE LE ++ Q+ + + + + ++K+T
Sbjct: 792 ENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT 850
Score = 30.8 bits (68), Expect = 7.4
Identities = 34/147 (23%), Positives = 62/147 (42%), Gaps = 32/147 (21%)
Query: 8 KERLQAIAEKRKRQTEIEGKRQQLD-----------------EQILLLQHSKSKVLRE-- 48
K+ L+ EK +R E+E + L+ E+I L+ S++ RE
Sbjct: 614 KKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENR 673
Query: 49 --KWLLQGIPAGTAEEEEARRRQSEEDEFRVKQLEDNIQ----------RLEQEIQTLES 96
K L T + E + S+ DE + +L N++ +L+ E + LES
Sbjct: 674 KLKKTLDSFKNLTFQLESLEKENSQLDEENL-ELRRNVESLKCASMKMAQLQLENKELES 732
Query: 97 EESQISAKEQIILEKLKETEKSFKDFQ 123
E+ Q+ +++ K+TE+ +Q
Sbjct: 733 EKEQLKKGLELLKASFKKTERLEVSYQ 759
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.124 0.344
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,808,182
Number of Sequences: 37866
Number of extensions: 2594744
Number of successful extensions: 30418
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 303
Number of HSP's successfully gapped in prelim test: 1011
Number of HSP's that attempted gapping in prelim test: 17145
Number of HSP's gapped (non-prelim): 11048
length of query: 1103
length of database: 18,247,518
effective HSP length: 113
effective length of query: 990
effective length of database: 13,968,660
effective search space: 13828973400
effective search space used: 13828973400
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.