Guide to the Human Genome
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Name: MAP4K4 Sequence: fasta or formatted (1320aa) NCBI GI: 22035604
Description:

mitogen-activated protein kinase kinase kinase kinase 4 isoform 2

Referenced in:

MAP Kinase Pathways

Other entries for this name:
alt prot [1166aa] mitogen-activated protein kinase kinase kinase kinase 4 isoform 1
alt prot [1212aa] mitogen-activated protein kinase kinase kinase kinase 4 isoform 3
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.7         62           2
 C cysteine            1.1         14           1
 D aspartate           4.8         63           3
 E glutamate          10.2        135           6
 F phenylalanine       2.5         33           2
 G glycine             5.5         73           2
 H histidine           3.0         40           3
 I isoleucine          3.8         50           3
 K lysine              6.0         79           2
 L leucine             8.1        107           2
 M methionine          1.7         22           1
 N asparagine          3.0         39           2
 P proline             6.1         81           4
 Q glutamine           6.3         83           3
 R arginine            8.8        116           3
 S serine              9.7        128           4
 T threonine           4.3         57           2
 V valine              6.7         89           2
 W tryptophan          1.2         16           1
 Y tyrosine            2.5         33           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   mitogen-activated protein kinase kinase kinase kinas... 
MAP4K4                0.766   mitogen-activated protein kinase kinase kinase kinas...
TNIK                  0.636   TRAF2 and NCK interacting kinase isoform 2 
TNIK                  0.636   TRAF2 and NCK interacting kinase isoform 1 
TNIK                  0.617   TRAF2 and NCK interacting kinase isoform 6 
TNIK                  0.616   TRAF2 and NCK interacting kinase isoform 5 
TNIK                  0.614   TRAF2 and NCK interacting kinase isoform 4 
TNIK                  0.614   TRAF2 and NCK interacting kinase isoform 3 
TNIK                  0.591   TRAF2 and NCK interacting kinase isoform 8 
TNIK                  0.591   TRAF2 and NCK interacting kinase isoform 7 
MINK1                 0.581   misshapen/NIK-related kinase isoform 3 
MINK1                 0.581   misshapen/NIK-related kinase isoform 1 
MINK1                 0.580   misshapen/NIK-related kinase isoform 2 
MINK1                 0.578   misshapen/NIK-related kinase isoform 4 
MAP4K4                0.473   mitogen-activated protein kinase kinase kinase kinas...
NRK                   0.150   Nik related kinase 
MYO3A                 0.107   myosin IIIA 
MYO3B                 0.103   myosin IIIB isoform 1 
MYO3B                 0.103   myosin IIIB isoform 2 
STK4                  0.093   serine/threonine kinase 4 
MAP4K3                0.092   mitogen-activated protein kinase kinase kinase kinas...
STK3                  0.089   serine/threonine kinase 3 
MAP4K5                0.088   mitogen-activated protein kinase kinase kinase kinas...
MAP4K5                0.088   mitogen-activated protein kinase kinase kinase kinas...
STK25                 0.086   serine/threonine kinase 25 
MST4                  0.085   serine/threonine protein kinase MST4 isoform 1 [Homo...
STK24                 0.083   serine/threonine kinase 24 isoform b 
STK24                 0.083   serine/threonine kinase 24 isoform a 
MAP4K2                0.082   mitogen-activated protein kinase kinase kinase kinas...
SLK                   0.081   serine/threonine kinase 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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