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Search of human proteins with 58533159
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens]
(234 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens] 476 e-135
gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens] 403 e-113
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens] 392 e-109
gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens] 210 7e-55
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens] 200 8e-52
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens] 170 8e-43
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens] 167 7e-42
gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens] 164 5e-41
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 134 7e-32
gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens] 117 8e-27
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 117 8e-27
gi|13994151 PDZ and LIM domain 1 [Homo sapiens] 105 3e-23
gi|196162711 PDZ and LIM domain 4 isoform 2 [Homo sapiens] 91 7e-19
gi|19923181 PDZ and LIM domain 4 isoform 1 [Homo sapiens] 91 7e-19
gi|166235178 PDZ and LIM domain protein 3 isoform b [Homo sapiens] 87 9e-18
gi|166235176 PDZ and LIM domain protein 3 isoform a [Homo sapiens] 87 9e-18
gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens] 86 3e-17
gi|28866957 PDZ and LIM domain 2 isoform 1 [Homo sapiens] 86 3e-17
gi|21361888 PDZ and LIM domain 2 isoform 2 [Homo sapiens] 86 3e-17
gi|193083191 synaptopodin 2 isoform c [Homo sapiens] 65 4e-11
gi|193083185 synaptopodin 2 isoform b [Homo sapiens] 65 4e-11
gi|193083183 synaptopodin 2 isoform a [Homo sapiens] 65 4e-11
gi|166706868 synaptopodin 2-like isoform a [Homo sapiens] 64 1e-10
gi|118600967 shroom family member 4 [Homo sapiens] 60 2e-09
gi|4502175 apical protein of Xenopus-like [Homo sapiens] 54 1e-07
gi|153070254 MAGI family member, X-linked isoform b [Homo sapiens] 52 4e-07
gi|153070258 MAGI family member, X-linked isoform a [Homo sapiens] 52 4e-07
gi|218505835 membrane-associated guanylate kinase-related 3 iso... 51 7e-07
gi|203098098 shroom family member 3 protein [Homo sapiens] 50 1e-06
gi|13376349 PDZ domain containing 7 [Homo sapiens] 50 2e-06
>gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens]
Length = 234
Score = 476 bits (1225), Expect = e-135
Identities = 234/234 (100%), Positives = 234/234 (100%)
Query: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG
Sbjct: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
Query: 61 MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTVTSVCSETSQELAEGQRRGSQ 120
MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTVTSVCSETSQELAEGQRRGSQ
Sbjct: 61 MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTVTSVCSETSQELAEGQRRGSQ 120
Query: 121 GDSKQQNGKIPPKRPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSF 180
GDSKQQNGKIPPKRPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSF
Sbjct: 121 GDSKQQNGKIPPKRPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSF 180
Query: 181 RILAQITGTEHLKESEADNTKKAKEKIPLHVFSPKYTKLRDWHHEVSARALNVQ 234
RILAQITGTEHLKESEADNTKKAKEKIPLHVFSPKYTKLRDWHHEVSARALNVQ
Sbjct: 181 RILAQITGTEHLKESEADNTKKAKEKIPLHVFSPKYTKLRDWHHEVSARALNVQ 234
>gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens]
Length = 214
Score = 403 bits (1036), Expect = e-113
Identities = 205/234 (87%), Positives = 206/234 (88%), Gaps = 20/234 (8%)
Query: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG
Sbjct: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
Query: 61 MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTVTSVCSETSQELAEGQRRGSQ 120
MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQK T Q
Sbjct: 61 MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKKT--------------------Q 100
Query: 121 GDSKQQNGKIPPKRPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSF 180
+ KIPPKRPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSF
Sbjct: 101 VTNNPGTVKIPPKRPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSF 160
Query: 181 RILAQITGTEHLKESEADNTKKAKEKIPLHVFSPKYTKLRDWHHEVSARALNVQ 234
RILAQITGTEHLKESEADNTKKAKEKIPLHVFSPKYTKLRDWHHEVSARALNVQ
Sbjct: 161 RILAQITGTEHLKESEADNTKKAKEKIPLHVFSPKYTKLRDWHHEVSARALNVQ 214
>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
Length = 487
Score = 392 bits (1007), Expect = e-109
Identities = 197/203 (97%), Positives = 197/203 (97%), Gaps = 6/203 (2%)
Query: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG
Sbjct: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
Query: 61 MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTVTSVCSETSQELAEGQRRGSQ 120
MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTVTSVCSETSQELAEGQRRGSQ
Sbjct: 61 MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTVTSVCSETSQELAEGQRRGSQ 120
Query: 121 GDSKQQNGKIPPKRPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSF 180
GDSKQQNG PPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSF
Sbjct: 121 GDSKQQNG------PPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSF 174
Query: 181 RILAQITGTEHLKESEADNTKKA 203
RILAQITGTEHLKESEADNTKKA
Sbjct: 175 RILAQITGTEHLKESEADNTKKA 197
>gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens]
Length = 222
Score = 210 bits (535), Expect = 7e-55
Identities = 122/239 (51%), Positives = 151/239 (63%), Gaps = 23/239 (9%)
Query: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
M ++ V L GPAPWGFRLQGGKDFN+PL+IS L GGKAAQA V +GD VLSIDG NA
Sbjct: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
Query: 61 MTHLEAQNKIKGCTGSLNMTLQRA----SAAPKPEPVPVQKPTVTSVCSETSQELAEGQR 116
+TH+EAQNKI+ C L++ L RA S K P T S + + A
Sbjct: 61 LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120
Query: 117 RGSQGDS-KQQNGKIPPKRPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTT 175
DS QQNG+ P RP VP DASK+RL+E+TEDWRPR GT
Sbjct: 121 APPPADSAPQQNGQ--PLRP-------------LVP---DASKQRLMENTEDWRPRPGTG 162
Query: 176 QSRSFRILAQITGTEHLKESEADNTKKAKEKIPLHVFSPKYTKLRDWHHEVSARALNVQ 234
QSRSFRILA +TGTE +++ + ++ KK++EK L + SP+YT+LRDWHH+ SA LNVQ
Sbjct: 163 QSRSFRILAHLTGTEFMQDPDEEHLKKSREKYVLELQSPRYTRLRDWHHQRSAHVLNVQ 221
>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
Length = 596
Score = 200 bits (509), Expect = 8e-52
Identities = 100/108 (92%), Positives = 102/108 (94%), Gaps = 6/108 (5%)
Query: 96 QKPTVTSVCSETSQELAEGQRRGSQGDSKQQNGKIPPKRPPRKHIVERYTEFYHVPTHSD 155
++PTVTSVCSETSQELAEGQRRGSQGDSKQQNG PPRKHIVERYTEFYHVPTHSD
Sbjct: 205 RQPTVTSVCSETSQELAEGQRRGSQGDSKQQNG------PPRKHIVERYTEFYHVPTHSD 258
Query: 156 ASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNTKKA 203
ASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNTKKA
Sbjct: 259 ASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNTKKA 306
Score = 197 bits (500), Expect = 8e-51
Identities = 97/97 (100%), Positives = 97/97 (100%)
Query: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG
Sbjct: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
Query: 61 MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQK 97
MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQK
Sbjct: 61 MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQK 97
>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
Length = 457
Score = 170 bits (431), Expect = 8e-43
Identities = 103/210 (49%), Positives = 128/210 (60%), Gaps = 23/210 (10%)
Query: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
M ++ V L GPAPWGFRLQGGKDFN+PL+IS L GGKAAQA V +GD VLSIDG NA
Sbjct: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
Query: 61 MTHLEAQNKIKGCTGSLNMTLQRA----SAAPKPEPVPVQKPTVTSVCSETSQELAEGQR 116
+TH+EAQNKI+ C L++ L RA S K P T S + + A
Sbjct: 61 LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120
Query: 117 RGSQGDS-KQQNGKIPPKRPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTT 175
DS QQNG+ P RP VP DASK+RL+E+TEDWRPR GT
Sbjct: 121 APPPADSAPQQNGQ--PLRP-------------LVP---DASKQRLMENTEDWRPRPGTG 162
Query: 176 QSRSFRILAQITGTEHLKESEADNTKKAKE 205
QSRSFRILA +TGTE +++ + ++ KK+ +
Sbjct: 163 QSRSFRILAHLTGTEFMQDPDEEHLKKSSQ 192
>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
Length = 423
Score = 167 bits (423), Expect = 7e-42
Identities = 97/205 (47%), Positives = 121/205 (59%), Gaps = 47/205 (22%)
Query: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
M ++ V L GPAPWGFRLQGGKDFN+PL+IS L GGKAAQA V +GD VLSIDG NA
Sbjct: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
Query: 61 MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTVTSVCSETSQELAEGQRRGSQ 120
+TH+EAQNKI+ C L++ L RA PVQ
Sbjct: 61 LTHIEAQNKIRACGERLSLGLSRAQ--------PVQ------------------------ 88
Query: 121 GDSKQQNGKIPPKRPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSF 180
SK Q + P K+P R P DASK+RL+E+TEDWRPR GT QSRSF
Sbjct: 89 --SKPQKVQTPDKQPLR-------------PLVPDASKQRLMENTEDWRPRPGTGQSRSF 133
Query: 181 RILAQITGTEHLKESEADNTKKAKE 205
RILA +TGTE +++ + ++ KK+ +
Sbjct: 134 RILAHLTGTEFMQDPDEEHLKKSSQ 158
>gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens]
Length = 283
Score = 164 bits (416), Expect = 5e-41
Identities = 101/284 (35%), Positives = 149/284 (52%), Gaps = 55/284 (19%)
Query: 3 NYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMT 62
+YSV+L GP PWGFRLQGGKDFNMPLTIS + G KAAQ+ + GD+V++IDG+N MT
Sbjct: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
Query: 63 HLEAQNKIKGCTGSLNMTLQRA--------SAAPKPEPVPV---QKPTVTSVCSETSQEL 111
HLEAQNKIK + +L++TLQ++ +A P P+PV QK V S + QE
Sbjct: 62 HLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQER 121
Query: 112 ----------------AEGQRRGSQ-------------------------GDSKQQNGKI 130
E + G + G ++ Q
Sbjct: 122 FNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSDF 181
Query: 131 PPKRPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTE 190
P + V+ + Y S + ++ ++W R+ QSRSFRILAQ+TGTE
Sbjct: 182 SGSLPIKDLAVDSASPVYQAVIKSQNKPE---DEADEWARRSSNLQSRSFRILAQMTGTE 238
Query: 191 HLKESEADNTKKAKEKIPLHVFSPKYTKLRDWHHEVSARALNVQ 234
+++ + + ++++E+ SP++ KLR+WHH +SA+ LNV+
Sbjct: 239 FMQDPDEEALRRSRERFETERNSPRFAKLRNWHHGLSAQILNVK 282
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 134 bits (337), Expect = 7e-32
Identities = 87/254 (34%), Positives = 128/254 (50%), Gaps = 55/254 (21%)
Query: 3 NYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMT 62
+YSV+L GP PWGFRLQGGKDFNMPLTIS + G KAAQ+ + GD+V++IDG+N MT
Sbjct: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
Query: 63 HLEAQNKIKGCTGSLNMTLQRA--------SAAPKPEPVPV---QKPTVTSVCSETSQEL 111
HLEAQNKIK + +L++TLQ++ +A P P+PV QK V S + QE
Sbjct: 62 HLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQER 121
Query: 112 ----------------AEGQRRGSQ-------------------------GDSKQQNGKI 130
E + G + G ++ Q
Sbjct: 122 FNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSDF 181
Query: 131 PPKRPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTE 190
P + V+ + Y S + ++ ++W R+ QSRSFRILAQ+TGTE
Sbjct: 182 SGSLPIKDLAVDSASPVYQAVIKSQNKPE---DEADEWARRSSNLQSRSFRILAQMTGTE 238
Query: 191 HLKESEADNTKKAK 204
+++ + + ++++
Sbjct: 239 FMQDPDEEALRRSR 252
>gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens]
Length = 330
Score = 117 bits (293), Expect = 8e-27
Identities = 56/98 (57%), Positives = 73/98 (74%), Gaps = 3/98 (3%)
Query: 3 NYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMT 62
+YSV+L GP PWGFRLQGGKDFNMPLTIS + G KAAQ+ + GD+V++IDG+N MT
Sbjct: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
Query: 63 HLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTV 100
HLEAQNKIK + +L++TLQ++ +P P+ P V
Sbjct: 62 HLEAQNKIKSASYNLSLTLQKSK---RPIPISTTAPPV 96
Score = 73.9 bits (180), Expect = 1e-13
Identities = 42/131 (32%), Positives = 75/131 (57%), Gaps = 6/131 (4%)
Query: 105 SETSQELAEGQRRGSQGDSKQQNGKIPPKRPPRKHI-VERYTEFYHVPTHSDASKKRLIE 163
+ET +E+A+ + +G K +P P K + V+ + Y S + +
Sbjct: 204 AETLREMAQMYQMSLRG--KASGVGLPGGSLPIKDLAVDSASPVYQAVIKSQNKPE---D 258
Query: 164 DTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNTKKAKEKIPLHVFSPKYTKLRDWH 223
+ ++W R+ QSRSFRILAQ+TGTE +++ + + ++++E+ SP++ KLR+WH
Sbjct: 259 EADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSRERFETERNSPRFAKLRNWH 318
Query: 224 HEVSARALNVQ 234
H +SA+ LNV+
Sbjct: 319 HGLSAQILNVK 329
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 117 bits (293), Expect = 8e-27
Identities = 56/98 (57%), Positives = 73/98 (74%), Gaps = 3/98 (3%)
Query: 3 NYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMT 62
+YSV+L GP PWGFRLQGGKDFNMPLTIS + G KAAQ+ + GD+V++IDG+N MT
Sbjct: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
Query: 63 HLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTV 100
HLEAQNKIK + +L++TLQ++ +P P+ P V
Sbjct: 62 HLEAQNKIKSASYNLSLTLQKSK---RPIPISTTAPPV 96
Score = 43.5 bits (101), Expect = 2e-04
Identities = 29/104 (27%), Positives = 54/104 (51%), Gaps = 6/104 (5%)
Query: 105 SETSQELAEGQRRGSQGDSKQQNGKIPPKRPPRKHI-VERYTEFYHVPTHSDASKKRLIE 163
+ET +E+A+ + +G K +P P K + V+ + Y S + +
Sbjct: 204 AETLREMAQMYQMSLRG--KASGVGLPGGSLPIKDLAVDSASPVYQAVIKSQNKPE---D 258
Query: 164 DTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNTKKAKEKI 207
+ ++W R+ QSRSFRILAQ+TGTE +++ + + +++ I
Sbjct: 259 EADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSSTPI 302
>gi|13994151 PDZ and LIM domain 1 [Homo sapiens]
Length = 329
Score = 105 bits (263), Expect = 3e-23
Identities = 49/84 (58%), Positives = 60/84 (71%)
Query: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
M+ + L GP PWGFRL GGKDF PL IS + G KAA AN+ IGDV+ +IDG N
Sbjct: 1 MTTQQIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSN 60
Query: 61 MTHLEAQNKIKGCTGSLNMTLQRA 84
MTHLEAQN+IKGCT +L +T+ R+
Sbjct: 61 MTHLEAQNRIKGCTDNLTLTVARS 84
>gi|196162711 PDZ and LIM domain 4 isoform 2 [Homo sapiens]
Length = 246
Score = 91.3 bits (225), Expect = 7e-19
Identities = 55/142 (38%), Positives = 80/142 (56%), Gaps = 10/142 (7%)
Query: 4 YSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTH 63
+SV+L GP+PWGFRL GG+DF+ PLTIS + G KAA A + GD++ +I+G + + MTH
Sbjct: 3 HSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTH 62
Query: 64 LEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTVTSVCSETSQELAEG----QRRGS 119
LEAQN+IKGC L +++ R P K + E+ +G RR S
Sbjct: 63 LEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRI--HIDPEIQDGSPTTSRRPS 120
Query: 120 QGDSKQQNGK----IPPKRPPR 137
+ ++G+ P +PPR
Sbjct: 121 GTGTGPEDGRPSLGSPYGQPPR 142
>gi|19923181 PDZ and LIM domain 4 isoform 1 [Homo sapiens]
Length = 330
Score = 91.3 bits (225), Expect = 7e-19
Identities = 55/142 (38%), Positives = 80/142 (56%), Gaps = 10/142 (7%)
Query: 4 YSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTH 63
+SV+L GP+PWGFRL GG+DF+ PLTIS + G KAA A + GD++ +I+G + + MTH
Sbjct: 3 HSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTH 62
Query: 64 LEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTVTSVCSETSQELAEG----QRRGS 119
LEAQN+IKGC L +++ R P K + E+ +G RR S
Sbjct: 63 LEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRI--HIDPEIQDGSPTTSRRPS 120
Query: 120 QGDSKQQNGK----IPPKRPPR 137
+ ++G+ P +PPR
Sbjct: 121 GTGTGPEDGRPSLGSPYGQPPR 142
>gi|166235178 PDZ and LIM domain protein 3 isoform b [Homo
sapiens]
Length = 316
Score = 87.4 bits (215), Expect = 9e-18
Identities = 41/79 (51%), Positives = 53/79 (67%)
Query: 5 SVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHL 64
+V L GPAPWGFRL GG DFN PL I+ + G KAA AN+ GDV+L+IDG + MTH
Sbjct: 4 TVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHA 63
Query: 65 EAQNKIKGCTGSLNMTLQR 83
+AQ++IK L + + R
Sbjct: 64 DAQDRIKAAAHQLCLKIDR 82
>gi|166235176 PDZ and LIM domain protein 3 isoform a [Homo
sapiens]
Length = 364
Score = 87.4 bits (215), Expect = 9e-18
Identities = 41/79 (51%), Positives = 53/79 (67%)
Query: 5 SVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHL 64
+V L GPAPWGFRL GG DFN PL I+ + G KAA AN+ GDV+L+IDG + MTH
Sbjct: 4 TVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHA 63
Query: 65 EAQNKIKGCTGSLNMTLQR 83
+AQ++IK L + + R
Sbjct: 64 DAQDRIKAAAHQLCLKIDR 82
>gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens]
Length = 278
Score = 85.9 bits (211), Expect = 3e-17
Identities = 36/82 (43%), Positives = 59/82 (71%)
Query: 5 SVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHL 64
+V + GPAPWGFR+ GG+DF+ P+ ++ + + GKA A++R GD++++I+G +A+GM H
Sbjct: 4 TVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGMLHA 63
Query: 65 EAQNKIKGCTGSLNMTLQRASA 86
EAQ+KI+ L + L R+ A
Sbjct: 64 EAQSKIRQSPSPLRLQLDRSQA 85
>gi|28866957 PDZ and LIM domain 2 isoform 1 [Homo sapiens]
Length = 366
Score = 85.9 bits (211), Expect = 3e-17
Identities = 36/82 (43%), Positives = 59/82 (71%)
Query: 5 SVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHL 64
+V + GPAPWGFR+ GG+DF+ P+ ++ + + GKA A++R GD++++I+G +A+GM H
Sbjct: 4 TVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGMLHA 63
Query: 65 EAQNKIKGCTGSLNMTLQRASA 86
EAQ+KI+ L + L R+ A
Sbjct: 64 EAQSKIRQSPSPLRLQLDRSQA 85
>gi|21361888 PDZ and LIM domain 2 isoform 2 [Homo sapiens]
Length = 352
Score = 85.9 bits (211), Expect = 3e-17
Identities = 36/82 (43%), Positives = 59/82 (71%)
Query: 5 SVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHL 64
+V + GPAPWGFR+ GG+DF+ P+ ++ + + GKA A++R GD++++I+G +A+GM H
Sbjct: 4 TVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGMLHA 63
Query: 65 EAQNKIKGCTGSLNMTLQRASA 86
EAQ+KI+ L + L R+ A
Sbjct: 64 EAQSKIRQSPSPLRLQLDRSQA 85
>gi|193083191 synaptopodin 2 isoform c [Homo sapiens]
Length = 1109
Score = 65.5 bits (158), Expect = 4e-11
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 30/160 (18%)
Query: 6 VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLE 65
+S+ G APWGFRLQGGK+ PL ++ +++ KA+ + + GD V+SI+G +T+ E
Sbjct: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
Query: 66 AQNKIKGCTGSLNMTLQRASAAPKP--------------------EPVPVQ-KPTVTSVC 104
++ T SL M ++R S+ E +Q +P + C
Sbjct: 69 VIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQC 128
Query: 105 SE-------TSQELAEGQRRGSQ--GDSKQQNGKIPPKRP 135
+E T LAE QR G G K++ G + P
Sbjct: 129 TEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAP 168
>gi|193083185 synaptopodin 2 isoform b [Homo sapiens]
Length = 1093
Score = 65.5 bits (158), Expect = 4e-11
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 30/160 (18%)
Query: 6 VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLE 65
+S+ G APWGFRLQGGK+ PL ++ +++ KA+ + + GD V+SI+G +T+ E
Sbjct: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
Query: 66 AQNKIKGCTGSLNMTLQRASAAPKP--------------------EPVPVQ-KPTVTSVC 104
++ T SL M ++R S+ E +Q +P + C
Sbjct: 69 VIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQC 128
Query: 105 SE-------TSQELAEGQRRGSQ--GDSKQQNGKIPPKRP 135
+E T LAE QR G G K++ G + P
Sbjct: 129 TEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAP 168
>gi|193083183 synaptopodin 2 isoform a [Homo sapiens]
Length = 1261
Score = 65.5 bits (158), Expect = 4e-11
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 30/160 (18%)
Query: 6 VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLE 65
+S+ G APWGFRLQGGK+ PL ++ +++ KA+ + + GD V+SI+G +T+ E
Sbjct: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
Query: 66 AQNKIKGCTGSLNMTLQRASAAPKP--------------------EPVPVQ-KPTVTSVC 104
++ T SL M ++R S+ E +Q +P + C
Sbjct: 69 VIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQC 128
Query: 105 SE-------TSQELAEGQRRGSQ--GDSKQQNGKIPPKRP 135
+E T LAE QR G G K++ G + P
Sbjct: 129 TEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAP 168
>gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]
Length = 977
Score = 63.9 bits (154), Expect = 1e-10
Identities = 33/90 (36%), Positives = 51/90 (56%), Gaps = 1/90 (1%)
Query: 6 VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLE 65
V+L G APWGFRL GG + PL +S ++ +A +A +R D +L+I+G++ ++H
Sbjct: 9 VTLSGGAPWGFRLHGGAEQRKPLQVSKIRRRSQAGRAGLRERDQLLAINGVSCTNLSHAS 68
Query: 66 AQNKIKGCTGSLNMTLQR-ASAAPKPEPVP 94
A + I L +T+QR A P P P
Sbjct: 69 AMSLIDASGNQLVLTVQRLADEGPVQSPSP 98
>gi|118600967 shroom family member 4 [Homo sapiens]
Length = 1493
Score = 59.7 bits (143), Expect = 2e-09
Identities = 38/94 (40%), Positives = 54/94 (57%), Gaps = 9/94 (9%)
Query: 6 VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAA-QANVRIGDVVLSIDGINAQGMTHL 64
V L G APWGF L+GG + PLT+S ++DGGKAA +R GD +++I+G G +
Sbjct: 13 VQLQGGAPWGFTLKGGLEHCEPLTVSKIEDGGKAALSQKMRTGDELVNINGTPLYG-SRQ 71
Query: 65 EAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKP 98
EA IKG L + ++R +A PV +P
Sbjct: 72 EALILIKGSFRILKLIVRRRNA-------PVSRP 98
>gi|4502175 apical protein of Xenopus-like [Homo sapiens]
Length = 1616
Score = 53.9 bits (128), Expect = 1e-07
Identities = 30/81 (37%), Positives = 47/81 (58%), Gaps = 2/81 (2%)
Query: 6 VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQAN-VRIGDVVLSIDGINAQGMTHL 64
V L G APWGF L+GG++ PL I+ +++G KAA + + GD ++ I+ I G
Sbjct: 29 VQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQ- 87
Query: 65 EAQNKIKGCTGSLNMTLQRAS 85
EA +KG +L + ++R S
Sbjct: 88 EAICLVKGSHKTLKLVVKRRS 108
>gi|153070254 MAGI family member, X-linked isoform b [Homo sapiens]
Length = 262
Score = 52.0 bits (123), Expect = 4e-07
Identities = 34/100 (34%), Positives = 55/100 (55%), Gaps = 4/100 (4%)
Query: 3 NYSVSLV-GPAPWGFRLQGGKDF--NMPLTISSL-KDGGKAAQANVRIGDVVLSIDGINA 58
++SV LV G A +G L GG+D + PL + L KDG + +GD+VL I+G +
Sbjct: 56 HFSVELVRGYAGFGLTLGGGRDVAGDTPLAVRGLLKDGPAQRCGRLEVGDLVLHINGEST 115
Query: 59 QGMTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKP 98
QG+TH +A +I+ L++ ++R +P V +P
Sbjct: 116 QGLTHAQAVERIRAGGPQLHLVIRRPLETHPGKPRGVGEP 155
>gi|153070258 MAGI family member, X-linked isoform a [Homo sapiens]
Length = 334
Score = 52.0 bits (123), Expect = 4e-07
Identities = 34/100 (34%), Positives = 55/100 (55%), Gaps = 4/100 (4%)
Query: 3 NYSVSLV-GPAPWGFRLQGGKDF--NMPLTISSL-KDGGKAAQANVRIGDVVLSIDGINA 58
++SV LV G A +G L GG+D + PL + L KDG + +GD+VL I+G +
Sbjct: 123 HFSVELVRGYAGFGLTLGGGRDVAGDTPLAVRGLLKDGPAQRCGRLEVGDLVLHINGEST 182
Query: 59 QGMTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKP 98
QG+TH +A +I+ L++ ++R +P V +P
Sbjct: 183 QGLTHAQAVERIRAGGPQLHLVIRRPLETHPGKPRGVGEP 222
>gi|218505835 membrane-associated guanylate kinase-related 3 isoform
1 [Homo sapiens]
Length = 1481
Score = 51.2 bits (121), Expect = 7e-07
Identities = 39/160 (24%), Positives = 68/160 (42%), Gaps = 26/160 (16%)
Query: 10 GPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQ-ANVRIGDVVLSIDGINAQGMTHLEAQN 68
GP +GF L+GGK++NM L I L + G A + + +GD ++ I+G QG+TH A
Sbjct: 1027 GPRGFGFSLRGGKEYNMGLFILRLAEDGPAIKDGRIHVGDQIVEINGEPTQGITHTRAIE 1086
Query: 69 KIKGCTGSLNMTLQRASA-APKPEPVPVQKPTVTSVCSETSQELAEGQRRGSQGDSKQQN 127
I+ + + L+ + P + P+ ++V + L
Sbjct: 1087 LIQAGGNKVLLLLRPGTGLIPDHGDWDINNPSSSNVIYDEQSPL---------------- 1130
Query: 128 GKIPPKRPPRKHIVERYTEFYHVPTHSDASKKRLIEDTED 167
PP H + E HVP ++ + ++ E E+
Sbjct: 1131 -------PPSSHFASIFEE-SHVPVIEESLRVQICEKAEE 1162
Score = 35.4 bits (80), Expect = 0.042
Identities = 35/125 (28%), Positives = 54/125 (43%), Gaps = 10/125 (8%)
Query: 14 WGFRLQGGKDFNMPLTISS-LKDGGKAAQANVRIGDVVLSIDGINAQGMTHLEAQN--KI 70
+GF + GG + L + + LKDG A + GDV++ I+G G TH + ++
Sbjct: 420 FGFTIIGGDRPDEFLQVKNVLKDGPAAQDGKIAPGDVIVDINGNCVLGHTHADVVQMFQL 479
Query: 71 KGCTGSLNMTLQRASAAPKPEPVPVQKPTVTSVCSETSQELAEGQRRGSQGDSK------ 124
+N+TL R P PV V + Q L +G+ + D K
Sbjct: 480 VPVNQYVNLTLCRGYPLPDDSEDPV-VDIVAATPVINGQSLTKGETCMNPQDFKPGAMVL 538
Query: 125 QQNGK 129
+QNGK
Sbjct: 539 EQNGK 543
>gi|203098098 shroom family member 3 protein [Homo sapiens]
Length = 1996
Score = 50.4 bits (119), Expect = 1e-06
Identities = 28/78 (35%), Positives = 46/78 (58%), Gaps = 3/78 (3%)
Query: 8 LVGPAPWGFRLQGGKDFNMPLTISSLKDGGKA--AQANVRIGDVVLSIDGINAQGMTHLE 65
L G APWGF L+GG + PL IS +++GGKA + ++ GD V+ I+ + + E
Sbjct: 32 LEGGAPWGFTLKGGLEHGEPLIISKVEEGGKADTLSSKLQAGDEVVHINEVTLSS-SRKE 90
Query: 66 AQNKIKGCTGSLNMTLQR 83
A + +KG +L + ++R
Sbjct: 91 AVSLVKGSYKTLRLVVRR 108
>gi|13376349 PDZ domain containing 7 [Homo sapiens]
Length = 517
Score = 50.1 bits (118), Expect = 2e-06
Identities = 22/74 (29%), Positives = 44/74 (59%), Gaps = 1/74 (1%)
Query: 15 GFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLEAQNKIKGCT 74
GF ++GGK+F + + +S + GG A + +++GD VL+ +G+ ++H +A +KG T
Sbjct: 223 GFNIRGGKEFGLGIYVSKVDHGGLAEENGIKVGDQVLAANGVRFDDISHSQAVEVLKGQT 282
Query: 75 GSLNMTLQRASAAP 88
+ +T++ P
Sbjct: 283 -HIMLTIKETGRYP 295
Score = 39.7 bits (91), Expect = 0.002
Identities = 17/74 (22%), Positives = 42/74 (56%), Gaps = 1/74 (1%)
Query: 15 GFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLEAQNKIKGCT 74
GF ++GG + + + +S +++G A +A + +GD + ++G++ + T + + K+ +
Sbjct: 98 GFSVRGGSEHGLGIFVSKVEEGSSAERAGLCVGDKITEVNGLSLESTT-MGSAVKVLTSS 156
Query: 75 GSLNMTLQRASAAP 88
L+M ++R P
Sbjct: 157 SRLHMMVRRMGRVP 170
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,515,325
Number of Sequences: 37866
Number of extensions: 442114
Number of successful extensions: 1964
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 120
Number of HSP's successfully gapped in prelim test: 65
Number of HSP's that attempted gapping in prelim test: 1723
Number of HSP's gapped (non-prelim): 287
length of query: 234
length of database: 18,247,518
effective HSP length: 99
effective length of query: 135
effective length of database: 14,498,784
effective search space: 1957335840
effective search space used: 1957335840
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.