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Search of human proteins with 54792146
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54792146 tripartite motif-containing 47 [Homo sapiens]
(638 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54792146 tripartite motif-containing 47 [Homo sapiens] 1312 0.0
gi|68160937 tripartite motif-containing 25 [Homo sapiens] 187 2e-47
gi|48255913 tripartite motif-containing 16 [Homo sapiens] 173 4e-43
gi|17402909 tripartite motif protein TRIM29 [Homo sapiens] 113 6e-25
gi|148596968 tripartite motif-containing 8 [Homo sapiens] 96 1e-19
gi|30794216 tripartite motif-containing 56 [Homo sapiens] 95 2e-19
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens] 95 2e-19
gi|82617564 tripartite motif-containing 16-like [Homo sapiens] 94 5e-19
gi|38679905 tripartite motif-containing 65 [Homo sapiens] 91 2e-18
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] 83 7e-16
gi|239751227 PREDICTED: hypothetical protein XP_002347761 [Homo ... 83 9e-16
gi|47174859 tripartite motif-containing 46 [Homo sapiens] 81 3e-15
gi|21630277 tripartite motif-containing 11 [Homo sapiens] 78 3e-14
gi|148833499 midline 1 [Homo sapiens] 76 1e-13
gi|4557753 midline 1 [Homo sapiens] 76 1e-13
gi|15451852 midline 1 [Homo sapiens] 76 1e-13
gi|223890259 midline 2 isoform 2 [Homo sapiens] 73 9e-13
gi|223890257 midline 2 isoform 1 [Homo sapiens] 73 9e-13
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] 72 2e-12
gi|16076875 tripartite motif-containing 7 isoform 4 [Homo sapiens] 72 2e-12
gi|112421127 tripartite motif-containing 58 [Homo sapiens] 72 2e-12
gi|5730009 ret finger protein [Homo sapiens] 71 3e-12
gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo ... 70 5e-12
gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo ... 70 5e-12
gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo ... 70 5e-12
gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens] 69 1e-11
gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens] 69 1e-11
gi|84993742 tripartite motif-containing 71 [Homo sapiens] 68 2e-11
gi|56605981 tripartite motif-containing 72 [Homo sapiens] 65 2e-10
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi... 61 3e-09
>gi|54792146 tripartite motif-containing 47 [Homo sapiens]
Length = 638
Score = 1312 bits (3396), Expect = 0.0
Identities = 638/638 (100%), Positives = 638/638 (100%)
Query: 1 MDGSGPFSCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLCQEP 60
MDGSGPFSCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLCQEP
Sbjct: 1 MDGSGPFSCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLCQEP 60
Query: 61 FPDGLQLRKNHTLSELLQLRQGSGPGSGPGPAPALAPEPSAPSALPSVPEPSAPCAPEPW 120
FPDGLQLRKNHTLSELLQLRQGSGPGSGPGPAPALAPEPSAPSALPSVPEPSAPCAPEPW
Sbjct: 61 FPDGLQLRKNHTLSELLQLRQGSGPGSGPGPAPALAPEPSAPSALPSVPEPSAPCAPEPW 120
Query: 121 PAGEEPVRCDACPEGAALPAALSCLSCLASFCPAHLGPHERSPALRGHRLVPPLRRLEES 180
PAGEEPVRCDACPEGAALPAALSCLSCLASFCPAHLGPHERSPALRGHRLVPPLRRLEES
Sbjct: 121 PAGEEPVRCDACPEGAALPAALSCLSCLASFCPAHLGPHERSPALRGHRLVPPLRRLEES 180
Query: 181 LCPRHLRPLERYCRAERVCLCEACAAQEHRGHELVPLEQERALQEAEQSKVLSAVEDRMD 240
LCPRHLRPLERYCRAERVCLCEACAAQEHRGHELVPLEQERALQEAEQSKVLSAVEDRMD
Sbjct: 181 LCPRHLRPLERYCRAERVCLCEACAAQEHRGHELVPLEQERALQEAEQSKVLSAVEDRMD 240
Query: 241 ELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAMLGRS 300
ELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAMLGRS
Sbjct: 241 ELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAMLGRS 300
Query: 301 QGDLRRQEEQRSRLSRARQNLSQVPEADSVSFLQELLALRLALEDGCGPGPGPPRELSFT 360
QGDLRRQEEQRSRLSRARQNLSQVPEADSVSFLQELLALRLALEDGCGPGPGPPRELSFT
Sbjct: 301 QGDLRRQEEQRSRLSRARQNLSQVPEADSVSFLQELLALRLALEDGCGPGPGPPRELSFT 360
Query: 361 KSSQAVRAVRDMLAVACVNQWEQLRGPGGNEDGPQKLDSEADAEPQDLESTNLLESEAPR 420
KSSQAVRAVRDMLAVACVNQWEQLRGPGGNEDGPQKLDSEADAEPQDLESTNLLESEAPR
Sbjct: 361 KSSQAVRAVRDMLAVACVNQWEQLRGPGGNEDGPQKLDSEADAEPQDLESTNLLESEAPR 420
Query: 421 DYFLKFAYIVDLDSDTADKFLQLFGTKGVKRVLCPINYPLSPTRFTHCEQVLGEGALDRG 480
DYFLKFAYIVDLDSDTADKFLQLFGTKGVKRVLCPINYPLSPTRFTHCEQVLGEGALDRG
Sbjct: 421 DYFLKFAYIVDLDSDTADKFLQLFGTKGVKRVLCPINYPLSPTRFTHCEQVLGEGALDRG 480
Query: 481 TYYWEVEIIEGWVSMGVMAEDFSPQEPYDRGRLGRNAHSCCLQWNGRSFSVWFHGLEAPL 540
TYYWEVEIIEGWVSMGVMAEDFSPQEPYDRGRLGRNAHSCCLQWNGRSFSVWFHGLEAPL
Sbjct: 481 TYYWEVEIIEGWVSMGVMAEDFSPQEPYDRGRLGRNAHSCCLQWNGRSFSVWFHGLEAPL 540
Query: 541 PHPFSPTVGVCLEYADRALAFYAVRDGKMSLLRRLKASRPRRGGIPASPIDPFQSRLDSH 600
PHPFSPTVGVCLEYADRALAFYAVRDGKMSLLRRLKASRPRRGGIPASPIDPFQSRLDSH
Sbjct: 541 PHPFSPTVGVCLEYADRALAFYAVRDGKMSLLRRLKASRPRRGGIPASPIDPFQSRLDSH 600
Query: 601 FAGLFTHRLKPAFFLESVDAHLQIGPLKKSCISVLKRR 638
FAGLFTHRLKPAFFLESVDAHLQIGPLKKSCISVLKRR
Sbjct: 601 FAGLFTHRLKPAFFLESVDAHLQIGPLKKSCISVLKRR 638
>gi|68160937 tripartite motif-containing 25 [Homo sapiens]
Length = 630
Score = 187 bits (476), Expect = 2e-47
Identities = 186/675 (27%), Positives = 275/675 (40%), Gaps = 118/675 (17%)
Query: 8 SCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLCQEPFPDGLQL 67
SC ICLEP +EPVT PCGHNFC +CL W +G+ CP C+ + QL
Sbjct: 12 SCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYL--------CPQCRAVYQARPQL 63
Query: 68 RKNHTLSELL-QLRQGSGPGSGPGPAPALAPEPSAPSALPSVPEPSAPCAPEPWPAGEEP 126
KN L ++ Q Q LA EP A P P+ AP P
Sbjct: 64 HKNTVLCNVVEQFLQAD-----------LAREPPADVWTP----PARASAPSP----NAQ 104
Query: 127 VRCDACPEGAALPAALSCLSCLASFCPAHLGPHERSPALRGHRLVPPLRRLEESLCPRHL 186
V CD C + AA+ +CL C+ASFC HL PH SPA + H L PP+R L C +H
Sbjct: 105 VACDHCLKEAAVK---TCLVCMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHN 161
Query: 187 RPLERYCRAERVCLCEACAAQEHRGHELVPLEQERALQEAEQSKVLSAVEDRMDELGAGI 246
R E +C C+C C EH+ L Q A EA L+ + +++ +
Sbjct: 162 RLREFFCPEHSECICHICLV-EHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRAL 220
Query: 247 AQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAMLGRSQGDLRR 306
R ++ A + E++ + + + A L +T I+E E + + +
Sbjct: 221 DDVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQI 280
Query: 307 QEEQRSRLSRARQNLSQ-VPEADSVSFL------------------------------QE 335
+++S + ++ + Q + + D FL Q
Sbjct: 281 LLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQS 340
Query: 336 LLALRLALEDGCG------PGPGPPRELSFTKSSQAVRAVRDML-----------AVACV 378
+ L+ L+ G P G P E + ++ R V+ + A
Sbjct: 341 TIDLKNELKQCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALP 400
Query: 379 NQWEQLRGPGGNEDGPQK-LDSEADAEPQDLESTNL----LES--EAPRDYFLKFAYIVD 431
++ P D Q L++ A A ST+L LE+ R L++ V
Sbjct: 401 SKLPTFGAPEQLVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPELLEYYIKVI 460
Query: 432 LDSDTADKFLQLFGTKGVKRVL-CPINYPLSPTRFTHCEQVLGEGALDRGTYYWEVEIIE 490
LD +TA + L V V P NY P RFT+C QVLG +G +YWEVE+ +
Sbjct: 461 LDYNTAHNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQK 520
Query: 491 G-WVSMGVMAEDFSPQEPYDRGRLGRNAHSCCLQWNGRSFSVWFHGLEAPLPHPFSPTVG 549
+ +G+ + Q P RLGRN+ S C++W S W + +E LP + VG
Sbjct: 521 NNFCGVGICYGSMNRQGP--ESRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVG 578
Query: 550 VCLEYADRALAFYAVRDGKMSLLRRLKASRPRRGGIPASPIDPFQSRLDSHFAGLFTHRL 609
V L + F+AV D K+ L+ ++ R+D FT L
Sbjct: 579 VLLNCDHGFVIFFAVAD-KVHLM--------------------YKFRVD------FTEAL 611
Query: 610 KPAFFLESVDAHLQI 624
PAF++ S A L I
Sbjct: 612 YPAFWVFSAGATLSI 626
>gi|48255913 tripartite motif-containing 16 [Homo sapiens]
Length = 564
Score = 173 bits (439), Expect = 4e-43
Identities = 147/543 (27%), Positives = 238/543 (43%), Gaps = 73/543 (13%)
Query: 89 PGPAPALAPEPSAP-------------SALP--------------SVPEPSAPCAPEPWP 121
PGP P +P AP SA P E + A + P
Sbjct: 9 PGPLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGSSEKLGRETEEQDSDSAEQGDP 68
Query: 122 AGE-EPVRCDACPEGAA-LPAALSCLSCLASFCPAHLGPHERSPALRGHRLVPPLRRLEE 179
AGE + V CD C + + A SCL+C+ ++C HL PH+ + L+ H L P++
Sbjct: 69 AGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLTEPVKDHNW 128
Query: 180 SLCPRHLRPLERYCRAERVCLCEACAAQEHRGHELVPLEQERALQEAE-------QSKVL 232
CP H PL +C ++ C+C+ C QEH GH +V L+ R +EAE + L
Sbjct: 129 RYCPAHHSPLSAFCCPDQQCICQDC-CQEHSGHTIVSLDAARRDKEAELQCTQLDLERKL 187
Query: 233 SAVEDRMDELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEG 292
E+ + L A Q V++ + AVAE + F + AA++ Q V+ F+EE
Sbjct: 188 KLNENAISRLQAN--QKSVLVSVSEVKAVAEMQ-----FGELLAAVRKAQANVMLFLEEK 240
Query: 293 EAAMLGRSQGDLRRQEEQRSRLSRARQNLSQVPE-ADSVSFLQELLALRLALEDGCGPGP 351
E A L ++ G E + + + +++Q L ++ +++V FL+E + ED P
Sbjct: 241 EQAALSQANGIKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFK-NTEDITFPS- 298
Query: 352 GPPRELSFTKSSQAVRAVRDMLAVACVNQWEQLRGPGGNEDGPQKLDSEADAEPQDLEST 411
+ + +R ++ + V+ + L E+ +KL + E D+ +
Sbjct: 299 ------VYVGLKDKLSGIRKVITESTVHLIQLL------ENYKKKLQEFSKEEEYDIRTQ 346
Query: 412 ----------NLLESEAPRDYFLKFAYIVDLDSDTADKFLQL--FGTKGVKRVLCPINYP 459
+ R+ FL++AY + D DTA K+L+L K YP
Sbjct: 347 VSAVVQRKYWTSKPEPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYP 406
Query: 460 LSPTRFTHCEQVLGEGALDRGTYYWEVEIIEGWVSMGVMAEDFSPQEPYDRGRLGRNAHS 519
P+RF H QVL + +L YY+EVEI +G+ + + + N S
Sbjct: 407 DLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISGNNFS 466
Query: 520 CCLQWNGRSFSVWFHGLEAPLPHPFSPTVGVCLEYADRALAFYAVRDGKMSLLRRL--KA 577
LQWNG+ F+ W+ +E PL +GV +++ L+FY V M+L+ + K
Sbjct: 467 WSLQWNGKEFTAWYSDMETPLKAGPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKF 526
Query: 578 SRP 580
S P
Sbjct: 527 SEP 529
>gi|17402909 tripartite motif protein TRIM29 [Homo sapiens]
Length = 588
Score = 113 bits (282), Expect = 6e-25
Identities = 69/219 (31%), Positives = 111/219 (50%), Gaps = 2/219 (0%)
Query: 122 AGEEPVRCDACPEGAALPAALSCLSCLASFCPAHLGPHERSPALRGHRLVPPLRRLEESL 181
+G E V CD+C G A SCL C ASFC HL PH A R H+L+ P+R E
Sbjct: 166 SGSEEVLCDSCI-GNKQKAVKSCLVCQASFCELHLKPHLEGAAFRDHQLLEPIRDFEARK 224
Query: 182 CPRHLRPLERYCRAERVCLCEACAAQEHRGHELVPLEQERALQEAEQSKVLSAVEDRMDE 241
CP H + +E +C+ ++ C+C C QEH+ H V +E+ +A +E E S ++ ++ E
Sbjct: 225 CPVHGKTMELFCQTDQTCICYLCMFQEHKNHSTVTVEEAKAEKETELSLQKEQLQLKIIE 284
Query: 242 LGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAMLGRSQ 301
+ + ++ IKS E+ + + F D L+ + +V +E+ E + + +
Sbjct: 285 IEDEAEKWQKEKDRIKSFTTNEKAILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQVK 344
Query: 302 GDLRRQEEQRSRLSRARQNLSQVPE-ADSVSFLQELLAL 339
+ +E+ L +Q Q+ +DSV FLQE AL
Sbjct: 345 VIMDALDERAKVLHEDKQTREQLHSISDSVLFLQEFGAL 383
>gi|148596968 tripartite motif-containing 8 [Homo sapiens]
Length = 551
Score = 95.9 bits (237), Expect = 1e-19
Identities = 69/236 (29%), Positives = 99/236 (41%), Gaps = 51/236 (21%)
Query: 9 CPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLCQEPFPDGLQLR 68
CPICL EPV LPC HNFC C+G W G RCP C + + L
Sbjct: 15 CPICLHVFVEPVQLPCKHNFCRGCIGEAW--------AKDSGLVRCPECNQAYNQKPGLE 66
Query: 69 KNHTLSELLQLRQGSGPGSGPGPAPALAPEPSAPSALPSVPEPSAPCAPEPWPAGEEPVR 128
KN L+ +++ +AL P+A +
Sbjct: 67 KNLKLTNIVE----------------------KFNALHVEKPPAA-------------LH 91
Query: 129 CDACPEGAALPAALSCLSCLASFCPAHLGPHERSPA-LRGHRLVPPLRRLEESLCPRHLR 187
C C G LPA CL C A C +H+ H + P+ RGH LV + CP+H
Sbjct: 92 CVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPSTARGHLLV-EADDVRAWSCPQHNA 150
Query: 188 PLERYCRAERVCLCEACA--AQEHRGHELVPLEQERALQEAEQSKVLSAVEDRMDE 241
+C AE+V +C+ C + H+GH + +E ++ E K+L +DR++E
Sbjct: 151 YRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVE----IRRNEIRKMLMKQQDRLEE 202
>gi|30794216 tripartite motif-containing 56 [Homo sapiens]
Length = 755
Score = 95.1 bits (235), Expect = 2e-19
Identities = 96/366 (26%), Positives = 137/366 (37%), Gaps = 61/366 (16%)
Query: 8 SCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLCQEPF---PDG 64
+C ICLE LR P TLPC H +C CL L GG RCP C+E P+G
Sbjct: 20 ACKICLEQLRAPKTLPCLHTYCQDCLAQL----------ADGGRVRCPECRETVPVPPEG 69
Query: 65 L-QLRKNHTLSELLQLRQGSGPGSGPGPAPALAPEPSAPSALPSVPEPSAPCAPEPWPAG 123
+ + N ++ LL L + G PA CA P G
Sbjct: 70 VASFKTNFFVNGLLDLVKARACGDLRAGKPA--------------------CALCPLVGG 109
Query: 124 EEPVRCDACPEGAALPAALSCLSCLASFCPAHLGPHERSPALRGHRLV-----------P 172
PA CL C C A H + HR+V
Sbjct: 110 ----------TSTGGPATARCLDCADDLCQACADGHRCTRQTHTHRVVDLVGYRAGWYDE 159
Query: 173 PLRRLEESLCPRHLRPLERY-CRAERVCLCEACAAQEHRGHELVPLEQERALQEAEQSKV 231
R + + CP+H R+ C+ LC C H H +PL + + +
Sbjct: 160 EARERQAAQCPQHPGEALRFLCQPCSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLEGL 219
Query: 232 LSAVEDRMDELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLG---- 287
L+ V++ + EL A + +A ++ A +V AL + +VLG
Sbjct: 220 LAGVDNNLVELEAARRVEKEALARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRA 279
Query: 288 FIEEGEAAMLGRSQGDLRRQEEQRSRLSRARQNLSQVPEADSVSFLQELLALRLALEDGC 347
+E E A R R++ R+ + AR+ LS EA+ +S L+ +A RL GC
Sbjct: 280 HVEAAEEAARERLAELEGREQVARAAAAFARRVLSLGREAEILS-LEGAIAQRLRQLQGC 338
Query: 348 GPGPGP 353
PGP
Sbjct: 339 PWAPGP 344
>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
Length = 511
Score = 94.7 bits (234), Expect = 2e-19
Identities = 139/581 (23%), Positives = 217/581 (37%), Gaps = 145/581 (24%)
Query: 5 GPFSCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAG----GPGGAARCPLCQEP 60
G +C ICLE REPV++ CGH+FC AC+G W GA G P CP C+EP
Sbjct: 25 GEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQCREP 84
Query: 61 FPDGLQLRKNHTLSELLQ-LRQGSGPGSGPGPAPALAPEPSAPSALPSVPEPSAPCAPEP 119
QLR N L+ + LR+ S P + PG + A A +A C
Sbjct: 85 ARPS-QLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARA---------AAARCGQH- 133
Query: 120 WPAGEEPVRCDACPEGAALPAALSCLSCLASFCPAHLGPHERSPALRGHRLVPPLRRLEE 179
EP + +G A+ C+ C +R+ R H ++P ++E
Sbjct: 134 ----GEPFKLYCQDDGRAI-----CVVC------------DRAREHREHAVLPLDEAVQE 172
Query: 180 S--LCPRHLRPLERYCRAERVCLCEACAAQEHRGHELVPLEQERALQEAEQSKVLSAVED 237
+ L LR L++ EL E R+ ++ E ++L +
Sbjct: 173 AKELLESRLRVLKK---------------------ELEDCEVFRSTEKKESKELLKQM-- 209
Query: 238 RMDELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAML 297
AE+E+V F A L + ++LG +EE +
Sbjct: 210 -----------------------AAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVA 246
Query: 298 GRSQGDLRRQEEQRSRLSRARQNLSQVPEADSVSFLQELLALRLALEDGCGPGPGPPREL 357
+ +L + + ++LS+ + + + + FLQE + + PGP P
Sbjct: 247 QKQNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSN--VPGPKPTTVS 304
Query: 358 SFTKSSQAVRAVRDMLAVACVNQW-EQLRGPGGNEDGPQKLDSEADAEPQDLESTNLLES 416
S K+ +++ + + ++ E LRG +L+ E E
Sbjct: 305 SEMKNKVWNVSLKTFVLKGMLKKFKEDLRG---------ELEKEEKVE------------ 343
Query: 417 EAPRDYFLKFAYIVDLDSDTADKFLQL-FGTKGVKRVLCPINYPLSPTRFTHCEQVLGEG 475
+ LD DTA+ L L KGV+ + P P RF +VL
Sbjct: 344 -------------LTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASC 390
Query: 476 ALDRGTYYWEVEI--IEGWVSMGVMAED--------FSPQEPYDRGRLGRNAHSCCLQWN 525
G ++WEVE+ +GW + GV E F+P+E LQ N
Sbjct: 391 GFSSGRHHWEVEVGSKDGW-AFGVARESVRRKGLTPFTPEEGV-----------WALQLN 438
Query: 526 GRSFSVWFHGLEAPLPHPFSPTVGVCLEYADRALAFYAVRD 566
G + +PL V V L+ A++FYAV D
Sbjct: 439 GGQYWAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVED 479
>gi|82617564 tripartite motif-containing 16-like [Homo sapiens]
Length = 348
Score = 93.6 bits (231), Expect = 5e-19
Identities = 81/325 (24%), Positives = 142/325 (43%), Gaps = 29/325 (8%)
Query: 271 FADAAAALQGFQTQVLGFIEEGEAAMLGRSQGDLRRQEEQRSRLSRARQNLSQVPE-ADS 329
F + AA++ Q V+ F+EE E A L ++ G E + + + +++Q L + +++
Sbjct: 3 FGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYRSAEMEKSKQELETMAAISNT 62
Query: 330 VSFLQELLALRLALEDGCGPGPGPPRELSFTKSSQAVRAVRDMLAVACVNQWEQLRGPGG 389
V FL+E + ED P + + +R ++ + V+ + L
Sbjct: 63 VQFLEEYCKFKNT-EDITFPSV-------YIGLKDKLSGIRKVITESTVHLIQLL----- 109
Query: 390 NEDGPQKLDSEADAEPQDLEST----------NLLESEAPRDYFLKFAYIVDLDSDTADK 439
E+ +KL + E D+ + + R+ FL++ + + D DTA K
Sbjct: 110 -ENYKKKLQEFSKEEEYDIRTQVSAIVQRKYWTSKPEPSTREQFLQYVHDITFDPDTAHK 168
Query: 440 FLQLFGTKGVKRVLCPIN--YPLSPTRFTHCEQVLGEGALDRGTYYWEVEIIEGWVSMGV 497
+L+L P YP P+RF H QVL + +L YY+EVEI +G+
Sbjct: 169 YLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYVGL 228
Query: 498 MAEDFSPQEPYDRGRLGRNAHSCCLQWNGRSFSVWFHGLEAPLPHPFSPTVGVCLEYADR 557
+ + + N S LQWNG+ F+ W+ +E PL +GV +++
Sbjct: 229 TCKGIDQKGEERSSCISGNNFSWSLQWNGKEFTAWYSDMETPLKAGPFWRLGVYIDFPGG 288
Query: 558 ALAFYAVRDGKMSLLRRL--KASRP 580
L+FY V M+L+ + K S P
Sbjct: 289 ILSFYGVEYDSMTLVHKFACKFSEP 313
>gi|38679905 tripartite motif-containing 65 [Homo sapiens]
Length = 517
Score = 91.3 bits (225), Expect = 2e-18
Identities = 112/414 (27%), Positives = 163/414 (39%), Gaps = 72/414 (17%)
Query: 182 CPRHLRPLERYCRAERVCLCEACAAQEHRGHELVPLEQERALQEAEQSKVLSAVEDRMDE 241
CPRH RPLE +CR E C+C C +E R HE L+ ER +EA+ L + + +
Sbjct: 95 CPRHGRPLELFCRTEGRCVCSVCTVRECRLHERALLDAERLKREAQLRASLEVTQQQATQ 154
Query: 242 LGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAMLGRSQ 301
+ + R+ + I+++A VS F+ AL+ T L IE + L ++
Sbjct: 155 AEGQLLELRKQSSQIQNSACILASWVSGKFSSLLQALEIQHTTALRSIEVAKTQALAQA- 213
Query: 302 GDLRRQEEQRSRL---------SRARQNLSQVPEADSVSFLQELLALRLALEDGCGPGP- 351
R EEQR R+ R R+ L QV D +FLQE L+ PGP
Sbjct: 214 ----RDEEQRLRVHLEAVARHGCRIRELLEQV---DEQTFLQESQLLQ-------PPGPL 259
Query: 352 GPPRELSFTKSSQAVRAVRDMLAVACVNQWEQLRGPGGNEDGPQKLDSEADAEPQDLEST 411
GP L + + Q + ++ +L+ C E+ PG A A+P DL
Sbjct: 260 GPLTPLQWDEDQQ-LGDLKQLLSRLCGLLLEEGSHPG------------APAKPVDLAPV 306
Query: 412 NLLESEAPRDYFLKFAYIVDLDSDTADKFLQLFGTKGVKRVLCPINYPLS--PTRFTHCE 469
EAP A + K Q + V ++ LS + HC
Sbjct: 307 -----EAPG----PLAPVPSTVCPLRRKLWQNYRNLTFDPVSANRHFYLSRQDQQVKHCR 357
Query: 470 QVLGEG--------------ALDRGTYYWEVEIIEGWVSMGVMAEDFSPQEPYDR----- 510
Q G G + G +YWEV + V++GV PQ P R
Sbjct: 358 QSRGPGGPGSFELWQVQCAQSFQAGHHYWEVRASDHSVTLGVS----YPQLPRCRLGPHT 413
Query: 511 GRLGRNAHSCCLQWNGRSFSVWFHGLEAPLPHPFSPTVGVCLEYADRALAFYAV 564
+GR S L S W +G LP +G+ L+ A L FY++
Sbjct: 414 DNIGRGPCSWGLCVQEDSLQAWHNGEAQRLPGVSGRLLGMDLDLASGCLTFYSL 467
Score = 89.7 bits (221), Expect = 7e-18
Identities = 43/94 (45%), Positives = 58/94 (61%), Gaps = 11/94 (11%)
Query: 8 SCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLCQEPFPDGLQL 67
+C ICL ++PVTLPCGHNFC AC+ W G + CP C+EPFPDG +L
Sbjct: 11 TCAICLGLYQDPVTLPCGHNFCGACIRDWWDRCGKA----------CPECREPFPDGAEL 60
Query: 68 RKNHTLSELLQLRQGSGPGSGPGPAPALAPEPSA 101
R+N LS +L++ + +GP PGP P P+P+A
Sbjct: 61 RRNVALSGVLEVVR-AGPARDPGPDPGPGPDPAA 93
>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
Length = 518
Score = 83.2 bits (204), Expect = 7e-16
Identities = 104/417 (24%), Positives = 164/417 (39%), Gaps = 71/417 (17%)
Query: 178 EESLCPRHLRPLERYCRAERVCLCEACA-AQEHRGHELVPLEQERALQEAEQSKVLSAVE 236
+ESLCP+H L +C ++ +C CA + HR H +VPL+ + + K L +E
Sbjct: 103 DESLCPQHHEALSLFCYEDQEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLE 162
Query: 237 DRMDELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAM 296
++ E+ + + +K + R+++ R F + L Q +L +EE E
Sbjct: 163 QKLQEITRCKSSEEKKPGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEE--- 219
Query: 297 LGRSQGDLRRQEEQRSRLSRARQNLSQVPEADSVSFLQELLALRLALEDGCGPGPGPPRE 356
Q L+R E + L R++L+ + LQ + ++
Sbjct: 220 ----QDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGFEML--------------KD 261
Query: 357 LSFTKSSQAVRAVRDMLAVACVNQWEQLRGPGGNEDGPQKLDS-EADAEPQDLESTNLLE 415
+ T R L+ C + L G + +K+ + E + +LE
Sbjct: 262 VKSTLEKNIPRKFGGSLSTICPRDHKALLGLVKEINRCEKVKTMEVTSVSIELEKNF--- 318
Query: 416 SEAPRDYFLKFAYI------VDLDSDTADKFLQLF-GTKGVKRVLCPI-NYPLSPTRFTH 467
S PR YF + V LD +TA L L K VK V + + P +P RFT
Sbjct: 319 SNFPRQYFALRKILKQLIADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTF 378
Query: 468 CEQVLGEGALDRGTYYWEVEIIE--GWVSMGVMAEDFS--------PQEPYDRGRLGRNA 517
VL G +YWEVE+ + W ++GV + S P+ Y R RL
Sbjct: 379 YPCVLATEGFTSGRHYWEVEVGDKTHW-AVGVCRDSVSRKGELTPLPETGYWRVRL---- 433
Query: 518 HSCCLQWNGRSFSVWFHGLEAPLPHPFSP--------TVGVCLEYADRALAFYAVRD 566
WNG + A PF+P VG+ L+Y L+FY V D
Sbjct: 434 ------WNGDKY--------AATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTD 476
Score = 49.3 bits (116), Expect = 1e-05
Identities = 25/72 (34%), Positives = 36/72 (50%), Gaps = 9/72 (12%)
Query: 8 SCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLCQEPFPDGLQL 67
SC +CLE L+EPV + CGHNFC AC+ W CP+C++ L
Sbjct: 28 SCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERD--------FPCPVCRKT-SRYRSL 78
Query: 68 RKNHTLSELLQL 79
R N L ++++
Sbjct: 79 RPNRQLGSMVEI 90
>gi|239751227 PREDICTED: hypothetical protein XP_002347761 [Homo
sapiens]
Length = 282
Score = 82.8 bits (203), Expect = 9e-16
Identities = 52/166 (31%), Positives = 75/166 (45%), Gaps = 30/166 (18%)
Query: 89 PGPAPALAPEPSAP-------------SALP--------------SVPEPSAPCAPEPWP 121
PGP P +P AP SA P E + A + P
Sbjct: 9 PGPLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGSSEKLGRETEEQDSDSAEQGDP 68
Query: 122 AGE-EPVRCDACPEGAA-LPAALSCLSCLASFCPAHLGPHERSPALRGHRLVPPLRRLEE 179
AGE + V CD C + + A SCL+C+ ++C HL PH+ + L+ H L P++
Sbjct: 69 AGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLTEPVKDHNW 128
Query: 180 SLCPRHLRPLERYCRAERVCLCEACAAQEHRGHELVPLEQERALQE 225
CP H PL +C ++ C+C+ C QEH GH +V L+ R +E
Sbjct: 129 RYCPAHHSPLSAFCCPDQQCICQDC-CQEHSGHTIVSLDAARRDKE 173
>gi|47174859 tripartite motif-containing 46 [Homo sapiens]
Length = 759
Score = 80.9 bits (198), Expect = 3e-15
Identities = 82/335 (24%), Positives = 127/335 (37%), Gaps = 39/335 (11%)
Query: 9 CPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGG-----PGGAARCPLCQEPFPD 63
CP+C E ++P+ LPC HN C AC + +G G GG P A P + P
Sbjct: 33 CPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPASTPSTRSPRLS 92
Query: 64 GLQLRKNHTLSELLQLRQGSGPGSGPG---PAPALAPEPSAPSALPSVPEPSAPC----- 115
L K L LL+ G+ PG G P + P P+ + A
Sbjct: 93 RRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMFPCPACQGDVELGERGLAGLFRNLT 152
Query: 116 ---APEPWPAGEE---PVRCDACPEGAALPAALSCLSCLASFC--------PAHLGPHER 161
E + + C C + L A C C A+FC P +
Sbjct: 153 LERVVERYRQSVSVGGAILCQLC-KPPPLEATKGCTECRATFCNECFKLFHPWGTQKAQH 211
Query: 162 SPALRGHRLVPPLR-RLEESLCPRHLRPLERYCRAERVCLCEACAAQE-HRGHELVPLEQ 219
P L P L R + +CP H + YC+ + +C+ C + H GH++ P+
Sbjct: 212 EPTL------PTLSFRPKGLMCPDHKEEVTHYCKTCQRLVCQLCRVRRTHSGHKITPVLS 265
Query: 220 ERALQEAEQSKVLSAVEDRMDELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQ 279
+ + +K L+ + D + I + V + + +E VS+L A L+
Sbjct: 266 AYQALKDKLTKSLTYILGNQDTVQTQICELEEAVRHTEVSGQQAKEEVSQLVRGLGAVLE 325
Query: 280 GFQTQVLGFIEEGEAAMLGRSQGDLRRQEEQRSRL 314
+ +L IEE + L R + +E RS L
Sbjct: 326 EKRASLLQAIEECQQERLARLSAQI---QEHRSLL 357
>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
Length = 468
Score = 77.8 bits (190), Expect = 3e-14
Identities = 110/448 (24%), Positives = 172/448 (38%), Gaps = 70/448 (15%)
Query: 128 RCDACPEGAALPAALSCLSCLASFCPAHLGPHE--RSPALRGHRLVPPLRRLEESLCPRH 185
RC PEG +C C +L P+ A RL PP + + +CP H
Sbjct: 42 RCWGQPEGP-----YACPECRELSPQRNLRPNRPLAKMAEMARRLHPP-SPVPQGVCPAH 95
Query: 186 LRPLERYCRAERVCLCEACAAQ-EHRGHELVPLEQERALQEAEQSKVLSAVEDRMDELGA 244
PL +C E LC AC EH H + PL+ +A+ K L + +M +
Sbjct: 96 REPLAAFCGDELRLLCAACERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALL 155
Query: 245 GIAQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAMLGRSQGDL 304
AQ+ T L + ++R+ V F L + Q+L +EE E +L R +
Sbjct: 156 FQAQADETCVLWQKMVESQRQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGA 215
Query: 305 RRQEEQRSRLSRARQNLSQVPEADSVSFLQELLALRLALEDGCGPGPGPPRELSFTKSSQ 364
+Q + L+ L + ++ LQ++
Sbjct: 216 AHLGQQSAHLAELIAELEGRCQLPALGLLQDI--------------------------KD 249
Query: 365 AVRAVRDMLAVACVNQWEQLRGPGGNEDGPQKLDSEADAEPQDLESTNLLESEAPRDYFL 424
A+R V+D+ +L+ P E +E + +
Sbjct: 250 ALRRVQDV----------KLQPP----------------EVVPMELRTVCRVPGLVETLR 283
Query: 425 KFAYIVDLDSDTADKFLQLF-GTKGVKRVLCPINYPLSPTRFTHCEQVLGEGALDRGTYY 483
+F V LD DTA+ L L + V+R P SP RF VLG+ G +Y
Sbjct: 284 RFRGDVTLDPDTANPELILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHY 343
Query: 484 WEVEIIE--GWVSMGVMAEDFSPQEPYDRGRLGRNAHSCCLQWNGRSFSVWFHGLEAPLP 541
WEVE+ + W ++GV E+ + +E +G L L + G ++ L APL
Sbjct: 344 WEVEVGDRTSW-ALGVCRENVNRKE---KGELSAGNGFWILVFLGSYYNSSERAL-APLR 398
Query: 542 HPFSPTVGVCLEYADRALAFYAVRDGKM 569
P VG+ L+Y L+FY+ DG +
Sbjct: 399 DP-PRRVGIFLDYEAGHLSFYSATDGSL 425
Score = 58.9 bits (141), Expect = 1e-08
Identities = 65/243 (26%), Positives = 92/243 (37%), Gaps = 68/243 (27%)
Query: 8 SCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLCQEPFPDGLQL 67
+C ICL+ +PV CGHNFC C+ W G P G CP C+E P L
Sbjct: 15 TCAICLDYFTDPVMTDCGHNFCRECIRRCW--------GQPEGPYACPECRELSPQ-RNL 65
Query: 68 RKNHTLSELLQLRQGSGPGSGPGPAPALAPEPSAPSALPSVPEPSAPCAPEPWPAGEEPV 127
R N L+++ ++ + P S P P C PA EP+
Sbjct: 66 RPNRPLAKMAEMARRLHPPS---------------------PVPQGVC-----PAHREPL 99
Query: 128 RCDACPEGAALPAALSCLSCLASFCPAHLGPHERSPALRGHRLVPPLR--------RLEE 179
E L C +C ERS HR V PL+ +LE+
Sbjct: 100 AAFCGDE-----LRLLCAAC------------ERSGEHWAHR-VRPLQDAAEDLKAKLEK 141
Query: 180 SLCPRHLR-----PLERYCRAERVCLCEACAAQEHRGHELVPLEQERALQEAEQSKVLSA 234
SL HLR L +A+ C+ + R + L E+ R L E+ ++L
Sbjct: 142 SL--EHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVLGEFERLRRLLAEEEQQLLQR 199
Query: 235 VED 237
+E+
Sbjct: 200 LEE 202
>gi|148833499 midline 1 [Homo sapiens]
Length = 667
Score = 75.9 bits (185), Expect = 1e-13
Identities = 79/344 (22%), Positives = 133/344 (38%), Gaps = 39/344 (11%)
Query: 8 SCPICLEPLREPVTLPCGHNFCLACL-GALWPHRGASGAGGPGGAARCPLCQEPFP---- 62
+CPICLE +P+ LPC H+ C C L H + + A +CP C+
Sbjct: 9 TCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCRHVITLSQR 68
Query: 63 --DGLQLRKNHTLSELLQLRQGSGPGSGPGPAPALAPEPSAPSALPSVPEPSAPCAPEPW 120
DG L++N TL ++ Q + P+ + + S
Sbjct: 69 GLDG--LKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSA------------ 114
Query: 121 PAGEEPVRCDACPEGAALPAALSCLSCLASFCPAHL-GPHERSPALRGHRLVPPL--RRL 177
E V C C + A A +C++C S+C L H GHRL+ P+ +
Sbjct: 115 ----EKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHI 170
Query: 178 EESLCPRHL-RPLERYCRAERVCLCEAC-AAQEHRGHELVPLEQERALQEAEQSKVLSAV 235
+C H + YC + +C C HR H++ L + + L+ +
Sbjct: 171 RGLMCLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNL 230
Query: 236 EDRMDELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGF-IEEGEA 294
R EL +A+ +T ++ A + +++ D + + Q++G I+EG+
Sbjct: 231 IKRNTELETLLAKLIQTCQHVEVNASRQEAKLTE-ECDLLIEIIQQRRQIIGTKIKEGKV 289
Query: 295 AMLGRSQGDLRR----QEEQRSRLSRARQNLSQVPEADSVSFLQ 334
L + + E S +S+A +L E D FLQ
Sbjct: 290 MRLRKLAQQIANCKQCIERSASLISQAEHSLK---ENDHARFLQ 330
Score = 42.7 bits (99), Expect = 0.001
Identities = 34/107 (31%), Positives = 56/107 (52%), Gaps = 11/107 (10%)
Query: 461 SPTRFTHCEQ--VLGEGALDRGTYYWEVEIIEG--WVSMGVMAEDFSPQEPYDRGRLGRN 516
+P RFT V G +D G +YWEV +I G W ++G +A +P+ + +G+N
Sbjct: 518 TPERFTSQGSYGVAGNVFIDSGRHYWEV-VISGSTWYAIG-LAYKSAPKHEW----IGKN 571
Query: 517 AHSCCLQWNGRSFSVWFHGLEAPL-PHPFSPTVGVCLEYADRALAFY 562
+ S L ++ V + E P+ P P VG+ L+Y + ++AFY
Sbjct: 572 SASWALCRCNNNWVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFY 618
>gi|4557753 midline 1 [Homo sapiens]
Length = 667
Score = 75.9 bits (185), Expect = 1e-13
Identities = 79/344 (22%), Positives = 133/344 (38%), Gaps = 39/344 (11%)
Query: 8 SCPICLEPLREPVTLPCGHNFCLACL-GALWPHRGASGAGGPGGAARCPLCQEPFP---- 62
+CPICLE +P+ LPC H+ C C L H + + A +CP C+
Sbjct: 9 TCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCRHVITLSQR 68
Query: 63 --DGLQLRKNHTLSELLQLRQGSGPGSGPGPAPALAPEPSAPSALPSVPEPSAPCAPEPW 120
DG L++N TL ++ Q + P+ + + S
Sbjct: 69 GLDG--LKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSA------------ 114
Query: 121 PAGEEPVRCDACPEGAALPAALSCLSCLASFCPAHL-GPHERSPALRGHRLVPPL--RRL 177
E V C C + A A +C++C S+C L H GHRL+ P+ +
Sbjct: 115 ----EKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHI 170
Query: 178 EESLCPRHL-RPLERYCRAERVCLCEAC-AAQEHRGHELVPLEQERALQEAEQSKVLSAV 235
+C H + YC + +C C HR H++ L + + L+ +
Sbjct: 171 RGLMCLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNL 230
Query: 236 EDRMDELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGF-IEEGEA 294
R EL +A+ +T ++ A + +++ D + + Q++G I+EG+
Sbjct: 231 IKRNTELETLLAKLIQTCQHVEVNASRQEAKLTE-ECDLLIEIIQQRRQIIGTKIKEGKV 289
Query: 295 AMLGRSQGDLRR----QEEQRSRLSRARQNLSQVPEADSVSFLQ 334
L + + E S +S+A +L E D FLQ
Sbjct: 290 MRLRKLAQQIANCKQCIERSASLISQAEHSLK---ENDHARFLQ 330
Score = 42.7 bits (99), Expect = 0.001
Identities = 34/107 (31%), Positives = 56/107 (52%), Gaps = 11/107 (10%)
Query: 461 SPTRFTHCEQ--VLGEGALDRGTYYWEVEIIEG--WVSMGVMAEDFSPQEPYDRGRLGRN 516
+P RFT V G +D G +YWEV +I G W ++G +A +P+ + +G+N
Sbjct: 518 TPERFTSQGSYGVAGNVFIDSGRHYWEV-VISGSTWYAIG-LAYKSAPKHEW----IGKN 571
Query: 517 AHSCCLQWNGRSFSVWFHGLEAPL-PHPFSPTVGVCLEYADRALAFY 562
+ S L ++ V + E P+ P P VG+ L+Y + ++AFY
Sbjct: 572 SASWALCRCNNNWVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFY 618
>gi|15451852 midline 1 [Homo sapiens]
Length = 667
Score = 75.9 bits (185), Expect = 1e-13
Identities = 79/344 (22%), Positives = 133/344 (38%), Gaps = 39/344 (11%)
Query: 8 SCPICLEPLREPVTLPCGHNFCLACL-GALWPHRGASGAGGPGGAARCPLCQEPFP---- 62
+CPICLE +P+ LPC H+ C C L H + + A +CP C+
Sbjct: 9 TCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCRHVITLSQR 68
Query: 63 --DGLQLRKNHTLSELLQLRQGSGPGSGPGPAPALAPEPSAPSALPSVPEPSAPCAPEPW 120
DG L++N TL ++ Q + P+ + + S
Sbjct: 69 GLDG--LKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSA------------ 114
Query: 121 PAGEEPVRCDACPEGAALPAALSCLSCLASFCPAHL-GPHERSPALRGHRLVPPL--RRL 177
E V C C + A A +C++C S+C L H GHRL+ P+ +
Sbjct: 115 ----EKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHI 170
Query: 178 EESLCPRHL-RPLERYCRAERVCLCEAC-AAQEHRGHELVPLEQERALQEAEQSKVLSAV 235
+C H + YC + +C C HR H++ L + + L+ +
Sbjct: 171 RGLMCLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNL 230
Query: 236 EDRMDELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGF-IEEGEA 294
R EL +A+ +T ++ A + +++ D + + Q++G I+EG+
Sbjct: 231 IKRNTELETLLAKLIQTCQHVEVNASRQEAKLTE-ECDLLIEIIQQRRQIIGTKIKEGKV 289
Query: 295 AMLGRSQGDLRR----QEEQRSRLSRARQNLSQVPEADSVSFLQ 334
L + + E S +S+A +L E D FLQ
Sbjct: 290 MRLRKLAQQIANCKQCIERSASLISQAEHSLK---ENDHARFLQ 330
Score = 42.7 bits (99), Expect = 0.001
Identities = 34/107 (31%), Positives = 56/107 (52%), Gaps = 11/107 (10%)
Query: 461 SPTRFTHCEQ--VLGEGALDRGTYYWEVEIIEG--WVSMGVMAEDFSPQEPYDRGRLGRN 516
+P RFT V G +D G +YWEV +I G W ++G +A +P+ + +G+N
Sbjct: 518 TPERFTSQGSYGVAGNVFIDSGRHYWEV-VISGSTWYAIG-LAYKSAPKHEW----IGKN 571
Query: 517 AHSCCLQWNGRSFSVWFHGLEAPL-PHPFSPTVGVCLEYADRALAFY 562
+ S L ++ V + E P+ P P VG+ L+Y + ++AFY
Sbjct: 572 SASWALCRCNNNWVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFY 618
>gi|223890259 midline 2 isoform 2 [Homo sapiens]
Length = 705
Score = 72.8 bits (177), Expect = 9e-13
Identities = 64/254 (25%), Positives = 100/254 (39%), Gaps = 37/254 (14%)
Query: 8 SCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAG-GPGGAARCPLCQEPFP---- 62
+CPICLE +P+ LPC H+ C +C + +SG P A +CP C+
Sbjct: 29 TCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCRYVISLNHR 88
Query: 63 --DGLQLRKNHTLSELLQLRQGSGPGSGPGPAPALAPEPSAPSALPSVPEPSAPCAPEPW 120
DG L++N TL ++ Q + P+ + P+ S
Sbjct: 89 GLDG--LKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMS------------- 133
Query: 121 PAGEEPVRCDACPEGAALPAALSCLSCLASFCPAHL-GPHERSPALRGHRLVPPL--RRL 177
E + C C + A +C++C S+C L H HRLV P+ L
Sbjct: 134 ---SERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHL 190
Query: 178 EESLCPRH-LRPLERYCRAERVCLCEAC-AAQEHRGHELVPLEQ--ERALQEAEQS---- 229
C H + YC ++ +C C HR H++ L E+ Q E +
Sbjct: 191 RGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNL 250
Query: 230 -KVLSAVEDRMDEL 242
K S +E++M +L
Sbjct: 251 VKRNSELENQMAKL 264
Score = 37.0 bits (84), Expect = 0.056
Identities = 31/106 (29%), Positives = 50/106 (47%), Gaps = 9/106 (8%)
Query: 461 SPTRF--THCEQVLGEGALDRGTYYWEVEI-IEGWVSMGVMAEDFSPQEPYDRGRLGRNA 517
+P RF T C G +D G +YWEV + W ++G+ A +P+ + +G+NA
Sbjct: 538 TPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGI-AYKSAPKNEW----IGKNA 592
Query: 518 HSCCLQWNGRSFSVWFHGLEAPLP-HPFSPTVGVCLEYADRALAFY 562
S +F V + E + P +GV L+Y + L+FY
Sbjct: 593 SSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFY 638
>gi|223890257 midline 2 isoform 1 [Homo sapiens]
Length = 735
Score = 72.8 bits (177), Expect = 9e-13
Identities = 64/254 (25%), Positives = 100/254 (39%), Gaps = 37/254 (14%)
Query: 8 SCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAG-GPGGAARCPLCQEPFP---- 62
+CPICLE +P+ LPC H+ C +C + +SG P A +CP C+
Sbjct: 29 TCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCRYVISLNHR 88
Query: 63 --DGLQLRKNHTLSELLQLRQGSGPGSGPGPAPALAPEPSAPSALPSVPEPSAPCAPEPW 120
DG L++N TL ++ Q + P+ + P+ S
Sbjct: 89 GLDG--LKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMS------------- 133
Query: 121 PAGEEPVRCDACPEGAALPAALSCLSCLASFCPAHL-GPHERSPALRGHRLVPPL--RRL 177
E + C C + A +C++C S+C L H HRLV P+ L
Sbjct: 134 ---SERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHL 190
Query: 178 EESLCPRH-LRPLERYCRAERVCLCEAC-AAQEHRGHELVPLEQ--ERALQEAEQS---- 229
C H + YC ++ +C C HR H++ L E+ Q E +
Sbjct: 191 RGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNL 250
Query: 230 -KVLSAVEDRMDEL 242
K S +E++M +L
Sbjct: 251 VKRNSELENQMAKL 264
Score = 37.0 bits (84), Expect = 0.056
Identities = 31/106 (29%), Positives = 50/106 (47%), Gaps = 9/106 (8%)
Query: 461 SPTRF--THCEQVLGEGALDRGTYYWEVEI-IEGWVSMGVMAEDFSPQEPYDRGRLGRNA 517
+P RF T C G +D G +YWEV + W ++G+ A +P+ + +G+NA
Sbjct: 568 TPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGI-AYKSAPKNEW----IGKNA 622
Query: 518 HSCCLQWNGRSFSVWFHGLEAPLP-HPFSPTVGVCLEYADRALAFY 562
S +F V + E + P +GV L+Y + L+FY
Sbjct: 623 SSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFY 668
>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
Length = 488
Score = 71.6 bits (174), Expect = 2e-12
Identities = 99/417 (23%), Positives = 159/417 (38%), Gaps = 101/417 (24%)
Query: 178 EESLCPRHLRPLERYCRAERVCLCEACA-AQEHRGHELVPLEQERALQEAEQSKVLSAVE 236
+ESLCP+H L +C ++ +C CA + HR H +VPL+ + + K L +E
Sbjct: 103 DESLCPQHHEALSLFCYEDQEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLE 162
Query: 237 DRMDELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAM 296
++ E+ + + +K + R+++ R F + L Q +L
Sbjct: 163 QKLQEITRCKSSEEKKPGELKRLVESRRQQILREFEELHRRLDEEQQVLLS--------- 213
Query: 297 LGRSQGDLRRQEEQRSRLSRARQNLSQVPEADSVSFLQELLALRLALEDGCGPGPGPPRE 356
R +EE++ L R R+N + + + ++L L +E C
Sbjct: 214 --------RLEEEEQDILQRLRENAAHLGDKR-----RDLAHLAAEVEGKC--------- 251
Query: 357 LSFTKSSQAVRAVRDMLAVACVNQWEQLRGPGGNEDGPQKLDS-EADAEPQDLESTNLLE 415
+ +E L+ + +K+ + E + +LE
Sbjct: 252 --------------------LQSGFEMLKDVKSTLEKCEKVKTMEVTSVSIELEKNF--- 288
Query: 416 SEAPRDYFLKFAYI------VDLDSDTADKFLQLF-GTKGVKRVLCPI-NYPLSPTRFTH 467
S PR YF + V LD +TA L L K VK V + + P +P RFT
Sbjct: 289 SNFPRQYFALRKILKQLIADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTF 348
Query: 468 CEQVLGEGALDRGTYYWEVEIIE--GWVSMGVMAEDFS--------PQEPYDRGRLGRNA 517
VL G +YWEVE+ + W ++GV + S P+ Y R RL
Sbjct: 349 YPCVLATEGFTSGRHYWEVEVGDKTHW-AVGVCRDSVSRKGELTPLPETGYWRVRL---- 403
Query: 518 HSCCLQWNGRSFSVWFHGLEAPLPHPFSP--------TVGVCLEYADRALAFYAVRD 566
WNG + A PF+P VG+ L+Y L+FY V D
Sbjct: 404 ------WNGDKY--------AATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTD 446
Score = 49.3 bits (116), Expect = 1e-05
Identities = 25/72 (34%), Positives = 36/72 (50%), Gaps = 9/72 (12%)
Query: 8 SCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLCQEPFPDGLQL 67
SC +CLE L+EPV + CGHNFC AC+ W CP+C++ L
Sbjct: 28 SCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERD--------FPCPVCRKT-SRYRSL 78
Query: 68 RKNHTLSELLQL 79
R N L ++++
Sbjct: 79 RPNRQLGSMVEI 90
>gi|16076875 tripartite motif-containing 7 isoform 4 [Homo sapiens]
Length = 221
Score = 71.6 bits (174), Expect = 2e-12
Identities = 42/105 (40%), Positives = 54/105 (51%), Gaps = 6/105 (5%)
Query: 5 GPFSCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAG----GPGGAARCPLCQEP 60
G +C ICLE REPV++ CGH+FC AC+G W GA G P CP C+EP
Sbjct: 25 GEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQCREP 84
Query: 61 FPDGLQLRKNHTLSELLQ-LRQGSGPGSGPGPAPALAPEPSAPSA 104
QLR N L+ + LR+ S P + PG + A A +A
Sbjct: 85 ARPS-QLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAA 128
Score = 49.7 bits (117), Expect = 8e-06
Identities = 48/180 (26%), Positives = 70/180 (38%), Gaps = 30/180 (16%)
Query: 50 GAARCPLCQEPFPDGLQLRKNHTLSELLQLRQGSGPGSGPGPAPALAPEPSAPSALPSVP 109
G A C +C E F + + + H+ R PG+G A AP
Sbjct: 25 GEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPP----------- 73
Query: 110 EPSAPCAPEPWPAGEEPVRCDACPEGAALPAALSCLSCLASFCPAHLGPHERSPALRGHR 169
P P P EP R L AA++ L S A G H A
Sbjct: 74 ------FPLPCPQCREPARPSQLRPNRQL-AAVATLLRRFSLPAAAPGEHGSQAAAA--- 123
Query: 170 LVPPLRRLEESLCPRHLRPLERYCRAERVCLCEAC-AAQEHRGHELVPLEQERALQEAEQ 228
R + C +H P + YC+ + +C C A+EHR H ++PL++ A+QEA++
Sbjct: 124 ------RAAAARCGQHGEPFKLYCQDDGRAICVVCDRAREHREHAVLPLDE--AVQEAKE 175
>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
Length = 486
Score = 71.6 bits (174), Expect = 2e-12
Identities = 117/487 (24%), Positives = 180/487 (36%), Gaps = 101/487 (20%)
Query: 121 PAGE---EPVRCDACPEGAALPAALSC-----LSCLASFCPAHLG--------PHERSP- 163
P GE E RC C + P ++ C L C++ FC G P R P
Sbjct: 5 PPGERLREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPF 64
Query: 164 ---ALRGHR----LVPPLRRLEESL------CPRHLRPLERYCRAERVCLCEAC-AAQEH 209
R +R LV +RRL C RH L R+C + LC C A EH
Sbjct: 65 RPSGFRPNRQLAGLVESVRRLGLGAGPGARRCARHGEDLSRFCEEDEAALCWVCDAGPEH 124
Query: 210 RGHELVPLEQERALQEAEQSKVLSAVEDRMDELGAGIAQSRRTVALIKSAAVAERERVSR 269
R H PL++ + + L + +++ A + + K +R+R
Sbjct: 125 RTHRTAPLQEAAGSYQVKLQMALELMRKELEDALTQEANVGKKTVIWKEKVEMQRQRFRL 184
Query: 270 LFADAAAALQGFQTQVLGFIEEGEAAMLGRSQGDLRRQE-EQRSRLSRARQNLSQVPEAD 328
F + GF+ + E Q LRR E E+R+ L R R++ S++
Sbjct: 185 EF-----------EKHRGFLAQEE-------QRQLRRLEAEERATLQRLRESKSRL---- 222
Query: 329 SVSFLQELLALRLALEDGCGPGPGPPRELSFTKSSQAVRAVRDMLAVAC----VNQWEQL 384
+ S+A++ + D L C + E +
Sbjct: 223 -------------------------------VQQSKALKELADELQERCQRPALGLLEGV 251
Query: 385 RGPGGNEDGPQKLDSEADAEPQDLESTNLLESEAPRDYFLKFAYIVDLDSDTADKFLQLF 444
RG +L EA+ P +L++ + R+ KF V LD TA L L
Sbjct: 252 RGVLSRSKAVTRL--EAENIPMELKTACCIPGR--RELLRKFQVDVKLDPATAHPSLLLT 307
Query: 445 G-TKGVKRVLCPINYPLSPTRFTHCEQVLGEGALDRGTYYWEVEIIEG--WVSMGVMAED 501
+ V+ + P +P RF +LG + G +YWEV + EG W +GV +D
Sbjct: 308 ADLRSVQDGEPWRDVPNNPERFDTWPCILGLQSFSSGRHYWEVLVGEGAEW-GLGV-CQD 365
Query: 502 FSPQEPYDRGRLGRNAHSCCLQWNGRSFSVWFHGLEAPLPHPFSP-TVGVCLEYADRALA 560
P++ + N G + V PL SP +G+ L+Y ++
Sbjct: 366 TLPRKG-ETTPSPENGVWALWLLKGNEYMV-LASPSVPLLQLESPRCIGIFLDYEAGEIS 423
Query: 561 FYAVRDG 567
FY V DG
Sbjct: 424 FYNVTDG 430
Score = 66.6 bits (161), Expect = 7e-11
Identities = 34/83 (40%), Positives = 47/83 (56%), Gaps = 7/83 (8%)
Query: 9 CPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLCQEPF-PDGLQL 67
CP+CL+ L+EPV++ CGH+FCL C+ G GG CP C+ PF P G
Sbjct: 16 CPVCLDFLQEPVSVDCGHSFCLRCISEFC----EKSDGAQGGVYACPQCRGPFRPSG--F 69
Query: 68 RKNHTLSELLQLRQGSGPGSGPG 90
R N L+ L++ + G G+GPG
Sbjct: 70 RPNRQLAGLVESVRRLGLGAGPG 92
>gi|5730009 ret finger protein [Homo sapiens]
Length = 513
Score = 71.2 bits (173), Expect = 3e-12
Identities = 106/445 (23%), Positives = 184/445 (41%), Gaps = 61/445 (13%)
Query: 142 LSCLSCLASFCPAHLGPHERSPALRGHRLVPPLRRLEES-------LCPRHLRPLERYCR 194
+SC C +F H+ P+ + +LV LR S +C +H PL+ YC
Sbjct: 51 VSCPQCRETFPQRHMRPNRHLANVT--QLVKQLRTERPSGPGGEMGVCEKHREPLKLYCE 108
Query: 195 AERVCLCEAC-AAQEHRGHELVPLEQE-RALQEAEQSKV--LSAVEDRMDELGAGIAQSR 250
+++ +C C ++EHRGH ++PLE+ +E Q+++ L V+D A Q+R
Sbjct: 109 EDQMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQAR 168
Query: 251 RTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAMLGRSQGDLRRQEEQ 310
A + S ERE++ F +L+ + ++L +EE + A+ G + +
Sbjct: 169 ---AELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCN 225
Query: 311 RSRLSRARQNLSQVPEADSVSFLQEL-----LALRLALEDGCGPGPGPPRELSFTKSSQA 365
S LS L + + + LQ++ A R+ + + P PP
Sbjct: 226 ISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPE---PWITPP----------D 272
Query: 366 VRAVRDMLAVACVNQWEQLRGPGGNEDGPQKLDSEADAEPQDLESTNLLESEAPRDYFLK 425
++ + A C+ E L+ +K+ S+ + + Q+L L
Sbjct: 273 LQEKIHIFAQKCLFLTESLK------QFTEKMQSDME-KIQELREAQL------------ 313
Query: 426 FAYIVDLDSDTADKFLQLF-GTKGVKRVLCPINYPLSPTRFTHCEQVLGEGALDRGTYYW 484
++ V LD DTA L L + V+ + P +P RF VLG G +YW
Sbjct: 314 YSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYW 373
Query: 485 EVEIIE--GWVSMGVMAEDFSPQEPYDRGRLGRNAHSCCLQWNGRSFSVWFHGLEA-PLP 541
EVE+ + W ++GV + + +N W G+ + + A PL
Sbjct: 374 EVEVGDKAKW-TIGVCEDSVCRKGGVTSA--PQNGFWAVSLWYGKEYWALTSPMTALPLR 430
Query: 542 HPFSPTVGVCLEYADRALAFYAVRD 566
P VG+ L+Y ++FY V +
Sbjct: 431 TPLQ-RVGIFLDYDAGEVSFYNVTE 454
Score = 60.1 bits (144), Expect = 6e-09
Identities = 33/89 (37%), Positives = 42/89 (47%), Gaps = 15/89 (16%)
Query: 8 SCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLCQEPFPDGLQL 67
+CP+CL+ EP+ L CGHN C ACL W G CP C+E FP +
Sbjct: 15 TCPVCLQYFAEPMMLDCGHNICCACLARCW--------GTAETNVSCPQCRETFPQ-RHM 65
Query: 68 RKNHTLSELLQL------RQGSGPGSGPG 90
R N L+ + QL + SGPG G
Sbjct: 66 RPNRHLANVTQLVKQLRTERPSGPGGEMG 94
>gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo
sapiens]
Length = 442
Score = 70.5 bits (171), Expect = 5e-12
Identities = 110/416 (26%), Positives = 162/416 (38%), Gaps = 38/416 (9%)
Query: 182 CPRHL-RPLERYCRAERVCLCEACAAQ-EHRGHEL-VPLEQERALQEAEQSKVLSAVEDR 238
CP H R E +CR R C+C C HRGH + + LE +Q+ Q + +
Sbjct: 24 CPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKK 83
Query: 239 MDELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAMLG 298
+ I Q +K+ A + + + F + L + FI++ L
Sbjct: 84 QQHID-NITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQLTLQ 142
Query: 299 --RSQGD-LRRQEEQRSRLSRARQNLSQVPEADSVSFLQELLAL------RLALEDGCGP 349
R Q D R Q + + LS ++SQ P D V LQ A +++L + C P
Sbjct: 143 VYREQADSCREQLDIMNDLSNRVWSISQEP--DPVQRLQAYTATEQEMQQQMSLGELCHP 200
Query: 350 GPGPPRELSFTKSSQAVRAVRDMLAVACVNQWEQLRGPGGNEDGPQKLDSEADAEPQDLE 409
P LSF + V++ L A + + E +L + +P L
Sbjct: 201 VP-----LSF----EPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLL 251
Query: 410 STNLLESEAPRDYFLKFAYIVDLDSDTADKFLQLFGTKGVKRVLCPINYPLSPT---RFT 466
T+ R LK+A LD DT L+L + R C + L P RF
Sbjct: 252 KTS---PSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVR--CGLLGSLGPVPVLRFD 306
Query: 467 HCEQVLGEGALDRGTYYWEVEIIE---GWVSMGVMAEDFSPQEPYDRGRLGRNAHSCCLQ 523
QVL G +YWEV++ E GW +G + RLG N S CL+
Sbjct: 307 ALWQVLARDCFATGRHYWEVDVQEAGAGW-WVGAAYASLRRRGASAAARLGCNRQSWCLK 365
Query: 524 WNGRSFSVWFHGLEAPL-PHPFSPTVGVCLEYADRALAFYAVRDGKMSLLRRLKAS 578
+ + G + L P +GV L+Y LAFY V G MS L +A+
Sbjct: 366 RYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGG-MSHLHTFRAT 420
>gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo
sapiens]
Length = 442
Score = 70.5 bits (171), Expect = 5e-12
Identities = 110/416 (26%), Positives = 162/416 (38%), Gaps = 38/416 (9%)
Query: 182 CPRHL-RPLERYCRAERVCLCEACAAQ-EHRGHEL-VPLEQERALQEAEQSKVLSAVEDR 238
CP H R E +CR R C+C C HRGH + + LE +Q+ Q + +
Sbjct: 24 CPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKK 83
Query: 239 MDELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAMLG 298
+ I Q +K+ A + + + F + L + FI++ L
Sbjct: 84 QQHID-NITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQLTLQ 142
Query: 299 --RSQGD-LRRQEEQRSRLSRARQNLSQVPEADSVSFLQELLAL------RLALEDGCGP 349
R Q D R Q + + LS ++SQ P D V LQ A +++L + C P
Sbjct: 143 VYREQADSCREQLDIMNDLSNRVWSISQEP--DPVQRLQAYTATEQEMQQQMSLGELCHP 200
Query: 350 GPGPPRELSFTKSSQAVRAVRDMLAVACVNQWEQLRGPGGNEDGPQKLDSEADAEPQDLE 409
P LSF + V++ L A + + E +L + +P L
Sbjct: 201 VP-----LSF----EPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLL 251
Query: 410 STNLLESEAPRDYFLKFAYIVDLDSDTADKFLQLFGTKGVKRVLCPINYPLSPT---RFT 466
T+ R LK+A LD DT L+L + R C + L P RF
Sbjct: 252 KTS---PSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVR--CGLLGSLGPVPVLRFD 306
Query: 467 HCEQVLGEGALDRGTYYWEVEIIE---GWVSMGVMAEDFSPQEPYDRGRLGRNAHSCCLQ 523
QVL G +YWEV++ E GW +G + RLG N S CL+
Sbjct: 307 ALWQVLARDCFATGRHYWEVDVQEAGAGW-WVGAAYASLRRRGASAAARLGCNRQSWCLK 365
Query: 524 WNGRSFSVWFHGLEAPL-PHPFSPTVGVCLEYADRALAFYAVRDGKMSLLRRLKAS 578
+ + G + L P +GV L+Y LAFY V G MS L +A+
Sbjct: 366 RYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGG-MSHLHTFRAT 420
>gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo
sapiens]
Length = 442
Score = 70.5 bits (171), Expect = 5e-12
Identities = 110/416 (26%), Positives = 162/416 (38%), Gaps = 38/416 (9%)
Query: 182 CPRHL-RPLERYCRAERVCLCEACAAQ-EHRGHEL-VPLEQERALQEAEQSKVLSAVEDR 238
CP H R E +CR R C+C C HRGH + + LE +Q+ Q + +
Sbjct: 24 CPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKK 83
Query: 239 MDELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAMLG 298
+ I Q +K+ A + + + F + L + FI++ L
Sbjct: 84 QQHID-NITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQLTLQ 142
Query: 299 --RSQGD-LRRQEEQRSRLSRARQNLSQVPEADSVSFLQELLAL------RLALEDGCGP 349
R Q D R Q + + LS ++SQ P D V LQ A +++L + C P
Sbjct: 143 VYREQADSCREQLDIMNDLSNRVWSISQEP--DPVQRLQAYTATEQEMQQQMSLGELCHP 200
Query: 350 GPGPPRELSFTKSSQAVRAVRDMLAVACVNQWEQLRGPGGNEDGPQKLDSEADAEPQDLE 409
P LSF + V++ L A + + E +L + +P L
Sbjct: 201 VP-----LSF----EPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLL 251
Query: 410 STNLLESEAPRDYFLKFAYIVDLDSDTADKFLQLFGTKGVKRVLCPINYPLSPT---RFT 466
T+ R LK+A LD DT L+L + R C + L P RF
Sbjct: 252 KTS---PSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVR--CGLLGSLGPVPVLRFD 306
Query: 467 HCEQVLGEGALDRGTYYWEVEIIE---GWVSMGVMAEDFSPQEPYDRGRLGRNAHSCCLQ 523
QVL G +YWEV++ E GW +G + RLG N S CL+
Sbjct: 307 ALWQVLARDCFATGRHYWEVDVQEAGAGW-WVGAAYASLRRRGASAAARLGCNRQSWCLK 365
Query: 524 WNGRSFSVWFHGLEAPL-PHPFSPTVGVCLEYADRALAFYAVRDGKMSLLRRLKAS 578
+ + G + L P +GV L+Y LAFY V G MS L +A+
Sbjct: 366 RYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGG-MSHLHTFRAT 420
>gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens]
Length = 550
Score = 68.9 bits (167), Expect = 1e-11
Identities = 108/424 (25%), Positives = 151/424 (35%), Gaps = 102/424 (24%)
Query: 9 CPICLEPLREPVTLPCGHNFCLACLGALW----------PHRGA---------------- 42
CP+C REP+ LPC HN C AC + HR A
Sbjct: 10 CPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDYDYLDLDKMS 69
Query: 43 ------SGAGGPGGAARCPL--CQEPFPDGLQLRKNHTLSELLQLRQGSGPGSGPGPAPA 94
SG G GG A P CQ+ P+G+++ P + P PA
Sbjct: 70 LYSEADSGYGSYGGFASAPTTPCQKS-PNGVRVF----------------PPAMPPPATH 112
Query: 95 LAPEPSAPSALPSVPEPSAPCAPE-------------PWPAGE--------------EPV 127
L+P AL VP S P+ +P +
Sbjct: 113 LSP------ALAPVPRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAAL 166
Query: 128 RCDACPEGAALPAALSCLSCLASFC-PAHLGPHERSPALRGHRLVPPLR-RLEESLCPR- 184
+C C E A A + C C +C P L H L HRLVPP + R+ L PR
Sbjct: 167 KCQLC-EKAPKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRK 225
Query: 185 -------HLRPLERYCRAERVCLCEACAAQ-EHRGHELVPLEQERALQEAEQSKVLSAVE 236
L YC ++ +C C + +H HE+ L L +++ S+ L+ +
Sbjct: 226 VSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLS 285
Query: 237 DRMDELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAA-ALQGFQTQVLGFIEEGEAA 295
DR E + Q R V I+ +V E E DA AL + Q+L + +
Sbjct: 286 DRAKEAKEFLVQLRNMVQQIQENSV-EFEACLVAQCDALIDALNRRKAQLLARVNKEHEH 344
Query: 296 MLGRSQGDLRR-QEEQRSRLSRARQNLSQVPEADSVSFLQ--ELLALRLAL-EDGCGPGP 351
L + + + R L + E D FLQ + L R+ L ED G G
Sbjct: 345 KLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGT 404
Query: 352 GPPR 355
PR
Sbjct: 405 LTPR 408
>gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]
Length = 710
Score = 68.9 bits (167), Expect = 1e-11
Identities = 108/424 (25%), Positives = 151/424 (35%), Gaps = 102/424 (24%)
Query: 9 CPICLEPLREPVTLPCGHNFCLACLGALW----------PHRGA---------------- 42
CP+C REP+ LPC HN C AC + HR A
Sbjct: 10 CPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDYDYLDLDKMS 69
Query: 43 ------SGAGGPGGAARCPL--CQEPFPDGLQLRKNHTLSELLQLRQGSGPGSGPGPAPA 94
SG G GG A P CQ+ P+G+++ P + P PA
Sbjct: 70 LYSEADSGYGSYGGFASAPTTPCQKS-PNGVRVF----------------PPAMPPPATH 112
Query: 95 LAPEPSAPSALPSVPEPSAPCAPE-------------PWPAGE--------------EPV 127
L+P AL VP S P+ +P +
Sbjct: 113 LSP------ALAPVPRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAAL 166
Query: 128 RCDACPEGAALPAALSCLSCLASFC-PAHLGPHERSPALRGHRLVPPLR-RLEESLCPR- 184
+C C E A A + C C +C P L H L HRLVPP + R+ L PR
Sbjct: 167 KCQLC-EKAPKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRK 225
Query: 185 -------HLRPLERYCRAERVCLCEACAAQ-EHRGHELVPLEQERALQEAEQSKVLSAVE 236
L YC ++ +C C + +H HE+ L L +++ S+ L+ +
Sbjct: 226 VSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLS 285
Query: 237 DRMDELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAA-ALQGFQTQVLGFIEEGEAA 295
DR E + Q R V I+ +V E E DA AL + Q+L + +
Sbjct: 286 DRAKEAKEFLVQLRNMVQQIQENSV-EFEACLVAQCDALIDALNRRKAQLLARVNKEHEH 344
Query: 296 MLGRSQGDLRR-QEEQRSRLSRARQNLSQVPEADSVSFLQ--ELLALRLAL-EDGCGPGP 351
L + + + R L + E D FLQ + L R+ L ED G G
Sbjct: 345 KLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGT 404
Query: 352 GPPR 355
PR
Sbjct: 405 LTPR 408
>gi|84993742 tripartite motif-containing 71 [Homo sapiens]
Length = 868
Score = 68.2 bits (165), Expect = 2e-11
Identities = 92/392 (23%), Positives = 141/392 (35%), Gaps = 90/392 (22%)
Query: 22 LPCGHNFCLACLGALWPHRGASGAGGPGG---AARCPLC-----------QEPFPDGLQL 67
LPC H FC CL A HR + GG G RCP+C + P L
Sbjct: 59 LPCLHAFCRPCLEA---HRLPAAGGGAAGEPLKLRCPVCDQKVVLAEAAGMDALPSSAFL 115
Query: 68 RKNHTLSELLQLRQGSGPGSGPGPAPALA--------------PEPSAPS-ALPSVPEPS 112
N L ++ P +G APA A P SA + LP P+P
Sbjct: 116 LSN-LLDAVVATADEPPPKNGRAGAPAGAGGHSNHRHHAHHAHPRASASAPPLPQAPQPP 174
Query: 113 APCAPEP-WPAG-------EEPVRCDACPEGAALPAALSCLSCLASFCPAHLGPHERSPA 164
AP P PA P C +C EG A A+ CL C C + H+R
Sbjct: 175 APSRSAPGGPAASPSALLLRRPHGCSSCDEGNA--ASSRCLDCQEHLCDNCVRAHQRVRL 232
Query: 165 LRGHRLV-----------------------PPLRRLEE-----SLCPRH-LRPLERYCRA 195
+ H + PP L C H L YC
Sbjct: 233 TKDHYIERGPPGPGAAAAAQQLGLGPPFPGPPFSILSVFPERLGFCQHHDDEVLHLYCDT 292
Query: 196 ERVCLCEACAAQEHRGHELVPLEQERALQEAEQSKVLSAVEDRMDELGAGIAQSRRTVAL 255
V +C C H GH + L++ A ++L+ + + I Q++
Sbjct: 293 CSVPICRECTMGRHGGHSFIYLQEALQDSRALTIQLLADAQQGRQAIQLSIEQAQTVAEQ 352
Query: 256 IKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAMLGRSQGDLRRQEEQRS--- 312
++ A + V + A AL+ + ++L +E+ RQ + +S
Sbjct: 353 VEMKAKVVQSEVKAVTARHKKALEERECELLWKVEK-------------IRQVKAKSLYL 399
Query: 313 RLSRARQNLSQVPEADSVSFLQELLALRLALE 344
++ + RQNL+++ ++S +Q++L AL+
Sbjct: 400 QVEKLRQNLNKL--ESTISAVQQVLEEGRALD 429
>gi|56605981 tripartite motif-containing 72 [Homo sapiens]
Length = 477
Score = 64.7 bits (156), Expect = 2e-10
Identities = 66/243 (27%), Positives = 100/243 (41%), Gaps = 32/243 (13%)
Query: 129 CDAC-PEGAALPAALSCLSCLASFCPAHLGPHERSPALRGHRLVPPLRRLEESLCPRHLR 187
C AC A PAA + C C A P S L+ RLV L ++ + C HL
Sbjct: 34 CRACLGRVAGEPAADGTVLCPC--CQAPTRPQALSTNLQLARLVEGLAQVPQGHCEEHLD 91
Query: 188 PLERYCRAERVCLCEACAA-QEHRGHELVPL------------EQERALQEA--EQSKVL 232
PL YC +R +C CA+ HRGH L+P +Q+ LQEA + K +
Sbjct: 92 PLSIYCEQDRALVCGVCASLGSHRGHRLLPAAEAHARLKTQLPQQKLQLQEACMRKEKSV 151
Query: 233 SAVEDRMDELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEG 292
+ +E ++ E+ + Q R AV E+ R+F AAL+G +
Sbjct: 152 AVLEHQLVEVEETVRQFR--------GAVGEQLGKMRVF---LAALEGSLDCEAERVRGE 200
Query: 293 EAAMLGRSQGDLRRQEEQRSRLSRARQNLSQVPEADSVSFLQELLALRLALEDGCGPGPG 352
L R G L EQ ++ + + ++ P+ + FL + + L+ P
Sbjct: 201 AGVALRRELGSLNSYLEQLRQMEKVLEEVADKPQTE---FLMKYCLVTSRLQKILAESPP 257
Query: 353 PPR 355
P R
Sbjct: 258 PAR 260
>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
sapiens]
Length = 481
Score = 61.2 bits (147), Expect = 3e-09
Identities = 32/71 (45%), Positives = 39/71 (54%), Gaps = 5/71 (7%)
Query: 8 SCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLCQEPFPDGLQL 67
+CPIC LREPVT+ CGHNFC ACL G P CPLC+EPF G
Sbjct: 15 NCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESP----TCPLCKEPFRPG-SF 69
Query: 68 RKNHTLSELLQ 78
R N L+ +++
Sbjct: 70 RPNWQLANVVE 80
Score = 43.1 bits (100), Expect = 8e-04
Identities = 41/181 (22%), Positives = 74/181 (40%), Gaps = 13/181 (7%)
Query: 135 GAALPAALSCLSCLASFCPAHLGPHERSPALRGH----RLVPPLRRLEESLCPRHLRPLE 190
G L + +C C F P P+ + + + +LV L EE +C H +
Sbjct: 48 GPDLEESPTCPLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIY 107
Query: 191 RYCRAERVCLCEAC-AAQEHRGHELVPLEQERALQEAEQSKVLSAVEDRMDELGAGIAQS 249
+C + + LC C A EH H + LE A + K L + +E+ ++
Sbjct: 108 FFCEDDEMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRE 167
Query: 250 RRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAMLGRSQGDLRRQEE 309
+ + ++ + +R++V FA L+ Q+ +L A L GD+ RQ +
Sbjct: 168 NKRMQVLLTQVSTKRQQVISEFAHLRKFLEEQQSILL--------AQLESQDGDILRQRD 219
Query: 310 Q 310
+
Sbjct: 220 E 220
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,701,029
Number of Sequences: 37866
Number of extensions: 1865458
Number of successful extensions: 19725
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 353
Number of HSP's successfully gapped in prelim test: 808
Number of HSP's that attempted gapping in prelim test: 14117
Number of HSP's gapped (non-prelim): 4849
length of query: 638
length of database: 18,247,518
effective HSP length: 109
effective length of query: 529
effective length of database: 14,120,124
effective search space: 7469545596
effective search space used: 7469545596
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.