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Search of human proteins with 51988900
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51988900 XPG-complementing protein [Homo sapiens]
(1186 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|51988900 XPG-complementing protein [Homo sapiens] 2336 0.0
gi|194018535 Gen homolog 1, endonuclease [Homo sapiens] 93 1e-18
gi|194018531 Gen homolog 1, endonuclease [Homo sapiens] 93 1e-18
gi|4758356 flap structure-specific endonuclease 1 [Homo sapiens] 74 6e-13
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 52 3e-06
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 50 2e-05
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 50 2e-05
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 50 2e-05
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 49 2e-05
gi|150170670 piccolo isoform 2 [Homo sapiens] 47 8e-05
gi|150378539 piccolo isoform 1 [Homo sapiens] 47 8e-05
gi|19923599 calmin [Homo sapiens] 47 1e-04
gi|39995071 exonuclease 1 isoform b [Homo sapiens] 46 2e-04
gi|39995069 exonuclease 1 isoform a [Homo sapiens] 46 2e-04
gi|18491016 exonuclease 1 isoform b [Homo sapiens] 46 2e-04
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 46 2e-04
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 45 4e-04
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 45 4e-04
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 45 5e-04
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 45 5e-04
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 45 5e-04
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 45 5e-04
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 45 5e-04
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 45 5e-04
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 45 5e-04
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 45 5e-04
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 44 0.001
gi|38261962 activating transcription factor 7 interacting protei... 44 0.001
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 44 0.001
gi|38176300 nestin [Homo sapiens] 43 0.002
>gi|51988900 XPG-complementing protein [Homo sapiens]
Length = 1186
Score = 2336 bits (6054), Expect = 0.0
Identities = 1186/1186 (100%), Positives = 1186/1186 (100%)
Query: 1 MGVQGLWKLLECSGRQVSPEALEGKILAVDISIWLNQALKGVRDRHGNSIENPHLLTLFH 60
MGVQGLWKLLECSGRQVSPEALEGKILAVDISIWLNQALKGVRDRHGNSIENPHLLTLFH
Sbjct: 1 MGVQGLWKLLECSGRQVSPEALEGKILAVDISIWLNQALKGVRDRHGNSIENPHLLTLFH 60
Query: 61 RLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIK 120
RLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIK
Sbjct: 61 RLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIK 120
Query: 121 TAFRSKRDEALPSLTQVRRENDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFF 180
TAFRSKRDEALPSLTQVRRENDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFF
Sbjct: 121 TAFRSKRDEALPSLTQVRRENDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFF 180
Query: 181 HNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRRTLFEAMPEESDDFSQYQLKGLLKK 240
HNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRRTLFEAMPEESDDFSQYQLKGLLKK
Sbjct: 181 HNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRRTLFEAMPEESDDFSQYQLKGLLKK 240
Query: 241 NYLNQHIEHVQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTV 300
NYLNQHIEHVQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTV
Sbjct: 241 NYLNQHIEHVQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTV 300
Query: 301 AEVDSESLPSSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEE 360
AEVDSESLPSSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEE
Sbjct: 301 AEVDSESLPSSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEE 360
Query: 361 LESENRRQARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMR 420
LESENRRQARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMR
Sbjct: 361 LESENRRQARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMR 420
Query: 421 INSSTENSDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVH 480
INSSTENSDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVH
Sbjct: 421 INSSTENSDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVH 480
Query: 481 VGTEAFPISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHA 540
VGTEAFPISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHA
Sbjct: 481 VGTEAFPISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHA 540
Query: 541 EVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNV 600
EVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNV
Sbjct: 541 EVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNV 600
Query: 601 ENVVSFNAKEHENFLETIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSV 660
ENVVSFNAKEHENFLETIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSV
Sbjct: 601 ENVVSFNAKEHENFLETIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSV 660
Query: 661 ISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKD 720
ISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKD
Sbjct: 661 ISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKD 720
Query: 721 AEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATVTGQMFLESQELLRLFG 780
AEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATVTGQMFLESQELLRLFG
Sbjct: 721 AEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATVTGQMFLESQELLRLFG 780
Query: 781 IPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFNKNKFVEYYQYVDF 840
IPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFNKNKFVEYYQYVDF
Sbjct: 781 IPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFNKNKFVEYYQYVDF 840
Query: 841 HNQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGHGLEPLLKFSEWWHEAQ 900
HNQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGHGLEPLLKFSEWWHEAQ
Sbjct: 841 HNQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGHGLEPLLKFSEWWHEAQ 900
Query: 901 KNPKIRPNPHDTKVKKKLRTLQLTPGFPNPAVAEAYLKPVVDDSKGSFLWGKPDLDKIRE 960
KNPKIRPNPHDTKVKKKLRTLQLTPGFPNPAVAEAYLKPVVDDSKGSFLWGKPDLDKIRE
Sbjct: 901 KNPKIRPNPHDTKVKKKLRTLQLTPGFPNPAVAEAYLKPVVDDSKGSFLWGKPDLDKIRE 960
Query: 961 FCQRYFGWNRTKTDESLFPVLKQLDAQQTQLRIDSFFRLAQQEKEDAKRIKSQRLNRAVT 1020
FCQRYFGWNRTKTDESLFPVLKQLDAQQTQLRIDSFFRLAQQEKEDAKRIKSQRLNRAVT
Sbjct: 961 FCQRYFGWNRTKTDESLFPVLKQLDAQQTQLRIDSFFRLAQQEKEDAKRIKSQRLNRAVT 1020
Query: 1021 CMLRKEKEAAASEIEAVSVAMEKEFELLDKAKRKTQKRGITNTLEESSSLKRKRLSDSKR 1080
CMLRKEKEAAASEIEAVSVAMEKEFELLDKAKRKTQKRGITNTLEESSSLKRKRLSDSKR
Sbjct: 1021 CMLRKEKEAAASEIEAVSVAMEKEFELLDKAKRKTQKRGITNTLEESSSLKRKRLSDSKR 1080
Query: 1081 KNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTSASDSQNSVKEAPVKN 1140
KNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTSASDSQNSVKEAPVKN
Sbjct: 1081 KNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTSASDSQNSVKEAPVKN 1140
Query: 1141 GGATTSSSSDSDDDGGKEKMVLVTARSVFGKKRRKLRRARGRKRKT 1186
GGATTSSSSDSDDDGGKEKMVLVTARSVFGKKRRKLRRARGRKRKT
Sbjct: 1141 GGATTSSSSDSDDDGGKEKMVLVTARSVFGKKRRKLRRARGRKRKT 1186
>gi|194018535 Gen homolog 1, endonuclease [Homo sapiens]
Length = 908
Score = 93.2 bits (230), Expect = 1e-18
Identities = 55/163 (33%), Positives = 92/163 (56%), Gaps = 8/163 (4%)
Query: 739 LESNLLAQQNSLK---AQKQQQERIAATVTGQMFLESQELLRLFGIPYIQAPMEAEAQCA 795
L++++++++N + + K ++ + + E +L GIP++QA EAEA CA
Sbjct: 81 LKADVISKRNQSRYGSSGKSWSQKTGRSHFKSVLRECLHMLECLGIPWVQAAGEAEAMCA 140
Query: 796 ILDLTDQTSGTITDDSDIWLFGARHVYRNFF--NKNKFVEYYQYVDFHNQLGLDRNKLIN 853
L+ G +T+D D +L+GA+ VYRNF K+ V+ Y ++LGLDR+ L+
Sbjct: 141 YLNAGGHVDGCLTNDGDTFLYGAQTVYRNFTMNTKDPHVDCYTMSSIKSKLGLDRDALVG 200
Query: 854 LAYLLGSDY-TEGIPTVGCVTAMEILNEFPGHGLEPLLKFSEW 895
LA LLG DY +G+P VG A++++ G L L +F+ W
Sbjct: 201 LAILLGCDYLPKGVPGVGKEQALKLIQILKGQSL--LQRFNRW 241
Score = 65.5 bits (158), Expect = 3e-10
Identities = 41/117 (35%), Positives = 64/117 (54%), Gaps = 4/117 (3%)
Query: 1 MGVQGLWKLLECSGRQVSPEALEGKILAVDISIWLNQALKGVRDRHGNSIENPHLLTLFH 60
MGV LW++LE + + L GK +AVD+S+W+ +A + V+ G S+ PHL LF
Sbjct: 1 MGVNDLWQILEPVKQHIPLRNLGGKTIAVDLSLWVCEA-QTVKKMMG-SVMKPHLRNLFF 58
Query: 61 RLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRK--DLASSDSRKTTEKLLKTFLK 115
R+ L ++ +FV +G+ P LK + KR Q + S S+KT K+ L+
Sbjct: 59 RISYLTQMDVKLVFVMEGEPPKLKADVISKRNQSRYGSSGKSWSQKTGRSHFKSVLR 115
>gi|194018531 Gen homolog 1, endonuclease [Homo sapiens]
Length = 908
Score = 93.2 bits (230), Expect = 1e-18
Identities = 55/163 (33%), Positives = 92/163 (56%), Gaps = 8/163 (4%)
Query: 739 LESNLLAQQNSLK---AQKQQQERIAATVTGQMFLESQELLRLFGIPYIQAPMEAEAQCA 795
L++++++++N + + K ++ + + E +L GIP++QA EAEA CA
Sbjct: 81 LKADVISKRNQSRYGSSGKSWSQKTGRSHFKSVLRECLHMLECLGIPWVQAAGEAEAMCA 140
Query: 796 ILDLTDQTSGTITDDSDIWLFGARHVYRNFF--NKNKFVEYYQYVDFHNQLGLDRNKLIN 853
L+ G +T+D D +L+GA+ VYRNF K+ V+ Y ++LGLDR+ L+
Sbjct: 141 YLNAGGHVDGCLTNDGDTFLYGAQTVYRNFTMNTKDPHVDCYTMSSIKSKLGLDRDALVG 200
Query: 854 LAYLLGSDY-TEGIPTVGCVTAMEILNEFPGHGLEPLLKFSEW 895
LA LLG DY +G+P VG A++++ G L L +F+ W
Sbjct: 201 LAILLGCDYLPKGVPGVGKEQALKLIQILKGQSL--LQRFNRW 241
Score = 65.5 bits (158), Expect = 3e-10
Identities = 41/117 (35%), Positives = 64/117 (54%), Gaps = 4/117 (3%)
Query: 1 MGVQGLWKLLECSGRQVSPEALEGKILAVDISIWLNQALKGVRDRHGNSIENPHLLTLFH 60
MGV LW++LE + + L GK +AVD+S+W+ +A + V+ G S+ PHL LF
Sbjct: 1 MGVNDLWQILEPVKQHIPLRNLGGKTIAVDLSLWVCEA-QTVKKMMG-SVMKPHLRNLFF 58
Query: 61 RLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRK--DLASSDSRKTTEKLLKTFLK 115
R+ L ++ +FV +G+ P LK + KR Q + S S+KT K+ L+
Sbjct: 59 RISYLTQMDVKLVFVMEGEPPKLKADVISKRNQSRYGSSGKSWSQKTGRSHFKSVLR 115
>gi|4758356 flap structure-specific endonuclease 1 [Homo sapiens]
Length = 380
Score = 74.3 bits (181), Expect = 6e-13
Identities = 70/269 (26%), Positives = 119/269 (44%), Gaps = 37/269 (13%)
Query: 740 ESNLLAQQNSLKAQKQQQERIA---ATVTGQMFLESQELLRLFGIPYIQAPMEAEAQCAI 796
E+ QQ +Q+ E+ VT Q E + LL L GIPY+ AP EAEA CA
Sbjct: 106 EAEKQLQQAQAAGAEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAA 165
Query: 797 LDLTDQTSGTITDDSDIWLFGA----RHVYRNFFNKNKFVEYYQYVDFHNQLGLDRNKLI 852
L + T+D D FG+ RH+ + K E++ +LGL++ + +
Sbjct: 166 LVKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFH-LSRILQELGLNQEQFV 224
Query: 853 NLAYLLGSDYTEGIPTVGCVTAMEILNEFPGHGLEPLLKFSEWWHEAQKNPKIRPNPHDT 912
+L LLGSDY E I +G A++++ + +E +++ + +P P P +
Sbjct: 225 DLCILLGSDYCESIRGIGPKRAVDLIQKH--KSIEEIVR--------RLDPNKYPVP-EN 273
Query: 913 KVKKKLRTLQLTPGFPNPAVAEAYLKPVVDDSKGSFLWGKPDLDKIREFC--QRYFGWNR 970
+ K+ L L P V+D W +P+ +++ +F ++ F R
Sbjct: 274 WLHKEAHQLFLEP-------------EVLDPESVELKWSEPNEEELIKFMCGEKQFSEER 320
Query: 971 TKTDESLFPVLKQLDAQQTQLRIDSFFRL 999
++ +Q TQ R+D FF++
Sbjct: 321 IRSGVKRLSKSRQ---GSTQGRLDDFFKV 346
Score = 56.6 bits (135), Expect = 1e-07
Identities = 42/134 (31%), Positives = 71/134 (52%), Gaps = 23/134 (17%)
Query: 1 MGVQGLWKLLECSGRQVSPEALE--------GKILAVDISIWLNQALKGVRDRHGNSIEN 52
MG+QGL KL+ V+P A+ G+ +A+D S+ + Q L VR + G+ ++N
Sbjct: 1 MGIQGLAKLIA----DVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVR-QGGDVLQN 55
Query: 53 P------HLLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASSDSRKT- 105
HL+ +F+R +++ I+P++VFDG P LK L KR +R+ A ++
Sbjct: 56 EEGETTSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQ 115
Query: 106 ---TEKLLKTFLKR 116
E+ ++ F KR
Sbjct: 116 AAGAEQEVEKFTKR 129
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 52.0 bits (123), Expect = 3e-06
Identities = 125/644 (19%), Positives = 236/644 (36%), Gaps = 89/644 (13%)
Query: 150 QEEEKHSSEEEDEKEWQERMNQKQALQE--EFFHNPQAIDIESEDFSSLPPEVKHEILTD 207
QE +K +++ EK+ Q+ ++ L+E E Q I + E + P E E T
Sbjct: 35 QEPQKSKGKKKKEKKKQD-FDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTS 93
Query: 208 MKEFTK----RRRTLFEAMPEESDDFSQYQLKGLLKK-------------NYLNQHIEHV 250
+ K ++++ + EE +D K K N L + +
Sbjct: 94 KDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGK 153
Query: 251 QKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVS-----EDTSHYILIKGIQAKTVAEVDS 305
++ N++ G EDE K E R+ S +++ ++ + Q K
Sbjct: 154 AQKSNKKWDG----SEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPG 209
Query: 306 ESLPSSSKMHGMSFDVKSSPCEKL-KTEKEPDATPPSPRTLLAMQAALLGSSSEEELESE 364
++ S ++ SF +K+ +K K E+E +A L +EELE+
Sbjct: 210 PNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEE-------KAKLRKLKEKEELETG 262
Query: 365 NRRQARGRNAPAAVDEGSISPRTL--SAIKRALDDDEDVKVCAGDDVQTGGPGAEEMRIN 422
+ Q++ + + +E ++ + + + A ++ + A DD + ++ +
Sbjct: 263 KKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKK 322
Query: 423 SSTENSDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGR----EPTDSVPKEQMSL 478
E ++ K K A + + EE E R E ++ KE+ L
Sbjct: 323 GEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERL 382
Query: 479 VHVGTEAFPISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNET 538
E + K+RK+RL E ++ S + ++ E
Sbjct: 383 EQEKRER----KKQKEKERKERLKKEGKLLTKSQR-----------------EARARAEA 421
Query: 539 HAEVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVD 598
++L+ Q P S D K +P + + Q S VS E
Sbjct: 422 TLKLLQAQGVEVP----------SKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCA 471
Query: 599 NVENVVSFNAKEHENFLETIQ--EQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIE 656
VE V+ E E ++ E++ TE AG D E M D E + +G+ +
Sbjct: 472 AVE-VMEQGVPEKEETPPPVEPEEEEDTEDAGLD------DWEAMASDEETEKVEGNKVH 524
Query: 657 VQSVISDEELQAEFPETSKPPSEQGEEELVGTREG-EAPAESESLLRDNSERDDVDGEP- 714
++ + EE + E E + + EEE G EG E E E + + +D +P
Sbjct: 525 IEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPS 584
Query: 715 ----QEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQK 754
++E D++D + + + +E L ++ +K
Sbjct: 585 KEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEK 628
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 49.7 bits (117), Expect = 2e-05
Identities = 91/405 (22%), Positives = 156/405 (38%), Gaps = 71/405 (17%)
Query: 336 DATPPSPRTLLAMQAALLGSSSEEELESENRRQARGRNAPAAVDEGSISPRTLSAIKRAL 395
D + P P+ + LGS + S++ QA +AP +G S + ++ R L
Sbjct: 117 DDSGPGPKDRQEGGNSRLGSDED----SDDTIQASEESAP----QGQDSAQDTTSESREL 168
Query: 396 DDDE--DVKVCAGDDVQ--------TGGPGAEEMRINSSTENSDEGLKVRDGKGIPFTAT 445
D+++ D K GD Q GG E +E DEG++ D + I +
Sbjct: 169 DNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESI--RSE 226
Query: 446 LASSSVNSAEEHVASTNEGREPTDSVPKEQMSLV-HVGTEAFPISDESMIKDRKDRLPLE 504
+S +NSA + E E ++ L+ H + F S S DR +
Sbjct: 227 RGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNN 286
Query: 505 SAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQNELCPYESKFDSSLLSSD 564
+ SD+ N R+ + P + E E L Q+ +
Sbjct: 287 TMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQE-----------------E 329
Query: 565 DETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHEN----FLETIQE 620
+ P+S S +S QE SS ++ E VVS + ++ + ++E ++
Sbjct: 330 SQNVDGPSSESSQEANLSSQENSS---------ESQEEVVSESRGDNPDPTTSYVEDQED 380
Query: 621 QQTTESAGQDLISIPKAVEPME-IDSEESESDGSFIEVQSVISDEELQAEFPETSKPPSE 679
++E +S K+ E DSE SES ++ E E PE S+
Sbjct: 381 SDSSEEDSSHTLSHSKSESREEQADSESSES----------LNFSEESPESPEDENSSSQ 430
Query: 680 QGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKDAEDS 724
+ G + + AES+S + S ++ D + Q++ + EDS
Sbjct: 431 E------GLQSHSSSAESQS---EESHSEEDDSDSQDSSRSKEDS 466
Score = 40.4 bits (93), Expect = 0.010
Identities = 39/167 (23%), Positives = 75/167 (44%), Gaps = 12/167 (7%)
Query: 994 DSFFRLAQQEKEDAKRIKSQRLNRAVTCMLRKEKEAAASEIEAVSVAMEKEFE-----LL 1048
DS L+Q+E ++ S+ A L ++ ++ S+ E VS + + +
Sbjct: 320 DSKENLSQEESQNVDGPSSESSQEA---NLSSQENSSESQEEVVSESRGDNPDPTTSYVE 376
Query: 1049 DKAKRKTQKRGITNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESS 1108
D+ + + ++TL S S R+ +DS+ + F E+ S + SSS++ S
Sbjct: 377 DQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLN-FSEESPESPEDENSSSQEGLQS 435
Query: 1109 SLMNVQRRTAAKEPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDG 1155
+ + ++ + SDSQ+S + K +T S S S++DG
Sbjct: 436 HSSSAESQSEESHSEEDDSDSQDSSRS---KEDSNSTESKSSSEEDG 479
Score = 37.4 bits (85), Expect = 0.086
Identities = 94/481 (19%), Positives = 172/481 (35%), Gaps = 104/481 (21%)
Query: 322 KSSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEELESENRRQARGRNAPAAVDEG 381
+S E+ K TPP L + +++ S EE +E+ + D+
Sbjct: 26 ESEDSEEWKGHLAQAPTPP----LESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSDDH 81
Query: 382 SISPRTLSAIKRAL----DDDEDVKVCAGDDV---QTGGPGAEEMRINS-----STENSD 429
R R+ DD +D + +GDD GPG ++ + S E+SD
Sbjct: 82 QYIYRLAGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSD 141
Query: 430 EGLKVRD-----GKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTE 484
+ ++ + G+ T S +++ E+ V S EG + T E+ V G++
Sbjct: 142 DTIQASEESAPQGQDSAQDTTSESRELDN-EDRVDSKPEGGDSTQESESEE-HWVGGGSD 199
Query: 485 A-------FPISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNE 537
+ DE M D + + E R + A G + + + +++
Sbjct: 200 GESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSA-----GMKSKESGENSEQANTQDS 254
Query: 538 THAEVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAV 597
+++LE P F S +S +D+ L + +++ V S++
Sbjct: 255 GGSQLLEH-----PSRKIFRKSRISEEDDRS-------------ELDDNNTMEEVKSDST 296
Query: 598 DNVENVVSFNAKEHENFLETIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEV 657
+N N +T Q +S G + DS+E+ S V
Sbjct: 297 EN------------SNSRDTGLSQPRRDSKGDS-----------QEDSKENLSQEESQNV 333
Query: 658 QSVISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRDNSERDD-------- 709
S+ +A +S+ S + +EE+V G+ P + S + D + D
Sbjct: 334 DGPSSESSQEANL--SSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHT 391
Query: 710 ------------VDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQ 757
D E E+ +E+S +D N E L+S +S A+ Q +
Sbjct: 392 LSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQS------HSSSAESQSE 445
Query: 758 E 758
E
Sbjct: 446 E 446
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 49.7 bits (117), Expect = 2e-05
Identities = 91/405 (22%), Positives = 156/405 (38%), Gaps = 71/405 (17%)
Query: 336 DATPPSPRTLLAMQAALLGSSSEEELESENRRQARGRNAPAAVDEGSISPRTLSAIKRAL 395
D + P P+ + LGS + S++ QA +AP +G S + ++ R L
Sbjct: 101 DDSGPGPKDRQEGGNSRLGSDED----SDDTIQASEESAP----QGQDSAQDTTSESREL 152
Query: 396 DDDE--DVKVCAGDDVQ--------TGGPGAEEMRINSSTENSDEGLKVRDGKGIPFTAT 445
D+++ D K GD Q GG E +E DEG++ D + I +
Sbjct: 153 DNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESI--RSE 210
Query: 446 LASSSVNSAEEHVASTNEGREPTDSVPKEQMSLV-HVGTEAFPISDESMIKDRKDRLPLE 504
+S +NSA + E E ++ L+ H + F S S DR +
Sbjct: 211 RGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNN 270
Query: 505 SAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQNELCPYESKFDSSLLSSD 564
+ SD+ N R+ + P + E E L Q+ +
Sbjct: 271 TMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQE-----------------E 313
Query: 565 DETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHEN----FLETIQE 620
+ P+S S +S QE SS ++ E VVS + ++ + ++E ++
Sbjct: 314 SQNVDGPSSESSQEANLSSQENSS---------ESQEEVVSESRGDNPDPTTSYVEDQED 364
Query: 621 QQTTESAGQDLISIPKAVEPME-IDSEESESDGSFIEVQSVISDEELQAEFPETSKPPSE 679
++E +S K+ E DSE SES ++ E E PE S+
Sbjct: 365 SDSSEEDSSHTLSHSKSESREEQADSESSES----------LNFSEESPESPEDENSSSQ 414
Query: 680 QGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKDAEDS 724
+ G + + AES+S + S ++ D + Q++ + EDS
Sbjct: 415 E------GLQSHSSSAESQS---EESHSEEDDSDSQDSSRSKEDS 450
Score = 40.4 bits (93), Expect = 0.010
Identities = 39/167 (23%), Positives = 75/167 (44%), Gaps = 12/167 (7%)
Query: 994 DSFFRLAQQEKEDAKRIKSQRLNRAVTCMLRKEKEAAASEIEAVSVAMEKEFE-----LL 1048
DS L+Q+E ++ S+ A L ++ ++ S+ E VS + + +
Sbjct: 304 DSKENLSQEESQNVDGPSSESSQEA---NLSSQENSSESQEEVVSESRGDNPDPTTSYVE 360
Query: 1049 DKAKRKTQKRGITNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESS 1108
D+ + + ++TL S S R+ +DS+ + F E+ S + SSS++ S
Sbjct: 361 DQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLN-FSEESPESPEDENSSSQEGLQS 419
Query: 1109 SLMNVQRRTAAKEPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDG 1155
+ + ++ + SDSQ+S + K +T S S S++DG
Sbjct: 420 HSSSAESQSEESHSEEDDSDSQDSSRS---KEDSNSTESKSSSEEDG 463
Score = 37.0 bits (84), Expect = 0.11
Identities = 82/403 (20%), Positives = 147/403 (36%), Gaps = 99/403 (24%)
Query: 396 DDDEDVKVCAGDDV---QTGGPGAEEMRINS-----STENSDEGLKVRD-----GKGIPF 442
DDDED +GDD GPG ++ + S E+SD+ ++ + G+
Sbjct: 87 DDDEDD---SGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQ 143
Query: 443 TATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEA-------FPISDESMIK 495
T S +++ E+ V S EG + T E+ V G++ + DE M
Sbjct: 144 DTTSESRELDN-EDRVDSKPEGGDSTQESESEE-HWVGGGSDGESSHGDGSELDDEGMQS 201
Query: 496 DRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQNELCPYESK 555
D + + E R + A G + + + +++ +++LE P
Sbjct: 202 DDPESIRSERGNSRMNSA-----GMKSKESGENSEQANTQDSGGSQLLEH-----PSRKI 251
Query: 556 FDSSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHENFL 615
F S +S +D+ L + +++ V S++ +N N
Sbjct: 252 FRKSRISEEDDRS-------------ELDDNNTMEEVKSDSTEN------------SNSR 286
Query: 616 ETIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSK 675
+T Q +S G + DS+E+ S V S+ +A +S+
Sbjct: 287 DTGLSQPRRDSKGDS-----------QEDSKENLSQEESQNVDGPSSESSQEANL--SSQ 333
Query: 676 PPSEQGEEELVGTREGEAPAESESLLRDNSERDD--------------------VDGEPQ 715
S + +EE+V G+ P + S + D + D D E
Sbjct: 334 ENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESS 393
Query: 716 EAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQE 758
E+ +E+S +D N E L+S +S A+ Q +E
Sbjct: 394 ESLNFSEESPESPEDENSSSQEGLQS------HSSSAESQSEE 430
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 49.7 bits (117), Expect = 2e-05
Identities = 100/475 (21%), Positives = 179/475 (37%), Gaps = 43/475 (9%)
Query: 293 KGIQAKTVAEVDSESLPSSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAAL 352
K I+ +T V + +PS + VK+ EK T+ +P A + + + +
Sbjct: 592 KPIKTETKPSVTEKEVPSKEEPS----PVKAEVAEKQATDVKPKA---AKEKTVKKETKV 644
Query: 353 LGSSSEEELESENRRQARGRN-APAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQT 411
+EE E + A+ + P +E +K+ + +E K +V+
Sbjct: 645 KPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEE--KKEPKKEVKK 702
Query: 412 GGPGAE---EMRINSSTE-NSDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREP 467
P E E++ E +E ++ K +P A +S+ ++ A++ A +
Sbjct: 703 ETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPK---- 758
Query: 468 TDSVPKEQMSLVHVGTEAFPISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASP 527
VPK++ S+ A ++ IK K AV + G + A
Sbjct: 759 ---VPKKEESVKKDSVAAGKPKEKGKIKVIKKEGKAAEAVAA-AVGTGATTAAVMAAAGI 814
Query: 528 TCTNSVSKNETHAEVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVSLQETS 587
+ E ++ +L F+ D TK + L+ET
Sbjct: 815 AAIGPAKELEAERSLMSSPEDLT---KDFEELKAEEVDVTKDIKPQLELIEDEEKLKETE 871
Query: 588 SIVSVPSEAVDNVENVVSFNAKEHENFLETIQEQQTTESAGQDLISIPKAVEPMEI---- 643
P EA V+ + + E+ E TT + P+ +EP+E
Sbjct: 872 -----PVEAY-----VIQKEREVTKGPAESPDEGITTTEGEGECEQTPEELEPVEKQGVD 921
Query: 644 DSEESESDGSFIEVQSVISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRD 703
D E+ E +G+ E S D E +AE E ++ P E GEE + + +P E E +
Sbjct: 922 DIEKFEDEGAGFEESSETGDYEEKAE-TEEAEEPEEDGEEHVCVSASKHSPTEDEESAK- 979
Query: 704 NSERDDVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQE 758
+E D E +E+ +D E D +E+ E +S A + KA+ ++E
Sbjct: 980 -AEADAYIREKRESVASGDDRAEEDMDEAIEKGEAEQSEEEADEED-KAEDAREE 1032
Score = 40.4 bits (93), Expect = 0.010
Identities = 142/679 (20%), Positives = 244/679 (35%), Gaps = 147/679 (21%)
Query: 83 LKKQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAFRSKRDEALPSLTQVRREND 142
+KK+T VK +K+ ++ +K KT +K+ E P +V++E
Sbjct: 638 VKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKK------------EEKPKKEEVKKE-- 683
Query: 143 LYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSSLPPEVKH 202
V +++EEK ++E +KE + +K+ +EE K
Sbjct: 684 --VKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEE----------------------KK 719
Query: 203 EILTDMKEFTKRRRTLFEAMPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEM----NQQH 258
E+ + KE K + L + + S S+ + LK + E V+K+ +
Sbjct: 720 EVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKE-ESVKKDSVAAGKPKE 778
Query: 259 SGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVA-EVDSE-SLPSSSKMHG 316
G I + + EG + V + T+ + GI A A E+++E SL SS +
Sbjct: 779 KGKI-KVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAAIGPAKELEAERSLMSSPEDLT 837
Query: 317 MSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEELESENRRQARGRNAPA 376
F E+LK E+ P+ L L + E + + +
Sbjct: 838 KDF-------EELKAEEVDVTKDIKPQLELIEDEEKLKETEPVEAYVIQKEREVTKGPAE 890
Query: 377 AVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMRINSSTENSDEGLKVRD 436
+ DEG + ++ ++ E V+ DD++ + DEG
Sbjct: 891 SPDEGITTTEGEGECEQTPEELEPVEKQGVDDIE---------------KFEDEG----- 930
Query: 437 GKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEA---FPISDESM 493
A SS E A T E EP E+ HV A P DE
Sbjct: 931 -------AGFEESSETGDYEEKAETEEAEEP------EEDGEEHVCVSASKHSPTEDEES 977
Query: 494 IKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQNELCPYE 553
K D E R S A G E ++ K E EQ E
Sbjct: 978 AKAEADAYIREK---RESVASGDDRAEE------DMDEAIEKGEA-----EQSEE----- 1018
Query: 554 SKFDSSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHEN 613
+D+E K + ++ E P ++ +++V +A + + A+E
Sbjct: 1019 --------EADEEDKAE-DAREEEYEPEKMEAEDYVMAVVDKAAE------AGGAEEQYG 1063
Query: 614 FLETIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPET 673
FL T +Q +S G+ EP +E+ GS E ++ SDEE + + PE
Sbjct: 1064 FLTTPTKQLGAQSPGR---------EPASSIHDETLPGGS--ESEATASDEENREDQPEE 1112
Query: 674 SKPPSEQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKDAEDSLHEWQDINL 733
S + + E +E + ++ RD + E E ++ + +N+
Sbjct: 1113 FTATSGYTQSTI------EISSEPTPMDEMSTPRDVMSDETNNEETESPSQ----EFVNI 1162
Query: 734 EELETLESNLLAQQNSLKA 752
+ ES+L +Q+ S A
Sbjct: 1163 TK---YESSLYSQEYSKPA 1178
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 49.3 bits (116), Expect = 2e-05
Identities = 151/734 (20%), Positives = 282/734 (38%), Gaps = 97/734 (13%)
Query: 85 KQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKT--AFRSKRDEALPSLTQVR---R 139
+ +L R++ + + + E + KT ++T R +++ L Q++ R
Sbjct: 1239 QDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVR 1298
Query: 140 ENDLYVLPPLQEEEKHSSE------------EEDEKEWQER-----MNQKQALQEEFFHN 182
+ +L +LP LQE SE EED K W+ R QK EE+
Sbjct: 1299 KLELDILP-LQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKL 1357
Query: 183 PQAIDIESEDFSSLPPEV---KHEILTDMKEFTKRRRTLFEAMPEESDDFSQYQLKGLLK 239
++ ++ L E+ K EI T + L +++ E+ + K ++
Sbjct: 1358 LSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQN-LIQSLKEDLNKVRTE--KETIQ 1414
Query: 240 KNYLNQHIEHVQKEMNQQHSGHIRRQYEDEGGFLKEVESRRV-VSEDTSHYILIKGIQAK 298
K+ + I+ +K I R+Y+ + LK + + + S +S + + +
Sbjct: 1415 KDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQ 1474
Query: 299 TVAEVDSESLPSSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSE 358
+ E+ + +K + V++ +K +EKE +A +T+ +Q+ L S
Sbjct: 1475 EMQELKETLNQAETKSKSLESQVEN--LQKTLSEKETEARNLQEQTV-QLQSEL--SRLR 1529
Query: 359 EELESENRRQARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEE 418
++L+ ++ + R +E +T AI A + AG Q E
Sbjct: 1530 QDLQDRTTQEEQLRQQITEKEE-----KTRKAIVAA---KSKIAHLAGVKDQLTKENEEL 1581
Query: 419 MRINSSTENSDEGLKVR--------DGKGIPFTATLASSSVNSAEEHVASTNEGREPTDS 470
+ N + + + L VR +G+ + L E H+ +E +EP++
Sbjct: 1582 KQRNGALDQQKDELDVRITALKSQYEGR----ISRLERELREHQERHLEQRDEPQEPSNK 1637
Query: 471 VPKEQMSLVHVGTEAFPISDESMIKDRKD-------RLPLES--------AVVRHSDAPG 515
VP++Q + + P S E I D P+ S A+ + P
Sbjct: 1638 VPEQQRQIT---LKTTPASGERGIASTSDPPTANIKPTPVVSTPSKVTAAAMAGNKSTPR 1694
Query: 516 LPNGRELTPA---SPTCTNSVS-KNETHAEVLEQQNELCPYE--SKFDSSLLSSDDETKC 569
+TPA +PT T + + T E E P E F S +S
Sbjct: 1695 ASIRPMVTPATVTNPTTTPTATVMPTTQVESQEAMQSEGPVEHVPVFGS---TSGSVRST 1751
Query: 570 KPNSASEVIGPV-SLQETSSIVSVPSEAVDNVENVVSFNAKEHENFLETIQ----EQQTT 624
PN + P+ ++Q+ + + + + N + N +E +Q E+ +T
Sbjct: 1752 SPNVQPSISQPILTVQQQTQATAFVQPTQQSHPQIEPANQELSSNIVEVVQSSPVERPST 1811
Query: 625 ESAGQDLIS-IPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKPPSEQGEE 683
+A +S P + P EE +S IE +SD+ ++ P+ K + G E
Sbjct: 1812 STAVFGTVSATPSSSLPKRTREEEEDST---IEASDQVSDDTVEMPLPKKLKSVTPVGTE 1868
Query: 684 ELVGTREGEAPAESESLLRDNSERDDV-DGEPQEAEKDAEDSLHEWQDINLEELETLESN 742
E V E E E+ + + +D + +G Q EDS Q + + +L L+S+
Sbjct: 1869 EEVMAEE-STDGEVETQVYNQDSQDSIGEGVTQGDYTPMEDSEETSQSLQI-DLGPLQSD 1926
Query: 743 LLAQQNSLKAQKQQ 756
QQ + +Q Q
Sbjct: 1927 ---QQTTTSSQDGQ 1937
Score = 31.6 bits (70), Expect = 4.7
Identities = 43/218 (19%), Positives = 91/218 (41%), Gaps = 19/218 (8%)
Query: 595 EAVDNVENVVSFNAKEHENFLETIQEQQTTESAGQ----------DLISIPKAVEPMEID 644
E + N + ++ K+H + +E Q+++ G+ DL+S + E D
Sbjct: 892 ELLKNAQKEIA-TLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVND 950
Query: 645 SEE--SESDGSFIEVQSVISD-EELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLL 701
+E S + + Q++++ EE + + ++ + E L + E + E + L+
Sbjct: 951 LKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKK-LM 1009
Query: 702 RDNSERDDVDGEPQEAEKDAEDSLHEWQ----DINLEELETLESNLLAQQNSLKAQKQQQ 757
E+ ++ + + A + E L E + + E E L+ A N +A++ Q
Sbjct: 1010 EVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQ 1069
Query: 758 ERIAATVTGQMFLESQELLRLFGIPYIQAPMEAEAQCA 795
E+ V Q E + +L + +QA E ++ A
Sbjct: 1070 EQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMA 1107
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 47.4 bits (111), Expect = 8e-05
Identities = 121/727 (16%), Positives = 260/727 (35%), Gaps = 90/727 (12%)
Query: 86 QTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAFRSKRDEALPSLTQVRRENDLYV 145
Q + ++Q +++ + + EK+ +T + ++ E S + + + L
Sbjct: 1153 QVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEE--SKLEKDKASALQE 1210
Query: 146 LPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSSLPPEVKHEIL 205
PL EE+K EEE + R +K+ L EE P+ + E +S P E KH++L
Sbjct: 1211 KKPLPEEKKLIPEEE-----KIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLL 1265
Query: 206 TDMKEFT----------------KRRRTLFEAMPE-------ESDDFSQYQLKG------ 236
+ K+ +T E +P + DD + +K
Sbjct: 1266 KSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPC 1325
Query: 237 LLKKNYLNQHIEHVQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSE--------DTSH 288
K + + E +KE ++ + ++ +G S + S T
Sbjct: 1326 TAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDE 1385
Query: 289 YILIKGIQAKTVAEVDSESLPSS-SKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLA 347
++KG++ + ++ S S PS +K+ + + L EK T P
Sbjct: 1386 KDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPH------ 1439
Query: 348 MQAALLGSSSEEELESENRRQARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGD 407
S E+ + + + Q+ + E I + K D + +
Sbjct: 1440 -------EVSPEQPKDQEKTQSLSETLEITISEEEIK-ESQEERKDTFKKDSQQDIPSSK 1491
Query: 408 DVQTGGPGAEEMRINSSTENSDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREP 467
D + +++ +S E + +P S +S++E+ ++G
Sbjct: 1492 DHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGE 1551
Query: 468 TDSVPKEQMSLVHVGTEAFPISDESMIKDRKDRLPLESAVVRHSDAPG-----LPNGREL 522
+ ++Q+ + +A D+ I+++ + + + + G R L
Sbjct: 1552 EEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRL 1611
Query: 523 TPASPTCTNSVSKNETHAEVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVS 582
T S T S+ ++ ++ + FD S ETK + + V G
Sbjct: 1612 TRKSST---SIDEDAGRRHSWHDED-----DEAFDESPELKYRETKSQESEELVVTGGGG 1663
Query: 583 LQ-----ETSSIVSVPSEAVDNVENVVSFNAKEHENFLETIQEQQTTESAGQDLISI--- 634
L+ E +S ++ A + + + +E E +E++ + S G+ S+
Sbjct: 1664 LRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHAS 1723
Query: 635 --PKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKPPSEQGEEELVGTREGE 692
P + S + +SD S + + P P+ + + E E
Sbjct: 1724 SFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPT------IEDSSEEE 1777
Query: 693 APAESESLLRDNSERDDVDGEPQE--AEKDAEDSLHEWQDINLEELETLESNLLAQQNSL 750
E E LL++ ++ +++ + ++ ++K +D E +T SNL +++
Sbjct: 1778 ELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDAS 1837
Query: 751 KAQKQQQ 757
++ +Q
Sbjct: 1838 PTEELRQ 1844
Score = 44.7 bits (104), Expect = 5e-04
Identities = 100/518 (19%), Positives = 192/518 (37%), Gaps = 76/518 (14%)
Query: 298 KTVAEVDSESLPSSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSS 357
K A + + LP K+ ++S + L EK+P TP + L + +
Sbjct: 1204 KASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKP--TPEDKKLLPEAKTSAPEEQK 1261
Query: 358 EEELESENR---RQARGRNAPAAVDEGSISPRTL-----SAIKRAL--DDDEDVKV---- 403
+ L+S+ + + GR AP V EG P+T S ++L +DD+ K
Sbjct: 1262 HDLLKSQVQIAEEKLEGRVAPKTVQEGK-QPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQ 1320
Query: 404 ----CAG--DDVQTGGPGAEEMRINSSTENSDEGLKVRDGKGIPFTATLASSSVNSA--- 454
C D V+ G E+ S T +S + + +++ SSS+
Sbjct: 1321 PQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSL 1380
Query: 455 -------------EEHVASTNEGREPTDSVPKEQMSLVHVGTEAFPISDESMIKDRKDRL 501
++ + + P+D E L + +A ++DE K K
Sbjct: 1381 IPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADE---KSEKKTQ 1437
Query: 502 PLESAVVRHSDAPGLPNGRELTPA-SPTCTNSVSKNETHAEVLEQQNELCPYESKFDSSL 560
P H +P P +E T + S T ++S+ E + E Q E K
Sbjct: 1438 P-------HEVSPEQPKDQEKTQSLSETLEITISEEE----IKESQEERKDTFKKDSQQD 1486
Query: 561 LSSDDETKCKPNSASEVIGPV----SLQETSSIVSVPSEAVDNVENVVSFNAKEHENFLE 616
+ S + K K ++ S++E+S + P +V S ++ E++
Sbjct: 1487 IPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYK---- 1542
Query: 617 TIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKP 676
Q+ ++ +G++ I K + M D + S S+ DE ++ + E S
Sbjct: 1543 ----QEDSQGSGEEEDFIRKQIIEMSADEDASGSE----------DDEFIRNQLKEISSS 1588
Query: 677 PSEQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKDAEDSLHEWQDINLEEL 736
Q +EE G + A + ++ D+ G + +++ E ++ E
Sbjct: 1589 TESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRET 1648
Query: 737 ETLESNLLAQQNSLKAQKQQQERIAATVTGQMFLESQE 774
++ ES L ++ + + +T+ + ES +
Sbjct: 1649 KSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQ 1686
Score = 32.0 bits (71), Expect = 3.6
Identities = 47/215 (21%), Positives = 88/215 (40%), Gaps = 30/215 (13%)
Query: 980 VLKQLDAQQTQLRIDSFFRLAQQEKEDAKRIKSQRLNRAVTCMLR---KEKEAAASEIEA 1036
VL L+AQ + L + + Q + ++ K Q ++++ L E+E S+ E
Sbjct: 1416 VLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEER 1475
Query: 1037 VSVAMEKEFELLDKAKRKTQK----------RGITNTLEESSSLKRKRLSDSKRKNTCGG 1086
+ + + +K +K R +++EESS + + KR+ + G
Sbjct: 1476 KDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGS 1535
Query: 1087 FLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTSASDS--QNSVKEAPVKNGGAT 1144
+ E S GS E E + +A ++ S D +N +KE ++
Sbjct: 1536 SSSDEYKQEDSQGSGEE--EDFIRKQIIEMSADEDASGSEDDEFIRNQLKEI------SS 1587
Query: 1145 TSSSSDSDDDGGKEKMVLVTARSVFGKKRRKLRRA 1179
++ S ++ GK K +TA GK RR R++
Sbjct: 1588 STESQKKEETKGKGK---ITA----GKHRRLTRKS 1615
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 47.4 bits (111), Expect = 8e-05
Identities = 121/727 (16%), Positives = 260/727 (35%), Gaps = 90/727 (12%)
Query: 86 QTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAFRSKRDEALPSLTQVRRENDLYV 145
Q + ++Q +++ + + EK+ +T + ++ E S + + + L
Sbjct: 1153 QVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEE--SKLEKDKASALQE 1210
Query: 146 LPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSSLPPEVKHEIL 205
PL EE+K EEE + R +K+ L EE P+ + E +S P E KH++L
Sbjct: 1211 KKPLPEEKKLIPEEE-----KIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLL 1265
Query: 206 TDMKEFT----------------KRRRTLFEAMPE-------ESDDFSQYQLKG------ 236
+ K+ +T E +P + DD + +K
Sbjct: 1266 KSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPC 1325
Query: 237 LLKKNYLNQHIEHVQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSE--------DTSH 288
K + + E +KE ++ + ++ +G S + S T
Sbjct: 1326 TAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDE 1385
Query: 289 YILIKGIQAKTVAEVDSESLPSS-SKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLA 347
++KG++ + ++ S S PS +K+ + + L EK T P
Sbjct: 1386 KDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPH------ 1439
Query: 348 MQAALLGSSSEEELESENRRQARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGD 407
S E+ + + + Q+ + E I + K D + +
Sbjct: 1440 -------EVSPEQPKDQEKTQSLSETLEITISEEEIK-ESQEERKDTFKKDSQQDIPSSK 1491
Query: 408 DVQTGGPGAEEMRINSSTENSDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREP 467
D + +++ +S E + +P S +S++E+ ++G
Sbjct: 1492 DHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGE 1551
Query: 468 TDSVPKEQMSLVHVGTEAFPISDESMIKDRKDRLPLESAVVRHSDAPG-----LPNGREL 522
+ ++Q+ + +A D+ I+++ + + + + G R L
Sbjct: 1552 EEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRL 1611
Query: 523 TPASPTCTNSVSKNETHAEVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVS 582
T S T S+ ++ ++ + FD S ETK + + V G
Sbjct: 1612 TRKSST---SIDEDAGRRHSWHDED-----DEAFDESPELKYRETKSQESEELVVTGGGG 1663
Query: 583 LQ-----ETSSIVSVPSEAVDNVENVVSFNAKEHENFLETIQEQQTTESAGQDLISI--- 634
L+ E +S ++ A + + + +E E +E++ + S G+ S+
Sbjct: 1664 LRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHAS 1723
Query: 635 --PKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKPPSEQGEEELVGTREGE 692
P + S + +SD S + + P P+ + + E E
Sbjct: 1724 SFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPT------IEDSSEEE 1777
Query: 693 APAESESLLRDNSERDDVDGEPQE--AEKDAEDSLHEWQDINLEELETLESNLLAQQNSL 750
E E LL++ ++ +++ + ++ ++K +D E +T SNL +++
Sbjct: 1778 ELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDAS 1837
Query: 751 KAQKQQQ 757
++ +Q
Sbjct: 1838 PTEELRQ 1844
Score = 44.7 bits (104), Expect = 5e-04
Identities = 100/518 (19%), Positives = 192/518 (37%), Gaps = 76/518 (14%)
Query: 298 KTVAEVDSESLPSSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSS 357
K A + + LP K+ ++S + L EK+P TP + L + +
Sbjct: 1204 KASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKP--TPEDKKLLPEAKTSAPEEQK 1261
Query: 358 EEELESENR---RQARGRNAPAAVDEGSISPRTL-----SAIKRAL--DDDEDVKV---- 403
+ L+S+ + + GR AP V EG P+T S ++L +DD+ K
Sbjct: 1262 HDLLKSQVQIAEEKLEGRVAPKTVQEGK-QPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQ 1320
Query: 404 ----CAG--DDVQTGGPGAEEMRINSSTENSDEGLKVRDGKGIPFTATLASSSVNSA--- 454
C D V+ G E+ S T +S + + +++ SSS+
Sbjct: 1321 PQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSL 1380
Query: 455 -------------EEHVASTNEGREPTDSVPKEQMSLVHVGTEAFPISDESMIKDRKDRL 501
++ + + P+D E L + +A ++DE K K
Sbjct: 1381 IPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADE---KSEKKTQ 1437
Query: 502 PLESAVVRHSDAPGLPNGRELTPA-SPTCTNSVSKNETHAEVLEQQNELCPYESKFDSSL 560
P H +P P +E T + S T ++S+ E + E Q E K
Sbjct: 1438 P-------HEVSPEQPKDQEKTQSLSETLEITISEEE----IKESQEERKDTFKKDSQQD 1486
Query: 561 LSSDDETKCKPNSASEVIGPV----SLQETSSIVSVPSEAVDNVENVVSFNAKEHENFLE 616
+ S + K K ++ S++E+S + P +V S ++ E++
Sbjct: 1487 IPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYK---- 1542
Query: 617 TIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKP 676
Q+ ++ +G++ I K + M D + S S+ DE ++ + E S
Sbjct: 1543 ----QEDSQGSGEEEDFIRKQIIEMSADEDASGSE----------DDEFIRNQLKEISSS 1588
Query: 677 PSEQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKDAEDSLHEWQDINLEEL 736
Q +EE G + A + ++ D+ G + +++ E ++ E
Sbjct: 1589 TESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRET 1648
Query: 737 ETLESNLLAQQNSLKAQKQQQERIAATVTGQMFLESQE 774
++ ES L ++ + + +T+ + ES +
Sbjct: 1649 KSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQ 1686
Score = 32.0 bits (71), Expect = 3.6
Identities = 47/215 (21%), Positives = 88/215 (40%), Gaps = 30/215 (13%)
Query: 980 VLKQLDAQQTQLRIDSFFRLAQQEKEDAKRIKSQRLNRAVTCMLR---KEKEAAASEIEA 1036
VL L+AQ + L + + Q + ++ K Q ++++ L E+E S+ E
Sbjct: 1416 VLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEER 1475
Query: 1037 VSVAMEKEFELLDKAKRKTQK----------RGITNTLEESSSLKRKRLSDSKRKNTCGG 1086
+ + + +K +K R +++EESS + + KR+ + G
Sbjct: 1476 KDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGS 1535
Query: 1087 FLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTSASDS--QNSVKEAPVKNGGAT 1144
+ E S GS E E + +A ++ S D +N +KE ++
Sbjct: 1536 SSSDEYKQEDSQGSGEE--EDFIRKQIIEMSADEDASGSEDDEFIRNQLKEI------SS 1587
Query: 1145 TSSSSDSDDDGGKEKMVLVTARSVFGKKRRKLRRA 1179
++ S ++ GK K +TA GK RR R++
Sbjct: 1588 STESQKKEETKGKGK---ITA----GKHRRLTRKS 1615
>gi|19923599 calmin [Homo sapiens]
Length = 1002
Score = 46.6 bits (109), Expect = 1e-04
Identities = 118/574 (20%), Positives = 213/574 (37%), Gaps = 71/574 (12%)
Query: 305 SESLPSSSKMHGMSFDVKSSPCEK---LKTEKEPDATPPSPRT---LLAMQAALLGSSSE 358
S SLP +H + K C K L E P S R +LA++ A E
Sbjct: 417 SNSLPIKKTVHFEADTYKDPFCSKNLSLCFEGSPRVAKESLRQDGHVLAVEVA-----EE 471
Query: 359 EELESENRRQARGRNAPAAVD----EGSISPRTLSAIKRALDD----DEDVKVCAGDDVQ 410
+E + E+ + + A D EG+ + S+ AL+ DE+ +
Sbjct: 472 KEQKQESSKIPESSSDKVAGDIFLVEGTNNNSQSSSCNGALESTARHDEESHSLSPPGEN 531
Query: 411 TGGPGAEEMRINSSTENSDEGLKVRDG-KGIPFTATLASSSVNSAEEHVASTNEGREPTD 469
T + ++++N T E L+ D + IP A+ +S + + N+ P +
Sbjct: 532 TVMADSFQIKVNLMTV---EALEEGDYFEAIPLKASKFNSDLIDFASTSQAFNKVPSPHE 588
Query: 470 SVPKEQMSLVHVGTEAFPISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTC 529
+ P E E +KD + + +H E P++P
Sbjct: 589 TKPDEDAEAFENHAEKLGKRSIKSAHKKKDSPEPQVKMDKHEPHQDSGEEAEGCPSAPEE 648
Query: 530 TNSVSKNETHAEVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVSLQETSSI 589
T K E H + + E D L +E P S+ + + +
Sbjct: 649 TPVDKKPEVHEKAKRKSTRPHYEEEGEDDDLQGVGEELSSSPPSSCVSLETLGSHSEEGL 708
Query: 590 VSVPSEAVDNVENVVS--FNAKEHENFLETIQEQQTTESAGQDL------ISIPKAVEPM 641
PS + V + F +E L + E + +DL + P+ P
Sbjct: 709 DFKPSPPLSKVSVIPHDLFYFPHYEVPLAAVLEAYVEDP--EDLKNEEMDLEEPEGYMP- 765
Query: 642 EIDSEESESDGSFIEVQSVISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLL 701
++DS E E+DGS S + E L + + S G VGT PA +
Sbjct: 766 DLDSREEEADGSQSSSSSSVPGESLPSASDQVLY-LSRGG----VGTTPASEPAPL-APH 819
Query: 702 RDNSERDDVDGEPQEAEKDAEDSLHEWQDINLEEL-ETLESNLLAQQNSLKAQKQQQERI 760
D+ +R+ + +P ++ + E NLE + LE N+ + S+ ++K+++ +
Sbjct: 820 EDHQQRETKENDPMDSHQSQESP-------NLENIANPLEENV--TKESISSKKKEKRKH 870
Query: 761 AATVTGQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARH 820
V +F+ +Q+ + E D +D + + T SD ++ RH
Sbjct: 871 VDHVESSLFVAPGS---------VQSSDDLEE-----DSSDYSIPSRTSHSDSSIYLRRH 916
Query: 821 VYRNFFNKNKFVEYYQYVDFHNQLGLD--RNKLI 852
+R+ + +++ YV N LD RN+++
Sbjct: 917 THRSSES-----DHFSYVQLRNAADLDDRRNRIL 945
>gi|39995071 exonuclease 1 isoform b [Homo sapiens]
Length = 846
Score = 46.2 bits (108), Expect = 2e-04
Identities = 41/157 (26%), Positives = 66/157 (42%), Gaps = 7/157 (4%)
Query: 729 QDINLEELETLESNLLAQQNSLKAQKQQQERIAAT----VTGQMFLESQELLRLFGIPYI 784
+++ E ++NLL + L+ K + R T +T M + + R G+ +
Sbjct: 86 KEVERSRRERRQANLLKGKQLLREGKVSEARECFTRSINITHAMAHKVIKAARSQGVDCL 145
Query: 785 QAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFNKNKFVEYYQ-YVDFHNQ 843
AP EA+AQ A L+ IT+DSD+ FG + V +E Q + Q
Sbjct: 146 VAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCRQ 205
Query: 844 LG--LDRNKLINLAYLLGSDYTEGIPTVGCVTAMEIL 878
LG K + L G DY + +G A ++L
Sbjct: 206 LGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACKVL 242
Score = 40.8 bits (94), Expect = 0.008
Identities = 24/96 (25%), Positives = 45/96 (46%), Gaps = 1/96 (1%)
Query: 1 MGVQGLWKLLECSGRQVSPEALEGKILAVDISIWLNQALKGVRDRHGNSIENPHLLTLFH 60
MG+QGL + ++ + + +G+++AVD WL++ ++ +
Sbjct: 1 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM 60
Query: 61 RLCKLLFFR-IRPIFVFDGDAPLLKKQTLVKRRQRK 95
+ +L I+PI VFDG KK+ RR+R+
Sbjct: 61 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERR 96
>gi|39995069 exonuclease 1 isoform a [Homo sapiens]
Length = 803
Score = 46.2 bits (108), Expect = 2e-04
Identities = 41/157 (26%), Positives = 66/157 (42%), Gaps = 7/157 (4%)
Query: 729 QDINLEELETLESNLLAQQNSLKAQKQQQERIAAT----VTGQMFLESQELLRLFGIPYI 784
+++ E ++NLL + L+ K + R T +T M + + R G+ +
Sbjct: 86 KEVERSRRERRQANLLKGKQLLREGKVSEARECFTRSINITHAMAHKVIKAARSQGVDCL 145
Query: 785 QAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFNKNKFVEYYQ-YVDFHNQ 843
AP EA+AQ A L+ IT+DSD+ FG + V +E Q + Q
Sbjct: 146 VAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCRQ 205
Query: 844 LG--LDRNKLINLAYLLGSDYTEGIPTVGCVTAMEIL 878
LG K + L G DY + +G A ++L
Sbjct: 206 LGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACKVL 242
Score = 40.8 bits (94), Expect = 0.008
Identities = 24/96 (25%), Positives = 45/96 (46%), Gaps = 1/96 (1%)
Query: 1 MGVQGLWKLLECSGRQVSPEALEGKILAVDISIWLNQALKGVRDRHGNSIENPHLLTLFH 60
MG+QGL + ++ + + +G+++AVD WL++ ++ +
Sbjct: 1 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM 60
Query: 61 RLCKLLFFR-IRPIFVFDGDAPLLKKQTLVKRRQRK 95
+ +L I+PI VFDG KK+ RR+R+
Sbjct: 61 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERR 96
>gi|18491016 exonuclease 1 isoform b [Homo sapiens]
Length = 846
Score = 46.2 bits (108), Expect = 2e-04
Identities = 41/157 (26%), Positives = 66/157 (42%), Gaps = 7/157 (4%)
Query: 729 QDINLEELETLESNLLAQQNSLKAQKQQQERIAAT----VTGQMFLESQELLRLFGIPYI 784
+++ E ++NLL + L+ K + R T +T M + + R G+ +
Sbjct: 86 KEVERSRRERRQANLLKGKQLLREGKVSEARECFTRSINITHAMAHKVIKAARSQGVDCL 145
Query: 785 QAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFNKNKFVEYYQ-YVDFHNQ 843
AP EA+AQ A L+ IT+DSD+ FG + V +E Q + Q
Sbjct: 146 VAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCRQ 205
Query: 844 LG--LDRNKLINLAYLLGSDYTEGIPTVGCVTAMEIL 878
LG K + L G DY + +G A ++L
Sbjct: 206 LGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACKVL 242
Score = 40.8 bits (94), Expect = 0.008
Identities = 24/96 (25%), Positives = 45/96 (46%), Gaps = 1/96 (1%)
Query: 1 MGVQGLWKLLECSGRQVSPEALEGKILAVDISIWLNQALKGVRDRHGNSIENPHLLTLFH 60
MG+QGL + ++ + + +G+++AVD WL++ ++ +
Sbjct: 1 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM 60
Query: 61 RLCKLLFFR-IRPIFVFDGDAPLLKKQTLVKRRQRK 95
+ +L I+PI VFDG KK+ RR+R+
Sbjct: 61 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERR 96
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 46.2 bits (108), Expect = 2e-04
Identities = 53/229 (23%), Positives = 96/229 (41%), Gaps = 17/229 (7%)
Query: 585 ETSSIVSVPSEAVDNVENVVSFNAKEHENFLETIQEQQTTESAGQDLISIPKAVEPMEID 644
ET S+ ++ +E D E+ E + E QE + ++I +A E + +
Sbjct: 1918 ETESVEALETEGEDEPES----EGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPE 1973
Query: 645 SEESESDGSFIEVQSVISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRDN 704
SE+ E+ +EV++ ++ E Q E + P +E +E + E+ +
Sbjct: 1974 SEDVEA--LEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEG 2031
Query: 705 SERDDVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATV 764
E +V+GE Q+ E DA+ + EE E E+ Q+ +A + ++ A
Sbjct: 2032 EEAQEVEGETQKTEGDAQPESDGVEAPEAEE-EAQEAEGEVQEAEGEAHPESEDVDAQEA 2090
Query: 765 TGQMFLESQELLRLFGIPYIQAP-MEAEAQCAILDLTDQTSGTITDDSD 812
G+ ES+ ++AP E EAQ A +T G +S+
Sbjct: 2091 EGEAQPESEG---------VEAPEAEGEAQKAEGIEAPETEGEAQPESE 2130
Score = 45.4 bits (106), Expect = 3e-04
Identities = 107/515 (20%), Positives = 185/515 (35%), Gaps = 74/515 (14%)
Query: 263 RRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLPSSSKMHGMSFDVK 322
R++ E G EV + ++ TS +TV + P S+ G+
Sbjct: 1695 RKRGEHTDGEAAEVAPGKTHTDPTS---------TRTVQGAEGGLGPGLSQGPGVDEGED 1745
Query: 323 SSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEELESENRRQARGRNAPAAVDEGS 382
++L +K+P + + E E ++ N + G A EG
Sbjct: 1746 GEGSQRLNRDKDPKLGEAEGDAM----------AQEREGKTHNSETSAGSELGEAEQEGE 1795
Query: 383 -ISPRTLSAIKRALDDDE-DVKVCAGDDVQTG----GPGAEEMRINSSTENSDEGLKVRD 436
IS R + + + +D + AG D G G E + EG++ +
Sbjct: 1796 GISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPE 1855
Query: 437 GKGIPFTATLASSSVNSAEEHV-ASTNEGREPTDSVPKEQMSLVHVGTEAFPISD--ESM 493
+G A A E V A EG +S E + E P S+ E+
Sbjct: 1856 AEG---DAQEAEGEAQPESEDVEAPEAEGEAQPES---EDVETPEAEWEVQPESEGAEAP 1909
Query: 494 IKDRKDRLPLESAVVRHSDAPGLPN--GRELTPASPTCTNSVSKNETHAEVLEQQNELCP 551
+++ + ES ++ P G E A + + + +EV+E Q
Sbjct: 1910 EAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQE---- 1965
Query: 552 YESKFDSSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEH 611
+++E + + + V QE SE V+ A E
Sbjct: 1966 -----------AEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVE---------APEA 2005
Query: 612 ENFLETIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIE----VQSVISDEELQ 667
E ++ +E+ ES G + + E E++ E +++G V++ ++EE Q
Sbjct: 2006 EGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQ 2065
Query: 668 AEFPETSKPPSE---QGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEK-DAED 723
E + E + E+ EGEA ESE + E + +GE Q+AE +A +
Sbjct: 2066 EAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGV-----EAPEAEGEAQKAEGIEAPE 2120
Query: 724 SLHEWQDINLEELETLESNLLAQQNSLKAQKQQQE 758
+ E Q E +E E+ AQ S + Q E
Sbjct: 2121 TEGEAQP-ESEGIEAPEAEGEAQPESEGVEAQDAE 2154
Score = 43.9 bits (102), Expect = 0.001
Identities = 92/463 (19%), Positives = 160/463 (34%), Gaps = 59/463 (12%)
Query: 294 GIQAKTVAEVDSESLPSSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAALL 353
G + E + E+ P S V++ E E E +A P S
Sbjct: 1831 GAEGIEAPEAEGEAQPESE-------GVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEA 1883
Query: 354 GSSSEE----ELESENRRQARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDV 409
SE+ E E E + ++ G AP A E ++ A++ +D+ + + G +
Sbjct: 1884 QPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESE---GAEA 1940
Query: 410 QTGGPGAEEMRINSSTENSDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTD 469
Q A+E + E+ + + + P + + + V + +
Sbjct: 1941 QEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDV 2000
Query: 470 SVPKEQMSLVHVGTEAFPISD--ESMIKDRKDRLPLESAVVRHSDAPGLP--NGRELTPA 525
P+ + + EA P SD E+ K + + ++ P +G E A
Sbjct: 2001 EAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEA 2060
Query: 526 SPTCTNSVSKNETHAEVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVSLQE 585
E EV E + E P D+ + + + + A E G E
Sbjct: 2061 EEEA------QEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAE 2114
Query: 586 TSSIVSVPSEAVDNVENVVSFNAK-----------------EHENFLETIQEQQTTESAG 628
EA E + + A+ E + E I+ Q+ E A
Sbjct: 2115 GIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQ 2174
Query: 629 QDLISIPKAVEPMEIDSE-ESESDGSFIEVQSVISDEELQAEFPETSKPPSE---QGEEE 684
+L + VE E + E + ES+G +++ ++ E Q E P +E Q E E
Sbjct: 2175 PEL----EGVEAPEAEGEAQPESEG----IEAPEAEGEAQPELEGVEAPEAEEEAQPEPE 2226
Query: 685 LVGTREGEAPAESESLLRDNSERDDV------DGEPQEAEKDA 721
V T E E A+ ES E+ DG+ +EA + +
Sbjct: 2227 GVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESS 2269
Score = 37.7 bits (86), Expect = 0.066
Identities = 55/231 (23%), Positives = 88/231 (38%), Gaps = 38/231 (16%)
Query: 620 EQQTTESAGQDLISIPKA---VEPMEIDSEESESDGSFIEVQSVISDEELQAEFPET--- 673
+Q +S G + I P+A +P E E++G E + E E PE
Sbjct: 1823 DQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGE 1882
Query: 674 SKPPSE-----QGEEELVGTREG--------EAPAESESLLRDNSERDD----VDGEPQE 716
++P SE + E E+ EG EA E+ES+ +E +D E QE
Sbjct: 1883 AQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQE 1942
Query: 717 AEKDAEDS---------------LHEWQDINLEELETLESNLLAQQNSLKAQKQQQERIA 761
AE+ A+++ E E++E LE + Q+ +AQ + ++ A
Sbjct: 1943 AEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEA 2002
Query: 762 ATVTGQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSD 812
G+M +E Q E E + T +T G +SD
Sbjct: 2003 PEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESD 2053
Score = 31.2 bits (69), Expect = 6.1
Identities = 70/345 (20%), Positives = 113/345 (32%), Gaps = 51/345 (14%)
Query: 149 LQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSSLPPEVKHEILTDM 208
+QE E+ + E D E Q + ++A + E D + E PE + E
Sbjct: 2009 MQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAE 2068
Query: 209 KEFTKRRRTLFEAMPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHSGHIRRQYED 268
E + EA P ES+D + +G Q E
Sbjct: 2069 GEVQEAEG---EAHP-ESEDVDAQEAEG--------------------------EAQPES 2098
Query: 269 EGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLPSSSKMHGMSFDVKSSP-CE 327
EG E E +E GI+A E + E+ P S + + ++ P E
Sbjct: 2099 EGVEAPEAEGEAQKAE---------GIEA---PETEGEAQPESEGIEAPEAEGEAQPESE 2146
Query: 328 KLKTEKEPDATPPSPRTLLAMQAALLGSSSEEELESENRRQARGRNAPAAVDEGSISPRT 387
++ + P + A +A ++ ELE +A G P + EG +P
Sbjct: 2147 GVEAQDAEGEAQPESEGIEAQEAE---EEAQPELEGVEAPEAEGEAQPES--EGIEAPEA 2201
Query: 388 LSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMRINSSTENSDEGLKVRDGKGIPFTATLA 447
+ L+ E + A ++ Q G E + EG + KG P +L
Sbjct: 2202 EGEAQPELEGVEAPE--AEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSP-QVSLG 2258
Query: 448 SSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFPISDES 492
A E + E R P G++ P S +
Sbjct: 2259 DGQSEEASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPSSSRA 2303
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 45.1 bits (105), Expect = 4e-04
Identities = 92/447 (20%), Positives = 161/447 (36%), Gaps = 52/447 (11%)
Query: 327 EKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEELESENRRQARGRNAPAAVDEGSISPR 386
E ++ K D L A+ L S EE+ E+ ++ A +E +
Sbjct: 455 EIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKE---EEPEAEEEEVAAKKS 511
Query: 387 TLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMRINSSTENSDEGLKVRDGKGIPFTATL 446
+ A + ++E K + + G EE + ++ ++EG ++G
Sbjct: 512 PVKATAPEVKEEEGEK-----EEEEGQEEEEEEDEGAKSDQAEEGGSEKEG--------- 557
Query: 447 ASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFPISDESMIKDRKDRLPLESA 506
SS E+ T E ++ KE+ + E + E ++ D K P E A
Sbjct: 558 -SSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEV--ATKEELVADAKVEKP-EKA 613
Query: 507 VVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQNELCPYESKFDSSLLSSDDE 566
+P G+ P SP E + P E K S + S E
Sbjct: 614 KSPVPKSPVEEKGKSPVPKSPV-----------EEKGKSPVPKSPVEEKGKSPVPKSPVE 662
Query: 567 TKCK-PNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHENFLETIQEQQTTE 625
K K P S S PV + S + P E + V KE E E++ E
Sbjct: 663 EKGKSPVSKS----PVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEE-------EKEVKE 711
Query: 626 SAGQDLISI----PKAVEPMEIDSEESESDGSFIEVQSVISDEE--LQAEFPETSKPPSE 679
+ ++ + PK V P + +E + + EV ++ + L+ E E KP +
Sbjct: 712 APKEEKVEKKEEKPKDV-PEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQ 770
Query: 680 QGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKDAEDSLHEWQDINLEELETL 739
+ E+E G G S+ + + + D E +++ E E EE +
Sbjct: 771 EKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVV 830
Query: 740 ESNL-LAQQNSLKAQKQQQERIAATVT 765
+ L L+ + K + +E++ T T
Sbjct: 831 TNGLDLSPADEKKGGDKSEEKVVVTKT 857
Score = 36.6 bits (83), Expect = 0.15
Identities = 29/141 (20%), Positives = 64/141 (45%), Gaps = 19/141 (13%)
Query: 634 IPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKPPSEQ------GEEELVG 687
+ + +E +++ E+SE + + + EEL E K +E+ EEE V
Sbjct: 453 VEEIIEETKVEDEKSEMEEALTAIT-----EELAVSMKEEKKEAAEEKEEEPEAEEEEVA 507
Query: 688 TREGEAPAESESLLRDNSERDDVDGEPQEAEKD-------AEDSLHEWQ-DINLEELETL 739
++ A + + + E+++ +G+ +E E+D AE+ E + EE E
Sbjct: 508 AKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQE 567
Query: 740 ESNLLAQQNSLKAQKQQQERI 760
E A+ +A+ ++++++
Sbjct: 568 EGETEAEAEGEEAEAKEEKKV 588
Score = 33.1 bits (74), Expect = 1.6
Identities = 38/164 (23%), Positives = 70/164 (42%), Gaps = 19/164 (11%)
Query: 568 KCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHENFLETIQEQQTTESA 627
K + E+I +++ S + EA+ + ++ + KE + E +E++ A
Sbjct: 447 KVQHKFVEEIIEETKVEDEKSEME---EALTAITEELAVSMKEEKK--EAAEEKEEEPEA 501
Query: 628 GQDLISIPK------AVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKPPS--- 678
++ ++ K A E E + E+ E +G E + + QAE + K S
Sbjct: 502 EEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEK 561
Query: 679 EQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKDAE 722
E+GE+E EGE AE+E + E V+ + +E E
Sbjct: 562 EEGEQE-----EGETEAEAEGEEAEAKEEKKVEEKSEEVATKEE 600
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 45.1 bits (105), Expect = 4e-04
Identities = 92/447 (20%), Positives = 161/447 (36%), Gaps = 52/447 (11%)
Query: 327 EKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEELESENRRQARGRNAPAAVDEGSISPR 386
E ++ K D L A+ L S EE+ E+ ++ A +E +
Sbjct: 79 EIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKE---EEPEAEEEEVAAKKS 135
Query: 387 TLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMRINSSTENSDEGLKVRDGKGIPFTATL 446
+ A + ++E K + + G EE + ++ ++EG ++G
Sbjct: 136 PVKATAPEVKEEEGEK-----EEEEGQEEEEEEDEGAKSDQAEEGGSEKEG--------- 181
Query: 447 ASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFPISDESMIKDRKDRLPLESA 506
SS E+ T E ++ KE+ + E + E ++ D K P E A
Sbjct: 182 -SSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEV--ATKEELVADAKVEKP-EKA 237
Query: 507 VVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQNELCPYESKFDSSLLSSDDE 566
+P G+ P SP E + P E K S + S E
Sbjct: 238 KSPVPKSPVEEKGKSPVPKSPV-----------EEKGKSPVPKSPVEEKGKSPVPKSPVE 286
Query: 567 TKCK-PNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHENFLETIQEQQTTE 625
K K P S S PV + S + P E + V KE E E++ E
Sbjct: 287 EKGKSPVSKS----PVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEE-------EKEVKE 335
Query: 626 SAGQDLISI----PKAVEPMEIDSEESESDGSFIEVQSVISDEE--LQAEFPETSKPPSE 679
+ ++ + PK V P + +E + + EV ++ + L+ E E KP +
Sbjct: 336 APKEEKVEKKEEKPKDV-PEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQ 394
Query: 680 QGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKDAEDSLHEWQDINLEELETL 739
+ E+E G G S+ + + + D E +++ E E EE +
Sbjct: 395 EKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVV 454
Query: 740 ESNL-LAQQNSLKAQKQQQERIAATVT 765
+ L L+ + K + +E++ T T
Sbjct: 455 TNGLDLSPADEKKGGDKSEEKVVVTKT 481
Score = 36.6 bits (83), Expect = 0.15
Identities = 29/141 (20%), Positives = 64/141 (45%), Gaps = 19/141 (13%)
Query: 634 IPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKPPSEQ------GEEELVG 687
+ + +E +++ E+SE + + + EEL E K +E+ EEE V
Sbjct: 77 VEEIIEETKVEDEKSEMEEALTAIT-----EELAVSMKEEKKEAAEEKEEEPEAEEEEVA 131
Query: 688 TREGEAPAESESLLRDNSERDDVDGEPQEAEKD-------AEDSLHEWQ-DINLEELETL 739
++ A + + + E+++ +G+ +E E+D AE+ E + EE E
Sbjct: 132 AKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQE 191
Query: 740 ESNLLAQQNSLKAQKQQQERI 760
E A+ +A+ ++++++
Sbjct: 192 EGETEAEAEGEEAEAKEEKKV 212
Score = 33.1 bits (74), Expect = 1.6
Identities = 38/164 (23%), Positives = 70/164 (42%), Gaps = 19/164 (11%)
Query: 568 KCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHENFLETIQEQQTTESA 627
K + E+I +++ S + EA+ + ++ + KE + E +E++ A
Sbjct: 71 KVQHKFVEEIIEETKVEDEKSEME---EALTAITEELAVSMKEEKK--EAAEEKEEEPEA 125
Query: 628 GQDLISIPK------AVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKPPS--- 678
++ ++ K A E E + E+ E +G E + + QAE + K S
Sbjct: 126 EEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEK 185
Query: 679 EQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKDAE 722
E+GE+E EGE AE+E + E V+ + +E E
Sbjct: 186 EEGEQE-----EGETEAEAEGEEAEAKEEKKVEEKSEEVATKEE 224
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 44.7 bits (104), Expect = 5e-04
Identities = 128/710 (18%), Positives = 276/710 (38%), Gaps = 84/710 (11%)
Query: 79 DAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLK---TFLKRQAIKTAFRSKRDEALPSLT 135
D+ L +++ LV+ R+ R+ E++L +F K A K + +
Sbjct: 1903 DSELERQKGLVEDTLRQ------RRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE 1956
Query: 136 QVRRENDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSS 195
R + L ++ + + EE +E +ER+ + A +EE +A E E +
Sbjct: 1957 DTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKA 2016
Query: 196 LPPEVKHEILTDMKEFTKRRRTLFEA------MPEESDDFSQYQLKGLLKKNYLNQHIEH 249
E + +E ++ + EA E++ F+ Q K+ L Q ++
Sbjct: 2017 KVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ-----KEQELQQTLQQ 2071
Query: 250 VQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLP 309
Q ++Q +R + E +E E RV +E + Q++ E ++E L
Sbjct: 2072 EQSVLDQ-----LRGEAEAARRAAEEAEEARVQAER-------EAAQSRRQVE-EAERLK 2118
Query: 310 SSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAAL-LGSSSEEELESENRRQ 368
S++ + + EKL+ E E +A R A QAAL +++ E+E +
Sbjct: 2119 QSAEEQAQARAQAQAAAEKLRKEAEQEAA----RRAQAEQAALRQKQAADAEMEKHKKFA 2174
Query: 369 ARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQ-TGGPGAEEMRINSSTEN 427
+ A V++ L+ ++ L++ + K +++Q E R S E
Sbjct: 2175 EQTLRQKAQVEQ------ELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEE 2228
Query: 428 SDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFP 487
++V+ + A + AE + + +E + V EA
Sbjct: 2229 ELFSVRVQMEELSKLKARI------EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR 2282
Query: 488 ISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQN 547
+S + R +L E + + A ++ ++ + AE+L+QQ
Sbjct: 2283 LSVAAQEAARLRQLAEEDLAQQRALA------EKMLKEKMQAVQEATRLKAEAELLQQQK 2336
Query: 548 ELCPYESKFDSSLLSSDDETKCKPNSASEVIG-----------PVSLQETSSIVSVPSEA 596
EL +++ +D+ + A E G + + + + +
Sbjct: 2337 ELAQEQAR-----RLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAE 2391
Query: 597 VDNVENVVSFNAKEHENFLETIQEQ-QTTESAGQDLISIPKAVEPMEIDSEESESDGSFI 655
+ + +A+ E I E+ TE A Q+ +++ V+ +EI ++S+ D
Sbjct: 2392 MSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL---VQTLEIQRQQSDHDAE-- 2446
Query: 656 EVQSVISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRD-NSERDDVDGEP 714
++ I++ E + E + + EE+ ++ + E+++L + SE+D +
Sbjct: 2447 RLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL---- 2502
Query: 715 QEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATV 764
+ E+ E + + + +E+ + QQ + +Q+++R+ A++
Sbjct: 2503 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASM 2552
Score = 35.8 bits (81), Expect = 0.25
Identities = 146/781 (18%), Positives = 283/781 (36%), Gaps = 115/781 (14%)
Query: 85 KQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAF--RSKRDEALPSLTQVRREND 142
+Q V+R ++ +A ++++ E L++ A KTA RS ++E + ++ Q+R E +
Sbjct: 1553 RQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV-AVAQLREEAE 1611
Query: 143 LYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSSLPPEVKH 202
+ E E + + WQ + N+ L+ + Q + + E +
Sbjct: 1612 RRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAER 1671
Query: 203 EILTDMKEFTKRRRTLFEAMPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHSGHI 262
E RRR E + ++ +L+ K+ L + + Q+ I
Sbjct: 1672 EA---------RRRGKAEEQAVRQRELAEQELE---KQRQLAEGTAQQRLAAEQEL---I 1716
Query: 263 RRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLPSSSKMHGMSFDVK 322
R + E E G + R+++ E+ + + E+++E ++M +
Sbjct: 1717 RLRAETEQG----EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL---- 1768
Query: 323 SSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEE-----LESENRRQARGRNAPAA 377
K + E+E +T + L +A +EE L E +RQ + AA
Sbjct: 1769 ---ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAA 1825
Query: 378 VDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMRINSSTENSDEGLKVRDG 437
+ R L+ A+ + +K A ++ AE R+ E DE + R
Sbjct: 1826 RQRAE-AERVLAEKLAAIGEATRLKTEA--EIALKEKEAENERLRRLAE--DEAFQRRR- 1879
Query: 438 KGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFPISDESMIKDR 497
A+ EE +A R+ +DS + Q LV +E ++ +
Sbjct: 1880 -----LEEQAAQHKADIEERLAQL---RKASDSELERQKGLVEDTLRQRRQVEEEILALK 1931
Query: 498 KDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQNELCPYESKFD 557
E A ++ L GR + A T SK + E Q+ E +
Sbjct: 1932 AS---FEKAAAGKAELE-LELGRIRSNAEDTLR---SKEQAELEAARQRQLAAEEERR-- 1982
Query: 558 SSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHENF-LE 616
+ E + + + A+E +E + E V+ ++ V + E E
Sbjct: 1983 ----RREAEERVQKSLAAE-------EEAARQRKAALEEVERLKAKVEEARRLRERAEQE 2031
Query: 617 TIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKP 676
+ ++ Q + A Q + + + +E E + + QSV+ +AE +
Sbjct: 2032 SARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAE 2091
Query: 677 PSE----QGEEELVGTR-------------------EGEAPAESESLLRDNS-------- 705
+E Q E E +R +A A +E L ++
Sbjct: 2092 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2151
Query: 706 -------ERDDVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQE 758
++ D E ++ +K AE +L + + +EL TL L + ++ +
Sbjct: 2152 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVE-QELTTLRLQLEETDHQKNLLDEELQ 2210
Query: 759 RIAATVTGQMFLESQELLRLFGI-------PYIQAPMEAEAQCAILDLTDQTSGTITDDS 811
R+ A T SQ LF + ++A +EAE + IL D T + +++
Sbjct: 2211 RLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEA 2270
Query: 812 D 812
+
Sbjct: 2271 E 2271
Score = 32.3 bits (72), Expect = 2.8
Identities = 39/135 (28%), Positives = 65/135 (48%), Gaps = 14/135 (10%)
Query: 636 KAVEPMEIDSEESESDGSFIEV------QSVISDEELQAEFPETSKPPS-EQGEEELVGT 688
+A+E + + +EE+E EV Q + + AE SK S + +L +
Sbjct: 1536 QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERS 1595
Query: 689 REGEAPAESESLLRDNSERD-DVDGEPQEAEKDAEDSLHEWQDINLEELE-TLESNLLAQ 746
+ E A ++ LR+ +ER E + A ++AE L WQ E L L++ +AQ
Sbjct: 1596 LQEEHVAVAQ--LREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQ 1653
Query: 747 QNSL---KAQKQQQE 758
Q SL +A+KQ++E
Sbjct: 1654 QKSLAQAEAEKQKEE 1668
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 44.7 bits (104), Expect = 5e-04
Identities = 128/710 (18%), Positives = 276/710 (38%), Gaps = 84/710 (11%)
Query: 79 DAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLK---TFLKRQAIKTAFRSKRDEALPSLT 135
D+ L +++ LV+ R+ R+ E++L +F K A K + +
Sbjct: 1907 DSELERQKGLVEDTLRQ------RRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE 1960
Query: 136 QVRRENDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSS 195
R + L ++ + + EE +E +ER+ + A +EE +A E E +
Sbjct: 1961 DTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKA 2020
Query: 196 LPPEVKHEILTDMKEFTKRRRTLFEA------MPEESDDFSQYQLKGLLKKNYLNQHIEH 249
E + +E ++ + EA E++ F+ Q K+ L Q ++
Sbjct: 2021 KVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ-----KEQELQQTLQQ 2075
Query: 250 VQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLP 309
Q ++Q +R + E +E E RV +E + Q++ E ++E L
Sbjct: 2076 EQSVLDQ-----LRGEAEAARRAAEEAEEARVQAER-------EAAQSRRQVE-EAERLK 2122
Query: 310 SSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAAL-LGSSSEEELESENRRQ 368
S++ + + EKL+ E E +A R A QAAL +++ E+E +
Sbjct: 2123 QSAEEQAQARAQAQAAAEKLRKEAEQEAA----RRAQAEQAALRQKQAADAEMEKHKKFA 2178
Query: 369 ARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQ-TGGPGAEEMRINSSTEN 427
+ A V++ L+ ++ L++ + K +++Q E R S E
Sbjct: 2179 EQTLRQKAQVEQ------ELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEE 2232
Query: 428 SDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFP 487
++V+ + A + AE + + +E + V EA
Sbjct: 2233 ELFSVRVQMEELSKLKARI------EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR 2286
Query: 488 ISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQN 547
+S + R +L E + + A ++ ++ + AE+L+QQ
Sbjct: 2287 LSVAAQEAARLRQLAEEDLAQQRALA------EKMLKEKMQAVQEATRLKAEAELLQQQK 2340
Query: 548 ELCPYESKFDSSLLSSDDETKCKPNSASEVIG-----------PVSLQETSSIVSVPSEA 596
EL +++ +D+ + A E G + + + + +
Sbjct: 2341 ELAQEQAR-----RLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAE 2395
Query: 597 VDNVENVVSFNAKEHENFLETIQEQ-QTTESAGQDLISIPKAVEPMEIDSEESESDGSFI 655
+ + +A+ E I E+ TE A Q+ +++ V+ +EI ++S+ D
Sbjct: 2396 MSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL---VQTLEIQRQQSDHDAE-- 2450
Query: 656 EVQSVISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRD-NSERDDVDGEP 714
++ I++ E + E + + EE+ ++ + E+++L + SE+D +
Sbjct: 2451 RLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL---- 2506
Query: 715 QEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATV 764
+ E+ E + + + +E+ + QQ + +Q+++R+ A++
Sbjct: 2507 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASM 2556
Score = 35.8 bits (81), Expect = 0.25
Identities = 146/781 (18%), Positives = 283/781 (36%), Gaps = 115/781 (14%)
Query: 85 KQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAF--RSKRDEALPSLTQVRREND 142
+Q V+R ++ +A ++++ E L++ A KTA RS ++E + ++ Q+R E +
Sbjct: 1557 RQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV-AVAQLREEAE 1615
Query: 143 LYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSSLPPEVKH 202
+ E E + + WQ + N+ L+ + Q + + E +
Sbjct: 1616 RRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAER 1675
Query: 203 EILTDMKEFTKRRRTLFEAMPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHSGHI 262
E RRR E + ++ +L+ K+ L + + Q+ I
Sbjct: 1676 EA---------RRRGKAEEQAVRQRELAEQELE---KQRQLAEGTAQQRLAAEQEL---I 1720
Query: 263 RRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLPSSSKMHGMSFDVK 322
R + E E G + R+++ E+ + + E+++E ++M +
Sbjct: 1721 RLRAETEQG----EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL---- 1772
Query: 323 SSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEE-----LESENRRQARGRNAPAA 377
K + E+E +T + L +A +EE L E +RQ + AA
Sbjct: 1773 ---ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAA 1829
Query: 378 VDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMRINSSTENSDEGLKVRDG 437
+ R L+ A+ + +K A ++ AE R+ E DE + R
Sbjct: 1830 RQRAE-AERVLAEKLAAIGEATRLKTEA--EIALKEKEAENERLRRLAE--DEAFQRRR- 1883
Query: 438 KGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFPISDESMIKDR 497
A+ EE +A R+ +DS + Q LV +E ++ +
Sbjct: 1884 -----LEEQAAQHKADIEERLAQL---RKASDSELERQKGLVEDTLRQRRQVEEEILALK 1935
Query: 498 KDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQNELCPYESKFD 557
E A ++ L GR + A T SK + E Q+ E +
Sbjct: 1936 AS---FEKAAAGKAELE-LELGRIRSNAEDTLR---SKEQAELEAARQRQLAAEEERR-- 1986
Query: 558 SSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHENF-LE 616
+ E + + + A+E +E + E V+ ++ V + E E
Sbjct: 1987 ----RREAEERVQKSLAAE-------EEAARQRKAALEEVERLKAKVEEARRLRERAEQE 2035
Query: 617 TIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKP 676
+ ++ Q + A Q + + + +E E + + QSV+ +AE +
Sbjct: 2036 SARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAE 2095
Query: 677 PSE----QGEEELVGTR-------------------EGEAPAESESLLRDNS-------- 705
+E Q E E +R +A A +E L ++
Sbjct: 2096 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2155
Query: 706 -------ERDDVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQE 758
++ D E ++ +K AE +L + + +EL TL L + ++ +
Sbjct: 2156 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVE-QELTTLRLQLEETDHQKNLLDEELQ 2214
Query: 759 RIAATVTGQMFLESQELLRLFGI-------PYIQAPMEAEAQCAILDLTDQTSGTITDDS 811
R+ A T SQ LF + ++A +EAE + IL D T + +++
Sbjct: 2215 RLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEA 2274
Query: 812 D 812
+
Sbjct: 2275 E 2275
Score = 32.3 bits (72), Expect = 2.8
Identities = 39/135 (28%), Positives = 65/135 (48%), Gaps = 14/135 (10%)
Query: 636 KAVEPMEIDSEESESDGSFIEV------QSVISDEELQAEFPETSKPPS-EQGEEELVGT 688
+A+E + + +EE+E EV Q + + AE SK S + +L +
Sbjct: 1540 QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERS 1599
Query: 689 REGEAPAESESLLRDNSERD-DVDGEPQEAEKDAEDSLHEWQDINLEELE-TLESNLLAQ 746
+ E A ++ LR+ +ER E + A ++AE L WQ E L L++ +AQ
Sbjct: 1600 LQEEHVAVAQ--LREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQ 1657
Query: 747 QNSL---KAQKQQQE 758
Q SL +A+KQ++E
Sbjct: 1658 QKSLAQAEAEKQKEE 1672
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 44.7 bits (104), Expect = 5e-04
Identities = 128/710 (18%), Positives = 276/710 (38%), Gaps = 84/710 (11%)
Query: 79 DAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLK---TFLKRQAIKTAFRSKRDEALPSLT 135
D+ L +++ LV+ R+ R+ E++L +F K A K + +
Sbjct: 1903 DSELERQKGLVEDTLRQ------RRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE 1956
Query: 136 QVRRENDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSS 195
R + L ++ + + EE +E +ER+ + A +EE +A E E +
Sbjct: 1957 DTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKA 2016
Query: 196 LPPEVKHEILTDMKEFTKRRRTLFEA------MPEESDDFSQYQLKGLLKKNYLNQHIEH 249
E + +E ++ + EA E++ F+ Q K+ L Q ++
Sbjct: 2017 KVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ-----KEQELQQTLQQ 2071
Query: 250 VQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLP 309
Q ++Q +R + E +E E RV +E + Q++ E ++E L
Sbjct: 2072 EQSVLDQ-----LRGEAEAARRAAEEAEEARVQAER-------EAAQSRRQVE-EAERLK 2118
Query: 310 SSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAAL-LGSSSEEELESENRRQ 368
S++ + + EKL+ E E +A R A QAAL +++ E+E +
Sbjct: 2119 QSAEEQAQARAQAQAAAEKLRKEAEQEAA----RRAQAEQAALRQKQAADAEMEKHKKFA 2174
Query: 369 ARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQ-TGGPGAEEMRINSSTEN 427
+ A V++ L+ ++ L++ + K +++Q E R S E
Sbjct: 2175 EQTLRQKAQVEQ------ELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEE 2228
Query: 428 SDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFP 487
++V+ + A + AE + + +E + V EA
Sbjct: 2229 ELFSVRVQMEELSKLKARI------EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR 2282
Query: 488 ISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQN 547
+S + R +L E + + A ++ ++ + AE+L+QQ
Sbjct: 2283 LSVAAQEAARLRQLAEEDLAQQRALA------EKMLKEKMQAVQEATRLKAEAELLQQQK 2336
Query: 548 ELCPYESKFDSSLLSSDDETKCKPNSASEVIG-----------PVSLQETSSIVSVPSEA 596
EL +++ +D+ + A E G + + + + +
Sbjct: 2337 ELAQEQAR-----RLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAE 2391
Query: 597 VDNVENVVSFNAKEHENFLETIQEQ-QTTESAGQDLISIPKAVEPMEIDSEESESDGSFI 655
+ + +A+ E I E+ TE A Q+ +++ V+ +EI ++S+ D
Sbjct: 2392 MSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL---VQTLEIQRQQSDHDAE-- 2446
Query: 656 EVQSVISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRD-NSERDDVDGEP 714
++ I++ E + E + + EE+ ++ + E+++L + SE+D +
Sbjct: 2447 RLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL---- 2502
Query: 715 QEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATV 764
+ E+ E + + + +E+ + QQ + +Q+++R+ A++
Sbjct: 2503 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASM 2552
Score = 35.8 bits (81), Expect = 0.25
Identities = 146/781 (18%), Positives = 283/781 (36%), Gaps = 115/781 (14%)
Query: 85 KQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAF--RSKRDEALPSLTQVRREND 142
+Q V+R ++ +A ++++ E L++ A KTA RS ++E + ++ Q+R E +
Sbjct: 1553 RQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV-AVAQLREEAE 1611
Query: 143 LYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSSLPPEVKH 202
+ E E + + WQ + N+ L+ + Q + + E +
Sbjct: 1612 RRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAER 1671
Query: 203 EILTDMKEFTKRRRTLFEAMPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHSGHI 262
E RRR E + ++ +L+ K+ L + + Q+ I
Sbjct: 1672 EA---------RRRGKAEEQAVRQRELAEQELE---KQRQLAEGTAQQRLAAEQEL---I 1716
Query: 263 RRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLPSSSKMHGMSFDVK 322
R + E E G + R+++ E+ + + E+++E ++M +
Sbjct: 1717 RLRAETEQG----EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL---- 1768
Query: 323 SSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEE-----LESENRRQARGRNAPAA 377
K + E+E +T + L +A +EE L E +RQ + AA
Sbjct: 1769 ---ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAA 1825
Query: 378 VDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMRINSSTENSDEGLKVRDG 437
+ R L+ A+ + +K A ++ AE R+ E DE + R
Sbjct: 1826 RQRAE-AERVLAEKLAAIGEATRLKTEA--EIALKEKEAENERLRRLAE--DEAFQRRR- 1879
Query: 438 KGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFPISDESMIKDR 497
A+ EE +A R+ +DS + Q LV +E ++ +
Sbjct: 1880 -----LEEQAAQHKADIEERLAQL---RKASDSELERQKGLVEDTLRQRRQVEEEILALK 1931
Query: 498 KDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQNELCPYESKFD 557
E A ++ L GR + A T SK + E Q+ E +
Sbjct: 1932 AS---FEKAAAGKAELE-LELGRIRSNAEDTLR---SKEQAELEAARQRQLAAEEERR-- 1982
Query: 558 SSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHENF-LE 616
+ E + + + A+E +E + E V+ ++ V + E E
Sbjct: 1983 ----RREAEERVQKSLAAE-------EEAARQRKAALEEVERLKAKVEEARRLRERAEQE 2031
Query: 617 TIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKP 676
+ ++ Q + A Q + + + +E E + + QSV+ +AE +
Sbjct: 2032 SARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAE 2091
Query: 677 PSE----QGEEELVGTR-------------------EGEAPAESESLLRDNS-------- 705
+E Q E E +R +A A +E L ++
Sbjct: 2092 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2151
Query: 706 -------ERDDVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQE 758
++ D E ++ +K AE +L + + +EL TL L + ++ +
Sbjct: 2152 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVE-QELTTLRLQLEETDHQKNLLDEELQ 2210
Query: 759 RIAATVTGQMFLESQELLRLFGI-------PYIQAPMEAEAQCAILDLTDQTSGTITDDS 811
R+ A T SQ LF + ++A +EAE + IL D T + +++
Sbjct: 2211 RLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEA 2270
Query: 812 D 812
+
Sbjct: 2271 E 2271
Score = 32.3 bits (72), Expect = 2.8
Identities = 39/135 (28%), Positives = 65/135 (48%), Gaps = 14/135 (10%)
Query: 636 KAVEPMEIDSEESESDGSFIEV------QSVISDEELQAEFPETSKPPS-EQGEEELVGT 688
+A+E + + +EE+E EV Q + + AE SK S + +L +
Sbjct: 1536 QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERS 1595
Query: 689 REGEAPAESESLLRDNSERD-DVDGEPQEAEKDAEDSLHEWQDINLEELE-TLESNLLAQ 746
+ E A ++ LR+ +ER E + A ++AE L WQ E L L++ +AQ
Sbjct: 1596 LQEEHVAVAQ--LREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQ 1653
Query: 747 QNSL---KAQKQQQE 758
Q SL +A+KQ++E
Sbjct: 1654 QKSLAQAEAEKQKEE 1668
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 44.7 bits (104), Expect = 5e-04
Identities = 128/710 (18%), Positives = 276/710 (38%), Gaps = 84/710 (11%)
Query: 79 DAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLK---TFLKRQAIKTAFRSKRDEALPSLT 135
D+ L +++ LV+ R+ R+ E++L +F K A K + +
Sbjct: 1871 DSELERQKGLVEDTLRQ------RRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE 1924
Query: 136 QVRRENDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSS 195
R + L ++ + + EE +E +ER+ + A +EE +A E E +
Sbjct: 1925 DTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKA 1984
Query: 196 LPPEVKHEILTDMKEFTKRRRTLFEA------MPEESDDFSQYQLKGLLKKNYLNQHIEH 249
E + +E ++ + EA E++ F+ Q K+ L Q ++
Sbjct: 1985 KVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ-----KEQELQQTLQQ 2039
Query: 250 VQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLP 309
Q ++Q +R + E +E E RV +E + Q++ E ++E L
Sbjct: 2040 EQSVLDQ-----LRGEAEAARRAAEEAEEARVQAER-------EAAQSRRQVE-EAERLK 2086
Query: 310 SSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAAL-LGSSSEEELESENRRQ 368
S++ + + EKL+ E E +A R A QAAL +++ E+E +
Sbjct: 2087 QSAEEQAQARAQAQAAAEKLRKEAEQEAA----RRAQAEQAALRQKQAADAEMEKHKKFA 2142
Query: 369 ARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQ-TGGPGAEEMRINSSTEN 427
+ A V++ L+ ++ L++ + K +++Q E R S E
Sbjct: 2143 EQTLRQKAQVEQ------ELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEE 2196
Query: 428 SDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFP 487
++V+ + A + AE + + +E + V EA
Sbjct: 2197 ELFSVRVQMEELSKLKARI------EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR 2250
Query: 488 ISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQN 547
+S + R +L E + + A ++ ++ + AE+L+QQ
Sbjct: 2251 LSVAAQEAARLRQLAEEDLAQQRALA------EKMLKEKMQAVQEATRLKAEAELLQQQK 2304
Query: 548 ELCPYESKFDSSLLSSDDETKCKPNSASEVIG-----------PVSLQETSSIVSVPSEA 596
EL +++ +D+ + A E G + + + + +
Sbjct: 2305 ELAQEQAR-----RLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAE 2359
Query: 597 VDNVENVVSFNAKEHENFLETIQEQ-QTTESAGQDLISIPKAVEPMEIDSEESESDGSFI 655
+ + +A+ E I E+ TE A Q+ +++ V+ +EI ++S+ D
Sbjct: 2360 MSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL---VQTLEIQRQQSDHDAE-- 2414
Query: 656 EVQSVISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRD-NSERDDVDGEP 714
++ I++ E + E + + EE+ ++ + E+++L + SE+D +
Sbjct: 2415 RLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL---- 2470
Query: 715 QEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATV 764
+ E+ E + + + +E+ + QQ + +Q+++R+ A++
Sbjct: 2471 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASM 2520
Score = 35.8 bits (81), Expect = 0.25
Identities = 146/781 (18%), Positives = 283/781 (36%), Gaps = 115/781 (14%)
Query: 85 KQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAF--RSKRDEALPSLTQVRREND 142
+Q V+R ++ +A ++++ E L++ A KTA RS ++E + ++ Q+R E +
Sbjct: 1521 RQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV-AVAQLREEAE 1579
Query: 143 LYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSSLPPEVKH 202
+ E E + + WQ + N+ L+ + Q + + E +
Sbjct: 1580 RRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAER 1639
Query: 203 EILTDMKEFTKRRRTLFEAMPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHSGHI 262
E RRR E + ++ +L+ K+ L + + Q+ I
Sbjct: 1640 EA---------RRRGKAEEQAVRQRELAEQELE---KQRQLAEGTAQQRLAAEQEL---I 1684
Query: 263 RRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLPSSSKMHGMSFDVK 322
R + E E G + R+++ E+ + + E+++E ++M +
Sbjct: 1685 RLRAETEQG----EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL---- 1736
Query: 323 SSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEE-----LESENRRQARGRNAPAA 377
K + E+E +T + L +A +EE L E +RQ + AA
Sbjct: 1737 ---ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAA 1793
Query: 378 VDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMRINSSTENSDEGLKVRDG 437
+ R L+ A+ + +K A ++ AE R+ E DE + R
Sbjct: 1794 RQRAE-AERVLAEKLAAIGEATRLKTEA--EIALKEKEAENERLRRLAE--DEAFQRRR- 1847
Query: 438 KGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFPISDESMIKDR 497
A+ EE +A R+ +DS + Q LV +E ++ +
Sbjct: 1848 -----LEEQAAQHKADIEERLAQL---RKASDSELERQKGLVEDTLRQRRQVEEEILALK 1899
Query: 498 KDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQNELCPYESKFD 557
E A ++ L GR + A T SK + E Q+ E +
Sbjct: 1900 AS---FEKAAAGKAELE-LELGRIRSNAEDTLR---SKEQAELEAARQRQLAAEEERR-- 1950
Query: 558 SSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHENF-LE 616
+ E + + + A+E +E + E V+ ++ V + E E
Sbjct: 1951 ----RREAEERVQKSLAAE-------EEAARQRKAALEEVERLKAKVEEARRLRERAEQE 1999
Query: 617 TIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKP 676
+ ++ Q + A Q + + + +E E + + QSV+ +AE +
Sbjct: 2000 SARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAE 2059
Query: 677 PSE----QGEEELVGTR-------------------EGEAPAESESLLRDNS-------- 705
+E Q E E +R +A A +E L ++
Sbjct: 2060 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2119
Query: 706 -------ERDDVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQE 758
++ D E ++ +K AE +L + + +EL TL L + ++ +
Sbjct: 2120 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVE-QELTTLRLQLEETDHQKNLLDEELQ 2178
Query: 759 RIAATVTGQMFLESQELLRLFGI-------PYIQAPMEAEAQCAILDLTDQTSGTITDDS 811
R+ A T SQ LF + ++A +EAE + IL D T + +++
Sbjct: 2179 RLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEA 2238
Query: 812 D 812
+
Sbjct: 2239 E 2239
Score = 32.3 bits (72), Expect = 2.8
Identities = 39/135 (28%), Positives = 65/135 (48%), Gaps = 14/135 (10%)
Query: 636 KAVEPMEIDSEESESDGSFIEV------QSVISDEELQAEFPETSKPPS-EQGEEELVGT 688
+A+E + + +EE+E EV Q + + AE SK S + +L +
Sbjct: 1504 QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERS 1563
Query: 689 REGEAPAESESLLRDNSERD-DVDGEPQEAEKDAEDSLHEWQDINLEELE-TLESNLLAQ 746
+ E A ++ LR+ +ER E + A ++AE L WQ E L L++ +AQ
Sbjct: 1564 LQEEHVAVAQ--LREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQ 1621
Query: 747 QNSL---KAQKQQQE 758
Q SL +A+KQ++E
Sbjct: 1622 QKSLAQAEAEKQKEE 1636
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 44.7 bits (104), Expect = 5e-04
Identities = 128/710 (18%), Positives = 276/710 (38%), Gaps = 84/710 (11%)
Query: 79 DAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLK---TFLKRQAIKTAFRSKRDEALPSLT 135
D+ L +++ LV+ R+ R+ E++L +F K A K + +
Sbjct: 2040 DSELERQKGLVEDTLRQ------RRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE 2093
Query: 136 QVRRENDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSS 195
R + L ++ + + EE +E +ER+ + A +EE +A E E +
Sbjct: 2094 DTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKA 2153
Query: 196 LPPEVKHEILTDMKEFTKRRRTLFEA------MPEESDDFSQYQLKGLLKKNYLNQHIEH 249
E + +E ++ + EA E++ F+ Q K+ L Q ++
Sbjct: 2154 KVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ-----KEQELQQTLQQ 2208
Query: 250 VQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLP 309
Q ++Q +R + E +E E RV +E + Q++ E ++E L
Sbjct: 2209 EQSVLDQ-----LRGEAEAARRAAEEAEEARVQAER-------EAAQSRRQVE-EAERLK 2255
Query: 310 SSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAAL-LGSSSEEELESENRRQ 368
S++ + + EKL+ E E +A R A QAAL +++ E+E +
Sbjct: 2256 QSAEEQAQARAQAQAAAEKLRKEAEQEAA----RRAQAEQAALRQKQAADAEMEKHKKFA 2311
Query: 369 ARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQ-TGGPGAEEMRINSSTEN 427
+ A V++ L+ ++ L++ + K +++Q E R S E
Sbjct: 2312 EQTLRQKAQVEQ------ELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEE 2365
Query: 428 SDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFP 487
++V+ + A + AE + + +E + V EA
Sbjct: 2366 ELFSVRVQMEELSKLKARI------EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR 2419
Query: 488 ISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQN 547
+S + R +L E + + A ++ ++ + AE+L+QQ
Sbjct: 2420 LSVAAQEAARLRQLAEEDLAQQRALA------EKMLKEKMQAVQEATRLKAEAELLQQQK 2473
Query: 548 ELCPYESKFDSSLLSSDDETKCKPNSASEVIG-----------PVSLQETSSIVSVPSEA 596
EL +++ +D+ + A E G + + + + +
Sbjct: 2474 ELAQEQAR-----RLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAE 2528
Query: 597 VDNVENVVSFNAKEHENFLETIQEQ-QTTESAGQDLISIPKAVEPMEIDSEESESDGSFI 655
+ + +A+ E I E+ TE A Q+ +++ V+ +EI ++S+ D
Sbjct: 2529 MSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL---VQTLEIQRQQSDHDAE-- 2583
Query: 656 EVQSVISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRD-NSERDDVDGEP 714
++ I++ E + E + + EE+ ++ + E+++L + SE+D +
Sbjct: 2584 RLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL---- 2639
Query: 715 QEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATV 764
+ E+ E + + + +E+ + QQ + +Q+++R+ A++
Sbjct: 2640 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASM 2689
Score = 35.8 bits (81), Expect = 0.25
Identities = 146/781 (18%), Positives = 283/781 (36%), Gaps = 115/781 (14%)
Query: 85 KQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAF--RSKRDEALPSLTQVRREND 142
+Q V+R ++ +A ++++ E L++ A KTA RS ++E + ++ Q+R E +
Sbjct: 1690 RQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV-AVAQLREEAE 1748
Query: 143 LYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSSLPPEVKH 202
+ E E + + WQ + N+ L+ + Q + + E +
Sbjct: 1749 RRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAER 1808
Query: 203 EILTDMKEFTKRRRTLFEAMPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHSGHI 262
E RRR E + ++ +L+ K+ L + + Q+ I
Sbjct: 1809 EA---------RRRGKAEEQAVRQRELAEQELE---KQRQLAEGTAQQRLAAEQEL---I 1853
Query: 263 RRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLPSSSKMHGMSFDVK 322
R + E E G + R+++ E+ + + E+++E ++M +
Sbjct: 1854 RLRAETEQG----EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL---- 1905
Query: 323 SSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEE-----LESENRRQARGRNAPAA 377
K + E+E +T + L +A +EE L E +RQ + AA
Sbjct: 1906 ---ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAA 1962
Query: 378 VDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMRINSSTENSDEGLKVRDG 437
+ R L+ A+ + +K A ++ AE R+ E DE + R
Sbjct: 1963 RQRAE-AERVLAEKLAAIGEATRLKTEA--EIALKEKEAENERLRRLAE--DEAFQRRR- 2016
Query: 438 KGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFPISDESMIKDR 497
A+ EE +A R+ +DS + Q LV +E ++ +
Sbjct: 2017 -----LEEQAAQHKADIEERLAQL---RKASDSELERQKGLVEDTLRQRRQVEEEILALK 2068
Query: 498 KDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQNELCPYESKFD 557
E A ++ L GR + A T SK + E Q+ E +
Sbjct: 2069 AS---FEKAAAGKAELE-LELGRIRSNAEDTLR---SKEQAELEAARQRQLAAEEERR-- 2119
Query: 558 SSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHENF-LE 616
+ E + + + A+E +E + E V+ ++ V + E E
Sbjct: 2120 ----RREAEERVQKSLAAE-------EEAARQRKAALEEVERLKAKVEEARRLRERAEQE 2168
Query: 617 TIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKP 676
+ ++ Q + A Q + + + +E E + + QSV+ +AE +
Sbjct: 2169 SARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAE 2228
Query: 677 PSE----QGEEELVGTR-------------------EGEAPAESESLLRDNS-------- 705
+E Q E E +R +A A +E L ++
Sbjct: 2229 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2288
Query: 706 -------ERDDVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQE 758
++ D E ++ +K AE +L + + +EL TL L + ++ +
Sbjct: 2289 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVE-QELTTLRLQLEETDHQKNLLDEELQ 2347
Query: 759 RIAATVTGQMFLESQELLRLFGI-------PYIQAPMEAEAQCAILDLTDQTSGTITDDS 811
R+ A T SQ LF + ++A +EAE + IL D T + +++
Sbjct: 2348 RLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEA 2407
Query: 812 D 812
+
Sbjct: 2408 E 2408
Score = 32.3 bits (72), Expect = 2.8
Identities = 39/135 (28%), Positives = 65/135 (48%), Gaps = 14/135 (10%)
Query: 636 KAVEPMEIDSEESESDGSFIEV------QSVISDEELQAEFPETSKPPS-EQGEEELVGT 688
+A+E + + +EE+E EV Q + + AE SK S + +L +
Sbjct: 1673 QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERS 1732
Query: 689 REGEAPAESESLLRDNSERD-DVDGEPQEAEKDAEDSLHEWQDINLEELE-TLESNLLAQ 746
+ E A ++ LR+ +ER E + A ++AE L WQ E L L++ +AQ
Sbjct: 1733 LQEEHVAVAQ--LREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQ 1790
Query: 747 QNSL---KAQKQQQE 758
Q SL +A+KQ++E
Sbjct: 1791 QKSLAQAEAEKQKEE 1805
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 44.7 bits (104), Expect = 5e-04
Identities = 128/710 (18%), Positives = 276/710 (38%), Gaps = 84/710 (11%)
Query: 79 DAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLK---TFLKRQAIKTAFRSKRDEALPSLT 135
D+ L +++ LV+ R+ R+ E++L +F K A K + +
Sbjct: 1881 DSELERQKGLVEDTLRQ------RRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE 1934
Query: 136 QVRRENDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSS 195
R + L ++ + + EE +E +ER+ + A +EE +A E E +
Sbjct: 1935 DTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKA 1994
Query: 196 LPPEVKHEILTDMKEFTKRRRTLFEA------MPEESDDFSQYQLKGLLKKNYLNQHIEH 249
E + +E ++ + EA E++ F+ Q K+ L Q ++
Sbjct: 1995 KVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ-----KEQELQQTLQQ 2049
Query: 250 VQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLP 309
Q ++Q +R + E +E E RV +E + Q++ E ++E L
Sbjct: 2050 EQSVLDQ-----LRGEAEAARRAAEEAEEARVQAER-------EAAQSRRQVE-EAERLK 2096
Query: 310 SSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAAL-LGSSSEEELESENRRQ 368
S++ + + EKL+ E E +A R A QAAL +++ E+E +
Sbjct: 2097 QSAEEQAQARAQAQAAAEKLRKEAEQEAA----RRAQAEQAALRQKQAADAEMEKHKKFA 2152
Query: 369 ARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQ-TGGPGAEEMRINSSTEN 427
+ A V++ L+ ++ L++ + K +++Q E R S E
Sbjct: 2153 EQTLRQKAQVEQ------ELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEE 2206
Query: 428 SDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFP 487
++V+ + A + AE + + +E + V EA
Sbjct: 2207 ELFSVRVQMEELSKLKARI------EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR 2260
Query: 488 ISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQN 547
+S + R +L E + + A ++ ++ + AE+L+QQ
Sbjct: 2261 LSVAAQEAARLRQLAEEDLAQQRALA------EKMLKEKMQAVQEATRLKAEAELLQQQK 2314
Query: 548 ELCPYESKFDSSLLSSDDETKCKPNSASEVIG-----------PVSLQETSSIVSVPSEA 596
EL +++ +D+ + A E G + + + + +
Sbjct: 2315 ELAQEQAR-----RLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAE 2369
Query: 597 VDNVENVVSFNAKEHENFLETIQEQ-QTTESAGQDLISIPKAVEPMEIDSEESESDGSFI 655
+ + +A+ E I E+ TE A Q+ +++ V+ +EI ++S+ D
Sbjct: 2370 MSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL---VQTLEIQRQQSDHDAE-- 2424
Query: 656 EVQSVISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRD-NSERDDVDGEP 714
++ I++ E + E + + EE+ ++ + E+++L + SE+D +
Sbjct: 2425 RLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL---- 2480
Query: 715 QEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATV 764
+ E+ E + + + +E+ + QQ + +Q+++R+ A++
Sbjct: 2481 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASM 2530
Score = 35.8 bits (81), Expect = 0.25
Identities = 146/781 (18%), Positives = 283/781 (36%), Gaps = 115/781 (14%)
Query: 85 KQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAF--RSKRDEALPSLTQVRREND 142
+Q V+R ++ +A ++++ E L++ A KTA RS ++E + ++ Q+R E +
Sbjct: 1531 RQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV-AVAQLREEAE 1589
Query: 143 LYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSSLPPEVKH 202
+ E E + + WQ + N+ L+ + Q + + E +
Sbjct: 1590 RRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAER 1649
Query: 203 EILTDMKEFTKRRRTLFEAMPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHSGHI 262
E RRR E + ++ +L+ K+ L + + Q+ I
Sbjct: 1650 EA---------RRRGKAEEQAVRQRELAEQELE---KQRQLAEGTAQQRLAAEQEL---I 1694
Query: 263 RRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLPSSSKMHGMSFDVK 322
R + E E G + R+++ E+ + + E+++E ++M +
Sbjct: 1695 RLRAETEQG----EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL---- 1746
Query: 323 SSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEE-----LESENRRQARGRNAPAA 377
K + E+E +T + L +A +EE L E +RQ + AA
Sbjct: 1747 ---ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAA 1803
Query: 378 VDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMRINSSTENSDEGLKVRDG 437
+ R L+ A+ + +K A ++ AE R+ E DE + R
Sbjct: 1804 RQRAE-AERVLAEKLAAIGEATRLKTEA--EIALKEKEAENERLRRLAE--DEAFQRRR- 1857
Query: 438 KGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFPISDESMIKDR 497
A+ EE +A R+ +DS + Q LV +E ++ +
Sbjct: 1858 -----LEEQAAQHKADIEERLAQL---RKASDSELERQKGLVEDTLRQRRQVEEEILALK 1909
Query: 498 KDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQNELCPYESKFD 557
E A ++ L GR + A T SK + E Q+ E +
Sbjct: 1910 AS---FEKAAAGKAELE-LELGRIRSNAEDTLR---SKEQAELEAARQRQLAAEEERR-- 1960
Query: 558 SSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHENF-LE 616
+ E + + + A+E +E + E V+ ++ V + E E
Sbjct: 1961 ----RREAEERVQKSLAAE-------EEAARQRKAALEEVERLKAKVEEARRLRERAEQE 2009
Query: 617 TIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKP 676
+ ++ Q + A Q + + + +E E + + QSV+ +AE +
Sbjct: 2010 SARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAE 2069
Query: 677 PSE----QGEEELVGTR-------------------EGEAPAESESLLRDNS-------- 705
+E Q E E +R +A A +E L ++
Sbjct: 2070 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2129
Query: 706 -------ERDDVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQE 758
++ D E ++ +K AE +L + + +EL TL L + ++ +
Sbjct: 2130 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVE-QELTTLRLQLEETDHQKNLLDEELQ 2188
Query: 759 RIAATVTGQMFLESQELLRLFGI-------PYIQAPMEAEAQCAILDLTDQTSGTITDDS 811
R+ A T SQ LF + ++A +EAE + IL D T + +++
Sbjct: 2189 RLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEA 2248
Query: 812 D 812
+
Sbjct: 2249 E 2249
Score = 32.3 bits (72), Expect = 2.8
Identities = 39/135 (28%), Positives = 65/135 (48%), Gaps = 14/135 (10%)
Query: 636 KAVEPMEIDSEESESDGSFIEV------QSVISDEELQAEFPETSKPPS-EQGEEELVGT 688
+A+E + + +EE+E EV Q + + AE SK S + +L +
Sbjct: 1514 QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERS 1573
Query: 689 REGEAPAESESLLRDNSERD-DVDGEPQEAEKDAEDSLHEWQDINLEELE-TLESNLLAQ 746
+ E A ++ LR+ +ER E + A ++AE L WQ E L L++ +AQ
Sbjct: 1574 LQEEHVAVAQ--LREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQ 1631
Query: 747 QNSL---KAQKQQQE 758
Q SL +A+KQ++E
Sbjct: 1632 QKSLAQAEAEKQKEE 1646
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 44.7 bits (104), Expect = 5e-04
Identities = 128/710 (18%), Positives = 276/710 (38%), Gaps = 84/710 (11%)
Query: 79 DAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLK---TFLKRQAIKTAFRSKRDEALPSLT 135
D+ L +++ LV+ R+ R+ E++L +F K A K + +
Sbjct: 1889 DSELERQKGLVEDTLRQ------RRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE 1942
Query: 136 QVRRENDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSS 195
R + L ++ + + EE +E +ER+ + A +EE +A E E +
Sbjct: 1943 DTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKA 2002
Query: 196 LPPEVKHEILTDMKEFTKRRRTLFEA------MPEESDDFSQYQLKGLLKKNYLNQHIEH 249
E + +E ++ + EA E++ F+ Q K+ L Q ++
Sbjct: 2003 KVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ-----KEQELQQTLQQ 2057
Query: 250 VQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLP 309
Q ++Q +R + E +E E RV +E + Q++ E ++E L
Sbjct: 2058 EQSVLDQ-----LRGEAEAARRAAEEAEEARVQAER-------EAAQSRRQVE-EAERLK 2104
Query: 310 SSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAAL-LGSSSEEELESENRRQ 368
S++ + + EKL+ E E +A R A QAAL +++ E+E +
Sbjct: 2105 QSAEEQAQARAQAQAAAEKLRKEAEQEAA----RRAQAEQAALRQKQAADAEMEKHKKFA 2160
Query: 369 ARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQ-TGGPGAEEMRINSSTEN 427
+ A V++ L+ ++ L++ + K +++Q E R S E
Sbjct: 2161 EQTLRQKAQVEQ------ELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEE 2214
Query: 428 SDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFP 487
++V+ + A + AE + + +E + V EA
Sbjct: 2215 ELFSVRVQMEELSKLKARI------EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR 2268
Query: 488 ISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQN 547
+S + R +L E + + A ++ ++ + AE+L+QQ
Sbjct: 2269 LSVAAQEAARLRQLAEEDLAQQRALA------EKMLKEKMQAVQEATRLKAEAELLQQQK 2322
Query: 548 ELCPYESKFDSSLLSSDDETKCKPNSASEVIG-----------PVSLQETSSIVSVPSEA 596
EL +++ +D+ + A E G + + + + +
Sbjct: 2323 ELAQEQAR-----RLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAE 2377
Query: 597 VDNVENVVSFNAKEHENFLETIQEQ-QTTESAGQDLISIPKAVEPMEIDSEESESDGSFI 655
+ + +A+ E I E+ TE A Q+ +++ V+ +EI ++S+ D
Sbjct: 2378 MSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL---VQTLEIQRQQSDHDAE-- 2432
Query: 656 EVQSVISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRD-NSERDDVDGEP 714
++ I++ E + E + + EE+ ++ + E+++L + SE+D +
Sbjct: 2433 RLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL---- 2488
Query: 715 QEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATV 764
+ E+ E + + + +E+ + QQ + +Q+++R+ A++
Sbjct: 2489 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASM 2538
Score = 35.8 bits (81), Expect = 0.25
Identities = 146/781 (18%), Positives = 283/781 (36%), Gaps = 115/781 (14%)
Query: 85 KQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAF--RSKRDEALPSLTQVRREND 142
+Q V+R ++ +A ++++ E L++ A KTA RS ++E + ++ Q+R E +
Sbjct: 1539 RQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV-AVAQLREEAE 1597
Query: 143 LYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSSLPPEVKH 202
+ E E + + WQ + N+ L+ + Q + + E +
Sbjct: 1598 RRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAER 1657
Query: 203 EILTDMKEFTKRRRTLFEAMPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHSGHI 262
E RRR E + ++ +L+ K+ L + + Q+ I
Sbjct: 1658 EA---------RRRGKAEEQAVRQRELAEQELE---KQRQLAEGTAQQRLAAEQEL---I 1702
Query: 263 RRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLPSSSKMHGMSFDVK 322
R + E E G + R+++ E+ + + E+++E ++M +
Sbjct: 1703 RLRAETEQG----EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL---- 1754
Query: 323 SSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEE-----LESENRRQARGRNAPAA 377
K + E+E +T + L +A +EE L E +RQ + AA
Sbjct: 1755 ---ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAA 1811
Query: 378 VDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMRINSSTENSDEGLKVRDG 437
+ R L+ A+ + +K A ++ AE R+ E DE + R
Sbjct: 1812 RQRAE-AERVLAEKLAAIGEATRLKTEA--EIALKEKEAENERLRRLAE--DEAFQRRR- 1865
Query: 438 KGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFPISDESMIKDR 497
A+ EE +A R+ +DS + Q LV +E ++ +
Sbjct: 1866 -----LEEQAAQHKADIEERLAQL---RKASDSELERQKGLVEDTLRQRRQVEEEILALK 1917
Query: 498 KDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQNELCPYESKFD 557
E A ++ L GR + A T SK + E Q+ E +
Sbjct: 1918 AS---FEKAAAGKAELE-LELGRIRSNAEDTLR---SKEQAELEAARQRQLAAEEERR-- 1968
Query: 558 SSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHENF-LE 616
+ E + + + A+E +E + E V+ ++ V + E E
Sbjct: 1969 ----RREAEERVQKSLAAE-------EEAARQRKAALEEVERLKAKVEEARRLRERAEQE 2017
Query: 617 TIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKP 676
+ ++ Q + A Q + + + +E E + + QSV+ +AE +
Sbjct: 2018 SARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAE 2077
Query: 677 PSE----QGEEELVGTR-------------------EGEAPAESESLLRDNS-------- 705
+E Q E E +R +A A +E L ++
Sbjct: 2078 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2137
Query: 706 -------ERDDVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQE 758
++ D E ++ +K AE +L + + +EL TL L + ++ +
Sbjct: 2138 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVE-QELTTLRLQLEETDHQKNLLDEELQ 2196
Query: 759 RIAATVTGQMFLESQELLRLFGI-------PYIQAPMEAEAQCAILDLTDQTSGTITDDS 811
R+ A T SQ LF + ++A +EAE + IL D T + +++
Sbjct: 2197 RLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEA 2256
Query: 812 D 812
+
Sbjct: 2257 E 2257
Score = 32.3 bits (72), Expect = 2.8
Identities = 39/135 (28%), Positives = 65/135 (48%), Gaps = 14/135 (10%)
Query: 636 KAVEPMEIDSEESESDGSFIEV------QSVISDEELQAEFPETSKPPS-EQGEEELVGT 688
+A+E + + +EE+E EV Q + + AE SK S + +L +
Sbjct: 1522 QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERS 1581
Query: 689 REGEAPAESESLLRDNSERD-DVDGEPQEAEKDAEDSLHEWQDINLEELE-TLESNLLAQ 746
+ E A ++ LR+ +ER E + A ++AE L WQ E L L++ +AQ
Sbjct: 1582 LQEEHVAVAQ--LREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQ 1639
Query: 747 QNSL---KAQKQQQE 758
Q SL +A+KQ++E
Sbjct: 1640 QKSLAQAEAEKQKEE 1654
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 44.7 bits (104), Expect = 5e-04
Identities = 128/710 (18%), Positives = 276/710 (38%), Gaps = 84/710 (11%)
Query: 79 DAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLK---TFLKRQAIKTAFRSKRDEALPSLT 135
D+ L +++ LV+ R+ R+ E++L +F K A K + +
Sbjct: 1930 DSELERQKGLVEDTLRQ------RRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE 1983
Query: 136 QVRRENDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSS 195
R + L ++ + + EE +E +ER+ + A +EE +A E E +
Sbjct: 1984 DTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKA 2043
Query: 196 LPPEVKHEILTDMKEFTKRRRTLFEA------MPEESDDFSQYQLKGLLKKNYLNQHIEH 249
E + +E ++ + EA E++ F+ Q K+ L Q ++
Sbjct: 2044 KVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ-----KEQELQQTLQQ 2098
Query: 250 VQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLP 309
Q ++Q +R + E +E E RV +E + Q++ E ++E L
Sbjct: 2099 EQSVLDQ-----LRGEAEAARRAAEEAEEARVQAER-------EAAQSRRQVE-EAERLK 2145
Query: 310 SSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAAL-LGSSSEEELESENRRQ 368
S++ + + EKL+ E E +A R A QAAL +++ E+E +
Sbjct: 2146 QSAEEQAQARAQAQAAAEKLRKEAEQEAA----RRAQAEQAALRQKQAADAEMEKHKKFA 2201
Query: 369 ARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQ-TGGPGAEEMRINSSTEN 427
+ A V++ L+ ++ L++ + K +++Q E R S E
Sbjct: 2202 EQTLRQKAQVEQ------ELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEE 2255
Query: 428 SDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFP 487
++V+ + A + AE + + +E + V EA
Sbjct: 2256 ELFSVRVQMEELSKLKARI------EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR 2309
Query: 488 ISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQN 547
+S + R +L E + + A ++ ++ + AE+L+QQ
Sbjct: 2310 LSVAAQEAARLRQLAEEDLAQQRALA------EKMLKEKMQAVQEATRLKAEAELLQQQK 2363
Query: 548 ELCPYESKFDSSLLSSDDETKCKPNSASEVIG-----------PVSLQETSSIVSVPSEA 596
EL +++ +D+ + A E G + + + + +
Sbjct: 2364 ELAQEQAR-----RLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAE 2418
Query: 597 VDNVENVVSFNAKEHENFLETIQEQ-QTTESAGQDLISIPKAVEPMEIDSEESESDGSFI 655
+ + +A+ E I E+ TE A Q+ +++ V+ +EI ++S+ D
Sbjct: 2419 MSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL---VQTLEIQRQQSDHDAE-- 2473
Query: 656 EVQSVISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRD-NSERDDVDGEP 714
++ I++ E + E + + EE+ ++ + E+++L + SE+D +
Sbjct: 2474 RLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL---- 2529
Query: 715 QEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATV 764
+ E+ E + + + +E+ + QQ + +Q+++R+ A++
Sbjct: 2530 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASM 2579
Score = 35.8 bits (81), Expect = 0.25
Identities = 146/781 (18%), Positives = 283/781 (36%), Gaps = 115/781 (14%)
Query: 85 KQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAF--RSKRDEALPSLTQVRREND 142
+Q V+R ++ +A ++++ E L++ A KTA RS ++E + ++ Q+R E +
Sbjct: 1580 RQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV-AVAQLREEAE 1638
Query: 143 LYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSSLPPEVKH 202
+ E E + + WQ + N+ L+ + Q + + E +
Sbjct: 1639 RRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAER 1698
Query: 203 EILTDMKEFTKRRRTLFEAMPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHSGHI 262
E RRR E + ++ +L+ K+ L + + Q+ I
Sbjct: 1699 EA---------RRRGKAEEQAVRQRELAEQELE---KQRQLAEGTAQQRLAAEQEL---I 1743
Query: 263 RRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLPSSSKMHGMSFDVK 322
R + E E G + R+++ E+ + + E+++E ++M +
Sbjct: 1744 RLRAETEQG----EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL---- 1795
Query: 323 SSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEE-----LESENRRQARGRNAPAA 377
K + E+E +T + L +A +EE L E +RQ + AA
Sbjct: 1796 ---ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAA 1852
Query: 378 VDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMRINSSTENSDEGLKVRDG 437
+ R L+ A+ + +K A ++ AE R+ E DE + R
Sbjct: 1853 RQRAE-AERVLAEKLAAIGEATRLKTEA--EIALKEKEAENERLRRLAE--DEAFQRRR- 1906
Query: 438 KGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFPISDESMIKDR 497
A+ EE +A R+ +DS + Q LV +E ++ +
Sbjct: 1907 -----LEEQAAQHKADIEERLAQL---RKASDSELERQKGLVEDTLRQRRQVEEEILALK 1958
Query: 498 KDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQNELCPYESKFD 557
E A ++ L GR + A T SK + E Q+ E +
Sbjct: 1959 AS---FEKAAAGKAELE-LELGRIRSNAEDTLR---SKEQAELEAARQRQLAAEEERR-- 2009
Query: 558 SSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHENF-LE 616
+ E + + + A+E +E + E V+ ++ V + E E
Sbjct: 2010 ----RREAEERVQKSLAAE-------EEAARQRKAALEEVERLKAKVEEARRLRERAEQE 2058
Query: 617 TIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKP 676
+ ++ Q + A Q + + + +E E + + QSV+ +AE +
Sbjct: 2059 SARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAE 2118
Query: 677 PSE----QGEEELVGTR-------------------EGEAPAESESLLRDNS-------- 705
+E Q E E +R +A A +E L ++
Sbjct: 2119 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2178
Query: 706 -------ERDDVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQE 758
++ D E ++ +K AE +L + + +EL TL L + ++ +
Sbjct: 2179 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVE-QELTTLRLQLEETDHQKNLLDEELQ 2237
Query: 759 RIAATVTGQMFLESQELLRLFGI-------PYIQAPMEAEAQCAILDLTDQTSGTITDDS 811
R+ A T SQ LF + ++A +EAE + IL D T + +++
Sbjct: 2238 RLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEA 2297
Query: 812 D 812
+
Sbjct: 2298 E 2298
Score = 32.3 bits (72), Expect = 2.8
Identities = 39/135 (28%), Positives = 65/135 (48%), Gaps = 14/135 (10%)
Query: 636 KAVEPMEIDSEESESDGSFIEV------QSVISDEELQAEFPETSKPPS-EQGEEELVGT 688
+A+E + + +EE+E EV Q + + AE SK S + +L +
Sbjct: 1563 QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERS 1622
Query: 689 REGEAPAESESLLRDNSERD-DVDGEPQEAEKDAEDSLHEWQDINLEELE-TLESNLLAQ 746
+ E A ++ LR+ +ER E + A ++AE L WQ E L L++ +AQ
Sbjct: 1623 LQEEHVAVAQ--LREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQ 1680
Query: 747 QNSL---KAQKQQQE 758
Q SL +A+KQ++E
Sbjct: 1681 QKSLAQAEAEKQKEE 1695
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 43.9 bits (102), Expect = 0.001
Identities = 73/426 (17%), Positives = 149/426 (34%), Gaps = 22/426 (5%)
Query: 304 DSESLPSSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEELES 363
DS+S S+S S D SS + +++ S S S + +S
Sbjct: 568 DSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSD-----------SSDSSDSSDS 616
Query: 364 ENRRQARGRNAPAAVDEGSISPRTLSAIKRALD-----DDEDVKVCAGDDVQTGGPGAEE 418
+ ++ ++ + D ++ S+ + D D D + + + +
Sbjct: 617 SDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD 676
Query: 419 MRINSSTENSDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSL 478
+S + NS + D ++ + SS + + + S+N +DS S
Sbjct: 677 SSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD 736
Query: 479 VHVGTEAFPISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNET 538
+++ SD S D D S SD+ + + + +S + ++ S N +
Sbjct: 737 SSNSSDSSDSSDSSNSSDSSD----SSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSS 792
Query: 539 HAEVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVD 598
+ ++ DSS S D + +S S S SS S S+ D
Sbjct: 793 DSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSD 852
Query: 599 NVENVVSFNAKEHENFLETIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQ 658
+ + S ++ ++ + + S D + + + S S+SD S
Sbjct: 853 SDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSD-SSNSSDSDSSDSSNS 911
Query: 659 SVISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAE 718
S SD ++ E+S + + + ++S S D+S D ++
Sbjct: 912 SDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDS-SNSSDSSNSSDSSNSSDSSD 970
Query: 719 KDAEDS 724
++ DS
Sbjct: 971 SNSSDS 976
Score = 40.8 bits (94), Expect = 0.008
Identities = 74/423 (17%), Positives = 144/423 (34%), Gaps = 31/423 (7%)
Query: 305 SESLPSSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEELESE 364
S+S SSS + S + + + D++ S SS + +
Sbjct: 672 SDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSD----------SSDSSDSSNS 721
Query: 365 NRRQARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMRINSS 424
N + N+ + D + S + S+ D D + + + + +S+
Sbjct: 722 NSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 781
Query: 425 TENSDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTE 484
+ +S++ D +S+S +S+ +S + +DS S ++
Sbjct: 782 SSDSNDSSNSSDSSD-------SSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSD 834
Query: 485 AFPISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLE 544
+ SD S D D +S+ N + + +S + +S S N + +
Sbjct: 835 SSNSSDSSDSSDSSDGSDSDSS-----------NRSDSSNSSDSSDSSDSSNSSDSSDSS 883
Query: 545 QQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVV 604
NE DSS S D + +S S S SS S S + D+ +
Sbjct: 884 DSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSD 943
Query: 605 SFNAKEHENFLETIQEQQTTESA-GQDLISIPKAVEPMEIDSEES--ESDGSFIEVQSVI 661
S ++ + N ++ ++ S+ D S + DS +S SD S S
Sbjct: 944 SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS 1003
Query: 662 SDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKDA 721
SD ++ ++S + + + ++S + D D D+
Sbjct: 1004 SDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1063
Query: 722 EDS 724
DS
Sbjct: 1064 SDS 1066
Score = 40.8 bits (94), Expect = 0.008
Identities = 26/97 (26%), Positives = 42/97 (43%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+N+ + S S SDS + + S+SSD S S D+ SS + ++
Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDS 1237
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDGGK 1157
+ +SDS NS + + +TS S+D D K
Sbjct: 1238 SDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSK 1274
Score = 40.4 bits (93), Expect = 0.010
Identities = 72/366 (19%), Positives = 133/366 (36%), Gaps = 51/366 (13%)
Query: 362 ESENRRQARGR---NAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEE 418
ES+N +RG N+ + D G+ S K A DDD D T +
Sbjct: 480 ESDNNSSSRGDASYNSDESKDNGNGSDS-----KGAEDDDSD---------STSDTNNSD 525
Query: 419 MRINSSTENSDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSL 478
N + N D K GKG S S +S +++++ + +DS +
Sbjct: 526 SNGNGNNGNDDND-KSDSGKG-------KSDSSDSDSSDSSNSSDSSDSSDSDSSD---- 573
Query: 479 VHVGTEAFPISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNET 538
S+ S D D +S+ SD+ + + + +S + +S S +++
Sbjct: 574 ----------SNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDS-SDS 622
Query: 539 HAEVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVD 598
++ + +++ +SK DSS +S D + +S S S SS S S + D
Sbjct: 623 KSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSD 682
Query: 599 NVENVVSFNAKEHENFLETIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQ 658
+ + S ++ + N E+ +++S D DS S S S
Sbjct: 683 SSNSSDSSDSSDSSNSSESSDSSDSSDSDSSD-----------SSDSSNSNSSDSDSSNS 731
Query: 659 SVISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAE 718
S SD ++ ++S + + + ++S + + D
Sbjct: 732 SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNS 791
Query: 719 KDAEDS 724
D+ DS
Sbjct: 792 SDSSDS 797
Score = 38.5 bits (88), Expect = 0.038
Identities = 23/92 (25%), Positives = 43/92 (46%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ + S S SDS + + SESSD S S D++SS + ++
Sbjct: 666 SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSD 725
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSD 1152
+++SDS +S + + +++SS SD
Sbjct: 726 SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSD 757
Score = 37.7 bits (86), Expect = 0.066
Identities = 72/435 (16%), Positives = 144/435 (33%), Gaps = 16/435 (3%)
Query: 304 DSESLPSSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEELES 363
DS + SS S +SS D++ S ++ SS+ S
Sbjct: 682 DSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSS 741
Query: 364 ENRRQARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMRINS 423
++ + N+ + D S + S+ D D + + + + + +S
Sbjct: 742 DSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSS 801
Query: 424 STENSDEGLKVRDGKGIPFTATLASS-------SVNSAEEHVASTNEGREPTDSVPKEQM 476
+ NS + D + + SS S NS++ +S + +DS +
Sbjct: 802 DSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDS 861
Query: 477 SLVHVGTEAFPISDESMIKDRKDRLPL-------ESAVVRHSDAPGLPNGRELTPASPTC 529
S +++ S+ S D D +S+ SD+ N + + +S +
Sbjct: 862 SNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSS 921
Query: 530 TNSVSKNETHAEVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVSLQETSSI 589
+S S N + + DSS S + NS+ S SS
Sbjct: 922 DSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSN 981
Query: 590 VSVPSEAVDNVENVVSFNAKEHENFLETIQEQQTTESAGQDLISIPKAVEPMEIDSEESE 649
S S++ D+ ++ S ++ + ++ ++ S+ S S+ S+
Sbjct: 982 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSD 1041
Query: 650 SDGSFIEVQSVISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRDNSERDD 709
S S S SD ++ ++S + + + ++S + D
Sbjct: 1042 SSDSSDSSDS--SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDS 1099
Query: 710 VDGEPQEAEKDAEDS 724
D D+ DS
Sbjct: 1100 SDSSDSSDSSDSSDS 1114
Score = 37.4 bits (85), Expect = 0.086
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 11/93 (11%)
Query: 1066 ESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTS 1125
ES S SDS N+ S+SSD S S D+ +SS + ++ +S
Sbjct: 630 ESDSSDSDSKSDSSDSNS----------SDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSS 679
Query: 1126 ASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKE 1158
+SDS NS ++ + + +S SSDS D +
Sbjct: 680 SSDSSNS-SDSSDSSDSSNSSESSDSSDSSDSD 711
Score = 37.0 bits (84), Expect = 0.11
Identities = 22/93 (23%), Positives = 43/93 (46%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+N+ + + S SDS + + S+SSD SS ++SS+ + + +
Sbjct: 780 SNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS 839
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+ S+ S S ++ ++ + +S SSDS D
Sbjct: 840 DSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSD 872
Score = 36.6 bits (83), Expect = 0.15
Identities = 26/106 (24%), Positives = 43/106 (40%), Gaps = 3/106 (2%)
Query: 1049 DKAKRKTQKRGITNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESS 1108
D + + +N+ + S S SDS + + S SSD S S D+ S
Sbjct: 717 DSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDS 776
Query: 1109 SLMNVQRRTAAKEPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDD 1154
S ++ +++SDS +S + N ++ SS SD D
Sbjct: 777 S---DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSD 819
Score = 36.6 bits (83), Expect = 0.15
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 10/98 (10%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+N+ + S S SDS + + S+SSD S S D+ +SS N ++
Sbjct: 738 SNSSDSSDSSDSSNSSDSSDSSDSSN---SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDS 794
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKE 1158
+++SDS NS + + +S SSDSD +
Sbjct: 795 SDSSNSSDSSNS-------SDSSDSSDSSDSDSSNSSD 825
Score = 36.6 bits (83), Expect = 0.15
Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 1/93 (1%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ + S+S SDS + + S+SSD S S D+ +SS + ++
Sbjct: 1010 SDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1069
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+ +SDS +S E+ + + +S SSDS D
Sbjct: 1070 SDSSDSSDSSDS-SESSDSSDSSNSSDSSDSSD 1101
Score = 36.2 bits (82), Expect = 0.19
Identities = 22/83 (26%), Positives = 36/83 (43%)
Query: 1076 SDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTSASDSQNSVKE 1135
SDS + + S+SSD S+S D+ SS + ++ + +SDS NS
Sbjct: 726 SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 785
Query: 1136 APVKNGGATTSSSSDSDDDGGKE 1158
N ++ SS+ SD +
Sbjct: 786 NDSSNSSDSSDSSNSSDSSNSSD 808
Score = 36.2 bits (82), Expect = 0.19
Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+N+ + S+S SDS + + S SSD S S D+ SS + ++
Sbjct: 1022 SNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1081
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+ +SDS NS ++ + + +S SSDS D
Sbjct: 1082 SESSDSSDSSNS-SDSSDSSDSSDSSDSSDSSD 1113
Score = 36.2 bits (82), Expect = 0.19
Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 1/93 (1%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+N+ + S S SDS + + S+SSD S S D+ SS + ++
Sbjct: 1028 SNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDS 1087
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+++SDS +S ++ + + +S SSDS D
Sbjct: 1088 SDSSNSSDSSDS-SDSSDSSDSSDSSDSSDSSD 1119
Score = 35.8 bits (81), Expect = 0.25
Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 1/93 (1%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+N+ + S S SDS + + S+SSD S S D+ +SS + ++
Sbjct: 971 SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNS 1030
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+ +SDS +S ++ + + +S+SSDS D
Sbjct: 1031 SDSSDSSDSSDS-SDSSDSSDSSDSSNSSDSSD 1062
Score = 35.8 bits (81), Expect = 0.25
Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 1/93 (1%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+N+ + S S + SDS + + S+SSD S+S D+ SS + ++
Sbjct: 1139 SNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1198
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+ +SDS +S ++ + + +S SSDS D
Sbjct: 1199 SDSSDSSDSSDS-SDSSDSSDSSDSSDSSDSSD 1230
Score = 35.4 bits (80), Expect = 0.33
Identities = 23/79 (29%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
Query: 1076 SDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTSASDSQNSV-K 1134
+D K+ G ++ S+SSD S+S D+ SS + ++ + +S SDS +S
Sbjct: 534 NDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDS 593
Query: 1135 EAPVKNGGATTSSSSDSDD 1153
++ + + +S SSDS D
Sbjct: 594 DSSDSSNSSDSSDSSDSSD 612
Score = 35.4 bits (80), Expect = 0.33
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 4/93 (4%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ + SSS SDS + + S+SSD S S+ ++SS N +
Sbjct: 672 SDSSDSSSSSDSSNSSDSSDSSDSSN---SSESSDSSDSSDSDSSDSSDSSNSNSSDSDS 728
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+ +SDS NS ++ + + +S SSDS D
Sbjct: 729 SNSSDSSDSSNS-SDSSDSSDSSNSSDSSDSSD 760
Score = 35.4 bits (80), Expect = 0.33
Identities = 24/94 (25%), Positives = 45/94 (47%), Gaps = 1/94 (1%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+N+ + S S SDS + + S+S+D S+S D+ SS + ++
Sbjct: 750 SNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDS 809
Query: 1121 EPKTSASDSQNS-VKEAPVKNGGATTSSSSDSDD 1153
+ +SDS +S ++ + + +S+SSDS D
Sbjct: 810 SDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSD 843
Score = 35.4 bits (80), Expect = 0.33
Identities = 18/65 (27%), Positives = 33/65 (50%)
Query: 1094 SESSDGSSSEDAESSSLMNVQRRTAAKEPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
S+SSD S+S D+ SS + ++ +++SDS NS + + ++ SS+ SD
Sbjct: 903 SDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDS 962
Query: 1154 DGGKE 1158
+
Sbjct: 963 SNSSD 967
Score = 35.4 bits (80), Expect = 0.33
Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ + S S SDS + + S+SSD S S D+ SS + ++
Sbjct: 1070 SDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1129
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+ +SDS NS ++ + + +S SSDS D
Sbjct: 1130 SDSSDSSDSSNS-SDSSDSSESSDSSDSSDSSD 1161
Score = 35.4 bits (80), Expect = 0.33
Identities = 23/98 (23%), Positives = 42/98 (42%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+N+ + S S SDS + + S+SSD S S D+ SS + ++
Sbjct: 1091 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSES 1150
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKE 1158
+ +SDS +S + + ++ SS+ SD +
Sbjct: 1151 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1188
Score = 35.4 bits (80), Expect = 0.33
Identities = 23/98 (23%), Positives = 42/98 (42%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ + S S SDS + + S+SSD S+S D+ SS + ++
Sbjct: 1100 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDS 1159
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKE 1158
+ +SDS +S + N ++ SS SD +
Sbjct: 1160 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD 1197
Score = 35.4 bits (80), Expect = 0.33
Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ + S S SDS + + S+SSD S S D+ SS + ++
Sbjct: 1109 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDS 1168
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+ +SDS NS ++ + + +S SSDS D
Sbjct: 1169 SDSSDSSDSSNS-SDSSDSSDSSDSSDSSDSSD 1200
Score = 35.0 bits (79), Expect = 0.42
Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 2/91 (2%)
Query: 1066 ESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTS 1125
+SS SDS + + S+SSD S D++SS+ + + + + S
Sbjct: 814 DSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS 873
Query: 1126 --ASDSQNSVKEAPVKNGGATTSSSSDSDDD 1154
+SDS +S N ++ SS+ SD D
Sbjct: 874 SNSSDSSDSSDSNESSNSSDSSDSSNSSDSD 904
Score = 35.0 bits (79), Expect = 0.42
Identities = 23/92 (25%), Positives = 40/92 (43%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ + S S SDS + + S+SSD S S D+ SS + ++
Sbjct: 1043 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDS 1102
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSD 1152
+ +SDS +S + N ++ SS SD
Sbjct: 1103 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1134
Score = 35.0 bits (79), Expect = 0.42
Identities = 24/98 (24%), Positives = 42/98 (42%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ S S SDS + + S+SSD S+S D+ SS + ++
Sbjct: 1052 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDS 1111
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKE 1158
+ +SDS NS + + ++ SS+ SD E
Sbjct: 1112 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSE 1149
Score = 35.0 bits (79), Expect = 0.42
Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 1/93 (1%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ + S+S SDS + + SESSD S S D+ SS + ++
Sbjct: 1115 SDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDS 1174
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+++SDS +S ++ + + +S SSDS D
Sbjct: 1175 SDSSNSSDSSDS-SDSSDSSDSSDSSDSSDSSD 1206
Score = 35.0 bits (79), Expect = 0.42
Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+N+ + S S SDS + + S+SSD S S D+ SS + ++
Sbjct: 1121 SNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1180
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+ +SDS +S ++ + + +S SSDS D
Sbjct: 1181 SDSSDSSDSSDS-SDSSDSSDSSDSSDSSDSSD 1212
Score = 35.0 bits (79), Expect = 0.42
Identities = 23/98 (23%), Positives = 43/98 (43%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ S S SDS + + S+SSD S S D+ SS + +
Sbjct: 1175 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNES 1234
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKE 1158
+ +SDS +S + + ++ S+SDS+D+ +
Sbjct: 1235 SDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQ 1272
Score = 34.7 bits (78), Expect = 0.55
Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Query: 1066 ESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTS 1125
+S+S SDS + + S+SSD SSS D+ +SS + ++ +
Sbjct: 644 DSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSD 703
Query: 1126 ASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKE 1158
+SDS +S + ++ S+SSDSD +
Sbjct: 704 SSDSSDSDSS---DSSDSSNSNSSDSDSSNSSD 733
Score = 34.7 bits (78), Expect = 0.55
Identities = 25/94 (26%), Positives = 45/94 (47%), Gaps = 1/94 (1%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ + S S SDS + + S+SSD S+S D+ SS + ++
Sbjct: 741 SDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNS 800
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSS-SSDSDD 1153
+++SDS +S + + ++ SS SSDS D
Sbjct: 801 SDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSD 834
Score = 34.7 bits (78), Expect = 0.55
Identities = 18/61 (29%), Positives = 32/61 (52%)
Query: 1094 SESSDGSSSEDAESSSLMNVQRRTAAKEPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
S+SSD S+S D+ SS + ++ + +SDS +S + N +++SS SD
Sbjct: 912 SDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS 971
Query: 1154 D 1154
+
Sbjct: 972 N 972
Score = 34.7 bits (78), Expect = 0.55
Identities = 23/98 (23%), Positives = 42/98 (42%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ S S SDS + + S+SSD S+S D+ +SS + ++
Sbjct: 977 SDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS 1036
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKE 1158
+ +SDS +S + N ++ SS SD +
Sbjct: 1037 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD 1074
Score = 34.7 bits (78), Expect = 0.55
Identities = 24/93 (25%), Positives = 45/93 (48%), Gaps = 1/93 (1%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+N+ + S+S SDS + + S+SSD S+S D+ SS + ++
Sbjct: 1016 SNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1075
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+ +S+S +S ++ + + +S SSDS D
Sbjct: 1076 SDSSDSSESSDS-SDSSNSSDSSDSSDSSDSSD 1107
Score = 34.7 bits (78), Expect = 0.55
Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 1/93 (1%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ + S S SDS + + S+SSD S S D+ SS + ++
Sbjct: 1037 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDS 1096
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+ +SDS +S ++ + + +S+SSDS D
Sbjct: 1097 SDSSDSSDSSDS-SDSSDSSDSSDSSNSSDSSD 1128
Score = 34.7 bits (78), Expect = 0.55
Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ + S S SDS + + S+SSD S S D+ SS + ++
Sbjct: 1154 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1213
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+ +SDS +S ++ N + +S SSDS D
Sbjct: 1214 SDSSDSSDSSDS-SDSSDSNESSDSSDSSDSSD 1245
Score = 34.3 bits (77), Expect = 0.72
Identities = 24/93 (25%), Positives = 49/93 (52%), Gaps = 2/93 (2%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+N+ + S+S SDS + + S+SSD +SS+ ++SS+ + + +
Sbjct: 933 SNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+ + +SDS NS ++ + + +S+SSDS +
Sbjct: 993 D-SSDSSDSSNS-SDSSDSSDSSDSSNSSDSSN 1023
Score = 34.3 bits (77), Expect = 0.72
Identities = 24/95 (25%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ + S S SDS + + S+SSD S S D+ SS + ++
Sbjct: 1004 SDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1063
Query: 1121 EPKTSASDSQNS--VKEAPVKNGGATTSSSSDSDD 1153
+ +SDS +S ++ + + +S+SSDS D
Sbjct: 1064 SDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSD 1098
Score = 34.3 bits (77), Expect = 0.72
Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ + S S SDS + + S+SSD S S D+ SS + ++
Sbjct: 1130 SDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1189
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+ +SDS +S ++ + + +S SSDS D
Sbjct: 1190 SDSSDSSDSSDS-SDSSDSSDSSDSSDSSDSSD 1221
Score = 34.3 bits (77), Expect = 0.72
Identities = 26/100 (26%), Positives = 42/100 (42%), Gaps = 2/100 (2%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ + S S SDS + + S+SSD S S D+ SS + ++
Sbjct: 1169 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1228
Query: 1121 EPKTSASDSQNSVKEAPVKNG--GATTSSSSDSDDDGGKE 1158
+SDS +S + N + +S SSDS D E
Sbjct: 1229 SDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDE 1268
Score = 34.3 bits (77), Expect = 0.72
Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 4/99 (4%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGS----SSEDAESSSLMNVQRR 1116
+++ + S S SDS + + S+SSD + SS+ ++SS N
Sbjct: 1193 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDS 1252
Query: 1117 TAAKEPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDG 1155
+ + + S SDS + G S SDSD +G
Sbjct: 1253 SDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEG 1291
Score = 33.9 bits (76), Expect = 0.95
Identities = 23/110 (20%), Positives = 50/110 (45%), Gaps = 1/110 (0%)
Query: 1049 DKAKRKTQKRGITNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESS 1108
D K K+ +++ + S+S SDS ++ ++ S+SSD S S+ ++SS
Sbjct: 541 DSGKGKSDSSD-SDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSS 599
Query: 1109 SLMNVQRRTAAKEPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKE 1158
+ + + + + S+ S + + ++ + + S SDS D +
Sbjct: 600 NSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSD 649
Score = 33.9 bits (76), Expect = 0.95
Identities = 23/105 (21%), Positives = 46/105 (43%)
Query: 1049 DKAKRKTQKRGITNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESS 1108
D ++ ++ + S SDS + + S+SSD S S D+ SS
Sbjct: 621 DSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSS 680
Query: 1109 SLMNVQRRTAAKEPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
S + ++ +++S+S +S + + ++ SS+S+S D
Sbjct: 681 SDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSD 725
Score = 33.9 bits (76), Expect = 0.95
Identities = 22/93 (23%), Positives = 39/93 (41%)
Query: 1066 ESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTS 1125
+S S SDS + + S+SSD S S ++ SS + ++ +
Sbjct: 725 DSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 784
Query: 1126 ASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKE 1158
++DS NS + N +++SS SD +
Sbjct: 785 SNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSD 817
Score = 33.9 bits (76), Expect = 0.95
Identities = 23/98 (23%), Positives = 41/98 (41%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ + S S SDS + + S+SSD S S D+ SS + ++
Sbjct: 1061 SDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1120
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKE 1158
+ +SDS +S + N ++ SS SD +
Sbjct: 1121 SNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSD 1158
Score = 33.9 bits (76), Expect = 0.95
Identities = 22/98 (22%), Positives = 43/98 (43%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ + S S SDS + + S+SSD S S D+ SS + ++
Sbjct: 1160 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1219
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKE 1158
+ +SDS +S + + + ++ SS+ SD +
Sbjct: 1220 SDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSD 1257
Score = 33.5 bits (75), Expect = 1.2
Identities = 22/83 (26%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Query: 1076 SDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTSASDSQNSVKE 1135
SDSK ++ + S+SSD S+S ++ SS + +++ +++SDS +S +
Sbjct: 636 SDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS-SD 694
Query: 1136 APVKNGGATTSSSSDSDDDGGKE 1158
+ + + +S SSDSD +
Sbjct: 695 SSNSSESSDSSDSSDSDSSDSSD 717
Score = 33.5 bits (75), Expect = 1.2
Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
Query: 1065 EESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKT 1124
+ S S SDS + + S SSD S S D+ +SS ++ +
Sbjct: 655 DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSS-------ESSDSSDS 707
Query: 1125 SASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
S SDS +S + + + +S+SSDS D
Sbjct: 708 SDSDSSDSSDSSNSNSSDSDSSNSSDSSD 736
Score = 33.5 bits (75), Expect = 1.2
Identities = 21/61 (34%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
Query: 1094 SESSDGSSSEDAESSSLMNVQRRTAAKEPKTSASDSQNSVKEAPVKNGGATTSS-SSDSD 1152
S SSD S+S D+ +SS + ++ +++SDS NS + + ++ SS SSDS
Sbjct: 927 SNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSS 986
Query: 1153 D 1153
D
Sbjct: 987 D 987
Score = 33.5 bits (75), Expect = 1.2
Identities = 22/98 (22%), Positives = 42/98 (42%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ + S S SDS + + S SSD S+S D+ +SS + ++
Sbjct: 983 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDS 1042
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKE 1158
+ +SDS +S + + ++ SS SD +
Sbjct: 1043 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1080
Score = 33.5 bits (75), Expect = 1.2
Identities = 22/98 (22%), Positives = 42/98 (42%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ + S S SDS + + S+SSD S S D+ SS + ++
Sbjct: 1034 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNS 1093
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKE 1158
+ +SDS +S + + ++ SS+ SD +
Sbjct: 1094 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1131
Score = 33.5 bits (75), Expect = 1.2
Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ + S S SDS + + S+SSD S S D+ SS + ++
Sbjct: 1127 SDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1186
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+ +SDS +S ++ + + +S SSDS D
Sbjct: 1187 SDSSDSSDSSDS-SDSSDSSDSSDSSDSSDSSD 1218
Score = 33.1 bits (74), Expect = 1.6
Identities = 22/92 (23%), Positives = 39/92 (42%)
Query: 1067 SSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTSA 1126
SS SDS + + S SSD S S D+ +SS + ++ +++
Sbjct: 723 SSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS 782
Query: 1127 SDSQNSVKEAPVKNGGATTSSSSDSDDDGGKE 1158
SDS +S + + ++ SS+ SD +
Sbjct: 783 SDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSD 814
Score = 33.1 bits (74), Expect = 1.6
Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+N+ + S S SDS + S+SSD S+S D+ +SS + ++
Sbjct: 762 SNSSDSSDSSDSSDSSDSSNSSDSNDSSNS---SDSSDSSNSSDSSNSS-DSSDSSDSSD 817
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSD 1152
+++SDS NS + N ++ SS SD
Sbjct: 818 SDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSD 849
Score = 33.1 bits (74), Expect = 1.6
Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 1/90 (1%)
Query: 1065 EESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSED-AESSSLMNVQRRTAAKEPK 1123
+ S S SDS + + S SSD S+S D ++SS N + + +
Sbjct: 904 DSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSS 963
Query: 1124 TSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
S+ S ++ ++ + + +S SSDS D
Sbjct: 964 NSSDSSDSNSSDSSDSSNSSDSSDSSDSSD 993
Score = 33.1 bits (74), Expect = 1.6
Identities = 24/87 (27%), Positives = 40/87 (45%), Gaps = 1/87 (1%)
Query: 1067 SSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTSA 1126
SS SDS + + S+SSD S S ++ SS + ++ +++
Sbjct: 965 SSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNS 1024
Query: 1127 SDSQNSVKEAPVKNGGATTSSSSDSDD 1153
SDS NS ++ + + +S SSDS D
Sbjct: 1025 SDSSNS-SDSSDSSDSSDSSDSSDSSD 1050
Score = 33.1 bits (74), Expect = 1.6
Identities = 23/93 (24%), Positives = 44/93 (47%), Gaps = 1/93 (1%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ + S+S SDS + + S+SSD S S ++ SS + ++
Sbjct: 974 SDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDS 1033
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+ +SDS +S ++ + + +S SSDS D
Sbjct: 1034 SDSSDSSDSSDS-SDSSDSSDSSNSSDSSDSSD 1065
Score = 33.1 bits (74), Expect = 1.6
Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 1/93 (1%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ S S SDS + + S+SSD S S D+ SS + ++
Sbjct: 998 SDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1057
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+ +SDS +S ++ + + +S SSDS D
Sbjct: 1058 SDSSDSSDSSDS-SDSSDSSDSSDSSESSDSSD 1089
Score = 33.1 bits (74), Expect = 1.6
Identities = 23/93 (24%), Positives = 44/93 (47%), Gaps = 1/93 (1%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ + S S + SDS + + S+SSD S S D+ SS + ++
Sbjct: 1073 SDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1132
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+ +S+S +S ++ + + +S SSDS D
Sbjct: 1133 SDSSDSSNSSDS-SDSSESSDSSDSSDSSDSSD 1164
Score = 32.7 bits (73), Expect = 2.1
Identities = 26/95 (27%), Positives = 47/95 (49%), Gaps = 5/95 (5%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+N+ E S S SDS ++ + S+SS+ S S D+ +SS + ++
Sbjct: 696 SNSSESSDSSDS---SDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNS 752
Query: 1121 EPKTSASDSQNSV--KEAPVKNGGATTSSSSDSDD 1153
+ +SDS NS ++ + + +S+SSDS+D
Sbjct: 753 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSND 787
Score = 32.7 bits (73), Expect = 2.1
Identities = 24/95 (25%), Positives = 38/95 (40%), Gaps = 2/95 (2%)
Query: 1066 ESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTS 1125
+SS SDS + + S SSD S S D+ S + R+ + S
Sbjct: 808 DSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDS 867
Query: 1126 --ASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKE 1158
+SDS NS + + +++SS SD +
Sbjct: 868 SDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSD 902
Score = 32.7 bits (73), Expect = 2.1
Identities = 21/98 (21%), Positives = 41/98 (41%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ + S S S+S + + S+SSD S S D+ SS + ++
Sbjct: 1067 SDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1126
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKE 1158
+ +SDS +S + + ++ SS SD +
Sbjct: 1127 SDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSD 1164
Score = 32.3 bits (72), Expect = 2.8
Identities = 23/93 (24%), Positives = 39/93 (41%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ S S SDS + + S+SSD S S+ + SS N + +
Sbjct: 777 SDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSS 836
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
S+ S +S + + +S+SSDS D
Sbjct: 837 NSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSD 869
Score = 32.3 bits (72), Expect = 2.8
Identities = 22/92 (23%), Positives = 37/92 (40%)
Query: 1067 SSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTSA 1126
S S SDS + + S SSD S S D+ SS + ++ + +
Sbjct: 974 SDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDS 1033
Query: 1127 SDSQNSVKEAPVKNGGATTSSSSDSDDDGGKE 1158
SDS +S + + ++ SS+ SD +
Sbjct: 1034 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1065
Score = 32.0 bits (71), Expect = 3.6
Identities = 23/79 (29%), Positives = 41/79 (51%), Gaps = 2/79 (2%)
Query: 1076 SDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTSASDSQNS-VK 1134
SDS + + S+SSD S S D++S S + + ++ + K+ +SDS +S
Sbjct: 593 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKS-ESDSSDSDSKSDSSDSNSSDSS 651
Query: 1135 EAPVKNGGATTSSSSDSDD 1153
+ + + +S+SSDS D
Sbjct: 652 DNSDSSDSSNSSNSSDSSD 670
Score = 32.0 bits (71), Expect = 3.6
Identities = 25/94 (26%), Positives = 46/94 (48%), Gaps = 3/94 (3%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGS-SSEDAESSSLMNVQRRTAA 1119
+++ S+S SDS ++ + S+SSD S SSE ++SS + ++
Sbjct: 657 SDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSS 716
Query: 1120 KEPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+++SDS +S + + + +S SSDS D
Sbjct: 717 DSSNSNSSDSDSS--NSSDSSDSSNSSDSSDSSD 748
Score = 32.0 bits (71), Expect = 3.6
Identities = 22/92 (23%), Positives = 40/92 (43%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ + S+S SDS + + S SSD S S D+ SS + ++
Sbjct: 995 SDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1054
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSD 1152
+ +SDS +S + + ++ SS SD
Sbjct: 1055 SNSSDSSDSSDSSDSSDSSDSSDSSDSSESSD 1086
Score = 32.0 bits (71), Expect = 3.6
Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 1/93 (1%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ E S S SDS + + S+SSD S S ++ SS + ++
Sbjct: 1079 SDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1138
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+ +SDS S ++ + + +S SSDS D
Sbjct: 1139 SNSSDSSDSSES-SDSSDSSDSSDSSDSSDSSD 1170
Score = 31.6 bits (70), Expect = 4.7
Identities = 22/98 (22%), Positives = 43/98 (43%), Gaps = 1/98 (1%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+N+ + S S SDS + ++ S SSD S S ++ SS + ++
Sbjct: 939 SNSSDSSDSSDSSNSSDSSNSSDSSNS-SDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDS 997
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKE 1158
+++SDS +S + N +++SS S+ +
Sbjct: 998 SDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 1035
Score = 31.6 bits (70), Expect = 4.7
Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 1/89 (1%)
Query: 1065 EESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKT 1124
+ S S SDS + + S+SSD S+S D+ SS + ++ +
Sbjct: 1086 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSS 1145
Query: 1125 SASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+S+S +S ++ + + +S SSDS D
Sbjct: 1146 DSSESSDS-SDSSDSSDSSDSSDSSDSSD 1173
Score = 31.6 bits (70), Expect = 4.7
Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 1/93 (1%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ S S SDS + + S+SSD S S D+ SS + ++
Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS 1177
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+ +SDS +S ++ + + +S SSDS D
Sbjct: 1178 SNSSDSSDSSDS-SDSSDSSDSSDSSDSSDSSD 1209
Score = 31.6 bits (70), Expect = 4.7
Identities = 22/98 (22%), Positives = 40/98 (40%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ S S SDS + + S+SSD S S ++ SS + ++
Sbjct: 1136 SDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1195
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKE 1158
+ +SDS +S + + ++ SS SD E
Sbjct: 1196 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNE 1233
Score = 31.6 bits (70), Expect = 4.7
Identities = 22/98 (22%), Positives = 40/98 (40%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ E S S SDS + + S SSD S S D+ SS + ++
Sbjct: 1145 SDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1204
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKE 1158
+ +SDS +S + + ++ S+ SD +
Sbjct: 1205 SDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSD 1242
Score = 31.2 bits (69), Expect = 6.1
Identities = 22/70 (31%), Positives = 36/70 (51%), Gaps = 4/70 (5%)
Query: 1094 SESSDGSSSE--DAESSSLMNVQRRTAAKEPKTSASDSQNS--VKEAPVKNGGATTSSSS 1149
S+SSD S S+ D+ SSS + ++ + +SDS NS ++ + + +S SS
Sbjct: 561 SDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSS 620
Query: 1150 DSDDDGGKEK 1159
DS D K +
Sbjct: 621 DSKSDSSKSE 630
Score = 31.2 bits (69), Expect = 6.1
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 4/93 (4%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ + S+S SDS + + S+SSD S S ++ SS ++
Sbjct: 654 SDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESS----DSSDSSD 709
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSSSSDSDD 1153
+ +SDS NS + + +S SS+S D
Sbjct: 710 SDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD 742
Score = 30.8 bits (68), Expect = 8.0
Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 1/94 (1%)
Query: 1061 TNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAK 1120
+++ S S SDS + + +ESS+ S S D+ +SS + + +
Sbjct: 853 SDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSS 912
Query: 1121 EPKTSASDSQNSVKEAPVKNGGATTSS-SSDSDD 1153
+ S++ S +S N ++ SS SSDS D
Sbjct: 913 DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSD 946
Score = 30.8 bits (68), Expect = 8.0
Identities = 22/92 (23%), Positives = 38/92 (41%), Gaps = 1/92 (1%)
Query: 1067 SSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTSA 1126
S S SDS + + S SSD S S ++SS N + + + + +
Sbjct: 936 SDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSD-SSDS 994
Query: 1127 SDSQNSVKEAPVKNGGATTSSSSDSDDDGGKE 1158
SDS +S + + ++ SS+ SD +
Sbjct: 995 SDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSD 1026
>gi|38261962 activating transcription factor 7 interacting protein
[Homo sapiens]
Length = 1270
Score = 43.5 bits (101), Expect = 0.001
Identities = 86/474 (18%), Positives = 179/474 (37%), Gaps = 65/474 (13%)
Query: 334 EPDATPPSPRTLLAMQAALLGSSSEEELESENRRQARGRNAPAAVDEGSISPRTLSAIKR 393
+P ++ P P + ++ ++++ SE APA+ D S
Sbjct: 203 DPTSSDPIPGEPVPVEPISGDCAADDIASSEITSVDLASGAPASTDPASDD--------- 253
Query: 394 ALDDDEDVKVCAGDDVQTGGPGAEEMRINSSTENSDEGLKVRDGKGIPFTATLASSSVNS 453
D A DD+ TG ++E+ S+ + + E V + +P + SS N
Sbjct: 254 LASGDLSSSELASDDLATGELASDELTSESTFDRTFEPKSVPVCEPVPEIDNIEPSS-NK 312
Query: 454 AEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFPISDESMIKDR----KDRLPLESAVVR 509
++ + + K+ + + ++E++ D DR P V
Sbjct: 313 DDDFLEKNGADEKLEQIQSKDSLDEKNKADNNIDANEETLETDDTTICSDRPPENEKKVE 372
Query: 510 HSDAPGLPNGRELTPASPTCTNSV-SKNETHAEVLEQQNELCPYESKFDSSLLSSDDETK 568
L G + +S +++ET A+++E NE ++K ++ L ++D
Sbjct: 373 EDIITELALGEDAISSSMEIDQGEKNEDETSADLVETINENVIEDNKSENILENTDS--- 429
Query: 569 CKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHENFLETIQ--EQQTTES 626
ET I+ + + + + + F+ ET E++ S
Sbjct: 430 ---------------METDEIIPILEKLAPSEDELTCFSKTSLLPIDETNPDLEEKMESS 474
Query: 627 AGQDLISIPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKPPSEQGEEELV 686
G P + +S ES +F+ V+SDEE E+ E E++
Sbjct: 475 FGS----------PSKQESSESLPKEAFL----VLSDEE---------DISGEKDESEVI 511
Query: 687 GTREGEAPAESESLLRDNSERDDVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQ 746
E +PAE ES +DN ++ ++ E+ +E +E+ + E +++ +
Sbjct: 512 SQNETCSPAEVESNEKDNKPEEEEQVIHEDDERPSEK--NEFSRRKRSKSEDMDNVQSKR 569
Query: 747 QNSLKAQKQQQERIAATVTGQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLT 800
+ ++ + + + ++ T G + + Q++ I ++ QCA+ D T
Sbjct: 570 RRYMEEEYEAEFQVKITAKGDINQKLQKV-----IQWLLEEKLCALQCAVFDKT 618
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 43.5 bits (101), Expect = 0.001
Identities = 141/692 (20%), Positives = 268/692 (38%), Gaps = 115/692 (16%)
Query: 119 IKTAFRSKRDEALPSLTQVRRE-NDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQE 177
IKT S+ + L LT+ + N + Q EEK + + + + + + +K+ALQ+
Sbjct: 1266 IKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQK 1325
Query: 178 EFFHNPQAIDIESEDFSSLPPEVKHEI--LTDMKEFTKRRRTLFEAMPEESDDFSQYQLK 235
E + QA + + L E+ I +T MKE K ++ ++ ++ D + QL+
Sbjct: 1326 EGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLN-VQLQ 1384
Query: 236 GLLKKNYLNQHIEHVQKEMNQQH----------SGHIRRQYEDEGGFLKEVE-------- 277
+ + I ++K+ +++ S + +++ L++V+
Sbjct: 1385 NSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSE 1444
Query: 278 -SRRVVSEDTSHYILIKGIQAKTVAEVDSESLPSSSKMHGM---SFDVKSSPCEKLKTEK 333
++ S T H +K +Q + E+ S+ + + D ++ + LK E
Sbjct: 1445 WKKKAQSRFTQHQNTVKELQIQ--LELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEM 1502
Query: 334 EPDATPPSPRTLLAMQAALLGSSSEEELESENRRQARGRNAPAAVDEGSISPRTLSAIKR 393
E D + + S+ E EL+S+ AR + + +I +L+ + +
Sbjct: 1503 EDDKSKMEKKE----------SNLETELKSQT---ARIMELEDHITQKTIEIESLNEVLK 1549
Query: 394 ALDDDEDVKVCAGDDVQTGGPGAEEMRINSSTENSDEGLKVRDGKGIPFTATLASSSVNS 453
+ +D+ E + ++ E + +D + V
Sbjct: 1550 NYNQQKDI---------------EHKELVQKLQHFQELGEEKDNR------------VKE 1582
Query: 454 AEEHVAS-TNEGREPTDSVPKEQMSLVHVGTEAFPISDESMIKDRKDRLPLESA-----V 507
AEE + + N+ + ++ L HV S E +K +DRL ESA +
Sbjct: 1583 AEEKILTLENQVYSMKAELETKKKELEHVNLSV--KSKEEELKALEDRLESESAAKLAEL 1640
Query: 508 VRHSDAPGLPNGRELTPASPTCTNSVSK------NETHAEVLEQQNELCPYESKFDSSLL 561
R ++ ++L K +E + ++ E++ E+ E K S+
Sbjct: 1641 KRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKL-KSVE 1699
Query: 562 SSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHENFLETI-QE 620
SS ET P SA V +E S V + + +V+ N E E L+ + QE
Sbjct: 1700 SSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKI-SVLQRNLTEKEKLLQRVGQE 1758
Query: 621 QQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKPPS-- 678
++ T S+ ++ + I E +E+ E QS+I LQ E E +K S
Sbjct: 1759 KEETVSSHFEMRC---QYQERLIKLEHAEAKQH--EDQSMIG--HLQEELEEKNKKYSLI 1811
Query: 679 -EQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAE----------KDAEDSLHE 727
Q E+ G +A E++ DDV QE E K+ + L
Sbjct: 1812 VAQHVEKEGGKNNIQAKQNLENVF------DDVQKTLQEKELTCQILEQKIKELDSCLVR 1865
Query: 728 WQDINLEELETLESNLLAQQNSLKAQKQQQER 759
++++ E+E L S + L+A +Q R
Sbjct: 1866 QKEVHRVEMEELTS----KYEKLQALQQMDGR 1893
Score = 42.4 bits (98), Expect = 0.003
Identities = 118/641 (18%), Positives = 261/641 (40%), Gaps = 87/641 (13%)
Query: 83 LKKQTLVKRRQRKDLA---SSDSRKTTEKLLKTFLKRQAIKTAFRSKRDEALPSLTQVRR 139
L+K + Q KDLA ++ K +++ K + + + ++D QV +
Sbjct: 576 LEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLK 635
Query: 140 ENDLYVLPPLQE---EEKHSSEEEDEKEWQ---ERMNQKQALQEEFFHNPQAIDIESEDF 193
+ + L+E +EK + ++ E +Q E MN+K + +D++ +
Sbjct: 636 QQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTL---------EKLDVKQTEL 686
Query: 194 SSLPPEVKH---------EILTDMKEFTKRRRTLFEAMPEESDDFSQYQLKGLLKKNYLN 244
SL E+ E L+ +K+ T + + EA +E + Q Q+ ++K++ ++
Sbjct: 687 ESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVS 746
Query: 245 QHIEHVQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVD 304
I+ +K + Q + + ++ LKE H ++ ++A + +
Sbjct: 747 --IQRTEKALKDQIN-QLELLLKERDKHLKE------------HQAHVENLEAD-IKRSE 790
Query: 305 SESLPSSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEELESE 364
E +S+K+ +S+ E+ K +E L +Q LL +E L ++
Sbjct: 791 GELQQASAKLDVFQ-SYQSATHEQTKAYEEQ---------LAQLQQKLLDLETERILLTK 840
Query: 365 N--RRQARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTG----GPGAEE 418
+A+ ++ +D I + L + + + KV + V G +E
Sbjct: 841 QVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQE 900
Query: 419 MRINSSTENSDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSL 478
E + L++R+G+ + + +++ E+ + NE E +++M
Sbjct: 901 QTKQILVEKENMILQMREGQKKEIE--ILTQKLSAKEDSIHILNEEYETKFKNQEKKMEK 958
Query: 479 VHVGTEAFPISDESMIKDRKDRLP--LESAVVRHSDAPGLPNGRELTPA---SPTCTNSV 533
V + + + + D++ +L LE+ + S N + L A S +++V
Sbjct: 959 VKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAV 1018
Query: 534 SKNETHAEVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVP 593
S+ ET+ + EQ L + + ++S ++ + + I + LQE V+
Sbjct: 1019 SRLETNQK--EQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAEL 1076
Query: 594 SEAV-------DNVENVVSFNAKE---HENFLETIQEQQTTESA-----GQDLISIPKAV 638
+ + + + +++ +E + L +QEQ +SA QD + +
Sbjct: 1077 KQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHL 1136
Query: 639 EPMEIDSEESESDGSFIEVQSV----ISDEELQAEFPETSK 675
E +E+D +S + +F++ Q V +++E+ + TSK
Sbjct: 1137 EKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSK 1177
>gi|38176300 nestin [Homo sapiens]
Length = 1621
Score = 43.1 bits (100), Expect = 0.002
Identities = 98/425 (23%), Positives = 177/425 (41%), Gaps = 40/425 (9%)
Query: 81 PLLKKQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAFRSKRDEALPSLTQVRRE 140
P K+ T + +K+ + + K+ E L+TFL S E L SLT + +E
Sbjct: 616 PTGKEDTQTLQSLQKE--NQELMKSLEGNLETFLFPGTENQELVSSLQENLESLTALEKE 673
Query: 141 N----------DLYVLPPLQEEEK---HSSEEEDEKEWQ--ERMNQK--QALQEEFFHNP 183
N D L PL +E + S E+E+++ ++ E+ NQ+ + L+EE
Sbjct: 674 NQEPLRSPEVGDEEALRPLTKENQEPLRSLEDENKEAFRSLEKENQEPLKTLEEEDQSIV 733
Query: 184 QAIDIES-EDFSSLPPEVKHEILTDMKEFTKRRRTLFEAMPEESDDFSQYQLKGLLKKNY 242
+ ++ E+ + SL + + + T KE +RRR+L E ++ + L
Sbjct: 734 RPLETENHKSLRSLEEQDQETLRTLEKETQQRRRSLGE---QDQMTLRPPEKVDLEPLKS 790
Query: 243 LNQHIEHVQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQA-KTVA 301
L+Q I + NQ+ ++ E+ +K +E+ + S ++ ++ +++ +T A
Sbjct: 791 LDQEIARPLENENQE---FLKSLKEESVEAVKSLETEILESLKSAGQENLETLKSPETQA 847
Query: 302 EVDSESLPSSSKMHGMSFDVKSSPCEKLKTEKE-----PDATPPSPRTLLAMQAALLGSS 356
+ + + M+ + +++ P E ++ +E + S R+L A L S
Sbjct: 848 PLWTPEEINQGAMNPLEKEIQ-EPLESVEVNQETFRLLEEENQESLRSLGAWNLENLRSP 906
Query: 357 SEEELESENRRQARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGA 416
E + ES+ + E S R+L + L DV+ D V+ A
Sbjct: 907 EEVDKESQRNLEEEENLGKGEYQE---SLRSLEEEGQELPQSADVQRWE-DTVEKDQELA 962
Query: 417 EEMRIN-SSTENSDEG-LKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKE 474
+E + EN DE L +R+ G + +A E V EG P PKE
Sbjct: 963 QESPPGMAGVENEDEAELNLREQDGFTGKEEVVEQGELNATEEVWIPGEG-HPESPEPKE 1021
Query: 475 QMSLV 479
Q LV
Sbjct: 1022 QRGLV 1026
Score = 42.7 bits (99), Expect = 0.002
Identities = 50/230 (21%), Positives = 98/230 (42%), Gaps = 17/230 (7%)
Query: 535 KNETHAEVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPS 594
+N++H E LE++N+ CP + D L S ++ + EV+ P+ + +
Sbjct: 561 ENQSH-ETLERENQECPRSLEEDLETLKSLEKENKELLKDVEVVRPLEKEAVGQLKPTGK 619
Query: 595 EAVDNVENVVSFNAKEHENFLETIQEQQTT----ESAGQDLI-SIPKAVEPMEIDSEESE 649
E ++++ KE++ +++++ T + Q+L+ S+ + +E + +E++
Sbjct: 620 EDTQTLQSL----QKENQELMKSLEGNLETFLFPGTENQELVSSLQENLESLTALEKENQ 675
Query: 650 SDGSFIEVQSVISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRDNSERDD 709
+ V +E L+ E +P +E R E E++ L+ E D
Sbjct: 676 EP---LRSPEVGDEEALRPLTKENQEPLRSLEDENKEAFRSLE--KENQEPLKTLEEEDQ 730
Query: 710 VDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQER 759
P E E SL ++ + E L TLE ++ SL Q Q R
Sbjct: 731 SIVRPLETEN--HKSLRSLEEQDQETLRTLEKETQQRRRSLGEQDQMTLR 778
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.353
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,084,784
Number of Sequences: 37866
Number of extensions: 2177453
Number of successful extensions: 15076
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 77
Number of HSP's successfully gapped in prelim test: 564
Number of HSP's that attempted gapping in prelim test: 11481
Number of HSP's gapped (non-prelim): 3488
length of query: 1186
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1073
effective length of database: 13,968,660
effective search space: 14988372180
effective search space used: 14988372180
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.