Guide to the Human Genome
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Name: GEN1 Sequence: fasta or formatted (908aa) NCBI GI: 194018535
Description:

Gen homolog 1, endonuclease

Referenced in:

DNases, Recombination, and DNA Repair

Other entries for this name:
alt mRNA [908aa] Gen homolog 1, endonuclease
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             3.7         34           2
 C cysteine            3.6         33           3
 D aspartate           4.8         44           1
 E glutamate           7.4         67           3
 F phenylalanine       2.9         26           2
 G glycine             4.4         40           2
 H histidine           3.6         33           1
 I isoleucine          5.0         45           1
 K lysine              8.6         78           3
 L leucine            10.8         98           3
 M methionine          2.1         19           2
 N asparagine          5.0         45           2
 P proline             5.3         48           2
 Q glutamine           5.2         47           2
 R arginine            4.2         38           1
 S serine             10.2         93           2
 T threonine           4.7         43           2
 V valine              5.1         46           2
 W tryptophan          1.0          9           1
 Y tyrosine            2.4         22           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   Gen homolog 1, endonuclease 
GEN1                  1.000   Gen homolog 1, endonuclease 
FEN1                  0.043   flap structure-specific endonuclease 1 
ERCC5                 0.037   XPG-complementing protein 
EXO1                  0.019   exonuclease 1 isoform b 
EXO1                  0.019   exonuclease 1 isoform a 
EXO1                  0.019   exonuclease 1 isoform b 
MUC16                 0.010   mucin 16 
ASXL3                 0.008   additional sex combs like 3 
LRRC37A3              0.006   leucine rich repeat containing 37, member A3 
INSR                  0.005   insulin receptor isoform Long precursor 
EEA1                  0.005   early endosome antigen 1, 162kD 
NKTR                  0.005   natural killer-tumor recognition sequence 
LOC100294335          0.005   PREDICTED: similar to c114 SLIT-like testicular pro...
LOC100294335          0.005   PREDICTED: similar to c114 SLIT-like testicular pro...
LRRC37A               0.005   leucine rich repeat containing 37A 
LOC100288229          0.005   PREDICTED: hypothetical protein XP_002343606 
LRRC37A2              0.005   c114 SLIT-like testicular protein 
DNTTIP2               0.004   deoxynucleotidyltransferase, terminal, interacting p...
ZMAT1                 0.004   zinc finger, matrin type 1 isoform 1 
ZMAT1                 0.004   zinc finger, matrin type 1 isoform 3 
TRIM48                0.004   tripartite motif-containing 48 
LOC643677             0.004   hypothetical protein LOC643677 
LOC643677             0.004   PREDICTED: hypothetical protein LOC643677 
LOC643677             0.004   PREDICTED: hypothetical protein LOC643677 
LOC643677             0.004   PREDICTED: hypothetical protein LOC643677 
GOLGB1                0.004   golgi autoantigen, golgin subfamily b, macrogolgin ...
TOPORS                0.004   topoisomerase I binding, arginine/serine-rich 
NFAT5                 0.004   nuclear factor of activated T-cells 5 isoform a [Hom...
NFAT5                 0.004   nuclear factor of activated T-cells 5 isoform c [Homo...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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