Guide to the Human Genome
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Name: FEN1 Sequence: fasta or formatted (380aa) NCBI GI: 4758356
Description:

flap structure-specific endonuclease 1

Referenced in:

DNases, Recombination, and DNA Repair

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.2         31           3
 C cysteine            1.6          6           1
 D aspartate           4.2         16           2
 E glutamate          10.0         38           3
 F phenylalanine       3.7         14           2
 G glycine             7.1         27           2
 H histidine           2.1          8           1
 I isoleucine          5.3         20           1
 K lysine             10.0         38           3
 L leucine             9.5         36           2
 M methionine          2.6         10           2
 N asparagine          2.1          8           1
 P proline             4.5         17           2
 Q glutamine           5.3         20           2
 R arginine            5.8         22           2
 S serine              7.1         27           2
 T threonine           3.2         12           2
 V valine              5.3         20           1
 W tryptophan          0.5          2           1
 Y tyrosine            2.1          8           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   flap structure-specific endonuclease 1 
GEN1                  0.107   Gen homolog 1, endonuclease 
GEN1                  0.107   Gen homolog 1, endonuclease 
EXO1                  0.106   exonuclease 1 isoform b 
EXO1                  0.106   exonuclease 1 isoform a 
EXO1                  0.106   exonuclease 1 isoform b 
ERCC5                 0.067   XPG-complementing protein 
GTF2F1                0.010   general transcription factor IIF, polypeptide 1, 74...
CCDC150               0.010   coiled-coil domain containing 150 
LRRC45                0.010   leucine rich repeat containing 45 
IQCD                  0.010   IQ motif containing D 
SPAG5                 0.008   sperm associated antigen 5 
MFAP1                 0.008   microfibrillar-associated protein 1 
RBM16                 0.008   RNA-binding motif protein 16 
BTBD12                0.007   BTB (POZ) domain containing 12 
ARP11                 0.007   PREDICTED: actin-related Arp11 
ARP11                 0.007   PREDICTED: actin-related Arp11 
TRDN                  0.007   triadin 
MGC42105              0.007   serine/threonine-protein kinase NIM1 
CCDC92                0.007   coiled-coil domain containing 92 
PRKG2                 0.006   protein kinase, cGMP-dependent, type II 
PLCB1                 0.006   phosphoinositide-specific phospholipase C beta 1 iso...
PLCB1                 0.006   phosphoinositide-specific phospholipase C beta 1 iso...
LOC390638             0.006   PREDICTED: similar to hCG32587 
ARP11                 0.006   PREDICTED: actin-related Arp11 
LOC100131061          0.006   PREDICTED: similar to golgi autoantigen, golgin sub...
LOC100131061          0.006   PREDICTED: similar to golgi autoantigen, golgin sub...
C9orf144B             0.006   hypothetical protein LOC259308 
KIAA1598              0.006   shootin1 isoform a 
KIAA1598              0.006   shootin1 isoform b 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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