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Search of human proteins with 5031981
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5031981 proteasome 26S subunit, non-ATPase 14 [Homo sapiens]
(310 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5031981 proteasome 26S subunit, non-ATPase 14 [Homo sapiens] 624 e-179
gi|38027923 COP9 signalosome subunit 5 [Homo sapiens] 139 3e-33
gi|4503515 eukaryotic translation initiation factor 3, subunit 3... 65 8e-11
gi|13236583 BRCA1/BRCA2-containing complex, subunit 3 isoform 1 ... 64 2e-10
gi|64762484 BRCA1/BRCA2-containing complex, subunit 3 isoform 2 ... 61 1e-09
gi|148227842 Myb-like, SWIRM and MPN domains 1 [Homo sapiens] 53 3e-07
gi|33147080 STAM binding protein-like 1 [Homo sapiens] 47 3e-05
gi|25777615 proteasome 26S non-ATPase subunit 7 [Homo sapiens] 45 8e-05
gi|71061468 centromere protein E [Homo sapiens] 41 0.002
gi|47132534 STAM binding protein [Homo sapiens] 40 0.003
gi|42519912 STAM binding protein [Homo sapiens] 40 0.003
gi|5453545 STAM binding protein [Homo sapiens] 40 0.003
gi|4503519 eukaryotic translation initiation factor 3, subunit 5... 38 0.013
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 34 0.19
gi|56550043 sarcolemma associated protein [Homo sapiens] 33 0.32
gi|40255029 coiled-coil domain containing 126 [Homo sapiens] 33 0.42
gi|237858799 adenylate kinase domain containing 1 isoform 1 [Hom... 31 1.2
gi|117414154 sodium channel associated protein 2 isoform b [Homo... 31 1.6
gi|117414162 sodium channel associated protein 2 isoform a [Homo... 31 1.6
gi|214010216 SMC6 protein [Homo sapiens] 30 2.1
gi|13375848 SMC6 protein [Homo sapiens] 30 2.1
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 30 2.1
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 30 2.1
gi|4826894 phosphodiesterase 1C [Homo sapiens] 30 2.7
gi|34850061 superiorcervical ganglia, neural specific 10 [Homo s... 30 2.7
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 30 2.7
gi|4502371 breast cancer antiestrogen resistance 3 [Homo sapiens] 30 2.7
gi|51479166 bicaudal D homolog 2 isoform 1 [Homo sapiens] 30 2.7
gi|21735417 bicaudal D homolog 2 isoform 2 [Homo sapiens] 30 2.7
gi|31542699 MPN domain containing isoform 1 [Homo sapiens] 30 3.6
>gi|5031981 proteasome 26S subunit, non-ATPase 14 [Homo sapiens]
Length = 310
Score = 624 bits (1608), Expect = e-179
Identities = 310/310 (100%), Positives = 310/310 (100%)
Query: 1 MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGE 60
MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGE
Sbjct: 1 MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGE 60
Query: 61 FVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGC 120
FVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGC
Sbjct: 61 FVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGC 120
Query: 121 WLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSN 180
WLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSN
Sbjct: 121 WLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSN 180
Query: 181 LGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKH 240
LGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKH
Sbjct: 181 LGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKH 240
Query: 241 NESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCL 300
NESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCL
Sbjct: 241 NESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCL 300
Query: 301 AAMLDTVVFK 310
AAMLDTVVFK
Sbjct: 301 AAMLDTVVFK 310
>gi|38027923 COP9 signalosome subunit 5 [Homo sapiens]
Length = 334
Score = 139 bits (350), Expect = 3e-33
Identities = 86/252 (34%), Positives = 136/252 (53%), Gaps = 20/252 (7%)
Query: 33 ISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQ 92
IS+LALLKM+ H R+G +EVMGLMLG+ VD T+ ++D FA+P GT V A ++
Sbjct: 57 ISALALLKMVMHARSGGNLEVMGLMLGK-VDGETMIIMDSFALPVEGTETRVNAQAAAYE 115
Query: 93 --AKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQS 150
A ++ KQ GR E +GWYHSHPG+GCWLSG+D++TQ + E VAVV+DP ++
Sbjct: 116 YMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRT 175
Query: 151 VK-GKVVIDAFRLINANMMVLGHEPRQ-TTSNLGHLNKPSIQALIHGLNRHYYSITINYR 208
+ GKV + AFR P + T L + + + YY++ ++Y
Sbjct: 176 ISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHC------KQYYALEVSYF 229
Query: 209 KNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAK---------NYNKAV 259
K+ L++K+L L K W+ L+ + + V ++ E + ++ +
Sbjct: 230 KSSLDRKLLELLWNKYWVNTLSSSSLLTNADYTTGQVFDLSEKLEQSEAQLGRGSFMLGL 289
Query: 260 EEEDKMTPEQLA 271
E D+ + ++LA
Sbjct: 290 ETHDRKSEDKLA 301
>gi|4503515 eukaryotic translation initiation factor 3, subunit 3
gamma, 40kDa [Homo sapiens]
Length = 352
Score = 65.1 bits (157), Expect = 8e-11
Identities = 67/282 (23%), Positives = 127/282 (45%), Gaps = 32/282 (11%)
Query: 8 GGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRA-GVPMEVM-GLMLGEFVDDY 65
G G G+G D+ +QV I L +LK++KH + G EV+ G++LG V+D
Sbjct: 20 GAAGKGKGKGGSGDS----AVKQVQIDGLVVLKIIKHYQEEGQGTEVVQGVLLGLVVED- 74
Query: 66 TVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGV 125
+ + + F PQ T + + +Q +M+ L+ + VGWY S +G +++
Sbjct: 75 RLEITNCFPFPQH-TEDDADFDEVQYQMEMMRSLRHVNIDHLHVGWYQS-TYYGSFVTRA 132
Query: 126 DINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLN 185
+++Q S++ E +V ++ DPI++ +G + + A+RL M V ++ + L
Sbjct: 133 LLDSQFSYQHAIEESVVLIYDPIKTAQGSLSLKAYRLTPKLMEVC----KEKDFSPEALK 188
Query: 186 KPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVV 245
K +I + + I + + L ++ L KKS + KH +
Sbjct: 189 KANIT-----FEYMFEEVPIVIKNSHLINVLMWELEKKSAVAD----------KHELLSL 233
Query: 246 KEMLELAKNYNKAVEEEDKMTPE----QLAIKNVGKQDPKRH 283
L KN ++ D+M+ + ++N KQ ++H
Sbjct: 234 ASSNHLGKNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKH 275
>gi|13236583 BRCA1/BRCA2-containing complex, subunit 3 isoform 1
[Homo sapiens]
Length = 316
Score = 63.9 bits (154), Expect = 2e-10
Identities = 54/203 (26%), Positives = 84/203 (41%), Gaps = 51/203 (25%)
Query: 25 VDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDD--------YT---------- 66
V + V++ S A L L H + EVMGL +GE DD YT
Sbjct: 6 VQAVQAVHLESDAFLVCLNHALSTEKEEVMGLCIGELNDDTRSDSKFAYTGTEMRTVAEK 65
Query: 67 ---VRVIDVFAM----------------PQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEM 107
VR++ + ++ P+ + S EA + + TGRP
Sbjct: 66 VDAVRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAER---------LAELTGRPMR 116
Query: 108 VVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVV----VDPIQSVKGKVVIDAFRLI 163
VVGWYHSHP W S VD+ TQ ++ + + V ++ ++ + G+V+ F+ I
Sbjct: 117 VVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSI 176
Query: 164 NANMMVLG-HEPRQTTSNLGHLN 185
A H PR S+ H++
Sbjct: 177 QAQKSSESLHGPRDFWSSSQHIS 199
>gi|64762484 BRCA1/BRCA2-containing complex, subunit 3 isoform 2
[Homo sapiens]
Length = 291
Score = 61.2 bits (147), Expect = 1e-09
Identities = 49/182 (26%), Positives = 76/182 (41%), Gaps = 50/182 (27%)
Query: 25 VDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDD--------YT---------- 66
V + V++ S A L L H + EVMGL +GE DD YT
Sbjct: 6 VQAVQAVHLESDAFLVCLNHALSTEKEEVMGLCIGELNDDTRSDSKFAYTGTEMRTVAEK 65
Query: 67 ---VRVIDVFAM----------------PQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEM 107
VR++ + ++ P+ + S EA + + TGRP
Sbjct: 66 VDAVRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAER---------LAELTGRPMR 116
Query: 108 VVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVV----VDPIQSVKGKVVIDAFRLI 163
VVGWYHSHP W S VD+ TQ ++ + + V ++ ++ + G+V+ F+ I
Sbjct: 117 VVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSI 176
Query: 164 NA 165
A
Sbjct: 177 QA 178
>gi|148227842 Myb-like, SWIRM and MPN domains 1 [Homo sapiens]
Length = 828
Score = 53.1 bits (126), Expect = 3e-07
Identities = 43/122 (35%), Positives = 60/122 (49%), Gaps = 5/122 (4%)
Query: 30 QVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVD-DYTVRVIDVFAMPQSGTGVSVEAVD 88
QV ++S ALL M H + EV+GL+ G + + D V V TG+ E +D
Sbjct: 576 QVKVASEALLIMDLHAHVSMA-EVIGLLGGRYSEVDKVVEVCAAEPCNSLSTGLQCE-MD 633
Query: 89 PVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPI 148
PV Q + + L G V+GWYHSHP F S DI+TQ +++ R A + I
Sbjct: 634 PVSQTQASETLAVRGFS--VIGWYHSHPAFDPNPSLRDIDTQAKYQSYFSRGGAKFIGMI 691
Query: 149 QS 150
S
Sbjct: 692 VS 693
>gi|33147080 STAM binding protein-like 1 [Homo sapiens]
Length = 436
Score = 46.6 bits (109), Expect = 3e-05
Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 13/119 (10%)
Query: 51 MEVMGLMLGEFV-DDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVV 109
+E G++ G+ +++T+ + V +E V+ +F Q + +
Sbjct: 291 IETCGILCGKLTHNEFTITHVIVPKQSAGPDYCDMENVEELFNV-------QDQHDLLTL 343
Query: 110 GWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMM 168
GW H+HP +LS VD++T S++ + A+A+V P G FRL NA M+
Sbjct: 344 GWIHTHPTQTAFLSSVDLHTHCSYQLMLPEAIAIVCSPKHKDTG-----IFRLTNAGML 397
>gi|25777615 proteasome 26S non-ATPase subunit 7 [Homo sapiens]
Length = 324
Score = 45.1 bits (105), Expect = 8e-05
Identities = 36/127 (28%), Positives = 60/127 (47%), Gaps = 17/127 (13%)
Query: 29 EQVYISSLALLKMLKH----GRAGVPMEVMGLMLGEFVDDYTVRVIDV---FAMP--QSG 79
++V + L LL ++ H G+ G V+G++LG + +V+DV FA+P +
Sbjct: 7 QKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGS----WQKKVLDVSNSFAVPFDEDD 62
Query: 80 TGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSER 139
SV +D + M M K+ E +VGWYH+ P L DI + +
Sbjct: 63 KDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPK----LHKNDIAINELMKRYCPN 118
Query: 140 AVAVVVD 146
+V V++D
Sbjct: 119 SVLVIID 125
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 40.8 bits (94), Expect = 0.002
Identities = 33/131 (25%), Positives = 66/131 (50%), Gaps = 11/131 (8%)
Query: 184 LNKPSIQALIHGLNRHYYSITINYRKNELE-QKMLLNLHKKS------WMEGLTLQDYSE 236
LN+ +I++ ++ L Y ++ ++Y + E ++M L L +K+ +E T +D
Sbjct: 491 LNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEM 550
Query: 237 HCKHNESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNI 296
H S +K +++ A+ YN+ +E E E L K+D + L+E++D NI
Sbjct: 551 QLIHEISNLKNLVKHAEVYNQDLENELSSKVELLR----EKEDQIKKLQEYIDSQKLENI 606
Query: 297 VQCLAAMLDTV 307
L+ L+++
Sbjct: 607 KMDLSYSLESI 617
>gi|47132534 STAM binding protein [Homo sapiens]
Length = 424
Score = 40.0 bits (92), Expect = 0.003
Identities = 28/128 (21%), Positives = 58/128 (45%), Gaps = 10/128 (7%)
Query: 23 PAVDTAEQVYISSLALLKMLKHGRAGVP--MEVMGLMLGEFV-DDYTVRVIDVFAMPQSG 79
P +D V + + L+ A +E G++ G+ + +++T+ + +
Sbjct: 249 PTIDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVLIPKQSAGS 308
Query: 80 TGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSER 139
+ E + +F L Q + + +GW H+HP +LS VD++T S++ +
Sbjct: 309 DYCNTENEEELF-------LIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLPE 361
Query: 140 AVAVVVDP 147
+VA+V P
Sbjct: 362 SVAIVCSP 369
>gi|42519912 STAM binding protein [Homo sapiens]
Length = 424
Score = 40.0 bits (92), Expect = 0.003
Identities = 28/128 (21%), Positives = 58/128 (45%), Gaps = 10/128 (7%)
Query: 23 PAVDTAEQVYISSLALLKMLKHGRAGVP--MEVMGLMLGEFV-DDYTVRVIDVFAMPQSG 79
P +D V + + L+ A +E G++ G+ + +++T+ + +
Sbjct: 249 PTIDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVLIPKQSAGS 308
Query: 80 TGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSER 139
+ E + +F L Q + + +GW H+HP +LS VD++T S++ +
Sbjct: 309 DYCNTENEEELF-------LIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLPE 361
Query: 140 AVAVVVDP 147
+VA+V P
Sbjct: 362 SVAIVCSP 369
>gi|5453545 STAM binding protein [Homo sapiens]
Length = 424
Score = 40.0 bits (92), Expect = 0.003
Identities = 28/128 (21%), Positives = 58/128 (45%), Gaps = 10/128 (7%)
Query: 23 PAVDTAEQVYISSLALLKMLKHGRAGVP--MEVMGLMLGEFV-DDYTVRVIDVFAMPQSG 79
P +D V + + L+ A +E G++ G+ + +++T+ + +
Sbjct: 249 PTIDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVLIPKQSAGS 308
Query: 80 TGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSER 139
+ E + +F L Q + + +GW H+HP +LS VD++T S++ +
Sbjct: 309 DYCNTENEEELF-------LIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLPE 361
Query: 140 AVAVVVDP 147
+VA+V P
Sbjct: 362 SVAIVCSP 369
>gi|4503519 eukaryotic translation initiation factor 3, subunit 5
epsilon, 47kDa [Homo sapiens]
Length = 357
Score = 37.7 bits (86), Expect = 0.013
Identities = 21/60 (35%), Positives = 36/60 (60%), Gaps = 2/60 (3%)
Query: 53 VMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWY 112
V+G +LG VD ++V V + F++P + + V AVD F M ++ K+ E+++GWY
Sbjct: 116 VIGTLLGT-VDKHSVEVTNCFSVPHNESEDEV-AVDMEFAKNMYELHKKVSPNELILGWY 173
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 33.9 bits (76), Expect = 0.19
Identities = 22/91 (24%), Positives = 39/91 (42%), Gaps = 5/91 (5%)
Query: 203 ITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEE 262
+++ YR+ LEQ+ L + +W+ E E+LEL N EE
Sbjct: 174 VSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEV 233
Query: 263 DKMTPEQLAIKNVGKQDPKRHLEEHVDVLMT 293
++ + +K HL++HV+ L+T
Sbjct: 234 SRLEEQMNGLKT-----SNEHLQKHVEDLLT 259
>gi|56550043 sarcolemma associated protein [Homo sapiens]
Length = 811
Score = 33.1 bits (74), Expect = 0.32
Identities = 39/149 (26%), Positives = 71/149 (47%), Gaps = 19/149 (12%)
Query: 154 KVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGL--NRHYYSITINYRKNE 211
+ +ID RL++ + V+G++ + + N + S++ + L ++H Y T
Sbjct: 205 QALIDEDRLLS-RLEVMGNQLQACSKNQ---TEDSLRKELIALQEDKHNYETTAKESLRR 260
Query: 212 LEQKMLLNLHKKSWMEGLTLQDYSEHCKH----NESVVKEMLELAKNYNKAVEE----ED 263
+ Q+ + + K S +E +L + + C H NE +E+ ELA YN AV E D
Sbjct: 261 VLQEKIEVVRKLSEVER-SLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSD 319
Query: 264 KM---TPEQLAIKNVGKQDPKRHLEEHVD 289
K+ +Q I+ G Q K+ L+ +D
Sbjct: 320 KLKVAEGKQEEIQQKG-QAEKKELQHKID 347
>gi|40255029 coiled-coil domain containing 126 [Homo sapiens]
Length = 140
Score = 32.7 bits (73), Expect = 0.42
Identities = 29/89 (32%), Positives = 47/89 (52%), Gaps = 5/89 (5%)
Query: 208 RKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVK---EMLELAKNYNKAVEEEDK 264
RKN + QK+ L L + GL L Y+ ++S VK ++L+L+K Y KA+ EE+K
Sbjct: 7 RKN-MSQKLSLLLLVFGLIWGLMLLHYTFQQPRHQSSVKLREQILDLSKRYVKALAEENK 65
Query: 265 MTPE-QLAIKNVGKQDPKRHLEEHVDVLM 292
T + + G D KR + +D ++
Sbjct: 66 NTVDVENGASMAGYADLKRTIAVLLDDIL 94
>gi|237858799 adenylate kinase domain containing 1 isoform 1 [Homo
sapiens]
Length = 1911
Score = 31.2 bits (69), Expect = 1.2
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 17/83 (20%)
Query: 212 LEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPEQLA 271
L++K+LL KK E + E ++ ++ +E+ ELA N VEEE
Sbjct: 1026 LQEKLLLKTEKKVGPE------FEEDSENEQAAKQELEELAIQANVKVEEE--------- 1070
Query: 272 IKNVGKQDPKRHLEEHVDVLMTS 294
N KQ P+ L E +V+ +S
Sbjct: 1071 --NTKKQLPEVQLTEEEEVIKSS 1091
>gi|117414154 sodium channel associated protein 2 isoform b [Homo
sapiens]
Length = 939
Score = 30.8 bits (68), Expect = 1.6
Identities = 31/119 (26%), Positives = 49/119 (41%), Gaps = 11/119 (9%)
Query: 169 VLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEG 228
V GHE Q S+L N+ ++A I L+R + RK L + K
Sbjct: 675 VWGHELAQQGSSLAQ-NRGKLEAQIESLSRENECL----RKTNESDSDALRIKCK----- 724
Query: 229 LTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEH 287
+ D +E + + ++E E K + + E +K T EQL K+ + LE H
Sbjct: 725 -IIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKCTQEQLDEKSSQLDEVLEKLERH 782
>gi|117414162 sodium channel associated protein 2 isoform a [Homo
sapiens]
Length = 1032
Score = 30.8 bits (68), Expect = 1.6
Identities = 31/119 (26%), Positives = 49/119 (41%), Gaps = 11/119 (9%)
Query: 169 VLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEG 228
V GHE Q S+L N+ ++A I L+R + RK L + K
Sbjct: 768 VWGHELAQQGSSLAQ-NRGKLEAQIESLSRENECL----RKTNESDSDALRIKCK----- 817
Query: 229 LTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEH 287
+ D +E + + ++E E K + + E +K T EQL K+ + LE H
Sbjct: 818 -IIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKCTQEQLDEKSSQLDEVLEKLERH 875
>gi|214010216 SMC6 protein [Homo sapiens]
Length = 1091
Score = 30.4 bits (67), Expect = 2.1
Identities = 17/64 (26%), Positives = 32/64 (50%)
Query: 190 QALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEML 249
+ L+ HY + + RKN E + L N+ + ++ TL+D ++ K +V+E +
Sbjct: 700 EELLKRCQLHYKELKMKIRKNISEIRELENIEEHQSVDIATLEDEAQENKSKMKMVEEHM 759
Query: 250 ELAK 253
E K
Sbjct: 760 EQQK 763
>gi|13375848 SMC6 protein [Homo sapiens]
Length = 1091
Score = 30.4 bits (67), Expect = 2.1
Identities = 17/64 (26%), Positives = 32/64 (50%)
Query: 190 QALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEML 249
+ L+ HY + + RKN E + L N+ + ++ TL+D ++ K +V+E +
Sbjct: 700 EELLKRCQLHYKELKMKIRKNISEIRELENIEEHQSVDIATLEDEAQENKSKMKMVEEHM 759
Query: 250 ELAK 253
E K
Sbjct: 760 EQQK 763
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 30.4 bits (67), Expect = 2.1
Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 12/69 (17%)
Query: 228 GLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEE-EDKMTPEQLAIKNVGKQDPKRHLEE 286
G T+QDY + VKE LE K +KA+ E E+KM ++ K+ LE+
Sbjct: 17 GPTIQDYLNRPRPTWEEVKEQLEKKKKGSKALAEFEEKM-----------NENWKKELEK 65
Query: 287 HVDVLMTSN 295
H + L++ +
Sbjct: 66 HREKLLSGS 74
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 30.4 bits (67), Expect = 2.1
Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 12/69 (17%)
Query: 228 GLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEE-EDKMTPEQLAIKNVGKQDPKRHLEE 286
G T+QDY + VKE LE K +KA+ E E+KM ++ K+ LE+
Sbjct: 27 GPTIQDYLNRPRPTWEEVKEQLEKKKKGSKALAEFEEKM-----------NENWKKELEK 75
Query: 287 HVDVLMTSN 295
H + L++ +
Sbjct: 76 HREKLLSGS 84
>gi|4826894 phosphodiesterase 1C [Homo sapiens]
Length = 634
Score = 30.0 bits (66), Expect = 2.7
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 172 HEPRQTTSNLGHLNKPSIQALIHG----LNRHYYSITINYRKNELEQKMLLNLHKKSWME 227
+E TT+N H+ S A+++ L H+ S +++ E +L+NL K W E
Sbjct: 270 YEHTGTTNNF-HIQTRSDPAILYNDRSVLENHHLSAAYRLLQDDEEMNILINLSKDDWRE 328
Query: 228 GLTL 231
TL
Sbjct: 329 FRTL 332
>gi|34850061 superiorcervical ganglia, neural specific 10 [Homo
sapiens]
Length = 179
Score = 30.0 bits (66), Expect = 2.7
Identities = 15/60 (25%), Positives = 32/60 (53%)
Query: 211 ELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPEQL 270
E+++K+ ++ E L+ +E +H V+++ LE N++K EE+ + EQ+
Sbjct: 83 EIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQI 142
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 30.0 bits (66), Expect = 2.7
Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 19/128 (14%)
Query: 197 NRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTL---QDYSEHCKHNESVVKEMLELAK 253
N+H IT+ K++ E + L + W E L + Q +E K E +E L K
Sbjct: 599 NKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLK 658
Query: 254 N----YNKAVEEEDKMTPEQLAIKNVGKQD----------PKRHLEEHVDVL--MTSNIV 297
+ + +EE ++ T E+L +K + + LEE + VL T +
Sbjct: 659 DKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMK 718
Query: 298 QCLAAMLD 305
Q L A +D
Sbjct: 719 QELEAKMD 726
>gi|4502371 breast cancer antiestrogen resistance 3 [Homo sapiens]
Length = 825
Score = 30.0 bits (66), Expect = 2.7
Identities = 20/78 (25%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Query: 183 HLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLL---NLHKKSWMEGLTLQDYSEHC- 238
HL P+++ + RH T K ELE+++LL +L +W G + SE+
Sbjct: 109 HLLDPTVEYVKFSKERHIMDRTPEKLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLV 168
Query: 239 -KHNESVVKEMLELAKNY 255
+ + +V++ L N+
Sbjct: 169 QRDGDFLVRDSLSSPGNF 186
>gi|51479166 bicaudal D homolog 2 isoform 1 [Homo sapiens]
Length = 855
Score = 30.0 bits (66), Expect = 2.7
Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 9/84 (10%)
Query: 219 NLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNY---------NKAVEEEDKMTPEQ 269
++ + + E LQDYSE + N S+ K++ L +N K +EEE + Q
Sbjct: 166 DIKEYKFREARLLQDYSELEEENISLQKQVSVLRQNQVEFEGLKHEIKRLEEETEYLNSQ 225
Query: 270 LAIKNVGKQDPKRHLEEHVDVLMT 293
L K+ +R LEE ++ L T
Sbjct: 226 LEDAIRLKEISERQLEEALETLKT 249
>gi|21735417 bicaudal D homolog 2 isoform 2 [Homo sapiens]
Length = 824
Score = 30.0 bits (66), Expect = 2.7
Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 9/84 (10%)
Query: 219 NLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNY---------NKAVEEEDKMTPEQ 269
++ + + E LQDYSE + N S+ K++ L +N K +EEE + Q
Sbjct: 166 DIKEYKFREARLLQDYSELEEENISLQKQVSVLRQNQVEFEGLKHEIKRLEEETEYLNSQ 225
Query: 270 LAIKNVGKQDPKRHLEEHVDVLMT 293
L K+ +R LEE ++ L T
Sbjct: 226 LEDAIRLKEISERQLEEALETLKT 249
>gi|31542699 MPN domain containing isoform 1 [Homo sapiens]
Length = 471
Score = 29.6 bits (65), Expect = 3.6
Identities = 24/88 (27%), Positives = 42/88 (47%), Gaps = 14/88 (15%)
Query: 52 EVMGLMLGEF-VDDYTVRVIDVFA----MPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPE 106
EV+G + G + V+ + V+ F + + T ++E + ++Q+ L L
Sbjct: 292 EVVGYLGGRWDVNSQMLTVLRAFPCRSRLGDAETAAAIE--EEIYQSLFLRGLS------ 343
Query: 107 MVVGWYHSHPGFGCWLSGVDINTQQSFE 134
+VGWYHSHP S DI+ Q ++
Sbjct: 344 -LVGWYHSHPHSPALPSLQDIDAQMDYQ 370
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,366,247
Number of Sequences: 37866
Number of extensions: 471035
Number of successful extensions: 1647
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 1606
Number of HSP's gapped (non-prelim): 60
length of query: 310
length of database: 18,247,518
effective HSP length: 102
effective length of query: 208
effective length of database: 14,385,186
effective search space: 2992118688
effective search space used: 2992118688
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.