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Search of human proteins with 109150425
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|109150425 ankyrin repeat and zinc finger domain containing 1
[Homo sapiens]
(726 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|109150435 ankyrin repeat and zinc finger domain containing 1 ... 1454 0.0
gi|109150425 ankyrin repeat and zinc finger domain containing 1 ... 1454 0.0
gi|14149716 protein phosphatase 1, regulatory subunit 12C [Homo ... 54 7e-07
gi|10863929 ribonuclease L [Homo sapiens] 49 1e-05
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 48 3e-05
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 48 3e-05
gi|6912326 family with sequence similarity 50, member B [Homo sa... 48 4e-05
gi|154354979 myosin X [Homo sapiens] 47 8e-05
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 45 2e-04
gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo ... 45 3e-04
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 45 3e-04
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 45 3e-04
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 45 3e-04
gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo sa... 45 3e-04
gi|15529978 zinc finger protein 622 [Homo sapiens] 45 3e-04
gi|89941470 ankyrin repeat domain 34 [Homo sapiens] 45 3e-04
gi|62750349 histone deacetylase 5 isoform 3 [Homo sapiens] 44 4e-04
gi|62750347 histone deacetylase 5 isoform 1 [Homo sapiens] 44 4e-04
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 44 5e-04
gi|225543463 tetratricopeptide repeat, ankyrin repeat and coiled... 44 7e-04
gi|225543461 tetratricopeptide repeat, ankyrin repeat and coiled... 44 7e-04
gi|239743649 PREDICTED: IQ motif and ankyrin repeat domain-conta... 44 7e-04
gi|38176283 ankyrin repeat and SOCS box-containing protein 7 iso... 43 0.001
gi|148746195 trichohyalin [Homo sapiens] 43 0.001
gi|30089994 ankyrin repeat and SOCS box-containing protein 7 iso... 43 0.001
gi|55742857 ankyrin repeat domain 6 [Homo sapiens] 43 0.001
gi|30425444 ankyrin repeat and kinase domain containing 1 [Homo ... 42 0.002
gi|55956910 meningioma 1 [Homo sapiens] 42 0.002
gi|21361517 UBX domain protein 1 [Homo sapiens] 42 0.002
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 42 0.002
>gi|109150435 ankyrin repeat and zinc finger domain containing 1
[Homo sapiens]
Length = 726
Score = 1454 bits (3765), Expect = 0.0
Identities = 726/726 (100%), Positives = 726/726 (100%)
Query: 1 MSPAPDAAPAPASISLFDLSADAPVFQGLSLVSHAPGEALARAPRTSCSGSGERESPERK 60
MSPAPDAAPAPASISLFDLSADAPVFQGLSLVSHAPGEALARAPRTSCSGSGERESPERK
Sbjct: 1 MSPAPDAAPAPASISLFDLSADAPVFQGLSLVSHAPGEALARAPRTSCSGSGERESPERK 60
Query: 61 LLQGPMDISEKLFCSTCDQTFQNHQEQREHYKLDWHRFNLKQRLKDKPLLSALDFEKQSS 120
LLQGPMDISEKLFCSTCDQTFQNHQEQREHYKLDWHRFNLKQRLKDKPLLSALDFEKQSS
Sbjct: 61 LLQGPMDISEKLFCSTCDQTFQNHQEQREHYKLDWHRFNLKQRLKDKPLLSALDFEKQSS 120
Query: 121 TGDLSSISGSEDSDSASEEDLQTLDRERATFEKLSRPPGFYPHRVLFQNAQGQFLYAYRC 180
TGDLSSISGSEDSDSASEEDLQTLDRERATFEKLSRPPGFYPHRVLFQNAQGQFLYAYRC
Sbjct: 121 TGDLSSISGSEDSDSASEEDLQTLDRERATFEKLSRPPGFYPHRVLFQNAQGQFLYAYRC 180
Query: 181 VLGPHQDPPEEAELLLQNLQSRGPRDCVVLMAAAGHFAGAIFQGREVVTHKTFHRYTVRA 240
VLGPHQDPPEEAELLLQNLQSRGPRDCVVLMAAAGHFAGAIFQGREVVTHKTFHRYTVRA
Sbjct: 181 VLGPHQDPPEEAELLLQNLQSRGPRDCVVLMAAAGHFAGAIFQGREVVTHKTFHRYTVRA 240
Query: 241 KRGTAQGLRDARGGPSHSAGANLRRYNEATLYKDVRDLLAGPSWAKALEEAGTILLRAPR 300
KRGTAQGLRDARGGPSHSAGANLRRYNEATLYKDVRDLLAGPSWAKALEEAGTILLRAPR
Sbjct: 241 KRGTAQGLRDARGGPSHSAGANLRRYNEATLYKDVRDLLAGPSWAKALEEAGTILLRAPR 300
Query: 301 SGRSLFFGGKGAPLQRGDPRLWDIPLATRRPTFQELQRVLHKLTTLHVYEEDPREAVRLH 360
SGRSLFFGGKGAPLQRGDPRLWDIPLATRRPTFQELQRVLHKLTTLHVYEEDPREAVRLH
Sbjct: 301 SGRSLFFGGKGAPLQRGDPRLWDIPLATRRPTFQELQRVLHKLTTLHVYEEDPREAVRLH 360
Query: 361 SPQTHWKTVREERKKPTEEEIRKICRDEKEALGQNEESPKQGSGSEGEDGFQVELELVEL 420
SPQTHWKTVREERKKPTEEEIRKICRDEKEALGQNEESPKQGSGSEGEDGFQVELELVEL
Sbjct: 361 SPQTHWKTVREERKKPTEEEIRKICRDEKEALGQNEESPKQGSGSEGEDGFQVELELVEL 420
Query: 421 TVGTLDLCESEVLPKRRRRKRNKKEKSRDQEAGAHRTLLQQTQEEEPSTQSSQAVAAPLG 480
TVGTLDLCESEVLPKRRRRKRNKKEKSRDQEAGAHRTLLQQTQEEEPSTQSSQAVAAPLG
Sbjct: 421 TVGTLDLCESEVLPKRRRRKRNKKEKSRDQEAGAHRTLLQQTQEEEPSTQSSQAVAAPLG 480
Query: 481 PLLDEAKAPGQPELWNALLAACRAGDVGVLKLQLAPSPADPRVLSLLSAPLGSGGFTLLH 540
PLLDEAKAPGQPELWNALLAACRAGDVGVLKLQLAPSPADPRVLSLLSAPLGSGGFTLLH
Sbjct: 481 PLLDEAKAPGQPELWNALLAACRAGDVGVLKLQLAPSPADPRVLSLLSAPLGSGGFTLLH 540
Query: 541 AAAAAGRGSVVRLLLEAGADPTVQDSRARPPYTVAADKSTRNEFRRFMEKNPDAYDYNKA 600
AAAAAGRGSVVRLLLEAGADPTVQDSRARPPYTVAADKSTRNEFRRFMEKNPDAYDYNKA
Sbjct: 541 AAAAAGRGSVVRLLLEAGADPTVQDSRARPPYTVAADKSTRNEFRRFMEKNPDAYDYNKA 600
Query: 601 QVPGPLTPEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRAL 660
QVPGPLTPEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRAL
Sbjct: 601 QVPGPLTPEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRAL 660
Query: 661 AAERRLAAQLGAPTSPIPDSAIVNTRRCWSCGASLQGLTPFHYLDFSFCSTRCLQDHRRQ 720
AAERRLAAQLGAPTSPIPDSAIVNTRRCWSCGASLQGLTPFHYLDFSFCSTRCLQDHRRQ
Sbjct: 661 AAERRLAAQLGAPTSPIPDSAIVNTRRCWSCGASLQGLTPFHYLDFSFCSTRCLQDHRRQ 720
Query: 721 AGRPSS 726
AGRPSS
Sbjct: 721 AGRPSS 726
>gi|109150425 ankyrin repeat and zinc finger domain containing 1
[Homo sapiens]
Length = 726
Score = 1454 bits (3765), Expect = 0.0
Identities = 726/726 (100%), Positives = 726/726 (100%)
Query: 1 MSPAPDAAPAPASISLFDLSADAPVFQGLSLVSHAPGEALARAPRTSCSGSGERESPERK 60
MSPAPDAAPAPASISLFDLSADAPVFQGLSLVSHAPGEALARAPRTSCSGSGERESPERK
Sbjct: 1 MSPAPDAAPAPASISLFDLSADAPVFQGLSLVSHAPGEALARAPRTSCSGSGERESPERK 60
Query: 61 LLQGPMDISEKLFCSTCDQTFQNHQEQREHYKLDWHRFNLKQRLKDKPLLSALDFEKQSS 120
LLQGPMDISEKLFCSTCDQTFQNHQEQREHYKLDWHRFNLKQRLKDKPLLSALDFEKQSS
Sbjct: 61 LLQGPMDISEKLFCSTCDQTFQNHQEQREHYKLDWHRFNLKQRLKDKPLLSALDFEKQSS 120
Query: 121 TGDLSSISGSEDSDSASEEDLQTLDRERATFEKLSRPPGFYPHRVLFQNAQGQFLYAYRC 180
TGDLSSISGSEDSDSASEEDLQTLDRERATFEKLSRPPGFYPHRVLFQNAQGQFLYAYRC
Sbjct: 121 TGDLSSISGSEDSDSASEEDLQTLDRERATFEKLSRPPGFYPHRVLFQNAQGQFLYAYRC 180
Query: 181 VLGPHQDPPEEAELLLQNLQSRGPRDCVVLMAAAGHFAGAIFQGREVVTHKTFHRYTVRA 240
VLGPHQDPPEEAELLLQNLQSRGPRDCVVLMAAAGHFAGAIFQGREVVTHKTFHRYTVRA
Sbjct: 181 VLGPHQDPPEEAELLLQNLQSRGPRDCVVLMAAAGHFAGAIFQGREVVTHKTFHRYTVRA 240
Query: 241 KRGTAQGLRDARGGPSHSAGANLRRYNEATLYKDVRDLLAGPSWAKALEEAGTILLRAPR 300
KRGTAQGLRDARGGPSHSAGANLRRYNEATLYKDVRDLLAGPSWAKALEEAGTILLRAPR
Sbjct: 241 KRGTAQGLRDARGGPSHSAGANLRRYNEATLYKDVRDLLAGPSWAKALEEAGTILLRAPR 300
Query: 301 SGRSLFFGGKGAPLQRGDPRLWDIPLATRRPTFQELQRVLHKLTTLHVYEEDPREAVRLH 360
SGRSLFFGGKGAPLQRGDPRLWDIPLATRRPTFQELQRVLHKLTTLHVYEEDPREAVRLH
Sbjct: 301 SGRSLFFGGKGAPLQRGDPRLWDIPLATRRPTFQELQRVLHKLTTLHVYEEDPREAVRLH 360
Query: 361 SPQTHWKTVREERKKPTEEEIRKICRDEKEALGQNEESPKQGSGSEGEDGFQVELELVEL 420
SPQTHWKTVREERKKPTEEEIRKICRDEKEALGQNEESPKQGSGSEGEDGFQVELELVEL
Sbjct: 361 SPQTHWKTVREERKKPTEEEIRKICRDEKEALGQNEESPKQGSGSEGEDGFQVELELVEL 420
Query: 421 TVGTLDLCESEVLPKRRRRKRNKKEKSRDQEAGAHRTLLQQTQEEEPSTQSSQAVAAPLG 480
TVGTLDLCESEVLPKRRRRKRNKKEKSRDQEAGAHRTLLQQTQEEEPSTQSSQAVAAPLG
Sbjct: 421 TVGTLDLCESEVLPKRRRRKRNKKEKSRDQEAGAHRTLLQQTQEEEPSTQSSQAVAAPLG 480
Query: 481 PLLDEAKAPGQPELWNALLAACRAGDVGVLKLQLAPSPADPRVLSLLSAPLGSGGFTLLH 540
PLLDEAKAPGQPELWNALLAACRAGDVGVLKLQLAPSPADPRVLSLLSAPLGSGGFTLLH
Sbjct: 481 PLLDEAKAPGQPELWNALLAACRAGDVGVLKLQLAPSPADPRVLSLLSAPLGSGGFTLLH 540
Query: 541 AAAAAGRGSVVRLLLEAGADPTVQDSRARPPYTVAADKSTRNEFRRFMEKNPDAYDYNKA 600
AAAAAGRGSVVRLLLEAGADPTVQDSRARPPYTVAADKSTRNEFRRFMEKNPDAYDYNKA
Sbjct: 541 AAAAAGRGSVVRLLLEAGADPTVQDSRARPPYTVAADKSTRNEFRRFMEKNPDAYDYNKA 600
Query: 601 QVPGPLTPEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRAL 660
QVPGPLTPEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRAL
Sbjct: 601 QVPGPLTPEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRAL 660
Query: 661 AAERRLAAQLGAPTSPIPDSAIVNTRRCWSCGASLQGLTPFHYLDFSFCSTRCLQDHRRQ 720
AAERRLAAQLGAPTSPIPDSAIVNTRRCWSCGASLQGLTPFHYLDFSFCSTRCLQDHRRQ
Sbjct: 661 AAERRLAAQLGAPTSPIPDSAIVNTRRCWSCGASLQGLTPFHYLDFSFCSTRCLQDHRRQ 720
Query: 721 AGRPSS 726
AGRPSS
Sbjct: 721 AGRPSS 726
>gi|14149716 protein phosphatase 1, regulatory subunit 12C [Homo
sapiens]
Length = 782
Score = 53.5 bits (127), Expect = 7e-07
Identities = 49/146 (33%), Positives = 65/146 (44%), Gaps = 7/146 (4%)
Query: 535 GFTLLHAAAAAGRGSVVRLLLEAGADPTVQDSRARPPYTVAADKSTRNEFRRFMEKNPDA 594
G + LH AAA G V+RLLL+AG DP ++D P AA + R E
Sbjct: 227 GASALHVAAAKGYIEVMRLLLQAGYDPELRDGDGWTPLHAAAHWGVEDACRLLAEHGGGM 286
Query: 595 YDYNKA-QVPGPLT-PEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAA- 651
A Q P L E+ + R+Q+ R Q+E Q R QE + + RR +
Sbjct: 287 DSLTHAGQRPCDLADEEVLSLLEELARKQEDLRNQKEASQSRGQEPQAPSSSKHRRSSVC 346
Query: 652 -LSDREK---RALAAERRLAAQLGAP 673
LS REK + L+ ERR G P
Sbjct: 347 RLSSREKISLQDLSKERRPGGAGGPP 372
Score = 35.8 bits (81), Expect = 0.14
Identities = 39/148 (26%), Positives = 56/148 (37%), Gaps = 16/148 (10%)
Query: 499 LAACRAGDVGVLKLQLAPS---------PADPRVLSLLSAPLGSGGFTLLHAAAAAGRGS 549
LAAC GD+ +L L + PA P + + G + LH A
Sbjct: 56 LAACAGGDLDEARLMLRAADPGPGAELDPAAPPPARAVLDSTNADGISALHQACIDENLE 115
Query: 550 VVRLLLEAGADPTVQDSRARPPYTVAADKSTRNEFRRFMEKNPDAYDYNK-AQVPGPLTP 608
VVR L+E GA D+ P VAA + R + + N +P L
Sbjct: 116 VVRFLVEQGATVNQADNEGWTPLHVAASCGYLDIARYLLSHGANIAAVNSDGDLPLDLAE 175
Query: 609 E------MEARQATRKREQKAARRQREE 630
++A A R + +AA+R EE
Sbjct: 176 SDAMEGLLKAEIARRGVDVEAAKRAEEE 203
>gi|10863929 ribonuclease L [Homo sapiens]
Length = 741
Score = 49.3 bits (116), Expect = 1e-05
Identities = 40/140 (28%), Positives = 64/140 (45%), Gaps = 5/140 (3%)
Query: 534 GGFTLLHAAAAAGRGSVVRLLLEAGADPTVQDSRARPPYTVAADKSTRNEFRRFMEKNPD 593
GG+T LH A R +V LLL GADP ++ P+ +AA + + F+ K D
Sbjct: 58 GGWTPLHNAVQMSREDIVELLLRHGADPVLRKKNGATPFILAAIAGSVKLLKLFLSKGAD 117
Query: 594 AYDYNKAQVPGPLTPEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALS 653
N+ G T MEA + + K ++ R++ +E++ER + AL
Sbjct: 118 V---NECDFYG-FTAFMEAAVYGKVKALKFLYKRGANVNLRRKTKEDQERLRKGGATALM 173
Query: 654 D-REKRALAAERRLAAQLGA 672
D EK + + L ++GA
Sbjct: 174 DAAEKGHVEVLKILLDEMGA 193
Score = 37.4 bits (85), Expect = 0.050
Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 9/97 (9%)
Query: 497 ALLAACRAGDVGVLKLQLAPSPADPRVLSLLSAPLGSGGFTLLHAAAAAGRGSV---VRL 553
AL+ A G V VLK+ L AD ++A G L+HA ++ V L
Sbjct: 171 ALMDAAEKGHVEVLKILLDEMGAD------VNACDNMGRNALIHALLSSDDSDVEAITHL 224
Query: 554 LLEAGADPTVQDSRARPPYTVAADKSTRNEFRRFMEK 590
LL+ GAD V+ R + P +A +K +R +E+
Sbjct: 225 LLDHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQ 261
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 48.1 bits (113), Expect = 3e-05
Identities = 25/58 (43%), Positives = 38/58 (65%), Gaps = 2/58 (3%)
Query: 611 EARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSD--REKRALAAERRL 666
EA++ +REQ+ ++R EQ++R+QE+ E+ER EQ R A + RE+ L AER L
Sbjct: 680 EAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAEREL 737
Score = 38.5 bits (88), Expect = 0.022
Identities = 29/103 (28%), Positives = 46/103 (44%), Gaps = 14/103 (13%)
Query: 581 RNEFRRFMEKNPDAYDYNKAQVPGPLTPEMEARQATRKREQKAARRQREEQQQRQQEQEE 640
R + E+ + AQ+ E R A K ++KAA ++ EE + R++++EE
Sbjct: 585 RERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEE 644
Query: 641 RER-------EEQRRFAALSDREK-------RALAAERRLAAQ 669
R EE+RR L ++K R A +RLA Q
Sbjct: 645 ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQ 687
Score = 37.7 bits (86), Expect = 0.038
Identities = 17/57 (29%), Positives = 32/57 (56%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERR 665
E E + + E K QRE++++ Q+ +E+ RE++RR ++E++ ERR
Sbjct: 669 EEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR 725
Score = 37.7 bits (86), Expect = 0.038
Identities = 21/59 (35%), Positives = 33/59 (55%), Gaps = 6/59 (10%)
Query: 611 EARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRLAAQ 669
E ++ RK + ++ EQ++R+QE+ E+ER EQ R RE+ ER+LA Q
Sbjct: 670 EEQERLRKAAEAKRLAEQREQERREQERREQERREQER------REQERREQERQLAEQ 722
Score = 37.0 bits (84), Expect = 0.065
Identities = 16/62 (25%), Positives = 35/62 (56%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRLAA 668
E E R+ R+ +++ + +RE+++Q +++ RE+E + L +REK + +L
Sbjct: 694 EQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQR 753
Query: 669 QL 670
+L
Sbjct: 754 EL 755
Score = 35.4 bits (80), Expect = 0.19
Identities = 25/99 (25%), Positives = 48/99 (48%), Gaps = 7/99 (7%)
Query: 578 KSTRNEFRRFMEKNPDAYDYNKAQVPGP---LTPEMEARQATRKREQKAAR----RQREE 630
K +F + EK A + A+ +ME +A RK+E++A R +Q EE
Sbjct: 597 KQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE 656
Query: 631 QQQRQQEQEEREREEQRRFAALSDREKRALAAERRLAAQ 669
+++ Q+ ++++ EEQ R ++ ++ A E+ Q
Sbjct: 657 ERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQ 695
Score = 33.1 bits (74), Expect = 0.93
Identities = 22/61 (36%), Positives = 38/61 (62%), Gaps = 2/61 (3%)
Query: 609 EMEARQATRK-REQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRLA 667
E E QA R+ +E++ A R ++EQ QR+ E E++++EEQ+R A +E++ A+
Sbjct: 727 EQERLQAERELQEREKALRLQKEQLQRELE-EKKKKEEQQRLAERQLQEEQEKKAKEAAG 785
Query: 668 A 668
A
Sbjct: 786 A 786
Score = 32.3 bits (72), Expect = 1.6
Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 6/95 (6%)
Query: 609 EMEARQATRKREQKAARRQREEQQQR-----QQEQEEREREEQRRFAALSDREKRALAAE 663
E + + R+REQ+ + +RE Q++ Q+EQ +RE EE+++ +R L E
Sbjct: 716 ERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEE 775
Query: 664 RRLAAQLGAPTSPIPDSAI-VNTRRCWSCGASLQG 697
+ A+ A S + + V + C S + QG
Sbjct: 776 QEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQG 810
Score = 32.0 bits (71), Expect = 2.1
Identities = 47/190 (24%), Positives = 72/190 (37%), Gaps = 24/190 (12%)
Query: 298 APRSGRSLFFGGKGAPLQRGDPRLWDIPLATRRPTFQELQRVLHKLTTLHVYEEDPREAV 357
APRS F + PL R DP+ +F E +R +L L EE E +
Sbjct: 511 APRSVMKSFIK-RNTPL-RMDPKC----------SFVEKER--QRLENLRRKEE--AEQL 554
Query: 358 RLHSPQTHWKTVREERKKPTEEEIRKICRDEKEALGQNEESPKQ--------GSGSEGED 409
R + + EE K EE +RK+ + + EE KQ +E
Sbjct: 555 RRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAK 614
Query: 410 GFQVELELVELTVGTLDLCESEVLPKRRRRKRNKKEKSRDQEAGAHRTLLQQTQEEEPST 469
++ E + + E E K+ R + +++E H+ LLQ+ +EEE
Sbjct: 615 EERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQER 674
Query: 470 QSSQAVAAPL 479
A A L
Sbjct: 675 LRKAAEAKRL 684
Score = 30.8 bits (68), Expect = 4.6
Identities = 16/68 (23%), Positives = 33/68 (48%)
Query: 599 KAQVPGPLTPEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKR 658
K P + P+ + R+R + R++ EQ +RQ+ +E++ R + +R ++
Sbjct: 521 KRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRK 580
Query: 659 ALAAERRL 666
L A R+
Sbjct: 581 VLQARERV 588
Score = 30.4 bits (67), Expect = 6.1
Identities = 19/70 (27%), Positives = 37/70 (52%), Gaps = 11/70 (15%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQE----EREREEQRRFAALSD-------REK 657
E E R+ R+ +++ + ++ +Q+R++EQE ERE +E+ + L EK
Sbjct: 699 EQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEK 758
Query: 658 RALAAERRLA 667
+ ++RLA
Sbjct: 759 KKKEEQQRLA 768
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 48.1 bits (113), Expect = 3e-05
Identities = 25/58 (43%), Positives = 38/58 (65%), Gaps = 2/58 (3%)
Query: 611 EARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSD--REKRALAAERRL 666
EA++ +REQ+ ++R EQ++R+QE+ E+ER EQ R A + RE+ L AER L
Sbjct: 676 EAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAEREL 733
Score = 38.5 bits (88), Expect = 0.022
Identities = 29/103 (28%), Positives = 46/103 (44%), Gaps = 14/103 (13%)
Query: 581 RNEFRRFMEKNPDAYDYNKAQVPGPLTPEMEARQATRKREQKAARRQREEQQQRQQEQEE 640
R + E+ + AQ+ E R A K ++KAA ++ EE + R++++EE
Sbjct: 581 RERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEE 640
Query: 641 RER-------EEQRRFAALSDREK-------RALAAERRLAAQ 669
R EE+RR L ++K R A +RLA Q
Sbjct: 641 ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQ 683
Score = 37.7 bits (86), Expect = 0.038
Identities = 17/57 (29%), Positives = 32/57 (56%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERR 665
E E + + E K QRE++++ Q+ +E+ RE++RR ++E++ ERR
Sbjct: 665 EEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR 721
Score = 37.7 bits (86), Expect = 0.038
Identities = 21/59 (35%), Positives = 33/59 (55%), Gaps = 6/59 (10%)
Query: 611 EARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRLAAQ 669
E ++ RK + ++ EQ++R+QE+ E+ER EQ R RE+ ER+LA Q
Sbjct: 666 EEQERLRKAAEAKRLAEQREQERREQERREQERREQER------REQERREQERQLAEQ 718
Score = 37.0 bits (84), Expect = 0.065
Identities = 16/62 (25%), Positives = 35/62 (56%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRLAA 668
E E R+ R+ +++ + +RE+++Q +++ RE+E + L +REK + +L
Sbjct: 690 EQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQR 749
Query: 669 QL 670
+L
Sbjct: 750 EL 751
Score = 35.4 bits (80), Expect = 0.19
Identities = 25/99 (25%), Positives = 48/99 (48%), Gaps = 7/99 (7%)
Query: 578 KSTRNEFRRFMEKNPDAYDYNKAQVPGP---LTPEMEARQATRKREQKAAR----RQREE 630
K +F + EK A + A+ +ME +A RK+E++A R +Q EE
Sbjct: 593 KQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE 652
Query: 631 QQQRQQEQEEREREEQRRFAALSDREKRALAAERRLAAQ 669
+++ Q+ ++++ EEQ R ++ ++ A E+ Q
Sbjct: 653 ERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQ 691
Score = 33.1 bits (74), Expect = 0.93
Identities = 22/61 (36%), Positives = 38/61 (62%), Gaps = 2/61 (3%)
Query: 609 EMEARQATRK-REQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRLA 667
E E QA R+ +E++ A R ++EQ QR+ E E++++EEQ+R A +E++ A+
Sbjct: 723 EQERLQAERELQEREKALRLQKEQLQRELE-EKKKKEEQQRLAERQLQEEQEKKAKEAAG 781
Query: 668 A 668
A
Sbjct: 782 A 782
Score = 32.3 bits (72), Expect = 1.6
Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 6/95 (6%)
Query: 609 EMEARQATRKREQKAARRQREEQQQR-----QQEQEEREREEQRRFAALSDREKRALAAE 663
E + + R+REQ+ + +RE Q++ Q+EQ +RE EE+++ +R L E
Sbjct: 712 ERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEE 771
Query: 664 RRLAAQLGAPTSPIPDSAI-VNTRRCWSCGASLQG 697
+ A+ A S + + V + C S + QG
Sbjct: 772 QEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQG 806
Score = 30.8 bits (68), Expect = 4.6
Identities = 14/57 (24%), Positives = 31/57 (54%)
Query: 610 MEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRL 666
M+ ++ R+R + R++ EQ +RQ+ +E++ R + +R ++ L A R+
Sbjct: 528 MDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERV 584
Score = 30.8 bits (68), Expect = 4.6
Identities = 28/117 (23%), Positives = 45/117 (38%), Gaps = 8/117 (6%)
Query: 371 EERKKPTEEEIRKICRDEKEALGQNEESPKQ--------GSGSEGEDGFQVELELVELTV 422
EE K EE +RK+ + + EE KQ +E ++ E +
Sbjct: 564 EEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKA 623
Query: 423 GTLDLCESEVLPKRRRRKRNKKEKSRDQEAGAHRTLLQQTQEEEPSTQSSQAVAAPL 479
+ E E K+ R + +++E H+ LLQ+ +EEE A A L
Sbjct: 624 AAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRL 680
Score = 30.4 bits (67), Expect = 6.1
Identities = 19/70 (27%), Positives = 37/70 (52%), Gaps = 11/70 (15%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQE----EREREEQRRFAALSD-------REK 657
E E R+ R+ +++ + ++ +Q+R++EQE ERE +E+ + L EK
Sbjct: 695 EQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEK 754
Query: 658 RALAAERRLA 667
+ ++RLA
Sbjct: 755 KKKEEQQRLA 764
>gi|6912326 family with sequence similarity 50, member B [Homo
sapiens]
Length = 325
Score = 47.8 bits (112), Expect = 4e-05
Identities = 37/85 (43%), Positives = 52/85 (61%), Gaps = 15/85 (17%)
Query: 609 EMEARQAT--RKREQKAARRQREE----QQQRQQEQEEREREEQRRFAALS----DREKR 658
+M+ARQ R+RE++ A+RQ E QQ+RQ+EQE+R RE +R+ + LS D + +
Sbjct: 72 DMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQR-RERKRKISCLSFALDDLDDQ 130
Query: 659 ALAAERRLAAQLG----APTSPIPD 679
A AAE R A LG TS +PD
Sbjct: 131 ADAAEARRAGNLGKNPDVDTSFLPD 155
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 46.6 bits (109), Expect = 8e-05
Identities = 27/84 (32%), Positives = 49/84 (58%), Gaps = 2/84 (2%)
Query: 585 RRFMEKNPDAYDYNKAQVPGPLTPEMEARQATRKREQKAARRQREEQQQRQQEQEERERE 644
RRF+ A + K Q+ G + + + KREQ+ ++Q EE++++++E+EERERE
Sbjct: 783 RRFLHLKKAAIVFQK-QLRGQIARRVYRQLLAEKREQEEKKKQ-EEEEKKKREEEERERE 840
Query: 645 EQRRFAALSDREKRALAAERRLAA 668
+RR A L +++ ++ L A
Sbjct: 841 RERREAELRAQQEEETRKQQELEA 864
Score = 33.5 bits (75), Expect = 0.71
Identities = 14/49 (28%), Positives = 27/49 (55%)
Query: 611 EARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRA 659
+ + +KRE++ R+RE ++ + Q+E E +Q+ AL +K A
Sbjct: 824 QEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEA 872
Score = 33.1 bits (74), Expect = 0.93
Identities = 16/66 (24%), Positives = 34/66 (51%)
Query: 581 RNEFRRFMEKNPDAYDYNKAQVPGPLTPEMEARQATRKREQKAARRQREEQQQRQQEQEE 640
R +R+ + + + + K + E E R+ R+R + R Q+EE+ ++QQE E
Sbjct: 805 RRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEA 864
Query: 641 REREEQ 646
++ ++
Sbjct: 865 LQKSQK 870
Score = 31.6 bits (70), Expect = 2.7
Identities = 29/110 (26%), Positives = 53/110 (48%), Gaps = 8/110 (7%)
Query: 337 QRVLHKLTTLHVYEEDPREAV--RLHSPQTHWKTVREERKKPTEEEIRKICRDEKEALGQ 394
+R LH V+++ R + R++ K +EE+KK EEE +K +E+E +
Sbjct: 783 RRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERE 842
Query: 395 NEESPKQGSGSEGEDGFQVELELVELTVGTLDLCESEVLPKRRRRKRNKK 444
E+ + E E Q ELE ++ + E+E+ + ++K NK+
Sbjct: 843 RREAELRAQ-QEEETRKQQELEALQKSQK-----EAELTRELEKQKENKQ 886
Score = 30.8 bits (68), Expect = 4.6
Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 4/99 (4%)
Query: 599 KAQVPGPLTPEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQ--RRFAALSDRE 656
K+Q LT E+E ++ ++ E+ + E QR +EQ+E E ++ D+E
Sbjct: 867 KSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQE 926
Query: 657 KRALAAERRLAAQ--LGAPTSPIPDSAIVNTRRCWSCGA 693
R L E AAQ L + D + N R S G+
Sbjct: 927 LRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGS 965
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 45.4 bits (106), Expect = 2e-04
Identities = 82/363 (22%), Positives = 142/363 (39%), Gaps = 64/363 (17%)
Query: 334 QELQRVLHKLTTLHVYEEDPREAVRLHSPQTH-WKTVREERKKPTEEEIRKICRDEKEAL 392
+++Q++ KL +E+ E +RLH + ++RE +K EEE ++ +E + L
Sbjct: 616 EKMQQLREKLC-----QEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRL 670
Query: 393 GQNEESPKQGSGSEGEDGFQVELELVELTVGTLDLCESEVLPKRRRRKRNKKEKSRDQEA 452
+ Q S ED + E E L K R ++++ R
Sbjct: 671 SWLR-AQVQSSTQADEDQIRAEQEAS--------------LQKLREELESQQKAERASLE 715
Query: 453 GAHRTLLQQTQEEEPSTQSSQAVAAPLGPLLDEAKAPGQPELWNALLAACRAGDVGVLKL 512
+R +L+Q +EE +++ S+ A L+ AK +L L + V L
Sbjct: 716 QKNRQMLEQLKEEIEASEKSEQAA------LNAAKEKALQQLREQLEGERKEA---VATL 766
Query: 513 QLAPSPADPRVLSLLSAPLGSGGFTLLHAAAAAGRGSVVRLLLEAGADPTVQDSRARPPY 572
+ S R+ S L A +L A + +L G V+ + Y
Sbjct: 767 EKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQ---VEHRVHQKSY 823
Query: 573 TVAADK-----------------------STRNEFRRFMEKNPDAYDYN----KAQVPGP 605
VA + + E ++ M K + Y+ +A++ G
Sbjct: 824 HVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGH 883
Query: 606 LTPEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALS-DREKRALAAER 664
LT E+E Q +RE + R+EQ +R ++ R RE++R+ L D E RA +
Sbjct: 884 LTGELERLQRAHERELETV---RQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKA 940
Query: 665 RLA 667
RLA
Sbjct: 941 RLA 943
Score = 30.4 bits (67), Expect = 6.1
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 5/62 (8%)
Query: 611 EARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRLAAQL 670
E +A+ K EQ A +E+ Q+ +EQ E ER+E A++ EK A RL + L
Sbjct: 727 EEIEASEKSEQAALNAAKEKALQQLREQLEGERKE-----AVATLEKEHSAELERLCSSL 781
Query: 671 GA 672
A
Sbjct: 782 EA 783
>gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo
sapiens]
Length = 142
Score = 44.7 bits (104), Expect = 3e-04
Identities = 30/106 (28%), Positives = 51/106 (48%), Gaps = 17/106 (16%)
Query: 561 PTVQDSRARPPYTVAADKSTRNEFRRFMEKNPDAYDYNKAQVPGPLTPEMEARQATRKRE 620
PT++ S A +A KS R E +R EK + E ++ KR
Sbjct: 51 PTLRHSMAG----TSARKSQRREEKRREEKRREE-------------KRREEKRREGKRR 93
Query: 621 QKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRL 666
+K ++ EE+++ ++E+EE E EE+ +L+ RE+ E+RL
Sbjct: 94 EKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRL 139
Score = 31.6 bits (70), Expect = 2.7
Identities = 12/59 (20%), Positives = 32/59 (54%)
Query: 588 MEKNPDAYDYNKAQVPGPLTPEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQ 646
+++ P ++ A + E ++ KR ++ R ++ + +R++++EE+E EE+
Sbjct: 46 VKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEE 104
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 44.7 bits (104), Expect = 3e-04
Identities = 25/71 (35%), Positives = 41/71 (57%), Gaps = 2/71 (2%)
Query: 599 KAQVPGPLTPEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKR 658
K Q+ +E ++ R+R ++ RR+RE ++Q+++EQ RE+EE+RR L R K
Sbjct: 388 KRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKE 447
Query: 659 ALAAERRLAAQ 669
ERR A +
Sbjct: 448 --EEERRRAEE 456
Score = 40.8 bits (94), Expect = 0.004
Identities = 19/58 (32%), Positives = 35/58 (60%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRL 666
E R ++R ++ ARRQ+E +Q+R++++E+R EE R + +RA +RR+
Sbjct: 404 EQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRV 461
Score = 38.9 bits (89), Expect = 0.017
Identities = 30/97 (30%), Positives = 50/97 (51%), Gaps = 12/97 (12%)
Query: 574 VAADKSTRNEFRRFMEKNPDAYDYNKAQVPGPLTPEMEAR-QATRKREQKAARRQREEQQ 632
V + + R +F R ++N + + + Q L E + R Q KR+ A R++R EQQ
Sbjct: 346 VPGESTLRRDFLRLQQENKERSEALRRQ---QLLQEQQLREQEEYKRQLLAERQKRIEQQ 402
Query: 633 QRQ----QEQEEREREEQRRFAALSDREKRALAAERR 665
+ Q +EQ+ RERE +R+ +RE+R E +
Sbjct: 403 KEQRRRLEEQQRREREARRQ----QEREQRRREQEEK 435
Score = 38.1 bits (87), Expect = 0.029
Identities = 21/58 (36%), Positives = 38/58 (65%), Gaps = 5/58 (8%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEERER--EEQRRFAALSDREKRALAAER 664
E + R+ +R+Q+ +R+RE++++R+ E+ ER R EE+RR A + EKR + E+
Sbjct: 411 EQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRA---EEEKRRVEREQ 465
Score = 35.8 bits (81), Expect = 0.14
Identities = 23/62 (37%), Positives = 36/62 (58%), Gaps = 5/62 (8%)
Query: 609 EMEARQAT----RKREQKAARRQREEQQQRQQEQEERE-REEQRRFAALSDREKRALAAE 663
E EAR+ R+REQ+ RR E +++R++E+E R EE+RR + +R L E
Sbjct: 416 EREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEE 475
Query: 664 RR 665
+R
Sbjct: 476 QR 477
Score = 33.9 bits (76), Expect = 0.55
Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 16/85 (18%)
Query: 589 EKNPDAYDYNKAQVPGPLTPEMEA---------------RQATRKREQKAARRQREEQQQ 633
EK+ Y+Y+ ++ PE E R R +++ R + +QQ
Sbjct: 315 EKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQ 374
Query: 634 RQQEQEEREREEQRRFAALSDREKR 658
QEQ+ RE+EE +R L++R+KR
Sbjct: 375 LLQEQQLREQEEYKR-QLLAERQKR 398
Score = 30.8 bits (68), Expect = 4.6
Identities = 14/48 (29%), Positives = 27/48 (56%)
Query: 613 RQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRAL 660
++ R+ E+ RR+ EE+++R +E++ R EQ + E+R L
Sbjct: 432 QEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHL 479
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 44.7 bits (104), Expect = 3e-04
Identities = 25/71 (35%), Positives = 41/71 (57%), Gaps = 2/71 (2%)
Query: 599 KAQVPGPLTPEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKR 658
K Q+ +E ++ R+R ++ RR+RE ++Q+++EQ RE+EE+RR L R K
Sbjct: 388 KRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKE 447
Query: 659 ALAAERRLAAQ 669
ERR A +
Sbjct: 448 --EEERRRAEE 456
Score = 40.8 bits (94), Expect = 0.004
Identities = 19/58 (32%), Positives = 35/58 (60%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRL 666
E R ++R ++ ARRQ+E +Q+R++++E+R EE R + +RA +RR+
Sbjct: 404 EQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRV 461
Score = 38.9 bits (89), Expect = 0.017
Identities = 30/97 (30%), Positives = 50/97 (51%), Gaps = 12/97 (12%)
Query: 574 VAADKSTRNEFRRFMEKNPDAYDYNKAQVPGPLTPEMEAR-QATRKREQKAARRQREEQQ 632
V + + R +F R ++N + + + Q L E + R Q KR+ A R++R EQQ
Sbjct: 346 VPGESTLRRDFLRLQQENKERSEALRRQ---QLLQEQQLREQEEYKRQLLAERQKRIEQQ 402
Query: 633 QRQ----QEQEEREREEQRRFAALSDREKRALAAERR 665
+ Q +EQ+ RERE +R+ +RE+R E +
Sbjct: 403 KEQRRRLEEQQRREREARRQ----QEREQRRREQEEK 435
Score = 38.1 bits (87), Expect = 0.029
Identities = 21/58 (36%), Positives = 38/58 (65%), Gaps = 5/58 (8%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEERER--EEQRRFAALSDREKRALAAER 664
E + R+ +R+Q+ +R+RE++++R+ E+ ER R EE+RR A + EKR + E+
Sbjct: 411 EQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRA---EEEKRRVEREQ 465
Score = 35.8 bits (81), Expect = 0.14
Identities = 23/62 (37%), Positives = 36/62 (58%), Gaps = 5/62 (8%)
Query: 609 EMEARQAT----RKREQKAARRQREEQQQRQQEQEERE-REEQRRFAALSDREKRALAAE 663
E EAR+ R+REQ+ RR E +++R++E+E R EE+RR + +R L E
Sbjct: 416 EREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEE 475
Query: 664 RR 665
+R
Sbjct: 476 QR 477
Score = 33.9 bits (76), Expect = 0.55
Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 16/85 (18%)
Query: 589 EKNPDAYDYNKAQVPGPLTPEMEA---------------RQATRKREQKAARRQREEQQQ 633
EK+ Y+Y+ ++ PE E R R +++ R + +QQ
Sbjct: 315 EKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQ 374
Query: 634 RQQEQEEREREEQRRFAALSDREKR 658
QEQ+ RE+EE +R L++R+KR
Sbjct: 375 LLQEQQLREQEEYKR-QLLAERQKR 398
Score = 30.8 bits (68), Expect = 4.6
Identities = 14/48 (29%), Positives = 27/48 (56%)
Query: 613 RQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRAL 660
++ R+ E+ RR+ EE+++R +E++ R EQ + E+R L
Sbjct: 432 QEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHL 479
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 44.7 bits (104), Expect = 3e-04
Identities = 25/71 (35%), Positives = 41/71 (57%), Gaps = 2/71 (2%)
Query: 599 KAQVPGPLTPEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKR 658
K Q+ +E ++ R+R ++ RR+RE ++Q+++EQ RE+EE+RR L R K
Sbjct: 388 KRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKE 447
Query: 659 ALAAERRLAAQ 669
ERR A +
Sbjct: 448 --EEERRRAEE 456
Score = 40.8 bits (94), Expect = 0.004
Identities = 19/58 (32%), Positives = 35/58 (60%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRL 666
E R ++R ++ ARRQ+E +Q+R++++E+R EE R + +RA +RR+
Sbjct: 404 EQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRV 461
Score = 38.9 bits (89), Expect = 0.017
Identities = 30/97 (30%), Positives = 50/97 (51%), Gaps = 12/97 (12%)
Query: 574 VAADKSTRNEFRRFMEKNPDAYDYNKAQVPGPLTPEMEAR-QATRKREQKAARRQREEQQ 632
V + + R +F R ++N + + + Q L E + R Q KR+ A R++R EQQ
Sbjct: 346 VPGESTLRRDFLRLQQENKERSEALRRQ---QLLQEQQLREQEEYKRQLLAERQKRIEQQ 402
Query: 633 QRQ----QEQEEREREEQRRFAALSDREKRALAAERR 665
+ Q +EQ+ RERE +R+ +RE+R E +
Sbjct: 403 KEQRRRLEEQQRREREARRQ----QEREQRRREQEEK 435
Score = 38.1 bits (87), Expect = 0.029
Identities = 21/58 (36%), Positives = 38/58 (65%), Gaps = 5/58 (8%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEERER--EEQRRFAALSDREKRALAAER 664
E + R+ +R+Q+ +R+RE++++R+ E+ ER R EE+RR A + EKR + E+
Sbjct: 411 EQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRA---EEEKRRVEREQ 465
Score = 35.8 bits (81), Expect = 0.14
Identities = 23/62 (37%), Positives = 36/62 (58%), Gaps = 5/62 (8%)
Query: 609 EMEARQAT----RKREQKAARRQREEQQQRQQEQEERE-REEQRRFAALSDREKRALAAE 663
E EAR+ R+REQ+ RR E +++R++E+E R EE+RR + +R L E
Sbjct: 416 EREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEE 475
Query: 664 RR 665
+R
Sbjct: 476 QR 477
Score = 33.9 bits (76), Expect = 0.55
Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 16/85 (18%)
Query: 589 EKNPDAYDYNKAQVPGPLTPEMEA---------------RQATRKREQKAARRQREEQQQ 633
EK+ Y+Y+ ++ PE E R R +++ R + +QQ
Sbjct: 315 EKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQ 374
Query: 634 RQQEQEEREREEQRRFAALSDREKR 658
QEQ+ RE+EE +R L++R+KR
Sbjct: 375 LLQEQQLREQEEYKR-QLLAERQKR 398
Score = 30.8 bits (68), Expect = 4.6
Identities = 14/48 (29%), Positives = 27/48 (56%)
Query: 613 RQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRAL 660
++ R+ E+ RR+ EE+++R +E++ R EQ + E+R L
Sbjct: 432 QEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHL 479
>gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo
sapiens]
Length = 528
Score = 44.7 bits (104), Expect = 3e-04
Identities = 21/56 (37%), Positives = 36/56 (64%), Gaps = 1/56 (1%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAER 664
E E ++ RK E++ RR+ EE+++ Q+E+E+R REE+ R + E+R + ER
Sbjct: 182 EKEEQEKKRKEEEERRRREEEERERLQKEEEKRRREEEERLRR-EEEERRRIEEER 236
Score = 37.0 bits (84), Expect = 0.065
Identities = 20/61 (32%), Positives = 35/61 (57%), Gaps = 3/61 (4%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRLAA 668
E E R+ +K E+K R+REE+++ ++E+EER R E+ R +++ A + A
Sbjct: 200 EEEERERLQKEEEK---RRREEEERLRREEEERRRIEEERLRLEQQKQQIMAALNSQTAV 256
Query: 669 Q 669
Q
Sbjct: 257 Q 257
Score = 36.6 bits (83), Expect = 0.084
Identities = 18/56 (32%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
Query: 612 ARQATRKREQKAARRQREEQQQRQQEQEER-EREEQRRFAALSDREKRALAAERRL 666
A K EQ+ R++ EE+++R++E+ ER ++EE++R +R +R RR+
Sbjct: 177 ASHKIEKEEQEKKRKEEEERRRREEEERERLQKEEEKRRREEEERLRREEEERRRI 232
>gi|15529978 zinc finger protein 622 [Homo sapiens]
Length = 477
Score = 44.7 bits (104), Expect = 3e-04
Identities = 17/45 (37%), Positives = 29/45 (64%)
Query: 74 CSTCDQTFQNHQEQREHYKLDWHRFNLKQRLKDKPLLSALDFEKQ 118
C TC F++ QR HYK DWHR+NL++++ ++A F+++
Sbjct: 6 CITCRVAFRDADMQRAHYKTDWHRYNLRRKVASMAPVTAEGFQER 50
>gi|89941470 ankyrin repeat domain 34 [Homo sapiens]
Length = 496
Score = 44.7 bits (104), Expect = 3e-04
Identities = 35/115 (30%), Positives = 49/115 (42%), Gaps = 15/115 (13%)
Query: 480 GPLLDEAKAPGQPELWNALLAACRAG-----DVGVLKLQLAPSPADPRVLSLLSAPLGSG 534
G ++E A G+ AL+AACRA + + L ADP + L G
Sbjct: 28 GAYVNEGDAQGE----TALMAACRARYDDPQNKARMVRYLLEQGADPNIADRL------G 77
Query: 535 GFTLLHAAAAAGRGSVVRLLLEAGADPTVQDSRARPPYTVAADKSTRNEFRRFME 589
L+HA A G +V LLL GADP+V+D A D+ R ++
Sbjct: 78 RTALMHACAGGGGAAVASLLLAHGADPSVRDHAGASALVHALDRGDRETLATLLD 132
>gi|62750349 histone deacetylase 5 isoform 3 [Homo sapiens]
Length = 1123
Score = 44.3 bits (103), Expect = 4e-04
Identities = 42/168 (25%), Positives = 77/168 (45%), Gaps = 18/168 (10%)
Query: 551 VRLLLEAGADPTVQDSRARPPYTVAADKSTRNE---FRRFMEKNPDAYDYNKAQVPGPLT 607
+R L DPT+++ + + + + F F +++ ++ Q+ L
Sbjct: 60 LRGALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLK 119
Query: 608 PEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRR----FAALSDREKRALAA- 662
+ E A +++E AA+RQ+E +QQRQ+EQ+ +E E++R L ++EK +A
Sbjct: 120 QQQEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAI 179
Query: 663 ---ERRLAAQ---LGAPTSPIP---DSAIVNTRRCWSC-GASLQGLTP 700
E +L Q L P P + ++ +CW ASL +P
Sbjct: 180 ASTEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSP 227
>gi|62750347 histone deacetylase 5 isoform 1 [Homo sapiens]
Length = 1122
Score = 44.3 bits (103), Expect = 4e-04
Identities = 42/168 (25%), Positives = 77/168 (45%), Gaps = 18/168 (10%)
Query: 551 VRLLLEAGADPTVQDSRARPPYTVAADKSTRNE---FRRFMEKNPDAYDYNKAQVPGPLT 607
+R L DPT+++ + + + + F F +++ ++ Q+ L
Sbjct: 59 LRGALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLK 118
Query: 608 PEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRR----FAALSDREKRALAA- 662
+ E A +++E AA+RQ+E +QQRQ+EQ+ +E E++R L ++EK +A
Sbjct: 119 QQQEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAI 178
Query: 663 ---ERRLAAQ---LGAPTSPIP---DSAIVNTRRCWSC-GASLQGLTP 700
E +L Q L P P + ++ +CW ASL +P
Sbjct: 179 ASTEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSP 226
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 43.9 bits (102), Expect = 5e-04
Identities = 60/264 (22%), Positives = 112/264 (42%), Gaps = 27/264 (10%)
Query: 452 AGAHRTLLQQTQEE-EPSTQSSQAVAAP-LGPLLDEAKAPGQPELWNALLAACRAGDVGV 509
AGA ++ +T E PS + + P + L+ + P + NA + +
Sbjct: 11 AGAPPAVVARTPPEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPES 70
Query: 510 LKLQLAPSPADPRVLSLLSAPLGSGGFTLLHAAAAAGRGSVVRLLLEAGADPTVQDSRAR 569
Q+ P PA P+ S ++ A RG + A P + S+
Sbjct: 71 PSGQVGPRPAPPQEES--------------PSSEAKSRGPTPPAMGPRDARPPRRSSQPS 116
Query: 570 PPYTVAADKS-TRNEFRRFMEKNPDAYDYNKAQVPGPLTPEMEARQAT--RKREQKAARR 626
P A+D T+ E ++ E++ A + + + + A++A K E+ A R
Sbjct: 117 PTAVPASDSPPTKQEVKKAGERHKLAKERREERAK-----YLAAKKAVWLEKEEKAKALR 171
Query: 627 QREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRLAAQLGAPTSPIPDSAIVNTR 686
+++ Q++R++ +E+R + EQRR AAL +R+++ L E+ A + + +
Sbjct: 172 EKQLQERRRRLEEQRLKAEQRR-AALEERQRQKL--EKNKERYEAAIQRSVKKTWAEIRQ 228
Query: 687 RCWSCGASLQGLTPFHYLDFSFCS 710
+ WS +L +P H S CS
Sbjct: 229 QRWSWAGALHHSSPGHKTSGSRCS 252
Score = 41.2 bits (95), Expect = 0.003
Identities = 54/247 (21%), Positives = 96/247 (38%), Gaps = 37/247 (14%)
Query: 434 PKRRRRKRNKKEKSRDQEAGAHRTLLQQTQEEEPSTQSSQAVAAPL-GPLLDEAKAPGQP 492
PK R R+ KE++++ + A Q++ + + S A A+P P AP Q
Sbjct: 504 PKGRVRR---KEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQK 560
Query: 493 ELWNALLAACRAGDVGVLKLQLAPSPADPRVLSLLSAPLGSGGFTLLHAAAAAGRGSVVR 552
E A D VL AP+P S P+ A R R
Sbjct: 561 EQPPAETPT----DAAVLTSPPAPAPPVTP-----SKPM----------AGTTDREEATR 601
Query: 553 LLLEAGADPTVQDSRARPPYTVAADKSTR-------NEFRRFMEKNPDAYDYNKAQVPGP 605
LL E Q R + A++ R E E+ +A + +
Sbjct: 602 LLAEKRRQAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREK 661
Query: 606 LTPEMEARQATRKREQKAARRQREEQQQRQ-------QEQEEREREEQRRFAALSDREKR 658
E E ++ +K++++A R REE ++++ Q+QE+ +E ++R + R ++
Sbjct: 662 AQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRK 721
Query: 659 ALAAERR 665
+ +E +
Sbjct: 722 SEVSETK 728
Score = 32.7 bits (73), Expect = 1.2
Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 8/66 (12%)
Query: 611 EARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRLAAQL 670
E R+ RR+ E +++E++++ERE +++EK ALA ER L +
Sbjct: 390 ERRKPNAGGSPAPVRRRPEASPVQKKEKKDKERE--------NEKEKSALARERSLKKRQ 441
Query: 671 GAPTSP 676
P SP
Sbjct: 442 SLPASP 447
>gi|225543463 tetratricopeptide repeat, ankyrin repeat and coiled-coil
containing 1 isoform 2 [Homo sapiens]
Length = 1390
Score = 43.5 bits (101), Expect = 7e-04
Identities = 41/121 (33%), Positives = 48/121 (39%), Gaps = 11/121 (9%)
Query: 459 LQQTQEEEPSTQSSQAVAAPLGPLLD-EAKAPGQPELWN--ALLAACRAGDVGVLKLQLA 515
LQQ S S V LG + E + G LW AL AA G + V +L L
Sbjct: 1033 LQQALTAAASMGHSSVVQCLLGMEKEHEVEVNGTDTLWGETALTAAAGRGKLEVCELLLG 1092
Query: 516 PSPADPRVLSLLSAPLGSGGFTLLHAAAAAGRGSVVRLLLEAGADPTVQDSRARPPYTVA 575
A R G L AA G +VRLLLE G D + D + R P VA
Sbjct: 1093 HGAAVSRT--------NRRGVPPLFCAARQGHWQIVRLLLERGCDVNLSDKQGRTPLMVA 1144
Query: 576 A 576
A
Sbjct: 1145 A 1145
>gi|225543461 tetratricopeptide repeat, ankyrin repeat and coiled-coil
containing 1 isoform 1 [Homo sapiens]
Length = 1861
Score = 43.5 bits (101), Expect = 7e-04
Identities = 41/121 (33%), Positives = 48/121 (39%), Gaps = 11/121 (9%)
Query: 459 LQQTQEEEPSTQSSQAVAAPLGPLLD-EAKAPGQPELWN--ALLAACRAGDVGVLKLQLA 515
LQQ S S V LG + E + G LW AL AA G + V +L L
Sbjct: 1041 LQQALTAAASMGHSSVVQCLLGMEKEHEVEVNGTDTLWGETALTAAAGRGKLEVCELLLG 1100
Query: 516 PSPADPRVLSLLSAPLGSGGFTLLHAAAAAGRGSVVRLLLEAGADPTVQDSRARPPYTVA 575
A R G L AA G +VRLLLE G D + D + R P VA
Sbjct: 1101 HGAAVSRT--------NRRGVPPLFCAARQGHWQIVRLLLERGCDVNLSDKQGRTPLMVA 1152
Query: 576 A 576
A
Sbjct: 1153 A 1153
>gi|239743649 PREDICTED: IQ motif and ankyrin repeat
domain-containing protein LOC642574 [Homo sapiens]
Length = 580
Score = 43.5 bits (101), Expect = 7e-04
Identities = 49/186 (26%), Positives = 75/186 (40%), Gaps = 18/186 (9%)
Query: 496 NALLAACRAGD-------VGVLKLQLAPSPADPRVLSLLSAPLGSGGFTLLHAAAAAGRG 548
+A C AGD +G +L+ DPR P G + + AA+ G
Sbjct: 6 SAFREGCPAGDSTPSSPFLGAPELRARRGSQDPRRRGAGEVPADLGPLRVPGSRAASSCG 65
Query: 549 SVVR--LLLEAGADPT--VQDSRARPPYTVAADKSTRNEFRRFMEKNPDAYDYNKAQVPG 604
R L AG + +D AR R E R E+ + + +
Sbjct: 66 LCGREPRLGRAGGFESRPAEDRAARAIQGAFRQLRARRELARRREERREYLEQME----- 120
Query: 605 PLTPEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAER 664
TP+ EA A +REQ+AARR RE+++ Q+E+ E + +R A D + + A
Sbjct: 121 --TPQKEAYLAPVRREQEAARRLREQEEAAQRERREELQRRRRLLDAAFDGDVGEIRAVL 178
Query: 665 RLAAQL 670
+ QL
Sbjct: 179 KEVEQL 184
Score = 43.5 bits (101), Expect = 7e-04
Identities = 61/244 (25%), Positives = 97/244 (39%), Gaps = 39/244 (15%)
Query: 438 RRKRNKKEKSRDQEAGAHRTLLQQTQEEEPSTQSS--------QAVAAPLGPLLDEAKAP 489
RR++ + R+QE A R ++ Q ++ +AV + LL +
Sbjct: 132 RREQEAARRLREQEEAAQRERREELQRRRRLLDAAFDGDVGEIRAVLKEVEQLLTR-EGV 190
Query: 490 GQPELWNA-------LLAACRAGDVGVLKLQLAPSPADPRVLSLLS----APLGSGGF-- 536
G E A LA C G L A + P + L + +P G F
Sbjct: 191 GHDEAGEARRLQRRVALAECE-DSYGNTPLSEAAAGGQPLAIQLRAELGASPNSKGAFGP 249
Query: 537 TLLHAAAAAGRGSVVRLLLEAGADPTVQDSRARPPYTVAADKSTRNEFRRFMEKNPDAYD 596
T L+ AA G + V +LL+ GADP V P VA+ + + R ++D
Sbjct: 250 TPLYRAAFGGHLAAVEVLLKLGADPRVYAEDGSTPERVASLDTVVSVLR--------SWD 301
Query: 597 YNKAQVPGPLTPEMEARQATRKRE-----QKAARRQREEQQQRQQEQEEREREEQRRFAA 651
+ + + MEA Q R +E + A R + QQ +EQ++ +E Q+ +
Sbjct: 302 LSLTEA---MLQNMEAEQQRRAQEAQRHKEAEAERMTLKVQQLTREQQQCHKELQQAYCE 358
Query: 652 LSDR 655
LS R
Sbjct: 359 LSRR 362
>gi|38176283 ankyrin repeat and SOCS box-containing protein 7
isoform 2 [Homo sapiens]
Length = 318
Score = 43.1 bits (100), Expect = 0.001
Identities = 32/80 (40%), Positives = 42/80 (52%), Gaps = 18/80 (22%)
Query: 492 PELWNALL--AACRAGDVGVLKLQL----APSPADPRVLSLLSAPLGSGGFTLLHAAAAA 545
PEL L AA AGDV ++ L +P+ D + G+TLLH +AA
Sbjct: 10 PELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRD------------ANGWTLLHFSAAR 57
Query: 546 GRGSVVRLLLEAGADPTVQD 565
G+ VR+ LE GADPTV+D
Sbjct: 58 GKERCVRVFLEHGADPTVKD 77
Score = 35.4 bits (80), Expect = 0.19
Identities = 32/120 (26%), Positives = 55/120 (45%), Gaps = 13/120 (10%)
Query: 460 QQTQEEEPSTQSSQAVAA----PLGPLLDEAKAPGQPEL--WNALLAACRAGDVGVLKLQ 513
++ E + Q AVAA + +L++ +P + W L + G +++
Sbjct: 7 RRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVF 66
Query: 514 LAPSPADPRVLSLLSAPLGSGGFTLLHAAAAAGRGSVVRLLLEAGADPTVQDSRARPPYT 573
L ADP V L+ GGFT LH AA GR + RL+LE+ + ++++ +T
Sbjct: 67 LEHG-ADPTVKDLI------GGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWT 119
Score = 31.2 bits (69), Expect = 3.5
Identities = 18/41 (43%), Positives = 22/41 (53%)
Query: 535 GFTLLHAAAAAGRGSVVRLLLEAGADPTVQDSRARPPYTVA 575
G+T LH AA GR S VRLLLE A+ + P +A
Sbjct: 117 GWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLA 157
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 43.1 bits (100), Expect = 0.001
Identities = 22/55 (40%), Positives = 36/55 (65%), Gaps = 4/55 (7%)
Query: 611 EARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERR 665
E R+ ++ EQ+ R +RE+Q +R+QE+E RE++E+RR +E+R ERR
Sbjct: 285 ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERR----EQQERREQQEERR 335
Score = 41.6 bits (96), Expect = 0.003
Identities = 26/75 (34%), Positives = 41/75 (54%), Gaps = 9/75 (12%)
Query: 597 YNKAQVPGPLTPEMEARQATRK------REQKAARRQREEQQQRQQEQEEREREEQRRFA 650
Y K L PE E +Q R+ RE++ R++REEQQ R QE + + REE++
Sbjct: 1746 YRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQ--- 1802
Query: 651 ALSDREKRALAAERR 665
+RE++ L ++R
Sbjct: 1803 LRQEREEQQLRPQQR 1817
Score = 41.2 bits (95), Expect = 0.003
Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 14/71 (19%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEERER--------------EEQRRFAALSD 654
E E R+ +REQ+ R Q E ++QR + QEE ER +E+RR L
Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKR 552
Query: 655 REKRALAAERR 665
E++ L ERR
Sbjct: 553 EEEKRLEQERR 563
Score = 40.4 bits (93), Expect = 0.006
Identities = 21/60 (35%), Positives = 37/60 (61%), Gaps = 2/60 (3%)
Query: 609 EMEARQATRKREQKAARRQREE--QQQRQQEQEEREREEQRRFAALSDREKRALAAERRL 666
+ E R+ +R ++ RR++EE +QQ ++EQEE RE+Q R +R ++ L E++L
Sbjct: 324 QQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQL 383
Score = 38.5 bits (88), Expect = 0.022
Identities = 19/54 (35%), Positives = 32/54 (59%)
Query: 611 EARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAER 664
E Q R+ +++A RR R+ Q+++Q +EERE + +R+ RE+ L ER
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQER 1348
Score = 38.5 bits (88), Expect = 0.022
Identities = 23/85 (27%), Positives = 47/85 (55%), Gaps = 8/85 (9%)
Query: 585 RRFMEKNPDAYDYNKAQVPGPLTPEMEARQATRKREQKAARRQREEQQQRQQEQEERERE 644
R+F+E+ P + Q ++ + + RE++ ++ EEQQ R+QE++ + RE
Sbjct: 1643 RKFLEEEPQLRRQEREQ-------QLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFRE 1695
Query: 645 EQRRFAALSDREKRALAAERRLAAQ 669
E+++ +RE++ L E++L Q
Sbjct: 1696 EEQQLRR-QERERKFLQEEQQLRRQ 1719
Score = 38.1 bits (87), Expect = 0.029
Identities = 22/59 (37%), Positives = 38/59 (64%), Gaps = 5/59 (8%)
Query: 611 EARQATRKREQKAARRQ---REEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRL 666
E R+ +REQ+ R Q RE++++R+++Q RE+EE+RR L R ++ L E++L
Sbjct: 333 ERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQL--RREQQLRREQQL 389
Score = 38.1 bits (87), Expect = 0.029
Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 9/71 (12%)
Query: 609 EMEARQATRKREQKAARRQR---------EEQQQRQQEQEEREREEQRRFAALSDREKRA 659
E E R+ KR+Q+ RR+R EQQ+R+++Q RE+EE+R E+
Sbjct: 468 EQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEER 527
Query: 660 LAAERRLAAQL 670
L R QL
Sbjct: 528 LQQRLRSEQQL 538
Score = 37.7 bits (86), Expect = 0.038
Identities = 76/352 (21%), Positives = 138/352 (39%), Gaps = 40/352 (11%)
Query: 329 RRPTFQELQRVLHKLTTLHVYEEDPREAVRLHSPQTHWKTVREERKKPTEEEIRKICRDE 388
R+ + LQ+ L L +E+ RE + + + R E++ E+E R+
Sbjct: 521 RQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERR----- 575
Query: 389 KEALGQNEESPKQGSGSEGEDGFQVELELVELTVGTLDLCESEVLPKRRRRKRNKKE--- 445
+ L + EE +Q E E+ + L+ E+ L + E +R +R+ ++E
Sbjct: 576 DQLLKREEERRQQRLKREQEERLEQRLKREEVE----RLEQEERREQRLKREEPEEERRQ 631
Query: 446 ---KSRDQEAGAHRTLLQQTQEEEPSTQSSQAVAAPLGPLL--DEAKAPGQPELWNALLA 500
KS +QE + L ++ QE + L L + + + EL
Sbjct: 632 QLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQE 691
Query: 501 ACRA---GDVGVLKLQLAPSPADPRVLSLLSAPLGSGGFTLLHAAAAAGRG--SVVRLLL 555
R + + QL S AD R + S P G R S ++
Sbjct: 692 QARERIKSRIPKWQWQLE-SEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQE 750
Query: 556 EAGADPTVQDSRARPPYT---VAADKSTRNEFRRFMEKNPDAYDYNKAQVPGPLTPEMEA 612
E A Q+ R +T A +KS R R+ + P PL + E
Sbjct: 751 EERAHRQQQEEEQRRDFTWQWQAEEKSERG--RQRLSARP------------PLREQRER 796
Query: 613 RQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAER 664
+ +R+Q+ R EE+++ Q+ ++ RERE++ +F ++ +R A++
Sbjct: 797 QLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQ 848
Score = 37.4 bits (85), Expect = 0.050
Identities = 20/80 (25%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Query: 578 KSTRNEFRRFMEKNPDAYDYNKAQVPGPLTPEMEARQATRKREQKAARRQREEQQQRQQE 637
K R E RR E+ + + + L + E + ++ E++ + +RE+Q++R+++
Sbjct: 280 KLERQELRR--ERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQ 337
Query: 638 QEEREREEQRRFAALSDREK 657
Q RE+EE+R ++E+
Sbjct: 338 QLRREQEERREQQLRREQEE 357
Score = 37.4 bits (85), Expect = 0.050
Identities = 27/70 (38%), Positives = 40/70 (57%), Gaps = 8/70 (11%)
Query: 608 PEMEARQATRKREQKAARRQ----REEQQQRQQE---QEEREREEQR-RFAALSDREKRA 659
PE E RQ K E++ RRQ RE+Q++R+Q +EE ER EQR + +R ++
Sbjct: 625 PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQE 684
Query: 660 LAAERRLAAQ 669
LA E + A+
Sbjct: 685 LAEEEQEQAR 694
Score = 37.4 bits (85), Expect = 0.050
Identities = 85/383 (22%), Positives = 149/383 (38%), Gaps = 79/383 (20%)
Query: 314 LQRGDPRLWDIPLATRRPTFQELQRVLHKLTTLHVYEE-----DPREAVRLHSP------ 362
LQ+ + +L TRR QEL+R K L EE +P + R
Sbjct: 1056 LQQEEEQLLGEERETRRR--QELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREE 1113
Query: 363 ----QTHWKTVREERKKPTEEEIRKICRDEKEALGQNE----ESPKQGSGSEGEDGFQVE 414
Q + +REER+K +E+ + R+E+E + E E P++ E E ++ E
Sbjct: 1114 EELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREE 1173
Query: 415 LELVELTVGTLDLCESEVLPKRRRRKRNKKEKSRDQEAGAHRTLLQQTQEEEPSTQSSQA 474
EL + E E L R ++ K+ + R+++ L +Q +++ + ++
Sbjct: 1174 EELQQ---------EEEQL---LREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRS 1221
Query: 475 VAAPLGPLLDEAKAPGQPELWNALL---AACRAGDVGVLKLQLAPSPADPRVLSLLSAPL 531
+ K +PE NA+ C+ + + QL S R
Sbjct: 1222 ----------DLKWQWEPEKENAVRDNKVYCKGRENEQFR-QLEDSQLRDR--------- 1261
Query: 532 GSGGFTLLHAAAAAGRGSVVRLLLEAGADPTVQDSRA---RPPYTVAADKSTRNEFRRFM 588
+ + LL E Q+ R R + ++ R E +
Sbjct: 1262 -------------QSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKE-- 1306
Query: 589 EKNPDAYDYNKAQVPGPLTPEMEARQATRK--REQKAARRQREEQQQRQQEQEEREREEQ 646
K D + Q+ E RQ T + RE++ ++REEQ R+QE++ + REE+
Sbjct: 1307 AKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEE 1366
Query: 647 RRFAALSDREKRALAAERRLAAQ 669
R ++ ++ L E+RL Q
Sbjct: 1367 LRH---QEQGRKFLEEEQRLRRQ 1386
Score = 36.6 bits (83), Expect = 0.084
Identities = 22/60 (36%), Positives = 36/60 (60%), Gaps = 10/60 (16%)
Query: 611 EARQATRKREQKAARRQREEQQQRQQE-----QEEREREEQRRFAALSDREKRALAAERR 665
E +Q R R ++ RR++EE+++ QQE QE RE++E+RR +++ R ERR
Sbjct: 293 EEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERR-----EQQLRREQEERR 347
Score = 36.2 bits (82), Expect = 0.11
Identities = 22/56 (39%), Positives = 34/56 (60%), Gaps = 4/56 (7%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAER 664
E E +Q +REQ+ R+Q EE R+++QEER RE+Q R +R ++ L E+
Sbjct: 292 EEEQQQQRLRREQQLRRKQEEE---RREQQEER-REQQERREQQEERREQQLRREQ 343
Score = 36.2 bits (82), Expect = 0.11
Identities = 19/62 (30%), Positives = 36/62 (58%), Gaps = 2/62 (3%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRLAA 668
++ +Q +REQ+ RR E+Q++R+Q++E RE++ +R +++ R E R
Sbjct: 305 QLRRKQEEERREQQEERR--EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQ 362
Query: 669 QL 670
QL
Sbjct: 363 QL 364
Score = 35.4 bits (80), Expect = 0.19
Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 6/86 (6%)
Query: 606 LTPEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQ-----RRFAALSDREKRAL 660
L E R+ +++EQ+ + EEQ ++Q+ E+R+R+ + R+ +RE+R
Sbjct: 129 LEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERR- 187
Query: 661 AAERRLAAQLGAPTSPIPDSAIVNTR 686
A E +L + G T PD + R
Sbjct: 188 AEEEQLQSCKGHETEEFPDEEQLRRR 213
Score = 35.4 bits (80), Expect = 0.19
Identities = 19/52 (36%), Positives = 28/52 (53%)
Query: 613 RQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAER 664
R+ +REQ+ R Q EE+ +++ EQE RE+ +R D KR ER
Sbjct: 415 REQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETER 466
Score = 35.4 bits (80), Expect = 0.19
Identities = 19/62 (30%), Positives = 38/62 (61%), Gaps = 3/62 (4%)
Query: 607 TPEMEARQATRKR---EQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAE 663
T + + R+ R R E++ R +REEQQ R+QE++ + REE++ +++ R+ ++
Sbjct: 1735 TEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESD 1794
Query: 664 RR 665
R+
Sbjct: 1795 RK 1796
Score = 35.0 bits (79), Expect = 0.25
Identities = 21/57 (36%), Positives = 34/57 (59%), Gaps = 5/57 (8%)
Query: 613 RQATRKREQKAARRQREE---QQQRQQEQEEREREEQRRFAALSDREKRALAAERRL 666
R+ +REQ+ R Q EE QQ R++++EER ++ RR L R ++ L E++L
Sbjct: 341 REQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQL--RREQQLRREQQL 395
Score = 35.0 bits (79), Expect = 0.25
Identities = 25/65 (38%), Positives = 39/65 (60%), Gaps = 8/65 (12%)
Query: 609 EMEARQATRKREQKAARR--QREEQ-----QQRQQEQEEREREEQRRFAALS-DREKRAL 660
E E R+ KREQ+ R +REE+ Q+R+++Q +R++EE+RR L + E+R
Sbjct: 439 EQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERRE 498
Query: 661 AAERR 665
ERR
Sbjct: 499 QQERR 503
Score = 35.0 bits (79), Expect = 0.25
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 4/61 (6%)
Query: 608 PEMEARQATRKREQKAARRQREEQQQRQQEQEEREREE----QRRFAALSDREKRALAAE 663
PE RQ K+ ++ Q+EE+Q ++E+E+R R+E R+ L E++ L E
Sbjct: 978 PEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREE 1037
Query: 664 R 664
R
Sbjct: 1038 R 1038
Score = 34.7 bits (78), Expect = 0.32
Identities = 17/58 (29%), Positives = 33/58 (56%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRL 666
++ Q +REQ+ R Q EE++++Q +E++ R EQ+ R ++ L E++L
Sbjct: 350 QLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 407
Score = 34.7 bits (78), Expect = 0.32
Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 9/67 (13%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQ----QEQEER-----EREEQRRFAALSDREKRA 659
E+E + +REQ+ R + EE++++Q +EQEER RE+Q R RE+
Sbjct: 606 EVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEE 665
Query: 660 LAAERRL 666
E+RL
Sbjct: 666 ERLEQRL 672
Score = 34.3 bits (77), Expect = 0.42
Identities = 31/112 (27%), Positives = 50/112 (44%), Gaps = 12/112 (10%)
Query: 354 REAVRLHSPQTHWKTVREERKKPTEEEIRKICRDEKEALGQNEESPKQGSGSEGEDGFQV 413
RE Q H + RE+R K +EE R + E+E +E KQ + E+
Sbjct: 427 REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEE---- 482
Query: 414 ELELVELTVGTLDLCESEVLPKRRRRKRNKKEKSRDQEAGAHRTLLQQTQEE 465
E L L E E +R +++R +++ R+QE + L +Q +EE
Sbjct: 483 -----ERRERWLKLEEEE---RREQQERREQQLRREQEERREQRLKRQEEEE 526
Score = 34.3 bits (77), Expect = 0.42
Identities = 20/61 (32%), Positives = 31/61 (50%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRLAA 668
E R +R+Q+ R Q EE+++R + EE ER EQ+ R ++ E+RL
Sbjct: 462 EETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKR 521
Query: 669 Q 669
Q
Sbjct: 522 Q 522
Score = 34.3 bits (77), Expect = 0.42
Identities = 19/50 (38%), Positives = 31/50 (62%), Gaps = 2/50 (4%)
Query: 619 REQKAARRQREEQQQRQQE--QEEREREEQRRFAALSDREKRALAAERRL 666
REQ+ + + EE+QQR+Q EE E+E++RR ++E + L E +L
Sbjct: 791 REQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQL 840
Score = 34.3 bits (77), Expect = 0.42
Identities = 15/42 (35%), Positives = 29/42 (69%), Gaps = 2/42 (4%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQE--EREREEQRR 648
E++ + ++R Q+ R+ REE+Q +Q+E++ ERE++RR
Sbjct: 912 ELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRR 953
Score = 34.3 bits (77), Expect = 0.42
Identities = 17/49 (34%), Positives = 30/49 (61%)
Query: 610 MEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKR 658
++ Q R++E+ RRQ +++ R++EQ +EREEQ+ DR+ R
Sbjct: 1534 LQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFR 1582
Score = 34.3 bits (77), Expect = 0.42
Identities = 17/53 (32%), Positives = 35/53 (66%), Gaps = 1/53 (1%)
Query: 619 REQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRLAAQLG 671
RE++ R++REEQQ +QE++ + R E+++ ++E++ + E++L Q G
Sbjct: 1558 REEEQLRQEREEQQLSRQERDRKFRLEEQK-VRRQEQERKFMEDEQQLRRQEG 1609
Score = 34.3 bits (77), Expect = 0.42
Identities = 17/51 (33%), Positives = 30/51 (58%)
Query: 619 REQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRLAAQ 669
R Q+ R+ REE+Q RQ+ ++E+ R ++R L + + R E++L Q
Sbjct: 1717 RRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQ 1767
Score = 33.9 bits (76), Expect = 0.55
Identities = 17/62 (27%), Positives = 30/62 (48%)
Query: 597 YNKAQVPGPLTPEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDRE 656
Y K + L E + Q + Q+ R +R Q+Q +Q +EE + +++ +RE
Sbjct: 890 YAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE 949
Query: 657 KR 658
KR
Sbjct: 950 KR 951
Score = 33.5 bits (75), Expect = 0.71
Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
Query: 610 MEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRLAAQ 669
ME Q R++E + RQ +++ R+ EQ +EREEQ+ +R+++ L E +L Q
Sbjct: 1598 MEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHR--QERDRKFLEEEPQLRRQ 1655
Score = 33.5 bits (75), Expect = 0.71
Identities = 17/51 (33%), Positives = 36/51 (70%), Gaps = 2/51 (3%)
Query: 609 EMEARQATRK-REQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKR 658
++ ++++ RK RE++ R++REEQQ R Q+++ + R E+ + L ++E+R
Sbjct: 1787 QLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQL-QLEEQEQR 1836
Score = 33.1 bits (74), Expect = 0.93
Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 7/74 (9%)
Query: 604 GPLTPEMEARQATRKREQKAARRQ-REEQQQRQQE------QEEREREEQRRFAALSDRE 656
G T E + R+RE RR+ REE+QQ+++E QEE E+E ++R L E
Sbjct: 198 GHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEE 257
Query: 657 KRALAAERRLAAQL 670
++ E + +L
Sbjct: 258 EKLQEEEPQRQREL 271
Score = 33.1 bits (74), Expect = 0.93
Identities = 17/58 (29%), Positives = 35/58 (60%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRL 666
E E R+ +REQ+ RR+++ ++++Q +E++ R EQ+ R ++ L E++L
Sbjct: 356 EEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 413
Score = 33.1 bits (74), Expect = 0.93
Identities = 19/58 (32%), Positives = 34/58 (58%), Gaps = 6/58 (10%)
Query: 611 EARQATRKREQKAARRQREEQQQRQQEQEERE----REEQRRFAALSDREKRALAAER 664
E R ++ E++ +R R EQQ R++++E RE REE++R +R ++ L E+
Sbjct: 516 EQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLE--QERREQRLKREQ 571
Score = 33.1 bits (74), Expect = 0.93
Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEERE----REEQRRFAALSDREKRALAAER 664
E Q ++ E+K ++R EQ+ +++++E R+ REE+RR L ++ L E+
Sbjct: 543 EERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERL--EQ 600
Query: 665 RL 666
RL
Sbjct: 601 RL 602
Score = 33.1 bits (74), Expect = 0.93
Identities = 33/106 (31%), Positives = 53/106 (50%), Gaps = 14/106 (13%)
Query: 363 QTHWKTVREERKKPTEEEIRKICRDEKEALGQNEESPKQGSGSEGEDGFQVELELVELTV 422
Q + +REER+K +E + R+E+E L Q EE Q G E E + ELE
Sbjct: 1028 QEEEQLLREEREKRRLQERERQYREEEE-LQQEEE---QLLGEERETRRRQELERQYRKE 1083
Query: 423 GTLDLCESEVL---PKRRRRKRNKKEKSRDQEAGAHRTLLQQTQEE 465
L E ++L P++RRR+ +++ ++E LQQ +E+
Sbjct: 1084 EELQQEEEQLLREEPEKRRRQERERQCREEEE-------LQQEEEQ 1122
Score = 33.1 bits (74), Expect = 0.93
Identities = 14/58 (24%), Positives = 34/58 (58%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRL 666
++ ++ ++ Q R+ REE+QQ +++ +R+ E+ + +RE++ L E++L
Sbjct: 1398 QLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQL 1455
Score = 33.1 bits (74), Expect = 0.93
Identities = 16/55 (29%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Query: 611 EARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERR 665
E Q ++ E++ RRQ +++ R++EQ+ R +E +R+F +++ R ER+
Sbjct: 1671 EEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQ-EEQQLRRQELERK 1724
Score = 32.7 bits (73), Expect = 1.2
Identities = 20/59 (33%), Positives = 35/59 (59%), Gaps = 5/59 (8%)
Query: 611 EARQATRKREQKAARRQ---REEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRL 666
E R+ +REQ+ RR+ R EQ++ ++EQ+ R ++ RR L R ++ L E++L
Sbjct: 345 ERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL--RREQQLRREQQL 401
Score = 32.7 bits (73), Expect = 1.2
Identities = 21/86 (24%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Query: 581 RNEFRRFMEKNPDAYDYNKAQVPGPLTPEMEARQATRKREQKAARRQREEQQQRQQEQEE 640
R+ +R E + K Q+ E R + E++ +++R EQQ R++++E
Sbjct: 455 RDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEER 514
Query: 641 REREEQRRFAALSDREKRALAAERRL 666
RE+ +R+ +R ++ L +E++L
Sbjct: 515 REQRLKRQ--EEEERLQQRLRSEQQL 538
Score = 32.7 bits (73), Expect = 1.2
Identities = 16/60 (26%), Positives = 34/60 (56%)
Query: 606 LTPEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERR 665
L E E R R + ++ R ++EE+++++ ++EE E E +++ ++E+R RR
Sbjct: 590 LKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRR 649
Score = 32.3 bits (72), Expect = 1.6
Identities = 17/67 (25%), Positives = 38/67 (56%), Gaps = 2/67 (2%)
Query: 606 LTPEMEARQATRKREQKAARRQREE--QQQRQQEQEEREREEQRRFAALSDREKRALAAE 663
L E + R+ +R ++ +R+ E+ +Q+R++++ +RE+EE+R + E+R +
Sbjct: 532 LRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK 591
Query: 664 RRLAAQL 670
R +L
Sbjct: 592 REQEERL 598
Score = 32.3 bits (72), Expect = 1.6
Identities = 32/136 (23%), Positives = 62/136 (45%), Gaps = 9/136 (6%)
Query: 334 QELQRVLHKLTTLHVYEEDPREAVRLHSPQTHWKTVREERKKPTEEEIRKICRDEKEALG 393
+E +R H L +E R+ +L + + REER+K +E + R+E++
Sbjct: 880 EERKRRRHTLYAKPALQEQLRKEQQLLQEEEE-ELQREEREKRRRQEQERQYREEEQLQQ 938
Query: 394 QNE----ESPKQGSGSEGEDGFQVELELVELTVGTLDLCESEVLPKRRRRKRNKKEKSRD 449
+ E E ++ E E ++ + +L + L E KRRR++R KK + +
Sbjct: 939 EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLL----GEEPEKRRRQEREKKYREEE 994
Query: 450 QEAGAHRTLLQQTQEE 465
+ LL++ +E+
Sbjct: 995 ELQQEEEQLLREEREK 1010
Score = 32.3 bits (72), Expect = 1.6
Identities = 19/54 (35%), Positives = 33/54 (61%), Gaps = 8/54 (14%)
Query: 617 RKREQKAARRQRE-----EQQQRQQEQEEREREEQRRFAALSDREKRALAAERR 665
R+ EQ+ R++RE E+QQ +QE+ + REE++ L +RE++ L + R
Sbjct: 1433 REEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQ---LLQEREEQQLHRQER 1483
Score = 32.3 bits (72), Expect = 1.6
Identities = 19/82 (23%), Positives = 44/82 (53%), Gaps = 1/82 (1%)
Query: 585 RRFMEKNPDAYDYNKAQVPGPLTPEMEARQATRKREQKAARRQREEQQQR-QQEQEERER 643
R+F+E+ + + + ++ ++ ++R Q R+ REE+Q R ++E+++ R
Sbjct: 1515 RKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSR 1574
Query: 644 EEQRRFAALSDREKRALAAERR 665
+E+ R L +++ R ER+
Sbjct: 1575 QERDRKFRLEEQKVRRQEQERK 1596
Score = 32.3 bits (72), Expect = 1.6
Identities = 13/39 (33%), Positives = 26/39 (66%)
Query: 611 EARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRF 649
E Q ++RE++ RQ +++ R +EQ+ R +E++R+F
Sbjct: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKF 1597
Score = 32.3 bits (72), Expect = 1.6
Identities = 17/56 (30%), Positives = 32/56 (57%), Gaps = 4/56 (7%)
Query: 614 QATRKREQKAARRQREEQQQRQQEQEEREREEQRRF----AALSDREKRALAAERR 665
Q R++EQ+ + E+Q +RQ+ Q++ +E R+F L +RE++ L + R
Sbjct: 1586 QKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQER 1641
Score = 32.0 bits (71), Expect = 2.1
Identities = 16/62 (25%), Positives = 36/62 (58%), Gaps = 4/62 (6%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEER----EREEQRRFAALSDREKRALAAER 664
E R+ ++E++ + + ++Q+ QE+EE+ ER+E RR +++++ L E+
Sbjct: 245 EWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQ 304
Query: 665 RL 666
+L
Sbjct: 305 QL 306
Score = 32.0 bits (71), Expect = 2.1
Identities = 22/59 (37%), Positives = 32/59 (54%), Gaps = 6/59 (10%)
Query: 613 RQATRKREQKAARRQ--REEQQQRQQEQEERE----REEQRRFAALSDREKRALAAERR 665
R+ +REQ+ R Q R EQQ R+++Q RE RE+Q R +R ++ ERR
Sbjct: 385 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERR 443
Score = 32.0 bits (71), Expect = 2.1
Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 8/66 (12%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQ--------EEREREEQRRFAALSDREKRAL 660
++ Q + EQK + +RE++ +R+QE+ EE ER EQ R R++
Sbjct: 424 QLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEE 483
Query: 661 AAERRL 666
ER L
Sbjct: 484 RRERWL 489
Score = 32.0 bits (71), Expect = 2.1
Identities = 20/64 (31%), Positives = 37/64 (57%), Gaps = 5/64 (7%)
Query: 609 EMEARQATRKR---EQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERR 665
E + R+ R+R E++ RQ ++ R++EQ +EREEQ+ +R+++ L E++
Sbjct: 1436 EQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHR--QERDRKFLEEEQQ 1493
Query: 666 LAAQ 669
L Q
Sbjct: 1494 LRRQ 1497
Score = 32.0 bits (71), Expect = 2.1
Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 8/68 (11%)
Query: 606 LTPEMEARQATRK--REQKAARRQREEQQQRQQE------QEEREREEQRRFAALSDREK 657
L E + RQ + RE++ ++REEQQ +QE +EE++ Q R ++E
Sbjct: 1449 LEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQEL 1508
Query: 658 RALAAERR 665
R+ ER+
Sbjct: 1509 RSQEPERK 1516
Score = 32.0 bits (71), Expect = 2.1
Identities = 13/32 (40%), Positives = 23/32 (71%)
Query: 613 RQATRKREQKAARRQREEQQQRQQEQEERERE 644
++ +KR Q+ R+ REE +RQQ++E+R R+
Sbjct: 1866 QEEEQKRRQERERKLREEHIRRQQKEEQRHRQ 1897
Score = 31.6 bits (70), Expect = 2.7
Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
Query: 609 EMEARQATRKREQKAARRQ--REEQQQRQQEQEEREREEQRRFAALSDREKRALAAERR 665
E E R+ +REQ+ R Q R EQQ R+++Q RE++ +R +++ R RR
Sbjct: 369 EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 427
Score = 31.6 bits (70), Expect = 2.7
Identities = 14/56 (25%), Positives = 29/56 (51%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAER 664
++ Q R+ +Q +Q +QQ ++EQ+ R +E+ R ++E+R +R
Sbjct: 394 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR 449
Score = 31.6 bits (70), Expect = 2.7
Identities = 14/54 (25%), Positives = 36/54 (66%), Gaps = 1/54 (1%)
Query: 606 LTPEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALS-DREKR 658
L E + R+ + R ++ RR+++ ++++++E+ E++ E++RR L ++E+R
Sbjct: 401 LRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEER 454
Score = 31.6 bits (70), Expect = 2.7
Identities = 15/53 (28%), Positives = 29/53 (54%)
Query: 613 RQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERR 665
R+ +REQ+ R Q+ ++Q+ + ++E ER EQ+ ++ + ERR
Sbjct: 403 REQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERR 455
Score = 31.6 bits (70), Expect = 2.7
Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 7/67 (10%)
Query: 606 LTPEMEARQATRKREQKAARRQREEQQQRQQEQEER-----EREEQRRFAALSDRE--KR 658
L E E R +REQ+ R Q E + Q + +EER +RE++ R RE +R
Sbjct: 550 LKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVER 609
Query: 659 ALAAERR 665
ERR
Sbjct: 610 LEQEERR 616
Score = 31.6 bits (70), Expect = 2.7
Identities = 16/62 (25%), Positives = 33/62 (53%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRLAA 668
E++ + RE++ RR +E ++Q ++E+E ++ EEQ R ++ L + R
Sbjct: 1025 ELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEE 1084
Query: 669 QL 670
+L
Sbjct: 1085 EL 1086
Score = 31.2 bits (69), Expect = 3.5
Identities = 37/153 (24%), Positives = 56/153 (36%), Gaps = 23/153 (15%)
Query: 330 RPTFQELQRVLHKLTTLHVYEEDPREAVRLHSPQTHWKTVREERKKPTEEEIRKICR--- 386
RP QE QR ++ E R + W+ ++ EEE R+
Sbjct: 722 RPRKQEGQR----------RRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQW 771
Query: 387 --DEKEALGQNEESPKQGSGSEGEDGFQVELELVELTVGTLDLCESEVLPKRRRRKRNKK 444
+EK G+ S + + E + E E E ++RRR+R ++
Sbjct: 772 QAEEKSERGRQRLSARPPLREQRERQLRAE----ERQQREQRFLPEEEEKEQRRRQRRER 827
Query: 445 EKS----RDQEAGAHRTLLQQTQEEEPSTQSSQ 473
EK ++E R QQ QEEE Q Q
Sbjct: 828 EKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQ 860
Score = 31.2 bits (69), Expect = 3.5
Identities = 22/64 (34%), Positives = 34/64 (53%), Gaps = 8/64 (12%)
Query: 618 KREQKAARRQREEQQQRQ-----QEQEEREREEQRRFAA---LSDREKRALAAERRLAAQ 669
+ E++A R+Q+EE+Q+R Q +E+ ER QR A RE++ A ER+ Q
Sbjct: 749 QEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQ 808
Query: 670 LGAP 673
P
Sbjct: 809 RFLP 812
Score = 31.2 bits (69), Expect = 3.5
Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 3/60 (5%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEER---EREEQRRFAALSDREKRALAAERR 665
E RQ ++ +K Q+EE+Q ++E+E+R ERE Q R +E+ L E R
Sbjct: 1009 EKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEER 1068
Score = 31.2 bits (69), Expect = 3.5
Identities = 16/62 (25%), Positives = 34/62 (54%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRLAA 668
E++ + RE++ RR++E ++Q ++E+E ++ EEQ R ++ L + R
Sbjct: 1115 ELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEE 1174
Query: 669 QL 670
+L
Sbjct: 1175 EL 1176
Score = 30.8 bits (68), Expect = 4.6
Identities = 37/137 (27%), Positives = 57/137 (41%), Gaps = 21/137 (15%)
Query: 334 QELQRVLHKLTTLHVYEEDPREAVRLHSPQTHWKTVREERKKPTEEEIRKICRDEKEALG 393
+ELQR + E RE +L Q + +REER+K +E + R +K+
Sbjct: 911 EELQREEREKRRRQEQERQYREEEQLQ--QEEEQLLREEREKRRRQERERQYRKDKKLQQ 968
Query: 394 QNE----ESPKQGSGSEGEDGFQVELELVELTVGTLDLCESEVLPKRRRRKRNKKEKSRD 449
+ E E P++ E E ++ E EL + E E L R ++EK R
Sbjct: 969 KEEQLLGEEPEKRRRQEREKKYREEEELQQ---------EEEQL------LREEREKRRR 1013
Query: 450 QEAGAHRTLLQQTQEEE 466
QE + Q+EE
Sbjct: 1014 QEWERQYRKKDELQQEE 1030
Score = 30.8 bits (68), Expect = 4.6
Identities = 38/142 (26%), Positives = 65/142 (45%), Gaps = 11/142 (7%)
Query: 337 QRVLHKLTTLHVYEEDPREAVRL-HSPQTHWKTVREERK-KPTEEEIRKICRDEKEALGQ 394
QR H + E+ +EA R Q + +REER+ K +E + R+E++ L +
Sbjct: 1288 QRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQE 1347
Query: 395 NEESPKQGSGSEGEDGFQVELELVELTVGTLDLCESEVLPKRRRRKRNKKE------KSR 448
EE P + E + F+ E EL G L E + L ++ R ++ KE + R
Sbjct: 1348 REEQPLR--RQERDRKFREE-ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQER 1404
Query: 449 DQEAGAHRTLLQQTQEEEPSTQ 470
+Q+ R + +E++ S Q
Sbjct: 1405 EQQLRQDRDRKFREEEQQLSRQ 1426
Score = 30.8 bits (68), Expect = 4.6
Identities = 17/59 (28%), Positives = 33/59 (55%), Gaps = 3/59 (5%)
Query: 611 EARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRLAAQ 669
E Q ++RE++ R Q+ + + R +E++ + E+++R DR+ R AE + A Q
Sbjct: 1799 EEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYR---AEEQFATQ 1854
Score = 30.4 bits (67), Expect = 6.1
Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 5/63 (7%)
Query: 609 EMEARQATRKREQKAARRQ--REEQQQRQQEQEERE---REEQRRFAALSDREKRALAAE 663
++ Q +REQ+ R Q R EQQ R+++Q RE R EQ+ R ++ L E
Sbjct: 363 QLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 422
Query: 664 RRL 666
++L
Sbjct: 423 QQL 425
Score = 30.4 bits (67), Expect = 6.1
Identities = 32/118 (27%), Positives = 56/118 (47%), Gaps = 8/118 (6%)
Query: 355 EAVRLHSPQTHWKTVREERKKPTEE--EIRKICRD----EKEALGQNEESPKQGSGSEGE 408
E +LH Q K ++EE++ +E + R+ RD E+E L Q E +Q S E +
Sbjct: 1520 EEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREE-QQLSRQERD 1578
Query: 409 DGFQVELELVELTVGTLDLCESEVLPKRRRRKRNKKEKSRDQEAGAHRTLLQQTQEEE 466
F++E + V E E RR+ + + + RD++ LLQ+ +E++
Sbjct: 1579 RKFRLEEQKVRRQEQERKFMEDEQ-QLRRQEGQQQLRQERDRKFREDEQLLQEREEQQ 1635
Score = 30.4 bits (67), Expect = 6.1
Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 9/59 (15%)
Query: 609 EMEARQATRKR----EQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAE 663
E + R+ R R E++ RRQ E++ Q+EQ+ R +E +R+F RE+ L E
Sbjct: 1681 EQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKF-----REEEQLRQE 1734
Score = 30.0 bits (66), Expect = 7.9
Identities = 16/53 (30%), Positives = 32/53 (60%), Gaps = 4/53 (7%)
Query: 617 RKREQKAARRQ----REEQQQRQQEQEEREREEQRRFAALSDREKRALAAERR 665
++ E+K R++ R+E+++ Q+E+ +R+RE Q L E++ L ER+
Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQ 291
Score = 30.0 bits (66), Expect = 7.9
Identities = 28/109 (25%), Positives = 46/109 (42%), Gaps = 8/109 (7%)
Query: 370 REERKKPTEEEIRKICRDEKEALGQNEESPKQGSGSEGEDGFQVELELVELTVGTLDLCE 429
R+ + EE++RK+ R E Q EE +Q E + + E E E + E
Sbjct: 267 RQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQE 326
Query: 430 SEVLPKRRRRKRNKKEKS--------RDQEAGAHRTLLQQTQEEEPSTQ 470
+ RR ++ ++E+ R+QE L++ QEEE Q
Sbjct: 327 RREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQ 375
Score = 30.0 bits (66), Expect = 7.9
Identities = 14/54 (25%), Positives = 33/54 (61%), Gaps = 3/54 (5%)
Query: 611 EARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAER 664
+ R+ + +++ QREE+++R+++++ER+ E+ + L E++ L ER
Sbjct: 898 QLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQ---LQQEEEQLLREER 948
Score = 30.0 bits (66), Expect = 7.9
Identities = 13/38 (34%), Positives = 24/38 (63%)
Query: 611 EARQATRKREQKAARRQREEQQQRQQEQEEREREEQRR 648
E + R++E++ R+ EE QQ +++ ERE++RR
Sbjct: 976 EEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR 1013
Score = 30.0 bits (66), Expect = 7.9
Identities = 16/50 (32%), Positives = 29/50 (58%), Gaps = 1/50 (2%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKR 658
E R+ KR ++ RQ ++ + QQE+E+ REE+ + L +RE++
Sbjct: 1001 EQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREK-RRLQERERQ 1049
Score = 30.0 bits (66), Expect = 7.9
Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 8/65 (12%)
Query: 609 EMEARQATRK--REQKAARRQREEQQQRQQEQEER--EREEQRRFAALSDREKRALAAER 664
E+ ++ RK E++ RRQ E++ ++EQ+ R ERE+Q R DR+++ E+
Sbjct: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLR----QDRDRKFREEEQ 1421
Query: 665 RLAAQ 669
+L+ Q
Sbjct: 1422 QLSRQ 1426
Score = 30.0 bits (66), Expect = 7.9
Identities = 18/60 (30%), Positives = 32/60 (53%), Gaps = 7/60 (11%)
Query: 606 LTPEMEARQATRKR-------EQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKR 658
L E E +Q +R+ E++ RRQ +E++ + EQ+ R +E Q++ DR+ R
Sbjct: 1563 LRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFR 1622
>gi|30089994 ankyrin repeat and SOCS box-containing protein 7
isoform 1 [Homo sapiens]
Length = 274
Score = 43.1 bits (100), Expect = 0.001
Identities = 32/80 (40%), Positives = 42/80 (52%), Gaps = 18/80 (22%)
Query: 492 PELWNALL--AACRAGDVGVLKLQL----APSPADPRVLSLLSAPLGSGGFTLLHAAAAA 545
PEL L AA AGDV ++ L +P+ D + G+TLLH +AA
Sbjct: 10 PELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRD------------ANGWTLLHFSAAR 57
Query: 546 GRGSVVRLLLEAGADPTVQD 565
G+ VR+ LE GADPTV+D
Sbjct: 58 GKERCVRVFLEHGADPTVKD 77
Score = 35.4 bits (80), Expect = 0.19
Identities = 32/120 (26%), Positives = 55/120 (45%), Gaps = 13/120 (10%)
Query: 460 QQTQEEEPSTQSSQAVAA----PLGPLLDEAKAPGQPEL--WNALLAACRAGDVGVLKLQ 513
++ E + Q AVAA + +L++ +P + W L + G +++
Sbjct: 7 RRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVF 66
Query: 514 LAPSPADPRVLSLLSAPLGSGGFTLLHAAAAAGRGSVVRLLLEAGADPTVQDSRARPPYT 573
L ADP V L+ GGFT LH AA GR + RL+LE+ + ++++ +T
Sbjct: 67 LEHG-ADPTVKDLI------GGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWT 119
Score = 31.2 bits (69), Expect = 3.5
Identities = 18/41 (43%), Positives = 22/41 (53%)
Query: 535 GFTLLHAAAAAGRGSVVRLLLEAGADPTVQDSRARPPYTVA 575
G+T LH AA GR S VRLLLE A+ + P +A
Sbjct: 117 GWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLA 157
>gi|55742857 ankyrin repeat domain 6 [Homo sapiens]
Length = 722
Score = 43.1 bits (100), Expect = 0.001
Identities = 40/155 (25%), Positives = 64/155 (41%), Gaps = 19/155 (12%)
Query: 535 GFTLLHAAAAAGRGSVVRLLLEAGADPTVQDSRARPPYTVAADKSTRNEFRRFMEKNPDA 594
G T LH AAA V ++LLEAGAD T+ ++ + P A E + K P
Sbjct: 207 GDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETAR-YHNNPEVALLLTKAPQV 265
Query: 595 YDYNKAQVPGPLTPEMEARQATRKREQKAARRQREEQQQRQ----------QEQEERERE 644
+++ + + ++ K E++A R+E Q + EQ +E
Sbjct: 266 LRFSRGR-------SLRKKRERLKEERRAQSVPRDEVAQSKGSVSAGDTPSSEQAVARKE 318
Query: 645 EQRRFAALSDREKRALAAERRLA-AQLGAPTSPIP 678
E R + E RA RR + ++ A + P P
Sbjct: 319 EAREEFLSASPEPRAKDDRRRKSRPKVSAFSDPTP 353
Score = 31.2 bits (69), Expect = 3.5
Identities = 17/31 (54%), Positives = 20/31 (64%)
Query: 535 GFTLLHAAAAAGRGSVVRLLLEAGADPTVQD 565
G T LH AA G VV++LL+AG D VQD
Sbjct: 42 GRTPLHLAANKGHLPVVQILLKAGCDLDVQD 72
>gi|30425444 ankyrin repeat and kinase domain containing 1 [Homo
sapiens]
Length = 765
Score = 42.4 bits (98), Expect = 0.002
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 8/105 (7%)
Query: 495 WNALLAACRAGDVGVLKLQLAPSPADPRVLSLLSAPLGSGGFTLLHAAAAAGRGSVVRLL 554
W L A G + ++ L LA S A+ LG+ +T LH AA G +VV L
Sbjct: 594 WTPLHLAAYKGHLEIIHL-LAESHAN-------MGALGAVNWTPLHLAARHGEEAVVSAL 645
Query: 555 LEAGADPTVQDSRARPPYTVAADKSTRNEFRRFMEKNPDAYDYNK 599
L+ GADP + P +A +ST +E + + + NK
Sbjct: 646 LQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNK 690
Score = 35.4 bits (80), Expect = 0.19
Identities = 31/106 (29%), Positives = 44/106 (41%), Gaps = 10/106 (9%)
Query: 493 ELWNALLAACRAGDVGVLKLQLAPSPADPRVLSLLSAPLGSGGFTLLHAAAAAGRGSVVR 552
E W L A + V +L L ADP + + G T LH AA G S+V+
Sbjct: 460 EGWTPLHLAAQNNFENVARL-LVSRQADPNLHE-------AEGKTPLHVAAYFGHVSLVK 511
Query: 553 LLLEAGADPTVQDSRARPPYTVAADKSTRNEFRRFMEKN--PDAYD 596
LL GA+ Q R P +A ++ + ++ PDA D
Sbjct: 512 LLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALD 557
Score = 34.7 bits (78), Expect = 0.32
Identities = 37/109 (33%), Positives = 47/109 (43%), Gaps = 17/109 (15%)
Query: 481 PLLDEAKAPGQPELWNALLA----ACRAGDVGVLKLQLAPSPADPRVLSLLSAPLGSG-- 534
PLL A+ QP+L LLA A R + G L A D LL L G
Sbjct: 398 PLLIAAQDQ-QPDLCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTARLL---LDHGAC 453
Query: 535 -------GFTLLHAAAAAGRGSVVRLLLEAGADPTVQDSRARPPYTVAA 576
G+T LH AA +V RLL+ ADP + ++ + P VAA
Sbjct: 454 VDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAA 502
Score = 33.5 bits (75), Expect = 0.71
Identities = 19/55 (34%), Positives = 31/55 (56%), Gaps = 1/55 (1%)
Query: 535 GFTLLHAAAAAGRGSVVRLLLEAGADPTVQDSRARPPYTVAADKSTRNEFRRFME 589
G+T H AA G +++++L+EAGA VQD + P +A +S + F+E
Sbjct: 692 GWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLAL-RSRKQGIMSFLE 745
>gi|55956910 meningioma 1 [Homo sapiens]
Length = 1320
Score = 42.4 bits (98), Expect = 0.002
Identities = 20/59 (33%), Positives = 43/59 (72%), Gaps = 4/59 (6%)
Query: 619 REQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRL----AAQLGAP 673
++Q+ ++Q+++QQQ+QQ+Q+++++++QR+ AAL ++ + ++RL AQLG P
Sbjct: 523 QQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHP 581
>gi|21361517 UBX domain protein 1 [Homo sapiens]
Length = 312
Score = 42.4 bits (98), Expect = 0.002
Identities = 32/116 (27%), Positives = 57/116 (49%), Gaps = 6/116 (5%)
Query: 554 LLEAGADPTVQDSRARPPYTVAADKSTRNEFRRFMEKNPDAYDYNKAQVPGPLTPEMEAR 613
L+E DP V + P + + T +E + +E + A K P E E +
Sbjct: 39 LMEHEDDPDVDEPLETPLGHILGREPTSSE-QGGLEGSGSAAGEGK-----PALSEEERQ 92
Query: 614 QATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRLAAQ 669
+ T++ + A++QRE +++ ++E ERER+ +R+ LS +R E R AA+
Sbjct: 93 EQTKRMLELVAQKQREREEREEREALERERQRRRQGQELSAARQRLQEDEMRRAAE 148
Score = 31.6 bits (70), Expect = 2.7
Identities = 20/62 (32%), Positives = 35/62 (56%), Gaps = 4/62 (6%)
Query: 613 RQATRKREQKAARRQREEQQQRQQEQEERER---EEQRRFAALSDREK-RALAAERRLAA 668
R+ + E++A R+R+ ++Q Q+ R+R +E RR A REK LAA +R+
Sbjct: 107 REREEREEREALERERQRRRQGQELSAARQRLQEDEMRRAAEERRREKAEELAARQRVRE 166
Query: 669 QL 670
++
Sbjct: 167 KI 168
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 42.0 bits (97), Expect = 0.002
Identities = 17/75 (22%), Positives = 49/75 (65%)
Query: 595 YDYNKAQVPGPLTPEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSD 654
Y + Q+ L + + +Q ++++Q+ ++Q+++QQQ+QQ+Q+++++++Q+ +
Sbjct: 139 YKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAK 198
Query: 655 REKRALAAERRLAAQ 669
+++ +++LAAQ
Sbjct: 199 EQQQQQQQQQQLAAQ 213
Score = 37.7 bits (86), Expect = 0.038
Identities = 14/65 (21%), Positives = 43/65 (66%)
Query: 606 LTPEMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERR 665
L + + +Q ++++Q+ ++Q+++QQQ+QQ+Q+++++++Q +++++ ++
Sbjct: 151 LQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQL 210
Query: 666 LAAQL 670
A QL
Sbjct: 211 AAQQL 215
Score = 36.2 bits (82), Expect = 0.11
Identities = 14/61 (22%), Positives = 41/61 (67%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRLAA 668
+ + +Q ++++Q+ ++Q+++QQQ+QQ+Q+++ +Q + ++++ LAA++ +
Sbjct: 159 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQ 218
Query: 669 Q 669
Q
Sbjct: 219 Q 219
Score = 35.4 bits (80), Expect = 0.19
Identities = 13/60 (21%), Positives = 41/60 (68%)
Query: 613 RQATRKREQKAARRQREEQQQRQQEQEEREREEQRRFAALSDREKRALAAERRLAAQLGA 672
+Q ++++Q+ ++Q+++QQQ+QQ+Q+++++++Q++ ++ + +++ QL A
Sbjct: 153 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 212
Score = 30.0 bits (66), Expect = 7.9
Identities = 11/40 (27%), Positives = 28/40 (70%)
Query: 609 EMEARQATRKREQKAARRQREEQQQRQQEQEEREREEQRR 648
+ + Q K++Q+ Q +QQQ+QQ+Q+++++++Q++
Sbjct: 131 QQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQ 170
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,700,469
Number of Sequences: 37866
Number of extensions: 1666243
Number of successful extensions: 28908
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 525
Number of HSP's successfully gapped in prelim test: 384
Number of HSP's that attempted gapping in prelim test: 14079
Number of HSP's gapped (non-prelim): 8935
length of query: 726
length of database: 18,247,518
effective HSP length: 110
effective length of query: 616
effective length of database: 14,082,258
effective search space: 8674670928
effective search space used: 8674670928
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.