Guide to the Human Genome
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Name: C8A Sequence: fasta or formatted (584aa) NCBI GI: 4557389
Description:

complement component 8, alpha polypeptide precursor

Referenced in:

Complement
Additional Genes in Development

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.0         35           2
 C cysteine            5.1         30           1
 D aspartate           6.7         39           2
 E glutamate           5.7         33           1
 F phenylalanine       3.8         22           2
 G glycine             9.6         56           3
 H histidine           1.5          9           1
 I isoleucine          4.8         28           2
 K lysine              5.5         32           2
 L leucine             6.7         39           2
 M methionine          2.1         12           1
 N asparagine          3.9         23           2
 P proline             3.1         18           1
 Q glutamine           5.7         33           1
 R arginine            6.0         35           3
 S serine              8.0         47           3
 T threonine           5.3         31           2
 V valine              4.6         27           2
 W tryptophan          1.5          9           1
 Y tyrosine            4.5         26           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   complement component 8, alpha polypeptide precursor [... 
C8B                   0.262   complement component 8, beta polypeptide preproprotei...
C6                    0.235   complement component 6 precursor 
C6                    0.235   complement component 6 precursor 
C7                    0.207   complement component 7 precursor 
C9                    0.197   complement component 9 precursor 
PRF1                  0.035   perforin 1 precursor 
PRF1                  0.035   perforin 1 precursor 
UNC5C                 0.031   unc5C 
ADAMTS17              0.031   ADAM metallopeptidase with thrombospondin type 1 mo...
ADAMTS8               0.031   ADAM metallopeptidase with thrombospondin type 1 mo...
ADAMTS20              0.031   a disintegrin-like and metalloprotease with thrombo...
ADAMTS15              0.030   a disintegrin-like and metalloprotease (reprolysin t...
THBS2                 0.028   thrombospondin 2 precursor 
HMCN1                 0.027   hemicentin 1 
ADAMTS5               0.027   ADAM metallopeptidase with thrombospondin type 1 mo...
ADAMTS1               0.027   ADAM metallopeptidase with thrombospondin type 1 mot...
UNC5D                 0.027   unc-5 homolog D 
ADAMTS13              0.027   ADAM metallopeptidase with thrombospondin type 1 mot...
ADAMTS13              0.027   ADAM metallopeptidase with thrombospondin type 1 mot...
ADAMTS13              0.027   ADAM metallopeptidase with thrombospondin type 1 mot...
UNC5B                 0.027   unc-5 homolog B 
ADAMTS18              0.027   ADAM metallopeptidase with thrombospondin type 1 mot...
ADAMTS3               0.027   ADAM metallopeptidase with thrombospondin type 1 mot...
UNC5A                 0.027   netrin receptor Unc5h1 
ADAMTS9               0.026   ADAM metallopeptidase with thrombospondin type 1 mot...
ADAMTS16              0.026   ADAM metallopeptidase with thrombospondin type 1 mo...
SEMA5B                0.026   semaphorin 5B isoform 1 
ADAMTS6               0.026   ADAM metallopeptidase with thrombospondin type 1 mot...
THBS1                 0.025   thrombospondin 1 precursor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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