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Search of human proteins with 45505139
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|45505139 phosphoinositide-3-kinase adaptor protein 1 [Homo
sapiens]
(805 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|45505139 phosphoinositide-3-kinase adaptor protein 1 [Homo sa... 1628 0.0
gi|144953891 B-cell scaffold protein with ankyrin repeats 1 isof... 210 4e-54
gi|144953889 B-cell scaffold protein with ankyrin repeats 1 isof... 206 9e-53
gi|189011559 B-cell scaffold protein with ankyrin repeats 1 isof... 149 1e-35
gi|31563330 A-kinase anchor protein 13 isoform 1 [Homo sapiens] 45 2e-04
gi|21493029 A-kinase anchor protein 13 isoform 2 [Homo sapiens] 45 2e-04
gi|56549694 enabled homolog isoform a [Homo sapiens] 45 3e-04
gi|39930375 enabled homolog isoform b [Homo sapiens] 45 3e-04
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 44 6e-04
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 44 6e-04
gi|55741677 SET domain containing 1A [Homo sapiens] 44 8e-04
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 42 0.003
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 41 0.005
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 40 0.009
gi|122937434 Rho-guanine nucleotide exchange factor [Homo sapiens] 39 0.019
gi|209977080 REST corepressor 3 isoform a [Homo sapiens] 39 0.019
gi|8922733 REST corepressor 3 isoform d [Homo sapiens] 39 0.019
gi|4885649 SUMO-1 activating enzyme subunit 2 [Homo sapiens] 39 0.019
gi|171906575 drebrin-like isoform c [Homo sapiens] 39 0.019
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 39 0.025
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 39 0.025
gi|53831995 splicing factor 3a, subunit 1, 120kDa isoform 2 [Hom... 39 0.025
gi|5032087 splicing factor 3a, subunit 1, 120kDa isoform 1 [Homo... 39 0.025
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 39 0.025
gi|153792074 proline rich 12 [Homo sapiens] 39 0.025
gi|116284392 mucin 2 precursor [Homo sapiens] 37 0.056
gi|23397642 GREB1 protein isoform a [Homo sapiens] 37 0.056
gi|121674801 hepatocyte cell adhesion molecule [Homo sapiens] 37 0.056
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 37 0.056
gi|50593108 5' nucleotidase, cytosolic IB isoform 2 [Homo sapiens] 37 0.056
>gi|45505139 phosphoinositide-3-kinase adaptor protein 1 [Homo
sapiens]
Length = 805
Score = 1628 bits (4215), Expect = 0.0
Identities = 805/805 (100%), Positives = 805/805 (100%)
Query: 1 MAASGVPRGCDILIVYSPDAEEWCQYLQTLFLSSRQVRSQKILTHRLGPEASFSAEDLSL 60
MAASGVPRGCDILIVYSPDAEEWCQYLQTLFLSSRQVRSQKILTHRLGPEASFSAEDLSL
Sbjct: 1 MAASGVPRGCDILIVYSPDAEEWCQYLQTLFLSSRQVRSQKILTHRLGPEASFSAEDLSL 60
Query: 61 FLSTRCVVVLLSAELVQHFHKPALLPLLQRAFHPPHRVVRLLCGVRDSEEFLDFFPDWAH 120
FLSTRCVVVLLSAELVQHFHKPALLPLLQRAFHPPHRVVRLLCGVRDSEEFLDFFPDWAH
Sbjct: 61 FLSTRCVVVLLSAELVQHFHKPALLPLLQRAFHPPHRVVRLLCGVRDSEEFLDFFPDWAH 120
Query: 121 WQELTCDDEPETYVAAVKKAISEDSGCDSVTDTEPEDEKVVSYSKQQNLPTVTSPGNLMV 180
WQELTCDDEPETYVAAVKKAISEDSGCDSVTDTEPEDEKVVSYSKQQNLPTVTSPGNLMV
Sbjct: 121 WQELTCDDEPETYVAAVKKAISEDSGCDSVTDTEPEDEKVVSYSKQQNLPTVTSPGNLMV 180
Query: 181 VQPDRIRCGAETTVYVIVRCKLDDRVATEAEFSPEDSPSVRMEAKVENEYTISVKAPNLS 240
VQPDRIRCGAETTVYVIVRCKLDDRVATEAEFSPEDSPSVRMEAKVENEYTISVKAPNLS
Sbjct: 181 VQPDRIRCGAETTVYVIVRCKLDDRVATEAEFSPEDSPSVRMEAKVENEYTISVKAPNLS 240
Query: 241 SGNVSLKIYSGDLVVCETVISYYTDMEEIGNLLSNAANPVEFMCQAFKIVPYNTETLDKL 300
SGNVSLKIYSGDLVVCETVISYYTDMEEIGNLLSNAANPVEFMCQAFKIVPYNTETLDKL
Sbjct: 241 SGNVSLKIYSGDLVVCETVISYYTDMEEIGNLLSNAANPVEFMCQAFKIVPYNTETLDKL 300
Query: 301 LTESLKNNIPASGLHLFGINQLEEEDMMTNQRDEELPTLLHFAAKYGLKNLTALLLTCPG 360
LTESLKNNIPASGLHLFGINQLEEEDMMTNQRDEELPTLLHFAAKYGLKNLTALLLTCPG
Sbjct: 301 LTESLKNNIPASGLHLFGINQLEEEDMMTNQRDEELPTLLHFAAKYGLKNLTALLLTCPG 360
Query: 361 ALQAYSVANKHGHYPNTIAEKHGFRDLRQFIDEYVETVDMLKSHIKEELMHGEEADAVYE 420
ALQAYSVANKHGHYPNTIAEKHGFRDLRQFIDEYVETVDMLKSHIKEELMHGEEADAVYE
Sbjct: 361 ALQAYSVANKHGHYPNTIAEKHGFRDLRQFIDEYVETVDMLKSHIKEELMHGEEADAVYE 420
Query: 421 SMAHLSTDLLMKCSLNPGCDEDLYESMAAFVPAATEDLYVEMLQASTSNPIPGDGFSRAT 480
SMAHLSTDLLMKCSLNPGCDEDLYESMAAFVPAATEDLYVEMLQASTSNPIPGDGFSRAT
Sbjct: 421 SMAHLSTDLLMKCSLNPGCDEDLYESMAAFVPAATEDLYVEMLQASTSNPIPGDGFSRAT 480
Query: 481 KDSMIRKFLEGNSMGMTNLERDQCHLGQEEDVYHTVDDDEAFSVDLASRPPVPVPRPETT 540
KDSMIRKFLEGNSMGMTNLERDQCHLGQEEDVYHTVDDDEAFSVDLASRPPVPVPRPETT
Sbjct: 481 KDSMIRKFLEGNSMGMTNLERDQCHLGQEEDVYHTVDDDEAFSVDLASRPPVPVPRPETT 540
Query: 541 APGAHQLPDNEPYIFKVFAEKSQERPGNFYVSSESIRKGPPVRPWRDRPQSSIYDPFAGM 600
APGAHQLPDNEPYIFKVFAEKSQERPGNFYVSSESIRKGPPVRPWRDRPQSSIYDPFAGM
Sbjct: 541 APGAHQLPDNEPYIFKVFAEKSQERPGNFYVSSESIRKGPPVRPWRDRPQSSIYDPFAGM 600
Query: 601 KTPGQRQLITLQEQVKLGIVNVDEAVLHFKEWQLNQKKRSESFRFQQENLKRLRDSITRR 660
KTPGQRQLITLQEQVKLGIVNVDEAVLHFKEWQLNQKKRSESFRFQQENLKRLRDSITRR
Sbjct: 601 KTPGQRQLITLQEQVKLGIVNVDEAVLHFKEWQLNQKKRSESFRFQQENLKRLRDSITRR 660
Query: 661 QREKQKSGKQTDLEITVPIRHSQHLPAKVEFGVYESGPRKSVIPPRTELRRGDWKTDSTS 720
QREKQKSGKQTDLEITVPIRHSQHLPAKVEFGVYESGPRKSVIPPRTELRRGDWKTDSTS
Sbjct: 661 QREKQKSGKQTDLEITVPIRHSQHLPAKVEFGVYESGPRKSVIPPRTELRRGDWKTDSTS 720
Query: 721 STASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEVTRSRSPGPPQVDGTPTMSLERPPRVP 780
STASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEVTRSRSPGPPQVDGTPTMSLERPPRVP
Sbjct: 721 STASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEVTRSRSPGPPQVDGTPTMSLERPPRVP 780
Query: 781 PRAASQRPPTRETFHPPPPVPPRGR 805
PRAASQRPPTRETFHPPPPVPPRGR
Sbjct: 781 PRAASQRPPTRETFHPPPPVPPRGR 805
>gi|144953891 B-cell scaffold protein with ankyrin repeats 1 isoform
1 [Homo sapiens]
Length = 785
Score = 210 bits (535), Expect = 4e-54
Identities = 201/738 (27%), Positives = 322/738 (43%), Gaps = 114/738 (15%)
Query: 11 DILIVYSPDAEEWCQYLQTLFLSSRQVRSQKILTHRLGPEASFSAEDLSLFLSTRCVVVL 70
DI+++Y DAEEW YL +FL V+ + IL +RL SF +L S +C +++
Sbjct: 28 DIIMIYEEDAEEWALYLTEVFL--HVVKREAILLYRL-ENFSFRHLELLNLTSYKCKLLI 84
Query: 71 LSAELVQHFHKPALLPLLQRAFHPPHRVVRLLCGVRDSEEFLDFFPDWAHWQELTCDDEP 130
LS L++ P L++ H P VV LLCGV+ S++ + E++ + EP
Sbjct: 85 LSNSLLRDL-TPKKCQFLEKILHSPKSVVTLLCGVKSSDQLYELLNISQSRWEISTEQEP 143
Query: 131 ETYVAAVKKAISEDSG----CDSVTDTEPEDEKVVSYSKQQNLPTVTSPGN--LMVVQPD 184
E Y++ ++ I +DS + TD + +S K+ + S L VV P
Sbjct: 144 EDYISVIQSIIFKDSEDYFEVNIPTDLRAKHSGEISERKEIEELSEASRNTIPLAVVLPT 203
Query: 185 RIRCGAETTVYVIVRCK-LDDRVATEAEFSPEDSPSVRMEAKVENEYTISVKAPNLSSGN 243
I C +++I+R + + D V E EF+ + +R + N+ +KA +G+
Sbjct: 204 EIPCENPGEIFIILRDEVIGDTV--EVEFTSSNK-RIRTRPALWNKKVWCMKALEFPAGS 260
Query: 244 VSLKIYSGDLVVCETVISYYTDMEEIGNLLSNAANPVEFMCQAFKIVPYNTETLDKLLTE 303
V + +Y +V T I YY + L A+ E +CQ + E LD +LT
Sbjct: 261 VHVNVYCDGIVKATTKIKYYPTAKA-KECLFRMADSGESLCQN------SIEELDGVLTS 313
Query: 304 SLKNNIPASGLHLFGINQLEEEDMMTNQRD--EELPTLLHFAAKYGLKNLTALLLTCPGA 361
K+ IP + L+ E N+ +ELPTLLH AAK+GLKNL LL C GA
Sbjct: 314 IFKHEIP-----YYEFQSLQTEICSQNKYTHFKELPTLLHCAAKFGLKNLAIHLLQCSGA 368
Query: 362 LQAYSVANKHGHYPNTIAEKHGFRDLRQFIDEY-VETVDMLKS----------------- 403
A + N G P IAE+HG ++L++ +++ ++ +D+
Sbjct: 369 TWASKMKNMEGSDPAHIAERHGHKELKKIFEDFSIQEIDINNEQENDYEEDIASFSTYIP 428
Query: 404 -------HIKEELMHGEEADAVY------ESMAHLSTDLLMKCSLNPGCD--EDLYESMA 448
H + +G+ AD E + S L G + ED Y+ +
Sbjct: 429 STQNPAFHHESRKTYGQSADGAEANEMEGEGKQNGSGMETKHSPLEVGSESSEDQYDDLY 488
Query: 449 AFVPAATEDLYVEMLQASTSNPIP-----GDGF--------------------SRATKDS 483
F+P A + + S+ P+P + F S+
Sbjct: 489 VFIPGADPENNSQEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHP 548
Query: 484 MIRKFLEGNSMGMTNLERDQCHLGQEEDVYHTVD-DDEAFSVDLA--------------- 527
+R+ G + ++ +EED Y + DD + + LA
Sbjct: 549 GVRQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSFII 608
Query: 528 SRPPVPVPRPETTAPGAHQLPDNEPYIFKVFAEKSQERPGNFYVSSESIRKGPPVRPWRD 587
+RPP P PRP + P + PYI +VF +K+ R S + G P + R
Sbjct: 609 NRPPAPTPRPTSIPP----KEETTPYIAQVFQQKTARRQ-----SDDDKFCGLPKKQDRA 659
Query: 588 RPQSSIYDPFAGMKTPGQRQLITLQEQVKLGIVNVDEAVLHFKEWQLNQKKRSESFRFQQ 647
R +S + G T GQ +LI LQE+VK G +++DEA+ FK WQ+ +S QQ
Sbjct: 660 RIESPAFSTLRGCLTDGQEELILLQEKVKNGKMSMDEALEKFKHWQMG---KSGLEMIQQ 716
Query: 648 ENLKRLRDSITRRQREKQ 665
E L++LRD I ++ E++
Sbjct: 717 EKLRQLRDCIIGKRPEEE 734
>gi|144953889 B-cell scaffold protein with ankyrin repeats 1 isoform
2 [Homo sapiens]
Length = 755
Score = 206 bits (523), Expect = 9e-53
Identities = 199/735 (27%), Positives = 319/735 (43%), Gaps = 114/735 (15%)
Query: 14 IVYSPDAEEWCQYLQTLFLSSRQVRSQKILTHRLGPEASFSAEDLSLFLSTRCVVVLLSA 73
++Y DAEEW YL +FL V+ + IL +RL SF +L S +C +++LS
Sbjct: 1 MIYEEDAEEWALYLTEVFL--HVVKREAILLYRL-ENFSFRHLELLNLTSYKCKLLILSN 57
Query: 74 ELVQHFHKPALLPLLQRAFHPPHRVVRLLCGVRDSEEFLDFFPDWAHWQELTCDDEPETY 133
L++ P L++ H P VV LLCGV+ S++ + E++ + EPE Y
Sbjct: 58 SLLRDL-TPKKCQFLEKILHSPKSVVTLLCGVKSSDQLYELLNISQSRWEISTEQEPEDY 116
Query: 134 VAAVKKAISEDSG----CDSVTDTEPEDEKVVSYSKQQNLPTVTSPGN--LMVVQPDRIR 187
++ ++ I +DS + TD + +S K+ + S L VV P I
Sbjct: 117 ISVIQSIIFKDSEDYFEVNIPTDLRAKHSGEISERKEIEELSEASRNTIPLAVVLPTEIP 176
Query: 188 CGAETTVYVIVRCK-LDDRVATEAEFSPEDSPSVRMEAKVENEYTISVKAPNLSSGNVSL 246
C +++I+R + + D V E EF+ + +R + N+ +KA +G+V +
Sbjct: 177 CENPGEIFIILRDEVIGDTV--EVEFTSSNK-RIRTRPALWNKKVWCMKALEFPAGSVHV 233
Query: 247 KIYSGDLVVCETVISYYTDMEEIGNLLSNAANPVEFMCQAFKIVPYNTETLDKLLTESLK 306
+Y +V T I YY + L A+ E +CQ + E LD +LT K
Sbjct: 234 NVYCDGIVKATTKIKYYPTAKA-KECLFRMADSGESLCQN------SIEELDGVLTSIFK 286
Query: 307 NNIPASGLHLFGINQLEEEDMMTNQRD--EELPTLLHFAAKYGLKNLTALLLTCPGALQA 364
+ IP + L+ E N+ +ELPTLLH AAK+GLKNL LL C GA A
Sbjct: 287 HEIP-----YYEFQSLQTEICSQNKYTHFKELPTLLHCAAKFGLKNLAIHLLQCSGATWA 341
Query: 365 YSVANKHGHYPNTIAEKHGFRDLRQFIDEY-VETVDMLKS-------------------- 403
+ N G P IAE+HG ++L++ +++ ++ +D+
Sbjct: 342 SKMKNMEGSDPAHIAERHGHKELKKIFEDFSIQEIDINNEQENDYEEDIASFSTYIPSTQ 401
Query: 404 ----HIKEELMHGEEADAVY------ESMAHLSTDLLMKCSLNPGCD--EDLYESMAAFV 451
H + +G+ AD E + S L G + ED Y+ + F+
Sbjct: 402 NPAFHHESRKTYGQSADGAEANEMEGEGKQNGSGMETKHSPLEVGSESSEDQYDDLYVFI 461
Query: 452 PAATEDLYVEMLQASTSNPIP-----GDGF--------------------SRATKDSMIR 486
P A + + S+ P+P + F S+ +R
Sbjct: 462 PGADPENNSQEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVR 521
Query: 487 KFLEGNSMGMTNLERDQCHLGQEEDVYHTVD-DDEAFSVDLA---------------SRP 530
+ G + ++ +EED Y + DD + + LA +RP
Sbjct: 522 QETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRP 581
Query: 531 PVPVPRPETTAPGAHQLPDNEPYIFKVFAEKSQERPGNFYVSSESIRKGPPVRPWRDRPQ 590
P P PRP + P + PYI +VF +K+ R S + G P + R R +
Sbjct: 582 PAPTPRPTSIPP----KEETTPYIAQVFQQKTARRQ-----SDDDKFCGLPKKQDRARIE 632
Query: 591 SSIYDPFAGMKTPGQRQLITLQEQVKLGIVNVDEAVLHFKEWQLNQKKRSESFRFQQENL 650
S + G T GQ +LI LQE+VK G +++DEA+ FK WQ+ +S QQE L
Sbjct: 633 SPAFSTLRGCLTDGQEELILLQEKVKNGKMSMDEALEKFKHWQMG---KSGLEMIQQEKL 689
Query: 651 KRLRDSITRRQREKQ 665
++LRD I ++ E++
Sbjct: 690 RQLRDCIIGKRPEEE 704
>gi|189011559 B-cell scaffold protein with ankyrin repeats 1 isoform
3 [Homo sapiens]
Length = 652
Score = 149 bits (376), Expect = 1e-35
Identities = 151/565 (26%), Positives = 239/565 (42%), Gaps = 104/565 (18%)
Query: 178 LMVVQPDRIRCGAETTVYVIVRCK-LDDRVATEAEFSPEDSPSVRMEAKVENEYTISVKA 236
L VV P I C +++I+R + + D V E EF+ + +R + N+ +KA
Sbjct: 64 LAVVLPTEIPCENPGEIFIILRDEVIGDTV--EVEFTSSNK-RIRTRPALWNKKVWCMKA 120
Query: 237 PNLSSGNVSLKIYSGDLVVCETVISYYTDMEEIGNLLSNAANPVEFMCQAFKIVPYNTET 296
+G+V + +Y +V T I YY + L A+ E +CQ + E
Sbjct: 121 LEFPAGSVHVNVYCDGIVKATTKIKYYPTAKA-KECLFRMADSGESLCQN------SIEE 173
Query: 297 LDKLLTESLKNNIPASGLHLFGINQLEEEDMMTNQRD--EELPTLLHFAAKYGLKNLTAL 354
LD +LT K+ IP + L+ E N+ +ELPTLLH AAK+GLKNL
Sbjct: 174 LDGVLTSIFKHEIP-----YYEFQSLQTEICSQNKYTHFKELPTLLHCAAKFGLKNLAIH 228
Query: 355 LLTCPGALQAYSVANKHGHYPNTIAEKHGFRDLRQFIDEY-VETVDMLKS---------- 403
LL C GA A + N G P IAE+HG ++L++ +++ ++ +D+
Sbjct: 229 LLQCSGATWASKMKNMEGSDPAHIAERHGHKELKKIFEDFSIQEIDINNEQENDYEEDIA 288
Query: 404 --------------HIKEELMHGEEADAVY------ESMAHLSTDLLMKCSLNPGCD--E 441
H + +G+ AD E + S L G + E
Sbjct: 289 SFSTYIPSTQNPAFHHESRKTYGQSADGAEANEMEGEGKQNGSGMETKHSPLEVGSESSE 348
Query: 442 DLYESMAAFVPAATEDLYVEMLQASTSNPIP-----GDGF-------------------- 476
D Y+ + F+P A + + S+ P+P + F
Sbjct: 349 DQYDDLYVFIPGADPENNSQEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMER 408
Query: 477 SRATKDSMIRKFLEGNSMGMTNLERDQCHLGQEEDVYHTVD-DDEAFSVDLA-------- 527
S+ +R+ G + ++ +EED Y + DD + + LA
Sbjct: 409 SQNWGHPGVRQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKT 468
Query: 528 -------SRPPVPVPRPETTAPGAHQLPDNEPYIFKVFAEKSQERPGNFYVSSESIRKGP 580
+RPP P PRP + P + PYI +VF +K+ R S + G
Sbjct: 469 GSRSFIINRPPAPTPRPTSIPP----KEETTPYIAQVFQQKTARRQ-----SDDDKFCGL 519
Query: 581 PVRPWRDRPQSSIYDPFAGMKTPGQRQLITLQEQVKLGIVNVDEAVLHFKEWQLNQKKRS 640
P + R R +S + G T GQ +LI LQE+VK G +++DEA+ FK WQ+ +S
Sbjct: 520 PKKQDRARIESPAFSTLRGCLTDGQEELILLQEKVKNGKMSMDEALEKFKHWQMG---KS 576
Query: 641 ESFRFQQENLKRLRDSITRRQREKQ 665
QQE L++LRD I ++ E++
Sbjct: 577 GLEMIQQEKLRQLRDCIIGKRPEEE 601
>gi|31563330 A-kinase anchor protein 13 isoform 1 [Homo sapiens]
Length = 2817
Score = 45.4 bits (106), Expect = 2e-04
Identities = 23/56 (41%), Positives = 32/56 (57%)
Query: 338 TLLHFAAKYGLKNLTALLLTCPGALQAYSVANKHGHYPNTIAEKHGFRDLRQFIDE 393
TL+HFA + GL LT LL PG A S+ N+ G P ++A + G+ L Q + E
Sbjct: 166 TLMHFAVRLGLLRLTWFLLQKPGGRGALSIHNQEGATPVSLALERGYHKLHQLLTE 221
>gi|21493029 A-kinase anchor protein 13 isoform 2 [Homo sapiens]
Length = 2813
Score = 45.4 bits (106), Expect = 2e-04
Identities = 23/56 (41%), Positives = 32/56 (57%)
Query: 338 TLLHFAAKYGLKNLTALLLTCPGALQAYSVANKHGHYPNTIAEKHGFRDLRQFIDE 393
TL+HFA + GL LT LL PG A S+ N+ G P ++A + G+ L Q + E
Sbjct: 166 TLMHFAVRLGLLRLTWFLLQKPGGRGALSIHNQEGATPVSLALERGYHKLHQLLTE 221
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 44.7 bits (104), Expect = 3e-04
Identities = 47/181 (25%), Positives = 73/181 (40%), Gaps = 17/181 (9%)
Query: 636 QKKRSESFRFQQENLKRLRDSITRRQR--EKQKSGKQTDLEITVPI-RHSQHLPAKVEFG 692
+++R E R +QE L+R R R++R +++ +Q LE + R Q +
Sbjct: 177 ERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLE 236
Query: 693 VYESGPRKSVIPPRTELRRGDWKTDST-SSTASSTSNRSSTRSLLSVSSGMEGDNEDNEV 751
E ++ + E + +W+ + SS A+ S + S+L SS E +
Sbjct: 237 RLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQ 296
Query: 752 PEVTRSRS----------PGPPQVDGTPTMSLERPPRVPPRAASQRPPTRETFHPPPPVP 801
P T S+ P PP G S+ PP P PP T PPPP P
Sbjct: 297 PAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPP---PPGPPPPPPLPSTGPPPPPPP 353
Query: 802 P 802
P
Sbjct: 354 P 354
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 44.7 bits (104), Expect = 3e-04
Identities = 47/181 (25%), Positives = 73/181 (40%), Gaps = 17/181 (9%)
Query: 636 QKKRSESFRFQQENLKRLRDSITRRQR--EKQKSGKQTDLEITVPI-RHSQHLPAKVEFG 692
+++R E R +QE L+R R R++R +++ +Q LE + R Q +
Sbjct: 177 ERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLE 236
Query: 693 VYESGPRKSVIPPRTELRRGDWKTDST-SSTASSTSNRSSTRSLLSVSSGMEGDNEDNEV 751
E ++ + E + +W+ + SS A+ S + S+L SS E +
Sbjct: 237 RLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQ 296
Query: 752 PEVTRSRS----------PGPPQVDGTPTMSLERPPRVPPRAASQRPPTRETFHPPPPVP 801
P T S+ P PP G S+ PP P PP T PPPP P
Sbjct: 297 PAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPP---PPGPPPPPPLPSTGPPPPPPP 353
Query: 802 P 802
P
Sbjct: 354 P 354
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 43.9 bits (102), Expect = 6e-04
Identities = 29/84 (34%), Positives = 38/84 (45%), Gaps = 7/84 (8%)
Query: 719 TSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEVTRSRSPGPPQVDGTPTMSLERPPR 778
+SS ASST + + +S G + + + SPG PQ+ G PTM + PP
Sbjct: 514 SSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTM-VPLPPG 572
Query: 779 VPPRAASQRPPTRETFHPPPPVPP 802
V P PP PPPP PP
Sbjct: 573 VQPPLPPGAPP------PPPPPPP 590
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 43.9 bits (102), Expect = 6e-04
Identities = 29/84 (34%), Positives = 38/84 (45%), Gaps = 7/84 (8%)
Query: 719 TSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEVTRSRSPGPPQVDGTPTMSLERPPR 778
+SS ASST + + +S G + + + SPG PQ+ G PTM + PP
Sbjct: 514 SSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTM-VPLPPG 572
Query: 779 VPPRAASQRPPTRETFHPPPPVPP 802
V P PP PPPP PP
Sbjct: 573 VQPPLPPGAPP------PPPPPPP 590
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 43.5 bits (101), Expect = 8e-04
Identities = 33/109 (30%), Positives = 46/109 (42%), Gaps = 19/109 (17%)
Query: 713 DWKTDSTSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEVTRSRSPGPPQVD------ 766
D ++ S+SS++SS+S+ SS+ S S S D E+ E P S SP P +V
Sbjct: 1032 DSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAP 1091
Query: 767 ----------GTPTMSL---ERPPRVPPRAASQRPPTRETFHPPPPVPP 802
G+P L E P P + PP+ P PP P
Sbjct: 1092 VEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGP 1140
Score = 38.1 bits (87), Expect = 0.033
Identities = 34/114 (29%), Positives = 47/114 (41%), Gaps = 26/114 (22%)
Query: 716 TDSTSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEVP------------------EVTRS 757
T +T+S+++S+S+ SS+ S S SS + + D P TR
Sbjct: 331 TAATASSSASSSSLSSSSSSSSSSSSSQFRSSDANYPAYYESWNRYQRHTSYPPRRATRE 390
Query: 758 RSPGPPQVDGT-----PTMSLERPPRVPPRAASQ--RPPTRETFHPPPPVPPRG 804
PG P + T P+ + PP P R Q RPP E P PP P G
Sbjct: 391 EPPGAPFAENTAERFPPSYTSYLPPE-PSRPTDQDYRPPASEAPPPEPPEPGGG 443
Score = 32.0 bits (71), Expect = 2.3
Identities = 26/90 (28%), Positives = 35/90 (38%), Gaps = 11/90 (12%)
Query: 724 SSTSNRSSTRSLLSVSSGMEGDNED---NEVPEVTRSRSPGPPQVDGTP------TMSLE 774
S +N + S S ME ++D + P T + P PP P ++ L
Sbjct: 565 SPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTPPQQPPPPPPPPPPPPPYLASLPLG 624
Query: 775 RPPRVPPRAASQRP--PTRETFHPPPPVPP 802
PP P RP P + PPPP PP
Sbjct: 625 YPPHQPAYLLPPRPDGPPPPEYPPPPPPPP 654
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 41.6 bits (96), Expect = 0.003
Identities = 53/211 (25%), Positives = 81/211 (38%), Gaps = 50/211 (23%)
Query: 630 KEWQLNQKKRSESFRFQQENLKRLRDSITRRQREKQKSGKQTDLEITVPIRHSQHLPAKV 689
+EW+ + KR E R + RD ++REK+K GK P R ++ P K
Sbjct: 451 EEWERERAKRDEKDR-------QHRDRDREKEREKEK-GKPKPRSPQPPSRQAE--PPKK 500
Query: 690 EFGVY----------------ESGPRK----SVIPPRTELRRGDWKTDSTSSTASSTSNR 729
E P+K SV P R RR + +++S +S +S+R
Sbjct: 501 EAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSR 560
Query: 730 SS---------TRSLLSVSSGMEGDNEDNEVPEVTRSR--------SPGPPQVDGTPTMS 772
SS +RS S S + + +RSR SP P P++
Sbjct: 561 SSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIR 620
Query: 773 LERPPRVPPRAASQRPPTRETFHPPPPVPPR 803
+ P PP A ++ + PPP PP+
Sbjct: 621 TKGEPAPPPGKAGEKSVKKPA---PPPAPPQ 648
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 40.8 bits (94), Expect = 0.005
Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 3/87 (3%)
Query: 716 TDSTSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEVTRSRSPGPPQVDGTPTMSLER 775
+ S+SS++SS+S+ SS+ S S SS + D+ + E + + GP PT + ++
Sbjct: 2647 SSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQ 2706
Query: 776 PPRVPPRAASQRPPTRETFHPPPPVPP 802
+ P A S P ++T P P PP
Sbjct: 2707 AGKARPSAHS---PGKKTPAPQPQAPP 2730
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 40.0 bits (92), Expect = 0.009
Identities = 28/110 (25%), Positives = 45/110 (40%), Gaps = 24/110 (21%)
Query: 706 RTELRRGDWKTDSTSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEVTRSRSPGPP-- 763
+ ++ G K SS+ S +S+ SS+ D+ED+E +S+ G P
Sbjct: 685 KVDVIAGSSKMKGFSSSESESSSESSS-----------SDSEDSETEMAPKSKKKGHPGR 733
Query: 764 -----------QVDGTPTMSLERPPRVPPRAASQRPPTRETFHPPPPVPP 802
Q+ P ++PP P + PP ++ PPPP PP
Sbjct: 734 EQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPP 783
Score = 34.7 bits (78), Expect = 0.36
Identities = 25/90 (27%), Positives = 37/90 (41%), Gaps = 5/90 (5%)
Query: 715 KTDSTSSTASSTSNRSSTRSL-LSVSSGMEGDNEDNEVPEVTRSRSPGPPQVDGTPTMSL 773
+++S+S ++SS S S T S G G + + P V P
Sbjct: 702 ESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPP 761
Query: 774 ERPPRVPPRAASQRPPTRETFHPPPPVPPR 803
++PP PP Q+PP PPPP P+
Sbjct: 762 QQPPPPPPPQQQQQPPPP----PPPPSMPQ 787
Score = 30.0 bits (66), Expect = 8.9
Identities = 19/56 (33%), Positives = 23/56 (41%), Gaps = 8/56 (14%)
Query: 752 PEVTRSRSPGPPQVDGTPTMSLERPPRVPPRAASQRPPTR----ETFHPPPPVPPR 803
P T++ P PP V TP P V P Q P + PPPVPP+
Sbjct: 205 PPQTQTPQPNPPPVQATP----HPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQ 256
>gi|122937434 Rho-guanine nucleotide exchange factor [Homo sapiens]
Length = 1651
Score = 38.9 bits (89), Expect = 0.019
Identities = 44/201 (21%), Positives = 86/201 (42%), Gaps = 18/201 (8%)
Query: 338 TLLHFAAKYGLKNLTALLLTCPGALQAYSVANKHGHYPNTIAEKHG----FRDLRQFIDE 393
+LLH A ++GL L+ L PG +QA ++ N+ G P +A + G D+ F
Sbjct: 165 SLLHLAMRWGLAKLSQFFLCLPGGVQALALPNEEGATPLDLALREGHSKLVEDVTNFQGR 224
Query: 394 YVETVDMLKSHIKEELMHGEEADAVYESMAHLSTDLL-MKCSLNPGCDEDLYESMAAFVP 452
+ + ++ + L + ++ + ++ H + LL L D + AF P
Sbjct: 225 WSPSFSRVQLSEEASLHYIHSSETLTLTLNHTAEHLLEADIKLFRKYFWDRAFLVKAFEP 284
Query: 453 AATEDLYVEMLQASTSNPIPGDGFSRATKDSMIRKFLEGNSMGMTNLERDQCHLGQ--EE 510
A + T+ P G K+S+ + ++ +++R + + Q E
Sbjct: 285 EARP-------EERTAMPSSGAETEEEIKNSVSSR----SAAEKEDIKRVKSLVVQHNEH 333
Query: 511 DVYHTVDDDEAFSVDLASRPP 531
+ H++D D +F + S+PP
Sbjct: 334 EDQHSLDLDRSFDILKKSKPP 354
>gi|209977080 REST corepressor 3 isoform a [Homo sapiens]
Length = 553
Score = 38.9 bits (89), Expect = 0.019
Identities = 26/101 (25%), Positives = 44/101 (43%), Gaps = 11/101 (10%)
Query: 713 DWKTD--STSSTASSTSNRSSTRSLLSVSSGMEGDNEDN-EVPEVTRSRSPGPPQVDGTP 769
+W+ + + +S +++ T+S +V SG D E+ + P+ R+ P PP TP
Sbjct: 401 EWEAEQGTQASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTP 460
Query: 770 T-----MSLERPPRVPPRAASQRPPTRETFHPPPPVPPRGR 805
T +L +P PP P PPP+ + R
Sbjct: 461 TPTAPIATLNQP---PPLLRPTLPAAPALHRQPPPLQQQAR 498
>gi|8922733 REST corepressor 3 isoform d [Homo sapiens]
Length = 495
Score = 38.9 bits (89), Expect = 0.019
Identities = 26/101 (25%), Positives = 44/101 (43%), Gaps = 11/101 (10%)
Query: 713 DWKTD--STSSTASSTSNRSSTRSLLSVSSGMEGDNEDN-EVPEVTRSRSPGPPQVDGTP 769
+W+ + + +S +++ T+S +V SG D E+ + P+ R+ P PP TP
Sbjct: 343 EWEAEQGTQASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTP 402
Query: 770 T-----MSLERPPRVPPRAASQRPPTRETFHPPPPVPPRGR 805
T +L +P PP P PPP+ + R
Sbjct: 403 TPTAPIATLNQP---PPLLRPTLPAAPALHRQPPPLQQQAR 440
>gi|4885649 SUMO-1 activating enzyme subunit 2 [Homo sapiens]
Length = 640
Score = 38.9 bits (89), Expect = 0.019
Identities = 41/154 (26%), Positives = 61/154 (39%), Gaps = 7/154 (4%)
Query: 608 LITLQEQV---KLGIVNVDEAVLHFKEWQLNQKKRSESFRFQQENLKRLRDSITRRQREK 664
++TLQ+++ K +V D + K L + E+ + N K+L + R
Sbjct: 461 VLTLQDKIVKEKFAMVAPDVQIEDGKGTILISSEEGET---EANNHKKLSEFGIRNGSRL 517
Query: 665 QKSGKQTDLEITVPIRHSQHLPAKVEFGVYESGPRKSVIPPRTELRRGDWKTDSTSSTAS 724
Q D + + I HS+ L VEF V P K V P + E S
Sbjct: 518 QADDFLQDYTLLINILHSEDLGKDVEFEVVGDAPEK-VGPKQAEDAAKSITNGSDDGAQP 576
Query: 725 STSNRSSTRSLLSVSSGMEGDNEDNEVPEVTRSR 758
STS +L V S E + + +V E RSR
Sbjct: 577 STSTAQEQDDVLIVDSDEEDSSNNADVSEEERSR 610
>gi|171906575 drebrin-like isoform c [Homo sapiens]
Length = 439
Score = 38.9 bits (89), Expect = 0.019
Identities = 43/179 (24%), Positives = 76/179 (42%), Gaps = 22/179 (12%)
Query: 633 QLNQKKRSESFRFQQENLKR---LRDSITRRQREKQKSGKQTDLEITVPIRHSQHLPAKV 689
+L +K+R+E + Q E +R LR++ R QR +++ G+ + T + +
Sbjct: 191 RLEEKRRAEEAQRQLEQERRERELREAARREQRYQEQGGEASPQSRTWEQQQEVVSRNRN 250
Query: 690 EFGVYESGPRKSVIPPRTELRRGDWKTDSTSSTASSTSNRSSTRSLLSVSSGMEGDNEDN 749
E G + ++S + PR ++ K + S+T+ S+ RS + +
Sbjct: 251 EQGSTCASLQESAVHPREIFKQ---KERAMSTTSISSPQPGKLRSPFLQKQLTQPETHFG 307
Query: 750 EVPEVTRSRSPGPPQVDGTPTMSLERP-PRVPP-------RAASQRPPTRETFHPPPPV 800
P SR P+ D + E P P PP A + PP +ETF+ PP+
Sbjct: 308 REPAAAISR----PRAD----LPAEEPAPSTPPCLVQAEEEAVYEEPPEQETFYEQPPL 358
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
sapiens]
Length = 2524
Score = 38.5 bits (88), Expect = 0.025
Identities = 35/181 (19%), Positives = 65/181 (35%), Gaps = 7/181 (3%)
Query: 624 EAVLHFKEWQLNQKKRSESFRFQQENLKRLRDSITRRQREKQKSGKQTDLEITVPIRHSQ 683
+ V K + N KKR Q++ ++ R+++K+ ++ P+ +
Sbjct: 644 KTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDE 703
Query: 684 HLPAKVEFGVYES--GPRKSVIPPRTELRRGDWKTDSTSSTASSTSNRSSTRSLLSVSSG 741
+ A G E +++ E+ RG+ +T + +S T + S + + +G
Sbjct: 704 EMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTG 763
Query: 742 MEGDNEDNEVPEVTRSRSPGPPQVDGTPTMSLERPPRVPPRAASQRPPTRETFHPPPPVP 801
G P T PP P + P P + + PT P P P
Sbjct: 764 QNGPK-----PPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAP 818
Query: 802 P 802
P
Sbjct: 819 P 819
Score = 35.8 bits (81), Expect = 0.16
Identities = 26/93 (27%), Positives = 35/93 (37%), Gaps = 6/93 (6%)
Query: 716 TDSTSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEVTRSRSPGPPQVDGTPTMSLE- 774
T + SS A S+ S+T S V GD P + G P+ + +P L+
Sbjct: 904 TTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDL 963
Query: 775 -----RPPRVPPRAASQRPPTRETFHPPPPVPP 802
R +PP P RE P P PP
Sbjct: 964 KQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPP 996
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 38.5 bits (88), Expect = 0.025
Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 9/94 (9%)
Query: 714 WKTDSTSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEVTRSRSPGPPQVDGTPTMSL 773
W+T T S S++S + R L ++ +G +G P + S SP P +P+
Sbjct: 154 WRTGKTVSPQSNSSRPTCARHL-TLGTG-DGGPAPPPAPS-SASSSPSPSPSSSSPSPPP 210
Query: 774 ERPPRVPPRAASQRPPTRETFHP------PPPVP 801
PP PP + R + FHP PPP P
Sbjct: 211 PPPPPAPPAPPAPRFDIYDPFHPTDEAYSPPPAP 244
>gi|53831995 splicing factor 3a, subunit 1, 120kDa isoform 2 [Homo
sapiens]
Length = 728
Score = 38.5 bits (88), Expect = 0.025
Identities = 63/309 (20%), Positives = 113/309 (36%), Gaps = 55/309 (17%)
Query: 507 GQEEDVYHTVD-DDEAFSVDLASRPPVPVPRPETTAPGAHQLPDNEPYIFKV-------F 558
G+ E+V V+ D+E + A PP + + +T + D+E KV
Sbjct: 253 GESEEVEMEVESDEEDDKQEKAEEPPSQLDQ-DTQVQDMDEGSDDEEEGQKVPPPPETPM 311
Query: 559 AEKSQERPGNFYVSSESIRKGPPVRPWRDRPQSSIYDPFAGMKTPGQRQLITLQEQVKLG 618
P V + K P P + P G K P + +QE +++G
Sbjct: 312 PPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASK----MQEHMRIG 367
Query: 619 IVNVDEAVLHFKEWQLNQKKRSESFRFQQENLKRLRDSITRRQREKQKSGKQTDLEITVP 678
+++ W ++R S R +Q + + + KQ + ++TD+
Sbjct: 368 LLD--------PRWL---EQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDI----- 411
Query: 679 IRHSQHLPAKVEFGVYESGPRKSVIPPRTELRRGDWKTDSTSSTASSTSNRSSTRSLLSV 738
FGV E+ K + E+++ + K + S + + ++ +++
Sbjct: 412 ------------FGVEETAIGKKI--GEEEIQKPEEKVTWDGHSGSMARTQQAAQANITL 457
Query: 739 SSGMEGDNEDNE-VPEVTRSRSPGP------PQVDGTPTMSLERPPRVPPRAASQRPPTR 791
+E ++ VPE GP PQ P+ + P PP + RPPT
Sbjct: 458 QEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTM 517
Query: 792 ETFHPPPPV 800
PPPV
Sbjct: 518 -----PPPV 521
Score = 30.0 bits (66), Expect = 8.9
Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 5/49 (10%)
Query: 752 PEVTRSRSPGPPQVDGTPTMSLERPPRVPPRAASQRPPTRETFHPPPPV 800
P +P PP + PT + PP P A + PP HPPPP+
Sbjct: 568 PSAPPIMAPRPPPMI-VPTAFVPAPPVAPVPAPAPMPPV----HPPPPM 611
>gi|5032087 splicing factor 3a, subunit 1, 120kDa isoform 1 [Homo
sapiens]
Length = 793
Score = 38.5 bits (88), Expect = 0.025
Identities = 63/309 (20%), Positives = 113/309 (36%), Gaps = 55/309 (17%)
Query: 507 GQEEDVYHTVD-DDEAFSVDLASRPPVPVPRPETTAPGAHQLPDNEPYIFKV-------F 558
G+ E+V V+ D+E + A PP + + +T + D+E KV
Sbjct: 318 GESEEVEMEVESDEEDDKQEKAEEPPSQLDQ-DTQVQDMDEGSDDEEEGQKVPPPPETPM 376
Query: 559 AEKSQERPGNFYVSSESIRKGPPVRPWRDRPQSSIYDPFAGMKTPGQRQLITLQEQVKLG 618
P V + K P P + P G K P + +QE +++G
Sbjct: 377 PPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASK----MQEHMRIG 432
Query: 619 IVNVDEAVLHFKEWQLNQKKRSESFRFQQENLKRLRDSITRRQREKQKSGKQTDLEITVP 678
+++ W ++R S R +Q + + + KQ + ++TD+
Sbjct: 433 LLD--------PRWL---EQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDI----- 476
Query: 679 IRHSQHLPAKVEFGVYESGPRKSVIPPRTELRRGDWKTDSTSSTASSTSNRSSTRSLLSV 738
FGV E+ K + E+++ + K + S + + ++ +++
Sbjct: 477 ------------FGVEETAIGKKI--GEEEIQKPEEKVTWDGHSGSMARTQQAAQANITL 522
Query: 739 SSGMEGDNEDNE-VPEVTRSRSPGP------PQVDGTPTMSLERPPRVPPRAASQRPPTR 791
+E ++ VPE GP PQ P+ + P PP + RPPT
Sbjct: 523 QEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTM 582
Query: 792 ETFHPPPPV 800
PPPV
Sbjct: 583 -----PPPV 586
Score = 30.0 bits (66), Expect = 8.9
Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 5/49 (10%)
Query: 752 PEVTRSRSPGPPQVDGTPTMSLERPPRVPPRAASQRPPTRETFHPPPPV 800
P +P PP + PT + PP P A + PP HPPPP+
Sbjct: 633 PSAPPIMAPRPPPMI-VPTAFVPAPPVAPVPAPAPMPPV----HPPPPM 676
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 38.5 bits (88), Expect = 0.025
Identities = 34/114 (29%), Positives = 49/114 (42%), Gaps = 14/114 (12%)
Query: 703 IPPRTELRRGDWKTDSTSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEVTRSRSPGP 762
+ R + RR + ++ S S ++SS+ + RS V +G G + P + S SP
Sbjct: 479 VQQRRQYRRQNQQSSSDSGSSSSSEDERPKRS--HVKNGEVGRRRRHS-PSRSASPSPRK 535
Query: 763 PQVDGTPTMSLERPPRVPP----RAASQRPPTRETFHPPPPV-------PPRGR 805
Q + +P R P PP R+ S PP R P PP PPR R
Sbjct: 536 RQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRR 589
Score = 37.0 bits (84), Expect = 0.073
Identities = 45/171 (26%), Positives = 68/171 (39%), Gaps = 38/171 (22%)
Query: 651 KRLRDSITRRQREKQKSGKQTDLEITVPIRHSQHLPAKVEFGVYESGPRKSVIPPRTELR 710
KR S++ + R K S ++ E P + +H P+ P+ S PP +R
Sbjct: 650 KRRSPSLSSKHR-KGSSPSRSTREARSPQPNKRHSPSP-----RPRAPQTSSSPP--PVR 701
Query: 711 RGDWKTDSTSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEVTRSRSPGPPQV----- 765
RG ++SS S STR + VS E ++ ++ SP P V
Sbjct: 702 RG-----ASSSPQRRQSPSPSTRPIRRVS-------RTPEPKKIKKAASPSPQSVRRVSS 749
Query: 766 ----DGTPTMSLERPPRVPPRAASQRP--------PTRETFHP-PPPVPPR 803
G+P + ++PP P SQ P P ++ P P P PPR
Sbjct: 750 SRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPR 800
Score = 36.2 bits (82), Expect = 0.12
Identities = 39/143 (27%), Positives = 49/143 (34%), Gaps = 9/143 (6%)
Query: 659 RRQREKQKSGKQTDLEITVPIRHSQHLPAKVEFGVYESGPRK-SVIPPRTELRRGDWKTD 717
R +R K+G+ P R + P K + G R+ S PP T RR +
Sbjct: 506 RPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSP--SP 563
Query: 718 STSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEVTRSRSPGPPQVDGTPTMSLERPP 777
+ T R S + P + R SP PP P PP
Sbjct: 564 APPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPP-----PKRRTASPP 618
Query: 778 RVPPRAASQRPPT-RETFHPPPP 799
P R AS PP R H PPP
Sbjct: 619 PPPKRRASPSPPPKRRVSHSPPP 641
Score = 30.4 bits (67), Expect = 6.8
Identities = 45/232 (19%), Positives = 79/232 (34%), Gaps = 19/232 (8%)
Query: 578 KGPPVRPWRDRPQSSIYDPFAGMKTPGQRQLITLQEQVKLGIVNVDEAVLHFKEWQLNQK 637
+ P P + + +P +K P ++ + + +K V E + KE + +
Sbjct: 208 RSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILK---VPKPEPIPEPKE--PSPE 262
Query: 638 KRSESFRFQQENLKRLRDSITRRQREKQKSGKQTDLEITVPIRHSQHLPAKVEFGVYESG 697
K S+ + +++ R R R R + +S T R + P +
Sbjct: 263 KNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPS 322
Query: 698 PRKSV----IPPRTELRRGDWKTDSTSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEVPE 753
PR+ +PP RR + S R + + LS SS + P+
Sbjct: 323 PRRRTPPRRMPPPPRHRR----------SRSPVRRRRRSSASLSGSSSSSSSSRSRSPPK 372
Query: 754 VTRSRSPGPPQVDGTPTMSLERPPRVPPRAASQRPPTRETFHPPPPVPPRGR 805
R+ PP+ + S P R + PP + P P R R
Sbjct: 373 KPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTR 424
Score = 30.0 bits (66), Expect = 8.9
Identities = 39/162 (24%), Positives = 54/162 (33%), Gaps = 21/162 (12%)
Query: 661 QREKQKSGKQTDLEITVPIRHSQHLPAKVEFGVYESGPRKSVIPPRTELRRGDWKTDSTS 720
+ E+ K GK + R + + S + P R+ ++ G+
Sbjct: 464 ESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRH 523
Query: 721 STASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEVTRSRSPGP---PQVDGTPTMS-LERP 776
S + S S S R +S P R RSP P P+ TPT R
Sbjct: 524 SPSRSAS--PSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRT 581
Query: 777 PRVPPRAASQRP-----PTRETFHP----------PPPVPPR 803
P PPR S P P + + P PPP P R
Sbjct: 582 PSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKR 623
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 38.5 bits (88), Expect = 0.025
Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 20/105 (19%)
Query: 714 WKTDSTSSTASSTSNRSSTRSLLSVS-----SGMEGDNEDNEVPEVTRSRSPGPPQVDGT 768
+ +D S A + + S S +S +G + + + P + PGPP + G
Sbjct: 1380 FSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGL 1439
Query: 769 PTMSL----------ERPPRVPPRAASQRPPTRETFHPPPPVPPR 803
P+ + E+PP PP A PT + PPPP PP+
Sbjct: 1440 PSANSNGTPEPPLLEEKPPPTPPPA-----PTPQPQPPPPPPPPQ 1479
Score = 32.7 bits (73), Expect = 1.4
Identities = 25/85 (29%), Positives = 31/85 (36%), Gaps = 23/85 (27%)
Query: 741 GMEGDNEDNEVPEVTRSRSPGPPQVD---------------GTPTMSLE--RPPRVP--- 780
G G ED P+ PGPP D TP + L+ +PP +P
Sbjct: 963 GKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTV 1022
Query: 781 ---PRAASQRPPTRETFHPPPPVPP 802
P Q P + PPPP PP
Sbjct: 1023 NAEPLGLIQSGPHQAAPPPPPPPPP 1047
Score = 31.2 bits (69), Expect = 4.0
Identities = 20/59 (33%), Positives = 24/59 (40%), Gaps = 5/59 (8%)
Query: 749 NEVPEVTRSRSPGPPQVDGTPTMSLERPPRVPP-RAASQRPP----TRETFHPPPPVPP 802
N PE PP PT + PP PP + A PP + PPPP+PP
Sbjct: 1445 NGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPP 1503
Score = 31.2 bits (69), Expect = 4.0
Identities = 18/43 (41%), Positives = 20/43 (46%), Gaps = 7/43 (16%)
Query: 760 PGPPQVDGTPTMSLERPPRVPPRAASQRPPTRETFHPPPPVPP 802
P PP + PT S PP +PP PP PPPP PP
Sbjct: 1483 PSPPPLVA-PTPSSPPPPPLPP------PPPPAMPSPPPPPPP 1518
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 37.4 bits (85), Expect = 0.056
Identities = 23/91 (25%), Positives = 36/91 (39%), Gaps = 4/91 (4%)
Query: 716 TDSTSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEVTRSRSPGPPQVDGTPTMSLER 775
T +T+ ++T + +T + +S P T + +P P PT +
Sbjct: 1528 TTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPS 1587
Query: 776 PPRV----PPRAASQRPPTRETFHPPPPVPP 802
PP + PP + PPT T PPP P
Sbjct: 1588 PPTITTTTPPPTTTPSPPTTTTTTPPPTTTP 1618
Score = 32.3 bits (72), Expect = 1.8
Identities = 25/107 (23%), Positives = 40/107 (37%), Gaps = 6/107 (5%)
Query: 696 SGPRKSVIPPRTELRRGDWKTDSTSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEVT 755
S P + PP T T + T ++T+ +T +++ P ++
Sbjct: 1400 SPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPIS 1459
Query: 756 RSRSPGPPQVDGTPTMSLERPPRVPPRAASQRPPTRETFHPPPPVPP 802
+ +P PP +P + PP P PPT T PPP P
Sbjct: 1460 TTTTP-PPTTTPSPPTTTPSPPTTTP-----SPPTTTTTTPPPTTTP 1500
Score = 31.6 bits (70), Expect = 3.1
Identities = 17/54 (31%), Positives = 21/54 (38%), Gaps = 4/54 (7%)
Query: 752 PEVTRSRSPGPPQVDGTPTMSLERPPR----VPPRAASQRPPTRETFHPPPPVP 801
P T + +P P PT + PP +PP PPT T PP P
Sbjct: 1604 PPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP 1657
Score = 30.8 bits (68), Expect = 5.2
Identities = 17/54 (31%), Positives = 21/54 (38%), Gaps = 3/54 (5%)
Query: 752 PEVTRSRSPGPPQVDGTPTMSLERPPRVP---PRAASQRPPTRETFHPPPPVPP 802
P T + +P P PT + PP P + PPT T PPP P
Sbjct: 1486 PPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTP 1539
>gi|23397642 GREB1 protein isoform a [Homo sapiens]
Length = 1949
Score = 37.4 bits (85), Expect = 0.056
Identities = 32/109 (29%), Positives = 50/109 (45%), Gaps = 15/109 (13%)
Query: 695 ESGPRKSVIPPRTELRRGDWKTDSTSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEV 754
E G S R+ ++R ++ S S +SS S+++S +L G E + +P+
Sbjct: 1103 ELGTEGSTSEKRSPMKRE--RSRSHDSASSSLSSKASGSAL-----GGESSAQPTALPQG 1155
Query: 755 TRSRSPGP--PQVDGTPTMSLERPPRVPPRAASQRPPTRETFHPPPPVP 801
+RSP P P +G +RP ASQ PP+ + H P P P
Sbjct: 1156 EHARSPQPRGPAEEGRAPGEKQRP------RASQGPPSAISRHSPGPTP 1198
>gi|121674801 hepatocyte cell adhesion molecule [Homo sapiens]
Length = 416
Score = 37.4 bits (85), Expect = 0.056
Identities = 24/94 (25%), Positives = 39/94 (41%), Gaps = 8/94 (8%)
Query: 715 KTDSTSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEVTRSRSPGPPQVDGTPTMSLE 774
K ++ + S R + +L + + E+N PE + PGPP +P +
Sbjct: 290 KPEADTLPRSGEQERKNPMALYILKDKDSPETEENPAPEPRSATEPGPPGYSVSPAVP-G 348
Query: 775 RPPRVP-------PRAASQRPPTRETFHPPPPVP 801
R P +P PR+ ++ P T T PP P
Sbjct: 349 RSPGLPIRSARRYPRSPARSPATGRTHSSPPRAP 382
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 37.4 bits (85), Expect = 0.056
Identities = 26/88 (29%), Positives = 35/88 (39%), Gaps = 2/88 (2%)
Query: 717 DSTSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEVTRSRSPGPPQVDGTPTMSLERP 776
+ T+ ASST + +S M+ + E ++ GP TPTM E
Sbjct: 1193 EQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEA 1252
Query: 777 PRVPPRAA--SQRPPTRETFHPPPPVPP 802
PP +RPP PPPP PP
Sbjct: 1253 AACPPHILPPEKRPPEPPGPPPPPPPPP 1280
Score = 30.0 bits (66), Expect = 8.9
Identities = 39/184 (21%), Positives = 69/184 (37%), Gaps = 18/184 (9%)
Query: 635 NQKKRSESFRFQQENLKRLR--------DSITRRQREKQKSGKQTDLEITVPIRHSQHLP 686
+ KK+ S R + ++ +R ++R+++E+ + ++ LP
Sbjct: 369 HSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGSPVFLP 428
Query: 687 AKVEFGVY--ESGPRKSVIPPRTELRRGDWKTDSTSSTASSTS-NRSSTRSLLSVSSGME 743
K V +SG +P +L + T+ + T +T SS + + E
Sbjct: 429 RKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGKVKLDENSE 488
Query: 744 GDNEDNEVPEVTRSRSPGPPQVD-----GTPTMSLERPPRVPPRAASQRPPTRETFHPPP 798
+ + TR P + + T T E PP +P A+ PP T PPP
Sbjct: 489 KHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASP--PPPLPTTTPPP 546
Query: 799 PVPP 802
PP
Sbjct: 547 QTPP 550
>gi|50593108 5' nucleotidase, cytosolic IB isoform 2 [Homo sapiens]
Length = 550
Score = 37.4 bits (85), Expect = 0.056
Identities = 42/163 (25%), Positives = 67/163 (41%), Gaps = 32/163 (19%)
Query: 646 QQENLKRLRDSITRRQREKQKSGKQTDLEITVPIRHSQHLPAKVEFGVYESGPRKSVIPP 705
Q++N +R S + EK+K +T + ++ G ES RK+
Sbjct: 8 QKKNEPGMRSSKESLEAEKRKESDKTGVRLS-------------NQGSQESSLRKT--DS 52
Query: 706 RTELRRGDWKTDSTS-STASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEVTRS-RSPGPP 763
R L R W S S ST + + + +R+ S+ + + + P + S PP
Sbjct: 53 RGYLVRSQWSRISRSPSTKAPSIDEPRSRN---TSAKLPSSSTSSRTPSTSPSLHDSSPP 109
Query: 764 QVDGTPTMSLERPPRVP--PRAASQRPPTRETFHPPPPVPPRG 804
+ G P++ +PP P PR+ RPPT PP P G
Sbjct: 110 PLSGQPSL---QPPASPQLPRSLDSRPPT-------PPEPDPG 142
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,912,925
Number of Sequences: 37866
Number of extensions: 1799851
Number of successful extensions: 12941
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 76
Number of HSP's successfully gapped in prelim test: 327
Number of HSP's that attempted gapping in prelim test: 10691
Number of HSP's gapped (non-prelim): 2214
length of query: 805
length of database: 18,247,518
effective HSP length: 110
effective length of query: 695
effective length of database: 14,082,258
effective search space: 9787169310
effective search space used: 9787169310
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.