Guide to the Human Genome
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Search of human proteins with 4506525

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4506525 rhomboid protease 1 [Homo sapiens]
         (438 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4506525 rhomboid protease 1 [Homo sapiens]                         905   0.0  
gi|21264326 rhomboid protease 3 [Homo sapiens]                        441   e-124
gi|54144654 rhomboid protease 2 [Homo sapiens]                        187   2e-47
gi|93352558 rhomboid, veinlet-like 6 isoform 2 [Homo sapiens]          43   5e-04
gi|93352556 rhomboid, veinlet-like 6 isoform 1 [Homo sapiens]          43   5e-04
gi|190341097 rhomboid family 1 [Homo sapiens]                          43   5e-04
gi|239757942 PREDICTED: hypothetical protein XP_002346387 [Homo ...    35   0.18 
gi|239747120 PREDICTED: hypothetical protein XP_002343918 [Homo ...    33   0.51 
gi|239747111 PREDICTED: hypothetical protein XP_002343913 [Homo ...    33   0.51 
gi|21618327 forkhead box I1 isoform a [Homo sapiens]                   33   0.51 
gi|21618329 forkhead box I1 isoform b [Homo sapiens]                   33   0.51 
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]        33   0.51 
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    33   0.67 
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    33   0.67 
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    33   0.67 
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    33   0.67 
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    33   0.67 
gi|238859653 pleckstrin homology domain containing family A memb...    32   1.5  
gi|10864037 myosin light chain 2a [Homo sapiens]                       32   1.5  
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             31   1.9  
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    31   1.9  
gi|153281158 dual specificity phosphatase 8 [Homo sapiens]             31   1.9  
gi|40353727 synaptopodin isoform A [Homo sapiens]                      31   2.5  
gi|4506857 chemokine (C-X3-C motif) ligand 1 [Homo sapiens]            30   3.3  
gi|7706577 PSMC3 interacting protein isoform 2 [Homo sapiens]          30   3.3  
gi|32261320 PSMC3 interacting protein isoform 1 [Homo sapiens]         30   3.3  
gi|194097352 actinin, alpha 1 isoform c [Homo sapiens]                 30   3.3  
gi|144922631 tigger transposable element derived 5 [Homo sapiens]      30   3.3  
gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo sa...    30   4.3  
gi|119943102 CREB binding protein isoform b [Homo sapiens]             30   4.3  

>gi|4506525 rhomboid protease 1 [Homo sapiens]
          Length = 438

 Score =  905 bits (2340), Expect = 0.0
 Identities = 438/438 (100%), Positives = 438/438 (100%)

Query: 1   MGRVEDGGTTEELEDWDPGTSALPAPGIKQGPREQTGTGPLSQKCWEPEPDAPSQPGPAL 60
           MGRVEDGGTTEELEDWDPGTSALPAPGIKQGPREQTGTGPLSQKCWEPEPDAPSQPGPAL
Sbjct: 1   MGRVEDGGTTEELEDWDPGTSALPAPGIKQGPREQTGTGPLSQKCWEPEPDAPSQPGPAL 60

Query: 61  WSRGRARTQALAGGSSLQQLDPENTGFIGADTFTGLVHSHELPLDPAKLDMLVALAQSNE 120
           WSRGRARTQALAGGSSLQQLDPENTGFIGADTFTGLVHSHELPLDPAKLDMLVALAQSNE
Sbjct: 61  WSRGRARTQALAGGSSLQQLDPENTGFIGADTFTGLVHSHELPLDPAKLDMLVALAQSNE 120

Query: 121 QGQVCYQELVDLISSKRSSSFKRAIANGQRALPRDGPLDEPGLGVYKRFVRYVAYEILPC 180
           QGQVCYQELVDLISSKRSSSFKRAIANGQRALPRDGPLDEPGLGVYKRFVRYVAYEILPC
Sbjct: 121 QGQVCYQELVDLISSKRSSSFKRAIANGQRALPRDGPLDEPGLGVYKRFVRYVAYEILPC 180

Query: 181 EVDRRWYFYRHRSCPPPVFMASVTLAQIIVFLCYGARLNKWVLQTYHPEYMKSPLVYHPG 240
           EVDRRWYFYRHRSCPPPVFMASVTLAQIIVFLCYGARLNKWVLQTYHPEYMKSPLVYHPG
Sbjct: 181 EVDRRWYFYRHRSCPPPVFMASVTLAQIIVFLCYGARLNKWVLQTYHPEYMKSPLVYHPG 240

Query: 241 HRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGLLRISLLYLAGVLAGSLTVS 300
           HRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGLLRISLLYLAGVLAGSLTVS
Sbjct: 241 HRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGLLRISLLYLAGVLAGSLTVS 300

Query: 301 ITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLR 360
           ITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLR
Sbjct: 301 ITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLR 360

Query: 361 FSPPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAV 420
           FSPPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAV
Sbjct: 361 FSPPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAV 420

Query: 421 FWNVFAYDLLGAHIPPPP 438
           FWNVFAYDLLGAHIPPPP
Sbjct: 421 FWNVFAYDLLGAHIPPPP 438


>gi|21264326 rhomboid protease 3 [Homo sapiens]
          Length = 404

 Score =  441 bits (1135), Expect = e-124
 Identities = 205/360 (56%), Positives = 265/360 (73%)

Query: 79  QLDPENTGFIGADTFTGLVHSHELPLDPAKLDMLVALAQSNEQGQVCYQELVDLISSKRS 138
           Q DP NTG+I    F  L+ SH   LDP K ++L+ALA S+  GQ+ YQ+ V L+S+KRS
Sbjct: 45  QFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDFVSLMSNKRS 104

Query: 139 SSFKRAIANGQRALPRDGPLDEPGLGVYKRFVRYVAYEILPCEVDRRWYFYRHRSCPPPV 198
           +SF++AI  G R L     L+E GL + +R +R+VAYE LP E+DR+WY+  +  CPPP 
Sbjct: 105 NSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETLPREIDRKWYYDSYTCCPPPW 164

Query: 199 FMASVTLAQIIVFLCYGARLNKWVLQTYHPEYMKSPLVYHPGHRARAWRFLTYMFMHVGL 258
           FM +VTL ++  FL  G  L ++VLQ  HP Y+K+ LVYHP  RA+ WR+LTY+FMH G+
Sbjct: 165 FMITVTLLEVAFFLYNGVSLGQFVLQVTHPRYLKNSLVYHPQLRAQVWRYLTYIFMHAGI 224

Query: 259 EQLGFNALLQLMIGVPLEMVHGLLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYAL 318
           E LG N +LQL++GVPLEMVHG  RI L+Y+AGV+AGSL VS+ DM APVVG SGGVYAL
Sbjct: 225 EHLGLNVVLQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYAL 284

Query: 319 CSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLRFSPPLPASGPQPSFMAHL 378
            SAHLAN+VMNW+GM+C +KLLRM +AL+CMS E GRAVWLRF P      P PSF+AHL
Sbjct: 285 VSAHLANIVMNWSGMKCQFKLLRMAVALICMSMEFGRAVWLRFHPSAYPPCPHPSFVAHL 344

Query: 379 AGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAVFWNVFAYDLLGAHIPPPP 438
            G  VG+++G+ +LR+YE+RL+DQ  WW+ +  Y  F+LFAVFWN+FAY LL   +PPPP
Sbjct: 345 GGVAVGITLGVVVLRNYEQRLQDQSLWWIFVAMYTVFVLFAVFWNIFAYTLLDLKLPPPP 404


>gi|54144654 rhomboid protease 2 [Homo sapiens]
          Length = 303

 Score =  187 bits (475), Expect = 2e-47
 Identities = 101/261 (38%), Positives = 159/261 (60%), Gaps = 7/261 (2%)

Query: 167 KRFVRYVAYEILPCEVDRRWYFYRHRSCPPPVFMASVTLAQIIVFLCYGA--RLNKWVLQ 224
           K+  R V+  +LP E  R  Y  R    PPPVF+ S++LA++ VF+ Y       +W+  
Sbjct: 43  KKVHRIVSKWMLP-EKSRGTYLERANCFPPPVFIISISLAELAVFIYYAVWKPQKQWI-- 99

Query: 225 TYHPEYMKSPLVYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGLLRI 284
           T     ++SP +Y P  R  AWRF++YM +H G++ +  N  +QL++G+PLEMVH  LR+
Sbjct: 100 TLDTGILESPFIYSPEKREEAWRFISYMLVHAGVQHILGNLCMQLVLGIPLEMVHKGLRV 159

Query: 285 SLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVL 344
            L+YLAGV+AGSL  SI D    +VG SGGVYAL   +  NV++N+  M   + + R+++
Sbjct: 160 GLVYLAGVIAGSLASSIFDPLRYLVGASGGVYALMGGYFMNVLVNFQEMIPAFGIFRLLI 219

Query: 345 ALVCMSSEVGRAVWLRFSPPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCG 404
            ++ +  ++G A++ RF   +P  G   SF AH+AG   G+S+G T+   +++ L     
Sbjct: 220 IILIIVLDMGFALYRRFF--VPEDGSPVSFAAHIAGGFAGMSIGYTVFSCFDKALLKDPR 277

Query: 405 WWVVLLAYGTFLLFAVFWNVF 425
           +W+ + AY   +LFAVF+N+F
Sbjct: 278 FWIAIAAYLACVLFAVFFNIF 298


>gi|93352558 rhomboid, veinlet-like 6 isoform 2 [Homo sapiens]
          Length = 827

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 37/181 (20%), Positives = 72/181 (39%), Gaps = 17/181 (9%)

Query: 246 WRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGLLRISLLYLAGVLAGSLTVSITDMR 305
           +R    +F+H G+     + + Q+ I   LE + G  RI+++++   + G+L  +I    
Sbjct: 626 YRLWLSLFLHAGVVHCLVSVVFQMTILRDLEKLAGWHRIAIIFILSGITGNLASAIFLPY 685

Query: 306 APVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLRFSPPL 365
              VG +G  + L +     +  +W  +  P+K    + A+V      G   W+      
Sbjct: 686 RAEVGPAGSQFGLLACLFVELFQSWPLLERPWKAFLNLSAIVLFLFICGLLPWI------ 739

Query: 366 PASGPQPSFMAHLAGAVVGVSMGLTILR----SYEERLRDQCGWWVVLLAYGTFLLFAVF 421
                    +AH+ G + G+ +    L        ++ R +    V LLA+       V 
Sbjct: 740 -------DNIAHIFGFLSGLLLAFAFLPYITFGTSDKYRKRALILVSLLAFAGLFAALVL 792

Query: 422 W 422
           W
Sbjct: 793 W 793


>gi|93352556 rhomboid, veinlet-like 6 isoform 1 [Homo sapiens]
          Length = 856

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 37/181 (20%), Positives = 72/181 (39%), Gaps = 17/181 (9%)

Query: 246 WRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGLLRISLLYLAGVLAGSLTVSITDMR 305
           +R    +F+H G+     + + Q+ I   LE + G  RI+++++   + G+L  +I    
Sbjct: 655 YRLWLSLFLHAGVVHCLVSVVFQMTILRDLEKLAGWHRIAIIFILSGITGNLASAIFLPY 714

Query: 306 APVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLRFSPPL 365
              VG +G  + L +     +  +W  +  P+K    + A+V      G   W+      
Sbjct: 715 RAEVGPAGSQFGLLACLFVELFQSWPLLERPWKAFLNLSAIVLFLFICGLLPWI------ 768

Query: 366 PASGPQPSFMAHLAGAVVGVSMGLTILR----SYEERLRDQCGWWVVLLAYGTFLLFAVF 421
                    +AH+ G + G+ +    L        ++ R +    V LLA+       V 
Sbjct: 769 -------DNIAHIFGFLSGLLLAFAFLPYITFGTSDKYRKRALILVSLLAFAGLFAALVL 821

Query: 422 W 422
           W
Sbjct: 822 W 822


>gi|190341097 rhomboid family 1 [Homo sapiens]
          Length = 855

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 30/147 (20%), Positives = 61/147 (41%), Gaps = 13/147 (8%)

Query: 246 WRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGLLRISLLYLAGVLAGSLTVSITDMR 305
           +R    +F+H G+     +   Q+ +   LE + G  RI+++YL   + G+L  +I    
Sbjct: 654 YRLWLSLFLHAGILHCLVSICFQMTVLRDLEKLAGWHRIAIIYLLSGVTGNLASAIFLPY 713

Query: 306 APVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLRFSPPL 365
              VG +G  + + +     +  +W  +  P++    +LA+V      G   W+      
Sbjct: 714 RAEVGPAGSQFGILACLFVELFQSWQILARPWRAFFKLLAVVLFLFTFGLLPWI------ 767

Query: 366 PASGPQPSFMAHLAGAVVGVSMGLTIL 392
                     AH++G + G+ +    L
Sbjct: 768 -------DNFAHISGFISGLFLSFAFL 787


>gi|239757942 PREDICTED: hypothetical protein XP_002346387 [Homo
           sapiens]
          Length = 239

 Score = 34.7 bits (78), Expect = 0.18
 Identities = 31/95 (32%), Positives = 38/95 (40%), Gaps = 18/95 (18%)

Query: 1   MGRVEDGGTTEELEDWDPGTSALPAPGIKQGPREQTGTGPLSQKCWEPEP---------- 50
           +GRV         E    G +A+P P  + G     G GPL    W P P          
Sbjct: 55  VGRVASRARARTWEGGKEGHAAVPQPATRSGRLGVWG-GPLRHS-WAPRPRQASQTRGGG 112

Query: 51  DAPSQPGPALWSRGRARTQALA------GGSSLQQ 79
             PS PGPA    GR+R++  A      GGS L Q
Sbjct: 113 GGPSLPGPAGRPSGRSRSRVGARGRLPSGGSHLPQ 147


>gi|239747120 PREDICTED: hypothetical protein XP_002343918 [Homo
           sapiens]
          Length = 139

 Score = 33.1 bits (74), Expect = 0.51
 Identities = 30/97 (30%), Positives = 37/97 (38%), Gaps = 16/97 (16%)

Query: 10  TEELEDWDPGTSALPAPGIKQGPREQTGTGPLSQKCWEPEPDAPSQPGPALWSRGRARTQ 69
           T+ L  W       PAP I     +    GP     W   P+ P+  GP LW +   RTQ
Sbjct: 18  TQPLAPWTMAAED-PAPRIL----DYGSRGPSLPASWTKAPEDPAPSGPGLWQQ---RTQ 69

Query: 70  ALAGGSSLQQLDPENTGFIGADTFTGLVHSHELPLDP 106
            LA  +   + DP       A    GL H    PL P
Sbjct: 70  PLASWTMAPE-DP-------ASLRHGLWHQRTQPLAP 98


>gi|239747111 PREDICTED: hypothetical protein XP_002343913 [Homo
           sapiens]
          Length = 139

 Score = 33.1 bits (74), Expect = 0.51
 Identities = 30/97 (30%), Positives = 37/97 (38%), Gaps = 16/97 (16%)

Query: 10  TEELEDWDPGTSALPAPGIKQGPREQTGTGPLSQKCWEPEPDAPSQPGPALWSRGRARTQ 69
           T+ L  W       PAP I     +    GP     W   P+ P+  GP LW +   RTQ
Sbjct: 18  TQPLAPWTMAAED-PAPRIL----DYGSRGPSLPASWTKAPEDPAPSGPGLWQQ---RTQ 69

Query: 70  ALAGGSSLQQLDPENTGFIGADTFTGLVHSHELPLDP 106
            LA  +   + DP       A    GL H    PL P
Sbjct: 70  PLASWTMAPE-DP-------ASLRHGLWHQRTQPLAP 98


>gi|21618327 forkhead box I1 isoform a [Homo sapiens]
          Length = 378

 Score = 33.1 bits (74), Expect = 0.51
 Identities = 20/84 (23%), Positives = 34/84 (40%), Gaps = 3/84 (3%)

Query: 18  PGTSALPAPGIKQGPREQTGTGPLSQKCWEPEPDAPSQPGPALWSRGRARTQALAGGSSL 77
           P +  L  PG+   P ++TG   L+   + P  +  +  G   W+          GGS L
Sbjct: 294 PTSHPLVTPGLSPEPSDKTGQNSLTFNSFSPLTNLSNHSGGGDWANPMPTNMLSYGGSVL 353

Query: 78  QQLDPENTGFIGADTFTGLVHSHE 101
            Q  P    F  +   +G+++  E
Sbjct: 354 SQFSPH---FYNSVNTSGVLYPRE 374


>gi|21618329 forkhead box I1 isoform b [Homo sapiens]
          Length = 283

 Score = 33.1 bits (74), Expect = 0.51
 Identities = 20/84 (23%), Positives = 34/84 (40%), Gaps = 3/84 (3%)

Query: 18  PGTSALPAPGIKQGPREQTGTGPLSQKCWEPEPDAPSQPGPALWSRGRARTQALAGGSSL 77
           P +  L  PG+   P ++TG   L+   + P  +  +  G   W+          GGS L
Sbjct: 199 PTSHPLVTPGLSPEPSDKTGQNSLTFNSFSPLTNLSNHSGGGDWANPMPTNMLSYGGSVL 258

Query: 78  QQLDPENTGFIGADTFTGLVHSHE 101
            Q  P    F  +   +G+++  E
Sbjct: 259 SQFSPH---FYNSVNTSGVLYPRE 279


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score = 33.1 bits (74), Expect = 0.51
 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 4/56 (7%)

Query: 7    GGTTEELEDWDPGTSALPAPGIKQGPREQTG----TGPLSQKCWEPEPDAPSQPGP 58
            G   E+ E   PG+  LP P    GPR + G    +G    + ++ +P  P  PGP
Sbjct: 1111 GSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGP 1166


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 32.7 bits (73), Expect = 0.67
 Identities = 19/42 (45%), Positives = 20/42 (47%), Gaps = 4/42 (9%)

Query: 18   PGTSALPAPGIKQGPREQTG-TGPLSQKCWEPEPDAPSQPGP 58
            PG   LP P   QGP+   G TGP  QK     P  P  PGP
Sbjct: 1512 PGPPGLPGP---QGPKGNKGSTGPAGQKGDSGLPGPPGSPGP 1550


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 32.7 bits (73), Expect = 0.67
 Identities = 19/42 (45%), Positives = 20/42 (47%), Gaps = 4/42 (9%)

Query: 18   PGTSALPAPGIKQGPREQTG-TGPLSQKCWEPEPDAPSQPGP 58
            PG   LP P   QGP+   G TGP  QK     P  P  PGP
Sbjct: 1461 PGPPGLPGP---QGPKGNKGSTGPAGQKGDSGLPGPPGSPGP 1499


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 32.7 bits (73), Expect = 0.67
 Identities = 19/42 (45%), Positives = 20/42 (47%), Gaps = 4/42 (9%)

Query: 18   PGTSALPAPGIKQGPREQTG-TGPLSQKCWEPEPDAPSQPGP 58
            PG   LP P   QGP+   G TGP  QK     P  P  PGP
Sbjct: 1500 PGPPGLPGP---QGPKGNKGSTGPAGQKGDSGLPGPPGSPGP 1538


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score = 32.7 bits (73), Expect = 0.67
 Identities = 22/88 (25%), Positives = 36/88 (40%), Gaps = 8/88 (9%)

Query: 19   GTSALPAPGIKQGPREQTG-TGPLSQKCWEPEPDAPSQPGPALWSRGRARTQALAGGSSL 77
            G + +P P    GPR ++G TGP         P  P  PGP +         +   G   
Sbjct: 1176 GANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGI-------DMSAFAGLGP 1228

Query: 78   QQLDPENTGFIGADTFTGLVHSHELPLD 105
            ++  P+   ++ AD   G +  H+  +D
Sbjct: 1229 REKGPDPLQYMRADQAAGGLRQHDAEVD 1256


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score = 32.7 bits (73), Expect = 0.67
 Identities = 22/88 (25%), Positives = 36/88 (40%), Gaps = 8/88 (9%)

Query: 19   GTSALPAPGIKQGPREQTG-TGPLSQKCWEPEPDAPSQPGPALWSRGRARTQALAGGSSL 77
            G + +P P    GPR ++G TGP         P  P  PGP +         +   G   
Sbjct: 1107 GANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGI-------DMSAFAGLGP 1159

Query: 78   QQLDPENTGFIGADTFTGLVHSHELPLD 105
            ++  P+   ++ AD   G +  H+  +D
Sbjct: 1160 REKGPDPLQYMRADQAAGGLRQHDAEVD 1187


>gi|238859653 pleckstrin homology domain containing family A member
           4 isoform 2 [Homo sapiens]
          Length = 583

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 20/51 (39%), Positives = 25/51 (49%), Gaps = 5/51 (9%)

Query: 15  DWDPGTSALPAPGI-KQGPREQTGTG--PLSQKCWEPEPDAPSQPGPALWS 62
           DW P    L  P   ++GP  + G G  P S + W  EP   +QPGP L S
Sbjct: 283 DWGPQRQTLSRPPTPRRGPPSEAGGGKPPRSPQHWSQEPR--TQPGPPLES 331


>gi|10864037 myosin light chain 2a [Homo sapiens]
          Length = 175

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 15/60 (25%), Positives = 29/60 (48%)

Query: 75  SSLQQLDPENTGFIGADTFTGLVHSHELPLDPAKLDMLVALAQSNEQGQVCYQELVDLIS 134
           S+ +  DP   G +  D F  L+ +      PA+++ + AL   +  G + Y+ L  +I+
Sbjct: 109 SAFRMFDPSGKGVVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIIT 168


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 31.2 bits (69), Expect = 1.9
 Identities = 15/56 (26%), Positives = 20/56 (35%), Gaps = 4/56 (7%)

Query: 8    GTTEELEDWDPGTSALPAPGIK----QGPREQTGTGPLSQKCWEPEPDAPSQPGPA 59
            G T     W P   +   PG          + +G  P     W P P +P  PGP+
Sbjct: 1523 GATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPS 1578


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 31.2 bits (69), Expect = 1.9
 Identities = 36/124 (29%), Positives = 49/124 (39%), Gaps = 20/124 (16%)

Query: 4    VEDGGTTEEL-EDWDP--GTSALPAPGIKQGPREQTGTGPLSQKCWEPEPDAPS------ 54
            VE+ GT EE   D  P     ALP+ G  +   E    GP  Q+  E EP AP       
Sbjct: 1009 VEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEE 1068

Query: 55   --------QPGPALWSRGRARTQALAGGSSLQQLDPENTGFIGADTFTGLVHSHELPLDP 106
                    QP P   +     T+  A   +LQ+ + ++T  + AD F       E P  P
Sbjct: 1069 TEDGSDKVQPPPETPAEEEMETETEA--EALQEKEQDDTAAMLAD-FIDCPPDDEKPPPP 1125

Query: 107  AKLD 110
             + D
Sbjct: 1126 TEPD 1129


>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
          Length = 625

 Score = 31.2 bits (69), Expect = 1.9
 Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 6/40 (15%)

Query: 19  GTSALPAPGIKQGPREQTGTGPLSQKCWEPEPDAPSQPGP 58
           G SAL APG+  GP +  G G      W P  D+P  P P
Sbjct: 487 GLSALSAPGLP-GPGQPAGPG-----AWAPPLDSPGTPSP 520


>gi|40353727 synaptopodin isoform A [Homo sapiens]
          Length = 903

 Score = 30.8 bits (68), Expect = 2.5
 Identities = 16/46 (34%), Positives = 21/46 (45%), Gaps = 2/46 (4%)

Query: 18  PGTSALPAPGIKQGPREQTGTGPLSQKCWEPEPDAPSQPGPALWSR 63
           PG++A+P       PR     GP S  C  P    P+ P P L+ R
Sbjct: 810 PGSAAVPGAAFAPIPRSPLPAGPSS--CTSPRSPLPAPPRPFLYRR 853


>gi|4506857 chemokine (C-X3-C motif) ligand 1 [Homo sapiens]
          Length = 397

 Score = 30.4 bits (67), Expect = 3.3
 Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 13/67 (19%)

Query: 8   GTTEELEDWDPGTSALPAPGIKQGPREQTGTGPLSQKCWEPEP---------DAPSQPGP 58
           GT+ EL     G+S    P     P+ Q G GP+  + +   P          AP QPGP
Sbjct: 152 GTSPELPTGVTGSSGTRLPPT---PKAQDG-GPVGTELFRVPPVSTAATWQSSAPHQPGP 207

Query: 59  ALWSRGR 65
           +LW+  +
Sbjct: 208 SLWAEAK 214


>gi|7706577 PSMC3 interacting protein isoform 2 [Homo sapiens]
          Length = 217

 Score = 30.4 bits (67), Expect = 3.3
 Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 4/63 (6%)

Query: 62  SRGRARTQALAGGSSLQQLDPENTGFIGADTFTGLVHSHELPLDPAKLDMLVALAQSNEQ 121
           S+GRA   A A G  L+ L  +N  +   D F  L   H L     K  ++  L Q  +Q
Sbjct: 2   SKGRAEAAAGAAGILLRYLQEQNRPYSSQDVFGNLQREHGL----GKAVVVKTLEQLAQQ 57

Query: 122 GQV 124
           G++
Sbjct: 58  GKI 60


>gi|32261320 PSMC3 interacting protein isoform 1 [Homo sapiens]
          Length = 205

 Score = 30.4 bits (67), Expect = 3.3
 Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 4/63 (6%)

Query: 62  SRGRARTQALAGGSSLQQLDPENTGFIGADTFTGLVHSHELPLDPAKLDMLVALAQSNEQ 121
           S+GRA   A A G  L+ L  +N  +   D F  L   H L     K  ++  L Q  +Q
Sbjct: 2   SKGRAEAAAGAAGILLRYLQEQNRPYSSQDVFGNLQREHGL----GKAVVVKTLEQLAQQ 57

Query: 122 GQV 124
           G++
Sbjct: 58  GKI 60


>gi|194097352 actinin, alpha 1 isoform c [Homo sapiens]
          Length = 887

 Score = 30.4 bits (67), Expect = 3.3
 Identities = 16/79 (20%), Positives = 36/79 (45%)

Query: 62  SRGRARTQALAGGSSLQQLDPENTGFIGADTFTGLVHSHELPLDPAKLDMLVALAQSNEQ 121
           ++G ++ Q     +S    D + TG +  D F   + S    +  A+   ++++   N  
Sbjct: 740 AKGISQEQMNEFRASFNHFDRKKTGMMDTDDFRACLISMGYNMGEAEFARIMSIVDPNRL 799

Query: 122 GQVCYQELVDLISSKRSSS 140
           G V +Q  +D +S + + +
Sbjct: 800 GVVTFQAFIDFMSRETADT 818


>gi|144922631 tigger transposable element derived 5 [Homo sapiens]
          Length = 593

 Score = 30.4 bits (67), Expect = 3.3
 Identities = 14/40 (35%), Positives = 20/40 (50%), Gaps = 2/40 (5%)

Query: 18  PGTSALPAPGIKQGPREQTGTGPLSQKCWEPEPDAPSQPG 57
           P  S  P P +K+ P   +G GPL  +   P P  P++ G
Sbjct: 144 PAPSPAPGPPVKEEPALPSGAGPLPDRA--PAPPPPAEGG 181


>gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo
           sapiens]
          Length = 756

 Score = 30.0 bits (66), Expect = 4.3
 Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 9/57 (15%)

Query: 2   GRVEDGGTTEELEDWDPGTSALPAPGIKQGPREQTGTGPLSQKCWEPEPDAPSQPGP 58
           G   DGG       W  G    PAPG++ GPR+   + P  +     +  +P  PGP
Sbjct: 61  GAAADGGAR-----WSAG----PAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGP 108


>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 30.0 bits (66), Expect = 4.3
 Identities = 33/132 (25%), Positives = 47/132 (35%), Gaps = 18/132 (13%)

Query: 2   GRVEDGGTTEELEDWDPGTSALPAPGIKQGPREQT--------GTGPLSQKC----WEPE 49
           G+V        L    P  S LP P + Q P   T        G   L          P+
Sbjct: 784 GQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQ 843

Query: 50  PDAPSQPGPALWSRGRARTQALAGGSSLQQLDPENTGFIGADTFTGLVHSHELPLDPAKL 109
           P AP+QP   + S G+  T     GS       ++T  + A     +    + P+ P   
Sbjct: 844 PAAPTQPSTPVSSSGQTPTP--TPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPS- 900

Query: 110 DMLVALAQSNEQ 121
              VA  QS++Q
Sbjct: 901 ---VATPQSSQQ 909


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.139    0.449 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,819,451
Number of Sequences: 37866
Number of extensions: 982561
Number of successful extensions: 3555
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 3477
Number of HSP's gapped (non-prelim): 128
length of query: 438
length of database: 18,247,518
effective HSP length: 105
effective length of query: 333
effective length of database: 14,271,588
effective search space: 4752438804
effective search space used: 4752438804
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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