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Search of human proteins with 4503177
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503177 testis expressed 28 [Homo sapiens]
(410 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503177 testis expressed 28 [Homo sapiens] 820 0.0
gi|190014612 transmembrane and coiled-coil domain family 1 isofo... 135 9e-32
gi|190014610 transmembrane and coiled-coil domain family 1 isofo... 135 9e-32
gi|39930343 transmembrane and coiled-coil domain family 1 isofor... 122 4e-28
gi|54792740 transmembrane and coiled-coil domain family 2 [Homo ... 112 5e-25
gi|188497714 transmembrane and coiled-coil domain family 3 [Homo... 84 2e-16
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 44 3e-04
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 44 3e-04
gi|153945715 myosin VC [Homo sapiens] 42 0.001
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 42 0.001
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 41 0.002
gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 40 0.003
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 39 0.007
gi|62821790 leucine zipper protein 2 [Homo sapiens] 39 0.009
gi|81295809 pericentrin [Homo sapiens] 39 0.011
gi|8923720 zinc finger, C4H2 domain containing [Homo sapiens] 39 0.011
gi|21450705 leucine rich repeat containing 45 [Homo sapiens] 39 0.011
gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo sa... 38 0.015
gi|75750468 spectrin domain with coiled-coils 1 NSP5a3a [Homo sa... 38 0.015
gi|75750472 spectrin domain with coiled-coils 1 NSP5b3b [Homo sa... 38 0.015
gi|75750466 spectrin domain with coiled-coils 1 NSP5b3a [Homo sa... 38 0.015
gi|71061468 centromere protein E [Homo sapiens] 38 0.015
gi|4505257 moesin [Homo sapiens] 38 0.019
gi|32698688 citron [Homo sapiens] 37 0.025
gi|82775371 coiled-coil domain containing 93 [Homo sapiens] 37 0.025
gi|134152674 rabaptin, RAB GTPase binding effector protein 1 iso... 37 0.025
gi|50658082 centrosomal protein 70 kDa [Homo sapiens] 37 0.025
gi|45439327 periplakin [Homo sapiens] 37 0.025
gi|31377798 rabaptin, RAB GTPase binding effector protein 1 isof... 37 0.025
gi|14249254 EF-hand calcium binding domain 4B isoform c [Homo sa... 37 0.032
>gi|4503177 testis expressed 28 [Homo sapiens]
Length = 410
Score = 820 bits (2117), Expect = 0.0
Identities = 410/410 (100%), Positives = 410/410 (100%)
Query: 1 MVLKAEHTRSPSATLPSNVPSCRSLSSSEDGPSGPSSLADGGLAHNLQDSVRHRILYLSE 60
MVLKAEHTRSPSATLPSNVPSCRSLSSSEDGPSGPSSLADGGLAHNLQDSVRHRILYLSE
Sbjct: 1 MVLKAEHTRSPSATLPSNVPSCRSLSSSEDGPSGPSSLADGGLAHNLQDSVRHRILYLSE 60
Query: 61 QLRVEKASRDGNTVSYLKLVSKADRHQVPHIQQAFEKVNQRASATIAQIEHRLHQCHQQL 120
QLRVEKASRDGNTVSYLKLVSKADRHQVPHIQQAFEKVNQRASATIAQIEHRLHQCHQQL
Sbjct: 61 QLRVEKASRDGNTVSYLKLVSKADRHQVPHIQQAFEKVNQRASATIAQIEHRLHQCHQQL 120
Query: 121 QELEEGCRPEGLLLMAESDPANCEPPSEKALLSEPPEPGGEDGPVNLPHASRPFILESRF 180
QELEEGCRPEGLLLMAESDPANCEPPSEKALLSEPPEPGGEDGPVNLPHASRPFILESRF
Sbjct: 121 QELEEGCRPEGLLLMAESDPANCEPPSEKALLSEPPEPGGEDGPVNLPHASRPFILESRF 180
Query: 181 QSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDLQLLLES 240
QSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDLQLLLES
Sbjct: 181 QSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDLQLLLES 240
Query: 241 LQEEKCRQALMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKS 300
LQEEKCRQALMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKS
Sbjct: 241 LQEEKCRQALMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKS 300
Query: 301 RISKLEMLQQVTQLEAAEHLQSRPPQMLFKFLSPRLSLATVLLVFVSTLCACPSSLISSR 360
RISKLEMLQQVTQLEAAEHLQSRPPQMLFKFLSPRLSLATVLLVFVSTLCACPSSLISSR
Sbjct: 301 RISKLEMLQQVTQLEAAEHLQSRPPQMLFKFLSPRLSLATVLLVFVSTLCACPSSLISSR 360
Query: 361 LCTCTMLMLIGLGVLAWQRWRAIPATDWQEWVPSRCRLYSKDSGPPADGP 410
LCTCTMLMLIGLGVLAWQRWRAIPATDWQEWVPSRCRLYSKDSGPPADGP
Sbjct: 361 LCTCTMLMLIGLGVLAWQRWRAIPATDWQEWVPSRCRLYSKDSGPPADGP 410
>gi|190014612 transmembrane and coiled-coil domain family 1 isoform
c [Homo sapiens]
Length = 539
Score = 135 bits (339), Expect = 9e-32
Identities = 127/432 (29%), Positives = 197/432 (45%), Gaps = 82/432 (18%)
Query: 26 SSSEDGPSGPSSLADGGLAHNLQDSVRHRILYLSEQLRVEKASRDGNTVSYLKLVSKADR 85
+ S DG P +AH ++ +IL L+EQ+++ + +RD N YLKL + AD+
Sbjct: 104 TDSVDGTPDPQR-TKAAIAH-----LQQKILKLTEQIKIAQTARDDNVAEYLKLANSADK 157
Query: 86 HQVPHIQQAFEKVNQRASATIAQIEHRLHQCHQQLQELEEGCRP---------------- 129
Q I+Q FEK NQ+++ TI Q++ +L H++L+E+E+ P
Sbjct: 158 QQAARIKQVFEKKNQKSAQTILQLQKKLEHYHRKLREVEQNGIPRQPKDVFRDMHQGLKD 217
Query: 130 ---------EGLLLMAE---SDPANCEPPSEKALLSEPPEP--------GGEDGPVNL-- 167
EG++ + S + + A++S+P E G D NL
Sbjct: 218 VGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSADNIPNLKD 277
Query: 168 -------PHASRPFILESRFQSL----QQGTCLETEDVAQQQNLLLQKVKAELEEAKRFH 216
A + + S FQS + C + N + +K
Sbjct: 278 SLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGASSSKTNT 337
Query: 217 ISLQES-----YHSLKERSLTDLQL--LLESLQEEKCR------QALMEEQVN-GRLQGQ 262
+ +Q S H ++E T +L E+L+E R Q L EE+ RL+ Q
Sbjct: 338 LDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQ 397
Query: 263 L--------NEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKSRISKLEM---LQQV 311
L NEI NLK LA EE++AY SYERA++I E E ++RISK+E+ QQV
Sbjct: 398 LNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQV 457
Query: 312 TQLEAAEHLQSRPPQMLFKFLSPRLSLATVLLVFVSTLCACPSSLISSRLCTCTMLMLIG 371
QLE E+ +R +L K ++ L++ VLLVFVST+ C L+ +R T + L L+
Sbjct: 458 VQLEGLENATAR--NLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFSTLFLVV 515
Query: 372 LGVLAWQRWRAI 383
W+ W A+
Sbjct: 516 FIAFLWKHWDAL 527
>gi|190014610 transmembrane and coiled-coil domain family 1 isoform
a [Homo sapiens]
Length = 653
Score = 135 bits (339), Expect = 9e-32
Identities = 127/432 (29%), Positives = 197/432 (45%), Gaps = 82/432 (18%)
Query: 26 SSSEDGPSGPSSLADGGLAHNLQDSVRHRILYLSEQLRVEKASRDGNTVSYLKLVSKADR 85
+ S DG P +AH ++ +IL L+EQ+++ + +RD N YLKL + AD+
Sbjct: 218 TDSVDGTPDPQR-TKAAIAH-----LQQKILKLTEQIKIAQTARDDNVAEYLKLANSADK 271
Query: 86 HQVPHIQQAFEKVNQRASATIAQIEHRLHQCHQQLQELEEGCRP---------------- 129
Q I+Q FEK NQ+++ TI Q++ +L H++L+E+E+ P
Sbjct: 272 QQAARIKQVFEKKNQKSAQTILQLQKKLEHYHRKLREVEQNGIPRQPKDVFRDMHQGLKD 331
Query: 130 ---------EGLLLMAE---SDPANCEPPSEKALLSEPPEP--------GGEDGPVNL-- 167
EG++ + S + + A++S+P E G D NL
Sbjct: 332 VGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSADNIPNLKD 391
Query: 168 -------PHASRPFILESRFQSL----QQGTCLETEDVAQQQNLLLQKVKAELEEAKRFH 216
A + + S FQS + C + N + +K
Sbjct: 392 SLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGASSSKTNT 451
Query: 217 ISLQES-----YHSLKERSLTDLQL--LLESLQEEKCR------QALMEEQVN-GRLQGQ 262
+ +Q S H ++E T +L E+L+E R Q L EE+ RL+ Q
Sbjct: 452 LDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQ 511
Query: 263 L--------NEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKSRISKLEM---LQQV 311
L NEI NLK LA EE++AY SYERA++I E E ++RISK+E+ QQV
Sbjct: 512 LNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQV 571
Query: 312 TQLEAAEHLQSRPPQMLFKFLSPRLSLATVLLVFVSTLCACPSSLISSRLCTCTMLMLIG 371
QLE E+ +R +L K ++ L++ VLLVFVST+ C L+ +R T + L L+
Sbjct: 572 VQLEGLENATAR--NLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFSTLFLVV 629
Query: 372 LGVLAWQRWRAI 383
W+ W A+
Sbjct: 630 FIAFLWKHWDAL 641
>gi|39930343 transmembrane and coiled-coil domain family 1 isoform b
[Homo sapiens]
Length = 329
Score = 122 bits (307), Expect = 4e-28
Identities = 72/179 (40%), Positives = 108/179 (60%), Gaps = 5/179 (2%)
Query: 208 ELEEAKRFHISLQESYHSLKERSLTDLQLLLESLQEEKCRQALMEEQVNGRLQGQLNEIY 267
E++E + L+ES+ +LKE D L++++LQEE+ R +EEQ+N + NEI
Sbjct: 141 EIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEIL 200
Query: 268 NLKHNLACSEERMAYLSYERAKEIWEITETFKSRISKLEM---LQQVTQLEAAEHLQSRP 324
NLK LA EE++AY SYERA++I E E ++RISK+E+ QQV QLE E+ +R
Sbjct: 201 NLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLEGLENATAR- 259
Query: 325 PQMLFKFLSPRLSLATVLLVFVSTLCACPSSLISSRLCTCTMLMLIGLGVLAWQRWRAI 383
+L K ++ L++ VLLVFVST+ C L+ +R T + L L+ W+ W A+
Sbjct: 260 -NLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFSTLFLVVFIAFLWKHWDAL 317
>gi|54792740 transmembrane and coiled-coil domain family 2 [Homo
sapiens]
Length = 709
Score = 112 bits (281), Expect = 5e-25
Identities = 70/185 (37%), Positives = 107/185 (57%), Gaps = 5/185 (2%)
Query: 202 LQKVKAELEEAKRFHISLQESYHSLKERSLTDLQLLLESLQEEKCRQALMEEQVNGRLQG 261
L + EL E K L++S LK + D + + LQEE+ R +EEQ+N +
Sbjct: 516 LDALLEELREIKEGQSHLEDSMEDLKTQLQRDYTYMTQCLQEERYRYERLEEQLNDLTEL 575
Query: 262 QLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKSRISKLEM---LQQVTQLEAAE 318
NE+ NLK LA EE++AY SYERA++I E E+ +R++KLE+ QQV QLE E
Sbjct: 576 HQNEMTNLKQELASMEEKVAYQSYERARDIQEAVESCLTRVTKLELQQQQQQVVQLEGVE 635
Query: 319 HLQSRPPQMLFKFLSPRLSLATVLLVFVSTLCACPSSLISSRLCTCTMLMLIGLGVLAWQ 378
+ +R +L KF++ L+L VLLVFVST+ + L+ +RL + +L+ + L W+
Sbjct: 636 NANAR--ALLGKFINVILALMAVLLVFVSTIANFITPLMKTRLRITSTTLLVLVLFLLWK 693
Query: 379 RWRAI 383
W ++
Sbjct: 694 HWDSL 698
Score = 73.9 bits (180), Expect = 2e-13
Identities = 37/99 (37%), Positives = 59/99 (59%), Gaps = 3/99 (3%)
Query: 30 DGPSG---PSSLADGGLAHNLQDSVRHRILYLSEQLRVEKASRDGNTVSYLKLVSKADRH 86
DGP P D D + +IL ++EQ+++E+ +RD N YLKL + AD+
Sbjct: 268 DGPISLDVPDGAPDPQRTKAAIDHLHQKILKITEQIKIEQEARDDNVAEYLKLANNADKQ 327
Query: 87 QVPHIQQAFEKVNQRASATIAQIEHRLHQCHQQLQELEE 125
QV I+Q FEK NQ+++ TIAQ+ +L ++L+E+E+
Sbjct: 328 QVSRIKQVFEKKNQKSAQTIAQLHKKLEHYRRRLKEIEQ 366
>gi|188497714 transmembrane and coiled-coil domain family 3 [Homo
sapiens]
Length = 477
Score = 84.0 bits (206), Expect = 2e-16
Identities = 38/91 (41%), Positives = 63/91 (69%)
Query: 35 PSSLADGGLAHNLQDSVRHRILYLSEQLRVEKASRDGNTVSYLKLVSKADRHQVPHIQQA 94
P + D DS++ +IL ++EQ+++E+ SRDGN YLKLV+ AD+ Q I+Q
Sbjct: 55 PDGILDFHKVKLTADSLKQKILKVTEQIKIEQTSRDGNVAEYLKLVNNADKQQAGRIKQV 114
Query: 95 FEKVNQRASATIAQIEHRLHQCHQQLQELEE 125
FEK NQ+++ +IAQ++ +L Q H++L+E+E+
Sbjct: 115 FEKKNQKSAHSIAQLQKKLEQYHRKLREIEQ 145
Score = 82.4 bits (202), Expect = 7e-16
Identities = 55/179 (30%), Positives = 94/179 (52%), Gaps = 2/179 (1%)
Query: 202 LQKVKAELEEAKRFHISLQESYHSLKERSLTDLQLLLESLQEEKCRQALMEEQVNGRLQG 261
L + EL E K L E +LK + + + ++LQEE+ R +E+Q++
Sbjct: 287 LAVILEELREIKDTQAQLAEDIEALKVQFKREYGFISQTLQEERYRYERLEDQLHDLTDL 346
Query: 262 QLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKSRISKLEMLQQVTQLEAAEHLQ 321
+E NLK LA EE++AY +YER+++I E E+ ++RISKLE+ QQ Q + +
Sbjct: 347 HQHETANLKQELASIEEKVAYQAYERSRDIQEALESCQTRISKLELHQQEQQALQTDTVN 406
Query: 322 SRPPQMLFKFLSPRLSLATVLLVFVSTLCACPSSLISSRLCTCTMLMLIGLGVLAWQRW 380
++ +L + ++ L+ TV+LV VST+ S ++ SR + L + + W
Sbjct: 407 AK--VLLGRCINVILAFMTVILVCVSTIAKFVSPMMKSRCHILGTFFAVTLLAIFCKNW 463
>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 479
Score = 43.9 bits (102), Expect = 3e-04
Identities = 61/236 (25%), Positives = 102/236 (43%), Gaps = 37/236 (15%)
Query: 93 QAFEKVNQRASATIAQIEHRLHQCHQQLQELEEGCRPEGLLLMAESDPANCEPPSEKALL 152
Q +N+R + + E RLH+ ++L E EE + E + CE ++ L
Sbjct: 188 QMLSLLNRRQEERLREQEERLHEQEERLHEQEE--------RLCEQEERLCE---QEERL 236
Query: 153 SEPPEPGGEDGPVNLPHASRPFILESRFQSLQQGTCLETEDVAQQQNL-----LLQKVKA 207
E E E R E R ++ C + E + +Q+ L LL++V+
Sbjct: 237 REQEERLRE-------QEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEK 289
Query: 208 ELEEAKRFHISLQESYHSL--KERSLTDLQLLLESLQEEKCRQALMEEQVNGRLQGQLNE 265
LE+ +R QE L +ER L +++ LLE + + + L +++ L+ +L E
Sbjct: 290 LLEQERR-----QEEQERLLERERLLDEVEELLEQERLRQQDERLWQQETLRELE-RLRE 343
Query: 266 IYNLKHNLACSE-ERMAYLSYE-----RAKEIWEITETFKSRISKLEMLQQVTQLE 315
+ L+ E ERM L +E RA+ E S L++ QQV +LE
Sbjct: 344 LERLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELE 399
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 43.5 bits (101), Expect = 3e-04
Identities = 72/303 (23%), Positives = 116/303 (38%), Gaps = 62/303 (20%)
Query: 23 RSLSSSEDGPSGPSSLADGGLAHNL-QDSVRHRILYLSEQLRVEKASRDGNTVSYLKLVS 81
RSL++ E+ P GP + A L +DS L LS Q
Sbjct: 486 RSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQ-------------------- 525
Query: 82 KADRHQVPHIQQAFEKVNQRASATIAQIEHRLHQCHQQLQEL----EEGCRPEGLLLMAE 137
R Q P A EK ++ H Q +EL EE PE + ++
Sbjct: 526 ---REQAPSPPAACEKGKEQ---------------HSQAEELGPGQEEAEDPEEKVAVSP 567
Query: 138 SDPANCEPPSEKALLSEPPEPGGEDGPVNLPHASRPFILESRFQSLQQGTCLETEDVAQQ 197
+ P + E S +EP P P L A+ + E+ Q L+Q E ++
Sbjct: 568 TPPVSPEVRS-----TEPVAP-----PEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEK 617
Query: 198 QNLLLQKV-KAELEEAKRFHISLQESYHSLKERSLTDLQLLLESLQEEKCRQALMEEQVN 256
L +K+ + E EE R H ++S SL+ER L ++++EE+ R E Q
Sbjct: 618 MQQLREKLCQEEEEEILRLHQQKEQSLSSLRER-------LQKAIEEEEARMREEESQRL 670
Query: 257 GRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKSRISKLEMLQQV-TQLE 315
L+ Q+ + +E+ + E + E +ML+Q+ ++E
Sbjct: 671 SWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIE 730
Query: 316 AAE 318
A+E
Sbjct: 731 ASE 733
Score = 33.1 bits (74), Expect = 0.47
Identities = 56/241 (23%), Positives = 99/241 (41%), Gaps = 37/241 (15%)
Query: 91 IQQAFEKVNQRASATIAQIEHRLHQCHQQL----QELEEGCRPEGLLLMAESDPANCEPP 146
IQ+A +K + + Q+EHR+HQ + EL R + + E + +
Sbjct: 796 IQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMK 855
Query: 147 SE-KALLSEPPEPGGEDGPVNLPHASRPFILESRFQSLQQGTCLETEDVAQQQNLLLQKV 205
E + ++++ E + A L + LQ+ E E V Q+Q+ L+ +
Sbjct: 856 EEHQQVMAKAREQ--YEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDL 913
Query: 206 KAELEEAKRFHISLQESYHSLKERSLTDLQLLLES-LQEEKCRQALME--EQVNGRLQGQ 262
+ H +ER L DL+L LE+ ++ K R AL+E E+ R + Q
Sbjct: 914 RRR---------------HREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQ 958
Query: 263 LNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKSRISKLEMLQQVTQLEAAEHLQS 322
L ++ + ++A S E ++ E K L+ QQ+ E + LQ+
Sbjct: 959 LLDV----------QRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLR--EILDELQA 1006
Query: 323 R 323
R
Sbjct: 1007 R 1007
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 42.0 bits (97), Expect = 0.001
Identities = 37/148 (25%), Positives = 74/148 (50%), Gaps = 13/148 (8%)
Query: 193 DVAQQQNLLLQKVKAELEEAK-RFHISLQESYHSLKERSLTDLQLLLESLQEEKCRQALM 251
D +++ LQK +ELE K + + LQE LKE+ + L + +Q+E+ ++ L+
Sbjct: 952 DAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLL 1011
Query: 252 EEQVNGRLQGQLNEIYNLKHNL-ACSEERM--------AYLSYERAK-EIWEITETFK-- 299
E+ + Q +I +LK + A +E+M +++ + K E+ +++ K
Sbjct: 1012 EKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTI 1071
Query: 300 SRISKLEMLQQVTQLEAAEHLQSRPPQM 327
S K L Q +++ +H+QS+ +M
Sbjct: 1072 SEFEKEIELLQAQKIDVEKHVQSQKREM 1099
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 41.6 bits (96), Expect = 0.001
Identities = 68/303 (22%), Positives = 122/303 (40%), Gaps = 31/303 (10%)
Query: 32 PSGPSSLADGGLAHNLQDSVRHRILYLSEQLRVEKASRDGNTVSYLKLVSKAD----RHQ 87
P+GPS + LQD H L R +A + N + L L+++ R Q
Sbjct: 153 PAGPSKV------EQLQDETNHLRKELESVGRQLQAEVENNQM--LSLLNRRQEERLREQ 204
Query: 88 VPHIQQAFEKVNQRASATIAQIEHRLHQCHQQLQELEEG-CRPEGLLL-----MAESDPA 141
+++ E++ ++ Q E RL + ++L+E EE C E L + E +
Sbjct: 205 EERLREQEERLREQEERLCEQ-EERLREQEERLREQEERLCEQEERLREHEERLCEQEER 263
Query: 142 NCEPPS----EKALLSEPPEPGGEDGPVNLPHASRPFILESRFQSLQQGTCLETEDVAQQ 197
CE ++ L E E E R E R + ++ C + E + +Q
Sbjct: 264 LCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQ 323
Query: 198 QNLLLQKVKAE-----LEEAKRFHISLQESYHSLKERSLTDLQLLLESLQEEKCRQALME 252
+ L ++ K LEE ++ L++ ++ L + + LLE ++E ++ L +
Sbjct: 324 EERLCEQEKLPGQERLLEEVEKL---LEQERRQEEQERLLERERLLEEVEELLEQERLRQ 380
Query: 253 EQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKSRISKLEMLQQVT 312
+ Q L E+ L+ E L +RA+ E S L++ QQV
Sbjct: 381 QDERLWQQETLQELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVK 440
Query: 313 QLE 315
+L+
Sbjct: 441 ELK 443
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 41.2 bits (95), Expect = 0.002
Identities = 76/313 (24%), Positives = 136/313 (43%), Gaps = 41/313 (13%)
Query: 23 RSLSSSEDGPSGPSSLADGGLAHNLQDSVRHRILYLSEQLRVEKASRDGNTVSYLKLVSK 82
R LSS+ + SS AD +LQ+S++ I L EQL E +D K
Sbjct: 404 RYLSSANPNDNRTSSNAD----KSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIK 459
Query: 83 ADRHQVPHIQQAFEKVNQRAS--ATIAQIE-------HRLHQCHQQL-QELEEGCRPEGL 132
D+ +++ E+ NQR + +T++QIE HR+++ ++ QE E+ E
Sbjct: 460 LDK----IMKELDEEGNQRRNLESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENE 515
Query: 133 LLMAESDPANCEPPSEKALLSEPPEPGGEDGPVNLPHASRPFILES-RFQSLQQGTCLET 191
+ + + + S+ + L+ + L A+ ES L++ +
Sbjct: 516 VSTLKDQLEDLKKVSQNSQLANEKLSQLQK---QLEEANDLLRTESDTAVRLRKSHTEMS 572
Query: 192 EDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDLQLLLESLQEEKCRQALM 251
+ ++Q L+ + EL+E R + E+ S ++ LQ +LE+ + ++ + M
Sbjct: 573 KSISQ-----LESLNRELQERNR----ILENSKSQTDKDYYQLQAILEAERRDRGHDSEM 623
Query: 252 EEQVNGRLQGQLNEIYNLKHNLACSE----ERMAYLSY-ERAKEIWEITETFKSRISKLE 306
+ R+ E+ +LKHNL E E L++ E+ K EI + KL+
Sbjct: 624 IGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNY-----KLK 678
Query: 307 MLQQVTQLEAAEH 319
LQQ + E EH
Sbjct: 679 SLQQRLEQEVNEH 691
>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
a [Homo sapiens]
Length = 1007
Score = 40.4 bits (93), Expect = 0.003
Identities = 33/140 (23%), Positives = 75/140 (53%), Gaps = 6/140 (4%)
Query: 177 ESRFQSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDLQL 236
E F S +Q + + + ++ +L Q+++ EE + + SL++ Y S+ E+ +DL L
Sbjct: 69 EVEFGSSKQCHLRQLQQLKKKLLVLQQELEFHTEELQTSYYSLRQ-YQSILEKQTSDLVL 127
Query: 237 LLESLQEEKCRQALMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITE 296
L + ++ L EE++ + +++ + LA + +++A S ER+ ++ +
Sbjct: 128 LHHHCKLKEDEVILYEEEMGNHNENTGEKLHLAQEQLALAGDKIA--SLERSLNLYR--D 183
Query: 297 TFKSRISKLEMLQ-QVTQLE 315
++S +S +E+L+ QV L+
Sbjct: 184 KYQSSLSNIELLECQVKMLQ 203
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 39.3 bits (90), Expect = 0.007
Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 24/168 (14%)
Query: 182 SLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSL------KERSLTDLQ 235
++Q L+ E L QK + + E+ +R + +E L KER L +L+
Sbjct: 306 AIQMAIRLQAEGKTSLHKDLKQKRREQREQRERRRAAKEEELLRLQQLQEEKERKLQELE 365
Query: 236 LLLES-------LQEEKCRQALMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERA 288
LL E+ LQEE+ R+ ++ L+GQL E + A + M E A
Sbjct: 366 LLQEAQRQAERLLQEEEERRRSQHRELQQALEGQLREAEQAR---ASMQAEMELKEEEAA 422
Query: 289 KEIWEITETFKSRISKLEMLQQVTQLEAAEHLQSRPPQMLFKFLSPRL 336
++ + RI +LE +QQ Q +++R + + RL
Sbjct: 423 RQ--------RQRIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRL 462
Score = 29.6 bits (65), Expect = 5.2
Identities = 34/168 (20%), Positives = 68/168 (40%), Gaps = 19/168 (11%)
Query: 93 QAFEKVNQRASATIAQIEHRLHQCHQQLQELEEGCRPEGLLLMAESDPANCEPPSEKALL 152
+ ++ ++A + + E R H++LQ+ EG + E++ A +E L
Sbjct: 365 ELLQEAQRQAERLLQEEEERRRSQHRELQQALEG-------QLREAEQARASMQAEMELK 417
Query: 153 SEPPEPGGEDGPVNLPHASRPFILESRFQSLQQGTCLETEDVAQQQNLLLQKVKAELEEA 212
E R LE Q LQ+ LE + ++++ + + + EE
Sbjct: 418 EEEA----------ARQRQRIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEE 467
Query: 213 KRFHISLQESYHSLKERSLTDLQLLLESLQEEKCRQALMEEQVNGRLQ 260
++ +Q +ER + Q E LQ+E +Q+ +Q +L+
Sbjct: 468 EKLKQLMQ--LKEEQERYIERAQQEKEELQQEMAQQSRSLQQAQQQLE 513
>gi|62821790 leucine zipper protein 2 [Homo sapiens]
Length = 346
Score = 38.9 bits (89), Expect = 0.009
Identities = 37/160 (23%), Positives = 66/160 (41%), Gaps = 20/160 (12%)
Query: 181 QSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDLQLLLES 240
Q Q ET + A++ + +K E+E + LQ SLK + L+ +L
Sbjct: 91 QEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKLCGIH 150
Query: 241 LQEEKCRQALMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKS 300
+E K ++Q QL E+ K +L +++ L + A E+ +
Sbjct: 151 AEESK------------KIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALD 198
Query: 301 RISKLEMLQQVTQLEAAEHLQSRPPQMLFKFLSPRLSLAT 340
R S+++ +++ QL + +PP P LSL T
Sbjct: 199 RESQMKAMKETVQLCLTSVFRDQPP--------PPLSLIT 230
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 38.5 bits (88), Expect = 0.011
Identities = 39/166 (23%), Positives = 68/166 (40%), Gaps = 21/166 (12%)
Query: 170 ASRPFILESRFQSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKER 229
+ + LE+ + L E ED+ Q L + +AELE+ + + + +L+
Sbjct: 352 SEKDLCLENLRKELSAKHQSEMEDLQNQFQKELAEQRAELEKIFQDKNQAERALRNLESH 411
Query: 230 SLTDLQLLLESLQEE--KCRQALMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYER 287
++ L E LQ E +C + L + + QL NL S E + S E
Sbjct: 412 HQAAIEKLREDLQSEHGRCLEDLEFKFKESEKEKQLE-----LENLQASYEDLKAQSQEE 466
Query: 288 AKEIW--------------EITETFKSRISKLEMLQQVTQLEAAEH 319
+ +W E+ E +R S++E L+Q+ Q E +H
Sbjct: 467 IRRLWSQLDSARTSRQELSELHEQLLARTSRVEDLEQLKQREKTQH 512
>gi|8923720 zinc finger, C4H2 domain containing [Homo sapiens]
Length = 224
Score = 38.5 bits (88), Expect = 0.011
Identities = 40/163 (24%), Positives = 75/163 (46%), Gaps = 18/163 (11%)
Query: 176 LESRFQSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDLQ 235
L++ F++L+ ++ Q+ +LLLQ+ A +EE + H + +++K+ S DL
Sbjct: 31 LKAEFEALESEE-RHLKEYKQEMDLLLQEKMAHVEELRLIHADINVMENTIKQ-SENDLN 88
Query: 236 LLLESLQEEKCRQALMEEQVNG-RLQGQLNEIYNLKHNLACSEERMAYLSY-ERAKEIWE 293
LLES + ++E V+ R+ L + +L C EE L Y E+ K W+
Sbjct: 89 KLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDL-----CEEEEKLSLDYFEKQKAEWQ 143
Query: 294 -------ITETFKSRISKLEMLQQVTQLEAAE--HLQSRPPQM 327
I E+ + + + LQ + + + + +PP M
Sbjct: 144 TEPQEPPIPESLAAAAAAAQQLQVARKQDTRQTATFRQQPPPM 186
>gi|21450705 leucine rich repeat containing 45 [Homo sapiens]
Length = 670
Score = 38.5 bits (88), Expect = 0.011
Identities = 49/260 (18%), Positives = 113/260 (43%), Gaps = 32/260 (12%)
Query: 69 RDGNTVSYLKLVSKADRHQVPHIQQAFEKVNQRASATIAQIEHRLHQCHQQLQELEEGCR 128
R+ + +L L+ D+ + + K ++ ++A + Q++ L++ H + L+
Sbjct: 252 REEKSKQFLDLMETIDKQR-----EEMAKSSRASAARVGQLQEALNERHSIINALK---- 302
Query: 129 PEGLLLMAESDPANCEPPSEKALLSEPPEPGGEDGPVNLPHASRPFILESRFQSLQQGTC 188
L M E+ A E ++ L E ++ ++ LE + + ++
Sbjct: 303 --AKLQMTEAALALSEQKAQD--LGELLATAEQEQLSLSQRQAKELKLEQQEAAERESKL 358
Query: 189 LETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDLQLLLESLQEE---- 244
L A ++NLLLQ ELE ++F ++ + + +E + +L + ++Q E
Sbjct: 359 LRDLSAANEKNLLLQNQVDELE--RKFRCQQEQLFQTRQEMTSMSAELKMRAIQAEERLD 416
Query: 245 ----KCRQALMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKS 300
+CRQ+L + + ++ E+ ++ +L SE+ M ER + + + +
Sbjct: 417 MEKRRCRQSLEDSE-----SLRIKEVEHMTRHLEESEKAM----QERVQRLEAARLSLEE 467
Query: 301 RISKLEMLQQVTQLEAAEHL 320
+S+++ + +A E L
Sbjct: 468 ELSRVKAAALSERGQAEEEL 487
Score = 36.6 bits (83), Expect = 0.042
Identities = 35/119 (29%), Positives = 56/119 (47%), Gaps = 11/119 (9%)
Query: 210 EEAKRFHISLQESYHSLKERS--LTDLQLLLESLQEEKCRQALMEEQVNGRLQGQLNE-- 265
E R H+ +E H +E+S DL ++ +EE + + G+LQ LNE
Sbjct: 236 ENQARTHVLSKEVQHLREEKSKQFLDLMETIDKQREEMAKSSRASAARVGQLQEALNERH 295
Query: 266 --IYNLKHNLACSEERMAYLSYERAKEIWEITETFKSRISKLEMLQ----QVTQLEAAE 318
I LK L +E +A LS ++A+++ E+ T + L Q ++ Q EAAE
Sbjct: 296 SIINALKAKLQMTEAALA-LSEQKAQDLGELLATAEQEQLSLSQRQAKELKLEQQEAAE 353
Score = 34.7 bits (78), Expect = 0.16
Identities = 55/276 (19%), Positives = 105/276 (38%), Gaps = 42/276 (15%)
Query: 46 NLQDSVRHRILYLSEQLRVEKASRDGNTVSYLKLVSKADRHQVPHIQQ---AFEKVNQRA 102
++ ++ R + E+L +EK + L K H H+++ A ++ QR
Sbjct: 399 SMSAELKMRAIQAEERLDMEKRRCRQSLEDSESLRIKEVEHMTRHLEESEKAMQERVQRL 458
Query: 103 SATIAQIEHRLHQCHQQLQELEEGCRPEGLLLMAESDPANCEPPSEKALLSEPPEPGGED 162
A +E L + + L E + E L+ A+S +A L E
Sbjct: 459 EAARLSLEEELSRV--KAAALSERGQAEEELIKAKS----------QARLEEQQR----- 501
Query: 163 GPVNLPHASRPFILESRFQSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQES 222
L H L ++ + QG CL+ + V + + ++ ++E +R LQ+
Sbjct: 502 ----LAHLEDKLRLLAQARDEAQGACLQQKQVVAEAQTRVSQLGLQVEGLRRRLEELQQE 557
Query: 223 YHSLKERSLTDLQLLLESLQEEKCRQALMEEQVNGRLQGQLNEIYNLKHNLACSEERMAY 282
+ + ++ + LQE+ NGRLQ +L L+ A E ++
Sbjct: 558 LSLKDQERVAEVSRVRVELQEQ-----------NGRLQAELAAQEALREKAAALERQLKV 606
Query: 283 LSYERAKEIWEITETFKSRISKLEMLQQVTQLEAAE 318
++ + E R S+ L++ +L AE
Sbjct: 607 MASDH-------REALLDRESENASLREKLRLREAE 635
>gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo
sapiens]
Length = 987
Score = 38.1 bits (87), Expect = 0.015
Identities = 52/214 (24%), Positives = 93/214 (43%), Gaps = 28/214 (13%)
Query: 58 LSEQLRVEKASRDGNTVSYLKL---VSKADRHQVPHIQQAFEKVNQRASATIAQIEHRLH 114
+ E L+V +A +D +S +L + KA+ ++ H+ KV + S +H+
Sbjct: 499 VQEMLKVARAEKDLLELSCNELRQELLKANG-EIKHVSSLLAKVEKDYSYLKEICDHQAE 557
Query: 115 QCHQQLQELEEGCRPEGLLLMAESDPANCEPPSEKALLSEPPEPGGEDGPVNLPHASRPF 174
Q + +L+E +ESD E K + E + + V L +
Sbjct: 558 QLSRTSLKLQEKA--------SESD---AEIKDMKETIFELEDQVEQHRAVKLHNNQLIS 606
Query: 175 ILESRFQSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDL 234
LES L++ + D+ +Q L +++K E EE +RF LQ + +
Sbjct: 607 ELESSVIKLEE----QKSDLERQLKTLTKQMKEETEEWRRFQADLQTAVVVAND------ 656
Query: 235 QLLLESLQEEKC--RQALMEEQVNGRLQGQLNEI 266
+ E+ QE + R+ L EE+ N RLQ +L ++
Sbjct: 657 -IKCEAQQELRTVKRKLLEEEEKNARLQKELGDV 689
>gi|75750468 spectrin domain with coiled-coils 1 NSP5a3a [Homo
sapiens]
Length = 709
Score = 38.1 bits (87), Expect = 0.015
Identities = 52/214 (24%), Positives = 93/214 (43%), Gaps = 28/214 (13%)
Query: 58 LSEQLRVEKASRDGNTVSYLKL---VSKADRHQVPHIQQAFEKVNQRASATIAQIEHRLH 114
+ E L+V +A +D +S +L + KA+ ++ H+ KV + S +H+
Sbjct: 499 VQEMLKVARAEKDLLELSCNELRQELLKANG-EIKHVSSLLAKVEKDYSYLKEICDHQAE 557
Query: 115 QCHQQLQELEEGCRPEGLLLMAESDPANCEPPSEKALLSEPPEPGGEDGPVNLPHASRPF 174
Q + +L+E +ESD E K + E + + V L +
Sbjct: 558 QLSRTSLKLQEKA--------SESD---AEIKDMKETIFELEDQVEQHRAVKLHNNQLIS 606
Query: 175 ILESRFQSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDL 234
LES L++ + D+ +Q L +++K E EE +RF LQ + +
Sbjct: 607 ELESSVIKLEE----QKSDLERQLKTLTKQMKEETEEWRRFQADLQTAVVVAND------ 656
Query: 235 QLLLESLQEEKC--RQALMEEQVNGRLQGQLNEI 266
+ E+ QE + R+ L EE+ N RLQ +L ++
Sbjct: 657 -IKCEAQQELRTVKRKLLEEEEKNARLQKELGDV 689
>gi|75750472 spectrin domain with coiled-coils 1 NSP5b3b [Homo
sapiens]
Length = 1068
Score = 38.1 bits (87), Expect = 0.015
Identities = 52/214 (24%), Positives = 93/214 (43%), Gaps = 28/214 (13%)
Query: 58 LSEQLRVEKASRDGNTVSYLKL---VSKADRHQVPHIQQAFEKVNQRASATIAQIEHRLH 114
+ E L+V +A +D +S +L + KA+ ++ H+ KV + S +H+
Sbjct: 580 VQEMLKVARAEKDLLELSCNELRQELLKANG-EIKHVSSLLAKVEKDYSYLKEICDHQAE 638
Query: 115 QCHQQLQELEEGCRPEGLLLMAESDPANCEPPSEKALLSEPPEPGGEDGPVNLPHASRPF 174
Q + +L+E +ESD E K + E + + V L +
Sbjct: 639 QLSRTSLKLQEKA--------SESD---AEIKDMKETIFELEDQVEQHRAVKLHNNQLIS 687
Query: 175 ILESRFQSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDL 234
LES L++ + D+ +Q L +++K E EE +RF LQ + +
Sbjct: 688 ELESSVIKLEE----QKSDLERQLKTLTKQMKEETEEWRRFQADLQTAVVVAND------ 737
Query: 235 QLLLESLQEEKC--RQALMEEQVNGRLQGQLNEI 266
+ E+ QE + R+ L EE+ N RLQ +L ++
Sbjct: 738 -IKCEAQQELRTVKRKLLEEEEKNARLQKELGDV 770
>gi|75750466 spectrin domain with coiled-coils 1 NSP5b3a [Homo
sapiens]
Length = 790
Score = 38.1 bits (87), Expect = 0.015
Identities = 52/214 (24%), Positives = 93/214 (43%), Gaps = 28/214 (13%)
Query: 58 LSEQLRVEKASRDGNTVSYLKL---VSKADRHQVPHIQQAFEKVNQRASATIAQIEHRLH 114
+ E L+V +A +D +S +L + KA+ ++ H+ KV + S +H+
Sbjct: 580 VQEMLKVARAEKDLLELSCNELRQELLKANG-EIKHVSSLLAKVEKDYSYLKEICDHQAE 638
Query: 115 QCHQQLQELEEGCRPEGLLLMAESDPANCEPPSEKALLSEPPEPGGEDGPVNLPHASRPF 174
Q + +L+E +ESD E K + E + + V L +
Sbjct: 639 QLSRTSLKLQEKA--------SESD---AEIKDMKETIFELEDQVEQHRAVKLHNNQLIS 687
Query: 175 ILESRFQSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDL 234
LES L++ + D+ +Q L +++K E EE +RF LQ + +
Sbjct: 688 ELESSVIKLEE----QKSDLERQLKTLTKQMKEETEEWRRFQADLQTAVVVAND------ 737
Query: 235 QLLLESLQEEKC--RQALMEEQVNGRLQGQLNEI 266
+ E+ QE + R+ L EE+ N RLQ +L ++
Sbjct: 738 -IKCEAQQELRTVKRKLLEEEEKNARLQKELGDV 770
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 38.1 bits (87), Expect = 0.015
Identities = 56/281 (19%), Positives = 108/281 (38%), Gaps = 29/281 (10%)
Query: 60 EQLRVEKASRDGNTVSYLKLVSKADRHQVPHIQQAFEKVNQRASATIAQIEHRLHQCHQQ 119
E L + ++D T++ +++ + Q+ + + + + I+ L H Q
Sbjct: 1309 ELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERD-NLKTIKEALEVKHDQ 1367
Query: 120 LQE---------LEEGCRPEGLLLMAESDPANCE--------PPSEKALLSEPPEPGGED 162
L+E E + E L M E D + P + ALL E G
Sbjct: 1368 LKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLS 1427
Query: 163 GPVNLPHASRPFILESR--FQSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQ 220
+ H + + + Q LQ+ E++ + + ++ K EE K H L+
Sbjct: 1428 KRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLK 1487
Query: 221 ESYHSLKERSLTDLQLLLESLQEEKCRQALMEEQVNGRLQGQLNEIYNLKHNLACSEERM 280
E +E ++ +L++ L + E E +N +LQ ++ EIY + +
Sbjct: 1488 E-----QEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISE 1542
Query: 281 AYLSYERAKEIWEITETFKSRISKLEMLQQVTQLEAAEHLQ 321
E+ E+ + E K++ S L+ ++ LE LQ
Sbjct: 1543 V---QEKVNELKQFKEHRKAKDSALQSIES-KMLELTNRLQ 1579
Score = 37.0 bits (84), Expect = 0.032
Identities = 36/125 (28%), Positives = 64/125 (51%), Gaps = 16/125 (12%)
Query: 190 ETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDLQLLLESLQEEKCRQA 249
+ E VAQ++N ++K E R L E LKE+S + LQE++ +Q
Sbjct: 1097 QQEIVAQEKNHAIKKEG----ELSRTCDRLAEVEEKLKEKS--------QQLQEKQ-QQL 1143
Query: 250 LMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYER---AKEIWEITETFKSRISKLE 306
L ++ +Q ++NEI NLK+ L E + ++ ER A+++ E E KS + +
Sbjct: 1144 LNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERK 1203
Query: 307 MLQQV 311
+L+++
Sbjct: 1204 VLKEL 1208
Score = 30.8 bits (68), Expect = 2.3
Identities = 33/119 (27%), Positives = 52/119 (43%), Gaps = 11/119 (9%)
Query: 203 QKVKAELEEAKRFHISLQESYHSLKERSLTDLQLLLESLQEEKCRQALMEEQVNGRLQGQ 262
QK K LEE +R + QE + KE D L +L+ E + ++ +Q +
Sbjct: 831 QKYKMVLEENERMN---QEIVNLSKEAQKFDSSL--GALKTELSYKTQELQEKTREVQER 885
Query: 263 LNEIYNLKHNLACSE------ERMAYLSYERAKEIWEITETFKSRISKLEMLQQVTQLE 315
LNE+ LK L + ER L E+ ++ E +T L+ LQ+ Q+E
Sbjct: 886 LNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIE 944
>gi|4505257 moesin [Homo sapiens]
Length = 577
Score = 37.7 bits (86), Expect = 0.019
Identities = 40/152 (26%), Positives = 70/152 (46%), Gaps = 22/152 (14%)
Query: 177 ESRFQSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDLQL 236
E + Q + LE E +++ + +K K ++E K L E ++E++ Q
Sbjct: 311 EEKHQKQMERAMLENE---KKKREMAEKEKEKIEREKE---ELMERLKQIEEQTKKAQQE 364
Query: 237 LLESLQEEKCRQALMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAK------- 289
L EE+ R+AL EQ R Q + ++ + ++E + S ++ K
Sbjct: 365 L-----EEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLAL 419
Query: 290 EIWEITETFKSRISKLEMLQQVTQLEAAEHLQ 321
E+ E+T +RIS+LEM +Q + EA E Q
Sbjct: 420 EMAELT----ARISQLEMARQKKESEAVEWQQ 447
>gi|32698688 citron [Homo sapiens]
Length = 2027
Score = 37.4 bits (85), Expect = 0.025
Identities = 33/101 (32%), Positives = 52/101 (51%), Gaps = 7/101 (6%)
Query: 190 ETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDLQLLLESLQEEKCRQA 249
+ E +A QQ L QK+KAE K ++ E H++ E + LQ LE+ E + +Q
Sbjct: 1097 KAEILALQQALKEQKLKAESLSDK---LNDLEKKHAMLEMNARSLQQKLET--ERELKQR 1151
Query: 250 LMEEQ--VNGRLQGQLNEIYNLKHNLACSEERMAYLSYERA 288
L+EEQ + ++ Q N I+ L L + +R L ER+
Sbjct: 1152 LLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERS 1192
>gi|82775371 coiled-coil domain containing 93 [Homo sapiens]
Length = 631
Score = 37.4 bits (85), Expect = 0.025
Identities = 28/112 (25%), Positives = 47/112 (41%), Gaps = 2/112 (1%)
Query: 189 LETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDLQLLLESLQEEKCRQ 248
L V + QK K LEE + H SLQ Y+ K ++LT+L+ E L +E+
Sbjct: 314 LHRRKVISLNKQIAQKTK-HLEELRASHTSLQARYNEAK-KTLTELKTYSEKLDKEQAAL 371
Query: 249 ALMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKS 300
+E + + + L + + NL E+ E + + E K+
Sbjct: 372 EKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIENLKA 423
>gi|134152674 rabaptin, RAB GTPase binding effector protein 1
isoform 2 [Homo sapiens]
Length = 829
Score = 37.4 bits (85), Expect = 0.025
Identities = 34/128 (26%), Positives = 59/128 (46%), Gaps = 15/128 (11%)
Query: 192 EDVAQQQNLLLQKVKAELEEAKRFHISLQES------YHSLKERSLTDLQLLLESLQEEK 245
E+VA Q ++ + V+ + +FH+ L++ Y ER + DL+ L QEE+
Sbjct: 112 EEVASLQAVMKETVR---DYEHQFHLRLEQERTQWAQYRESAEREIADLRRRLSEGQEEE 168
Query: 246 CRQALME------EQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFK 299
+ M+ E++ + EI LK L +E+++ L + KE+ E K
Sbjct: 169 NLENEMKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAEDKIKELEASKVKELNHYLEAEK 228
Query: 300 SRISKLEM 307
S + LEM
Sbjct: 229 SCRTDLEM 236
Score = 29.6 bits (65), Expect = 5.2
Identities = 40/179 (22%), Positives = 68/179 (37%), Gaps = 20/179 (11%)
Query: 177 ESRFQSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRF-------------HISLQESY 223
E + LQQG DV +Q +L+Q + EE R H+SLQ++
Sbjct: 607 EILLEELQQGLSQAKRDVQEQMAVLMQSREQVSEELVRLQKDNDSLQGKHSLHVSLQQAE 666
Query: 224 HSLKERSLTDLQLLLESLQEEKCRQALMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYL 283
+ + L+ L+ +E+ + V +L+ EI LK + + L
Sbjct: 667 DFILPDTTEALRELVLKYREDIINVRTAADHVEEKLKA---EILFLKEQIQAEQCLKENL 723
Query: 284 SYERAKEIWEITETFKSRISKLEMLQQVTQLEAAEHLQSRPPQMLFKFLSPRLSLATVL 342
EI E K I+ + L+ + E Q+ Q++F+ + L T L
Sbjct: 724 EETLQLEI----ENCKEEIASISSLKAELERIKVEKGQATVEQLMFEEKNKAQRLQTEL 778
>gi|50658082 centrosomal protein 70 kDa [Homo sapiens]
Length = 597
Score = 37.4 bits (85), Expect = 0.025
Identities = 47/208 (22%), Positives = 91/208 (43%), Gaps = 32/208 (15%)
Query: 140 PANCEPPSEKALLSEPPEPGGEDGPVN---LPHASRPFILESRF-------------QSL 183
P + PS++ L++E + E +N + H +P L R Q +
Sbjct: 8 PQDSSQPSDR-LMTEKQQEEAEWESINVLLMMHGLKPLSLVKRTDLKDLIIFDKQSSQRM 66
Query: 184 QQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDLQLLLESLQE 243
+Q L E+ + QQN++ + + E + R + L++S + +E+ DL+ ++ES+
Sbjct: 67 RQNLKLLVEETSCQQNMIQELI--ETNQQLRNELQLEQSRAANQEQRANDLEQIMESV-- 122
Query: 244 EKCRQALMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKS--- 300
K + +E++ R Q N+I +L+ + + + +R ++ ET S
Sbjct: 123 -KSKIGELEDESLSRACHQQNKIKDLQKEQKTLQVKCQHYKKKRTEQ----EETIASLQM 177
Query: 301 ---RISKLEMLQQVTQLEAAEHLQSRPP 325
R+ K E + VTQ +L R P
Sbjct: 178 EVCRLKKEEEDRIVTQNRVFAYLCKRVP 205
>gi|45439327 periplakin [Homo sapiens]
Length = 1756
Score = 37.4 bits (85), Expect = 0.025
Identities = 41/164 (25%), Positives = 70/164 (42%), Gaps = 19/164 (11%)
Query: 176 LESRFQSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYH--SLKERSLTD 233
L+ R +L+Q E V Q ++LQ+ + E + L+E H L E L
Sbjct: 1423 LQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLRLQLEEEQHRRQLLEGELET 1482
Query: 234 LQLLLESLQEEKCRQALM-----------EEQVNGRLQGQLNEIYNLKHNLACS----EE 278
L+ L +L++ + ++ ++ EQ RL+ L E K L E
Sbjct: 1483 LRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEA 1542
Query: 279 RMAYLSYERAKEIWEITETFKSRISKLEMLQQVTQLEAAEHLQS 322
R++ L + +K E+ + + KL++ +Q QLE LQS
Sbjct: 1543 RLSELEFHNSKSSKEL-DFLREENHKLQLERQNLQLE-TRRLQS 1584
>gi|31377798 rabaptin, RAB GTPase binding effector protein 1 isoform
1 [Homo sapiens]
Length = 862
Score = 37.4 bits (85), Expect = 0.025
Identities = 34/128 (26%), Positives = 59/128 (46%), Gaps = 15/128 (11%)
Query: 192 EDVAQQQNLLLQKVKAELEEAKRFHISLQES------YHSLKERSLTDLQLLLESLQEEK 245
E+VA Q ++ + V+ + +FH+ L++ Y ER + DL+ L QEE+
Sbjct: 112 EEVASLQAVMKETVR---DYEHQFHLRLEQERTQWAQYRESAEREIADLRRRLSEGQEEE 168
Query: 246 CRQALME------EQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFK 299
+ M+ E++ + EI LK L +E+++ L + KE+ E K
Sbjct: 169 NLENEMKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAEDKIKELEASKVKELNHYLEAEK 228
Query: 300 SRISKLEM 307
S + LEM
Sbjct: 229 SCRTDLEM 236
Score = 33.9 bits (76), Expect = 0.27
Identities = 50/214 (23%), Positives = 83/214 (38%), Gaps = 57/214 (26%)
Query: 177 ESRFQSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRF-------------HISLQE-- 221
E + LQQG DV +Q +L+Q + EE R H+SLQ+
Sbjct: 607 EILLEELQQGLSQAKRDVQEQMAVLMQSREQVSEELVRLQKDNDSLQGKHSLHVSLQQAE 666
Query: 222 ---------------------------SYHSLKERSLTDLQLLLESLQEEKCRQALMEEQ 254
+ ++E+ ++ L E +Q E+C + +EE
Sbjct: 667 DFILPDTTEALRELVLKYREDIINVRTAADHVEEKLKAEILFLKEQIQAEQCLKENLEET 726
Query: 255 VNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAK-EIWEITETFKSRISKLEMLQQV-- 311
+ QL EI N K +A A L ER K E ++ T + + +LE LQ++
Sbjct: 727 L------QL-EIENCKEEIASISSLKAEL--ERIKVEKGQLESTLREKSQQLESLQEIKI 777
Query: 312 ---TQLEAAEHLQSRPPQMLFKFLSPRLSLATVL 342
QL+ ++ Q++F+ + L T L
Sbjct: 778 SLEEQLKKETAAKATVEQLMFEEKNKAQRLQTEL 811
Score = 32.0 bits (71), Expect = 1.0
Identities = 20/82 (24%), Positives = 44/82 (53%), Gaps = 2/82 (2%)
Query: 44 AHNLQDSVRHRILYLSEQLRVEKASRDGNTVSYLKLVSKADRHQVPHIQQAFEKVNQRAS 103
A ++++ ++ IL+L EQ++ E+ ++ N L+L + + ++ I ++ +R
Sbjct: 695 ADHVEEKLKAEILFLKEQIQAEQCLKE-NLEETLQLEIENCKEEIASISSLKAEL-ERIK 752
Query: 104 ATIAQIEHRLHQCHQQLQELEE 125
Q+E L + QQL+ L+E
Sbjct: 753 VEKGQLESTLREKSQQLESLQE 774
Score = 28.9 bits (63), Expect = 8.8
Identities = 26/136 (19%), Positives = 64/136 (47%), Gaps = 10/136 (7%)
Query: 181 QSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDLQLLLES 240
++L++ LE E+ +++ + +KAELE K L+ + K + L LQ + S
Sbjct: 721 ENLEETLQLEIEN-CKEEIASISSLKAELERIKVEKGQLESTLRE-KSQQLESLQEIKIS 778
Query: 241 LQEEKCRQALMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKS 300
L+E+ ++ + V + + N+ L+ L SE+ ++ ++++T +
Sbjct: 779 LEEQLKKETAAKATVEQLMFEEKNKAQRLQTELDVSEQVQ--------RDFVKLSQTLQV 830
Query: 301 RISKLEMLQQVTQLEA 316
++ ++ + ++ A
Sbjct: 831 QLERIRQADSLERIRA 846
>gi|14249254 EF-hand calcium binding domain 4B isoform c [Homo
sapiens]
Length = 395
Score = 37.0 bits (84), Expect = 0.032
Identities = 32/146 (21%), Positives = 67/146 (45%), Gaps = 11/146 (7%)
Query: 176 LESRFQSLQQGTCLETEDVAQQQN----LLLQKVKAELEEAKRFHISLQESYHSLKERSL 231
L S F+ + ++ +++N L +K+ A EE + + +++ S KE+ L
Sbjct: 193 LLSNFEDFLTRIISQLQEAHEEKNELECALKRKIAAYDEEIQHLYEEMEQQIKSEKEQFL 252
Query: 232 TD----LQLLLESLQEEK-CRQALMEE--QVNGRLQGQLNEIYNLKHNLACSEERMAYLS 284
Q + L+++ C++ +E+ Q RL+GQ +++ KH ++ +
Sbjct: 253 LKDTERFQARSQELEQKLLCKEQELEQLTQKQKRLEGQCTALHHDKHETKAENTKLKLTN 312
Query: 285 YERAKEIWEITETFKSRISKLEMLQQ 310
E A+E+ + + +LE LQQ
Sbjct: 313 QELARELERTSWELQDAQQQLESLQQ 338
Score = 33.5 bits (75), Expect = 0.36
Identities = 51/202 (25%), Positives = 83/202 (41%), Gaps = 34/202 (16%)
Query: 58 LSEQLRVEKASRDGNTVSYLKLVSKADRHQVPHIQQAFEKVNQRASATIAQIEHRLHQCH 117
L ++L +K D + V L L K + PH+ FE + +I +L + H
Sbjct: 163 LMDRLGAQKVLEDESDVKQLWLQLKKEE---PHLLSNFEDF-------LTRIISQLQEAH 212
Query: 118 QQLQELEEGCRPEGLLLMAESDPANCEPPSEKALLSEPPEPGGEDGPVNLPHASRPFILE 177
++ ELE C + + + + + E+ + SE + L R +
Sbjct: 213 EEKNELE--CALKRKIAAYDEEIQHLYEEMEQQIKSEKEQ-------FLLKDTER---FQ 260
Query: 178 SRFQSLQQGTCL---ETEDVAQQQNLL------LQKVKAELE-EAKRFHISLQESYHSLK 227
+R Q L+Q E E + Q+Q L L K E + E + ++ QE L+
Sbjct: 261 ARSQELEQKLLCKEQELEQLTQKQKRLEGQCTALHHDKHETKAENTKLKLTNQELARELE 320
Query: 228 ERS--LTDLQLLLESLQEEKCR 247
S L D Q LESLQ+E C+
Sbjct: 321 RTSWELQDAQQQLESLQQEACK 342
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.130 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,234,829
Number of Sequences: 37866
Number of extensions: 815102
Number of successful extensions: 4835
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 234
Number of HSP's that attempted gapping in prelim test: 4427
Number of HSP's gapped (non-prelim): 637
length of query: 410
length of database: 18,247,518
effective HSP length: 105
effective length of query: 305
effective length of database: 14,271,588
effective search space: 4352834340
effective search space used: 4352834340
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.