BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo sapiens] (2191 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 4523 0.0 gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 4484 0.0 gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 4459 0.0 gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 2078 0.0 gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 1825 0.0 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 116 3e-25 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 114 8e-25 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 113 2e-24 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 113 2e-24 gi|48762934 alpha 2 type I collagen [Homo sapiens] 113 2e-24 gi|5453638 AT rich interactive domain 3B [Homo sapiens] 106 3e-22 gi|4885193 AT rich interactive domain 3A (BRIGHT- like) protein ... 104 8e-22 gi|57864582 hornerin [Homo sapiens] 102 3e-21 gi|62865637 AT rich interactive domain 3C (BRIGHT- like) [Homo s... 102 5e-21 gi|109255251 loricrin [Homo sapiens] 99 3e-20 gi|55750053 atrophin-1 [Homo sapiens] 98 8e-20 gi|55750041 atrophin-1 [Homo sapiens] 98 8e-20 gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] 97 2e-19 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 95 7e-19 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 95 9e-19 gi|55956910 meningioma 1 [Homo sapiens] 93 3e-18 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 92 7e-18 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 92 7e-18 gi|163965366 nascent polypeptide-associated complex alpha subuni... 92 7e-18 gi|62122917 filaggrin family member 2 [Homo sapiens] 91 1e-17 gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 91 1e-17 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 91 1e-17 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 91 2e-17 gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 89 5e-17 gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 89 5e-17 >gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo sapiens] Length = 2191 Score = 4523 bits (11731), Expect = 0.0 Identities = 2191/2191 (100%), Positives = 2191/2191 (100%) Query: 1 METGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQ 60 METGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQ Sbjct: 1 METGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQ 60 Query: 61 QQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPL 120 QQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPL Sbjct: 61 QQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPL 120 Query: 121 LSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA 180 LSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA Sbjct: 121 LSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA 180 Query: 181 PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHY 240 PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHY Sbjct: 181 PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHY 240 Query: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY 300 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY Sbjct: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY 300 Query: 301 GGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPT 360 GGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPT Sbjct: 301 GGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPT 360 Query: 361 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD 420 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD Sbjct: 361 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD 420 Query: 421 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ 480 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ Sbjct: 421 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ 480 Query: 481 PQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYG 540 PQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYG Sbjct: 481 PQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYG 540 Query: 541 QQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLA 600 QQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLA Sbjct: 541 QQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLA 600 Query: 601 PGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQS 660 PGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQS Sbjct: 601 PGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQS 660 Query: 661 PFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSH 720 PFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSH Sbjct: 661 PFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSH 720 Query: 721 PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSG 780 PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSG Sbjct: 721 PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSG 780 Query: 781 TYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGR 840 TYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGR Sbjct: 781 TYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGR 840 Query: 841 MPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQ 900 MPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQ Sbjct: 841 MPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQ 900 Query: 901 SRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMS 960 SRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMS Sbjct: 901 SRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMS 960 Query: 961 PGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLT 1020 PGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLT Sbjct: 961 PGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLT 1020 Query: 1021 FMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAA 1080 FMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAA Sbjct: 1021 FMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAA 1080 Query: 1081 SSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQST 1140 SSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQST Sbjct: 1081 SSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQST 1140 Query: 1141 GSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNA 1200 GSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNA Sbjct: 1141 GSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNA 1200 Query: 1201 PYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAM 1260 PYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAM Sbjct: 1201 PYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAM 1260 Query: 1261 SNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDG 1320 SNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDG Sbjct: 1261 SNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDG 1320 Query: 1321 MYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQI 1380 MYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQI Sbjct: 1321 MYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQI 1380 Query: 1381 QTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDD 1440 QTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDD Sbjct: 1381 QTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDD 1440 Query: 1441 MMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPAS 1500 MMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPAS Sbjct: 1441 MMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPAS 1500 Query: 1501 FQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQP 1560 FQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQP Sbjct: 1501 FQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQP 1560 Query: 1561 VLKQRRKITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSG 1620 VLKQRRKITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSG Sbjct: 1561 VLKQRRKITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSG 1620 Query: 1621 FLELLVEYFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECI 1680 FLELLVEYFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECI Sbjct: 1621 FLELLVEYFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECI 1680 Query: 1681 DDDEEDEEDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLF 1740 DDDEEDEEDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLF Sbjct: 1681 DDDEEDEEDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLF 1740 Query: 1741 VVDRSDKLGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKE 1800 VVDRSDKLGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKE Sbjct: 1741 VVDRSDKLGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKE 1800 Query: 1801 QEGKGDSEEQQEKSIIATIDDVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKL 1860 QEGKGDSEEQQEKSIIATIDDVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKL Sbjct: 1801 QEGKGDSEEQQEKSIIATIDDVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKL 1860 Query: 1861 LEDEPRSRDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKL 1920 LEDEPRSRDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKL Sbjct: 1861 LEDEPRSRDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKL 1920 Query: 1921 ILLHHEHPERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLS 1980 ILLHHEHPERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLS Sbjct: 1921 ILLHHEHPERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLS 1980 Query: 1981 AYTESICLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDL 2040 AYTESICLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDL Sbjct: 1981 AYTESICLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDL 2040 Query: 2041 ILATPPFSRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGN 2100 ILATPPFSRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGN Sbjct: 2041 ILATPPFSRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGN 2100 Query: 2101 LISFLEDGVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLH 2160 LISFLEDGVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLH Sbjct: 2101 LISFLEDGVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLH 2160 Query: 2161 EGRLLDISISAVLNSLVASVICDVLFQIGQL 2191 EGRLLDISISAVLNSLVASVICDVLFQIGQL Sbjct: 2161 EGRLLDISISAVLNSLVASVICDVLFQIGQL 2191 >gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo sapiens] Length = 2178 Score = 4484 bits (11629), Expect = 0.0 Identities = 2178/2191 (99%), Positives = 2178/2191 (99%), Gaps = 13/2191 (0%) Query: 1 METGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQ 60 METGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQ Sbjct: 1 METGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQ 60 Query: 61 QQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPL 120 QQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPL Sbjct: 61 QQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPL 120 Query: 121 LSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA 180 LSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA Sbjct: 121 LSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA 180 Query: 181 PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHY 240 PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHY Sbjct: 181 PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHY 240 Query: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY 300 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY Sbjct: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY 300 Query: 301 GGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPT 360 GGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPT Sbjct: 301 GGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPT 360 Query: 361 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD 420 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD Sbjct: 361 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD 420 Query: 421 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ 480 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ Sbjct: 421 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ 480 Query: 481 PQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYG 540 PQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQ MPPQYG Sbjct: 481 PQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQ-------------MPPQYG 527 Query: 541 QQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLA 600 QQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLA Sbjct: 528 QQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLA 587 Query: 601 PGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQS 660 PGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQS Sbjct: 588 PGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQS 647 Query: 661 PFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSH 720 PFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSH Sbjct: 648 PFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSH 707 Query: 721 PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSG 780 PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSG Sbjct: 708 PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSG 767 Query: 781 TYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGR 840 TYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGR Sbjct: 768 TYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGR 827 Query: 841 MPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQ 900 MPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQ Sbjct: 828 MPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQ 887 Query: 901 SRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMS 960 SRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMS Sbjct: 888 SRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMS 947 Query: 961 PGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLT 1020 PGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLT Sbjct: 948 PGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLT 1007 Query: 1021 FMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAA 1080 FMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAA Sbjct: 1008 FMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAA 1067 Query: 1081 SSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQST 1140 SSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQST Sbjct: 1068 SSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQST 1127 Query: 1141 GSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNA 1200 GSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNA Sbjct: 1128 GSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNA 1187 Query: 1201 PYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAM 1260 PYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAM Sbjct: 1188 PYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAM 1247 Query: 1261 SNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDG 1320 SNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDG Sbjct: 1248 SNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDG 1307 Query: 1321 MYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQI 1380 MYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQI Sbjct: 1308 MYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQI 1367 Query: 1381 QTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDD 1440 QTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDD Sbjct: 1368 QTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDD 1427 Query: 1441 MMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPAS 1500 MMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPAS Sbjct: 1428 MMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPAS 1487 Query: 1501 FQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQP 1560 FQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQP Sbjct: 1488 FQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQP 1547 Query: 1561 VLKQRRKITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSG 1620 VLKQRRKITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSG Sbjct: 1548 VLKQRRKITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSG 1607 Query: 1621 FLELLVEYFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECI 1680 FLELLVEYFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECI Sbjct: 1608 FLELLVEYFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECI 1667 Query: 1681 DDDEEDEEDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLF 1740 DDDEEDEEDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLF Sbjct: 1668 DDDEEDEEDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLF 1727 Query: 1741 VVDRSDKLGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKE 1800 VVDRSDKLGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKE Sbjct: 1728 VVDRSDKLGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKE 1787 Query: 1801 QEGKGDSEEQQEKSIIATIDDVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKL 1860 QEGKGDSEEQQEKSIIATIDDVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKL Sbjct: 1788 QEGKGDSEEQQEKSIIATIDDVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKL 1847 Query: 1861 LEDEPRSRDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKL 1920 LEDEPRSRDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKL Sbjct: 1848 LEDEPRSRDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKL 1907 Query: 1921 ILLHHEHPERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLS 1980 ILLHHEHPERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLS Sbjct: 1908 ILLHHEHPERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLS 1967 Query: 1981 AYTESICLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDL 2040 AYTESICLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDL Sbjct: 1968 AYTESICLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDL 2027 Query: 2041 ILATPPFSRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGN 2100 ILATPPFSRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGN Sbjct: 2028 ILATPPFSRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGN 2087 Query: 2101 LISFLEDGVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLH 2160 LISFLEDGVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLH Sbjct: 2088 LISFLEDGVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLH 2147 Query: 2161 EGRLLDISISAVLNSLVASVICDVLFQIGQL 2191 EGRLLDISISAVLNSLVASVICDVLFQIGQL Sbjct: 2148 EGRLLDISISAVLNSLVASVICDVLFQIGQL 2178 >gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo sapiens] Length = 2231 Score = 4459 bits (11565), Expect = 0.0 Identities = 2178/2244 (97%), Positives = 2178/2244 (97%), Gaps = 66/2244 (2%) Query: 1 METGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQ 60 METGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQ Sbjct: 1 METGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQ 60 Query: 61 QQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPL 120 QQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPL Sbjct: 61 QQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPL 120 Query: 121 LSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA 180 LSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA Sbjct: 121 LSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA 180 Query: 181 PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHY 240 PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHY Sbjct: 181 PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHY 240 Query: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY 300 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY Sbjct: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY 300 Query: 301 GGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPT 360 GGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPT Sbjct: 301 GGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPT 360 Query: 361 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD 420 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD Sbjct: 361 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD 420 Query: 421 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ 480 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ Sbjct: 421 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ 480 Query: 481 PQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYG 540 PQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQ MPPQYG Sbjct: 481 PQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQ-------------MPPQYG 527 Query: 541 QQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLA 600 QQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLA Sbjct: 528 QQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLA 587 Query: 601 PGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQS 660 PGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQS Sbjct: 588 PGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQS 647 Query: 661 PFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSH 720 PFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSH Sbjct: 648 PFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSH 707 Query: 721 PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSG 780 PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSG Sbjct: 708 PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSG 767 Query: 781 TYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGR 840 TYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGR Sbjct: 768 TYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGR 827 Query: 841 MPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQ 900 MPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQ Sbjct: 828 MPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQ 887 Query: 901 SRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMS 960 SRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMS Sbjct: 888 SRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMS 947 Query: 961 PGESKLPLPLKADGKEEGTPQPESKSK--------------------------------- 987 PGESKLPLPLKADGKEEGTPQPESKSK Sbjct: 948 PGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSF 1007 Query: 988 --------------------KSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGS 1027 KSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGS Sbjct: 1008 HGDESDSISSPGWPKTPSSPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGS 1067 Query: 1028 PVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQY 1087 PVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQY Sbjct: 1068 PVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQY 1127 Query: 1088 IQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAE 1147 IQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAE Sbjct: 1128 IQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAE 1187 Query: 1148 VPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMS 1207 VPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMS Sbjct: 1188 VPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMS 1247 Query: 1208 MPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQ 1267 MPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQ Sbjct: 1248 MPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQ 1307 Query: 1268 RQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAK 1327 RQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAK Sbjct: 1308 RQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAK 1367 Query: 1328 RHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPP 1387 RHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPP Sbjct: 1368 RHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPP 1427 Query: 1388 QMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQR 1447 QMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQR Sbjct: 1428 QMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQR 1487 Query: 1448 INHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLEN 1507 INHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLEN Sbjct: 1488 INHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLEN 1547 Query: 1508 RMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRK 1567 RMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRK Sbjct: 1548 RMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRK 1607 Query: 1568 ITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFLELLVE 1627 ITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFLELLVE Sbjct: 1608 ITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFLELLVE 1667 Query: 1628 YFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEEDE 1687 YFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEEDE Sbjct: 1668 YFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEEDE 1727 Query: 1688 EDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDK 1747 EDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDK Sbjct: 1728 EDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDK 1787 Query: 1748 LGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKEQEGKGDS 1807 LGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKEQEGKGDS Sbjct: 1788 LGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKEQEGKGDS 1847 Query: 1808 EEQQEKSIIATIDDVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKLLEDEPRS 1867 EEQQEKSIIATIDDVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKLLEDEPRS Sbjct: 1848 EEQQEKSIIATIDDVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKLLEDEPRS 1907 Query: 1868 RDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEH 1927 RDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEH Sbjct: 1908 RDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEH 1967 Query: 1928 PERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAYTESIC 1987 PERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAYTESIC Sbjct: 1968 PERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAYTESIC 2027 Query: 1988 LPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLILATPPF 2047 LPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLILATPPF Sbjct: 2028 LPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLILATPPF 2087 Query: 2048 SRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLED 2107 SRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLED Sbjct: 2088 SRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLED 2147 Query: 2108 GVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLHEGRLLDI 2167 GVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLHEGRLLDI Sbjct: 2148 GVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLHEGRLLDI 2207 Query: 2168 SISAVLNSLVASVICDVLFQIGQL 2191 SISAVLNSLVASVICDVLFQIGQL Sbjct: 2208 SISAVLNSLVASVICDVLFQIGQL 2231 >gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] Length = 2285 Score = 2078 bits (5383), Expect = 0.0 Identities = 1222/2361 (51%), Positives = 1448/2361 (61%), Gaps = 361/2361 (15%) Query: 107 SAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGP 166 +AA +PP PP P + A + E AGG E A + A GP Sbjct: 8 AAASSLGNPPPPP----PSELKKAEQQQREEAGG--EAAAAAAAERGEMKAAAGQESEGP 61 Query: 167 AAVPE--FNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDP 224 A P A ++GG GG GG A + G PG+ Sbjct: 62 AVGPPQPLGKELQDGAESNGGGGG---------GG-------------AGSGGGPGAEPD 99 Query: 225 LQNSH-EGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGA----- 278 L+NS+ P N+ + P GGGGG G G A G G Sbjct: 100 LKNSNGNAGPRPALNN--NLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRS 157 Query: 279 -GAVAAAAAAA-------------AAAAGGGGGG--GYGG---SSAGYG----------- 308 AVAAAAAA AA GGGGG Y G +S +G Sbjct: 158 PSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYP 217 Query: 309 ------------VLSSPRQQGGGMMMGPGGGGAASL-------SKAAAGSAAGGF--QRF 347 LSSPR GG PG G AA+ S A+A S++ F QRF Sbjct: 218 NRSAYPPPAPAYALSSPR---GGT---PGSGAAAAAGSKPPPSSSASASSSSSSFAQQRF 271 Query: 348 ----------AGQNQHPSGATPTLNQLLTSPSPMMRSY----GGSYPEYSSPSAPPPPPS 393 AG ATPTLNQLLTSPS R Y GG Y P+ Sbjct: 272 GAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSA-RGYQGYPGGDYSGGPQDGGAGKGPA 330 Query: 394 QPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPA-MSPGTPG--- 449 SQ A AAA AA+G AQQRSH A MSPG+ G Sbjct: 331 DMASQCWGAAAAAAAAAAASG-------------------GAQQRSHHAPMSPGSSGGGG 371 Query: 450 -PTMGRSQ-GSPMDPMVMKRPQLYGMGSNPHSQ-------PQQSSPYPGGSYGPPGPQRY 500 P Q SPMD M RPQ YG G+NP+SQ PQQ YPG YG PQRY Sbjct: 372 QPLARTPQPSSPMDQMGKMRPQPYG-GTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRY 430 Query: 501 PIGIQGRTPGAMAGMQYPQ-------QQDSGDATWKETFWL---------MPPQYGQQGV 544 P+ +QGR AM G+ Y Q Q SG +T + P Y QQ Sbjct: 431 PMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPP 490 Query: 545 S-------GYCQQGQ---------QPYYSQQP-------------------------QPP 563 S Y QQ Q QP YSQQP QPP Sbjct: 491 SQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPP 550 Query: 564 HLPPQAQ-----YLPSQ-------------------------SQQRYQPQQDMSQEGYGT 593 + PQAQ P Q SQQR+ P Q++SQ+ +G+ Sbjct: 551 YSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGS 610 Query: 594 R--SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQ 651 + S P + K ED+NL Q RPSSLPDLSGSIDDLP GTE LS VS SG +SSQ Sbjct: 611 QASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQ 670 Query: 652 GDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPP 711 G+QSNPAQSPFSPH SPHL I G PSPSPVGSP QSRSGP+SPA++PG+QMPP+PP Sbjct: 671 GEQSNPAQSPFSPHTSPHLPGIRG-PSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPP 729 Query: 712 GSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGIS 771 QS+S HP+++QS + Q+RG+M QRNPQM QY Q G ++SP GGQ+H G+ Sbjct: 730 SGQSDSIMHPSMNQSSIAQDRGYM---QRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMG 786 Query: 772 SFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGIS---ANNQMHGQG 828 S+QQ NS G+YGPQ QYGPQG Y R P Y+ +P+A+Y G GI+ A QMHGQ Sbjct: 787 SYQQ-NSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQP 845 Query: 829 PSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAA 888 P G +P GRM A M NRP+ NM++M P Q G GM PP +NRK QE A Sbjct: 846 GIPPYGTLPPGRMSHASMGNRPYGPNMANMPP-------QVGSGMCPPPGGMNRKTQETA 898 Query: 889 AAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNS 948 A M AANS Q+R +P MNQ G+M + PY Q +N+ + ++N Q PPYSM M N+ Sbjct: 899 VA-MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANN 957 Query: 949 SAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNE 1008 SA +MM G+ KL K + K +GTP+ ESKSKKSSSSTTT EKITK+YELG E Sbjct: 958 SAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGE 1017 Query: 1009 PERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELA 1068 PERK+WVDRYL F EE+ +++LPAVG+KPLDL+RLYV VKEIGGL QVNKNKKWRELA Sbjct: 1018 PERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELA 1077 Query: 1069 TNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKK-QPKLQPPSPAN 1127 TNLNVGTSSSAASSLKKQYIQ L+AFECKIERGE+PPP++F+ D+KK QPK+QPPSPA Sbjct: 1078 TNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAG 1137 Query: 1128 SGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQG-GRSSTISVHDPFSDVS 1186 SGS+QGPQTPQST S+SMAE GDLKPPTPASTPH Q+ P+ G RS+++ + D F+D S Sbjct: 1138 SGSMQGPQTPQST-SSSMAE-GGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGS 1195 Query: 1187 DSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNS 1246 DS+F KRNSMTPN YQ M+ D+MGRM YEPNKDP+G MRK PGS +PFM+ GQ PN Sbjct: 1196 DSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGS-DPFMSSGQGPNG 1254 Query: 1247 SMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDR--------------------------- 1279 M D Y+++ + N+ MG RQ +PYG YDR Sbjct: 1255 GMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNP 1314 Query: 1280 --------------------RHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQP-NYKRHM 1318 RH+ YG Q+ QG PSG P + Q +Y QQ NYKR M Sbjct: 1315 DSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSP-FPSQQTTMYQQQQQNYKRPM 1373 Query: 1319 DGMYGPPAKRHEGDMYNMQYS---------------------------SQQQEMYNQYGG 1351 DG YGPPAKRHEG+MY++ YS S QQ++YNQYG Sbjct: 1374 DGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGN 1433 Query: 1352 SY-----SGPDRRPI---QGQYPYPYSRERMQGP-GQIQTHGIPPQMMGGPLQSSSSEGP 1402 +Y + +RRP Q Q+P+ + R+R+ P G +PPQMMGGP+Q+S+ Sbjct: 1434 AYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQ 1493 Query: 1403 QQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQ 1462 Q MW RNDM Y Y NRQ G Q P Y G+NRTD+M+ DQR NHE WPSH +++ Sbjct: 1494 QGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQP 1553 Query: 1463 PYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPS-MK 1521 PY SA + P+TRPP +YQ PPS+ NHI + SPA R +ENR SPSKSPFL S MK Sbjct: 1554 PY-GPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMK 1612 Query: 1522 MQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRKITSKDIVTPEAWRV 1581 MQK P VP S + P QPP IRR+ITFPPGSVEA+QPVLKQRR++T KDI TPEAWRV Sbjct: 1613 MQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRV 1672 Query: 1582 MMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFLELLVEYFRKCLIDIFGILM 1641 MMSLKSGLLAESTWALDTINILLYDD+++ TFNLSQL G LELLVEYFR+CLI+IFGIL Sbjct: 1673 MMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILK 1732 Query: 1642 EYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEEDEEDEEEDSEKTESDE 1701 EYEVGDP Q+ L S + G+EEE E + E+EE+EE E+DE Sbjct: 1733 EYEVGDPGQRTLLDPGRFSKVSSPAPMEGGEEEE--ELLGPKLEEEEEEEV----VENDE 1786 Query: 1702 KSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDKLGRVQEFNSGLLHW 1761 + IA + D A + K SKFDKLP+KIV+KN+ FVVD SDKLGRVQEF+SGLLHW Sbjct: 1787 E--IAFSGKDKPASENSEEKLISKFDKLPVKIVQKNDPFVVDCSDKLGRVQEFDSGLLHW 1844 Query: 1762 QLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKK--EQEGKGDSEEQQ-------- 1811 ++GGGDTTEHIQTHFESK E+ P R P P A RK EG + +Q+ Sbjct: 1845 RIGGGDTTEHIQTHFESKTELLPSR-PHAPCPPAPRKHVTTAEGTPGTTDQEGPPPDGPP 1903 Query: 1812 EKSIIATIDDVLSARPGALPEDANPGPQT--ESSKFPFGIQQAKSHRNIKLLEDEPRSRD 1869 EK I AT+DD+LS R L ED + ESSKFPFGI A+SHRNIK+LEDEP S+D Sbjct: 1904 EKRITATMDDMLSTRSSTLTEDGAKSSEAIKESSKFPFGISPAQSHRNIKILEDEPHSKD 1963 Query: 1870 ETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEHPE 1929 ETPLCT+ WQDSLAKRC+CVSN +RSLSFVPGND EMSKHPGL+LILGKLILLHH+HPE Sbjct: 1964 ETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPE 2023 Query: 1930 RKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAYTESICLP 1989 RK+AP TYEKEE++D+GV+C+K EWWWDCLE+LR+NTLVTLANISGQLDLS Y ESICLP Sbjct: 2024 RKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLP 2083 Query: 1990 ILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLILATPPFSR 2049 +LDGLLHW VCPSAEAQDPF T+GPN+VLSPQRLVLETL KLSIQDNNVDLILATPPFSR Sbjct: 2084 VLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSR 2143 Query: 2050 QEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLEDGV 2109 EK Y+T+VR++ DRKNPVCREM++ LL+NLAQGD+LAARAIAVQKGSIGNL+ FLED + Sbjct: 2144 LEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSL 2203 Query: 2110 TMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLHEGRLLDISI 2169 Q+QQSQ +L+HMQ PP EP SVDMM RAA+ALLA+A+VDEN SEF L+E RLLDIS+ Sbjct: 2204 AATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISV 2263 Query: 2170 SAVLNSLVASVICDVLFQIGQ 2190 S ++NSLV+ VICDVLF IGQ Sbjct: 2264 SPLMNSLVSQVICDVLFLIGQ 2284 Score = 68.2 bits (165), Expect = 9e-11 Identities = 241/1129 (21%), Positives = 331/1129 (29%), Gaps = 229/1129 (20%) Query: 16 EAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHP 75 + P+ PPHQQ A + QQ Q Q Q QQQQ Q P Sbjct: 520 QQPSQPPHQQSP-----------APYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQP 568 Query: 76 ISNNNSLGGAGGGAPQPGPDMEQ---------PQHGGAKDSAAGGQADPPGPPLLSKPGD 126 + S A PQP Q P + G QA SK G Sbjct: 569 APSTLSQQAA---YPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQ 625 Query: 127 ED-----DAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPG-----GGGGPAAVPEFNNYY 176 ED + P G + +G G P V+ G G A F+ + Sbjct: 626 EDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHT 685 Query: 177 GSAAPASGGPG----GRAGPCFDQHGGQQSPGM--GMMHSASAAAAGAPGSMDPLQN--- 227 P GP G G SP G + + M P N Sbjct: 686 SPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSS 745 Query: 228 --SHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGG--------------GSGGGGGGGGA 271 GY P YS P G GG GS G GG Sbjct: 746 IAQDRGYMQRN-PQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYG 804 Query: 272 GAGG----AGAGAVAAAAAAAAAAAGGGGGGGYGGSSAG------YGVL----------- 310 GG A+ A +A AGG G GG G YG L Sbjct: 805 PQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMG 864 Query: 311 ---------SSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTL 361 + P Q G GM PGG + A A A + QN+ P P + Sbjct: 865 NRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAAN----SIQNRPP--GYPNM 918 Query: 362 NQLLTSPSPMMRSYGGSYPEY----SSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGL 417 NQ MM G+ P Y +S + P P S + G A+ M Sbjct: 919 NQ-----GGMM----GTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEM-- 967 Query: 418 GKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNP 477 MG +PA + + GTP + S K +LY +G P Sbjct: 968 ---MGLGDVKLTPATKMNNK------ADGTPKTESKSKKSSSSTTTNEKITKLYELGGEP 1018 Query: 478 HSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSG------DATWKET 531 + G P GR P + + ++ G + W+E Sbjct: 1019 ERKMWVDRYLAFTEEKAMGMTNLP--AVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWREL 1076 Query: 532 FWLMPPQYGQQGVSGYCQQGQQPYYS--------QQPQP------------PHLPPQAQY 571 + S +Q Q Y+ + P P P + P + Sbjct: 1077 ATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPA 1136 Query: 572 LPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLP 631 Q PQ S G +PP P+ + L R +S+ + + +D Sbjct: 1137 GSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSV-GIQDAFNDGS 1195 Query: 632 TGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSP-VGSPVGSNQ 690 T +S G S + + P+ P+ S+ P P + S G N Sbjct: 1196 DSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPY-GSMRKAPGSDPFMSSGQGPNG 1254 Query: 691 SRSGPISPASIPG---SQMPPQ-------------------PPGSQSESSSHPALSQSPM 728 P S A+ PG M P+ P G+ S + P L P Sbjct: 1255 GMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNL--MPS 1312 Query: 729 PQERGFMAGTQRNPQMAQ--------YGPQ---QTGPSMSPHPSPGGQMHAGISSFQQSN 777 + G + ++ PQ Q YG Q Q PS SP PS M+ + Sbjct: 1313 NPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRP 1372 Query: 778 SSGTYGPQMSQY-------------GPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQM 824 GTYGP ++ G PPA P++ P NQ Sbjct: 1373 MDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPA-QPQPASQQQAAQPSPQQDVYNQY 1431 Query: 825 HGQGPSQPCGAVPLGRMPSAGMQNR-PF--------------------PGNMSSMTPSSP 863 P+ A R P+ G QN+ PF P M +S Sbjct: 1432 GNAYPATATAATE--RRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASA 1489 Query: 864 GMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSF----PGMNQSGLMASSS 919 ++QQG G T N +++ + Q A +R N G S Sbjct: 1490 EVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHG 1549 Query: 920 PYSQPMNNSSSLMNTQAPP---YSMAPAMVNSSAASVGLADMMSPGESK 965 P S+ + PP Y P+M N A + P E++ Sbjct: 1550 TRQPPYGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENR 1598 Score = 48.9 bits (115), Expect = 5e-05 Identities = 223/1049 (21%), Positives = 330/1049 (31%), Gaps = 162/1049 (15%) Query: 21 PPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQ-----------QQQQQQQQQQQQ 69 PP+ Q + ++ H QQQ QQ QQQ Q Q Q Sbjct: 452 PPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQL 511 Query: 70 QQQQHPISNNNSL-GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDED 128 Q Q P S S AP P QH ++ + QA P + + Sbjct: 512 QSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSP----YQQQQPQQ 567 Query: 129 DAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGG 188 AP + + A Y P +QQ P + +GS A + Sbjct: 568 PAPSTLSQQAA--YPQP-----QSQQSQQTAYSQQRFPPPQELSQDSFGSQASS------ 614 Query: 189 RAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGA 248 A GGQ+ + + S ++ GS+D L EG + PG S G Sbjct: 615 -APSMTSSKGGQEDMNLS-LQSRPSSLPDLSGSIDDLPMGTEGALS------PGVSTSGI 666 Query: 249 GGGGGGGGGGGGGSGGGGGGGG-AGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY 307 G G G V + A+ A + +G G+ Sbjct: 667 SSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQ--- 723 Query: 308 GVLSSPRQQGG--GMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLL 365 PR G +M P S+++++ G QR Q P ++P L Sbjct: 724 ---MPPRPPSGQSDSIMHP------SMNQSSIAQDRGYMQR---NPQMPQYSSPQPGSAL 771 Query: 366 TSPSP---------------MMRSYGGSYPEYSSPSAPPPPPSQ---PQSQAAAAGAAAG 407 + P M SYG +Y P P+ P + +AG A G Sbjct: 772 SPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGG 831 Query: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGR---SQGSPMDPM- 463 MG G M Q + SH +M GP M GS M P Sbjct: 832 ----INPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPP 887 Query: 464 --VMKRPQLYGMGSNPHSQPQQSSP--YP----GGSYGPPGPQRYPIGIQGRTPGAMAGM 515 + ++ Q + + + Q+ P YP GG G P G+ +MAGM Sbjct: 888 GGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPP-------YGQGINSMAGM 940 Query: 516 QYPQ-----------QQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPH 564 PQ +G A E L + G S+ + Sbjct: 941 INPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSS 1000 Query: 565 LPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLS 624 + + + +P++ M + Y ++ A G N + +P L L Sbjct: 1001 STTTNEKITKLYELGGEPERKMWVDRYLAFTEEK-AMGMTNLPAVG----RKPLDLYRLY 1055 Query: 625 GSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHAS---PHLSSIPGGPSPSP 681 S+ ++ T+ + + + G S+ A S + I G P P Sbjct: 1056 VSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPP 1115 Query: 682 ---VGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGT 738 + +Q + P SPA GS PQ P S S S + + P P A T Sbjct: 1116 DIFAAADSKKSQPKIQPPSPAG-SGSMQGPQTPQSTSSSMAEGGDLKPPTP------AST 1168 Query: 739 QRNPQMAQYGPQQTGPSMSPHPSPGGQ---MHAGISSFQQSNS---SGTYGPQMSQYGPQ 792 +Q P P MS S G Q S+FQ+ NS + Y P M+ Sbjct: 1169 PH----SQIPPL---PGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMM 1221 Query: 793 GNYSRPP---AYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNR 849 G S P Y + A S P G N M G S+ G LG + Q+ Sbjct: 1222 GRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGM-GDPYSRAAGP-GLGNVAMGPRQHY 1279 Query: 850 PFPGNMSSMTPSSPGMSQQGGPGMGPP----MPTVNRKAQEAAAAVMQAAANSAQSRQGS 905 P+ G + + PG+ +G G P MP+ + + Q R S Sbjct: 1280 PYGGPYDRVR-TEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDS 1338 Query: 906 FPGMNQSGLMASSSPY---------SQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLA 956 + + S SP+ Q N + T PP + S S G Sbjct: 1339 YGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQG 1398 Query: 957 DMMSPGESKLP--LPLKADGKEEGTPQPE 983 P + +LP P A ++ P P+ Sbjct: 1399 ---QPQQQQLPPAQPQPASQQQAAQPSPQ 1424 >gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] Length = 2068 Score = 1825 bits (4726), Expect = 0.0 Identities = 1123/2277 (49%), Positives = 1334/2277 (58%), Gaps = 410/2277 (18%) Query: 107 SAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGP 166 +AA +PP PP P + A + E AGG E A + A GP Sbjct: 8 AAASSLGNPPPPP----PSELKKAEQQQREEAGG--EAAAAAAAERGEMKAAAGQESEGP 61 Query: 167 AAVPE--FNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDP 224 A P A ++GG GG GG A + G PG+ Sbjct: 62 AVGPPQPLGKELQDGAESNGGGGG---------GG-------------AGSGGGPGAEPD 99 Query: 225 LQNSH-EGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGA----- 278 L+NS+ P N+ + P GGGGG G G A G G Sbjct: 100 LKNSNGNAGPRPALNN--NLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRS 157 Query: 279 -GAVAAAAAAA-------------AAAAGGGGGG--GYGG---SSAGYG----------- 308 AVAAAAAA AA GGGGG Y G +S +G Sbjct: 158 PSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYP 217 Query: 309 ------------VLSSPRQQGGGMMMGPGGGGAASL-------SKAAAGSAAGGF--QRF 347 LSSPR GG PG G AA+ S A+A S++ F QRF Sbjct: 218 NRSAYPPPAPAYALSSPR---GGT---PGSGAAAAAGSKPPPSSSASASSSSSSFAQQRF 271 Query: 348 ----------AGQNQHPSGATPTLNQLLTSPSPMMRSY----GGSYPEYSSPSAPPPPPS 393 AG ATPTLNQLLTSPS R Y GG Y P+ Sbjct: 272 GAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSA-RGYQGYPGGDYSGGPQDGGAGKGPA 330 Query: 394 QPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPA-MSPGTPG--- 449 SQ A AAA AA+G AQQRSH A MSPG+ G Sbjct: 331 DMASQCWGAAAAAAAAAAASG-------------------GAQQRSHHAPMSPGSSGGGG 371 Query: 450 -PTMGRSQ-GSPMDPMVMKRPQLYGMGSNPHSQ-------PQQSSPYPGGSYGPPGPQRY 500 P Q SPMD M RPQ YG G+NP+SQ PQQ YPG YG PQRY Sbjct: 372 QPLARTPQPSSPMDQMGKMRPQPYG-GTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRY 430 Query: 501 PIGIQGRTPGAMAGMQYPQ-------QQDSGDATWKETFWL---------MPPQYGQQGV 544 P+ +QGR AM G+ Y Q Q SG +T + P Y QQ Sbjct: 431 PMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPP 490 Query: 545 S-------GYCQQGQ---------QPYYSQQP-------------------------QPP 563 S Y QQ Q QP YSQQP QPP Sbjct: 491 SQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPP 550 Query: 564 HLPPQAQ-----YLPSQ-------------------------SQQRYQPQQDMSQEGYGT 593 + PQAQ P Q SQQR+ P Q++SQ+ +G+ Sbjct: 551 YSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGS 610 Query: 594 R--SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQ 651 + S P + K ED+NL Q RPSSLPDLSGSIDDLP GTE LS VS SG +SSQ Sbjct: 611 QASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQ 670 Query: 652 GDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPP 711 G+QSNPAQSPFSPH SPHL I G PSPSPVGSP QSRSGP+SPA++PG+QMPP+PP Sbjct: 671 GEQSNPAQSPFSPHTSPHLPGIRG-PSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPP 729 Query: 712 GSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGIS 771 QS+S HP+++QS + Q+RG+M QRNPQM QY Q G ++SP GGQ+H G+ Sbjct: 730 SGQSDSIMHPSMNQSSIAQDRGYM---QRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMG 786 Query: 772 SFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGIS---ANNQMHGQG 828 S+QQ NS G+YGPQ QYGPQG Y R P Y+ +P+A+Y G GI+ A QMHGQ Sbjct: 787 SYQQ-NSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQP 845 Query: 829 PSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAA 888 P G +P GRM A M NRP+ NM++M P Q G GM PP +NRK QE A Sbjct: 846 GIPPYGTLPPGRMSHASMGNRPYGPNMANMPP-------QVGSGMCPPPGGMNRKTQETA 898 Query: 889 AAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNS 948 A M AANS Q+R +P MNQ G+M + PY Q +N+ + ++N Q PPYSM M N+ Sbjct: 899 VA-MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANN 957 Query: 949 SAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNE 1008 SA +MM G+ KL K + K +GTP+ ESKSKKSSSSTTT EKITK+YELG E Sbjct: 958 SAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGE 1017 Query: 1009 PERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELA 1068 PERK+WVDRYL F EE+ +++LPAVG+KPLDL+RLYV VKEIGGL QVNKNKKWRELA Sbjct: 1018 PERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELA 1077 Query: 1069 TNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKK-QPKLQPPSPAN 1127 TNLNVGTSSSAASSLKKQYIQ L+AFECKIERGE+PPP++F+ D+KK QPK+QPPSPA Sbjct: 1078 TNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAG 1137 Query: 1128 SGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQG-GRSSTISVHDPFSDVS 1186 SGS+QGPQTPQST S+SMAE GDLKPPTPASTPH Q+ P+ G RS+++ + D F+D S Sbjct: 1138 SGSMQGPQTPQST-SSSMAE-GGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGS 1195 Query: 1187 DSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNS 1246 DS+F KRNSMTPN YQ M+ D+MGRM YEPNKDP+G MRK PG S+PFM+ GQ PN Sbjct: 1196 DSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPG-SDPFMSSGQGPNG 1254 Query: 1247 SMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPG 1306 M D Y+++ + N+ MG RQ +PYG YDR + PG G P G G QP Sbjct: 1255 GMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDR-----VRTEPGIG-PEGNMSTGAPQPN 1308 Query: 1307 LYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYP 1366 L P P+ GMY P Y Q QQQ+ ++ YG +S Sbjct: 1309 LMPSNPD-----SGMYSP-------SRYPPQQQQQQQQRHDSYGNQFS------------ 1344 Query: 1367 YPYSRERMQGPGQIQTHGIPPQMMGGPLQS-SSSEGPQQNMWAARNDMPYPYQNRQGPGG 1425 T G P G P S ++ QQ ++ +P P +NR P Sbjct: 1345 ---------------TQGTP---SGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSP-- 1384 Query: 1426 PTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTP 1485 + P++ S MQ PP P+ Sbjct: 1385 ----------------------------------SKSPFLHSGMKMQK-AGPPVPA---- 1405 Query: 1486 PSLPNHISRAPSPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIR 1545 +HI+ AP V P + +T PP Sbjct: 1406 ----SHIAPAP----------------------------VQPPMIRRDITFPP------- 1426 Query: 1546 REITFPPGSVEASQPVLKQRRKITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLY 1605 GSVEA+QPVLKQRR++T KDI TPEAWRVMMSLKSGLLAESTWALDTINILLY Sbjct: 1427 -------GSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLY 1479 Query: 1606 DDSTVATFNLSQLSGFLELLVEYFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQS 1665 DD+++ TFNLSQL G LELLVEYFR+CLI+IFGIL EYEVGDP Q+ L S Sbjct: 1480 DDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFSKVSSP 1539 Query: 1666 LADDSGKEEEDAECIDDDEEDEEDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASK 1725 + G+EEE E + E+EE+E E E+DE+ IA + D A + K SK Sbjct: 1540 APMEGGEEEE--ELLGPKLEEEEEE----EVVENDEE--IAFSGKDKPASENSEEKLISK 1591 Query: 1726 FDKLPIKIVKKNNLFVVDRSDKLGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPR 1785 FDKLP+KIV+KN+ FVVD SDKLGRVQEF+SGLLHW++GGGDTTEHIQTHFESK E+ P Sbjct: 1592 FDKLPVKIVQKNDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKTELLP- 1650 Query: 1786 RRPPPPLSSAGRK--KEQEGKGDSEEQQ--------EKSIIATIDDVLSARPGALPEDAN 1835 RP P A RK EG + +Q+ EK I AT+DD+LS R L ED Sbjct: 1651 SRPHAPCPPAPRKHVTTAEGTPGTTDQEGPPPDGPPEKRITATMDDMLSTRSSTLTEDGA 1710 Query: 1836 PGPQT--ESSKFPFGIQQAKSHRNIKLLEDEPRSRDETPLCTIAHWQDSLAKRCICVSNI 1893 + ESSKFPFGI A+SHRNIK+LEDEP S+DETPLCT+ WQDSLAKRC+CVSN Sbjct: 1711 KSSEAIKESSKFPFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNT 1770 Query: 1894 VRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEHPERKRAPQTYEKEEDEDKGVACSKDE 1953 +RSLSFVPGND EMSKHPGL+LILGKLILLHH+HPERK+AP TYEKEE++D+GV+C+K E Sbjct: 1771 IRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCNKVE 1830 Query: 1954 WWWDCLEVLRDNTLVTLANISGQLDLSAYTESICLPILDGLLHWMVCPSAEAQDPFPTVG 2013 WWWDCLE+LR+NTLVTLANISGQLDLS Y ESICLP+LDGLLHW VCPSAEAQDPF T+G Sbjct: 1831 WWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLG 1890 Query: 2014 PNSVLSPQRLVLETLCKLSIQDNNVDLILATPPFSRQEKFYATLVRYVGDRKNPVCREMS 2073 PN+VLSPQRLVLETL KLSIQDNNVDLILATPPFSR EK Y+T+VR++ DRKNPVCREM+ Sbjct: 1891 PNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMA 1950 Query: 2074 MALLSNLAQGDALAARAIAVQKGSIGNLISFLEDGVTMAQYQQSQHNLMHMQPPPLEPPS 2133 + LL+NLAQGD+LAARAIAVQKGSIGNL+ FLED + Q+QQSQ +L+HMQ PP EP S Sbjct: 1951 VVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEPTS 2010 Query: 2134 VDMMCRAAKALLAMARVDENRSEFLLHEGRLLDISISAVLNSLVASVICDVLFQIGQ 2190 VDMM RAA+ALLA+A+VDEN SEF L+E RLLDIS+S ++NSLV+ VICDVLF IGQ Sbjct: 2011 VDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQ 2067 Score = 59.7 bits (143), Expect = 3e-08 Identities = 215/971 (22%), Positives = 284/971 (29%), Gaps = 194/971 (19%) Query: 16 EAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHP 75 + P+ PPHQQ A + QQ Q Q Q QQQQ Q P Sbjct: 520 QQPSQPPHQQSP-----------APYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQP 568 Query: 76 ISNNNSLGGAGGGAPQPGPDMEQ---------PQHGGAKDSAAGGQADPPGPPLLSKPGD 126 + S A PQP Q P + G QA SK G Sbjct: 569 APSTLSQQAA---YPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQ 625 Query: 127 ED-----DAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPG-----GGGGPAAVPEFNNYY 176 ED + P G + +G G P V+ G G A F+ + Sbjct: 626 EDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHT 685 Query: 177 GSAAPASGGPG----GRAGPCFDQHGGQQSPGM--GMMHSASAAAAGAPGSMDPLQN--- 227 P GP G G SP G + + M P N Sbjct: 686 SPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSS 745 Query: 228 --SHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGG--------------GSGGGGGGGGA 271 GY P YS P G GG GS G GG Sbjct: 746 IAQDRGYMQRN-PQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYG 804 Query: 272 GAGG----AGAGAVAAAAAAAAAAAGGGGGGGYGGSSAG------YGVL----------- 310 GG A+ A +A AGG G GG G YG L Sbjct: 805 PQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMG 864 Query: 311 ---------SSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTL 361 + P Q G GM PGG + A A A + QN+ P P + Sbjct: 865 NRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAAN----SIQNRPP--GYPNM 918 Query: 362 NQLLTSPSPMMRSYGGSYPEY----SSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGL 417 NQ MM G+ P Y +S + P P S + G A+ M Sbjct: 919 NQ-----GGMM----GTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEM-- 967 Query: 418 GKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNP 477 MG +PA + + GTP + S K +LY +G P Sbjct: 968 ---MGLGDVKLTPATKMNNK------ADGTPKTESKSKKSSSSTTTNEKITKLYELGGEP 1018 Query: 478 HSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSG------DATWKET 531 + G P GR P + + ++ G + W+E Sbjct: 1019 ERKMWVDRYLAFTEEKAMGMTNLP--AVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWREL 1076 Query: 532 FWLMPPQYGQQGVSGYCQQGQQPYYS--------QQPQP------------PHLPPQAQY 571 + S +Q Q Y+ + P P P + P + Sbjct: 1077 ATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPA 1136 Query: 572 LPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLP 631 Q PQ S G +PP P+ + L R +S+ G D Sbjct: 1137 GSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSV----GIQDAFN 1192 Query: 632 TGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQS 691 G+++T S + NP P S + S + G S P P GS Sbjct: 1193 DGSDSTFQKRNSMT---------PNPGYQP-----SMNTSDMMGRMSYEPNKDPYGS--M 1236 Query: 692 RSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQ 751 R P S + Q P G ++ P L M Q P Y + Sbjct: 1237 RKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVA-------MGPRQHYPYGGPYDRVR 1289 Query: 752 TGPSMSPHPSPGGQMHAGI--SSFQQSN-SSGTYGPQMSQYGPQGNYSRPPAYSGVPSA- 807 T P + P G M G + SN SG Y P S+Y PQ + + + Sbjct: 1290 TEPGIGPE----GNMSTGAPQPNLMPSNPDSGMYSP--SRYPPQQQQQQQQRHDSYGNQF 1343 Query: 808 SYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQ 867 S G G + Q Q PL R M+NR P + GM Sbjct: 1344 STQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPR----PMENRTSPSKSPFL---HSGMKM 1396 Query: 868 QGGPGMGPPMP 878 Q GPP+P Sbjct: 1397 QKA---GPPVP 1404 Score = 45.4 bits (106), Expect = 6e-04 Identities = 201/931 (21%), Positives = 296/931 (31%), Gaps = 144/931 (15%) Query: 21 PPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQ-----------QQQQQQQQQQQQ 69 PP+ Q + ++ H QQQ QQ QQQ Q Q Q Sbjct: 452 PPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQL 511 Query: 70 QQQQHPISNNNSL-GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDED 128 Q Q P S S AP P QH ++ + QA P + + Sbjct: 512 QSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSP----YQQQQPQQ 567 Query: 129 DAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGG 188 AP + + A Y P +QQ P + +GS A + Sbjct: 568 PAPSTLSQQAA--YPQP-----QSQQSQQTAYSQQRFPPPQELSQDSFGSQASS------ 614 Query: 189 RAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGA 248 A GGQ+ + + S ++ GS+D L EG + PG S G Sbjct: 615 -APSMTSSKGGQEDMNLS-LQSRPSSLPDLSGSIDDLPMGTEGALS------PGVSTSGI 666 Query: 249 GGGGGGGGGGGGGSGGGGGGGG-AGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY 307 G G G V + A+ A + +G G+ Sbjct: 667 SSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQ--- 723 Query: 308 GVLSSPRQQGG--GMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLL 365 PR G +M P S+++++ G QR Q P ++P L Sbjct: 724 ---MPPRPPSGQSDSIMHP------SMNQSSIAQDRGYMQR---NPQMPQYSSPQPGSAL 771 Query: 366 TSPSP---------------MMRSYGGSYPEYSSPSAPPPPPSQ---PQSQAAAAGAAAG 407 + P M SYG +Y P P+ P + +AG A G Sbjct: 772 SPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGG 831 Query: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGR---SQGSPMDPM- 463 MG G M Q + SH +M GP M GS M P Sbjct: 832 ----INPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPP 887 Query: 464 --VMKRPQLYGMGSNPHSQPQQSSP--YP----GGSYGPPGPQRYPIGIQGRTPGAMAGM 515 + ++ Q + + + Q+ P YP GG G P G+ +MAGM Sbjct: 888 GGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPP-------YGQGINSMAGM 940 Query: 516 QYPQ-----------QQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPH 564 PQ +G A E L + G S+ + Sbjct: 941 INPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSS 1000 Query: 565 LPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLS 624 + + + +P++ M + Y ++ A G N + +P L L Sbjct: 1001 STTTNEKITKLYELGGEPERKMWVDRYLAFTEEK-AMGMTNLPAVG----RKPLDLYRLY 1055 Query: 625 GSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHAS---PHLSSIPGGPSPSP 681 S+ ++ T+ + + + G S+ A S + I G P P Sbjct: 1056 VSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPP 1115 Query: 682 ---VGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGT 738 + +Q + P SPA GS PQ P S S S + + P P A T Sbjct: 1116 DIFAAADSKKSQPKIQPPSPAG-SGSMQGPQTPQSTSSSMAEGGDLKPPTP------AST 1168 Query: 739 QRNPQMAQYGPQQTGPSMSPHPSPGGQ---MHAGISSFQQSNS---SGTYGPQMSQYGPQ 792 +Q P P MS S G Q S+FQ+ NS + Y P M+ Sbjct: 1169 PH----SQIPPL---PGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMM 1221 Query: 793 GNYSRPP---AYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNR 849 G S P Y + A S P G N M G S+ G LG + Q+ Sbjct: 1222 GRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGM-GDPYSRAAGP-GLGNVAMGPRQHY 1279 Query: 850 PFPGNMSSMTPSSPGMSQQGGPGMGPPMPTV 880 P+ G + + PG+ +G G P P + Sbjct: 1280 PYGGPYDRVR-TEPGIGPEGNMSTGAPQPNL 1309 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 116 bits (290), Expect = 3e-25 Identities = 241/1007 (23%), Positives = 325/1007 (32%), Gaps = 151/1007 (14%) Query: 59 QQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADP--- 115 Q Q +Q + Q+ P + +G G PQ GP EQ G D G P Sbjct: 24 QGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQ-GPAGEQGPRGDRGDKGEKGAPGPRGR 82 Query: 116 ---------PGPPLLSKPGDEDDAPPKMG-----EPAGGRYEHPGLGALGTQQPPVAV-- 159 PGPP PG PP +G + AGG E G LG Q P+ Sbjct: 83 DGEPGTPGNPGPP--GPPGPP--GPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMG 138 Query: 160 PGGGGGPAAVPEFNNYYGSAA----PASGGPGGRAGPCF-------DQHGGQQSPGMGMM 208 P G GPA P + G+ P GP G GP D G+ Sbjct: 139 PRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERG 198 Query: 209 HSASAAAAGAPGSMD-PLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGG-------- 259 A G PG+ P H GYP PG G G G G Sbjct: 199 PPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEA-GAPGVKGESGSPGENGSPGPMGPR 257 Query: 260 GGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGV---------- 309 G G G G AGA GA A G GG G+ G+ G Sbjct: 258 GLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPE 317 Query: 310 -LSSPRQQGG--------GMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQN--QHPSGAT 358 PR + G G PG G +A G F G P GAT Sbjct: 318 GAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT 377 Query: 359 PTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAG--AAAGGQQAAAGMG 416 L + P + + G P P+ PQ AG G + G+G Sbjct: 378 GPLGPKGQTGEPGIAGFKGEQGPKGEPG-----PAGPQGAPGPAGEEGKRGARGEPGGVG 432 Query: 417 LGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPT-MGRSQGSPMDPMVMKRPQLYG--- 472 G + A + + + P +PG GP+ + +G+ DP P L G Sbjct: 433 PIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARG 492 Query: 473 -MGSNPHSQPQ-----QSSPYPGGSYGPPGPQ--RYPIGIQGRTPGAMAGMQYPQQQDSG 524 G + PQ +P G GPPGPQ R G+ G PG P + Sbjct: 493 LTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMG-FPGPKGANGEPGKAGEK 551 Query: 525 DATWKETFWLMPPQYGQQGVSG-------YCQQGQQ-----PYYSQQPQPPHLPPQAQYL 572 +P + G+ G +G ++G+Q + P PP P + Sbjct: 552 GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEG--- 608 Query: 573 PSQSQQRYQPQQDMSQEGYGTRSQP--PLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDL 630 + + P + + G R + P G P + L + P LP G+ D Sbjct: 609 -GKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGL-----QGPRGLPGTPGT--DG 660 Query: 631 PTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQ 690 P G S G+ G Q P + + A P G P G+P G + Sbjct: 661 PKGA----SGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVG-EKGPEGAP-GKDG 714 Query: 691 SR--SGPISPASIPGSQ------MPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNP 742 R +GPI P G+ PP P GS + ++ P GF + Sbjct: 715 GRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADG 774 Query: 743 QMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYS 802 Q G Q +PG Q +G Q +G GP+ ++ G QG PP + Sbjct: 775 QPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQ--GPTGVTGPKGAR-GAQG----PPGAT 827 Query: 803 GVPSASYSGPGPGMGISANNQMHGQGPSQPCGA-VPLGRMPSAGMQNRPFPGNMSSMTPS 861 G P A+ PG +N GP P G P G +G R G P+ Sbjct: 828 GFPGAAGRVGPPG----SNGNPGPPGPPGPSGKDGPKGARGDSGPPGR--AGEPGLQGPA 881 Query: 862 SPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPY 921 P ++G PG P + A Q + FPG+ P Sbjct: 882 GP-PGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGL--------PGPS 932 Query: 922 SQP-MNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLP 967 +P + + PP + P + A G SPG P Sbjct: 933 GEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREG--SPGADGPP 977 Score = 108 bits (271), Expect = 4e-23 Identities = 179/653 (27%), Positives = 212/653 (32%), Gaps = 103/653 (15%) Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS-KPGDEDDAPPKMGEPA--GG 140 GA G GP E+ + G S G PPGPP KPGD+ P + G P G Sbjct: 570 GAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQG-VPGEAGAPGLVGP 628 Query: 141 RYEHPGLGALGTQQPPVAVPGGGG--GPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHG 198 R E G G+ PG G GP +P P + GP G +GP G Sbjct: 629 RGERGFPGERGS-------PGAQGLQGPRGLP--------GTPGTDGPKGASGPA-GPPG 672 Query: 199 GQQSPGMGMMHSASAAA--AGAPGSM-DPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGG 255 Q PG+ M AA AG G D + EG P G + P G G Sbjct: 673 AQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGR--GLTGPIGPPGPAGA 730 Query: 256 GGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQ 315 G G G G G AGA GA A AG G G G+ G Sbjct: 731 NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGD 790 Query: 316 QGGGMMMGPGGG-GAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRS 374 G GP G G + A G Q G P A Sbjct: 791 AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAA----------------- 833 Query: 375 YGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAA-GGQQAAAGMGLGKDMGAQYAAASPAWA 433 G P S+ + PP P P + GA G AG + G Q A P Sbjct: 834 -GRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAG-----EPGLQGPAGPPGEK 887 Query: 434 AAQQRSHPAMSPGTPGPTMGRSQ----GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPG 489 P+ + G PGP Q G P P L G P +Q +P Sbjct: 888 GEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPG---KQGAPGAS 944 Query: 490 GSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQ 549 G GPPGP P G+ G P G + D P + G GV G Sbjct: 945 GDRGPPGPVGPP-GLTG--PAGEPGREGSPGADGP-----------PGRDGAAGVKGDRG 990 Query: 550 QGQQPYYSQQPQPPHLPPQAQYLPSQSQQ-RYQPQQDMSQEG-YGTRS-QPPLAP----- 601 + P PP P A Q + Q M G G R Q P P Sbjct: 991 ETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKG 1050 Query: 602 --GKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQ 659 G+P L + L L G P G S ASG G + P Sbjct: 1051 EAGEPGERGLK--GHRGFTGLQGLPG-----PPGP----SGDQGASGPAGPSGPRGPPG- 1098 Query: 660 SPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPG 712 P P + IPG P+G P + RSG PA PG+ PP PPG Sbjct: 1099 -PVGPSGKDGANGIPG-----PIGPP--GPRGRSGETGPAGPPGNPGPPGPPG 1143 Score = 106 bits (264), Expect = 3e-22 Identities = 214/848 (25%), Positives = 271/848 (31%), Gaps = 130/848 (15%) Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYE 143 G GG GP E+ G G A P G P + G A PK GR Sbjct: 426 GEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAP--GERGPSGLAGPKGANGDPGRPG 483 Query: 144 HPGL-GALG-TQQPPVAVPGGGGGPAAVPEFNNYYGSAAP--ASGGPG------------ 187 PGL GA G T +P A P G GP+ P + G P A G PG Sbjct: 484 EPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANG 543 Query: 188 --GRAGPCFDQHGGQQSPGMGMM--HSASAAAAGAPGSMDPL-QNSHEGYPN-SQCNHYP 241 G+AG + G +PG+ + AAG PG P + +G P S P Sbjct: 544 EPGKAG----EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLP 599 Query: 242 GYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYG 301 G P GG G G G +G G G G G + A G G G Sbjct: 600 GPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTD 659 Query: 302 GSSAGYGVLSSPRQQGGGMMMG-PGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPT 360 G G P QG + G PG GAA ++ G + G G Sbjct: 660 GPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRG-- 717 Query: 361 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD 420 L + P P G+ E PP P ++ A G AG Sbjct: 718 LTGPIGPPGP-----AGANGE-KGEVGPPGPAGSAGARGAPGERGETGPPGPAGFA---- 767 Query: 421 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ 480 G A P Q + G PGP P P + P+ G+ Sbjct: 768 -GPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPK----GARGAQG 822 Query: 481 PQQSSPYPG--GSYGPPGPQRYPIGIQGRTPGAMAGMQYPQ--QQDSGDATWKETFWLMP 536 P ++ +PG G GPPG P G G P +G P+ + DSG P Sbjct: 823 PPGATGFPGAAGRVGPPGSNGNP-GPPG--PPGPSGKDGPKGARGDSG-----------P 868 Query: 537 P----QYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYG 592 P + G QG +G + +P P PP Q L Q P Q + G+ Sbjct: 869 PGRAGEPGLQGPAGPPGEKGEPG-DDGPSGAEGPPGPQGLAGQRGIVGLPGQ-RGERGFP 926 Query: 593 TRSQPPLAPGKPNHEDLNLIQ-QERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQ 651 P PGK + + P P L+G + G+ + Sbjct: 927 GLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVK 986 Query: 652 GDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPP 711 GD+ P S P GP+ Q GP PA G Q P P Sbjct: 987 GDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPR 1046 Query: 712 GSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGIS 771 G + E+ P ERG GP P P G A Sbjct: 1047 GDKGEAGE---------PGERGLKGHRGFTGLQGLPGP----------PGPSGDQGA--- 1084 Query: 772 SFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHG-QGPS 830 SG GP GP+G PGP +G S + +G GP Sbjct: 1085 -------SGPAGPS----GPRG-----------------PPGP-VGPSGKDGANGIPGPI 1115 Query: 831 QPCGAVPLGRMPSAGMQNRP-FPGNMSSMTPSSPGMSQQGGPGMGP----PMPTVNRKAQ 885 P G P GR G P PG P PG+ G+GP P P +A Sbjct: 1116 GPPG--PRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRAD 1173 Query: 886 EAAAAVMQ 893 +AA + Q Sbjct: 1174 QAAGGLRQ 1181 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 114 bits (286), Expect = 8e-25 Identities = 209/815 (25%), Positives = 263/815 (32%), Gaps = 119/815 (14%) Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGP---PLLSKPGDEDDAPPKMGEPAGG 140 G G PG G A + A G P GP P P E AP G P G Sbjct: 462 GEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAG-PRGA 520 Query: 141 RYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQ 200 E PG + +PG GGP + + P S G GR GP G + Sbjct: 521 AGE-PGRDGVPGGPGMRGMPGSPGGPGSDGK------PGPPGSQGESGRPGPP-GPSGPR 572 Query: 201 QSPG-MGMM----------HSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAG 249 PG MG + G PG P + E P PG + PG Sbjct: 573 GQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGP----PGPTGPGGD 628 Query: 250 GGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGV 309 G G G G G G GG G G A A A GG G G G G+ Sbjct: 629 KGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGL 688 Query: 310 LSSPRQQGGGMMMGP-GGGGAASLSKAAAGSAAGGFQRFAGQ------------------ 350 +P +GG GP GG GAA + G Q G+ Sbjct: 689 AGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGG 748 Query: 351 --------NQHPSGATPTLNQLLTSPSPMMRSYGGS--YPEYSSPSAPPPPPSQPQSQAA 400 P G T + + P + GG+ P + P P + Sbjct: 749 PGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGP 808 Query: 401 AAGAAAGGQQA-AAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSP 459 A A GQ G G G + P A S PA PG G + +GSP Sbjct: 809 AGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQG--VKGERGSP 866 Query: 460 MDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQ 519 P P G+ P S P P GS G GP P G G PG+ G+ P Sbjct: 867 GGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPG-PAGNTG-APGS-PGVSGP- 922 Query: 520 QQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQR 579 + D+G K + P G G G PP +P Sbjct: 923 KGDAGQPGEKGS----PGAQGPPGAPGPLGIAGITGARGLAGPPGMP------------- 965 Query: 580 YQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLS 639 P+ +G S P A G P LP L+G+ + Sbjct: 966 -GPRGSPGPQGVKGESGKPGANGLSGERG-----PPGPQGLPGLAGTAGEPGRDGNPGSD 1019 Query: 640 SAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPS-PSPVGSPVGSNQSR--SGPI 696 GS +GD+ + SP PG P P PVG P G + R SGP Sbjct: 1020 GLPGRDGSPGGKGDRGE--------NGSPGAPGAPGHPGPPGPVG-PAGKSGDRGESGPA 1070 Query: 697 SPASIP---GSQMPPQPPGSQSESSSHPALSQSPMPQERGFMA--GTQRNPQMAQYGPQ- 750 PA P GS+ P P G + + + + RGF G +P GP Sbjct: 1071 GPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSP-----GPAG 1125 Query: 751 QTGPSMSPHPSPGGQMHAGISSFQ-QSNSSGTYGPQMSQYGPQGNYSR-----PPAYSGV 804 Q G SP P+ G + G S + +SG GP + GP+GN P + G Sbjct: 1126 QQGAIGSPGPA-GPRGPVGPSGPPGKDGTSGHPGP-IGPPGPRGNRGERGSEGSPGHPGQ 1183 Query: 805 PS--ASYSGPGPGMGISANNQMHGQGPSQPCGAVP 837 P PGP G + G G + G P Sbjct: 1184 PGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAP 1218 Score = 107 bits (266), Expect = 2e-22 Identities = 221/878 (25%), Positives = 279/878 (31%), Gaps = 151/878 (17%) Query: 65 QQQQQQQQQHPISNNNSLGGAGG---GAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLL 121 Q Q + + + ++GG G A PGP G + G PPG P Sbjct: 149 QNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQ 208 Query: 122 SKPGDEDDAPPKMGE--PAG--GRYEHPGL-GALGTQQPPVAVPGGGGGPAAVPEFNNYY 176 + P P +G PAG G PG G G PP G GPA +P F Sbjct: 209 AGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPP-----GIKGPAGIPGFPGMK 263 Query: 177 GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQ 236 G G GR G + G +PG+ + GAPG M P G P + Sbjct: 264 GHR-----GFDGRNG----EKGETGAPGL-KGENGLPGENGAPGPMGP-----RGAPGER 308 Query: 237 CNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGG 296 RPG G G G G G G G A + A G G Sbjct: 309 -------GRPGLPGAAGA-------RGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVG 354 Query: 297 GGGYGGSSAGYGVLSSPRQQGGGMMMGPGG--------GGAASLSKAAAGSAAG-----G 343 G GS+ G P QG GP G GG + A A G G Sbjct: 355 PAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARG 414 Query: 344 FQRFAGQNQHP----SGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQA 399 AG N P P N P P P P Sbjct: 415 PPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPG 474 Query: 400 AAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGR-SQGS 458 A A G++ A G A P ++ PA G PGP R + G Sbjct: 475 ANGLPGAAGERGAPGF---------RGPAGPNGIPGEK--GPAGERGAPGPAGPRGAAGE 523 Query: 459 PMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGP---PGPQRYPIGIQGRTPGAMAGM 515 P V P + GM +P P P GS G PGP P G +G+ PG M Sbjct: 524 PGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPG-PSGPRGQ-PGVMG-- 579 Query: 516 QYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQ 575 +P + + A K P G QG G + G+ PQ P P P Sbjct: 580 -FPGPKGNDGAPGKNGERGGPGGPGPQGPPG--KNGE-----TGPQGPPGPTG----PGG 627 Query: 576 SQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTE 635 + P +G PP GKP + + P G D E Sbjct: 628 DKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPG-----PKGDAGAPGAPGGKGDAGAPGE 682 Query: 636 ---ATLSSAVSASGSTSSQGDQ--SNPAQSPFSPHA--SPHLSSIPG-----------GP 677 L+ A G G + A P P A +P L +PG G Sbjct: 683 RGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGD 742 Query: 678 SPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAG 737 P G + GP P G P PG + E + P L +AG Sbjct: 743 KGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGA-PGLPG---------IAG 792 Query: 738 TQRNP-QMAQYGPQQTGPSMSP-----HPSPGGQMHAGISSFQ-QSNSSGTYGPQMSQYG 790 + +P + + GP GP+ P + PGG+ G + + G GP G Sbjct: 793 PRGSPGERGETGP--PGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGS-G 849 Query: 791 PQGNYSRPPAYSGVPSASYSGPGPG-MGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNR 849 P G PP GV S GPG G + G P P G S G Sbjct: 850 PAG----PPGPQGVKGERGSPGGPGAAGFPGARGLPGP-PGSNGNPGPPGPSGSPGKDGP 904 Query: 850 PFPGNMSSMTPSSPGMS----------QQGGPG-MGPP 876 P P ++ P SPG+S ++G PG GPP Sbjct: 905 PGPAG-NTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPP 941 Score = 77.4 bits (189), Expect = 1e-13 Identities = 180/778 (23%), Positives = 240/778 (30%), Gaps = 127/778 (16%) Query: 160 PGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAP 219 P G GP +P N G P G G GP PG+ + P Sbjct: 107 PKGDPGPPGIPGRNGDPG--IPGQPGSPGSPGP----------PGI------CESCPTGP 148 Query: 220 GSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAG 279 + P +S++ GY P G G G G G G G G G Sbjct: 149 QNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQ 208 Query: 280 AVAAAAAAAAAAAGGGGGGGYGGSS------AGYGVLSSPRQQGGGMMMG-PGGGGAASL 332 A + A G G G G S G+ P +G + G PG G Sbjct: 209 AGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGF 268 Query: 333 SKAAAGSAAGGFQRFAGQN-----------QHPSGATPTLNQLLTSPSPMMRSYGGSYPE 381 G G+N P GA + + R G+ Sbjct: 269 DGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGS 328 Query: 382 YSSPSAPPPP-----PSQPQSQAAAAGAAAGGQQAAAGM----GLGKDMGAQYAAASP-- 430 P P PP P P ++ A + G A G G GAQ P Sbjct: 329 DGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGI 388 Query: 431 -AWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPG 489 + PA PG PG R P G P + P Sbjct: 389 NGSPGGKGEMGPAGIPGAPGLMGARGPPGPA-----------GANGAPGLRGGAGEPGKN 437 Query: 490 GSYGPPGP--QRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGY 547 G+ G PGP +R GI G PGA + +D D + P + G G+ G Sbjct: 438 GAKGEPGPRGERGEAGIPG-VPGA-------KGEDGKDGS--------PGEPGANGLPGA 481 Query: 548 CQQGQQPYYSQQPQPPHLPPQ-----AQYLPSQSQQR---YQPQQDMSQEGYGTRSQP-- 597 + P + P +P + + P + R +P +D G G R P Sbjct: 482 AGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGS 541 Query: 598 ---PLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLS--SAVSASGSTSSQG 652 P + GKP + + RP P SG P G + G+ G Sbjct: 542 PGGPGSDGKPGPPG-SQGESGRPGP-PGPSG-----PRGQPGVMGFPGPKGNDGAPGKNG 594 Query: 653 DQSNP-AQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPP 711 ++ P P P + G P P+ G G + GP +PG+ PP Sbjct: 595 ERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKG-DTGPPGPQGLQGLPGTGGPPGEN 653 Query: 712 GSQSESSSHPALSQSPMPQERGFM-AGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGI 770 G E P +G A +R P P G + P P GG+ AG Sbjct: 654 GKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPE-GGKGAAGP 712 Query: 771 SSFQQSNSSGTYGPQ--------MSQYGPQGNYSRP--PAYSGVPS----ASYSGP--GP 814 ++GT G Q + GP+G+ P P GVP +GP P Sbjct: 713 PG--PPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPP 770 Query: 815 GMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPG 872 G ++ G P P A P G G P P P +PG Q G PG Sbjct: 771 GPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGF----PGAPG--QNGEPG 822 Score = 77.4 bits (189), Expect = 1e-13 Identities = 110/363 (30%), Positives = 127/363 (34%), Gaps = 43/363 (11%) Query: 82 LGGAGGGAPQPGPDMEQPQHGGAKDSAAG--GQADPPGPPLLSKPGDEDDAPPKMGEP-A 138 L G G PGP P KD G G PG P +S P + P + G P A Sbjct: 880 LPGPPGSNGNPGPP--GPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGA 937 Query: 139 GGRYEHPG-LGALG-TQQPPVAVPGGGGGPAAVPEFNNYYG-SAAPASGGPGGRAGPCFD 195 G PG LG G T +A P G GP P G S P + G G GP Sbjct: 938 QGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGP--- 994 Query: 196 QHGGQQSPGMGMMHSASAAAAGAPGS--MDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGG 253 G Q PG+ + G PGS + S G + N PG PGA G G Sbjct: 995 -PGPQGLPGLAGT-AGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPG--APGAPGHPG 1050 Query: 254 GGG--GGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLS 311 G G G SG G G AG GA A + A G G G G++ G Sbjct: 1051 PPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRG 1110 Query: 312 SPRQQGGGMMMGPGGGGAASLSKAAAGSAA----GGFQRFAGQNQHPSGATPTLNQLLTS 367 P G GP G A S AG G G + HP P Sbjct: 1111 FPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGP-------- 1162 Query: 368 PSPM----MRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGA 423 P P R GS P + PP PP P G GG AAA G+G + Sbjct: 1163 PGPRGNRGERGSEGS-PGHPGQPGPPGPPGAP-------GPCCGGVGAAAIAGIGGEKAG 1214 Query: 424 QYA 426 +A Sbjct: 1215 GFA 1217 Score = 63.9 bits (154), Expect = 2e-09 Identities = 89/334 (26%), Positives = 115/334 (34%), Gaps = 59/334 (17%) Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLL-------SKPGDE-----DDAP 131 G G PGP + + G + G+ PPGP L +PG + D P Sbjct: 963 GMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLP 1022 Query: 132 PKMGEPAG--GRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASG-GPGG 188 + G P G R E+ GA G P P G GPA G A PA GP G Sbjct: 1023 GRDGSPGGKGDRGENGSPGAPGAPGHPG--PPGPVGPAGKSGDRGESGPAGPAGAPGPAG 1080 Query: 189 RAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGA 248 G G Q P + AAG G H G+P + PGA Sbjct: 1081 SRGA-----PGPQGPRGDKGETGERGAAGIKG--------HRGFPGN----------PGA 1117 Query: 249 GGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYG 308 G G G G G G AG G + + G G G G+ G Sbjct: 1118 PGSPGPAGQ----QGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERG 1173 Query: 309 VLSSPRQQGGGMMMGP--------GGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPT 360 SP G GP GG GAA+++ G AGGF + G P Sbjct: 1174 SEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIA-GIGGEKAGGFAPYYG--DEPMDFKIN 1230 Query: 361 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQ 394 ++++TS ++S G SP P++ Sbjct: 1231 TDEIMTS----LKSVNGQIESLISPDGSRKNPAR 1260 Score = 59.7 bits (143), Expect = 3e-08 Identities = 95/400 (23%), Positives = 127/400 (31%), Gaps = 79/400 (19%) Query: 560 PQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSS 619 PQPP P + P Q P+ D G R+ P PG+P P S Sbjct: 89 PQPPTAPTR----PPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPG----------SPGS 134 Query: 620 LPDLSGSIDDLPTGTE--------ATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLS 671 P G + PTG + + S V+ G G PA P P P S Sbjct: 135 -PGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPG----PAGPP-GPPGPPGTS 188 Query: 672 SIPGGP-SPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESS--SHPALSQSP- 727 PG P SP G P ++GP P PG+ P P G ES P P Sbjct: 189 GHPGSPGSPGYQGPP--GEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPG 246 Query: 728 ------------MPQERGFMAGTQRNPQMAQYG----------PQQTGP--SMSPHPSPG 763 P +G RN + + G P + G M P +PG Sbjct: 247 PPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPG 306 Query: 764 GQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSA--SYSGPGPGMGISAN 821 + G+ + + Q GP G PP +G P + + GP +N Sbjct: 307 ERGRPGLPGAAGARGNDGARGSDGQPGPPG----PPGTAGFPGSPGAKGEVGPAGSPGSN 362 Query: 822 NQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPG-------MG 874 +G P G AG Q P P ++ M G PG G Sbjct: 363 GAPGQRGEPGPQG--------HAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARG 414 Query: 875 PPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGL 914 PP P A + N A+ G ++G+ Sbjct: 415 PPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGI 454 Score = 57.0 bits (136), Expect = 2e-07 Identities = 66/226 (29%), Positives = 79/226 (34%), Gaps = 28/226 (12%) Query: 79 NNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGP-PLLSKPGDEDDAPPKMGEP 137 N G G PG ++ ++G A G PPGP K GD ++ P P Sbjct: 1015 NPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGP--AGP 1072 Query: 138 AGGRYEHPGLGALGTQQP-PVAVPGGGGGPAAVPEFNNYYGS-AAPASGGPGGRAGPCFD 195 AG GA G Q P G G A + + G+ AP S GP G Sbjct: 1073 AGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAG------- 1125 Query: 196 QHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQ-CNHYPGYSRPGAGGGGGG 254 Q G SPG AG G + P G P + +PG P G G Sbjct: 1126 QQGAIGSPG----------PAGPRGPVGP-----SGPPGKDGTSGHPGPIGPPGPRGNRG 1170 Query: 255 GGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY 300 G G G G G G GA AAA A GG GG+ Sbjct: 1171 ERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGF 1216 Score = 55.5 bits (132), Expect = 6e-07 Identities = 63/223 (28%), Positives = 70/223 (31%), Gaps = 38/223 (17%) Query: 80 NSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAG 139 N GA G PGP G + D G A P G P P AP G P G Sbjct: 1037 NGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAP---GPAGSRGAPGPQG-PRG 1092 Query: 140 GRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGG 199 + E GA G + PG G P + +P GP G GP Sbjct: 1093 DKGETGERGAAGIKGHR-GFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGP------- 1144 Query: 200 QQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGG 259 PG +G PG + P PG P G G G Sbjct: 1145 SGPPG-------KDGTSGHPGPIGP----------------PG---PRGNRGERGSEGSP 1178 Query: 260 GGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG 302 G G G G GA G G V AAA A GG Y G Sbjct: 1179 GHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYYG 1221 Score = 33.9 bits (76), Expect = 1.8 Identities = 37/129 (28%), Positives = 44/129 (34%), Gaps = 13/129 (10%) Query: 76 ISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMG 135 I + G G PGP +Q G + G P GPP K G P +G Sbjct: 1105 IKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPP--GKDGTSGH-PGPIG 1161 Query: 136 EPA--GGRYEHPGLGALG-TQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGP 192 P G R E G+ G QP P G GP G A A G GG Sbjct: 1162 PPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCC-------GGVGAAAIAGIGGEKAG 1214 Query: 193 CFDQHGGQQ 201 F + G + Sbjct: 1215 GFAPYYGDE 1223 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 113 bits (283), Expect = 2e-24 Identities = 238/995 (23%), Positives = 320/995 (32%), Gaps = 151/995 (15%) Query: 71 QQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADP------------PGP 118 Q+ P + +G G PQ GP EQ G D G P PGP Sbjct: 105 QKGEPGDIKDIVGPKGPPGPQ-GPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGP 163 Query: 119 PLLSKPGDEDDAPPKMG-----EPAGGRYEHPGLGALGTQQPPVAV--PGGGGGPAAVPE 171 P PG PP +G + AGG E G LG Q P+ P G GPA P Sbjct: 164 P--GPPGPP--GPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPG 219 Query: 172 FNNYYGSAA----PASGGPGGRAGPCF-------DQHGGQQSPGMGMMHSASAAAAGAPG 220 + G+ P GP G GP D G+ A G PG Sbjct: 220 PQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPG 279 Query: 221 SMD-PLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGG--------GGSGGGGGGGGA 271 + P H GYP PG G G G G G G G G A Sbjct: 280 TPGLPGVKGHRGYPGLDGAKGEA-GAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPA 338 Query: 272 GAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGV-----------LSSPRQQGG-- 318 GA GA A G GG G+ G+ G PR + G Sbjct: 339 GAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTP 398 Query: 319 ------GMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQN--QHPSGATPTLNQLLTSPSP 370 G PG G +A G F G P GAT L + P Sbjct: 399 GSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEP 458 Query: 371 MMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAG--AAAGGQQAAAGMGLGKDMGAQYAAA 428 + + G P P+ PQ AG G + G+G G + A Sbjct: 459 GIAGFKGEQGPKGEPG-----PAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPG 513 Query: 429 SPAWAAAQQRSHPAMSPGTPGPT-MGRSQGSPMDPMVMKRPQLYG----MGSNPHSQPQ- 482 + + + P +PG GP+ + +G+ DP P L G G + PQ Sbjct: 514 NRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQG 573 Query: 483 ----QSSPYPGGSYGPPGPQ--RYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMP 536 +P G GPPGPQ R G+ G PG P + +P Sbjct: 574 KVGPSGAPGEDGRPGPPGPQGARGQPGVMG-FPGPKGANGEPGKAGEKGLPGAPGLRGLP 632 Query: 537 PQYGQQGVSG-------YCQQGQQ-----PYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQ 584 + G+ G +G ++G+Q + P PP P + + + P + Sbjct: 633 GKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEG----GKPGDQGVPGE 688 Query: 585 DMSQEGYGTRSQP--PLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAV 642 + G R + P G P + L + P LP G+ D P G S Sbjct: 689 AGAPGLVGPRGERGFPGERGSPGAQGL-----QGPRGLPGTPGT--DGPKGA----SGPA 737 Query: 643 SASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSR--SGPISPAS 700 G+ G Q P + + A P G P G+P G + R +GPI P Sbjct: 738 GPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVG-EKGPEGAP-GKDGGRGLTGPIGPPG 795 Query: 701 IPGSQ------MPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGP 754 G+ PP P GS + ++ P GF + Q G Q Sbjct: 796 PAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAG 855 Query: 755 SMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGP 814 +PG Q +G Q +G GP+ ++ G QG PP +G P A+ P Sbjct: 856 QKGDAGAPGPQGPSGAPGPQ--GPTGVTGPKGAR-GAQG----PPGATGFPGAAGRVGPP 908 Query: 815 GMGISANNQMHGQGPSQPCGA-VPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGM 873 G +N GP P G P G +G R G P+ P ++G PG Sbjct: 909 G----SNGNPGPPGPPGPSGKDGPKGARGDSGPPGR--AGEPGLQGPAGP-PGEKGEPGD 961 Query: 874 GPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQP-MNNSSSLM 932 P + A Q + FPG+ P +P + Sbjct: 962 DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGL--------PGPSGEPGKQGAPGAS 1013 Query: 933 NTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLP 967 + PP + P + A G SPG P Sbjct: 1014 GDRGPPGPVGPPGLTGPAGEPGREG--SPGADGPP 1046 Score = 108 bits (271), Expect = 4e-23 Identities = 179/653 (27%), Positives = 212/653 (32%), Gaps = 103/653 (15%) Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS-KPGDEDDAPPKMGEPA--GG 140 GA G GP E+ + G S G PPGPP KPGD+ P + G P G Sbjct: 639 GAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQG-VPGEAGAPGLVGP 697 Query: 141 RYEHPGLGALGTQQPPVAVPGGGG--GPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHG 198 R E G G+ PG G GP +P P + GP G +GP G Sbjct: 698 RGERGFPGERGS-------PGAQGLQGPRGLP--------GTPGTDGPKGASGPA-GPPG 741 Query: 199 GQQSPGMGMMHSASAAA--AGAPGSM-DPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGG 255 Q PG+ M AA AG G D + EG P G + P G G Sbjct: 742 AQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGR--GLTGPIGPPGPAGA 799 Query: 256 GGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQ 315 G G G G G AGA GA A AG G G G+ G Sbjct: 800 NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGD 859 Query: 316 QGGGMMMGPGGG-GAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRS 374 G GP G G + A G Q G P A Sbjct: 860 AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAA----------------- 902 Query: 375 YGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAA-GGQQAAAGMGLGKDMGAQYAAASPAWA 433 G P S+ + PP P P + GA G AG + G Q A P Sbjct: 903 -GRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAG-----EPGLQGPAGPPGEK 956 Query: 434 AAQQRSHPAMSPGTPGPTMGRSQ----GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPG 489 P+ + G PGP Q G P P L G P +Q +P Sbjct: 957 GEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPG---KQGAPGAS 1013 Query: 490 GSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQ 549 G GPPGP P G+ G P G + D P + G GV G Sbjct: 1014 GDRGPPGPVGPP-GLTG--PAGEPGREGSPGADGP-----------PGRDGAAGVKGDRG 1059 Query: 550 QGQQPYYSQQPQPPHLPPQAQYLPSQSQQ-RYQPQQDMSQEG-YGTRS-QPPLAP----- 601 + P PP P A Q + Q M G G R Q P P Sbjct: 1060 ETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKG 1119 Query: 602 --GKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQ 659 G+P L + L L G P G S ASG G + P Sbjct: 1120 EAGEPGERGLK--GHRGFTGLQGLPG-----PPGP----SGDQGASGPAGPSGPRGPPG- 1167 Query: 660 SPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPG 712 P P + IPG P+G P + RSG PA PG+ PP PPG Sbjct: 1168 -PVGPSGKDGANGIPG-----PIGPP--GPRGRSGETGPAGPPGNPGPPGPPG 1212 Score = 106 bits (264), Expect = 3e-22 Identities = 214/848 (25%), Positives = 271/848 (31%), Gaps = 130/848 (15%) Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYE 143 G GG GP E+ G G A P G P + G A PK GR Sbjct: 495 GEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAP--GERGPSGLAGPKGANGDPGRPG 552 Query: 144 HPGL-GALG-TQQPPVAVPGGGGGPAAVPEFNNYYGSAAP--ASGGPG------------ 187 PGL GA G T +P A P G GP+ P + G P A G PG Sbjct: 553 EPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANG 612 Query: 188 --GRAGPCFDQHGGQQSPGMGMM--HSASAAAAGAPGSMDPL-QNSHEGYPN-SQCNHYP 241 G+AG + G +PG+ + AAG PG P + +G P S P Sbjct: 613 EPGKAG----EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLP 668 Query: 242 GYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYG 301 G P GG G G G +G G G G G + A G G G Sbjct: 669 GPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTD 728 Query: 302 GSSAGYGVLSSPRQQGGGMMMG-PGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPT 360 G G P QG + G PG GAA ++ G + G G Sbjct: 729 GPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRG-- 786 Query: 361 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD 420 L + P P G+ E PP P ++ A G AG Sbjct: 787 LTGPIGPPGP-----AGANGE-KGEVGPPGPAGSAGARGAPGERGETGPPGPAGFA---- 836 Query: 421 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ 480 G A P Q + G PGP P P + P+ G+ Sbjct: 837 -GPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPK----GARGAQG 891 Query: 481 PQQSSPYPG--GSYGPPGPQRYPIGIQGRTPGAMAGMQYPQ--QQDSGDATWKETFWLMP 536 P ++ +PG G GPPG P G G P +G P+ + DSG P Sbjct: 892 PPGATGFPGAAGRVGPPGSNGNP-GPPG--PPGPSGKDGPKGARGDSG-----------P 937 Query: 537 P----QYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYG 592 P + G QG +G + +P P PP Q L Q P Q + G+ Sbjct: 938 PGRAGEPGLQGPAGPPGEKGEPG-DDGPSGAEGPPGPQGLAGQRGIVGLPGQ-RGERGFP 995 Query: 593 TRSQPPLAPGKPNHEDLNLIQ-QERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQ 651 P PGK + + P P L+G + G+ + Sbjct: 996 GLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVK 1055 Query: 652 GDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPP 711 GD+ P S P GP+ Q GP PA G Q P P Sbjct: 1056 GDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPR 1115 Query: 712 GSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGIS 771 G + E+ P ERG GP P P G A Sbjct: 1116 GDKGEAGE---------PGERGLKGHRGFTGLQGLPGP----------PGPSGDQGA--- 1153 Query: 772 SFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHG-QGPS 830 SG GP GP+G PGP +G S + +G GP Sbjct: 1154 -------SGPAGPS----GPRG-----------------PPGP-VGPSGKDGANGIPGPI 1184 Query: 831 QPCGAVPLGRMPSAGMQNRP-FPGNMSSMTPSSPGMSQQGGPGMGP----PMPTVNRKAQ 885 P G P GR G P PG P PG+ G+GP P P +A Sbjct: 1185 GPPG--PRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRAD 1242 Query: 886 EAAAAVMQ 893 +AA + Q Sbjct: 1243 QAAGGLRQ 1250 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 113 bits (282), Expect = 2e-24 Identities = 243/968 (25%), Positives = 310/968 (32%), Gaps = 182/968 (18%) Query: 88 GAPQP----GPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYE 143 GAP P GP E + G S G PPGPP K GD+ +A G+P Sbjct: 194 GAPGPQGFQGPPGEPGEPGA---SGPMGPRGPPGPP--GKNGDDGEA----GKP------ 238 Query: 144 HPGLGALGTQQPPVAVPGGG-GGPAAVPEFNNYYG-SAAPASGGPGGRAGPCFDQHGGQQ 201 G G + PP G G A +P + G S + G G AGP G Sbjct: 239 ----GRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGP----KGEPG 290 Query: 202 SPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGG--GGGGGGGGG 259 SPG GAPG M P G P + RPGA G G G G Sbjct: 291 SPGEN----------GAPGQMGP-----RGLPGER-------GRPGAPGPAGARGNDGAT 328 Query: 260 GGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGG 319 G +G G G AG G A A G G G GS GV P G Sbjct: 329 GAAGPPGPTGPAGPPG---------FPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPA 379 Query: 320 MMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYG--- 376 GP G A A G A G AG P P+ Q P + G Sbjct: 380 GAAGPAGNPGADGQPGAKG--ANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPG 437 Query: 377 --GSYPEYSSPSAPPPPPSQ-PQSQAAAAG-AAAGGQQAAAGM-GLGKDMGAQYAAASPA 431 GS + + P P Q P A G A G+ G+ G + G + P Sbjct: 438 APGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPG 497 Query: 432 WAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGS 491 PA G+PGP G P RP G+ SP P G Sbjct: 498 ADGVAGPKGPAGERGSPGPA-----GPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGK 552 Query: 492 YGPPGPQRYPIGIQGR-----TPGA--MAG-MQYPQQQDSGDATWKETFWLMPPQYGQQG 543 GPPG P G GR PGA AG M +P + + P + G++G Sbjct: 553 TGPPG----PAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGE---------PGKAGERG 599 Query: 544 VSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGK 603 V G G + + P P+ + P +G + PP GK Sbjct: 600 VPG--PPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGK 657 Query: 604 PNHEDLNLIQQERPSSL--PDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSN----- 656 P +Q P L P SG+ + E + +G + G N Sbjct: 658 PG-------EQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKG 710 Query: 657 PAQSPFSP--HASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQ--------- 705 A +P +P +P L +PG + + P G ++ +GP PG Sbjct: 711 DAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKG-DRGDAGPKGADGSPGKDGVRGLTGPI 769 Query: 706 MPPQP---PGSQSESS-SHPA--LSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPH 759 PP P PG + ES S PA P +RG + GP Sbjct: 770 GPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRG---------EPGPPGPAGFAGPPGAD 820 Query: 760 PSPGGQMHAGISSFQ-QSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSG----PGP 814 PG + G + + + G GP GP GN P A SA G PG Sbjct: 821 GQPGAKGEPGDAGAKGDAGPPGPAGP-AGPPGPIGNVGAPGAKGARGSAGPPGATGFPGA 879 Query: 815 GMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMT--PSSPG-MSQQGGP 871 + GP P G P G+ G + P P PG ++G P Sbjct: 880 AGRVGPPGPSGNAGPPGPPG--PAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSP 937 Query: 872 GMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQP-MNNSSS 930 G P + A Q + FPG+ P +P S Sbjct: 938 GADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGL--------PGPSGEPGKQGPSG 989 Query: 931 LMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSS 990 + PP M P GLA PGES EG P E + Sbjct: 990 ASGERGPPGPMGPP---------GLAG--PPGES----------GREGAPGAEGSPGRDG 1028 Query: 991 SSTTTGEK 998 S G++ Sbjct: 1029 SPGAKGDR 1036 Score = 108 bits (270), Expect = 6e-23 Identities = 222/885 (25%), Positives = 276/885 (31%), Gaps = 164/885 (18%) Query: 73 QHPISNNNSLGGAGGGAPQ--PGPDMEQPQHGGAKDSAAGGQADPPGPP----------- 119 Q P G +G P+ PGP + G A G+ PPGP Sbjct: 202 QGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGL 261 Query: 120 -----------LLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAA 168 L GD A PK GEP PG Q P +PG G P A Sbjct: 262 PGMKGHRGFSGLDGAKGDAGPAGPK-GEPGS-----PGENGAPGQMGPRGLPGERGRPGA 315 Query: 169 VPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNS 228 A + GP G GP G PG A GA G P Sbjct: 316 PGPAGARGNDGATGAAGPPGPTGPA----GPPGFPG----------AVGAKGEAGPQGPR 361 Query: 229 HEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAA 288 P G P G G G G G G G GA G A Sbjct: 362 GSEGPQG----VRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGP 417 Query: 289 AAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFA 348 + G GG G G+S G S G GP G + G A +R A Sbjct: 418 SGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVG------VQGPPGPAGEEGKRGA 471 Query: 349 GQNQHPSGATPTLNQLLTSPSPMMRSYGGS--YPEYSSPSAPPPPPSQPQSQAAAAGAAA 406 P+G L P P R GS +P + P P + S A + Sbjct: 472 RGEPGPTG--------LPGP-PGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGS 522 Query: 407 GGQQAAAG-MGLGKDMGAQYAAASPAWAAAQQRSHPAMS---PGTPGPTMGRSQGSPMDP 462 G+ G GL G + SP PA PG PGP R Q Sbjct: 523 PGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAG---- 578 Query: 463 MVMKRPQLYGMGSNPHSQPQQSSPYP------------GGSYGPPGPQRYPIGIQG-RTP 509 VM P G P ++ P P G+ GPPGP P G +G + P Sbjct: 579 -VMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAG-PAGERGEQGP 636 Query: 510 GAMAGMQ-YPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYS----QQPQPPH 564 G Q P K +P G G SG +G++ + Q P P Sbjct: 637 AGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSG--ARGERGFPGERGVQGPPGPA 694 Query: 565 LPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQER-PSSLPDL 623 P A P +G + P APG L + ER + LP Sbjct: 695 GPRGANGAP-------------GNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGP 741 Query: 624 SGSIDDL-PTGTEAT--------LSSAVSASGSTSSQGDQ-----SNPAQSPFSPHASPH 669 G D P G + + L+ + G + GD+ S PA P +P Sbjct: 742 KGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPA-GPTGARGAPG 800 Query: 670 LSSIPGGPSPSPVGSPVGSN--------------QSRSGPISPASIPGSQMPPQPPGSQS 715 PG P P+ P G++ + +GP PA G PP P G+ Sbjct: 801 DRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAG---PPGPIGNVG 857 Query: 716 ESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQ 775 + A + P GF R GP GPS + P PG AG Sbjct: 858 APGAKGARGSAGPPGATGFPGAAGR------VGP--PGPSGNAGP-PGPPGPAG------ 902 Query: 776 SNSSGTYGPQMSQYGPQGNYSR--PPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPC 833 G GP+ + GP G PP G P+ PG A QG + Sbjct: 903 --KEGGKGPR-GETGPAGRPGEVGPPGPPG-PAGEKGSPGADGPAGAPGTPGPQGIAGQR 958 Query: 834 GAVPL-GRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPG-MGPP 876 G V L G+ G P P S ++G PG MGPP Sbjct: 959 GVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPP 1003 Score = 104 bits (259), Expect = 1e-21 Identities = 183/684 (26%), Positives = 218/684 (31%), Gaps = 117/684 (17%) Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPP-LLSKPGDEDDAPPKMGEP--AGG 140 GA G GP E+ + G A G P GPP KPG E P +G P +G Sbjct: 617 GAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPG-EQGVPGDLGAPGPSGA 675 Query: 141 RYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQ 200 R E G G Q PP P G G P + G A A G PG + P G Q Sbjct: 676 RGERGFPGERGVQGPPG--PAGPRGANGAPGNDGAKGDAG-APGAPGSQGAP-----GLQ 727 Query: 201 QSPGMGMMHSASAAAAGAPGSM----DPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGG 256 PG AAG PG D +G P + G + P G G Sbjct: 728 GMPG-------ERGAAGLPGPKGDRGDAGPKGADGSPGK--DGVRGLTGPIGPPGPAGAP 778 Query: 257 GGGGGSGGGGGGGGAGAGGAGAGAVA------AAAAAAAAAAGGGGGGGYGGSSAGYGVL 310 G G SG G G GA GA A A A G G G G + G Sbjct: 779 GDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDA 838 Query: 311 SSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGAT--PTLNQLLTSP 368 P G GP G A +K A GSA P GAT P + P Sbjct: 839 GPPGPAGPAGPPGPIGNVGAPGAKGARGSAG------------PPGATGFPGAAGRVGPP 886 Query: 369 SPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAA 428 P S +A PP P P + G G+ AG + Sbjct: 887 GP-------------SGNAGPPGPPGPAGKEGGKGPR--GETGPAGRP------GEVGPP 925 Query: 429 SPAWAAAQQRSH----PAMSPGTPGPTMGRSQ----GSPMDPMVMKRPQLYGMGSNPHSQ 480 P A ++ S PA +PGTPGP Q G P P L G P Q Sbjct: 926 GPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQ 985 Query: 481 PQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYG 540 + G GPPGP P G+ G PG P + S P + G Sbjct: 986 GPSGA---SGERGPPGPMGPP-GLAG-PPGESGREGAPGAEGS------------PGRDG 1028 Query: 541 QQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQP--P 598 G G + P PP A P P + G + P P Sbjct: 1029 SPGAKG----------DRGETGPAGPPGAPGAPGAPG----PVGPAGKSGDRGETGPAGP 1074 Query: 599 LAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQS-NP 657 P P + P +G D S G S G+Q + Sbjct: 1075 AGPVGPVGAR-GPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSG 1133 Query: 658 AQSPFSPHASPHLSSIPGGPS----PSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGS 713 A P P P + PG P P+G P + R+G P PG PP PPG Sbjct: 1134 ASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPP--GPRGRTGDAGPVGPPGPPGPPGPPGP 1191 Query: 714 QSESSSHPALSQSPMPQERGFMAG 737 S L Q PQE+ G Sbjct: 1192 PSAGFDFSFLPQP--PQEKAHDGG 1213 Score = 90.5 bits (223), Expect = 2e-17 Identities = 183/728 (25%), Positives = 224/728 (30%), Gaps = 147/728 (20%) Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPP-------LLSKPGDEDDA--PPKM 134 G G PGPD + G A G+ PPGPP ++ PG + A P K Sbjct: 539 GLTGSPGSPGPDGKTGPPGPAGQD---GRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA 595 Query: 135 GE-----PAGGRYEHPGLGALGTQQPP----VAVPGGGGGPAAVPEFNNYYGSAAPASGG 185 GE P G G G Q PP A G GPA P F G A G Sbjct: 596 GERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPA-----G 650 Query: 186 PGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSR 245 P G AG + G Q PG GAPG G+P + G Sbjct: 651 PPGEAG----KPGEQGVPG----------DLGAPGPSGA--RGERGFPGER-----GVQG 689 Query: 246 PGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSA 305 P G G G G G G G GA G+ AAG G G G + Sbjct: 690 PPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAG 749 Query: 306 GYGVLSSPRQQGGGMMMGPGG-----GGAASLSKAAAGSAAG--GFQRFAGQNQHPSGAT 358 G SP + G + GP G G ++ AG G + G P Sbjct: 750 PKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPG 809 Query: 359 PTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAG--AAAGGQQAAAGMG 416 P + G + A PP P+ P G A G + A G Sbjct: 810 PAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAG 869 Query: 417 LGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSN 476 G AA + P PG G G+ P RP G Sbjct: 870 PPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPA--GRPGEVGPPGP 927 Query: 477 PHSQPQQSSPY---PGGSYGPPGPQ-----RYPIGIQG-RTPGAMAGMQYPQQQDSGDAT 527 P ++ SP P G+ G PGPQ R +G+ G R G+ P SG+ Sbjct: 928 PGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGP----SGE-- 981 Query: 528 WKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRY------Q 581 P + G G SG + P P PP P +S + Sbjct: 982 --------PGKQGPSGASG----------ERGPPGPMGPPGLAGPPGESGREGAPGAEGS 1023 Query: 582 PQQDMSQEGYGTRSQ-----PPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDL----PT 632 P +D S G R + PP APG P P SG + P Sbjct: 1024 PGRDGSPGAKGDRGETGPAGPPGAPGAPGAPG--------PVGPAGKSGDRGETGPAGPA 1075 Query: 633 GTEATLSSAVSAS--------GSTSSQGDQS-----------NPAQSPFSP-HASPHLSS 672 G + + A G T QGD+ P P SP P +S Sbjct: 1076 GPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGAS 1135 Query: 673 IPGGPS--PSPVGSP----VGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQS 726 P GP P G+P + GP P G P PPG P Sbjct: 1136 GPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGP-------PGPPGP 1188 Query: 727 PMPQERGF 734 P P GF Sbjct: 1189 PGPPSAGF 1196 Score = 85.5 bits (210), Expect = 5e-16 Identities = 112/426 (26%), Positives = 135/426 (31%), Gaps = 36/426 (8%) Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPP-LLSKPGDEDDAPPKMGEPAGGRY 142 G G A PG D + G D+ A G A PPGP PG + + A G Sbjct: 809 GPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSA 868 Query: 143 EHPGL----GALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAP-ASGGPGGRAGPCFDQH 197 PG GA G PP P G GP P G P GP GR G + Sbjct: 869 GPPGATGFPGAAGRVGPPG--PSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPG----EV 922 Query: 198 GGQQSPGMGMMHSASAA--AAGAPGSMDPL----QNSHEGYPNSQCNH-YPGYSRPGAGG 250 G PG + A AGAPG+ P Q G P + +PG P Sbjct: 923 GPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEP 982 Query: 251 GGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVL 310 G G G G G G G G G + A A + G G G G G Sbjct: 983 GKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPA 1042 Query: 311 SSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSP 370 P G GP G S + G A + P+G + Sbjct: 1043 GPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQ 1102 Query: 371 MMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGM--GLGKD--MGAQYA 426 R G + +S PP PP P Q + + G + G GKD G Sbjct: 1103 GDRGIKG-HRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGP 1161 Query: 427 AASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSP 486 P + P PG PGP G P P G + QP Q Sbjct: 1162 IGPPGPRGRTGDAGPVGPPGPPGP-----PGPPGPPSA-------GFDFSFLPQPPQEKA 1209 Query: 487 YPGGSY 492 + GG Y Sbjct: 1210 HDGGRY 1215 Score = 65.9 bits (159), Expect = 4e-10 Identities = 167/672 (24%), Positives = 218/672 (32%), Gaps = 122/672 (18%) Query: 373 RSYGG-SYPEYSSPSAP---PPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAA 428 +S GG S P PS P P PP P Q G+ A+G MG + Sbjct: 170 KSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASG-----PMGPR---G 221 Query: 429 SPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYP 488 P A PG PG +G P P G+ + Sbjct: 222 PPGPPGKNGDDGEAGKPGRPG-----ERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGA 276 Query: 489 GGSYGPPGPQRYPIGIQGR--TPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSG 546 G GP GP+ P G G PG M P ++ A P G +G G Sbjct: 277 KGDAGPAGPKGEP-GSPGENGAPGQMGPRGLPGERGRPGA---------PGPAGARGNDG 326 Query: 547 YCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEG-YGTRSQPPLAPGKPN 605 P + PP P ++ PQ EG G R + PG P Sbjct: 327 ATGAAGPPGPTGPAGPPGFPGAV-----GAKGEAGPQGPRGSEGPQGVRGE----PGPPG 377 Query: 606 HEDLNLIQQERPSSLPDLSGS--IDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFS 663 P+ +G+ D P A + ++ + S P Q P Sbjct: 378 -----------PAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGP-QGPGG 425 Query: 664 PHASPHLSSIPGGP----------SPSPVG-----SPVGSNQSRS--GPISPASIPGSQM 706 P S PG P P PVG P G R G P +PG Sbjct: 426 PPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPG--- 482 Query: 707 PPQPPGSQSESSSHPALSQSPMPQERGF-----MAGTQRNPQMAQYGPQQTGPSMSPHPS 761 PPG + P RGF +AG + P + P GP SP + Sbjct: 483 ---PPGERGG------------PGSRGFPGADGVAG-PKGPAGERGSPGPAGPKGSPGEA 526 Query: 762 PGGQMHAGISSFQ-QSNSSGTYGP--QMSQYGPQGNYSRPPAYSGVPSASYSG-----PG 813 G AG+ + + S G+ GP + GP G R P G P A PG Sbjct: 527 -GRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGR-PGPPGPPGARGQAGVMGFPG 584 Query: 814 PGMGISANNQMHGQGPSQPCGAV-PLGRMPSAGMQNRPFP----GNMSSMTPS-SPGMSQ 867 P + +G P GAV P G+ AG Q P P G P+ SPG Sbjct: 585 PKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGF-- 642 Query: 868 QGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNN 927 QG PG P + ++ + A S + FPG + G+ P + P Sbjct: 643 QGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPG--ERGVQGPPGP-AGPRGA 699 Query: 928 SSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGE---SKLPLPLKADGKEEGTPQPES 984 + + N A + AP S A GL M PGE + LP P K D + G + Sbjct: 700 NGAPGNDGAKGDAGAPGAPGSQGAP-GLQGM--PGERGAAGLPGP-KGDRGDAGPKGADG 755 Query: 985 KSKKSSSSTTTG 996 K TG Sbjct: 756 SPGKDGVRGLTG 767 Score = 49.3 bits (116), Expect = 4e-05 Identities = 137/571 (23%), Positives = 179/571 (31%), Gaps = 115/571 (20%) Query: 482 QQSSPYPGGSYGPPGP----------------QRYPIGIQGRTPGAMAGMQYPQQQDSGD 525 Q P P G GPPGP ++ GI PG M Sbjct: 137 QPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGIS--VPGPMGPSGPRGLPGPPG 194 Query: 526 ATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQD 585 A + F P + G+ G SG P+ P PP ++ + +P + Sbjct: 195 APGPQGFQGPPGEPGEPGASG----------PMGPRGPPGPPGKNGDDGEAGKPGRPGER 244 Query: 586 MSQEGYGTRSQPPLA--PGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSS--- 640 G R P A PG H S L G D P G + S Sbjct: 245 GPPGPQGARGLPGTAGLPGMKGHRGF--------SGLDGAKG--DAGPAGPKGEPGSPGE 294 Query: 641 --AVSASGSTSSQGDQSNP-AQSPFSPHASPHLSSIPGGPSPS-PVGSP-----VGSN-- 689 A G G++ P A P + + G P P+ P G P VG+ Sbjct: 295 NGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGE 354 Query: 690 ---QSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGF--MAGTQRNP-Q 743 Q G P + G PP P G+ + + A Q G +AG P Sbjct: 355 AGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGA 414 Query: 744 MAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQ--YGPQGNYSR---- 797 GPQ GP P P S + + G GP Q GP G + Sbjct: 415 RGPSGPQ--GPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGAR 472 Query: 798 -PPAYSGVPSASYSGPGPG-MGISANNQMHG-QGPSQPCGAV-PLGRMPSAGMQNRP--- 850 P +G+P GPG G + + G +GP+ G+ P G S G RP Sbjct: 473 GEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEA 532 Query: 851 -FPGNMS-SMTPSSPGMSQQGGP--------GMGPPMPTVNRKAQEAAAAVM------QA 894 PG + +P SPG + GP GPP P R A VM A Sbjct: 533 GLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGAR----GQAGVMGFPGPKGA 588 Query: 895 AANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVG 954 A ++ + PG P + Q PP PA G Sbjct: 589 AGEPGKAGERGVPG----------PPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAG 638 Query: 955 LADMMSPGESKLPLPLKADGK-----EEGTP 980 SPG LP P G+ E+G P Sbjct: 639 -----SPGFQGLPGPAGPPGEAGKPGEQGVP 664 Score = 47.0 bits (110), Expect = 2e-04 Identities = 60/203 (29%), Positives = 66/203 (32%), Gaps = 35/203 (17%) Query: 82 LGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGR 141 L G G + GP + G G A PPG + AP G P GR Sbjct: 975 LPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPG------ESGREGAPGAEGSP--GR 1026 Query: 142 YEHPGL----GALGTQQPPVA--VPGGGG--GPAAVPEFNNYYGSAAPASG-GPGGRAGP 192 PG G G PP A PG G GPA G A PA GP G GP Sbjct: 1027 DGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGP 1086 Query: 193 CFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGG 252 G Q P + G G H G+ Q G P G Sbjct: 1087 -----AGPQGPRGDKGETGEQGDRGIKG--------HRGFSGLQ-----GPPGPPGSPGE 1128 Query: 253 GGGGGGGGGSGGGGGGGGAGAGG 275 G G G +G G G AGA G Sbjct: 1129 QGPSGASGPAGPRGPPGSAGAPG 1151 Score = 37.7 bits (86), Expect = 0.12 Identities = 67/251 (26%), Positives = 80/251 (31%), Gaps = 50/251 (19%) Query: 674 PGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERG 733 P GP P G P R G +PG PP PPG P L + PQ Sbjct: 119 PRGPR-GPAGPP-----GRDGIPGQPGLPGPPGPPGPPGP-------PGLGGNFAPQ--- 162 Query: 734 FMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQ----QSNSSGTYGPQMSQY 789 G P GPS P PG G FQ + G GP M Sbjct: 163 LSYGYDEKSTGGISVPGPMGPS-GPRGLPGPPGAPGPQGFQGPPGEPGEPGASGP-MGPR 220 Query: 790 GPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPL-GRMPSAGMQ- 847 GP G PP +G + PG +GP P GA L G GM+ Sbjct: 221 GPPG----PPGKNGDDGEAGKPGRPG----------ERGPPGPQGARGLPGTAGLPGMKG 266 Query: 848 NRPFPGNMSSM----------TPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAAN 897 +R F G + P SPG + G PG P + + A A N Sbjct: 267 HRGFSGLDGAKGDAGPAGPKGEPGSPG--ENGAPGQMGPRGLPGERGRPGAPGPAGARGN 324 Query: 898 SAQSRQGSFPG 908 + PG Sbjct: 325 DGATGAAGPPG 335 Score = 35.4 bits (80), Expect = 0.62 Identities = 75/331 (22%), Positives = 97/331 (29%), Gaps = 36/331 (10%) Query: 1123 PSPANSGSLQGPQTPQ-STGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDP 1181 P P GP+ S G + + + G + PP PA P + G + Sbjct: 739 PGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGA 798 Query: 1182 FSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQG 1241 D + P P G + P P + G + G P G Sbjct: 799 PGDRGE----------PGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAG 848 Query: 1242 QMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYG 1301 P + ++ GA + G FP A R P G G P G P Sbjct: 849 --PPGPIGNVGAPGAKGARGSAGPPGATGFPGAAG---RVGPPGPS--GNAGPPGPPGPA 901 Query: 1302 GHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYG--------GSY 1353 G + G P+ G GPP + G G Sbjct: 902 GKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVV 961 Query: 1354 SGPDRRPIQG--QYPYPYSRERMQGPGQIQTHGIPPQMMG-----GPLQSSSSEG-PQQN 1405 P +R +G P P QGP PP MG GP S EG P Sbjct: 962 GLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAE 1021 Query: 1406 MWAARNDMPYPYQNR--QGPGGPTQAPPYPG 1434 R+ P +R GP GP AP PG Sbjct: 1022 GSPGRDGSPGAKGDRGETGPAGPPGAPGAPG 1052 Score = 35.0 bits (79), Expect = 0.81 Identities = 88/379 (23%), Positives = 121/379 (31%), Gaps = 68/379 (17%) Query: 1099 ERGEEPPPEVFSTGDTKKQPKLQ-PPSPANSGSLQGPQTPQST----------------G 1141 ERG PP + Q PP PA +G Q P + G Sbjct: 597 ERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAG 656 Query: 1142 SNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDP--FSDVSDSSFPKRNSMTPN 1199 VPGDL P P+ + P + G P + + K ++ P Sbjct: 657 KPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPG 716 Query: 1200 APYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYN----QS 1255 AP QG P + G MP E G + G + P G ++ + Sbjct: 717 APGSQG--APGLQG-MPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPG 773 Query: 1256 PSGAMSNLGMGQRQQFPYGAS--YDRRHEPYGQQYPGQGPPSG--QPPYGGHQPGLYPQQ 1311 P+GA + G + P G + R P + PG P+G PP QPG + Sbjct: 774 PAGAPGDKG----ESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEP 829 Query: 1312 PNYKRHMD-------GMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQ 1364 + D G GPP G + N+ + GS P G Sbjct: 830 GDAGAKGDAGPPGPAGPAGPP-----GPIGNVGAPGAKGAR-----GSAGPP------GA 873 Query: 1365 YPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARN-------DMPYPY 1417 +P + R+ PG G P GP +GP+ A P P Sbjct: 874 TGFPGAAGRVGPPGPSGNAG--PPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPA 931 Query: 1418 QNRQGPG--GPTQAPPYPG 1434 + PG GP AP PG Sbjct: 932 GEKGSPGADGPAGAPGTPG 950 Score = 33.5 bits (75), Expect = 2.4 Identities = 33/107 (30%), Positives = 42/107 (39%), Gaps = 11/107 (10%) Query: 70 QQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPP-LLSKPGDE- 127 +Q I + G G PG EQ G A G A P GPP PG + Sbjct: 1101 EQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSG------ASGPAGPRGPPGSAGAPGKDG 1154 Query: 128 -DDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFN 173 + P +G P G R G +G PP PG G P+A +F+ Sbjct: 1155 LNGLPGPIG-PPGPRGRTGDAGPVGPPGPP-GPPGPPGPPSAGFDFS 1199 >gi|48762934 alpha 2 type I collagen [Homo sapiens] Length = 1366 Score = 113 bits (282), Expect = 2e-24 Identities = 208/827 (25%), Positives = 269/827 (32%), Gaps = 128/827 (15%) Query: 77 SNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPP-LLSKPGDE-----DDA 130 S N G+ G PGP E+ + G + G A PPGPP L PG D Sbjct: 357 SGNKGEPGSAGPQGPPGPSGEEGKRG---PNGEAGSAGPPGPPGLRGSPGSRGLPGADGR 413 Query: 131 PPKMGEPA----------------GGRYEHPGL-GALGTQQPPVAV-PGGGGGPAAVPEF 172 MG P GR PGL G G P + P G GP +P Sbjct: 414 AGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGI 473 Query: 173 NNYYGSAAPAS--GGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHE 230 + G PA G PG P G H+ A A GAPG N + Sbjct: 474 DGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDG--NNGAQ 531 Query: 231 GYPNSQ----------------CNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAG 274 G P Q PG S P G G G G G G G G Sbjct: 532 GPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGER 591 Query: 275 GAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMG-PGGGGAASLS 333 G + AA + G G G G+ GV+ + G G PG GAA + Sbjct: 592 GPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIP 651 Query: 334 KAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPP-- 391 G + G N GA + +P P + + P+ P P Sbjct: 652 GGKGEKGEPGLRGEIG-NPGRDGARGAPG-AVGAPGPAGATGDRGEAGAAGPAGPAGPRG 709 Query: 392 ---------PSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPA 442 P+ P A AGAA GQ A G K + P + PA Sbjct: 710 SPGERGEVGPAGPNGFAGPAGAA--GQPGAKGERGAKGPKGENGVVGPTGPVG--AAGPA 765 Query: 443 MSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPI 502 G PGP R G P GM P + + P P G GPPGP Sbjct: 766 GPNGPPGPAGSRGDGGPP-----------GMTGFPGAAGRTGPPGPSGISGPPGPP---- 810 Query: 503 GIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQY-GQQGVSGYCQQGQQPYYSQQPQ 561 P G++ P+ E + PP + G++G SG P + PQ Sbjct: 811 -----GPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPP-GTPGPQ 864 Query: 562 PPHLPPQAQYLPSQSQQRYQP--QQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSS 619 P LP +R P + + G + PP A G P Sbjct: 865 GLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPG-----------AVG 913 Query: 620 LPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSP 679 P ++G+ EA G G + + + + P G P P Sbjct: 914 SPGVNGA------PGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGP--VGAAGAPGP 965 Query: 680 -SPVGSPVGSNQSR-----SGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERG 733 PVG P G + +R SGP+ PA G + P P G + + +P +G Sbjct: 966 HGPVG-PAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKG 1024 Query: 734 FMAGTQRNPQMA-----QYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQ 788 G Q P +A Q P GP+ P G AG ++ GT GP + Sbjct: 1025 H-NGLQGLPGIAGHHGDQGAPGSVGPA-GPRGPAGPSGPAGKDG--RTGHPGTVGPAGIR 1080 Query: 789 YGPQGNY--SRPPAYSGVPS-ASYSGPGPGMGISANNQMHGQGPSQP 832 GPQG+ + PP G P SG G G + Q S P Sbjct: 1081 -GPQGHQGPAGPPGPPGPPGPPGVSGGGYDFGYDGDFYRADQPRSAP 1126 Score = 99.8 bits (247), Expect = 3e-20 Identities = 208/905 (22%), Positives = 273/905 (30%), Gaps = 172/905 (19%) Query: 87 GGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPG 146 G A GP E+ G G PPGPP PG PP +G +Y+ G Sbjct: 33 GPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPP--GPPG-----PPGLGGNFAAQYDGKG 85 Query: 147 LGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA----PASGGPGGRAGPCFDQHGGQQS 202 +G LG + P G G A P + G A P GP G GP G Sbjct: 86 VG-LGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGP-----AGPPG 139 Query: 203 PGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGS 262 H G G + P G+P + PG+ G G G G Sbjct: 140 KAGEDGHPGKPGRPGERGVVGP--QGARGFPGTP--GLPGFKGIRGHNGLDGLKGQPGAP 195 Query: 263 GGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMM 322 G G G G G A G G G GS G + G Sbjct: 196 GVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSA--- 252 Query: 323 GPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEY 382 GP G A K G+ N P+G ++ P Sbjct: 253 GPPGFPGAPGPKGEIGAVG---------NAGPAGPAGPRGEV-------------GLPGL 290 Query: 383 SSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGM----------GLGKDMGAQYAAASPAW 432 S P PP P A A G A G+ G GA+ P Sbjct: 291 SGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGP 350 Query: 433 AAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPY-PGGS 491 A ++ S PG+ GP QG P P + + P GS Sbjct: 351 AGSKGESGNKGEPGSAGP-----QGPP----------------GPSGEEGKRGPNGEAGS 389 Query: 492 YGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQG 551 GPPGP G++G +PG+ +P G+ GV G Sbjct: 390 AGPPGPP----GLRG-SPGSRG---------------------LPGADGRAGVMG----- 418 Query: 552 QQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNL 611 PP ++ + R P D + G P PG P ++ Sbjct: 419 --------------PPGSRGASGPAGVR-GPNGDAGRPGEPGLMGPRGLPGSPG--NIGP 461 Query: 612 IQQERPSSLPDLSGSIDDL-PTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHL 670 +E P LP + G + P G + G +G +P ++ HA L Sbjct: 462 AGKEGPVGLPGIDGRPGPIGPAGARGEPGNI----GFPGPKGPTGDPGKNGDKGHAG--L 515 Query: 671 SSIPGGPSPSPVGSPVGSNQSRSGPISPASI---PGSQMPPQPPGSQSESSSHPALSQSP 727 + G P P N GP P + G Q PP PPG Q + Sbjct: 516 AGARGAPGPD-------GNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVG 568 Query: 728 MPQERGFMAGTQRNPQMAQYG-PQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQM 786 P ERG ++G P GP P PG AG + S G GP Sbjct: 569 KPGERGL---------HGEFGLPGPAGPRGERGP-PGESGAAGPTG--PIGSRGPSGPP- 615 Query: 787 SQYGPQGNYSRPPAYSGVPSASYSGPG--PGMGISANNQMHGQGPSQPCGAVPLGRMPSA 844 GP GN P V +A SGP PG A G+G G G + + Sbjct: 616 ---GPDGNKGEPGVVGAVGTAGPSGPSGLPGER-GAAGIPGGKGEKGEPGL--RGEIGNP 669 Query: 845 GMQN-RPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQ 903 G R PG + + P+ + GP P R + V A N Sbjct: 670 GRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPA 729 Query: 904 GSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVG-LADMMSPG 962 G+ G + P + ++ P + PA N G D PG Sbjct: 730 GAAGQPGAKGERGAKGP-----KGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPG 784 Query: 963 ESKLP 967 + P Sbjct: 785 MTGFP 789 Score = 53.9 bits (128), Expect = 2e-06 Identities = 82/294 (27%), Positives = 101/294 (34%), Gaps = 62/294 (21%) Query: 73 QHPISNNNSLGGAG--GGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDA 130 Q P+ +G G G A + GP S G A PPG P P A Sbjct: 825 QGPVGRTGEVGAVGPPGFAGEKGP------------SGEAGTAGPPGTP---GPQGLLGA 869 Query: 131 PPKMGEPAGGRYEH--PGLGALGTQQPPVAV---PGGGGGPAAV--PEFNNYYGSAA--- 180 P +G P G R E PG+ + P+ + PG G P AV P N G A Sbjct: 870 PGILGLP-GSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDG 928 Query: 181 -PASGGPGGRAGPCFDQHGGQQS-PGMGMMHSASAAAAGAPGSMDPLQ------NSHEGY 232 P + GP GR G H G++ PG + AAGAPG P+ N E Sbjct: 929 NPGNDGPPGRDGQ--PGHKGERGYPG----NIGPVGAAGAPGPHGPVGPAGKHGNRGETG 982 Query: 233 PNSQCNHY--------------------PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAG 272 P+ PG P G G G G G G G G Sbjct: 983 PSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQG 1042 Query: 273 AGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGG 326 A G+ A A + AG G G+ G+ G+ QG GP G Sbjct: 1043 APGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPG 1096 >gi|5453638 AT rich interactive domain 3B [Homo sapiens] Length = 560 Score = 106 bits (264), Expect = 3e-22 Identities = 93/333 (27%), Positives = 155/333 (46%), Gaps = 41/333 (12%) Query: 831 QPCGAVPLGRM----PSAGMQNRPFPGNMSSMTPSSPG-MSQQGGPGMGPPMPTVNRKAQ 885 +P G+ PLG + P+A + GNM+S G + + G + + Sbjct: 59 RPSGSTPLGPLARVPPTAAVAQVFERGNMNSEPEEEDGGLEDEDG----------DDEVA 108 Query: 886 EAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAM 945 E A QAA+ ++ +A P PM+N L PP+ Sbjct: 109 EVAEKETQAASKYFHVQK-----------VARQDPRVAPMSNL--LPAPGLPPHGQQAKE 155 Query: 946 VNSSAASVGLADMMSPGESKLPLP--LKADGKEEGTPQPESKSKKSSSSTTTGEKITKVY 1003 ++ AS + + G+ L LK +G + + + S K+Y Sbjct: 156 DHTKDASKASPSVSTAGQPNWNLDEQLKQNGGLAWSDDADGGRGREIS-----RDFAKLY 210 Query: 1004 ELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKK 1063 EL +PERK ++D FM++RG+P++ +P + K+ LDL+ LY V E GGL ++ K Sbjct: 211 ELDGDPERKEFLDDLFVFMQKRGTPINRIPIMAKQILDLYMLYKLVTEKGGLVEIINKKI 270 Query: 1064 WRELATNLNVGTS-SSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQP 1122 WRE+ LN+ TS +SAA +L+ QY++YL+A+EC+ ++ P E+ + D ++ + Sbjct: 271 WREITKGLNLPTSITSAAFTLRTQYMKYLYAYECE-KKALSSPAELQAAIDGNRR---EG 326 Query: 1123 PSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPP 1155 P+ S SL G +P + + + A P L PP Sbjct: 327 RRPSYSSSLFG-YSPAAATAAAAAGAPALLSPP 358 >gi|4885193 AT rich interactive domain 3A (BRIGHT- like) protein [Homo sapiens] Length = 593 Score = 104 bits (260), Expect = 8e-22 Identities = 68/197 (34%), Positives = 107/197 (54%), Gaps = 14/197 (7%) Query: 954 GLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKL 1013 G+ ++ E P P G PQ + T E+ ++YEL +P+RK Sbjct: 187 GVPRVLGGQERPGPGPAHPGGAAHVAPQLQPPDH---GDWTYEEQFKQLYELDGDPKRKE 243 Query: 1014 WVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNV 1073 ++D +FM++RG+PV+ +P + K+ LDLF LYV V E GGL +V K WRE+ LN+ Sbjct: 244 FLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNL 303 Query: 1074 GTS-SSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQP--------KLQPPS 1124 TS +SAA +L+ QY++YL+ +EC+ +RG P E+ + D+ ++ L S Sbjct: 304 PTSITSAAFTLRTQYMKYLYPYECE-KRGLSNPNELQAAIDSNRREGRRQSFGGSLFAYS 362 Query: 1125 PANS-GSLQGPQTPQST 1140 P + G L P+ P S+ Sbjct: 363 PGGAHGMLSSPKLPVSS 379 Score = 40.0 bits (92), Expect = 0.025 Identities = 18/51 (35%), Positives = 23/51 (45%) Query: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAA 291 P P + GGGGGGG S GG GG G G AG + + + + Sbjct: 538 PPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTS 588 Score = 37.0 bits (84), Expect = 0.21 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 8/93 (8%) Query: 1646 GDPSQKALDHNAARKDDSQSLADDSG-----KEEEDAECIDDDEEDEEDEEEDSEKTESD 1700 G P ++ + +A D +EEE E + +DEE+EE++ ED E+ E + Sbjct: 97 GTPGSPGRGREGPGEEHFEDMASDEDMKPKWEEEEMEEDLGEDEEEEEEDYEDEEEEEDE 156 Query: 1701 E---KSSIALTAPDAAADPKEKPKQASKFDKLP 1730 E A A K +P QA + D +P Sbjct: 157 EGLGPPGPASLGTTALFPRKAQPPQAFRGDGVP 189 Score = 33.9 bits (76), Expect = 1.8 Identities = 27/98 (27%), Positives = 42/98 (42%), Gaps = 1/98 (1%) Query: 59 QQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSA-AGGQADPPG 117 Q+QQ+ +Q+ + +QQ P + G AP + E + A+ +A A +A G Sbjct: 12 QRQQRARQELEARQQLPPDPPAAPPGRARAAPDEDREPESARMQRAQMAALAAMRAAAAG 71 Query: 118 PPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQP 155 + PG +D PP E R PG G + P Sbjct: 72 LGHPASPGGSEDGPPGSEEEDAAREGTPGSPGRGREGP 109 >gi|57864582 hornerin [Homo sapiens] Length = 2850 Score = 102 bits (255), Expect = 3e-21 Identities = 222/974 (22%), Positives = 327/974 (33%), Gaps = 121/974 (12%) Query: 73 QHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPP 132 QH S+ S G + G+ G QHG ++ G+ + + Sbjct: 233 QHKSSSGQSSGYSQHGSGS-GHSSGYGQHGSRSGQSSRGE----------RHRSSSGSSS 281 Query: 133 KMGEPAGGRYEHPGLG--ALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGG---PG 187 G+ G + G G G++Q P V G G + + GS+ S G G Sbjct: 282 SYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESG 341 Query: 188 GRAGPCFDQH-------GGQQSPGMGMMHSAS----------AAAAGAPGSMDPLQNSHE 230 F QH G G G HS+S A+++G GS Q+S Sbjct: 342 SGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSR-QSSSY 400 Query: 231 GYPNSQCNHYPGYSRPGAGGGGGGGGGG-GGGSGGGGGGGGAGAGGAGAGAVAAAAAAAA 289 G S H G + +G G G G G GSG G G G ++++ Sbjct: 401 GQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTG------FGRSSSSGP 454 Query: 290 AAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAA-----GSAAGGF 344 +G G G+G + S Q G G G G S S ++ GS+AG Sbjct: 455 YVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSS 514 Query: 345 QRFAGQNQHPSGATPTLNQLL------TSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQ 398 + QH SG+ +L SPSP G + S S+ P + Sbjct: 515 SSY---GQHGSGSRQSLGHSRHGSGSGQSPSPSR----GRHESGSRQSSSYGPHGYGSGR 567 Query: 399 AAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGS 458 +++ G G ++G+G + Q S + S + + G G T G+S Sbjct: 568 SSSRGPYESGSGHSSGLGHQESRSGQ----SSGYGQHGSSSGHSSTHGQHGSTSGQSSSC 623 Query: 459 PMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYP 518 + +G + SQ + GS P R+ G+ G Sbjct: 624 GQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRH---------GSDFGHSSS 674 Query: 519 QQQDSGDATWKETFWLMPPQYGQQGVSGY-CQQGQQPYYSQQPQPPHLPPQAQYLPSQSQ 577 Q + W + GQ G+ GQ YSQ + S+S Sbjct: 675 YGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSG 734 Query: 578 QRYQPQQDMSQEG-------YGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDL 630 Q + +Q S G +G+ S G+ + + R S S S Sbjct: 735 QSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQH 794 Query: 631 PTGTEATLSSA--VSASGSTSSQGDQSNPAQSPFSPH--ASPHLSSIPGGPSPSPVGSPV 686 +GT + S S SG S G + + +S H AS H SS S S S Sbjct: 795 GSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSS 854 Query: 687 GSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPA---------LSQSPMPQERGFMAG 737 G + S SG S Q ES+SH A QSP +RG +G Sbjct: 855 GQHDSSSGQSSSY-------------GQHESASHHASGRGRHGSGSGQSPGHGQRG--SG 899 Query: 738 TQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSR 797 + ++P ++G S S G +G S S Y S G +Y + Sbjct: 900 SGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQ 959 Query: 798 PPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSS 857 + SG S S G G S++ HG G Q G G +G P P Sbjct: 960 HGSRSGQSSRS-EQHGSSSGSSSSYGQHGSGSRQSLGHGQHG----SGSGQSPSPSR--G 1012 Query: 858 MTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMAS 917 S G S GP + +R E+ + + +SR G G Q G +S Sbjct: 1013 RHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSG-HSSGLGHRESRSGQSSGYGQHG--SS 1069 Query: 918 SSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEE 977 S S + S+ + + A + +SS G S G + G+ Sbjct: 1070 SGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG---SGSGQSP 1126 Query: 978 GTPQPESKSKKSSS 991 G Q S S++S S Sbjct: 1127 GHGQRGSGSRQSPS 1140 Score = 102 bits (254), Expect = 4e-21 Identities = 303/1398 (21%), Positives = 477/1398 (34%), Gaps = 185/1398 (13%) Query: 74 HPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPK 133 H S+ +S G G+ G QHG ++ G+ + G + Sbjct: 468 HESSSEHSSGYTQHGSGS-GHSSGHGQHGSRSGQSSRGE----------RQGSSAGSSSS 516 Query: 134 MGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNY----YGSAAPASGGP--- 186 G+ G + G G+ P G + + ++Y YGS +S GP Sbjct: 517 YGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYES 576 Query: 187 --GGRAGPCFDQHGGQQSPGMGMMHSAS---------------AAAAGAPGSMDPLQNSH 229 G +G + QS G G S+S +++ G G+ +SH Sbjct: 577 GSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSH 636 Query: 230 EGYPNSQCNHYPGYSRPGAGGG-----GGGGGGGGGGSGGGGGGGGAGAGGAGA--GAVA 282 G S + Y + G+G G G G G S G G G+G + G+V+ Sbjct: 637 -GQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVS 695 Query: 283 AAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQG--GGMMMGPGGGGAASLSKAAAGSA 340 ++ +G G GY +G S R+ G G G++S ++ G Sbjct: 696 GQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQH 755 Query: 341 AGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAA 400 G + +G + SG+ + +++ S S G + +S S S + Sbjct: 756 GSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCS------SSCGHYES 809 Query: 401 AAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPM 460 +G A+G Q +G G G +Q+ +AS ++ S G G T G+S S Sbjct: 810 GSGQASGFGQHESGSGQGY---SQHGSASGHFS----------SQGRHGSTSGQSSSSGQ 856 Query: 461 DPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTP-----GAMAGM 515 + YG + + GS PG + G G++P G+ +G Sbjct: 857 HDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSG-SGQSPSYGRHGSGSGR 915 Query: 516 QYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQ 575 + G + + + + GQ SGY Q G +S + H Q S+ Sbjct: 916 SSSSGR-HGSGSGQSSGFGHKSSSGQS--SGYTQHGSGSGHSSSYE-QHGSRSGQ--SSR 969 Query: 576 SQQRYQPQQDMSQEG-YGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGT 634 S+Q S G +G+ S+ L G+ Q PS SGS G Sbjct: 970 SEQHGSSSGSSSSYGQHGSGSRQSLGHGQ---HGSGSGQSPSPSRGRHGSGS------GQ 1020 Query: 635 EATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSG 694 ++ S SG +SS+G P +S S H S + S S S G + S SG Sbjct: 1021 SSSYGPYRSGSGWSSSRG----PYES-----GSGHSSGLGHRESRSGQSSGYGQHGSSSG 1071 Query: 695 PISPASIPGSQMPP-----QPPGSQSESSSH----PALSQSPMPQERGFMAGTQRNPQMA 745 S GS Q S +SSSH SQS +G +G+ ++P Sbjct: 1072 HSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG--SGSGQSPGHG 1129 Query: 746 QYGP-QQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGV 804 Q G + PS H S G+ + S +G S G +YS+ + SG Sbjct: 1130 QRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSG- 1188 Query: 805 PSASYSGPGPGMGISANNQMHG--QGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSS 862 S+ Y G G S+ + HG G S G G S+G G S + S Sbjct: 1189 HSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSG------HGRQGSGSGHS 1242 Query: 863 PGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQG--SFPGMNQSGLMASSSP 920 P + G G+G + Q + + ++ +SR G S G ++SG SS Sbjct: 1243 PSRGRHGS-GLGHS----SSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESG-SGHSSA 1296 Query: 921 YSQPMNNSSSLMNT-QAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGT 979 YSQ + S + Q S + + +S G + S G+ Sbjct: 1297 YSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGS 1356 Query: 980 PQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKP 1039 Q S+ + S S + G W + GS G Sbjct: 1357 GQSPSRGRHGSGSGHSS-------SYGQHGSGSGW----SSSSGRHGSGSGQSSGFGHHE 1405 Query: 1040 LDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIE 1099 ++ C + G + ++ + + G ++S Y Q+ + Sbjct: 1406 SSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLG 1465 Query: 1100 R-------GEEPPPEVFSTGDTKKQPKLQPPSPANSG--SLQGPQTPQSTGSNSMAEVPG 1150 G+ P P G Q P + SG S +GP S+ S+ + G Sbjct: 1466 HGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGL----G 1521 Query: 1151 DLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQ---GMS 1207 + + S+ +GQ G SST H S S S S ++ + Q G S Sbjct: 1522 HRESRSGQSSGYGQ-HGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSS 1580 Query: 1208 MPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQ 1267 GR + P G R P + G+ + S +S S G+G+ Sbjct: 1581 QSSGYGRQGSGSGQSPGHGQRGSGSRQSP--SYGRHGSGS-----GRSSSSGQHGSGLGE 1633 Query: 1268 RQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAK 1327 F + S + Y Q G G SG +G Q +RH + Sbjct: 1634 SSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS----GQSSRGERH-------GSS 1682 Query: 1328 RHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPP 1387 Y S +Q + +G SG + P +G++ G G +HG Sbjct: 1683 SRSSSRYGQHGSGSRQS--SGHGRQGSGSGQSPSRGRHG--------SGLGHSSSHG--- 1729 Query: 1388 QMMGGPLQSSSSEGPQQN 1405 G SSS GP ++ Sbjct: 1730 -QHGSGSGRSSSRGPYES 1746 Score = 94.7 bits (234), Expect = 9e-19 Identities = 184/815 (22%), Positives = 283/815 (34%), Gaps = 99/815 (12%) Query: 163 GGGPAAVPEFNNYYGSAAPASG----GPGGRAGPCFDQHGGQQSPGM-GMMHSASAAAAG 217 G G F ++ S+ +SG G G ++QHG + G H +S+ ++ Sbjct: 1392 GSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSS 1451 Query: 218 APGSMDPLQNSHEGYPNSQCNHYPGYS-RPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGA 276 + G S + + Q G S P G G G G S G G G + + G Sbjct: 1452 SYGQHG--SGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGP 1509 Query: 277 GAGAVAAAAAAAAAAAGGGGGGGYG--GSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSK 334 + ++ + G GYG GSS+G+ G G GA+S Sbjct: 1510 YESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQS 1569 Query: 335 AAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQ 394 ++ G G + +G + SG+ SP R G PS Sbjct: 1570 SSHGQHGSGSSQSSGYGRQGSGSG-------QSPGHGQRGSGSR-----------QSPSY 1611 Query: 395 PQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQR----SHPAMSPGTPGP 450 + + + +++ GQ G GLG+ G + +S +++ + S + G G Sbjct: 1612 GRHGSGSGRSSSSGQH---GSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGS 1668 Query: 451 TMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGI------ 504 G+S + YG + Q GS P R+ G+ Sbjct: 1669 RSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSH 1728 Query: 505 -QGRTPGAMAGMQYPQQQDSGDAT---WKETFWLMPPQYGQQGVSG--YCQQGQQPYYSQ 558 Q + + + P + SG ++ E+ Y Q G +C QGQ S Sbjct: 1729 GQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSG 1788 Query: 559 QPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPS 618 Q + Q+ Q S +G+ S + G+ + R Sbjct: 1789 QSS------------TFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHG 1836 Query: 619 SLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQG----DQSNPAQSPFSPH--ASPHLSS 672 S S S +G+ + SS SGS S G + S+ S ++ H S H SS Sbjct: 1837 SGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSS 1896 Query: 673 IPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQER 732 S S S + S SG S GS Q S S QSP P Sbjct: 1897 YEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS----GQSPSPSRG 1952 Query: 733 GFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNS--SGTYGPQMSQYG 790 +G+ ++ YG +G S S P G H+ ++S S S YG S G Sbjct: 1953 RHGSGSGQSSSYGPYG-SGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSG 2011 Query: 791 PQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRP 850 + + + SG S+S G G S+++ HG G SQ G GR S Q+ P Sbjct: 2012 HSSTHGQHGSASG-QSSSCGQHGASSGQSSSHGQHGSGSSQSSG---YGRQGSGSGQS-P 2066 Query: 851 FPGNMSSMTPSSPGMSQQG------------GPGMGPPMPTVNRKAQEA-AAAVMQAAAN 897 G S + SP + G GPG+G + ++ +++ Q + Sbjct: 2067 GHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSG 2126 Query: 898 SAQS----RQGSFPGMNQSG-----LMASSSPYSQ 923 S S + GS G + G SSS Y Q Sbjct: 2127 SGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQ 2161 Score = 94.0 bits (232), Expect = 1e-18 Identities = 320/1466 (21%), Positives = 455/1466 (31%), Gaps = 162/1466 (11%) Query: 44 HHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGG 103 HH + Q + + Q Q S +S G G + Q G Sbjct: 1169 HHESSSGQSSSYSQHGSGSGHSSGYGQHGSR--SGQSSRGERHGSSSGSSSHYGQHGSGS 1226 Query: 104 AKDSAAGGQADPPG-PPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPG- 161 + S G Q G P + G G+ G G ++ +V G Sbjct: 1227 RQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQ 1286 Query: 162 ---GGGGPAAVPEFNNYYGSAAPASGGPGGRAGPC--FDQHG---GQQSP----GMGMMH 209 G G +A + + G + G G +G FDQ G GQ S G G Sbjct: 1287 HESGSGHSSAYSQHGSGSGHFC-SQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQ 1345 Query: 210 SASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGG-GGGSGGGGGG 268 S+ GA P + H S H Y + G+G G G G GSG G Sbjct: 1346 SSGYGRHGAGSGQSPSRGRH----GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGF 1401 Query: 269 G----------GAGAGGAGAGAVAAA---AAAAAAAAGGGGGGGYGGSSAGYGVLSS-PR 314 G G G+G+G ++ + + ++ G G GSS+ YG S R Sbjct: 1402 GHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSR 1461 Query: 315 QQGGGMMMGPGGGGAASLSKAAAGSAAG------------GFQRFAGQNQHPSGATPTLN 362 Q G G G G + S S+ GS +G G+ G + S + L Sbjct: 1462 QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLG 1521 Query: 363 QLLTSPSPMMRSYG--GSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD 420 S S YG GS +SS S S GA++G + G G Sbjct: 1522 HR-ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSS 1580 Query: 421 MGAQY------AAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMG 474 + Y + SP S + S G G GRS S + +G Sbjct: 1581 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHH 1640 Query: 475 SNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWL 534 + Q S + GS G ++ G+ +G Q + + G ++ + Sbjct: 1641 ESSSGQSSSYSQHGSGSGHSSGYGQH---------GSRSG-QSSRGERHGSSSRSSS--- 1687 Query: 535 MPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTR 594 +YGQ G G S Q P L S Q G G+ Sbjct: 1688 ---RYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSH--------GQHGSGSG 1736 Query: 595 SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQ 654 P + ++ Q S + S +G + S SG SS DQ Sbjct: 1737 RSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQ-SSTFDQ 1795 Query: 655 SNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQ 714 + S H H S S GS G + SR S G GS Sbjct: 1796 EGSSTGQSSSHGQ-HGSGSSQSSSYGQQGSGSGQSPSRG---RHGSGSGHSSSYGQHGSG 1851 Query: 715 SESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGP----SMSPHPSPGGQMHAGI 770 S SS S Q GF + Q + Y +G S H S GQ G Sbjct: 1852 SGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGE 1911 Query: 771 SSFQQSNSSGTYGPQMS---QYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQ 827 S SS +YG S Q G + S PS G G G S G Sbjct: 1912 QHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGS 1971 Query: 828 GPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEA 887 G S G G S+G+ G+ S + S G Q G + A Sbjct: 1972 GWSSSRGPYESGSGHSSGL------GHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQ 2025 Query: 888 AAAVMQAAANSAQS-----------------RQGS----FPGMNQSGLMASSSPYSQPMN 926 +++ Q A+S QS RQGS PG Q G + SP S + Sbjct: 2026 SSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSP-SYGRH 2084 Query: 927 NSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKS 986 S S ++ + + P + SS G + S S G G Q S+S Sbjct: 2085 GSGSGRSSSSGQHG--PGLGESSG--FGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS 2140 Query: 987 KKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLY 1046 +SS G G R + +GS P+ G+ Sbjct: 2141 GQSSRGERHGSSSGSSSRYGQHGSGS----RQSSGHGRQGSGSGHSPSRGRHGSGSGHSS 2196 Query: 1047 VCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPP 1106 + G + + + + + +V + S Y Q+ +G+ Sbjct: 2197 SHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQH--- 2253 Query: 1107 EVFSTGDTKKQPKL--QPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQ 1164 G T Q Q S S G S+ S+S + G +P+ HG Sbjct: 2254 -----GSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQ-QGSGSGQSPSRGRHGS 2307 Query: 1165 MTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPF 1224 + G SS+ H S S SS + ++ + S + Sbjct: 2308 GS----GHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGH 2363 Query: 1225 GGMRKVPGSSEPFMTQGQMPNSSM--QDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHE 1282 + GS ++G+ SS Y Q SG+ +LG GQ +G+ + Sbjct: 2364 SSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQ-----HGSGSGQSPS 2418 Query: 1283 P-YGQQYPGQGPPSGQPPYGGHQPGLYPQQP--NYKRHMDGMYGPPAKRHEGDMYNMQYS 1339 P G+ G G S PYG + P + H G+ ++ + Y S Sbjct: 2419 PSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGS 2478 Query: 1340 SQQQEMYNQYGGSYSGPDRRPIQ-GQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSS 1398 S + GS SG Q G S G G Q+ G Q G S Sbjct: 2479 SSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG----SGQ 2534 Query: 1399 SEGPQQNMWAARNDMPYPYQNRQGPG 1424 S G Q +R P R G G Sbjct: 2535 SPGHGQRGSGSRQS---PSYGRHGSG 2557 Score = 93.6 bits (231), Expect = 2e-18 Identities = 312/1474 (21%), Positives = 460/1474 (31%), Gaps = 164/1474 (11%) Query: 67 QQQQQQQHPISN--NNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKP 124 Q + +QH S+ ++S G G G+ Q Q G S + + Sbjct: 735 QSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQH 794 Query: 125 GDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASG 184 G G G + G G + G G G + + ++ S Sbjct: 795 GSGTSCSSSCGHYESGSGQASGFGQHES--------GSGQGYSQHGSASGHFSSQGRHGS 846 Query: 185 GPGGRAGPCFDQHGGQQSPGMGMMHSAS--AAAAGAPGSMDPLQNSHEGYPNSQCNHYPG 242 G + QS G SAS A+ G GS H G S P Sbjct: 847 TSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGH-GQRGSGSGQSPS 905 Query: 243 YSRPGAGGGGGGGGGG-GGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAA----GGGGG 297 Y R G+G G G G GSG G G + G +G + + +++ G G Sbjct: 906 YGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSG 965 Query: 298 --------GGYGGSSAGYGVLSS-PRQQGGGMMMGPGGGGAASLSKAAAGSAAG------ 342 G GSS+ YG S RQ G G G G + S S+ GS +G Sbjct: 966 QSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYG 1025 Query: 343 ------GFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYG--GSYPEYSSPSAPPPPPSQ 394 G+ G + SG + L S S YG GS +SS S Sbjct: 1026 PYRSGSGWSSSRGPYESGSGHSSGLGHR-ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSG 1084 Query: 395 PQSQAAAAGAAAGGQQAAAGMGLGKDMGAQY------AAASPAWAAAQQRSHPAMSPGTP 448 S GA++G + G G + Y + SP S + S G Sbjct: 1085 QSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 1144 Query: 449 GPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRT 508 G GRS S + +G + Q S + GS G ++ Sbjct: 1145 GSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQH-------- 1196 Query: 509 PGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGV-----SGYCQQGQQPYYSQQPQPP 563 G+ +G Q + + G ++ + YGQ G SG+ +QG +S P Sbjct: 1197 -GSRSG-QSSRGERHGSSSGSSS------HYGQHGSGSRQSSGHGRQGSGSGHS--PSRG 1246 Query: 564 HLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGK----PNHEDL---------N 610 + S Q + S+ Y +RS G+ H + Sbjct: 1247 RHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGH 1306 Query: 611 LIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHL 670 Q + S S + D + T + S SGS+ S G + A S SP H Sbjct: 1307 FCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHG 1366 Query: 671 SSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQ 730 S S S G + S SG S + GS ESSS QS Sbjct: 1367 SG-------SGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSW----QSSGCT 1415 Query: 731 ERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYG 790 + G +G+ + Q+G + S G+ H SS S+S G +G Q Sbjct: 1416 QHG--SGSGHSSSYEQHGSRSGQSSR-------GERHG--SSSGSSSSYGQHGSGSRQSL 1464 Query: 791 PQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRP 850 G + S PS G G G S + G G S G G S+G+ Sbjct: 1465 GHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGL---- 1520 Query: 851 FPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMN 910 G+ S + S G Q G + +++ Q A+S QS G Sbjct: 1521 --GHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSG 1578 Query: 911 QS-----GLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAAS------------V 953 S G S S S P + + Q+P Y + S++S Sbjct: 1579 SSQSSGYGRQGSGSGQS-PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGF 1637 Query: 954 GLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKL 1013 G + S S G G Q S+S +SS G G Sbjct: 1638 GHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGS- 1696 Query: 1014 WVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNV 1073 R + +GS P+ G+ L + G + + + + + +V Sbjct: 1697 ---RQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSV 1753 Query: 1074 GTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKL--QPPSPANSGSL 1131 + S Y Q+ +G+ G T Q Q S S Sbjct: 1754 FGQHESGSGHSSAYSQHGSGSGHFCSQGQH--------GSTSGQSSTFDQEGSSTGQSSS 1805 Query: 1132 QGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFP 1191 G S+ S+S + G +P+ HG + G SS+ H S S SS Sbjct: 1806 HGQHGSGSSQSSSYGQ-QGSGSGQSPSRGRHGSGS----GHSSSYGQHGSGSGWSSSSGR 1860 Query: 1192 KRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSM--Q 1249 + ++ + S + + GS ++G+ SS Sbjct: 1861 HGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSS 1920 Query: 1250 DMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEP-YGQQYPGQGPPSGQPPYGGHQPGLY 1308 Y Q SG+ +LG GQ +G+ + P G+ G G S PYG Sbjct: 1921 SSYGQHGSGSRQSLGHGQ-----HGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSS 1975 Query: 1309 PQQP--NYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQ-GQY 1365 + P + H G+ ++ + Y SS + GS SG Q G Sbjct: 1976 SRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGAS 2035 Query: 1366 PYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGG 1425 S G G Q+ G Q G S S G Q +R Y Sbjct: 2036 SGQSSSHGQHGSGSSQSSGYGRQGSG----SGQSPGHGQRGSGSRQSPSYGRHGSGSGRS 2091 Query: 1426 PTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVS 1459 + PG+ + + S + H S Sbjct: 2092 SSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGS 2125 Score = 86.7 bits (213), Expect = 2e-16 Identities = 234/999 (23%), Positives = 337/999 (33%), Gaps = 137/999 (13%) Query: 15 GEAPAAPPHQQHHHHHHAHHHHH----HAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQ 70 G + H+ H A+ H H H + Q + F Q+ Q Q Sbjct: 1749 GHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQ 1808 Query: 71 QQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS-KPGDEDD 129 S ++S G G G+ Q P + G S+ G G S + G Sbjct: 1809 HGSGS-SQSSSYGQQGSGSGQ-SPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSG 1866 Query: 130 APPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASG----- 184 G ++ G G+ + G + +GS++ +S Sbjct: 1867 QSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQH 1926 Query: 185 GPGGRAGPCFDQHG---GQQ-SPGMGMMHSASAAAA--GAPGSMDPLQNSHEGYPNSQCN 238 G G R QHG GQ SP G S S ++ G GS +S Y S Sbjct: 1927 GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPY-ESGSG 1985 Query: 239 HYPGY----SRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGG 294 H G SR G G G G G S G G A + G A++ +++ Sbjct: 1986 HSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQH 2045 Query: 295 GGGG----GYGGSSAGYGVLSSPRQQGGGMMMGPGGG--GAASLSKAAAGSAAGGFQRFA 348 G G GYG +G G Q+G G P G G+ S +++G G + Sbjct: 2046 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESS 2105 Query: 349 GQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGG 408 G H S + + + S + Y ++ S S S+ + +++G+++ Sbjct: 2106 GFGHHESSSGQSSSY---SQHGSGSGHSSGYGQHGSRSGQS---SRGERHGSSSGSSSRY 2159 Query: 409 QQAAAGMGLGKDMGAQYAAA--SPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMK 466 Q +G G Q + + SP+ S + S G G GRS Sbjct: 2160 GQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSG 2219 Query: 467 RPQLYGM---GSNPHSQPQQSSPYPG-----GSYGPPGPQRYPIGIQGRTPGAMAGMQYP 518 ++G GS S Q G G +G Q +G + G + Sbjct: 2220 HSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHG-- 2277 Query: 519 QQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQ 578 Q SG + YGQQG SG GQ P S+ + Y S Sbjct: 2278 -QHGSGSS--------QSSSYGQQG-SG---SGQSP--SRGRHGSGSGHSSSYGQHGSGS 2322 Query: 579 RYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATL 638 + G G S G +HE SS SG G+ + Sbjct: 2323 GWSSSSGRHGSGSGQSS------GFGHHE----------SSSWQSSGYTQH---GSGSGH 2363 Query: 639 SSAVSASGSTSSQGDQ------SNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSR 692 SS+ GS S Q + S+ + S + H S S+ G S G ++ R Sbjct: 2364 SSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGR 2423 Query: 693 SGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQT 752 G S G P GS S SS +S G R+ Q + YG Q Sbjct: 2424 HGSGS-----GQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYG--QH 2476 Query: 753 GPSMSPHPSPGGQMHAGISSFQQSNSSGTYGP---QMSQYGPQGN-------YSRPPAYS 802 G S S H S GQ H S QS+S G +G Q S +G G+ Y R + S Sbjct: 2477 GSS-SGHSSTHGQ-HGSTSG--QSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGS 2532 Query: 803 GV------------PSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRP 850 G S SY G G G S+++ HG G + G G S+ Q+ Sbjct: 2533 GQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSG---FGHHESSSGQSSS 2589 Query: 851 FPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQS----RQGSF 906 + + S SS G Q G + + +++ Q + S QS RQGS Sbjct: 2590 YSQHGSGSGHSS-GYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSG 2648 Query: 907 PGMNQ------SGLMASSSPYSQPMNNSSSLMNTQAPPY 939 G + SGL SS S + S S ++ PY Sbjct: 2649 SGQSPSRGRHGSGLGHSS---SHGQHGSGSGRSSSRGPY 2684 Score = 84.3 bits (207), Expect = 1e-15 Identities = 216/1029 (20%), Positives = 328/1029 (31%), Gaps = 149/1029 (14%) Query: 38 HAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDME 97 H+ L H + Q + + Q Q S + G G Sbjct: 1516 HSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHG----STSGQSSSCGQHGASSGQSSS 1571 Query: 98 QPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPV 157 QHG ++G + G P G+ G + P G G+ Sbjct: 1572 HGQHGSGSSQSSG----------YGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRS 1621 Query: 158 AVPGG-GGGPAAVPEFNNYYGSAAPASG----GPGGRAGPCFDQHG---GQQSPGMGMMH 209 + G G G F ++ S+ +S G G + QHG GQ S G Sbjct: 1622 SSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGS 1681 Query: 210 SASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGG 269 S+ +++ Q+S G S P R G+G G G G G Sbjct: 1682 SSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSR 1741 Query: 270 GAGAGGAGAGAV-----AAAAAAAAAAAGGGGGG-----GYGGSSAGYGVLSSPRQQGGG 319 G +G +V + + ++A + G G G G GS++G G Sbjct: 1742 GPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTG 1801 Query: 320 MMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSY 379 G G+ S ++ G G + + +H SG+ + SY Sbjct: 1802 QSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGS----------------GHSSSY 1845 Query: 380 PEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAA----ASPAWAAA 435 ++ S S ++++G G ++G G + Q + S + ++ Sbjct: 1846 GQHGSGSG----------WSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSS 1895 Query: 436 QQRSHPAMS-PGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPG-GSYG 493 H + S + G G S GS +G H SP P G +G Sbjct: 1896 SYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 1955 Query: 494 PPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATW---KETFWLMPPQYGQQGVSGYCQQ 550 Q G G G + + P + SG ++ +E+ YGQ G S Sbjct: 1956 SGSGQSSSYGPYGSGSG-WSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS 2014 Query: 551 GQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLN 610 + S Q S GYG + + P H Sbjct: 2015 THGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG--SGQSPGHGQRG 2072 Query: 611 LIQQERPSSLPDLSGS--------------------IDDLPTGTEATLSSAVSASGSTSS 650 ++ PS SGS + +G ++ S S SG +S Sbjct: 2073 SGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG 2132 Query: 651 QGDQSNPA--QSPFSPHASPHLSSIPGGP--SPSPVGSPVGSNQSRSGPISPASIPGSQM 706 G + + S H S SS G S S S G S SG GS Sbjct: 2133 YGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGS 2192 Query: 707 PPQPPGSQSESSSHPALSQSPMPQERGFMA-------GTQRNPQMAQYGPQQTG-PSMSP 758 Q S S + S+ P G + G+ + +Q+G S Sbjct: 2193 GHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQ 2252 Query: 759 HPSPGGQMHAGISSFQQSNSS----------GTYGPQMSQYGPQGNYS-------RPPAY 801 H S GQ S+F Q SS G+ Q S YG QG+ S R + Sbjct: 2253 HGSTSGQS----STFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSG 2308 Query: 802 SGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPS 861 SG S+SY G G G S+++ HG G Q G G S+ Q+ + + S S Sbjct: 2309 SG-HSSSYGQHGSGSGWSSSSGRHGSGSGQSSG---FGHHESSSWQSSGYTQHGSGSGHS 2364 Query: 862 SPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPY 921 S +Q G G + + ++ + + + SRQ G + SG S SP Sbjct: 2365 S--SYEQHGSRSG--QSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP- 2419 Query: 922 SQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQ 981 S+ + S S ++ PY + G + P ES G G Sbjct: 2420 SRGRHGSGSGQSSSYSPY----------GSGSGWSSSRGPYES-------GSGHSSGLGH 2462 Query: 982 PESKSKKSS 990 ES+S +SS Sbjct: 2463 RESRSGQSS 2471 Score = 80.5 bits (197), Expect = 2e-14 Identities = 178/841 (21%), Positives = 263/841 (31%), Gaps = 115/841 (13%) Query: 74 HPISNNNSLGGAGGGAPQPGPDMEQPQHGGA--------KDSAAGGQADPPGPPLLSKPG 125 H S + G G G QHG A + A+ GQ+ G + G Sbjct: 1992 HRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHG-----QHG 2046 Query: 126 DEDDAPPKMGEPAGGRYEHPGLGALGT---QQPPVAVPGGGGGPAAVPE----------- 171 G G + PG G G+ Q P G G G ++ Sbjct: 2047 SGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSG 2106 Query: 172 FNNYYGSAAPASG----GPGGRAGPCFDQHG---GQQSPGMGMMHSASAAAAGAPGSMDP 224 F ++ S+ +S G G + QHG GQ S G S+ +++ Sbjct: 2107 FGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGS 2166 Query: 225 LQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAV--- 281 Q+S G S H P R G+G G G G G G +G +V Sbjct: 2167 RQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQ 2226 Query: 282 --AAAAAAAAAAAGGGGGG-----GYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSK 334 + + ++A + G G G G GS++G G G G+ S Sbjct: 2227 HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQS 2286 Query: 335 AAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQ 394 ++ G G + + +H SG+ + SY ++ S S Sbjct: 2287 SSYGQQGSGSGQSPSRGRHGSGS----------------GHSSSYGQHGSGSG------- 2323 Query: 395 PQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAA----ASPAWAAAQQRSHPAMS-PGTPG 449 ++++G G ++G G + Q + S + ++ H + S + G Sbjct: 2324 ---WSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRG 2380 Query: 450 PTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPG-GSYGPPGPQRYPIGIQGRT 508 G S GS +G H SP P G +G Q G Sbjct: 2381 ERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSG 2440 Query: 509 PGAMAGMQYPQQQDSGDATW---KETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHL 565 G + + P + SG ++ +E+ YGQ G S + S Q Sbjct: 2441 SG-WSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSC 2499 Query: 566 PPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSG 625 S GYG + + P H ++ PS SG Sbjct: 2500 GQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG--SGQSPGHGQRGSGSRQSPSYGRHGSG 2557 Query: 626 SIDDLPTGTEATLSSAVSASGS-TSSQGDQSNPAQ--------SPFSPHASPHLSSIPGG 676 S +G + S G SS G S+ +Q S + H S S G Sbjct: 2558 SGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGE 2617 Query: 677 PSPSPVGSPV-------GSNQSR--------SGPISPASIPGSQMPPQPPGSQSESSSHP 721 S GS GS QS SG GS + Q S S Sbjct: 2618 RHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGR 2677 Query: 722 ALSQSPMPQERGFMA-------GTQRNPQMAQYGPQQTG-PSMSPHPSPGGQMHAGISSF 773 + S+ P G + G+ + +Q+G S H S GQ Sbjct: 2678 SSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEG 2737 Query: 774 QQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPC 833 + S +YG + S Y R A SG S S+ G G G S++ HG G Q Sbjct: 2738 SSTGQSSSYGHRGSGSSQSSGYGRHGAGSG-QSLSHGRHGSGSGQSSSYGQHGSGSGQSS 2796 Query: 834 G 834 G Sbjct: 2797 G 2797 Score = 79.7 bits (195), Expect = 3e-14 Identities = 152/731 (20%), Positives = 231/731 (31%), Gaps = 116/731 (15%) Query: 209 HSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGG 268 H++ + + + G + +SH+ QC G S P G G G G G G Sbjct: 169 HNSYSGQSSSYGEQN--SDSHQSSGRGQCGSGSGQS-PNYGQHGSGSGQSSSNDTHGSGS 225 Query: 269 GGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYG--GSSAGYGVLSSPRQQGGGMMMGPGG 326 G + + ++ + +G G GYG GS +G + G G Sbjct: 226 GQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQ 285 Query: 327 GGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPS 386 G+ S G G ++ +H SG+ + S+ ++ S S Sbjct: 286 HGSGSRQSLGHGRQGSGSRQSPSHVRHGSGS----------------GHSSSHGQHGSGS 329 Query: 387 APPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPG 446 S + + G G +G G + Q S ++ S + S G Sbjct: 330 ----------SYSYSRGHYESGSGQTSGFGQHESGSGQ----SSGYSKHGSGSGHSSSQG 375 Query: 447 TPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQG 506 G T G++ S ++ YG + + GS G Sbjct: 376 QHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGS--------------G 421 Query: 507 RTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLP 566 ++PG Q+ SG P GQ G PY S Sbjct: 422 QSPG-------HGQRGSGSG--------QSPSSGQHGTGFGRSSSSGPYVS--------- 457 Query: 567 PQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGS 626 + Y + +G+ S G+ + ER S S S Sbjct: 458 -GSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSS 516 Query: 627 IDDLPTGTEATLSSAVSASGSTSS------QGDQSNPAQSPFSPHASPHLSSIPGGPSPS 680 +G+ +L + SGS S + + + S + PH S GP S Sbjct: 517 YGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYES 576 Query: 681 PVG--SPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALS-QSPMPQERGFMAG 737 G S +G +SRSG S GS G S H + S QS + G +G Sbjct: 577 GSGHSSGLGHQESRSGQSSGYGQHGSS-----SGHSSTHGQHGSTSGQSSSCGQHGATSG 631 Query: 738 TQR--------NPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQY 789 + Q ++YG Q +G SP G SS+ Q S + S Sbjct: 632 QSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWS---SSN 688 Query: 790 GPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNR 849 GP G+ S +S G G G S+ HG G S G G +R Sbjct: 689 GPHGSVS--------GQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHG--------SR 732 Query: 850 PFPGNMSSMTPSSPGMSQQ-GGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPG 908 + S SS G+S G G G + + + + + + S S G Sbjct: 733 SGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHG 792 Query: 909 MNQSGLMASSS 919 + SG SSS Sbjct: 793 QHGSGTSCSSS 803 Score = 77.4 bits (189), Expect = 1e-13 Identities = 198/851 (23%), Positives = 288/851 (33%), Gaps = 85/851 (9%) Query: 176 YGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNS 235 YG S GR G C G QSP G S S ++ N G + Sbjct: 179 YGEQNSDSHQSSGR-GQCGS--GSGQSPNYGQHGSGSGQSSS---------NDTHGSGSG 226 Query: 236 QCNHYPGY-SRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGG 294 Q + + + S G G G G G S G G G+ +G + G +++ ++++ G Sbjct: 227 QSSGFSQHKSSSGQSSGYSQHGSGSGHS-SGYGQHGSRSGQSSRGERHRSSSGSSSSYGQ 285 Query: 295 GGGG---GYGGSSAGYGVLSSPRQ----QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRF 347 G G G G G SP G G G G+ S + G G + Sbjct: 286 HGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQT 345 Query: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407 +G QH SG+ + S + S ++ S S Q ++ ++ G Sbjct: 346 SGFGQHESGSGQSSGY---SKHGSGSGHSSSQGQHGSTSGQASSSGQ-HGSSSRQSSSYG 401 Query: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467 ++A+ G+ + + SP S + S G G GRS S P V Sbjct: 402 QHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSS--GPYVSGS 459 Query: 468 PQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDAT 527 G G + S + SS Y +G G G G Q + + G + Sbjct: 460 GYSSGFGHH-ESSSEHSSGYT--QHGSGSGHSSGHGQHGSRSG-----QSSRGERQGSSA 511 Query: 528 WKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMS 587 + YGQ G G + S Q P PS+ + +Q S Sbjct: 512 GSSS------SYGQHGSGSRQSLGHSRHGSGSGQSPS--------PSRGRHESGSRQSSS 557 Query: 588 --QEGYG---TRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAV 642 GYG + S+ P G + L QE S G +G +T Sbjct: 558 YGPHGYGSGRSSSRGPYESGSGHSSGLG--HQESRSGQSSGYGQ-HGSSSGHSSTHGQHG 614 Query: 643 SASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIP 702 S SG +SS G A S S H S GS G + SR S Sbjct: 615 STSGQSSSCGQHG--ATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFG-H 671 Query: 703 GSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPS-MSPHPS 761 S GS SS+ P S S G +G+ ++ +Q+G + S H S Sbjct: 672 SSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGS 731 Query: 762 PGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISAN 821 GQ S S +YG S + R + SG S S G G S++ Sbjct: 732 RSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSG-HSPSRVRHGSSSGHSSS 790 Query: 822 NQMHGQGP--SQPCGAVPLGRMPSAGM-QNRPFPGNMSSMTPSSPG-MSQQGGPGMGPPM 877 + HG G S CG G ++G Q+ G S S+ G S QG G Sbjct: 791 HGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQ 850 Query: 878 PTV-----NRKAQEAAAAVMQAAANSAQSR------QGSFPGMNQSGLMASSSPYSQPMN 926 + + Q ++ ++A++ A R G PG Q G + SP S + Sbjct: 851 SSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSP-SYGRH 909 Query: 927 NSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESK-LPLPLKADGKEEGTPQPESK 985 S S ++ + + + S S G S G+S G Q S+ Sbjct: 910 GSGSGRSSSSGRHG------SGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSR 963 Query: 986 SKKSSSSTTTG 996 S +SS S G Sbjct: 964 SGQSSRSEQHG 974 Score = 77.4 bits (189), Expect = 1e-13 Identities = 172/755 (22%), Positives = 248/755 (32%), Gaps = 114/755 (15%) Query: 100 QHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAV 159 QHG ++ G+ + G + + G+ G + G G G+ Sbjct: 2135 QHGSRSGQSSRGE----------RHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPS 2184 Query: 160 PGGGGGPAAVPEFNNYYGSAAPASGGPG---GRAG--PCFDQH---GGQQSP----GMGM 207 G G + + +GS + S G R+G F QH G S G G Sbjct: 2185 RGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS 2244 Query: 208 MHSASAAAAGAPGSMDPL---QNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGG 264 H S G+ + S G +S H G S+ + G G G G G Sbjct: 2245 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGR 2304 Query: 265 GGGGGGA----GAGGAGAGAVAAAAAAAAAAAGGGGGG----------GYGGSSAGYGVL 310 G G G G G+G+G +++ + + G G GY +G G Sbjct: 2305 HGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHS 2364 Query: 311 SSPRQQGGGMMMGPGGG--GAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSP 368 SS Q G G G++S S ++ G G ++ G QH SG+ SP Sbjct: 2365 SSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQ-------SP 2417 Query: 369 SPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAA 428 SP +G + SS S P +++ G G ++G+G + Q Sbjct: 2418 SPSRGRHGSGSGQSSSYS----PYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQ---- 2469 Query: 429 SPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYP 488 S + S + + G G T G+S G + S Q SS Sbjct: 2470 SSGYGQHGSSSGHSSTHGQHGSTSGQSSSC---------------GQHGASSGQSSSH-- 2512 Query: 489 GGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYC 548 G +G Q G QG G G Q+ SG P YG+ G Sbjct: 2513 -GQHGSGSSQSSGYGRQGSGSGQSPGHG---QRGSGSR--------QSPSYGRHG----- 2555 Query: 549 QQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHED 608 G S L + + +S Q S +G+ S G+ Sbjct: 2556 -SGSGRSSSSGQHGSGLGESSGFGHHESSSG----QSSSYSQHGSGSGHSSGYGQHGSRS 2610 Query: 609 LNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPA----QSPFSP 664 + ER S S +G+ + SGS S + + S Sbjct: 2611 GQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQ 2670 Query: 665 HASPHLSSIPGGPSPSPVG--SPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPA 722 H S S GP S +G S G ++S SG S S GS Q S+S Sbjct: 2671 HGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS--- 2727 Query: 723 LSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSP----HPSPGGQMHAGISSFQQSNS 778 QS + G G Q + YG + +G S S H + GQ + S Sbjct: 2728 -GQSSTFDQEGSSTG-----QSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQ 2781 Query: 779 SGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPG 813 S +YG S G YS+ + SG SY G Sbjct: 2782 SSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGG 2816 Score = 58.9 bits (141), Expect = 5e-08 Identities = 199/891 (22%), Positives = 292/891 (32%), Gaps = 134/891 (15%) Query: 633 GTEATLSSAVSASGSTSSQGDQ------SNPAQSPFSPHASPHLSSIPGGPSPSPVGSPV 686 G+ + SS GS S Q + S+ + S + H S S+ G S Sbjct: 248 GSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGS------ 301 Query: 687 GSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQ 746 GS QS S + S G GS S S +S Q GF + Q + Sbjct: 302 GSRQSPSH-VRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSG 360 Query: 747 YGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGP---QMSQYGPQGNYSRPPAYSG 803 Y +G S H S GQ H S Q++SSG +G Q S YG + SR + G Sbjct: 361 YSKHGSG---SGHSSSQGQ-HGSTSG--QASSSGQHGSSSRQSSSYGQHESASRHSSGRG 414 Query: 804 VPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFP---------GN 854 S+ SG PG G + GQ PS GR S+G P+ G+ Sbjct: 415 QHSSG-SGQSPGHGQRGSGS--GQSPSSGQHGTGFGRSSSSG----PYVSGSGYSSGFGH 467 Query: 855 MSSMTPSSPGMSQQGGP----------GMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQG 904 S + S G +Q G G + + +A + + + SRQ Sbjct: 468 HESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQS 527 Query: 905 SFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSS---------AASVGL 955 + SG S SP S+ + S S ++ P+ +S ++ +G Sbjct: 528 LGHSRHGSGSGQSPSP-SRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGH 586 Query: 956 ADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWV 1015 + S S + G Q S S +SSS G + G Sbjct: 587 QESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQS 646 Query: 1016 DRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGT 1075 RY ++GS P+ G+ D + G + N ++ + G Sbjct: 647 SRY----GQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSS-GF 701 Query: 1076 SSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSG-----S 1130 + S Y Q+ G G Q ++SG Sbjct: 702 GHKSGSGQSSGYSQH--------GSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYG 753 Query: 1131 LQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSF 1190 G + QS+G G +P+ HG + G SS+ H + S S Sbjct: 754 QHGSGSHQSSGHGRQGSGSGH----SPSRVRHGSSS----GHSSSHGQHGSGTSCSSSC- 804 Query: 1191 PKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQD 1250 Y+ G G+ + G + +S F +QG+ ++S Sbjct: 805 ---------GHYESGSGQASGFGQHESGSGQ----GYSQHGSASGHFSSQGRHGSTS--- 848 Query: 1251 MYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQ 1310 QS S + GQ YG H G+ G G SGQ P G + Q Sbjct: 849 --GQSSSSGQHDSSSGQSSS--YGQHESASHHASGRGRHGSG--SGQSPGHGQRGSGSGQ 902 Query: 1311 QPNYKRH--------MDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYG------------ 1350 P+Y RH G +G + + G + + SS Q Y Q+G Sbjct: 903 SPSYGRHGSGSGRSSSSGRHGSGSGQSSG--FGHKSSSGQSSGYTQHGSGSGHSSSYEQH 960 Query: 1351 GSYSGPDRRPIQ-GQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAA 1409 GS SG R Q G S G G Q+ G Q G QS S + + Sbjct: 961 GSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLG-HGQHGSGSGQSPSPSRGRHGSGSG 1019 Query: 1410 RNDMPYPYQNRQGPGGPTQAPPY-PGMNRTDDMMVPDQRINHESQWPSHVS 1459 ++ PY R G G + PY G + + + R S + H S Sbjct: 1020 QSSSYGPY--RSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGS 1068 Score = 49.7 bits (117), Expect = 3e-05 Identities = 84/399 (21%), Positives = 128/399 (32%), Gaps = 67/399 (16%) Query: 24 QQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLG 83 Q + H H + H H Q + Q Q Q S+ Sbjct: 2469 QSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ 2528 Query: 84 GAGGG-APQPGP----DMEQPQHG----GAKDSAAGGQADPPGPPLLSKPG-----DEDD 129 G+G G +P G + P +G G+ S++ GQ G L G Sbjct: 2529 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH---GSGLGESSGFGHHESSSG 2585 Query: 130 APPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGR 189 + G G G G++ + G + +GS + S G G R Sbjct: 2586 QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHG-R 2644 Query: 190 AGPCFDQHGGQQSPGMGMMHSAS----AAAAGAPGSMDPLQN-----SHEGYPNSQCNHY 240 G Q + G G+ HS+S + +G S P ++ S G S H Sbjct: 2645 QGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHS 2704 Query: 241 PGYSRPGAGGG--------GGGGGGG------GGGSGGGGGGGGAGAGGAGAGAVAAAAA 286 YS+ G+G G G G G +G G G+G + + A Sbjct: 2705 SAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGA 2764 Query: 287 AAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQR 346 + + G G G S+ YG G G G ++ S+ +GS G+ Sbjct: 2765 GSGQSLSHGRHGSGSGQSSSYG------------QHGSGSGQSSGYSQHGSGSGQDGYSY 2812 Query: 347 FAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSP 385 G + H G++ SY S+P +SP Sbjct: 2813 CKGGSNHDGGSS--------------GSYFLSFPSSTSP 2837 Score = 43.9 bits (102), Expect = 0.002 Identities = 81/328 (24%), Positives = 110/328 (33%), Gaps = 59/328 (17%) Query: 1126 ANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDV 1185 ++S G + QS G G + P+P+ HG + G+SS+ S + S Sbjct: 2390 SSSYGQHGSGSRQSLGHGQHGSGSG--QSPSPSRGRHGSGS----GQSSSYSPYGSGSGW 2443 Query: 1186 SDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPN 1245 S S PY+ G +G E G + SS T GQ + Sbjct: 2444 SSS----------RGPYESGSGHSSGLGHR--ESRSGQSSGYGQHGSSSGHSSTHGQHGS 2491 Query: 1246 SSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQP 1305 +S QS S GQ S + YG+Q G SGQ P G + Sbjct: 2492 TS-----GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ----GSGSGQSPGHGQRG 2542 Query: 1306 GLYPQQPNYKRHMDGMYGPPAKRHEGD-------MYNMQYSSQQQEMYNQYG-------- 1350 Q P+Y RH G + G + + SS Q Y+Q+G Sbjct: 2543 SGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG 2602 Query: 1351 ----GSYSGPDRR-PIQGQYPYPYSRERMQGPGQIQTHGIPPQ-----------MMGGPL 1394 GS SG R G S G G Q+ G Q G L Sbjct: 2603 YGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGL 2662 Query: 1395 QSSSSEGPQQNMWAARNDMPYPYQNRQG 1422 SSS G Q + R+ PY++R G Sbjct: 2663 GHSSSHG-QHGSGSGRSSSRGPYESRLG 2689 Score = 31.6 bits (70), Expect = 8.9 Identities = 63/270 (23%), Positives = 85/270 (31%), Gaps = 29/270 (10%) Query: 1121 QPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQG-GRSSTISVH 1179 Q P+ GS G + T + + G + + + G G G SS H Sbjct: 201 QSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQH 260 Query: 1180 DPFSDVSDSSFPKRNSMTPNAPYQQ---GMSMPDVMGRMPYEPNKDPFGGMRKVPGS--S 1234 S S R+S ++ Y Q G GR + P +R GS S Sbjct: 261 GSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSP-SHVRHGSGSGHS 319 Query: 1235 EPFMTQGQMPNSSMQDMYNQSPSGAMSNLGM-----GQRQQFPYGASYDRRHEPYGQQ-- 1287 G + S + +S SG S G GQ + S GQ Sbjct: 320 SSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGS 379 Query: 1288 YPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYN 1347 GQ SGQ Q Y Q + RH G +H S Q + Sbjct: 380 TSGQASSSGQHGSSSRQSSSYGQHESASRHSSG-----RGQHSS-------GSGQSPGHG 427 Query: 1348 QYGGSYSGPDRRPIQGQYPYPYSRERMQGP 1377 Q G SG + P GQ+ + R GP Sbjct: 428 QRG---SGSGQSPSSGQHGTGFGRSSSSGP 454 >gi|62865637 AT rich interactive domain 3C (BRIGHT- like) [Homo sapiens] Length = 412 Score = 102 bits (253), Expect = 5e-21 Identities = 98/347 (28%), Positives = 157/347 (45%), Gaps = 30/347 (8%) Query: 973 DGKEEGTPQPESKSKKSSSST-------TTGEKITKVYELGNEPERKLWVDRYLTFMEER 1025 + EE P + S SS T E+ ++YEL +P+RK ++D +FM++R Sbjct: 71 EAAEESRPGAQGPSSPSSQPPGLHPHEWTYEEQFKQLYELDADPKRKEFLDDLFSFMQKR 130 Query: 1026 GSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTS-SSAASSLK 1084 G+PV+ +P + K+ LDL+ L+ V GGL +V K WRE+ L++ T+ +SAA +L+ Sbjct: 131 GTPVNRVPIMAKQVLDLYALFRLVTAKGGLVEVINRKVWREVTRGLSLPTTITSAAFTLR 190 Query: 1085 KQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNS 1144 QY++YL+ +EC+ R P E+ + D+ ++ + A L G P G+ Sbjct: 191 TQYMKYLYPYECE-TRALSSPGELQAAIDSNRREGRRQAYTAT--PLFGLAGPPPRGAQD 247 Query: 1145 MAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPN--APY 1202 A PG P T +S Q G +S + H + +S S K S PN Sbjct: 248 PALGPGPAPPATQSSPGPAQ------GSTSGLPAH-ACAQLSPSPIKKEESGIPNPCLAL 300 Query: 1203 QQGMSMPDVMGRM-PYEP--NKDPFGGMRKVPGSSEP--FMTQGQMP--NSSMQDMYNQS 1255 G+++ ++ P EP + G P P F+ +G++P + N + Sbjct: 301 PVGLALGPTREKLAPEEPPEKRAVLMGPMDPPRPCMPPSFLPRGKVPLREERLDGPLNLA 360 Query: 1256 PSGAMS-NLGMGQRQQFPYGASYDRRHEPYGQQYPGQ--GPPSGQPP 1299 SG S N+ + G + RR Q P PPS PP Sbjct: 361 GSGISSINMALEINGVVYTGVLFARRQPVPASQGPTNPAPPPSTGPP 407 >gi|109255251 loricrin [Homo sapiens] Length = 312 Score = 99.4 bits (246), Expect = 3e-20 Identities = 95/296 (32%), Positives = 117/296 (39%), Gaps = 43/296 (14%) Query: 66 QQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPG 125 Q++Q Q P+ + GG GGG G GG GG G S G Sbjct: 4 QKKQPTPQPPVDCVKTSGGGGGGGGSGG--------GGCGFFGGGGSG---GGSSGSGCG 52 Query: 126 DEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASG- 184 G GG G G +G G GGG +++ GS+ SG Sbjct: 53 YSGGGGYSGGGCGGGSSGGGGGGGIG---------GCGGGSGGSVKYSGGGGSSGGGSGC 103 Query: 185 -GPGGRAGPCFDQHGGQQSPG-MGMMHSASAAAAGAPGSMDPLQNSHEGYPNS--QCNHY 240 GG CF GG S G G S ++G G + G+ QC Y Sbjct: 104 FSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSG--GGSGCFSSGGGGFSGQAVQCQSY 161 Query: 241 PGYSRPGAGGGGGG----GGGGG---GGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAA- 292 G S G+ GGG G GGGGG G SGGG G GG +GG+G+G V++ + A Sbjct: 162 GGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAP 221 Query: 293 --GGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSK---AAAGSAAGG 343 GGG GG S G G SS GGG G GGG + S + GS GG Sbjct: 222 QPSYGGGSSGGGGSGGSGCFSS---GGGGGSSGCGGGSSGIGSGCIISGGGSVCGG 274 Score = 89.7 bits (221), Expect = 3e-17 Identities = 67/212 (31%), Positives = 89/212 (41%), Gaps = 25/212 (11%) Query: 247 GAGGGGGGGGGGGGGSGGGGGGGGAGAGGAG--AGAVAAAAAAAAAAAGGGGGGGYGGSS 304 G GGGGG GGGG G GGGG GGG+ G G G + ++GGGGGGG GG Sbjct: 22 GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCG 81 Query: 305 AGYGVLSSPRQQGGGMMMG-------PGGGGAASLSKAAAGSAAGGFQRFA----GQNQH 353 G G S + GGG G GGGG+ S GS+ GG F+ G + Sbjct: 82 GGSG--GSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGG 139 Query: 354 PSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAA 413 SG + + + +SYGG SS S S G+ G + Sbjct: 140 GSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGG-----SGCFSSGGGGGSVCGYSGGGS 194 Query: 414 GMGLGKDMGAQYAAASPAWAAAQQRSHPAMSP 445 G G G G + + ++QQ + + +P Sbjct: 195 GCGGGSSGG-----SGSGYVSSQQVTQTSCAP 221 Score = 89.0 bits (219), Expect = 5e-17 Identities = 68/227 (29%), Positives = 88/227 (38%), Gaps = 18/227 (7%) Query: 82 LGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMG--EPAG 139 +GG GGG+ G ++ GG+ +G + G G + G G Sbjct: 77 IGGCGGGS---GGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGG 133 Query: 140 GRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGG 199 G G G + GGGG + +Y G + SGG G CF GG Sbjct: 134 GGSSGGGSGCFSS--------GGGGFSGQAVQCQSYGGVS---SGGSSGGGSGCFSSGGG 182 Query: 200 QQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGG 259 S G S G+ G S + + C P Y G+ GGGG GG G Sbjct: 183 GGSV-CGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGG-GSSGGGGSGGSGC 240 Query: 260 GGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAG 306 SGGGGG G G G +G G+ + + GG GGG GGSS G Sbjct: 241 FSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVG 287 Score = 85.1 bits (209), Expect = 7e-16 Identities = 76/243 (31%), Positives = 94/243 (38%), Gaps = 41/243 (16%) Query: 152 TQQPPV----AVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGM 207 T QPPV GGGGG + ++G G G G + GG G G Sbjct: 9 TPQPPVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCG--YSGGGGYSGGGCGG 66 Query: 208 MHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGG------GGGG 261 S G G C G S +GGGG GGG GGGG Sbjct: 67 GSSGGGGGGGIGG----------------CGGGSGGSVKYSGGGGSSGGGSGCFSSGGGG 110 Query: 262 SG----GGGG--GGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQ 315 SG GGGG GGG+G +G G ++ + ++GGGG G YG +SS Sbjct: 111 SGCFSSGGGGSSGGGSGCFSSGGGG-SSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGS 169 Query: 316 QGGGM-MMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRS 374 GGG GGGG + + GS GG + + S T Q +P P S Sbjct: 170 SGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVT--QTSCAPQP---S 224 Query: 375 YGG 377 YGG Sbjct: 225 YGG 227 >gi|55750053 atrophin-1 [Homo sapiens] Length = 1190 Score = 98.2 bits (243), Expect = 8e-20 Identities = 157/662 (23%), Positives = 216/662 (32%), Gaps = 132/662 (19%) Query: 374 SYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWA 433 S G + P Y P PP P P S A+ + G M + A Sbjct: 152 SQGPARP-YHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPP 210 Query: 434 AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYG 493 A HP + PG G G G PM P G + P ++P S G Sbjct: 211 GAPP-PHPQLYPGGTG---GVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSG 266 Query: 494 PPG-----PQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYC 548 G P P+G G P A +P + +PP + ++ Sbjct: 267 ASGAPPTKPPTTPVG-GGNLPSAPPPANFPHVTPN-----------LPPPPALRPLNN-- 312 Query: 549 QQGQQPYYSQQPQPPHLP-PQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHE 607 P QP P HLP P A Q M G P LAP Sbjct: 313 ASASPPGLGAQPLPGHLPSPHAM------------GQGMGGLPPGPEKGPTLAPS----- 355 Query: 608 DLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFS---- 663 P SLP S S P + SS+ SA+ S+SS S+ + P S Sbjct: 356 ---------PHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALP 406 Query: 664 --PHASPHLSSIP---------------------GGPSPSPVGSPVGSNQSRSGPISPAS 700 PH+ P +S+ G P P P G + ++ + GP P++ Sbjct: 407 SYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPST 466 Query: 701 IPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHP 760 G+Q PP S+ H Q Q++ Q+ GP P PHP Sbjct: 467 --GAQSTAHPP----VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP--PGAFPHP 518 Query: 761 SPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGP-GPGMGIS 819 GG H + S S G+ P P G PP +S V S S +GP GP + S Sbjct: 519 LEGGSSHHA-HPYAMSPSLGSLRPY-----PPGPAHLPPPHSQV-SYSQAGPNGPPVSSS 571 Query: 820 ANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPT 879 +N+ S PC + SP QG P PP+PT Sbjct: 572 SNSSSSTSQGSYPC-------------------------SHPSPSQGPQGAPYPFPPVPT 606 Query: 880 VNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASS------------SPYSQPMNN 927 V + + + A++ A + S PG G A S P S P Sbjct: 607 VTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFR 666 Query: 928 SSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLP-LPLKADGKEEGTPQPESKS 986 + + + P + +VG + G S LP LP G P ++ Sbjct: 667 TGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQI 726 Query: 987 KK 988 K+ Sbjct: 727 KQ 728 Score = 86.3 bits (212), Expect = 3e-16 Identities = 120/488 (24%), Positives = 171/488 (35%), Gaps = 91/488 (18%) Query: 545 SGYCQQGQQPYYSQQPQPPHLPPQAQ---YLPSQSQQRYQPQQDMSQEGYGTRSQPPLA- 600 SG Q +PY+ PP PP Q P Q + ++P ++ GY +PP + Sbjct: 149 SGLSQGPARPYHP----PPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSR 204 Query: 601 -----PGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQS 655 PG P P P +G + P +A S G G Q Sbjct: 205 MFQAPPGAP---------PPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNG--GKQH 253 Query: 656 NPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPG--SQMPPQPP-- 711 P +P S +S G P P +PVG S P PA+ P +PP P Sbjct: 254 PPPTTPISVSSS----GASGAPPTKPPTTPVGGGNLPSAP-PPANFPHVTPNLPPPPALR 308 Query: 712 GSQSESSSHPALSQSPMPQER-----------GFMAGTQRNPQMAQYGPQQTGPSMSPHP 760 + S+S P L P+P G G ++ P +A P P+ S P Sbjct: 309 PLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAP-SPHSLPPASSSAP 367 Query: 761 SPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISA 820 +P + SS + +S + S P PA +PS +S P P + Sbjct: 368 APPMRFPYSSSSSSSAAASSSSSSSSSSASPF------PASQALPSYPHSFPPPTSLSVS 421 Query: 821 NNQMHGQGPSQPCGAV---------PLGRM-PSAGMQNRPFPGNMSSMTPSSPGMSQQGG 870 N PS P AV P GR+ ++ PFP + + + + P +S Sbjct: 422 NQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHH 481 Query: 871 PGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSS 930 ++ Q+ Q NS G+FP P+ SS Sbjct: 482 HHQQQQQQQQQQQQQQQQQ--QQHHGNSGPPPPGAFP---------------HPLEGGSS 524 Query: 931 LMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQ--PESKSKK 988 A PY+M+P S+G PG + LP P + P P S S Sbjct: 525 ---HHAHPYAMSP--------SLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSN 573 Query: 989 SSSSTTTG 996 SSSST+ G Sbjct: 574 SSSSTSQG 581 Score = 77.8 bits (190), Expect = 1e-13 Identities = 158/681 (23%), Positives = 204/681 (29%), Gaps = 125/681 (18%) Query: 106 DSAAG---GQADPPGPPLLSKPGDED-DAPPKMGEPAGGRYEHPGLGALGTQQP------ 155 DS++G G A P PP L P + D+ P+ +P HP + G P Sbjct: 146 DSSSGLSQGPARPYHPPPLFPPSPQPPDSTPR--QPEASFEPHPSVTPTGYHAPMEPPTS 203 Query: 156 -------------PVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQS 202 P PGG GG + P G AA + GGP G G Q Sbjct: 204 RMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNG---------GKQHP 254 Query: 203 PGMGMMHSASAAAAGAPGSMDPLQ-----NSHEGYPNSQCNHY-PGYSRPGAGGGGGGGG 256 P + +S+ A+GAP + P N P + H P P A Sbjct: 255 PPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNN-- 312 Query: 257 GGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYG-GSSAGYGVLSSPRQ 315 A A G GA + A G G GG G G + SP Sbjct: 313 --------------ASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHS 358 Query: 316 QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATP-TLNQLLTS-----PS 369 P S +++ SAA + + S A+P +Q L S P Sbjct: 359 LPPASSSAPAPPMRFPYSSSSSSSAAAS----SSSSSSSSSASPFPASQALPSYPHSFPP 414 Query: 370 PMMRSYGGSYPEYSSPSAPP-------PPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMG 422 P S P+Y+ PS P PPP P + A A G G Sbjct: 415 PTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGP-------FPPSTG 467 Query: 423 AQYAAASPAWA-----AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNP 477 AQ A P QQ+ P P P L G GS+ Sbjct: 468 AQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP-LEG-GSSH 525 Query: 478 HSQPQQSSPYPGGSYG-PPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMP 536 H+ P SP G PPGP P + + Y Q +G P Sbjct: 526 HAHPYAMSPSLGSLRPYPPGP--------AHLPPPHSQVSYSQAGPNG-----------P 566 Query: 537 PQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQY---------LPSQSQQRYQPQQDMS 587 P S QG P P P P A Y S + S Sbjct: 567 PVSSSSNSSSSTSQGSYP--CSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASS 624 Query: 588 QEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGS 647 GY T S P P + P GS TGT +G Sbjct: 625 PAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKP--GSPPSFRTGTPPGYRGTSPPAGP 682 Query: 648 TSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMP 707 + + P P L S+P P+ G P+ + Q + P P S +P Sbjct: 683 GTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVP 742 Query: 708 ----PQPPGSQSESSSHPALS 724 P PP + SH + S Sbjct: 743 PARSPSPPPKVVDVPSHASQS 763 Score = 77.8 bits (190), Expect = 1e-13 Identities = 138/623 (22%), Positives = 200/623 (32%), Gaps = 126/623 (20%) Query: 251 GGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVL 310 GG GG G G GGG + GG G + + G G Sbjct: 222 GGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASG------------ 269 Query: 311 SSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSP 370 A +K GG L ++P P Sbjct: 270 -------------------APPTKPPTTPVGGG-------------------NLPSAPPP 291 Query: 371 MMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASP 430 ++P + +P+ PPPP +P + A+A+ G Q + MG P Sbjct: 292 ------ANFP-HVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPP 344 Query: 431 AWAAAQQRSHPAMSPGTPGPTMGRSQGSPMD-PMVMKRPQLYGMGSNPHSQPQQSSPYPG 489 ++ A SP + P + PM P S+ S +SP+P Sbjct: 345 ---GPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPA 401 Query: 490 GSYGPPGPQRYP----IGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVS 545 P P +P + + + P +Y Q A W + PP YG+ + Sbjct: 402 SQALPSYPHSFPPPTSLSVSNQPP------KYTQPSLPSQAVWSQG-PPPPPPYGRLLAN 454 Query: 546 GYCQQGQQPYYSQQPQPPHLPPQAQY----LPSQSQQRYQPQQDMSQEGYGTRSQPPLAP 601 G P + H P + Q QQ+ Q QQ Q+ +G PP P Sbjct: 455 SNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP--P 512 Query: 602 GK-PNHEDLNLIQQERPSSLPDLSGSIDDLPTG--------TEATLSSA-------VSAS 645 G P+ + P ++ GS+ P G ++ + S A S+S Sbjct: 513 GAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSS 572 Query: 646 GSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISP-----AS 700 S+SS S P P SP P G P P P PV + + S +S AS Sbjct: 573 NSSSSTSQGSYPCSHP-SPSQGPQ-----GAPYPFP---PVPTVTTSSATLSTVIATVAS 623 Query: 701 IPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHP 760 P PPG P+ G+ G +P + G SP Sbjct: 624 SPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPG---SPPSFRTGTPPGYRGTSPPA 680 Query: 761 SPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISA 820 PG +F+ + + GP + GP G S PP P+A S GP + + Sbjct: 681 GPG--------TFKPGSPTVGPGP-LPPAGPSGLPSLPPP----PAAPAS--GPPLSATQ 725 Query: 821 NNQMHGQGPSQPCGAVPLGRMPS 843 Q + P VP R PS Sbjct: 726 IKQEPAEEYETPESPVPPARSPS 748 Score = 70.9 bits (172), Expect = 1e-11 Identities = 118/519 (22%), Positives = 173/519 (33%), Gaps = 112/519 (21%) Query: 1104 PPPEVFSTGDTKKQPKLQPPS---PANSGSLQGP-----------QTPQSTGSNSMAEVP 1149 PPP F P L PP P N+ S P +P + G P Sbjct: 289 PPPANFP----HVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPP 344 Query: 1150 GDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMP 1209 G K PT A +PH P + + P+S S SS +S + ++ Sbjct: 345 GPEKGPTLAPSPHS--LPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSS-------- 394 Query: 1210 DVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQ 1269 + PF + +P F + S+ Y Q + + G Sbjct: 395 ----------SASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPP 444 Query: 1270 QFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRH 1329 PYG R +PG PPS G Q +P + H H Sbjct: 445 PPPYG-----RLLANSNAHPGPFPPST-----GAQSTAHPPVSTHHHH-----------H 483 Query: 1330 EGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQM 1389 + Q QQQ+ Q+ G+ SGP P G +P+P ++G H Sbjct: 484 QQQQQQQQQQQQQQQQQQQHHGN-SGP---PPPGAFPHP-----LEGGSSHHAH------ 528 Query: 1390 MGGPLQSSSSEGPQQNMWAARNDMPYPYQ----NRQGPGGPTQAPPYPGMNRTDDMMVPD 1445 P S S G + +P P+ ++ GP GP P N + Sbjct: 529 ---PYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGP---PVSSSSNSSSSTSQGS 582 Query: 1446 QRINHESQWPSHVSQRQPY--------MSSSASMQPI-----TRPPQPSYQTPPSLPNHI 1492 +H S PS Q PY +SSA++ + + P +PP P + Sbjct: 583 YPCSHPS--PSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYG 640 Query: 1493 SRAPSPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPT---------SQVTGPPPQPP- 1542 RAPSP +++ + P P + T P S GP P PP Sbjct: 641 KRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPA 700 Query: 1543 -PIRREITFPPGSVEASQPVLK--QRRKITSKDIVTPEA 1578 P PP + AS P L Q ++ +++ TPE+ Sbjct: 701 GPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPES 739 Score = 62.4 bits (150), Expect = 5e-09 Identities = 73/279 (26%), Positives = 92/279 (32%), Gaps = 67/279 (24%) Query: 13 TVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQ 72 + G A P HHHHH QQQQQQQQQQQQQQQQQ Sbjct: 465 STGAQSTAHPPVSTHHHHHQ-----------------------QQQQQQQQQQQQQQQQQ 501 Query: 73 QHPISNNNSLGGA------GGGAPQPGPDMEQPQHGGAKDSAAG-------------GQA 113 QH ++ GA GG + P P G + G QA Sbjct: 502 QHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQA 561 Query: 114 DPPGPPLLSKPGDEDDA---------PPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGG 164 P GPP+ S P P G Y P + + T ++ Sbjct: 562 GPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTV---- 617 Query: 165 GPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDP 224 A V Y +A+P P G+ P SPG + G+P S Sbjct: 618 -IATVASSPAGYKTASPPGPPPYGKRAP---------SPGAYKTATPPGYKPGSPPSF-- 665 Query: 225 LQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSG 263 + GY + PG +PG+ G G G SG Sbjct: 666 RTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG 704 Score = 59.7 bits (143), Expect = 3e-08 Identities = 109/462 (23%), Positives = 156/462 (33%), Gaps = 100/462 (21%) Query: 1107 EVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPAS-TPHGQM 1165 E ST KQ + + S + S P+ ++ + P DL S G Sbjct: 60 EEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSS 119 Query: 1166 TPM---QGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKD 1222 P Q RS++ S++ P S +DS S P PY P + P P+ Sbjct: 120 DPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHP----PPLFPPSPQPPDST 175 Query: 1223 PFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQF--PYGASYDRR 1280 P + P +S + + +P+G + + + F P GA Sbjct: 176 P------------------RQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAP---- 213 Query: 1281 HEPYGQQYPG------QGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGP-PAKRHEGDM 1333 P+ Q YPG GPP G P GG + GP K+H Sbjct: 214 -PPHPQLYPGGTGGVLSGPPMG--PKGGGA-------------ASSVGGPNGGKQHPPPT 257 Query: 1334 YNMQYSSQQQEMYNQYGGSYSGPDRRPIQG----QYPYPYSRERMQGPGQIQTHGIPPQM 1389 + SS G + P P+ G P P + + T +PP Sbjct: 258 TPISVSSS-----GASGAPPTKPPTTPVGGGNLPSAPPPANFPHV-------TPNLPPPP 305 Query: 1390 MGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPG--------GPTQAP-PYPGMNRTDD 1440 PL ++S+ P +P P+ QG G GPT AP P+ + Sbjct: 306 ALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSS 365 Query: 1441 MMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPAS 1500 P R + S S + SSS+S P P+ Q PS P+ P P S Sbjct: 366 APAPPMRFPYSSSSSSSAAASSSSSSSSSSASPF-----PASQALPSYPHSF---PPPTS 417 Query: 1501 FQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPP 1542 S+ N+ P LPS + GPPP PP Sbjct: 418 L--SVSNQPPKYTQPSLPSQAVWS----------QGPPPPPP 447 >gi|55750041 atrophin-1 [Homo sapiens] Length = 1190 Score = 98.2 bits (243), Expect = 8e-20 Identities = 157/662 (23%), Positives = 216/662 (32%), Gaps = 132/662 (19%) Query: 374 SYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWA 433 S G + P Y P PP P P S A+ + G M + A Sbjct: 152 SQGPARP-YHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPP 210 Query: 434 AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYG 493 A HP + PG G G G PM P G + P ++P S G Sbjct: 211 GAPP-PHPQLYPGGTG---GVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSG 266 Query: 494 PPG-----PQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYC 548 G P P+G G P A +P + +PP + ++ Sbjct: 267 ASGAPPTKPPTTPVG-GGNLPSAPPPANFPHVTPN-----------LPPPPALRPLNN-- 312 Query: 549 QQGQQPYYSQQPQPPHLP-PQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHE 607 P QP P HLP P A Q M G P LAP Sbjct: 313 ASASPPGLGAQPLPGHLPSPHAM------------GQGMGGLPPGPEKGPTLAPS----- 355 Query: 608 DLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFS---- 663 P SLP S S P + SS+ SA+ S+SS S+ + P S Sbjct: 356 ---------PHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALP 406 Query: 664 --PHASPHLSSIP---------------------GGPSPSPVGSPVGSNQSRSGPISPAS 700 PH+ P +S+ G P P P G + ++ + GP P++ Sbjct: 407 SYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPST 466 Query: 701 IPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHP 760 G+Q PP S+ H Q Q++ Q+ GP P PHP Sbjct: 467 --GAQSTAHPP----VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP--PGAFPHP 518 Query: 761 SPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGP-GPGMGIS 819 GG H + S S G+ P P G PP +S V S S +GP GP + S Sbjct: 519 LEGGSSHHA-HPYAMSPSLGSLRPY-----PPGPAHLPPPHSQV-SYSQAGPNGPPVSSS 571 Query: 820 ANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPT 879 +N+ S PC + SP QG P PP+PT Sbjct: 572 SNSSSSTSQGSYPC-------------------------SHPSPSQGPQGAPYPFPPVPT 606 Query: 880 VNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASS------------SPYSQPMNN 927 V + + + A++ A + S PG G A S P S P Sbjct: 607 VTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFR 666 Query: 928 SSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLP-LPLKADGKEEGTPQPESKS 986 + + + P + +VG + G S LP LP G P ++ Sbjct: 667 TGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQI 726 Query: 987 KK 988 K+ Sbjct: 727 KQ 728 Score = 86.3 bits (212), Expect = 3e-16 Identities = 120/488 (24%), Positives = 171/488 (35%), Gaps = 91/488 (18%) Query: 545 SGYCQQGQQPYYSQQPQPPHLPPQAQ---YLPSQSQQRYQPQQDMSQEGYGTRSQPPLA- 600 SG Q +PY+ PP PP Q P Q + ++P ++ GY +PP + Sbjct: 149 SGLSQGPARPYHP----PPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSR 204 Query: 601 -----PGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQS 655 PG P P P +G + P +A S G G Q Sbjct: 205 MFQAPPGAP---------PPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNG--GKQH 253 Query: 656 NPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPG--SQMPPQPP-- 711 P +P S +S G P P +PVG S P PA+ P +PP P Sbjct: 254 PPPTTPISVSSS----GASGAPPTKPPTTPVGGGNLPSAP-PPANFPHVTPNLPPPPALR 308 Query: 712 GSQSESSSHPALSQSPMPQER-----------GFMAGTQRNPQMAQYGPQQTGPSMSPHP 760 + S+S P L P+P G G ++ P +A P P+ S P Sbjct: 309 PLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAP-SPHSLPPASSSAP 367 Query: 761 SPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISA 820 +P + SS + +S + S P PA +PS +S P P + Sbjct: 368 APPMRFPYSSSSSSSAAASSSSSSSSSSASPF------PASQALPSYPHSFPPPTSLSVS 421 Query: 821 NNQMHGQGPSQPCGAV---------PLGRM-PSAGMQNRPFPGNMSSMTPSSPGMSQQGG 870 N PS P AV P GR+ ++ PFP + + + + P +S Sbjct: 422 NQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHH 481 Query: 871 PGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSS 930 ++ Q+ Q NS G+FP P+ SS Sbjct: 482 HHQQQQQQQQQQQQQQQQQ--QQHHGNSGPPPPGAFP---------------HPLEGGSS 524 Query: 931 LMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQ--PESKSKK 988 A PY+M+P S+G PG + LP P + P P S S Sbjct: 525 ---HHAHPYAMSP--------SLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSN 573 Query: 989 SSSSTTTG 996 SSSST+ G Sbjct: 574 SSSSTSQG 581 Score = 77.8 bits (190), Expect = 1e-13 Identities = 158/681 (23%), Positives = 204/681 (29%), Gaps = 125/681 (18%) Query: 106 DSAAG---GQADPPGPPLLSKPGDED-DAPPKMGEPAGGRYEHPGLGALGTQQP------ 155 DS++G G A P PP L P + D+ P+ +P HP + G P Sbjct: 146 DSSSGLSQGPARPYHPPPLFPPSPQPPDSTPR--QPEASFEPHPSVTPTGYHAPMEPPTS 203 Query: 156 -------------PVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQS 202 P PGG GG + P G AA + GGP G G Q Sbjct: 204 RMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNG---------GKQHP 254 Query: 203 PGMGMMHSASAAAAGAPGSMDPLQ-----NSHEGYPNSQCNHY-PGYSRPGAGGGGGGGG 256 P + +S+ A+GAP + P N P + H P P A Sbjct: 255 PPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNN-- 312 Query: 257 GGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYG-GSSAGYGVLSSPRQ 315 A A G GA + A G G GG G G + SP Sbjct: 313 --------------ASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHS 358 Query: 316 QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATP-TLNQLLTS-----PS 369 P S +++ SAA + + S A+P +Q L S P Sbjct: 359 LPPASSSAPAPPMRFPYSSSSSSSAAAS----SSSSSSSSSASPFPASQALPSYPHSFPP 414 Query: 370 PMMRSYGGSYPEYSSPSAPP-------PPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMG 422 P S P+Y+ PS P PPP P + A A G G Sbjct: 415 PTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGP-------FPPSTG 467 Query: 423 AQYAAASPAWA-----AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNP 477 AQ A P QQ+ P P P L G GS+ Sbjct: 468 AQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP-LEG-GSSH 525 Query: 478 HSQPQQSSPYPGGSYG-PPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMP 536 H+ P SP G PPGP P + + Y Q +G P Sbjct: 526 HAHPYAMSPSLGSLRPYPPGP--------AHLPPPHSQVSYSQAGPNG-----------P 566 Query: 537 PQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQY---------LPSQSQQRYQPQQDMS 587 P S QG P P P P A Y S + S Sbjct: 567 PVSSSSNSSSSTSQGSYP--CSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASS 624 Query: 588 QEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGS 647 GY T S P P + P GS TGT +G Sbjct: 625 PAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKP--GSPPSFRTGTPPGYRGTSPPAGP 682 Query: 648 TSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMP 707 + + P P L S+P P+ G P+ + Q + P P S +P Sbjct: 683 GTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVP 742 Query: 708 ----PQPPGSQSESSSHPALS 724 P PP + SH + S Sbjct: 743 PARSPSPPPKVVDVPSHASQS 763 Score = 77.8 bits (190), Expect = 1e-13 Identities = 138/623 (22%), Positives = 200/623 (32%), Gaps = 126/623 (20%) Query: 251 GGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVL 310 GG GG G G GGG + GG G + + G G Sbjct: 222 GGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASG------------ 269 Query: 311 SSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSP 370 A +K GG L ++P P Sbjct: 270 -------------------APPTKPPTTPVGGG-------------------NLPSAPPP 291 Query: 371 MMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASP 430 ++P + +P+ PPPP +P + A+A+ G Q + MG P Sbjct: 292 ------ANFP-HVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPP 344 Query: 431 AWAAAQQRSHPAMSPGTPGPTMGRSQGSPMD-PMVMKRPQLYGMGSNPHSQPQQSSPYPG 489 ++ A SP + P + PM P S+ S +SP+P Sbjct: 345 ---GPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPA 401 Query: 490 GSYGPPGPQRYP----IGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVS 545 P P +P + + + P +Y Q A W + PP YG+ + Sbjct: 402 SQALPSYPHSFPPPTSLSVSNQPP------KYTQPSLPSQAVWSQG-PPPPPPYGRLLAN 454 Query: 546 GYCQQGQQPYYSQQPQPPHLPPQAQY----LPSQSQQRYQPQQDMSQEGYGTRSQPPLAP 601 G P + H P + Q QQ+ Q QQ Q+ +G PP P Sbjct: 455 SNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP--P 512 Query: 602 GK-PNHEDLNLIQQERPSSLPDLSGSIDDLPTG--------TEATLSSA-------VSAS 645 G P+ + P ++ GS+ P G ++ + S A S+S Sbjct: 513 GAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSS 572 Query: 646 GSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISP-----AS 700 S+SS S P P SP P G P P P PV + + S +S AS Sbjct: 573 NSSSSTSQGSYPCSHP-SPSQGPQ-----GAPYPFP---PVPTVTTSSATLSTVIATVAS 623 Query: 701 IPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHP 760 P PPG P+ G+ G +P + G SP Sbjct: 624 SPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPG---SPPSFRTGTPPGYRGTSPPA 680 Query: 761 SPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISA 820 PG +F+ + + GP + GP G S PP P+A S GP + + Sbjct: 681 GPG--------TFKPGSPTVGPGP-LPPAGPSGLPSLPPP----PAAPAS--GPPLSATQ 725 Query: 821 NNQMHGQGPSQPCGAVPLGRMPS 843 Q + P VP R PS Sbjct: 726 IKQEPAEEYETPESPVPPARSPS 748 Score = 70.9 bits (172), Expect = 1e-11 Identities = 118/519 (22%), Positives = 173/519 (33%), Gaps = 112/519 (21%) Query: 1104 PPPEVFSTGDTKKQPKLQPPS---PANSGSLQGP-----------QTPQSTGSNSMAEVP 1149 PPP F P L PP P N+ S P +P + G P Sbjct: 289 PPPANFP----HVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPP 344 Query: 1150 GDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMP 1209 G K PT A +PH P + + P+S S SS +S + ++ Sbjct: 345 GPEKGPTLAPSPHS--LPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSS-------- 394 Query: 1210 DVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQ 1269 + PF + +P F + S+ Y Q + + G Sbjct: 395 ----------SASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPP 444 Query: 1270 QFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRH 1329 PYG R +PG PPS G Q +P + H H Sbjct: 445 PPPYG-----RLLANSNAHPGPFPPST-----GAQSTAHPPVSTHHHH-----------H 483 Query: 1330 EGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQM 1389 + Q QQQ+ Q+ G+ SGP P G +P+P ++G H Sbjct: 484 QQQQQQQQQQQQQQQQQQQHHGN-SGP---PPPGAFPHP-----LEGGSSHHAH------ 528 Query: 1390 MGGPLQSSSSEGPQQNMWAARNDMPYPYQ----NRQGPGGPTQAPPYPGMNRTDDMMVPD 1445 P S S G + +P P+ ++ GP GP P N + Sbjct: 529 ---PYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGP---PVSSSSNSSSSTSQGS 582 Query: 1446 QRINHESQWPSHVSQRQPY--------MSSSASMQPI-----TRPPQPSYQTPPSLPNHI 1492 +H S PS Q PY +SSA++ + + P +PP P + Sbjct: 583 YPCSHPS--PSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYG 640 Query: 1493 SRAPSPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPT---------SQVTGPPPQPP- 1542 RAPSP +++ + P P + T P S GP P PP Sbjct: 641 KRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPA 700 Query: 1543 -PIRREITFPPGSVEASQPVLK--QRRKITSKDIVTPEA 1578 P PP + AS P L Q ++ +++ TPE+ Sbjct: 701 GPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPES 739 Score = 62.4 bits (150), Expect = 5e-09 Identities = 73/279 (26%), Positives = 92/279 (32%), Gaps = 67/279 (24%) Query: 13 TVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQ 72 + G A P HHHHH QQQQQQQQQQQQQQQQQ Sbjct: 465 STGAQSTAHPPVSTHHHHHQ-----------------------QQQQQQQQQQQQQQQQQ 501 Query: 73 QHPISNNNSLGGA------GGGAPQPGPDMEQPQHGGAKDSAAG-------------GQA 113 QH ++ GA GG + P P G + G QA Sbjct: 502 QHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQA 561 Query: 114 DPPGPPLLSKPGDEDDA---------PPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGG 164 P GPP+ S P P G Y P + + T ++ Sbjct: 562 GPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTV---- 617 Query: 165 GPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDP 224 A V Y +A+P P G+ P SPG + G+P S Sbjct: 618 -IATVASSPAGYKTASPPGPPPYGKRAP---------SPGAYKTATPPGYKPGSPPSF-- 665 Query: 225 LQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSG 263 + GY + PG +PG+ G G G SG Sbjct: 666 RTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG 704 Score = 59.7 bits (143), Expect = 3e-08 Identities = 109/462 (23%), Positives = 156/462 (33%), Gaps = 100/462 (21%) Query: 1107 EVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPAS-TPHGQM 1165 E ST KQ + + S + S P+ ++ + P DL S G Sbjct: 60 EEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSS 119 Query: 1166 TPM---QGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKD 1222 P Q RS++ S++ P S +DS S P PY P + P P+ Sbjct: 120 DPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHP----PPLFPPSPQPPDST 175 Query: 1223 PFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQF--PYGASYDRR 1280 P + P +S + + +P+G + + + F P GA Sbjct: 176 P------------------RQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAP---- 213 Query: 1281 HEPYGQQYPG------QGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGP-PAKRHEGDM 1333 P+ Q YPG GPP G P GG + GP K+H Sbjct: 214 -PPHPQLYPGGTGGVLSGPPMG--PKGGGA-------------ASSVGGPNGGKQHPPPT 257 Query: 1334 YNMQYSSQQQEMYNQYGGSYSGPDRRPIQG----QYPYPYSRERMQGPGQIQTHGIPPQM 1389 + SS G + P P+ G P P + + T +PP Sbjct: 258 TPISVSSS-----GASGAPPTKPPTTPVGGGNLPSAPPPANFPHV-------TPNLPPPP 305 Query: 1390 MGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPG--------GPTQAP-PYPGMNRTDD 1440 PL ++S+ P +P P+ QG G GPT AP P+ + Sbjct: 306 ALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSS 365 Query: 1441 MMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPAS 1500 P R + S S + SSS+S P P+ Q PS P+ P P S Sbjct: 366 APAPPMRFPYSSSSSSSAAASSSSSSSSSSASPF-----PASQALPSYPHSF---PPPTS 417 Query: 1501 FQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPP 1542 S+ N+ P LPS + GPPP PP Sbjct: 418 L--SVSNQPPKYTQPSLPSQAVWS----------QGPPPPPP 447 >gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] Length = 1604 Score = 96.7 bits (239), Expect = 2e-19 Identities = 237/1002 (23%), Positives = 306/1002 (30%), Gaps = 202/1002 (20%) Query: 93 GPDMEQPQHGGAKDSAAGGQADPPGPP------LLSKPGDEDDAPPKMGEPAGGRYEHPG 146 GP ++ G G+ PPG P L PGD P G+ G PG Sbjct: 429 GPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDK--GSSGIPG 486 Query: 147 LGALGTQQPPVAVPGGGGGPAAV----PE-FNNYY------------GSAAPASGGPG-- 187 G + V G G P V PE F N+ G PA G PG Sbjct: 487 KEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQ 546 Query: 188 ---GRAG-PCFD-------QH--------GGQQSPGMGMM----------------HSAS 212 G G PC QH G SPG G+ + Sbjct: 547 GIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGE 606 Query: 213 AAAAGAPGSMDPLQNSH-EGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGA 271 A AG+PG P+ + +G C P S G G G G G G Sbjct: 607 AGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGF 666 Query: 272 GAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAA- 330 G G A AG G G G++ G+ P QG G G G Sbjct: 667 GLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTA 726 Query: 331 --SLSKAAAGSAAGGFQRFAGQNQHPSG----------------ATPTLNQLLTSPSPMM 372 SL A Q Q P G P L + P P Sbjct: 727 CPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPG 786 Query: 373 RSYGGSYPEYSSPS-----------APPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDM 421 R G E +P PP P + +Q + A G G + Sbjct: 787 RGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPP 846 Query: 422 GAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQP 481 G P G PG SQG + + P L+ MGS+ P Sbjct: 847 GRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLW-MGSSWQPGP 905 Query: 482 QQSSPYPGGSYGPPGPQRYPIGIQG--------RTPGAMAGM------QYPQQQDSGDAT 527 Q P G GPPGP P G+QG PG A + Q+ + GD Sbjct: 906 QG----PPGIPGPPGPPGVP-GLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCV 960 Query: 528 WKET----FWLMPPQYGQQGVSGY-----CQQG----QQPYYSQQ--------------- 559 + + + + G QG+ G C Q ++P + Sbjct: 961 QGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSP 1020 Query: 560 --PQPPHLPPQ-AQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQER 616 P PP LP Q + P + P + G+ P PG L + ++ Sbjct: 1021 GLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDK 1080 Query: 617 ----PSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSS 672 P P G+ P G L G T S G++ P P S L Sbjct: 1081 GEPGPPGQPGYPGATG--PPG----LPGIKGERGYTGSAGEKGEP-----GPPGSEGLPG 1129 Query: 673 IPGGPSPSPVGSPVGSNQSRS-----------GPISPASIPGSQMPPQPPGSQSESSSHP 721 PG P P G++ + GP P PG P PPG Q+E S Sbjct: 1130 PPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEG 1189 Query: 722 ALSQSPMPQERG--FMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMH-AGISSFQ-QSN 777 S +P G G Q + + P + P P G G F+ ++ Sbjct: 1190 IRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTG 1249 Query: 778 SSGTYGPQ--MSQYGPQGNYSRPPAYSGVPSA--SYSGPGPGMGISANNQMHGQGPSQPC 833 G GP+ + GP G+ RP A G P A PGP + GP+ Sbjct: 1250 HPGLPGPKGDCGKPGPPGSTGRPGA-EGEPGAMGPQGRPGPPGHVGPPGPPGQPGPA-GI 1307 Query: 834 GAVPL-------GRMPSAGMQNRPFPGNMSSMTPSSPG----MSQQGGPG----MGPPMP 878 AV L G AG+ +P P P PG ++G PG GPP P Sbjct: 1308 SAVGLKGDRGATGERGLAGLPGQPGPPGHPG-PPGEPGTDGAAGKEGPPGKQGFYGPPGP 1366 Query: 879 TVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSP 920 K AA Q + R G G +SG M P Sbjct: 1367 ----KGDPGAAG--QKGQAGEKGRAGMPGGPGKSGSMGPVGP 1402 Score = 72.0 bits (175), Expect = 6e-12 Identities = 124/479 (25%), Positives = 142/479 (29%), Gaps = 76/479 (15%) Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLL-------------SKPGDEDD- 129 G G PGP E+ G S G PPGPP + KPG D Sbjct: 1171 GKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDP 1230 Query: 130 ---APPKMGEPAG--GRYEHPGL-GALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPAS 183 PP + P G G+ HPGL G G P PG G P A E P + Sbjct: 1231 GPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKP-GPPGSTGRPGAEGE---------PGA 1280 Query: 184 GGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPL-QNSHEGYPNSQCNHYPG 242 GP GR GP H G P G A +A G G + G P PG Sbjct: 1281 MGPQGRPGP--PGHVGPPGP-PGQPGPAGISAVGLKGDRGATGERGLAGLPGQP--GPPG 1335 Query: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG 302 + P G G G G G G G G G A A AG GG G G Sbjct: 1336 HPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSG 1395 Query: 303 SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAG--GFQRFAGQNQHPSGATPT 360 S G ++G GP G + G +RF Q Sbjct: 1396 SMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERM 1455 Query: 361 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGM----- 415 PM + P P P P S G+Q G+ Sbjct: 1456 AYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPG 1515 Query: 416 --GLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGM 473 G D+G A + PG PGP QG P YG Sbjct: 1516 TKGEKGDIGIGIAGENGL-------------PGPPGP-----QGPPG----------YGK 1547 Query: 474 GSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETF 532 QQ P G GPPGP P P G +QQ T K F Sbjct: 1548 MGATGPMGQQGIP---GIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKTMKGPF 1603 Score = 68.9 bits (167), Expect = 5e-11 Identities = 180/807 (22%), Positives = 226/807 (28%), Gaps = 179/807 (22%) Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPG--------------DEDD 129 G G PGP E+ G A G PPG + PG E Sbjct: 806 GLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKG 865 Query: 130 APPKMGEPA------------GGRYEHPGLGALGTQQP-PVAVPG--GGGGPAAVPEFNN 174 + GEP G PGL + QP P PG G GP VP Sbjct: 866 PRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQG 925 Query: 175 YYG-SAAPASGG-----------------------PGGRAGPCF----DQHGGQQSPGM- 205 G + P G G RA P + + G Q PG+ Sbjct: 926 VPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVP 985 Query: 206 ---------------------GMMHSASAAAAGAPGSMDPL----QNSHEGYPNSQCNHY 240 G G+PG P Q EG P + + Sbjct: 986 GLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPG 1045 Query: 241 P--GYSRPGAGGGGGGGG--GGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGG 296 P PG G G G G G G G G G G A G G Sbjct: 1046 PPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKG 1105 Query: 297 GGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPS- 355 GY GS+ G P + G+ PG G S G Q F GQ P Sbjct: 1106 ERGYTGSAGEKGEPGPPGSE--GLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGP 1163 Query: 356 GATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGM 415 P + SP P PS P P P A G G Sbjct: 1164 PGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGK 1223 Query: 416 -GLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMG 474 GL D G A P PG PGP G P P RP G Sbjct: 1224 PGLRGDPG---PAGPPGLMGPPGFKGKTGHPGLPGPK--GDCGKPGPPGSTGRP---GAE 1275 Query: 475 SNPHSQPQQSSPYPGGSYGPPGPQRYP-------IGIQG--------------RTPGAMA 513 P + Q P P G GPPGP P +G++G PG Sbjct: 1276 GEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPG 1335 Query: 514 GMQYPQQQDSGDATWKE------TFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPP 567 P + + A KE F+ P G G +G Q + + P P Sbjct: 1336 HPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPG--- 1392 Query: 568 QAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKP----------NHEDLNLIQQERP 617 S S P + G+ P +PG P N++++ ++ Sbjct: 1393 -----KSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEI 1447 Query: 618 SSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSP-----------HA 666 + D + +++A G G P +P SP Sbjct: 1448 IKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPG-APGSPGLPGQIGREGRQG 1506 Query: 667 SPHLSSIPG-------------------GPSPSPVGSPVGSNQSRSGPISPASIPGSQMP 707 P + +PG GP P P G P +GP+ IPG P Sbjct: 1507 LPGVRGLPGTKGEKGDIGIGIAGENGLPGP-PGPQGPPGYGKMGATGPMGQQGIPGIPGP 1565 Query: 708 PQP---PGSQSESSSHPALSQSPMPQE 731 P P PG + PM Q+ Sbjct: 1566 PGPMGQPGKAGHCNPSDCFGAMPMEQQ 1592 Score = 66.6 bits (161), Expect = 3e-10 Identities = 178/785 (22%), Positives = 246/785 (31%), Gaps = 136/785 (17%) Query: 246 PGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSA 305 P G G G G G GG G G G G G G G + Sbjct: 388 PSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAG 447 Query: 306 GYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAA----------GGFQRFAGQNQHPS 355 G P G G+ PG G K GS+ G G+ P Sbjct: 448 EPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPC 507 Query: 356 GATPTLNQLLTSPSPMMRSYG--GSYPEYSSPSAPPPPPSQPQSQ---------AAAAGA 404 PTL P G G P P P P Q + + Sbjct: 508 EVCPTL------PEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSS 561 Query: 405 AAGGQQAAAGMGLGKDMGA--------QYAAASPAWAAAQ---QRSHPAMSPGTPGPT-- 451 G Q + G D+G+ A P + + PA SPG PGP Sbjct: 562 VVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGP 621 Query: 452 --MGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTP 509 + ++G P +P P L + + P P G G PGP + G+ G+ Sbjct: 622 AGIKGAKGEPCEPC----PALSNLQDG--DVRVVALPGPSGEKGEPGPPGF--GLPGKQG 673 Query: 510 GAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGY-CQQGQQPYYSQQPQPPHLPPQ 568 A Q+ D+G+ T P G+ G+SG QG ++ P Sbjct: 674 KAGERGLKGQKGDAGNPGDPGT----PGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPS 729 Query: 569 AQYLPSQSQQR---YQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSG 625 Q + R P+ + EG G PGKP LP + G Sbjct: 730 LQGTVTDMAGRPGQPGPKGEQGPEGVG-------RPGKPGQ-----------PGLPGVQG 771 Query: 626 SIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSP 685 P G + G G Q P +P L I G P P P Sbjct: 772 -----PPGLK----------GVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGP 816 Query: 686 VGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMA 745 G ++ P + G+ P PPG+ S S P G T Sbjct: 817 TGEKGAQGSP----GVKGATGPVGPPGA----------SVSGPPGRDGQQGQTGLRGTPG 862 Query: 746 QYGP--QQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSG 803 + GP ++ P PS G + +G+ + G + Q GPQG PP G Sbjct: 863 EKGPRGEKGEPGECSCPSQGDLIFSGM-----PGAPGLWMGSSWQPGPQG----PPGIPG 913 Query: 804 VPSASYSGPG-PGM-GISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPS 861 P PG PG+ G+ NN + P QP LG +P + G+ + Sbjct: 914 PPGP----PGVPGLQGVPGNNGL----PGQPGLTAELGSLPIEQHLLKSICGDCVQGQRA 965 Query: 862 SPG----MSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPG-MNQSGLMA 916 PG ++G G+ P +P ++ AQ + A + PG + GL Sbjct: 966 HPGYLVEKGEKGDQGI-PGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPG 1024 Query: 917 SSS-PYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGK 975 P + + + PP + P + S GL + GE L L D Sbjct: 1025 PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQ--GERGL-TGLTGDKG 1081 Query: 976 EEGTP 980 E G P Sbjct: 1082 EPGPP 1086 Score = 44.3 bits (103), Expect = 0.001 Identities = 58/196 (29%), Positives = 67/196 (34%), Gaps = 41/196 (20%) Query: 82 LGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPP-LLSKPGDEDDAPPKMGEPAG- 139 L G G +PGP + G + A G PGPP + PG PP PAG Sbjct: 1253 LPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPG-----PPGQPGPAGI 1307 Query: 140 ---------GRYEHPGLGALGTQQPPVAVPG--------GGGGPAAVPEFNNYYGSAAPA 182 G GL L Q P PG G G P +YG P Sbjct: 1308 SAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGP- 1366 Query: 183 SGGPG-----GRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQC 237 G PG G+AG + G PG G S S G PG + H G P Sbjct: 1367 KGDPGAAGQKGQAG----EKGRAGMPG-GPGKSGSMGPVGPPGPAG--ERGHPGAPGPSG 1419 Query: 238 NHYPGYSRPGAGGGGG 253 + PG PG G G Sbjct: 1420 S--PGL--PGVPGSMG 1431 Score = 33.9 bits (76), Expect = 1.8 Identities = 77/327 (23%), Positives = 109/327 (33%), Gaps = 66/327 (20%) Query: 1123 PSPANSGSLQGPQ-TPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDP 1181 P P G +QGPQ P + G + +PG PP P Q +P G + +T V P Sbjct: 782 PGPPGRG-VQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSP--GVKGATGPVGPP 838 Query: 1182 FSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQG 1241 + VS P QQG + G+R PG P +G Sbjct: 839 GASVSG---------PPGRDGQQGQT------------------GLRGTPGEKGPRGEKG 871 Query: 1242 QMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYG 1301 + S + SG G+ G+S+ +P Q PG P G P Sbjct: 872 EPGECSCPSQGDLIFSGMPGAPGLWM------GSSW----QPGPQGPPGIPGPPGPPGVP 921 Query: 1302 GHQ--PGL--YPQQPNYKRHMDGMYGPPAKRH----------EGDMYNMQYSSQQQEMYN 1347 G Q PG P QP + + P ++H +G + Y ++ E + Sbjct: 922 GLQGVPGNNGLPGQPGLTAELGSL---PIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGD 978 Query: 1348 QYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMW 1407 Q G D Q R R + + G P G + S GP Sbjct: 979 QGIPGVPGLDN---CAQCFLSLERPRAEEARGDNSEGDP-----GCVGSPGLPGPPGLPG 1030 Query: 1408 AARNDMPYPYQNRQGPGGPTQAPPYPG 1434 + P + GP GP P +PG Sbjct: 1031 QRGEEGPPGMRGSPGPPGPIGPPGFPG 1057 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 95.1 bits (235), Expect = 7e-19 Identities = 245/986 (24%), Positives = 313/986 (31%), Gaps = 168/986 (17%) Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAG----GQADPPGPPLLSKP-GDED-DAPPKMGEP 137 G G A PG Q G K G PGPP P G E D PP + Sbjct: 635 GDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGL 694 Query: 138 AG--GRYEHPGL-GALGTQQPP-----VAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGR 189 G G PG+ G LG Q PP PG GG P E P GP G+ Sbjct: 695 RGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGK 754 Query: 190 AGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMD-------------PLQNSHEGYPNSQ 236 GP G P G PG P + G P + Sbjct: 755 DGP-----NGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGA- 808 Query: 237 CNHYPGYSRPGAGGGGGGGGGGG--GGSGGGGGGGGAG-AGGAGAGAVAAAAAAAAAAAG 293 PG+ PG G G G G G G G G G AG AG + + Sbjct: 809 ----PGF--PGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPR 862 Query: 294 GGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQH 353 G G G G+ P QG +GP G +K G A G AG Sbjct: 863 MPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEG--AHGAPGAAGNPGA 920 Query: 354 PSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAA 413 P + PS PP P + G++ AA Sbjct: 921 P-----------------------GHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAA 957 Query: 414 G----MGLGKDMGAQYAAASPAWAAAQQRSHPAM--SPGTPGP-----TMGRSQGS---P 459 G G G A P + P + SPG PGP G+ +GS Sbjct: 958 GEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCA 1017 Query: 460 MDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGA--MAGMQY 517 + +K + G P S + P G + GPPGP P G +G +PG+ + G Sbjct: 1018 LGGQCVKGDR--GAPGIPGSPGSRGDPGIGVA-GPPGPSG-PPGDKG-SPGSRGLPGFPG 1072 Query: 518 PQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQ------PQPPHLPPQAQY 571 PQ D PP G+ G+S G ++ P PP LP Sbjct: 1073 PQGPAGRDGAPGNPGERGPP--GKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPG---- 1126 Query: 572 LPSQSQQRYQPQQDMSQ--EGYGTRSQPPLAPGKPNHEDLNLIQQER----------PSS 619 LP + P + + EG + PP PG P Q ER Sbjct: 1127 LPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQG 1186 Query: 620 LPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPA-QSPFSPHASPHLSSIPG--- 675 P + G + P G A +G+ G Q +P + P P L IPG Sbjct: 1187 HPGVPGFMG--PPGNPGP-PGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEG 1243 Query: 676 ----GPSPSPVGSPVGSNQ----SRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSP 727 P P G P + + G P G PG + ES + Q Sbjct: 1244 KEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEG 1303 Query: 728 MPQERGFMAGT-QRNPQMAQYGPQQTGPSMSP-HPSPGGQMHAGISSFQQSNSSGTYG-P 784 +P + G T + PQ + P + G SP P P G + Q S G G P Sbjct: 1304 LPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSG-------TPGQKGSKGENGSP 1356 Query: 785 QMSQY-GPQGNYSRP-----PAYSGVP----SASYSGPGPGMGISANNQMHGQGPSQPCG 834 + + GP+G P P GVP + G GI + G G QP Sbjct: 1357 GLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPG-GKGQPGD 1415 Query: 835 AVPLGRMPSAGMQN-RPFPGNMSSMTPSSPGMSQQGGPGM---GPPMPTVNRKAQE---- 886 G G+ + PG + P P Q G PG+ P M T+ R QE Sbjct: 1416 PGIPGHKGHTGLMGPQGLPGENGPVGPPGP-PGQPGFPGLRGESPSMETLRRLIQEELGK 1474 Query: 887 --------AAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQP-MNNSSSLMNTQAP 937 A + A S+Q R G + GL + P +P L P Sbjct: 1475 QLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGP 1534 Query: 938 --PYSMAPAMVNSSAASVGLADMMSP 961 P A + A VGL M P Sbjct: 1535 IGPKGERGAKGDPGAPGVGLRGEMGP 1560 Score = 80.1 bits (196), Expect = 2e-14 Identities = 155/664 (23%), Positives = 202/664 (30%), Gaps = 149/664 (22%) Query: 84 GAGGGAPQPG----PDMEQPQHGGAKDSAAG--GQADPPGPPLLSK---PGDED------ 128 G G PG P PQ +D A G G+ PPG P LS PGD + Sbjct: 1054 GPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDV 1113 Query: 129 --DAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGP 186 D PP PGL L + VPG G + + P GP Sbjct: 1114 CNDCPPGP----------PGLPGLPGFKGDKGVPGKPGREGTEGKKGE---AGPPGLPGP 1160 Query: 187 GGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRP 246 G AGP S GA G + Q +G+P PG+ P Sbjct: 1161 PGIAGP-----------------QGSQGERGADGEVG--QKGDQGHPG-----VPGFMGP 1196 Query: 247 GAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAG 306 G G G G +G G G G G + G G G G Sbjct: 1197 PGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGE 1256 Query: 307 YGVLSSPRQQGGGMMMGPGG-GGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLL 365 G P G GP G G S A G GQ P T Sbjct: 1257 PGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDT----- 1311 Query: 366 TSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGM----GLGKDM 421 P+ G P+ P PP P S + GQ+ + G GL + Sbjct: 1312 -GPT------GPQGPQ--GPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFL 1362 Query: 422 GAQYAAASPAWAAAQQRSHPAMSPGTPG-------PTMGRSQGSPMDPMVMKRPQLYGMG 474 G + P + PG PG P + +G P P + G Sbjct: 1363 GPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHK 1422 Query: 475 SNPHSQPQQSSPYPGGSYGPPGPQRYP--IGIQGRTPGAMAGMQYPQQQDSGDATWKETF 532 + Q P G GPPGP P G++G +P +M ++ Q++ G Sbjct: 1423 GHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESP-SMETLRRLIQEELGKQLETRLA 1481 Query: 533 WL---MPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQE 589 +L MPP Y + QG+ P PP P ++ Sbjct: 1482 YLLAQMPPAYMKSS------QGR-------PGPPGPP--------------------GKD 1508 Query: 590 GYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTS 649 G R+ P PG+P L E PS + G Sbjct: 1509 GLPGRAGPMGEPGRPGQGGL-----EGPSG---------------------PIGPKGERG 1542 Query: 650 SQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSP-VGSNQSRSGPISPASIPGSQMPP 708 ++GD P P + PG P + G P + Q +GP +PG PP Sbjct: 1543 AKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPG---PP 1599 Query: 709 QPPG 712 PPG Sbjct: 1600 GPPG 1603 Score = 79.7 bits (195), Expect = 3e-14 Identities = 205/871 (23%), Positives = 262/871 (30%), Gaps = 163/871 (18%) Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS-----------KPGD-----E 127 G G G E G D G+A P GPP L PG+ E Sbjct: 813 GVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGE 872 Query: 128 DDAPPKMGEPAGGRYEHPG-LGALGTQQPPVA--------VPGGGGGPAAVPEFNNYYGS 178 P GEP G PG LG G PP A PG G P A S Sbjct: 873 KGDPGLPGEP--GLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPS 930 Query: 179 AAPAS-GGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQC 237 P S G PG R P D G++ +A G+PG + P G P + Sbjct: 931 GPPGSVGAPGLRGTPGKDGERGEKG---------AAGEEGSPGPVGP-----RGDPGA-- 974 Query: 238 NHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGG 297 PG PG G G G G GS G G G A A G G Sbjct: 975 ---PGL--PGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGA 1029 Query: 298 GGYGGSSA-----GYGVLSSPRQQGG-GMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQN 351 G GS G GV P G G PG G + G G+ Sbjct: 1030 PGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGER 1089 Query: 352 QHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQA 411 P P L+ LL SP + + PP PP P G+ Sbjct: 1090 GPPG--KPGLSSLL-SPGDI-----NLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPG 1141 Query: 412 AAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMS-------------PGTPGPTMGRSQGS 458 G K P A Q S PG PG G Sbjct: 1142 REGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPG-----FMGP 1196 Query: 459 PMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYP 518 P +P + G P Q SP G GPPGPQ P G+ G + G + Sbjct: 1197 PGNPGPPGADGIAGAAGPPGIQ---GSP---GKEGPPGPQG-PSGLPG-----IPGEEGK 1244 Query: 519 QQQDS-----GDATWKETFWLMPPQ--YGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQY 571 + +D G+ L P+ G G G+ P + LP Q + Sbjct: 1245 EGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQ-EG 1303 Query: 572 LPSQSQQRYQ--PQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDD 629 LP + PQ G ++ P +PG+P PS P GS + Sbjct: 1304 LPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPG-----------PSGTPGQKGSKGE 1352 Query: 630 LPTGTEATLSSAVSASGSTSSQGDQSNPAQS--PFSPHASPHLSSIPGGPS-------PS 680 L + G G++ P + P P P G P P Sbjct: 1353 ---NGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKP-GEPGFKGERGDPGIKGDKGPPG 1408 Query: 681 PVGSP----VGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSP--------M 728 G P + ++ +G + P +PG P PPG + +SP + Sbjct: 1409 GKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLI 1468 Query: 729 PQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQ 788 +E G T+ +AQ P S PG G+ + Sbjct: 1469 QEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLP---------------GR 1513 Query: 789 YGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQN 848 GP G R P G+ GP I + +G G G M G+ Sbjct: 1514 AGPMGEPGR-PGQGGL-------EGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPG 1565 Query: 849 RP-FPGNMSSMTPSSPGMSQQGGPGMGPPMP 878 +P PG P PG + GP P +P Sbjct: 1566 QPGEPGYAKDGLPGIPGPQGETGPAGHPGLP 1596 Score = 58.5 bits (140), Expect = 7e-08 Identities = 131/543 (24%), Positives = 162/543 (29%), Gaps = 89/543 (16%) Query: 388 PPPPPSQPQSQAA-----------AAGAAAGGQQAAAG-MGLGKDMGAQYAAASPAWAAA 435 PPPPP +P + + + A G+ AG MGL G A P A Sbjct: 453 PPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKG-DIGAIGPVGAPG 511 Query: 436 QQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPP 495 + + G G +GS P R GM P + P G GP Sbjct: 512 PKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQ 571 Query: 496 GPQRYPIGIQGRT--PGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQ 553 GP P G GR PG + + F P GQQG G Sbjct: 572 GPPGLP-GPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAG- 629 Query: 554 PYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQ 613 P + P PP Q + Q G+ PP A G E Sbjct: 630 PQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEG----- 684 Query: 614 QERPSSLPDLSGSIDDL-PTGTEATLSSAVSASGSTSSQGDQSNPA-QSPFSPHASPHLS 671 ++ P L L G D+ P G L QG P P P SP L Sbjct: 685 RDGPPGLQGLRGKKGDMGPPGIPGLLGL----------QGPPGPPGVPGPPGPGGSPGLP 734 Query: 672 S---IPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPM 728 PG P P GP P G PP PPG++ E Sbjct: 735 GEIGFPGKPGPP-------------GPTGPPGKDGPNGPPGPPGTKGE------------ 769 Query: 729 PQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQ 788 P ERG + + G Q PG + AG+ G G + Q Sbjct: 770 PGERGEDGLPGKPGLRGEIGEQGLA------GRPGEKGEAGLPG--APGFPGVRGEKGDQ 821 Query: 789 YGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQN 848 G +G P +GP G+ + P P P G G+ Sbjct: 822 -GEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGL-- 878 Query: 849 RPFPGNMSSMTPSSPGMSQQGGPG-MGPPMPT--VNRKAQEAAAAVMQAAANSAQSRQGS 905 P PG+ QG PG +GP PT K QE A AA N Sbjct: 879 -----------PGEPGL--QGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVG 925 Query: 906 FPG 908 PG Sbjct: 926 APG 928 Score = 57.4 bits (137), Expect = 2e-07 Identities = 123/510 (24%), Positives = 158/510 (30%), Gaps = 80/510 (15%) Query: 82 LGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGR 141 + G G + G D E Q G G PPG P PG + A G Sbjct: 1163 IAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNP--GPPGADGIA---------GA 1211 Query: 142 YEHPGL-GALGTQQPPVAVPGGGGGPAAVPEFNNYYG----SAAPASGGPGGRAG-PCFD 195 PG+ G+ G + PP G GP+ +P G P G G+AG P Sbjct: 1212 AGPPGIQGSPGKEGPP-----GPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLP 1266 Query: 196 QHGGQQSPGMGMMHSASAAAAGAPGSMDPL-QNSHEGYPNSQCNHYP-GYSRPGAGGGGG 253 G + P H+ + A G G + EG P + P G P G Sbjct: 1267 GPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPP 1326 Query: 254 GGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSP 313 G G G G G G G G+ + G G G G GV P Sbjct: 1327 GKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKP 1386 Query: 314 RQQG-GGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMM 372 + G G PG G G G G H L P + Sbjct: 1387 GEPGFKGERGDPGIKGDKG---PPGGKGQPGDPGIPGHKGHTG---------LMGPQGL- 1433 Query: 373 RSYGGSYPEYSSPSAPPPPPSQP-----QSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAA 427 P + P PP PP QP + ++ + Q G L + A Sbjct: 1434 -------PGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQ 1486 Query: 428 ASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMG-----SNP----- 477 PA+ + Q PG PGP G P M P G G S P Sbjct: 1487 MPPAYMKSSQG-----RPGPPGPP--GKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKG 1539 Query: 478 --HSQPQQSSPYPG--GSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFW 533 ++ +P G G GPPG P G G + G+ P Q ++G A Sbjct: 1540 ERGAKGDPGAPGVGLRGEMGPPGIPGQP-GEPGYAKDGLPGIPGP-QGETGPAG------ 1591 Query: 534 LMPPQYGQQGVSGYCQQGQQPYYSQQPQPP 563 P G G G C Q Y++ P Sbjct: 1592 -HPGLPGPPGPPGQCDPSQCAYFASLAARP 1620 Score = 39.7 bits (91), Expect = 0.033 Identities = 51/193 (26%), Positives = 65/193 (33%), Gaps = 41/193 (21%) Query: 56 QQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADP 115 Q++ +Q + + Q P + S G G PG D + G + GQ Sbjct: 1469 QEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGL 1528 Query: 116 PGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNY 175 GP P E A G+P PG+G G PP +PG G P Y Sbjct: 1529 EGPSGPIGPKGERGA---KGDPGA-----PGVGLRGEMGPP-GIPGQPGEP-------GY 1572 Query: 176 YGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNS 235 P GP G GP H G P G PG DP S Sbjct: 1573 AKDGLPGIPGPQGETGPA--GHPGLPGP------------PGPPGQCDP----------S 1608 Query: 236 QCNHYPGY-SRPG 247 QC ++ +RPG Sbjct: 1609 QCAYFASLAARPG 1621 Score = 35.8 bits (81), Expect = 0.47 Identities = 68/293 (23%), Positives = 87/293 (29%), Gaps = 70/293 (23%) Query: 76 ISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGP---------------PL 120 + L G G GP Q G + + G PGP P Sbjct: 1298 LPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPG 1357 Query: 121 L----------SKPGD-----EDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGG 165 L +PG+ ++ P K GEP G + E G G + P PGG G Sbjct: 1358 LPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEP-GFKGERGDPGIKGDKGP----PGGKGQ 1412 Query: 166 PA--AVPEFNNYYG----SAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAP 219 P +P + G P GP G GP G PG+ G Sbjct: 1413 PGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGP----PGQPGFPGL----------RGES 1458 Query: 220 GSMDPLQNSHEGYPNSQCNHYPGY--------------SRPGAGGGGGGGG-GGGGGSGG 264 SM+ L+ + Q Y RPG G G G G G G Sbjct: 1459 PSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMG 1518 Query: 265 GGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQG 317 G G G +G + A G G G G G+ P + G Sbjct: 1519 EPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPG 1571 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 94.7 bits (234), Expect = 9e-19 Identities = 221/878 (25%), Positives = 283/878 (32%), Gaps = 199/878 (22%) Query: 82 LGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGR 141 L G GGA GP E G + G PPG KPG++ GEP GR Sbjct: 226 LQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPG-----KPGED-------GEP--GR 271 Query: 142 YEHPG-LGALGTQQPPVAVPGGGGGPAA--VPEFNNYYGS----------AAPASGGPGG 188 +PG +G G+ PG G P A +P + G AP S G G Sbjct: 272 NGNPGEVGFAGS-------PGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAG 324 Query: 189 RAGPC--------------FDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPN 234 GP + G Q +PG H G PG M PL G P Sbjct: 325 PTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAH----GMPGKPGPMGPL-----GIPG 375 Query: 235 SQCNHYPGYSRPGAGGGGG--GGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAA 292 S + +PG PG G G G G G G G G G G+ A A Sbjct: 376 S--SGFPG--NPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAK 431 Query: 293 GGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQ 352 G G G G G SP QG GP G + GF+ AG Sbjct: 432 GPTGSPGTSGPPGSAGPPGSPGPQGS---TGPQG-----IRGQPGDPGVPGFKGEAGPKG 483 Query: 353 HPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAA 412 P + P G P + PP P G++ A Sbjct: 484 EPG------PHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPV--------------GERGA 523 Query: 413 AGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYG 472 G + G + P AQ P S G G SQG P P P G Sbjct: 524 PG-----NRGFPGSDGLPGPKGAQGERGPVGSSGPKG-----SQGDPGRPGEPGLPGARG 573 Query: 473 MGSNPHSQPQQ------SSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDA 526 + NP Q + +P G GPPG IGI+G+ PG+M G+ P + SGD Sbjct: 574 LTGNPGVQGPEGKLGPLGAPGEDGRPGPPG----SIGIRGQ-PGSM-GLPGP-KGSSGD- 625 Query: 527 TWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQ--PQPPHLPPQAQYLPSQSQQRYQPQQ 584 P + G+ G +G Q P + P P PP + + P Sbjct: 626 ---------PGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGL----AGERGEQGPPG 672 Query: 585 DMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSA 644 +G PP GKP + +P G++ L E Sbjct: 673 PTGFQGLPGPPGPPGEGGKPGDQ-----------GVPGDPGAVGPLGPRGERGNPGERGE 721 Query: 645 SGSTSSQGDQSNP-AQSPFSPHASPHLSSIPG--GP--------------SPSPVGSPVG 687 G T G++ P P SP S PG GP +P P G G Sbjct: 722 PGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGG 781 Query: 688 ----SNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMA--GTQRN 741 + +G +PG PP P G E P RG + G++ N Sbjct: 782 IGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGE---------PGPRGLVGPPGSRGN 832 Query: 742 P-QMAQYGPQQ----TGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQ--MSQYGPQGN 794 P + GP GP P PG + G Q +G+ GPQ GP G Sbjct: 833 PGSRGENGPTGAVGFAGP-QGPDGQPGVKGEPGEPG--QKGDAGSPGPQGLAGSPGPHGP 889 Query: 795 YSRPPAYSG----VPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRP 850 P G P + PG + GP+ P G G+ G++ P Sbjct: 890 NGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEP--GKEGPPGLRGDP 947 Query: 851 -FPGNMSSMTPSSP--GMSQQGGPGM-------GPPMP 878 G + P+ P G +G PG GPP P Sbjct: 948 GSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGP 985 Score = 81.6 bits (200), Expect = 8e-15 Identities = 165/671 (24%), Positives = 206/671 (30%), Gaps = 136/671 (20%) Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS-KPGDED-DAPPKMGEPAGGR 141 G G PG E+ + G + G PPGPP KPGD+ P P G R Sbjct: 651 GPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPR 710 Query: 142 YEH--------PGLGALGTQQPPVAV-----PGGGGGPAAVPEFNNYYG-SAAPASGGPG 187 E PG+ L ++ P G GP+ P G P G Sbjct: 711 GERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIA 770 Query: 188 GRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPL----QNSHEGYPNSQCNHYPGY 243 G GP D+ G + G + + A G PG + P +G P + G Sbjct: 771 GTPGPKGDRGGIGEKGAEGT--AGNDGARGLPGPLGPPGPAGPTGEKGEPGPR-----GL 823 Query: 244 SRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGS 303 P G G G G +G G G G G AG G G GS Sbjct: 824 VGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGS 883 Query: 304 SAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPS-----GAT 358 +G P +GG GP G A GF AG+ P G Sbjct: 884 PGPHGPNGVPGLKGGRGTQGPPG--------------ATGFPGSAGRVGPPGPAGAPGPA 929 Query: 359 PTLNQLLTSPSPMMRSYGGSYPEYSS--PSAPPPPPS---------QPQSQAAAAGAAAG 407 L + P +R GS+ P+ PP P QP A Sbjct: 930 GPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTT 989 Query: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467 GQ+ GM G + P PA +PG GPT P P+ Sbjct: 990 GQRGIVGMP-----GQRGERGMPGLPG------PAGTPGKVGPTGATGDKGPPGPV---- 1034 Query: 468 PQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGM-QYPQQQDSGDA 526 P G G PGP+ P G G TPG + + + D G A Sbjct: 1035 ----------------GPPGSNGPVGEPGPEG-PAGNDG-TPGRDGAVGERGDRGDPGPA 1076 Query: 527 TWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDM 586 +P G G G G Q+ P P P ++ +R P Sbjct: 1077 G-------LPGSQGAPGTPG--PVGAPGDAGQRGDPGSRGPIGP--PGRAGKRGLPGPQ- 1124 Query: 587 SQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASG 646 G R K +H D Q+ L G LP G Sbjct: 1125 -----GPRGD------KGDHGDRGDRGQKGHRGFTGLQG----LP-----------GPPG 1158 Query: 647 STSSQGDQSNPAQSPFSPHASPHL---SSIPGGPSP-SPVGSP-VGSNQSRSGPISPASI 701 QG P PF P P S G P P P+G P V + +GP P Sbjct: 1159 PNGEQGSAGIPG--PFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGE 1216 Query: 702 PGSQMPPQPPG 712 PG PP PPG Sbjct: 1217 PGPPGPPGPPG 1227 Score = 79.7 bits (195), Expect = 3e-14 Identities = 200/846 (23%), Positives = 274/846 (32%), Gaps = 115/846 (13%) Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYE 143 G+ G PGP G GQ PG P G + +A PK GEP + Sbjct: 444 GSAGPPGSPGPQ------GSTGPQGIRGQPGDPGVP-----GFKGEAGPK-GEPGPHGIQ 491 Query: 144 HPGLGALGTQ-------QPPVAVPGGGGGPAAVPEFNNYYGS-------AAPASGGPGGR 189 P +G G + P P G G P + GS A GP G Sbjct: 492 GP-IGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGS 550 Query: 190 AGPCFDQH--GGQQSPGMGMMH--SASAAAAGAPGSMDPL----QNSHEGYPNS-QCNHY 240 +GP Q G PG+ + + G G + PL ++ G P S Sbjct: 551 SGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQ 610 Query: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY 300 PG G G G G +G G G GA G + AG G G Sbjct: 611 PGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGP 670 Query: 301 GGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPT 360 G + G+ P G G PG G A G + G+ P G T Sbjct: 671 PGPTGFQGLPGPPGPPGEGGK--PGDQGVPGDPGAVGPLGPRGERGNPGERGEP-GITG- 726 Query: 361 LNQLLTSPSPMMRSYGGSYPEYS-SPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGM--GL 417 L M +G P+ S PS P P Q G G G+ Sbjct: 727 ----LPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGI 782 Query: 418 GKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNP 477 G + GA+ A + A+ P PG GPT +G P ++ P G NP Sbjct: 783 G-EKGAEGTAGNDG---ARGLPGPLGPPGPAGPT--GEKGEPGPRGLVGPP---GSRGNP 833 Query: 478 HSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPP 537 S+ + G GP GP P G++G PG P Q+ + + P Sbjct: 834 GSRGENGPTGAVGFAGPQGPDGQP-GVKGE-PGE------PGQKGDAGSPGPQGLAGSPG 885 Query: 538 QYGQQGVSGYCQ-QGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQ 596 +G GV G +G Q P P+ + P + +EG Sbjct: 886 PHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEG------ 939 Query: 597 PPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSN 656 PP G P + P+ P G D + +G+T +G Sbjct: 940 PPGLRGDPGSH--GRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGM 997 Query: 657 PAQSPFSPHASPHLSSIPG-GPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQS 715 P Q + +PG +P VG P G+ + GP P PGS P PG + Sbjct: 998 PGQ-----RGERGMPGLPGPAGTPGKVG-PTGATGDK-GPPGPVGPPGSNGPVGEPGPEG 1050 Query: 716 ESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGP-SMSPHPSPGGQMHAG----- 769 + + + ER G + +P A Q P + P +PG G Sbjct: 1051 PAGNDGTPGRDGAVGER----GDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSR 1106 Query: 770 --ISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSG----PGPGMGISANNQ 823 I ++ G GPQ G +G++ ++G PGP Sbjct: 1107 GPIGPPGRAGKRGLPGPQ-GPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGS 1165 Query: 824 MHGQGPSQPCGAVPLGRMPSAGMQNRPFP----------GNMSSMTPSSPGMSQQGGPG- 872 GP P G P G + +G + P P G++ P P G PG Sbjct: 1166 AGIPGPFGPRG--PPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGP----PGEPGP 1219 Query: 873 MGPPMP 878 GPP P Sbjct: 1220 PGPPGP 1225 Score = 79.3 bits (194), Expect = 4e-14 Identities = 202/832 (24%), Positives = 263/832 (31%), Gaps = 155/832 (18%) Query: 113 ADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVP-----GGGGGPA 167 ADP PP + P + GG + G G G + P VP G GPA Sbjct: 83 ADPVTPP--------GECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPA 134 Query: 168 AVPEFNNYYGSAAP-ASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAA-----GAPGS 221 P GS P GP GR GP Q G PG+ A G G Sbjct: 135 GPP------GSQGPRGERGPKGRPGPRGPQ-GIDGEPGVPGQPGAPGPPGHPSHPGPDGL 187 Query: 222 MDPLQNSHEGYPN-----SQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGA 276 P G SQ PG P G G G GG+G G G G G Sbjct: 188 SRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGP 247 Query: 277 GAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAA 336 + G G G G+ G SP +G PG G L Sbjct: 248 MGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARG-----FPGAPGLPGLKGHR 302 Query: 337 AGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQ 396 G + G A PT PM P P P Sbjct: 303 GHKGLEGPKGEVGAPGSKGEAGPT--------GPM------------GAMGPLGPRGMPG 342 Query: 397 SQAAAAGAAAGGQQAAAGM----GLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTM 452 + A GQ+ A GM G +G ++ P + + P + G GP Sbjct: 343 ERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQG 402 Query: 453 GRSQGSPMDPMVMK-RPQLYGMGSNPHSQPQQSSP---YPGGSYGPPGPQRYPIGIQGRT 508 R + P P+ P G P ++ SP P GS GPPG G QG T Sbjct: 403 QRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSP----GPQGST 458 Query: 509 -PGAMAGMQYPQQQDSGDATWKETFWLM--PPQYGQQGVSGYCQQGQQPYYSQQPQP--- 562 P + G Q D G +K P +G QG G G++ + P Sbjct: 459 GPQGIRG----QPGDPGVPGFKGEAGPKGEPGPHGIQGPIG--PPGEEGKRGPRGDPGTV 512 Query: 563 -PHLP------------PQAQYLPSQSQQRYQPQQDMSQEGYGTRSQP--PLAPGKPNHE 607 P P P + LP + + S G++ P P PG P Sbjct: 513 GPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGAR 572 Query: 608 DL--NLIQQERPSSLPDLSGSIDDLPTGTEATLS-----SAVSASGSTSSQGDQSNPAQS 660 L N Q L L +D G ++ ++ G S GD P ++ Sbjct: 573 GLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEA 632 Query: 661 PFSPHASPHLSSIPG-----GPSPSPVGSP-VGSNQSRSGPISPASIPGSQMPPQPPGSQ 714 P PG GPS PVG P + + GP P G PP PPG Sbjct: 633 --GNAGVPGQRGAPGKDGEVGPS-GPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGE- 688 Query: 715 SESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGP--SMSPHPSPGGQMHAGISS 772 G + Q P GP +PG + GI+ Sbjct: 689 ----------------------GGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITG 726 Query: 773 FQ-QSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHG-QGPS 830 + +G +GP GP+G+ P SG P +GP G+ + G GP Sbjct: 727 LPGEKGMAGGHGPD----GPKGS----PGPSGTPGD--TGPPGLQGMPGERGIAGTPGPK 776 Query: 831 QPCGAV-PLGRMPSAGMQN-RPFPGNMSSMTPSSPGMSQQGGPG----MGPP 876 G + G +AG R PG + P+ P ++G PG +GPP Sbjct: 777 GDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGP-TGEKGEPGPRGLVGPP 827 Score = 62.4 bits (150), Expect = 5e-09 Identities = 150/622 (24%), Positives = 192/622 (30%), Gaps = 96/622 (15%) Query: 82 LGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGR 141 L G G A GPD + G S G PPG L PG+ A G P G + Sbjct: 727 LPGEKGMAGGHGPDGPK---GSPGPSGTPGDTGPPG--LQGMPGERGIA----GTP-GPK 776 Query: 142 YEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASG----GPGGRAGPCFDQH 197 + G+G G + G G +P G A P GP G GP + Sbjct: 777 GDRGGIGEKGAEGT-----AGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRG 831 Query: 198 G----GQQSPGMGMMHSASAAAAGAPGSM----DPLQNSHEGYPNSQCNHYPGYSRPGAG 249 G+ P + + G PG +P Q G P Q G Sbjct: 832 NPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQ----------GLA 881 Query: 250 GGGGGGGGGG--GGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY 307 G G G G G GG G G GA G A A A G G G G Sbjct: 882 GSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPP 941 Query: 308 GVLSSPRQQGGGMMMGPGG--GGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLL 365 G+ P G GP G GG G P G T Q Sbjct: 942 GLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPG--------PDGPPGPAGTTGQRG 993 Query: 366 TSPSPMMRSYGGSYPEYSSPSAPPP--PPSQPQSQAAAAGAAAGGQQAAAGM-GLGKDMG 422 P G E P P P P + A G G G + G Sbjct: 994 IVGMP------GQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPG 1047 Query: 423 AQYAAASPAWAAAQQRSHPAMSPGTPGPT-MGRSQGSPMDPMVMKRPQLYGMGSNPHSQP 481 + A + G PGP + SQG+P P + P G +P S+ Sbjct: 1048 PEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRG 1107 Query: 482 QQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLM-----P 536 P G G PGPQ P G +G + + D G + L P Sbjct: 1108 PIGPPGRAGKRGLPGPQG-PRGDKG---------DHGDRGDRGQKGHRGFTGLQGLPGPP 1157 Query: 537 PQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQP-----QQDMSQEGY 591 G+QG +G P+ + P P P + P P + EG Sbjct: 1158 GPNGEQGSAGI----PGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGP 1213 Query: 592 GTRSQPPLAPGKPNH------EDLNLIQQERPSSLPDLS---GSIDD---LPTGTEATLS 639 PP PG P H + + + P LP+ + + DD G ATL Sbjct: 1214 PGEPGPPGPPGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDKNKTDPGVHATLK 1273 Query: 640 SAVS-ASGSTSSQGDQSNPAQS 660 S S S G + +PA++ Sbjct: 1274 SLSSQIETMRSPDGSKKHPART 1295 Score = 57.8 bits (138), Expect = 1e-07 Identities = 107/440 (24%), Positives = 124/440 (28%), Gaps = 73/440 (16%) Query: 79 NNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS--------------KP 124 N G G PQ GPD + G + G A PGP L+ K Sbjct: 839 NGPTGAVGFAGPQ-GPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKG 897 Query: 125 GDEDDAPP-KMGEP-AGGRYEHPGLGALGTQQPPVAVPGGGGGPA--AVPEFNNYYGSAA 180 G PP G P + GR PG P+ PG G P P + G Sbjct: 898 GRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRG 957 Query: 181 PAS--GGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCN 238 PA GGPG + P D G P + G PG Q G Sbjct: 958 PAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPG-----QRGERG------- 1005 Query: 239 HYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGG 298 PG P G G G G G G G G+ G A G G Sbjct: 1006 -MPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAV 1064 Query: 299 GYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGAT 358 G G G P QG GP G A G AGQ P Sbjct: 1065 GERGDRGDPGPAGLPGSQGAPGTPGPVG---------APGD--------AGQRGDPG--- 1104 Query: 359 PTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG-GQQAAAGM-G 416 S G P + P P P+ G GQ+ G G Sbjct: 1105 ---------------SRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTG 1149 Query: 417 LGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSN 476 L G A P PG GP+ P+ P + P + G Sbjct: 1150 LQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGP--IGPPGVRGSVGE 1207 Query: 477 PHSQPQQSSPYPGGSYGPPG 496 + P P G GPPG Sbjct: 1208 AGPEGPPGEPGPPGPPGPPG 1227 >gi|55956910 meningioma 1 [Homo sapiens] Length = 1320 Score = 93.2 bits (230), Expect = 3e-18 Identities = 130/486 (26%), Positives = 165/486 (33%), Gaps = 84/486 (17%) Query: 40 HHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSL----------------- 82 H H +LQQQ Q QQQQQQQQQQQQQQQQQQ N +L Sbjct: 514 HPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQP 573 Query: 83 ------------------GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKP 124 GG GG QP + E GG+ + G + P L + Sbjct: 574 NLAQLGHPGDVGQGGLVHGGPVGGLAQPNFERE----GGSTGAGRLGTFEQQAPHLAQES 629 Query: 125 GDEDDAPPKMGEPAGGRYEHPGLGA-LGTQQP---PVAVPGGGG----GPAAVPEFNNYY 176 P G+ R GL A G P P PGG G GP P Sbjct: 630 AWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGE 689 Query: 177 GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQ 236 G PA PG + G G QSPG G + SAA+ P D ++ G P Sbjct: 690 GH-VPALPSPGLQFGGSLGGLGQLQSPGAG-VGLPSAASERRPPPPDFATSALGGQPGFP 747 Query: 237 CNHYPGYSRPGAGGGGGG--GGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGG 294 S P +G G GGGGGS GGGGGGGA +A+ A Sbjct: 748 FGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSL 807 Query: 295 GGGGGYGGSSAGYG----------------VLSSPRQQGGGMMMGPGGGGAASLSKAAAG 338 G +G L +P P G G Sbjct: 808 GSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDG 867 Query: 339 SAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQ 398 +A G G + P G P +P P S G+ S S PP PP+Q Sbjct: 868 AAVAG---NPGSDYFPGGTAP------GAPGPGGPS--GTSSSGSKASGPPNPPAQGDGT 916 Query: 399 AAA------AGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTM 452 + + + + G+ + G G G+ + + + S S G PG + Sbjct: 917 SLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSP 976 Query: 453 GRSQGS 458 G+ Q S Sbjct: 977 GQQQAS 982 Score = 81.6 bits (200), Expect = 8e-15 Identities = 230/994 (23%), Positives = 308/994 (30%), Gaps = 251/994 (25%) Query: 115 PPGP--PLLSKPGDEDDAPPKMG---EPAGGRYE-HPGLGALGTQQPPVAVPGGGGGPAA 168 PPGP P +S G+ PP +G EP G H L A G Q PV Sbjct: 44 PPGPVDPAMSALGE----PPILGMNMEPYGFHARGHSELHAGGLQAQPV----------- 88 Query: 169 VPEFNNYYGSAAPASGGPGG----RAGPCFDQHGGQQSPGMGMMHSAS----AAAAGAPG 220 + ++G P G PG + P F + G PG +H AAG G Sbjct: 89 ----HGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLG 144 Query: 221 SMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGG------------SGGGGGG 268 S P +E SQ G RPG G + Sbjct: 145 SQPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFH 204 Query: 269 GGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSP-------------RQ 315 G + G+ + ++ A G + +G+ + SP RQ Sbjct: 205 GLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQ 264 Query: 316 QGGGMMMG----PGGGGAASLSKAAAGSAAGG-----------------FQRFAGQNQHP 354 GG G P G LSK A F+RF+G + P Sbjct: 265 VPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMP 324 Query: 355 SGATPTLNQ---LLTSPS---PMMRSYGGSYPEYSSPSAPPP--------PPSQPQSQAA 400 G P++ L+ P P + P P PP PP+ P+ Q Sbjct: 325 VGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQG 384 Query: 401 AAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQ---- 456 AG +GG Q M + +Y + S P S P P +Q Sbjct: 385 EAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQH 444 Query: 457 -GSPMDPMVMKRPQLYGMGS------------------NPHSQPQQSSPYPG--GSYGPP 495 +P V KRP+ GS + H P S YPG G + PP Sbjct: 445 FDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSP---SAYPGLPGEFTPP 501 Query: 496 GPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPY 555 P +P G + P P Q QQ QQ Sbjct: 502 VPDSFPSGPPLQHPA-------PDHQS-------------------------LQQQQQQQ 529 Query: 556 YSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDL---NLI 612 QQ Q Q QQ+ Q QQ Q+ + + L NL Sbjct: 530 QQQQQQ-------------QQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLA 576 Query: 613 QQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSS 672 Q P + G + P G A + GST + + Q+P S S Sbjct: 577 QLGHPGDVGQ-GGLVHGGPVGGLAQ-PNFEREGGSTGAGRLGTFEQQAPHLAQESAWFS- 633 Query: 673 IPGGPSPSPVGSPVGSNQSRSG-PISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQE 731 GP P P G + SG P S PP PPG L + P+ QE Sbjct: 634 ---GPHPPP-GDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSG------VLFRGPL-QE 682 Query: 732 RGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGP 791 M G P + PSPG Q + G Sbjct: 683 PMRMPGEGHVPAL---------------PSPGLQFGGSL-------------------GG 708 Query: 792 QGNYSRPPAYSGVPSASYS--GPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNR 849 G P A G+PSA+ P P SA + GQ P P GA AG Q+ Sbjct: 709 LGQLQSPGAGVGLPSAASERRPPPPDFATSA---LGGQ-PGFPFGA--------AGRQST 756 Query: 850 PFPGNMSSMTPSSPGMSQQGGPGMG----PPMPTVNRKAQEAAAAVMQAAANSAQSRQGS 905 P G + PS+ G G G G PP P + +Q +A+ + A + + ++ S Sbjct: 757 PHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDF-QPSQRTSASKLGALSLGSFNKPSS 815 Query: 906 FPGMNQSGLMASSSPYSQPM------NNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMM 959 + +A+ S Q M N + N + PP N + G A Sbjct: 816 KDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETD---GAAVAG 872 Query: 960 SPGESKLPLPLKADGKEEGTPQPESKSKKSSSST 993 +PG P G G P P S SSS + Sbjct: 873 NPGSDYFP-----GGTAPGAPGPGGPSGTSSSGS 901 Score = 66.6 bits (161), Expect = 3e-10 Identities = 119/475 (25%), Positives = 168/475 (35%), Gaps = 65/475 (13%) Query: 83 GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRY 142 GG+ GG Q ++ P G SAA + PP S G + P A GR Sbjct: 703 GGSLGGLGQ----LQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFP----FGAAGRQ 754 Query: 143 EHPGLGALGTQQPPVA-----VPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQH 197 P G G PP A GGGGG A P ++ S ++ G + F++ Sbjct: 755 STPHSGP-GVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKP 813 Query: 198 GGQQSP-GMGMMHSASAA------AAGAP-------------GSMDPLQNSHEGYP---N 234 + + G + + S A + GAP G QN +G N Sbjct: 814 SSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGN 873 Query: 235 SQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGG----GAGAGGAGAGAVAAAAAAAAA 290 +++PG + PGA G GG G GS G G G + + + + Sbjct: 874 PGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGK 933 Query: 291 AAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLS---KAAAGSAAGGFQRF 347 GGGG G G G +S P P GGA +S + A+G+A GG Sbjct: 934 PVSGGGGRGRGRRKRDSGHVS-PGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSS-- 990 Query: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407 AG+ + GA + LTSPS G P +S +++ Sbjct: 991 AGETR---GAPTPHEKALTSPS---WGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEF 1044 Query: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467 + +D + + A A + SP P +G + P P Sbjct: 1045 ASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAP----- 1099 Query: 468 PQLYGMG--SNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQ 520 P G+G SN S P Y GG G PG P Q RTP + +G P + Sbjct: 1100 PPALGLGIMSNSTSTPDS---YGGG--GGPGHPGTPGLEQVRTPTSSSGAPPPDE 1149 Score = 56.2 bits (134), Expect = 3e-07 Identities = 109/462 (23%), Positives = 164/462 (35%), Gaps = 81/462 (17%) Query: 1121 QPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHD 1180 Q P + GS Q G N PG AS HG GG + + Sbjct: 95 QQPHHGHPGSHHPHQHHPHFGGNFGGPDPG-------ASCLHGGRLLGYGGAAGGLGSQP 147 Query: 1181 PFSD----VSDSSFPKRNSMTPNAP------YQQGMS---MPDVMGRMPYEPNKDP-FGG 1226 PF++ +++S P+ S P P + G S +P + PN+ F G Sbjct: 148 PFAEGYEHMAESQGPE--SFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHG 205 Query: 1227 MRKVPGSSEPFMTQGQMPNSSMQDM--YN---QSPSGAMSNLGMGQRQ-QFPYGASYDRR 1280 + GS + ++ N D YN ++PSG + Q P+ A+ Sbjct: 206 LPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAA---- 261 Query: 1281 HEPYGQQYPGQG-PPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYS 1339 G+Q PG P + P GL K H PP ++ + Q Sbjct: 262 ----GRQVPGGAFPGASAMPRAAGMVGLS------KMHAQ----PPQQQPQ----QQQQP 303 Query: 1340 SQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSS 1399 QQQ+ + + +SG + P+ G P SR + P Q PP P Q Sbjct: 304 QQQQQQHGVFFERFSGARKMPV-GLEPSVGSRHPLMQPPQ---QAPPPPQQQPPQQPPQQ 359 Query: 1400 EGPQQNMWAARND-----MPYPYQNRQG-PGGPTQ--APPYPGMNRTDDMMVPDQRINHE 1451 + P R + +P P Q G P G Q P P + + P R+ + Sbjct: 360 QPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEY--PIHRLENR 417 Query: 1452 SQWPSH-----VSQRQPYMSSSASMQPITRPP------QPSYQTPPSLPNHISRAPSPAS 1500 S P + P + + +Q PP +P + P S + + + Sbjct: 418 SMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSM 477 Query: 1501 FQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPP 1542 +L+N +SPS P LP + P VP S +GPP Q P Sbjct: 478 HNGALDNHLSPSAYPGLPG----EFTPPVPDSFPSGPPLQHP 515 Score = 52.8 bits (125), Expect = 4e-06 Identities = 207/923 (22%), Positives = 264/923 (28%), Gaps = 200/923 (21%) Query: 46 HALQQQLNQFQQQQQQQQQQQQQQQQQQHP---ISNNNSL------------GGAGGGAP 90 H L Q Q QQQ QQ QQQ P + NS G GG Sbjct: 335 HPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQ 394 Query: 91 QPGP-------DMEQPQHGGAKDSA------AGGQADPPGPPLLSKPGDEDDAPPKMGEP 137 GP E P H S PP ++ DAPP M Sbjct: 395 DGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVA 454 Query: 138 AGGRYEHPGL---------------GALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPA 182 R++ PG GAL P A PG G P + + S P Sbjct: 455 KRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPG--EFTPPVPDSFPSGPPL 512 Query: 183 SG-GPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCN-HY 240 P ++ Q QQ L N Q Sbjct: 513 QHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQ 572 Query: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGG-------GGGAGAGGAGAGAVAAAAAAAAAAAG 293 P ++ G G G GG GG GG GG GAG G A A +A Sbjct: 573 PNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESA-- 630 Query: 294 GGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQH 353 + G G L R G G+ P G S A G F G Q Sbjct: 631 -----WFSGPHPPPGDLLPRRMGGSGL---PADCGPHDPSLAPPPPPGGSGVLFRGPLQE 682 Query: 354 PSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAA 413 P P + PSP ++ +GGS G Q A Sbjct: 683 PM-RMPGEGHVPALPSPGLQ-FGGSL-----------------------GGLGQLQSPGA 717 Query: 414 GMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGM 473 G+GL AA+++R P P +G G P G Sbjct: 718 GVGLPS-------------AASERRPPP---PDFATSALGGQPGFPFGAA--------GR 753 Query: 474 GSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFW 533 S PHS P +SP G G G + G G YP Q D Sbjct: 754 QSTPHSGPGVNSPPSAGGGG------------GSSGGGGGGGAYPPQPD----------- 790 Query: 534 LMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQA--QYLPSQSQQRYQPQQDMSQEGY 591 P Q G G +++ +L Q+ L + Q + Sbjct: 791 FQPSQRTSASKLGALSLGS---FNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVT 847 Query: 592 GTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQ 651 + PP K L Q E + + D P GT SG++SS Sbjct: 848 FNKKNPPEGKRK-------LSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSG 900 Query: 652 GDQSNPAQSP-------FSPHAS-PHLSSIPGGPSPSPVGSPVGSNQSRSGPISP----- 698 S P P SP+ + S G P G G + SG +SP Sbjct: 901 SKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFD 960 Query: 699 ---ASIPGSQMPPQPPGSQSES------SSHPALSQSPMPQERGFMAGTQRNPQMAQYGP 749 A+ P PG Q S SS +P P E+ + + G Sbjct: 961 KYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD 1020 Query: 750 QQT------GPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQ----MSQYGPQG--NYSR 797 Q G + S SP + F S +Y + S PQ SR Sbjct: 1021 QPDLIGSLDGGAKSDSSSPN------VGEFASDEVSTSYANEDEVSSSSDNPQALVKASR 1074 Query: 798 PPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSS 857 P +G P G G G GP P A+ LG M ++ + G Sbjct: 1075 SPLVTGSPKLPPRGVGAGE----------HGPKAPPPALGLGIMSNSTSTPDSYGGGGGP 1124 Query: 858 MTPSSPGMSQQGGP--GMGPPMP 878 P +PG+ Q P G P P Sbjct: 1125 GHPGTPGLEQVRTPTSSSGAPPP 1147 Score = 45.1 bits (105), Expect = 8e-04 Identities = 165/788 (20%), Positives = 257/788 (32%), Gaps = 201/788 (25%) Query: 592 GTRSQPPLAPGKPNHEDLNLIQQ---ERPSSLPDLSGS-------------IDDLPTGTE 635 G SQPP A G + + + +RP +LPD S +D P Sbjct: 142 GLGSQPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRA- 200 Query: 636 ATLSSAVSASGSTS---------SQG-----DQSNPAQSP------FSPHAS----PHLS 671 A+ S+SGS S +QG + + P ++P FSP S PH + Sbjct: 201 ASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYA 260 Query: 672 S---IPGGPSPSPVGSP-----VGSNQSRSGPISPASIPGSQMPPQPPGSQ--------S 715 + +PGG P P VG ++ + P P P Q PQ Q S Sbjct: 261 AGRQVPGGAFPGASAMPRAAGMVGLSKMHAQP--PQQQPQQQQQPQQQQQQHGVFFERFS 318 Query: 716 ESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQ 775 + P + + M Q+ P Q P Q P P P P G+ Q Sbjct: 319 GARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPP------GLLVRQN 372 Query: 776 SNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGA 835 S PQ + +G PS GP + PSQ Sbjct: 373 SCPPALPRPQQGE-------------AGTPSGGLQDGGPML------------PSQHAQF 407 Query: 836 VPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAA 895 P ++NR SM P S + P PP N++ Q A Sbjct: 408 ----EYPIHRLENR-------SMHPYSEPVFSMQHP---PPQQAPNQRLQHFDAPPYM-- 451 Query: 896 ANSAQSRQGSFPGMNQSGLMAS--SSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASV 953 N A+ + FPG AS S ++ ++N S P P + +S + Sbjct: 452 -NVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGP 510 Query: 954 GLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKL 1013 L +P L + +++ Q + + ++ + ++ + +++ Sbjct: 511 PLQHP-APDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQR 569 Query: 1014 WVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNV 1073 L + G VG+ L V +GGLAQ N ++ + Sbjct: 570 LRQPNLAQLGHPGD-------VGQGGL------VHGGPVGGLAQPNFEREGGSTGAG-RL 615 Query: 1074 GTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQG 1133 GT A L ++ + G PPP G Sbjct: 616 GTFEQQAPHLAQESAWF---------SGPHPPP--------------------------G 640 Query: 1134 PQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKR 1193 P+ G + + P D P P+ P P GG Sbjct: 641 DLLPRRMGGSGL---PADCGPHDPSLAP----PPPPGG---------------------- 671 Query: 1194 NSMTPNAPYQQGMSMPDVMGRMPYEPNKD-PFGGMRKVPGSSEPFMTQGQMPNSSMQDMY 1252 + + P Q+ M MP G +P P+ FGG G + +P+++ + Sbjct: 672 SGVLFRGPLQEPMRMPGE-GHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASE--- 727 Query: 1253 NQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPG-QGPPS----GQPPYGGHQPGL 1307 + P + +G + FP+GA+ R+ P+ PG PPS G GG G Sbjct: 728 RRPPPPDFATSALGGQPGFPFGAA-GRQSTPHSG--PGVNSPPSAGGGGGSSGGGGGGGA 784 Query: 1308 YPQQPNYK 1315 YP QP+++ Sbjct: 785 YPPQPDFQ 792 Score = 41.6 bits (96), Expect = 0.009 Identities = 33/102 (32%), Positives = 40/102 (39%), Gaps = 14/102 (13%) Query: 58 QQQQQQQQQQQQQQQQHPISNNNSLG----------GAGGGAPQPGPDMEQPQHGGAKDS 107 QQQ QQQQQ QQQQQQH + G G P P + P + Sbjct: 294 QQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPP 353 Query: 108 AAGGQADPPGPP-LLSKPGDEDDAPPKMGEPAGGRYEHPGLG 148 Q PP PP LL + ++ PP + P G P G Sbjct: 354 QQPPQQQPPPPPGLLVR---QNSCPPALPRPQQGEAGTPSGG 392 Score = 33.1 bits (74), Expect = 3.1 Identities = 81/347 (23%), Positives = 117/347 (33%), Gaps = 83/347 (23%) Query: 1259 AMSNLG----MGQRQQFPYG---ASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQ 1311 AMS LG +G + PYG + H Q P G GQ P+ GH +P Q Sbjct: 51 AMSALGEPPILGMNME-PYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHPHQ 109 Query: 1312 PNYKRHMDGMYGPP----AKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRP------- 1360 + H G +G P + H G + YGG+ G +P Sbjct: 110 --HHPHFGGNFGGPDPGASCLHGGRLLG-------------YGGAAGGLGSQPPFAEGYE 154 Query: 1361 --IQGQYPYPYSRERMQGPGQI--------QTHGIPPQMM---GGPLQSSSSEGPQQNMW 1407 + Q P + +R PG + +H +P + P +++S G + Sbjct: 155 HMAESQGPESFGPQR---PGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSG 211 Query: 1408 AARNDMPYPYQNRQGPGGPTQAPPYPGMNRTD--DMMVPDQRINHESQWPSHVSQRQ--- 1462 + + + QG + YPG + DM P + E Q P + + RQ Sbjct: 212 SDSHSLEPRRVTNQGAVDSLEY-NYPGEAPSGHFDMFSPS---DSEGQLPHYAAGRQVPG 267 Query: 1463 ------PYMSSSASM--------QPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENR 1508 M +A M QP + PQ Q H S R + Sbjct: 268 GAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQH-GVFFERFSGARKMPVG 326 Query: 1509 MSPSKSPFLPSMKMQKVMPTVPTSQVTGPPP--QPPPIRREITFPPG 1553 + PS P M+ + P P Q PP QPPP PPG Sbjct: 327 LEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPP-------PPG 366 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 91.7 bits (226), Expect = 7e-18 Identities = 211/866 (24%), Positives = 276/866 (31%), Gaps = 145/866 (16%) Query: 82 LGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDE-------------D 128 L G G PGP H D + PPGPP PGD+ D Sbjct: 424 LDGQPGAPGLPGPPGPAGPHIPPSDEIC--EPGPPGPP--GSPGDKGLQGEQGVKGDKGD 479 Query: 129 DAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPG--------GGGGPAAVPEFNNYYGSAA 180 +G G PGL L + PG G GP +P G A Sbjct: 480 TCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPG--A 537 Query: 181 PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMD-PLQNSHEGYPNSQCNH 239 P G G G G + G S A G PG P Q+ G P + Sbjct: 538 PGFPGSKGEPGDILTFPGMKGDKG----ELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEP 593 Query: 240 ----YPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGG 295 + G P G G G G G G G G G VA G Sbjct: 594 GGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKG 653 Query: 296 GGG------------GYGGSSAGYGVLSSPRQQGGGMMMG-PGGGGAASLSKAAAGSAAG 342 G G G G+ P G + G PG G + G Sbjct: 654 DPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPG 713 Query: 343 --GFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGG--SYPEYSSPSAPPPPPSQPQSQ 398 GF G P GA T ++ P + G P ++ P PP PP P + Sbjct: 714 PKGFPGIPG----PPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPG-PPGPPGLPGFK 768 Query: 399 AAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGS 458 A G G G+ G + P PG PG + G Sbjct: 769 GALGPKGDRGFPGPPGPP-GRT-GLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGP 826 Query: 459 PMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSY--GPPGPQRYPIGIQGRTPGAMAGMQ 516 P P + +P L+G+ ++ P P G GPPG + P GI G PG + Sbjct: 827 PGIPGPIGQPGLHGIPG------EKGDPGPPGLDVPGPPGERGSP-GIPG-APGPIGPPG 878 Query: 517 YPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQY--LPS 574 P A+ P G+ G+ G P P +P ++ L Sbjct: 879 SPGLPGKAGASG------FPGTKGEMGMMGP---------PGPPGPLGIPGRSGVPGLKG 923 Query: 575 QSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGT 634 + QP G++ +P L PG P D NL+ + P L G Sbjct: 924 DDGLQGQPGLPGPTGEKGSKGEPGL-PGPPGPMDPNLLGSKGEKGEPGLPG--------- 973 Query: 635 EATLSSAVSASGSTSSQGDQSNPAQS-------PFSPHASPHLSSIPGGPSPSPVGSPVG 687 + G GD P S P P +P L PG P + +G Sbjct: 974 ---IPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIG 1030 Query: 688 SN-----QSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNP 742 Q GP P+ +PG P PG + + P +S +P + G + P Sbjct: 1031 DMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGD-PGISSIGLPG----LPGPKGEP 1085 Query: 743 QMAQYGPQQTG-------PSMSPHP-SPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGN 794 + Y P G P + P +PG + G+ F GT GP GP+G Sbjct: 1086 GLPGY-PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP-----GTPGPP----GPKG- 1134 Query: 795 YSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPS-AGMQNRPF-P 852 S PP G+P PGP G Q GP G +P AG + P P Sbjct: 1135 ISGPPGNPGLPGE----PGPVGGGGHPGQ---PGPPGEKGKPGQDGIPGPAGQKGEPGQP 1187 Query: 853 GNMSSMTPSSPGMSQQGGPGMGPPMP 878 G + P PG+S Q G G P +P Sbjct: 1188 GFGNPGPPGLPGLSGQKGDGGLPGIP 1213 Score = 91.3 bits (225), Expect = 1e-17 Identities = 197/793 (24%), Positives = 241/793 (30%), Gaps = 166/793 (20%) Query: 92 PGPDMEQPQHGGAKDSAAGGQADPPGPP----LLSKPGDEDDAPPKMGEPAGGRYEHPGL 147 PGP G G PPGPP L PG + D P G+P G PGL Sbjct: 759 PGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN-GQP--GPMGPPGL 815 Query: 148 GALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGM 207 +G Q PP P G GP P + G G PG G + SPG+ Sbjct: 816 PGIGVQGPPG--PPGIPGPIGQPGLHGIPGE----KGDPGPPGLDVPGPPGERGSPGI-- 867 Query: 208 MHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGG--GGSGGG 265 GAPG + P P S PG PG G G G G G G Sbjct: 868 --------PGAPGPIGP--------PGS-----PGL--PGKAGASGFPGTKGEMGMMGPP 904 Query: 266 GGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPG 325 G G G G G G G GS G+ P ++ G Sbjct: 905 GPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKG 964 Query: 326 GGGAASLSKAAAGSAAGGFQRFAGQNQHPS-GATPTL--------------NQLLTSPSP 370 G L S G+Q G P P L L P Sbjct: 965 EKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG 1024 Query: 371 MMRSYGG-SYPEYSSPSAPPPP---PSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYA 426 + + G +P PP P P QP S G + +GL G + Sbjct: 1025 LKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGE 1084 Query: 427 AASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSP 486 P + PG PG +GS DP L G+ P ++ Q P Sbjct: 1085 PGLPGY------------PGNPG-----IKGSVGDP------GLPGLPGTPGAKGQPGLP 1121 Query: 487 YPGGSYGPPGPQRY--PIGIQG--RTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQ 542 G+ GPPGP+ P G G PG + G +P Q K P Q G Sbjct: 1122 GFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGK------PGQDGIP 1175 Query: 543 GVSGYCQQGQQPYYSQQPQPPHLP--------------PQAQYLPSQSQQRYQPQQDMSQ 588 G +G + QP + P PP LP P LP P+ + Sbjct: 1176 GPAGQKGEPGQPGFG-NPGPPGLPGLSGQKGDGGLPGIPGNPGLPG-------PKGEPGF 1227 Query: 589 EGYGTRSQPPLAPGKPNHE---------------DLNLIQQERPSSLPDLSGSIDDLPTG 633 G+ PP PG P L E P LP G + Sbjct: 1228 HGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNP 1287 Query: 634 TEATLSSAVSASGSTSSQGDQSNPAQSPFS-PHASPHLSSIPGGPS-PSPVGSPVGSNQS 691 + L G G Q NP + + P L +PG P P G P Sbjct: 1288 GQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVP------ 1341 Query: 692 RSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQ 751 G P PG PP PPG S + P G + P GPQ Sbjct: 1342 --GSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLP-----GPQ- 1393 Query: 752 TGPSMSPHPS--PGGQMHAGISSFQ-------------QSNSSGTYGPQMSQYGPQGNYS 796 GP P P+ PG G+ F Q + G GP GP G Sbjct: 1394 -GPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPP----GPDG-LQ 1447 Query: 797 RPPAYSGVPSASY 809 PP G S ++ Sbjct: 1448 GPPGPPGTSSVAH 1460 Score = 73.2 bits (178), Expect = 3e-12 Identities = 212/887 (23%), Positives = 263/887 (29%), Gaps = 186/887 (20%) Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPP----LLSKPGD--EDDAPPKMGEP 137 GA G PG + + + G G PPGPP + +PG P G P Sbjct: 114 GAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNP 173 Query: 138 AGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQH 197 +PG + P +PG G P G P GP G GP + Sbjct: 174 G-----YPGPPGIQGLPGPTGIPGPIGPPGPP-------GLMGPP--GPPGLPGPKGNMG 219 Query: 198 GGQQSPGMGMMHSASAAAAGAPGSMDP--------LQNSHEGYPNSQCNHYPGYSRPGAG 249 Q P G PG + Q +G P + P PG Sbjct: 220 LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP----PGIR 275 Query: 250 GGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGV 309 G G GG G G G G G G G G G G G Sbjct: 276 GPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGD 335 Query: 310 LSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPS 369 P G +++ G G K G G G+ P P Sbjct: 336 TGPPGPPG--LVIPRPGTGITIGEKGNIGLP--GLPGEKGERGFPGIQGPP--------- 382 Query: 370 PMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAAS 429 G P ++ PP PP P + G GL GA Sbjct: 383 ------GLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGP 436 Query: 430 PAWAAAQ-QRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYG---------MGSNPHS 479 P A S PG PGP GSP D + + G +G+ Sbjct: 437 PGPAGPHIPPSDEICEPGPPGPP-----GSPGDKGLQGEQGVKGDKGDTCFNCIGTGISG 491 Query: 480 QPQQSS----PYPGGSYGPPGPQRY--------PIGIQGRTPGAMAGMQYPQQQ-DSGDA 526 P Q P P GS G PG + P G+ G PGA +P + + GD Sbjct: 492 PPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPG-IPGAPGAPGFPGSKGEPGDI 550 Query: 527 TWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLP--PQAQYLPSQSQQRYQPQQ 584 TF M G+ G G P P LP P LP + +P Sbjct: 551 L---TFPGMKGDKGELGSPG------------APGLPGLPGTPGQDGLPGLPGPKGEPGG 595 Query: 585 DMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDL---------PTGTE 635 + G PP PG LP L G+I + P G E Sbjct: 596 ITFKGERG----PPGNPG-----------------LPGLPGNIGPMGPPGFGPPGPVG-E 633 Query: 636 ATLSSAVSASGSTSSQGDQSNPAQSPFSPH-----------------ASPHLSSIPGGPS 678 + G G + +P Q+ P P L PG P Sbjct: 634 KGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPG 693 Query: 679 -PSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSE--SSSHPALSQSPMPQ-ERGF 734 P G P GP P PG PP PG+ P P P+ E GF Sbjct: 694 IPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF 753 Query: 735 -MAGTQRNPQMAQY----GPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQY 789 + G P + + GP+ G P P PG G+ G GP Q Sbjct: 754 ALPGPPGPPGLPGFKGALGPK--GDRGFPGP-PGPPGRTGLDGL--PGPKGDVGPN-GQP 807 Query: 790 GPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHG----QGPSQPCG---AVPLGRMP 842 GP G PP G+ GP G +HG +G P G P G Sbjct: 808 GPMG----PPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERG 863 Query: 843 SAGMQNRPFPGNMSSMTPSSPGMSQQGG----PG-------MGPPMP 878 S G+ P P P SPG+ + G PG MGPP P Sbjct: 864 SPGIPGAPGPIG----PPGSPGLPGKAGASGFPGTKGEMGMMGPPGP 906 Score = 63.2 bits (152), Expect = 3e-09 Identities = 106/421 (25%), Positives = 121/421 (28%), Gaps = 127/421 (30%) Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYE 143 G GG QPGP E+ + G GQ PG P PG Sbjct: 1152 GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGP----------------- 1194 Query: 144 HPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSP 203 PGL L Q+ +PG G P G PG + P F G Q P Sbjct: 1195 -PGLPGLSGQKGDGGLPGIPGNP-----------------GLPGPKGEPGFHGFPGVQGP 1236 Query: 204 GMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGG--GGGGG 261 G PGS P +G P Q PG RPG G G G G GG Sbjct: 1237 ------------PGPPGSPGPALEGPKGNPGPQ--GPPG--RPGLPGPEGPPGLPGNGGI 1280 Query: 262 SGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQG-GGM 320 G G G G G G G G+ +P + G GM Sbjct: 1281 KGEKGNPGQPGLPGL---------------------PGLKGDQGPPGLQGNPGRPGLNGM 1319 Query: 321 MMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYP 380 PG G GF G + P A P P Sbjct: 1320 KGDPGLPGVP------------GFPGMKGPSGVPGSAGPE-----------------GEP 1350 Query: 381 EYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSH 440 P PP P P Q+ AG GL G Q P Sbjct: 1351 GLIGPPGPPGLPG-PSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPG--------- 1400 Query: 441 PAMSPGTPG----PTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPG 496 P PG PG P + G DP G+ P ++ P P G GPPG Sbjct: 1401 PTGPPGDPGRNGLPGFDGAGGRKGDP---------GLPGQPGTRGLDGPPGPDGLQGPPG 1451 Query: 497 P 497 P Sbjct: 1452 P 1452 Score = 54.3 bits (129), Expect = 1e-06 Identities = 165/699 (23%), Positives = 217/699 (31%), Gaps = 154/699 (22%) Query: 230 EGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAA 289 EG+P PG+ P G G G G G G G G G Sbjct: 56 EGHPG-----LPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMP 110 Query: 290 AAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAG 349 G G G G + G P G + GP G K GS G Sbjct: 111 GHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSII--MSSLPG 168 Query: 350 QNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQ 409 +P P Q L P+ + G P PP PP P G Sbjct: 169 PKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPP--GLMGPPGPPGLP------------GP 214 Query: 410 QAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQ 469 + G+ G + Q P PG PG Q P+D K Q Sbjct: 215 KGNMGLNFQGPKGEK---------GEQGLQGP---PGPPGQIS--EQKRPIDVEFQKGDQ 260 Query: 470 LYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWK 529 G+ + + P P G GPPGP PG G + Q + Sbjct: 261 --GLPGD------RGPPGPPGIRGPPGP-----------PGGEKGEKGEQGE-------- 293 Query: 530 ETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQE 589 P + G+ G G + QP P LP Y P + P +D ++ Sbjct: 294 ------PGKRGKPGKDGE---------NGQPGIPGLPGDPGY-PGE------PGRD-GEK 330 Query: 590 GYGTRSQPPLAPGK--PNHEDLNLIQQERPSSLPDLSGSIDDL-------PTGTEATLSS 640 G + PP PG P I ++ LP L G + P G + Sbjct: 331 GQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGA 390 Query: 641 AVSAS-------GSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPS-PSPVGSPVGSNQSR 692 AV G +GD+ P S P P L PG P P P G P G + Sbjct: 391 AVMGPPGPPGFPGERGQKGDEGPPGISIPGP---PGLDGQPGAPGLPGPPG-PAGPHIPP 446 Query: 693 SGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQT 752 S I PG PP PPGS + + E+G + G + + G + Sbjct: 447 SDEICE---PG---PPGPPGSPGDKG---------LQGEQG-VKGDKGDTCFNCIGTGIS 490 Query: 753 GPSMSPH----PSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSAS 808 GP P P P G + ++ + T GP+G P A G P Sbjct: 491 GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGAT--------GPKGLPGIPGA-PGAPGFP 541 Query: 809 YSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSA----GMQNRPFP-GNMSSMT---- 859 S PG ++ +G GA L +P G+ P P G +T Sbjct: 542 GSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGE 601 Query: 860 ---PSSPGM-------SQQGGPGMGPPMPTVNRKAQEAA 888 P +PG+ G PG GPP P + Q A Sbjct: 602 RGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVA 640 Score = 46.2 bits (108), Expect = 4e-04 Identities = 63/230 (27%), Positives = 70/230 (30%), Gaps = 38/230 (16%) Query: 79 NNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDE----------- 127 + L G G PGP E HG G PGP L G+ Sbjct: 1206 DGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGL 1265 Query: 128 --DDAPPKMGEPAG--------GRYEHPGLGALGTQQPPVAVPGGGGGPA---------- 167 + PP + G G+ PGL L Q P + G G P Sbjct: 1266 PGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGL 1325 Query: 168 -AVPEFNNYYG-SAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPL 225 VP F G S P S GP G G G PG AG PG P Sbjct: 1326 PGVPGFPGMKGPSGVPGSAGPEGEPG-LIGPPGPPGLPGPSGQSIIIKGDAGPPGI--PG 1382 Query: 226 QNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGG 275 Q +G P Q G P G G G G G GG G G G Sbjct: 1383 QPGLKGLPGPQGPQ--GLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPG 1430 Score = 40.4 bits (93), Expect = 0.019 Identities = 69/295 (23%), Positives = 92/295 (31%), Gaps = 36/295 (12%) Query: 633 GTEATLSSAVSASGSTSSQGDQSNPA-------QSPFSPHASPHLSSIPGGPSPSPVGSP 685 G++ S G G + +P + P P IPG P P + P Sbjct: 35 GSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGP 94 Query: 686 VGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGF--MAGTQRNPQ 743 G P +PG PG Q + + P GF + G P Sbjct: 95 PGLPGFPGTP----GLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPG 150 Query: 744 MAQYGPQQTGPSMSPHPSP-GGQMHAGISSFQ-QSNSSGTYGPQMSQYGPQGNYSRPPAY 801 + + MS P P G + G Q +G GP GP G PP Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGP----IGPPG----PPGL 202 Query: 802 SGVPSASYSGPGPGM-GISANNQMHGQGPSQPCGAV----PLGRMPSAGMQNRPFPGNMS 856 G P GP PG+ G N ++ QGP G P G Q RP Sbjct: 203 MGPP-----GP-PGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQ 256 Query: 857 SMTPSSPG-MSQQGGPGM-GPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGM 909 PG G PG+ GPP P K ++ + + PG+ Sbjct: 257 KGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGI 311 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 91.7 bits (226), Expect = 7e-18 Identities = 211/866 (24%), Positives = 276/866 (31%), Gaps = 145/866 (16%) Query: 82 LGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDE-------------D 128 L G G PGP H D + PPGPP PGD+ D Sbjct: 424 LDGQPGAPGLPGPPGPAGPHIPPSDEIC--EPGPPGPP--GSPGDKGLQGEQGVKGDKGD 479 Query: 129 DAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPG--------GGGGPAAVPEFNNYYGSAA 180 +G G PGL L + PG G GP +P G A Sbjct: 480 TCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPG--A 537 Query: 181 PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMD-PLQNSHEGYPNSQCNH 239 P G G G G + G S A G PG P Q+ G P + Sbjct: 538 PGFPGSKGEPGDILTFPGMKGDKG----ELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEP 593 Query: 240 ----YPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGG 295 + G P G G G G G G G G G VA G Sbjct: 594 GGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKG 653 Query: 296 GGG------------GYGGSSAGYGVLSSPRQQGGGMMMG-PGGGGAASLSKAAAGSAAG 342 G G G G+ P G + G PG G + G Sbjct: 654 DPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPG 713 Query: 343 --GFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGG--SYPEYSSPSAPPPPPSQPQSQ 398 GF G P GA T ++ P + G P ++ P PP PP P + Sbjct: 714 PKGFPGIPG----PPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPG-PPGPPGLPGFK 768 Query: 399 AAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGS 458 A G G G+ G + P PG PG + G Sbjct: 769 GALGPKGDRGFPGPPGPP-GRT-GLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGP 826 Query: 459 PMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSY--GPPGPQRYPIGIQGRTPGAMAGMQ 516 P P + +P L+G+ ++ P P G GPPG + P GI G PG + Sbjct: 827 PGIPGPIGQPGLHGIPG------EKGDPGPPGLDVPGPPGERGSP-GIPG-APGPIGPPG 878 Query: 517 YPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQY--LPS 574 P A+ P G+ G+ G P P +P ++ L Sbjct: 879 SPGLPGKAGASG------FPGTKGEMGMMGP---------PGPPGPLGIPGRSGVPGLKG 923 Query: 575 QSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGT 634 + QP G++ +P L PG P D NL+ + P L G Sbjct: 924 DDGLQGQPGLPGPTGEKGSKGEPGL-PGPPGPMDPNLLGSKGEKGEPGLPG--------- 973 Query: 635 EATLSSAVSASGSTSSQGDQSNPAQS-------PFSPHASPHLSSIPGGPSPSPVGSPVG 687 + G GD P S P P +P L PG P + +G Sbjct: 974 ---IPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIG 1030 Query: 688 SN-----QSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNP 742 Q GP P+ +PG P PG + + P +S +P + G + P Sbjct: 1031 DMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGD-PGISSIGLPG----LPGPKGEP 1085 Query: 743 QMAQYGPQQTG-------PSMSPHP-SPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGN 794 + Y P G P + P +PG + G+ F GT GP GP+G Sbjct: 1086 GLPGY-PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP-----GTPGPP----GPKG- 1134 Query: 795 YSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPS-AGMQNRPF-P 852 S PP G+P PGP G Q GP G +P AG + P P Sbjct: 1135 ISGPPGNPGLPGE----PGPVGGGGHPGQ---PGPPGEKGKPGQDGIPGPAGQKGEPGQP 1187 Query: 853 GNMSSMTPSSPGMSQQGGPGMGPPMP 878 G + P PG+S Q G G P +P Sbjct: 1188 GFGNPGPPGLPGLSGQKGDGGLPGIP 1213 Score = 90.9 bits (224), Expect = 1e-17 Identities = 196/791 (24%), Positives = 242/791 (30%), Gaps = 159/791 (20%) Query: 92 PGPDMEQPQHGGAKDSAAGGQADPPGPP----LLSKPGDEDDAPPKMGEPAGGRYEHPGL 147 PGP G G PPGPP L PG + D P G+P G PGL Sbjct: 759 PGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN-GQP--GPMGPPGL 815 Query: 148 GALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGM 207 +G Q PP P G GP P + G G PG G + SPG+ Sbjct: 816 PGIGVQGPPG--PPGIPGPIGQPGLHGIPGE----KGDPGPPGLDVPGPPGERGSPGI-- 867 Query: 208 MHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGG--GGSGGG 265 GAPG + P P S PG PG G G G G G G Sbjct: 868 --------PGAPGPIGP--------PGS-----PGL--PGKAGASGFPGTKGEMGMMGPP 904 Query: 266 GGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPG 325 G G G G G G G GS G+ P ++ G Sbjct: 905 GPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKG 964 Query: 326 GGGAASLSKAAAGSAAGGFQRFAGQNQHPS-GATPTL--------------NQLLTSPSP 370 G L S G+Q G P P L L P Sbjct: 965 EKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG 1024 Query: 371 MMRSYGG-SYPEYSSPSAPPPP---PSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYA 426 + + G +P PP P P QP S G + +GL G + Sbjct: 1025 LKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGE 1084 Query: 427 AASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSP 486 P + PG PG +GS DP L G+ P ++ Q P Sbjct: 1085 PGLPGY------------PGNPG-----IKGSVGDP------GLPGLPGTPGAKGQPGLP 1121 Query: 487 YPGGSYGPPGPQRY--PIGIQG--RTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQ 542 G+ GPPGP+ P G G PG + G +P Q K P Q G Sbjct: 1122 GFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGK------PGQDGIP 1175 Query: 543 GVSGYCQQGQQPYYSQQPQPPHLP-----------PQAQYLPSQSQQRYQP--------- 582 G +G + QP + P PP LP P P + +P Sbjct: 1176 GPAGQKGEPGQPGFG-NPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQ 1234 Query: 583 -------QQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTE 635 + EG P PG+P + L E P LP G + + Sbjct: 1235 GPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQ--GLPGPEGPPGLPGNGGIKGEKGNPGQ 1292 Query: 636 ATLSSAVSASGSTSSQGDQSNPAQSPFS-PHASPHLSSIPGGPS-PSPVGSPVGSNQSRS 693 L G G Q NP + + P L +PG P P G P Sbjct: 1293 PGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVP-------- 1344 Query: 694 GPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTG 753 G P PG PP PPG S + P G + P GPQ G Sbjct: 1345 GSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLP-----GPQ--G 1397 Query: 754 PSMSPHPS--PGGQMHAGISSFQ-------------QSNSSGTYGPQMSQYGPQGNYSRP 798 P P P+ PG G+ F Q + G GP GP G P Sbjct: 1398 PQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPP----GPDG-LQGP 1452 Query: 799 PAYSGVPSASY 809 P G S ++ Sbjct: 1453 PGPPGTSSVAH 1463 Score = 73.2 bits (178), Expect = 3e-12 Identities = 212/887 (23%), Positives = 263/887 (29%), Gaps = 186/887 (20%) Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPP----LLSKPGD--EDDAPPKMGEP 137 GA G PG + + + G G PPGPP + +PG P G P Sbjct: 114 GAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNP 173 Query: 138 AGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQH 197 +PG + P +PG G P G P GP G GP + Sbjct: 174 G-----YPGPPGIQGLPGPTGIPGPIGPPGPP-------GLMGPP--GPPGLPGPKGNMG 219 Query: 198 GGQQSPGMGMMHSASAAAAGAPGSMDP--------LQNSHEGYPNSQCNHYPGYSRPGAG 249 Q P G PG + Q +G P + P PG Sbjct: 220 LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP----PGIR 275 Query: 250 GGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGV 309 G G GG G G G G G G G G G G G Sbjct: 276 GPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGD 335 Query: 310 LSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPS 369 P G +++ G G K G G G+ P P Sbjct: 336 TGPPGPPG--LVIPRPGTGITIGEKGNIGLP--GLPGEKGERGFPGIQGPP--------- 382 Query: 370 PMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAAS 429 G P ++ PP PP P + G GL GA Sbjct: 383 ------GLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGP 436 Query: 430 PAWAAAQ-QRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYG---------MGSNPHS 479 P A S PG PGP GSP D + + G +G+ Sbjct: 437 PGPAGPHIPPSDEICEPGPPGPP-----GSPGDKGLQGEQGVKGDKGDTCFNCIGTGISG 491 Query: 480 QPQQSS----PYPGGSYGPPGPQRY--------PIGIQGRTPGAMAGMQYPQQQ-DSGDA 526 P Q P P GS G PG + P G+ G PGA +P + + GD Sbjct: 492 PPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPG-IPGAPGAPGFPGSKGEPGDI 550 Query: 527 TWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLP--PQAQYLPSQSQQRYQPQQ 584 TF M G+ G G P P LP P LP + +P Sbjct: 551 L---TFPGMKGDKGELGSPG------------APGLPGLPGTPGQDGLPGLPGPKGEPGG 595 Query: 585 DMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDL---------PTGTE 635 + G PP PG LP L G+I + P G E Sbjct: 596 ITFKGERG----PPGNPG-----------------LPGLPGNIGPMGPPGFGPPGPVG-E 633 Query: 636 ATLSSAVSASGSTSSQGDQSNPAQSPFSPH-----------------ASPHLSSIPGGPS 678 + G G + +P Q+ P P L PG P Sbjct: 634 KGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPG 693 Query: 679 -PSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSE--SSSHPALSQSPMPQ-ERGF 734 P G P GP P PG PP PG+ P P P+ E GF Sbjct: 694 IPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF 753 Query: 735 -MAGTQRNPQMAQY----GPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQY 789 + G P + + GP+ G P P PG G+ G GP Q Sbjct: 754 ALPGPPGPPGLPGFKGALGPK--GDRGFPGP-PGPPGRTGLDGL--PGPKGDVGPN-GQP 807 Query: 790 GPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHG----QGPSQPCG---AVPLGRMP 842 GP G PP G+ GP G +HG +G P G P G Sbjct: 808 GPMG----PPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERG 863 Query: 843 SAGMQNRPFPGNMSSMTPSSPGMSQQGG----PG-------MGPPMP 878 S G+ P P P SPG+ + G PG MGPP P Sbjct: 864 SPGIPGAPGPIG----PPGSPGLPGKAGASGFPGTKGEMGMMGPPGP 906 Score = 61.2 bits (147), Expect = 1e-08 Identities = 105/419 (25%), Positives = 120/419 (28%), Gaps = 120/419 (28%) Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYE 143 G GG QPGP E+ + G GQ PG P PG Sbjct: 1152 GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGP----------------- 1194 Query: 144 HPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSP 203 PGL L Q+ +PG G P G PG + P F G Q P Sbjct: 1195 -PGLPGLSGQKGDGGLPGIPGNP-----------------GLPGPKGEPGFHGFPGVQGP 1236 Query: 204 GMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSG 263 G PGS P +G P Q PG RPG G G G G Sbjct: 1237 ------------PGPPGSPGPALEGPKGNPGPQ--GPPG--RPGFQGLPGPEGPPGLPGN 1280 Query: 264 GGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQG-GGMMM 322 GG G G G G G G G+ +P + G GM Sbjct: 1281 GGIKGEKGNPGQPGL----------------PGLPGLKGDQGPPGLQGNPGRPGLNGMKG 1324 Query: 323 GPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEY 382 PG G GF G + P A P P Sbjct: 1325 DPGLPGVP------------GFPGMKGPSGVPGSAGPE-----------------GEPGL 1355 Query: 383 SSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPA 442 P PP P P Q+ AG GL G Q P P Sbjct: 1356 IGPPGPPGLPG-PSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPG---------PT 1405 Query: 443 MSPGTPG----PTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGP 497 PG PG P + G DP G+ P ++ P P G GPPGP Sbjct: 1406 GPPGDPGRNGLPGFDGAGGRKGDP---------GLPGQPGTRGLDGPPGPDGLQGPPGP 1455 Score = 54.3 bits (129), Expect = 1e-06 Identities = 165/699 (23%), Positives = 217/699 (31%), Gaps = 154/699 (22%) Query: 230 EGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAA 289 EG+P PG+ P G G G G G G G G G Sbjct: 56 EGHPG-----LPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMP 110 Query: 290 AAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAG 349 G G G G + G P G + GP G K GS G Sbjct: 111 GHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSII--MSSLPG 168 Query: 350 QNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQ 409 +P P Q L P+ + G P PP PP P G Sbjct: 169 PKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPP--GLMGPPGPPGLP------------GP 214 Query: 410 QAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQ 469 + G+ G + Q P PG PG Q P+D K Q Sbjct: 215 KGNMGLNFQGPKGEK---------GEQGLQGP---PGPPGQIS--EQKRPIDVEFQKGDQ 260 Query: 470 LYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWK 529 G+ + + P P G GPPGP PG G + Q + Sbjct: 261 --GLPGD------RGPPGPPGIRGPPGP-----------PGGEKGEKGEQGE-------- 293 Query: 530 ETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQE 589 P + G+ G G + QP P LP Y P + P +D ++ Sbjct: 294 ------PGKRGKPGKDGE---------NGQPGIPGLPGDPGY-PGE------PGRD-GEK 330 Query: 590 GYGTRSQPPLAPGK--PNHEDLNLIQQERPSSLPDLSGSIDDL-------PTGTEATLSS 640 G + PP PG P I ++ LP L G + P G + Sbjct: 331 GQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGA 390 Query: 641 AVSAS-------GSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPS-PSPVGSPVGSNQSR 692 AV G +GD+ P S P P L PG P P P G P G + Sbjct: 391 AVMGPPGPPGFPGERGQKGDEGPPGISIPGP---PGLDGQPGAPGLPGPPG-PAGPHIPP 446 Query: 693 SGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQT 752 S I PG PP PPGS + + E+G + G + + G + Sbjct: 447 SDEICE---PG---PPGPPGSPGDKG---------LQGEQG-VKGDKGDTCFNCIGTGIS 490 Query: 753 GPSMSPH----PSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSAS 808 GP P P P G + ++ + T GP+G P A G P Sbjct: 491 GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGAT--------GPKGLPGIPGA-PGAPGFP 541 Query: 809 YSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSA----GMQNRPFP-GNMSSMT---- 859 S PG ++ +G GA L +P G+ P P G +T Sbjct: 542 GSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGE 601 Query: 860 ---PSSPGM-------SQQGGPGMGPPMPTVNRKAQEAA 888 P +PG+ G PG GPP P + Q A Sbjct: 602 RGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVA 640 Score = 47.4 bits (111), Expect = 2e-04 Identities = 72/267 (26%), Positives = 85/267 (31%), Gaps = 46/267 (17%) Query: 79 NNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPA 138 + L G G PGP E HG G PPGPP PG + P P Sbjct: 1206 DGGLPGIPGNPGLPGPKGEPGFHG------FPGVQGPPGPP--GSPGPALEGPKGNPGPQ 1257 Query: 139 G--GRYEHPGLGALGTQQPPVAVPGGGG--------GPAAVPEFNNYYGSAAPAS-GGPG 187 G GR PG L + P +PG GG G +P G P G Sbjct: 1258 GPPGR---PGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNP 1314 Query: 188 GRAGPCFDQHGGQQSPGMGMM--HSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSR 245 GR G +G + PG+ + +G PGS P EG P Sbjct: 1315 GRPG----LNGMKGDPGLPGVPGFPGMKGPSGVPGSAGP-----EGEPGL-------IGP 1358 Query: 246 PGAGGGGGGGG------GGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGG 299 PG G G G G G G G G G G G G G Sbjct: 1359 PGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPG 1418 Query: 300 YGGSSAGYGVLSSPRQQGGGMMMGPGG 326 + G+ G P Q G + GP G Sbjct: 1419 FDGAGGRKGDPGLPGQPGTRGLDGPPG 1445 Score = 40.4 bits (93), Expect = 0.019 Identities = 69/295 (23%), Positives = 92/295 (31%), Gaps = 36/295 (12%) Query: 633 GTEATLSSAVSASGSTSSQGDQSNPA-------QSPFSPHASPHLSSIPGGPSPSPVGSP 685 G++ S G G + +P + P P IPG P P + P Sbjct: 35 GSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGP 94 Query: 686 VGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGF--MAGTQRNPQ 743 G P +PG PG Q + + P GF + G P Sbjct: 95 PGLPGFPGTP----GLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPG 150 Query: 744 MAQYGPQQTGPSMSPHPSP-GGQMHAGISSFQ-QSNSSGTYGPQMSQYGPQGNYSRPPAY 801 + + MS P P G + G Q +G GP GP G PP Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGP----IGPPG----PPGL 202 Query: 802 SGVPSASYSGPGPGM-GISANNQMHGQGPSQPCGAV----PLGRMPSAGMQNRPFPGNMS 856 G P GP PG+ G N ++ QGP G P G Q RP Sbjct: 203 MGPP-----GP-PGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQ 256 Query: 857 SMTPSSPG-MSQQGGPGM-GPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGM 909 PG G PG+ GPP P K ++ + + PG+ Sbjct: 257 KGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGI 311 Score = 33.5 bits (75), Expect = 2.4 Identities = 87/354 (24%), Positives = 111/354 (31%), Gaps = 58/354 (16%) Query: 1101 GEEPPPEVFSTGDTKKQPKLQ----PPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPT 1156 G+ P + T K QP L P P + GP P + G +PG+ P Sbjct: 1101 GDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGP--PGNPG------LPGEPGPVG 1152 Query: 1157 PASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMP 1216 P P + G+ + P + P + P P G+S G +P Sbjct: 1153 GGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGN--PGPPGLPGLSGQKGDGGLP 1210 Query: 1217 YEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGAS 1276 P G + PG QG + P G G R F Sbjct: 1211 GIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGF----- 1265 Query: 1277 YDRRHEPYGQQYPGQGPPSGQPPYGG--------HQPGLYPQQPNYKRHMDGMYGPPAKR 1328 Q PG P G P GG QPGL P P K G GPP Sbjct: 1266 ---------QGLPGPEGPPGLPGNGGIKGEKGNPGQPGL-PGLPGLK----GDQGPPG-- 1309 Query: 1329 HEGDMYNMQYSSQQQEMYNQYG--GSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIP 1386 +Q + + + G G P ++G P S PG I G P Sbjct: 1310 -------LQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPG-P 1361 Query: 1387 PQMMGGPLQSSSSEG----PQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMN 1436 P + G QS +G P +P P Q QG GPT P PG N Sbjct: 1362 PGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGP-QGPQGLPGPTGPPGDPGRN 1414 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 91.7 bits (226), Expect = 7e-18 Identities = 202/933 (21%), Positives = 300/933 (32%), Gaps = 139/933 (14%) Query: 87 GGAPQPGPDMEQPQHGGAKDSAAGGQADP-----PGPPLLSKPGDEDDAPPKMGEPAGGR 141 GG P P S GG A P P PP ++ P PK G PA Sbjct: 975 GGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPS------PK-GSPAATP 1027 Query: 142 YEHPGLGALGTQQPPVAVPGGG-GGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQ 200 + G PP A P G PAA P PA+ P + GP G Sbjct: 1028 FPK------GASTPPAATPPSPKGSPAATPLPKG--APTTPAATLPSPKGGPATPSLKGA 1079 Query: 201 QSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGG 260 +P P + P P+ + P + P + GG G Sbjct: 1080 PTP---------------PAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKG 1124 Query: 261 GSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVL--SSPRQQGG 318 + GG A AA GG G ++P G Sbjct: 1125 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1184 Query: 319 GMMMGPGGGGAASLSKAAAGSAAGGFQRFA--GQNQHPSGATPTLNQLLTSPSPMMRSYG 376 G+ P GA + A S GG + G P+ P+ L +PSP G Sbjct: 1185 GLAT-PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK----G 1239 Query: 377 GSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAA--SPAWAA 434 ++P +P P+ P + A AA G+ GA A P+ Sbjct: 1240 APTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG 1299 Query: 435 AQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGP 494 S P +P P T +GSP P P + +P P + P Sbjct: 1300 GPATSPPKGAPTPPAATPPSPKGSPGTP------------------PPKGAPTPP-AVTP 1340 Query: 495 PGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQP 554 P P+ P + TP + G P ++ PP G P Sbjct: 1341 PSPKGTPT-LPATTPSSKGGPTTPSSKEGPT----------PPAATPSHKGGPAMTPPSP 1389 Query: 555 YYSQQ-PQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQ 613 P P P +P ++ P +++EG T S+ L P P ++L + Sbjct: 1390 KRGPAIPSPKGDPTSPAVIPLSPKKA--PATPVTREGAATPSKGDLTP--PAVTPVSLKK 1445 Query: 614 QERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSI 673 S+ P G AT SS+GD + PA +P SP P + Sbjct: 1446 APATSA-----------PKGGPAT----------PSSKGDPTLPAVTPPSPKEPPAPKQV 1484 Query: 674 PGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERG 733 SP + P +PA + +P P S E + P+ + P+ Sbjct: 1485 ATSSSP------------KKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTAT 1532 Query: 734 FMAG---TQRNPQMAQYGPQQTGPSMSPHPS-PGGQMHAGISSFQQSNSSGTYGPQMSQY 789 ++ P+ A P T PS P+ P + S ++++S P + Sbjct: 1533 LLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKG 1592 Query: 790 GPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNR 849 P P PS + P + + + GP+ P P + Sbjct: 1593 APSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEK----GPATPAPKGTPTSPPVTPSSLK 1648 Query: 850 PFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGM 909 P + +S+T Q G+ K A A +A +R+G Sbjct: 1649 DSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGP---- 1704 Query: 910 NQSGLMASSSPYSQP----MNNSSSLMNTQAPPYSMAPAMVNSSAASVGL------ADMM 959 Q+ +++SP P N S ++T AP + P +SS + G + Sbjct: 1705 -QTKKSSATSPPICPDPSAKNGSKGPLSTVAPA-PLLPVQKDSSKTAKGKDASHSPKGPL 1762 Query: 960 SPGESKLPLPLKADGKEEGTPQPESKSKKSSSS 992 +P ESK PL A E+ P+PES S ++ S Sbjct: 1763 APPESKASTPLTAAAFEKVLPKPESASVSAAPS 1795 Score = 75.1 bits (183), Expect = 7e-13 Identities = 209/971 (21%), Positives = 315/971 (32%), Gaps = 204/971 (21%) Query: 621 PDLSGSIDDLPT------GTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIP 674 P L G++ P GT TL +AS + N + +P + Sbjct: 675 PFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSV 734 Query: 675 GGPSPSPVGSPVGSNQ----SRSGPISPASIPGSQMPPQPPGSQSESSSHPA---LSQSP 727 PS P G+P G+ + S + ++P + + P + G+ + +SS L+ SP Sbjct: 735 PSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSP 794 Query: 728 MPQERGFMAGTQRNP-QMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQM 786 P T+R P + GP ++S SP +SF NS G Sbjct: 795 SPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVE------ASFLPENSLSFQG--- 845 Query: 787 SQYGPQGNYS-RPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAG 845 S+ P +S PP+ G P+ S P G++ +P P+ Sbjct: 846 SKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVT----------------LPPKETPTPS 889 Query: 846 MQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGS 905 + N PFP GP P A + A A+ +++ ++R Sbjct: 890 VVNLPFPKE-------------------GPATP-----APKQAPALSMTSSSPKKARATP 925 Query: 906 FPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSP-GES 964 P G+ AS SP P +++ + + P + +P + A A SP G Sbjct: 926 AP----KGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPA----ATPPSPKGGP 977 Query: 965 KLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEE 1024 P P A TP P K ++ S V T Sbjct: 978 ATPSPKGAPTPPAATP-PSPKGGPATPSPKGAPTPPAV-----------------TPPSP 1019 Query: 1025 RGSPVSS-LPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSL 1083 +GSP ++ P P A + K AT L G ++ A++L Sbjct: 1020 KGSPAATPFPKGASTP---------------PAATPPSPKGSPAATPLPKGAPTTPAATL 1064 Query: 1084 KKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSN 1143 +G PP T PK P +P+ G+ P + Sbjct: 1065 PSP----KGGPATPSLKGAPTPPAA-----TPPSPKGGPATPSPKGAPMPPAATPPSPKG 1115 Query: 1144 SMAEVPGDLKPPTPASTP----HGQMTPMQGGRSSTISVHDP-----FSDVSDSSFPKRN 1194 +A P P TPA+TP G TP G +T + P + P Sbjct: 1116 GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1175 Query: 1195 SMTPNAPYQQGMSMPDVMG--RMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMY 1252 + TP +P + G++ P G P P GG+ P T P S + Sbjct: 1176 AATPPSP-KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP-TTPAATPPSPKGGLA 1233 Query: 1253 NQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQP 1312 SP GA + P +G P+ PP G P P Sbjct: 1234 TPSPKGAPTT--------------------PAATPPSPKGGPATPPPKGAPTPPA-ATPP 1272 Query: 1313 NYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQ-------- 1364 + K G+ PP K S + + G+ + P P + Sbjct: 1273 SLK---GGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPP 1329 Query: 1365 --YPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQG 1422 P P + G P GGP SS EGP P Sbjct: 1330 KGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP-----------PAATPSH 1378 Query: 1423 PGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITR----PP 1478 GGP PP P +P + + S P+ + P A P+TR P Sbjct: 1379 KGGPAMTPPSPKRGPA----IPSPKGDPTS--PAVI----PLSPKKAPATPVTREGAATP 1428 Query: 1479 QPSYQTPPSL-PNHISRAPSPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGP 1537 TPP++ P + +AP+ + +P P PS K PT+P VT P Sbjct: 1429 SKGDLTPPAVTPVSLKKAPATS----------APKGGPATPSSKGD---PTLPA--VTPP 1473 Query: 1538 PPQPPPIRREI 1548 P+ PP +++ Sbjct: 1474 SPKEPPAPKQV 1484 Score = 70.5 bits (171), Expect = 2e-11 Identities = 215/1020 (21%), Positives = 327/1020 (32%), Gaps = 168/1020 (16%) Query: 617 PSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQS------PFSPHASPHL 670 P D +G GT ++A T S +++P + P P AS Sbjct: 649 PLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTAS--- 705 Query: 671 SSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQ--PPGSQ-----SESSSHPAL 723 + P PSP +P+ + P P S+P +PP PPG++ S +S+ + Sbjct: 706 ENCPVAPSPQNTCAPLATLVL--APEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPV 763 Query: 724 SQSPM--PQERGFMAGTQRNPQMAQY---GPQQTGPSMSPHPSPGGQMHAGISSFQQSNS 778 + SP P E + T + Y P G S+SP + Sbjct: 764 ASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTK------------RPPTK 811 Query: 779 SGTYGPQMSQYGPQGNYSRPPA---YSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGA 835 G+ GP P GN S P + S +P S S G + H P P GA Sbjct: 812 KGSAGPDT----PIGNLSSPVSPVEASFLPENSLSFQGSKDSPATT---HSPTPPSPKGA 864 Query: 836 VPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAA 895 PSA P + +P + P GP P A + A A+ + Sbjct: 865 PT----PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP-----APKQAPALSMTS 915 Query: 896 ANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGL 955 ++ ++R P G+ AS SP P +++ + + P + +P + A+ Sbjct: 916 SSPKKARATPAP----KGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPP 971 Query: 956 ADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWV 1015 + P P P A TP P K ++ S V Sbjct: 972 SPKGGPAT---PSPKGAPTPPAATP-PSPKGGPATPSPKGAPTPPAV------------- 1014 Query: 1016 DRYLTFMEERGSPVSS-LPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVG 1074 T +GSP ++ P P A + K AT L G Sbjct: 1015 ----TPPSPKGSPAATPFPKGASTPP---------------AATPPSPKGSPAATPLPKG 1055 Query: 1075 TSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGP 1134 ++ A++L +G PP T PK P +P+ G+ P Sbjct: 1056 APTTPAATLPSPK----GGPATPSLKGAPTPPAA-----TPPSPKGGPATPSPKGAPMPP 1106 Query: 1135 QTPQSTGSNSMAEVPGDLKPPTPASTPH----GQMTPMQGGRSSTISVHDP-----FSDV 1185 + +A P P TPA+TP G TP G +T + P + Sbjct: 1107 AATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP 1166 Query: 1186 SDSSFPKRNSMTPNAPYQQGMSMPDVMGR--MPYEPNKDPFGGMRKVPGSSEPFMTQGQM 1243 P + TP +P + G++ P G P P GG+ P T Sbjct: 1167 PPKGAPTTPAATPPSP-KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP-TTPAAT 1224 Query: 1244 PNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGH 1303 P S + SP GA + P +G P+ PP G Sbjct: 1225 PPSPKGGLATPSPKGAPTT--------------------PAATPPSPKGGPATPPPKGAP 1264 Query: 1304 QPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQG 1363 P P+ K G+ PP K S + + G+ + P P Sbjct: 1265 TPPA-ATPPSLK---GGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSP 1320 Query: 1364 Q----------YPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARND- 1412 + P P + G P GGP SS EGP + Sbjct: 1321 KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG 1380 Query: 1413 --MPYPYQNRQGPGGPTQA--PPYPGMNRTDDMMVPDQRINHE-SQWPSHVSQRQPYMS- 1466 P ++GP P+ P P + P + E + PS P ++ Sbjct: 1381 GPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTP 1440 Query: 1467 -----SSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPSMK 1521 + A+ P P PS + P+LP +P + + SP K+P P+ Sbjct: 1441 VSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPM 1500 Query: 1522 MQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRKITSKDIVTPEAWRV 1581 +P V S P P RR+ P ++ + K + K+ + P A V Sbjct: 1501 GAPTLPAVIPSS-PKEVPATPSSRRDPIAPTATLLSK----KTPATLAPKEALIPPAMTV 1555 Score = 67.4 bits (163), Expect = 1e-10 Identities = 122/518 (23%), Positives = 176/518 (33%), Gaps = 82/518 (15%) Query: 380 PEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRS 439 P + PP P P A + G + + PA A +Q Sbjct: 850 PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQA- 908 Query: 440 HPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQR 499 PA+S + P R+ +P + P G + P + P P P G P P+ Sbjct: 909 -PALSMTSSSPKKARATPAPKG--IPASPSPKGAPTPPAATP----PSPKGGPATPSPKW 961 Query: 500 YPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQ 559 P TP A P G AT PP G P Sbjct: 962 AP------TPPAAT----PPSPKGGPATPSPKGAPTPPAATPPSPKG---GPATPSPKGA 1008 Query: 560 PQPPHL-PPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPS 618 P PP + PP + P+ + P+ G + P P P P+ Sbjct: 1009 PTPPAVTPPSPKGSPAATPF---PK--------GASTPPAATPPSPKGS---------PA 1048 Query: 619 SLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGP- 677 + P G+ PT ATL S + S +G + PA +P SP P S G P Sbjct: 1049 ATPLPKGA----PTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPM 1104 Query: 678 -----SPSPVGSPVGSNQSRSGPISPASIP----GSQMPPQPPGSQSESSSHP-----AL 723 PSP G + + + P +PA+ P G P P G+ + ++ P L Sbjct: 1105 PPAATPPSPKGG-LATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1163 Query: 724 SQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSP---HPSPGGQMHAGISSFQQSNSSG 780 + P A T +P+ P G +P PSP G G+++ + Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG----GLATPSPKGAPT 1219 Query: 781 TYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGR 840 T P + P+G + P+ G P+ + P G A G P+ P P Sbjct: 1220 T--PAATPPSPKGGLA-TPSPKGAPTTPAATPPSPKGGPATPPPKG-APTPPAATPP--- 1272 Query: 841 MPSAGMQNRPFPG--NMSSMTPSSPGMSQQGGPGMGPP 876 G+ P G N + +TP SP +GGP PP Sbjct: 1273 SLKGGLATPPHKGAPNPAVVTPPSP----KGGPATSPP 1306 Score = 45.4 bits (106), Expect = 6e-04 Identities = 114/534 (21%), Positives = 176/534 (32%), Gaps = 69/534 (12%) Query: 1104 PPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPA---ST 1160 PPP+ T P PPSP + P+ +T + + G L P+P +T Sbjct: 1166 PPPKGAPT-----TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1220 Query: 1161 PHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTP---NAPYQQGMSMPDVMGRMPY 1217 P +GG ++ P + + PK TP AP + P + G + Sbjct: 1221 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLAT 1280 Query: 1218 EPNK-----------DPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMG 1266 P+K P GG P P P S P GA + + Sbjct: 1281 PPHKGAPNPAVVTPPSPKGGPATSPPKGAP-TPPAATPPSPKGSPGTPPPKGAPTPPAVT 1339 Query: 1267 QRQQFPYGASYDRRHEPYGQQYP-------GQGPPSGQPPYGGHQPGLYPQQPNYKRHMD 1319 P G P + P G PP+ P + G P + P P + Sbjct: 1340 PPS--PKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGG-PAMTPPSPKRGPAIP 1396 Query: 1320 GMYGPPAKRHEGDMYNMQYSSQ---QQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQG 1376 G P + + + ++ G + P P+ + P + G Sbjct: 1397 SPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKA-PATSAPKGG 1455 Query: 1377 PGQIQTHGIP---------PQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPT 1427 P + G P P+ P Q ++S P++ A M P P P Sbjct: 1456 PATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAP-ATPAPMGAPTLPAVIPSSPK 1514 Query: 1428 QAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQ--PSYQTP 1485 + P P R D + P + +S++ P ++ A + + P PS + Sbjct: 1515 EVPATPSSRR--DPIAPTATL---------LSKKTP--ATLAPKEALIPPAMTVPSPKKT 1561 Query: 1486 PSLPNHISRAPSPASFQRSLENRMSPSKSPFLPSMKMQKVMPTV----PTSQVTGPPPQP 1541 P++P +P+S + S ++PS PS K + P V P T P P Sbjct: 1562 PAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTP 1621 Query: 1542 P-PIRREITFPPGSVEASQPVLKQRRK--ITSKDIVTPEAWRVMMSLKSGLLAE 1592 P P + T P S PV K TS VT + + GL A+ Sbjct: 1622 PSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAK 1675 Score = 43.9 bits (102), Expect = 0.002 Identities = 274/1278 (21%), Positives = 410/1278 (32%), Gaps = 220/1278 (17%) Query: 365 LTSPSPMMRSYGGSYPEYSSPSAPP------PPPSQPQSQAAAAGAAA----GGQQAAAG 414 L P P S G + P ++P AP PP P + A A+ A G ++A Sbjct: 78 LEVPFPQSSS-GTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAP 136 Query: 415 MGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMG 474 + L + S A+ S P+++ G + S +P+ P K Sbjct: 137 LALVA-LAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLS--APIAPSEPK-------- 185 Query: 475 SNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKET--- 531 +N + P + P P G+ PP + TP MA +Q SG A+ +T Sbjct: 186 TNLNKVPSEVVPNPKGTPSPPCIVS-TVPYHCVTP--MASIQ------SGVASLPQTTPT 236 Query: 532 --FWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQE 589 + PQ +S Q P S + P PP A L +QS P SQ+ Sbjct: 237 TTLAIASPQVKDTTISSVLISPQNPG-SLSLKGPVSPPAALSLSTQSL----PVVTSSQK 291 Query: 590 GYGTRSQP--PLAPGK---PNHED----LNLIQQERPSSLPDLSGSIDDLPTGTEATLSS 640 G + P P++ G P H+ + L+ Q PS+L D T T+S Sbjct: 292 TAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSD----------PTVKTISV 341 Query: 641 AVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPAS 700 S++G+ S P+Q P +P + PV +P GP + +S Sbjct: 342 DHSSTGA-------SYPSQRSVIPPLPSRNEVVPATVAAFPVVAP----SVDKGPSTISS 390 Query: 701 IPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHP 760 I S P GS + ++S +LS + + T P +AQ G + Sbjct: 391 ITCS-----PSGSLNVATSF-SLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVT 444 Query: 761 SPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISA 820 +P A ++F+ + P MS GP N P + + + A + P ++ Sbjct: 445 NPCTIAAAPTTTFEVATC---VSPPMSS-GPISNIE-PTSPAALVMAPVAPKEPSTQVAT 499 Query: 821 NNQMHGQGPSQPCGAVP--LGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMP 878 ++ P P P L +PS+ + P ++ ++ S +G P P Sbjct: 500 TLRI----PVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASL-----EGAP-FSPAQA 549 Query: 879 TVNRKAQEAAAAVMQAAANSAQSRQG--SFPGMNQS----------------GLMASSSP 920 + K ++QAA ++ S Q S P + S G ASS Sbjct: 550 GLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMT 609 Query: 921 YSQPMNNSSSLMNTQ--APPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKE-- 976 +N+S+S++ T A P S P + +S A + + P A G Sbjct: 610 SPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTY 669 Query: 977 --------EGTPQPESKSKKSSSSTTTGEKITKVYE----LGNEPERKLWVDRYLTFMEE 1024 EGT K+ T T + + P+ L E Sbjct: 670 TTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPE 729 Query: 1025 --RGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASS 1082 + P SLP G P K++ G++ + S ++A++ Sbjct: 730 IPKSVPSPSLPPAGTPP--------GTKKVDGISHTSALAPVASSPKECPTEDSGASATA 781 Query: 1083 LKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANS---GSLQGPQTPQS 1139 K + YL + P P S K+P + S G+L P +P Sbjct: 782 SSKGTLTYL---------ADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVE 832 Query: 1140 TG---SNSMA-----EVPGDLKPPTPASTPHGQMTPMQGGRSSTISV-----HDPFSDVS 1186 NS++ + P PTP S P G TP S V P V Sbjct: 833 ASFLPENSLSFQGSKDSPATTHSPTPPS-PKGAPTPSAVTPLSPKGVTLPPKETPTPSVV 891 Query: 1187 DSSFPKRNSMTP---NAPYQQGMSMPDVMGRMPYEPNKDPFG----GMRKVPGSSEPFMT 1239 + FPK TP AP S R P P G P ++ P Sbjct: 892 NLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPK 951 Query: 1240 QGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPP 1299 G P + P+ + G P GA P P GP + P Sbjct: 952 GG--PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP---PSPKGGPATPSPK 1006 Query: 1300 YGGHQPGLYPQQPN----YKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSG 1355 P + P P G PPA + + + + Sbjct: 1007 GAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS 1066 Query: 1356 PDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPY 1415 P P P + P PP GGP S P MP Sbjct: 1067 PKGGPAT-----PSLKGAPTPPA-----ATPPSPKGGPATPSPKGAP----------MP- 1105 Query: 1416 PYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPIT 1475 P P G PP+ G T P + + P A P Sbjct: 1106 PAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPP-----------KGAPTTPAA 1154 Query: 1476 RPPQP--SYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQ 1533 PP P TPP + A +P S + L SP +P P+ P P Sbjct: 1155 TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT-PSPKGAPTTPA-----ATPPSPKGG 1208 Query: 1534 VTGPPPQPPPIRREITFP 1551 + P P+ P T P Sbjct: 1209 LATPSPKGAPTTPAATPP 1226 >gi|62122917 filaggrin family member 2 [Homo sapiens] Length = 2391 Score = 91.3 bits (225), Expect = 1e-17 Identities = 206/877 (23%), Positives = 278/877 (31%), Gaps = 139/877 (15%) Query: 102 GGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEH-PGLGALGTQQPPVAVP 160 G +GGQ G P S P + + G G+ ++ G G+ Q Sbjct: 324 GQGHGCVSGGQPSGCGQPE-SNPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCGQ 382 Query: 161 GGGGGPAAVPEFNNYYGSAAPASG-------------GPGGRAGPCFDQHGG--QQSPGM 205 G GG + + YGS S G G F+QHG QS G Sbjct: 383 YGSGGSQSCSNGQHEYGSCGRFSNSSSSNEFSKCDQYGSGSSQSTSFEQHGTGLSQSSGF 442 Query: 206 GMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGG-GGGGGGSGG 264 S G HE S + GY + G+ G G G G GSG Sbjct: 443 EQHVCGSGQTCG----------QHE----STSSQSLGYDQHGSSSGKTSGFGQHGSGSGQ 488 Query: 265 GGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGV------LSSPRQQGG 318 G G G+G + + + ++G G G G S+G+G SS Q G Sbjct: 489 SSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSYGQHGS 548 Query: 319 GMMMGPGGG-------------GAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLL 365 G G G G S G G + +G QH SG+ Q Sbjct: 549 GSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGS----GQSS 604 Query: 366 TSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQ--------AAAAGAAAGGQQAAAGMGL 417 RS SY ++SS S+ Q S+ + + + G Q +G G Sbjct: 605 GFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQ 664 Query: 418 GKDMGAQYAAASPAWAAAQQRSHPAMSP-GTPGPTMGRSQGSPMDPMVMKRPQLYGMGSN 476 G + + + Q S S G G G SQ S Q G G + Sbjct: 665 SSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHG--FGSSQSSGYGQHGSSSGQTSGFGQH 722 Query: 477 PHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKE--TFWL 534 S Q SS G +G Q G G G +G + + SG +++ + + Sbjct: 723 ELSSGQSSS---FGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESR-SGQSSYGQHSSGSS 778 Query: 535 MPPQYGQQG---VSGYCQQGQQP--------YYSQQPQPP----HLPPQAQYLPSQSQQR 579 YGQ G SG+ Q G Y S Q H Q + Sbjct: 779 QSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHES 838 Query: 580 YQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLS 639 Q Q G G+ + + Q R SS +G + Sbjct: 839 RSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFG 898 Query: 640 SAVSASGSTSSQGD-QSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISP 698 + SG S G +S QS + H S S G S G G Q RSG Sbjct: 899 QHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGS--- 955 Query: 699 ASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSP 758 G GS S SS +S + GF R+ Q + YG +G S S Sbjct: 956 ----GQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQ-SNYGQHGSGSSQSS 1010 Query: 759 ----HPSPGGQ------------MHAGI----SSFQQSNSSGTYGP---QMSQYGPQGNY 795 H S GQ ++G S QS+ G +G Q S +G + Sbjct: 1011 GYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESR 1070 Query: 796 SRPPAYS--GVPSASYSGPG----------------PGMGISANNQMHGQGPSQPCGAVP 837 SR +Y G S+ SG G PG G S+ +G G Q G Sbjct: 1071 SRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQ 1130 Query: 838 --LGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPG 872 G S+G + SS G SQ G G Sbjct: 1131 HGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCG 1167 Score = 87.8 bits (216), Expect = 1e-16 Identities = 204/921 (22%), Positives = 291/921 (31%), Gaps = 137/921 (14%) Query: 60 QQQQQQQQQQQQQQHPISNNNSLG--------GAGGGAPQPGPDMEQP----QHGGAKDS 107 Q + Q QH S+ + G G G Q G Q QHG Sbjct: 455 QHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQ 514 Query: 108 AAG-GQ-ADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGG 165 ++G GQ G + G+ G + G G G+++ G G Sbjct: 515 SSGFGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETS-GFGQHGLG 573 Query: 166 PAAVPEFNNYYGSAAPASG----GPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGS 221 F Y + +SG G G F QH + HS+ ++ + G Sbjct: 574 SGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQ 633 Query: 222 MDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAV 281 Q S G S + G+ + G+G G G G G G G +G + Sbjct: 634 HGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSY 693 Query: 282 AAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAA 341 ++ ++G G G G ++G+G + G G G+ S + G Sbjct: 694 GQHGFGSSQSSGYGQHGSSSGQTSGFG----QHELSSGQSSSFGQHGSGSGQSSGFGQHG 749 Query: 342 GGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQS-QAA 400 G + +G QH S RS SY ++SS S+ Q S Q + Sbjct: 750 SGSGQSSGFGQHES-----------------RSGQSSYGQHSSGSSQSSGYGQHGSRQTS 792 Query: 401 AAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPM 460 G G + G G QY + S A Q + G RS S Sbjct: 793 GFGQHGSGSSQSTGFG-------QYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSY 845 Query: 461 DPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQ 520 +G GS+ QSS Y G +G Q G + G +G Q Sbjct: 846 GQ--------HGSGSS------QSSGY--GQHGSSSGQTSGFGQHRSSSGQYSGFG---Q 886 Query: 521 QDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRY 580 SG +GQ G GQ + Q H Q+ SQ Sbjct: 887 HGSGSG--------QSSGFGQHGTGS----GQYSGFGQHESRSHQSSYGQHGSGSSQS-- 932 Query: 581 QPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSS 640 GYG G + + Q S G +G + Sbjct: 933 --------SGYGQH-------GSSSGQTFGFGQHRSGSGQSSGFGQHGS-GSGQSSGFGQ 976 Query: 641 AVSASGSTSSQGD-QSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPA 699 S SG +S G +S +QS + H S S G S G G Q RS Sbjct: 977 HESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSS---- 1032 Query: 700 SIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSP- 758 G GS S+ SS + Q GF R+ Q + YG +G S S Sbjct: 1033 ---GQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQ-SSYGQHGSGSSQSSG 1088 Query: 759 ---HPSPGGQMHAGISSFQ----QSNSSGTYGP---QMSQYGPQGN-------YSRPPAY 801 H S GQ +G + QS+ G YG Q S +G G+ +++ Sbjct: 1089 YGQHGSNSGQT-SGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYR 1147 Query: 802 SGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLG--RMPSAGMQNRPFPGNMSSMT 859 SG S G G G GP+ G G S+G Q+ G + Sbjct: 1148 SGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSG-QHISDSGQSTGFG 1206 Query: 860 PSSPGMSQQGGPGMGPPM-----PTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGL 914 G Q G G G TV+ + + + +S QS QG Q+G Sbjct: 1207 QYGSGSGQSTGLGQGESQQVESGSTVHGRQETTHGQTINTTRHS-QSGQGQ---STQTGS 1262 Query: 915 MASSSPYSQPMNNSSSLMNTQ 935 + S NS S ++++ Sbjct: 1263 RVTRRRRSSQSENSDSEVHSK 1283 Score = 73.6 bits (179), Expect = 2e-12 Identities = 156/780 (20%), Positives = 245/780 (31%), Gaps = 91/780 (11%) Query: 60 QQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPP 119 Q Q QH + G G G+ Q Q G + S G G Sbjct: 620 QHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQ-STGFGQYGSGSGQSSGFGQHVSGSGQS 678 Query: 120 LLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSA 179 + G+ G + G G G+ + G + +GS Sbjct: 679 SGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSG 738 Query: 180 APASGG-----PGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPN 234 + S G G F QH + HS+ ++ + G Q S G Sbjct: 739 SGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHG 798 Query: 235 SQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGG 294 S + G+ + G+G G G G G G G G + + + ++ ++G Sbjct: 799 SGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGY 858 Query: 295 GGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHP 354 G G G ++G+G + G G G G+ S + G G +++G QH Sbjct: 859 GQHGSSSGQTSGFG----QHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHE 914 Query: 355 SGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQA----------AAAGA 404 S RS+ SY ++ S S+ Q S + + +G Sbjct: 915 S-----------------RSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQ 957 Query: 405 AAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSP-GTPGPTMGRSQGSPMDPM 463 ++G Q +G G G + + + Q S + S G G G SQ S Sbjct: 958 SSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHG--SGSSQSSGYGQH 1015 Query: 464 VMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGM-QYPQQQD 522 Q G G + S Q S G +G Q G G G +G QY + Sbjct: 1016 GSSSGQTTGFGQHRSSSGQYSG---FGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSR 1072 Query: 523 SGDATWKETFWLMPPQYGQQG-----VSGYCQQGQQP-----YYSQQPQPPHLPPQAQYL 572 YGQ G SGY Q G + +P QY Sbjct: 1073 QS-------------SYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYG 1119 Query: 573 PSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPT 632 Q Q G GT A + + Q SS G + + Sbjct: 1120 SGSGQ-----SSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQ-HESGS 1173 Query: 633 GTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSR 692 G + VS S + SS G H S S G S G G Q Sbjct: 1174 GPTTSFGQHVSGSDNFSSSGQ-----------HISDSGQSTGFGQYGSGSGQSTGLGQGE 1222 Query: 693 SGPI-SPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQ 751 S + S +++ G Q + Q+ +++ + S + G +R ++ + Sbjct: 1223 SQQVESGSTVHGRQ---ETTHGQTINTTRHSQSGQGQSTQTGSRVTRRRRSSQSENSDSE 1279 Query: 752 TGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSG 811 +S S +H S + S Q + +G +G+ +R +SG ++ +G Sbjct: 1280 VHSKVSHRHSE--HIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTR-HGHSGHGQSTQTG 1336 Score = 67.8 bits (164), Expect = 1e-10 Identities = 196/871 (22%), Positives = 278/871 (31%), Gaps = 116/871 (13%) Query: 177 GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQ 236 GS+ SG G R+ C G S G G +AS++ Q+ G +Q Sbjct: 264 GSSCSGSGDSGRRSHAC----GYSNSSGCGRPQNASSSC----------QSHRFGGQGNQ 309 Query: 237 CNHYPGYSRPGAGGGGGGGGGGGGGSGGGGG-------------GGGAGAGGA--GAGAV 281 ++ + G GG G G GG G G G GA G G Sbjct: 310 FSYIQSGCQSGIKGGQGHGCVSGGQPSGCGQPESNPCSQSYSQRGYGARENGQPQNCGGQ 369 Query: 282 AAAAAAAAAAAGGGGGGGYGGSSAG---YGVLSSPRQQGGGMMMGP----GGGGAASLSK 334 ++ ++ G G GG S G YG G G + S S Sbjct: 370 WRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEFSKCDQYGSGSSQSTSF 429 Query: 335 AAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQ 394 G+ G + +G QH G+ T Q ++ S + Y ++ S S Q Sbjct: 430 EQHGT---GLSQSSGFEQHVCGSGQTCGQHESTSSQSL-----GYDQHGSSSGKTSGFGQ 481 Query: 395 PQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGR 454 + +G ++G Q +G G G + + + Q S S G G R Sbjct: 482 ---HGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGF-GQHESR 537 Query: 455 SQGSPMDPMVMKRPQLYGMGSNPHSQPQ----------QSSPYPGGSYGPPGPQRYPIGI 504 S+ S Q G G + QS+ + G YG Q G Sbjct: 538 SRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGF--GQYGSGSGQSSGFGQ 595 Query: 505 QGRTPGAMAGMQYPQQQDSGDATWKE--TFWLMPPQYGQQG---VSGYCQQGQQP----- 554 G G +G + + SG +++ + + YGQ G SG+ Q G Sbjct: 596 HGSGSGQSSGFGQHESR-SGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTG 654 Query: 555 ---YYSQQPQPP----HLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHE 607 Y S Q H+ Q + Q G+G+ + Sbjct: 655 FGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSG 714 Query: 608 DLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGD-QSNPAQSPFSPHA 666 + Q SS S +G + S SG +S G +S QS + H+ Sbjct: 715 QTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHS 774 Query: 667 SPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQS 726 S S G S S G + S S + GS Q S S Sbjct: 775 SGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSG------ 828 Query: 727 PMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQM 786 Q GF R+ Q + YG +G S S G S F Q SS Sbjct: 829 ---QSSGFGQHESRSHQ-SSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGF 884 Query: 787 SQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQ--MHGQGPSQPCGAVPLGRMPSA 844 Q+G S G S YSG G S + HG G SQ G G S+ Sbjct: 885 GQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHG--SSS 942 Query: 845 GM-----QNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSA 899 G Q+R G S G Q G G + ++ Q + S+ Sbjct: 943 GQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQ-------HESGSGKSSGFGQHESRSS 995 Query: 900 QSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMM 959 QS G + SG + SS Y Q + SSS T + + + + G Sbjct: 996 QSNY----GQHGSG-SSQSSGYGQ--HGSSSGQTTGFGQHRSS----SGQYSGFGQHGSG 1044 Query: 960 SPGESKLPLPLKADGKEEGTPQPESKSKKSS 990 S S G+ G Q ES+S++SS Sbjct: 1045 SDQSSGFGQHGTGSGQSSGFGQYESRSRQSS 1075 Score = 50.4 bits (119), Expect = 2e-05 Identities = 146/676 (21%), Positives = 210/676 (31%), Gaps = 79/676 (11%) Query: 694 GPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERG--FMAGTQRNPQMAQYGPQQ 751 G +S G P P SQS S ++ PQ G + G+ ++ QYG Sbjct: 328 GCVSGGQPSGCGQPESNPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCGQYG--- 384 Query: 752 TGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSG 811 +G S S S G + F S+SS + + QYG + S S+ Sbjct: 385 SGGSQSC--SNGQHEYGSCGRFSNSSSSNEFS-KCDQYGSGSSQS----------TSFEQ 431 Query: 812 PGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGM-QNRPFPGNMSSMTPSSPGMSQQGG 870 G G+ S+ + H G Q CG S G Q+ G S G Q G Sbjct: 432 HGTGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSG 491 Query: 871 PGM-GPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSS 929 G G + Q + + + S G G Q + S Y Q + SS Sbjct: 492 FGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSS 551 Query: 930 SLMNTQAPPYSMAPAMVNSSAASVGLADMMSPG----------ESKLPLPLKADGKEEGT 979 Q+ Y + S GL S G S G+ G Sbjct: 552 -----QSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGF 606 Query: 980 PQPESKSKKSS-SSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKK 1038 Q ES+S +SS ++G + Y G R+ + + GS S G+ Sbjct: 607 GQHESRSGQSSYGQHSSGSSQSSGY--GQHGSRQT------SGFGQHGSGSSQSTGFGQY 658 Query: 1039 PLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKI 1098 + + + G Q + G + S Y Q+ F Sbjct: 659 GSGSGQSSGFGQHVSGSGQSS--------------GFGQHESRSGHSSYGQHGFGSSQSS 704 Query: 1099 ERGEEPPPEVFSTGDTKK--QPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPT 1156 G+ S+G T Q +L ++ G G + QS+G G Sbjct: 705 GYGQHGS----SSGQTSGFGQHELSSGQSSSFGQ-HGSGSGQSSGFGQHGSGSGQ----- 754 Query: 1157 PASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMP 1216 S+ GQ G S+ H S S S + + S + Q G G Sbjct: 755 --SSGFGQHESRSG--QSSYGQHSSGSSQS-SGYGQHGSRQTSGFGQHGSGSSQSTGFGQ 809 Query: 1217 YEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGAS 1276 Y G + S GQ + S Q Y Q SG+ + G GQ S Sbjct: 810 YGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTS 869 Query: 1277 YDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNM 1336 +H QY G GQ G Q + Q G ++ H+ Sbjct: 870 GFGQHRSSSGQYSG----FGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQH 925 Query: 1337 QYSSQQQEMYNQYGGS 1352 S Q Y Q+G S Sbjct: 926 GSGSSQSSGYGQHGSS 941 Score = 34.3 bits (77), Expect = 1.4 Identities = 43/151 (28%), Positives = 57/151 (37%), Gaps = 23/151 (15%) Query: 1224 FGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQ---RQQFPYG--ASYD 1278 FG G S F GQ + S Q Y Q SG+ + G GQ RQ +G S Sbjct: 745 FGQHGSGSGQSSGF---GQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGS 801 Query: 1279 RRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQY 1338 + +GQ G G +G +G H G Q + +H ++ H+ Sbjct: 802 SQSTGFGQYGSGSGQSAG---FGQHGSG-SGQSSGFGQH-------ESRSHQSSYGQHGS 850 Query: 1339 SSQQQEMYNQYG---GSYSG-PDRRPIQGQY 1365 S Q Y Q+G G SG R GQY Sbjct: 851 GSSQSSGYGQHGSSSGQTSGFGQHRSSSGQY 881 Score = 34.3 bits (77), Expect = 1.4 Identities = 26/78 (33%), Positives = 31/78 (39%), Gaps = 9/78 (11%) Query: 1224 FGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEP 1283 FG G S F GQ + S Q Y Q SG+ + G GQ S + Sbjct: 1051 FGQHGTGSGQSSGF---GQYESRSRQSSYGQHGSGSSQSSGYGQH------GSNSGQTSG 1101 Query: 1284 YGQQYPGQGPPSGQPPYG 1301 +GQ PG G SG YG Sbjct: 1102 FGQHRPGSGQSSGFGQYG 1119 Score = 33.9 bits (76), Expect = 1.8 Identities = 53/208 (25%), Positives = 60/208 (28%), Gaps = 41/208 (19%) Query: 1224 FGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEP 1283 FG V G S F GQ + S Q Y Q G G Q YG R Sbjct: 518 FGQHGSVSGQSSGF---GQHESRSRQSSYGQH--------GSGSSQSSGYGQYGSRETSG 566 Query: 1284 YGQQYPGQGPPSGQPPYG---GHQPGLYPQ------------------QPNYKRHMDGM- 1321 +GQ G G +G YG G G Q +Y +H G Sbjct: 567 FGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSS 626 Query: 1322 ----YGPPAKRHEGDMYNMQYSSQQQEMYNQYG---GSYSGPDRRPI-QGQYPYPYSRER 1373 YG R S Q + QYG G SG + GQ E Sbjct: 627 QSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHES 686 Query: 1374 MQGPGQIQTHGIPPQMMGGPLQSSSSEG 1401 G HG G Q SS G Sbjct: 687 RSGHSSYGQHGFGSSQSSGYGQHGSSSG 714 Score = 33.5 bits (75), Expect = 2.4 Identities = 38/144 (26%), Positives = 54/144 (37%), Gaps = 29/144 (20%) Query: 743 QMAQYGPQQTGPSMSPHP-SPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAY 801 Q Q G + G S H S ++H+G+S ++S TYG SQ+G G Sbjct: 2089 QSTQRGSRTAGRRGSGHSESSDSEVHSGVS---HTHSGHTYGQARSQHGESG-------- 2137 Query: 802 SGVPSASYSGPGPGMGISANNQMHGQ---GPSQPCGAVPLGRMPSAGMQNR--------- 849 SA + G G + + HGQ G S G+ GR S+ ++ Sbjct: 2138 ----SAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEAS 2193 Query: 850 -PFPGNMSSMTPSSPGMSQQGGPG 872 G+ S S G S G G Sbjct: 2194 PTHSGHTHSQAGSRHGQSGSSGHG 2217 Score = 33.1 bits (74), Expect = 3.1 Identities = 44/151 (29%), Positives = 54/151 (35%), Gaps = 23/151 (15%) Query: 1224 FGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEP 1283 FG G S F GQ + S Q Y Q SG+ + G GQ S + Sbjct: 974 FGQHESGSGKSSGF---GQHESRSSQSNYGQHGSGSSQSSGYGQH------GSSSGQTTG 1024 Query: 1284 YGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGM-----YGPPAKRHEGDMYNMQY 1338 +GQ G SG +G H G Q + +H G +G R Y Sbjct: 1025 FGQHRSSSGQYSG---FGQHGSG-SDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHG 1080 Query: 1339 S-SQQQEMYNQYG---GSYSG-PDRRPIQGQ 1364 S S Q Y Q+G G SG RP GQ Sbjct: 1081 SGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQ 1111 Score = 32.0 bits (71), Expect = 6.8 Identities = 48/178 (26%), Positives = 57/178 (32%), Gaps = 33/178 (18%) Query: 1246 SSMQDMYNQ--SPSGAMSNLGM-----GQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQP 1298 SS Y Q S SG S G GQ F S + +GQ G G SG Sbjct: 700 SSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSG-- 757 Query: 1299 PYGGHQPGLYPQQPNYKRHMDGM-----YGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSY 1353 +G H+ Q +Y +H G YG R S Q + QYG Sbjct: 758 -FGQHES--RSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGS 814 Query: 1354 ----------SGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEG 1401 SG + GQ+ SR GQ HG G Q SS G Sbjct: 815 GQSAGFGQHGSGSGQSSGFGQHE---SRSHQSSYGQ---HGSGSSQSSGYGQHGSSSG 866 Score = 32.0 bits (71), Expect = 6.8 Identities = 49/196 (25%), Positives = 63/196 (32%), Gaps = 44/196 (22%) Query: 1241 GQMPNSSMQDMYNQSPSGAMSNLGMGQR-----QQFPYG---------------ASYDRR 1280 GQ + S Q Y Q SG+ + G GQ Q F +G S + Sbjct: 911 GQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQ 970 Query: 1281 HEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGM-----YGPPAKRHEGDMYN 1335 +GQ G G SG +G H+ Q NY +H G YG G Sbjct: 971 SSGFGQHESGSGKSSG---FGQHES--RSSQSNYGQHGSGSSQSSGYGQHGS-SSGQTTG 1024 Query: 1336 MQYSSQQQEMYNQYGGSYSGPDRRPIQGQ----------YPYPYSRERMQGPGQIQTHGI 1385 Y+ +G SG D+ GQ + SR R GQ HG Sbjct: 1025 FGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQ---HGS 1081 Query: 1386 PPQMMGGPLQSSSSEG 1401 G Q S+ G Sbjct: 1082 GSSQSSGYGQHGSNSG 1097 >gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma) [Homo sapiens] Length = 526 Score = 91.3 bits (225), Expect = 1e-17 Identities = 95/314 (30%), Positives = 120/314 (38%), Gaps = 79/314 (25%) Query: 58 QQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG 117 Q QQ Q QQ S + G G + +G ++++ G Q+ P G Sbjct: 23 QGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSS--------YSSYGQSQNTGYGTQSTPQG 74 Query: 118 PPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYG 177 G + G+ + +PG G QQP + G YG Sbjct: 75 YGSTGGYGSSQSSQSSYGQQSS----YPGYG----QQPAPSSTSGS------------YG 114 Query: 178 SAAPASGGPGGRAGPCFDQ--HGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNS 235 S++ +S ++G Q +GGQQ + G S +P Q GY Sbjct: 115 SSSQSSSYGQPQSGSYSQQPSYGGQQQ------------SYGQQQSYNPPQ----GY--G 156 Query: 236 QCNHYPGYSRPGAGGGGGGGGG----------GGGGSGGGGG----GGGAGAGGAGAGAV 281 Q N Y S GGGGGGGGG GGGSGGG G GG G+GG G Sbjct: 157 QQNQYNSSS---GGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDR 213 Query: 282 AAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAA 341 + GGGGGGGY SS GY PR +GGG G GG G GS Sbjct: 214 GGRGRGGSGGGGGGGGGGYNRSSGGY----EPRGRGGG-RGGRGGMG---------GSDR 259 Query: 342 GGFQRFAGQNQHPS 355 GGF +F G S Sbjct: 260 GGFNKFGGPRDQGS 273 Score = 53.1 bits (126), Expect = 3e-06 Identities = 45/131 (34%), Positives = 45/131 (34%), Gaps = 24/131 (18%) Query: 238 NHYPGYSRPGAGGGG--GGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAA----------- 284 N G R G G GG G GG GGGGSGGGG GG GG G G A Sbjct: 376 NRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCEN 435 Query: 285 --------AAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMG---PGGGGAASLS 333 A G GGG GGS G R GG G GG Sbjct: 436 MNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFR 495 Query: 334 KAAAGSAAGGF 344 G GGF Sbjct: 496 GGRGGGDRGGF 506 Score = 46.6 bits (109), Expect = 3e-04 Identities = 55/203 (27%), Positives = 73/203 (35%), Gaps = 41/203 (20%) Query: 704 SQMPPQPPGSQS--------ESSSHPALSQSPMPQERGFMAGTQRNPQ------------ 743 SQ QP G QS ++S + S S Q + GTQ PQ Sbjct: 26 SQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQ 85 Query: 744 --MAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSN----SSGTY------GPQMSQYGP 791 + YG Q + P P+P + SS Q S+ SG+Y G Q YG Sbjct: 86 SSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQ 145 Query: 792 QGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPF 851 Q +Y+ P Y + S G G G N +GQ S ++ G G N+ Sbjct: 146 QQSYNPPQGYGQQNQYNSSSGGGGGGGGGGN--YGQDQS----SMSSGGGSGGGYGNQDQ 199 Query: 852 PGNMSSMTPSSPGMSQQGGPGMG 874 G S G +GG G G Sbjct: 200 SGGGGS---GGYGQQDRGGRGRG 219 Score = 46.6 bits (109), Expect = 3e-04 Identities = 25/57 (43%), Positives = 28/57 (49%), Gaps = 12/57 (21%) Query: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGG 299 ++R G G GG G GG G GG GGGG G G G +GGGGGGG Sbjct: 375 FNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGG------------FPSGGGGGGG 419 Score = 45.8 bits (107), Expect = 5e-04 Identities = 74/289 (25%), Positives = 91/289 (31%), Gaps = 59/289 (20%) Query: 547 YCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNH 606 Y QQ Q Y + QP SQQ QP S GY ++S G+ ++ Sbjct: 6 YTQQATQSYGAYPTQPGQ---------GYSQQSSQPYGQQSYSGY-SQSTDTSGYGQSSY 55 Query: 607 EDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHA 666 G + GT++T S G SSQ QS+ Q Sbjct: 56 SSY---------------GQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQ------ 94 Query: 667 SPHLSSIPG---GPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQS---ESSSH 720 SS PG P+PS GS+ S P S SQ P QS + S + Sbjct: 95 ----SSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYN 150 Query: 721 PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSG 780 P Q G YG Q+ S GG G + QS G Sbjct: 151 PPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSS------MSSGGGSGGGYGNQDQSGGGG 204 Query: 781 TYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGP 829 + G YG Q R SG G G G G N G P Sbjct: 205 SGG-----YGQQDRGGRGRGGSG-------GGGGGGGGGYNRSSGGYEP 241 Score = 45.8 bits (107), Expect = 5e-04 Identities = 44/143 (30%), Positives = 49/143 (34%), Gaps = 28/143 (19%) Query: 177 GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMD------PLQNSHE 230 G GGP GR G GG G G S G + D +N + Sbjct: 382 GRGGRGRGGPMGRGGY---GGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNF 438 Query: 231 GYPNSQCNHYPGYSRPGAGGGGGGGGGGG-------GGSGGGGGGGGAGAGGAGAGAVAA 283 + N +CN G GGG GG GG GG GG GG G GG G Sbjct: 439 SWRN-ECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGF--- 494 Query: 284 AAAAAAAAAGGGGGGGYGGSSAG 306 GG GGG GG G Sbjct: 495 --------RGGRGGGDRGGFGPG 509 Score = 44.3 bits (103), Expect = 0.001 Identities = 43/155 (27%), Positives = 53/155 (34%), Gaps = 30/155 (19%) Query: 50 QQLNQFQQQQQQQQQQQQQQQQ---QQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKD 106 QQ + QQQ QQQ Q QQ+ ++++ GG GGG G D GG Sbjct: 132 QQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSG 191 Query: 107 SAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGP 166 G Q G G G+ + G G G+ GGGG Sbjct: 192 GGYGNQDQSGGG----------------GSGGYGQQDRGGRGRGGS---------GGGGG 226 Query: 167 AAVPEFNNYYGSAAP--ASGGPGGRAGPCFDQHGG 199 +N G P GG GGR G GG Sbjct: 227 GGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGG 261 Score = 39.7 bits (91), Expect = 0.033 Identities = 61/263 (23%), Positives = 83/263 (31%), Gaps = 56/263 (21%) Query: 173 NNYYGSAAPASGGPGGRAGPCFDQHGGQ---QSPGMGMMHSASAAAAGAPGSMDPLQNSH 229 N+Y A + G + G + Q Q Q G S + G Q+S+ Sbjct: 4 NDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYG--------QSSY 55 Query: 230 EGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGG------GGGGAGAGGAGAGAVAA 283 Y SQ Y S P G GG G G G G A + +G+ + Sbjct: 56 SSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS 115 Query: 284 AAAAAAAAAGGGGG----GGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGS 339 ++ +++ G YGG YG +QQ G G + S G Sbjct: 116 SSQSSSYGQPQSGSYSQQPSYGGQQQSYG-----QQQSYNPPQGYGQQNQYNSSSGGGGG 170 Query: 340 AAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQA 399 GG GQ+Q M S GGS Y + Q Q+ Sbjct: 171 GGGGGNY--GQDQSS-----------------MSSGGGSGGGYGN-----------QDQS 200 Query: 400 AAAGAAAGGQQAAAGMGLGKDMG 422 G+ GQQ G G G G Sbjct: 201 GGGGSGGYGQQDRGGRGRGGSGG 223 Score = 38.1 bits (87), Expect = 0.096 Identities = 46/177 (25%), Positives = 61/177 (34%), Gaps = 25/177 (14%) Query: 1194 NSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYN 1253 N T A G + P G+ + + P+G + G S+ T G +S + Sbjct: 4 NDYTQQATQSYG-AYPTQPGQGYSQQSSQPYG-QQSYSGYSQSTDTSGYGQSSYSSYGQS 61 Query: 1254 QSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQ--YPGQGPP-------------SGQP 1298 Q+ + G YG+S + YGQQ YPG G S Sbjct: 62 QNTGYGTQSTPQGYGSTGGYGSSQSSQSS-YGQQSSYPGYGQQPAPSSTSGSYGSSSQSS 120 Query: 1299 PYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSG 1355 YG Q G Y QQP+Y YG + YN QQ YN G G Sbjct: 121 SYGQPQSGSYSQQPSYGGQQQS-YG------QQQSYNPPQGYGQQNQYNSSSGGGGG 170 Score = 37.4 bits (85), Expect = 0.16 Identities = 31/106 (29%), Positives = 37/106 (34%), Gaps = 46/106 (43%) Query: 257 GGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQ 316 GGG G GG G GG G GG G G +GGGG GG+ Sbjct: 378 GGGNGRGGRGRGGPMGRGGYGGGG-----------SGGGGRGGF---------------- 410 Query: 317 GGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLN 362 P GGG GG Q+ AG + P+ +N Sbjct: 411 -------PSGGGG------------GGGQQRAGDWKCPNPTCENMN 437 Score = 33.5 bits (75), Expect = 2.4 Identities = 37/150 (24%), Positives = 45/150 (30%), Gaps = 23/150 (15%) Query: 474 GSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFW 533 G+ P Q S YG Y G + Y Q Q++G T Sbjct: 15 GAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQST--- 71 Query: 534 LMPPQYGQQG--------VSGYCQQGQQPYYSQQPQPPHL--------PPQAQYLPSQSQ 577 P YG G S Y QQ P Y QQP P + P Sbjct: 72 --PQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGS 129 Query: 578 QRYQPQQDMSQEGYGTRS--QPPLAPGKPN 605 QP Q+ YG + PP G+ N Sbjct: 130 YSQQPSYGGQQQSYGQQQSYNPPQGYGQQN 159 Score = 32.3 bits (72), Expect = 5.2 Identities = 30/119 (25%), Positives = 46/119 (38%), Gaps = 5/119 (4%) Query: 826 GQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQ 885 GQG SQ + P G+ +G + SS G SQ G G + + Sbjct: 22 GQGYSQQ-SSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGT----QSTPQGYG 76 Query: 886 EAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPA 944 ++ S+ +Q S+PG Q +S+S + SSS Q+ YS P+ Sbjct: 77 STGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPS 135 Score = 32.0 bits (71), Expect = 6.8 Identities = 45/190 (23%), Positives = 57/190 (30%), Gaps = 19/190 (10%) Query: 337 AGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQ 396 A + G + GQ + P Q + S + G YSS Q Sbjct: 10 ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYG---------Q 60 Query: 397 SQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQ 456 SQ G + Q + G G +Q + QQ S+P + S Sbjct: 61 SQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYG-------QQSSYPGYGQQPAPSSTSGSY 113 Query: 457 GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPP---GPQRYPIGIQGRTPGAMA 513 GS +PQ P QQ S SY PP G Q G G Sbjct: 114 GSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGG 173 Query: 514 GMQYPQQQDS 523 G Y Q Q S Sbjct: 174 GGNYGQDQSS 183 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 90.9 bits (224), Expect = 1e-17 Identities = 212/915 (23%), Positives = 314/915 (34%), Gaps = 131/915 (14%) Query: 104 AKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQ-QPPVAVPGG 162 AK AA P LL+ PP PA R LGA G + P+A G Sbjct: 8 AKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRV----LGAAGAVGRKPLAERAG 63 Query: 163 GGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSM 222 G G A +PE +AP RAGP +S G + AS A G Sbjct: 64 GIGGATIPE-------SAP-------RAGPT-------RSAGTSSRNPASRPPASGRGER 102 Query: 223 DPLQNSHEGYPNSQCNHYPGYSRPGAGGGGG-----------GGGGGGGGSGGGGGGGGA 271 P + P S G +RPG G G G G Sbjct: 103 APPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARR 162 Query: 272 GAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAAS 331 G G + A A + AAG G SA PR G S Sbjct: 163 DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSA------RPRPPTEGPRKSVSSASEHS 216 Query: 332 LSKAAAG-----SAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPS 386 ++ + SA GG QR A ++ S ATP + + PS ++P P Sbjct: 217 TTEPSPAARRRPSAGGGLQRPASRSLS-SSATPLSSPARSGPSARGTPRAPAHPSQPKPK 275 Query: 387 A----PPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPA 442 PP + P+ AA A G +++ + A + A P A S Sbjct: 276 GLQALRPPQVTPPRKDAAPAL----GPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLT 331 Query: 443 MSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGG-------SYGPP 495 TP P S +P P L + S P + P Q++ G S+ P Sbjct: 332 CQLATPLPLAPPSPSAP--------PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS 383 Query: 496 GPQRYPIGIQGRTPGAMA--GMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQ 553 P + P A+A +Q P + PP S Sbjct: 384 PPLSPLATPPPQAPPALALPPLQAPPSPPAS-----------PPLSPLATPSPQAPNALA 432 Query: 554 PYYSQQP--QPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLA--PGKPNHEDL 609 + Q P PP P QA + P S P + + + PPL P P + Sbjct: 433 VHLLQAPFSPPPSPPVQAPFSPPASPP-VSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 491 Query: 610 NLIQQERPSSLPDLSGSIDDL----PTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPH 665 + P + P L+ L P A + + A S + S P Q+PFSP Sbjct: 492 SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPA----SFPGQAPFSPS 547 Query: 666 ASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESS-SHPALS 724 AS +S + +P P PV + P SP + P Q P +PP ++S S P L+ Sbjct: 548 ASLPMSPL---ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLT 604 Query: 725 QSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGP 784 + P G R+P GP G S S +P + G S + ++ + P Sbjct: 605 LALAP---GPPPPPSRSPSSTLSGPDLAGHSSSATSTP--EELRGYDSGPEGGAAASPPP 659 Query: 785 --QMSQYGPQGNYSRPP----AYSGVPSASY-----SGPGPGMGISANNQMHGQGPSQPC 833 +++ P +SR P A+ G P A +GPG G+ + G + P Sbjct: 660 DAELAACHPAA-WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPA 718 Query: 834 -GAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVM 892 GA+ G P + G + + SP ++ G +G +V + + ++ Sbjct: 719 PGALDPGPSPGTS-GGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHL--LSRTLL 775 Query: 893 QAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAAS 952 AAA A G PG + G + + ++L + + ++ + ++ S AS Sbjct: 776 LAAAEGAAGGSGGGPGGAEGGGVTGGA--------RAALSDAELGRWAELLSPLDESRAS 827 Query: 953 VGLADMMSPGESKLP 967 + SP + P Sbjct: 828 ITSVTSFSPDDVASP 842 Score = 84.7 bits (208), Expect = 9e-16 Identities = 161/739 (21%), Positives = 236/739 (31%), Gaps = 120/739 (16%) Query: 327 GGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPS 386 G A ++ + AGG P A PT + +S +P R E +P Sbjct: 48 GAAGAVGRKPLAERAGGIGGATIPESAPR-AGPTRSAGTSSRNPASRPPASGRGE-RAPP 105 Query: 387 APPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMG-----AQYAAASPAWAAAQQRSHP 441 A P S A+G G G+ + + A A A +A +R Sbjct: 106 AKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTS 165 Query: 442 AMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYP 501 +PGTP P M R + + + RP + +P P S P Sbjct: 166 GPTPGTPSPAMARRSRAAGTEVGLPRP-----APSARPRPPTEGPRKSVSSASEHSTTEP 220 Query: 502 IGIQGRTPGAMAGMQYPQQQD-SGDATWKETFWLMPPQYGQQGVSGYCQQG--QQPYYSQ 558 R P A G+Q P + S AT SG +G + P + Sbjct: 221 SPAARRRPSAGGGLQRPASRSLSSSAT----------PLSSPARSGPSARGTPRAPAHPS 270 Query: 559 QPQPPHL---------PPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDL 609 QP+P L PP+ P+ P S PP P P+ L Sbjct: 271 QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSL 330 Query: 610 NLIQQERPSSL----PDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPH 665 Q P L P S+ LP+ S A ++ GS + Q S P SP Sbjct: 331 TC-QLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPL 389 Query: 666 ASPH--------LSSIPGGPSP--SPVGSPVGSNQSRS----------GPISPASIPGSQ 705 A+P L + PSP SP SP+ + ++ P SP P Q Sbjct: 390 ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 449 Query: 706 MPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQ 765 P PP S S S SQ+P + P P T P +P P Sbjct: 450 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 509 Query: 766 MHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMH 825 + Q+++ PQ PPA + P + P Sbjct: 510 L------------------QLAKPPPQA----PPALATPPLQALPSPPA--------SFP 539 Query: 826 GQGPSQPCGAVPLGRMPSAGMQNRPF---------PGNMSSMTPSSPGMSQQGGP----- 871 GQ P P ++P+ + + Q P P +S T +P GP Sbjct: 540 GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS 599 Query: 872 --------GMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMN---QSGLMASSSP 920 GPP P + + + ++SA S G + + G AS P Sbjct: 600 GPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP 659 Query: 921 YSQ-PMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESK-LPLPLKADGKEEG 978 ++ + ++ APP A + A + PG + L + +G E Sbjct: 660 DAELAACHPAAWSRGPAPPL----AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESA 715 Query: 979 TPQPESKSKKSSSSTTTGE 997 TP P + S T+ G+ Sbjct: 716 TPAPGALDPGPSPGTSGGK 734 Score = 44.3 bits (103), Expect = 0.001 Identities = 54/187 (28%), Positives = 71/187 (37%), Gaps = 30/187 (16%) Query: 1414 PYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQP 1473 P P Q P P +PP + T P Q P P MS SA+ P Sbjct: 442 PPPSPPVQAPFSPPASPPV-SPSATPPSQAPPSLAAPPLQVPPSPPASPP-MSPSATPPP 499 Query: 1474 ITRPP---------QPSYQTPPSLPNHISRA-PSP-ASFQRSLENRMSPSKSPFLPSMKM 1522 PP +P Q PP+L +A PSP ASF P ++PF PS + Sbjct: 500 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASF---------PGQAPFSPSASL 550 Query: 1523 QKVMPTVPTSQVTGPPPQPPPI-RREITFPPGSVEASQPVLKQRRKITSKDIVTPEAWRV 1581 P S + PPPQ PP+ + P S AS + RR T + R+ Sbjct: 551 -------PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 603 Query: 1582 MMSLKSG 1588 ++L G Sbjct: 604 TLALAPG 610 Score = 43.9 bits (102), Expect = 0.002 Identities = 64/257 (24%), Positives = 80/257 (31%), Gaps = 86/257 (33%) Query: 90 PQPGPDMEQPQHGGAKDSAAGGQADPP-----------GPPLLSKPGDEDDAPPKM---- 134 P PGPD G + + A PP GP L P ++ Sbjct: 590 PTPGPDTSV---SGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD 646 Query: 135 GEPAGGRYE-----------HPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPAS 183 P GG HP + G PP+A G G P P PA+ Sbjct: 647 SGPEGGAAASPPPDAELAACHPAAWSRGPA-PPLAFRGAPGAPLPWP----------PAT 695 Query: 184 GGPGGRAGPC--FDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYP 241 G PG G C ++ G + +A APG++DP + Sbjct: 696 G-PGSADGLCTIYETEGPE-------------SATPAPGALDPGPS-------------- 727 Query: 242 GYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGA------------GAVAAAAAAAA 289 PG GG G G G S G GA + AAA AA Sbjct: 728 ----PGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAA 783 Query: 290 AAAGGGGGGGYGGSSAG 306 +GGG GG GG G Sbjct: 784 GGSGGGPGGAEGGGVTG 800 Score = 39.7 bits (91), Expect = 0.033 Identities = 95/480 (19%), Positives = 149/480 (31%), Gaps = 62/480 (12%) Query: 1121 QPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPT-PASTPHGQMTPMQGGRSSTISVH 1179 +PP P +L+ + G +AE G + T P S P T G S + Sbjct: 34 RPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASR 93 Query: 1180 DPFSDVSDSSFPKRNSM---TPNAPYQQGMSMPDVMGRMPYEPNKDPF---GGMRKVPGS 1233 P S + + P +N+ + G + P +G+ + + G + P Sbjct: 94 PPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKR 153 Query: 1234 SEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGP 1293 S ++ G ++S SP+ A + G P A R P +GP Sbjct: 154 SA--LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT------EGP 205 Query: 1294 PSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSY 1353 H + G PA R ++ S+ + G S Sbjct: 206 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR------SLSSSATPLSSPARSGPSA 259 Query: 1354 SGPDRRPIQGQYPYPYSRERMQGP-------------GQIQTHGIPPQMMGGPLQSSSSE 1400 G R P P P + ++ P G + + + LQS + Sbjct: 260 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPP 319 Query: 1401 G----PQQNMWAARNDMPYPYQNRQGPGGPT-----QAPPYPGMNRTDDMMVPDQRINHE 1451 P + + P P P+ P P T + P + H Sbjct: 320 TLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHS 379 Query: 1452 ---SQWPSHVSQRQPYMSSSASMQPITRPPQP------------SYQTPPSLPNHISRAP 1496 S S ++ P + ++ P+ PP P S Q P +L H+ +AP Sbjct: 380 FLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 439 Query: 1497 SPASFQRSLENRMSPSKS-PFLPSMKMQKVMP---TVPTSQVTGPPPQPPPIRREITFPP 1552 ++ SP S P PS P P QV PP PP+ T PP Sbjct: 440 FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 499 Score = 39.3 bits (90), Expect = 0.043 Identities = 50/198 (25%), Positives = 63/198 (31%), Gaps = 14/198 (7%) Query: 92 PGPDMEQPQHGGAKDSAA-------GGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEH 144 P + P G SA G + P G S P D + A A R Sbjct: 619 PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA--CHPAAWSRGPA 676 Query: 145 PGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRA---GPCFDQHGGQQ 201 P L G P+ P G P + Y + P S P A GP GG+ Sbjct: 677 PPLAFRGAPGAPLPWPPATG-PGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKA 735 Query: 202 SPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGG 261 + G G S+ + G + PL + + GG GGG GG Sbjct: 736 AAGAGAGASSRSPKQARLGEL-PLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAE 794 Query: 262 SGGGGGGGGAGAGGAGAG 279 GG GG A A G Sbjct: 795 GGGVTGGARAALSDAELG 812 Score = 33.9 bits (76), Expect = 1.8 Identities = 36/126 (28%), Positives = 47/126 (37%), Gaps = 16/126 (12%) Query: 85 AGGGAPQPGPDMEQPQHGGAKDS-AAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYE 143 AG GP P A+ S AAG + P P ++P + P K A E Sbjct: 158 AGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSAS---E 214 Query: 144 HPGLGALGTQQPPVAV---PGGGGG---PAAVPEFNNYYGSAAPASGGPGGRAGPCFDQH 197 H T +P A P GGG PA+ ++ ++PA GP R P H Sbjct: 215 H------STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268 Query: 198 GGQQSP 203 Q P Sbjct: 269 PSQPKP 274 Score = 33.5 bits (75), Expect = 2.4 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 15/82 (18%) Query: 1104 PPPEVFSTGDTKKQPKLQ-PPSPANSGSLQGPQTPQSTGSN--------SMAEVPGDLKP 1154 PPP+ P LQ PPSP S +LQ P+ P + G + ++A PG P Sbjct: 558 PPPQA---PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG--PP 612 Query: 1155 PTPASTPHGQMT-PMQGGRSST 1175 P P+ +P ++ P G SS+ Sbjct: 613 PPPSRSPSSTLSGPDLAGHSSS 634 Score = 32.7 bits (73), Expect = 4.0 Identities = 46/230 (20%), Positives = 81/230 (35%), Gaps = 28/230 (12%) Query: 1351 GSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAAR 1410 G + P + G P PG + G+ + ++E P+++ +A Sbjct: 100 GERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAG 159 Query: 1411 NDMPYPYQNRQGPGGPTQAPPYPGMNRTD-----DMMVPDQRINHESQWPSHVSQRQPYM 1465 R+ GPT P P M R ++ +P + + P+ P Sbjct: 160 A--------RRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE----GPRK 207 Query: 1466 SSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKS----------P 1515 S S++ + T P P+ + PS + R P+ S S SP++S P Sbjct: 208 SVSSASEHSTTEPSPAARRRPSAGGGLQR-PASRSLSSSATPLSSPARSGPSARGTPRAP 266 Query: 1516 FLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQR 1565 PS K + + QVT P P ++ P + + L+ + Sbjct: 267 AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQ 316 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 90.5 bits (223), Expect = 2e-17 Identities = 208/836 (24%), Positives = 273/836 (32%), Gaps = 126/836 (15%) Query: 111 GQADPPGPPLLS----KPGDEDDAPPKMGEPAG-GRYEHPGLGALGTQQPPVAVPGGGGG 165 G PPGPP ++ +PG + + P+ GEP G+ +PG L Q + PG G Sbjct: 688 GPPGPPGPPGVTGMDGQPGPKGNVGPQ-GEPGPPGQQGNPGAQGLPGPQGAIGPPGEKG- 745 Query: 166 PAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPG----- 220 P P G+ P G PG P + GGQ PG G PG Sbjct: 746 PLGKPGLPGMPGADGPP-GHPGKEGPP--GEKGGQGPPG-------PQGPIGYPGPRGVK 795 Query: 221 SMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGA 280 D ++ + +PG+ G G G G G G G G GG Sbjct: 796 GADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDP 855 Query: 281 VAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSA 340 G G GY G G + P G G G + G Sbjct: 856 GPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPT 915 Query: 341 AGGFQRFAGQNQHPSGAT----PTLNQLLTSPSPMMRSYGGSYPE----YSSPSAPPPPP 392 +R P G T P N P+ G + P+ + P PP PP Sbjct: 916 GPRGER------GPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPP 969 Query: 393 SQPQSQAAAAGAAAGGQQAAAGM-GLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPG-- 449 + G Q G G +G Q +R HP PG PG Sbjct: 970 GKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETG--PMGERGHPG-PPGPPGEQ 1026 Query: 450 --PTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYG---------PPGP- 497 P + +G+ DP P G + P P G+ G PPGP Sbjct: 1027 GLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPA 1086 Query: 498 ----QRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQ 553 +R P G G P + G PQ G A K P + G QG +G + G Q Sbjct: 1087 GSPGERGPAGAAG--PIGIPGRPGPQGPP-GPAGEKGA----PGEKGPQGPAG--RDGLQ 1137 Query: 554 -PYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQP-------PLAPGKPN 605 P P P PP + +P Q S+ G + P P+ P+ Sbjct: 1138 GPVGLPGPAGPVGPPGED---GDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPS 1194 Query: 606 HED--------LNLIQQ---ERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQ 654 D L Q E P P G P G + L G T G Sbjct: 1195 GADGEPGPRGQQGLFGQKGDEGPRGFPGPPG-----PVGLQG-LPGPPGEKGETGDVGQM 1248 Query: 655 SNPAQ-SPFSPHASPHLSSIPGGPSPSPVGSPVG-SNQSRSGPISPASIPGSQMPPQPPG 712 P P P +P P GP P +G+P + G +PG PP P G Sbjct: 1249 GPPGPPGPRGPSGAPGADG-PQGP-PGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKG 1306 Query: 713 SQSE--SSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPS-----PGGQ 765 + E S + P P+ G + +P + P GP P P+ PG + Sbjct: 1307 ERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGF-PGDPGPPGEPGPAGQDGPPGDK 1365 Query: 766 MHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPS-ASYSGPGPGMGISANNQM 824 G + +G+ GP + GP G PP G P A G G + Sbjct: 1366 GDDG-----EPGQTGSPGP-TGEPGPSG----PPGKRGPPGPAGPEGRQGEKGAKGEAGL 1415 Query: 825 HG----QGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPP 876 G GP P GA G+ G++ P P + P SPG GP MGPP Sbjct: 1416 EGPPGKTGPIGPQGAP--GKPGPDGLRGIPGPVGEQGL-PGSPGPDGPPGP-MGPP 1467 Score = 90.1 bits (222), Expect = 2e-17 Identities = 201/802 (25%), Positives = 251/802 (31%), Gaps = 155/802 (19%) Query: 111 GQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPP--VAVPGGGGGPA- 167 G+ G P + +PG + PP PAG G GT P V PG G P Sbjct: 450 GEKGQKGEPAIIEPGMLIEGPPGPEGPAGLP------GPPGTMGPTGQVGDPGERGPPGR 503 Query: 168 -AVPEFNNYYGSAA-----PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGS 221 +P + G P G GG AG Q+S ++ A A G G Sbjct: 504 PGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGP 563 Query: 222 MDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAV 281 M PG P GG G G G G G G G G Sbjct: 564 MG-------------LTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPG--- 607 Query: 282 AAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAA 341 A + A G G G G G+ P ++G GP G G Sbjct: 608 RRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSG---------PPGPPG 658 Query: 342 GGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAA 401 +R P G L P P R G P PP PP P Sbjct: 659 DDGERGDDGEVGPRG-------LPGEPGP--RGLLG-------PKGPPGPPGPP------ 696 Query: 402 AGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMD 461 GQ G ++G Q P Q+ +P + G PGP + G P + Sbjct: 697 GVTGMDGQPGPKG-----NVGPQGEPGPPG-----QQGNPG-AQGLPGPQ--GAIGPPGE 743 Query: 462 PMVMKRPQLYGM--GSNPHSQPQQSSPYPG--GSYGPPGPQRYPIGIQGRTPGAMAGMQY 517 + +P L GM P P + P PG G GPPGPQ PIG G P + G Sbjct: 744 KGPLGKPGLPGMPGADGPPGHPGKEGP-PGEKGGQGPPGPQG-PIGYPG--PRGVKGA-- 797 Query: 518 PQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQ 577 G K T + G+ G G+ +G + + P+ + P + Sbjct: 798 -----DGIRGLKGT----KGEKGEDGFPGF--KGDMGIKGDRGEIGPPGPRGEDGPEGPK 846 Query: 578 QRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEAT 637 R P D G PP GK +P L G Sbjct: 847 GRGGPNGDPGPLG------PPGEKGK--------------LGVPGLPGYPGRQGPKGSIG 886 Query: 638 LSSAVSASGSTSSQGDQSNPA----QSPFSPHASPHLSSIPGGPSP-------SPVGSPV 686 A+G +G P + P P I G P P P G P Sbjct: 887 FPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPP- 945 Query: 687 GSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQ 746 + +GP P PG + PP PPG HP E GF T Sbjct: 946 -GERGPNGPQGPTGFPGPKGPPGPPGKDG-LPGHPG-----QRGETGFQGKTGPPGPPGV 998 Query: 747 YGPQ----QTGP-SMSPHPSPGGQM-HAGISSFQQSNSSGTYGPQMSQYGPQG--NYSRP 798 GPQ +TGP HP P G G+ + GT G GP G P Sbjct: 999 VGPQGPTGETGPMGERGHPGPPGPPGEQGLPGL--AGKEGTKGDP----GPAGLPGKDGP 1052 Query: 799 PAYSGVP-SASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSS 857 P G P GP +G+ N GP P G+ P R P+ PG Sbjct: 1053 PGLRGFPGDRGLPGPVGALGLKGNE--GPPGPPGPAGS-PGERGPAGAAGPIGIPGRPGP 1109 Query: 858 MTPSSPGMSQQGGPG-MGPPMP 878 P P ++G PG GP P Sbjct: 1110 QGPPGPA-GEKGAPGEKGPQGP 1130 Score = 87.8 bits (216), Expect = 1e-16 Identities = 237/975 (24%), Positives = 301/975 (30%), Gaps = 169/975 (17%) Query: 58 QQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG 117 Q+ Q Q QQ + + L G G PG + + G G PPG Sbjct: 542 QESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPG 601 Query: 118 PPLLSKPG-------DEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVP 170 P KPG D P P G R GL L ++ P G GP P Sbjct: 602 P--AGKPGRRGRAGSDGARGMPGQTGPKGDR-GFDGLAGLPGEKGHRGDP-GPSGPPGPP 657 Query: 171 EFNNYYGS-------AAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMD 223 + G P GP G GP G PG+ M G G++ Sbjct: 658 GDDGERGDDGEVGPRGLPGEPGPRGLLGP-KGPPGPPGPPGVTGMD----GQPGPKGNVG 712 Query: 224 PLQNSHEGYPNSQCNHYPGYSRPGAGG--GGGGGGGGGGGSGGGGGGGGAGAGGAGAGAV 281 P G P Q N PGA G G G G G G G G G GA Sbjct: 713 P--QGEPGPPGQQGN-------PGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGAD---- 759 Query: 282 AAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGP----GGGGAASLSKAAA 337 G G G G G G P QG GP G G L Sbjct: 760 --------GPPGHPGKEGPPGEKGGQG---PPGPQGPIGYPGPRGVKGADGIRGLKGTKG 808 Query: 338 GSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQS 397 GF F G G + + P P P+ P P P Sbjct: 809 EKGEDGFPGFKGD----MGIKGDRGE-IGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGE 863 Query: 398 QAAAAGAAAGGQQAAAGM-GLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQ 456 + G+ G+ G G + + P + A +PG PGP R Q Sbjct: 864 K---------GKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGP---RGQ 911 Query: 457 GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQ 516 P P + P+ G+ P + P GPPG +R P G QG P G + Sbjct: 912 RGPTGPRGERGPR--GITGKPGPKGNSGGDGPA---GPPG-ERGPNGPQG--PTGFPGPK 963 Query: 517 YPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQS 576 P D +P GQ+G +G+ QG+ + P PP + Sbjct: 964 GPPGPPGKDG--------LPGHPGQRGETGF--QGK----TGPPGPPGV----------- 998 Query: 577 QQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEA 636 PQ + G P PG P + LP L+G A Sbjct: 999 ---VGPQGPTGETGPMGERGHPGPPGPPGEQ-----------GLPGLAGKEGTKGDPGPA 1044 Query: 637 TLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPS-PSPVGSPVGSNQSRSGP 695 L G GD+ P P + L G P P P GSP + +G Sbjct: 1045 GLPGKDGPPGLRGFPGDRGLP-----GPVGALGLKGNEGPPGPPGPAGSP--GERGPAGA 1097 Query: 696 ISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYG-PQQTGP 754 P IPG P PPG E + P E+G R+ G P GP Sbjct: 1098 AGPIGIPGRPGPQGPPGPAGEKGA---------PGEKGPQGPAGRDGLQGPVGLPGPAGP 1148 Query: 755 SMSPHPSPGGQMHAGISSFQQSNSSGTYGPQ--MSQYGPQGNYSRPPAYSGVPSASYSGP 812 + P G + G Q S G G Q GPQG +P PS + P Sbjct: 1149 -VGPPGEDGDKGEIGEPG--QKGSKGDKGEQGPPGPTGPQGPIGQPG-----PSGADGEP 1200 Query: 813 GPGMGISANNQMHGQGP---SQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSP--GMSQ 867 GP Q +GP P G V L +P + + G++ M P P Sbjct: 1201 GPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGE-KGETGDVGQMGPPGPPGPRGP 1259 Query: 868 QGGPG----MGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQ 923 G PG GPP N A +A G + G S P Sbjct: 1260 SGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGP--- 1316 Query: 924 PMNNSSSLMNTQAPPYSMAPAMVNSSAASVGL-ADMMSPGESKLPLPLKADGKEEGTPQP 982 + ++ + PP P S VG D PGE P P DG G Sbjct: 1317 --SGAAGPPGPKGPPGDDGP---KGSPGPVGFPGDPGPPGE---PGPAGQDG-PPGDKGD 1367 Query: 983 ESKSKKSSSSTTTGE 997 + + ++ S TGE Sbjct: 1368 DGEPGQTGSPGPTGE 1382 Score = 85.9 bits (211), Expect = 4e-16 Identities = 179/702 (25%), Positives = 215/702 (30%), Gaps = 132/702 (18%) Query: 83 GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPP----LLSKPGDEDDA-------- 130 G +GG P GP E+ +G + G PPGPP L PG + Sbjct: 934 GNSGGDGPA-GPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP 992 Query: 131 --PPKMGEPAGGRYEHPGLGALGTQQPP-----VAVPG--------GGGGPAAVPEFNNY 175 PP + P G E +G G PP +PG G GPA +P Sbjct: 993 PGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLP----- 1047 Query: 176 YGSAAPAS--GGPGGRAGP----CFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSH 229 G P G PG R P G + PG AG+PG P + Sbjct: 1048 -GKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPG-------PPGPAGSPGERGPAGAAG 1099 Query: 230 E-GYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAA 288 G P PG P G G G G G G G G G A Sbjct: 1100 PIGIPGR-----PGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGE 1154 Query: 289 AAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMG-PGGGGAASLSKAAAGSAAGGFQRF 347 G G G GS G P G +G PG GA G + Sbjct: 1155 DGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGD 1214 Query: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407 G P P Q L P P + G + PP P P+ + A GA G Sbjct: 1215 EGPRGFPGPPGPVGLQGLPGP-PGEKGETGDVGQMG-----PPGPPGPRGPSGAPGAD-G 1267 Query: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAM--SPGTPGPTMGRSQGSPMDPMVM 465 Q G+G + GA P A P + G PGP R + P Sbjct: 1268 PQGPPGGIG---NPGAVGEKGEPGEAG-----EPGLPGEGGPPGPKGERGEKGESGPSGA 1319 Query: 466 KRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGD 525 P G P + SP P G G PGP P AG P D Sbjct: 1320 AGPP--GPKGPPGDDGPKGSPGPVGFPGDPGPPGEP---------GPAGQDGPPGDKGDD 1368 Query: 526 ATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQD 585 P Q G G +G P P P P Q + + Sbjct: 1369 GE--------PGQTGSPGPTGEPGPSGPPGKRGPPGPAG--------PEGRQGEKGAKGE 1412 Query: 586 MSQEGYGTRSQP---PLAPGKPNHEDLNLI-----QQERPSS--------------LPDL 623 EG ++ P APGKP + L I +Q P S LP L Sbjct: 1413 AGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGL 1472 Query: 624 SGSIDDLPTGTEAT--LSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGP--SP 679 G D P G + L + G +GD+ P S + P GP P Sbjct: 1473 KG--DSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPP 1530 Query: 680 SPVG-----SPVGSNQSRSGPISPASIPGSQMPPQPPGSQSE 716 P G P G+ S SGP P G PP PPG E Sbjct: 1531 GPPGLPGPPGPKGAKGS-SGPTGPKGEAGHPGPPGPPGPPGE 1571 Score = 69.7 bits (169), Expect = 3e-11 Identities = 144/579 (24%), Positives = 182/579 (31%), Gaps = 81/579 (13%) Query: 76 ISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMG 135 + N G G A PG E+ G A G+ P GPP P E AP + G Sbjct: 1073 LKGNEGPPGPPGPAGSPG---ERGPAGAAGPIGIPGRPGPQGPP---GPAGEKGAPGEKG 1126 Query: 136 E--PAGGRYEHPGL-GALGTQQP--PVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRA 190 PAG GL G +G P PV PG G + E GP G Sbjct: 1127 PQGPAG----RDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPT 1182 Query: 191 GPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPL----QNSHEGYPNSQCNHYPGYSRP 246 GP G PG + A G PG Q EG P +PG P Sbjct: 1183 GP----QGPIGQPG-------PSGADGEPGPRGQQGLFGQKGDEG-PRG----FPGPPGP 1226 Query: 247 GAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAG 306 G G G G +G G G G G + A A GG G G G Sbjct: 1227 VGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGE 1286 Query: 307 YGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLT 366 G P G G GP G +G+A + + P G Sbjct: 1287 PGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKG---------- 1336 Query: 367 SPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAG-MGLGKDMGAQY 425 SP P+ +P P P P Q GQ + G G G Sbjct: 1337 SPGPV------GFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPG 1390 Query: 426 AAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPM-VMKRPQLYGMGSNPHSQPQQS 484 P A + R + G G + P+ P +P G+ P +Q Sbjct: 1391 KRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQG 1450 Query: 485 SPYPGGSYGPPGPQRYP--IGIQGRT--------PGAMAGMQYP-QQQDSGDATWKETFW 533 P G GPPGP P G++G + PG + + P +Q + GD Sbjct: 1451 LPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQG 1510 Query: 534 LMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQD--MSQEGY 591 P+ G+QG++G P P PP LP + +G Sbjct: 1511 SSGPK-GEQGITG-------------PSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGE 1556 Query: 592 GTRSQPPLAPGKPNHEDLNL-IQQERPSSLPDLSGSIDD 629 PP PG P L IQ R D S +DD Sbjct: 1557 AGHPGPPGPPGPPGEVIQPLPIQASRTRRNIDASQLLDD 1595 Score = 32.3 bits (72), Expect = 5.2 Identities = 47/213 (22%), Positives = 69/213 (32%), Gaps = 55/213 (25%) Query: 1112 GDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGG 1171 G+T Q K PP P + GPQ P TG G PP P P Q P G Sbjct: 982 GETGFQGKTGPPGPPG---VVGPQGP--TGETGPMGERGHPGPPGP---PGEQGLPGLAG 1033 Query: 1172 RSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVP 1231 + T D + P ++ + +P +G + + N+ P P Sbjct: 1034 KEGTKG------DPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGP-------P 1080 Query: 1232 GSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQ 1291 G P + G+ + P+GA +G+ PG+ Sbjct: 1081 GPPGPAGSPGE-----------RGPAGAAGPIGI-----------------------PGR 1106 Query: 1292 GPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGP 1324 P G P G + + P DG+ GP Sbjct: 1107 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGP 1139 >gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] Length = 1690 Score = 89.0 bits (219), Expect = 5e-17 Identities = 213/863 (24%), Positives = 252/863 (29%), Gaps = 183/863 (21%) Query: 84 GAGGGAPQPGP-----DMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPA 138 G G A PGP DM P GG K S+ G PPGPP + P G+PA Sbjct: 710 GTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVG---PPGPPGSPGVNGQKGIP---GDPA 763 Query: 139 GGRYEHPG---LGALGTQQPPVAVPG--GGGGPAAVPEFNNYYGSAAPASGGPGGRAGPC 193 G PG L + + P PG G GPA +P F G P GR G Sbjct: 764 FGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKG--------PKGREG-- 813 Query: 194 FDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGG 253 H G HS A G PG Q GYP S G +PG G G Sbjct: 814 ---HAGFPGVPGPPGHSCERGAPGIPG-----QPGLPGYPGSP-GAPGGKGQPGDVGPPG 864 Query: 254 GGGGGG-----GGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYG 308 G G G G G G G G G G G+ G G Sbjct: 865 PAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPG 924 Query: 309 VLSSPRQQGG----GMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQL 364 P +G GM PG G A G Q P P + Sbjct: 925 AEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDG 984 Query: 365 LTSP-----SPMMRSYGGSYPEYSSPS------------APPPPPSQPQSQAAAAGAAAG 407 +P M+ G Y P PP PP P S Sbjct: 985 FPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGST--------- 1035 Query: 408 GQQAAAGM-GLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMK 466 G + G GL D G + P ++ P + G P G Sbjct: 1036 GLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGP------------ 1083 Query: 467 RPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDA 526 P + + SP G +G G Q P GIQG P G P Sbjct: 1084 ----------PGPKGEPGSPGCPGHFGASGEQGLP-GIQG--PRGSPGRPGPPGSSGPPG 1130 Query: 527 TWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDM 586 P +G G+ G QP P P L Q D Sbjct: 1131 C--------PGDHGMPGLRG------QPGEMGDPGPRGL-----------------QGDP 1159 Query: 587 SQEGYGTRSQPPLAPGKPNHEDLN-LIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSAS 645 G PP G LN L + SG D P G V Sbjct: 1160 GIPG------PPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGP-------VGIP 1206 Query: 646 GSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQ 705 G +GD +P SP P PG P S P G+ I PG Q Sbjct: 1207 GLKGERGDPGSPGISPPGPRGK---KGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQ 1263 Query: 706 MPPQP------PGSQSESSSHPALSQSP-------------MPQERGFMAGTQRNPQMAQ 746 PP P PG S L P P G+ + + Q Sbjct: 1264 GPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQ 1323 Query: 747 YGPQQTGPSMSPHPSPGGQMHAGISSFQ-QSNSSGTYGPQMSQYGPQGNYSRPPAYSGVP 805 GP PH PG G+ + +G GP+ + GP + P G+P Sbjct: 1324 KGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPR-GEPGPPADVDDCPRIPGLP 1382 Query: 806 SA-SYSGPGPGMGISANNQMHGQGPSQP-CGAVP--LGRMPSAGMQNRPFPGNMSSMT-- 859 A GP MG+ +GPS P C P GR G+ P P T Sbjct: 1383 GAPGMRGPEGAMGLPGM-----RGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGE 1437 Query: 860 ------PSSPGMSQQGGP-GMGP 875 P PG GP G GP Sbjct: 1438 DGYPGGPGPPGPIGDPGPKGFGP 1460 Score = 79.3 bits (194), Expect = 4e-14 Identities = 203/809 (25%), Positives = 264/809 (32%), Gaps = 153/809 (18%) Query: 137 PAGGR-----YEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAG 191 P GGR + P G+ G PP P G GP P GP G +G Sbjct: 46 PCGGRDCSVCHCVPEKGSRGPPGPPG--PQGPIGPLGAP--------------GPIGLSG 89 Query: 192 PCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGG 251 G + PG AAG G P G+P + PG+ P G Sbjct: 90 EK-GMRGDRGPPG----------AAGDKGDKGP--TGVPGFPG--LDGIPGHPGPPGPRG 134 Query: 252 GGGGGGGGGGSGGGGGGGGAGAGGAGA-----------GAVAAAAAAAAAAAGGGGGGGY 300 G G G G G GG GA G G G A G G G Sbjct: 135 KPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGL 194 Query: 301 GG--SSAGYGVLSSPRQQGG--GMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSG 356 G S G G + P G G++ PG G L K G G G+ Sbjct: 195 PGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGL-KGNPGVGVKGQMGDPGEVGQQGS 253 Query: 357 ATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGM- 415 PT LL P P Y G P P P + +G A G++ G Sbjct: 254 PGPT---LLVEP-PDFCLYKGEKGIKGIPGMVGLP--GPPGRKGESGIGAKGEKGIPGFP 307 Query: 416 GLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGR----SQGSPMDPMVMKRPQLY 471 G D G+ SP + + PG G + ++G P P V+ P L Sbjct: 308 GPRGDPGSY---GSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPL- 363 Query: 472 GMGSNPHSQPQQSSPYPG-----GSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDA 526 P P +PG G GPPGP G+ GR A AGM P Sbjct: 364 -----PLKGPPGDPGFPGRYGETGDVGPPGPP----GLLGRPGEACAGMIGP-------- 406 Query: 527 TWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLP--PQAQYLPSQSQQRYQPQQ 584 + F +P G+ G+ G + P +P P LP P Q LP S Y Sbjct: 407 PGPQGFPGLPGLPGEAGIPG--RPDSAPGKPGKPGSPGLPGAPGLQGLPG-SSVIYCSVG 463 Query: 585 DMSQEGYGTRSQPPLA---PGKPNHEDLNLIQ-----QERPSSLPDLSGSIDDLPTGTEA 636 + +G + PP G+ +E L + P LP GS DL Sbjct: 464 NPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDL------ 517 Query: 637 TLSSAVSASGSTSSQGDQSNP-AQSPFSPHASPHLSSIPG--GPSPSPVGSPVGSNQSRS 693 G ++GD P A+ P S PG G V S V ++ Sbjct: 518 ------GLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGER 571 Query: 694 GPISPASIP------------GSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRN 741 GP P P G + P PPG +++ P P P AG Sbjct: 572 GPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDAT--PGGKGFPGPLGPPGKAGPVGP 629 Query: 742 PQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAY 801 P + GP P HP G H G+ G G +S PP + Sbjct: 630 PGLGFPGP----PGERGHPGVPG--HPGVRG--PDGLKGQKGDTISCNVTYPGRHGPPGF 681 Query: 802 SGVPS-ASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSM-- 858 G P + GP G+S ++ G+ + +P M + F G S Sbjct: 682 DGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPV 741 Query: 859 ----TPSSPGMS-QQGGPG------MGPP 876 P SPG++ Q+G PG +GPP Sbjct: 742 GPPGPPGSPGVNGQKGIPGDPAFGHLGPP 770 Score = 67.8 bits (164), Expect = 1e-10 Identities = 253/1039 (24%), Positives = 313/1039 (30%), Gaps = 203/1039 (19%) Query: 84 GAGGGAPQPG-PDMEQPQHGGAK----DSAAGGQADPPGPPLLSKPGD---------EDD 129 G G QPG P ++ G K D GQ PGP LL +P D Sbjct: 217 GLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKG 276 Query: 130 APPKMGEPA-GGRYEHPGLGALGTQQPPVAVPGGGGGPAAV--PEFNNYYGSAAPASGGP 186 P +G P GR G+GA G + P PG G P + P F G G P Sbjct: 277 IPGMVGLPGPPGRKGESGIGAKGEKGIP-GFPGPRGDPGSYGSPGFPGLKGELG-LVGDP 334 Query: 187 G--GRAGPCFDQHGGQQSPG-MGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCN----H 239 G G GP D G + PG G++ + G PG DP G+P Sbjct: 335 GLFGLIGPKGDP-GNRGHPGPPGVLVTPPLPLKGPPG--DP------GFPGRYGETGDVG 385 Query: 240 YPG----YSRPG-AGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGG 294 PG RPG A G G G G G G G AG G A + G Sbjct: 386 PPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPG 445 Query: 295 GGG-GGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAA------------ 341 G G GSS Y + +P QG +GP GG K G A Sbjct: 446 APGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPP 505 Query: 342 --GGFQRFAGQ-----------NQHPSGA--TPTLNQLLTSPSP---------MMRSYGG 377 G Q G + P GA P L + P M+ S Sbjct: 506 GLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVK 565 Query: 378 SYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQ 437 + P PP P QP S A G G G + P Sbjct: 566 GHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGK---GFPGPLGPPG 622 Query: 438 RSHPAMSPGT--PGPTMGRSQ-GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPG----- 489 ++ P PG PGP R G P P V L G + S + YPG Sbjct: 623 KAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTIS---CNVTYPGRHGPP 679 Query: 490 GSYGPPGPQRYPIGIQGR-----------TPGAMAGMQYP-------QQQDSGDATWKET 531 G GPPGP+ +P G QG PG + P D G K + Sbjct: 680 GFDGPPGPKGFP-GPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGS 738 Query: 532 FWLMPP-QYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQY----LPSQSQQRYQPQQDM 586 + PP G GV+G Q P HL P + +P R P Sbjct: 739 SPVGPPGPPGSPGVNG------QKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPG 792 Query: 587 SQ--------------EGYGTRSQPPLAPGKPNHEDLNLIQQERPS-----SLPDLSGSI 627 ++ +G + P PG P H ++ P LP GS Sbjct: 793 AEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHS----CERGAPGIPGQPGLPGYPGS- 847 Query: 628 DDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVG 687 P G V G +G P + H P L IPG + P G Sbjct: 848 PGAPGGKGQ--PGDVGPPGPAGMKGLPGLPGRP--GAHGPPGLPGIPGPFGDDGLPGPPG 903 Query: 688 SNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQY 747 R P P PG + P G S +P +RG + Sbjct: 904 PKGPRGLPGFP-GFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGA---KGAIGPP 959 Query: 748 GPQQTGPSMSPHPSPGGQMHAGISSFQ-QSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPS 806 G + +S +PG G F + GT G Q + G G Y P + G P Sbjct: 960 GDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQ-GRRGEPGRYGPPGFHRGEPG 1018 Query: 807 ASYSGPGPGMGISANNQMHGQGPSQPCGAVPL-------GRMPSAGMQNRPFPGNMSSMT 859 PGP GP P G+ L G G P P S + Sbjct: 1019 EK-GQPGP------------PGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGID 1065 Query: 860 PSSPGMSQQGGPG--MGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMAS 917 + +G P GPP P K + + G F + GL Sbjct: 1066 GARGPKGNKGDPASHFGPPGP----KGEPGSPGC-----------PGHFGASGEQGLPGI 1110 Query: 918 SSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEE 977 P P PP S P GL PGE P P G + Sbjct: 1111 QGPRGSP--------GRPGPPGSSGPPGCPGDHGMPGLRG--QPGEMGDPGPRGLQG-DP 1159 Query: 978 GTPQPESKSKKSSSSTTTG 996 G P P S S G Sbjct: 1160 GIPGPPGIKGPSGSPGLNG 1178 Score = 53.9 bits (128), Expect = 2e-06 Identities = 67/219 (30%), Positives = 74/219 (33%), Gaps = 25/219 (11%) Query: 84 GAGGGAPQPGPDMEQP-QHGGAKDSAAGGQADPPGPP-----LLSKPGDED-DAPPKMGE 136 GA G AP+ PD P G G PPG P L +PGD PP Sbjct: 1245 GATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPG 1304 Query: 137 PAG--GRYEHPGLGALGTQQPPVAVPGGGG-----GPAAVPEFNNYYGSAAPAS-GGPGG 188 P G G PG Q+ PV PG G GP G P GP G Sbjct: 1305 PPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRG 1364 Query: 189 RAGPCFDQHGGQQSPGM----GMMHSASAAAAGAPGSMDPLQNSHEGYPNSQ----CNHY 240 GP D + PG+ GM A G PG P +G P + Sbjct: 1365 EPGPPADVDDCPRIPGLPGAPGMR--GPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGV 1422 Query: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAG 279 PG P G G G GG G G G G G G G Sbjct: 1423 PGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGFGPG 1461 Score = 39.7 bits (91), Expect = 0.033 Identities = 114/495 (23%), Positives = 148/495 (29%), Gaps = 98/495 (19%) Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDED--------DAPPKMG 135 G G +PG H G + GQ PPGPP PG P G Sbjct: 996 GMQGRRGEPGRYGPPGFHRG--EPGEKGQPGPPGPP--GPPGSTGLRGFIGFPGLPGDQG 1051 Query: 136 EPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPC-F 194 EP G PG + + P G G PA+ ++G P G PG P F Sbjct: 1052 EP--GSPGPPGFSGIDGARGP---KGNKGDPAS------HFGPPGP-KGEPGSPGCPGHF 1099 Query: 195 DQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNH-YPGY-SRPGAGGGG 252 G Q PG+ G+PG P +S G P +H PG +PG G Sbjct: 1100 GASGEQGLPGI-------QGPRGSPGRPGPPGSS--GPPGCPGDHGMPGLRGQPGEMGDP 1150 Query: 253 GGGG--GGGGGSGGGGGGGGAGAGGAGA-----GAVAAAAAAAAAAAGGGGGGGYGGSSA 305 G G G G G G G +G+ G G A+ G G G G Sbjct: 1151 GPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKG 1210 Query: 306 GYGVLSSP--RQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQ 363 G SP G GP G +S AG+ + P + Sbjct: 1211 ERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDG 1270 Query: 364 LLTSPSP--------MMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGM 415 +P P ++R G P PP PP P + GQ+ G Sbjct: 1271 PRGAPGPPGLPGSVDLLRGEPGDCG-LPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGF 1329 Query: 416 ----------------------------GLGKDMGAQYAAAS-------PAWAAAQQRSH 440 GL G A P A Sbjct: 1330 PGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRG 1389 Query: 441 PAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSS---------PYPGGS 491 P + G PG G +P + R + G+ +P ++ P P G Sbjct: 1390 PEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGP 1449 Query: 492 YGPPGPQRYPIGIQG 506 G PGP+ + G G Sbjct: 1450 IGDPGPKGFGPGYLG 1464 >gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo sapiens] Length = 1494 Score = 89.0 bits (219), Expect = 5e-17 Identities = 241/920 (26%), Positives = 291/920 (31%), Gaps = 185/920 (20%) Query: 80 NSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAG 139 + + G G PGP E G D PPG P PG A P G P Sbjct: 568 DGIPGTPGVKGLPGPKGELALSGEKGDQG------PPGDP--GSPGSPGPAGPA-GPPGY 618 Query: 140 GRYEHPGLGALGTQQPPVAVPGGGGGPA-AVPEFNNYYGSAAPASGGPGGRAGPCFDQHG 198 G PGL GTQ VPG G P A P + P GP G G H Sbjct: 619 GPQGEPGLQ--GTQ----GVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG-----HP 667 Query: 199 GQQSPGMGMMHSASAAAAGAPGSM----DPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGG 254 G Q P G PGS+ DP +G P +PG P G G Sbjct: 668 GPQGP------------PGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPG 715 Query: 255 GGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPR 314 G G G G G G G GA A A G G G G+S +G + P Sbjct: 716 TKGSLGCPGKMGEPGLPGKPGL-PGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPG 774 Query: 315 QQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQN-QHPSGAT--PTLNQLLTS---- 367 G + PG G G Q G+ + P GA P LN L Sbjct: 775 LPG--LPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRR 832 Query: 368 --------PSPMMRSYGGSYPEYSSPSAPPPPPSQ-PQSQAAAAG----AAAGGQQAAAG 414 P G E SP P P Q G G+ G Sbjct: 833 GKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIG 892 Query: 415 MGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPG-------PTMGRSQGSPMDPMVMK- 466 M MG A P SPG PG P QG +P + Sbjct: 893 M-----MGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEI 947 Query: 467 --------RPQLYGMGSNPHSQPQQSSP-YPG--------GSYGPPGPQRYPIGIQGRT- 508 P L G NP + + P PG G GPPGP R +G G Sbjct: 948 SHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGP-RGDLGSTGNPG 1006 Query: 509 -------PGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSG-YCQQGQ--QPYYSQ 558 PG+M M P + K P + G+ G+ G + QG +P YS+ Sbjct: 1007 EPGLRGIPGSMGNMGMPGSKG------KRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSE 1060 Query: 559 QPQP-PHLPPQAQYLPSQSQQRYQPQQD--------MSQEGYGTRSQPPLAPGKPN-HED 608 +P P P LP ++ + Q EG P PGKP H D Sbjct: 1061 GTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGD 1120 Query: 609 LNLIQQER---------PSSLPDLSGSIDDLPTGTEAT-----LSSAVSASGST----SS 650 L + P LP GS P G + G T + Sbjct: 1121 LGFKGIKGLLGPPGIRGPPGLPGFPGSPG--PMGIRGDQGRDGIPGPAGEKGETGLLRAP 1178 Query: 651 QGDQSNP-AQSPFSPHASPHLSSIPG-----------GPS-----PSPVGSP---VGSNQ 690 G + NP AQ +P +PG GP+ P P G P + Sbjct: 1179 PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT 1238 Query: 691 SRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQS-PMPQERGFMAGTQRNPQMAQYGP 749 GP PG+ PP PPGS S P P+ AG P + G Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPP--GRLGA 1296 Query: 750 QQTGPSMSPHPSPGGQMHAGISSFQQSNSS--GTYGPQMSQYGPQGNYSRPPAYSGVPSA 807 T P PG Q G+ ++ N G+ GP GP+G PP G P Sbjct: 1297 PGTPGLPGPRGDPGFQGFPGVKG-EKGNPGFLGSIGPP-GPIGPKG----PPGVRGDPGT 1350 Query: 808 ----SYSG-PGPGMGISANNQMHGQ-GPSQPCGAV----PLGRMPSAGMQNRPFP----G 853 S G PGP G M G+ GP P G + P G+ G P P G Sbjct: 1351 LKIISLPGSPGP-PGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409 Query: 854 NMSSMTPSSPGMSQQGGPGM 873 N S P S G PG+ Sbjct: 1410 NKGSKGEPGPAGS-DGLPGL 1428 Score = 75.1 bits (183), Expect = 7e-13 Identities = 162/681 (23%), Positives = 207/681 (30%), Gaps = 144/681 (21%) Query: 79 NNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPK--MGE 136 N L G G QPGP EQ G + G Q P L + G PK G Sbjct: 784 NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGI 843 Query: 137 PAGGRYEHPG-------------LGALGTQ----QPPVAVPGGGGGPAAVPEFNNYYGSA 179 P R PG +G LG + P + P G G + F G Sbjct: 844 PGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPP 903 Query: 180 APAS--GGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPN-SQ 236 P G PG R P GQ+ G PG+ + +G P S+ Sbjct: 904 GPPGNPGTPGQRGSPGIPGVKGQR---------------GTPGAKG--EQGDKGNPGPSE 946 Query: 237 CNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGG 296 +H G G G G G G G G G G A + G G Sbjct: 947 ISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPG 1006 Query: 297 GGGYGGSSAGYGVLSSPRQQGGGMMMG-PGGGGAASLSKAAAGSAAGGFQRFAGQNQHPS 355 G G G + P +G +G PG G L G Q G+ + Sbjct: 1007 EPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGL------PGIHGLQGDKGEPGYSE 1060 Query: 356 GATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAG- 414 G P PP P P GQ G Sbjct: 1061 GTRP---------------------------GPPGPTGDPGLPGDMGKKGEMGQPGPPGH 1093 Query: 415 MGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGP--TMGRS--QGSPMDPMVMKRPQL 470 +G GA + SP PG PGP +G +G P + P L Sbjct: 1094 LGPAGPEGAPGSPGSPG------------LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGL 1141 Query: 471 YGMGSNP------HSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSG 524 G +P Q + P P G G G R P G +G PGA + D G Sbjct: 1142 PGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRG-NPGAQGA-----KGDRG 1195 Query: 525 DATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQ 584 + P G++G G P PP LP +P Q+ R P Sbjct: 1196 APGF-------PGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP--GAIIPGQTGNRGPP-- 1244 Query: 585 DMSQEGYGTRSQP--PLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLS--S 640 G+R P P PG P + + + P G P GT + Sbjct: 1245 -------GSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKG-----PPGTAGDMGPPG 1292 Query: 641 AVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPS-------PSPVGSPVGSNQSRS 693 + A G+ G + +P F P + G P P P+G P G R Sbjct: 1293 RLGAPGTPGLPGPRGDPGFQGF-----PGVKGEKGNPGFLGSIGPPGPIG-PKGPPGVRG 1346 Query: 694 GP--ISPASIPGSQMPPQPPG 712 P + S+PGS PP PG Sbjct: 1347 DPGTLKIISLPGSPGPPGTPG 1367 Score = 72.8 bits (177), Expect = 4e-12 Identities = 217/911 (23%), Positives = 283/911 (31%), Gaps = 207/911 (22%) Query: 106 DSAAG--GQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGG 163 D A G G+ PGPP PG + P+ G PGL P + G Sbjct: 42 DGAKGEKGEKGFPGPP--GSPGQKGFTGPEGLPGPQGPKGFPGL-------PGLTGSKGV 92 Query: 164 GGPAAVPEFNNYYG-SAAPASGGPGGRAGP--CFDQHGGQQSPGM-------GMMHSASA 213 G + +P F+ G P + GP G G C G Q PG+ G+ +A Sbjct: 93 RGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGL 152 Query: 214 AAA-GAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAG 272 GAP + ++ +G P PG P G G G G G G G G Sbjct: 153 KGQKGAPAKEEDIELDAKGDPG-----LPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPG 207 Query: 273 AGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGV----LSSPRQQGG--------GM 320 A G G G G G G G L+ P + G Sbjct: 208 AMGP-RGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGA 266 Query: 321 MMGPGGGGAASLSKAAAGSAAG-----GFQRFAGQNQHPS-----------------GAT 358 M PG G + L + GS G G Q G++ P G Sbjct: 267 MGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGED 326 Query: 359 PTLNQLLTSPSPMMRS---YGGSYPEYSSPSAPPPP----------PSQPQSQAAAAGAA 405 Q P R Y +Y E P PP PS P + G++ Sbjct: 327 GIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSS 386 Query: 406 AGGQQAAAGM-GL----------GKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGR 454 G + A G GL GKD A SP A + PG PG + R Sbjct: 387 RPGLRGAPGWPGLKGSKGERGRPGKD--AMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFR 444 Query: 455 SQGSPMD---PMVMKRPQLYGMGSNPHSQPQ---QSSPYPGGSYGPPGPQRYPIGIQGRT 508 +G P D P + P + G+ P +P PY G G PG Sbjct: 445 -KGPPGDHGLPGYLGSPGIPGV-DGPKGEPGLLCTQCPYIPGPPGLPG-----------L 491 Query: 509 PGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQ 568 PG P G+QG +G P + P P P Sbjct: 492 PGLHGVKGIP---------------------GRQGAAGLKGSPGSPGNTGLPGFPGFPG- 529 Query: 569 AQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSID 628 AQ P ++ + Q Q G P L G+P + L+ I + L G Sbjct: 530 AQGDPGLKGEKGETLQPEGQ--VGVPGDPGLR-GQPGRKGLDGIPGT--PGVKGLPGPKG 584 Query: 629 DLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSS---IPGGPSP------ 679 +L E GS S G + P P L +PG P P Sbjct: 585 ELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGP 644 Query: 680 -------SPVGSPVG--SNQSRSGPISPASIPGS-----------------------QMP 707 +PV P G GP P IPGS P Sbjct: 645 RGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGP 704 Query: 708 PQP------PGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPS 761 P P PG++ + + +P + G + G + P +A G GP P Sbjct: 705 PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPG-LPGAKGEPAVAMPG----GPGTPGFPG 759 Query: 762 PGGQM--HAGISSFQQSNSSGTYGPQMSQYGPQGNYSR--PPAYSGVPSASYSGPGPGMG 817 G H I GT G + GP+G+ + PP G P GP G Sbjct: 760 ERGNSGEHGEIGLPGLPGLPGTPGNE-GLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQG 818 Query: 818 ISANNQMHGQ-------GPSQPCGAVPLGRMPSAGMQNRP-FPGNMSSMTPSSPGMSQQG 869 + N + GQ GP G L R G P PG+ M P + Q+G Sbjct: 819 LPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGP----LGQRG 874 Query: 870 GPG----MGPP 876 PG +GPP Sbjct: 875 YPGNPGILGPP 885 Score = 70.9 bits (172), Expect = 1e-11 Identities = 202/860 (23%), Positives = 267/860 (31%), Gaps = 174/860 (20%) Query: 88 GAPQPGPDMEQPQHGGAKDSAAGGQADPPGPP-------------LLSKPGDEDDAPPK- 133 GAP D+E G A G PGPP PG PK Sbjct: 157 GAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216 Query: 134 -MGEPAGGRYEHPGL-GALGTQQPPVAVPGGGGGPAAVPEFNNYYG-SAAPASGGPGGRA 190 MGE G G+ G G PP V GP + G A GP G + Sbjct: 217 HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS 276 Query: 191 GPCFDQHGGQQSPGMGMMHSASAAAAGAPGSM-DPLQNSHEGYPNSQ----CNHYPG-YS 244 G + +G ++ A G PG P ++ G+P S+ +PG Sbjct: 277 GLPGESYGSEK------------GAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMG 324 Query: 245 RPGAGGGGGGGGGGG--------------GGSGGGGGGGGAGAGG--AGAGAVAAAAAAA 288 G G G G G G G G G GA G +G + Sbjct: 325 EDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPG 384 Query: 289 AAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFA 348 ++ G G G+ G G P + G PG G+ L + G F Sbjct: 385 SSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVF- 443 Query: 349 GQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAP--PPPPSQPQSQAAAAGAAA 406 + P G L + P + G P P P PP P Sbjct: 444 --RKGPPGDHGLPGYLGSPGIPGVDGPKGE-PGLLCTQCPYIPGPPGLPGLPGLHGVKGI 500 Query: 407 GGQQAAAGM-GLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTM--GRSQGSPMDPM 463 G+Q AAG+ G G P + AQ P + G G T+ G P DP Sbjct: 501 PGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ--GDPGLK-GEKGETLQPEGQVGVPGDPG 557 Query: 464 VMKRPQLYGMGSNPHSQPQQSSPYP---------GGSYGPPGPQRYPIGIQGRTPGAMAG 514 + +P G+ P + + P P G GPPG P G G P AG Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSP-GSPG--PAGPAG 614 Query: 515 MQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPS 574 PP YG QG G QG Q P A P Sbjct: 615 ---------------------PPGYGPQGEPGL--QGTQGV-----------PGAPGPPG 640 Query: 575 QSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDD--LPT 632 ++ R + G PP PG P H + P +P G D LP Sbjct: 641 EAGPRGELSVSTPVPG------PPGPPGPPGHPG-----PQGPPGIPGSLGKCGDPGLPG 689 Query: 633 GTEATLSSAVSASGSTSSQGDQSNP-AQSPFSPHASPHLSSIPGGPS-PSPVGSPVGSNQ 690 + G +GDQ P + +PG P P G P Sbjct: 690 PDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPA---- 745 Query: 691 SRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQM--AQYG 748 ++PG P PG + S H + +P + GT N + + Sbjct: 746 --------VAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG----LPGTPGNEGLDGPRGD 793 Query: 749 PQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQ--MSQYGPQGNYSRPPAYSGVPS 806 P Q GP P PG + + +G G Q + GP+G+ P G+ Sbjct: 794 PGQPGPPGEQGP-PGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGD----PGIPGLDR 848 Query: 807 ASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPG-- 864 + + G GI + QG P G R +PGN + P PG Sbjct: 849 SGFPGETGSPGIPGH-----QGEMGPLG-------------QRGYPGNPGILGP--PGED 888 Query: 865 --MSQQGGPG-MGPPMPTVN 881 + G PG +GPP P N Sbjct: 889 GVIGMMGFPGAIGPPGPPGN 908 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.310 0.129 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 116,549,811 Number of Sequences: 37866 Number of extensions: 7807629 Number of successful extensions: 157798 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1373 Number of HSP's successfully gapped in prelim test: 2226 Number of HSP's that attempted gapping in prelim test: 51110 Number of HSP's gapped (non-prelim): 51652 length of query: 2191 length of database: 18,247,518 effective HSP length: 118 effective length of query: 2073 effective length of database: 13,779,330 effective search space: 28564551090 effective search space used: 28564551090 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.