Guide to the Human Genome
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Search of human proteins with 32469515

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|32469515 nudix-type motif 8 [Homo sapiens]
         (140 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32469515 nudix-type motif 8 [Homo sapiens]                         285   9e-78
gi|157785656 nudix motif 7 [Homo sapiens]                              62   2e-10
gi|51317351 RNA binding motif, single stranded interacting prote...    32   0.13 
gi|24308370 nudix-type motif 16 [Homo sapiens]                         30   0.49 
gi|110825988 TAR RNA binding protein 1 [Homo sapiens]                  30   0.84 
gi|39995071 exonuclease 1 isoform b [Homo sapiens]                     29   1.1  
gi|39995069 exonuclease 1 isoform a [Homo sapiens]                     29   1.1  
gi|18491016 exonuclease 1 isoform b [Homo sapiens]                     29   1.1  
gi|37594461 nudix-type motif 6 isoform b [Homo sapiens]                28   1.9  
gi|20149583 nudix-type motif 6 isoform a [Homo sapiens]                28   1.9  
gi|22219467 nudix-type motif 2 [Homo sapiens]                          28   2.5  
gi|22219465 nudix-type motif 2 [Homo sapiens]                          28   2.5  
gi|4502125 nudix-type motif 2 [Homo sapiens]                           28   2.5  
gi|38016930 2'-5'-oligoadenylate synthetase-like isoform b [Homo...    28   3.2  
gi|11321577 2'-5'-oligoadenylate synthetase-like isoform a [Homo...    28   3.2  
gi|223633890 hypothetical protein LOC729956 [Homo sapiens]             27   4.2  
gi|166795285 coenzyme Q4 homolog [Homo sapiens]                        27   4.2  
gi|239748777 PREDICTED: hypothetical protein [Homo sapiens]            27   4.2  
gi|92859618 sphingomyelin phosphodiesterase 2, neutral [Homo sap...    27   4.2  
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    27   5.5  
gi|41393549 nudix-type motif 10 [Homo sapiens]                         27   7.1  
gi|33667063 transmembrane protease, serine 9 [Homo sapiens]            27   7.1  
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]             26   9.3  
gi|169167201 PREDICTED: hypothetical protein [Homo sapiens]            26   9.3  

>gi|32469515 nudix-type motif 8 [Homo sapiens]
          Length = 140

 Score =  285 bits (729), Expect = 9e-78
 Identities = 140/140 (100%), Positives = 140/140 (100%)

Query: 1   MLPDCLSAEGELRCRRLLAGATARLRARPASAAVLVPLCSVRGVPALLYTLRSSRLTGRH 60
           MLPDCLSAEGELRCRRLLAGATARLRARPASAAVLVPLCSVRGVPALLYTLRSSRLTGRH
Sbjct: 1   MLPDCLSAEGELRCRRLLAGATARLRARPASAAVLVPLCSVRGVPALLYTLRSSRLTGRH 60

Query: 61  KGDVSFPGGKCDPADQDVVHTALRETREELGLAVPEEHVWGLLRPVYDPQKATVVPVLAG 120
           KGDVSFPGGKCDPADQDVVHTALRETREELGLAVPEEHVWGLLRPVYDPQKATVVPVLAG
Sbjct: 61  KGDVSFPGGKCDPADQDVVHTALRETREELGLAVPEEHVWGLLRPVYDPQKATVVPVLAG 120

Query: 121 VGPLDPQSLRPNSEEVSWGI 140
           VGPLDPQSLRPNSEEVSWGI
Sbjct: 121 VGPLDPQSLRPNSEEVSWGI 140


>gi|157785656 nudix motif 7 [Homo sapiens]
          Length = 238

 Score = 62.0 bits (149), Expect = 2e-10
 Identities = 43/105 (40%), Positives = 56/105 (53%), Gaps = 5/105 (4%)

Query: 33  AVLVPLCSVRGVPALLYTLRSSRLTGRHKGDVSFPGGKCDPADQDVVHTALRETREELGL 92
           +VL+PL +  G   LL+T+RS +L  R  G+V FPGGK DP D D   TALRE +EE+GL
Sbjct: 41  SVLLPLVAKEGKLHLLFTVRSEKLR-RAPGEVCFPGGKRDPTDMDDAATALREAQEEVGL 99

Query: 93  AVPEEHVWGLLRPVYDPQKATVVPVLAGVGPLDPQ-SLRPNSEEV 136
              +  V   L P        + P    VG +D     +PN  EV
Sbjct: 100 RPHQVEVVCCLVPCLIDTDTLITPF---VGLIDHNFQAQPNPAEV 141


>gi|51317351 RNA binding motif, single stranded interacting protein
           3 isoform 2 [Homo sapiens]
          Length = 420

 Score = 32.3 bits (72), Expect = 0.13
 Identities = 20/71 (28%), Positives = 30/71 (42%), Gaps = 3/71 (4%)

Query: 67  PGGKCDPADQDVVHTALRETREELGLAVPEEHVWGLLRPVYDPQKATVVPVLAGVGPLDP 126
           P     P  Q + H +L  T   +  A P +   G   P Y P   T V +   V    P
Sbjct: 329 PANMMGPLTQQMNHLSLGTTGTYMTAAAPMQ---GTYIPQYTPVPPTAVSIEGVVADTSP 385

Query: 127 QSLRPNSEEVS 137
           Q++ P+S++ S
Sbjct: 386 QTVAPSSQDTS 396


>gi|24308370 nudix-type motif 16 [Homo sapiens]
          Length = 162

 Score = 30.4 bits (67), Expect = 0.49
 Identities = 16/35 (45%), Positives = 19/35 (54%)

Query: 59 RHKGDVSFPGGKCDPADQDVVHTALRETREELGLA 93
          R  G + FPGG  D  D+ +     RE REELG A
Sbjct: 17 RFDGRLGFPGGFVDTQDRSLEDGLNRELREELGEA 51


>gi|110825988 TAR RNA binding protein 1 [Homo sapiens]
          Length = 1621

 Score = 29.6 bits (65), Expect = 0.84
 Identities = 40/113 (35%), Positives = 49/113 (43%), Gaps = 11/113 (9%)

Query: 27  ARPASAAVLVPLC-SVRGVPALLYTLRSSRLTGRHKGDVSFPGGKCDPADQDVVHTALRE 85
           AR  +A  LVPL  S+RG PA         L  RH+  V    G    A +  V  A   
Sbjct: 61  AREVAAGYLVPLLRSLRGRPA---GGPDPSLQPRHRRRVLRAAGA---ALRSCVRLA--- 111

Query: 86  TREELGLAVPEEHVWGLLRPVYDPQKATVVPVLAGVGP-LDPQSLRPNSEEVS 137
            R +L  A+ EE +  LL     P     V VLA VGP L P+   P  E V+
Sbjct: 112 GRPQLAAALAEEALRDLLAGWRAPGAEAAVEVLAAVGPCLRPREDGPLLERVA 164


>gi|39995071 exonuclease 1 isoform b [Homo sapiens]
          Length = 846

 Score = 29.3 bits (64), Expect = 1.1
 Identities = 14/49 (28%), Positives = 28/49 (57%), Gaps = 8/49 (16%)

Query: 89  ELGLAVPEEHVWGLLRP--------VYDPQKATVVPVLAGVGPLDPQSL 129
           ++ + VPE+++ G +R         V+DP K  ++P+ A    +DP++L
Sbjct: 262 KMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNAYEDDVDPETL 310


>gi|39995069 exonuclease 1 isoform a [Homo sapiens]
          Length = 803

 Score = 29.3 bits (64), Expect = 1.1
 Identities = 14/49 (28%), Positives = 28/49 (57%), Gaps = 8/49 (16%)

Query: 89  ELGLAVPEEHVWGLLRP--------VYDPQKATVVPVLAGVGPLDPQSL 129
           ++ + VPE+++ G +R         V+DP K  ++P+ A    +DP++L
Sbjct: 262 KMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNAYEDDVDPETL 310


>gi|18491016 exonuclease 1 isoform b [Homo sapiens]
          Length = 846

 Score = 29.3 bits (64), Expect = 1.1
 Identities = 14/49 (28%), Positives = 28/49 (57%), Gaps = 8/49 (16%)

Query: 89  ELGLAVPEEHVWGLLRP--------VYDPQKATVVPVLAGVGPLDPQSL 129
           ++ + VPE+++ G +R         V+DP K  ++P+ A    +DP++L
Sbjct: 262 KMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNAYEDDVDPETL 310


>gi|37594461 nudix-type motif 6 isoform b [Homo sapiens]
          Length = 147

 Score = 28.5 bits (62), Expect = 1.9
 Identities = 13/27 (48%), Positives = 19/27 (70%), Gaps = 1/27 (3%)

Query: 66 FPGGKCDPADQDVVHTALRETREELGL 92
          FPGG  +P ++D+  TA+RE  EE G+
Sbjct: 4  FPGGLSEP-EEDIGDTAVREVFEETGI 29


>gi|20149583 nudix-type motif 6 isoform a [Homo sapiens]
          Length = 316

 Score = 28.5 bits (62), Expect = 1.9
 Identities = 13/27 (48%), Positives = 19/27 (70%), Gaps = 1/27 (3%)

Query: 66  FPGGKCDPADQDVVHTALRETREELGL 92
           FPGG  +P ++D+  TA+RE  EE G+
Sbjct: 173 FPGGLSEP-EEDIGDTAVREVFEETGI 198


>gi|22219467 nudix-type motif 2 [Homo sapiens]
          Length = 147

 Score = 28.1 bits (61), Expect = 2.5
 Identities = 13/26 (50%), Positives = 18/26 (69%), Gaps = 1/26 (3%)

Query: 67 PGGKCDPADQDVVHTALRETREELGL 92
          P G  +P + D+  TALRET+EE G+
Sbjct: 41 PKGHVEPGEDDL-ETALRETQEEAGI 65


>gi|22219465 nudix-type motif 2 [Homo sapiens]
          Length = 147

 Score = 28.1 bits (61), Expect = 2.5
 Identities = 13/26 (50%), Positives = 18/26 (69%), Gaps = 1/26 (3%)

Query: 67 PGGKCDPADQDVVHTALRETREELGL 92
          P G  +P + D+  TALRET+EE G+
Sbjct: 41 PKGHVEPGEDDL-ETALRETQEEAGI 65


>gi|4502125 nudix-type motif 2 [Homo sapiens]
          Length = 147

 Score = 28.1 bits (61), Expect = 2.5
 Identities = 13/26 (50%), Positives = 18/26 (69%), Gaps = 1/26 (3%)

Query: 67 PGGKCDPADQDVVHTALRETREELGL 92
          P G  +P + D+  TALRET+EE G+
Sbjct: 41 PKGHVEPGEDDL-ETALRETQEEAGI 65


>gi|38016930 2'-5'-oligoadenylate synthetase-like isoform b [Homo
           sapiens]
          Length = 255

 Score = 27.7 bits (60), Expect = 3.2
 Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 3/93 (3%)

Query: 46  ALLYTLRSSRLTGRHKGDVSFPGGKCDPADQDVVHTALRETREELGLAVPEEHVWGL-LR 104
           A L    S +   +H  DV     K     QD++   L + R E    VP+  V+ +  R
Sbjct: 86  AFLSCFHSFQEAAKHHKDVLRLIWKTMWQSQDLLDLGLEDLRMEQ--RVPDALVFTIQTR 143

Query: 105 PVYDPQKATVVPVLAGVGPLDPQSLRPNSEEVS 137
              +P   T+VP    +GP  P S  P    VS
Sbjct: 144 GTAEPITVTIVPAYRALGPSLPNSQPPPEVYVS 176


>gi|11321577 2'-5'-oligoadenylate synthetase-like isoform a [Homo
           sapiens]
          Length = 514

 Score = 27.7 bits (60), Expect = 3.2
 Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 3/93 (3%)

Query: 46  ALLYTLRSSRLTGRHKGDVSFPGGKCDPADQDVVHTALRETREELGLAVPEEHVWGL-LR 104
           A L    S +   +H  DV     K     QD++   L + R E    VP+  V+ +  R
Sbjct: 86  AFLSCFHSFQEAAKHHKDVLRLIWKTMWQSQDLLDLGLEDLRMEQ--RVPDALVFTIQTR 143

Query: 105 PVYDPQKATVVPVLAGVGPLDPQSLRPNSEEVS 137
              +P   T+VP    +GP  P S  P    VS
Sbjct: 144 GTAEPITVTIVPAYRALGPSLPNSQPPPEVYVS 176


>gi|223633890 hypothetical protein LOC729956 [Homo sapiens]
          Length = 538

 Score = 27.3 bits (59), Expect = 4.2
 Identities = 23/57 (40%), Positives = 28/57 (49%), Gaps = 9/57 (15%)

Query: 17 LLAGATARLRARPASAAVLVPLCSVRGVPALLYTLRSSRLTGRHKGDVSFPGGKCDP 73
          LLA +  + RARP++A    P      +PALL  LR  RLTG   G     GG   P
Sbjct: 9  LLASSAGQARARPSNATSAEP---AGPLPALLAHLR--RLTGALTGG----GGAASP 56


>gi|166795285 coenzyme Q4 homolog [Homo sapiens]
          Length = 265

 Score = 27.3 bits (59), Expect = 4.2
 Identities = 12/21 (57%), Positives = 14/21 (66%)

Query: 82  ALRETREELGLAVPEEHVWGL 102
           +LR  REELG+  P  HV GL
Sbjct: 244 SLRALREELGITAPPMHVQGL 264


>gi|239748777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 350

 Score = 27.3 bits (59), Expect = 4.2
 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 5/56 (8%)

Query: 19  AGATARLRARPASAAVLVPLCSVRGVPALLYTLRSSRL----TGRHKGDVSFPGGK 70
           A   +RLRA PA+A  L+P   + G PA    L  SRL       H  + + P G+
Sbjct: 64  AAVHSRLRAAPAAAPRLLPRV-LAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGR 118


>gi|92859618 sphingomyelin phosphodiesterase 2, neutral [Homo
           sapiens]
          Length = 423

 Score = 27.3 bits (59), Expect = 4.2
 Identities = 16/59 (27%), Positives = 24/59 (40%)

Query: 42  RGVPALLYTLRSSRLTGRHKGDVSFPGGKCDPADQDVVHTALRETREELGLAVPEEHVW 100
           RG P   +    + L  RH      P     PA++  +   L+E   ELGL + +   W
Sbjct: 265 RGTPLSDHEALMATLFVRHSPPQQNPSSTHGPAERSPLMCVLKEAWTELGLGMAQARWW 323


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
           sapiens]
          Length = 1560

 Score = 26.9 bits (58), Expect = 5.5
 Identities = 15/37 (40%), Positives = 18/37 (48%)

Query: 92  LAVPEEHVWGLLRPVYDPQKATVVPVLAGVGPLDPQS 128
           L+VP   +     P  DP  AT V   AG+GP  P S
Sbjct: 716 LSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDS 752


>gi|41393549 nudix-type motif 10 [Homo sapiens]
          Length = 164

 Score = 26.6 bits (57), Expect = 7.1
 Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 1/52 (1%)

Query: 67  PGGKCDPADQDVVHTALRETREELGLAVPEEHVWGLLRPVYDPQKATVVPVL 118
           PGG  +P +++    A+RE  EE G+      + G+     DP+  T V VL
Sbjct: 48  PGGGMEP-EEEPGGAAVREVYEEAGVKGKLGRLLGVFEQNQDPKHRTYVYVL 98


>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
          Length = 1059

 Score = 26.6 bits (57), Expect = 7.1
 Identities = 12/25 (48%), Positives = 17/25 (68%), Gaps = 3/25 (12%)

Query: 50  TLRSSRLTGRHKGDVS---FPGGKC 71
           T+ S+ LTGRHKG ++   F  G+C
Sbjct: 130 TIVSAELTGRHKGPLAERDFKSGRC 154


>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
          Length = 4391

 Score = 26.2 bits (56), Expect = 9.3
 Identities = 9/20 (45%), Positives = 15/20 (75%)

Query: 60  HKGDVSFPGGKCDPADQDVV 79
           ++G+   PGGKC P +Q++V
Sbjct: 858 YEGNPIQPGGKCRPVNQEIV 877


>gi|169167201 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 145

 Score = 26.2 bits (56), Expect = 9.3
 Identities = 13/22 (59%), Positives = 16/22 (72%)

Query: 16 RLLAGATARLRARPASAAVLVP 37
          RL   ATAR RA+PAS+A  +P
Sbjct: 49 RLTDYATARARAQPASSAAQLP 70


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,022,037
Number of Sequences: 37866
Number of extensions: 269062
Number of successful extensions: 538
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 529
Number of HSP's gapped (non-prelim): 24
length of query: 140
length of database: 18,247,518
effective HSP length: 92
effective length of query: 48
effective length of database: 14,763,846
effective search space: 708664608
effective search space used: 708664608
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 56 (26.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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