BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|31543543 retinoic acid induced 17 [Homo sapiens] (1067 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|31543543 retinoic acid induced 17 [Homo sapiens] 2256 0.0 gi|54607108 zinc finger, MIZ-type containing 2 isoform 1 [Homo s... 1087 0.0 gi|54607110 zinc finger, MIZ-type containing 2 isoform 2 [Homo s... 1054 0.0 gi|115298686 protein inhibitor of activated STAT, 3 [Homo sapiens] 95 4e-19 gi|27532984 protein inhibitor of activated STAT X isoform alpha ... 90 1e-17 gi|56699458 protein inhibitor of activated STAT X isoform beta [... 90 1e-17 gi|24850133 protein inhibitor of activated STAT, 4 [Homo sapiens] 88 4e-17 gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 85 4e-16 gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 85 4e-16 gi|7706637 protein inhibitor of activated STAT, 1 [Homo sapiens] 83 2e-15 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 77 7e-14 gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 73 2e-12 gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 70 8e-12 gi|163965366 nascent polypeptide-associated complex alpha subuni... 70 1e-11 gi|150170670 piccolo isoform 2 [Homo sapiens] 69 2e-11 gi|150378539 piccolo isoform 1 [Homo sapiens] 69 2e-11 gi|47132519 Ras association and pleckstrin homology domains 1 is... 69 2e-11 gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 67 9e-11 gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 67 9e-11 gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 67 9e-11 gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 67 9e-11 gi|110832843 TBP-associated factor 4 [Homo sapiens] 66 2e-10 gi|55750053 atrophin-1 [Homo sapiens] 66 2e-10 gi|55750041 atrophin-1 [Homo sapiens] 66 2e-10 gi|42544123 splicing factor 1 isoform 3 [Homo sapiens] 66 2e-10 gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] 64 6e-10 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 64 8e-10 gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 64 8e-10 gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 63 1e-09 gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 63 2e-09 >gi|31543543 retinoic acid induced 17 [Homo sapiens] Length = 1067 Score = 2256 bits (5845), Expect = 0.0 Identities = 1067/1067 (100%), Positives = 1067/1067 (100%) Query: 1 MNSMDRHIQQTNDRLQCIKQHLQNPANFHNAATELLDWCGDPRAFQRPFEQSLMGCLTVV 60 MNSMDRHIQQTNDRLQCIKQHLQNPANFHNAATELLDWCGDPRAFQRPFEQSLMGCLTVV Sbjct: 1 MNSMDRHIQQTNDRLQCIKQHLQNPANFHNAATELLDWCGDPRAFQRPFEQSLMGCLTVV 60 Query: 61 SRVAAQQGFDLDLGYRLLAVCAANRDKFTPKSAALLSSWCEELGRLLLLRHQKSRQSDPP 120 SRVAAQQGFDLDLGYRLLAVCAANRDKFTPKSAALLSSWCEELGRLLLLRHQKSRQSDPP Sbjct: 61 SRVAAQQGFDLDLGYRLLAVCAANRDKFTPKSAALLSSWCEELGRLLLLRHQKSRQSDPP 120 Query: 121 GKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWGVTNTSQSQ 180 GKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWGVTNTSQSQ Sbjct: 121 GKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWGVTNTSQSQ 180 Query: 181 VLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQSMYG 240 VLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQSMYG Sbjct: 181 VLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQSMYG 240 Query: 241 RPNYPGSGGFGASYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATATATAT 300 RPNYPGSGGFGASYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATATATAT Sbjct: 241 RPNYPGSGGFGASYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATATATAT 300 Query: 301 ATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMGGSMNPASMAAGMTPSGM 360 ATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMGGSMNPASMAAGMTPSGM Sbjct: 301 ATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMGGSMNPASMAAGMTPSGM 360 Query: 361 SGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGP 420 SGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGP Sbjct: 361 SGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGP 420 Query: 421 NSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQPSSGQYPPPTVNMGQYYKPEQFNGQNN 480 NSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQPSSGQYPPPTVNMGQYYKPEQFNGQNN Sbjct: 421 NSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQPSSGQYPPPTVNMGQYYKPEQFNGQNN 480 Query: 481 TFSGSSYSNYSQGNVNRPPRPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPPF 540 TFSGSSYSNYSQGNVNRPPRPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPPF Sbjct: 481 TFSGSSYSNYSQGNVNRPPRPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPPF 540 Query: 541 PPDIKPNMSALPPPPANHNDELRLTFPVRDGVVLEPFRLEHNLAVSNHVFHLRPTVHQTL 600 PPDIKPNMSALPPPPANHNDELRLTFPVRDGVVLEPFRLEHNLAVSNHVFHLRPTVHQTL Sbjct: 541 PPDIKPNMSALPPPPANHNDELRLTFPVRDGVVLEPFRLEHNLAVSNHVFHLRPTVHQTL 600 Query: 601 MWRSDLELQFKCYHHEDRQMNTNWPASVQVSVNATPLTIERGDNKTSHKPLHLKHVCQPG 660 MWRSDLELQFKCYHHEDRQMNTNWPASVQVSVNATPLTIERGDNKTSHKPLHLKHVCQPG Sbjct: 601 MWRSDLELQFKCYHHEDRQMNTNWPASVQVSVNATPLTIERGDNKTSHKPLHLKHVCQPG 660 Query: 661 RNTIQITVTACCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCITKIKRNFSSVAASS 720 RNTIQITVTACCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCITKIKRNFSSVAASS Sbjct: 661 RNTIQITVTACCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCITKIKRNFSSVAASS 720 Query: 721 GNTTLNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCKHVQCFDLESYLQLNCERGTWR 780 GNTTLNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCKHVQCFDLESYLQLNCERGTWR Sbjct: 721 GNTTLNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCKHVQCFDLESYLQLNCERGTWR 780 Query: 781 CPVCNKTALLEGLEVDQYMWGILNAIQHSEFEEVTIDPTCSWRPVPIKSDLHIKDDPDGI 840 CPVCNKTALLEGLEVDQYMWGILNAIQHSEFEEVTIDPTCSWRPVPIKSDLHIKDDPDGI Sbjct: 781 CPVCNKTALLEGLEVDQYMWGILNAIQHSEFEEVTIDPTCSWRPVPIKSDLHIKDDPDGI 840 Query: 841 PSKRFKTMSPSQMIMPNVMEMIAALGPGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFD 900 PSKRFKTMSPSQMIMPNVMEMIAALGPGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFD Sbjct: 841 PSKRFKTMSPSQMIMPNVMEMIAALGPGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFD 900 Query: 901 FPHGNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQ 960 FPHGNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQ Sbjct: 901 FPHGNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQ 960 Query: 961 QGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEGQAGA 1020 QGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEGQAGA Sbjct: 961 QGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEGQAGA 1020 Query: 1021 QGASDMPEPSLDLLPELTNPDELLSYLDPPDLPSNSNDDLLSLFENN 1067 QGASDMPEPSLDLLPELTNPDELLSYLDPPDLPSNSNDDLLSLFENN Sbjct: 1021 QGASDMPEPSLDLLPELTNPDELLSYLDPPDLPSNSNDDLLSLFENN 1067 >gi|54607108 zinc finger, MIZ-type containing 2 isoform 1 [Homo sapiens] Length = 920 Score = 1087 bits (2812), Expect = 0.0 Identities = 581/957 (60%), Positives = 687/957 (71%), Gaps = 55/957 (5%) Query: 129 LSSMSSMKPTLS---HSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWGVTNTSQSQVLGNP 185 ++SM+ MKP L H DGSF Y+SVPWQQ+ QP GSLSVVTTVWGV N +QSQVLGNP Sbjct: 1 MNSMNPMKPALPPAPHGDGSFAYESVPWQQSATQPAGSLSVVTTVWGVGNATQSQVLGNP 60 Query: 186 MANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQSMYGRPNYP 245 M A +P G+ M G+ + L SPQ GQQ A+ G + Y+QQ +Y R YP Sbjct: 61 MGPAGSP---SGSSMMPGVAGGSSALTSPQCLGQQA--FAEGGANKGYVQQGVYSRGGYP 115 Query: 246 GSGGFGASYPGGPNAPAGMGIPPHT-RPPADFTQPAAAAAAAAVAAAAATATATATATVA 304 G+ GF Y GGP G+G+P H RP DFTQ AAAAAAVAAAAATATATATATVA Sbjct: 116 GAPGFTTGYAGGPG---GLGLPSHAARPSTDFTQ---AAAAAAVAAAAATATATATATVA 169 Query: 305 ALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMGGSMNPASMAAGMTPSGMSGPP 364 ALQE Q+++++QYG MG Q++NSQF+ GPRGP+ G MNP + M PSG+S P Sbjct: 170 ALQEKQSQELSQYGAMGAGQSFNSQFLQHGGPRGPSVPAG-MNPTGIGGVMGPSGLS--P 226 Query: 365 MGMNQPRPPGISPFGTHGQRMPQQTYPGP-RPQSLPIQNIKRPY----PGEPNYGNQQYG 419 + MN R G++P GQR+PQ YPGP + Q LP Q +KR Y PG+ QY Sbjct: 227 LAMNPTRAAGMTPLYA-GQRLPQHGYPGPPQAQPLPRQGVKRTYSEVYPGQQYLQGGQYA 285 Query: 420 PNS-QFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQPSSGQ---YPPPTVNMGQYYKP-EQ 474 P++ QF PGQ PAP SP+YPG R+P Q Q P PT G +YKP EQ Sbjct: 286 PSTAQFAPSPGQPPAP-------SPSYPGHRLPLQQGMTQSLSVPGPT---GLHYKPTEQ 335 Query: 475 FNGQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQ 534 FNGQ +F+G S S YSQ ++ P R +P YP SP+PGNPTPPMTP SS+P Y+SP+Q Sbjct: 336 FNGQGASFNGGSVS-YSQPGLSGPTRSIP--GYPSSPLPGNPTPPMTPSSSVP-YMSPNQ 391 Query: 535 DVKPPFPPDIKPNMSALPPPPANHN--DELRLTFPVRDGVVLEPFRLEHNLAVSNHVFHL 592 +VK PF PD+KPN+++L P+ DELRLTFPVRDGVVLEPFRL+HNLAVSNHVF L Sbjct: 392 EVKSPFLPDLKPNLNSLHSSPSGSGPCDELRLTFPVRDGVVLEPFRLQHNLAVSNHVFQL 451 Query: 593 RPTVHQTLMWRSDLELQFKCYHHEDRQMNTNWPASVQVSVNATPLTIERGDNKTSHKPLH 652 R +V++TL+ R DLELQFKCYHHEDRQMNTNWPASVQVSVNATPLTIERGDNKTSHKPL+ Sbjct: 452 RDSVYKTLIMRPDLELQFKCYHHEDRQMNTNWPASVQVSVNATPLTIERGDNKTSHKPLY 511 Query: 653 LKHVCQPGRNTIQITVTACCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCITKIKRN 712 LKHVCQPGRNTIQITVTACCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCITKIKRN Sbjct: 512 LKHVCQPGRNTIQITVTACCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCITKIKRN 571 Query: 713 FSSVAASSGNTTLNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCKHVQCFDLESYLQL 772 FSS G NGEDGVEQTAIKVSLKCPITFRRIQLPARGHDC+H+QCFDLESYLQL Sbjct: 572 FSS-GTIPGTPGPNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCRHIQCFDLESYLQL 630 Query: 773 NCERGTWRCPVCNKTALLEGLEVDQYMWGILNAIQHSEFEEVTIDPTCSWRPVPIKSDLH 832 NCERGTWRCPVCNKTALLEGLEVDQYM GIL IQ+S++EE+TIDPTCSW+PVP+K D+H Sbjct: 631 NCERGTWRCPVCNKTALLEGLEVDQYMLGILIYIQNSDYEEITIDPTCSWKPVPVKPDMH 690 Query: 833 IKDDPDGIPSKRFKTMSPSQMIMPNVMEMIAALGPGPSPYPLPPPPGGTNSNDYSSQGNN 892 IK++PDG KR +T+SP+ ++MP+VMEMIAALGPG +P+ PP +DY QG++ Sbjct: 691 IKEEPDGPALKRCRTVSPAHVLMPSVMEMIAALGPGAAPFAPLQPPSVPAPSDYPGQGSS 750 Query: 893 YQGHGNF--DFPHGNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAG 950 + G G F FP P ++ +F GPP +S+ D+P+++ EK + + M AG Sbjct: 751 FLGPGTFPESFPPTTPSTPTLAEFTPGPPPISYQSDIPSSLLTSEKSTA-CLPSQMAPAG 809 Query: 951 SSDQPHPSIQQGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSHPHSDLTFNP 1010 D H GLH + + GP LHHS PPP Q Q S P +L F+P Sbjct: 810 HLDPTHNPGTPGLHTSNLGAPPGPQLHHSN-PPPASRQSLGQ-----ASLGPTGELAFSP 863 Query: 1011 SSALEGQAGAQGASDMPEPSLDLLPELTNPDELLSYLDPPDLPSNSNDDLLSLFENN 1067 ++ + G GA + PEP+LDLLPELTNPDELLSYL PPDLP+N+NDDLLSLFENN Sbjct: 864 ATGVMGPPSMSGAGEAPEPALDLLPELTNPDELLSYLGPPDLPTNNNDDLLSLFENN 920 >gi|54607110 zinc finger, MIZ-type containing 2 isoform 2 [Homo sapiens] Length = 894 Score = 1054 bits (2726), Expect = 0.0 Identities = 567/956 (59%), Positives = 669/956 (69%), Gaps = 79/956 (8%) Query: 129 LSSMSSMKPTLS---HSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWGVTNTSQSQVLGNP 185 ++SM+ MKP L H DGSF Y+SVPWQQ+ QP GSLSVVTTVWGV N +QSQVLGNP Sbjct: 1 MNSMNPMKPALPPAPHGDGSFAYESVPWQQSATQPAGSLSVVTTVWGVGNATQSQVLGNP 60 Query: 186 MANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQSMYGRPNYP 245 M A +P G+ M G+ + L SPQ GQQ A+ G + Y+QQ +Y R YP Sbjct: 61 MGPAGSP---SGSSMMPGVAGGSSALTSPQCLGQQA--FAEGGANKGYVQQGVYSRGGYP 115 Query: 246 GSGGFGASYPGGPNAPAGMGIPPHT-RPPADFTQPAAAAAAAAVAAAAATATATATATVA 304 G+ GF Y GGP G+G+P H RP DFTQ AAAAAAVAAAAATATATATATVA Sbjct: 116 GAPGFTTGYAGGPG---GLGLPSHAARPSTDFTQ---AAAAAAVAAAAATATATATATVA 169 Query: 305 ALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMGGSMNPASMAAGMTPSGMSGPP 364 ALQE Q+++++QYG MG Q++NSQF+ GPRGP+ G MNP + M PSG+S P Sbjct: 170 ALQEKQSQELSQYGAMGAGQSFNSQFLQHGGPRGPSVPAG-MNPTGIGGVMGPSGLS--P 226 Query: 365 MGMNQPRPPGISPFGTHGQRMPQQTYPGP-RPQSLPIQNIKRPY----PGEPNYGNQQYG 419 + MN R G++P GQR+PQ YPGP + Q LP Q +KR Y PG+ QY Sbjct: 227 LAMNPTRAAGMTPLYA-GQRLPQHGYPGPPQAQPLPRQGVKRTYSEVYPGQQYLQGGQYA 285 Query: 420 PNS-QFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQPSSGQ---YPPPTVNMGQYYKPEQF 475 P++ QF PGQ PAP SP+YPG R+P Q Q P PT G +YKP Sbjct: 286 PSTAQFAPSPGQPPAP-------SPSYPGHRLPLQQGMTQSLSVPGPT---GLHYKPT-- 333 Query: 476 NGQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQD 535 R +P YP SP+PGNPTPPMTP SS+P Y+SP+Q+ Sbjct: 334 ------------------------RSIP--GYPSSPLPGNPTPPMTPSSSVP-YMSPNQE 366 Query: 536 VKPPFPPDIKPNMSALPPPPANHN--DELRLTFPVRDGVVLEPFRLEHNLAVSNHVFHLR 593 VK PF PD+KPN+++L P+ DELRLTFPVRDGVVLEPFRL+HNLAVSNHVF LR Sbjct: 367 VKSPFLPDLKPNLNSLHSSPSGSGPCDELRLTFPVRDGVVLEPFRLQHNLAVSNHVFQLR 426 Query: 594 PTVHQTLMWRSDLELQFKCYHHEDRQMNTNWPASVQVSVNATPLTIERGDNKTSHKPLHL 653 +V++TL+ R DLELQFKCYHHEDRQMNTNWPASVQVSVNATPLTIERGDNKTSHKPL+L Sbjct: 427 DSVYKTLIMRPDLELQFKCYHHEDRQMNTNWPASVQVSVNATPLTIERGDNKTSHKPLYL 486 Query: 654 KHVCQPGRNTIQITVTACCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCITKIKRNF 713 KHVCQPGRNTIQITVTACCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCITKIKRNF Sbjct: 487 KHVCQPGRNTIQITVTACCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCITKIKRNF 546 Query: 714 SSVAASSGNTTLNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCKHVQCFDLESYLQLN 773 SS G NGEDGVEQTAIKVSLKCPITFRRIQLPARGHDC+H+QCFDLESYLQLN Sbjct: 547 SS-GTIPGTPGPNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCRHIQCFDLESYLQLN 605 Query: 774 CERGTWRCPVCNKTALLEGLEVDQYMWGILNAIQHSEFEEVTIDPTCSWRPVPIKSDLHI 833 CERGTWRCPVCNKTALLEGLEVDQYM GIL IQ+S++EE+TIDPTCSW+PVP+K D+HI Sbjct: 606 CERGTWRCPVCNKTALLEGLEVDQYMLGILIYIQNSDYEEITIDPTCSWKPVPVKPDMHI 665 Query: 834 KDDPDGIPSKRFKTMSPSQMIMPNVMEMIAALGPGPSPYPLPPPPGGTNSNDYSSQGNNY 893 K++PDG KR +T+SP+ ++MP+VMEMIAALGPG +P+ PP +DY QG+++ Sbjct: 666 KEEPDGPALKRCRTVSPAHVLMPSVMEMIAALGPGAAPFAPLQPPSVPAPSDYPGQGSSF 725 Query: 894 QGHGNF--DFPHGNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGS 951 G G F FP P ++ +F GPP +S+ D+P+++ EK + + M AG Sbjct: 726 LGPGTFPESFPPTTPSTPTLAEFTPGPPPISYQSDIPSSLLTSEKSTA-CLPSQMAPAGH 784 Query: 952 SDQPHPSIQQGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSHPHSDLTFNPS 1011 D H GLH + + GP LHHS PPP Q Q S P +L F+P+ Sbjct: 785 LDPTHNPGTPGLHTSNLGAPPGPQLHHSN-PPPASRQSLGQ-----ASLGPTGELAFSPA 838 Query: 1012 SALEGQAGAQGASDMPEPSLDLLPELTNPDELLSYLDPPDLPSNSNDDLLSLFENN 1067 + + G GA + PEP+LDLLPELTNPDELLSYL PPDLP+N+NDDLLSLFENN Sbjct: 839 TGVMGPPSMSGAGEAPEPALDLLPELTNPDELLSYLGPPDLPTNNNDDLLSLFENN 894 >gi|115298686 protein inhibitor of activated STAT, 3 [Homo sapiens] Length = 628 Score = 94.7 bits (234), Expect = 4e-19 Identities = 126/543 (23%), Positives = 198/543 (36%), Gaps = 83/543 (15%) Query: 498 PPRPVPVANYPHSPVPGNPTPP--MTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPPPP 555 PP PV SP P P PP + PG+ + P D+ PP P + P+++ P P Sbjct: 81 PPGTSPVG----SPGPLAPIPPTLLAPGTLLGP--KREVDMHPPLPQPVHPDVTMKPLP- 133 Query: 556 ANHNDELRLTFPVRDGVVLEPFRL----EHNLAVSNHVFHLRPTVHQTLMWRSDLELQFK 611 F G ++ P L ++ F L P Q ++ ++ K Sbjct: 134 ----------FYEVYGELIRPTTLASTSSQRFEEAHFTFALTPQQVQQILTSREVLPGAK 183 Query: 612 CYHHEDRQMN-----------TNWPASVQVSVNAT--------PLTIERGDNKTSHKPLH 652 C + Q+ +P ++ V VN P T + K +P++ Sbjct: 184 CDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPIN 243 Query: 653 LKHVCQPGRNTIQITVTACCCSHL-----FVLQLVHRPSVRSVLQGLLKKRLLPAEHCIT 707 + + + T+ T+ S + LV + + ++LQ L K + +H Sbjct: 244 ITPLARLSA-TVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRA 302 Query: 708 KIKRNFSSVAASSGNTTLNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCKHVQCFDLE 767 IK T + + V T+++VSL CP+ R+ +P R C H+Q FD Sbjct: 303 LIKEKL----------TADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAA 352 Query: 768 SYLQLNCERGTWRCPVCNKTALLEGLEVDQYMWGILNAIQHSEFEEVTIDPTCSWRPVPI 827 YLQ+N ++ TW CPVC+K A E L +D IL++ S+ +E+ SW P+ Sbjct: 353 LYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILSSC--SDCDEIQFMEDGSWCPMKP 410 Query: 828 KSDLHIKDDP-----DGIPSKRFKTMSPSQMIMPNVMEMIAALGPGPSPYPLPPPPGGTN 882 K + P DG+ + PS+ V + + LPP + Sbjct: 411 KKEASEVCPPPGYGLDGLQYSPVQGGDPSEN-KKKVEVIDLTIESSSDEEDLPPTKKHCS 469 Query: 883 SNDYS------SQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEK 936 + S+G GH GT DF+ P +PP P Sbjct: 470 VTSAAIPALPGSKGVLTSGHQPSSVLRSPAMGTLGGDFLSSLPLHEYPPAFPLGADIQGL 529 Query: 937 PLSHPMQETMPHAGSSDQPHPSIQQGL-----------HVPHPSSQSGPPLHHSGAPPPP 985 L +Q H G S Q L H P + + H S P PP Sbjct: 530 DLFSFLQTESQHYGPSVITSLDEQDALGHFFQYRGTPSHFLGPLAPTLGSSHCSATPAPP 589 Query: 986 PSQ 988 P + Sbjct: 590 PGR 592 >gi|27532984 protein inhibitor of activated STAT X isoform alpha [Homo sapiens] Length = 572 Score = 90.1 bits (222), Expect = 1e-17 Identities = 103/415 (24%), Positives = 168/415 (40%), Gaps = 54/415 (13%) Query: 456 SGQYPPPTVNMGQYYK---PEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHSPV 512 SG P + + + Y+ P G ++ + S S +S + P P HS + Sbjct: 47 SGCSPAVQIKIRELYRRRYPRTLEGLSDLSTIKS-SVFSLDGGSSPVEPDLAVAGIHS-L 104 Query: 513 PGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPPPPANHNDELRLTFPVRD-- 570 P P +P S + L QD KP F +P+ PP P H D P D Sbjct: 105 PSTSVTPHSPSSPVGSVLL--QDTKPTFEMQ-QPS----PPIPPVHPDVQLKNLPFYDVL 157 Query: 571 GVVLEPFRLEHN----LAVSNHVFHLRPTVHQTLMWRSD----------LELQFK-CYHH 615 V+++P L + +F L P + + D +++Q + C Sbjct: 158 DVLIKPTSLVQSSIQRFQEKFFIFALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAE 217 Query: 616 EDRQMNTNWPASVQVSVNA--------TPLTIERGDNKTSHKPLHLKHVCQPGR---NTI 664 N+P S+ + VN P + K +PL++ + + N I Sbjct: 218 TSCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQI 277 Query: 665 QIT-VTACCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCITKIKRNFSSVAASSGNT 723 I+ + ++ + LV + + +LQ L K + +H IK Sbjct: 278 SISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKL---------- 327 Query: 724 TLNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCKHVQCFDLESYLQLNCERGTWRCPV 783 T + + + T+++VSL CP+ R+ +P R C H+QCFD YLQ+N ++ TW CPV Sbjct: 328 TADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPV 387 Query: 784 CNKTALLEGLEVDQYMWGILNAIQHSEFEEVTIDPTCSWRPV-PIKSDLHIKDDP 837 C+K A E L +D ILN S+ +E+ SW P+ P K + + P Sbjct: 388 CDKKAAYESLILDGLFMEILN--DCSDVDEIKFQEDGSWCPMRPKKEAMKVSSQP 440 >gi|56699458 protein inhibitor of activated STAT X isoform beta [Homo sapiens] Length = 621 Score = 90.1 bits (222), Expect = 1e-17 Identities = 103/415 (24%), Positives = 168/415 (40%), Gaps = 54/415 (13%) Query: 456 SGQYPPPTVNMGQYYK---PEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHSPV 512 SG P + + + Y+ P G ++ + S S +S + P P HS + Sbjct: 47 SGCSPAVQIKIRELYRRRYPRTLEGLSDLSTIKS-SVFSLDGGSSPVEPDLAVAGIHS-L 104 Query: 513 PGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPPPPANHNDELRLTFPVRD-- 570 P P +P S + L QD KP F +P+ PP P H D P D Sbjct: 105 PSTSVTPHSPSSPVGSVLL--QDTKPTFEMQ-QPS----PPIPPVHPDVQLKNLPFYDVL 157 Query: 571 GVVLEPFRLEHN----LAVSNHVFHLRPTVHQTLMWRSD----------LELQFK-CYHH 615 V+++P L + +F L P + + D +++Q + C Sbjct: 158 DVLIKPTSLVQSSIQRFQEKFFIFALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAE 217 Query: 616 EDRQMNTNWPASVQVSVNA--------TPLTIERGDNKTSHKPLHLKHVCQPGR---NTI 664 N+P S+ + VN P + K +PL++ + + N I Sbjct: 218 TSCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQI 277 Query: 665 QIT-VTACCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCITKIKRNFSSVAASSGNT 723 I+ + ++ + LV + + +LQ L K + +H IK Sbjct: 278 SISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKL---------- 327 Query: 724 TLNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCKHVQCFDLESYLQLNCERGTWRCPV 783 T + + + T+++VSL CP+ R+ +P R C H+QCFD YLQ+N ++ TW CPV Sbjct: 328 TADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPV 387 Query: 784 CNKTALLEGLEVDQYMWGILNAIQHSEFEEVTIDPTCSWRPV-PIKSDLHIKDDP 837 C+K A E L +D ILN S+ +E+ SW P+ P K + + P Sbjct: 388 CDKKAAYESLILDGLFMEILN--DCSDVDEIKFQEDGSWCPMRPKKEAMKVSSQP 440 >gi|24850133 protein inhibitor of activated STAT, 4 [Homo sapiens] Length = 510 Score = 88.2 bits (217), Expect = 4e-17 Identities = 63/224 (28%), Positives = 101/224 (45%), Gaps = 22/224 (9%) Query: 612 CYHHEDRQMNTNWPASVQVSVNAT--------PLTIERGDNKTSHKPLHLKHVCQPGRNT 663 CY +P ++ V VN + P + K +P++L H+ T Sbjct: 196 CYSDTSCPQEDQYPPNIAVKVNHSYCSVPGYYPSNKPGVEPKRPCRPINLTHLMYLSSAT 255 Query: 664 IQITVT--ACCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCITKIKRNFSSVAASSG 721 +ITVT S+ L LV + + +LQ L + E C +K Sbjct: 256 NRITVTWGNYGKSYSVALYLVRQLTSSELLQRLKTIGVKHPELCKALVKEKLR------- 308 Query: 722 NTTLNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCKHVQCFDLESYLQLNCERGTWRC 781 L+ + + T ++VSL CP+ R+ +P R C H+QCFD YLQ+N ++ TW C Sbjct: 309 ---LDPDSEIATTGVRVSLICPLVKMRLSVPCRAETCAHLQCFDAVFYLQMNEKKPTWMC 365 Query: 782 PVCNKTALLEGLEVDQYMWGILNAIQHSEFEEVTIDPTCSWRPV 825 PVC+K A + L +D + IL+ + ++ E +D SW P+ Sbjct: 366 PVCDKPAPYDQLIIDGLLSKILSECEDADEIEYLVDG--SWCPI 407 >gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] Length = 2285 Score = 84.7 bits (208), Expect = 4e-16 Identities = 109/446 (24%), Positives = 144/446 (32%), Gaps = 77/446 (17%) Query: 120 PGKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWGVTNTSQS 179 P + PP + + LS G P + PP S + ++ +++S + Sbjct: 217 PNRSAYPPPAPAYA-----LSSPRGGTPGSGAAAAAGSKPPPSSSASASS----SSSSFA 267 Query: 180 QVLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQSMY 239 Q M GG P + T N L SP S Sbjct: 268 QQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPS---------------------SAR 306 Query: 240 GRPNYPGSGGFGASYPGGP-NAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATATAT 298 G YPG Y GGP + AG G PAD AAAAA AAAAA+ A Sbjct: 307 GYQGYPGG-----DYSGGPQDGGAGKG-------PADMASQCWGAAAAAAAAAAASGGA- 353 Query: 299 ATATVAALQETQNKDINQYGPMGPTQAYNS--QFMNQPGPRGPASMGGSMNPASMAAGMT 356 + + + PM P + P P P G M P Sbjct: 354 -------------QQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNP 400 Query: 357 PSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQ 416 S GPP G Q P+G+ + T G ++ + + P G Sbjct: 401 YSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPS 460 Query: 417 QYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQPSSGQYPPPTVNMGQYYKPEQFN 476 YG Q P Q P P +P S P Q +QPS Q P +P Q Sbjct: 461 GYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQS--------QPPQLQ 512 Query: 477 GQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQDV 536 SS YSQ ++PP A YP P P S P SP Q Sbjct: 513 --------SSQPPYSQ-QPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQ 563 Query: 537 KPPFP-PDIKPNMSALPPPPANHNDE 561 +P P P +A P P + + + Sbjct: 564 QPQQPAPSTLSQQAAYPQPQSQQSQQ 589 Score = 66.2 bits (160), Expect = 2e-10 Identities = 117/474 (24%), Positives = 162/474 (34%), Gaps = 95/474 (20%) Query: 111 HQKSRQSDPPGKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTV 170 +Q+ QS PP QPP S S P H PY S Q T Q P S Sbjct: 500 YQQQPQSQPPQLQSSQPPYSQQPSQPP---HQQSPAPYPS--QQSTTQQHPQS------- 547 Query: 171 WGVTNTSQSQVLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPA 230 SQ P P P + P S Q QQ +S + P Sbjct: 548 ----QPPYSQPQAQSPYQQQQPQQPA--PSTLSQQAAYPQPQSQQ--SQQTAYSQQRFPP 599 Query: 231 QPYIQQSMYGRPNYPGSGGFGASYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAA 290 + Q +G + S S GG M + +R P+ + + + Sbjct: 600 PQELSQDSFG--SQASSAPSMTSSKGGQE---DMNLSLQSR-PSSLPDLSGSIDDLPMGT 653 Query: 291 AAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMGGSMNPAS 350 A + +T+ +++ Q Q+ P Q S F P P G S +P Sbjct: 654 EGALSPGVSTSGISSSQGEQS---------NPAQ---SPFSPHTSPHLPGIRGPSPSPV- 700 Query: 351 MAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPGE 410 G P + Q R +SP G +MP PRP S +I P + Sbjct: 701 -----------GSPASVAQSRSGPLSPAAVPGNQMP------PRPPSGQSDSIMHPSMNQ 743 Query: 411 PNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQPSSGQYPPPTVNMGQYY 470 + Q G + P P QY +P P L+ P QPS GQ MG Y Sbjct: 744 SSIA-QDRGYMQRNPQMP-QYSSPQPGSALS---------PRQPSGGQI---HTGMGSY- 788 Query: 471 KPEQFNGQNNTFSGSSYSNYSQGNVNRPP--RPVPVANYPHSPVPGNPTPPMTPGS---- 524 +Q + + G Y QG R P +P ANYP + + G P G Sbjct: 789 --QQNSMGSYGPQGGQYG--PQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQ 844 Query: 525 -SIPPY-------LSPSQDVKPPFPPDIKPNM-----SALPPPPANHNDELRLT 565 IPPY +S + P+ P++ NM S + PPP N + + T Sbjct: 845 PGIPPYGTLPPGRMSHASMGNRPYGPNM-ANMPPQVGSGMCPPPGGMNRKTQET 897 Score = 62.4 bits (150), Expect = 2e-09 Identities = 109/480 (22%), Positives = 164/480 (34%), Gaps = 87/480 (18%) Query: 117 SDPPGKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQP-PGSLSVVTTVWGVTN 175 S P ++P P +S +S+ + +DGS DS ++N+ P PG + T + Sbjct: 1167 STPHSQIPPLPGMSRSNSVGIQDAFNDGS---DSTFQKRNSMTPNPGYQPSMNT-----S 1218 Query: 176 TSQSQVLGNPMANANNPMN--PGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPY 233 ++ P + M PG +P S N G+ P +S AGP Sbjct: 1219 DMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDP--------YSRAAGPGLGN 1270 Query: 234 IQQSMYGRPNYPGSGGFGA--SYPG-GPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAA 290 + +M R +YP G + + PG GP G P P++ Sbjct: 1271 V--AMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSN--------------P 1314 Query: 291 AAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRG---PASMGGSMN 347 + + + Q+ Q D +Y +QF Q P G P+ Sbjct: 1315 DSGMYSPSRYPPQQQQQQQQRHD-----------SYGNQFSTQGTPSGSPFPSQQTTMYQ 1363 Query: 348 PASMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLPIQNIKRPY 407 G GPP ++ + P+ T + QQ P +PQ Q +P Sbjct: 1364 QQQQNYKRPMDGTYGPPAKRHEGEMYSV-PYSTGQGQPQQQQLPPAQPQPASQQQAAQPS 1422 Query: 408 PGEP---NYGNQQY-------------GPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMP 451 P + YGN GP +QFP Q G+ PP N P Q M Sbjct: 1423 PQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMG 1482 Query: 452 SQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPV---ANYP 508 + M Q +N N +GS+ + VNR + AN+ Sbjct: 1483 GPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHE 1542 Query: 509 HS-PVPGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPPPPANHNDELRLTFP 567 S P G PP P + +PP P PP S PPP+ N +++ P Sbjct: 1543 GSWPSHGTRQPPYGPSAPVPPMTRP--------PP------SNYQPPPSMQNHIPQVSSP 1588 Score = 57.0 bits (136), Expect = 9e-08 Identities = 118/461 (25%), Positives = 150/461 (32%), Gaps = 138/461 (29%) Query: 217 AGQQQQFSAKAGPAQPYIQQSMYGRPNYPGSGGFGASYPGGPNA--------------PA 262 AGQ+ + A GP QP ++ G + G GG GA GGP A PA Sbjct: 54 AGQESEGPA-VGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPA 112 Query: 263 ------------------GMGIPPHTR-----PPA-DFTQPAAAAAAAAVAAAAAT---- 294 G+G PPH+ PPA F QP + +A AAAAA Sbjct: 113 LNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQ 172 Query: 295 ATATATATVAALQETQNKDINQY-GPMG-------PTQAYNSQFMNQPG--PRGPASMGG 344 + +AALQ + Y GP P YNS + N+ P PA Sbjct: 173 HGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALS 232 Query: 345 SMNPASMAAGMTPSGMSGPPMGMNQPRPPGISP-----FGTHGQRMPQQTYPG-PRPQSL 398 S + +G + S PP + S FG G P G P+P + Sbjct: 233 SPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTAT 292 Query: 399 PIQN--IKRP--------YPGEPNYGNQQYGPNSQFP----------------------- 425 P N + P YPG G Q G + P Sbjct: 293 PTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGG 352 Query: 426 TQPGQYPAPNPPRPLTSPNYPGQRMPSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGS 485 Q + AP P P R P QPSS P MG+ +P+ + G N Sbjct: 353 AQQRSHHAPMSPGSSGGGGQPLARTP-QPSS-----PMDQMGK-MRPQPYGGTN------ 399 Query: 486 SYSNYSQGNVNRPPRPVPVANYPHSPVPGNPTP---PMTP-------------GSSIPPY 529 YSQ P P YP P G+ TP PMT IPPY Sbjct: 400 ---PYSQ-QQGPPSGPQQGHGYPGQPY-GSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPY 454 Query: 530 ------------LSPSQDVKPPFPPDIKPNMSALPPPPANH 558 +P + + P P +P S PP H Sbjct: 455 GQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPH 495 Score = 46.6 bits (109), Expect = 1e-04 Identities = 101/425 (23%), Positives = 145/425 (34%), Gaps = 61/425 (14%) Query: 128 PLSSMSSMKPTLSHSDGSFPYD------SVPWQQN--TNQPPGSLSVVTTVWGVTNTSQS 179 P+ M M+P G+ PY S P Q + QP GS + + +QS Sbjct: 383 PMDQMGKMRP--QPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQS 440 Query: 180 QVLGNPMANANNPMNPGGNPMASGMTTSNPGLN--SPQFAGQQQQFSAKAGPAQPYIQQS 237 + G P G P G P N SP QQ +S + P+ Q S Sbjct: 441 AMGGLSYTQQIPPYGQQG-PSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPS 499 Query: 238 MYGRPNYPGSGGFGASYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATATA 297 +P S P P + PP+++ P+ QP + A + +T Sbjct: 500 YQQQPQ---------SQP--PQLQSSQ--PPYSQQPS---QPPHQQSPAPYPSQQSTTQQ 543 Query: 298 TATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMGGSMNPASMAAGMTP 357 + Q Q P P + SQ P P+ S S P Sbjct: 544 HPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQ---QTAYSQQRFPPP 600 Query: 358 SGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLP-----IQNIKRPYPGEPN 412 +S G P ++ + G + RP SLP I ++ G + Sbjct: 601 QELSQDSFGSQASSAPSMT--SSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALS 658 Query: 413 YGNQQYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPS-----------QPSSGQYPP 461 G G +S Q PA +P P TSP+ PG R PS Q SG P Sbjct: 659 PGVSTSGISSSQGEQSN--PAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSP 716 Query: 462 PTVNMGQYYKPEQFNGQNNTFSGSSYSNYS----QGNVNRPPRPVPVANYPHSPVPGNPT 517 V G P +GQ+++ S + S +G + R P+ + Y SP PG+ Sbjct: 717 AAV-PGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQ---MPQY-SSPQPGSAL 771 Query: 518 PPMTP 522 P P Sbjct: 772 SPRQP 776 Score = 45.8 bits (107), Expect = 2e-04 Identities = 52/198 (26%), Positives = 70/198 (35%), Gaps = 20/198 (10%) Query: 839 GIPSKRFKTMSPSQMIMPNVMEMIAALGPGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGN 898 G P + + + +P + M +A+G G S PP G + Y QG + N Sbjct: 416 GYPGQPYGSQTPQRYPMTMQGRAQSAMG-GLSYTQQIPPYGQQGPSGYGQQGQT--PYYN 472 Query: 899 FDFPHGNPGGTSMNDFMHGPPQLSHPPDMPNNM--AALEKPLSHPMQETMPHAGSSDQPH 956 PH PP PP + + ++P S P Q S QP Sbjct: 473 QQSPHPQ---------QQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPS 523 Query: 957 PSIQQGLHVPHPSSQSGPPLHHSGAPP--PPPSQPP---RQPPQAAPSSHPHSDLTFNPS 1011 Q P+PS QS H PP P +Q P +QP Q APS+ P Sbjct: 524 QPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQ 583 Query: 1012 SALEGQAGAQGASDMPEP 1029 S + Q A P P Sbjct: 584 SQ-QSQQTAYSQQRFPPP 600 Score = 45.1 bits (105), Expect = 4e-04 Identities = 74/318 (23%), Positives = 98/318 (30%), Gaps = 46/318 (14%) Query: 258 PNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATATATATATVAALQETQNKDINQY 317 P +PAG G + P T + A A+ + + + + + I Sbjct: 1132 PPSPAGSGSMQGPQTPQS-TSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDA 1190 Query: 318 GPMGPTQAYNSQFMNQPGPRGPASMGGSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISP 377 G + + P P SMN + M M+ P M + PG P Sbjct: 1191 FNDGSDSTFQKRNSMTPNP----GYQPSMNTSDMMGRMSYEPNKDPYGSMR--KAPGSDP 1244 Query: 378 FGTHGQRMPQQTYPGPRP-QSLPIQNIKRPYPGEPNYGNQQY----GPNSQFPTQPGQYP 432 F + GQ GP P P G G +Q+ GP + T+PG P Sbjct: 1245 FMSSGQ--------GPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGP 1296 Query: 433 APNPPRPLTSPNYPGQRMPSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQ 492 N PN MPS P SG Y P Y P+Q Q +Q Sbjct: 1297 EGNMSTGAPQPNL----MPSNPDSGMYSP------SRYPPQQQQQQQQRHDSYGNQFSTQ 1346 Query: 493 GNVNRPPRPVPVA--------NYPHSPVPGNPTPPMTPGSS---IPPYLS----PSQDVK 537 G + P P NY P+ G PP PY + P Q Sbjct: 1347 GTPSGSPFPSQQTTMYQQQQQNYKR-PMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQL 1405 Query: 538 PPFPPDIKPNMSALPPPP 555 PP P A P P Sbjct: 1406 PPAQPQPASQQQAAQPSP 1423 Score = 43.5 bits (101), Expect = 0.001 Identities = 86/368 (23%), Positives = 126/368 (34%), Gaps = 44/368 (11%) Query: 119 PPGKLPMQPPLSSMSSMKPTLS-HSDGSFPYDSVPWQQNTNQPPGS-LSVVTTVWGVTNT 176 P G + P ++ P +S +P QQ + G+ S T G Sbjct: 1296 PEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFP 1355 Query: 177 SQSQVL-GNPMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYI- 234 SQ + N PM+ P A + P GQ Q + PAQP Sbjct: 1356 SQQTTMYQQQQQNYKRPMDGTYGPPAK--RHEGEMYSVPYSTGQGQPQQQQLPPAQPQPA 1413 Query: 235 --QQSMYGRPNYPGSGGFGASYPGGPNA-----PAGMGIPPHTRPPADFTQPAAAAAAAA 287 QQ+ P +G +YP A PAG P + P F + +A Sbjct: 1414 SQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAG---GPQNQFPFQFGRDRVSAPPGT 1470 Query: 288 VAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMGGSMN 347 A A+ + Q + Q G T Y ++ P+GPA G + Sbjct: 1471 NAQQNMPPQMMGGPIQASAEVAQQGTMWQ-GRNDMTYNYANRQSTGSAPQGPAYHGVNRT 1529 Query: 348 PASMAA-------GMTPS-GMSGPPMGMNQPRPPGISPFGTHGQ-------RMPQQTYPG 392 + G PS G PP G + P PP P ++ Q +PQ + P Sbjct: 1530 DEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPA 1589 Query: 393 PRPQSLPIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPPRP------LTSPNYP 446 P P+ P++N R P + + + P P + AP P +P +T P P Sbjct: 1590 PLPR--PMEN--RTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFP--P 1643 Query: 447 GQRMPSQP 454 G +QP Sbjct: 1644 GSVEATQP 1651 Score = 43.1 bits (100), Expect = 0.001 Identities = 66/290 (22%), Positives = 92/290 (31%), Gaps = 56/290 (19%) Query: 258 PNAPAGMGIPPHTRPP----ADFTQPAAAAAAAAVAAAAATATATATATVAALQETQNKD 313 P A + +G PP P A+ Q A AA AAAA A AA QE++ Sbjct: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKA----AAGQESEGPA 62 Query: 314 INQYGPMGPTQAYNSQFMNQPGPRGPASMGGS-----------------------MNPAS 350 + P+G ++ G G S GG P Sbjct: 63 VGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPG 122 Query: 351 MAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMP-----------QQTYPGPRPQSLP 399 G + G+ PP PP FG R P Q + G + L Sbjct: 123 GGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLA 182 Query: 400 IQNI-----KRPYPG------EPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQ 448 PY G + + N QY NS +P + YP P P L+SP Sbjct: 183 ALQSGGGGGLEPYAGPQQNSHDHGFPNHQY--NSYYPNR-SAYPPPAPAYALSSPRGGTP 239 Query: 449 RMPSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRP 498 + ++G PPP+ + F Q G + + G +P Sbjct: 240 GSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQP 289 Score = 39.7 bits (91), Expect = 0.015 Identities = 45/167 (26%), Positives = 54/167 (32%), Gaps = 31/167 (18%) Query: 866 GPGPSPYPLPPPP---------------GGTN--SNDYSSQGNNYQGHGNFDFPHGNPGG 908 G G P P P GGTN S QGHG P+G+ Sbjct: 368 GGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTP 427 Query: 909 TSMNDFMHGPPQ-----LSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGL 963 M G Q LS+ +P + P + Q P+ + PHP QQ Sbjct: 428 QRYPMTMQGRAQSAMGGLSYTQQIP--PYGQQGPSGYGQQGQTPYY-NQQSPHPQQQQ-- 482 Query: 964 HVPHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSHPHSDLTFNP 1010 P PP A P QP QPPQ S P+S P Sbjct: 483 ----PPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQP 525 Score = 35.8 bits (81), Expect = 0.22 Identities = 40/149 (26%), Positives = 55/149 (36%), Gaps = 30/149 (20%) Query: 873 PLPPPPGGTNSND---YSSQGNNYQG----HGNFDFPHGNPGGTSMNDFMHGPPQLSHPP 925 P P G N D ++ Q N++G HG P+G P P PP Sbjct: 1518 PQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYG-PSAPVPPMTRPPPSNYQPPP 1576 Query: 926 DMPNNMAALEKP--LSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSGAPP 983 M N++ + P L PM+ ++ PS LH ++GPP+ S P Sbjct: 1577 SMQNHIPQVSSPAPLPRPME---------NRTSPSKSPFLHSGMKMQKAGPPVPASHIAP 1627 Query: 984 PPPSQPPRQPPQAAPSSHPHSDLTFNPSS 1012 P QPP D+TF P S Sbjct: 1628 APV-----QPPMI------RRDITFPPGS 1645 Score = 30.8 bits (68), Expect = 7.1 Identities = 40/179 (22%), Positives = 54/179 (30%), Gaps = 20/179 (11%) Query: 841 PSKRFKTMSPSQMIMPNVMEMIAALGPGPSPYPLPPPPGGTNSNDY---SSQGNNYQGHG 897 PS S S + GP + P P N S YQG+ Sbjct: 253 PSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYP 312 Query: 898 NFDFPHGNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHP 957 D+ G G + GP ++ AA S Q+ HA S Sbjct: 313 GGDYSGGPQDGGAGK----GPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMS----- 363 Query: 958 SIQQGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEG 1016 P S G PL + P P Q + PQ ++P+S PS +G Sbjct: 364 --------PGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQG 414 >gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] Length = 2068 Score = 84.7 bits (208), Expect = 4e-16 Identities = 109/446 (24%), Positives = 144/446 (32%), Gaps = 77/446 (17%) Query: 120 PGKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWGVTNTSQS 179 P + PP + + LS G P + PP S + ++ +++S + Sbjct: 217 PNRSAYPPPAPAYA-----LSSPRGGTPGSGAAAAAGSKPPPSSSASASS----SSSSFA 267 Query: 180 QVLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQSMY 239 Q M GG P + T N L SP S Sbjct: 268 QQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPS---------------------SAR 306 Query: 240 GRPNYPGSGGFGASYPGGP-NAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATATAT 298 G YPG Y GGP + AG G PAD AAAAA AAAAA+ A Sbjct: 307 GYQGYPGG-----DYSGGPQDGGAGKG-------PADMASQCWGAAAAAAAAAAASGGA- 353 Query: 299 ATATVAALQETQNKDINQYGPMGPTQAYNS--QFMNQPGPRGPASMGGSMNPASMAAGMT 356 + + + PM P + P P P G M P Sbjct: 354 -------------QQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNP 400 Query: 357 PSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQ 416 S GPP G Q P+G+ + T G ++ + + P G Sbjct: 401 YSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPS 460 Query: 417 QYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQPSSGQYPPPTVNMGQYYKPEQFN 476 YG Q P Q P P +P S P Q +QPS Q P +P Q Sbjct: 461 GYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQS--------QPPQLQ 512 Query: 477 GQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQDV 536 SS YSQ ++PP A YP P P S P SP Q Sbjct: 513 --------SSQPPYSQ-QPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQ 563 Query: 537 KPPFP-PDIKPNMSALPPPPANHNDE 561 +P P P +A P P + + + Sbjct: 564 QPQQPAPSTLSQQAAYPQPQSQQSQQ 589 Score = 66.2 bits (160), Expect = 2e-10 Identities = 117/474 (24%), Positives = 162/474 (34%), Gaps = 95/474 (20%) Query: 111 HQKSRQSDPPGKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTV 170 +Q+ QS PP QPP S S P H PY S Q T Q P S Sbjct: 500 YQQQPQSQPPQLQSSQPPYSQQPSQPP---HQQSPAPYPS--QQSTTQQHPQS------- 547 Query: 171 WGVTNTSQSQVLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPA 230 SQ P P P + P S Q QQ +S + P Sbjct: 548 ----QPPYSQPQAQSPYQQQQPQQPA--PSTLSQQAAYPQPQSQQ--SQQTAYSQQRFPP 599 Query: 231 QPYIQQSMYGRPNYPGSGGFGASYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAA 290 + Q +G + S S GG M + +R P+ + + + Sbjct: 600 PQELSQDSFG--SQASSAPSMTSSKGGQE---DMNLSLQSR-PSSLPDLSGSIDDLPMGT 653 Query: 291 AAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMGGSMNPAS 350 A + +T+ +++ Q Q+ P Q S F P P G S +P Sbjct: 654 EGALSPGVSTSGISSSQGEQS---------NPAQ---SPFSPHTSPHLPGIRGPSPSPV- 700 Query: 351 MAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPGE 410 G P + Q R +SP G +MP PRP S +I P + Sbjct: 701 -----------GSPASVAQSRSGPLSPAAVPGNQMP------PRPPSGQSDSIMHPSMNQ 743 Query: 411 PNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQPSSGQYPPPTVNMGQYY 470 + Q G + P P QY +P P L+ P QPS GQ MG Y Sbjct: 744 SSIA-QDRGYMQRNPQMP-QYSSPQPGSALS---------PRQPSGGQI---HTGMGSY- 788 Query: 471 KPEQFNGQNNTFSGSSYSNYSQGNVNRPP--RPVPVANYPHSPVPGNPTPPMTPGS---- 524 +Q + + G Y QG R P +P ANYP + + G P G Sbjct: 789 --QQNSMGSYGPQGGQYG--PQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQ 844 Query: 525 -SIPPY-------LSPSQDVKPPFPPDIKPNM-----SALPPPPANHNDELRLT 565 IPPY +S + P+ P++ NM S + PPP N + + T Sbjct: 845 PGIPPYGTLPPGRMSHASMGNRPYGPNM-ANMPPQVGSGMCPPPGGMNRKTQET 897 Score = 57.0 bits (136), Expect = 9e-08 Identities = 118/461 (25%), Positives = 150/461 (32%), Gaps = 138/461 (29%) Query: 217 AGQQQQFSAKAGPAQPYIQQSMYGRPNYPGSGGFGASYPGGPNA--------------PA 262 AGQ+ + A GP QP ++ G + G GG GA GGP A PA Sbjct: 54 AGQESEGPA-VGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPA 112 Query: 263 ------------------GMGIPPHTR-----PPA-DFTQPAAAAAAAAVAAAAAT---- 294 G+G PPH+ PPA F QP + +A AAAAA Sbjct: 113 LNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQ 172 Query: 295 ATATATATVAALQETQNKDINQY-GPMG-------PTQAYNSQFMNQPG--PRGPASMGG 344 + +AALQ + Y GP P YNS + N+ P PA Sbjct: 173 HGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALS 232 Query: 345 SMNPASMAAGMTPSGMSGPPMGMNQPRPPGISP-----FGTHGQRMPQQTYPG-PRPQSL 398 S + +G + S PP + S FG G P G P+P + Sbjct: 233 SPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTAT 292 Query: 399 PIQN--IKRP--------YPGEPNYGNQQYGPNSQFP----------------------- 425 P N + P YPG G Q G + P Sbjct: 293 PTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGG 352 Query: 426 TQPGQYPAPNPPRPLTSPNYPGQRMPSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGS 485 Q + AP P P R P QPSS P MG+ +P+ + G N Sbjct: 353 AQQRSHHAPMSPGSSGGGGQPLARTP-QPSS-----PMDQMGK-MRPQPYGGTN------ 399 Query: 486 SYSNYSQGNVNRPPRPVPVANYPHSPVPGNPTP---PMTP-------------GSSIPPY 529 YSQ P P YP P G+ TP PMT IPPY Sbjct: 400 ---PYSQ-QQGPPSGPQQGHGYPGQPY-GSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPY 454 Query: 530 ------------LSPSQDVKPPFPPDIKPNMSALPPPPANH 558 +P + + P P +P S PP H Sbjct: 455 GQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPH 495 Score = 48.1 bits (113), Expect = 4e-05 Identities = 71/291 (24%), Positives = 88/291 (30%), Gaps = 82/291 (28%) Query: 334 PGPRGPASMGGSMNPASMAAGMTPSGMSGPPMGMNQPRP-----PGISPFGTHG------ 382 P P G SM G P S ++ M G PP + P PG+S + G Sbjct: 1133 PSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFN 1192 Query: 383 --------QRMPQQTYPGPRPQ--------SLPIQNIKRPY------PGE---------- 410 +R PG +P + + K PY PG Sbjct: 1193 DGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGP 1252 Query: 411 -------------PNYGNQQYGPNSQFP---------TQPGQYPAPNPPRPLTSPNYPGQ 448 P GN GP +P T+PG P N PN Sbjct: 1253 NGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNL--- 1309 Query: 449 RMPSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRP-VPVANY 507 MPS P SG Y P Y P+Q Q +QG + P P Y Sbjct: 1310 -MPSNPDSGMYSP------SRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMY 1362 Query: 508 PHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPPPPANH 558 +P P P + SPS K PF A PP PA+H Sbjct: 1363 QQQQQVSSPAPLPRP---MENRTSPS---KSPFLHSGMKMQKAGPPVPASH 1407 Score = 46.6 bits (109), Expect = 1e-04 Identities = 101/425 (23%), Positives = 145/425 (34%), Gaps = 61/425 (14%) Query: 128 PLSSMSSMKPTLSHSDGSFPYD------SVPWQQN--TNQPPGSLSVVTTVWGVTNTSQS 179 P+ M M+P G+ PY S P Q + QP GS + + +QS Sbjct: 383 PMDQMGKMRP--QPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQS 440 Query: 180 QVLGNPMANANNPMNPGGNPMASGMTTSNPGLN--SPQFAGQQQQFSAKAGPAQPYIQQS 237 + G P G P G P N SP QQ +S + P+ Q S Sbjct: 441 AMGGLSYTQQIPPYGQQG-PSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPS 499 Query: 238 MYGRPNYPGSGGFGASYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATATA 297 +P S P P + PP+++ P+ QP + A + +T Sbjct: 500 YQQQPQ---------SQP--PQLQSSQ--PPYSQQPS---QPPHQQSPAPYPSQQSTTQQ 543 Query: 298 TATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMGGSMNPASMAAGMTP 357 + Q Q P P + SQ P P+ S S P Sbjct: 544 HPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQ---QTAYSQQRFPPP 600 Query: 358 SGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLP-----IQNIKRPYPGEPN 412 +S G P ++ + G + RP SLP I ++ G + Sbjct: 601 QELSQDSFGSQASSAPSMT--SSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALS 658 Query: 413 YGNQQYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPS-----------QPSSGQYPP 461 G G +S Q PA +P P TSP+ PG R PS Q SG P Sbjct: 659 PGVSTSGISSSQGEQSN--PAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSP 716 Query: 462 PTVNMGQYYKPEQFNGQNNTFSGSSYSNYS----QGNVNRPPRPVPVANYPHSPVPGNPT 517 V G P +GQ+++ S + S +G + R P+ + Y SP PG+ Sbjct: 717 AAV-PGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQ---MPQY-SSPQPGSAL 771 Query: 518 PPMTP 522 P P Sbjct: 772 SPRQP 776 Score = 45.8 bits (107), Expect = 2e-04 Identities = 52/198 (26%), Positives = 70/198 (35%), Gaps = 20/198 (10%) Query: 839 GIPSKRFKTMSPSQMIMPNVMEMIAALGPGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGN 898 G P + + + +P + M +A+G G S PP G + Y QG + N Sbjct: 416 GYPGQPYGSQTPQRYPMTMQGRAQSAMG-GLSYTQQIPPYGQQGPSGYGQQGQT--PYYN 472 Query: 899 FDFPHGNPGGTSMNDFMHGPPQLSHPPDMPNNM--AALEKPLSHPMQETMPHAGSSDQPH 956 PH PP PP + + ++P S P Q S QP Sbjct: 473 QQSPHPQ---------QQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPS 523 Query: 957 PSIQQGLHVPHPSSQSGPPLHHSGAPP--PPPSQPP---RQPPQAAPSSHPHSDLTFNPS 1011 Q P+PS QS H PP P +Q P +QP Q APS+ P Sbjct: 524 QPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQ 583 Query: 1012 SALEGQAGAQGASDMPEP 1029 S + Q A P P Sbjct: 584 SQ-QSQQTAYSQQRFPPP 600 Score = 43.1 bits (100), Expect = 0.001 Identities = 66/290 (22%), Positives = 92/290 (31%), Gaps = 56/290 (19%) Query: 258 PNAPAGMGIPPHTRPP----ADFTQPAAAAAAAAVAAAAATATATATATVAALQETQNKD 313 P A + +G PP P A+ Q A AA AAAA A AA QE++ Sbjct: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKA----AAGQESEGPA 62 Query: 314 INQYGPMGPTQAYNSQFMNQPGPRGPASMGGS-----------------------MNPAS 350 + P+G ++ G G S GG P Sbjct: 63 VGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPG 122 Query: 351 MAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMP-----------QQTYPGPRPQSLP 399 G + G+ PP PP FG R P Q + G + L Sbjct: 123 GGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLA 182 Query: 400 IQNI-----KRPYPG------EPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQ 448 PY G + + N QY NS +P + YP P P L+SP Sbjct: 183 ALQSGGGGGLEPYAGPQQNSHDHGFPNHQY--NSYYPNR-SAYPPPAPAYALSSPRGGTP 239 Query: 449 RMPSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRP 498 + ++G PPP+ + F Q G + + G +P Sbjct: 240 GSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQP 289 Score = 39.7 bits (91), Expect = 0.015 Identities = 45/167 (26%), Positives = 54/167 (32%), Gaps = 31/167 (18%) Query: 866 GPGPSPYPLPPPP---------------GGTN--SNDYSSQGNNYQGHGNFDFPHGNPGG 908 G G P P P GGTN S QGHG P+G+ Sbjct: 368 GGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTP 427 Query: 909 TSMNDFMHGPPQ-----LSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGL 963 M G Q LS+ +P + P + Q P+ + PHP QQ Sbjct: 428 QRYPMTMQGRAQSAMGGLSYTQQIP--PYGQQGPSGYGQQGQTPYY-NQQSPHPQQQQ-- 482 Query: 964 HVPHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSHPHSDLTFNP 1010 P PP A P QP QPPQ S P+S P Sbjct: 483 ----PPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQP 525 Score = 36.2 bits (82), Expect = 0.17 Identities = 42/180 (23%), Positives = 61/180 (33%), Gaps = 39/180 (21%) Query: 833 IKDDPDGIPSKRFKTMSPSQMIMPNVMEMIAALGPGPSPYPLPPPPGGTNSNDYSSQGNN 892 ++ +P P T +P +MP+ + SP PP + S GN Sbjct: 1288 VRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMY-----SPSRYPPQQQQQQQQRHDSYGNQ 1342 Query: 893 YQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSS 952 + G P G+P + Q+S P PL PM+ Sbjct: 1343 FSTQGT---PSGSPFPSQQTTMYQQQQQVSSPA-----------PLPRPME--------- 1379 Query: 953 DQPHPSIQQGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSHPHSDLTFNPSS 1012 ++ PS LH ++GPP+ S P P QPP D+TF P S Sbjct: 1380 NRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPV-----QPPMI------RRDITFPPGS 1428 Score = 30.8 bits (68), Expect = 7.1 Identities = 40/179 (22%), Positives = 54/179 (30%), Gaps = 20/179 (11%) Query: 841 PSKRFKTMSPSQMIMPNVMEMIAALGPGPSPYPLPPPPGGTNSNDY---SSQGNNYQGHG 897 PS S S + GP + P P N S YQG+ Sbjct: 253 PSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYP 312 Query: 898 NFDFPHGNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHP 957 D+ G G + GP ++ AA S Q+ HA S Sbjct: 313 GGDYSGGPQDGGAGK----GPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMS----- 363 Query: 958 SIQQGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEG 1016 P S G PL + P P Q + PQ ++P+S PS +G Sbjct: 364 --------PGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQG 414 >gi|7706637 protein inhibitor of activated STAT, 1 [Homo sapiens] Length = 651 Score = 82.8 bits (203), Expect = 2e-15 Identities = 90/369 (24%), Positives = 151/369 (40%), Gaps = 54/369 (14%) Query: 499 PRPVPVANYPHSPVPGNPTPPMTP-----GSSIPPYLSPSQDVKPPFPPDIKPNMSALPP 553 P + + N SP+P +P P G L P + P ++ SAL P Sbjct: 72 PADLSIPNVHSSPMPATLSPSTIPQLTYDGHPASSPLLPVSLLGPKHELELPHLTSALHP 131 Query: 554 PPANHNDELRLTFPVRDGVVLEPFRLEHNLAVSNH--------VFHLRPTVHQTLMWRSD 605 H D P D +L+ +LA N F L P Q + D Sbjct: 132 V---HPDIKLQKLPFYD--LLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQISSSMD 186 Query: 606 L-----------ELQFKCYHHEDRQMNTNWPASVQVSVNATPLTI-------ERG-DNKT 646 + +L+F C ++P ++ V VN P ++ + G + K Sbjct: 187 ISGTKCDFTVQVQLRF-CLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKR 245 Query: 647 SHKPLHLKHVCQPGR---NTIQITVTA-CCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPA 702 +P+++ + + NTI ++ TA ++ + LV + S +LQ L K + Sbjct: 246 PSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAKGIRNP 305 Query: 703 EHCITKIKRNFSSVAASSGNTTLNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCKHVQ 762 +H IK T + + + T+++VSL CP+ R+ +P R C H+Q Sbjct: 306 DHSRALIKEKL----------TADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQ 355 Query: 763 CFDLESYLQLNCERGTWRCPVCNKTALLEGLEVDQYMWGILNAIQHSEFEEVTIDPTCSW 822 CFD Y+Q+N ++ TW CPVC+K A E L +D IL ++ +E+ +W Sbjct: 356 CFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYC--TDCDEIQFKEDGTW 413 Query: 823 RPVPIKSDL 831 P+ K ++ Sbjct: 414 APMRSKKEV 422 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 77.4 bits (189), Expect = 7e-14 Identities = 104/381 (27%), Positives = 130/381 (34%), Gaps = 51/381 (13%) Query: 213 SPQFAGQQQQFSAKAGPAQPYIQQSMYGRPNYPGSGGFGASYPGGPNAPAG--MGIPPHT 270 SP Q + G +P S G+P P G + P GP P G G PP Sbjct: 28 SPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQG--GNQPQGPPPPPGKPQGPPPQG 85 Query: 271 -RPPADFTQPAAAAAAAAVAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQ 329 P P + + + + N+ P G Q Q Sbjct: 86 GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 145 Query: 330 FMNQPG-------PRGPASMGGSMNPASMAAGMTPSGMSGPPMGMNQPR---PPGISPFG 379 N+P P+GP G + + +S + P G PP G NQP+ PP P G Sbjct: 146 GGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGP--PPQGGNQPQGPPPPPGKPQG 203 Query: 380 T--HGQRMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPP 437 G PQ P +PQ P Q + G Q GP Q QP Q P P P Sbjct: 204 PPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQ-GPPPQGGNQP-QGPPPPPG 261 Query: 438 RPLTSPNYPGQRM--PSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQG-- 493 +P P G + P P Q PPP G + + S S QG Sbjct: 262 KPQGPPPQGGNKPQGPPPPGKPQGPPP-------------QGGSKSRSSRSPPGKPQGPP 308 Query: 494 --NVNRPPRPVPVANYPHSPVP--GN----PTPPMTPGSSIPPYLSPSQDV-----KPPF 540 N+P P P P P P GN P PP P P S S+ KP Sbjct: 309 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQG 368 Query: 541 PPDIKPNMSALPPPPANHNDE 561 PP + N PPPPA N + Sbjct: 369 PPQQEGNNPQGPPPPAGGNPQ 389 Score = 67.0 bits (162), Expect = 9e-11 Identities = 109/405 (26%), Positives = 127/405 (31%), Gaps = 93/405 (22%) Query: 183 GNPMANANNPMNPGGNPMASGMTTSNP--GLNSPQFAGQQQQFSAKAGPAQPYIQQSMYG 240 G P N P P P G P G N PQ G + P Q +S Sbjct: 59 GPPPQGGNQPQGP---PPPPGKPQGPPPQGGNKPQ--GPPPPGKPQGPPPQGDKSRSPRS 113 Query: 241 RPNYP-GSGGFGASYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATATATA 299 P P G G + P GP P G P PP +P Sbjct: 114 PPGKPQGPPPQGGNQPQGPPPPPGK---PQGPPPQGGNKPQGPPPPGKPQGPPP------ 164 Query: 300 TATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPG--------PRGPASMGGSMN---- 347 + NK + P G Q Q NQP P+GP GG+ Sbjct: 165 --------QGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 216 Query: 348 PASMAAGMTPSG--------------MSGPPMGMNQPR---PPGISPFGT--HGQRMPQQ 388 P G P G PP G NQP+ PP P G G PQ Sbjct: 217 PPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 276 Query: 389 TYPGPRPQSLPIQN-----IKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTSP 443 P +PQ P Q R PG+P GP Q QP Q P P P +P P Sbjct: 277 PPPPGKPQGPPPQGGSKSRSSRSPPGKPQ------GPPPQGGNQP-QGPPPPPGKPQGPP 329 Query: 444 NYPGQRM--PSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRP 501 G + P P Q PPP G + + S S QG PP+ Sbjct: 330 PQGGNKPQGPPPPGKPQGPPP-------------QGGSKSRSARSPPGKPQG----PPQ- 371 Query: 502 VPVANYPHSPVP---GNPTPPMTPGSSIPP-YLSPSQDVKPPFPP 542 N P P P GNP P P + P P Q +P PP Sbjct: 372 -QEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 415 Score = 45.1 bits (105), Expect = 4e-04 Identities = 43/154 (27%), Positives = 50/154 (32%), Gaps = 30/154 (19%) Query: 866 GPGPSPYPLPPPPGGTNSNDYSSQ------------GNNYQGHGNFDFPHGNPGGTSMN- 912 GP P P PPP G N + + GN QG P G P G Sbjct: 214 GPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPP---PPGKPQGPPPQG 270 Query: 913 -DFMHGPPQLSHPPDMPNNMAALEKPLSHPM---QETMPHAGSSDQPHPSIQQGLHVPHP 968 + GPP P P + + P Q P G+ Q P P P Sbjct: 271 GNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPP--------PPP 322 Query: 969 SSQSGPPLHHSGAP--PPPPSQPPRQPPQAAPSS 1000 GPP P PPPP +P PPQ S Sbjct: 323 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKS 356 Score = 42.4 bits (98), Expect = 0.002 Identities = 43/140 (30%), Positives = 48/140 (34%), Gaps = 22/140 (15%) Query: 875 PPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPP-QLSHPPDMPNNMAA 933 PPPP G GN QG P G P + PP + PP N Sbjct: 71 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQ 130 Query: 934 LEKPLSHPMQETMPHAGSSDQ--PHPSIQQGLHVPHP-------SSQS------GPPLHH 978 P Q P G+ Q P P QG P P SS+S GPP Sbjct: 131 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG---PPPQGDNKSRSSRSPPGKPQGPPPQG 187 Query: 979 SG---APPPPPSQPPRQPPQ 995 PPPPP +P PPQ Sbjct: 188 GNQPQGPPPPPGKPQGPPPQ 207 Score = 41.6 bits (96), Expect = 0.004 Identities = 45/162 (27%), Positives = 50/162 (30%), Gaps = 37/162 (22%) Query: 875 PPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNP--GGTSMNDFMHGPPQLSHPPDMPNNMA 932 PPPP G GN QG P G P GG+ P + PP N Sbjct: 256 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQP 315 Query: 933 ALEKPLSHPMQETMPHAGSSDQ--PHPSIQQGLHVPHPSSQS-------------GPPLH 977 P Q P G+ Q P P QG P P S GPP Sbjct: 316 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG---PPPQGGSKSRSARSPPGKPQGPPQQ 372 Query: 978 HSGAP--PPPPS---------------QPPRQPPQAAPSSHP 1002 P PPPP+ Q P +PPQ S P Sbjct: 373 EGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 414 Score = 41.2 bits (95), Expect = 0.005 Identities = 40/131 (30%), Positives = 45/131 (34%), Gaps = 33/131 (25%) Query: 904 GNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGL 963 GNP G PPQ + P P + KP P P G+ Q P Sbjct: 34 GNPQGA--------PPQGGNKPQGPPSPPG--KPQGPP-----PQGGNQPQGPP------ 72 Query: 964 HVPHPSSQSGPPLHHSGAP--PPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEG---QA 1018 P P GPP P PPPP +P PPQ S P S P +G Q Sbjct: 73 --PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS-----PPGKPQGPPPQG 125 Query: 1019 GAQGASDMPEP 1029 G Q P P Sbjct: 126 GNQPQGPPPPP 136 Score = 38.9 bits (89), Expect = 0.026 Identities = 46/179 (25%), Positives = 54/179 (30%), Gaps = 23/179 (12%) Query: 866 GPGPSPYPLPPPPGGTNSNDYSS------QGNNYQGHGNFDFPHGNPGGTSMNDFMHGPP 919 GP P P PPP G N + S QG QG P PG PP Sbjct: 152 GPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ-----GPPP 206 Query: 920 QLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHS 979 Q + P P + P ++ +P QG + P PP Sbjct: 207 QGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGN--QPQGPPPPPGKPQ 264 Query: 980 GAP---------PPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEGQAGAQGASDMPEP 1029 G P PPPP +P PPQ S P Q G Q P P Sbjct: 265 GPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGP-PPQGGNQPQGPPPPP 322 Score = 38.1 bits (87), Expect = 0.045 Identities = 33/123 (26%), Positives = 39/123 (31%), Gaps = 26/123 (21%) Query: 875 PPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNP--GGTSMNDFMHGPPQLSHPPDMPNNMA 932 PPPP G GN QG P G P GG+ P + PP N Sbjct: 318 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGN-- 375 Query: 933 ALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQ 992 +P P G+ QP Q+ P G P PP P + Sbjct: 376 -------NPQGPPPPAGGNPQQP---------------QAPPAGQPQGPPRPPQGGRPSR 413 Query: 993 PPQ 995 PPQ Sbjct: 414 PPQ 416 Score = 37.0 bits (84), Expect = 0.099 Identities = 49/174 (28%), Positives = 53/174 (30%), Gaps = 37/174 (21%) Query: 867 PGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMN--DFMHGPPQLSHP 924 P P P PPP G GN QG P G P G + GPP P Sbjct: 51 PSPPGKPQGPPPQG---------GNQPQGPPP---PPGKPQGPPPQGGNKPQGPPPPGKP 98 Query: 925 PDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSGAP-- 982 P P S P + P +QP QG P P PP G P Sbjct: 99 QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP-----QG---PPP-----PPGKPQGPPPQ 145 Query: 983 -------PPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEGQAGAQGASDMPEP 1029 PPPP +P PPQ S P Q G Q P P Sbjct: 146 GGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGP-PPQGGNQPQGPPPPP 198 Score = 37.0 bits (84), Expect = 0.099 Identities = 46/178 (25%), Positives = 53/178 (29%), Gaps = 22/178 (12%) Query: 866 GPGPSPYPLPPPPGGTNSNDYSS-----QGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQ 920 GP P P PPP G S S QG QG P PG PPQ Sbjct: 91 GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ-----GPPPQ 145 Query: 921 LSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSG 980 + P P + P ++ +P QG + P PP G Sbjct: 146 GGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGN--QPQGPPPPPGKPQG 203 Query: 981 AP---------PPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEGQAGAQGASDMPEP 1029 P PPPP +P PPQ S P Q G Q P P Sbjct: 204 PPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGP-PPQGGNQPQGPPPPP 260 >gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 preproprotein [Homo sapiens] Length = 331 Score = 72.8 bits (177), Expect = 2e-12 Identities = 86/303 (28%), Positives = 109/303 (35%), Gaps = 46/303 (15%) Query: 300 TATVAALQETQN--KDINQY--------GPMGPTQAYNSQFMNQPGP----RGPASMGGS 345 + + AL QN +D++Q P GP+ ++ P P +GP GG+ Sbjct: 7 SVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGN 66 Query: 346 MN----PASMAAGMTPSG-------------MSGPPMGMNQPR---PPGISPFGT--HGQ 383 P G P G PP G NQP+ PP P G G Sbjct: 67 KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 126 Query: 384 RMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTSP 443 PQ P +PQ P Q K P P + GP Q QP Q P P P +P P Sbjct: 127 NRPQGPPPPGKPQGPPPQGDKSRSPRSPP--GKPQGPPPQGGNQP-QGPPPPPGKPQGPP 183 Query: 444 NYPGQRM--PSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRP 501 G++ P P Q PPP + + + Q G + +P P Sbjct: 184 PQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 243 Query: 502 VPVA-NYPHSPVP-GNPT-PPMTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPPPPANH 558 P N P P P G P PP GS SP KP PP + N PPPPA Sbjct: 244 PPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPG--KPQGPPQQEGNNPQGPPPPAGG 301 Query: 559 NDE 561 N + Sbjct: 302 NPQ 304 Score = 63.5 bits (153), Expect = 1e-09 Identities = 72/242 (29%), Positives = 85/242 (35%), Gaps = 26/242 (10%) Query: 319 PMGPTQAYNSQFMNQPGP----RGPASMGGSMNPASMAAGMTPSGMSGPPMG--MNQPRP 372 P GP +Q P P +GP GG+ G P G PP G PR Sbjct: 97 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGK-PQGP--PPQGDKSRSPRS 153 Query: 373 PGISPFGT--HGQRMPQQTYPGP-RPQSLPIQNIKRPY----PGEPNYGNQQYGPNSQFP 425 P P G G PQ P P +PQ P Q K+P PG+P G G S+ Sbjct: 154 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQ-GPPPQGDKSRSS 212 Query: 426 TQPGQYPAPNPPRPLTSPNYPGQRMPSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGS 485 P P PP+ P P P P Q PPP P Q G Sbjct: 213 QSPPGKPQGPPPQGGNQPQGP----PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGG 268 Query: 486 SYSNYSQGNVNRPP-RPVPVANYPHSPVP---GNPTPPMTPGSSIPP-YLSPSQDVKPPF 540 S S ++ +P P N P P P GNP P P + P P Q +P Sbjct: 269 SKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSR 328 Query: 541 PP 542 PP Sbjct: 329 PP 330 Score = 48.5 bits (114), Expect = 3e-05 Identities = 52/179 (29%), Positives = 58/179 (32%), Gaps = 43/179 (24%) Query: 861 MIAALGPGPSPY-----PLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFM 915 +IA GPSP PPPP G GN QG P G P G Sbjct: 31 LIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP----PPGKPQG------- 79 Query: 916 HGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPP 975 PP + + P P Q P G+ Q P P P GPP Sbjct: 80 --------PPPQGDKSRSPRSPPGKP-QGPPPQGGNQPQGPP--------PPPGKPQGPP 122 Query: 976 LHHSGAP--PPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEG---QAGAQGASDMPEP 1029 P PPPP +P PPQ S P S P +G Q G Q P P Sbjct: 123 PQGGNRPQGPPPPGKPQGPPPQGDKSRSPRS-----PPGKPQGPPPQGGNQPQGPPPPP 176 Score = 47.0 bits (110), Expect = 1e-04 Identities = 54/179 (30%), Positives = 59/179 (32%), Gaps = 26/179 (14%) Query: 866 GPGPSPYPLPPPPGGTNSNDYSSQGNNYQGH----GNFDF----PHGNPGGTSMN--DFM 915 GP P P PPP G S S QG GN P G P G + Sbjct: 70 GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRP 129 Query: 916 HGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPP 975 GPP P P P S P + P +QP QG P P GPP Sbjct: 130 QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP-----QG-PPPPPGKPQGPP 183 Query: 976 LHHSGAP--PPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEG---QAGAQGASDMPEP 1029 P PPPP +P PPQ S S P +G Q G Q P P Sbjct: 184 PQGGKKPQGPPPPGKPQGPPPQGDKSRSSQS-----PPGKPQGPPPQGGNQPQGPPPPP 237 Score = 43.1 bits (100), Expect = 0.001 Identities = 44/150 (29%), Positives = 50/150 (33%), Gaps = 24/150 (16%) Query: 866 GPGPSPYPLPPPPGGTNSNDYSSQGNNYQGH----GNFDF----PHGNPGGTSMNDFM-- 915 GP P P PPP G S S QG GN P G P G Sbjct: 131 GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKP 190 Query: 916 HGPP---QLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQS 972 GPP + PP + + + P P Q P G+ Q P P P Sbjct: 191 QGPPPPGKPQGPPPQGDKSRSSQSPPGKP-QGPPPQGGNQPQGPP--------PPPGKPQ 241 Query: 973 GPPLHHSGAP--PPPPSQPPRQPPQAAPSS 1000 GPP P PPPP +P P Q S Sbjct: 242 GPPPQGGNKPQGPPPPGKPQGPPAQGGSKS 271 Score = 40.4 bits (93), Expect = 0.009 Identities = 39/143 (27%), Positives = 49/143 (34%), Gaps = 11/143 (7%) Query: 866 GPGPSPYPLPPPPGGTNSNDYSS-----QGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQ 920 GP P P PPP G S S QG QG P PG PPQ Sbjct: 192 GPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQ-----GPPPQ 246 Query: 921 LSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPH-PSIQQGLHVPHPSSQSGPPLHHS 979 + P P + P + ++ +P P Q+G + P +G Sbjct: 247 GGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP 306 Query: 980 GAPPPPPSQPPRQPPQAAPSSHP 1002 APP Q P +PPQ S P Sbjct: 307 QAPPAGQPQGPPRPPQGGRPSRP 329 Score = 38.1 bits (87), Expect = 0.045 Identities = 33/123 (26%), Positives = 39/123 (31%), Gaps = 26/123 (21%) Query: 875 PPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNP--GGTSMNDFMHGPPQLSHPPDMPNNMA 932 PPPP G GN QG P G P GG+ P + PP N Sbjct: 233 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGN-- 290 Query: 933 ALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQ 992 +P P G+ QP Q+ P G P PP P + Sbjct: 291 -------NPQGPPPPAGGNPQQP---------------QAPPAGQPQGPPRPPQGGRPSR 328 Query: 993 PPQ 995 PPQ Sbjct: 329 PPQ 331 Score = 37.4 bits (85), Expect = 0.076 Identities = 33/116 (28%), Positives = 43/116 (37%), Gaps = 20/116 (17%) Query: 921 LSHPPDMPNNMAALEKP--LSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHH 978 LS ++ +++ E P ++ Q P G+ Q P P P GPP Sbjct: 13 LSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPP--------PPPGKPQGPPPQG 64 Query: 979 SGAP--PPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEG---QAGAQGASDMPEP 1029 P PPPP +P PPQ S P S P +G Q G Q P P Sbjct: 65 GNKPQGPPPPGKPQGPPPQGDKSRSPRS-----PPGKPQGPPPQGGNQPQGPPPPP 115 >gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo sapiens] Length = 309 Score = 70.5 bits (171), Expect = 8e-12 Identities = 76/241 (31%), Positives = 89/241 (36%), Gaps = 38/241 (15%) Query: 333 QPG-PRGPASMGGSMNPASMAAGMTPSGMSGPPMGMNQ---PRPPGISPFGTHGQRMPQQ 388 +PG P GP GG+ + P G PP G NQ P P P G Q Q Sbjct: 74 RPGKPEGPPPQGGNQSQGPPPRPGKPEGQ--PPQGGNQSQGPPPRPGKPEGPPPQGGNQS 131 Query: 389 TYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTS---PNY 445 P PRP +P P GNQ GP P +PG+ P P S P + Sbjct: 132 QGPPPRPG--------KPEGPPPQGGNQSQGP----PPRPGKPEGPPPQGGNQSQGPPPH 179 Query: 446 PGQRMPSQPSSG---QYPPPTVNMGQYYKPEQFNGQNNT--FSGSSYSNYSQGNVNRPPR 500 PG+ P G Q PPP + P+ N G SQG N+P Sbjct: 180 PGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGG-NKPQG 238 Query: 501 PVPVANYPHSPVP--GN----PTPPMTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPPP 554 P P P P P GN P PP P PP +P Q + PP P PPP Sbjct: 239 PPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGP-----PPP 293 Query: 555 P 555 P Sbjct: 294 P 294 Score = 58.5 bits (140), Expect = 3e-08 Identities = 78/330 (23%), Positives = 102/330 (30%), Gaps = 52/330 (15%) Query: 155 QNTNQPPGSLSVVTTVWGVTNTSQSQVLGNPMANANNPMNPGGNPMASGMTTSNPGLN-- 212 Q+ N+ + + G + Q P P P G P G + P Sbjct: 17 QSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPG 76 Query: 213 ---SPQFAGQQQQFSAKAGPAQPYIQQSMYGRPNYPGSGGFGAS-YPGGPNAPAGMGIPP 268 P G Q P +P G+P G+ G PG P P G Sbjct: 77 KPEGPPPQGGNQSQGPPPRPGKPE------GQPPQGGNQSQGPPPRPGKPEGPPPQGGNQ 130 Query: 269 HTRPPADFTQPAAAAAAAAVAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNS 328 PP +P ++Q P GP + Sbjct: 131 SQGPPPRPGKPEGPPPQGG-------------------NQSQGPPPRPGKPEGPPPQGGN 171 Query: 329 QFMNQPG----PRGPASMGGSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQR 384 Q P P GP GG+ + P G PP G NQ + P P G Sbjct: 172 QSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGP--PPQGGNQSQGPPPRPGKPEGP- 228 Query: 385 MPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTSPN 444 P Q G +PQ P P+PG+P Q G Q P PG+ P PP Sbjct: 229 -PSQG--GNKPQGPP------PHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPG-----G 274 Query: 445 YPGQRMPSQPSSGQYPPPTVNMGQYYKPEQ 474 P Q +P Q PPP G+ ++P Q Sbjct: 275 NPQQPLPPPAGKPQGPPPPPQGGRPHRPPQ 304 Score = 57.0 bits (136), Expect = 9e-08 Identities = 73/252 (28%), Positives = 85/252 (33%), Gaps = 56/252 (22%) Query: 336 PRGPASMGGSMNPASMAAGMTPSGMSGPPMGMNQ---PRPPGISPFGTHGQRMPQQTYPG 392 P G GG+ + P G PP G NQ P P P G Q Q P Sbjct: 36 PEGRRPQGGNQPQRTPPPPGKPEGR--PPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPP 93 Query: 393 PRPQSLPIQNIKRPYPGEPNYGNQQYGPNSQFPTQPG-------------QYPAPNPPRP 439 PRP +P P GNQ GP P +PG Q P P P +P Sbjct: 94 PRPG--------KPEGQPPQGGNQSQGP----PPRPGKPEGPPPQGGNQSQGPPPRPGKP 141 Query: 440 LTSPNYPG---QRMPSQPSSGQYPPPTV-NMGQYYKPEQFNGQNNTFSGSSYSNYSQGNV 495 P G Q P +P + PPP N Q P + G GN Sbjct: 142 EGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQG--------GNQ 193 Query: 496 NRPPRPVPVANYPHSPVP--GNPT--PPMTPG--------SSIPPYLSPSQDVKPPFPPD 543 ++ P P P P P P GN + PP PG P P KP PP Sbjct: 194 SQGPPPRP--GKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPP 251 Query: 544 IKPNMSALPPPP 555 + N PPPP Sbjct: 252 QEGNKPQRPPPP 263 Score = 52.8 bits (125), Expect = 2e-06 Identities = 64/238 (26%), Positives = 76/238 (31%), Gaps = 60/238 (25%) Query: 319 PMGPTQAYNSQFMNQPG----PRGPASMGGSMNPASMAAGMTPSGMSGPPMGMNQ---PR 371 P GP +Q P P GP GG+ + P G PP G NQ P Sbjct: 120 PEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGP--PPQGGNQSQGPP 177 Query: 372 PPGISPFGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQY 431 P P G Q Q P PRP +P P GNQ GP + P +P Sbjct: 178 PHPGKPEGPPPQGGNQSQGPPPRPG--------KPEGPPPQGGNQSQGPPPR-PGKPEGP 228 Query: 432 PAPNPPRPLTSPNYPGQRMPSQPSSG---QYPPPTVNMGQYYKPEQFNGQNNTFSGSSYS 488 P+ +P P +PG+ P G Q PPP Sbjct: 229 PSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPP------------------------- 263 Query: 489 NYSQGNVNRPPRPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDIKP 546 G PP P P P G P P PP P Q +P PP +P Sbjct: 264 ----GRPQGPPPPGGNPQQPLPPPAGKPQGP-------PP---PPQGGRPHRPPQGQP 307 Score = 46.2 bits (108), Expect = 2e-04 Identities = 48/170 (28%), Positives = 52/170 (30%), Gaps = 41/170 (24%) Query: 868 GPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPP-----QLS 922 G P PPPPG +G QG P PG GPP Q Sbjct: 44 GNQPQRTPPPPG-------KPEGRPPQGGNQSQGPPPRPGKPE------GPPPQGGNQSQ 90 Query: 923 HPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPL---HHS 979 PP P KP P P G+ Q P P P GPP + S Sbjct: 91 GPPPRPG------KPEGQP-----PQGGNQSQGPP--------PRPGKPEGPPPQGGNQS 131 Query: 980 GAPPPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEGQAGAQGASDMPEP 1029 PPP P +P PPQ S P Q G Q P P Sbjct: 132 QGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGP-PPQGGNQSQGPPPHP 180 Score = 44.7 bits (104), Expect = 5e-04 Identities = 44/144 (30%), Positives = 53/144 (36%), Gaps = 24/144 (16%) Query: 868 GPSPYPL----PPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSH 923 GP P+P PPP GG S + +G P G S GPP Sbjct: 175 GPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEG------PPPQGGNQSQ-----GPPPRPG 223 Query: 924 PPDMPNNMAALEK--PLSHP--MQETMPHAGSSDQ--PHPSIQQGLHVP--HPSSQSGPP 975 P+ P + + P HP Q P G+ Q P P QG P +P PP Sbjct: 224 KPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPP 283 Query: 976 LHH-SGAPPPPPSQPPRQPPQAAP 998 G PPPP P +PPQ P Sbjct: 284 AGKPQGPPPPPQGGRPHRPPQGQP 307 Score = 43.1 bits (100), Expect = 0.001 Identities = 67/279 (24%), Positives = 84/279 (30%), Gaps = 61/279 (21%) Query: 192 PMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFS--AKAGPAQPYIQQSMYGRPNYPGSGG 249 P P G P G + P + GQ Q ++ P +P G+P P G Sbjct: 75 PGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRP-------GKPEGPPPQG 127 Query: 250 FGASY-----PGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATATATATATVA 304 S PG P P G PP +P Sbjct: 128 GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGG----------------- 170 Query: 305 ALQETQNKDINQYGPMGPTQAYNSQFMNQPG----PRGPASMGGSMNPASMAAGMTPSGM 360 ++Q + P GP +Q P P GP GG+ S P Sbjct: 171 --NQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQ---SQGPPPRPGKP 225 Query: 361 SGPP-MGMNQPRPPGISPFGTHGQ-----RMPQQTYPGPRPQSLPIQNIKRPYPGEPNYG 414 GPP G N+P+ P P G PQ+ P RPQ P P G Sbjct: 226 EGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPP-----------PPGG 274 Query: 415 NQQYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQ 453 N P P G+ P PP P+ P Q P Q Sbjct: 275 N----PQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPPQ 309 Score = 42.7 bits (99), Expect = 0.002 Identities = 51/183 (27%), Positives = 59/183 (32%), Gaps = 40/183 (21%) Query: 866 GPGPSP-YPLPPPPGGTNSNDY------SSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGP 918 GP P P P PPP G N + +G QG P +PG GP Sbjct: 133 GPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPE------GP 186 Query: 919 P-----QLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVP-----HP 968 P Q PP P + Q P G + P PS QG + P HP Sbjct: 187 PPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGP-PS--QGGNKPQGPPPHP 243 Query: 969 SSQSGPPLHHSGAP-----------PPPPSQPPRQ---PPQAAPSSHPHSDLTFNPSSAL 1014 GPP P PPPP P+Q PP P P P Sbjct: 244 GKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPP 303 Query: 1015 EGQ 1017 +GQ Sbjct: 304 QGQ 306 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 69.7 bits (169), Expect = 1e-11 Identities = 94/375 (25%), Positives = 126/375 (33%), Gaps = 52/375 (13%) Query: 189 ANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQSMYGRPNYPGSG 248 A P +P G+P A+ + P + S K GPA P S+ G P P + Sbjct: 1037 AATPPSPKGSPAATPLPKGAPTTPAATLP------SPKGGPATP----SLKGAPTPPAAT 1086 Query: 249 GFGASYPGGPNAPAGMG--IPPHTRPPADFTQPAAAAAAAAVAAAAATATATATATVAAL 306 S GGP P+ G +PP PP+ P A A T AT + L Sbjct: 1087 P--PSPKGGPATPSPKGAPMPPAATPPS----PKGGLATPPHKGAPTTPAATPPSPKGGL 1140 Query: 307 QETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMGGSMNPASMAAGMTPSGMSGPPMG 366 K PT P P+ GG P A TP+ P G Sbjct: 1141 ATPPPKG-------APTT---------PAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1184 Query: 367 -MNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGPNSQFP 425 + P P G P+ P P+ P P P G P Sbjct: 1185 GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP--TTPAATPPSPKGGLATPSPKGAPT 1242 Query: 426 TQPGQYPAPNPPRPLTSPNYPGQR-MPSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSG 484 T PA PP P P P + P+ P++ PP++ G P + + Sbjct: 1243 T-----PAATPPSPKGGPATPPPKGAPTPPAA---TPPSLKGGLATPPHKGAPNPAVVTP 1294 Query: 485 SSYSNYSQGNVNRPPR--PVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPPFPP 542 S G PP+ P P A P SP G+P P G+ PP ++P P P Sbjct: 1295 PSPKG---GPATSPPKGAPTPPAATPPSP-KGSPGTPPPKGAPTPPAVTPPSPKGTPTLP 1350 Query: 543 DIKPNMSALPPPPAN 557 P+ P P++ Sbjct: 1351 ATTPSSKGGPTTPSS 1365 Score = 62.8 bits (151), Expect = 2e-09 Identities = 96/389 (24%), Positives = 132/389 (33%), Gaps = 58/389 (14%) Query: 183 GNPMANANNPMNPGGN---PMASGMTTSNPGLNSPQFAGQQQQFSAKAGP----AQPYIQ 235 G P A P +P G P G T+ P P G S K P A P Sbjct: 1147 GAPTTPAATPPSPKGGLATPPPKGAPTT-PAATPPSPKGGLATPSPKGAPTTPAATPPSP 1205 Query: 236 QSMYGRPNYPGSGGFGASYP----GGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAA 291 + P+ G+ A+ P GG P+ G P T P A P A A Sbjct: 1206 KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP--TTPAATPPSPKGGPATPPPKGA 1263 Query: 292 AATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRG-PASMGGSMNPAS 350 AT + L +K A N + P P+G PA+ P Sbjct: 1264 PTPPAATPPSLKGGLATPPHKG-----------APNPAVVTPPSPKGGPATSPPKGAPTP 1312 Query: 351 MAAGM-TPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPG 409 AA +P G G P P PP ++P G T P P S G Sbjct: 1313 PAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGT----PTLPATTPSS----------KG 1358 Query: 410 EPNYGNQQYGPN--SQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQPSSGQYPPPTVNMG 467 P + + GP + P+ G PA PP P P P + P+S P Sbjct: 1359 GPTTPSSKEGPTPPAATPSHKGG-PAMTPPSPKRGPAIPSPK--GDPTSPAVIP------ 1409 Query: 468 QYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPP-RPVPVANYPHSPVP-GNPTPPMTPGSS 525 P++ T G++ S+G++ P PV + P + P G P P + G Sbjct: 1410 --LSPKKAPATPVTREGAATP--SKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDP 1465 Query: 526 IPPYLSPSQDVKPPFPPDIKPNMSALPPP 554 P ++P +PP P + + S P Sbjct: 1466 TLPAVTPPSPKEPPAPKQVATSSSPKKAP 1494 Score = 56.2 bits (134), Expect = 2e-07 Identities = 104/445 (23%), Positives = 148/445 (33%), Gaps = 101/445 (22%) Query: 119 PPGKLPMQPPLSSMSSMKPTLSHSDGSF-PYDSVPWQQNTNQPPGSLSVVTTVWGVTNTS 177 PP K P + + ++ +S + SF P +S+ +Q + + P T T S Sbjct: 808 PPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSP-------ATTHSPTPPS 860 Query: 178 QSQVLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQS 237 G P +A P++P G + T + +N P K GPA P +Q+ Sbjct: 861 PK---GAPTPSAVTPLSPKGVTLPPKETPTPSVVNLP---------FPKEGPATPAPKQA 908 Query: 238 MYGRPNYPGSGGFGASYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATATA 297 P +S PA GIP P T PAA + A + Sbjct: 909 -------PALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKW 961 Query: 298 TATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMGGSMNPASMAAGMTP 357 T A P P + GP P+ G PA A +P Sbjct: 962 APTPPAAT-------------PPSP----------KGGPATPSPKGAPTPPA--ATPPSP 996 Query: 358 SGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQ 417 G P P PP ++P P P+ P P+P + Sbjct: 997 KGGPATPSPKGAPTPPAVTP---------------PSPKGSPAAT---PFPKGAST---- 1034 Query: 418 YGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQPSSGQYPPPTVNMGQYYKPEQFNG 477 P + P P PA P P +P P +PS P G P T ++ P Sbjct: 1035 --PPAATPPSPKGSPAATP-LPKGAPTTPAATLPS-PKGG---PATPSLKGAPTPP---- 1083 Query: 478 QNNTFSGSSYSNYSQGNVNRPPR--PVPVANYPHSPVPGNPTP-----PMTPGSSIPPYL 530 ++ + G P+ P+P A P SP G TP P TP ++ P Sbjct: 1084 ------AATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPP--- 1134 Query: 531 SPSQDVKPPFPPDIKPNMSALPPPP 555 SP + P P +A PP P Sbjct: 1135 SPKGGLATPPPKGAPTTPAATPPSP 1159 Score = 56.2 bits (134), Expect = 2e-07 Identities = 103/459 (22%), Positives = 148/459 (32%), Gaps = 62/459 (13%) Query: 113 KSRQSDPPGKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWG 172 K + PP K PP ++ S+K L+ P+ P P T+ Sbjct: 1252 KGGPATPPPKGAPTPPAATPPSLKGGLATP----PHKGAPNPAVVTPPSPKGGPATSPPK 1307 Query: 173 VTNTSQSQVLGNPMANANNPMNPGGNPMASGMTTSNPG------LNSPQFAGQQQQFSAK 226 T + +P + P P G P +T +P +P G S+K Sbjct: 1308 GAPTPPAATPPSPKGSPGTPP-PKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSK 1366 Query: 227 AGPAQPYIQQSMYGRPNY-PGSGGFGASYP---GGPNAPAGMGIPPHTRPPADFTQPAAA 282 GP P S G P P S G + P G P +PA + + P P T+ AA Sbjct: 1367 EGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAA 1426 Query: 283 AAAAAVAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQF--MNQPGPRGPA 340 + A T +L++ + GP P+ + + P P+ P Sbjct: 1427 TPSKGDLTPPAV-------TPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPP 1479 Query: 341 SMGGSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLPI 400 + P +A +P P M P P + P P+ +P Sbjct: 1480 A------PKQVATSSSPKKAPATPAPMGAPTLPAVIPSS---------------PKEVPA 1518 Query: 401 QNIKRPYPGEPNYGN-QQYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQR-MPSQPSSGQ 458 R P P + P + P + PA P P +P P + P+ PSS + Sbjct: 1519 TPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKE 1578 Query: 459 YP-PPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPP---RPVPVANYPHSPVPG 514 PP V P + G + S V P P P A P SP G Sbjct: 1579 ASSPPAVT------PSTYKG-----APSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKG 1627 Query: 515 NPTPPMTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPP 553 TP + PP S P P + M A P Sbjct: 1628 PATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVP 1666 Score = 53.5 bits (127), Expect = 1e-06 Identities = 95/454 (20%), Positives = 148/454 (32%), Gaps = 70/454 (15%) Query: 128 PLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWGVTNTSQSQVLGNPMA 187 PL S + PT++ +FP +S P ++ T TS +P Sbjct: 634 PLLKSSLITPTVA----AFPLESAD--------PAGVAPTTA----KGTSTYTTTASPFL 677 Query: 188 NANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQSMYGRPNYPGS 247 + P +P+ G T+ P + + +++ P P Q + + Sbjct: 678 EGTVSLAPKNHPVKEGTLTTLPLVPT----------ASENCPVAPSPQNTCAPLATLVLA 727 Query: 248 GGFGASYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATATATATATVAALQ 307 S P PAG PP T+ + +A A A+ T + A+AT A+ + Sbjct: 728 PEIPKSVPSPSLPPAGT--PPGTKKVDGISHTSALAPVASSPKECPTEDSGASAT-ASSK 784 Query: 308 ETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPAS----MGGSMNPAS-MAAGMTPSGMSG 362 T + P+G + + Q P +G A +G +P S + A P Sbjct: 785 GTLTYLADSPSPLGVS--VSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLS 842 Query: 363 ---------------PPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLPI--QNIKR 405 PP P P ++P G +P + P P +LP + Sbjct: 843 FQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPAT 902 Query: 406 PYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQPSSGQYPPPTVN 465 P P + + + P P P P +P P PS P P Sbjct: 903 PAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPK-- 960 Query: 466 MGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHSPVPGNPTPPMTPGSS 525 + P + G + +G P P A P SP G P P G+ Sbjct: 961 ----WAPTPPAATPPSPKGGPATPSPKG------APTPPAATPPSP-KGGPATPSPKGAP 1009 Query: 526 IPPYLSP----SQDVKPPFPPDIKPNMSALPPPP 555 PP ++P PFP +A PP P Sbjct: 1010 TPPAVTPPSPKGSPAATPFPKGASTPPAATPPSP 1043 Score = 40.4 bits (93), Expect = 0.009 Identities = 38/150 (25%), Positives = 49/150 (32%), Gaps = 21/150 (14%) Query: 866 GPGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPP 925 G P PP P G+ + +G P G P S+ P + P Sbjct: 1031 GASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG---APTPPAATP 1087 Query: 926 DMPNNMAALEKPLSHPMQE------------TMPHAGSSDQPH---PSIQQGLHVPHPSS 970 P A P PM T PH G+ P PS + GL P P Sbjct: 1088 PSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPK- 1146 Query: 971 QSGPPLHHSGAPPPPPSQPPRQPPQAAPSS 1000 G P + PP P PP+ AP++ Sbjct: 1147 --GAPTTPAATPPSPKGGLATPPPKGAPTT 1174 Score = 37.4 bits (85), Expect = 0.076 Identities = 59/247 (23%), Positives = 76/247 (30%), Gaps = 50/247 (20%) Query: 818 PTCSWRPVPIKSDLHIKDDPDGIPSKRFKTMSPSQMIMPNVMEMIAALGPGPSPYPLPPP 877 P+ W P P + P G P+ T SP P AA P P P P Sbjct: 957 PSPKWAPTPPAAT---PPSPKGGPA----TPSPKGAPTPP-----AATPPSPKGGPATPS 1004 Query: 878 PGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKP 937 P G + + + P G+P T PP + PP + AA P Sbjct: 1005 PKGAPTPPAVTPPS----------PKGSPAATPFPKGASTPPAAT-PPSPKGSPAATPLP 1053 Query: 938 LSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAA 997 P T P A PS + G P S G P + PP P P P+ A Sbjct: 1054 KGAP---TTPAATL-----PSPKGG---PATPSLKGAPTPPAATPPSPKGGPATPSPKGA 1102 Query: 998 P--------------SSHPHSDLTFNPSSALEGQAGAQGASDMPEPSLDLLPELTNPDEL 1043 P ++ PH P++ G G + P P T P Sbjct: 1103 PMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG--GLATPPPKGAPTTPAATPPSPK 1160 Query: 1044 LSYLDPP 1050 PP Sbjct: 1161 GGLATPP 1167 Score = 37.4 bits (85), Expect = 0.076 Identities = 41/168 (24%), Positives = 54/168 (32%), Gaps = 24/168 (14%) Query: 863 AALGPGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLS 922 AA P P PPP G + ++ P GG + P + Sbjct: 1153 AATPPSPKGGLATPPPKGAPTTPAAT-------------PPSPKGGLATPSPKGAPTTPA 1199 Query: 923 HPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSGAP 982 P P A P P T P A PS + GL P P G P + P Sbjct: 1200 ATPPSPKGGLATPSPKGAP---TTPAATP-----PSPKGGLATPSPK---GAPTTPAATP 1248 Query: 983 PPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEGQAGAQGASDMPEPS 1030 P P P PP+ AP+ + + A GA + + PS Sbjct: 1249 PSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPS 1296 Score = 35.8 bits (81), Expect = 0.22 Identities = 119/561 (21%), Positives = 170/561 (30%), Gaps = 137/561 (24%) Query: 117 SDPPGKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTN--QPPGSLSVVTTV---- 170 + PP P P ++ P+ S G+ P P P G+ ++ T Sbjct: 1303 TSPPKGAPTPP-----AATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK 1357 Query: 171 WGVTNTSQSQVLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQ---FSAKA 227 G T S + P A P + GG M P + SP+ S K Sbjct: 1358 GGPTTPSSKE---GPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKK 1414 Query: 228 GPAQPYIQQSMYGRPNYPGSGGF--------------GASYP-GGPNAPAGMGIP--PHT 270 PA P ++ P G S P GGP P+ G P P Sbjct: 1415 APATPVTREGAAT----PSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAV 1470 Query: 271 RPPADFTQPAA--AAAAAAVAAAAATATATATATVAALQETQNKDI-----NQYGPMGPT 323 PP+ PA A +++ A AT T+ A+ + K++ ++ P+ PT Sbjct: 1471 TPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPT 1530 Query: 324 QAYNSQ---------------FMNQPGPRGP--------ASMGGSMNPASMAAGMTPSGM 360 S+ M P P+ A S AS +TPS Sbjct: 1531 ATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTY 1590 Query: 361 SGPPMGMNQPRPPGI-SPFGTHGQRMPQQTYPGPR-----------PQSLPIQ-NIKRPY 407 G P PP + SP P T P P P S P+ + + Sbjct: 1591 KGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDS 1650 Query: 408 PGEPNYGNQQYG----------PNSQFPTQPGQY---PAPNPPRPLTSPNYPGQRMPSQP 454 P P + G P + PT + PAP +T+P G + ++ Sbjct: 1651 PTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQ--TKK 1708 Query: 455 SSGQYPP----PTVNMGQY----------YKPEQFNGQNNTFSGSSYSNYSQGNVNRPPR 500 SS PP P+ G P Q + T G S+ +G + P Sbjct: 1709 SSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQ-KDSSKTAKGKDASHSPKGPLAPPES 1767 Query: 501 --------------------------PVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQ 534 P P + P +P P PP P L Sbjct: 1768 KASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLES 1827 Query: 535 DVKPPFPPDIKPNMSALPPPP 555 KP P D + +PP P Sbjct: 1828 PSKPLAPADEDELLPLIPPEP 1848 Score = 35.4 bits (80), Expect = 0.29 Identities = 36/144 (25%), Positives = 51/144 (35%), Gaps = 16/144 (11%) Query: 918 PPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLH 977 PP ++ P P A+ P P + A S PS +G P P PP Sbjct: 1550 PPAMTVPS--PKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKG--APSPKELLIPPAV 1605 Query: 978 HSGAP----------PPPPSQPPRQP-PQAAPSSHPHSDLTFNPSSALEGQAGAQGASDM 1026 S +P PP P + P P P+ P+S P + + S + + + Sbjct: 1606 TSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATV 1665 Query: 1027 PEPSLDLLPELTNPDELLSYLDPP 1050 P+ S LP P L L P Sbjct: 1666 PQASKG-LPAKKGPTALKEVLVAP 1688 Score = 34.3 bits (77), Expect = 0.64 Identities = 29/91 (31%), Positives = 38/91 (41%), Gaps = 17/91 (18%) Query: 917 GPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPL 976 G P P P AA L + T PH G+ P+P++ V PS + GP Sbjct: 1253 GGPATPPPKGAPTPPAATPPSLKGGLA-TPPHKGA---PNPAV-----VTPPSPKGGPAT 1303 Query: 977 HH-SGAPPPPPSQPPRQ-------PPQAAPS 999 GAP PP + PP PP+ AP+ Sbjct: 1304 SPPKGAPTPPAATPPSPKGSPGTPPPKGAPT 1334 Score = 32.3 bits (72), Expect = 2.4 Identities = 46/184 (25%), Positives = 61/184 (33%), Gaps = 19/184 (10%) Query: 866 GPGPSPYP-LPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMND-FMHGPPQLSH 923 GP SP P PP T + S G P G P ++ G P L Sbjct: 1300 GPATSPPKGAPTPPAATPPSPKGSPGTPP--------PKGAPTPPAVTPPSPKGTPTL-- 1349 Query: 924 PPDMPNNMAALEKPLSH----PMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHS 979 P P++ P S P T H G PS ++G +P P P Sbjct: 1350 PATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIP 1409 Query: 980 GAPPPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEGQA--GAQGASDMPEPSLD-LLPE 1036 +P P+ P + A PS + P S + A +G P D LP Sbjct: 1410 LSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPA 1469 Query: 1037 LTNP 1040 +T P Sbjct: 1470 VTPP 1473 Score = 31.6 bits (70), Expect = 4.2 Identities = 25/89 (28%), Positives = 35/89 (39%), Gaps = 4/89 (4%) Query: 481 TFSGSSYSNYSQGNVNRPPRPVPVANYPHSPV--PGNPTPPMTPGSSIPPYLSPSQDVKP 538 T GS+ + GN++ P PV + P + + G+ P T S PP SP P Sbjct: 810 TKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPP--SPKGAPTP 867 Query: 539 PFPPDIKPNMSALPPPPANHNDELRLTFP 567 + P LPP + L FP Sbjct: 868 SAVTPLSPKGVTLPPKETPTPSVVNLPFP 896 Score = 31.2 bits (69), Expect = 5.5 Identities = 48/198 (24%), Positives = 62/198 (31%), Gaps = 28/198 (14%) Query: 863 AALGP-GPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQL 921 +AL P SP P G ++ S Y D P +P G S++ PP Sbjct: 758 SALAPVASSPKECPTEDSGASATASSKGTLTYLA----DSP--SPLGVSVSPQTKRPPTK 811 Query: 922 --SHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSG------ 973 S PD P + L P+S +P S Q H P P S G Sbjct: 812 KGSAGPDTP--IGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSA 869 Query: 974 -PPLHHSGAPPPPPSQP---------PRQ-PPQAAPSSHPHSDLTFNPSSALEGQAGAQG 1022 PL G PP P P++ P AP P +T + +G Sbjct: 870 VTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKG 929 Query: 1023 ASDMPEPSLDLLPELTNP 1040 P P P P Sbjct: 930 IPASPSPKGAPTPPAATP 947 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 69.3 bits (168), Expect = 2e-11 Identities = 118/473 (24%), Positives = 157/473 (33%), Gaps = 66/473 (13%) Query: 113 KSRQSDP---PGKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTT 169 KSR +D KLP + P S S+K + S +D + + ++ PG LS V Sbjct: 112 KSRTTDTFRSEQKLPGRSP--STISLKESKSRTD-------LKEEHKSSMMPGFLSEVNA 162 Query: 170 VWGVTNTSQSQVLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGP 229 + V++ + N NP + + S S Q Q++Q + Sbjct: 163 LSAVSS----------VVNKFNPFD-----LISDSEASQEETTKKQKVVQKEQGKPEGII 207 Query: 230 AQPYIQQSMYGRPNYPGSGGFGASYPGGPNA------------PAGMGIP---PHTRPPA 274 P QQ P G G G P + P G G P P P Sbjct: 208 KPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQT 267 Query: 275 DFTQPAAAAAAAAVAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQP 334 D + A+ A + +L I Q P P +QP Sbjct: 268 DHAKLPLQRDASRPQTKQADIVR-GESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP 326 Query: 335 GP-RGPASMGGSMNPASMAAG-----MTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQ 388 GP + PA G P + G + P G + PP QP P P G P Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA---QPLGPAKPPAQQTGSEKPSS 383 Query: 389 TYPGPRPQSLPIQNIKRP--YPGEPNYGNQQYGPNSQFPTQPG-QYPAPNPPRPLTSPNY 445 PGP+ + P K P PG QQ G QPG Q PA P T Sbjct: 384 EQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQ 443 Query: 446 PGQ-RMPSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPV 504 PG ++P+Q +G G P Q G + Q +PP P Sbjct: 444 PGPGKIPAQ-QAGPGKTSAQQTGPTKPPSQL-------PGPAKPPPQQPGPAKPPPQQPG 495 Query: 505 ANYPHSPVPGN-PTPPMTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPPPPA 556 + P S PG+ PP PG + P P KPP SA P PA Sbjct: 496 SAKPPSQQPGSTKPPPQQPGPAKPSPQQPG-STKPPSQQPGSAKPSAQQPSPA 547 Score = 64.7 bits (156), Expect = 4e-10 Identities = 102/440 (23%), Positives = 139/440 (31%), Gaps = 86/440 (19%) Query: 135 MKPTLSHSDGSFPYDSVPWQQNTNQPP----GSLSVVTTVWGVTNTSQSQVLGNPMANAN 190 +KP L P +P QQ + P G+ +++ SQ G P+ Sbjct: 207 IKPPLQQQ----PPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPT 262 Query: 191 NPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQSMYGRPNYPGSGGF 250 + S P + + P++P IQQ G+P Sbjct: 263 QTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPP------- 315 Query: 251 GASYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATATATATATVAALQETQ 310 A PG + G PP P+ T+P A T A Sbjct: 316 -AQQPGHEKSQPGPAKPP--AQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQ-------- 364 Query: 311 NKDINQYGPMGPTQAYNSQFMNQPGPRGPASMGGSMNPASMAAGMTPSGMSGPP-MGMNQ 369 P+GP + PA GS P+S G P ++ PP +G Sbjct: 365 --------PLGPAKP-------------PAQQTGSEKPSSEQPG--PKALAQPPGVGKTP 401 Query: 370 PRPPGIS--PFGTHGQRMPQQTYPG-------PRPQSLPIQNIKRPYPGEPNYGNQQYGP 420 + PG + P G P PG P P P+Q PG QQ GP Sbjct: 402 AQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQ-----PGPGKIPAQQAGP 456 Query: 421 NSQFPTQ------PGQYPAPNPPRPLTSPNYPGQRMPSQPSSGQYPPPTVNMGQYYKPEQ 474 Q P Q P P P P PG P G PP+ G P Q Sbjct: 457 GKTSAQQTGPTKPPSQLPGPAKP----PPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQ 512 Query: 475 FNGQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQ 534 G + + Q +PP P + P + P +P P S+ P +S + Sbjct: 513 -------QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQP-SPAKPSAQQSTKP--VSQTG 562 Query: 535 DVKPPFPPDIKPNMSALPPP 554 KP PP + P SA PP Sbjct: 563 SGKPLQPPTVSP--SAKQPP 580 Score = 60.1 bits (144), Expect = 1e-08 Identities = 117/508 (23%), Positives = 163/508 (32%), Gaps = 110/508 (21%) Query: 113 KSRQSDPPGKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWG 172 KS S P K+ QPP + PT + + +P Q++ ++P Sbjct: 237 KSISSQQPEKIKSQPPGTGKPIQGPTQTPQTD---HAKLPLQRDASRP------------ 281 Query: 173 VTNTSQSQVLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQP 232 T Q+ ++ + P +P + PG Q G ++ ++ GPA+P Sbjct: 282 --QTKQADIVRGESVKPSLP-----SPSKPPIQQPTPGKPPAQQPGHEK---SQPGPAKP 331 Query: 233 YIQQSMYGRPNYPGSGGFGASYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAA 292 Q S +P A PG P P T+PPA QP A A + Sbjct: 332 PAQPSGLTKPL--------AQQPGTVKPPVQP--PGTTKPPA---QPLGPAKPPAQQTGS 378 Query: 293 ATATATATATVAALQE--TQNKDINQYGPMGP-TQAYNSQ--FMNQPGPRGPASMGG-SM 346 ++ A Q Q GP P TQ + QPG + PA G + Sbjct: 379 EKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTK 438 Query: 347 NPASMAA-GMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGP-RPQSLPIQNIK 404 P G P+ +GP Q P P G P PGP +P + K Sbjct: 439 TPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAK 498 Query: 405 RP--YPGEPNYGNQQYGPNSQFPTQPGQYPAPN-------PPRPLTSPNYPGQRMPSQP- 454 P PG QQ GP P QPG P+ P SP P + ++P Sbjct: 499 PPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPV 558 Query: 455 ----SSGQYPPPTVNMGQYYKPEQF--------------------NGQNNTFSGSSYSNY 490 S PPTV+ P Q NT + + Sbjct: 559 SQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVC 618 Query: 491 SQGNVNRPPRPVPVANY------------------PHSPVPGNPTPPMTPGSSI------ 526 S N P V + P SP P T P+T S++ Sbjct: 619 SLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQ 678 Query: 527 PPYLSPSQDVKPPFPPDIKPNMSALPPP 554 P SP +D P K ++S P P Sbjct: 679 PQQTSPKKDAAP------KQDLSKAPEP 700 Score = 40.8 bits (94), Expect = 0.007 Identities = 41/152 (26%), Positives = 50/152 (32%), Gaps = 9/152 (5%) Query: 864 ALGPGPSPYPLPPP-PGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLS 922 A PGP+ P+ P PG + + Q G P PG PPQ Sbjct: 431 AKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKP------PPQQP 484 Query: 923 HPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSG--PPLHHSG 980 P P KP S T P PS QQ PS Q G P Sbjct: 485 GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQP 544 Query: 981 APPPPPSQPPRQPPQAAPSSHPHSDLTFNPSS 1012 +P P +Q +P S P T +PS+ Sbjct: 545 SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSA 576 Score = 38.5 bits (88), Expect = 0.034 Identities = 43/149 (28%), Positives = 52/149 (34%), Gaps = 16/149 (10%) Query: 918 PPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHP-SIQQGLHVPH-PSSQSGP- 974 PP + PP P P P Q+T SS+QP P ++ Q V P+ Q GP Sbjct: 355 PPGTTKPPAQPLG------PAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPA 408 Query: 975 --PLHHSGAPPPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEGQAG-----AQGASDMP 1027 P G P P QP Q P AP P QAG AQ Sbjct: 409 KPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTK 468 Query: 1028 EPSLDLLPELTNPDELLSYLDPPDLPSNS 1056 PS P P + PP P ++ Sbjct: 469 PPSQLPGPAKPPPQQPGPAKPPPQQPGSA 497 Score = 35.4 bits (80), Expect = 0.29 Identities = 70/317 (22%), Positives = 104/317 (32%), Gaps = 46/317 (14%) Query: 282 AAAAAAVAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGP-- 339 AAAAAA A+ + + TA A ++ D++Q Q Q P+G Sbjct: 17 AAAAAAGGGASGAGSPSHTAIPAGMEA----DLSQLSEEERRQIAAVMSRAQGLPKGSVP 72 Query: 340 --ASMGGSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQS 397 A+ SM+ P SG P +P PG+S T +Q PG P + Sbjct: 73 PAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPST 132 Query: 398 LPIQNIK-RPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNP--PRPLTSPNYPGQRMPS-- 452 + ++ K R E + + G S+ N P L S + Q + Sbjct: 133 ISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKK 192 Query: 453 ---------------QPSSGQYPPPTV--NMGQYYKPEQFNGQNNTFSGSSYSNYSQ--- 492 +P Q PP + G P Q +G + S Sbjct: 193 QKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPP 252 Query: 493 --GNVNRPPRPVPVANYPHSPVPGNPTPPMTP------GSSIPPYL-----SPSQDVKPP 539 G + P P ++ P+ + + P T G S+ P L P Q P Sbjct: 253 GTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPG 312 Query: 540 FPPDIKPNMSALPPPPA 556 PP +P P PA Sbjct: 313 KPPAQQPGHEKSQPGPA 329 Score = 35.4 bits (80), Expect = 0.29 Identities = 82/409 (20%), Positives = 127/409 (31%), Gaps = 61/409 (14%) Query: 171 WGVTNTSQSQVLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQ--------FAGQQQQ 222 W N + LG +A + P A TTS +SPQ A +Q Sbjct: 635 WLCLNCQMKRALGGDLAPVPSSPQPKLKT-APVTTTSAVSKSSPQPQQTSPKKDAAPKQD 693 Query: 223 FSAKAGPAQP---YIQQSMYGRPNYPGSGGFGASYPGGPNAPAGMGIPPHT-RPPADFTQ 278 S P +P Q +++G P+ A P P +P + P + Sbjct: 694 LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDK 753 Query: 279 PAAAAAAAAVAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPR- 337 P ++++AT + + + + P+ A SQ G + Sbjct: 754 PKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKV 813 Query: 338 GPASMGGSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQS 397 P PAS + ++ G S G Q + P + QT P+P + Sbjct: 814 SPFDSKAIPRPASDSKIISHPGPSSESKGQKQ-----VDPVQKKEEPKKAQTKMSPKPDA 868 Query: 398 LPIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQPSSG 457 P+ P P P PRP P + +P Sbjct: 869 KPM---------------------------PKGSPTPPGPRPTAGQTVPTPQQSPKPQE- 900 Query: 458 QYPPPTVNMGQY---------YKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVA-NY 507 Q ++N+G E G+ F S +S S ++ +P P + + Sbjct: 901 QSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQAS-NLISTAGQPGPHSQSG 959 Query: 508 PHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPPPPA 556 P +P+ P P P S PP S PP P P P A Sbjct: 960 PGAPMKQAPAPSQPPTSQGPP---KSTGQAPPAPAKSIPVKKETKAPAA 1005 Score = 34.3 bits (77), Expect = 0.64 Identities = 40/176 (22%), Positives = 56/176 (31%), Gaps = 21/176 (11%) Query: 867 PGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPPD 926 P P P PP + +Q Q P PG T P Q P Sbjct: 401 PAQQPGPAKPPTQQVGTPKPLAQQPGLQS------PAKAPGPTKT------PVQQPGPGK 448 Query: 927 MPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSGAPPPPP 986 +P A P Q+T P S P P+ P + PP G+ PP Sbjct: 449 IPAQQAG---PGKTSAQQTGPTKPPSQLPGPAKPP----PQQPGPAKPPPQQPGSAKPPS 501 Query: 987 SQP--PRQPPQAAPSSHPHSDLTFNPSSALEGQAGAQGASDMPEPSLDLLPELTNP 1040 QP + PPQ + P + + A+ ++ P P+ + T P Sbjct: 502 QQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557 Score = 33.5 bits (75), Expect = 1.1 Identities = 46/198 (23%), Positives = 65/198 (32%), Gaps = 14/198 (7%) Query: 255 PGGPNAPAGMGIPPHTRPPADFTQPAAAAA------AAAVAAAAATATATATATVAALQE 308 P P G PP RP A T P + + + + T + QE Sbjct: 866 PDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQE 925 Query: 309 TQNKDINQYGPMGPTQAYN-SQFMNQPGPRGPASMGGSMNPASMAAGMTPSGMSGPPMGM 367 T + +G +QA N QPGP + G M A A P GPP Sbjct: 926 TVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQA--PAPSQPPTSQGPPKST 983 Query: 368 NQ-PRPPGISPFGTHGQRMPQQTYPGPRPQSLP----IQNIKRPYPGEPNYGNQQYGPNS 422 Q P P S + P P+ + P + K+P P + + + Sbjct: 984 GQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKA 1043 Query: 423 QFPTQPGQYPAPNPPRPL 440 PT+ + P P PL Sbjct: 1044 VLPTKLEKSPKPESTCPL 1061 Score = 32.7 bits (73), Expect = 1.9 Identities = 31/125 (24%), Positives = 40/125 (32%), Gaps = 26/125 (20%) Query: 902 PHGNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQP------ 955 P G + GP L+ PP + A P P Q+ + QP Sbjct: 372 PAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPA 431 Query: 956 ------HPSIQQGLHVPHPSSQSG-------------PPLHHSGAPPPPPSQP-PRQPPQ 995 +QQ P+ Q+G PP G PPP QP P +PP Sbjct: 432 KAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP 491 Query: 996 AAPSS 1000 P S Sbjct: 492 QQPGS 496 Score = 32.7 bits (73), Expect = 1.9 Identities = 20/75 (26%), Positives = 25/75 (33%), Gaps = 2/75 (2%) Query: 498 PPRPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPPPPAN 557 P +P P + P PP P PP P PP PP P + LP Sbjct: 2387 PAKPRPFFRSSSLDISAQPPPPPPPPPPPPP--PPPPPPPPPLPPPTSPKPTILPKKKLT 2444 Query: 558 HNDELRLTFPVRDGV 572 + P+ D V Sbjct: 2445 VASPVTTATPLFDAV 2459 Score = 32.0 bits (71), Expect = 3.2 Identities = 17/38 (44%), Positives = 22/38 (57%), Gaps = 4/38 (10%) Query: 966 PHPSSQSGP--PLHHSGAPPPPPSQ--PPRQPPQAAPS 999 P P SQSGP P+ + AP PP+ PP+ QA P+ Sbjct: 952 PGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPA 989 Score = 32.0 bits (71), Expect = 3.2 Identities = 23/83 (27%), Positives = 31/83 (37%), Gaps = 6/83 (7%) Query: 469 YYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRP------VPVANYPHSPVPGNPTPPMTP 522 Y+ + GQ S + S ++ PRP + ++ P P P P PP P Sbjct: 2360 YFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPP 2419 Query: 523 GSSIPPYLSPSQDVKPPFPPDIK 545 PP L P KP P K Sbjct: 2420 PPPPPPPLPPPTSPKPTILPKKK 2442 Score = 32.0 bits (71), Expect = 3.2 Identities = 13/29 (44%), Positives = 14/29 (48%) Query: 974 PPLHHSGAPPPPPSQPPRQPPQAAPSSHP 1002 PP PPPPP PP PP P + P Sbjct: 2405 PPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433 Score = 31.6 bits (70), Expect = 4.2 Identities = 46/201 (22%), Positives = 64/201 (31%), Gaps = 26/201 (12%) Query: 866 GPGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQ--LSH 923 GPG P P +S + G G P P T D P Q S Sbjct: 224 GPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGK---PIQGPTQTPQTDHAKLPLQRDASR 280 Query: 924 PPDMPNNMA-------ALEKPLSHPMQETMPHAGSSDQP-HPSIQQGLHVP--HPSSQSG 973 P ++ +L P P+Q+ P + QP H Q G P PS + Sbjct: 281 PQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTK 340 Query: 974 PPLHHSGAPPP---------PPSQP--PRQPPQAAPSSHPHSDLTFNPSSALEGQAGAQG 1022 P G P PP+QP P +PP S S P + + + Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKT 400 Query: 1023 ASDMPEPSLDLLPELTNPDEL 1043 + P P+ ++ P L Sbjct: 401 PAQQPGPAKPPTQQVGTPKPL 421 Score = 31.6 bits (70), Expect = 4.2 Identities = 16/36 (44%), Positives = 17/36 (47%), Gaps = 5/36 (13%) Query: 969 SSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSHPHS 1004 S+Q PP PPPPP PP PP P P S Sbjct: 2402 SAQPPPP-----PPPPPPPPPPPPPPPPPPLPPPTS 2432 Score = 31.6 bits (70), Expect = 4.2 Identities = 15/45 (33%), Positives = 21/45 (46%) Query: 497 RPPRPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPPFP 541 +PP P P P P P P PP+ P +S P + P + + P Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASP 2448 Score = 31.2 bits (69), Expect = 5.5 Identities = 16/46 (34%), Positives = 19/46 (41%) Query: 957 PSIQQGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSHP 1002 PS+ P P +S + PPPPP PP PP P P Sbjct: 2381 PSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPP 2426 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 69.3 bits (168), Expect = 2e-11 Identities = 118/473 (24%), Positives = 157/473 (33%), Gaps = 66/473 (13%) Query: 113 KSRQSDP---PGKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTT 169 KSR +D KLP + P S S+K + S +D + + ++ PG LS V Sbjct: 112 KSRTTDTFRSEQKLPGRSP--STISLKESKSRTD-------LKEEHKSSMMPGFLSEVNA 162 Query: 170 VWGVTNTSQSQVLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGP 229 + V++ + N NP + + S S Q Q++Q + Sbjct: 163 LSAVSS----------VVNKFNPFD-----LISDSEASQEETTKKQKVVQKEQGKPEGII 207 Query: 230 AQPYIQQSMYGRPNYPGSGGFGASYPGGPNA------------PAGMGIP---PHTRPPA 274 P QQ P G G G P + P G G P P P Sbjct: 208 KPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQT 267 Query: 275 DFTQPAAAAAAAAVAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQP 334 D + A+ A + +L I Q P P +QP Sbjct: 268 DHAKLPLQRDASRPQTKQADIVR-GESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP 326 Query: 335 GP-RGPASMGGSMNPASMAAG-----MTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQ 388 GP + PA G P + G + P G + PP QP P P G P Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA---QPLGPAKPPAQQTGSEKPSS 383 Query: 389 TYPGPRPQSLPIQNIKRP--YPGEPNYGNQQYGPNSQFPTQPG-QYPAPNPPRPLTSPNY 445 PGP+ + P K P PG QQ G QPG Q PA P T Sbjct: 384 EQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQ 443 Query: 446 PGQ-RMPSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPV 504 PG ++P+Q +G G P Q G + Q +PP P Sbjct: 444 PGPGKIPAQ-QAGPGKTSAQQTGPTKPPSQL-------PGPAKPPPQQPGPAKPPPQQPG 495 Query: 505 ANYPHSPVPGN-PTPPMTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPPPPA 556 + P S PG+ PP PG + P P KPP SA P PA Sbjct: 496 SAKPPSQQPGSTKPPPQQPGPAKPSPQQPG-STKPPSQQPGSAKPSAQQPSPA 547 Score = 64.7 bits (156), Expect = 4e-10 Identities = 102/440 (23%), Positives = 139/440 (31%), Gaps = 86/440 (19%) Query: 135 MKPTLSHSDGSFPYDSVPWQQNTNQPP----GSLSVVTTVWGVTNTSQSQVLGNPMANAN 190 +KP L P +P QQ + P G+ +++ SQ G P+ Sbjct: 207 IKPPLQQQ----PPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPT 262 Query: 191 NPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQSMYGRPNYPGSGGF 250 + S P + + P++P IQQ G+P Sbjct: 263 QTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPP------- 315 Query: 251 GASYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATATATATATVAALQETQ 310 A PG + G PP P+ T+P A T A Sbjct: 316 -AQQPGHEKSQPGPAKPP--AQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQ-------- 364 Query: 311 NKDINQYGPMGPTQAYNSQFMNQPGPRGPASMGGSMNPASMAAGMTPSGMSGPP-MGMNQ 369 P+GP + PA GS P+S G P ++ PP +G Sbjct: 365 --------PLGPAKP-------------PAQQTGSEKPSSEQPG--PKALAQPPGVGKTP 401 Query: 370 PRPPGIS--PFGTHGQRMPQQTYPG-------PRPQSLPIQNIKRPYPGEPNYGNQQYGP 420 + PG + P G P PG P P P+Q PG QQ GP Sbjct: 402 AQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQ-----PGPGKIPAQQAGP 456 Query: 421 NSQFPTQ------PGQYPAPNPPRPLTSPNYPGQRMPSQPSSGQYPPPTVNMGQYYKPEQ 474 Q P Q P P P P PG P G PP+ G P Q Sbjct: 457 GKTSAQQTGPTKPPSQLPGPAKP----PPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQ 512 Query: 475 FNGQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQ 534 G + + Q +PP P + P + P +P P S+ P +S + Sbjct: 513 -------QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQP-SPAKPSAQQSTKP--VSQTG 562 Query: 535 DVKPPFPPDIKPNMSALPPP 554 KP PP + P SA PP Sbjct: 563 SGKPLQPPTVSP--SAKQPP 580 Score = 60.1 bits (144), Expect = 1e-08 Identities = 117/508 (23%), Positives = 163/508 (32%), Gaps = 110/508 (21%) Query: 113 KSRQSDPPGKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWG 172 KS S P K+ QPP + PT + + +P Q++ ++P Sbjct: 237 KSISSQQPEKIKSQPPGTGKPIQGPTQTPQTD---HAKLPLQRDASRP------------ 281 Query: 173 VTNTSQSQVLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQP 232 T Q+ ++ + P +P + PG Q G ++ ++ GPA+P Sbjct: 282 --QTKQADIVRGESVKPSLP-----SPSKPPIQQPTPGKPPAQQPGHEK---SQPGPAKP 331 Query: 233 YIQQSMYGRPNYPGSGGFGASYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAA 292 Q S +P A PG P P T+PPA QP A A + Sbjct: 332 PAQPSGLTKPL--------AQQPGTVKPPVQP--PGTTKPPA---QPLGPAKPPAQQTGS 378 Query: 293 ATATATATATVAALQE--TQNKDINQYGPMGP-TQAYNSQ--FMNQPGPRGPASMGG-SM 346 ++ A Q Q GP P TQ + QPG + PA G + Sbjct: 379 EKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTK 438 Query: 347 NPASMAA-GMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGP-RPQSLPIQNIK 404 P G P+ +GP Q P P G P PGP +P + K Sbjct: 439 TPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAK 498 Query: 405 RP--YPGEPNYGNQQYGPNSQFPTQPGQYPAPN-------PPRPLTSPNYPGQRMPSQP- 454 P PG QQ GP P QPG P+ P SP P + ++P Sbjct: 499 PPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPV 558 Query: 455 ----SSGQYPPPTVNMGQYYKPEQF--------------------NGQNNTFSGSSYSNY 490 S PPTV+ P Q NT + + Sbjct: 559 SQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVC 618 Query: 491 SQGNVNRPPRPVPVANY------------------PHSPVPGNPTPPMTPGSSI------ 526 S N P V + P SP P T P+T S++ Sbjct: 619 SLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQ 678 Query: 527 PPYLSPSQDVKPPFPPDIKPNMSALPPP 554 P SP +D P K ++S P P Sbjct: 679 PQQTSPKKDAAP------KQDLSKAPEP 700 Score = 40.8 bits (94), Expect = 0.007 Identities = 41/152 (26%), Positives = 50/152 (32%), Gaps = 9/152 (5%) Query: 864 ALGPGPSPYPLPPP-PGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLS 922 A PGP+ P+ P PG + + Q G P PG PPQ Sbjct: 431 AKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKP------PPQQP 484 Query: 923 HPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSG--PPLHHSG 980 P P KP S T P PS QQ PS Q G P Sbjct: 485 GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQP 544 Query: 981 APPPPPSQPPRQPPQAAPSSHPHSDLTFNPSS 1012 +P P +Q +P S P T +PS+ Sbjct: 545 SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSA 576 Score = 38.5 bits (88), Expect = 0.034 Identities = 43/149 (28%), Positives = 52/149 (34%), Gaps = 16/149 (10%) Query: 918 PPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHP-SIQQGLHVPH-PSSQSGP- 974 PP + PP P P P Q+T SS+QP P ++ Q V P+ Q GP Sbjct: 355 PPGTTKPPAQPLG------PAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPA 408 Query: 975 --PLHHSGAPPPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEGQAG-----AQGASDMP 1027 P G P P QP Q P AP P QAG AQ Sbjct: 409 KPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTK 468 Query: 1028 EPSLDLLPELTNPDELLSYLDPPDLPSNS 1056 PS P P + PP P ++ Sbjct: 469 PPSQLPGPAKPPPQQPGPAKPPPQQPGSA 497 Score = 35.4 bits (80), Expect = 0.29 Identities = 70/317 (22%), Positives = 104/317 (32%), Gaps = 46/317 (14%) Query: 282 AAAAAAVAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGP-- 339 AAAAAA A+ + + TA A ++ D++Q Q Q P+G Sbjct: 17 AAAAAAGGGASGAGSPSHTAIPAGMEA----DLSQLSEEERRQIAAVMSRAQGLPKGSVP 72 Query: 340 --ASMGGSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQS 397 A+ SM+ P SG P +P PG+S T +Q PG P + Sbjct: 73 PAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPST 132 Query: 398 LPIQNIK-RPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNP--PRPLTSPNYPGQRMPS-- 452 + ++ K R E + + G S+ N P L S + Q + Sbjct: 133 ISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKK 192 Query: 453 ---------------QPSSGQYPPPTV--NMGQYYKPEQFNGQNNTFSGSSYSNYSQ--- 492 +P Q PP + G P Q +G + S Sbjct: 193 QKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPP 252 Query: 493 --GNVNRPPRPVPVANYPHSPVPGNPTPPMTP------GSSIPPYL-----SPSQDVKPP 539 G + P P ++ P+ + + P T G S+ P L P Q P Sbjct: 253 GTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPG 312 Query: 540 FPPDIKPNMSALPPPPA 556 PP +P P PA Sbjct: 313 KPPAQQPGHEKSQPGPA 329 Score = 35.4 bits (80), Expect = 0.29 Identities = 82/409 (20%), Positives = 127/409 (31%), Gaps = 61/409 (14%) Query: 171 WGVTNTSQSQVLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQ--------FAGQQQQ 222 W N + LG +A + P A TTS +SPQ A +Q Sbjct: 635 WLCLNCQMKRALGGDLAPVPSSPQPKLKT-APVTTTSAVSKSSPQPQQTSPKKDAAPKQD 693 Query: 223 FSAKAGPAQP---YIQQSMYGRPNYPGSGGFGASYPGGPNAPAGMGIPPHT-RPPADFTQ 278 S P +P Q +++G P+ A P P +P + P + Sbjct: 694 LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDK 753 Query: 279 PAAAAAAAAVAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPR- 337 P ++++AT + + + + P+ A SQ G + Sbjct: 754 PKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKV 813 Query: 338 GPASMGGSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQS 397 P PAS + ++ G S G Q + P + QT P+P + Sbjct: 814 SPFDSKAIPRPASDSKIISHPGPSSESKGQKQ-----VDPVQKKEEPKKAQTKMSPKPDA 868 Query: 398 LPIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQPSSG 457 P+ P P P PRP P + +P Sbjct: 869 KPM---------------------------PKGSPTPPGPRPTAGQTVPTPQQSPKPQE- 900 Query: 458 QYPPPTVNMGQY---------YKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVA-NY 507 Q ++N+G E G+ F S +S S ++ +P P + + Sbjct: 901 QSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQAS-NLISTAGQPGPHSQSG 959 Query: 508 PHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPPPPA 556 P +P+ P P P S PP S PP P P P A Sbjct: 960 PGAPMKQAPAPSQPPTSQGPP---KSTGQAPPAPAKSIPVKKETKAPAA 1005 Score = 34.3 bits (77), Expect = 0.64 Identities = 40/176 (22%), Positives = 56/176 (31%), Gaps = 21/176 (11%) Query: 867 PGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPPD 926 P P P PP + +Q Q P PG T P Q P Sbjct: 401 PAQQPGPAKPPTQQVGTPKPLAQQPGLQS------PAKAPGPTKT------PVQQPGPGK 448 Query: 927 MPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSGAPPPPP 986 +P A P Q+T P S P P+ P + PP G+ PP Sbjct: 449 IPAQQAG---PGKTSAQQTGPTKPPSQLPGPAKPP----PQQPGPAKPPPQQPGSAKPPS 501 Query: 987 SQP--PRQPPQAAPSSHPHSDLTFNPSSALEGQAGAQGASDMPEPSLDLLPELTNP 1040 QP + PPQ + P + + A+ ++ P P+ + T P Sbjct: 502 QQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557 Score = 33.5 bits (75), Expect = 1.1 Identities = 46/198 (23%), Positives = 65/198 (32%), Gaps = 14/198 (7%) Query: 255 PGGPNAPAGMGIPPHTRPPADFTQPAAAAA------AAAVAAAAATATATATATVAALQE 308 P P G PP RP A T P + + + + T + QE Sbjct: 866 PDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQE 925 Query: 309 TQNKDINQYGPMGPTQAYN-SQFMNQPGPRGPASMGGSMNPASMAAGMTPSGMSGPPMGM 367 T + +G +QA N QPGP + G M A A P GPP Sbjct: 926 TVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQA--PAPSQPPTSQGPPKST 983 Query: 368 NQ-PRPPGISPFGTHGQRMPQQTYPGPRPQSLP----IQNIKRPYPGEPNYGNQQYGPNS 422 Q P P S + P P+ + P + K+P P + + + Sbjct: 984 GQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKA 1043 Query: 423 QFPTQPGQYPAPNPPRPL 440 PT+ + P P PL Sbjct: 1044 VLPTKLEKSPKPESTCPL 1061 Score = 32.7 bits (73), Expect = 1.9 Identities = 31/125 (24%), Positives = 40/125 (32%), Gaps = 26/125 (20%) Query: 902 PHGNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQP------ 955 P G + GP L+ PP + A P P Q+ + QP Sbjct: 372 PAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPA 431 Query: 956 ------HPSIQQGLHVPHPSSQSG-------------PPLHHSGAPPPPPSQP-PRQPPQ 995 +QQ P+ Q+G PP G PPP QP P +PP Sbjct: 432 KAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP 491 Query: 996 AAPSS 1000 P S Sbjct: 492 QQPGS 496 Score = 32.7 bits (73), Expect = 1.9 Identities = 20/75 (26%), Positives = 25/75 (33%), Gaps = 2/75 (2%) Query: 498 PPRPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPPPPAN 557 P +P P + P PP P PP P PP PP P + LP Sbjct: 2387 PAKPRPFFRSSSLDISAQPPPPPPPPPPPPP--PPPPPPPPPLPPPTSPKPTILPKKKLT 2444 Query: 558 HNDELRLTFPVRDGV 572 + P+ D V Sbjct: 2445 VASPVTTATPLFDAV 2459 Score = 32.0 bits (71), Expect = 3.2 Identities = 17/38 (44%), Positives = 22/38 (57%), Gaps = 4/38 (10%) Query: 966 PHPSSQSGP--PLHHSGAPPPPPSQ--PPRQPPQAAPS 999 P P SQSGP P+ + AP PP+ PP+ QA P+ Sbjct: 952 PGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPA 989 Score = 32.0 bits (71), Expect = 3.2 Identities = 23/83 (27%), Positives = 31/83 (37%), Gaps = 6/83 (7%) Query: 469 YYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRP------VPVANYPHSPVPGNPTPPMTP 522 Y+ + GQ S + S ++ PRP + ++ P P P P PP P Sbjct: 2360 YFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPP 2419 Query: 523 GSSIPPYLSPSQDVKPPFPPDIK 545 PP L P KP P K Sbjct: 2420 PPPPPPPLPPPTSPKPTILPKKK 2442 Score = 32.0 bits (71), Expect = 3.2 Identities = 13/29 (44%), Positives = 14/29 (48%) Query: 974 PPLHHSGAPPPPPSQPPRQPPQAAPSSHP 1002 PP PPPPP PP PP P + P Sbjct: 2405 PPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433 Score = 31.6 bits (70), Expect = 4.2 Identities = 46/201 (22%), Positives = 64/201 (31%), Gaps = 26/201 (12%) Query: 866 GPGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQ--LSH 923 GPG P P +S + G G P P T D P Q S Sbjct: 224 GPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGK---PIQGPTQTPQTDHAKLPLQRDASR 280 Query: 924 PPDMPNNMA-------ALEKPLSHPMQETMPHAGSSDQP-HPSIQQGLHVP--HPSSQSG 973 P ++ +L P P+Q+ P + QP H Q G P PS + Sbjct: 281 PQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTK 340 Query: 974 PPLHHSGAPPP---------PPSQP--PRQPPQAAPSSHPHSDLTFNPSSALEGQAGAQG 1022 P G P PP+QP P +PP S S P + + + Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKT 400 Query: 1023 ASDMPEPSLDLLPELTNPDEL 1043 + P P+ ++ P L Sbjct: 401 PAQQPGPAKPPTQQVGTPKPL 421 Score = 31.6 bits (70), Expect = 4.2 Identities = 16/36 (44%), Positives = 17/36 (47%), Gaps = 5/36 (13%) Query: 969 SSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSHPHS 1004 S+Q PP PPPPP PP PP P P S Sbjct: 2402 SAQPPPP-----PPPPPPPPPPPPPPPPPPLPPPTS 2432 Score = 31.6 bits (70), Expect = 4.2 Identities = 15/45 (33%), Positives = 21/45 (46%) Query: 497 RPPRPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPPFP 541 +PP P P P P P P PP+ P +S P + P + + P Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASP 2448 Score = 31.2 bits (69), Expect = 5.5 Identities = 16/46 (34%), Positives = 19/46 (41%) Query: 957 PSIQQGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSHP 1002 PS+ P P +S + PPPPP PP PP P P Sbjct: 2381 PSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPP 2426 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 68.9 bits (167), Expect = 2e-11 Identities = 78/336 (23%), Positives = 105/336 (31%), Gaps = 53/336 (15%) Query: 250 FGASYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATATATATATVAALQET 309 + AS P P P PP PP P + +A +A +A +T+ LQ Sbjct: 619 YTASQPSPPLPPPPPPPPPPPPPPPP--PPPPLPSQSAPSAGSAAPMFVKYSTITRLQNA 676 Query: 310 QNKDINQYGPMGP----TQAYNSQFMNQPG-----------PRGPASMGGSMNPASMAAG 354 + P P +Q+ Q + P P P S + PA A Sbjct: 677 SQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPS 736 Query: 355 MTPSGMSGPPMGMNQ-------------PRPPGISPFGTHGQRMPQQTYPGPRPQSLPIQ 401 + PP+ ++Q P PP +P P T P P Sbjct: 737 LPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAP 796 Query: 402 NIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQPSSGQYPP 461 + + P P P + P P Y P+PP P P +P Q S PP Sbjct: 797 VVTQAAPPTPT---PPVPPAKKQPAFPASYIPPSPPTPPVP--VPPPTLPKQQSFCAKPP 851 Query: 462 PTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHSPVPGNPTPPMT 521 P+ +Q Q PP P + + P PVP N P Sbjct: 852 PSPLSPVPSVVKQIASQ----------------FPPPPTPPAMESQPLKPVPANVAPQSP 895 Query: 522 PGSSIPPYLSPSQ--DVKPPFPPDIKPNMSALPPPP 555 P P PS P FPP + PPPP Sbjct: 896 PAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPP 931 Score = 56.6 bits (135), Expect = 1e-07 Identities = 117/478 (24%), Positives = 162/478 (33%), Gaps = 80/478 (16%) Query: 119 PPGKLPMQPPLSSMSSMKPTLSHSDGSF-PYDSVPWQQNTNQPPGSLSVVTTVWGVTNTS 177 PP P PPL S S+ P+ + F Y ++ QN +Q G+L T + + S Sbjct: 639 PPPPPPPPPPLPSQSA--PSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQS 696 Query: 178 -QSQVLGNPMANANNPMNPGGNPM-ASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPY-I 234 + Q+L P P P P S M P +P QFSA P + + + Sbjct: 697 VKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLP----QFSAPPPPLKIHQV 752 Query: 235 QQSMYGRPNYPGSGGFGASYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAAT 294 Q P P P P PA + PP P T PA + Sbjct: 753 QHITQVAPPTP---------PPPPPIPAPL--PPQAPPKPLVTIPAPTSTKTVAPVVTQA 801 Query: 295 ATATATATVAALQETQNKDINQYGPMGPTQAY---------NSQFMNQP--GPRGPASMG 343 A T T V ++ + P PT F +P P P Sbjct: 802 APPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSV 861 Query: 344 GSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQ-QTYPGPRPQSLPIQN 402 + TP M P+ +P P ++P Q P + P +P S+P+ + Sbjct: 862 VKQIASQFPPPPTPPAMESQPL---KPVPANVAP-----QSPPAVKAKPKWQPSSIPVPS 913 Query: 403 IKRPYPGEPNYGNQQYGPNSQF---PTQPGQYPAPNPPRPLTSPNYPGQ-----RMPSQP 454 P P P S P P PAP PP P T+ P + + S+ Sbjct: 914 PDFPPPP----------PESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKT 963 Query: 455 SS--GQYPPPTVNMGQYYK-------PEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVA 505 SS G+ PPPT K PE ++ G+ ++ P P A Sbjct: 964 SSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAA 1023 Query: 506 NYPHSPVPGNPTPPMTPG-------SSIPPYLS-PSQDVKPPFPPDIKPNMSALPPPP 555 P P N + PG S+ P LS +D FP P+ S PPPP Sbjct: 1024 --PPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPS--PPSDSDFPPPP 1077 Score = 46.6 bits (109), Expect = 1e-04 Identities = 41/156 (26%), Positives = 60/156 (38%), Gaps = 23/156 (14%) Query: 918 PPQLSHPPDMPNNMAA-LEKPLSHPMQETMP----HAGSSDQPHPSIQ-----QGLHVPH 967 P LS P + +A+ P + P E+ P A + Q P+++ Q +P Sbjct: 852 PSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPV 911 Query: 968 PSSQSGPPLHHSGA--PPPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEGQAGAQGASD 1025 PS PP S PPPPPS P PP P++ P D + +P + G Sbjct: 912 PSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKP 971 Query: 1026 MPEPSLDLL-----------PELTNPDELLSYLDPP 1050 P P + P+ + D L+S PP Sbjct: 972 PPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPP 1007 Score = 45.4 bits (106), Expect = 3e-04 Identities = 41/139 (29%), Positives = 52/139 (37%), Gaps = 12/139 (8%) Query: 420 PNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQPSSGQYPPPTVNMGQYYKPEQFNGQN 479 P+ P P P P PP P P P Q S PS+G P V + + + + Sbjct: 624 PSPPLPPPPPPPPPPPPPPPPPPPPLPSQ---SAPSAGSAAPMFVKYSTITRLQNASQHS 680 Query: 480 NTFSGSSYSNYSQGNVNRPPRPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPP 539 Q +P VP P P P PP TPGS++ L P+ P Sbjct: 681 GALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPP--PPPPPTPGSAMAQ-LKPA-----P 732 Query: 540 FPPDIKPNMSALPPPPANH 558 P + P SA PPP H Sbjct: 733 CAPSL-PQFSAPPPPLKIH 750 Score = 44.3 bits (103), Expect = 6e-04 Identities = 36/127 (28%), Positives = 54/127 (42%), Gaps = 12/127 (9%) Query: 939 SHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPP---- 994 S E+M +S P S Q + P+ +SQ PPL PPPPP PP PP Sbjct: 591 SKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLP 650 Query: 995 -QAAPSSHPHSDLTFNPSSALEGQAGAQGASDMPEP-------SLDLLPELTNPDELLSY 1046 Q+APS+ + + S+ Q +Q + + +P S + P++ P + Sbjct: 651 SQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVP 710 Query: 1047 LDPPDLP 1053 PP P Sbjct: 711 PPPPPPP 717 Score = 44.3 bits (103), Expect = 6e-04 Identities = 59/213 (27%), Positives = 73/213 (34%), Gaps = 42/213 (19%) Query: 867 PGPSPYPLPPPPGGTNSNDYSSQG----------------NNYQGHGNFDFPHGNPGGTS 910 P P P P PPPP S S G N Q G P P S Sbjct: 635 PPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQS 694 Query: 911 MN---------DFMHGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQ 961 + + + PP PP P + A KP P ++P S+ P I Q Sbjct: 695 QSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPA--PCAPSLPQF-SAPPPPLKIHQ 751 Query: 962 GLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEGQAGAQ 1021 H+ +Q PP PPPPP P PPQA P P + S+ Q Sbjct: 752 VQHI----TQVAPP-----TPPPPPPIPAPLPPQAPPK--PLVTIPAPTSTKTVAPVVTQ 800 Query: 1022 GASDMPEPSLDLLPELTNPDELLSYLDPPDLPS 1054 A P P + P P SY+ PP P+ Sbjct: 801 AAPPTPTPPVP--PAKKQPAFPASYI-PPSPPT 830 Score = 43.1 bits (100), Expect = 0.001 Identities = 48/201 (23%), Positives = 68/201 (33%), Gaps = 32/201 (15%) Query: 382 GQRMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLT 441 G ++ + + + P ++ P +P P P P P PP P Sbjct: 584 GTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPP-- 641 Query: 442 SPNYPGQRMPSQ--PSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPP 499 P P +PSQ PS+G P V + + + + Q +P Sbjct: 642 -PPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQ 700 Query: 500 RPVPVANYPHSPVPGNPTPPMTPGS------------SIPPYLSPSQDVK---------- 537 VP P P P PP TPGS S+P + +P +K Sbjct: 701 ILVPPNGVVPPPPP--PPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQV 758 Query: 538 -PPFPPDIKPNMSALPP--PP 555 PP PP P + LPP PP Sbjct: 759 APPTPPPPPPIPAPLPPQAPP 779 Score = 39.3 bits (90), Expect = 0.020 Identities = 54/205 (26%), Positives = 71/205 (34%), Gaps = 36/205 (17%) Query: 845 FKTMSP----SQMIMPNVMEMIAALGPGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFD 900 FK +P SQ + P ++ + P P P P PP PG + F Sbjct: 684 FKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQ--LKPAPCAPSLPQFS 741 Query: 901 FPHGNPGGTSMNDFMH----GPPQLSHPPDMPNNMA--ALEKPLSHPMQETMPHAGSSDQ 954 P P ++ H PP PP +P + A KPL T+P S+ Sbjct: 742 AP---PPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLV-----TIPAPTSTKT 793 Query: 955 PHPSIQQGLHV----PHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSH------PHS 1004 P + Q P P ++ P S PP PP+ P PP P P S Sbjct: 794 VAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPS 853 Query: 1005 DLTFNPSSALEGQAGAQGASDMPEP 1029 L+ PS Q AS P P Sbjct: 854 PLSPVPSVV------KQIASQFPPP 872 Score = 35.0 bits (79), Expect = 0.38 Identities = 47/190 (24%), Positives = 64/190 (33%), Gaps = 39/190 (20%) Query: 840 IPSKRFKTMSP-SQMIMPNVMEMIAALGPGPSPYPL-PPPPGGTNSNDYSSQGNNYQGHG 897 +PS F P S ++ P P PSP P PPPP T S G+ + Sbjct: 911 VPSPDFPPPPPESSLVFPP---------PPPSPVPAPPPPPPPTASPTPDKSGSPGKKTS 961 Query: 898 NFDFPHGN--PGGTSMNDFMHGPPQLSHP-PDMPNNMAALEK-----PLSHPMQETMPHA 949 P G P N + HP P P+ + + K P +ET+P Sbjct: 962 KTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPP 1021 Query: 950 GSSDQPHPSIQQGLHVPHPSSQ----------SG----------PPLHHSGAPPPPPSQP 989 + +P G+++P Q SG P S PPPPP Sbjct: 1022 AAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETE 1081 Query: 990 PRQPPQAAPS 999 PP P+ Sbjct: 1082 LPLPPIEIPA 1091 >gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] Length = 638 Score = 67.0 bits (162), Expect = 9e-11 Identities = 63/228 (27%), Positives = 84/228 (36%), Gaps = 32/228 (14%) Query: 339 PASMGGSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSL 398 PAS+G + PA+ P P N P PP + + Q P GP +S Sbjct: 326 PASVGSTSGPATTPLASAPR----PAAPANNPPPPSLM---STTQSRPPWMNSGPS-ESR 377 Query: 399 PIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQPSSG- 457 P + PG P G P +P P P +P Q P+ P Sbjct: 378 PYHGMHGGGPGGPGGG-------------PHSFPHPLPSLTGGHGGHPMQHNPNGPPPPW 424 Query: 458 -QYPPPTVNMG-----QYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHSP 511 Q PPP +N G + P +T GS QG PP P+ + P P Sbjct: 425 MQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPP 484 Query: 512 VPGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPPPPANHN 559 G P PP P +PP+ Q +PP PP +M++ P P N Sbjct: 485 PSGQPPPP--PSGPLPPW--QQQQQQPPPPPPPSSSMASSTPLPWQQN 528 Score = 57.4 bits (137), Expect = 7e-08 Identities = 74/286 (25%), Positives = 101/286 (35%), Gaps = 28/286 (9%) Query: 273 PADFTQPAAAAAAAAVAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMN 332 PA + A +A A A + + TQ++ + GP+++ M+ Sbjct: 326 PASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRP--PWMNSGPSESRPYHGMH 383 Query: 333 QPGPRGPASMGGSM-NPA-SMAAGMTPSGM----SGPPMGMNQPRPP----GISPFGTHG 382 GP GP S +P S+ G M +GPP QP PP G P G HG Sbjct: 384 GGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHG 443 Query: 383 QRMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTS 442 P Y G P + R + G+ G P P P P+ PP P + Sbjct: 444 PP-PMDQYLGSTPVG---SGVYRLHQGK---GMMPPPPMGMMPPPPPP-PSGQPPPPPSG 495 Query: 443 PNYPGQRMPSQPSSGQYPPPTVNMGQYYK-PEQFNGQNNTFSGSS-----YSNYSQGNVN 496 P P Q+ QP PPP+ +M P Q N T S + + Sbjct: 496 PLPPWQQQQQQPPPP--PPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAA 553 Query: 497 RPPRPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPPFPP 542 P P N P+P PP+ PG+ PP P PP Sbjct: 554 SPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIPP 599 Score = 43.5 bits (101), Expect = 0.001 Identities = 51/178 (28%), Positives = 59/178 (33%), Gaps = 45/178 (25%) Query: 864 ALGPGPS-PYPLPPPP---------------GGTNSNDYSSQ---GNNYQGHGNFDFPH- 903 A P P+ P PPPP G + S Y G G G FPH Sbjct: 341 ASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHP 400 Query: 904 -----GNPGGTSMNDFMHGPPQ-LSHPPDMPNNMAALEKPLSH----PMQETMP------ 947 G GG M +GPP PP P N P H PM + + Sbjct: 401 LPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGP--HPPGHHGPPPMDQYLGSTPVGS 458 Query: 948 -----HAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSS 1000 H G P P + G+ P P SG P P PP Q +QPP P S Sbjct: 459 GVYRLHQGKGMMPPPPM--GMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPS 514 Score = 38.9 bits (89), Expect = 0.026 Identities = 52/182 (28%), Positives = 63/182 (34%), Gaps = 43/182 (23%) Query: 111 HQKSRQSDPP--GKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVT 168 HQ PP G +P PP S P G P PWQQ QPP Sbjct: 464 HQGKGMMPPPPMGMMPPPPPPPSGQPPPPP----SGPLP----PWQQQQQQPPPP----- 510 Query: 169 TVWGVTNTSQSQVLGNPMANANNPMNPGGNPMASGMTTSNPGLNS-PQFAGQQQQFSAKA 227 S S P+ N + TT++ G S P + QQQQ +A A Sbjct: 511 -----PPPSSSMASSTPLPWQQN----------TTTTTTSAGTGSIPPW--QQQQAAAAA 553 Query: 228 GPAQPYIQQSMYGRPNYPG-----SGGFGASYPGGPNAPAGMGIPPH-----TRPPADFT 277 P P +Q + P PG G P P AGM IPP + DF Sbjct: 554 SPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIPPRGGDGPSHESEDFP 613 Query: 278 QP 279 +P Sbjct: 614 RP 615 Score = 37.4 bits (85), Expect = 0.076 Identities = 48/203 (23%), Positives = 61/203 (30%), Gaps = 22/203 (10%) Query: 866 GPGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPP 925 GP P+PLP GG + N P P MN H PP PP Sbjct: 393 GPHSFPHPLPSLTGGHGGHPMQHNPNGPPP------PWMQPPPPPMNQGPH-PPGHHGPP 445 Query: 926 DMPNNMAALEKPLS----HPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSGA 981 M + + H + MP P P P P S PP Sbjct: 446 PMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQ 505 Query: 982 PPPPPSQPPRQPPQAAPSSHPHSDLTFNPSSAL-------EGQAGAQGASDMPE----PS 1030 PPPP P + P + T S+ + QA A + P+ P+ Sbjct: 506 QPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPT 565 Query: 1031 LDLLPELTNPDELLSYLDPPDLP 1053 + LP P PP P Sbjct: 566 MVPLPPGVQPPLPPGAPPPPPPP 588 Score = 35.8 bits (81), Expect = 0.22 Identities = 34/117 (29%), Positives = 38/117 (32%), Gaps = 21/117 (17%) Query: 947 PHAGSSDQPHPSIQ-QGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSHPHSD 1005 P G PHP G H HP H+ PPPP QPP PP HP Sbjct: 390 PGGGPHSFPHPLPSLTGGHGGHPMQ------HNPNGPPPPWMQPP--PPPMNQGPHPPGH 441 Query: 1006 LTFNPSSALEGQAGA--------QGASDMPEPSLDLLPELTNPDELLSYLDPPDLPS 1054 P G QG MP P + ++P P PP PS Sbjct: 442 HGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPS----GQPPPPPS 494 Score = 34.7 bits (78), Expect = 0.49 Identities = 60/248 (24%), Positives = 84/248 (33%), Gaps = 44/248 (17%) Query: 183 GNPMA-NANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQSMYGR 241 G+PM N N P P P M N G + P G P Y+ + G Sbjct: 410 GHPMQHNPNGPPPPWMQPPPPPM---NQGPHPPGHHGPP--------PMDQYLGSTPVGS 458 Query: 242 PNYPGSGGFG-------ASYPGGPNAPAGMGIPPHTRPPADFTQ-----PAAAAAAAAVA 289 Y G G P P P+G PP + P + Q P ++++A Sbjct: 459 GVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMA 518 Query: 290 AAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMGGSMNPA 349 ++ T T T G + P Q + PG P G NP Sbjct: 519 SSTPLPWQQNTTTTTTSAGT--------GSIPPWQQQQAAAAASPG--APQMQG---NPT 565 Query: 350 SMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPG 409 + P G+ PP+ P PP P G+ G +P + GP +S ++ RP Sbjct: 566 MVPL---PPGVQ-PPLPPGAPPPPPPPPPGSAGMMIPPRGGDGPSHES---EDFPRPLVT 618 Query: 410 EPNYGNQQ 417 P QQ Sbjct: 619 LPGRQPQQ 626 Score = 33.9 bits (76), Expect = 0.84 Identities = 54/219 (24%), Positives = 68/219 (31%), Gaps = 59/219 (26%) Query: 826 PIKSDLHIKDDPDGIPSKRFKTMSPSQMIMPNVMEMIAALGPGPSPYPLPPPPGGTNSND 885 P D ++ P G S ++ M+ P M M+ P PS P PPP G Sbjct: 444 PPPMDQYLGSTPVG--SGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQ 501 Query: 886 YSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPMQE- 944 Q PP PP P++ A PL P Q+ Sbjct: 502 QQQQQ---------------------------PP----PPPPPSSSMASSTPL--PWQQN 528 Query: 945 ---TMPHAGSSDQPHPSIQQGLHVPHPSSQS--------------GPPLHHSGAPPPPPS 987 T AG+ P QQ P + PPL GAPPPPP Sbjct: 529 TTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLP-PGAPPPPPP 587 Query: 988 QPPRQ-----PPQAAPSSHPHSDLTFNPSSALEGQAGAQ 1021 PP PP+ S+ P L G+ Q Sbjct: 588 PPPGSAGMMIPPRGGDGPSHESEDFPRPLVTLPGRQPQQ 626 >gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] Length = 639 Score = 67.0 bits (162), Expect = 9e-11 Identities = 63/228 (27%), Positives = 84/228 (36%), Gaps = 32/228 (14%) Query: 339 PASMGGSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSL 398 PAS+G + PA+ P P N P PP + + Q P GP +S Sbjct: 326 PASVGSTSGPATTPLASAPR----PAAPANNPPPPSLM---STTQSRPPWMNSGPS-ESR 377 Query: 399 PIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQPSSG- 457 P + PG P G P +P P P +P Q P+ P Sbjct: 378 PYHGMHGGGPGGPGGG-------------PHSFPHPLPSLTGGHGGHPMQHNPNGPPPPW 424 Query: 458 -QYPPPTVNMG-----QYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHSP 511 Q PPP +N G + P +T GS QG PP P+ + P P Sbjct: 425 MQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPP 484 Query: 512 VPGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPPPPANHN 559 G P PP P +PP+ Q +PP PP +M++ P P N Sbjct: 485 PSGQPPPP--PSGPLPPW--QQQQQQPPPPPPPSSSMASSTPLPWQQN 528 Score = 66.2 bits (160), Expect = 2e-10 Identities = 81/299 (27%), Positives = 108/299 (36%), Gaps = 37/299 (12%) Query: 273 PADFTQPAAAAAAAAVAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMN 332 PA + A +A A A + + TQ++ + GP+++ M+ Sbjct: 326 PASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRP--PWMNSGPSESRPYHGMH 383 Query: 333 QPGPRGPASMGGSM-NPA-SMAAGMTPSGM----SGPPMGMNQPRPP----GISPFGTHG 382 GP GP S +P S+ G M +GPP QP PP G P G HG Sbjct: 384 GGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHG 443 Query: 383 QRMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTS 442 P Y G P + R + G+ G P P P P+ PP P + Sbjct: 444 PP-PMDQYLGSTPVG---SGVYRLHQGK---GMMPPPPMGMMPPPPPP-PSGQPPPPPSG 495 Query: 443 PNYPGQRMPSQPSSGQYPPPTVNMGQYYK-PEQFNGQNNTFSGSS-----YSNYSQGNVN 496 P P Q+ QP PPP+ +M P Q N T S + + Sbjct: 496 PLPPWQQQQQQPPPP--PPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAA 553 Query: 497 RPPRPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPPPP 555 P P N P+P PP+ PG+ PP PP PP M A PPPP Sbjct: 554 SPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPP---------PPPPPGSAGMMYAPPPPP 603 Score = 43.5 bits (101), Expect = 0.001 Identities = 51/178 (28%), Positives = 59/178 (33%), Gaps = 45/178 (25%) Query: 864 ALGPGPS-PYPLPPPP---------------GGTNSNDYSSQ---GNNYQGHGNFDFPH- 903 A P P+ P PPPP G + S Y G G G FPH Sbjct: 341 ASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHP 400 Query: 904 -----GNPGGTSMNDFMHGPPQ-LSHPPDMPNNMAALEKPLSH----PMQETMP------ 947 G GG M +GPP PP P N P H PM + + Sbjct: 401 LPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGP--HPPGHHGPPPMDQYLGSTPVGS 458 Query: 948 -----HAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSS 1000 H G P P + G+ P P SG P P PP Q +QPP P S Sbjct: 459 GVYRLHQGKGMMPPPPM--GMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPS 514 Score = 38.5 bits (88), Expect = 0.034 Identities = 51/175 (29%), Positives = 61/175 (34%), Gaps = 40/175 (22%) Query: 111 HQKSRQSDPP--GKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVT 168 HQ PP G +P PP S P G P PWQQ QPP Sbjct: 464 HQGKGMMPPPPMGMMPPPPPPPSGQPPPPP----SGPLP----PWQQQQQQPPPP----- 510 Query: 169 TVWGVTNTSQSQVLGNPMANANNPMNPGGNPMASGMTTSNPGLNS-PQFAGQQQQFSAKA 227 S S P+ N + TT++ G S P + QQQQ +A A Sbjct: 511 -----PPPSSSMASSTPLPWQQN----------TTTTTTSAGTGSIPPW--QQQQAAAAA 553 Query: 228 GPAQPYIQQSMYGRPNYPGSG---GFGASYPGGPNAPAGMGI----PPHTRPPAD 275 P P +Q + P PG GA P P P G+ PP PP D Sbjct: 554 SPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMD 608 Score = 37.4 bits (85), Expect = 0.076 Identities = 48/203 (23%), Positives = 61/203 (30%), Gaps = 22/203 (10%) Query: 866 GPGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPP 925 GP P+PLP GG + N P P MN H PP PP Sbjct: 393 GPHSFPHPLPSLTGGHGGHPMQHNPNGPPP------PWMQPPPPPMNQGPH-PPGHHGPP 445 Query: 926 DMPNNMAALEKPLS----HPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSGA 981 M + + H + MP P P P P S PP Sbjct: 446 PMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQ 505 Query: 982 PPPPPSQPPRQPPQAAPSSHPHSDLTFNPSSAL-------EGQAGAQGASDMPE----PS 1030 PPPP P + P + T S+ + QA A + P+ P+ Sbjct: 506 QPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPT 565 Query: 1031 LDLLPELTNPDELLSYLDPPDLP 1053 + LP P PP P Sbjct: 566 MVPLPPGVQPPLPPGAPPPPPPP 588 Score = 35.8 bits (81), Expect = 0.22 Identities = 34/117 (29%), Positives = 38/117 (32%), Gaps = 21/117 (17%) Query: 947 PHAGSSDQPHPSIQ-QGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSHPHSD 1005 P G PHP G H HP H+ PPPP QPP PP HP Sbjct: 390 PGGGPHSFPHPLPSLTGGHGGHPMQ------HNPNGPPPPWMQPP--PPPMNQGPHPPGH 441 Query: 1006 LTFNPSSALEGQAGA--------QGASDMPEPSLDLLPELTNPDELLSYLDPPDLPS 1054 P G QG MP P + ++P P PP PS Sbjct: 442 HGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPS----GQPPPPPS 494 Score = 35.8 bits (81), Expect = 0.22 Identities = 49/174 (28%), Positives = 59/174 (33%), Gaps = 55/174 (31%) Query: 113 KSRQSDPPGKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWG 172 + +Q PP P PP SSM+S P +PWQQNT + TT G Sbjct: 501 QQQQQQPP---PPPPPSSSMASSTP-------------LPWQQNT-------TTTTTSAG 537 Query: 173 VTNTSQSQVLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQP 232 + Q A + GNP M PG+ P G A P P Sbjct: 538 TGSIPPWQQQQAAAAASPGAPQMQGNPT---MVPLPPGVQPPLPPG--------APPPPP 586 Query: 233 YIQQSMYGRPNYPGSGGFGASYPGGPNAP---------AGMGI---PPHTRPPA 274 P PGS G + P P P GMG+ PP PPA Sbjct: 587 ---------PPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPA 631 Score = 35.0 bits (79), Expect = 0.38 Identities = 52/207 (25%), Positives = 65/207 (31%), Gaps = 61/207 (29%) Query: 826 PIKSDLHIKDDPDGIPSKRFKTMSPSQMIMPNVMEMIAALGPGPSPYPLPPPPGGTNSND 885 P D ++ P G S ++ M+ P M M+ P PS P PPP G Sbjct: 444 PPPMDQYLGSTPVG--SGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQ 501 Query: 886 YSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPMQE- 944 Q PP PP P++ A PL P Q+ Sbjct: 502 QQQQQ---------------------------PP----PPPPPSSSMASSTPL--PWQQN 528 Query: 945 ---TMPHAGSSDQPHPSIQQGLHVPHPSSQS--------------GPPLHHSGAPPPPPS 987 T AG+ P QQ P + PPL GAPPPPP Sbjct: 529 TTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLP-PGAPPPPPP 587 Query: 988 QPP-------RQPPQAAPSSHPHSDLT 1007 PP PP P P + +T Sbjct: 588 PPPGSAGMMYAPPPPPPPPMDPSNFVT 614 >gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo sapiens] Length = 2231 Score = 67.0 bits (162), Expect = 9e-11 Identities = 110/411 (26%), Positives = 155/411 (37%), Gaps = 83/411 (20%) Query: 193 MNPGGNPMAS--GMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQSMYGRPNYPGSGGF 250 M PGG AS + +FAGQ Q S A P + Q + P + Sbjct: 322 MGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSG----ATPTLNQLLTSPS--PMMRSY 375 Query: 251 GASYP--GGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAA---------TATATA 299 G SYP P+AP PP ++P + Q AAA AAA AAA A A Sbjct: 376 GGSYPEYSSPSAPP----PPPSQPQS---QAAAAGAAAGGQQAAAGMGLGKDMGAQYAAA 428 Query: 300 TATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGP-RGPASMGGSMNPASMAAGMTP- 357 + AA Q+ + ++ G GPT + P + P G NP S +P Sbjct: 429 SPAWAAAQQRSHPAMSP-GTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPY 487 Query: 358 -SGMSGPP-----------------MGMNQPR---PP-----GISPFGTHGQR-----MP 386 G GPP GM P+ PP G+S + GQ+ P Sbjct: 488 PGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQP 547 Query: 387 QQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPN--------PPR 438 Q + P+ Q LP Q+ +R Y + + + YG SQ P PG+ PN R Sbjct: 548 QPPHLPPQAQYLPSQSQQR-YQPQQDMSQEGYGTRSQPPLAPGK---PNHEDLNLIQQER 603 Query: 439 PLTSPNYPGQ--RMPSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVN 496 P + P+ G +P+ + + + + +Q N + FS + + S Sbjct: 604 PSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGG 663 Query: 497 RPPRPV--PVANY-----PHSP--VPGNPTPPMTPGSSIPPYLSPSQDVKP 538 P PV PV + P SP +PG+ PP PGS P+ P Sbjct: 664 PSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSP 714 Score = 57.8 bits (138), Expect = 5e-08 Identities = 110/475 (23%), Positives = 149/475 (31%), Gaps = 64/475 (13%) Query: 116 QSDPPGKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWGVTN 175 Q+DPPG + P + + G + + + T QPP V G Sbjct: 112 QADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLG-ALGTQQPP-----VAVPGGGGG 165 Query: 176 TSQSQVLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGP--AQPY 233 + N +A P + G A + G SP +A AG + Sbjct: 166 PAAVPEFNNYYGSAA-PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDP 224 Query: 234 IQQSMYGRPNY----------PGSGGFGASYPGGPNAPAGMGIPPHTRPPADFTQPAAAA 283 +Q S G PN PG+GG G GG G G A A Sbjct: 225 LQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGG--------GGGGAGAGGA 276 Query: 284 AAAAVAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMG 343 A AVAAAAA A A A + YG + + M PG G AS+ Sbjct: 277 GAGAVAAAAAAAAAAAGGGGGGGYGGSSAG---YGVLSSPRQQGGGMMMGPGGGGAASLS 333 Query: 344 GSMNPASMAAGMTPSGMSGPPMG----MNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLP 399 + ++ +G + P G +NQ ++G P+ + P P P Sbjct: 334 KAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPP-P 392 Query: 400 IQNIKRPYPGEPNYGNQQYGPNSQFPTQPG-QYPAPNP--------PRPLTSPNYPGQRM 450 Q + G QQ G QY A +P P SP PG M Sbjct: 393 SQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTM 452 Query: 451 PSQPSSGQYP-----PPTVNMGQYYKPEQFNGQNNTFSGSSY-----SNYSQGNVNRPPR 500 S P P MG P Q++ + G SY Y G R P Sbjct: 453 GRSQGSPMDPMVMKRPQLYGMGS--NPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPG 510 Query: 501 PVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQD---VKPPFPPDIKPNMSALP 552 + YP + PP + Y Q + P PP + P LP Sbjct: 511 AMAGMQYPQQQM-----PPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLP 560 Score = 56.6 bits (135), Expect = 1e-07 Identities = 100/393 (25%), Positives = 142/393 (36%), Gaps = 76/393 (19%) Query: 194 NPGGNPMAS----GMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQSMYGRPNYPGSGG 249 NP P S G + PG Q + A AG P QQ M P Y G Sbjct: 476 NPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYP--QQQM--PPQYGQQGV 531 Query: 250 FGASYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATATATATATVAALQET 309 G G + PPH P A + + + T + A + Sbjct: 532 SGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKP 591 Query: 310 QNKDINQYGPMGP----------------TQAYNSQFMNQPGPRGPASMGGSMNPA---- 349 ++D+N P T+A S ++ G +S G NPA Sbjct: 592 NHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASG--STSSQGDQSNPAQSPF 649 Query: 350 ---------SMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLPI 400 S+ G +PS + G P+G NQ R ISP G +MP Q PG + +S Sbjct: 650 SPHASPHLSSIPGGPSPSPV-GSPVGSNQSRSGPISPASIPGSQMPPQP-PGSQSESSSH 707 Query: 401 QNIKR-PYPGEPNY--GNQ------QYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMP 451 + + P P E + G Q QYGP T P P P+P + + Q+ Sbjct: 708 PALSQSPMPQERGFMAGTQRNPQMAQYGPQQ---TGPSMSPHPSPGGQMHAGISSFQQSN 764 Query: 452 SQ----PSSGQYPPPTVNMGQYYKPEQFNG-QNNTFSGS------SYSNYSQG-NVNRPP 499 S P QY P G Y +P ++G + ++SG S +N G ++P Sbjct: 765 SSGTYGPQMSQYGP----QGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPC 820 Query: 500 RPVPVANYP-----HSPVPGNPT--PPMTPGSS 525 VP+ P + P PGN + P +PG S Sbjct: 821 GAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMS 853 Score = 54.7 bits (130), Expect = 5e-07 Identities = 101/408 (24%), Positives = 138/408 (33%), Gaps = 113/408 (27%) Query: 120 PGKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWGVTNTSQS 179 P P+ P+ S S +S + S+P Q QPPGS S ++ ++ + Sbjct: 664 PSPSPVGSPVGSNQSRSGPISPA-------SIPGSQMPPQPPGSQSESSSHPALSQSPMP 716 Query: 180 QVLGNPMANANNPMNPGGNPMASGMTTS-NPGLNSPQFAG----QQQQFSAKAGP-AQPY 233 Q G NP P +G + S +P AG QQ S GP Y Sbjct: 717 QERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQY 776 Query: 234 IQQSMYGRP---------NYPGSG-GFGAS-----YPGGPNAPAGMGIP----------- 267 Q Y RP +Y G G G G S + GP+ P G +P Sbjct: 777 GPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCG-AVPLGRMPSAGMQN 835 Query: 268 ----------------------PHTRPPADFTQPAAAAAAAAVAAAAATATATATATVAA 305 P PP A AAAAV AAA + + + Sbjct: 836 RPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPG 895 Query: 306 LQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMGGSMNPASMAAGMTPSGMSGPPM 365 + NQ G M + Y +QP + M P SMA M S S + Sbjct: 896 M--------NQSGLMASSSPY-----SQPMNNSSSLMNTQAPPYSMAPAMVNS--SAASV 940 Query: 366 GMNQPRPPGIS--PFGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGPNSQ 423 G+ PG S P + T P+P+S + +Y +Q SQ Sbjct: 941 GLADMMSPGESKLPLPLKADGKEEGT---PQPES----------KSKDSYSSQGI---SQ 984 Query: 424 FPTQPGQYPAPNPPRP---------------LTSPNYPGQRMPSQPSS 456 PT PG P P+P P ++SP +P + PS P S Sbjct: 985 PPT-PGNLPVPSPMSPSSASISSFHGDESDSISSPGWP--KTPSSPKS 1029 Score = 37.7 bits (86), Expect = 0.058 Identities = 51/215 (23%), Positives = 77/215 (35%), Gaps = 19/215 (8%) Query: 824 PVPIKSDLHIKDDPDGIPSKRFKTMSPSQM-IMPNVMEMIAALGPGPSPYPLPPPPGGTN 882 P ++ L G S + +P+Q P+ ++++ GPSP P+ P G Sbjct: 618 PTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQ 677 Query: 883 SNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPM 942 S + G P PG S + P LS P MP + +P Sbjct: 678 SRSGPISPASIPGS---QMPPQPPGSQSESS---SHPALSQSP-MPQERGFMAGTQRNPQ 730 Query: 943 --QETMPHAGSSDQPHPSIQQGLHVPHPSSQS-------GPPLHHSGAPPPPPSQPPR-Q 992 Q G S PHPS +H S Q GP + G P S+PP Sbjct: 731 MAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYG-PQGNYSRPPAYS 789 Query: 993 PPQAAPSSHPHSDLTFNPSSALEGQAGAQGASDMP 1027 +A S P + + ++ + GQ +Q +P Sbjct: 790 GVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVP 824 Score = 36.6 bits (83), Expect = 0.13 Identities = 47/192 (24%), Positives = 66/192 (34%), Gaps = 42/192 (21%) Query: 867 PGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPPD 926 PG P PP GG Y Q N Y+ H D M+GPP H D Sbjct: 1329 PGQGPPSGQPPYGGHQPGLYPQQPN-YKRH---------------MDGMYGPPAKRHEGD 1372 Query: 927 MPNNMAALEKPLSHPMQETMPHAGSS-----------DQPHPSIQQGLHVPHPSSQSGPP 975 M N S QE G S P+P ++ + P G P Sbjct: 1373 MYN------MQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIP 1426 Query: 976 LHHSGAP-PPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEGQAGAQGASDMPEPSLDLL 1034 G P S+ P+Q AA + P+ P +G G A P P ++ Sbjct: 1427 PQMMGGPLQSSSSEGPQQNMWAARNDMPY------PYQNRQGPGGPTQAP--PYPGMNRT 1478 Query: 1035 PELTNPDELLSY 1046 ++ PD+ +++ Sbjct: 1479 DDMMVPDQRINH 1490 Score = 34.3 bits (77), Expect = 0.64 Identities = 97/419 (23%), Positives = 133/419 (31%), Gaps = 98/419 (23%) Query: 117 SDPPGKL-PMQPPLSSMSSMKPTLSH-SDGSFPY-----DSVPWQQNTNQP--------- 160 S P G++ PMQ SS S+ S SD SFP + P+QQ + P Sbjct: 1199 STPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYE 1258 Query: 161 ------------PGSLSVVTTVWGVTNTSQSQVLGNPMANANNPMNPGGN---------- 198 PGS T + N+S + + A + + G Sbjct: 1259 PNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYD 1318 Query: 199 ----PMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQ---SMYGRPNYPGSGG-- 249 P P P + G Q P QP ++ MYG P G Sbjct: 1319 RRHEPYGQQYPGQGPPSGQPPYGGHQPGLY----PQQPNYKRHMDGMYGPPAKRHEGDMY 1374 Query: 250 --------------FGASYPGGPNAPAGMGIP-PHTRP----PADFTQPAAAAAAAAVAA 290 +G SY G P P P++R P Sbjct: 1375 NMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPL 1434 Query: 291 AAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQ------PGPR------G 338 ++++ AA + N+ GP GPTQA MN+ P R Sbjct: 1435 QSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQW 1494 Query: 339 PASMGGSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSL 398 P+ + S +A M P ++ PP Q PP + H R P P +SL Sbjct: 1495 PSHVSQRQPYMSSSASMQP--ITRPPQPSYQ-TPPSLP---NHISRAPS---PASFQRSL 1545 Query: 399 PIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPP---RPLTSPNYPGQRMPSQP 454 + P P+ Q+ P PT P P PP R +T P PG SQP Sbjct: 1546 ENRMSPSKSPFLPSMKMQKVMPT--VPTSQVTGPPPQPPPIRREITFP--PGSVEASQP 1600 Score = 33.1 bits (74), Expect = 1.4 Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 7/59 (11%) Query: 949 AGSSDQPH---PSIQQGLHVPHPSSQSG----PPLHHSGAPPPPPSQPPRQPPQAAPSS 1000 AG + P P++ Q L P P +S P APPPPPSQP Q A ++ Sbjct: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAA 406 Score = 32.0 bits (71), Expect = 3.2 Identities = 36/155 (23%), Positives = 58/155 (37%), Gaps = 33/155 (21%) Query: 866 GPGP-SPYPLPPPPGGTNSNDYSSQG---NNYQGHGNFDFPHGN-------------PGG 908 GPG + +PP G SS+G N + + +P+ N PG Sbjct: 1416 GPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGM 1475 Query: 909 TSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHP 968 +D M +++H P++++ + P+ SS S+Q P P Sbjct: 1476 NRTDDMMVPDQRINHESQWPSHVS-----------QRQPYMSSS----ASMQPITRPPQP 1520 Query: 969 SSQSGPPL-HHSGAPPPPPSQPPRQPPQAAPSSHP 1002 S Q+ P L +H P P S + +PS P Sbjct: 1521 SYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSP 1555 Score = 31.6 bits (70), Expect = 4.2 Identities = 38/155 (24%), Positives = 56/155 (36%), Gaps = 28/155 (18%) Query: 886 YSSQGNNYQG------HGNFDFPHGN-----PGGTSMN----DFMHGPPQLSHPPDMPNN 930 Y+ G +Y G G + +P+ PG + M GP Q S N Sbjct: 1386 YNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQN 1445 Query: 931 MAALEKPLSHPMQETMPHAGSSDQP-HPSIQQ--GLHVPH---------PSSQSG-PPLH 977 M A + +P Q G + P +P + + + VP PS S P Sbjct: 1446 MWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYM 1505 Query: 978 HSGAPPPPPSQPPRQPPQAAPSSHPHSDLTFNPSS 1012 S A P ++PP+ Q PS H +P+S Sbjct: 1506 SSSASMQPITRPPQPSYQTPPSLPNHISRAPSPAS 1540 >gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo sapiens] Length = 2178 Score = 67.0 bits (162), Expect = 9e-11 Identities = 110/411 (26%), Positives = 155/411 (37%), Gaps = 83/411 (20%) Query: 193 MNPGGNPMAS--GMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQSMYGRPNYPGSGGF 250 M PGG AS + +FAGQ Q S A P + Q + P + Sbjct: 322 MGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSG----ATPTLNQLLTSPS--PMMRSY 375 Query: 251 GASYP--GGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAA---------TATATA 299 G SYP P+AP PP ++P + Q AAA AAA AAA A A Sbjct: 376 GGSYPEYSSPSAPP----PPPSQPQS---QAAAAGAAAGGQQAAAGMGLGKDMGAQYAAA 428 Query: 300 TATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGP-RGPASMGGSMNPASMAAGMTP- 357 + AA Q+ + ++ G GPT + P + P G NP S +P Sbjct: 429 SPAWAAAQQRSHPAMSP-GTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPY 487 Query: 358 -SGMSGPP-----------------MGMNQPR---PP-----GISPFGTHGQR-----MP 386 G GPP GM P+ PP G+S + GQ+ P Sbjct: 488 PGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQP 547 Query: 387 QQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPN--------PPR 438 Q + P+ Q LP Q+ +R Y + + + YG SQ P PG+ PN R Sbjct: 548 QPPHLPPQAQYLPSQSQQR-YQPQQDMSQEGYGTRSQPPLAPGK---PNHEDLNLIQQER 603 Query: 439 PLTSPNYPGQ--RMPSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVN 496 P + P+ G +P+ + + + + +Q N + FS + + S Sbjct: 604 PSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGG 663 Query: 497 RPPRPV--PVANY-----PHSP--VPGNPTPPMTPGSSIPPYLSPSQDVKP 538 P PV PV + P SP +PG+ PP PGS P+ P Sbjct: 664 PSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSP 714 Score = 57.8 bits (138), Expect = 5e-08 Identities = 110/475 (23%), Positives = 149/475 (31%), Gaps = 64/475 (13%) Query: 116 QSDPPGKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWGVTN 175 Q+DPPG + P + + G + + + T QPP V G Sbjct: 112 QADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLG-ALGTQQPP-----VAVPGGGGG 165 Query: 176 TSQSQVLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGP--AQPY 233 + N +A P + G A + G SP +A AG + Sbjct: 166 PAAVPEFNNYYGSAA-PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDP 224 Query: 234 IQQSMYGRPNY----------PGSGGFGASYPGGPNAPAGMGIPPHTRPPADFTQPAAAA 283 +Q S G PN PG+GG G GG G G A A Sbjct: 225 LQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGG--------GGGGAGAGGA 276 Query: 284 AAAAVAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMG 343 A AVAAAAA A A A + YG + + M PG G AS+ Sbjct: 277 GAGAVAAAAAAAAAAAGGGGGGGYGGSSAG---YGVLSSPRQQGGGMMMGPGGGGAASLS 333 Query: 344 GSMNPASMAAGMTPSGMSGPPMG----MNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLP 399 + ++ +G + P G +NQ ++G P+ + P P P Sbjct: 334 KAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPP-P 392 Query: 400 IQNIKRPYPGEPNYGNQQYGPNSQFPTQPG-QYPAPNP--------PRPLTSPNYPGQRM 450 Q + G QQ G QY A +P P SP PG M Sbjct: 393 SQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTM 452 Query: 451 PSQPSSGQYP-----PPTVNMGQYYKPEQFNGQNNTFSGSSY-----SNYSQGNVNRPPR 500 S P P MG P Q++ + G SY Y G R P Sbjct: 453 GRSQGSPMDPMVMKRPQLYGMGS--NPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPG 510 Query: 501 PVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQD---VKPPFPPDIKPNMSALP 552 + YP + PP + Y Q + P PP + P LP Sbjct: 511 AMAGMQYPQQQM-----PPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLP 560 Score = 56.6 bits (135), Expect = 1e-07 Identities = 100/393 (25%), Positives = 142/393 (36%), Gaps = 76/393 (19%) Query: 194 NPGGNPMAS----GMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQSMYGRPNYPGSGG 249 NP P S G + PG Q + A AG P QQ M P Y G Sbjct: 476 NPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYP--QQQM--PPQYGQQGV 531 Query: 250 FGASYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATATATATATVAALQET 309 G G + PPH P A + + + T + A + Sbjct: 532 SGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKP 591 Query: 310 QNKDINQYGPMGP----------------TQAYNSQFMNQPGPRGPASMGGSMNPA---- 349 ++D+N P T+A S ++ G +S G NPA Sbjct: 592 NHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASG--STSSQGDQSNPAQSPF 649 Query: 350 ---------SMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLPI 400 S+ G +PS + G P+G NQ R ISP G +MP Q PG + +S Sbjct: 650 SPHASPHLSSIPGGPSPSPV-GSPVGSNQSRSGPISPASIPGSQMPPQP-PGSQSESSSH 707 Query: 401 QNIKR-PYPGEPNY--GNQ------QYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMP 451 + + P P E + G Q QYGP T P P P+P + + Q+ Sbjct: 708 PALSQSPMPQERGFMAGTQRNPQMAQYGPQQ---TGPSMSPHPSPGGQMHAGISSFQQSN 764 Query: 452 SQ----PSSGQYPPPTVNMGQYYKPEQFNG-QNNTFSGS------SYSNYSQG-NVNRPP 499 S P QY P G Y +P ++G + ++SG S +N G ++P Sbjct: 765 SSGTYGPQMSQYGP----QGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPC 820 Query: 500 RPVPVANYP-----HSPVPGNPT--PPMTPGSS 525 VP+ P + P PGN + P +PG S Sbjct: 821 GAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMS 853 Score = 45.8 bits (107), Expect = 2e-04 Identities = 77/311 (24%), Positives = 103/311 (33%), Gaps = 77/311 (24%) Query: 120 PGKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWGVTNTSQS 179 P P+ P+ S S +S + S+P Q QPPGS S ++ ++ + Sbjct: 664 PSPSPVGSPVGSNQSRSGPISPA-------SIPGSQMPPQPPGSQSESSSHPALSQSPMP 716 Query: 180 QVLGNPMANANNPMNPGGNPMASGMTTS-NPGLNSPQFAG----QQQQFSAKAGP-AQPY 233 Q G NP P +G + S +P AG QQ S GP Y Sbjct: 717 QERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQY 776 Query: 234 IQQSMYGRP---------NYPGSG-GFGAS-----YPGGPNAPAGMGIP----------- 267 Q Y RP +Y G G G G S + GP+ P G +P Sbjct: 777 GPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCG-AVPLGRMPSAGMQN 835 Query: 268 ----------------------PHTRPPADFTQPAAAAAAAAVAAAAATATATATATVAA 305 P PP A AAAAV AAA + + + Sbjct: 836 RPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPG 895 Query: 306 LQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMGGSMNPASMAAGMTPSGMSGPPM 365 + NQ G M + Y +QP + M P SMA M S S + Sbjct: 896 M--------NQSGLMASSSPY-----SQPMNNSSSLMNTQAPPYSMAPAMVNS--SAASV 940 Query: 366 GMNQPRPPGIS 376 G+ PG S Sbjct: 941 GLADMMSPGES 951 Score = 45.4 bits (106), Expect = 3e-04 Identities = 77/321 (23%), Positives = 121/321 (37%), Gaps = 32/321 (9%) Query: 160 PPGSLSVVTTVWGVTNTSQSQVLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQ 219 P G+ + +++ + ++ SQ + +NP +P AS +S PG SP G Sbjct: 618 PTGTEATLSSAVSASGSTSSQ------GDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGS 671 Query: 220 QQQFS-AKAGPAQPYIQQSMYGRPNYPGSGGFGASYPGGPNAPAGM--GIPPHTRPPADF 276 + +++GP P P PGS +S+P +P G T+ Sbjct: 672 PVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQM 731 Query: 277 TQPAAAAAAAAVAAAAATATATATATVAALQE-----TQNKDINQYGPMGPTQ---AYN- 327 Q +++ + A +++ Q+ T ++QYGP G AY+ Sbjct: 732 AQYGPQQTGPSMSPHPSPG-GQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSG 790 Query: 328 --SQFMNQPGPRGPASMGGSMNPA--SMAAGMTPSGMSGPPMGM-NQPRPPGISPFGTHG 382 S + PGP S M+ S G P G P GM N+P P +S Sbjct: 791 VPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRM-PSAGMQNRPFPGNMSSMTPSS 849 Query: 383 QRMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTS 442 M QQ PG P P+ + R E Q NS ++ G +P N + S Sbjct: 850 PGMSQQGGPGMGP---PMPTVNRK-AQEAAAAVMQAAANSA-QSRQGSFPGMNQSGLMAS 904 Query: 443 PNYPGQRMPSQPS--SGQYPP 461 + Q M + S + Q PP Sbjct: 905 SSPYSQPMNNSSSLMNTQAPP 925 Score = 37.7 bits (86), Expect = 0.058 Identities = 51/215 (23%), Positives = 77/215 (35%), Gaps = 19/215 (8%) Query: 824 PVPIKSDLHIKDDPDGIPSKRFKTMSPSQM-IMPNVMEMIAALGPGPSPYPLPPPPGGTN 882 P ++ L G S + +P+Q P+ ++++ GPSP P+ P G Sbjct: 618 PTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQ 677 Query: 883 SNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPM 942 S + G P PG S + P LS P MP + +P Sbjct: 678 SRSGPISPASIPGS---QMPPQPPGSQSESS---SHPALSQSP-MPQERGFMAGTQRNPQ 730 Query: 943 --QETMPHAGSSDQPHPSIQQGLHVPHPSSQS-------GPPLHHSGAPPPPPSQPPR-Q 992 Q G S PHPS +H S Q GP + G P S+PP Sbjct: 731 MAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYG-PQGNYSRPPAYS 789 Query: 993 PPQAAPSSHPHSDLTFNPSSALEGQAGAQGASDMP 1027 +A S P + + ++ + GQ +Q +P Sbjct: 790 GVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVP 824 Score = 36.6 bits (83), Expect = 0.13 Identities = 47/192 (24%), Positives = 66/192 (34%), Gaps = 42/192 (21%) Query: 867 PGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPPD 926 PG P PP GG Y Q N Y+ H D M+GPP H D Sbjct: 1276 PGQGPPSGQPPYGGHQPGLYPQQPN-YKRH---------------MDGMYGPPAKRHEGD 1319 Query: 927 MPNNMAALEKPLSHPMQETMPHAGSS-----------DQPHPSIQQGLHVPHPSSQSGPP 975 M N S QE G S P+P ++ + P G P Sbjct: 1320 MYN------MQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIP 1373 Query: 976 LHHSGAP-PPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEGQAGAQGASDMPEPSLDLL 1034 G P S+ P+Q AA + P+ P +G G A P P ++ Sbjct: 1374 PQMMGGPLQSSSSEGPQQNMWAARNDMPY------PYQNRQGPGGPTQAP--PYPGMNRT 1425 Query: 1035 PELTNPDELLSY 1046 ++ PD+ +++ Sbjct: 1426 DDMMVPDQRINH 1437 Score = 34.3 bits (77), Expect = 0.64 Identities = 97/419 (23%), Positives = 133/419 (31%), Gaps = 98/419 (23%) Query: 117 SDPPGKL-PMQPPLSSMSSMKPTLSH-SDGSFPY-----DSVPWQQNTNQP--------- 160 S P G++ PMQ SS S+ S SD SFP + P+QQ + P Sbjct: 1146 STPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYE 1205 Query: 161 ------------PGSLSVVTTVWGVTNTSQSQVLGNPMANANNPMNPGGN---------- 198 PGS T + N+S + + A + + G Sbjct: 1206 PNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYD 1265 Query: 199 ----PMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQ---SMYGRPNYPGSGG-- 249 P P P + G Q P QP ++ MYG P G Sbjct: 1266 RRHEPYGQQYPGQGPPSGQPPYGGHQPGLY----PQQPNYKRHMDGMYGPPAKRHEGDMY 1321 Query: 250 --------------FGASYPGGPNAPAGMGIP-PHTRP----PADFTQPAAAAAAAAVAA 290 +G SY G P P P++R P Sbjct: 1322 NMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPL 1381 Query: 291 AAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQ------PGPR------G 338 ++++ AA + N+ GP GPTQA MN+ P R Sbjct: 1382 QSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQW 1441 Query: 339 PASMGGSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSL 398 P+ + S +A M P ++ PP Q PP + H R P P +SL Sbjct: 1442 PSHVSQRQPYMSSSASMQP--ITRPPQPSYQ-TPPSLP---NHISRAPS---PASFQRSL 1492 Query: 399 PIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPP---RPLTSPNYPGQRMPSQP 454 + P P+ Q+ P PT P P PP R +T P PG SQP Sbjct: 1493 ENRMSPSKSPFLPSMKMQKVMPT--VPTSQVTGPPPQPPPIRREITFP--PGSVEASQP 1547 Score = 33.1 bits (74), Expect = 1.4 Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 7/59 (11%) Query: 949 AGSSDQPH---PSIQQGLHVPHPSSQSG----PPLHHSGAPPPPPSQPPRQPPQAAPSS 1000 AG + P P++ Q L P P +S P APPPPPSQP Q A ++ Sbjct: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAA 406 Score = 32.0 bits (71), Expect = 3.2 Identities = 36/155 (23%), Positives = 58/155 (37%), Gaps = 33/155 (21%) Query: 866 GPGP-SPYPLPPPPGGTNSNDYSSQG---NNYQGHGNFDFPHGN-------------PGG 908 GPG + +PP G SS+G N + + +P+ N PG Sbjct: 1363 GPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGM 1422 Query: 909 TSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHP 968 +D M +++H P++++ + P+ SS S+Q P P Sbjct: 1423 NRTDDMMVPDQRINHESQWPSHVS-----------QRQPYMSSS----ASMQPITRPPQP 1467 Query: 969 SSQSGPPL-HHSGAPPPPPSQPPRQPPQAAPSSHP 1002 S Q+ P L +H P P S + +PS P Sbjct: 1468 SYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSP 1502 Score = 31.6 bits (70), Expect = 4.2 Identities = 38/155 (24%), Positives = 56/155 (36%), Gaps = 28/155 (18%) Query: 886 YSSQGNNYQG------HGNFDFPHGN-----PGGTSMN----DFMHGPPQLSHPPDMPNN 930 Y+ G +Y G G + +P+ PG + M GP Q S N Sbjct: 1333 YNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQN 1392 Query: 931 MAALEKPLSHPMQETMPHAGSSDQP-HPSIQQ--GLHVPH---------PSSQSG-PPLH 977 M A + +P Q G + P +P + + + VP PS S P Sbjct: 1393 MWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYM 1452 Query: 978 HSGAPPPPPSQPPRQPPQAAPSSHPHSDLTFNPSS 1012 S A P ++PP+ Q PS H +P+S Sbjct: 1453 SSSASMQPITRPPQPSYQTPPSLPNHISRAPSPAS 1487 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 65.9 bits (159), Expect = 2e-10 Identities = 85/344 (24%), Positives = 117/344 (34%), Gaps = 34/344 (9%) Query: 224 SAKAGPAQPYIQQSMYGRPNYPGSG----GFGASYPGGPNAPAGMGIPPHTRPPADFTQP 279 +A AGPA P + + P P +G G G GP +P +P PPA +P Sbjct: 70 AAGAGPAAP-AEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRP 128 Query: 280 ---AAAAAAAAVAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGP 336 +A + A V AAAA A A + + GP PGP Sbjct: 129 PPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPG--PGPGP 186 Query: 337 RGPASMGGSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQ 396 PA G + AA + + P + + P + P +P+ PG Q Sbjct: 187 GKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLP-------LPKPAAPGTVIQ 239 Query: 397 SLPIQNIKRP-YPGEPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQPS 455 + P P P P+ P + P P P P PP P T PG + Sbjct: 240 TPPFVGAAAPPAPAAPS------PPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTA 293 Query: 456 SGQYPPPTV-----NMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHS 510 + PPP + G P G SG G P P A P Sbjct: 294 APAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQP----GPGAAAAAPAPGVKAESPKR 349 Query: 511 PVPGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPPP 554 V P T +S P + S + P + P+ +A+PPP Sbjct: 350 VVQAAPPAAQTLAASGPASTAASMVIGPTMQGAL-PSPAAVPPP 392 Score = 52.0 bits (123), Expect = 3e-06 Identities = 52/214 (24%), Positives = 82/214 (38%), Gaps = 43/214 (20%) Query: 826 PIKSDLHIKDDPDGIPSKRFKTMSPSQMIMPNVMEMIAALGPGPSPYPLPPPPGGTNSND 885 P+ + + P+ P+ P++ P + A GPGP P P P P G + Sbjct: 139 PVPAAAAVAAGPEPAPA------GPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGP 192 Query: 886 YSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSH-PMQE 944 ++Q N +N P +S + P + L KP + + + Sbjct: 193 GAAQTLN-------------GSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQ 239 Query: 945 TMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSGAPPPPPSQP--------PRQPPQA 996 T P G++ P P+ P P + P + PPPPP+ P PP A Sbjct: 240 TPPFVGAAAPPAPA------APSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTA 293 Query: 997 APSSHPHSDLTFNPSSALEGQAGAQGASDMPEPS 1030 AP+ P P++A G G+ GA+ P P+ Sbjct: 294 APAVPP-------PAAAQNG--GSAGAAPAPAPA 318 Score = 46.6 bits (109), Expect = 1e-04 Identities = 62/243 (25%), Positives = 84/243 (34%), Gaps = 33/243 (13%) Query: 339 PASMGGSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSL 398 PA G+ PA+ A G + PP G +P G G R P GP P + Sbjct: 67 PAGAAGA-GPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVP-AGPAPPAA 124 Query: 399 PIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQPSSGQ 458 + RP P E + G+ P + G PAP P P R P G Sbjct: 125 KL----RP-PPEGSAGSCAPVPAAA-AVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGP 178 Query: 459 YPPPTVNMGQYYKP---EQFNGQNNTFSGSSYSNYSQGNVNRPPR---PVPVANYPHS-- 510 P P G+ P + NG + + + VN P P+P P + Sbjct: 179 GPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVI 238 Query: 511 -----------PVPGNPTPPMTPGSSIP------PYLSPSQDVKPPFPPDIKPNMSALPP 553 P P P+PP P + P P +P+ +PP P P + P Sbjct: 239 QTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVP 298 Query: 554 PPA 556 PPA Sbjct: 299 PPA 301 Score = 36.6 bits (83), Expect = 0.13 Identities = 62/262 (23%), Positives = 81/262 (30%), Gaps = 12/262 (4%) Query: 120 PGKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWGVTNTSQS 179 PG + PP ++ + S + P + P PP ++ + Sbjct: 234 PGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTA 293 Query: 180 QVLGNPMANANNPMNPGGNPM---ASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQ 236 P A A N + G P A+G G P A KA + +Q Sbjct: 294 APAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQA 353 Query: 237 SMYGRPNYPGSG--GFGASYPGGPNAPAGMGIPPHTRPPADFTQPA--AAAAAAAVAAAA 292 + SG AS GP + P PPA T AA A + + Sbjct: 354 APPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLS 413 Query: 293 ATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMGGS--MNPAS 350 T TAT + A L T P PT N F PG S G M P Sbjct: 414 RTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQN--FQLPPGMVLVRSENGQLLMIPQQ 471 Query: 351 MAAGMTPSGMSGPPMGMNQPRP 372 A M + P M PRP Sbjct: 472 ALAQMQAQAHAQPQTTM-APRP 492 Score = 32.0 bits (71), Expect = 3.2 Identities = 62/254 (24%), Positives = 75/254 (29%), Gaps = 37/254 (14%) Query: 225 AKAGPAQPYIQQSMYGRPNY---PGSGGFGASYPGGPNAPAGMGIPPHTRPPADFTQPAA 281 A AGPA+P ++ R PG G PG PAG G A + Sbjct: 153 APAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPG---KPAGPGAAQTLNGSAALLN-SH 208 Query: 282 AAAAAAVAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPAS 341 AAA AV+ A A T + G P P P PA+ Sbjct: 209 HAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAA 268 Query: 342 MGGSMNPASMAAGMTPSGMSGPPMGMNQPRPPGIS------------------PFGTHGQ 383 PA P +GPP PP + P G GQ Sbjct: 269 APPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQ 328 Query: 384 RMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGN--QQYGPNSQF------PTQPGQYPAP- 434 P P P + ++ KR P GP S PT G P+P Sbjct: 329 PGPGAAAAAPAP-GVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPA 387 Query: 435 --NPPRPLTSPNYP 446 PP P T P Sbjct: 388 AVPPPAPGTPTGLP 401 Score = 30.8 bits (68), Expect = 7.1 Identities = 31/120 (25%), Positives = 45/120 (37%), Gaps = 15/120 (12%) Query: 924 PPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHV---PHPSSQSGPPLHHSG 980 PP P A L +P HP P A + P + Q G P P+ +G P SG Sbjct: 270 PPPPPPAPATLARPPGHPAGP--PTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSG 327 Query: 981 APPPPPS----------QPPRQPPQAAPSSHPHSDLTFNPSSALEGQAGAQGASDMPEPS 1030 P P + + P++ QAAP + + S+A G +P P+ Sbjct: 328 QPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPA 387 >gi|55750053 atrophin-1 [Homo sapiens] Length = 1190 Score = 65.9 bits (159), Expect = 2e-10 Identities = 106/426 (24%), Positives = 158/426 (37%), Gaps = 83/426 (19%) Query: 124 PMQPPLSSMSSMKPTLSHSDGS-------FPYD-SVPWQQNTNQPPGSLSVVTTVWGVTN 175 PM+ P SS SS S S S FP ++P ++ PP SLSV T Sbjct: 370 PMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQ 429 Query: 176 TS-QSQVL-----------GNPMANANNPMNPGGNPMASG-MTTSNPGLNSPQFAGQQQQ 222 S SQ + G +AN+N +PG P ++G +T++P +++ QQQQ Sbjct: 430 PSLPSQAVWSQGPPPPPPYGRLLANSN--AHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQ 487 Query: 223 FSAKAGPAQPYIQQSMYGRPNYPGSGGF------GASYPGGPNA--PAGMGIPPHTRPPA 274 + Q QQ +G P G F G+S+ P A P+ + P+ PA Sbjct: 488 QQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPA 547 Query: 275 DFTQPAAAAAAAAVAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQP 334 P + + + ++++ ++ + Q Y P+ + Q P Sbjct: 548 HLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQ-------GSYPCSHPSPSQGPQGAPYP 600 Query: 335 GPRGPASMGGSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQ------Q 388 P P S +++ A + S P G PPG P+ G+R P Sbjct: 601 FPPVPTVTTSSATLSTVIATVASS-----PAGYKTASPPGPPPY---GKRAPSPGAYKTA 652 Query: 389 TYPGPRPQSLPIQNIKRPYPGEPNY--GNQQYGPNSQFPTQPGQYPAPNPPR-PLTSPNY 445 T PG +P S P P P Y + GP + P P P P PP P P+ Sbjct: 653 TPPGYKPGSPPSFRTGTP----PGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSL 708 Query: 446 PGQRMPSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVA 505 P P+ P+SG PP + + E++ P PVP A Sbjct: 709 PPP--PAAPASG--PPLSATQIKQEPAEEY--------------------ETPESPVPPA 744 Query: 506 NYPHSP 511 P P Sbjct: 745 RSPSPP 750 Score = 61.2 bits (147), Expect = 5e-09 Identities = 94/423 (22%), Positives = 141/423 (33%), Gaps = 72/423 (17%) Query: 161 PGSLSVVTTVWGVTNTSQSQVLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQ 220 P + T V G S P N P P P+ + + S PGL + G Sbjct: 271 PPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPL-NNASASPPGLGAQPLPGHL 329 Query: 221 QQFSAKAGPAQPYIQQSMYGRPNYPGSGGFGASYPGGPNAPAGMGIPPHTRPPADFTQPA 280 P+ G G G P GP + PH+ PPA + PA Sbjct: 330 PS-------------------PHAMGQGMGGL--PPGPEKGPTLAPSPHSLPPASSSAPA 368 Query: 281 --------AAAAAAAVAAAAATATATATATVAALQ---------------ETQNKDINQY 317 ++++++A A++++++++++ + A Q N+ Sbjct: 369 PPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYT 428 Query: 318 GPMGPTQAYNSQFMNQPGPRGPASMGGSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISP 377 P P+QA SQ P P G + +P G P G P +S Sbjct: 429 QPSLPSQAVWSQGPPPPPPYGRLLANSNAHP----------GPFPPSTGAQSTAHPPVST 478 Query: 378 FGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPP 437 H Q+ QQ Q ++ + ++GN P FP P + + + Sbjct: 479 HHHHHQQQQQQQQ----------QQQQQQQQQQQHHGNSGPPPPGAFP-HPLEGGSSHHA 527 Query: 438 RPLTSPNYPGQRMPSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNV-- 495 P G P P PPP + Y NG + S +S S+ SQG+ Sbjct: 528 HPYAMSPSLGSLRPYPPGPAHLPPPHSQVS--YSQAGPNGPPVSSSSNSSSSTSQGSYPC 585 Query: 496 --NRPPRPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPP 553 P + A YP PVP T T + I S K PP P P Sbjct: 586 SHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPS 645 Query: 554 PPA 556 P A Sbjct: 646 PGA 648 Score = 57.0 bits (136), Expect = 9e-08 Identities = 115/459 (25%), Positives = 142/459 (30%), Gaps = 100/459 (21%) Query: 119 PPGKLPMQPPLS--SMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWGVTNT 176 PP P QP S S+ PT H+ P S +Q PP + G Sbjct: 171 PPDSTPRQPEASFEPHPSVTPTGYHAPME-PPTSRMFQAPPGAPPPHPQLYPGGTG---- 225 Query: 177 SQSQVLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQ 236 VL P PM P G AS + N G P P P Sbjct: 226 ---GVLSGP------PMGPKGGGAASSVGGPNGGKQHPP-------------PTTPISVS 263 Query: 237 SMYGRPNYPGSGGFGASYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATAT 296 S SG GA P P G G P PPA+F P A Sbjct: 264 S---------SGASGAPPTKPPTTPVGGGNLPSAPPPANF--PHVTPNLPPPPALRPLNN 312 Query: 297 ATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMGGSMNPASMAAGMT 356 A+A+ Q P + M Q MGG + Sbjct: 313 ASASPPGLGAQPL------------PGHLPSPHAMGQ-------GMGGLPPGPEKGPTLA 353 Query: 357 PSGMSGPPMGMNQPRPPGISPF----------GTHGQRMPQQTYPGPRPQSLPIQNIKRP 406 PS S PP + P PP P+ + P P Q+LP P Sbjct: 354 PSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFP 413 Query: 407 YPGEPNYGNQQYGPNSQFPTQPGQY-----PAPNPP--RPLTSPN-YPGQRMPSQPSSGQ 458 P + NQ P P+ P Q P P PP R L + N +PG PS + Sbjct: 414 PPTSLSVSNQP--PKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQST 471 Query: 459 YPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHSPVPGNPTP 518 PP V+ ++ +Q Q GN PP PG Sbjct: 472 AHPP-VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP-------------PGAFPH 517 Query: 519 PMTPGSS--IPPY-LSPSQDVKPPFPPDIKPNMSALPPP 554 P+ GSS PY +SPS P+P P + LPPP Sbjct: 518 PLEGGSSHHAHPYAMSPSLGSLRPYP----PGPAHLPPP 552 Score = 53.1 bits (126), Expect = 1e-06 Identities = 86/413 (20%), Positives = 135/413 (32%), Gaps = 75/413 (18%) Query: 192 PMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQSMYGRPNYPGSGGFG 251 P +P G + ++ G + P+ Q + ++ S+Y + Sbjct: 99 PQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSP----------SIYSPGSVENDSDSS 148 Query: 252 ASYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATATATATATVAALQETQN 311 + GP P PP PP+ QP + A+ + T T A ++ + Sbjct: 149 SGLSQGPARPYH---PPPLFPPSP--QPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTS 203 Query: 312 KDIN----------QYGPMGPTQAYNSQFMNQPGPRGPASMGGSMN-----PASMAAGMT 356 + Q P G + M G +S+GG P + ++ Sbjct: 204 RMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVS 263 Query: 357 PSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQ 416 SG SG P P P +P G G +P P P P N+ P P Sbjct: 264 SSGASGAP-----PTKPPTTPVG--GGNLPSAPPPANFPHVTP--NLPPPPALRPLNNAS 314 Query: 417 QYGPNSQFPTQPGQYPAPN---------PPRPLTSPNYPGQRMPSQPSSGQYPPPTVNMG 467 P PG P+P+ PP P P P+S P P + Sbjct: 315 ASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRF- 373 Query: 468 QYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHSPVPGNP----------T 517 + +++ + SS S+ S + + P + +YPHS P T Sbjct: 374 -----PYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYT 428 Query: 518 PPMTPGSSI--------PPY---LSPSQDVKPPFPPDIKPNMSALPPPPANHN 559 P P ++ PPY L+ S PFPP +A PP +H+ Sbjct: 429 QPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHH 481 Score = 41.2 bits (95), Expect = 0.005 Identities = 38/132 (28%), Positives = 50/132 (37%), Gaps = 13/132 (9%) Query: 906 PGGTSMNDFMHGPPQLSHPPDMP--NNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGL 963 P +F H P L PP + NN +A S P P G PH ++ QG+ Sbjct: 286 PSAPPPANFPHVTPNLPPPPALRPLNNASA-----SPPGLGAQPLPGHLPSPH-AMGQGM 339 Query: 964 HVPHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEGQAGAQGA 1023 P + GP L S PP S PP P S S S+A + + + Sbjct: 340 GGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSS-----SAAASSSSSSSSS 394 Query: 1024 SDMPEPSLDLLP 1035 S P P+ LP Sbjct: 395 SASPFPASQALP 406 Score = 38.1 bits (87), Expect = 0.045 Identities = 42/177 (23%), Positives = 59/177 (33%), Gaps = 25/177 (14%) Query: 869 PSPYPLPPP-------PGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQL 921 P P LPPP G N SS N+ +P +P + GP Sbjct: 544 PGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQ------GPQGA 597 Query: 922 SHP----PDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLH 977 +P P + + A L ++ + +S P + P + PP + Sbjct: 598 PYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGY 657 Query: 978 HSGAPPPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEG-----QAGAQGASDMPEP 1029 G+PP S PP +S P TF P S G AG G +P P Sbjct: 658 KPGSPP---SFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPP 711 Score = 37.7 bits (86), Expect = 0.058 Identities = 66/272 (24%), Positives = 91/272 (33%), Gaps = 40/272 (14%) Query: 321 GPTQAYNSQFMNQPGPRGPASMGGSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISPFGT 380 GP + S+ PG +S G + A + P Q R IS + Sbjct: 22 GPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESES 81 Query: 381 HGQRMPQQTYPG---PRPQS------LPIQNIKRPYPGEPNYGNQQYGPNSQFPTQPG-- 429 P++T PRPQS L +++ +P +Q S PG Sbjct: 82 EETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSV 141 Query: 430 -----------QYPA-PNPPRPLTSPN-YPGQRMPSQPSSGQYPPPTVNMGQYYKPEQFN 476 Q PA P P PL P+ P P QP + P P+V Y+ P + Sbjct: 142 ENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPME-P 200 Query: 477 GQNNTFSGSS---------YSNYSQGNVNRPPRPVPVANYPHSPVPG-----NPTPPMTP 522 + F Y + G ++ PP P S V G PP TP Sbjct: 201 PTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMG-PKGGGAASSVGGPNGGKQHPPPTTP 259 Query: 523 GSSIPPYLSPSQDVKPPFPPDIKPNMSALPPP 554 S S + KPP P N+ + PPP Sbjct: 260 ISVSSSGASGAPPTKPPTTPVGGGNLPSAPPP 291 Score = 37.4 bits (85), Expect = 0.076 Identities = 38/126 (30%), Positives = 49/126 (38%), Gaps = 10/126 (7%) Query: 870 SPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPPDMPN 929 SP L G + ++D SS + P G+ ND LS P P Sbjct: 101 SPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVEND-SDSSSGLSQGPARPY 159 Query: 930 NMAALEKPLSHPMQETMPHAGSSDQPHPSI-QQGLHVP--HPSSQ--SGPPLHHSGAPPP 984 + L P P T +S +PHPS+ G H P P+S+ PP GAPPP Sbjct: 160 HPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPP----GAPPP 215 Query: 985 PPSQPP 990 P P Sbjct: 216 HPQLYP 221 Score = 37.0 bits (84), Expect = 0.099 Identities = 48/206 (23%), Positives = 69/206 (33%), Gaps = 55/206 (26%) Query: 850 PSQMIMPNVM-EMIAALGPGP--------SPYPLPP-------PP--------------G 879 P + P+ M + + L PGP SP+ LPP PP Sbjct: 326 PGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAA 385 Query: 880 GTNSNDYSSQGNNYQGHGNF-DFPHGNPGGTSMNDFMHGPPQLSHP------------PD 926 ++S+ SS + + +PH P TS++ + PP+ + P P Sbjct: 386 SSSSSSSSSSASPFPASQALPSYPHSFPPPTSLS-VSNQPPKYTQPSLPSQAVWSQGPPP 444 Query: 927 MPNNMAALEKPLSHPMQETMPHAGSSDQPHPSI---------QQGLHVPHPSSQSGPPLH 977 P L +HP P G+ HP + QQ Q H Sbjct: 445 PPPYGRLLANSNAHP-GPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQH 503 Query: 978 HSGAPPPPPSQPPRQPPQAAPSSHPH 1003 H + PPPP P P + S H H Sbjct: 504 HGNSGPPPPGAFP-HPLEGGSSHHAH 528 Score = 34.7 bits (78), Expect = 0.49 Identities = 39/139 (28%), Positives = 47/139 (33%), Gaps = 15/139 (10%) Query: 866 GPGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPP 925 GP +PYP PP P T S+ S + +P G PP P Sbjct: 593 GPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGP--------PPYGKRAP 644 Query: 926 DMPNNMAALE---KPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSG--PPLHHSG 980 A KP S P T G P+ P+ G PP SG Sbjct: 645 SPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG 704 Query: 981 AP--PPPPSQPPRQPPQAA 997 P PPPP+ P PP +A Sbjct: 705 LPSLPPPPAAPASGPPLSA 723 Score = 32.7 bits (73), Expect = 1.9 Identities = 39/170 (22%), Positives = 52/170 (30%), Gaps = 34/170 (20%) Query: 873 PLPPPPGG---TNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPPDMPN 929 P PPPP G NSN + P P T H P H Sbjct: 442 PPPPPPYGRLLANSNAH---------------PGPFPPSTGAQSTAHPPVSTHHHHHQQQ 486 Query: 930 NMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSGAPPPPPSQP 989 ++ Q+ H G+S P P PHP H A P Sbjct: 487 QQQQQQQ--QQQQQQQQQHHGNSGPPPPGA-----FPHPLEGGSSHHAHPYAMSPSLGSL 539 Query: 990 PRQPPQAAPSSHPHSDLTFN---------PSSALEGQAGAQGASDMPEPS 1030 PP A PHS ++++ SS+ + +QG+ PS Sbjct: 540 RPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPS 589 Score = 31.6 bits (70), Expect = 4.2 Identities = 41/189 (21%), Positives = 56/189 (29%), Gaps = 37/189 (19%) Query: 878 PGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKP 937 PG ++ SS G + + P P D P+ S P P Sbjct: 138 PGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAP 197 Query: 938 LSHPMQETMPHAGSSDQPHPSIQQG---------------------LHVPHPSSQSGPP- 975 + P + PHP + G + P+ Q PP Sbjct: 198 MEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPT 257 Query: 976 ----LHHSGAPPPPPSQPPRQP------PQA-APSSHPHSDLTFNPSSAL----EGQAGA 1020 + SGA PP++PP P P A P++ PH P AL A Sbjct: 258 TPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP 317 Query: 1021 QGASDMPEP 1029 G P P Sbjct: 318 PGLGAQPLP 326 >gi|55750041 atrophin-1 [Homo sapiens] Length = 1190 Score = 65.9 bits (159), Expect = 2e-10 Identities = 106/426 (24%), Positives = 158/426 (37%), Gaps = 83/426 (19%) Query: 124 PMQPPLSSMSSMKPTLSHSDGS-------FPYD-SVPWQQNTNQPPGSLSVVTTVWGVTN 175 PM+ P SS SS S S S FP ++P ++ PP SLSV T Sbjct: 370 PMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQ 429 Query: 176 TS-QSQVL-----------GNPMANANNPMNPGGNPMASG-MTTSNPGLNSPQFAGQQQQ 222 S SQ + G +AN+N +PG P ++G +T++P +++ QQQQ Sbjct: 430 PSLPSQAVWSQGPPPPPPYGRLLANSN--AHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQ 487 Query: 223 FSAKAGPAQPYIQQSMYGRPNYPGSGGF------GASYPGGPNA--PAGMGIPPHTRPPA 274 + Q QQ +G P G F G+S+ P A P+ + P+ PA Sbjct: 488 QQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPA 547 Query: 275 DFTQPAAAAAAAAVAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQP 334 P + + + ++++ ++ + Q Y P+ + Q P Sbjct: 548 HLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQ-------GSYPCSHPSPSQGPQGAPYP 600 Query: 335 GPRGPASMGGSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQ------Q 388 P P S +++ A + S P G PPG P+ G+R P Sbjct: 601 FPPVPTVTTSSATLSTVIATVASS-----PAGYKTASPPGPPPY---GKRAPSPGAYKTA 652 Query: 389 TYPGPRPQSLPIQNIKRPYPGEPNY--GNQQYGPNSQFPTQPGQYPAPNPPR-PLTSPNY 445 T PG +P S P P P Y + GP + P P P P PP P P+ Sbjct: 653 TPPGYKPGSPPSFRTGTP----PGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSL 708 Query: 446 PGQRMPSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVA 505 P P+ P+SG PP + + E++ P PVP A Sbjct: 709 PPP--PAAPASG--PPLSATQIKQEPAEEY--------------------ETPESPVPPA 744 Query: 506 NYPHSP 511 P P Sbjct: 745 RSPSPP 750 Score = 61.2 bits (147), Expect = 5e-09 Identities = 94/423 (22%), Positives = 141/423 (33%), Gaps = 72/423 (17%) Query: 161 PGSLSVVTTVWGVTNTSQSQVLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQ 220 P + T V G S P N P P P+ + + S PGL + G Sbjct: 271 PPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPL-NNASASPPGLGAQPLPGHL 329 Query: 221 QQFSAKAGPAQPYIQQSMYGRPNYPGSGGFGASYPGGPNAPAGMGIPPHTRPPADFTQPA 280 P+ G G G P GP + PH+ PPA + PA Sbjct: 330 PS-------------------PHAMGQGMGGL--PPGPEKGPTLAPSPHSLPPASSSAPA 368 Query: 281 --------AAAAAAAVAAAAATATATATATVAALQ---------------ETQNKDINQY 317 ++++++A A++++++++++ + A Q N+ Sbjct: 369 PPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYT 428 Query: 318 GPMGPTQAYNSQFMNQPGPRGPASMGGSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISP 377 P P+QA SQ P P G + +P G P G P +S Sbjct: 429 QPSLPSQAVWSQGPPPPPPYGRLLANSNAHP----------GPFPPSTGAQSTAHPPVST 478 Query: 378 FGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPP 437 H Q+ QQ Q ++ + ++GN P FP P + + + Sbjct: 479 HHHHHQQQQQQQQ----------QQQQQQQQQQQHHGNSGPPPPGAFP-HPLEGGSSHHA 527 Query: 438 RPLTSPNYPGQRMPSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNV-- 495 P G P P PPP + Y NG + S +S S+ SQG+ Sbjct: 528 HPYAMSPSLGSLRPYPPGPAHLPPPHSQVS--YSQAGPNGPPVSSSSNSSSSTSQGSYPC 585 Query: 496 --NRPPRPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPP 553 P + A YP PVP T T + I S K PP P P Sbjct: 586 SHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPS 645 Query: 554 PPA 556 P A Sbjct: 646 PGA 648 Score = 57.0 bits (136), Expect = 9e-08 Identities = 115/459 (25%), Positives = 142/459 (30%), Gaps = 100/459 (21%) Query: 119 PPGKLPMQPPLS--SMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWGVTNT 176 PP P QP S S+ PT H+ P S +Q PP + G Sbjct: 171 PPDSTPRQPEASFEPHPSVTPTGYHAPME-PPTSRMFQAPPGAPPPHPQLYPGGTG---- 225 Query: 177 SQSQVLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQ 236 VL P PM P G AS + N G P P P Sbjct: 226 ---GVLSGP------PMGPKGGGAASSVGGPNGGKQHPP-------------PTTPISVS 263 Query: 237 SMYGRPNYPGSGGFGASYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATAT 296 S SG GA P P G G P PPA+F P A Sbjct: 264 S---------SGASGAPPTKPPTTPVGGGNLPSAPPPANF--PHVTPNLPPPPALRPLNN 312 Query: 297 ATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMGGSMNPASMAAGMT 356 A+A+ Q P + M Q MGG + Sbjct: 313 ASASPPGLGAQPL------------PGHLPSPHAMGQ-------GMGGLPPGPEKGPTLA 353 Query: 357 PSGMSGPPMGMNQPRPPGISPF----------GTHGQRMPQQTYPGPRPQSLPIQNIKRP 406 PS S PP + P PP P+ + P P Q+LP P Sbjct: 354 PSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFP 413 Query: 407 YPGEPNYGNQQYGPNSQFPTQPGQY-----PAPNPP--RPLTSPN-YPGQRMPSQPSSGQ 458 P + NQ P P+ P Q P P PP R L + N +PG PS + Sbjct: 414 PPTSLSVSNQP--PKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQST 471 Query: 459 YPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHSPVPGNPTP 518 PP V+ ++ +Q Q GN PP PG Sbjct: 472 AHPP-VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP-------------PGAFPH 517 Query: 519 PMTPGSS--IPPY-LSPSQDVKPPFPPDIKPNMSALPPP 554 P+ GSS PY +SPS P+P P + LPPP Sbjct: 518 PLEGGSSHHAHPYAMSPSLGSLRPYP----PGPAHLPPP 552 Score = 53.1 bits (126), Expect = 1e-06 Identities = 86/413 (20%), Positives = 135/413 (32%), Gaps = 75/413 (18%) Query: 192 PMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQPYIQQSMYGRPNYPGSGGFG 251 P +P G + ++ G + P+ Q + ++ S+Y + Sbjct: 99 PQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSP----------SIYSPGSVENDSDSS 148 Query: 252 ASYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATATATATATVAALQETQN 311 + GP P PP PP+ QP + A+ + T T A ++ + Sbjct: 149 SGLSQGPARPYH---PPPLFPPSP--QPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTS 203 Query: 312 KDIN----------QYGPMGPTQAYNSQFMNQPGPRGPASMGGSMN-----PASMAAGMT 356 + Q P G + M G +S+GG P + ++ Sbjct: 204 RMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVS 263 Query: 357 PSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQ 416 SG SG P P P +P G G +P P P P N+ P P Sbjct: 264 SSGASGAP-----PTKPPTTPVG--GGNLPSAPPPANFPHVTP--NLPPPPALRPLNNAS 314 Query: 417 QYGPNSQFPTQPGQYPAPN---------PPRPLTSPNYPGQRMPSQPSSGQYPPPTVNMG 467 P PG P+P+ PP P P P+S P P + Sbjct: 315 ASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRF- 373 Query: 468 QYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHSPVPGNP----------T 517 + +++ + SS S+ S + + P + +YPHS P T Sbjct: 374 -----PYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYT 428 Query: 518 PPMTPGSSI--------PPY---LSPSQDVKPPFPPDIKPNMSALPPPPANHN 559 P P ++ PPY L+ S PFPP +A PP +H+ Sbjct: 429 QPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHH 481 Score = 41.2 bits (95), Expect = 0.005 Identities = 38/132 (28%), Positives = 50/132 (37%), Gaps = 13/132 (9%) Query: 906 PGGTSMNDFMHGPPQLSHPPDMP--NNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGL 963 P +F H P L PP + NN +A S P P G PH ++ QG+ Sbjct: 286 PSAPPPANFPHVTPNLPPPPALRPLNNASA-----SPPGLGAQPLPGHLPSPH-AMGQGM 339 Query: 964 HVPHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEGQAGAQGA 1023 P + GP L S PP S PP P S S S+A + + + Sbjct: 340 GGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSS-----SAAASSSSSSSSS 394 Query: 1024 SDMPEPSLDLLP 1035 S P P+ LP Sbjct: 395 SASPFPASQALP 406 Score = 38.1 bits (87), Expect = 0.045 Identities = 42/177 (23%), Positives = 59/177 (33%), Gaps = 25/177 (14%) Query: 869 PSPYPLPPP-------PGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQL 921 P P LPPP G N SS N+ +P +P + GP Sbjct: 544 PGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQ------GPQGA 597 Query: 922 SHP----PDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLH 977 +P P + + A L ++ + +S P + P + PP + Sbjct: 598 PYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGY 657 Query: 978 HSGAPPPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEG-----QAGAQGASDMPEP 1029 G+PP S PP +S P TF P S G AG G +P P Sbjct: 658 KPGSPP---SFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPP 711 Score = 37.7 bits (86), Expect = 0.058 Identities = 66/272 (24%), Positives = 91/272 (33%), Gaps = 40/272 (14%) Query: 321 GPTQAYNSQFMNQPGPRGPASMGGSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISPFGT 380 GP + S+ PG +S G + A + P Q R IS + Sbjct: 22 GPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESES 81 Query: 381 HGQRMPQQTYPG---PRPQS------LPIQNIKRPYPGEPNYGNQQYGPNSQFPTQPG-- 429 P++T PRPQS L +++ +P +Q S PG Sbjct: 82 EETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSV 141 Query: 430 -----------QYPA-PNPPRPLTSPN-YPGQRMPSQPSSGQYPPPTVNMGQYYKPEQFN 476 Q PA P P PL P+ P P QP + P P+V Y+ P + Sbjct: 142 ENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPME-P 200 Query: 477 GQNNTFSGSS---------YSNYSQGNVNRPPRPVPVANYPHSPVPG-----NPTPPMTP 522 + F Y + G ++ PP P S V G PP TP Sbjct: 201 PTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMG-PKGGGAASSVGGPNGGKQHPPPTTP 259 Query: 523 GSSIPPYLSPSQDVKPPFPPDIKPNMSALPPP 554 S S + KPP P N+ + PPP Sbjct: 260 ISVSSSGASGAPPTKPPTTPVGGGNLPSAPPP 291 Score = 37.4 bits (85), Expect = 0.076 Identities = 38/126 (30%), Positives = 49/126 (38%), Gaps = 10/126 (7%) Query: 870 SPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPPDMPN 929 SP L G + ++D SS + P G+ ND LS P P Sbjct: 101 SPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVEND-SDSSSGLSQGPARPY 159 Query: 930 NMAALEKPLSHPMQETMPHAGSSDQPHPSI-QQGLHVP--HPSSQ--SGPPLHHSGAPPP 984 + L P P T +S +PHPS+ G H P P+S+ PP GAPPP Sbjct: 160 HPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPP----GAPPP 215 Query: 985 PPSQPP 990 P P Sbjct: 216 HPQLYP 221 Score = 37.0 bits (84), Expect = 0.099 Identities = 48/206 (23%), Positives = 69/206 (33%), Gaps = 55/206 (26%) Query: 850 PSQMIMPNVM-EMIAALGPGP--------SPYPLPP-------PP--------------G 879 P + P+ M + + L PGP SP+ LPP PP Sbjct: 326 PGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAA 385 Query: 880 GTNSNDYSSQGNNYQGHGNF-DFPHGNPGGTSMNDFMHGPPQLSHP------------PD 926 ++S+ SS + + +PH P TS++ + PP+ + P P Sbjct: 386 SSSSSSSSSSASPFPASQALPSYPHSFPPPTSLS-VSNQPPKYTQPSLPSQAVWSQGPPP 444 Query: 927 MPNNMAALEKPLSHPMQETMPHAGSSDQPHPSI---------QQGLHVPHPSSQSGPPLH 977 P L +HP P G+ HP + QQ Q H Sbjct: 445 PPPYGRLLANSNAHP-GPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQH 503 Query: 978 HSGAPPPPPSQPPRQPPQAAPSSHPH 1003 H + PPPP P P + S H H Sbjct: 504 HGNSGPPPPGAFP-HPLEGGSSHHAH 528 Score = 34.7 bits (78), Expect = 0.49 Identities = 39/139 (28%), Positives = 47/139 (33%), Gaps = 15/139 (10%) Query: 866 GPGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPP 925 GP +PYP PP P T S+ S + +P G PP P Sbjct: 593 GPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGP--------PPYGKRAP 644 Query: 926 DMPNNMAALE---KPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSG--PPLHHSG 980 A KP S P T G P+ P+ G PP SG Sbjct: 645 SPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG 704 Query: 981 AP--PPPPSQPPRQPPQAA 997 P PPPP+ P PP +A Sbjct: 705 LPSLPPPPAAPASGPPLSA 723 Score = 32.7 bits (73), Expect = 1.9 Identities = 39/170 (22%), Positives = 52/170 (30%), Gaps = 34/170 (20%) Query: 873 PLPPPPGG---TNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPPDMPN 929 P PPPP G NSN + P P T H P H Sbjct: 442 PPPPPPYGRLLANSNAH---------------PGPFPPSTGAQSTAHPPVSTHHHHHQQQ 486 Query: 930 NMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSGAPPPPPSQP 989 ++ Q+ H G+S P P PHP H A P Sbjct: 487 QQQQQQQ--QQQQQQQQQHHGNSGPPPPGA-----FPHPLEGGSSHHAHPYAMSPSLGSL 539 Query: 990 PRQPPQAAPSSHPHSDLTFN---------PSSALEGQAGAQGASDMPEPS 1030 PP A PHS ++++ SS+ + +QG+ PS Sbjct: 540 RPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPS 589 Score = 31.6 bits (70), Expect = 4.2 Identities = 41/189 (21%), Positives = 56/189 (29%), Gaps = 37/189 (19%) Query: 878 PGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKP 937 PG ++ SS G + + P P D P+ S P P Sbjct: 138 PGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAP 197 Query: 938 LSHPMQETMPHAGSSDQPHPSIQQG---------------------LHVPHPSSQSGPP- 975 + P + PHP + G + P+ Q PP Sbjct: 198 MEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPT 257 Query: 976 ----LHHSGAPPPPPSQPPRQP------PQA-APSSHPHSDLTFNPSSAL----EGQAGA 1020 + SGA PP++PP P P A P++ PH P AL A Sbjct: 258 TPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP 317 Query: 1021 QGASDMPEP 1029 G P P Sbjct: 318 PGLGAQPLP 326 >gi|42544123 splicing factor 1 isoform 3 [Homo sapiens] Length = 548 Score = 65.9 bits (159), Expect = 2e-10 Identities = 62/224 (27%), Positives = 83/224 (37%), Gaps = 32/224 (14%) Query: 339 PASMGGSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSL 398 PAS+G + PA+ P P N P PP + + Q P GP +S Sbjct: 326 PASVGSTSGPATTPLASAPR----PAAPANNPPPPSLM---STTQSRPPWMNSGPS-ESR 377 Query: 399 PIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQPSSG- 457 P + PG P G P +P P P +P Q P+ P Sbjct: 378 PYHGMHGGGPGGPGGG-------------PHSFPHPLPSLTGGHGGHPMQHNPNGPPPPW 424 Query: 458 -QYPPPTVNMG-----QYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHSP 511 Q PPP +N G + P +T GS QG PP P+ + P P Sbjct: 425 MQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPP 484 Query: 512 VPGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPPPP 555 G P PP P +PP+ Q +PP PP +M++ P P Sbjct: 485 PSGQPPPP--PSGPLPPW--QQQQQQPPPPPPPSSSMASSTPLP 524 Score = 43.5 bits (101), Expect = 0.001 Identities = 51/178 (28%), Positives = 59/178 (33%), Gaps = 45/178 (25%) Query: 864 ALGPGPS-PYPLPPPP---------------GGTNSNDYSSQ---GNNYQGHGNFDFPH- 903 A P P+ P PPPP G + S Y G G G FPH Sbjct: 341 ASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHP 400 Query: 904 -----GNPGGTSMNDFMHGPPQ-LSHPPDMPNNMAALEKPLSH----PMQETMP------ 947 G GG M +GPP PP P N P H PM + + Sbjct: 401 LPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGP--HPPGHHGPPPMDQYLGSTPVGS 458 Query: 948 -----HAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSS 1000 H G P P + G+ P P SG P P PP Q +QPP P S Sbjct: 459 GVYRLHQGKGMMPPPPM--GMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPS 514 Score = 38.9 bits (89), Expect = 0.026 Identities = 51/207 (24%), Positives = 71/207 (34%), Gaps = 26/207 (12%) Query: 273 PADFTQPAAAAAAAAVAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMN 332 PA + A +A A A + + TQ++ + GP+++ M+ Sbjct: 326 PASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRP--PWMNSGPSESRPYHGMH 383 Query: 333 QPGPRGPASMGGSM-NPA-SMAAGMTPSGM----SGPPMGMNQPRPP----GISPFGTHG 382 GP GP S +P S+ G M +GPP QP PP G P G HG Sbjct: 384 GGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHG 443 Query: 383 QRMPQQTYPGPRPQSLPIQNIKR-------------PYPGEPNYGNQQYGPNSQFPTQPG 429 P Y G P + + + P P P G P+ P Sbjct: 444 PP-PMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQ 502 Query: 430 QYPAPNPPRPLTSPNYPGQRMPSQPSS 456 Q P PP P +S +P Q S Sbjct: 503 QQQQPPPPPPPSSSMASSTPLPWQQRS 529 Score = 38.5 bits (88), Expect = 0.034 Identities = 42/151 (27%), Positives = 58/151 (38%), Gaps = 31/151 (20%) Query: 428 PGQYPAPNPPRPLTSPNYPGQRMPSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSY 487 P P + PRP N P PS S+ Q PP +N G + ++G + G Sbjct: 335 PATTPLASAPRPAAPANNPPP--PSLMSTTQSRPPWMNSGPS-ESRPYHGMHGGGPGGP- 390 Query: 488 SNYSQGNVNRPPRPVPVANYPHS--PVPGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDIK 545 G + P P+P H P+ NP P PP++ P PP Sbjct: 391 ----GGGPHSFPHPLPSLTGGHGGHPMQHNPNGPP------PPWMQP--------PP--- 429 Query: 546 PNMSALPPPPANHN----DELRLTFPVRDGV 572 P M+ P PP +H D+ + PV GV Sbjct: 430 PPMNQGPHPPGHHGPPPMDQYLGSTPVGSGV 460 Score = 36.2 bits (82), Expect = 0.17 Identities = 35/137 (25%), Positives = 41/137 (29%), Gaps = 11/137 (8%) Query: 866 GPGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPP 925 GP P+PLP GG + N P P MN H PP PP Sbjct: 393 GPHSFPHPLPSLTGGHGGHPMQHNPNGPPP------PWMQPPPPPMNQGPH-PPGHHGPP 445 Query: 926 DMPNNMAALEKPLS----HPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSGA 981 M + + H + MP P P P P S PP Sbjct: 446 PMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQ 505 Query: 982 PPPPPSQPPRQPPQAAP 998 PPPP P + P Sbjct: 506 QPPPPPPPSSSMASSTP 522 Score = 35.8 bits (81), Expect = 0.22 Identities = 34/117 (29%), Positives = 38/117 (32%), Gaps = 21/117 (17%) Query: 947 PHAGSSDQPHPSIQ-QGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSHPHSD 1005 P G PHP G H HP H+ PPPP QPP PP HP Sbjct: 390 PGGGPHSFPHPLPSLTGGHGGHPMQ------HNPNGPPPPWMQPP--PPPMNQGPHPPGH 441 Query: 1006 LTFNPSSALEGQAGA--------QGASDMPEPSLDLLPELTNPDELLSYLDPPDLPS 1054 P G QG MP P + ++P P PP PS Sbjct: 442 HGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPS----GQPPPPPS 494 >gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] Length = 680 Score = 64.3 bits (155), Expect = 6e-10 Identities = 107/444 (24%), Positives = 139/444 (31%), Gaps = 118/444 (26%) Query: 192 PMNPGGNPMASGMTT-SNPGLNSPQFAGQQQQFSAKAG-PAQPYIQ----QSMYGRPNYP 245 P P G P +G++ PG P A + F + G P P + + YG P P Sbjct: 140 PPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRP 199 Query: 246 GSGGF-GASYPGGPNAPAGMGI--------------------------------PPHTRP 272 G G G P GP+ P G+G PP R Sbjct: 200 GERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERG 259 Query: 273 PADFTQPAAAAAAAAVAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMN 332 P +P AA A A GP GP Sbjct: 260 PEGIGKPGAAGAPGQPGIPGTKGLPGAPGIA--------------GPPGPPGFGKPGLPG 305 Query: 333 QPGPRGPASMGGS------MNPASMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMP 386 G RGPA + G PA + G++GPP M P GI G+HG P Sbjct: 306 LKGERGPAGLPGGPGAKGEQGPAGLPG---KPGLTGPPGNMGPQGPKGIP--GSHGLPGP 360 Query: 387 QQT--------YPGPRPQ-SLPIQNIKRPYPGEPNYGNQQYGPNSQFPTQP----GQYPA 433 + YPG + + P + K YPG+P + P P G Sbjct: 361 KGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGL 420 Query: 434 PNPPRPLTSPNYPGQRMPSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQG 493 P P P + PG + P P T P G F GS S G Sbjct: 421 PGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGP---IGPPGIPG----FPGSKGDPGSPG 473 Query: 494 NVNRPPRPVPVA----NYPHSP--------------VPGNPTPPMTPGSSIPP--YLSPS 533 PP P +A N P P +PG P PP PG ++ P ++ Sbjct: 474 ----PPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAG 529 Query: 534 QDVKPPFPPDIKPNMSALPPPPAN 557 Q +P++S P AN Sbjct: 530 Q----------RPSLSGTPLVSAN 543 Score = 51.2 bits (121), Expect = 5e-06 Identities = 75/281 (26%), Positives = 94/281 (33%), Gaps = 54/281 (19%) Query: 318 GPMGPT--QAYNSQFMNQ----PGPRGPASMG-----------GSMNPASMAAGMTPSGM 360 GP GP Y S + PGP GP+++G G P + P+G+ Sbjct: 75 GPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGL 134 Query: 361 ---SGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPR-------PQSLPIQNIKRPYPGE 410 GPP P P GIS G GQ+ P PGPR +P N ++ GE Sbjct: 135 PGPRGPPGPPGIPGPAGISVPGKPGQQGPTGA-PGPRGFPGEKGAPGVPGMNGQK---GE 190 Query: 411 PNYG-----NQQYGPNSQFPTQP---------GQYPAPNPPRPLTSPNYPGQRMPSQPSS 456 YG ++ P Q PT P G+ P P +PG+ P P Sbjct: 191 MGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPG 250 Query: 457 GQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHSPVPGNP 516 Q PP KP +G+ G P P +A P P G P Sbjct: 251 PQGPPGERGPEGIGKPGA--------AGAPGQPGIPGTKGLPGAP-GIAGPPGPPGFGKP 301 Query: 517 TPPMTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPPPPAN 557 P G P L K P P L PP N Sbjct: 302 GLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGN 342 Score = 42.0 bits (97), Expect = 0.003 Identities = 59/227 (25%), Positives = 77/227 (33%), Gaps = 39/227 (17%) Query: 837 PDGIPSKRFKTMSPSQMIMPNVMEMIAALG-PGPSPYPLPPPPGGTNS--NDYSSQGNN- 892 P G+P K T P M + + G PGP P P G + S G++ Sbjct: 327 PAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDG 386 Query: 893 ---YQGHGNFDFPHGNPG--GTSMNDFMHGPPQLSHP---------------------PD 926 Y G D P GNPG G + + GPP L P P Sbjct: 387 KPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPG 446 Query: 927 MPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGP--PLHHSGAPP- 983 +P + P + GS P P+ + P+ GP P HSG P Sbjct: 447 IPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGL 506 Query: 984 PPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEGQ---AGAQGASDMP 1027 P P PP P QA P + +L G + QG + MP Sbjct: 507 PGPPGPPGPPGQAV---MPEGFIKAGQRPSLSGTPLVSANQGVTGMP 550 Score = 38.9 bits (89), Expect = 0.026 Identities = 66/256 (25%), Positives = 88/256 (34%), Gaps = 49/256 (19%) Query: 334 PGPRGPASMGGSMNPASM-------AAGMT-PSGMSGP--PMGMNQPRPPGI-------S 376 PGP GPA G P+ + G+ G+ GP P + +P PG+ Sbjct: 62 PGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERG 121 Query: 377 PFGTHGQRMPQQTYPGPRPQSLPIQNIKRP----YPGEPNYGNQQYGPNSQFPTQ--PGQ 430 P+G G P PGPR P I P PG+P Q GP + PG+ Sbjct: 122 PYGPKGDVGP-AGLPGPRGPPGP-PGIPGPAGISVPGKPG----QQGPTGAPGPRGFPGE 175 Query: 431 YPAPNPP--------RPLTSPNYPGQR---MPSQPSSGQYPPPTVNMGQYYKPEQFNGQN 479 AP P +P PG+R P P+ PP G+ P Q + Sbjct: 176 KGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKG 235 Query: 480 NTFSGSSYSNYSQGNVNRPP---RPVPVANYPHSPVPGNPTPPMTPGSSIPPYLSPSQDV 536 + PP P + + PG P P T G P ++ Sbjct: 236 DRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIA----- 290 Query: 537 KPPFPPDI-KPNMSAL 551 PP PP KP + L Sbjct: 291 GPPGPPGFGKPGLPGL 306 Score = 33.5 bits (75), Expect = 1.1 Identities = 45/180 (25%), Positives = 58/180 (32%), Gaps = 39/180 (21%) Query: 851 SQMIMPNVMEMIAALGPGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTS 910 +Q +P ++ G P PP P G +GH P G PG S Sbjct: 40 TQFFIPYTIKSKGIAVRGEQGTPGPPGPAGP------------RGHPGPSGPPGKPGYGS 87 Query: 911 MNDFMHGPPQLSHPPDMPNNMAALEKP----LSHPMQETMPHAGSSDQPHPSIQQGLHVP 966 + G P L PP +A+ KP L E P+ D + P Sbjct: 88 PG--LQGEPGLPGPP----GPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGL------P 135 Query: 967 HPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEGQAGAQGASDM 1026 P GPP G P P P +P Q P+ P G+ GA G M Sbjct: 136 GPRGPPGPP----GIPGPAGISVPGKPGQQGPTGAP-------GPRGFPGEKGAPGVPGM 184 Score = 30.4 bits (67), Expect = 9.3 Identities = 19/73 (26%), Positives = 26/73 (35%) Query: 955 PHPSIQQGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSHPHSDLTFNPSSAL 1014 P+ +G+ V GPP P PS PP +P +P L P + Sbjct: 45 PYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSA 104 Query: 1015 EGQAGAQGASDMP 1027 G+ G G P Sbjct: 105 VGKPGVPGLPGKP 117 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 63.9 bits (154), Expect = 8e-10 Identities = 97/418 (23%), Positives = 138/418 (33%), Gaps = 43/418 (10%) Query: 173 VTNTSQSQVLGNPMANANNPMNPGG--NPMASGMTTSNPGLNSPQFAGQQQQFS--AKAG 228 V++ S+ A P GG P + +++S L+SP +G + + A A Sbjct: 200 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 259 Query: 229 PAQPYIQQSMYGRPNYPGSGGFGASYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAV 288 P+QP + RP A+ GP + + + P + PP+ P+ + Sbjct: 260 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPP 319 Query: 289 AAAAATATA-----TATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQPGPRGPASMG 343 A + AT T AT + L + P P P P + Sbjct: 320 ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLS 379 Query: 344 GSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQR--MPQQTYPGPRPQSLPIQ 401 P+ A + P P PP +PF P T P P SL Sbjct: 380 PLATPSPQAPNALAVHLLQAPFSP-PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 438 Query: 402 NIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTSPNYPGQRMPSQPSSGQYPP 461 ++ P P + P P P P P PL +P + P Q P Sbjct: 439 PLQVPP-----------SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 487 Query: 462 PTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHSPVPGNPTPPMT 521 P + P F GQ FS S+ S PP+ PV P VP P+PP + Sbjct: 488 PLQALPS--PPASFPGQ-APFSPSASLPMSP-LATPPPQAPPVLAAPLLQVP--PSPPAS 541 Query: 522 P---GSSIPPYLSPSQDVK-----------PPFPPDIKPNMSALPPPPANHNDELRLT 565 P PP P V PP PP P+ + P A H+ T Sbjct: 542 PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST 599 Score = 58.2 bits (139), Expect = 4e-08 Identities = 71/285 (24%), Positives = 91/285 (31%), Gaps = 63/285 (22%) Query: 318 GPMGPTQAYNSQFMNQPGP---RGPASMGGSMNPASMAAGMTPSGMSGP----------- 363 GP + + +P P R P++ GG PAS + + + +S P Sbjct: 195 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP 254 Query: 364 --PMGMNQPRPPGI------------------------SPFGTHGQRMPQQTYPGPRPQS 397 P +QP+P G+ SP T P P Q+ Sbjct: 255 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQT 314 Query: 398 LPIQNIKRPYPGEPNYGNQQYGPNSQF----PTQPGQYPAPNPPRPLTSPNYPGQRMPSQ 453 LP P + G+ F P P P P P L P P Q PS Sbjct: 315 LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP--PLQAPPSP 372 Query: 454 PSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPVANYPHSPVP 513 P+S P Q + FS P P P P SP Sbjct: 373 PASPPLSPLATPSPQAPNALAVHLLQAPFS---------------PPPSPPVQAPFSPPA 417 Query: 514 GNP-TPPMTPGSSIPPYLSPSQDVKPPFPPDIKP-NMSALPPPPA 556 P +P TP S PP L+ PP PP P + SA PPP A Sbjct: 418 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 462 Score = 43.1 bits (100), Expect = 0.001 Identities = 60/216 (27%), Positives = 77/216 (35%), Gaps = 37/216 (17%) Query: 840 IPSKRFKTMSPSQMIMPNVMEMIAALGPGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNF 899 + S T SPS P+ + L PSP P PP T S Sbjct: 290 LSSSPLATPSPSAPPSPSAPPSLQTL---PSP-PATPPSQATTSL--------------- 330 Query: 900 DFPHGNPGGTSMNDFMHGPP--QLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHP 957 G+P + + F+ PP L+ PP P AL P P+Q A S P Sbjct: 331 ----GSPTLQATHSFLPSPPLSPLATPP--PQAPPALALP---PLQ-----APPSPPASP 376 Query: 958 SIQQGLHVPHPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEGQ 1017 + L P P + + +H AP PP PP Q P + P+S P S PS A Sbjct: 377 PLSP-LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 435 Query: 1018 AGAQ-GASDMPEPSLDLLPELTNPDELLSYLDPPDL 1052 A P S + P T P + L P L Sbjct: 436 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 471 Score = 37.4 bits (85), Expect = 0.076 Identities = 58/234 (24%), Positives = 71/234 (30%), Gaps = 25/234 (10%) Query: 837 PDGIPSKRFKTMSPSQMIMPNVMEMIAALGPGPSP---YPLPPP--PGGTNSNDYSSQGN 891 P P T SP V + A P PSP P PP P + S SQ Sbjct: 373 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 432 Query: 892 NYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGS 951 P P M+ PPQ P P A P + P T P Sbjct: 433 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQAL 492 Query: 952 SDQPHPSIQQGLHVPHPSSQSGPPLHHSGAPPP--------PPSQPPRQPPQAAPSSHPH 1003 P Q P S P+ PPP P Q P PP + P Sbjct: 493 PSPPASFPGQAPFSPSASL----PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 548 Query: 1004 SDLTFNPSSALEGQAGAQGASDMPEPSLDLLPELTNPDELLSYLDPPDLPSNSN 1057 T P +++ G + P P P +P LS PDL +S+ Sbjct: 549 RPPTPGPDTSVSGPRLTLALAPGPPP-----PPSRSPSSTLS---GPDLAGHSS 594 Score = 37.0 bits (84), Expect = 0.099 Identities = 71/317 (22%), Positives = 99/317 (31%), Gaps = 53/317 (16%) Query: 267 PPHTRPPADFTQPAAAAAAAAVAAAAATATATATATV--AALQETQNKDINQYGPMGPTQ 324 P RPP T PAA A A A + A + E+ + GPT+ Sbjct: 30 PGSPRPPPPVT-PAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR-------AGPTR 81 Query: 325 AYNSQFMNQPGPRGPASMGGSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQR 384 R PAS G P + P G G +P P G G R Sbjct: 82 T----------SRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP-----GPLGQKGLR 126 Query: 385 MPQQ-------TYPGPRPQSLPI---QNIKRPYPGEPNYG----NQQYGPNSQFPTQPGQ 430 + + P+ +L ++ P PG P+ ++ G P +P Sbjct: 127 ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP-RPAP 185 Query: 431 YPAPNPPR--PLTSPNYPGQRMPSQPSSGQYPPPTVNMG-QYYKPEQFNGQNNTFSGSSY 487 P PP P S + + ++PS P+ G Q + S + Sbjct: 186 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 245 Query: 488 SNYSQGNVNR----PPRPVP----VANYPHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPP 539 S S R P +P P P P P S P +PS P Sbjct: 246 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPP- 304 Query: 540 FPPDIKPNMSALPPPPA 556 P P++ LP PPA Sbjct: 305 -SPSAPPSLQTLPSPPA 320 Score = 36.6 bits (83), Expect = 0.13 Identities = 35/120 (29%), Positives = 47/120 (39%), Gaps = 15/120 (12%) Query: 919 PQLSHPPDMPNNMAA--LEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPL 976 P + PP P +AA L+ P S P T+ P P +S SGP L Sbjct: 515 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD----------TSVSGPRL 564 Query: 977 HHSGAP--PPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEGQAGAQ-GASDMPEPSLDL 1033 + AP PPPPS+ P + S T P +G + GA+ P P +L Sbjct: 565 TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL 624 Score = 33.5 bits (75), Expect = 1.1 Identities = 45/170 (26%), Positives = 60/170 (35%), Gaps = 51/170 (30%) Query: 864 ALGPGPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSH 923 AL PGP PPPP + S+ S G + GH + TS + + G Sbjct: 567 ALAPGP-----PPPPSRSPSSTLS--GPDLAGHSS--------SATSTPEELRG------ 605 Query: 924 PPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQS---GPPLHHSG 980 ++ P G++ P P + L HP++ S PPL G Sbjct: 606 -------------------YDSGPEGGAAASPPPDAE--LAACHPAAWSRGPAPPLAFRG 644 Query: 981 APPPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEGQAGAQGASDMPEPS 1030 AP P PP P +A T + E A GA D P PS Sbjct: 645 APGAPLPWPPATGPGSADGL-----CTIYETEGPESATPAPGALD-PGPS 688 Score = 32.7 bits (73), Expect = 1.9 Identities = 37/128 (28%), Positives = 50/128 (39%), Gaps = 14/128 (10%) Query: 928 PNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVP-HPSSQSGPPLHHSGAPPPPP 986 P+ L++P S + + S + PS + P HPS L A PP Sbjct: 219 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ---ALRPPQ 275 Query: 987 SQPPRQPPQAAPSSHPHSDLTFNPSSALEGQAGAQGASDMPEPSLDLLPE--LTNPDELL 1044 PPR+ AAP+ P S SS L + + S PSL LP T P + Sbjct: 276 VTPPRK--DAAPALGPLS------SSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQAT 327 Query: 1045 SYLDPPDL 1052 + L P L Sbjct: 328 TSLGSPTL 335 >gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo sapiens] Length = 1560 Score = 63.9 bits (154), Expect = 8e-10 Identities = 135/582 (23%), Positives = 180/582 (30%), Gaps = 148/582 (25%) Query: 120 PGKLPMQPP----LSSMSSMKPTLSHSDGSFPYDSV-------PWQQNTN----QPPGSL 164 PG LP QP L+ M++ K + FP ++ P T QPPG+L Sbjct: 384 PGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGAL 443 Query: 165 SVVTTVWGVTNTSQSQVLGNPMANANN-------------------PMNPGGN------P 199 S +V + S + M N P N GG P Sbjct: 444 SKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAP 503 Query: 200 MASGMTTSNPGLNSPQFAGQQQQ---FSAKAGPAQPYI---------QQSMYGRPNYPGS 247 G +NP L + AG + +G +I Q +++ P + Sbjct: 504 HTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAA 563 Query: 248 GGFGASYPGGPNAPA------GMGIPPHT----RPPADFTQPAAAAAAAAVAAAAATAT- 296 G P PA G+ +PP P QPA AAA AA T Sbjct: 564 GSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQP 623 Query: 297 ------ATATATVAALQETQNKDINQYGPMGPT-QAYNSQFMNQPGPRGPASMGGSMNPA 349 A +T LQ+ Q Q P PT QA P P S G + +P Sbjct: 624 APQAPPAVSTPLPLGLQQPQA----QQPPQAPTPQAAAPPQATTPQP----SPGLASSPE 675 Query: 350 SMAAGMTPSG--------------------------------------MSGPPMGMNQ-P 370 + G PS +S PP + P Sbjct: 676 KIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAP 735 Query: 371 RPPGISPFGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPGE-PNYGNQQYGPNSQFPTQPG 429 P G Q Q P P PQ +K P P P+ +Q P P P Sbjct: 736 ATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQ--APLGDSPHLPS 793 Query: 430 QYPAPNPPRPLTSPNYPGQRMPSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSN 489 +P P RP + P R PS+P PPP P F QN SN Sbjct: 794 PHPTRPPSRPPSRPQSVS-RPPSEPPLHPCPPP---QAPPTLPGIFVIQNQLGVPPPASN 849 Query: 490 YSQGNVNRPPRPV-PVANYPHSPVPGNP-TPPMTPGSSI--------------------- 526 + P P+ P + P P+P P PP + S++ Sbjct: 850 PAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQ 909 Query: 527 -PPYLSPSQDVKPPFPPDIKPNMSALPPPPANHNDELRLTFP 567 PP P + PP + P +A PPPP + FP Sbjct: 910 FPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFP 951 Score = 50.8 bits (120), Expect = 7e-06 Identities = 112/493 (22%), Positives = 160/493 (32%), Gaps = 107/493 (21%) Query: 172 GVTNTSQSQVLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQQQFSAKAGPAQ 231 GV Q+ P A A + G P A P + AG+ Q +G Sbjct: 357 GVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPA 416 Query: 232 PYIQQSMYGRPNYPGSGGFGASYPGGPNAP---------AGMGIPPHTRPPA--DFTQPA 280 P +Q +++ +P +G PG + P + + IP P F P Sbjct: 417 PALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPG 476 Query: 281 AAAAAAAVAAAAATATATATATVAALQETQNKDI--------NQYGP--MGPTQAYNS-- 328 A A +A A AA T + I N GP +GP A +S Sbjct: 477 APAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGA 536 Query: 329 ------------------------------QFMNQPGPRGPAS----MGGSMNPASMAAG 354 +QP P GPA+ G ++ P+++A Sbjct: 537 HSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAML 596 Query: 355 MTPSGMSGP-----------PMGMNQP---RPPGISPFGTHGQRMPQQTYP--GPRPQSL 398 TP G+ P P+ QP PP +S G + PQ P P PQ+ Sbjct: 597 NTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAA 656 Query: 399 --PIQNIKRPYPGEPN------YGNQQYGPNSQFPTQPGQ---YPAPNPPRPLTSP---- 443 P +P PG + G + TQ P +PL++ Sbjct: 657 APPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHL 716 Query: 444 NYPGQRMPSQPSSGQYPPPT--VNMGQYYKPEQFNGQNNTFSG----SSYSNYSQGNVNR 497 + P + S P Q P P V G P+ + Q + ++ G + Sbjct: 717 SVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSS 776 Query: 498 P--PRPVPVANYPHSPVPGNPTPPMTPGS-----SIPPYLSPSQDVKPPFPPDIKP---- 546 P P P+ + PH P P PP P S S PP P PP P P Sbjct: 777 PSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFV 836 Query: 547 --NMSALPPPPAN 557 N +PPP +N Sbjct: 837 IQNQLGVPPPASN 849 Score = 45.1 bits (105), Expect = 4e-04 Identities = 51/182 (28%), Positives = 67/182 (36%), Gaps = 36/182 (19%) Query: 863 AALGP-------GPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFM 915 A LGP P+P P P SS + PH P G D Sbjct: 743 AGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPS---------LPHQAPLG----DSP 789 Query: 916 HGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPS------IQQGLHVPHPS 969 H P HP P+ + + +S P E H Q P+ IQ L VP P+ Sbjct: 790 HLPSP--HPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPA 847 Query: 970 SQSGPPLHHSGAPPPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEGQA-GAQGASDMPE 1028 S P + PP PP +P QPP+ PH PSS A ++ +S +P Sbjct: 848 SNPAPT---APGPPQPPLRPQSQPPEGPLPPAPH----LPPSSTSSAVASSSETSSRLPA 900 Query: 1029 PS 1030 P+ Sbjct: 901 PT 902 Score = 35.8 bits (81), Expect = 0.22 Identities = 48/159 (30%), Positives = 55/159 (34%), Gaps = 29/159 (18%) Query: 902 PHGNPGGTSMNDFMHGPPQ-----LSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPH 956 P NP T+ GPPQ S PP+ P A P S SS P Sbjct: 846 PASNPAPTAP-----GPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPA 900 Query: 957 PSIQ---------QGLHVPHPSSQSGPPLHHSGAPPPPPSQPPR------QPPQAAPSSH 1001 P+ QG PH S P LH P PP PPR P A P Sbjct: 901 PTPSDFQLQFPPSQG---PHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPK 957 Query: 1002 PHSDLTFNPSSALEGQAGAQGASDMPEPSLDLLPELTNP 1040 + S + Q A GA P+ S L P LT+P Sbjct: 958 ALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGP-LTSP 995 >gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] Length = 1336 Score = 63.2 bits (152), Expect = 1e-09 Identities = 96/392 (24%), Positives = 123/392 (31%), Gaps = 84/392 (21%) Query: 195 PGGNPMAS---GMTTSNPGLNSPQFAGQ------QQQFSAKAGPAQPYIQQSMYGRPNYP 245 PG PM+ G +P P Q Q QF P P Q G P + Sbjct: 589 PGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFR----PPGPQGQMGPQGPPLHQ 644 Query: 246 GSGGFGASYPGGPNAPAGMGIPPHTRP-PADFTQPAAAAAAAAVAAAAATATATATATVA 304 G GG P G P G PP P P D P Sbjct: 645 GGGG-----PQGFMGPQGPQGPPQGLPRPQDMHGP------------------------- 674 Query: 305 ALQETQNKDINQYGPMGPTQAYNSQFMNQP----GPRGPASMGGSMNPASMAAGMTPSGM 360 + + +GP+GP Q + P GP+GP G + P G Sbjct: 675 ---QGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGP 731 Query: 361 SGPPMGMNQPRPPGISPFGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGP 420 GPP PPG P G G P GP Q I+ P P G G Sbjct: 732 QGPPGTQGMQGPPG--PRGMQGPPHPHGIQGGPGS-----QGIQGPVSQGPLMGLNPRGM 784 Query: 421 NSQFPTQPGQYPAP------NPPRPLTSPNYPG---------QRMPSQPSSGQYPPPTVN 465 + Q PAP +PP+ + P+ PG R P + Q PPP + Sbjct: 785 QGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGS 844 Query: 466 MGQYYKPEQFNGQNNTFS-----GSSYSNYSQGNVNRPPRPVPVANYPHSPVPGNPTPPM 520 M P++ G + S S QG + PP P N P P P Sbjct: 845 M--LGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPF 902 Query: 521 ----TPGSSIPPYLSPSQDVKPPFPPDIKPNM 548 TP P +Q+ + PP + P + Sbjct: 903 QQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGL 934 Score = 53.5 bits (127), Expect = 1e-06 Identities = 89/364 (24%), Positives = 111/364 (30%), Gaps = 57/364 (15%) Query: 119 PPGKLPMQPPLSSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWGVTNTSQ 178 P G+ P M P L H G P + Q PP L + G + Sbjct: 622 PQGQFRPPGPQGQMGPQGPPL-HQGGGGPQGFMG-PQGPQGPPQGLPRPQDMHGPQGMQR 679 Query: 179 SQVLGNPMANANNPMNPGGNPMASGMTTSNP-GLNSPQFAGQQQQFSAKAGPAQPYIQQS 237 + P+ P G P G +S P G PQ Q GP P Q Sbjct: 680 HP-------GPHGPLGPQGPPGPQG--SSGPQGHMGPQGPPGPQGHIGPQGPPGP---QG 727 Query: 238 MYGRPNYPGSGGFGASYPGGPNAPAGMGIPPHTR-----PPADFTQ------PAAAAAAA 286 G PG+ G GP P GM PPH P + Q P Sbjct: 728 HLGPQGPPGTQGMQ-----GPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPR 782 Query: 287 AVAAAAATATATATATVAALQETQNKDINQYGPMGPTQAYNSQFMNQP----GPRGPASM 342 + A + +++ P G + Q M P G +GP Sbjct: 783 GMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQ 842 Query: 343 GGSMNPASMAAGMTPS-GMSGPPMGMNQPRPPG--ISPFGTHGQRMPQQTYPGPRPQSLP 399 G + P G S GPP G P P G P G GQ+ P + P P +P Sbjct: 843 GSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARG-PHPSQGPIP 901 Query: 400 IQNIKRPYPGEP-----NYGNQQYGPNSQFP-------------TQPGQYPAPNPPRPLT 441 Q K P G+ N Q GP P PGQ P PN Sbjct: 902 FQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRG 961 Query: 442 SPNY 445 PN+ Sbjct: 962 PPNH 965 Score = 45.4 bits (106), Expect = 3e-04 Identities = 52/187 (27%), Positives = 63/187 (33%), Gaps = 30/187 (16%) Query: 845 FKTMSPSQMIMPNVMEMIAALGPGPSPYPLPPPPGGT---NSNDYSSQGNNYQGHGNFDF 901 F+ PSQ + N+ +M PGP PP P G G QG Sbjct: 601 FQQPHPSQQMPMNMAQMGP---PGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQG 657 Query: 902 PHGNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQ 961 P G P G MHGP + P + P H G P P Q Sbjct: 658 PQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGP---Q 714 Query: 962 GLHVPHPSSQSGP-PLHHSGAPPPPPSQPPRQPP-----QAAPSSHPHSDLTFNPSSALE 1015 G H Q P P H G PP +Q + PP Q P HPH ++ Sbjct: 715 G----HIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPP--HPH---------GIQ 759 Query: 1016 GQAGAQG 1022 G G+QG Sbjct: 760 GGPGSQG 766 Score = 42.0 bits (97), Expect = 0.003 Identities = 64/233 (27%), Positives = 75/233 (32%), Gaps = 48/233 (20%) Query: 837 PDGIPSKRFKTMSPSQMIMPNVMEMIAALGPGPSPYPLPP--PPGGTNSNDYSSQGNNYQ 894 P G+P P M P M+ PGP PL P PPG S+ Q Sbjct: 662 PQGLPR-------PQDMHGPQGMQR----HPGPHG-PLGPQGPPGPQGSS-------GPQ 702 Query: 895 GHGNFDFPHGNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQ 954 GH P G PG H PQ PP ++ P + MQ G Sbjct: 703 GHMG---PQGPPGPQG-----HIGPQ--GPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGP 752 Query: 955 PHP-SIQ-----QGLHVP---------HPSSQSGPPLHHSGAPPPPPSQPPRQPPQAAPS 999 PHP IQ QG+ P +P GPP P P PPQ Sbjct: 753 PHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRG 812 Query: 1000 SHPHSDLTFNPSSALEGQAGAQGASDMPEPSLDLLP--ELTNPDELLSYLDPP 1050 HP L + + G +G P L P EL P S PP Sbjct: 813 PHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPP 865 Score = 37.4 bits (85), Expect = 0.076 Identities = 41/154 (26%), Positives = 48/154 (31%), Gaps = 20/154 (12%) Query: 867 PGPSPYPLPPPPGGTNSNDYSS-----------QGNNYQGHGNFDFPHGNPGGTSMNDFM 915 PGP PP P G S G N +G P N G M Sbjct: 744 PGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIM 803 Query: 916 HGPPQLSHPPDMPNNMAA-----LEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSS 970 PPQ P P + + P + P GS P ++ P S Sbjct: 804 GHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGP---PGSQS 860 Query: 971 QSGPPLHHSGAPPPPPSQ-PPRQPPQAAPSSHPH 1003 Q GPP G PP Q PP Q P+ PH Sbjct: 861 QQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPH 894 Score = 36.2 bits (82), Expect = 0.17 Identities = 38/136 (27%), Positives = 43/136 (31%), Gaps = 32/136 (23%) Query: 902 PHGNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQ 961 P PG M+ G Q MP NMA + P G Q P Q Sbjct: 585 PQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPP------------GPQGQFRPPGPQ 632 Query: 962 GLHVPHPSSQSGPPLHHSGAPPP--PPSQPPRQPPQAAPSSH-------------PHSDL 1006 G P GPPLH G P Q P+ PPQ P PH L Sbjct: 633 GQMGP-----QGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPL 687 Query: 1007 TFNPSSALEGQAGAQG 1022 +G +G QG Sbjct: 688 GPQGPPGPQGSSGPQG 703 Score = 32.7 bits (73), Expect = 1.9 Identities = 50/190 (26%), Positives = 64/190 (33%), Gaps = 41/190 (21%) Query: 383 QRMPQQTYPGPRPQSLPIQNIKRPYPGEPNY-----GNQQYGPNSQFPTQPGQYPAPNPP 437 Q+ +Q P P P+ +P+PG+ G QQ P+ Q P Q P P Sbjct: 566 QKQVEQIQPPPS-SGTPLLG-PQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQ 623 Query: 438 RPLTSPNYPGQRMPSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNR 497 P GQ P Q PP G P+ F G QG Sbjct: 624 GQFRPPGPQGQMGP------QGPPLHQGGG---GPQGFMGPQG----------PQGPPQG 664 Query: 498 PPRPVPVAN--------YPHSPVPGNPTPPMTPGSSIPPYLSPSQDVKPPFPPDIKPNMS 549 PRP + PH P+ G PP GSS P + P PP + ++ Sbjct: 665 LPRPQDMHGPQGMQRHPGPHGPL-GPQGPPGPQGSS-----GPQGHMGPQGPPGPQGHIG 718 Query: 550 AL-PPPPANH 558 PP P H Sbjct: 719 PQGPPGPQGH 728 Score = 32.7 bits (73), Expect = 1.9 Identities = 27/91 (29%), Positives = 34/91 (37%), Gaps = 11/91 (12%) Query: 941 PMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSGAPPPPPS---QPPRQPPQAA 997 P+ P G P I QG PHPS Q P++ + PP P +PP Q Sbjct: 581 PLLGPQPFPGQG--PMSQIPQGFQQPHPSQQM--PMNMAQMGPPGPQGQFRPPGPQGQMG 636 Query: 998 PSSHPHSDLTFNPSSALEGQAGAQGASDMPE 1028 P P P +G G QG P+ Sbjct: 637 PQGPPLHQGGGGP----QGFMGPQGPQGPPQ 663 Score = 32.3 bits (72), Expect = 2.4 Identities = 39/175 (22%), Positives = 50/175 (28%), Gaps = 19/175 (10%) Query: 868 GPSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPPDM 927 GP L PPP G QG G PH + G P L P Sbjct: 863 GPPQGSLGPPPQGGMQGPPGPQGQQNPARG----PHPSQGPIPFQQ--QKTPLLGDGPRA 916 Query: 928 PNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGPPLHHSGAPPPPPS 987 P N + P+ + G+ + P P+ GPP HH G P Sbjct: 917 PFNQEG-QSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMG-----PM 970 Query: 988 QPPRQPPQAAPSSHPHSDLTFNPSSALEGQAGAQGASDMPEPSLDLLPELTNPDE 1042 R P P G +G D P D + + PD+ Sbjct: 971 SERRHEQSGGPEHGPE-------RGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDD 1018 >gi|116284398 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 62.8 bits (151), Expect = 2e-09 Identities = 93/383 (24%), Positives = 132/383 (34%), Gaps = 68/383 (17%) Query: 196 GGNPMASGMTTSN-PGLNSPQFAGQQQQFSAKAGPAQPYIQQSMYGRPNYP--GSGGFGA 252 GG P G+ + P L S A + P P +S +P P G G F Sbjct: 95 GGPPGLGGLFQAGMPKLRST--ANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPV 152 Query: 253 SYPG---GPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATATATATATVAALQET 309 PG GP P +PP P D V + + +T +Q + Sbjct: 153 PSPGHRSGPPEPQRNRMPP---PRPD------------VGSKPDSIPPPVPSTPRPIQSS 197 Query: 310 QNKDINQYGPMGPTQAYNSQFMNQ-PGPRGPASMGGSMNPASMAAGMTPSGMSGPPMGMN 368 + + P GP Q PG RG A GGS+ + ++ S P Sbjct: 198 PHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLS--------SSSPFSNR 249 Query: 369 QPRPPGISPFGTHGQRMPQQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGPNSQFPTQP 428 P PP T + + + P P P + P P N+ P++ P+ Sbjct: 250 PPLPP------TPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSAS 303 Query: 429 GQYPAPNPPRPLTSPNYPGQRMPSQPSSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYS 488 Q P P PP PS+P PP + + + Q N ++ + S Sbjct: 304 SQAPPPPPP-------------PSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPS 350 Query: 489 NYSQGNVNRPPR---PVPVANYPHSPVPGNPTPPMTPGSSIPPYL-------------SP 532 G + PP P PV + P P P PP++ S L SP Sbjct: 351 PGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSP 410 Query: 533 SQDVKPPFPPDIKPNMSALPPPP 555 +PP PPD +P+ A PPPP Sbjct: 411 RSGPRPPLPPD-RPSAGAPPPPP 432 Score = 51.6 bits (122), Expect = 4e-06 Identities = 98/429 (22%), Positives = 139/429 (32%), Gaps = 61/429 (14%) Query: 109 LRHQKSRQSDPPG-KLPMQPPLSSMSSMKPTLSHSD-GSFPYDSV------PWQQNTNQP 160 LR +R +D G + P+ PP +S KP S G FP S P Q P Sbjct: 111 LRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMP 170 Query: 161 PGSLSVVTTVWGVTNTSQSQVLGNPMANANNPMNPGGNPMASGMTTSNPGLNSPQFAGQQ 220 P V + ++ V P ++P N G P+ G +PG P F G + Sbjct: 171 PPRPDVGSK----PDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNR 226 Query: 221 QQFSAKAGPAQPYIQQS--MYGRPNYPGSGGFGA-SYPGGPNAPAG-------MGIPPHT 270 Q + S RP P + P P P G +PP Sbjct: 227 GTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPP-- 284 Query: 271 RPPADFTQPAAAAAAAAVAAAAATATATATATVAALQETQNKDINQYGPMGPTQ----AY 326 PP +P + A++ A + + N P P + + Sbjct: 285 -PPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSS 343 Query: 327 NSQFMNQPGPRGPASMGGSMNPASMAAGMTPSGMSGPPMGMNQPRPPGISPFGTHGQRMP 386 ++ + PG GP S P P G SGP P PP +S G+ + +P Sbjct: 344 STPPLPSPGRSGPLPPPPSERPPPPV--RDPPGRSGP-----LPPPPPVSRNGSTSRALP 396 Query: 387 QQTYPGPRPQSLPIQNIKRPYPGEPNYGNQQYGPNSQFPTQPGQYPAPNPPRPLTSPNYP 446 PQ P + + GP P AP PP P TS Sbjct: 397 ------ATPQ----------LPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNG 440 Query: 447 GQRMPSQP--SSGQYPPPTVNMGQYYKPEQFNGQNNTFSGSSYSNYSQGNVNRPPRPVPV 504 Q P + S Y P ++ PE + ++ N S+ NR R P Sbjct: 441 FQDSPCEDEWESRFYFHPISDLP---PPEPYVQTTKSYPSKLARNESRSGSNRRERGAP- 496 Query: 505 ANYPHSPVP 513 P P+P Sbjct: 497 ---PLPPIP 502 Score = 44.3 bits (103), Expect = 6e-04 Identities = 77/282 (27%), Positives = 100/282 (35%), Gaps = 61/282 (21%) Query: 823 RPVPIKSDLHIKDDPDGIPSKRFKTMSPSQMIMPNVMEMIAALGPG-PSPYPLPPP-PG- 879 R P + D+ K PD IP T P Q N GP PSP P PPP PG Sbjct: 168 RMPPPRPDVGSK--PDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGN 225 Query: 880 -GTNSNDYSSQGNNYQGHGNF---------------DFPHGNPGGTSMNDFMHG------ 917 GT S + + F D P P +H Sbjct: 226 RGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPP 285 Query: 918 PPQLSHPP--DMPNNMAALEKPL-----SHPMQETMPHAGSSDQPHPSI-QQGLHVPHPS 969 PPQ + PP P A+ + P S P +P + S + P + Q+ L + Sbjct: 286 PPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSL---- 341 Query: 970 SQSGPPLH---HSGAPPPPPSQ----PPRQPPQAAPSSHPHSDLTFNPSSA--------L 1014 S S PPL SG PPPPS+ P R PP + P ++ N S++ L Sbjct: 342 SSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQL 401 Query: 1015 EGQAGAQGASDMPEPSLDLLPELTNPDELLSYLDPPDLPSNS 1056 ++G P P L PD + PP PS S Sbjct: 402 PSRSGVDSPRSGPRPPLP-------PDRPSAGAPPPPPPSTS 436 Score = 37.4 bits (85), Expect = 0.076 Identities = 43/153 (28%), Positives = 50/153 (32%), Gaps = 21/153 (13%) Query: 869 PSPYPLPPPPGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPPDMP 928 P P PLPP G + Q N P G PP PP Sbjct: 316 PGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLP------PPPSERPPPPV 369 Query: 929 NNMAALEKPLSHPMQETMPHAGSSDQPH-PSIQQGLHVPHPSSQSGPPLH----HSGAPP 983 + PL P + + S P P + V P S PPL +GAPP Sbjct: 370 RDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPP 429 Query: 984 PPP-SQPPRQPPQAAPSS---------HPHSDL 1006 PPP S R Q +P HP SDL Sbjct: 430 PPPPSTSIRNGFQDSPCEDEWESRFYFHPISDL 462 Score = 37.0 bits (84), Expect = 0.099 Identities = 40/155 (25%), Positives = 50/155 (32%), Gaps = 25/155 (16%) Query: 890 GNNYQGHGNFDFPHGNPGGTSMND---------FMHGPPQLSHPPDMPNNMAALEKPLSH 940 G + G G F G GG S F G P+L + N+ PL Sbjct: 71 GGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLP 130 Query: 941 PMQETMPHAGSSDQPH--PSIQQGLHVPHPSSQSGPPLHHSGAPPPP----PSQPPRQPP 994 P + +S +P PS VP P +SGPP PPP S+P PP Sbjct: 131 PGGRS-----TSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPP 185 Query: 995 QAAPSSHPHSDLTFNPSSALEGQAGAQGASDMPEP 1029 + P N G G P P Sbjct: 186 PVPSTPRPIQSSPHN-----RGSPPVPGGPRQPSP 215 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.132 0.414 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 59,361,640 Number of Sequences: 37866 Number of extensions: 4097133 Number of successful extensions: 49082 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 509 Number of HSP's successfully gapped in prelim test: 1511 Number of HSP's that attempted gapping in prelim test: 20478 Number of HSP's gapped (non-prelim): 17127 length of query: 1067 length of database: 18,247,518 effective HSP length: 113 effective length of query: 954 effective length of database: 13,968,660 effective search space: 13326101640 effective search space used: 13326101640 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.