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Search of human proteins with 24307911
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24307911 acid sphingomyelinase-like phosphodiesterase 3A
[Homo sapiens]
(453 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24307911 acid sphingomyelinase-like phosphodiesterase 3A [Hom... 940 0.0
gi|57242798 acid sphingomyelinase-like phosphodiesterase 3B isof... 357 9e-99
gi|57242800 acid sphingomyelinase-like phosphodiesterase 3B isof... 294 1e-79
gi|56117840 sphingomyelin phosphodiesterase 1, acid lysosomal is... 177 2e-44
gi|56117842 sphingomyelin phosphodiesterase 1, acid lysosomal is... 125 8e-29
gi|94158594 ADP-ribose/CDP-alcohol pyrophosphatase [Homo sapiens] 40 0.004
gi|104487002 protein tyrosine phosphatase, receptor type, D isof... 33 0.69
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor... 33 0.69
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo... 33 0.69
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 33 0.69
gi|18860894 protein tyrosine phosphatase, receptor type, D isofo... 33 0.69
gi|20336188 paired basic amino acid cleaving system 4 isoform e ... 32 0.91
gi|20336186 paired basic amino acid cleaving system 4 isoform c ... 32 0.91
gi|27894285 paired basic amino acid cleaving system 4 isoform f ... 32 0.91
gi|20336190 paired basic amino acid cleaving system 4 isoform d ... 32 0.91
gi|20336184 paired basic amino acid cleaving system 4 isoform h ... 32 0.91
gi|20336182 paired basic amino acid cleaving system 4 isoform g ... 32 0.91
gi|4505577 paired basic amino acid cleaving system 4 isoform a p... 32 0.91
gi|20336180 paired basic amino acid cleaving system 4 isoform b ... 32 0.91
gi|27436871 carboxypeptidase O [Homo sapiens] 32 1.5
gi|160420295 hypothetical protein LOC85459 [Homo sapiens] 31 2.0
gi|93277076 CDK5 regulatory subunit associated protein 1-like 1 ... 31 2.6
gi|154689817 beta 1,3-galactosyltransferase-like [Homo sapiens] 30 3.4
gi|40254462 guanine nucleotide binding protein (G protein), q po... 30 4.5
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 30 5.9
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 30 5.9
gi|11761619 GDP-mannose pyrophosphorylase B isoform 1 [Homo sapi... 30 5.9
gi|11761621 GDP-mannose pyrophosphorylase B isoform 2 [Homo sapi... 30 5.9
gi|153791876 olfactory receptor, family 6, subfamily Q, member 1... 30 5.9
gi|21493045 A-kinase anchor protein 6 [Homo sapiens] 29 7.7
>gi|24307911 acid sphingomyelinase-like phosphodiesterase 3A [Homo
sapiens]
Length = 453
Score = 940 bits (2430), Expect = 0.0
Identities = 453/453 (100%), Positives = 453/453 (100%)
Query: 1 MALVRALVCCLLTAWHCRSGLGLPVAPAGGRNPPPAIGQFWHVTDLHLDPTYHITDDHTK 60
MALVRALVCCLLTAWHCRSGLGLPVAPAGGRNPPPAIGQFWHVTDLHLDPTYHITDDHTK
Sbjct: 1 MALVRALVCCLLTAWHCRSGLGLPVAPAGGRNPPPAIGQFWHVTDLHLDPTYHITDDHTK 60
Query: 61 VCASSKGANASNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSPPHVPVPEL 120
VCASSKGANASNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSPPHVPVPEL
Sbjct: 61 VCASSKGANASNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSPPHVPVPEL 120
Query: 121 STDTVINVITNMTTTIQSLFPNLQVFPALGNHDYWPQDQLPVVTSKVYNAVANLWKPWLD 180
STDTVINVITNMTTTIQSLFPNLQVFPALGNHDYWPQDQLPVVTSKVYNAVANLWKPWLD
Sbjct: 121 STDTVINVITNMTTTIQSLFPNLQVFPALGNHDYWPQDQLPVVTSKVYNAVANLWKPWLD 180
Query: 181 EEAISTLRKGGFYSQKVTTNPNLRIISLNTNLYYGPNIMTLNKTDPANQFEWLESTLNNS 240
EEAISTLRKGGFYSQKVTTNPNLRIISLNTNLYYGPNIMTLNKTDPANQFEWLESTLNNS
Sbjct: 181 EEAISTLRKGGFYSQKVTTNPNLRIISLNTNLYYGPNIMTLNKTDPANQFEWLESTLNNS 240
Query: 241 QQNKEKVYIIAHVPVGYLPSSQNITAMREYYNEKLIDIFQKYSDVIAGQFYGHTHRDSIM 300
QQNKEKVYIIAHVPVGYLPSSQNITAMREYYNEKLIDIFQKYSDVIAGQFYGHTHRDSIM
Sbjct: 241 QQNKEKVYIIAHVPVGYLPSSQNITAMREYYNEKLIDIFQKYSDVIAGQFYGHTHRDSIM 300
Query: 301 VLSDKKGSPVNSLFVAPAVTPVKSVLEKQTNNPGIRLFQYDPRDYKLLDMLQYYLNLTEA 360
VLSDKKGSPVNSLFVAPAVTPVKSVLEKQTNNPGIRLFQYDPRDYKLLDMLQYYLNLTEA
Sbjct: 301 VLSDKKGSPVNSLFVAPAVTPVKSVLEKQTNNPGIRLFQYDPRDYKLLDMLQYYLNLTEA 360
Query: 361 NLKGESIWKLEYILTQTYDIEDLQPESLYGLAKQFTILDSKQFIKYYNYFFVSYDSSVTC 420
NLKGESIWKLEYILTQTYDIEDLQPESLYGLAKQFTILDSKQFIKYYNYFFVSYDSSVTC
Sbjct: 361 NLKGESIWKLEYILTQTYDIEDLQPESLYGLAKQFTILDSKQFIKYYNYFFVSYDSSVTC 420
Query: 421 DKTCKAFQICAIMNLDNISYADCLKQLYIKHNY 453
DKTCKAFQICAIMNLDNISYADCLKQLYIKHNY
Sbjct: 421 DKTCKAFQICAIMNLDNISYADCLKQLYIKHNY 453
>gi|57242798 acid sphingomyelinase-like phosphodiesterase 3B isoform
1 [Homo sapiens]
Length = 455
Score = 357 bits (917), Expect = 9e-99
Identities = 172/420 (40%), Positives = 253/420 (60%), Gaps = 8/420 (1%)
Query: 29 GGRNPPPAIGQFWHVTDLHLDPTYHITDDHTKVCASSKGANASNPGPFGDVLCDSPYQLI 88
GG P G+FWH+ DLHLDP Y ++ D +VC S+ + GP+GD LCDSP+ LI
Sbjct: 14 GGARAEP--GKFWHIADLHLDPDYKVSKDPFQVCPSAGSQPVPDAGPWGDYLCDSPWALI 71
Query: 89 LSAFDFIKNSGQEASFMIWTGDSPPHVPVPELSTDTVINVITNMTTTIQSLFPNLQVFPA 148
S+ +K E F++WTGD PHVP +L V+ ++ +T I+ +FP+ +V+ A
Sbjct: 72 NSSIYAMKEIEPEPDFILWTGDDTPHVPDEKLGEAAVLEIVERLTKLIREVFPDTKVYAA 131
Query: 149 LGNHDYWPQDQLPVVTSKVYNAVANLWKPWLDEEAISTLRKGGFYSQKVTTNPNL-RIIS 207
LGNHD+ P++Q P ++ +YN +A LWKPWL E+I+ +KG FY +K+ RI+
Sbjct: 132 LGNHDFHPKNQFPAGSNNIYNQIAELWKPWLSNESIALFKKGAFYCEKLPGPSGAGRIVV 191
Query: 208 LNTNLYYGPNIMTLNKTDPANQFEWLESTLNNSQQNKEKVYIIAHVPVGYLPSSQNITAM 267
LNTNLYY N +T + DP QF+WLE L ++ + + VYI+ HVP G+ +QN
Sbjct: 192 LNTNLYYTSNALTADMADPGQQFQWLEDVLTDASKAGDMVYIVGHVPPGFFEKTQNKAWF 251
Query: 268 REYYNEKLIDIFQKYSDVIAGQFYGHTHRDSIMVLSDKKGSPVNSLFVAPAVTPVKSVLE 327
RE +NEK + + +K+ VIAGQF+GH H DS +L D G P++++F+ P VTP K+ L
Sbjct: 252 REGFNEKYLKVVRKHHRVIAGQFFGHHHTDSFRMLYDDAGVPISAMFITPGVTPWKTTLP 311
Query: 328 ---KQTNNPGIRLFQYDPRDYKLLDMLQYYLNLTEANLKGESIWKLEYILTQTYDIEDLQ 384
NNP IR+F+YD L DM+ Y++NL++AN +G W+LEY LT+ Y + D
Sbjct: 312 GVVNGANNPAIRVFEYDRATLSLKDMVTYFMNLSQANAQGTPRWELEYQLTEAYGVPDAS 371
Query: 385 PESLYGLAKQFTILDSKQFIKYYNYFFVSYDSSVTCDKTCKAFQICAIMNLDNISYADCL 444
S++ + + D +YY Y VSY + V CD+ C +CA+ +D +Y CL
Sbjct: 372 AHSMHTVLDRIA-GDQSTLQRYYVYNSVSYSAGV-CDEACSMQHVCAMRQVDIDAYTTCL 429
>gi|57242800 acid sphingomyelinase-like phosphodiesterase 3B isoform
2 [Homo sapiens]
Length = 373
Score = 294 bits (752), Expect = 1e-79
Identities = 137/317 (43%), Positives = 198/317 (62%), Gaps = 6/317 (1%)
Query: 29 GGRNPPPAIGQFWHVTDLHLDPTYHITDDHTKVCASSKGANASNPGPFGDVLCDSPYQLI 88
GG P G+FWH+ DLHLDP Y ++ D +VC S+ + GP+GD LCDSP+ LI
Sbjct: 14 GGARAEP--GKFWHIADLHLDPDYKVSKDPFQVCPSAGSQPVPDAGPWGDYLCDSPWALI 71
Query: 89 LSAFDFIKNSGQEASFMIWTGDSPPHVPVPELSTDTVINVITNMTTTIQSLFPNLQVFPA 148
S+ +K E F++WTGD PHVP +L V+ ++ +T I+ +FP+ +V+ A
Sbjct: 72 NSSIYAMKEIEPEPDFILWTGDDTPHVPDEKLGEAAVLEIVERLTKLIREVFPDTKVYAA 131
Query: 149 LGNHDYWPQDQLPVVTSKVYNAVANLWKPWLDEEAISTLRKGGFYSQKVTTNPNL-RIIS 207
LGNHD+ P++Q P ++ +YN +A LWKPWL E+I+ +KG FY +K+ RI+
Sbjct: 132 LGNHDFHPKNQFPAGSNNIYNQIAELWKPWLSNESIALFKKGAFYCEKLPGPSGAGRIVV 191
Query: 208 LNTNLYYGPNIMTLNKTDPANQFEWLESTLNNSQQNKEKVYIIAHVPVGYLPSSQNITAM 267
LNTNLYY N +T + DP QF+WLE L ++ + + VYI+ HVP G+ +QN
Sbjct: 192 LNTNLYYTSNALTADMADPGQQFQWLEDVLTDASKAGDMVYIVGHVPPGFFEKTQNKAWF 251
Query: 268 REYYNEKLIDIFQKYSDVIAGQFYGHTHRDSIMVLSDKKGSPVNSLFVAPAVTPVKSVLE 327
RE +NEK + + +K+ VIAGQF+GH H DS +L D G P++++F+ P VTP K+ L
Sbjct: 252 REGFNEKYLKVVRKHHRVIAGQFFGHHHTDSFRMLYDDAGVPISAMFITPGVTPWKTTLP 311
Query: 328 ---KQTNNPGIRLFQYD 341
NNP IR+F+YD
Sbjct: 312 GVVNGANNPAIRVFEYD 328
>gi|56117840 sphingomyelin phosphodiesterase 1, acid lysosomal
isoform 1 precursor [Homo sapiens]
Length = 631
Score = 177 bits (448), Expect = 2e-44
Identities = 139/462 (30%), Positives = 215/462 (46%), Gaps = 53/462 (11%)
Query: 11 LLTAWHCRSGLGLPVAPAGGRNPP--PAIG----QFWHVTDLHLDPTYHITDD----HTK 60
+ ++W+ + LP P PP PA G + +TDLH D Y D
Sbjct: 172 IFSSWN----ISLPTVPKPPPKPPSPPAPGAPVSRILFLTDLHWDHDYLEGTDPDCADPL 227
Query: 61 VCASSKGAN-ASNPGP--FGDVL-CDSPYQLILSAFDFIKNSGQEASFMIWTGDSPPHVP 116
C G AS PG +G+ CD P + + S + +G + WTGD P H
Sbjct: 228 CCRRGSGLPPASRPGAGYWGEYSKCDLPLRTLESLLSGLGPAGP-FDMVYWTGDIPAHDV 286
Query: 117 VPELSTDTVINVITNMTTTIQSLFPNLQVFPALGNHDYWPQDQLPVVTSK-------VYN 169
+ D + +T +T ++ + V+PA+GNH+ P + P + +Y
Sbjct: 287 WHQTRQDQ-LRALTTVTALVRKFLGPVPVYPAVGNHESTPVNSFPPPFIEGNHSSRWLYE 345
Query: 170 AVANLWKPWLDEEAISTLRKGGFYSQKVTTNPNLRIISLNTNLYYGPNI-MTLNKTDPAN 228
A+A W+PWL EA+ TLR GGFY+ ++ P LR+ISLN N N + +N TDPA
Sbjct: 346 AMAKAWEPWLPAEALRTLRIGGFYA--LSPYPGLRLISLNMNFCSRENFWLLINSTDPAG 403
Query: 229 QFEWLESTLNNSQQNKEKVYIIAHVPVGYLPSSQNITAMREYYNEKLIDIFQKYSDVIAG 288
Q +WL L ++ +KV+II H+P G+ S + YY I +Y + +A
Sbjct: 404 QLQWLVGELQAAEDRGDKVHIIGHIPPGHCLKSWS----WNYYR-----IVARYENTLAA 454
Query: 289 QFYGHTHRDSIMVLSDKK--GSPVNSLFVAPAVTPVKSVLEKQTNNPGIRLFQ----YDP 342
QF+GHTH D V D++ P+ F+AP+ T + NPG R++Q Y
Sbjct: 455 QFFGHTHVDEFEVFYDEETLSRPLAVAFLAPSATTYIGL------NPGYRVYQIDGNYSG 508
Query: 343 RDYKLLDMLQYYLNLTEANLKGE-SIWKLEYILTQTYDIEDLQPESLYGLAKQFTILDSK 401
+ +LD Y LNLT+AN+ G W+L Y +TY + + P + + L + D +
Sbjct: 509 SSHVVLDHETYILNLTQANIPGAIPHWQLLYRARETYGLPNTLPTAWHNLVYRMR-GDMQ 567
Query: 402 QFIKYYNYFFVSYDSSVTCDKTCKAFQICAIMNLDNISYADC 443
F ++ + + S C C+ +CA ++ S A C
Sbjct: 568 LFQTFWFLYHKGHPPSEPCGTPCRLATLCAQLSARADSPALC 609
>gi|56117842 sphingomyelin phosphodiesterase 1, acid lysosomal
isoform 2 precursor [Homo sapiens]
Length = 587
Score = 125 bits (314), Expect = 8e-29
Identities = 122/461 (26%), Positives = 189/461 (40%), Gaps = 95/461 (20%)
Query: 11 LLTAWHCRSGLGLPVAPAGGRNPP--PAIG----QFWHVTDLHLDPTYHITDD----HTK 60
+ ++W+ + LP P PP PA G + +TDLH D Y D
Sbjct: 172 IFSSWN----ISLPTVPKPPPKPPSPPAPGAPVSRILFLTDLHWDHDYLEGTDPDCADPL 227
Query: 61 VCASSKGAN-ASNPGP--FGDVL-CDSPYQLILSAFDFIKNSGQEASFMIWTGDSPPHVP 116
C G AS PG +G+ CD P + + S + +G + WTGD P H
Sbjct: 228 CCRRGSGLPPASRPGAGYWGEYSKCDLPLRTLESLLSGLGPAGP-FDMVYWTGDIPAHDV 286
Query: 117 VPELSTDTVINVITNMTTTIQSLFPNLQVFPALGNHDYWPQDQLPVVTSK-------VYN 169
+ D + +T +T ++ + V+PA+GNH+ P + P + +Y
Sbjct: 287 WHQTRQDQ-LRALTTVTALVRKFLGPVPVYPAVGNHESTPVNSFPPPFIEGNHSSRWLYE 345
Query: 170 AVANLWKPWLDEEAISTLRKGGFYSQKVTTNPNLRIISLNTNLYYGPNIMTLNKTDPANQ 229
A+A W+PWL EA+ TLR Y V T
Sbjct: 346 AMAKAWEPWLPAEALRTLR----YLSSVET------------------------------ 371
Query: 230 FEWLESTLNNSQQNKEKVYIIAHVPVGYLPSSQNITAMREYYNEKLIDIFQKYSDVIAGQ 289
Q+ K KV+II H+P G+ S + YY I +Y + +A Q
Sbjct: 372 -----------QEGKRKVHIIGHIPPGHCLKSWSWN----YYR-----IVARYENTLAAQ 411
Query: 290 FYGHTHRDSIMVLSDKK--GSPVNSLFVAPAVTPVKSVLEKQTNNPGIRLFQ----YDPR 343
F+GHTH D V D++ P+ F+AP+ T + NPG R++Q Y
Sbjct: 412 FFGHTHVDEFEVFYDEETLSRPLAVAFLAPSATTYIGL------NPGYRVYQIDGNYSGS 465
Query: 344 DYKLLDMLQYYLNLTEANLKGE-SIWKLEYILTQTYDIEDLQPESLYGLAKQFTILDSKQ 402
+ +LD Y LNLT+AN+ G W+L Y +TY + + P + + L + D +
Sbjct: 466 SHVVLDHETYILNLTQANIPGAIPHWQLLYRARETYGLPNTLPTAWHNLVYRMR-GDMQL 524
Query: 403 FIKYYNYFFVSYDSSVTCDKTCKAFQICAIMNLDNISYADC 443
F ++ + + S C C+ +CA ++ S A C
Sbjct: 525 FQTFWFLYHKGHPPSEPCGTPCRLATLCAQLSARADSPALC 565
>gi|94158594 ADP-ribose/CDP-alcohol pyrophosphatase [Homo sapiens]
Length = 342
Score = 40.0 bits (92), Expect = 0.004
Identities = 25/80 (31%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 216 PNIMTLNKTDPANQFEWLESTLNNSQQNKEKVYIIAHVPVGYLPSSQNITAMREYYNEKL 275
P + N Q WL L S N+EKV I++H+P+ Y +S N+ + Y + L
Sbjct: 205 PQFVQFNGGFSQEQLNWLNEVLTFSDTNQEKVVIVSHLPI-YPDASDNV-CLAWNYRDAL 262
Query: 276 IDIFQKYSDVIAGQFYGHTH 295
I+ + + F GHTH
Sbjct: 263 AVIWS--HECVVCFFAGHTH 280
>gi|104487002 protein tyrosine phosphatase, receptor type, D isoform 5
precursor [Homo sapiens]
Length = 1502
Score = 32.7 bits (73), Expect = 0.69
Identities = 28/112 (25%), Positives = 47/112 (41%), Gaps = 12/112 (10%)
Query: 187 LRKGGFYSQKVTTNPNLRIISL---------NTNLYYGPNIMTLNKTDPANQFEWLESTL 237
LR+ F + + ++P + I+ L N NL + ++ DP QF W S L
Sbjct: 911 LRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESI---DPGQQFTWEHSNL 967
Query: 238 NNSQQNKEKVYIIAHVPVGYLPSSQNITAMREYYNEKLIDIFQKYSDVIAGQ 289
++ +IA+ L S+ +Y N ID ++K + IA Q
Sbjct: 968 EVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQ 1019
>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
precursor [Homo sapiens]
Length = 1912
Score = 32.7 bits (73), Expect = 0.69
Identities = 28/112 (25%), Positives = 47/112 (41%), Gaps = 12/112 (10%)
Query: 187 LRKGGFYSQKVTTNPNLRIISL---------NTNLYYGPNIMTLNKTDPANQFEWLESTL 237
LR+ F + + ++P + I+ L N NL + ++ DP QF W S L
Sbjct: 1321 LRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESI---DPGQQFTWEHSNL 1377
Query: 238 NNSQQNKEKVYIIAHVPVGYLPSSQNITAMREYYNEKLIDIFQKYSDVIAGQ 289
++ +IA+ L S+ +Y N ID ++K + IA Q
Sbjct: 1378 EVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQ 1429
>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform 2
precursor [Homo sapiens]
Length = 1899
Score = 32.7 bits (73), Expect = 0.69
Identities = 28/112 (25%), Positives = 47/112 (41%), Gaps = 12/112 (10%)
Query: 187 LRKGGFYSQKVTTNPNLRIISL---------NTNLYYGPNIMTLNKTDPANQFEWLESTL 237
LR+ F + + ++P + I+ L N NL + ++ DP QF W S L
Sbjct: 1308 LRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESI---DPGQQFTWEHSNL 1364
Query: 238 NNSQQNKEKVYIIAHVPVGYLPSSQNITAMREYYNEKLIDIFQKYSDVIAGQ 289
++ +IA+ L S+ +Y N ID ++K + IA Q
Sbjct: 1365 EVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQ 1416
>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform 3
precursor [Homo sapiens]
Length = 1903
Score = 32.7 bits (73), Expect = 0.69
Identities = 28/112 (25%), Positives = 47/112 (41%), Gaps = 12/112 (10%)
Query: 187 LRKGGFYSQKVTTNPNLRIISL---------NTNLYYGPNIMTLNKTDPANQFEWLESTL 237
LR+ F + + ++P + I+ L N NL + ++ DP QF W S L
Sbjct: 1312 LRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESI---DPGQQFTWEHSNL 1368
Query: 238 NNSQQNKEKVYIIAHVPVGYLPSSQNITAMREYYNEKLIDIFQKYSDVIAGQ 289
++ +IA+ L S+ +Y N ID ++K + IA Q
Sbjct: 1369 EVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQ 1420
>gi|18860894 protein tyrosine phosphatase, receptor type, D isoform 4
precursor [Homo sapiens]
Length = 1501
Score = 32.7 bits (73), Expect = 0.69
Identities = 28/112 (25%), Positives = 47/112 (41%), Gaps = 12/112 (10%)
Query: 187 LRKGGFYSQKVTTNPNLRIISL---------NTNLYYGPNIMTLNKTDPANQFEWLESTL 237
LR+ F + + ++P + I+ L N NL + ++ DP QF W S L
Sbjct: 910 LRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESI---DPGQQFTWEHSNL 966
Query: 238 NNSQQNKEKVYIIAHVPVGYLPSSQNITAMREYYNEKLIDIFQKYSDVIAGQ 289
++ +IA+ L S+ +Y N ID ++K + IA Q
Sbjct: 967 EVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQ 1018
>gi|20336188 paired basic amino acid cleaving system 4 isoform e
preproprotein [Homo sapiens]
Length = 623
Score = 32.3 bits (72), Expect = 0.91
Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 4/42 (9%)
Query: 162 VVTSKVYNAVANLWKPWLDEEAISTL----RKGGFYSQKVTT 199
+ T V +A N +KPW EE STL G FY +K+ T
Sbjct: 364 IYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVT 405
>gi|20336186 paired basic amino acid cleaving system 4 isoform c
preproprotein [Homo sapiens]
Length = 487
Score = 32.3 bits (72), Expect = 0.91
Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 4/42 (9%)
Query: 162 VVTSKVYNAVANLWKPWLDEEAISTL----RKGGFYSQKVTT 199
+ T V +A N +KPW EE STL G FY +K+ T
Sbjct: 364 IYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVT 405
>gi|27894285 paired basic amino acid cleaving system 4 isoform f
preproprotein [Homo sapiens]
Length = 664
Score = 32.3 bits (72), Expect = 0.91
Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 4/42 (9%)
Query: 162 VVTSKVYNAVANLWKPWLDEEAISTL----RKGGFYSQKVTT 199
+ T V +A N +KPW EE STL G FY +K+ T
Sbjct: 364 IYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVT 405
>gi|20336190 paired basic amino acid cleaving system 4 isoform d
preproprotein [Homo sapiens]
Length = 652
Score = 32.3 bits (72), Expect = 0.91
Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 4/42 (9%)
Query: 162 VVTSKVYNAVANLWKPWLDEEAISTL----RKGGFYSQKVTT 199
+ T V +A N +KPW EE STL G FY +K+ T
Sbjct: 364 IYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVT 405
>gi|20336184 paired basic amino acid cleaving system 4 isoform h
preproprotein [Homo sapiens]
Length = 962
Score = 32.3 bits (72), Expect = 0.91
Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 4/42 (9%)
Query: 162 VVTSKVYNAVANLWKPWLDEEAISTL----RKGGFYSQKVTT 199
+ T V +A N +KPW EE STL G FY +K+ T
Sbjct: 364 IYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVT 405
>gi|20336182 paired basic amino acid cleaving system 4 isoform g
preproprotein [Homo sapiens]
Length = 975
Score = 32.3 bits (72), Expect = 0.91
Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 4/42 (9%)
Query: 162 VVTSKVYNAVANLWKPWLDEEAISTL----RKGGFYSQKVTT 199
+ T V +A N +KPW EE STL G FY +K+ T
Sbjct: 364 IYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVT 405
>gi|4505577 paired basic amino acid cleaving system 4 isoform a
preproprotein [Homo sapiens]
Length = 969
Score = 32.3 bits (72), Expect = 0.91
Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 4/42 (9%)
Query: 162 VVTSKVYNAVANLWKPWLDEEAISTL----RKGGFYSQKVTT 199
+ T V +A N +KPW EE STL G FY +K+ T
Sbjct: 364 IYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVT 405
>gi|20336180 paired basic amino acid cleaving system 4 isoform b
preproprotein [Homo sapiens]
Length = 956
Score = 32.3 bits (72), Expect = 0.91
Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 4/42 (9%)
Query: 162 VVTSKVYNAVANLWKPWLDEEAISTL----RKGGFYSQKVTT 199
+ T V +A N +KPW EE STL G FY +K+ T
Sbjct: 364 IYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVT 405
>gi|27436871 carboxypeptidase O [Homo sapiens]
Length = 374
Score = 31.6 bits (70), Expect = 1.5
Identities = 37/128 (28%), Positives = 54/128 (42%), Gaps = 33/128 (25%)
Query: 267 MREYYNEKLIDIFQKYSDVIAGQFYG---HTHRDSIMVLSDKKGSPVNSL---------- 313
M E Y E + +I +KY +V+ F G TH + +S G+P +
Sbjct: 53 MGEIY-EWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKIIWMDCGIHARE 111
Query: 314 FVAPAVTP--VKSVLEKQTNNPGIRLFQYDPRDYKLLDMLQYYLNLTEANLKGESIWKLE 371
++APA VK +L+ +N IR KLL L +Y+ L N+ G
Sbjct: 112 WIAPAFCQWFVKEILQNHKDNSSIR---------KLLRNLDFYV-LPVLNIDG------- 154
Query: 372 YILTQTYD 379
YI T T D
Sbjct: 155 YIYTWTTD 162
>gi|160420295 hypothetical protein LOC85459 [Homo sapiens]
Length = 2601
Score = 31.2 bits (69), Expect = 2.0
Identities = 23/99 (23%), Positives = 40/99 (40%), Gaps = 12/99 (12%)
Query: 113 PHVPVPELSTDTVINVITNMTTTIQSLFPNLQVFPALGNHDYWPQDQLPVVTSKVYNAVA 172
P V P L TD+VI+V P+ + ++W Q Q ++ Y +
Sbjct: 615 PSVSAPSLITDSVISV------------PSWKSERPTAISEHWDQGQRLKLSPNKYQPIQ 662
Query: 173 NLWKPWLDEEAISTLRKGGFYSQKVTTNPNLRIISLNTN 211
+ L+++ R+ F ++V T LR + TN
Sbjct: 663 PIQTSKLEQDHFQVARQNHFPQRQVETTETLRASDILTN 701
>gi|93277076 CDK5 regulatory subunit associated protein 1-like 1
[Homo sapiens]
Length = 579
Score = 30.8 bits (68), Expect = 2.6
Identities = 56/253 (22%), Positives = 100/253 (39%), Gaps = 36/253 (14%)
Query: 117 VPELSTDTVINVITNMTTTIQSLFPNLQVFPALGNHDYWPQDQLPVVTSKVYN-AVANLW 175
+P++ + +I +I+ T + + + A GN +P D+L + + V +W
Sbjct: 196 LPKIRKNPLIEIISINTGCLNAC-TYCKTKHARGNLASYPIDELVDRAKQSFQEGVCEIW 254
Query: 176 KPWLDEEAISTLRKGGFYSQKVTTNPNLRIISLNTNLYYGPNIMTLNKTDPANQFEWLES 235
T G Y + + TN + L + G ++ L T+P E LE
Sbjct: 255 L---------TSEDTGAYGRDIGTNLPTLLWKLVEVIPEGA-MLRLGMTNPPYILEHLEE 304
Query: 236 TLNNSQQNKEKVYIIAHVPVGYLPSSQNITAMREYY---NEKLIDIFQK-------YSDV 285
N +VY H+PV S + REY ++++D ++ +D+
Sbjct: 305 MAKIL--NHPRVYAFLHIPVQSASDSVLMEMKREYCVADFKRVVDFLKEKVPGITIATDI 362
Query: 286 IAGQFYGHTHRDSIMVLSDKKGSPVNSLFV----------APAVTPVKSVLEKQTNNPGI 335
I G F G T +D + + SLF+ A + V + ++KQ
Sbjct: 363 ICG-FPGETDQDFQETVKLVEEYKFPSLFINQFYPRPGTPAAKMEQVPAQVKKQRTKDLS 421
Query: 336 RLF-QYDPRDYKL 347
R+F Y P D+K+
Sbjct: 422 RVFHSYSPYDHKI 434
>gi|154689817 beta 1,3-galactosyltransferase-like [Homo sapiens]
Length = 498
Score = 30.4 bits (67), Expect = 3.4
Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 14/108 (12%)
Query: 93 DFIKNSGQEASFMIWT-GDSPPHVPVPELSTDTVINVITNMTTTIQSLFP-------NLQ 144
DF + E + IW G PP PVPE T+ +V TT S P
Sbjct: 212 DFTIDLKHEIALYIWDKGGGPPLTPVPEFCTN---DVDFYCATTFHSFLPLCRKPVKKKD 268
Query: 145 VFPALGNHDYWPQDQLPVVTSKVYNAVANLWKPWLD--EEAISTLRKG 190
+F A+ + D++P+V + + + A+L + + D E +I T+ G
Sbjct: 269 IFVAVKTCKKFHGDRIPIV-KQTWESQASLIEYYSDYTENSIPTVDLG 315
>gi|40254462 guanine nucleotide binding protein (G protein), q
polypeptide [Homo sapiens]
Length = 359
Score = 30.0 bits (66), Expect = 4.5
Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 4/45 (8%)
Query: 312 SLFVAPAVTPVKSVLEKQTNNPGIRLFQYDPRDYKLLDMLQYYLN 356
S F P V +KS+ N+PGI+ R+Y+L D +YYLN
Sbjct: 122 SAFENPYVDAIKSLW----NDPGIQECYDRRREYQLSDSTKYYLN 162
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
precursor [Homo sapiens]
Length = 1907
Score = 29.6 bits (65), Expect = 5.9
Identities = 21/88 (23%), Positives = 37/88 (42%), Gaps = 3/88 (3%)
Query: 202 NLRIISLNTNLYYGPNIMTLNKTDPANQFEWLESTLNNSQQNKEKVYIIAHVPVGYLPSS 261
N+ + N L + ++ DP QF W S L ++ +IA+ + +S
Sbjct: 1340 NIERLKANDGLKFSQEYESI---DPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTS 1396
Query: 262 QNITAMREYYNEKLIDIFQKYSDVIAGQ 289
+ +Y N ID ++K + IA Q
Sbjct: 1397 IDGVPGSDYINANYIDGYRKQNAYIATQ 1424
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
precursor [Homo sapiens]
Length = 1898
Score = 29.6 bits (65), Expect = 5.9
Identities = 21/88 (23%), Positives = 37/88 (42%), Gaps = 3/88 (3%)
Query: 202 NLRIISLNTNLYYGPNIMTLNKTDPANQFEWLESTLNNSQQNKEKVYIIAHVPVGYLPSS 261
N+ + N L + ++ DP QF W S L ++ +IA+ + +S
Sbjct: 1331 NIERLKANDGLKFSQEYESI---DPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTS 1387
Query: 262 QNITAMREYYNEKLIDIFQKYSDVIAGQ 289
+ +Y N ID ++K + IA Q
Sbjct: 1388 IDGVPGSDYINANYIDGYRKQNAYIATQ 1415
>gi|11761619 GDP-mannose pyrophosphorylase B isoform 1 [Homo
sapiens]
Length = 387
Score = 29.6 bits (65), Expect = 5.9
Identities = 15/47 (31%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 78 DVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSPPHVPVPELSTDT 124
DV+CD P+Q ++ F ++ GQE S ++ + P V DT
Sbjct: 110 DVICDFPFQAMV---QFHRHHGQEGSILVTKVEEPSKYGVVVCEADT 153
>gi|11761621 GDP-mannose pyrophosphorylase B isoform 2 [Homo
sapiens]
Length = 360
Score = 29.6 bits (65), Expect = 5.9
Identities = 15/47 (31%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 78 DVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSPPHVPVPELSTDT 124
DV+CD P+Q ++ F ++ GQE S ++ + P V DT
Sbjct: 110 DVICDFPFQAMV---QFHRHHGQEGSILVTKVEEPSKYGVVVCEADT 153
>gi|153791876 olfactory receptor, family 6, subfamily Q, member 1
[Homo sapiens]
Length = 317
Score = 29.6 bits (65), Expect = 5.9
Identities = 20/48 (41%), Positives = 25/48 (52%), Gaps = 9/48 (18%)
Query: 409 YFFVSYDS-------SVTCDKTCKAFQICAIMNLDNISYADCLKQLYI 449
YFF+++ S SVT K F + NISYADCL QL+I
Sbjct: 62 YFFLTHLSCLEIWYTSVTVPKMLAGF--IGVDGGKNISYADCLSQLFI 107
>gi|21493045 A-kinase anchor protein 6 [Homo sapiens]
Length = 2319
Score = 29.3 bits (64), Expect = 7.7
Identities = 18/64 (28%), Positives = 31/64 (48%), Gaps = 15/64 (23%)
Query: 41 WHVTDLHLD----PTYHITDDHTKV----------CASSKGANASNPGPFGDVLCDSPYQ 86
W +++++ D PTYH+ HT++ ASS G + + GP D+L D
Sbjct: 669 WELSEMNSDSEIYPTYHVKKKHTRLGRVSPSSSSDIASSLGESIES-GPLSDILSDEESS 727
Query: 87 LILS 90
+ L+
Sbjct: 728 MPLA 731
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,366,166
Number of Sequences: 37866
Number of extensions: 857878
Number of successful extensions: 2180
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 2159
Number of HSP's gapped (non-prelim): 33
length of query: 453
length of database: 18,247,518
effective HSP length: 106
effective length of query: 347
effective length of database: 14,233,722
effective search space: 4939101534
effective search space used: 4939101534
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.